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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= S06A01NCLL0001_J03
         (457 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AK223596-1|BAD97316.1|  647|Homo sapiens dihydrolipoamide S-acet...    69   8e-12
Y00978-1|CAA68787.1|  615|Homo sapiens PDC-E2 precursor (AA -54 ...    69   1e-11
BC039084-1|AAH39084.1|  647|Homo sapiens dihydrolipoamide S-acet...    69   1e-11
X13822-1|CAA32052.1|  220|Homo sapiens dihydrolipoamide S-acetyl...    66   4e-11
J03866-1|AAA62253.1|  613|Homo sapiens dihydrolipoamide acetyltr...    60   4e-09
Y13145-1|CAA73606.1|  501|Homo sapiens protein X protein.              58   1e-08
U82328-1|AAC39661.1|  501|Homo sapiens pyruvate dehydrogenase co...    58   1e-08
U79296-1|AAB50223.1|  375|Homo sapiens dihyrolipoamide acetyl tr...    58   1e-08
BC010389-1|AAH10389.1|  501|Homo sapiens pyruvate dehydrogenase ...    58   1e-08
AJ298105-1|CAC18649.1|  501|Homo sapiens lipoyl-containing compo...    58   1e-08
AF001437-1|AAB66315.1|  501|Homo sapiens dihydrolipoamide dehydr...    58   1e-08
AK074034-1|BAB84860.1|  716|Homo sapiens FLJ00080 protein protein.     31   1.9  
BC112223-1|AAI12224.1|  831|Homo sapiens solute carrier family 3...    29   5.7  
BC101516-1|AAI01517.1|  831|Homo sapiens solute carrier family 3...    29   5.7  
AK126635-1|BAC86624.1|  162|Homo sapiens protein ( Homo sapiens ...    29   5.7  
AB033091-1|BAA86579.1|  835|Homo sapiens KIAA1265 protein protein.     29   5.7  
BC051699-1|AAH51699.2|  443|Homo sapiens POU class 3 homeobox 2 ...    29   7.6  
AK091161-1|BAC03597.1|  143|Homo sapiens protein ( Homo sapiens ...    29   7.6  

>AK223596-1|BAD97316.1|  647|Homo sapiens dihydrolipoamide
           S-acetyltransferase (E2 component of pyruvate
           dehydrogenase co protein.
          Length = 647

 Score = 68.9 bits (161), Expect = 8e-12
 Identities = 46/142 (32%), Positives = 68/142 (47%), Gaps = 7/142 (4%)
 Frame = +1

Query: 49  RIYASPFARRIAELKNFRLGG-QGTGLYGSLKSGDLSDXXXXXXXXXXXXXX------XX 207
           R++ SP A+++A  K   L   +GTG  G +   D+                        
Sbjct: 354 RVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMA 413

Query: 208 XXXXXTFVDLPLSGMRETIARRLTAAKQSIPHYQLVATVNVESTLAMRKLVNDKLAAEKS 387
                 F D+P+S +R  IA+RL  +KQ+IPHY L   VN+   L +RK +N K+   +S
Sbjct: 414 PVPTGVFTDIPISNIRRVIAQRLMQSKQTIPHYYLSINVNMGEVLLVRKELN-KILEGRS 472

Query: 388 DINVSVNDLIVNAVAATCKRVP 453
              +SVND I+ A A  C +VP
Sbjct: 473 --KISVNDFIIKASALACLKVP 492


>Y00978-1|CAA68787.1|  615|Homo sapiens PDC-E2 precursor (AA -54 to
           561) protein.
          Length = 615

 Score = 68.5 bits (160), Expect = 1e-11
 Identities = 46/142 (32%), Positives = 68/142 (47%), Gaps = 7/142 (4%)
 Frame = +1

Query: 49  RIYASPFARRIAELKNFRLGG-QGTGLYGSLKSGDLSDXXXXXXXXXXXXXX------XX 207
           R++ SP A+++A  K   L   +GTG  G +   D+                        
Sbjct: 322 RVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMA 381

Query: 208 XXXXXTFVDLPLSGMRETIARRLTAAKQSIPHYQLVATVNVESTLAMRKLVNDKLAAEKS 387
                 F D+P+S +R  IA+RL  +KQ+IPHY L   VN+   L +RK +N K+   +S
Sbjct: 382 PVPTGVFTDIPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELN-KILEGRS 440

Query: 388 DINVSVNDLIVNAVAATCKRVP 453
              +SVND I+ A A  C +VP
Sbjct: 441 --KISVNDFIIKASALACLKVP 460


>BC039084-1|AAH39084.1|  647|Homo sapiens dihydrolipoamide
           S-acetyltransferase (E2 component of pyruvate
           dehydrogenase co protein.
          Length = 647

 Score = 68.5 bits (160), Expect = 1e-11
 Identities = 46/142 (32%), Positives = 68/142 (47%), Gaps = 7/142 (4%)
 Frame = +1

Query: 49  RIYASPFARRIAELKNFRLGG-QGTGLYGSLKSGDLSDXXXXXXXXXXXXXX------XX 207
           R++ SP A+++A  K   L   +GTG  G +   D+                        
Sbjct: 354 RVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMA 413

Query: 208 XXXXXTFVDLPLSGMRETIARRLTAAKQSIPHYQLVATVNVESTLAMRKLVNDKLAAEKS 387
                 F D+P+S +R  IA+RL  +KQ+IPHY L   VN+   L +RK +N K+   +S
Sbjct: 414 PVPTGVFTDIPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELN-KILEGRS 472

Query: 388 DINVSVNDLIVNAVAATCKRVP 453
              +SVND I+ A A  C +VP
Sbjct: 473 --KISVNDFIIKASALACLKVP 492


>X13822-1|CAA32052.1|  220|Homo sapiens dihydrolipoamide
           S-acetyltransferase protein.
          Length = 220

 Score = 66.5 bits (155), Expect = 4e-11
 Identities = 45/142 (31%), Positives = 67/142 (47%), Gaps = 7/142 (4%)
 Frame = +1

Query: 49  RIYASPFARRIAELKNFRLGG-QGTGLYGSLKSGDLSDXXXXXXXXXXXXXX------XX 207
           R++ SP A+++A  K   L   +GTG  G +   D+                        
Sbjct: 18  RVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMA 77

Query: 208 XXXXXTFVDLPLSGMRETIARRLTAAKQSIPHYQLVATVNVESTLAMRKLVNDKLAAEKS 387
                 F D+P+S +R  IA+RL  +KQ+IPHY L   VN+   L +RK +N K+   +S
Sbjct: 78  PVPTGVFTDIPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELN-KILEGRS 136

Query: 388 DINVSVNDLIVNAVAATCKRVP 453
              +SVND I+   A  C +VP
Sbjct: 137 --KISVNDFIIKRSALACLKVP 156


>J03866-1|AAA62253.1|  613|Homo sapiens dihydrolipoamide
           acetyltransferase protein.
          Length = 613

 Score = 60.1 bits (139), Expect = 4e-09
 Identities = 44/142 (30%), Positives = 67/142 (47%), Gaps = 7/142 (4%)
 Frame = +1

Query: 49  RIYASPFARRIAELKNFRLGG-QGTGLYGSLKSGDLSDXXXXXXXXXXXXXX------XX 207
           R++  P A+++A  K   L   +GTG  G +   D+                        
Sbjct: 321 RVFVDPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMA 380

Query: 208 XXXXXTFVDLPLSGMRETIARRLTAAKQSIPHYQLVATVNVESTLAMRKLVNDKLAAEKS 387
                 F D+P+S +R  IA+RL  +KQ+IPHY L++    E  L +RK +N K+   +S
Sbjct: 381 PVPTGVFTDIPISNIRRVIAQRLMQSKQTIPHYYLLSCKYGE-VLLVRKELN-KILEGRS 438

Query: 388 DINVSVNDLIVNAVAATCKRVP 453
              +SVND I+ A A  C +VP
Sbjct: 439 --KISVNDFIIKASALACLKVP 458


>Y13145-1|CAA73606.1|  501|Homo sapiens protein X protein.
          Length = 501

 Score = 58.4 bits (135), Expect = 1e-08
 Identities = 31/77 (40%), Positives = 47/77 (61%)
 Frame = +1

Query: 223 TFVDLPLSGMRETIARRLTAAKQSIPHYQLVATVNVESTLAMRKLVNDKLAAEKSDINVS 402
           TF ++P S +R  IA+RLT +K ++PH    A  ++ + L +R+   D +   K DI VS
Sbjct: 274 TFTEIPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQ---DLV---KDDIKVS 327

Query: 403 VNDLIVNAVAATCKRVP 453
           VND I+ A A T K++P
Sbjct: 328 VNDFIIKAAAVTLKQMP 344


>U82328-1|AAC39661.1|  501|Homo sapiens pyruvate dehydrogenase
           complex protein X subunit precursor protein.
          Length = 501

 Score = 58.4 bits (135), Expect = 1e-08
 Identities = 31/77 (40%), Positives = 47/77 (61%)
 Frame = +1

Query: 223 TFVDLPLSGMRETIARRLTAAKQSIPHYQLVATVNVESTLAMRKLVNDKLAAEKSDINVS 402
           TF ++P S +R  IA+RLT +K ++PH    A  ++ + L +R+   D +   K DI VS
Sbjct: 274 TFTEIPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQ---DLV---KDDIKVS 327

Query: 403 VNDLIVNAVAATCKRVP 453
           VND I+ A A T K++P
Sbjct: 328 VNDFIIKAAAVTLKQMP 344


>U79296-1|AAB50223.1|  375|Homo sapiens dihyrolipoamide acetyl
           transferase protein.
          Length = 375

 Score = 58.4 bits (135), Expect = 1e-08
 Identities = 31/77 (40%), Positives = 47/77 (61%)
 Frame = +1

Query: 223 TFVDLPLSGMRETIARRLTAAKQSIPHYQLVATVNVESTLAMRKLVNDKLAAEKSDINVS 402
           TF ++P S +R  IA+RLT +K ++PH    A  ++ + L +R+   D +   K DI VS
Sbjct: 148 TFTEIPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQ---DLV---KDDIKVS 201

Query: 403 VNDLIVNAVAATCKRVP 453
           VND I+ A A T K++P
Sbjct: 202 VNDFIIKAAAVTLKQMP 218


>BC010389-1|AAH10389.1|  501|Homo sapiens pyruvate dehydrogenase
           complex, component X protein.
          Length = 501

 Score = 58.4 bits (135), Expect = 1e-08
 Identities = 31/77 (40%), Positives = 47/77 (61%)
 Frame = +1

Query: 223 TFVDLPLSGMRETIARRLTAAKQSIPHYQLVATVNVESTLAMRKLVNDKLAAEKSDINVS 402
           TF ++P S +R  IA+RLT +K ++PH    A  ++ + L +R+   D +   K DI VS
Sbjct: 274 TFTEIPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQ---DLV---KDDIKVS 327

Query: 403 VNDLIVNAVAATCKRVP 453
           VND I+ A A T K++P
Sbjct: 328 VNDFIIKAAAVTLKQMP 344


>AJ298105-1|CAC18649.1|  501|Homo sapiens lipoyl-containing
           component X protein.
          Length = 501

 Score = 58.4 bits (135), Expect = 1e-08
 Identities = 31/77 (40%), Positives = 47/77 (61%)
 Frame = +1

Query: 223 TFVDLPLSGMRETIARRLTAAKQSIPHYQLVATVNVESTLAMRKLVNDKLAAEKSDINVS 402
           TF ++P S +R  IA+RLT +K ++PH    A  ++ + L +R+   D +   K DI VS
Sbjct: 274 TFTEIPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQ---DLV---KDDIKVS 327

Query: 403 VNDLIVNAVAATCKRVP 453
           VND I+ A A T K++P
Sbjct: 328 VNDFIIKAAAVTLKQMP 344


>AF001437-1|AAB66315.1|  501|Homo sapiens dihydrolipoamide
           dehydrogenase-binding protein protein.
          Length = 501

 Score = 58.4 bits (135), Expect = 1e-08
 Identities = 31/77 (40%), Positives = 47/77 (61%)
 Frame = +1

Query: 223 TFVDLPLSGMRETIARRLTAAKQSIPHYQLVATVNVESTLAMRKLVNDKLAAEKSDINVS 402
           TF ++P S +R  IA+RLT +K ++PH    A  ++ + L +R+   D +   K DI VS
Sbjct: 274 TFTEIPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQ---DLV---KDDIKVS 327

Query: 403 VNDLIVNAVAATCKRVP 453
           VND I+ A A T K++P
Sbjct: 328 VNDFIIKAAAVTLKQMP 344


>AK074034-1|BAB84860.1|  716|Homo sapiens FLJ00080 protein protein.
          Length = 716

 Score = 31.1 bits (67), Expect = 1.9
 Identities = 16/41 (39%), Positives = 18/41 (43%)
 Frame = +3

Query: 198 GTGTGSGRYVRGLAPERHAGDHRPSPHSRQAKHPALPARCH 320
           G+  G  R +R   P RHAG H PSP      H    A  H
Sbjct: 18  GSSQGPHRQIRPPPPCRHAGTHVPSPLPHTQVHRRRQAYAH 58


>BC112223-1|AAI12224.1|  831|Homo sapiens solute carrier family 39
           (zinc transporter), member 10 protein.
          Length = 831

 Score = 29.5 bits (63), Expect = 5.7
 Identities = 12/21 (57%), Positives = 16/21 (76%)
 Frame = -2

Query: 390 VGFLSGELVVDQLPHSQGGLD 328
           VG +SG+ ++  LPHSQGG D
Sbjct: 448 VGTMSGDALLHLLPHSQGGHD 468


>BC101516-1|AAI01517.1|  831|Homo sapiens solute carrier family 39
           (zinc transporter), member 10 protein.
          Length = 831

 Score = 29.5 bits (63), Expect = 5.7
 Identities = 12/21 (57%), Positives = 16/21 (76%)
 Frame = -2

Query: 390 VGFLSGELVVDQLPHSQGGLD 328
           VG +SG+ ++  LPHSQGG D
Sbjct: 448 VGTMSGDALLHLLPHSQGGHD 468


>AK126635-1|BAC86624.1|  162|Homo sapiens protein ( Homo sapiens
           cDNA FLJ44677 fis, clone BRACE3009265. ).
          Length = 162

 Score = 29.5 bits (63), Expect = 5.7
 Identities = 19/52 (36%), Positives = 23/52 (44%), Gaps = 3/52 (5%)
 Frame = +3

Query: 150 PIRCSAGRVWRWGVAAGT-GTGSGRYVRGLAPERH-AGDHRPSP-HSRQAKH 296
           P  C   R WRW   AGT    +GR V G   +R   G    +P H+R   H
Sbjct: 34  PCPCRRRRGWRWWPPAGTPAAAAGRTVEGAGSDRDPKGRTASAPQHARGQGH 85


>AB033091-1|BAA86579.1|  835|Homo sapiens KIAA1265 protein protein.
          Length = 835

 Score = 29.5 bits (63), Expect = 5.7
 Identities = 12/21 (57%), Positives = 16/21 (76%)
 Frame = -2

Query: 390 VGFLSGELVVDQLPHSQGGLD 328
           VG +SG+ ++  LPHSQGG D
Sbjct: 452 VGTMSGDALLHLLPHSQGGHD 472


>BC051699-1|AAH51699.2|  443|Homo sapiens POU class 3 homeobox 2
           protein.
          Length = 443

 Score = 29.1 bits (62), Expect = 7.6
 Identities = 15/44 (34%), Positives = 19/44 (43%), Gaps = 3/44 (6%)
 Frame = +3

Query: 186 GVAAGTGTGSGRYVRGLAP---ERHAGDHRPSPHSRQAKHPALP 308
           G+    G  +G +  GL     E H  DH P PHS   + P  P
Sbjct: 199 GMLGAGGQSAGLHHHGLRDAHDEPHHADHHPHPHSHPHQQPPPP 242


>AK091161-1|BAC03597.1|  143|Homo sapiens protein ( Homo sapiens
           cDNA FLJ33842 fis, clone CTONG2005049. ).
          Length = 143

 Score = 29.1 bits (62), Expect = 7.6
 Identities = 21/46 (45%), Positives = 24/46 (52%)
 Frame = +3

Query: 156 RCSAGRVWRWGVAAGTGTGSGRYVRGLAPERHAGDHRPSPHSRQAK 293
           R  AGR  R G  A   T S   +RG APE   G  RPS  SR+A+
Sbjct: 91  RDRAGRA-RKGEGAAASTLSS--LRGAAPEAGRGARRPSGPSREAQ 133


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.317    0.132    0.359 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 52,101,628
Number of Sequences: 237096
Number of extensions: 933425
Number of successful extensions: 6394
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 6307
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6383
length of database: 76,859,062
effective HSP length: 84
effective length of database: 56,942,998
effective search space used: 3815180866
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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