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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= P5PG0794
         (434 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Y10498-1|CAA71523.3|  266|Homo sapiens thymidine kinase 2 protein.     64   2e-10
BC142970-1|AAI42971.1|  216|Homo sapiens TK2 protein protein.          64   2e-10
BC134344-1|AAI34345.1|  229|Homo sapiens TK2 protein protein.          64   2e-10
AF521891-1|AAN73847.1|  307|Homo sapiens thymidine kinase protein.     64   2e-10
U80628-1|AAC51168.1|  224|Homo sapiens thymidine kinase 2 isofor...    62   6e-10
U77088-1|AAC51167.1|  234|Homo sapiens thymidine kinase 2 protein.     62   6e-10
U41668-1|AAC50624.1|  277|Homo sapiens deoxyguanosine kinase pro...    42   0.001
X97386-1|CAA66054.1|  260|Homo sapiens deoxyguanosine kinase pro...    41   0.002
BC015757-1|AAH15757.1|  277|Homo sapiens deoxyguanosine kinase p...    41   0.002
AC073046-3|AAX88910.1|  277|Homo sapiens unknown protein.              41   0.002
M60527-1|AAA35752.1|  260|Homo sapiens deoxycytidine kinase prot...    31   2.3  
CR541876-1|CAG46674.1|  260|Homo sapiens DCK protein.                  31   2.3  
CR536527-1|CAG38764.1|  260|Homo sapiens DCK protein.                  31   2.3  
BT019942-1|AAV38745.1|  260|Homo sapiens deoxycytidine kinase pr...    31   2.3  
BT019941-1|AAV38744.1|  260|Homo sapiens deoxycytidine kinase pr...    31   2.3  
BC114617-1|AAI14618.1|  260|Homo sapiens deoxycytidine kinase pr...    31   2.3  
BC103764-1|AAI03765.1|  260|Homo sapiens deoxycytidine kinase pr...    31   2.3  
BC101181-1|AAI01182.1|  424|Homo sapiens MMAA protein protein.         29   5.2  
BC101179-1|AAI01180.1|  418|Homo sapiens methylmalonic aciduria ...    29   5.2  
BC101178-1|AAI01179.1|  418|Homo sapiens methylmalonic aciduria ...    29   5.2  
AF524846-1|AAN77287.1|  418|Homo sapiens methylmalonic aciduria ...    29   5.2  
BC117686-1|AAI17687.1| 1683|Homo sapiens SHPRH protein protein.        29   6.9  
AY163808-1|AAO06907.1| 1659|Homo sapiens helicase-like protein p...    29   6.9  
AY161136-1|AAO26201.1| 1683|Homo sapiens SNF2 histone linker PHD...    29   6.9  
AL451145-1|CAH70765.1| 1683|Homo sapiens SNF2 histone linker PHD...    29   6.9  
AL356599-2|CAI41120.1| 1683|Homo sapiens SNF2 histone linker PHD...    29   6.9  
AK131259-1|BAD18437.1|  512|Homo sapiens   protein.                    29   6.9  
AB095943-1|BAC23119.1| 1092|Homo sapiens KIAA2023 protein protein.     29   6.9  

>Y10498-1|CAA71523.3|  266|Homo sapiens thymidine kinase 2 protein.
          Length = 266

 Score = 64.1 bits (149), Expect = 2e-10
 Identities = 30/65 (46%), Positives = 42/65 (64%), Gaps = 4/65 (6%)
 Frame = +3

Query: 153 VSIEGNIGSGKSTCIKFFNKFHNVEHHTEPLHEWRDVSGHNLLSLMYSGSEEMDL----Y 320
           + +EGNI SGK+TC++FF+   +VE  TEP+ +WR+V GHN L LMY  +    L    Y
Sbjct: 53  ICVEGNIASGKTTCLEFFSNATDVEVLTEPVSKWRNVRGHNPLGLMYHDASRWGLTLQTY 112

Query: 321 IPXTM 335
           +  TM
Sbjct: 113 VQLTM 117


>BC142970-1|AAI42971.1|  216|Homo sapiens TK2 protein protein.
          Length = 216

 Score = 64.1 bits (149), Expect = 2e-10
 Identities = 30/65 (46%), Positives = 42/65 (64%), Gaps = 4/65 (6%)
 Frame = +3

Query: 153 VSIEGNIGSGKSTCIKFFNKFHNVEHHTEPLHEWRDVSGHNLLSLMYSGSEEMDL----Y 320
           + +EGNI SGK+TC++FF+   +VE  TEP+ +WR+V GHN L LMY  +    L    Y
Sbjct: 4   ICVEGNIASGKTTCLEFFSNATDVEVLTEPVSKWRNVRGHNPLGLMYHDASRWGLTLQTY 63

Query: 321 IPXTM 335
           +  TM
Sbjct: 64  VQLTM 68


>BC134344-1|AAI34345.1|  229|Homo sapiens TK2 protein protein.
          Length = 229

 Score = 64.1 bits (149), Expect = 2e-10
 Identities = 30/65 (46%), Positives = 42/65 (64%), Gaps = 4/65 (6%)
 Frame = +3

Query: 153 VSIEGNIGSGKSTCIKFFNKFHNVEHHTEPLHEWRDVSGHNLLSLMYSGSEEMDL----Y 320
           + +EGNI SGK+TC++FF+   +VE  TEP+ +WR+V GHN L LMY  +    L    Y
Sbjct: 17  ICVEGNIASGKTTCLEFFSNATDVEVLTEPVSKWRNVRGHNPLGLMYHDASRWGLTLQTY 76

Query: 321 IPXTM 335
           +  TM
Sbjct: 77  VQLTM 81


>AF521891-1|AAN73847.1|  307|Homo sapiens thymidine kinase protein.
          Length = 307

 Score = 64.1 bits (149), Expect = 2e-10
 Identities = 30/65 (46%), Positives = 42/65 (64%), Gaps = 4/65 (6%)
 Frame = +3

Query: 153 VSIEGNIGSGKSTCIKFFNKFHNVEHHTEPLHEWRDVSGHNLLSLMYSGSEEMDL----Y 320
           + +EGNI SGK+TC++FF+   +VE  TEP+ +WR+V GHN L LMY  +    L    Y
Sbjct: 95  ICVEGNIASGKTTCLEFFSNATDVEVLTEPVSKWRNVRGHNPLGLMYHDASRWGLTLQTY 154

Query: 321 IPXTM 335
           +  TM
Sbjct: 155 VQLTM 159


>U80628-1|AAC51168.1|  224|Homo sapiens thymidine kinase 2 isoform B
           protein.
          Length = 224

 Score = 62.5 bits (145), Expect = 6e-10
 Identities = 29/65 (44%), Positives = 41/65 (63%), Gaps = 4/65 (6%)
 Frame = +3

Query: 153 VSIEGNIGSGKSTCIKFFNKFHNVEHHTEPLHEWRDVSGHNLLSLMYSGSEEMDL----Y 320
           + +EGNI  GK+TC++FF+   +VE  TEP+ +WR+V GHN L LMY  +    L    Y
Sbjct: 12  ICVEGNIAGGKTTCLEFFSNATDVEVLTEPVSKWRNVRGHNPLGLMYHDASRWGLTLQTY 71

Query: 321 IPXTM 335
           +  TM
Sbjct: 72  VQLTM 76


>U77088-1|AAC51167.1|  234|Homo sapiens thymidine kinase 2 protein.
          Length = 234

 Score = 62.5 bits (145), Expect = 6e-10
 Identities = 29/65 (44%), Positives = 41/65 (63%), Gaps = 4/65 (6%)
 Frame = +3

Query: 153 VSIEGNIGSGKSTCIKFFNKFHNVEHHTEPLHEWRDVSGHNLLSLMYSGSEEMDL----Y 320
           + +EGNI  GK+TC++FF+   +VE  TEP+ +WR+V GHN L LMY  +    L    Y
Sbjct: 22  ICVEGNIAGGKTTCLEFFSNATDVEVLTEPVSKWRNVRGHNPLGLMYHDASRWGLTLQTY 81

Query: 321 IPXTM 335
           +  TM
Sbjct: 82  VQLTM 86


>U41668-1|AAC50624.1|  277|Homo sapiens deoxyguanosine kinase
           protein.
          Length = 277

 Score = 41.5 bits (93), Expect = 0.001
 Identities = 32/86 (37%), Positives = 43/86 (50%), Gaps = 13/86 (15%)
 Frame = +3

Query: 144 PFRVSIEGNIGSGKSTCIKFFNKFHNVEH-HTEPLHEWRDV--SGH----------NLLS 284
           P R+SIEGNI  GKST +K   K +   H  TEP+  W+++  +G+          NLL 
Sbjct: 38  PRRLSIEGNIAVGKSTFVKLLTKTYPEWHVATEPVATWQNIQAAGNQKACTAQSLGNLLD 97

Query: 285 LMYSGSEEMDLYIPXTMYIXSRLKIQ 362
           +MY        Y   T    SRLK+Q
Sbjct: 98  MMYREPARWS-YTFQTFSFLSRLKVQ 122


>X97386-1|CAA66054.1|  260|Homo sapiens deoxyguanosine kinase
           protein.
          Length = 260

 Score = 41.1 bits (92), Expect = 0.002
 Identities = 32/86 (37%), Positives = 41/86 (47%), Gaps = 13/86 (15%)
 Frame = +3

Query: 144 PFRVSIEGNIGSGKSTCIKFFNKFHNVEH-HTEPLHEWRDV------------SGHNLLS 284
           P R+SIEGNI  GKST +K   K +   H  TEP+  W+++            S  NLL 
Sbjct: 21  PRRLSIEGNIAVGKSTFVKLLTKTYPEWHVATEPVATWQNIQAAGTQKACTAQSLGNLLD 80

Query: 285 LMYSGSEEMDLYIPXTMYIXSRLKIQ 362
           +MY        Y   T    SRLK+Q
Sbjct: 81  MMYREPARWS-YTFQTFSFLSRLKVQ 105


>BC015757-1|AAH15757.1|  277|Homo sapiens deoxyguanosine kinase
           protein.
          Length = 277

 Score = 41.1 bits (92), Expect = 0.002
 Identities = 32/86 (37%), Positives = 41/86 (47%), Gaps = 13/86 (15%)
 Frame = +3

Query: 144 PFRVSIEGNIGSGKSTCIKFFNKFHNVEH-HTEPLHEWRDV------------SGHNLLS 284
           P R+SIEGNI  GKST +K   K +   H  TEP+  W+++            S  NLL 
Sbjct: 38  PRRLSIEGNIAVGKSTFVKLLTKTYPEWHVATEPVATWQNIQAAGTQKACTAQSLGNLLD 97

Query: 285 LMYSGSEEMDLYIPXTMYIXSRLKIQ 362
           +MY        Y   T    SRLK+Q
Sbjct: 98  MMYREPARWS-YTFQTFSFLSRLKVQ 122


>AC073046-3|AAX88910.1|  277|Homo sapiens unknown protein.
          Length = 277

 Score = 41.1 bits (92), Expect = 0.002
 Identities = 32/86 (37%), Positives = 41/86 (47%), Gaps = 13/86 (15%)
 Frame = +3

Query: 144 PFRVSIEGNIGSGKSTCIKFFNKFHNVEH-HTEPLHEWRDV------------SGHNLLS 284
           P R+SIEGNI  GKST +K   K +   H  TEP+  W+++            S  NLL 
Sbjct: 38  PRRLSIEGNIAVGKSTFVKLLTKTYPEWHVATEPVATWQNIQAAGTQKACTAQSLGNLLD 97

Query: 285 LMYSGSEEMDLYIPXTMYIXSRLKIQ 362
           +MY        Y   T    SRLK+Q
Sbjct: 98  MMYREPARWS-YTFQTFSFLSRLKVQ 122


>M60527-1|AAA35752.1|  260|Homo sapiens deoxycytidine kinase
           protein.
          Length = 260

 Score = 30.7 bits (66), Expect = 2.3
 Identities = 15/39 (38%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
 Frame = +3

Query: 150 RVSIEGNIGSGKSTCIKFFNKF-HNVEHHTEPLHEWRDV 263
           ++SIEGNI +GKST +    +   + E   EP+  W +V
Sbjct: 23  KISIEGNIAAGKSTFVNILKQLCEDWEVVPEPVARWCNV 61


>CR541876-1|CAG46674.1|  260|Homo sapiens DCK protein.
          Length = 260

 Score = 30.7 bits (66), Expect = 2.3
 Identities = 15/39 (38%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
 Frame = +3

Query: 150 RVSIEGNIGSGKSTCIKFFNKF-HNVEHHTEPLHEWRDV 263
           ++SIEGNI +GKST +    +   + E   EP+  W +V
Sbjct: 23  KISIEGNIAAGKSTFVNILKQLCEDWEVVPEPVARWCNV 61


>CR536527-1|CAG38764.1|  260|Homo sapiens DCK protein.
          Length = 260

 Score = 30.7 bits (66), Expect = 2.3
 Identities = 15/39 (38%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
 Frame = +3

Query: 150 RVSIEGNIGSGKSTCIKFFNKF-HNVEHHTEPLHEWRDV 263
           ++SIEGNI +GKST +    +   + E   EP+  W +V
Sbjct: 23  KISIEGNIAAGKSTFVNILKQLCEDWEVVPEPVARWCNV 61


>BT019942-1|AAV38745.1|  260|Homo sapiens deoxycytidine kinase
           protein.
          Length = 260

 Score = 30.7 bits (66), Expect = 2.3
 Identities = 15/39 (38%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
 Frame = +3

Query: 150 RVSIEGNIGSGKSTCIKFFNKF-HNVEHHTEPLHEWRDV 263
           ++SIEGNI +GKST +    +   + E   EP+  W +V
Sbjct: 23  KISIEGNIAAGKSTFVNILKQLCEDWEVVPEPVARWCNV 61


>BT019941-1|AAV38744.1|  260|Homo sapiens deoxycytidine kinase
           protein.
          Length = 260

 Score = 30.7 bits (66), Expect = 2.3
 Identities = 15/39 (38%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
 Frame = +3

Query: 150 RVSIEGNIGSGKSTCIKFFNKF-HNVEHHTEPLHEWRDV 263
           ++SIEGNI +GKST +    +   + E   EP+  W +V
Sbjct: 23  KISIEGNIAAGKSTFVNILKQLCEDWEVVPEPVARWCNV 61


>BC114617-1|AAI14618.1|  260|Homo sapiens deoxycytidine kinase
           protein.
          Length = 260

 Score = 30.7 bits (66), Expect = 2.3
 Identities = 15/39 (38%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
 Frame = +3

Query: 150 RVSIEGNIGSGKSTCIKFFNKF-HNVEHHTEPLHEWRDV 263
           ++SIEGNI +GKST +    +   + E   EP+  W +V
Sbjct: 23  KISIEGNIAAGKSTFVNILKQLCEDWEVVPEPVARWCNV 61


>BC103764-1|AAI03765.1|  260|Homo sapiens deoxycytidine kinase
           protein.
          Length = 260

 Score = 30.7 bits (66), Expect = 2.3
 Identities = 15/39 (38%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
 Frame = +3

Query: 150 RVSIEGNIGSGKSTCIKFFNKF-HNVEHHTEPLHEWRDV 263
           ++SIEGNI +GKST +    +   + E   EP+  W +V
Sbjct: 23  KISIEGNIAAGKSTFVNILKQLCEDWEVVPEPVARWCNV 61


>BC101181-1|AAI01182.1|  424|Homo sapiens MMAA protein protein.
          Length = 424

 Score = 29.5 bits (63), Expect = 5.2
 Identities = 13/29 (44%), Positives = 17/29 (58%)
 Frame = +3

Query: 147 FRVSIEGNIGSGKSTCIKFFNKFHNVEHH 233
           FRV + G  G+GKST I++F K      H
Sbjct: 144 FRVGLSGPPGAGKSTFIEYFGKMLTERGH 172


>BC101179-1|AAI01180.1|  418|Homo sapiens methylmalonic aciduria
           (cobalamin deficiency) cblA type protein.
          Length = 418

 Score = 29.5 bits (63), Expect = 5.2
 Identities = 13/29 (44%), Positives = 17/29 (58%)
 Frame = +3

Query: 147 FRVSIEGNIGSGKSTCIKFFNKFHNVEHH 233
           FRV + G  G+GKST I++F K      H
Sbjct: 144 FRVGLSGPPGAGKSTFIEYFGKMLTERGH 172


>BC101178-1|AAI01179.1|  418|Homo sapiens methylmalonic aciduria
           (cobalamin deficiency) cblA type protein.
          Length = 418

 Score = 29.5 bits (63), Expect = 5.2
 Identities = 13/29 (44%), Positives = 17/29 (58%)
 Frame = +3

Query: 147 FRVSIEGNIGSGKSTCIKFFNKFHNVEHH 233
           FRV + G  G+GKST I++F K      H
Sbjct: 144 FRVGLSGPPGAGKSTFIEYFGKMLTERGH 172


>AF524846-1|AAN77287.1|  418|Homo sapiens methylmalonic aciduria
           type A protein.
          Length = 418

 Score = 29.5 bits (63), Expect = 5.2
 Identities = 13/29 (44%), Positives = 17/29 (58%)
 Frame = +3

Query: 147 FRVSIEGNIGSGKSTCIKFFNKFHNVEHH 233
           FRV + G  G+GKST I++F K      H
Sbjct: 144 FRVGLSGPPGAGKSTFIEYFGKMLTERGH 172


>BC117686-1|AAI17687.1| 1683|Homo sapiens SHPRH protein protein.
          Length = 1683

 Score = 29.1 bits (62), Expect = 6.9
 Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 1/40 (2%)
 Frame = +3

Query: 168 NIGSGKSTCIKFFNKFHNVEHHTEPL-HEWRDVSGHNLLS 284
           ++   KSTCI  FN+ H  E   E L H   DV   N +S
Sbjct: 611 DVAMSKSTCISEFNQEHETEDCAESLNHADSDVPPSNTMS 650


>AY163808-1|AAO06907.1| 1659|Homo sapiens helicase-like protein
           protein.
          Length = 1659

 Score = 29.1 bits (62), Expect = 6.9
 Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 1/40 (2%)
 Frame = +3

Query: 168 NIGSGKSTCIKFFNKFHNVEHHTEPL-HEWRDVSGHNLLS 284
           ++   KSTCI  FN+ H  E   E L H   DV   N +S
Sbjct: 611 DVAMSKSTCISEFNQEHETEDCAESLNHADSDVPPSNTMS 650


>AY161136-1|AAO26201.1| 1683|Homo sapiens SNF2 histone linker PHD
           RING helicase protein.
          Length = 1683

 Score = 29.1 bits (62), Expect = 6.9
 Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 1/40 (2%)
 Frame = +3

Query: 168 NIGSGKSTCIKFFNKFHNVEHHTEPL-HEWRDVSGHNLLS 284
           ++   KSTCI  FN+ H  E   E L H   DV   N +S
Sbjct: 611 DVAMSKSTCISEFNQEHETEDCAESLNHADSDVPPSNTMS 650


>AL451145-1|CAH70765.1| 1683|Homo sapiens SNF2 histone linker PHD
           RING helicase protein.
          Length = 1683

 Score = 29.1 bits (62), Expect = 6.9
 Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 1/40 (2%)
 Frame = +3

Query: 168 NIGSGKSTCIKFFNKFHNVEHHTEPL-HEWRDVSGHNLLS 284
           ++   KSTCI  FN+ H  E   E L H   DV   N +S
Sbjct: 611 DVAMSKSTCISEFNQEHETEDCAESLNHADSDVPPSNTMS 650


>AL356599-2|CAI41120.1| 1683|Homo sapiens SNF2 histone linker PHD
           RING helicase protein.
          Length = 1683

 Score = 29.1 bits (62), Expect = 6.9
 Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 1/40 (2%)
 Frame = +3

Query: 168 NIGSGKSTCIKFFNKFHNVEHHTEPL-HEWRDVSGHNLLS 284
           ++   KSTCI  FN+ H  E   E L H   DV   N +S
Sbjct: 611 DVAMSKSTCISEFNQEHETEDCAESLNHADSDVPPSNTMS 650


>AK131259-1|BAD18437.1|  512|Homo sapiens   protein.
          Length = 512

 Score = 29.1 bits (62), Expect = 6.9
 Identities = 21/62 (33%), Positives = 33/62 (53%), Gaps = 7/62 (11%)
 Frame = +3

Query: 132 VRKRPFRVSIEGNIGSGKSTCI-KFFNKFHN----VEHHTEPLHEWRDVS-GH-NLLSLM 290
           V+K+     +EGNI  GK+T + +  N+       VE   EP+ +W+DV   H N+L   
Sbjct: 192 VQKKRLTFCVEGNISVGKTTFLQRIANETIELRDLVEVVPEPISKWQDVGPDHFNILDAF 251

Query: 291 YS 296
           Y+
Sbjct: 252 YA 253


>AB095943-1|BAC23119.1| 1092|Homo sapiens KIAA2023 protein protein.
          Length = 1092

 Score = 29.1 bits (62), Expect = 6.9
 Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 1/40 (2%)
 Frame = +3

Query: 168 NIGSGKSTCIKFFNKFHNVEHHTEPL-HEWRDVSGHNLLS 284
           ++   KSTCI  FN+ H  E   E L H   DV   N +S
Sbjct: 196 DVAMSKSTCISEFNQEHETEDCAESLNHADSDVPPSNTMS 235


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 55,158,837
Number of Sequences: 237096
Number of extensions: 1009872
Number of successful extensions: 1880
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 1803
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1880
length of database: 76,859,062
effective HSP length: 83
effective length of database: 57,180,094
effective search space used: 3487985734
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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