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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= S06A01NCLL0001_I13
         (481 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q9BXS5 Cluster: AP-1 complex subunit mu-1; n=137; Eukar...   254   1e-66
UniRef50_Q7RKU6 Cluster: Clathrin coat assembly protein ap54; n=...   198   5e-50
UniRef50_Q22B93 Cluster: Adaptor complexes medium subunit family...   177   1e-43
UniRef50_Q4N7V8 Cluster: Clathrin medium chain, putative; n=6; A...   176   2e-43
UniRef50_A2FR45 Cluster: Mu adaptin, putative; n=1; Trichomonas ...   173   2e-42
UniRef50_Q9SGX7 Cluster: F20B24.16; n=4; Magnoliophyta|Rep: F20B...   169   3e-41
UniRef50_Q00776 Cluster: AP-1 complex subunit mu-1 (Mu(1)-adapti...   169   4e-41
UniRef50_A5E396 Cluster: AP-1 complex subunit mu-1; n=6; Sacchar...   164   8e-40
UniRef50_Q014Q3 Cluster: Clathrin adaptor complexes medium subun...   139   3e-32
UniRef50_Q4RWQ3 Cluster: Chromosome 15 SCAF14981, whole genome s...   135   6e-31
UniRef50_Q6C119 Cluster: Similar to sp|Q00776 Saccharomyces cere...   134   7e-31
UniRef50_Q4QBN3 Cluster: Adaptor complex AP-1 medium subunit, pu...   130   2e-29
UniRef50_Q22V00 Cluster: Adaptor complexes medium subunit family...   116   2e-25
UniRef50_Q6CC50 Cluster: Yarrowia lipolytica chromosome C of str...   110   1e-23
UniRef50_Q5A2L1 Cluster: Potential clathrin-associated protein A...    93   4e-18
UniRef50_Q1EQ16 Cluster: Mu 2 subunit isoform 2; n=1; Entamoeba ...    92   7e-18
UniRef50_Q00U04 Cluster: Clathrin adaptor complexes medium subun...    88   1e-16
UniRef50_Q96CW1 Cluster: AP-2 complex subunit mu-1; n=94; Fungi/...    88   1e-16
UniRef50_A3LVW0 Cluster: Predicted protein; n=2; Pichia|Rep: Pre...    87   2e-16
UniRef50_Q3E8F7 Cluster: Uncharacterized protein At5g46630.2; n=...    87   3e-16
UniRef50_P35603 Cluster: AP-2 complex subunit mu; n=23; Eukaryot...    86   4e-16
UniRef50_Q5AJY3 Cluster: Putative uncharacterized protein; n=1; ...    85   1e-15
UniRef50_Q1JSZ4 Cluster: Clathrin coat assembly protein, putativ...    83   2e-15
UniRef50_A2ER69 Cluster: Adaptor complexes medium subunit family...    83   3e-15
UniRef50_Q09718 Cluster: AP-2 complex subunit mu; n=1; Schizosac...    83   4e-15
UniRef50_Q99186 Cluster: AP-2 complex subunit mu; n=2; Saccharom...    80   2e-14
UniRef50_Q7QZ95 Cluster: GLP_567_48751_50055; n=2; Giardia intes...    78   9e-14
UniRef50_Q6CUL9 Cluster: Similar to sp|Q99186 Saccharomyces cere...    77   2e-13
UniRef50_A7ST88 Cluster: Predicted protein; n=1; Nematostella ve...    75   8e-13
UniRef50_Q5CWB6 Cluster: Clathrin coat assembly protein AP50; n=...    73   4e-12
UniRef50_A0BJZ5 Cluster: Chromosome undetermined scaffold_111, w...    69   4e-11
UniRef50_Q9SB50 Cluster: Clathrin coat assembly like protein; n=...    69   7e-11
UniRef50_Q4DZV1 Cluster: Clathrin coat assembly protein, putativ...    68   1e-10
UniRef50_Q7QT00 Cluster: GLP_384_5522_6868; n=2; Giardia intesti...    65   7e-10
UniRef50_A5JZZ1 Cluster: Clathrin coat assembly protein AP50, pu...    65   9e-10
UniRef50_UPI0000583F86 Cluster: PREDICTED: similar to MGC81080 p...    64   1e-09
UniRef50_Q7RAH7 Cluster: Clathrin coat assembly protein ap50; n=...    64   2e-09
UniRef50_Q4Q1B6 Cluster: Clathrin coat assembly protein-like pro...    64   2e-09
UniRef50_Q759G1 Cluster: ADR315Wp; n=1; Eremothecium gossypii|Re...    62   8e-09
UniRef50_Q4SPT3 Cluster: Chromosome 7 SCAF14536, whole genome sh...    58   1e-07
UniRef50_A7AS46 Cluster: Clathrin coat adaptor subunit, putative...    58   1e-07
UniRef50_A4S949 Cluster: Predicted protein; n=2; Ostreococcus|Re...    57   2e-07
UniRef50_A7AUL5 Cluster: Clathrin coat assembly protein, putativ...    55   7e-07
UniRef50_A5K4K8 Cluster: Adapter-related protein complex 4 mu 1 ...    55   1e-06
UniRef50_Q550G8 Cluster: Clathrin-adaptor medium chain apm 4; n=...    54   2e-06
UniRef50_A7TLM0 Cluster: Putative uncharacterized protein; n=1; ...    53   3e-06
UniRef50_Q6CIM6 Cluster: Kluyveromyces lactis strain NRRL Y-1140...    52   5e-06
UniRef50_UPI0000DD86A9 Cluster: PREDICTED: similar to AP-1 compl...    42   9e-06
UniRef50_Q75DH8 Cluster: ABR047Wp; n=1; Eremothecium gossypii|Re...    49   5e-05
UniRef50_P38700 Cluster: Adaptin medium chain homolog APM2; n=3;...    48   1e-04
UniRef50_A5DHF6 Cluster: Putative uncharacterized protein; n=1; ...    48   1e-04
UniRef50_O00189 Cluster: AP-4 complex subunit mu-1; n=34; Euther...    47   3e-04
UniRef50_A5DV27 Cluster: Putative uncharacterized protein; n=1; ...    44   0.001
UniRef50_Q5ACY9 Cluster: Potential clathrin-associated protein A...    42   0.005
UniRef50_Q6BIP8 Cluster: Similar to CA4819|IPF1194 Candida albic...    42   0.007
UniRef50_Q8SSH2 Cluster: CLATHRIN COAT ASSEMBLY PROTEIN; n=1; En...    41   0.013
UniRef50_A2DA54 Cluster: Adaptor complexes medium subunit family...    38   0.12 
UniRef50_A5DI41 Cluster: Putative uncharacterized protein; n=1; ...    37   0.20 
UniRef50_Q4N810 Cluster: Adaptin medium chain, putative; n=2; Th...    37   0.27 
UniRef50_Q5BY00 Cluster: SJCHGC04843 protein; n=1; Schistosoma j...    33   2.5  
UniRef50_Q8WXE9 Cluster: Stonin-2; n=26; Tetrapoda|Rep: Stonin-2...    33   2.5  
UniRef50_A2E9B8 Cluster: Adaptor complexes medium subunit family...    33   3.3  
UniRef50_Q552M0 Cluster: Putative uncharacterized protein; n=1; ...    33   4.4  
UniRef50_Q9Y6Q2 Cluster: Stonin-1; n=51; Tetrapoda|Rep: Stonin-1...    33   4.4  
UniRef50_Q93Y22 Cluster: Coatomer subunit delta; n=24; Eukaryota...    33   4.4  
UniRef50_Q0U9R8 Cluster: Putative uncharacterized protein; n=1; ...    32   5.8  
UniRef50_Q3T8J9 Cluster: GON-4-like protein; n=45; Eutheria|Rep:...    32   5.8  
UniRef50_A6EML1 Cluster: Branched-chain-amino-acid transaminase;...    32   7.7  
UniRef50_Q5TX05 Cluster: ENSANGP00000029503; n=2; Culicidae|Rep:...    32   7.7  

>UniRef50_Q9BXS5 Cluster: AP-1 complex subunit mu-1; n=137;
           Eukaryota|Rep: AP-1 complex subunit mu-1 - Homo sapiens
           (Human)
          Length = 423

 Score =  254 bits (621), Expect = 1e-66
 Identities = 117/134 (87%), Positives = 124/134 (92%)
 Frame = +2

Query: 8   ARVEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIKSF 187
           +R+EYMIKAKSQFKRRSTANNVEI IPVP DADSPKFKTT+GSVK+ PE + I WSIKSF
Sbjct: 289 SRIEYMIKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKWVPENSEIVWSIKSF 348

Query: 188 PGGKEYLMRAHFGLPSVVCEEVDGKPPIQVKFEIPYFTTSGIQVRYLKIIEKSGYQALPW 367
           PGGKEYLMRAHFGLPSV  E+ +GKPPI VKFEIPYFTTSGIQVRYLKIIEKSGYQALPW
Sbjct: 349 PGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKIIEKSGYQALPW 408

Query: 368 VRYITQNGDYQLRT 409
           VRYITQNGDYQLRT
Sbjct: 409 VRYITQNGDYQLRT 422


>UniRef50_Q7RKU6 Cluster: Clathrin coat assembly protein ap54; n=8;
           Eukaryota|Rep: Clathrin coat assembly protein ap54 -
           Plasmodium yoelii yoelii
          Length = 459

 Score =  198 bits (483), Expect = 5e-50
 Identities = 91/135 (67%), Positives = 108/135 (80%), Gaps = 3/135 (2%)
 Frame = +2

Query: 11  RVEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIKSFP 190
           ++EY++KAKSQFK +S ANNVE  +PVPAD DSP F+T IG+VKY P+++ + W IK F 
Sbjct: 323 KIEYIVKAKSQFKNKSIANNVEFHLPVPADVDSPHFQTYIGTVKYYPDKDILLWKIKQFQ 382

Query: 191 GGKEYLMRAHFGLPSVVCEE---VDGKPPIQVKFEIPYFTTSGIQVRYLKIIEKSGYQAL 361
           G KEY+M A FGLPS+V  E   +  K P+ VKFEIPYFT SGI VRYLKIIEKSGYQAL
Sbjct: 383 GQKEYIMNAQFGLPSIVSNENKDIYYKRPVNVKFEIPYFTVSGITVRYLKIIEKSGYQAL 442

Query: 362 PWVRYITQNGDYQLR 406
           PWVRYITQNGDYQ+R
Sbjct: 443 PWVRYITQNGDYQVR 457


>UniRef50_Q22B93 Cluster: Adaptor complexes medium subunit family
           protein; n=3; Tetrahymena thermophila|Rep: Adaptor
           complexes medium subunit family protein - Tetrahymena
           thermophila SB210
          Length = 444

 Score =  177 bits (431), Expect = 1e-43
 Identities = 81/134 (60%), Positives = 100/134 (74%), Gaps = 2/134 (1%)
 Frame = +2

Query: 11  RVEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIKSFP 190
           ++E+ +K KS FK++STANNVEI IPVP DA++P FK   G+V+Y  E+ A+ W  K FP
Sbjct: 309 KIEFTVKVKSNFKQKSTANNVEIFIPVPDDAETPVFKAAYGTVEYVAEKEAMGWKFKQFP 368

Query: 191 GGKEYLMRAHFGLPSVVC--EEVDGKPPIQVKFEIPYFTTSGIQVRYLKIIEKSGYQALP 364
           G +EY+M A F LP+VV    E   + PI + FEIPY+T SG QVRYLKI EKSGY ALP
Sbjct: 369 GQREYMMTATFHLPTVVSPNREKFQRMPISINFEIPYYTVSGFQVRYLKIQEKSGYHALP 428

Query: 365 WVRYITQNGDYQLR 406
           WVRYITQNGDYQ+R
Sbjct: 429 WVRYITQNGDYQIR 442


>UniRef50_Q4N7V8 Cluster: Clathrin medium chain, putative; n=6;
           Alveolata|Rep: Clathrin medium chain, putative -
           Theileria parva
          Length = 452

 Score =  176 bits (428), Expect = 2e-43
 Identities = 80/134 (59%), Positives = 103/134 (76%), Gaps = 2/134 (1%)
 Frame = +2

Query: 11  RVEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIKSFP 190
           R+E+ +KA SQFK +S A NVE +IPVP+D + P+F  T GSVKY P+Q+AITW +K F 
Sbjct: 317 RIEFYVKATSQFKSKSMATNVEFLIPVPSDVNCPEFNPTQGSVKYLPDQDAITWYVKQFQ 376

Query: 191 GGKEYLMRAHFGLPSVVCEEVD--GKPPIQVKFEIPYFTTSGIQVRYLKIIEKSGYQALP 364
           G K Y M A FGLPSV  E  +   K P+++KFEIPY+T SGI V++L+I +K+GY+ALP
Sbjct: 377 GDKVYTMFASFGLPSVSDESRNTFSKNPVKIKFEIPYYTVSGINVKHLRITDKTGYKALP 436

Query: 365 WVRYITQNGDYQLR 406
           WVRYIT+NGDYQLR
Sbjct: 437 WVRYITKNGDYQLR 450


>UniRef50_A2FR45 Cluster: Mu adaptin, putative; n=1; Trichomonas
           vaginalis G3|Rep: Mu adaptin, putative - Trichomonas
           vaginalis G3
          Length = 426

 Score =  173 bits (421), Expect = 2e-42
 Identities = 73/134 (54%), Positives = 104/134 (77%)
 Frame = +2

Query: 8   ARVEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIKSF 187
           +RVE +I+A++Q++ +S A NV I +PVP D D+PK + T G ++Y+P  NA+ W+IK F
Sbjct: 293 SRVEMLIRARAQYRPQSVAQNVTIRVPVPPDVDTPKAQCTAGRMRYSPNDNALVWTIKQF 352

Query: 188 PGGKEYLMRAHFGLPSVVCEEVDGKPPIQVKFEIPYFTTSGIQVRYLKIIEKSGYQALPW 367
           PG K++ +RAHFGLPSV  EE + K PI V FEIP+FT SG++V+YLK+IE++GYQA+ W
Sbjct: 353 PGRKQFSLRAHFGLPSVESEEEESKRPIVVNFEIPFFTVSGLRVQYLKVIEQTGYQAVTW 412

Query: 368 VRYITQNGDYQLRT 409
           VRY+T +G Y+ RT
Sbjct: 413 VRYLTTDGTYEFRT 426


>UniRef50_Q9SGX7 Cluster: F20B24.16; n=4; Magnoliophyta|Rep:
           F20B24.16 - Arabidopsis thaliana (Mouse-ear cress)
          Length = 411

 Score =  169 bits (411), Expect = 3e-41
 Identities = 80/135 (59%), Positives = 102/135 (75%), Gaps = 2/135 (1%)
 Frame = +2

Query: 8   ARVEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIKSF 187
           +RVE ++KA+SQFK RS A +VEI +PVP DA +P  +T++GS  Y PE++A+ W I+ F
Sbjct: 275 SRVEMLVKARSQFKDRSYATSVEIELPVPTDAYNPDVRTSLGSAAYAPEKDALVWKIQYF 334

Query: 188 PGGKEYLMRAHFGLPSVVCEEV--DGKPPIQVKFEIPYFTTSGIQVRYLKIIEKSGYQAL 361
            G KE+ ++A F LPS+  EE   + K PI+VKFEIP F  SGIQVRYLKIIEKSGYQA 
Sbjct: 335 YGNKEHTLKADFHLPSIAAEEATPERKAPIRVKFEIPKFIVSGIQVRYLKIIEKSGYQAH 394

Query: 362 PWVRYITQNGDYQLR 406
           PWVRYIT  G+Y+LR
Sbjct: 395 PWVRYITMAGEYELR 409


>UniRef50_Q00776 Cluster: AP-1 complex subunit mu-1 (Mu(1)-adaptin);
           n=5; Saccharomycetales|Rep: AP-1 complex subunit mu-1
           (Mu(1)-adaptin) - Saccharomyces cerevisiae (Baker's
           yeast)
          Length = 475

 Score =  169 bits (410), Expect = 4e-41
 Identities = 88/147 (59%), Positives = 107/147 (72%), Gaps = 14/147 (9%)
 Frame = +2

Query: 8   ARVEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIKSF 187
           +R+E   KAK+Q KR+STA NVEI+IPVP DAD+P FK + GS+KY PE++AI W I+SF
Sbjct: 328 SRIEIHCKAKAQIKRKSTATNVEILIPVPDDADTPTFKYSHGSLKYVPEKSAILWKIRSF 387

Query: 188 PGGKEYLMRAHFGLPSVVCEEVDG------------KPPIQVKFEIPYFTTSGIQVRYLK 331
           PGGKEY M A  GLPS+   E DG            K P+Q+KF+IPYFTTSGIQVRYLK
Sbjct: 388 PGGKEYSMSAELGLPSISNNE-DGNRTMPKSNAEILKGPVQIKFQIPYFTTSGIQVRYLK 446

Query: 332 IIE-KSGYQALPWVRYITQNG-DYQLR 406
           I E K  Y++ PWVRYITQ+G DY +R
Sbjct: 447 INEPKLQYKSYPWVRYITQSGDDYTIR 473


>UniRef50_A5E396 Cluster: AP-1 complex subunit mu-1; n=6;
           Saccharomycetales|Rep: AP-1 complex subunit mu-1 -
           Lodderomyces elongisporus (Yeast) (Saccharomyces
           elongisporus)
          Length = 445

 Score =  164 bits (399), Expect = 8e-40
 Identities = 78/138 (56%), Positives = 103/138 (74%), Gaps = 4/138 (2%)
 Frame = +2

Query: 8   ARVEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIKSF 187
           +R+E +   ++Q K++STANNVE+IIP+P DADSPKF    GSVK+ PE++ + W +K+F
Sbjct: 307 SRIEIVCTVRAQIKKKSTANNVEVIIPIPDDADSPKFNPEYGSVKWIPEKSCLVWKLKTF 366

Query: 188 PGGKEYLMRAHFGLPSVV--CEEVDGKPPIQVKFEIPYFTTSGIQVRYLKIIE-KSGYQA 358
           PGGK + M A  GLP+V+   E +  K PI+V F IPYFTTSGIQVRYL+I E K  YQ+
Sbjct: 367 PGGKLFTMSAELGLPAVMDDTENILSKKPIKVNFSIPYFTTSGIQVRYLRINEPKLQYQS 426

Query: 359 LPWVRYITQNG-DYQLRT 409
            PWVRYIT++G DY +RT
Sbjct: 427 YPWVRYITKSGEDYIVRT 444


>UniRef50_Q014Q3 Cluster: Clathrin adaptor complexes medium subunit
           family protein; n=2; Ostreococcus|Rep: Clathrin adaptor
           complexes medium subunit family protein - Ostreococcus
           tauri
          Length = 452

 Score =  139 bits (337), Expect = 3e-32
 Identities = 64/133 (48%), Positives = 91/133 (68%), Gaps = 2/133 (1%)
 Frame = +2

Query: 14  VEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIKSFPG 193
           VEY +   + FK ++ A+NV I IPV ADA SP+ + + GSV Y PE + +TW++K+  G
Sbjct: 317 VEYTVNLSTLFKEQNMASNVRIEIPVAADATSPEIQCSHGSVVYQPEDDVLTWTLKNVKG 376

Query: 194 GKEYLMRAHFGLPSVVCEEVDGKP--PIQVKFEIPYFTTSGIQVRYLKIIEKSGYQALPW 367
            +E+ ++A   LPS   ++   K   P++V FE+PY T SG+QV+YLK+IEK GY ALPW
Sbjct: 377 KREFKLQAKLHLPSTGVKQTRRKTSVPVRVSFEVPYTTASGLQVKYLKVIEKEGYTALPW 436

Query: 368 VRYITQNGDYQLR 406
           VRYIT++ DY  R
Sbjct: 437 VRYITRSDDYAFR 449


>UniRef50_Q4RWQ3 Cluster: Chromosome 15 SCAF14981, whole genome
           shotgun sequence; n=2; Euteleostomi|Rep: Chromosome 15
           SCAF14981, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 128

 Score =  135 bits (326), Expect = 6e-31
 Identities = 61/67 (91%), Positives = 63/67 (94%)
 Frame = +2

Query: 191 GGKEYLMRAHFGLPSVVCEEVDGKPPIQVKFEIPYFTTSGIQVRYLKIIEKSGYQALPWV 370
           GGKEYLMRAHFGLPSV  E+ +GKPPI VKFEIPYFTTSGIQVRYLKIIEKSGYQALPWV
Sbjct: 4   GGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKIIEKSGYQALPWV 63

Query: 371 RYITQNG 391
           RYITQNG
Sbjct: 64  RYITQNG 70


>UniRef50_Q6C119 Cluster: Similar to sp|Q00776 Saccharomyces
           cerevisiae YPL259c APM1 AP-1 complex subunit; n=1;
           Yarrowia lipolytica|Rep: Similar to sp|Q00776
           Saccharomyces cerevisiae YPL259c APM1 AP-1 complex
           subunit - Yarrowia lipolytica (Candida lipolytica)
          Length = 514

 Score =  134 bits (325), Expect = 7e-31
 Identities = 69/142 (48%), Positives = 94/142 (66%), Gaps = 14/142 (9%)
 Frame = +2

Query: 11  RVEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIKSFP 190
           R+   +K KSQF++RSTAN+VE+ +PVP DA SP+F+ T G+V Y PE+NAI W IK   
Sbjct: 340 RLLISVKLKSQFRKRSTANDVEVFVPVPPDATSPRFRATAGTVVYMPERNAIRWKIKQLQ 399

Query: 191 -GGKEYLMRAHFGLPSVVCE--------EVDGKP----PIQVKFEIPYFTTSGIQVRYLK 331
            GGKE+ M+A   +     +         ++  P    P+QV FEIPY+  SG+QVRYLK
Sbjct: 400 GGGKEFSMKAEISVSRTEEQGESLSELLHLNNTPQSQIPVQVTFEIPYYAMSGLQVRYLK 459

Query: 332 IIEKS-GYQALPWVRYITQNGD 394
           + E +  Y++LPWVRYIT+NGD
Sbjct: 460 VNEPTLKYRSLPWVRYITKNGD 481


>UniRef50_Q4QBN3 Cluster: Adaptor complex AP-1 medium subunit,
           putative; n=8; Trypanosomatidae|Rep: Adaptor complex
           AP-1 medium subunit, putative - Leishmania major
          Length = 433

 Score =  130 bits (314), Expect = 2e-29
 Identities = 56/136 (41%), Positives = 88/136 (64%), Gaps = 2/136 (1%)
 Frame = +2

Query: 11  RVEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIKSFP 190
           RV+     +++++   TAN +E+ IP+P+DAD P+  +  G ++Y P+ NA+ W++    
Sbjct: 298 RVKVQCTLQTKYRASLTANEMEVYIPIPSDADCPQSNSQTGHLQYAPQMNALIWNLGKIA 357

Query: 191 GGKEYLMRAHFGLPSVVCEEVD--GKPPIQVKFEIPYFTTSGIQVRYLKIIEKSGYQALP 364
           G +     A F LPS+   ++    K P++V+F IPYF  SG QVRY+K+ EKS Y A P
Sbjct: 358 GNRHCSCSAEFHLPSIRSSDMKDLSKMPVKVRFVIPYFAASGFQVRYVKVSEKSNYVATP 417

Query: 365 WVRYITQNGDYQLRTN 412
           WVRY+TQ+G Y++RT+
Sbjct: 418 WVRYVTQSGVYEIRTD 433


>UniRef50_Q22V00 Cluster: Adaptor complexes medium subunit family
           protein; n=5; Oligohymenophorea|Rep: Adaptor complexes
           medium subunit family protein - Tetrahymena thermophila
           SB210
          Length = 433

 Score =  116 bits (280), Expect = 2e-25
 Identities = 53/128 (41%), Positives = 76/128 (59%)
 Frame = +2

Query: 14  VEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIKSFPG 193
           +E  +K KS F +   A NV + +P P +  +     +IG  KY PEQ  I W IK F G
Sbjct: 302 IEVRVKLKSIFDKTQYATNVALKVPCPKNTANTSNTASIGRAKYEPEQGGIVWRIKKFQG 361

Query: 194 GKEYLMRAHFGLPSVVCEEVDGKPPIQVKFEIPYFTTSGIQVRYLKIIEKSGYQALPWVR 373
             E L+R    L +   ++   KPPI ++F++P FT SG++VR+L+I EKSGY    W+R
Sbjct: 362 ETEALLRCEIVLSNTALDKNWVKPPISLEFQVPSFTASGLRVRFLRIHEKSGYHPTKWIR 421

Query: 374 YITQNGDY 397
           YIT+ G+Y
Sbjct: 422 YITKGGEY 429


>UniRef50_Q6CC50 Cluster: Yarrowia lipolytica chromosome C of strain
           CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
           lipolytica|Rep: Yarrowia lipolytica chromosome C of
           strain CLIB122 of Yarrowia lipolytica - Yarrowia
           lipolytica (Candida lipolytica)
          Length = 419

 Score =  110 bits (265), Expect = 1e-23
 Identities = 54/134 (40%), Positives = 72/134 (53%)
 Frame = +2

Query: 5   EARVEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIKS 184
           ++RVEY I  K+ F ++ TA NV I IP P +A       + G  KY    N I W +  
Sbjct: 285 KSRVEYDIVIKANFPKQQTATNVVINIPTPRNAAKTTINASNGKAKYDSSTNQIVWKVSR 344

Query: 185 FPGGKEYLMRAHFGLPSVVCEEVDGKPPIQVKFEIPYFTTSGIQVRYLKIIEKSGYQALP 364
             GG E  +RA   L     +    KPPI + FEI   T SG+ VRYLK+ EKS Y  + 
Sbjct: 345 ISGGSEISLRATAELTFTTEKTPWNKPPISMDFEITMITCSGLVVRYLKVFEKSNYNTVK 404

Query: 365 WVRYITQNGDYQLR 406
           WVRY+ + G Y++R
Sbjct: 405 WVRYLMKGGSYEIR 418


>UniRef50_Q5A2L1 Cluster: Potential clathrin-associated protein AP-2
           complex component; n=3; Saccharomycetales|Rep: Potential
           clathrin-associated protein AP-2 complex component -
           Candida albicans (Yeast)
          Length = 470

 Score = 92.7 bits (220), Expect = 4e-18
 Identities = 45/135 (33%), Positives = 80/135 (59%), Gaps = 2/135 (1%)
 Frame = +2

Query: 8   ARVEYMIKAKSQFKRRSTANNVEIIIPVPADADS-PKFKTTIGSVKYTPEQNAITWSIKS 184
           +++ Y I+ KS F  +  A NV + IP P          ++IG  K+ PE N+I+W    
Sbjct: 335 SKLMYKIRIKSFFPEKLPATNVSLKIPTPRGGTILSNLSSSIGKTKFHPEDNSISWKCNK 394

Query: 185 FPGGKEYLMRAHFGLPSVVCEEVDG-KPPIQVKFEIPYFTTSGIQVRYLKIIEKSGYQAL 361
           F G +E+++ A   + S   E +   +PPI++ F +  F++SG+ V++L++ EK+ Y+ +
Sbjct: 395 FFGEQEHVLTAEIEVNSSSDELLYWTRPPIKLDFFLDMFSSSGLTVKFLRVQEKNNYRTV 454

Query: 362 PWVRYITQNGDYQLR 406
            WV+Y TQ+G Y++R
Sbjct: 455 KWVKYGTQSGSYEIR 469


>UniRef50_Q1EQ16 Cluster: Mu 2 subunit isoform 2; n=1; Entamoeba
           histolytica|Rep: Mu 2 subunit isoform 2 - Entamoeba
           histolytica
          Length = 407

 Score = 91.9 bits (218), Expect = 7e-18
 Identities = 51/127 (40%), Positives = 65/127 (51%)
 Frame = +2

Query: 26  IKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIKSFPGGKEY 205
           I  ++ F       NV I IPVP +A   K + T GS KY PE  AI W I  F G  + 
Sbjct: 282 INVRALFSELQYGENVRIKIPVPKNAALCKTRCTAGSAKYHPEHAAILWRISRFNGKTQQ 341

Query: 206 LMRAHFGLPSVVCEEVDGKPPIQVKFEIPYFTTSGIQVRYLKIIEKSGYQALPWVRYITQ 385
            +     L      +   KPPI + F IP  T +G+Q+RYLKI   S Y+ + WVRYIT+
Sbjct: 342 TITVDVDLVQTTQSQRWDKPPILMDFVIPALTATGLQIRYLKI--ASDYKTIKWVRYITK 399

Query: 386 NGDYQLR 406
            G  Q R
Sbjct: 400 AGAIQYR 406


>UniRef50_Q00U04 Cluster: Clathrin adaptor complexes medium subunit
           family protein; n=2; Ostreococcus|Rep: Clathrin adaptor
           complexes medium subunit family protein - Ostreococcus
           tauri
          Length = 496

 Score = 87.8 bits (208), Expect = 1e-16
 Identities = 41/131 (31%), Positives = 69/131 (52%), Gaps = 3/131 (2%)
 Frame = +2

Query: 11  RVEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIKSFP 190
           R+   +  +S +   + AN V + IPVP        + + G  KY PE+  + W IK   
Sbjct: 350 RLAMSVNLRSLYDPSTVANEVRVRIPVPKLTARATIRVSAGKAKYVPEEGCLRWKIKKLA 409

Query: 191 GGKEYLMRAHFGLPSVVCEEVDG-KPPIQVKFEIPYFTTSGIQVRYLKIIEKS--GYQAL 361
           G +E  + A   L + + +     +PPI ++F +P FT SG+++R+L + E++   Y   
Sbjct: 410 GHQELQLDAEVMLANTLSDHKPWVQPPINIEFNVPMFTASGLRIRFLNVEERNMGNYDVT 469

Query: 362 PWVRYITQNGD 394
            WVRY+ Q+GD
Sbjct: 470 RWVRYLCQSGD 480


>UniRef50_Q96CW1 Cluster: AP-2 complex subunit mu-1; n=94;
           Fungi/Metazoa group|Rep: AP-2 complex subunit mu-1 -
           Homo sapiens (Human)
          Length = 435

 Score = 87.8 bits (208), Expect = 1e-16
 Identities = 48/136 (35%), Positives = 70/136 (51%), Gaps = 4/136 (2%)
 Frame = +2

Query: 11  RVEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIKSFP 190
           ++E  +  KS FK    A  +E+ IP P +    +     G  KY   +NAI W IK   
Sbjct: 300 KLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMA 359

Query: 191 GGKEYLMRAHFGLPSVVCEEVDGKPPIQVKFEIPYFTTSGIQVRYLKIIEK----SGYQA 358
           G KE  + A   L     ++   +PPI + FE+P F  SG++VRYLK+ E     S +  
Sbjct: 360 GMKESQISAEIELLPTNDKKKWARPPISMNFEVP-FAPSGLKVRYLKVFEPKLNYSDHDV 418

Query: 359 LPWVRYITQNGDYQLR 406
           + WVRYI ++G Y+ R
Sbjct: 419 IKWVRYIGRSGIYETR 434


>UniRef50_A3LVW0 Cluster: Predicted protein; n=2; Pichia|Rep:
           Predicted protein - Pichia stipitis (Yeast)
          Length = 465

 Score = 87.0 bits (206), Expect = 2e-16
 Identities = 47/147 (31%), Positives = 77/147 (52%), Gaps = 14/147 (9%)
 Frame = +2

Query: 8   ARVEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIKSF 187
           +++ Y I+ KS F  +  A NV+I +P P          + G  K+ PE N I W    F
Sbjct: 318 SKLSYKIRVKSCFPAKIPATNVQIKVPTPKGVLDSYSSNSAGKSKFHPEDNVILWKFNKF 377

Query: 188 PGGKEYLMRAHFGLP------SVVCEEVD--------GKPPIQVKFEIPYFTTSGIQVRY 325
            G +E+++ A   L       S    + +         +PPI++ F I  F++SG+ V++
Sbjct: 378 FGEQEHVLTAEVELADNSHDTSQQMAQTNTTNSILNWSRPPIKLDFVIEMFSSSGLAVKF 437

Query: 326 LKIIEKSGYQALPWVRYITQNGDYQLR 406
           LK+ EKS Y+ + WV+Y TQ+G Y++R
Sbjct: 438 LKVQEKSNYKTVKWVKYSTQSGSYEIR 464


>UniRef50_Q3E8F7 Cluster: Uncharacterized protein At5g46630.2; n=17;
           Viridiplantae|Rep: Uncharacterized protein At5g46630.2 -
           Arabidopsis thaliana (Mouse-ear cress)
          Length = 441

 Score = 86.6 bits (205), Expect = 3e-16
 Identities = 42/109 (38%), Positives = 62/109 (56%), Gaps = 1/109 (0%)
 Frame = +2

Query: 11  RVEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIKSFP 190
           R+E  +K KS F  +  A  V + IPVP       F+ T G  KY P  + + W I+ FP
Sbjct: 305 RMEVNVKVKSVFGAKMFALGVVVKIPVPKQTAKTNFQVTTGRAKYNPSIDCLVWKIRKFP 364

Query: 191 GGKEYLMRAHFGLPSVVCEEVD-GKPPIQVKFEIPYFTTSGIQVRYLKI 334
           G  E  + A   L S + E+    +PPIQ++F++P FT SG++VR+LK+
Sbjct: 365 GQTESTLSAEIELISTMGEKKSWTRPPIQMEFQVPMFTASGLRVRFLKV 413


>UniRef50_P35603 Cluster: AP-2 complex subunit mu; n=23;
           Eukaryota|Rep: AP-2 complex subunit mu - Caenorhabditis
           elegans
          Length = 441

 Score = 85.8 bits (203), Expect = 4e-16
 Identities = 49/138 (35%), Positives = 72/138 (52%), Gaps = 6/138 (4%)
 Frame = +2

Query: 11  RVEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIKSFP 190
           ++E  +  KS FK    A  +E+ IP P +    +     G  KY   +NAI W IK   
Sbjct: 304 KMEVKVVVKSNFKPSLLAQKLEVRIPTPPNTSGVQLICMKGKAKYKAGENAIVWKIKRMA 363

Query: 191 GGKEYLMRAHFGLPSV--VCEEVDGKPPIQVKFEIPYFTTSGIQVRYLKIIEK----SGY 352
           G KE  + A   L S   V ++   +PP+ + FE+P F  SG++VRYLK+ E     S +
Sbjct: 364 GMKESQISAEIDLLSTGNVEKKKWNRPPVSMNFEVP-FAPSGLKVRYLKVFEPKLNYSDH 422

Query: 353 QALPWVRYITQNGDYQLR 406
             + WVRYI ++G Y+ R
Sbjct: 423 DVIKWVRYIGRSGLYETR 440


>UniRef50_Q5AJY3 Cluster: Putative uncharacterized protein; n=1;
           Candida albicans|Rep: Putative uncharacterized protein -
           Candida albicans (Yeast)
          Length = 177

 Score = 84.6 bits (200), Expect = 1e-15
 Identities = 58/125 (46%), Positives = 69/125 (55%), Gaps = 2/125 (1%)
 Frame = -2

Query: 378 MYLTQGKA*Y-PLFSIILR*RT*IPEVVK*GISNFT*IGGF-PSTSSQTTDGKPKWALIK 205
           MYLT G   Y  L S+IL+ RT IP VVK G+  FT IG      S   T GKP  ALI+
Sbjct: 1   MYLTHGYDWYCNLGSLILKYRTWIPSVVKYGMEKFTFIGFLLMMDSGSVTAGKPNSALIE 60

Query: 204 YSLPPGNDLIDHVIAFCSGVYLTLPIVVLNFGESASAGTGIIISTLLAVERLLNCDLALI 25
             LPPGN    H+    SG++ T P    N G SAS+G G+  STLLAV+  L C L + 
Sbjct: 61  NCLPPGNVFNFHIRHDFSGIHFTEPYSGENLGVSASSGIGMTTSTLLAVDFFLICALTVH 120

Query: 24  MYSTR 10
             S R
Sbjct: 121 TISIR 125


>UniRef50_Q1JSZ4 Cluster: Clathrin coat assembly protein, putative;
           n=1; Toxoplasma gondii|Rep: Clathrin coat assembly
           protein, putative - Toxoplasma gondii
          Length = 517

 Score = 83.4 bits (197), Expect = 2e-15
 Identities = 49/142 (34%), Positives = 74/142 (52%), Gaps = 8/142 (5%)
 Frame = +2

Query: 5   EARVEYMIKAKSQFKRRSTANNVEIIIPVPAD--ADSPKF--KTTIGSVKYTPEQNAITW 172
           + + E  +K K+    ++ A  V + IP+P    A S +      + S ++ P +  + W
Sbjct: 375 QTKGELTVKVKADIPEQTYAATVALSIPLPKGIVACSTELLPPVPLQSAEFLPAEKRLVW 434

Query: 173 SIKSFPGGKEYLMRAHFGLPSVVCEEVDGKP---PIQVKFEIPYFTTSGIQVRYLKIIEK 343
           +I+ F GG E +MRA F   S V      +    PI + FEIP F  S +QVRYL+I EK
Sbjct: 435 NIRKFHGGAEMIMRARFTSSSPVTASAAYRKEFGPISMTFEIPMFNVSNLQVRYLRIAEK 494

Query: 344 SGYQA-LPWVRYITQNGDYQLR 406
           +G  +   WVRY+TQ+  Y  R
Sbjct: 495 NGVASPFRWVRYVTQSSSYICR 516


>UniRef50_A2ER69 Cluster: Adaptor complexes medium subunit family
           protein; n=1; Trichomonas vaginalis G3|Rep: Adaptor
           complexes medium subunit family protein - Trichomonas
           vaginalis G3
          Length = 433

 Score = 83.0 bits (196), Expect = 3e-15
 Identities = 40/135 (29%), Positives = 70/135 (51%), Gaps = 3/135 (2%)
 Frame = +2

Query: 11  RVEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIKSFP 190
           ++E  +   S +  + +A  + + IP+P +A   + + + G   +  EQNA+ W I  F 
Sbjct: 297 KIEIRVSVTSNYDMKLSATPLIVKIPMPENASETQIEQSQGKGVFVGEQNAVIWKINGFA 356

Query: 191 GGKEYLMRAHFGLPSVVCEEVDG---KPPIQVKFEIPYFTTSGIQVRYLKIIEKSGYQAL 361
           G  +  +  +    +    E      K PI  +F IP  + SG+ ++YLK++EKS Y   
Sbjct: 357 GKTQADITIYVTCLASTTNESPSLKIKDPISCEFNIPMLSASGLALQYLKVVEKSNYTPD 416

Query: 362 PWVRYITQNGDYQLR 406
            W+RY+TQ G Y++R
Sbjct: 417 KWIRYLTQAGKYEVR 431


>UniRef50_Q09718 Cluster: AP-2 complex subunit mu; n=1;
           Schizosaccharomyces pombe|Rep: AP-2 complex subunit mu -
           Schizosaccharomyces pombe (Fission yeast)
          Length = 446

 Score = 82.6 bits (195), Expect = 4e-15
 Identities = 41/134 (30%), Positives = 71/134 (52%), Gaps = 2/134 (1%)
 Frame = +2

Query: 11  RVEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIKSFP 190
           ++ Y I  ++ +  +  ++++   IPVP +      +   G   Y P +N I W I  F 
Sbjct: 313 KIIYRISIRADYPHK-LSSSLNFRIPVPTNVVKANPRVNRGKAGYEPSENIINWKIPRFL 371

Query: 191 GGKEYLMRAHFGLPSVVCEEVDGKPPIQVKFEIPYFTTSGIQVRYLKIIEKSG--YQALP 364
           G  E +  A   L +   +++  KPPI + F I  FT+SG+ V+YL++ E S   Y+++ 
Sbjct: 372 GETELIFYAEVELSNTTNQQIWAKPPISLDFNILMFTSSGLHVQYLRVSEPSNSKYKSIK 431

Query: 365 WVRYITQNGDYQLR 406
           WVRY T+ G  ++R
Sbjct: 432 WVRYSTRAGTCEIR 445


>UniRef50_Q99186 Cluster: AP-2 complex subunit mu; n=2;
           Saccharomyces cerevisiae|Rep: AP-2 complex subunit mu -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 491

 Score = 80.2 bits (189), Expect = 2e-14
 Identities = 44/135 (32%), Positives = 73/135 (54%), Gaps = 4/135 (2%)
 Frame = +2

Query: 14  VEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIKSFPG 193
           ++Y I  KS F  + +A +V + IPVP      K   + G  K+ PE+NA+ W    + G
Sbjct: 356 IDYRITLKSLFPGKLSAKDVVLHIPVPPSTVDCKISVSNGHCKFVPEENAMIWRFNKYNG 415

Query: 194 GKEYLMRAHFGLPSVVCE---EVDGKPPIQVKFEIPYFTTSGIQVRYLKIIEK-SGYQAL 361
             E  + A     S   +   +   +PPI ++FE+  F+ SG+ VRY  I  K S ++A+
Sbjct: 416 LTENTLSAVTVSTSDTTQLNLQQWTRPPISLEFEVMMFSNSGLVVRYFTISGKDSKHRAV 475

Query: 362 PWVRYITQNGDYQLR 406
            W++YI++ G Y++R
Sbjct: 476 KWIKYISKAGSYEVR 490


>UniRef50_Q7QZ95 Cluster: GLP_567_48751_50055; n=2; Giardia
           intestinalis|Rep: GLP_567_48751_50055 - Giardia lamblia
           ATCC 50803
          Length = 434

 Score = 78.2 bits (184), Expect = 9e-14
 Identities = 39/136 (28%), Positives = 69/136 (50%), Gaps = 4/136 (2%)
 Frame = +2

Query: 11  RVEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIKSFP 190
           R+E ++  +      + A +V + +P+P++        ++G  +   +  A  W IKS  
Sbjct: 300 RMEIVLNLRCGIPSNNVAEHVIVSVPMPSNVSDVTAIESLGKCRLRKDGQAAEWRIKSIT 359

Query: 191 GGKEYLMRAHFGLPSVVCEEVD----GKPPIQVKFEIPYFTTSGIQVRYLKIIEKSGYQA 358
           GG    +     +  V    +D     +PP+ + F+IP +T SGI+VRY++II + GY+ 
Sbjct: 360 GGTTATLSME--VQCVSSSSIDLREWRRPPLAMNFDIPMYTASGIEVRYIRIIAQEGYET 417

Query: 359 LPWVRYITQNGDYQLR 406
             W+ Y T  G YQ+R
Sbjct: 418 EKWLTYKTSAGTYQIR 433


>UniRef50_Q6CUL9 Cluster: Similar to sp|Q99186 Saccharomyces
           cerevisiae YOL062c APM4 AP-2 complex subunit; n=3;
           Saccharomycetales|Rep: Similar to sp|Q99186
           Saccharomyces cerevisiae YOL062c APM4 AP-2 complex
           subunit - Kluyveromyces lactis (Yeast) (Candida
           sphaerica)
          Length = 475

 Score = 77.0 bits (181), Expect = 2e-13
 Identities = 40/136 (29%), Positives = 67/136 (49%), Gaps = 5/136 (3%)
 Frame = +2

Query: 14  VEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIKSFPG 193
           + Y +  +S F    +A +V + IPVP       F  + G  KY   +  + W    + G
Sbjct: 339 LNYKVTLRSLFPSNVSAKDVTVKIPVPPTTIKCDFNVSGGKCKYDAGEKCMVWKYNKYKG 398

Query: 194 GKEYLMRAHFGLPSVVCEEVD----GKPPIQVKFEIPYFTTSGIQVRYLKIIE-KSGYQA 358
             E  +     +P+   +  D     +PPI + FEI  F+ SG+ VR+LK  E +  YQ 
Sbjct: 399 STENTLSGKVAIPATSHDLSDLLRWSRPPISMGFEIVMFSNSGLVVRHLKCQEPQLNYQP 458

Query: 359 LPWVRYITQNGDYQLR 406
           + W++YI+ +G Y++R
Sbjct: 459 VKWIKYISHSGAYEIR 474


>UniRef50_A7ST88 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 432

 Score = 74.9 bits (176), Expect = 8e-13
 Identities = 42/132 (31%), Positives = 63/132 (47%), Gaps = 6/132 (4%)
 Frame = +2

Query: 5   EAR-VEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIG----SVKYTPEQNAIT 169
           EAR +E M+K +      S++NN+ + +PVP   +       +G    S +Y   +  + 
Sbjct: 301 EARYIEVMLKLRCNIPSSSSSNNIIVRVPVPKSTERYILSHDVGHAGHSAEYKTAEKLLL 360

Query: 170 WSIKSFPGGKEYLMRAHFGLPSVVCEEVDGKPPIQVKFEIPYFTTSGIQVRYLKIIEK-S 346
           W +KS  GG E  +     L            P+ + FEIP +  SG+Q+R LK+ EK  
Sbjct: 361 WQVKSIRGGAEVAINIKLKLKDKAKSARKELGPVSLDFEIPMYICSGLQIRSLKVYEKEK 420

Query: 347 GYQALPWVRYIT 382
            Y    WVRYIT
Sbjct: 421 AYHPFRWVRYIT 432


>UniRef50_Q5CWB6 Cluster: Clathrin coat assembly protein AP50; n=2;
           Cryptosporidium|Rep: Clathrin coat assembly protein AP50
           - Cryptosporidium parvum Iowa II
          Length = 548

 Score = 72.5 bits (170), Expect = 4e-12
 Identities = 45/144 (31%), Positives = 71/144 (49%), Gaps = 9/144 (6%)
 Frame = +2

Query: 2   HEARVEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGSV------KYTPEQNA 163
           + ++ +++IK K      S A N+ ++ P+P   ++   +T    +      +Y  +   
Sbjct: 403 NSSKFDFVIKLKVDIPESSFATNLTMLCPLPEKTNTVSLETIHPLIPVQQTSQYDDKNQR 462

Query: 164 ITWSIKSFPGGKEYLMRAHFGLP-SVVCEEVDGK-PPIQVKFEIPYFTTSGIQVRYLKII 337
           I W IK   GG E ++++   L        +  K  P+ + FEIP F  S IQV+YLKI 
Sbjct: 463 IIWKIKKIHGGTEIILKSKICLSFETDLNSIRKKIGPLFLNFEIPMFNLSNIQVKYLKIS 522

Query: 338 EKSGYQ-ALPWVRYITQNGDYQLR 406
           EK G Q    WVRY+TQ+  Y  R
Sbjct: 523 EKYGQQNNYRWVRYVTQSNSYIYR 546


>UniRef50_A0BJZ5 Cluster: Chromosome undetermined scaffold_111,
           whole genome shotgun sequence; n=3;
           Oligohymenophorea|Rep: Chromosome undetermined
           scaffold_111, whole genome shotgun sequence - Paramecium
           tetraurelia
          Length = 439

 Score = 69.3 bits (162), Expect = 4e-11
 Identities = 45/141 (31%), Positives = 70/141 (49%), Gaps = 8/141 (5%)
 Frame = +2

Query: 8   ARVEYMIKAKSQFKRRSTANNVEIIIPVP---ADADSPKFKTT-IGSVKYTPEQNAITWS 175
           +++E  IK K+ F  +  A+   + IP+P   A+A     K   + + +Y   +  + W 
Sbjct: 299 SKIEVTIKLKACFDAKIIASYANVRIPIPKQTANAYPELVKNAQLETAEYDSNKKMVEWQ 358

Query: 176 IKSFPGGKEYLMRAHFGLPSVVCEEVDGKP--PIQVKFEIPYFTTSGIQVRYLKIIEKSG 349
           IK   GG+E  ++    L +        K   PI + FEIP F  S +Q++YL+ IE+ G
Sbjct: 359 IKKLCGGQERSLKIKLTLQATQTAHTARKEIGPIAMNFEIPMFNVSRLQIKYLR-IEERG 417

Query: 350 YQALP--WVRYITQNGDYQLR 406
               P  WVRYITQ+  Y  R
Sbjct: 418 NTTNPHRWVRYITQSSSYVCR 438


>UniRef50_Q9SB50 Cluster: Clathrin coat assembly like protein; n=7;
           Magnoliophyta|Rep: Clathrin coat assembly like protein -
           Arabidopsis thaliana (Mouse-ear cress)
          Length = 451

 Score = 68.5 bits (160), Expect = 7e-11
 Identities = 38/138 (27%), Positives = 65/138 (47%), Gaps = 6/138 (4%)
 Frame = +2

Query: 11  RVEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGSV----KYTPEQNAITWSI 178
           + E +IK +++F     AN + + +P+P       F+   G+      +      + W++
Sbjct: 313 KAEVIIKIRAEFPSDIIANTITVQMPLPNYTSRASFELEPGAAGQRTDFKESNKMLEWNL 372

Query: 179 KSFPGGKEYLMRAHFGLPSVVCEEVDGKP-PIQVKFEIPYFTTSGIQVRYLKIIEKSG-Y 352
           K   GG E+ +RA           +  +  P+ + F IP +  S +QV+YL+I +KS  Y
Sbjct: 373 KKIVGGGEHTLRAKLTFSQEFHGNITKEAGPVSMTFTIPMYNVSKLQVKYLQIAKKSSSY 432

Query: 353 QALPWVRYITQNGDYQLR 406
               WVRY+TQ   Y  R
Sbjct: 433 NPYRWVRYVTQANSYVAR 450


>UniRef50_Q4DZV1 Cluster: Clathrin coat assembly protein, putative;
           n=2; Trypanosoma cruzi|Rep: Clathrin coat assembly
           protein, putative - Trypanosoma cruzi
          Length = 416

 Score = 68.1 bits (159), Expect = 1e-10
 Identities = 42/139 (30%), Positives = 66/139 (47%), Gaps = 5/139 (3%)
 Frame = +2

Query: 5   EARVEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIKS 184
           + R E     K   K     ++VEI IP P +          G V++   Q+A+ W + +
Sbjct: 277 KTRTEIDFGLKCDIKEGMRCDDVEIRIPCPENTADVNLSVARGRVQFDGVQHAVIWKLPT 336

Query: 185 F-PGGKEYLMRAHFGL--PSV-VCEEVDGKPPIQVKFEIPYFTTSGIQVRYLKIIEK-SG 349
                +E L+ A   L  P++   E+V  +PPI++ F  P    SG +V+ L++ E    
Sbjct: 337 LSQNDEELLLTAEIVLLAPTIATSEQVWSRPPIKISFTTPSHVLSGFRVKELRVEEPLLR 396

Query: 350 YQALPWVRYITQNGDYQLR 406
           Y A  WVRY+T  G Y+ R
Sbjct: 397 YSASKWVRYLTTTGQYEWR 415


>UniRef50_Q7QT00 Cluster: GLP_384_5522_6868; n=2; Giardia
           intestinalis|Rep: GLP_384_5522_6868 - Giardia lamblia
           ATCC 50803
          Length = 448

 Score = 65.3 bits (152), Expect = 7e-10
 Identities = 32/106 (30%), Positives = 58/106 (54%), Gaps = 5/106 (4%)
 Frame = +2

Query: 17  EYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIKSFPGG 196
           EY +K ++ +  R  +  + I +PV  + DSPK +T  G +KY P +  + W ++S PG 
Sbjct: 314 EYHLKLETLYPSRIISKQIVISVPVMMNIDSPKLQTRRGIMKYCPHEQVVKWILESLPGK 373

Query: 197 KEYLMRAHFGLPS-----VVCEEVDGKPPIQVKFEIPYFTTSGIQV 319
           + +    +FG+PS     + C+    + PI +++ IPY   SG+ +
Sbjct: 374 QIFKALLNFGVPSRHKDQLGCDATSLR-PIVIEYTIPYHHISGLNI 418


>UniRef50_A5JZZ1 Cluster: Clathrin coat assembly protein AP50,
           putative; n=2; Plasmodium|Rep: Clathrin coat assembly
           protein AP50, putative - Plasmodium vivax
          Length = 611

 Score = 64.9 bits (151), Expect = 9e-10
 Identities = 24/49 (48%), Positives = 38/49 (77%)
 Frame = +2

Query: 260 KPPIQVKFEIPYFTTSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLR 406
           K PI + F+IP FT+SG+ +RYLK+ EKS Y+ + W++Y+T++G YQ +
Sbjct: 563 KMPITLSFKIPMFTSSGMYIRYLKVFEKSNYKIIKWIKYLTESGIYQYK 611


>UniRef50_UPI0000583F86 Cluster: PREDICTED: similar to MGC81080
           protein; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to MGC81080 protein -
           Strongylocentrotus purpuratus
          Length = 436

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 37/134 (27%), Positives = 66/134 (49%), Gaps = 3/134 (2%)
 Frame = +2

Query: 14  VEYMIKAKSQFKRRSTANNVEIIIPVP-ADAD-SPKFKTTIGSVKYTPEQNAITWSIKSF 187
           VE  +       +R  A NV++ +P+P A  D SP   +   +++Y     +  W IK  
Sbjct: 301 VEVELHITCHIDQRHHAVNVKLNLPLPKATTDVSPSLPSQTHTMEYKRGDRSAVWCIKKM 360

Query: 188 PGGKEYLMRAHFGLPSVVCEEVDGKPPIQVKFEIPYFTTSGIQVRYLKIIEK-SGYQALP 364
            GG ++  +    L  +    +    P  ++FE+  FT+S +Q+R+LK+ ++ + Y    
Sbjct: 361 MGGSKHTAKLRIHLDHLSSSTLIEIGPASLEFELKDFTSSKLQIRFLKVFDRHNSYVPFR 420

Query: 365 WVRYITQNGDYQLR 406
           WVRY T +  Y +R
Sbjct: 421 WVRYATLSDSYVIR 434


>UniRef50_Q7RAH7 Cluster: Clathrin coat assembly protein ap50; n=5;
           Plasmodium (Vinckeia)|Rep: Clathrin coat assembly
           protein ap50 - Plasmodium yoelii yoelii
          Length = 601

 Score = 64.1 bits (149), Expect = 2e-09
 Identities = 46/164 (28%), Positives = 80/164 (48%), Gaps = 32/164 (19%)
 Frame = +2

Query: 11  RVEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFK-TTIGSVKYTPEQNAITWSIKSF 187
           + EY I  +S +     A +V I IP+   +++      +IG  ++   +N ITW I  F
Sbjct: 438 KFEYKITIRSNYSGSMNATDVVIKIPIYKFSENVHVVYKSIGKTEFNNIENVITWKISKF 497

Query: 188 PGGKEYLMRAHFGLPSV--------VCEEVDGKPPI-----------QVKF--------- 283
           P   E+ ++ +  L +           ++VDG+  +            VKF         
Sbjct: 498 PNLCEHTIKIYLTLENQNQIYSNMNNTQKVDGQSKVVLHVNTVKNMNTVKFLNTYKMPIT 557

Query: 284 ---EIPYFTTSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLR 406
              +IP FT+SG+ +RYLK+ EKS Y+ + W++Y+T++G YQ +
Sbjct: 558 LNFKIPMFTSSGMFIRYLKVYEKSNYKIIKWIKYLTESGAYQYK 601


>UniRef50_Q4Q1B6 Cluster: Clathrin coat assembly protein-like
           protein; n=3; Leishmania|Rep: Clathrin coat assembly
           protein-like protein - Leishmania major
          Length = 438

 Score = 63.7 bits (148), Expect = 2e-09
 Identities = 37/137 (27%), Positives = 62/137 (45%), Gaps = 3/137 (2%)
 Frame = +2

Query: 5   EARVEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIKS 184
           + R E     +S       A +V++ +  P +  + + K   G  KY P  +AI W +  
Sbjct: 301 KTRTEVEFTLRSDTPAGRVAKDVQVSVACPDNTATAEVKVGHGKAKYDPVSHAIVWKLPE 360

Query: 185 FPGGKEYLMRAHFG--LPSVVCEEVDGKPPIQVKFEIPYFTTSGIQVRYLKIIEKS-GYQ 355
              G+E    A      P+   E +  KPPI++ F+    + +G+++  L + E +  Y 
Sbjct: 361 VKSGEEIAFFAEIRQITPTENTELLWTKPPIRIAFQCVSLSLTGLRINELVVKEPTLMYT 420

Query: 356 ALPWVRYITQNGDYQLR 406
           A  W+RY    GDYQ R
Sbjct: 421 ASKWIRYTVMAGDYQCR 437


>UniRef50_Q759G1 Cluster: ADR315Wp; n=1; Eremothecium gossypii|Rep:
           ADR315Wp - Ashbya gossypii (Yeast) (Eremothecium
           gossypii)
          Length = 492

 Score = 61.7 bits (143), Expect = 8e-09
 Identities = 37/109 (33%), Positives = 56/109 (51%), Gaps = 5/109 (4%)
 Frame = +2

Query: 2   HEARVEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIK 181
           +E  +EY I  +S F  + +A +VE+ IP P    S K   + G  K+ PE+NAI W I 
Sbjct: 315 NERSIEYRITLQSLFPTKLSAKDVELYIPAPPYTISAKVNVSCGKCKFVPEENAIIWKIH 374

Query: 182 SFPGGKEYLMRA-----HFGLPSVVCEEVDGKPPIQVKFEIPYFTTSGI 313
            F G  E  + A       G  + V ++   +PPI +K EI  F+T+ +
Sbjct: 375 KFHGLTENTLSAVTIADEQGHYAQVLDQWP-RPPISMKLEIMMFSTAAL 422


>UniRef50_Q4SPT3 Cluster: Chromosome 7 SCAF14536, whole genome
           shotgun sequence; n=9; Euteleostomi|Rep: Chromosome 7
           SCAF14536, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 449

 Score = 57.6 bits (133), Expect = 1e-07
 Identities = 38/141 (26%), Positives = 65/141 (46%), Gaps = 9/141 (6%)
 Frame = +2

Query: 11  RVEYMIKAKSQFKRRSTANNVEIIIPVPADADS--PKFKTTIGSVKYTPEQNAITWSIKS 184
           R+   +K +     +S A +V   IPVP  + S   +  +   S +  P+  A+ W I  
Sbjct: 308 RLLMYLKLRCDLPPKSAAIHVCATIPVPKGSLSLSQELSSPDQSAELKPQSRAVQWQIPR 367

Query: 185 FPGGKEY--LMRAH-----FGLPSVVCEEVDGKPPIQVKFEIPYFTTSGIQVRYLKIIEK 343
           FPGG +   L +         +P +    +    P  + FE+P FT +G+Q+R+L++   
Sbjct: 368 FPGGTQLSALFKVTTESEPLEVPGLSSASMLEVGPFALSFELPKFTVTGLQIRFLRLSPI 427

Query: 344 SGYQALPWVRYITQNGDYQLR 406
               +  WVRY T +  Y +R
Sbjct: 428 QPSPSQRWVRYTTLSDSYTIR 448


>UniRef50_A7AS46 Cluster: Clathrin coat adaptor subunit, putative;
           n=1; Babesia bovis|Rep: Clathrin coat adaptor subunit,
           putative - Babesia bovis
          Length = 474

 Score = 57.6 bits (133), Expect = 1e-07
 Identities = 32/129 (24%), Positives = 61/129 (47%)
 Frame = +2

Query: 20  YMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIKSFPGGK 199
           Y I  ++ F +++ A NV + IP+P +A   +  +  G  +    +N + W +    G  
Sbjct: 342 YHISMETNFPKKTFATNVGMDIPLPINASHVEIISNAGQCQIKIAENMVHWHLGKVYGQT 401

Query: 200 EYLMRAHFGLPSVVCEEVDGKPPIQVKFEIPYFTTSGIQVRYLKIIEKSGYQALPWVRYI 379
              M  H  L   +        P+ + F++P ++ SG+ +R +K I  + Y+ +  V Y 
Sbjct: 402 ILSMEFHCRLTKSITGVSTHLSPLALHFDLPNYSFSGLYIRDVK-ITNTQYKTIKSVSYT 460

Query: 380 TQNGDYQLR 406
           T NG+Y  +
Sbjct: 461 TVNGEYHYK 469


>UniRef50_A4S949 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
           Predicted protein - Ostreococcus lucimarinus CCE9901
          Length = 481

 Score = 56.8 bits (131), Expect = 2e-07
 Identities = 40/148 (27%), Positives = 67/148 (45%), Gaps = 16/148 (10%)
 Frame = +2

Query: 11  RVEYMIKAKSQFKRRSTANNVEIIIPVP-----ADADSPKFKT-TIGSVKYTPEQNAITW 172
           +V   +K  + F  + T     + +P+P     A A  PK  T +   V Y   +  I W
Sbjct: 333 KVGIELKLYADFNAKHTCTGCIVTLPIPKGAIGATARLPKHVTASTQHVMYDAAEKQIVW 392

Query: 173 SIKSFPGGKEYLMRAHFGLPSVVCEEVDGK-PPIQVKFEIPYFTTSGIQVRYLKIIEKSG 349
             K  PGG ++       L S     V  +  P+ + F+IP F+ S + VRYL+++  S 
Sbjct: 393 QFKKLPGGSDHECSVQISLQSERIPNVRREIGPLSLTFQIPTFSASDLAVRYLQVVGSSN 452

Query: 350 ---YQALP------WVRYITQNGDYQLR 406
              ++  P      W+RY+T++  Y +R
Sbjct: 453 EPRHRDDPPRNPHRWIRYMTKSSSYVVR 480


>UniRef50_A7AUL5 Cluster: Clathrin coat assembly protein, putative;
           n=1; Babesia bovis|Rep: Clathrin coat assembly protein,
           putative - Babesia bovis
          Length = 435

 Score = 55.2 bits (127), Expect = 7e-07
 Identities = 28/93 (30%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
 Frame = +2

Query: 134 SVKYTPEQNAITWSIKSFPGGKEYLMRAHFGLPSVVCEEVDGK-PPIQVKFEIPYFTTSG 310
           + +Y P+  +I+W ++ + G   Y +RA   L S   +    +  P+ + FE P F+ S 
Sbjct: 342 ATEYRPKDQSISWEVRKYRGCTGYTLRASVNLGSHGSKISKREFGPLNLTFEAPLFSVSN 401

Query: 311 IQVRYLKIIE-KSGYQALPWVRYITQNGDYQLR 406
           ++VRYL +++  S   +  WVRY+T +  Y  R
Sbjct: 402 VRVRYLGVLQPPSSGPSYRWVRYVTSSQSYIYR 434


>UniRef50_A5K4K8 Cluster: Adapter-related protein complex 4 mu 1
           subunit, putative; n=6; Plasmodium|Rep: Adapter-related
           protein complex 4 mu 1 subunit, putative - Plasmodium
           vivax
          Length = 496

 Score = 54.8 bits (126), Expect = 1e-06
 Identities = 35/100 (35%), Positives = 51/100 (51%), Gaps = 9/100 (9%)
 Frame = +2

Query: 134 SVKYTPEQNAITWSIKSF-------PGGKEYLMRAHFGL-PSVVCEEVDGKPPIQVKFEI 289
           S +Y   ++ + W+IK F       PG  E+ +R+   L P     + D  P I + FEI
Sbjct: 396 SAQYIANEHRLLWTIKKFKVGLFTPPGEHEHSIRSKITLSPGYTFAKRDFGP-IYILFEI 454

Query: 290 PYFTTSGIQVRYLKIIEK-SGYQALPWVRYITQNGDYQLR 406
           P F  S ++++YL+IIE         WVRYITQ+  Y  R
Sbjct: 455 PMFNLSKLRIKYLRIIESYKSSNTHRWVRYITQSSSYVYR 494


>UniRef50_Q550G8 Cluster: Clathrin-adaptor medium chain apm 4; n=3;
           Dictyostelium discoideum|Rep: Clathrin-adaptor medium
           chain apm 4 - Dictyostelium discoideum AX4
          Length = 530

 Score = 53.6 bits (123), Expect = 2e-06
 Identities = 41/159 (25%), Positives = 67/159 (42%), Gaps = 25/159 (15%)
 Frame = +2

Query: 11  RVEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGS----VKY---TPEQNAIT 169
           R + ++  +S F  +   N + + IPVP    S       GS    V+Y   T   N + 
Sbjct: 372 RFDLVVTIRSNFSNKVVPNFIFVSIPVPKSTKSLTHSLDYGSQNQKVEYKQSTQAGNLVF 431

Query: 170 WSIKSFPGGKEYLMRAHFGLPSVVCEEVDGKP------------------PIQVKFEIPY 295
           WSIK   GG E ++R    +        +                     PI ++F IP 
Sbjct: 432 WSIKKLRGGMETILRIQIHVDGATSSSSNNNQQQQQPQIDVGSTLRKEIGPIGLEFSIPQ 491

Query: 296 FTTSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLRTN 412
           F+ S +Q+++LK++  S    + W+RYIT +  +  R N
Sbjct: 492 FSCSTLQIKFLKML-GSNISPIRWIRYITDSKSFVSRIN 529


>UniRef50_A7TLM0 Cluster: Putative uncharacterized protein; n=1;
           Vanderwaltozyma polyspora DSM 70294|Rep: Putative
           uncharacterized protein - Vanderwaltozyma polyspora DSM
           70294
          Length = 541

 Score = 53.2 bits (122), Expect = 3e-06
 Identities = 24/43 (55%), Positives = 30/43 (69%), Gaps = 1/43 (2%)
 Frame = +2

Query: 269 IQVKFEIPYFTTSGIQVRYLKIIEKS-GYQALPWVRYITQNGD 394
           + +KFE+PY T SG++V YLKI E    YQ+ PWVRY T N D
Sbjct: 493 LTMKFEVPYSTCSGLKVEYLKIEENQVNYQSFPWVRYKTINDD 535


>UniRef50_Q6CIM6 Cluster: Kluyveromyces lactis strain NRRL Y-1140
           chromosome F of strain NRRL Y- 1140 of Kluyveromyces
           lactis; n=1; Kluyveromyces lactis|Rep: Kluyveromyces
           lactis strain NRRL Y-1140 chromosome F of strain NRRL Y-
           1140 of Kluyveromyces lactis - Kluyveromyces lactis
           (Yeast) (Candida sphaerica)
          Length = 507

 Score = 52.4 bits (120), Expect = 5e-06
 Identities = 25/49 (51%), Positives = 32/49 (65%), Gaps = 1/49 (2%)
 Frame = +2

Query: 245 EEVDGKPPIQVKFEIPYFTTSGIQVRYLKIIE-KSGYQALPWVRYITQN 388
           E+VD    I + FEIPY+  SG++V Y KI E +  YQ+ PWVRY T N
Sbjct: 449 EDVDKFALIAMSFEIPYYAVSGLKVEYFKIEEPQLNYQSFPWVRYKTVN 497


>UniRef50_UPI0000DD86A9 Cluster: PREDICTED: similar to AP-1 complex
           subunit mu-2 (Adaptor-related protein complex 1 mu-2
           subunit) (Mu-adaptin 2) (Adaptor protein complex AP-1
           mu-2 subunit) (Golgi adaptor HA1/AP1 adaptin mu-2
           subunit) (Clathrin assembly protein assembly protein
           complex 1 medi...; n=1; Homo sapiens|Rep: PREDICTED:
           similar to AP-1 complex subunit mu-2 (Adaptor-related
           protein complex 1 mu-2 subunit) (Mu-adaptin 2) (Adaptor
           protein complex AP-1 mu-2 subunit) (Golgi adaptor
           HA1/AP1 adaptin mu-2 subunit) (Clathrin assembly protein
           assembly protein complex 1 medi... - Homo sapiens
          Length = 50

 Score = 41.5 bits (93), Expect(2) = 9e-06
 Identities = 18/25 (72%), Positives = 22/25 (88%)
 Frame = +2

Query: 245 EEVDGKPPIQVKFEIPYFTTSGIQV 319
           +EV+G+P I+VKFEIPY T SGIQV
Sbjct: 26  KEVEGRPLIRVKFEIPYSTVSGIQV 50



 Score = 29.9 bits (64), Expect(2) = 9e-06
 Identities = 11/20 (55%), Positives = 15/20 (75%)
 Frame = +2

Query: 83  IPVPADADSPKFKTTIGSVK 142
           +P+P DADSP  KT++ S K
Sbjct: 3   VPIPNDADSPHLKTSVCSAK 22


>UniRef50_Q75DH8 Cluster: ABR047Wp; n=1; Eremothecium gossypii|Rep:
           ABR047Wp - Ashbya gossypii (Yeast) (Eremothecium
           gossypii)
          Length = 498

 Score = 49.2 bits (112), Expect = 5e-05
 Identities = 20/41 (48%), Positives = 31/41 (75%), Gaps = 1/41 (2%)
 Frame = +2

Query: 269 IQVKFEIPYFTTSGIQVRYLKIIE-KSGYQALPWVRYITQN 388
           ++V FE+PY T SG++V +LKI+E +  YQ+ PW+RY + N
Sbjct: 450 LRVDFEVPYHTISGLKVEFLKILEPQLQYQSFPWIRYKSTN 490


>UniRef50_P38700 Cluster: Adaptin medium chain homolog APM2; n=3;
           Saccharomycetales|Rep: Adaptin medium chain homolog APM2
           - Saccharomyces cerevisiae (Baker's yeast)
          Length = 605

 Score = 48.0 bits (109), Expect = 1e-04
 Identities = 21/39 (53%), Positives = 28/39 (71%), Gaps = 1/39 (2%)
 Frame = +2

Query: 269 IQVKFEIPYFTTSGIQVRYLKIIE-KSGYQALPWVRYIT 382
           + + FEIPY T SG++V YLK+ E +  YQ+ PWVRY T
Sbjct: 557 VNIDFEIPYCTCSGLKVEYLKVEEPQLQYQSFPWVRYKT 595


>UniRef50_A5DHF6 Cluster: Putative uncharacterized protein; n=1;
           Pichia guilliermondii|Rep: Putative uncharacterized
           protein - Pichia guilliermondii (Yeast) (Candida
           guilliermondii)
          Length = 620

 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 26/85 (30%), Positives = 44/85 (51%), Gaps = 8/85 (9%)
 Frame = +2

Query: 5   EARVEYMIKAKSQFKRRSTANNVEIIIPVPADADSP-------KFKTTIGSVKYTPEQNA 163
           E  V+ M +  + FK+R  ANN++I++P+     SP       K+K  +G V Y  + + 
Sbjct: 405 EKTVQVMCELSTHFKKRLRANNIQIVLPIDPHIFSPLASNPDFKYKAQLGDVSYKIDSSL 464

Query: 164 ITWSIKSFPGGKEYL-MRAHFGLPS 235
           + W+I+S  G +  + M A   L S
Sbjct: 465 LLWNIESLVGSQSSVKMMAQLNLDS 489



 Score = 41.9 bits (94), Expect = 0.007
 Identities = 17/41 (41%), Positives = 27/41 (65%), Gaps = 1/41 (2%)
 Frame = +2

Query: 269 IQVKFEIPYFTTSGIQVRYLKIIEKS-GYQALPWVRYITQN 388
           I VKF IP  +  G+++ Y+K+ E+   Y   PW+RY+TQ+
Sbjct: 553 INVKFTIPMLSYLGLKITYVKVEEEQMKYTCFPWIRYLTQS 593


>UniRef50_O00189 Cluster: AP-4 complex subunit mu-1; n=34;
           Eutheria|Rep: AP-4 complex subunit mu-1 - Homo sapiens
           (Human)
          Length = 453

 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 35/143 (24%), Positives = 62/143 (43%), Gaps = 11/143 (7%)
 Frame = +2

Query: 11  RVEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIKSFP 190
           R++  +K +     +S A NV + +P+P    S   + +    K    + A+ W +    
Sbjct: 310 RLQVYLKLRCDLLSKSQALNVRLHLPLPRGVVSLSQELSSPEQKAELAEGALRWDLPRVQ 369

Query: 191 GGKEYLMRAHFGLPSVVCEEVDG-----KP----PIQVKFEIPYFTTSGIQVRYLKIIEK 343
           GG +        +P        G      P    P  + FE+P  T SG+QVR+L++  +
Sbjct: 370 GGSQLSGLFQMDVPGPPGPPSHGLSTSASPLGLGPASLSFELPRHTCSGLQVRFLRLAFR 429

Query: 344 SGYQALP--WVRYITQNGDYQLR 406
               A P  WVR+++ +  Y +R
Sbjct: 430 PCGNANPHKWVRHLSHSDAYVIR 452


>UniRef50_A5DV27 Cluster: Putative uncharacterized protein; n=1;
           Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
           uncharacterized protein - Lodderomyces elongisporus
           (Yeast) (Saccharomyces elongisporus)
          Length = 761

 Score = 44.4 bits (100), Expect = 0.001
 Identities = 18/43 (41%), Positives = 30/43 (69%), Gaps = 1/43 (2%)
 Frame = +2

Query: 269 IQVKFEIPYFTTSGIQVRYLKIIEKS-GYQALPWVRYITQNGD 394
           IQ+ F+IP +T SG+++ YL + E+   Y   PW+RY+T++ D
Sbjct: 687 IQMTFKIPMYTYSGLKLTYLSVEEEQMKYPCFPWIRYLTKSVD 729


>UniRef50_Q5ACY9 Cluster: Potential clathrin-associated protein AP-1
           complex component; n=2; Saccharomycetales|Rep: Potential
           clathrin-associated protein AP-1 complex component -
           Candida albicans (Yeast)
          Length = 669

 Score = 42.3 bits (95), Expect = 0.005
 Identities = 18/44 (40%), Positives = 30/44 (68%), Gaps = 1/44 (2%)
 Frame = +2

Query: 269 IQVKFEIPYFTTSGIQVRYLKIIEKS-GYQALPWVRYITQNGDY 397
           I+V F++P  T SG+++ YL + E+   Y   PWVRY+T++ D+
Sbjct: 595 IKVHFKLPMVTYSGLKLSYLSVEEEQMKYPCFPWVRYLTKSIDH 638


>UniRef50_Q6BIP8 Cluster: Similar to CA4819|IPF1194 Candida albicans
           IPF1194 Similar to clathrin coat proteins; n=1;
           Debaryomyces hansenii|Rep: Similar to CA4819|IPF1194
           Candida albicans IPF1194 Similar to clathrin coat
           proteins - Debaryomyces hansenii (Yeast) (Torulaspora
           hansenii)
          Length = 688

 Score = 41.9 bits (94), Expect = 0.007
 Identities = 17/41 (41%), Positives = 27/41 (65%), Gaps = 1/41 (2%)
 Frame = +2

Query: 269 IQVKFEIPYFTTSGIQVRYLKIIEKS-GYQALPWVRYITQN 388
           ++  F IP  + SG+++ YLK+ E+   Y   PWVRYIT++
Sbjct: 613 VKCSFNIPMLSYSGLKLTYLKVAEEQMKYTCFPWVRYITES 653


>UniRef50_Q8SSH2 Cluster: CLATHRIN COAT ASSEMBLY PROTEIN; n=1;
           Encephalitozoon cuniculi|Rep: CLATHRIN COAT ASSEMBLY
           PROTEIN - Encephalitozoon cuniculi
          Length = 336

 Score = 41.1 bits (92), Expect = 0.013
 Identities = 30/112 (26%), Positives = 45/112 (40%)
 Frame = +2

Query: 71  VEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIKSFPGGKEYLMRAHFGLPSVVCEE 250
           +EI  P+P  A        +G   Y PE N + W+       KE + R          E+
Sbjct: 231 LEICFPIPKMASKVVKSHRLGRSAYDPEDNLLRWTFT-----KEVVKRERIDYRVEEFEK 285

Query: 251 VDGKPPIQVKFEIPYFTTSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLR 406
            +   PI V F I  +    I++   + I   G     WVRY   +G Y++R
Sbjct: 286 SEDLRPIVVNFHIKEWGDPKIRIEKAECIGSPG--VCFWVRYSMSSGRYEIR 335


>UniRef50_A2DA54 Cluster: Adaptor complexes medium subunit family
           protein; n=2; Trichomonas vaginalis G3|Rep: Adaptor
           complexes medium subunit family protein - Trichomonas
           vaginalis G3
          Length = 407

 Score = 37.9 bits (84), Expect = 0.12
 Identities = 29/130 (22%), Positives = 51/130 (39%), Gaps = 1/130 (0%)
 Frame = +2

Query: 14  VEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIKSFPG 193
           V + I  K           +EI    P    +P    + G   Y      + W+I+S+  
Sbjct: 275 VSFDIAMKPDAALPKNVEEIEIRFAFPPGVGTPSLVASDGRASYESATRDVVWTIQSYGK 334

Query: 194 GKEYLMRAHFGLPSVVCEEVDGK-PPIQVKFEIPYFTTSGIQVRYLKIIEKSGYQALPWV 370
            +  ++R      S    ++ G+ P +  +F     T SG ++  L  +E+  Y     V
Sbjct: 335 KEPAVLRGSASTESNF--DLGGRYPMVGARFIYVGQTASGFKIEKLD-LERVDYTPFRGV 391

Query: 371 RYITQNGDYQ 400
           +YI Q G Y+
Sbjct: 392 KYIIQAGSYE 401


>UniRef50_A5DI41 Cluster: Putative uncharacterized protein; n=1;
           Pichia guilliermondii|Rep: Putative uncharacterized
           protein - Pichia guilliermondii (Yeast) (Candida
           guilliermondii)
          Length = 486

 Score = 37.1 bits (82), Expect = 0.20
 Identities = 30/97 (30%), Positives = 44/97 (45%), Gaps = 12/97 (12%)
 Frame = +2

Query: 158 NAITWSIKSFPGGKEYLMRAHFGL--PSVVCEEVDG-KPP-----IQVKFEIPYFTTSGI 313
           N   W+I+S   G   + R   G   P    EE    KPP     +++ +       SG+
Sbjct: 389 NTGVWNIRSLNAGVPCIFRGSIGKRNPDEDNEETKSEKPPTFPVYLKLSYTAKGAVPSGL 448

Query: 314 QVRYLKIIEKSGYQ--ALPW--VRYITQNGDYQLRTN 412
           +V  LKI+   G      P+  V+YIT  GDY +RT+
Sbjct: 449 KVESLKIVSSKGLSDSVKPYKGVKYITSTGDYIVRTH 485


>UniRef50_Q4N810 Cluster: Adaptin medium chain, putative; n=2;
           Theileria|Rep: Adaptin medium chain, putative -
           Theileria parva
          Length = 493

 Score = 36.7 bits (81), Expect = 0.27
 Identities = 28/131 (21%), Positives = 53/131 (40%), Gaps = 3/131 (2%)
 Frame = +2

Query: 14  VEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKT--TIGSVKYTPEQNAITWSIKSF 187
           + Y I     F +   A  V + IP+P         T  T  ++      + +TW+ +  
Sbjct: 357 INYSISLSPTFSKAIIAQKVCVKIPIPKTTKEIVSGTISTGTTMDVNLSHHFVTWNFRKL 416

Query: 188 PGGKEYLMRAHFGLPSV-VCEEVDGKPPIQVKFEIPYFTTSGIQVRYLKIIEKSGYQALP 364
            G   +L+     L +      +   P I + F IP+F+ SG+ +  L  +  +  +   
Sbjct: 417 QGETTFLLTFTAALTTDRFGNSLQSLPSISLGFHIPWFSASGLYLSSLD-LSNTKSKVSK 475

Query: 365 WVRYITQNGDY 397
            + Y+T+ G Y
Sbjct: 476 NINYVTKGGLY 486


>UniRef50_Q5BY00 Cluster: SJCHGC04843 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC04843 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 420

 Score = 33.5 bits (73), Expect = 2.5
 Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 7/96 (7%)
 Frame = +2

Query: 119 KTTIGSVKYTPEQNAITWSIKSFPGGKEYLMRAHFGLPSVVCEEVDGKPP-------IQV 277
           + +IG  KY     AI W I   P   E   R H    ++V    D  P         Q+
Sbjct: 280 EASIGVAKYEHLYKAIVWRIPRVPEKSEASFRPHLLTCNLVLAPHDTVPEWEALIPYCQI 339

Query: 278 KFEIPYFTTSGIQVRYLKIIEKSGYQALPWVRYITQ 385
           ++ +P  T SG  VR +  +E +G     +V+Y+T+
Sbjct: 340 EYTMPSSTVSGATVRSIS-VEHTG-NVEKFVKYLTK 373


>UniRef50_Q8WXE9 Cluster: Stonin-2; n=26; Tetrapoda|Rep: Stonin-2 -
            Homo sapiens (Human)
          Length = 905

 Score = 33.5 bits (73), Expect = 2.5
 Identities = 26/96 (27%), Positives = 41/96 (42%), Gaps = 7/96 (7%)
 Frame = +2

Query: 110  PKFKTTIGSVKYTPEQNAITWSIKSFP-----GGKEYLMRAHFGLPSVVCEEVDGK--PP 268
            P  + T+G+ KY    N+I W I   P      G  +    H  L S    EV  +    
Sbjct: 773  PVMRVTLGTAKYEHAFNSIVWRINRLPDKNSASGHPHCFFCHLELGS--DREVPSRFANH 830

Query: 269  IQVKFEIPYFTTSGIQVRYLKIIEKSGYQALPWVRY 376
            + V+F +P  + S   VR + + +K+  +   WV Y
Sbjct: 831  VNVEFSMPTTSASKASVRSISVEDKTDVR--KWVNY 864


>UniRef50_A2E9B8 Cluster: Adaptor complexes medium subunit family
           protein; n=1; Trichomonas vaginalis G3|Rep: Adaptor
           complexes medium subunit family protein - Trichomonas
           vaginalis G3
          Length = 395

 Score = 33.1 bits (72), Expect = 3.3
 Identities = 27/114 (23%), Positives = 50/114 (43%)
 Frame = +2

Query: 56  STANNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIKSFPGGKEYLMRAHFGLPS 235
           S+  N++I   +P     P      GS+KY   QN + WS+++    KE L  +      
Sbjct: 280 SSIKNIQISFNLPKGFHQPSCAAGTGSMKYLKGQNMLIWSLEA-TDQKEILSLSGSCSID 338

Query: 236 VVCEEVDGKPPIQVKFEIPYFTTSGIQVRYLKIIEKSGYQALPWVRYITQNGDY 397
               +   + PI V F++   + SG ++  +  I  +  +    ++Y T+ G Y
Sbjct: 339 EGINKNSCEIPIFVDFKLEDTSISGFKIEEIDPI--NNVKCNKVIKYQTRAGRY 390


>UniRef50_Q552M0 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 350

 Score = 32.7 bits (71), Expect = 4.4
 Identities = 19/53 (35%), Positives = 31/53 (58%), Gaps = 2/53 (3%)
 Frame = -1

Query: 364 RQSLIPTLLNNF--KITNLNSRSCEIRYFKFYLNRWFSIYLFTNYRWQTKVGP 212
           +  +I   +NN   KIT+L+S +C  ++F  Y N++ S YL+ N R Q  + P
Sbjct: 220 KNDIIQLTINNQSPKITHLSSVNC--KFFNGYDNQFNSTYLYYNIRNQVSLAP 270


>UniRef50_Q9Y6Q2 Cluster: Stonin-1; n=51; Tetrapoda|Rep: Stonin-1 -
           Homo sapiens (Human)
          Length = 735

 Score = 32.7 bits (71), Expect = 4.4
 Identities = 23/80 (28%), Positives = 33/80 (41%), Gaps = 5/80 (6%)
 Frame = +2

Query: 110 PKFKTTIGSVKYTPEQNAITWSIKSFPGGKEYLMRAH---FGLPSVVCEEV--DGKPPIQ 274
           P  + T+GS KY     A+ W I   P     L   H   + L     +E+  D  P   
Sbjct: 613 PVIQVTVGSAKYESAYQAVVWKIDRLPDKNSSLDHPHCLSYKLELGSDQEIPSDWYPFAT 672

Query: 275 VKFEIPYFTTSGIQVRYLKI 334
           V+F +P    S  +VR L +
Sbjct: 673 VQFSVPDTCASRTEVRSLGV 692


>UniRef50_Q93Y22 Cluster: Coatomer subunit delta; n=24;
           Eukaryota|Rep: Coatomer subunit delta - Arabidopsis
           thaliana (Mouse-ear cress)
          Length = 527

 Score = 32.7 bits (71), Expect = 4.4
 Identities = 13/37 (35%), Positives = 21/37 (56%)
 Frame = +2

Query: 68  NVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSI 178
           NV I +P+PA  ++P  +   G  +Y P  + + WSI
Sbjct: 419 NVIISVPLPALREAPSVRQCDGEWRYDPRNSVLEWSI 455


>UniRef50_Q0U9R8 Cluster: Putative uncharacterized protein; n=1;
            Phaeosphaeria nodorum|Rep: Putative uncharacterized
            protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 1289

 Score = 32.3 bits (70), Expect = 5.8
 Identities = 15/43 (34%), Positives = 23/43 (53%)
 Frame = +2

Query: 56   STANNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIKS 184
            ST   V++++P P    S  F T IGS+ YT  +   + S+ S
Sbjct: 1111 STFTVVQVVVPTPPPVLSTSFTTFIGSIGYTTTRTITSGSVLS 1153


>UniRef50_Q3T8J9 Cluster: GON-4-like protein; n=45; Eutheria|Rep:
            GON-4-like protein - Homo sapiens (Human)
          Length = 2241

 Score = 32.3 bits (70), Expect = 5.8
 Identities = 15/51 (29%), Positives = 26/51 (50%)
 Frame = +2

Query: 86   PVPADADSPKFKTTIGSVKYTPEQNAITWSIKSFPGGKEYLMRAHFGLPSV 238
            P P   ++P+F  T G+V YT ++N +   ++S P     L +   G  +V
Sbjct: 1973 PPPHSPETPQFPPTTGAVLYTVKRNQVGPEVRSCPKASPRLQKEREGQKAV 2023


>UniRef50_A6EML1 Cluster: Branched-chain-amino-acid transaminase;
           n=1; unidentified eubacterium SCB49|Rep:
           Branched-chain-amino-acid transaminase - unidentified
           eubacterium SCB49
          Length = 364

 Score = 31.9 bits (69), Expect = 7.7
 Identities = 12/39 (30%), Positives = 21/39 (53%)
 Frame = +2

Query: 65  NNVEIIIPVPADADSPKFKTTIGSVKYTPEQNAITWSIK 181
           NNV+  +  P D+ S KFK  +  ++Y   ++   W +K
Sbjct: 324 NNVDYALTKPEDSYSTKFKKELMDIQYNKSEDPFGWRVK 362


>UniRef50_Q5TX05 Cluster: ENSANGP00000029503; n=2; Culicidae|Rep:
           ENSANGP00000029503 - Anopheles gambiae str. PEST
          Length = 569

 Score = 31.9 bits (69), Expect = 7.7
 Identities = 12/20 (60%), Positives = 15/20 (75%)
 Frame = -2

Query: 234 DGKPKWALIKYSLPPGNDLI 175
           DGK KW L+   LPPGND++
Sbjct: 419 DGKKKWNLMLNVLPPGNDVV 438


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 456,118,965
Number of Sequences: 1657284
Number of extensions: 9104805
Number of successful extensions: 21878
Number of sequences better than 10.0: 69
Number of HSP's better than 10.0 without gapping: 21373
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 21820
length of database: 575,637,011
effective HSP length: 94
effective length of database: 419,852,315
effective search space used: 27290400475
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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