Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= P5PG0669
(553 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AB209735-1|BAD92972.1| 1976|Homo sapiens fibrillin 2 (congenital... 200 2e-51
U03272-1|AAA18950.1| 2911|Homo sapiens fibrillin-2 protein. 199 5e-51
X63556-1|CAA45118.1| 3002|Homo sapiens fibrillin protein. 192 9e-49
L13923-1|AAB02036.1| 2871|Homo sapiens fibrillin protein. 192 9e-49
AB177803-1|BAD16739.1| 2871|Homo sapiens fibrillin 1 protein. 192 9e-49
AY165865-1|AAO18147.1| 2809|Homo sapiens fibrillin-3 short form ... 184 2e-46
AY165864-1|AAO18146.1| 2809|Homo sapiens fibrillin-3 short form ... 184 2e-46
AY165863-1|AAO18145.1| 2809|Homo sapiens fibrillin-3 short form ... 184 2e-46
AB177800-1|BAD16736.1| 2809|Homo sapiens fibrillin 3 protein. 184 2e-46
AB177799-1|BAD16735.1| 2809|Homo sapiens fibrillin 3 protein. 184 2e-46
AB177798-1|BAD16734.1| 2809|Homo sapiens fibrillin 3 protein. 184 2e-46
AB177797-1|BAD16733.1| 2809|Homo sapiens fibrillin 3 protein. 184 2e-46
AB053450-1|BAB47408.2| 2816|Homo sapiens fibrillin3 protein. 184 2e-46
AK131282-1|BAD18457.1| 872|Homo sapiens protein ( Homo sapiens ... 177 2e-44
AF051345-1|AAC39880.2| 1624|Homo sapiens latent transforming gro... 168 1e-41
AF051344-1|AAC39879.2| 1557|Homo sapiens latent transforming gro... 168 1e-41
Y13622-1|CAA73944.1| 1587|Homo sapiens latent TGF-beta binding p... 167 3e-41
M34057-1|AAA61160.1| 1394|Homo sapiens TGFB1 protein. 162 6e-40
BC130289-1|AAI30290.1| 1395|Homo sapiens latent transforming gro... 162 6e-40
AF489528-1|AAM03124.1| 1394|Homo sapiens transforming growth fac... 162 6e-40
AC019127-1|AAY24260.1| 697|Homo sapiens unknown protein. 162 6e-40
AB208801-1|BAD92038.1| 1348|Homo sapiens latent transforming gro... 162 6e-40
X62008-1|CAB56534.1| 517|Homo sapiens fibrillin 15 protein. 157 3e-38
AK027344-1|BAB55049.1| 741|Homo sapiens protein ( Homo sapiens ... 157 3e-38
AB177802-1|BAD16738.1| 1365|Homo sapiens fibrillin 1 protein. 157 3e-38
AB208840-1|BAD92077.1| 830|Homo sapiens fibrillin 1 variant pro... 152 9e-37
BC008761-1|AAH08761.2| 743|Homo sapiens LTBP3 protein protein. 151 2e-36
AK024477-1|BAB15767.1| 1382|Homo sapiens FLJ00070 protein protein. 151 2e-36
AF135960-1|AAF62352.3| 1256|Homo sapiens latent transforming gro... 151 2e-36
X62009-1|CAB56757.1| 754|Homo sapiens fibrillin 5 protein. 149 8e-36
BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA seq... 146 3e-35
AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA seq... 146 3e-35
AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA seq... 146 3e-35
AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA seq... 146 3e-35
AL133553-4|CAI17860.1| 240|Homo sapiens protein ( e PRG4 gene f... 146 3e-35
AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA seq... 146 3e-35
AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA seq... 146 3e-35
AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA seq... 146 3e-35
AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA seq... 146 3e-35
AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein. 146 3e-35
AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein. 146 5e-35
Z37976-1|CAA86030.1| 1821|Homo sapiens LTBP-2 precursor protein. 145 8e-35
S82451-1|AAB37459.1| 1821|Homo sapiens latent transforming growt... 145 8e-35
BC078659-1|AAH78659.1| 1821|Homo sapiens latent transforming gro... 145 8e-35
AB209865-1|BAD93102.1| 1700|Homo sapiens latent transforming gro... 145 8e-35
X82494-1|CAA57876.1| 1184|Homo sapiens fibulin-2 protein. 144 2e-34
BC051690-1|AAH51690.1| 1184|Homo sapiens fibulin 2 protein. 144 2e-34
AY130459-1|AAN05436.1| 1231|Homo sapiens fibulin 2 protein. 144 2e-34
AY130458-1|AAN05435.1| 1231|Homo sapiens fibulin 2 protein. 144 2e-34
AB209212-1|BAD92449.1| 418|Homo sapiens EGF-containing fibulin-... 143 3e-34
U03877-1|AAA65590.1| 387|Homo sapiens extracellular protein pro... 143 4e-34
BC098561-1|AAH98561.1| 493|Homo sapiens EGF-containing fibulin-... 143 4e-34
BC014410-1|AAH14410.1| 493|Homo sapiens EGF-containing fibulin-... 143 4e-34
AY004330-1|AAK11491.1| 493|Homo sapiens EGF-containing fibulin-... 143 4e-34
AC010895-1|AAY14669.1| 320|Homo sapiens unknown protein. 143 4e-34
AF054502-1|AAC39882.1| 669|Homo sapiens latent transforming gro... 140 4e-33
AL513320-1|CAI14334.1| 1229|Homo sapiens multiple EGF-like-domai... 138 2e-32
AL512413-3|CAH70834.1| 1229|Homo sapiens multiple EGF-like-domai... 138 2e-32
AB231860-1|BAE19678.1| 1640|Homo sapiens hypothetical protein pr... 138 2e-32
AB011539-1|BAA32467.2| 1246|Homo sapiens MEGF6 protein. 138 2e-32
CR457140-1|CAG33421.1| 448|Homo sapiens FBLN5 protein. 136 4e-32
BC022280-1|AAH22280.1| 448|Homo sapiens fibulin 5 protein. 136 4e-32
AJ133490-1|CAB38568.1| 448|Homo sapiens fibulin-5 protein. 136 4e-32
AF112152-1|AAD41768.1| 448|Homo sapiens developmental arteries ... 136 4e-32
BC022497-1|AAH22497.1| 683|Homo sapiens fibulin 1 protein. 135 8e-32
Z99756-1|CAI18854.1| 988|Homo sapiens protein ( Human DNA seque... 135 1e-31
Z82214-3|CAI21674.1| 988|Homo sapiens protein ( Human DNA seque... 135 1e-31
Z98047-1|CAI19628.1| 703|Homo sapiens fibulin 1 protein. 134 1e-31
Z95331-3|CAI41717.1| 703|Homo sapiens fibulin 1 protein. 134 1e-31
AL021391-3|CAI18930.1| 703|Homo sapiens fibulin 1 protein. 134 1e-31
AK075566-1|BAC11705.1| 638|Homo sapiens protein ( Homo sapiens ... 134 1e-31
AF525689-1|AAN77133.1| 988|Homo sapiens signal peptide-CUB-EGF-... 134 1e-31
AF217999-1|AAG17241.1| 495|Homo sapiens unknown protein. 134 1e-31
AY358898-1|AAQ89257.1| 448|Homo sapiens FBLN5 protein. 134 2e-31
AF093118-1|AAC62107.1| 448|Homo sapiens UP50 protein. 133 4e-31
X53743-1|CAA37772.1| 683|Homo sapiens fibulin-1 C protein. 132 8e-31
X53742-1|CAA37771.1| 601|Homo sapiens fibulin-1 B protein. 132 8e-31
X53741-1|CAA37770.1| 566|Homo sapiens fibulin-1 A protein. 132 8e-31
U01244-1|AAB17099.1| 703|Homo sapiens fibulin-1D protein. 132 8e-31
AF126110-1|AAK37822.1| 703|Homo sapiens fibulin-1 isoform D pre... 132 8e-31
Z97832-1|CAI20187.1| 993|Homo sapiens protein ( Human DNA seque... 131 1e-30
AY639608-1|AAU08347.1| 993|Homo sapiens signal peptide, CUB and... 131 1e-30
AF452494-1|AAN76808.1| 993|Homo sapiens CUB and EGF containing ... 131 1e-30
AK092062-1|BAC03798.1| 880|Homo sapiens protein ( Homo sapiens ... 131 2e-30
BC052263-1|AAH52263.2| 992|Homo sapiens signal peptide, CUB dom... 130 2e-30
AY358895-1|AAQ89254.1| 915|Homo sapiens MATN2 protein. 130 2e-30
CR541934-1|CAG46732.1| 443|Homo sapiens EFEMP2 protein. 130 4e-30
BC010456-1|AAH10456.1| 443|Homo sapiens EGF-containing fibulin-... 130 4e-30
AY358899-1|AAQ89258.1| 443|Homo sapiens EFEMP2 protein. 130 4e-30
AJ132819-1|CAA10791.2| 443|Homo sapiens fibulin-4 protein. 130 4e-30
AF109121-1|AAF65188.1| 443|Homo sapiens EGF-containing fibulin-... 130 4e-30
AB030655-1|BAA92880.1| 443|Homo sapiens mutant p53 binding prot... 130 4e-30
AF124486-1|AAG45245.1| 443|Homo sapiens fibulin-like extracellu... 128 2e-29
AF093119-1|AAC62108.1| 439|Homo sapiens UPH1 protein. 127 3e-29
L13720-1|AAA58494.1| 678|Homo sapiens growth-arrest-specific pr... 124 2e-28
EF631974-1|ABR09277.1| 678|Homo sapiens growth arrest-specific ... 124 2e-28
BX072579-3|CAH71174.1| 678|Homo sapiens growth arrest-specific ... 124 2e-28
BC038984-1|AAH38984.1| 678|Homo sapiens growth arrest-specific ... 124 2e-28
AY256843-1|AAO84057.1| 678|Homo sapiens growth arrested-specifi... 124 2e-28
AK126533-1|BAC86580.1| 624|Homo sapiens protein ( Homo sapiens ... 124 2e-28
BC111690-1|AAI11691.1| 807|Homo sapiens SCUBE2 protein protein. 123 5e-28
AK131552-1|BAD18686.1| 682|Homo sapiens protein ( Homo sapiens ... 123 5e-28
AK123039-1|BAC85521.1| 971|Homo sapiens protein ( Homo sapiens ... 123 5e-28
AJ400877-1|CAB92285.1| 999|Homo sapiens CEGP1 protein protein. 123 5e-28
AJ295142-1|CAC82720.1| 652|Homo sapiens C1q receptor protein pr... 122 6e-28
U94333-1|AAB53110.1| 652|Homo sapiens C1qR(p) protein. 122 8e-28
BC028075-1|AAH28075.1| 652|Homo sapiens CD93 molecule protein. 122 8e-28
AL118508-1|CAC00597.1| 652|Homo sapiens complement component 1,... 122 8e-28
AF054501-1|AAC39881.1| 161|Homo sapiens latent transforming gro... 122 8e-28
AB209895-1|BAD93132.1| 671|Homo sapiens complement component 1,... 122 8e-28
U69263-1|AAC51260.2| 956|Homo sapiens matrilin-2 precursor prot... 122 1e-27
BC016394-1|AAH16394.1| 715|Homo sapiens MATN2 protein protein. 122 1e-27
BC010444-1|AAH10444.1| 937|Homo sapiens matrilin 2 protein. 122 1e-27
AL833931-1|CAD38787.1| 1016|Homo sapiens hypothetical protein pr... 122 1e-27
AK075489-1|BAC11648.1| 451|Homo sapiens rase 7. protein. 118 1e-26
X12892-1|CAA31383.1| 650|Homo sapiens protein ( H.sapiens mRNA ... 112 9e-25
M14338-1|AAA60181.1| 650|Homo sapiens protein S precursor protein. 112 9e-25
AY358336-1|AAQ88702.1| 509|Homo sapiens DFLL295 protein. 111 1e-24
Y00692-1|CAA68687.1| 676|Homo sapiens preproprotein S protein. 111 2e-24
M57853-1|AAA60357.1| 676|Homo sapiens S protein protein. 111 2e-24
M36564-1|AAA60180.1| 650|Homo sapiens PROS1 protein. 111 2e-24
M15036-1|AAA36479.1| 676|Homo sapiens protein ( Human vitamin K... 111 2e-24
BC015801-1|AAH15801.1| 676|Homo sapiens PROS1 protein protein. 111 2e-24
AY308744-1|AAP45054.1| 497|Homo sapiens protein S (alpha) protein. 111 2e-24
X81479-1|CAA57232.1| 886|Homo sapiens EMR1 protein. 111 2e-24
DQ217942-1|ABB70739.1| 886|Homo sapiens EGF-like module contain... 109 6e-24
BC059395-1|AAH59395.1| 821|Homo sapiens EMR1 protein protein. 109 6e-24
BC038587-1|AAH38587.1| 553|Homo sapiens EGF-like-domain, multip... 109 6e-24
AY358333-1|AAQ88699.1| 338|Homo sapiens EGFL6 protein. 109 6e-24
AK075214-1|BAC11477.1| 553|Homo sapiens protein ( Homo sapiens ... 109 6e-24
AJ245671-1|CAB92132.1| 554|Homo sapiens hypothetical protein pr... 109 6e-24
AF186084-1|AAF27812.1| 553|Homo sapiens epidermal growth factor... 109 6e-24
AB065918-1|BAC06133.1| 929|Homo sapiens seven transmembrane hel... 109 6e-24
AK027775-1|BAB55358.1| 537|Homo sapiens protein ( Homo sapiens ... 108 1e-23
BC127263-1|AAI27264.1| 363|Homo sapiens SCUBE1 protein protein. 107 2e-23
BC047916-1|AAH47916.1| 347|Homo sapiens SCUBE1 protein protein. 107 2e-23
AL021578-3|CAB46380.1| 622|Homo sapiens matrilin 4 protein. 103 6e-22
AL021578-1|CAI21077.1| 432|Homo sapiens matrilin 4 protein. 103 6e-22
AF193055-1|AAG22483.1| 474|Homo sapiens unknown protein. 102 7e-22
AK131562-1|BAD18695.1| 867|Homo sapiens protein ( Homo sapiens ... 102 1e-21
AK056571-1|BAB71219.1| 955|Homo sapiens protein ( Homo sapiens ... 102 1e-21
D89629-1|BAB46925.1| 815|Homo sapiens cerebral protein-12 protein. 101 2e-21
D83018-1|BAA11681.1| 816|Homo sapiens nel-related protein 2 pro... 101 2e-21
BC020544-1|AAH20544.1| 816|Homo sapiens NELL2 protein protein. 101 2e-21
BC142624-1|AAI42625.1| 955|Homo sapiens von Willebrand factor C... 101 2e-21
AB209448-1|BAD92685.1| 1241|Homo sapiens nidogen (enactin) varia... 101 2e-21
AK074499-1|BAC11024.1| 636|Homo sapiens protein ( Homo sapiens ... 100 3e-21
BC071562-1|AAH71562.2| 1235|Homo sapiens NOTCH2 protein protein. 100 4e-21
AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 100 4e-21
AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 100 4e-21
AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 100 4e-21
AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein. 100 4e-21
AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein. 100 4e-21
AL117551-1|CAB55988.1| 511|Homo sapiens hypothetical protein pr... 99 9e-21
AK222891-1|BAD96611.1| 810|Homo sapiens egf-like module contain... 99 9e-21
AF114491-1|AAF21974.1| 823|Homo sapiens EGF-like module EMR2 pr... 99 9e-21
AB065931-1|BAC06146.1| 837|Homo sapiens seven transmembrane hel... 99 9e-21
X05495-1|CAA29045.1| 575|Homo sapiens thrombomodulin protein. 99 1e-20
M16552-1|AAB59508.1| 575|Homo sapiens THBD protein. 99 1e-20
J02973-1|AAA61175.1| 575|Homo sapiens THBD protein. 99 1e-20
D00210-1|BAA00149.1| 575|Homo sapiens thrombomodulin precursor ... 99 1e-20
BC053357-1|AAH53357.1| 575|Homo sapiens thrombomodulin protein. 99 1e-20
BC035602-1|AAH35602.2| 575|Homo sapiens thrombomodulin protein. 99 1e-20
AL049651-2|CAB51954.1| 575|Homo sapiens thrombomodulin protein. 99 1e-20
AF495471-1|AAM03232.1| 575|Homo sapiens thrombomodulin protein. 99 1e-20
X82245-1|CAA57709.1| 1246|Homo sapiens nidogen protein. 98 2e-20
M30269-1|AAA59932.1| 1247|Homo sapiens nidogen protein. 98 2e-20
M27445-1|AAA57261.1| 581|Homo sapiens nidogen protein. 98 2e-20
AL139161-2|CAI23422.1| 1247|Homo sapiens nidogen 1 protein. 98 2e-20
AL122018-2|CAI22681.1| 1247|Homo sapiens nidogen 1 protein. 98 2e-20
AC005327-1|AAC27673.1| 287|Homo sapiens CD97_HUMAN, partial CDS... 98 2e-20
X94630-1|CAA64333.1| 835|Homo sapiens seven-span transmembrane ... 98 2e-20
U76764-1|AAB36682.1| 835|Homo sapiens CD97 protein. 98 2e-20
BC127005-1|AAI27006.1| 823|Homo sapiens egf-like module contain... 98 2e-20
BC127004-1|AAI27005.1| 823|Homo sapiens egf-like module contain... 98 2e-20
AB065966-1|BAC06178.1| 837|Homo sapiens seven transmembrane hel... 98 2e-20
Y13341-1|CAA73785.1| 310|Homo sapiens matrilin-3 precursor prot... 97 4e-20
D86425-1|BAA13087.1| 1376|Homo sapiens osteonidogen protein. 97 4e-20
BC139907-1|AAI39908.1| 486|Homo sapiens matrilin 3 protein. 97 4e-20
AJ224741-1|CAA12110.1| 486|Homo sapiens matrilin-3 protein. 97 4e-20
AJ223500-1|CAA11418.1| 1375|Homo sapiens nidogen-2 protein. 97 4e-20
AJ001047-1|CAA04501.1| 303|Homo sapiens Matrilin-3 protein. 97 4e-20
AC079145-2|AAX88937.1| 486|Homo sapiens unknown protein. 97 4e-20
AB009799-1|BAA24112.1| 1376|Homo sapiens osteonidogen protein. 97 4e-20
BC035608-1|AAH35608.1| 969|Homo sapiens NID2 protein protein. 95 2e-19
D83017-1|BAA11680.1| 810|Homo sapiens nel-related protein protein. 94 3e-19
BC096102-1|AAH96102.1| 810|Homo sapiens NEL-like 1 (chicken) pr... 94 3e-19
BC096101-1|AAH96101.1| 810|Homo sapiens NEL-like 1 (chicken) pr... 94 3e-19
BC069674-1|AAH69674.1| 810|Homo sapiens nel-like 1, precursor p... 94 3e-19
U57523-1|AAB06946.1| 446|Homo sapiens protein ( Human nel homol... 93 6e-19
BC096103-1|AAH96103.1| 763|Homo sapiens NELL1 protein protein. 93 8e-19
BC096100-1|AAH96100.1| 763|Homo sapiens NELL1 protein protein. 93 8e-19
AF029779-1|AAB84216.1| 1200|Homo sapiens hJAG2.del-E6 protein. 93 8e-19
Y14330-1|CAA74706.1| 1223|Homo sapiens jagged2 protein protein. 92 1e-18
U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein. 92 1e-18
U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein. 92 1e-18
D86566-1|BAA13116.1| 955|Homo sapiens notch related protein pro... 92 1e-18
BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 92 1e-18
BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 92 1e-18
BC063815-1|AAH63815.1| 647|Homo sapiens NOTCH4 protein protein. 92 1e-18
AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 92 1e-18
AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4 (Droso... 92 1e-18
AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4 (Droso... 92 1e-18
AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4 (Drosop... 92 1e-18
M17778-1|AAA36799.1| 640|Homo sapiens protein ( Human uromoduli... 91 3e-18
M15881-1|AAA36798.1| 640|Homo sapiens protein ( Human uromoduli... 91 3e-18
BC035975-1|AAH35975.1| 611|Homo sapiens UMOD protein protein. 91 3e-18
AY162970-1|AAO64446.1| 640|Homo sapiens uromodulin precursor pr... 91 3e-18
AF111170-2|AAD15562.1| 1238|Homo sapiens Jagged2 protein. 89 7e-18
BC151219-1|AAI51220.1| 581|Homo sapiens matrilin 4 protein. 89 1e-17
BC131763-1|AAI31764.1| 581|Homo sapiens matrilin 4 protein. 89 1e-17
AL021578-2|CAB39280.1| 581|Homo sapiens matrilin 4 protein. 89 1e-17
AJ007581-1|CAA07569.1| 581|Homo sapiens matrilin-4 protein. 89 1e-17
AC013451-1|AAF87081.1| 969|Homo sapiens LTBP-2 protein. 89 1e-17
AF020201-1|AAB71189.1| 1238|Homo sapiens Jagged 2 protein. 88 2e-17
BC053933-1|AAH53933.1| 239|Homo sapiens EMR2 protein protein. 88 2e-17
BC034949-1|AAH34949.1| 239|Homo sapiens EMR2 protein protein. 88 2e-17
AF029778-1|AAB84215.1| 1238|Homo sapiens Jagged2 protein. 88 2e-17
AF003521-1|AAB61285.1| 1238|Homo sapiens Jagged 2 protein. 88 2e-17
AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1, transl... 87 3e-17
AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1, transl... 87 3e-17
AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein va... 87 3e-17
M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein. 86 9e-17
AK123000-1|BAC85516.1| 1176|Homo sapiens 3 (HIVEP3). protein. 86 9e-17
AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein. 86 9e-17
U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein. 85 1e-16
AY720432-1|AAU14134.1| 1285|Homo sapiens crumbs-like protein 2 p... 85 1e-16
AL445489-4|CAI39793.1| 1285|Homo sapiens crumbs homolog 2 (Droso... 85 1e-16
AL445489-3|CAM14433.1| 1176|Homo sapiens crumbs homolog 2 (Droso... 85 1e-16
AL365504-3|CAI41011.1| 1285|Homo sapiens crumbs homolog 2 (Droso... 85 1e-16
AL365504-2|CAM21391.1| 1176|Homo sapiens crumbs homolog 2 (Droso... 85 1e-16
AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein. 85 1e-16
AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein. 85 1e-16
AB209447-1|BAD92684.1| 1289|Homo sapiens Notch homolog 3 variant... 85 1e-16
AB231861-1|BAE19679.1| 1950|Homo sapiens low-density lipoprotein... 85 2e-16
AB084910-1|BAD83615.1| 1905|Homo sapiens low density lipoprotein... 85 2e-16
AB011540-1|BAA32468.1| 1576|Homo sapiens MEGF7 protein. 85 2e-16
BC035784-1|AAH35784.1| 439|Homo sapiens hypothetical protein FL... 84 4e-16
AK094759-1|BAC04416.1| 439|Homo sapiens protein ( Homo sapiens ... 84 4e-16
AC092645-2|AAY14854.1| 439|Homo sapiens unknown protein. 84 4e-16
AB023961-1|BAB20317.1| 502|Homo sapiens notch4 protein. 84 4e-16
AK074396-1|BAB85069.1| 220|Homo sapiens protein ( Homo sapiens ... 83 5e-16
U77720-1|AAC51323.1| 1214|Homo sapiens transmembrane protein Jag... 83 8e-16
U73936-1|AAC52020.1| 1218|Homo sapiens Jagged 1 protein. 83 8e-16
U61276-1|AAB39007.1| 1218|Homo sapiens transmembrane protein Jag... 83 8e-16
BC126207-1|AAI26208.1| 1218|Homo sapiens jagged 1 (Alagille synd... 83 8e-16
BC126205-1|AAI26206.1| 1218|Homo sapiens jagged 1 (Alagille synd... 83 8e-16
BC098393-1|AAH98393.1| 1218|Homo sapiens jagged 1 (Alagille synd... 83 8e-16
AL731551-1|CAI40246.1| 3623|Homo sapiens cubilin (intrinsic fact... 83 8e-16
AL596445-1|CAH72450.1| 3623|Homo sapiens cubilin (intrinsic fact... 83 8e-16
AL365215-1|CAH73630.1| 3623|Homo sapiens cubilin (intrinsic fact... 83 8e-16
AL035456-3|CAC07198.1| 1218|Homo sapiens jagged 1 (Alagille synd... 83 8e-16
AF028593-1|AAB84053.1| 1218|Homo sapiens transmembrane protein J... 83 8e-16
AF243129-1|AAK61830.1| 3494|Homo sapiens intrinsic factor-vitami... 82 1e-15
AF034611-1|AAC82612.1| 3623|Homo sapiens intrinsic factor-B12 re... 82 1e-15
AY243503-1|AAQ89957.1| 3574|Homo sapiens selectin-like protein p... 79 8e-15
AL592463-2|CAH73558.1| 3548|Homo sapiens sushi, von Willebrand f... 79 8e-15
AL354982-2|CAH74139.1| 3548|Homo sapiens sushi, von Willebrand f... 79 8e-15
AL158158-3|CAI14068.1| 3548|Homo sapiens sushi, von Willebrand f... 79 8e-15
AK027870-1|BAB55420.1| 1316|Homo sapiens protein ( Homo sapiens ... 79 8e-15
AJ619977-1|CAF04067.1| 3574|Homo sapiens SEL-OB protein protein. 79 8e-15
X04571-1|CAA28240.1| 1207|Homo sapiens protein ( Human mRNA for ... 79 1e-14
BC113461-1|AAI13462.1| 1207|Homo sapiens epidermal growth factor... 79 1e-14
BC093731-1|AAH93731.1| 1207|Homo sapiens epidermal growth factor... 79 1e-14
AY506357-1|AAR84237.1| 1152|Homo sapiens truncated epidermal gro... 79 1e-14
AY043325-1|AAL10682.1| 1406|Homo sapiens CRB1 isoform II precurs... 79 1e-14
AY043324-1|AAL10681.1| 1376|Homo sapiens CRB1 isoform I precurso... 79 1e-14
AL513325-2|CAH72584.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 79 1e-14
AL139136-2|CAI15311.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 79 1e-14
AL136322-3|CAI16646.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 79 1e-14
AF154671-1|AAF01361.1| 1376|Homo sapiens CRB1 protein. 79 1e-14
AB208923-1|BAD92160.1| 441|Homo sapiens crumbs homolog 1 isofor... 79 1e-14
U77493-1|AAB19224.1| 263|Homo sapiens Notch2 protein. 78 2e-14
BC126440-1|AAI26441.1| 321|Homo sapiens OIT3 protein protein. 78 2e-14
AY358339-1|AAQ88705.1| 545|Homo sapiens PPFL826 protein. 78 2e-14
AY013707-1|AAG40096.2| 545|Homo sapiens LZP protein. 78 2e-14
AK096435-1|BAC04788.1| 545|Homo sapiens protein ( Homo sapiens ... 78 2e-14
BC105633-1|AAI05634.1| 757|Homo sapiens tumor endothelial marke... 78 2e-14
BC104484-1|AAI04485.1| 757|Homo sapiens tumor endothelial marke... 78 2e-14
BC051340-1|AAH51340.1| 757|Homo sapiens CD248 molecule, endosia... 78 2e-14
AJ295846-1|CAC34381.1| 757|Homo sapiens endosialin protein prot... 78 2e-14
AF279142-1|AAG00867.1| 757|Homo sapiens tumor endothelial marke... 78 2e-14
AF003837-1|AAC51731.1| 1218|Homo sapiens Jagged1 protein. 78 2e-14
BC126986-1|AAI26987.1| 393|Homo sapiens FLJ37440 protein protein. 77 3e-14
X13916-1|CAA32112.1| 4544|Homo sapiens LDL-receptor related prec... 75 1e-13
DQ314873-1|ABC40732.1| 4544|Homo sapiens low density lipoprotein... 75 1e-13
AF058427-1|AAC64265.1| 4544|Homo sapiens lipoprotein receptor-re... 75 1e-13
AB209498-1|BAD92735.1| 2359|Homo sapiens low density lipoprotein... 75 1e-13
BC051836-1|AAH51836.2| 904|Homo sapiens low density lipoprotein... 75 2e-13
AL606760-4|CAI18908.1| 963|Homo sapiens low density lipoprotein... 75 2e-13
AL606760-2|CAI18910.1| 904|Homo sapiens low density lipoprotein... 75 2e-13
AL355483-3|CAI22781.1| 963|Homo sapiens low density lipoprotein... 75 2e-13
AL355483-1|CAI22780.1| 904|Homo sapiens low density lipoprotein... 75 2e-13
AY358892-1|AAQ89251.1| 723|Homo sapiens DLL1 protein. 75 2e-13
AL078605-2|CAB89569.1| 723|Homo sapiens delta-like 1 (Drosophil... 75 2e-13
AK074062-1|BAB84888.1| 1282|Homo sapiens FLJ00133 protein protein. 75 2e-13
AF222310-1|AAG09716.1| 723|Homo sapiens Delta1 protein. 75 2e-13
AF196571-1|AAF05834.1| 723|Homo sapiens Delta-like-1 protein pr... 75 2e-13
AF003522-1|AAB61286.1| 723|Homo sapiens Delta protein. 75 2e-13
S54426-1|AAB25244.1| 109|Homo sapiens fibrillin protein. 74 3e-13
D86407-1|BAA21824.1| 963|Homo sapiens ApoER2 protein. 74 3e-13
D50678-1|BAA09328.1| 963|Homo sapiens apolipoprotein E receptor... 74 3e-13
AF439717-1|AAQ04558.1| 1008|Homo sapiens insulin responsive sequ... 74 3e-13
L00352-1|AAA56833.1| 860|Homo sapiens low density lipoprotein r... 74 4e-13
BT007361-1|AAP36025.1| 860|Homo sapiens low density lipoprotein... 74 4e-13
BC014514-1|AAH14514.1| 860|Homo sapiens low density lipoprotein... 74 4e-13
AY324609-1|AAP72971.1| 860|Homo sapiens low density lipoprotein... 74 4e-13
AY114155-1|AAM56036.1| 860|Homo sapiens low density lipoprotein... 74 4e-13
AF217403-1|AAF24515.1| 837|Homo sapiens low density lipoprotein... 74 4e-13
AB209409-1|BAD92646.1| 870|Homo sapiens low density lipoprotein... 74 4e-13
BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosoph... 73 7e-13
AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein. 73 7e-13
AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellula... 73 7e-13
AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein. 73 7e-13
DQ470680-1|ABF06672.1| 373|Homo sapiens CRELD2-zeta protein. 73 9e-13
BC060770-1|AAH60770.2| 757|Homo sapiens SUSD1 protein protein. 72 1e-12
AY358746-1|AAQ89106.1| 747|Homo sapiens GRGP2438 protein. 72 1e-12
AL158824-3|CAI12348.2| 705|Homo sapiens sushi domain containing... 72 1e-12
AL158824-2|CAI12347.2| 747|Homo sapiens sushi domain containing... 72 1e-12
AL138756-2|CAI95300.2| 705|Homo sapiens sushi domain containing... 72 1e-12
AL138756-1|CAI95299.2| 747|Homo sapiens sushi domain containing... 72 1e-12
U33837-1|AAB41649.1| 4655|Homo sapiens gp330 precursor protein. 72 2e-12
U04441-1|AAB02882.1| 1751|Homo sapiens glycoprotein 330 protein. 72 2e-12
AY265358-1|AAP88586.1| 4655|Homo sapiens glycoprotein receptor g... 72 2e-12
AY265357-1|AAP88585.1| 4655|Homo sapiens glycoprotein receptor g... 72 2e-12
AC007556-2|AAX88965.1| 3881|Homo sapiens unknown protein. 72 2e-12
BC146761-1|AAI46762.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 71 2e-12
BC077719-1|AAH77719.1| 219|Homo sapiens VWCE protein protein. 71 2e-12
BC052564-1|AAH52564.1| 219|Homo sapiens VWCE protein protein. 71 2e-12
BC042143-1|AAH42143.1| 237|Homo sapiens VWCE protein protein. 71 2e-12
AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 71 2e-12
AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 71 2e-12
AL442123-4|CAH70918.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 71 2e-12
AL442123-3|CAH70917.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 71 2e-12
AF283408-1|AAL38109.1| 1537|Homo sapiens candidate tumor suppres... 71 2e-12
AF176832-1|AAF70379.1| 4599|Homo sapiens low density lipoprotein... 71 2e-12
AC093039-1|AAX88911.1| 425|Homo sapiens unknown protein. 71 2e-12
AB209707-1|BAD92944.1| 1720|Homo sapiens low density lipoprotein... 71 2e-12
AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein. 71 2e-12
AB209121-1|BAD92358.1| 620|Homo sapiens Mutant p53 binding prot... 71 4e-12
AL513325-3|CAM17208.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 70 5e-12
AL139136-3|CAM21656.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 70 5e-12
AL136322-4|CAM23328.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 70 5e-12
AJ748821-1|CAG38658.1| 1294|Homo sapiens crumbs homologue 1 (alt... 70 5e-12
DQ470679-1|ABF06671.1| 402|Homo sapiens CRELD2-epsilon protein. 70 6e-12
DQ470678-1|ABF06670.1| 353|Homo sapiens CRELD2-delta protein. 70 6e-12
AY358355-1|AAQ88721.1| 353|Homo sapiens RLPR185 protein. 70 6e-12
AL671710-6|CAO72067.1| 353|Homo sapiens cysteine-rich with EGF-... 70 6e-12
AL671710-5|CAO72066.1| 402|Homo sapiens cysteine-rich with EGF-... 70 6e-12
BX537434-1|CAD97676.1| 236|Homo sapiens hypothetical protein pr... 69 8e-12
BC084572-1|AAH84572.1| 343|Homo sapiens NOTCH2NL protein protein. 69 8e-12
BC010154-1|AAH10154.3| 236|Homo sapiens Notch homolog 2 (Drosop... 69 8e-12
AL592307-2|CAH73994.1| 230|Homo sapiens Notch homolog 2 (Drosop... 69 8e-12
AL592307-1|CAH73993.1| 236|Homo sapiens Notch homolog 2 (Drosop... 69 8e-12
AK075065-1|BAC11381.1| 269|Homo sapiens protein ( Homo sapiens ... 69 8e-12
AF283342-1|AAL38107.1| 881|Homo sapiens candidate tumor suppres... 69 8e-12
AC068287-1|AAY24318.1| 223|Homo sapiens unknown protein. 69 8e-12
AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein. 69 8e-12
DQ470676-1|ABF06668.1| 321|Homo sapiens CRELD2-alpha protein. 69 1e-11
BC002894-1|AAH02894.1| 321|Homo sapiens CRELD2 protein protein. 69 1e-11
AL671710-4|CAO72069.1| 321|Homo sapiens cysteine-rich with EGF-... 69 1e-11
AK074051-1|BAB84877.1| 1736|Homo sapiens FLJ00122 protein protein. 69 1e-11
BC090943-1|AAH90943.1| 249|Homo sapiens NOTCH2NL protein protein. 69 1e-11
BC065219-1|AAH65219.2| 236|Homo sapiens Notch homolog 2 (Drosop... 69 1e-11
BC019835-1|AAH19835.1| 236|Homo sapiens Notch homolog 2 N-termi... 69 1e-11
BC050675-1|AAH50675.1| 353|Homo sapiens cysteine-rich with EGF-... 68 2e-11
X84700-1|CAA59173.1| 742|Homo sapiens leucocyte antigen CD97 pr... 68 3e-11
BC026690-1|AAH26690.1| 742|Homo sapiens CD97 molecule protein. 68 3e-11
S73849-1|AAB31735.1| 873|Homo sapiens very low density lipoprot... 67 3e-11
L22431-1|AAA61344.1| 873|Homo sapiens very low density lipoprot... 67 3e-11
D16532-1|BAA03969.1| 873|Homo sapiens very low density lipoprot... 67 3e-11
D16494-1|BAA03946.1| 845|Homo sapiens very low density lipoprot... 67 3e-11
D16493-1|BAA03945.1| 873|Homo sapiens very low density lipoprot... 67 3e-11
DQ067198-1|AAY46157.1| 873|Homo sapiens very low density lipopr... 67 3e-11
CR457380-1|CAG33661.1| 422|Homo sapiens CRELD1 protein. 67 3e-11
BC146759-1|AAI46760.1| 1523|Homo sapiens slit homolog 3 (Drosoph... 67 3e-11
BC142653-1|AAI42654.1| 845|Homo sapiens very low density lipopr... 67 3e-11
AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein. 67 3e-11
AL450467-4|CAH72453.1| 752|Homo sapiens very low density lipopr... 67 3e-11
AL450467-3|CAH72455.1| 845|Homo sapiens very low density lipopr... 67 3e-11
AL450467-2|CAH72454.1| 873|Homo sapiens very low density lipopr... 67 3e-11
AK092381-1|BAC03874.1| 752|Homo sapiens protein ( Homo sapiens ... 67 3e-11
AF075240-1|AAD19336.1| 850|Homo sapiens SLIT1 protein protein. 67 3e-11
AB208822-1|BAD92059.1| 555|Homo sapiens Very low-density lipopr... 67 3e-11
AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein. 67 3e-11
AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein. 67 3e-11
BC008720-1|AAH08720.1| 422|Homo sapiens cysteine-rich with EGF-... 67 4e-11
AY358363-1|AAQ88729.1| 420|Homo sapiens CRELD1 protein. 67 4e-11
AF452623-1|AAM75206.1| 420|Homo sapiens cysteine-rich with EGF-... 67 4e-11
AY311388-1|AAP74958.1| 2551|Homo sapiens FEX2 protein. 66 8e-11
AY227444-1|AAO39681.1| 1416|Homo sapiens hyaluronan receptor for... 66 8e-11
AK024503-1|BAB15793.1| 1192|Homo sapiens FLJ00112 protein protein. 66 8e-11
AJ295695-1|CAC82105.1| 2551|Homo sapiens stabilin-2 protein. 66 8e-11
AF160476-1|AAF82398.1| 897|Homo sapiens CD44-like precursor FEL... 66 8e-11
AB052958-1|BAC15608.1| 2551|Homo sapiens FELE-2 protein. 66 8e-11
AL606760-3|CAI18909.1| 700|Homo sapiens low density lipoprotein... 66 1e-10
AL355483-2|CAI22782.1| 700|Homo sapiens low density lipoprotein... 66 1e-10
L20470-1|AAA53684.1| 873|Homo sapiens very low density lipoprot... 65 2e-10
D87433-1|BAA13377.2| 2589|Homo sapiens KIAA0246 protein protein. 65 2e-10
DQ786774-1|ABG91068.1| 2570|Homo sapiens FEX1 protein. 65 2e-10
BC150250-1|AAI50251.1| 2570|Homo sapiens stabilin 1 protein. 65 2e-10
AJ275213-1|CAB61827.1| 2570|Homo sapiens stabilin-1 protein. 65 2e-10
AB052956-1|BAC15606.1| 2570|Homo sapiens FELE-1 protein. 65 2e-10
Z75190-1|CAA99509.1| 699|Homo sapiens apolipoprotein E receptor... 64 3e-10
D86407-2|BAA21825.1| 793|Homo sapiens ApoER2delta4-7 protein. 64 4e-10
D63395-1|BAA09708.1| 1095|Homo sapiens notch related protein pro... 63 5e-10
BC072015-1|AAH72015.1| 296|Homo sapiens LRP1 protein protein. 63 5e-10
BC052593-1|AAH52593.1| 296|Homo sapiens LRP1 protein protein. 63 5e-10
BC045107-1|AAH45107.1| 292|Homo sapiens LRP1 protein protein. 63 5e-10
BC021204-1|AAH21204.1| 439|Homo sapiens LRP1 protein protein. 63 5e-10
BC038242-1|AAH38242.1| 261|Homo sapiens Similar to RIKEN cDNA 1... 63 7e-10
AY358347-1|AAQ88713.1| 406|Homo sapiens VPPP1921 protein. 63 7e-10
AY356402-1|AAR13653.1| 3222|Homo sapiens fat-like cadherin FATJ ... 63 7e-10
AB075863-1|BAB85569.1| 418|Homo sapiens KIAA1983 protein protein. 63 7e-10
BC106950-1|AAI06951.1| 685|Homo sapiens delta-like 4 (Drosophil... 61 3e-09
AY358894-1|AAQ89253.1| 685|Homo sapiens DLL4 protein. 61 3e-09
AF279305-1|AAF81912.1| 653|Homo sapiens delta 4 protein. 61 3e-09
AF253468-1|AAF76427.1| 685|Homo sapiens notch ligand DLL4 protein. 61 3e-09
AC068195-1|AAX93243.1| 1126|Homo sapiens unknown protein. 61 3e-09
AB043894-1|BAB18581.1| 685|Homo sapiens Delta-4 protein. 61 3e-09
AB036931-1|BAB16085.1| 685|Homo sapiens notch ligand delta-2 pr... 61 3e-09
BC024766-1|AAH24766.2| 454|Homo sapiens DNER protein protein. 59 9e-09
AY358891-1|AAQ89250.1| 737|Homo sapiens QPRR262 protein. 59 9e-09
AF442487-1|AAM21557.1| 737|Homo sapiens delta-notch-like EGF re... 59 9e-09
AC008273-1|AAF19247.2| 291|Homo sapiens unknown protein. 59 9e-09
BC141811-1|AAI41812.1| 540|Homo sapiens matrilin 4 protein. 58 2e-08
BC035009-1|AAH35009.1| 737|Homo sapiens delta/notch-like EGF re... 58 2e-08
AK074597-1|BAC11083.1| 540|Homo sapiens protein ( Homo sapiens ... 58 2e-08
AK074595-1|BAC11081.1| 488|Homo sapiens protein ( Homo sapiens ... 58 2e-08
AC019195-1|AAY14953.1| 546|Homo sapiens unknown protein. 58 2e-08
X55077-1|CAA38905.1| 591|Homo sapiens alpha-2 macroglobulin rec... 58 2e-08
AK160380-1|BAD18723.1| 1055|Homo sapiens FLJ00344 protein protein. 58 2e-08
AB033063-1|BAA86551.2| 1268|Homo sapiens KIAA1237 protein protein. 58 2e-08
U77914-1|AAC50909.1| 263|Homo sapiens soluble protein Jagged pr... 58 3e-08
DQ470677-1|ABF06669.1| 325|Homo sapiens CRELD2-gamma protein. 58 3e-08
BC000218-1|AAH00218.1| 618|Homo sapiens delta-like 3 (Drosophil... 58 3e-08
AL671710-3|CAO72068.1| 325|Homo sapiens cysteine-rich with EGF-... 58 3e-08
AF241373-1|AAF62542.1| 618|Homo sapiens DLL3 protein precursor ... 58 3e-08
AL137311-1|CAB70690.1| 252|Homo sapiens hypothetical protein pr... 57 4e-08
BC027939-1|AAH27939.1| 600|Homo sapiens SNED1 protein protein. 57 5e-08
AK075302-1|BAC11535.1| 587|Homo sapiens protein ( Homo sapiens ... 57 5e-08
Z12172-1|CAA78163.1| 383|Homo sapiens putative homeotic protein... 56 1e-07
X71923-1|CAA50739.1| 750|Homo sapiens tenascin-X precursor prot... 56 1e-07
U89337-3|AAB47488.1| 4289|Homo sapiens tenascin X protein. 56 1e-07
U15981-1|AAA75365.1| 310|Homo sapiens dlk protein. 56 1e-07
U15979-1|AAA75364.1| 382|Homo sapiens dlk protein. 56 1e-07
DQ126100-1|AAZ38943.1| 212|Homo sapiens brevideltin protein. 56 1e-07
DQ017081-1|AAY40461.1| 315|Homo sapiens secredeltin protein. 56 1e-07
BC014015-1|AAH14015.1| 383|Homo sapiens delta-like 1 homolog (D... 56 1e-07
BC013197-1|AAH13197.1| 383|Homo sapiens delta-like 1 homolog (D... 56 1e-07
BC007741-1|AAH07741.1| 383|Homo sapiens delta-like 1 homolog (D... 56 1e-07
AL772248-1|CAI18078.1| 4222|Homo sapiens tenascin XB protein. 56 1e-07
AL662884-1|CAI18332.1| 4222|Homo sapiens tenascin XB protein. 56 1e-07
AL662849-16|CAI17471.1| 4222|Homo sapiens tenascin XB protein. 56 1e-07
AL662828-1|CAI17414.1| 4222|Homo sapiens tenascin XB protein. 56 1e-07
AL645922-1|CAI41718.1| 4222|Homo sapiens tenascin XB protein. 56 1e-07
AL049547-2|CAB89296.1| 4288|Homo sapiens dJ34F7.1.1 (tenascin XB... 56 1e-07
X87241-1|CAA60685.1| 4590|Homo sapiens homologue of Drosophila F... 55 1e-07
AL450324-2|CAI13283.1| 186|Homo sapiens protein ( Human DNA seq... 55 1e-07
M59303-1|AAA36499.1| 320|Homo sapiens protein Z protein. 55 2e-07
M55671-1|AAA36501.1| 422|Homo sapiens protein Z protein. 55 2e-07
M55670-1|AAA36500.1| 400|Homo sapiens protein Z protein. 55 2e-07
BC110320-1|AAI10321.1| 383|Homo sapiens delta-like 2 homolog (D... 55 2e-07
BC074907-1|AAH74907.1| 400|Homo sapiens protein Z, vitamin K-de... 55 2e-07
BC074906-1|AAH74906.1| 400|Homo sapiens protein Z, vitamin K-de... 55 2e-07
AY358126-1|AAQ88493.1| 383|Homo sapiens PSGC2903 protein. 55 2e-07
AL359813-9|CAI23224.1| 383|Homo sapiens EGF-like-domain, multip... 55 2e-07
AL359813-8|CAI23223.1| 377|Homo sapiens EGF-like-domain, multip... 55 2e-07
AL137002-16|CAI41388.1| 400|Homo sapiens protein Z, vitamin K-d... 55 2e-07
AL137002-15|CAI41389.1| 422|Homo sapiens protein Z, vitamin K-d... 55 2e-07
AF440358-1|AAL27631.1| 400|Homo sapiens protein Z, vitamin K-de... 55 2e-07
AB033749-2|BAA85764.1| 422|Homo sapiens protein Z spliced varia... 55 2e-07
AB033749-1|BAA85763.1| 400|Homo sapiens protein Z protein. 55 2e-07
L38969-1|AAC41762.1| 956|Homo sapiens thrombospondin 3 protein. 54 3e-07
BC113847-1|AAI13848.1| 956|Homo sapiens thrombospondin 3, precu... 54 3e-07
AL713999-15|CAI95084.1| 956|Homo sapiens thrombospondin 3 protein. 54 3e-07
AK223278-1|BAD96998.1| 956|Homo sapiens thrombospondin 3 precur... 54 3e-07
AF023268-6|AAC51818.1| 736|Homo sapiens thrombospondin3 protein. 54 3e-07
BC088371-1|AAH88371.1| 273|Homo sapiens EGF-like-domain, multip... 54 3e-07
BC012377-1|AAH12377.1| 273|Homo sapiens EGF-like-domain, multip... 54 3e-07
AY358903-1|AAQ89262.1| 273|Homo sapiens VEMF protein. 54 3e-07
AY358902-1|AAQ89261.1| 273|Homo sapiens VEMF protein. 54 3e-07
AY358901-1|AAQ89260.1| 273|Homo sapiens VEMF protein. 54 3e-07
AL590226-1|CAH71721.1| 273|Homo sapiens EGF-like-domain, multip... 54 3e-07
AL031597-2|CAI23555.1| 3014|Homo sapiens cadherin, EGF LAG seven... 54 3e-07
AL031588-3|CAI19319.1| 3014|Homo sapiens cadherin, EGF LAG seven... 54 3e-07
AL021392-2|CAI20967.1| 3014|Homo sapiens cadherin, EGF LAG seven... 54 3e-07
AF231024-1|AAF61930.1| 3014|Homo sapiens protocadherin Flamingo ... 54 3e-07
AF186111-1|AAF01429.1| 273|Homo sapiens NOTCH4-like protein pro... 54 3e-07
AB125649-1|BAD01469.1| 273|Homo sapiens VE-statin protein. 54 3e-07
X15998-1|CAA34128.1| 2409|Homo sapiens protein ( H.sapiens mRNA ... 53 8e-07
U26555-1|AAA67565.1| 1642|Homo sapiens versican V2 core protein ... 53 8e-07
U16306-1|AAA65018.1| 3396|Homo sapiens chondroitin sulfate prote... 53 8e-07
J02814-1|AAA36437.1| 688|Homo sapiens protein ( Human chondroit... 53 8e-07
D32039-1|BAA06801.1| 655|Homo sapiens proteoglycan PG-M(V3) pro... 53 8e-07
BX641036-1|CAE46022.1| 2060|Homo sapiens hypothetical protein pr... 53 8e-07
AL359813-6|CAI23221.1| 288|Homo sapiens EGF-like-domain, multip... 53 8e-07
AB209491-1|BAD92728.1| 3410|Homo sapiens chondroitin sulfate pro... 53 8e-07
AB076400-1|BAB86868.1| 1097|Homo sapiens fat3 protein. 53 8e-07
D87469-1|BAA13407.2| 2854|Homo sapiens KIAA0279 protein protein. 52 1e-06
>AB209735-1|BAD92972.1| 1976|Homo sapiens fibrillin 2 (congenital
contractural arachnodactyly) variant protein.
Length = 1976
Score = 200 bits (489), Expect = 2e-51
Identities = 85/180 (47%), Positives = 107/180 (59%), Gaps = 3/180 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRP--AGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+NT+GSFRC C GY +G DEC+ P PC+ +C NT+GSY C C GY L E
Sbjct: 1530 INTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQE 1589
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINEC-HEEGVCPSP 359
DG C+D+DEC+ H CQ +C NT G + C C G+ + AC+D NEC + +C +
Sbjct: 1590 DGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAK 1649
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVR 539
G C N GSF C C RG+ LDA G C D DEC RCQ C+N GGYRC CP G ++
Sbjct: 1650 GICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHGCQNILGGYRCGCPQGYIQ 1709
Score = 163 bits (395), Expect = 5e-40
Identities = 76/186 (40%), Positives = 96/186 (51%), Gaps = 5/186 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDE 182
VNT+G F C C PG+ +EC +P C +C NT GS+ C C+ G+ LD
Sbjct: 1612 VNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDA 1671
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK--RGDACVDINECHEEGVCPS 356
G NC DVDEC+ + H CQ C N G Y C C GY + + + CVD NEC C S
Sbjct: 1672 TGLNCEDVDECDGN-HRCQHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGS 1730
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQT-GRCQAPCRNYAGGYRCDCPVGT 533
C N LGS++C CP G+ D + C D +EC+ + C C N GGY C CP G
Sbjct: 1731 AS-CYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYGCSNTEGGYLCGCPPGY 1789
Query: 534 VRSPSG 551
R G
Sbjct: 1790 YRVGQG 1795
Score = 151 bits (366), Expect = 2e-36
Identities = 79/190 (41%), Positives = 102/190 (53%), Gaps = 10/190 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD- 179
NTIGSF+C C G+ R DEC + P C +C NT GS++C C GYE
Sbjct: 155 NTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGF 214
Query: 180 EDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYE---KRGDACVDINECH-EEG 344
NC D+DECER+ C+ C NTEGS++C C G+E R D CVDINEC +
Sbjct: 215 MMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSRED-CVDINECSLSDN 273
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRCDC 521
+C + G+CVN++G+++C C GY+ + C D DEC G C C N G Y C C
Sbjct: 274 LCRN-GKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSC 332
Query: 522 PVGTVRSPSG 551
G P G
Sbjct: 333 SEGYALMPDG 342
Score = 149 bits (360), Expect = 8e-36
Identities = 73/185 (39%), Positives = 94/185 (50%), Gaps = 9/185 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN IG+++C C PGY+ P +G DEC + CD C N++GSY+C C GY L
Sbjct: 281 VNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMP 340
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECH-EEGVC 350
DG +C D+DECE + C C+N G Y C C DG+ D C+D+NEC +C
Sbjct: 341 DGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNIC 400
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC---AQTGRCQAPCRNYAGGYRCDC 521
G C N GSF C C GY + C D DEC A A C N G ++C C
Sbjct: 401 MF-GECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSC 459
Query: 522 PVGTV 536
G +
Sbjct: 460 REGWI 464
Score = 149 bits (360), Expect = 8e-36
Identities = 81/190 (42%), Positives = 104/190 (54%), Gaps = 9/190 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+NT GSFRC C GY GVR DEC++ P + C N GS++C C G+E
Sbjct: 1252 INTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFECNCNEGFE-PG 1310
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGV--C 350
NC D++EC ++ C C NT GSYEC+C GY R D C D++EC EG+ C
Sbjct: 1311 PMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKDLDEC-AEGLHDC 1369
Query: 351 PSPGR-CVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQ-APCRNYAGGYRCDC 521
S G C NL+G+F C+CP G +G CVD +EC + G C+ C N G YRC+C
Sbjct: 1370 ESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCEC 1429
Query: 522 PVGTVRSPSG 551
G S SG
Sbjct: 1430 NEGFQSSSSG 1439
Score = 142 bits (343), Expect = 1e-33
Identities = 74/187 (39%), Positives = 93/187 (49%), Gaps = 6/187 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDE 182
+N GSF+C C G+ G DEC+ C + C NT GSY C C G+
Sbjct: 449 LNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFT--G 506
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCP 353
DG C DVDEC + + C+ C N G+Y C CE G+ D+ C DI+EC + +C
Sbjct: 507 DGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICV 566
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPVG 530
G C NL G F C+C GY LD G C D DECA C C N G Y C+CP
Sbjct: 567 F-GTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPD 625
Query: 531 TVRSPSG 551
+P+G
Sbjct: 626 FQLNPTG 632
Score = 140 bits (339), Expect = 3e-33
Identities = 72/173 (41%), Positives = 92/173 (53%), Gaps = 7/173 (4%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C GPGY GR + DEC V P C C NT GS+ C C+ GY D G +C D+D
Sbjct: 1501 CPHGPGYTTDGRDI---DECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLD 1557
Query: 210 ECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINECH-EEGVCPSPGRCVNLL 380
EC + C IC NTEGSY+CSC GY ++ G C D++EC ++ C CVN L
Sbjct: 1558 ECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQF--LCVNTL 1615
Query: 381 GSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQAP--CRNYAGGYRCDCPVG 530
G F C CP G+ C+D +EC +Q C A C+N G + C+C G
Sbjct: 1616 GGFTCKCPPGF--TQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRG 1666
Score = 137 bits (332), Expect = 2e-32
Identities = 76/189 (40%), Positives = 102/189 (53%), Gaps = 8/189 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDED 185
V+ GS++C+C G++ + D PC C NT GSY+CLC G+EL +
Sbjct: 973 VDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGFELTHN 1032
Query: 186 GANCRDVDECER-DTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHE-EGVC 350
+C D+DEC C+ C N GS++C C +GYE D C+D NEC G C
Sbjct: 1033 N-DCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSC 1091
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQ-APCRNYAGGYRCDCP 524
SPG C NL GSFRC+CP GY + +E C+D +EC + C C N GG++C CP
Sbjct: 1092 -SPGTCQNLEGSFRCICPPGYEVKSE--NCIDINECDEDPNICLFGSCTNTPGGFQCLCP 1148
Query: 525 VGTVRSPSG 551
G V S +G
Sbjct: 1149 PGFVLSDNG 1157
Score = 137 bits (332), Expect = 2e-32
Identities = 64/152 (42%), Positives = 85/152 (55%), Gaps = 7/152 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGR-GVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
N IGSF C C G+ P +ECA P C C NT GSY+C C GY L ED
Sbjct: 1294 NVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQ 1353
Query: 189 ANCRDVDECERDTHTCQQ---ICSNTEGSYECSCEDGYEKR--GDACVDINECHEE-GVC 350
C+D+DEC H C+ +C N G++ C C G +R G+ CVD NEC + G+C
Sbjct: 1354 KMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGIC 1413
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
+ GRCVN++GS+RC C G++ + G C+D
Sbjct: 1414 EN-GRCVNIIGSYRCECNEGFQSSSSGTECLD 1444
Score = 131 bits (316), Expect = 2e-30
Identities = 65/181 (35%), Positives = 91/181 (50%), Gaps = 7/181 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELD 179
VNT GSF+C C G+ P+ +EC++ C + C N G+Y C C GY+
Sbjct: 239 VNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQAT 298
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCP 353
D C D+DEC C C+N+EGSYECSC +GY G +C DI+EC
Sbjct: 299 PDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDIC 358
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQ-APCRNYAGGYRCDCPV 527
G+C N+ G +RC+C G+ + C+D +EC + C C N G + C C +
Sbjct: 359 DGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQL 418
Query: 528 G 530
G
Sbjct: 419 G 419
Score = 130 bits (315), Expect = 2e-30
Identities = 68/179 (37%), Positives = 89/179 (49%), Gaps = 9/179 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA-GRGVRGRDECA-VRPPPC-DQLCHNTDGSYDCLCRTGYELDE 182
NT+GS+ C+C PG+ DEC+ C + C N GS+ CLC GYEL
Sbjct: 1014 NTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTP 1073
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSP 359
DG NC D +EC +C C N EGS+ C C GYE + + C+DINEC E+
Sbjct: 1074 DGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSENCIDINECDEDPNICLF 1133
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE--C---AQTGRCQAPCRNYAGGYRCDC 521
G C N G F+C+CP G+ L G RC D + C + G+C P +C C
Sbjct: 1134 GSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCC 1192
Score = 130 bits (313), Expect = 4e-30
Identities = 66/181 (36%), Positives = 93/181 (51%), Gaps = 8/181 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPPCD-QLCHNTDGSYDCLCRTGYELDE 182
N G +RC+C G+ + + +EC + C C NT GS+ C C+ GY + +
Sbjct: 365 NIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKK 424
Query: 183 DGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACVDINEC-HEEGVCP 353
C DVDECE H C C N GS++CSC +G+ G C+D++EC + C
Sbjct: 425 GTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCS 484
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQT-GRCQ-APCRNYAGGYRCDCPV 527
+CVN GS+RC C G+ +G C D DECA+ C+ C N G YRC+C +
Sbjct: 485 INAQCVNTPGSYRCACSEGF--TGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEM 542
Query: 528 G 530
G
Sbjct: 543 G 543
Score = 130 bits (313), Expect = 4e-30
Identities = 70/180 (38%), Positives = 88/180 (48%), Gaps = 7/180 (3%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGR-DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDV 206
C G G P+ R +EC P C C NTDGS+ C C GY LD G C D
Sbjct: 1219 CPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDT 1278
Query: 207 DECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CVDINECHEEGVCPSPGRCVNLLG 383
DEC C+N GS+EC+C +G+E C DINEC + + RC+N G
Sbjct: 1279 DECSIGNPCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLL-CAFRCMNTFG 1337
Query: 384 SFRCVCPRGYRLDAEGARCVDRDECAQ-TGRCQA---PCRNYAGGYRCDCPVGTVRSPSG 551
S+ C CP GY L + C D DECA+ C++ C+N G + C CP G R P G
Sbjct: 1338 SYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDG 1397
Score = 129 bits (312), Expect = 6e-30
Identities = 66/180 (36%), Positives = 91/180 (50%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT GS++C C GY + G+ + DEC + C LC NT G + C C G+ +
Sbjct: 1572 NTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFT--QH 1629
Query: 186 GANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGY--EKRGDACVDINECHEEGVCP 353
C D +EC C + IC NT GS+ C C+ G+ + G C D++EC C
Sbjct: 1630 HTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQ 1689
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPVG 530
C N+LG +RC CP+GY + +CVD +EC+ C A C N G Y+C CP G
Sbjct: 1690 HG--CQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSG 1747
Score = 129 bits (311), Expect = 7e-30
Identities = 70/184 (38%), Positives = 91/184 (49%), Gaps = 13/184 (7%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGR------DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGA 191
C G G+ G + GR +EC P C C NT GS+ C C +G+ LD +
Sbjct: 116 CPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEER 175
Query: 192 NCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEK---RGDACVDINECHEEGVCPSP 359
NC D+DEC C IC NT GS+EC C +GYE C+DI+EC +
Sbjct: 176 NCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRG 235
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQ-APCRNYAGGYRCDCPVGT 533
G CVN GSF+C CP G+ L CVD +EC+ + C+ C N G Y+C C G
Sbjct: 236 GTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGY 295
Query: 534 VRSP 545
+P
Sbjct: 296 QATP 299
Score = 129 bits (311), Expect = 7e-30
Identities = 68/181 (37%), Positives = 91/181 (50%), Gaps = 8/181 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELD 179
NT GSF C C GY + G DEC + CD C N GS+ C CR G+
Sbjct: 407 NTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWI-- 464
Query: 180 EDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRGDACVDINECHEE-GVC 350
+G C D+DEC TH C C NT GSY C+C +G+ G C D++EC E +C
Sbjct: 465 GNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAENINLC 524
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ-APCRNYAGGYRCDCPV 527
+ G+C+N+ G++RC C G+ ++ C D DEC+ C C N G + C C
Sbjct: 525 EN-GQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDD 583
Query: 528 G 530
G
Sbjct: 584 G 584
Score = 126 bits (303), Expect = 7e-29
Identities = 72/188 (38%), Positives = 90/188 (47%), Gaps = 10/188 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA---GRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYEL 176
VNT GSF C C GY + DEC P C C NT+GS+ C C G+EL
Sbjct: 196 VNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHEL 255
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECH-EEG 344
+C D++EC + C+ C N G+Y+CSC GY+ D C DI+EC G
Sbjct: 256 SPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNG 315
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQT-GRCQ-APCRNYAGGYRCD 518
C + +C N GS+ C C GY L +G C D DEC C C N G YRC
Sbjct: 316 GCDT--QCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCL 373
Query: 519 CPVGTVRS 542
C G + S
Sbjct: 374 CYDGFMAS 381
Score = 122 bits (293), Expect = 1e-27
Identities = 67/178 (37%), Positives = 93/178 (52%), Gaps = 10/178 (5%)
Frame = +3
Query: 27 FRCVCG--PGYR---PAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDEDG 188
F+ +CG PG+ G+ V DEC P C + +C N GS+ C C TG+ ++
Sbjct: 851 FKTICGNIPGFTFDIHTGKAV-DIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLL 909
Query: 189 ANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYE-KRGDACVDINECHE-EGVCPS 356
C D+DEC + CQ+ C N+ GSY C C G++ ACVD NEC E VC S
Sbjct: 910 LVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVC-S 968
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
G CV+L GS++C+C G++ + C+D DEC + C+N G Y C C G
Sbjct: 969 HGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPG 1026
Score = 118 bits (283), Expect = 2e-26
Identities = 57/149 (38%), Positives = 76/149 (51%), Gaps = 3/149 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDED 185
VNT GS+RC C G+ G DECA C+ C N G+Y C C G+ D
Sbjct: 490 VNTPGSYRCACSEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASD 549
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPSP 359
+C+D+DEC C+N G + C C+DGYE + G C DI+EC + C +
Sbjct: 550 SRSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVN- 608
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
G CVN G + C CP ++L+ G CVD
Sbjct: 609 GLCVNTPGRYECNCPPDFQLNPTGVGCVD 637
Score = 114 bits (275), Expect = 2e-25
Identities = 72/214 (33%), Positives = 93/214 (43%), Gaps = 34/214 (15%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
N IG+F C+C PG RP G G +EC +P C+ C N GSY C C G++
Sbjct: 1378 NLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSS 1437
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSY------ECSCEDG-----------------Y 293
G C D + Q IC S EC C+ G Y
Sbjct: 1438 SGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQY 1497
Query: 294 EK---RGDACV----DINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRD 452
+K G DI+EC + G+C+N +GSFRC C GY D G C+D D
Sbjct: 1498 KKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLD 1557
Query: 453 ECAQTGR-CQAPCRNYAGGYRCDCPVGTVRSPSG 551
EC+Q+ + C C+N G Y+C CP G V G
Sbjct: 1558 ECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDG 1591
Score = 113 bits (271), Expect = 5e-25
Identities = 68/191 (35%), Positives = 99/191 (51%), Gaps = 10/191 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPG--YRPAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYEL 176
+N IGSFRC C G Y DEC+ C + C N+ GSY C C G++L
Sbjct: 889 INQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKL 948
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGV 347
+GA C D +EC + C +C + +GSY+C C +G++ D C+D++EC E
Sbjct: 949 SPNGA-CVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDEC-ERHP 1006
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGR-CQ-APCRNYAGGYRCD 518
C + G C N +GS+ C+C G+ L C+D DEC+ G+ C+ C N G ++C
Sbjct: 1007 CGN-GTCKNTVGSYNCLCYPGFEL-THNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCL 1064
Query: 519 CPVGTVRSPSG 551
C G +P G
Sbjct: 1065 CNEGYELTPDG 1075
Score = 94.7 bits (225), Expect = 2e-19
Identities = 67/215 (31%), Positives = 93/215 (43%), Gaps = 41/215 (19%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+N G++RC C G+ PA R + DEC+ + C+N G + C+C GYELD
Sbjct: 530 LNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELDR 589
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVD--INECH----- 335
G NC D+DEC + +C NT G YEC+C ++ G CVD + C+
Sbjct: 590 TGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGP 649
Query: 336 ----------EEGVCPSPGRCVNLLG----------------SFRCVCP--RGYRLDAEG 431
E GV S C LG + +CP G+R +
Sbjct: 650 RGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPIT 709
Query: 432 ARCVDRDECAQ-TGRCQ-APCRNYAGGYRCDCPVG 530
D DEC + G CQ C N G ++C+CP G
Sbjct: 710 IILEDIDECQELPGLCQGGNCINTFGSFQCECPQG 744
Score = 93.5 bits (222), Expect = 4e-19
Identities = 66/215 (30%), Positives = 97/215 (45%), Gaps = 39/215 (18%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYE 173
R N IGSF+C+C GY P G+ +EC P C C N +GS+ C+C GYE
Sbjct: 1053 RCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYE 1112
Query: 174 LDEDGANCRDVDECERDTHTCQ-QICSNTEGSYECSCEDGY--EKRGDACVDINE--C-- 332
+ + NC D++EC+ D + C C+NT G ++C C G+ G C D + C
Sbjct: 1113 VKSE--NCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFT 1170
Query: 333 -HEEGVCPSPGR---------CVNLLG----------------SFRCVCPRGY-RLDAEG 431
E G C P C + G +F+ +CP G+ + +
Sbjct: 1171 NFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLH 1230
Query: 432 ARCVDRDECAQT-GRC-QAPCRNYAGGYRCDCPVG 530
D +EC ++ G C C N G +RC+CP+G
Sbjct: 1231 DTREDVNECLESPGICSNGQCINTDGSFRCECPMG 1265
Score = 89.8 bits (213), Expect = 5e-18
Identities = 58/183 (31%), Positives = 79/183 (43%), Gaps = 5/183 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
NT G F+C+C PG+ + G R D C + C + +
Sbjct: 1138 NTPGGFQCLCPPGFVLSDNGRRCFDTR-------QSFCFTNFENGKCSVPKAFNTTKAKC 1190
Query: 192 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGY---EKRGDACVDINECHEE-GVCPSP 359
C + E C+ + E +++ C G+ D D+NEC E G+C S
Sbjct: 1191 CCSKMPG-EGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGIC-SN 1248
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPVGTV 536
G+C+N GSFRC CP GY LD G RCVD DEC+ C C N G + C+C G
Sbjct: 1249 GQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFECNCNEGFE 1308
Query: 537 RSP 545
P
Sbjct: 1309 PGP 1311
Score = 85.4 bits (202), Expect = 1e-16
Identities = 52/148 (35%), Positives = 63/148 (42%), Gaps = 4/148 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT GSF C C G+ G+ D EC C C N G Y C C GY
Sbjct: 1654 NTPGSFSCECQRGFSLDATGLNCEDVDECDGNHR-CQHGCQNILGGYRCGCPQGYIQHYQ 1712
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCPSP 359
C D +EC C NT GSY+C+C G +++ AC D+NEC P
Sbjct: 1713 WNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNEC-SSSKNPCN 1771
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCV 443
C N G + C CP GY +G CV
Sbjct: 1772 YGCSNTEGGYLCGCPPGYYRVGQG-HCV 1798
Score = 82.6 bits (195), Expect = 8e-16
Identities = 60/181 (33%), Positives = 78/181 (43%), Gaps = 9/181 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRG-VRGR-DECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
VNT G + C C P ++ P G G V R C ++ P DGS C G +
Sbjct: 612 VNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGP------RGDGSLSCNTEIGVGV 665
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV--DINECHE-EGV 347
C TC + ++TE C +G+ + DI+EC E G+
Sbjct: 666 SRSSCCCSLGKAWGNPCETCPPV-NSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGL 724
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC-QAPCRNYAGGYRCDC 521
C G C+N GSF+C CP+GY L + C D DEC A G C C N G Y C C
Sbjct: 725 CQG-GNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCIC 783
Query: 522 P 524
P
Sbjct: 784 P 784
Score = 81.8 bits (193), Expect = 1e-15
Identities = 47/124 (37%), Positives = 64/124 (51%), Gaps = 7/124 (5%)
Frame = +3
Query: 198 RDVDECERDTHTCQQ-ICSNTEGSYECSCEDGY--EKRGDACVDINECH-EEGVCPSPGR 365
+D++EC+ C C NT GS++C C G+ + C DI+EC +C S G
Sbjct: 136 KDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGS-GI 194
Query: 366 CVNLLGSFRCVCPRGYRLDAEGAR-CVDRDECAQTGR-CQA-PCRNYAGGYRCDCPVGTV 536
CVN GSF C C GY + C+D DEC + C+ C N G ++CDCP+G
Sbjct: 195 CVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHE 254
Query: 537 RSPS 548
SPS
Sbjct: 255 LSPS 258
Score = 81.4 bits (192), Expect = 2e-15
Identities = 67/222 (30%), Positives = 89/222 (40%), Gaps = 41/222 (18%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD 179
+NT GSF+C C GY + R DEC P C C+NT G+Y C+C Y
Sbjct: 731 INTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQV 790
Query: 180 EDGANCRDVDE--CERDTH--TCQQICSNTEGSYECSCE----DGYEKRGDACVDINECH 335
G NC D+ + C R + TC+ C C + K + C
Sbjct: 791 NGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTAD 850
Query: 336 EEGVCPS----------------------PGRC-----VNLLGSFRCVCPRGYRLDAEGA 434
+ +C + PG C +N +GSFRC CP G+ +
Sbjct: 851 FKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLL 910
Query: 435 RCVDRDECAQ-TGRCQ--APCRNYAGGYRCDCPVGTVRSPSG 551
C D DEC+ CQ A C N G YRC+C G SP+G
Sbjct: 911 VCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNG 952
Score = 78.2 bits (184), Expect = 2e-14
Identities = 47/149 (31%), Positives = 65/149 (43%), Gaps = 13/149 (8%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCD---QLCHNTDGSYDCLCRTG 167
R +NT GS+ C C GY R + + DECA C+ +C N G++ C+C G
Sbjct: 1331 RCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPG 1390
Query: 168 YELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYE--KRGDACVDINE--C 332
DG C D +EC C+ C N GSY C C +G++ G C+D + C
Sbjct: 1391 MARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLC 1450
Query: 333 HEE---GVCPSPGRCVNLLGSFRCVCPRG 410
E +C NL+ C C G
Sbjct: 1451 FAEVLQTICQMASSSRNLVTKSECCCDGG 1479
Score = 74.5 bits (175), Expect = 2e-13
Identities = 43/119 (36%), Positives = 55/119 (46%), Gaps = 6/119 (5%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCR--TGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECS 278
PC+ Y LC G+ + D+DEC+ CQ C NT GS++C
Sbjct: 681 PCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCE 740
Query: 279 CEDGYEKRGDA--CVDINECHEE-GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
C GY D C DI+EC GVC PG C N LG++ C+CP Y G C+D
Sbjct: 741 CPQGYYLSEDTRICEDIDECFAHPGVC-GPGTCYNTLGNYTCICPPEYMQVNGGHNCMD 798
Score = 69.3 bits (162), Expect = 8e-12
Identities = 57/187 (30%), Positives = 76/187 (40%), Gaps = 41/187 (21%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDV--DEC--ERDTHTC---- 236
+EC V P C C N+ GS+ C C G LD G C D+ ++C + D C
Sbjct: 21 NECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPV 80
Query: 237 ------QQICSNTEGSYECSCED-----------------GYEKRGDACV------DINE 329
C ++ CE+ G+ RGD DINE
Sbjct: 81 PGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINE 140
Query: 330 CHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC-QAPCRNYA 500
C G+C + G+C N +GSF+C C G+ LD E C D DEC C C N
Sbjct: 141 CKAFPGMC-TYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTP 199
Query: 501 GGYRCDC 521
G + C+C
Sbjct: 200 GSFECEC 206
Score = 61.3 bits (142), Expect = 2e-09
Identities = 29/61 (47%), Positives = 36/61 (59%), Gaps = 2/61 (3%)
Frame = +3
Query: 270 ECSCEDGYEK-RGDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCV 443
+ +C G + +G C D+NEC GVCP+ GRCVN GSF C CP G LD G C+
Sbjct: 2 DTACPRGLARIKGVTCEDVNECEVFPGVCPN-GRCVNSKGSFHCECPEGLTLDGTGRVCL 60
Query: 444 D 446
D
Sbjct: 61 D 61
Score = 46.4 bits (105), Expect = 7e-05
Identities = 44/154 (28%), Positives = 63/154 (40%), Gaps = 39/154 (25%)
Frame = +3
Query: 186 GANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDG--YEKRGDACVDI--NECH----- 335
G C DV+ECE C C N++GS+ C C +G + G C+DI +C+
Sbjct: 14 GVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDE 73
Query: 336 EEGVCPSPGR-----CVNLLGS----------------FRCVCPRGYRLDAEGARCVDR- 449
+E + P PG+ C +G+ + +CPRG G R
Sbjct: 74 DECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRP 133
Query: 450 -----DEC-AQTGRC-QAPCRNYAGGYRCDCPVG 530
+EC A G C CRN G ++C C G
Sbjct: 134 FYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSG 167
Score = 35.1 bits (77), Expect = 0.17
Identities = 19/53 (35%), Positives = 24/53 (45%), Gaps = 2/53 (3%)
Frame = +3
Query: 399 CPRGYRLDAEGARCVDRDECAQ-TGRC-QAPCRNYAGGYRCDCPVGTVRSPSG 551
CPRG +G C D +EC G C C N G + C+CP G +G
Sbjct: 5 CPRGLAR-IKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTG 56
>U03272-1|AAA18950.1| 2911|Homo sapiens fibrillin-2 protein.
Length = 2911
Score = 199 bits (486), Expect = 5e-51
Identities = 85/180 (47%), Positives = 106/180 (58%), Gaps = 3/180 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRP--AGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+NT+GSFRC C GY +G DEC+ P PC+ +C NT+GSY C C GY L E
Sbjct: 2465 INTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQE 2524
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEG-VCPSP 359
DG C+D+DEC+ H CQ +C NT G + C C G+ + AC+D NEC + +C
Sbjct: 2525 DGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPLLCGGK 2584
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVR 539
G C N GSF C C RG+ LDA G C D DEC RCQ C+N GGYRC CP G ++
Sbjct: 2585 GICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHGCQNILGGYRCGCPQGYIQ 2644
Score = 161 bits (392), Expect = 1e-39
Identities = 76/186 (40%), Positives = 96/186 (51%), Gaps = 5/186 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDE 182
VNT+G F C C PG+ +EC +P C +C NT GS+ C C+ G+ LD
Sbjct: 2547 VNTLGGFTCKCPPGFTQHHTACIDNNECGSQPLLCGGKGICQNTPGSFSCECQRGFSLDA 2606
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK--RGDACVDINECHEEGVCPS 356
G NC DVDEC+ + H CQ C N G Y C C GY + + + CVD NEC C S
Sbjct: 2607 TGLNCEDVDECDGN-HRCQHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGS 2665
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQT-GRCQAPCRNYAGGYRCDCPVGT 533
C N LGS++C CP G+ D + C D +EC+ + C C N GGY C CP G
Sbjct: 2666 AS-CYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYGCSNTEGGYLCGCPPGY 2724
Query: 534 VRSPSG 551
R G
Sbjct: 2725 YRVGQG 2730
Score = 149 bits (361), Expect = 6e-36
Identities = 81/190 (42%), Positives = 104/190 (54%), Gaps = 9/190 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+NT GSFRC C GY GVR DEC++ P + C N GS++C C G+E
Sbjct: 2187 INTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFECNCNEGFE-PG 2245
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGV--C 350
NC D++EC ++ C C NT GSYEC+C GY R D C D++EC EG+ C
Sbjct: 2246 PMMNCEDINECAQNPLLCALRCMNTFGSYECTCPIGYALREDQKMCKDLDEC-AEGLHDC 2304
Query: 351 PSPGR-CVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQ-APCRNYAGGYRCDC 521
S G C NL+G+F C+CP G +G CVD +EC + G C+ C N G YRC+C
Sbjct: 2305 ESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCEC 2364
Query: 522 PVGTVRSPSG 551
G S SG
Sbjct: 2365 NEGFQSSSSG 2374
Score = 149 bits (360), Expect = 8e-36
Identities = 73/185 (39%), Positives = 94/185 (50%), Gaps = 9/185 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN IG+++C C PGY+ P +G DEC + CD C N++GSY+C C GY L
Sbjct: 1216 VNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMP 1275
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECH-EEGVC 350
DG +C D+DECE + C C+N G Y C C DG+ D C+D+NEC +C
Sbjct: 1276 DGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNIC 1335
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC---AQTGRCQAPCRNYAGGYRCDC 521
G C N GSF C C GY + C D DEC A A C N G ++C C
Sbjct: 1336 MF-GECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSC 1394
Query: 522 PVGTV 536
G +
Sbjct: 1395 REGWI 1399
Score = 148 bits (359), Expect = 1e-35
Identities = 78/190 (41%), Positives = 101/190 (53%), Gaps = 10/190 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD- 179
NTIGSF+C C G+ R DEC + P C +C NT GS++C C GYE
Sbjct: 1090 NTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGF 1149
Query: 180 EDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYE---KRGDACVDINECH-EEG 344
NC D+D CER+ C+ C NTEGS++C C G+E R D CVDINEC +
Sbjct: 1150 MMMKNCMDIDGCERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSRED-CVDINECSLSDN 1208
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRCDC 521
+C + G+CVN++G+++C C GY+ + C D DEC G C C N G Y C C
Sbjct: 1209 LCRN-GKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSC 1267
Query: 522 PVGTVRSPSG 551
G P G
Sbjct: 1268 SEGYALMPDG 1277
Score = 144 bits (349), Expect = 2e-34
Identities = 75/187 (40%), Positives = 94/187 (50%), Gaps = 6/187 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDE 182
+N GSF+C C G+ G DEC+ C + C NT GSY C C G+
Sbjct: 1384 LNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFT--G 1441
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCP 353
DG C DVDEC + + C+ C N G+Y C CE G+ D+ C DI+EC + +C
Sbjct: 1442 DGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICV 1501
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPVG 530
S G C NL G F C+C GY LD G C D DECA C C N G Y C+CP
Sbjct: 1502 S-GTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPD 1560
Query: 531 TVRSPSG 551
+P+G
Sbjct: 1561 FQLNPTG 1567
Score = 138 bits (333), Expect = 2e-32
Identities = 64/152 (42%), Positives = 85/152 (55%), Gaps = 7/152 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGR-GVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
N IGSF C C G+ P +ECA P C C NT GSY+C C GY L ED
Sbjct: 2229 NVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCALRCMNTFGSYECTCPIGYALREDQ 2288
Query: 189 ANCRDVDECERDTHTCQQ---ICSNTEGSYECSCEDGYEKR--GDACVDINECHEE-GVC 350
C+D+DEC H C+ +C N G++ C C G +R G+ CVD NEC + G+C
Sbjct: 2289 KMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGIC 2348
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
+ GRCVN++GS+RC C G++ + G C+D
Sbjct: 2349 EN-GRCVNIIGSYRCECNEGFQSSSSGTECLD 2379
Score = 137 bits (332), Expect = 2e-32
Identities = 70/181 (38%), Positives = 93/181 (51%), Gaps = 5/181 (2%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRG-VRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELD 179
R + T+ S+RC C GY+ G DEC P C NT GSY C C G++
Sbjct: 508 RCIPTVSSYRCECNMGYKQDANGDCIDVDECTSNPCTNGD-CVNTPGSYYCKCHAGFQRT 566
Query: 180 EDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVC 350
C D+DEC ++ C+ C N++GS++C C G+E D CVD +EC +C
Sbjct: 567 PTKQACIDIDECIQNGVLCKNGRCVNSDGSFQCICNAGFELTTDGKNCVDHDECTTTNMC 626
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPV 527
+ G C+N GSF+C+C G+ L G C D DEC G C C N G +RCDCP
Sbjct: 627 LN-GMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPP 685
Query: 528 G 530
G
Sbjct: 686 G 686
Score = 137 bits (332), Expect = 2e-32
Identities = 76/189 (40%), Positives = 102/189 (53%), Gaps = 8/189 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDED 185
V+ GS++C+C G++ + D PC C NT GSY+CLC G+EL +
Sbjct: 1908 VDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGFELTHN 1967
Query: 186 GANCRDVDECER-DTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHE-EGVC 350
+C D+DEC C+ C N GS++C C +GYE D C+D NEC G C
Sbjct: 1968 N-DCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSC 2026
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQ-APCRNYAGGYRCDCP 524
SPG C NL GSFRC+CP GY + +E C+D +EC + C C N GG++C CP
Sbjct: 2027 -SPGTCQNLEGSFRCICPPGYEVKSE--NCIDINECDEDPNICLFGSCTNTPGGFQCLCP 2083
Query: 525 VGTVRSPSG 551
G V S +G
Sbjct: 2084 PGFVLSDNG 2092
Score = 137 bits (332), Expect = 2e-32
Identities = 71/173 (41%), Positives = 92/173 (53%), Gaps = 7/173 (4%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C GPGY GR + DEC V P C C NT GS+ C C+ GY D G +C D+D
Sbjct: 2436 CPHGPGYTTDGRDI---DECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLD 2492
Query: 210 ECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINECH-EEGVCPSPGRCVNLL 380
EC + C IC NTEGSY+CSC GY ++ G C D++EC ++ C CVN L
Sbjct: 2493 ECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQF--LCVNTL 2550
Query: 381 GSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC--QAPCRNYAGGYRCDCPVG 530
G F C CP G+ C+D +EC +Q C + C+N G + C+C G
Sbjct: 2551 GGFTCKCPPGF--TQHHTACIDNNECGSQPLLCGGKGICQNTPGSFSCECQRG 2601
Score = 132 bits (320), Expect = 6e-31
Identities = 64/146 (43%), Positives = 82/146 (56%), Gaps = 3/146 (2%)
Frame = +3
Query: 123 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 302
C T SY C C GY+ D +G +C DVDEC + T C NT GSY C C G+++
Sbjct: 509 CIPTVSSYRCECNMGYKQDANG-DCIDVDECTSNPCTNGD-CVNTPGSYYCKCHAGFQRT 566
Query: 303 G--DACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC 476
AC+DI+EC + GV GRCVN GSF+C+C G+ L +G CVD DEC T C
Sbjct: 567 PTKQACIDIDECIQNGVLCKNGRCVNSDGSFQCICNAGFELTTDGKNCVDHDECTTTNMC 626
Query: 477 -QAPCRNYAGGYRCDCPVGTVRSPSG 551
C N G ++C C G V +P+G
Sbjct: 627 LNGMCINEDGSFKCICKPGFVLAPNG 652
Score = 131 bits (316), Expect = 2e-30
Identities = 65/181 (35%), Positives = 91/181 (50%), Gaps = 7/181 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELD 179
VNT GSF+C C G+ P+ +EC++ C + C N G+Y C C GY+
Sbjct: 1174 VNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQAT 1233
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCP 353
D C D+DEC C C+N+EGSYECSC +GY G +C DI+EC
Sbjct: 1234 PDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDIC 1293
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQ-APCRNYAGGYRCDCPV 527
G+C N+ G +RC+C G+ + C+D +EC + C C N G + C C +
Sbjct: 1294 DGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQL 1353
Query: 528 G 530
G
Sbjct: 1354 G 1354
Score = 130 bits (315), Expect = 2e-30
Identities = 68/179 (37%), Positives = 89/179 (49%), Gaps = 9/179 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA-GRGVRGRDECA-VRPPPC-DQLCHNTDGSYDCLCRTGYELDE 182
NT+GS+ C+C PG+ DEC+ C + C N GS+ CLC GYEL
Sbjct: 1949 NTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTP 2008
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSP 359
DG NC D +EC +C C N EGS+ C C GYE + + C+DINEC E+
Sbjct: 2009 DGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSENCIDINECDEDPNICLF 2068
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE--C---AQTGRCQAPCRNYAGGYRCDC 521
G C N G F+C+CP G+ L G RC D + C + G+C P +C C
Sbjct: 2069 GSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCC 2127
Score = 130 bits (313), Expect = 4e-30
Identities = 66/181 (36%), Positives = 93/181 (51%), Gaps = 8/181 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPPCD-QLCHNTDGSYDCLCRTGYELDE 182
N G +RC+C G+ + + +EC + C C NT GS+ C C+ GY + +
Sbjct: 1300 NIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKK 1359
Query: 183 DGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACVDINEC-HEEGVCP 353
C DVDECE H C C N GS++CSC +G+ G C+D++EC + C
Sbjct: 1360 GTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCS 1419
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQT-GRCQ-APCRNYAGGYRCDCPV 527
+CVN GS+RC C G+ +G C D DECA+ C+ C N G YRC+C +
Sbjct: 1420 INAQCVNTPGSYRCACSEGF--TGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEM 1477
Query: 528 G 530
G
Sbjct: 1478 G 1478
Score = 130 bits (313), Expect = 4e-30
Identities = 68/181 (37%), Positives = 91/181 (50%), Gaps = 8/181 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELD 179
NT GSF C C GY + G DEC + CD C N GS+ C CR G+
Sbjct: 1342 NTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWI-- 1399
Query: 180 EDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRGDACVDINECHEE-GVC 350
+G C D+DEC TH C C NT GSY C+C +G+ G C D++EC E +C
Sbjct: 1400 GNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAENINLC 1459
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPV 527
+ G+C+N+ G++RC C G+ ++ C D DEC+ C C N G + C C
Sbjct: 1460 EN-GQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVSGTCNNLPGMFHCICDD 1518
Query: 528 G 530
G
Sbjct: 1519 G 1519
Score = 130 bits (313), Expect = 4e-30
Identities = 70/180 (38%), Positives = 89/180 (49%), Gaps = 7/180 (3%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGR-DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDV 206
C G G P+ R +EC P C C NTDGS+ C C GY LD G C D
Sbjct: 2154 CPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDT 2213
Query: 207 DECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CVDINECHEEGVCPSPGRCVNLLG 383
DEC C+N GS+EC+C +G+E C DINEC + + + RC+N G
Sbjct: 2214 DECSIGNPCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAL-RCMNTFG 2272
Query: 384 SFRCVCPRGYRLDAEGARCVDRDECAQ-TGRCQA---PCRNYAGGYRCDCPVGTVRSPSG 551
S+ C CP GY L + C D DECA+ C++ C+N G + C CP G R P G
Sbjct: 2273 SYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDG 2332
Score = 128 bits (310), Expect = 1e-29
Identities = 66/180 (36%), Positives = 91/180 (50%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT GS++C C GY + G+ + DEC + C LC NT G + C C G+ +
Sbjct: 2507 NTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFT--QH 2564
Query: 186 GANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGY--EKRGDACVDINECHEEGVCP 353
C D +EC C + IC NT GS+ C C+ G+ + G C D++EC C
Sbjct: 2565 HTACIDNNECGSQPLLCGGKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQ 2624
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPVG 530
C N+LG +RC CP+GY + +CVD +EC+ C A C N G Y+C CP G
Sbjct: 2625 HG--CQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSG 2682
Score = 127 bits (306), Expect = 3e-29
Identities = 67/182 (36%), Positives = 89/182 (48%), Gaps = 11/182 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD 179
VNT GS+ C C G++ P + DEC C C N+DGS+ C+C G+EL
Sbjct: 549 VNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNSDGSFQCICNAGFELT 608
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINECHEEGVCP 353
DG NC D DEC +C N +GS++C C+ G+ G C D++EC G+C
Sbjct: 609 TDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGICM 668
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVD---RDEC---AQTGRCQAPCRNYAGGYRC 515
+ G C+N GSFRC CP G + +G CVD R C + G C P C
Sbjct: 669 N-GHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSEC 727
Query: 516 DC 521
C
Sbjct: 728 CC 729
Score = 126 bits (304), Expect = 5e-29
Identities = 69/184 (37%), Positives = 90/184 (48%), Gaps = 13/184 (7%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGR------DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGA 191
C G G+ G + GR +EC P C C NT GS+ C C +G+ LD +
Sbjct: 1051 CPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEER 1110
Query: 192 NCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEK---RGDACVDINECHEEGVCPSP 359
NC D+DEC C IC NT GS+EC C +GYE C+DI+ C +
Sbjct: 1111 NCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDGCERNPLLCRG 1170
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQ-APCRNYAGGYRCDCPVGT 533
G CVN GSF+C CP G+ L CVD +EC+ + C+ C N G Y+C C G
Sbjct: 1171 GTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGY 1230
Query: 534 VRSP 545
+P
Sbjct: 1231 QATP 1234
Score = 123 bits (296), Expect = 5e-28
Identities = 71/188 (37%), Positives = 89/188 (47%), Gaps = 10/188 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA---GRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYEL 176
VNT GSF C C GY + D C P C C NT+GS+ C C G+EL
Sbjct: 1131 VNTPGSFECECFEGYESGFMMMKNCMDIDGCERNPLLCRGGTCVNTEGSFQCDCPLGHEL 1190
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECH-EEG 344
+C D++EC + C+ C N G+Y+CSC GY+ D C DI+EC G
Sbjct: 1191 SPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNG 1250
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQT-GRCQ-APCRNYAGGYRCD 518
C + +C N GS+ C C GY L +G C D DEC C C N G YRC
Sbjct: 1251 GCDT--QCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCL 1308
Query: 519 CPVGTVRS 542
C G + S
Sbjct: 1309 CYDGFMAS 1316
Score = 122 bits (293), Expect = 1e-27
Identities = 67/178 (37%), Positives = 93/178 (52%), Gaps = 10/178 (5%)
Frame = +3
Query: 27 FRCVCG--PGYR---PAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDEDG 188
F+ +CG PG+ G+ V DEC P C + +C N GS+ C C TG+ ++
Sbjct: 1786 FKTICGNIPGFTFDIHTGKAV-DIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLL 1844
Query: 189 ANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYE-KRGDACVDINECHE-EGVCPS 356
C D+DEC + CQ+ C N+ GSY C C G++ ACVD NEC E VC S
Sbjct: 1845 LVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVC-S 1903
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
G CV+L GS++C+C G++ + C+D DEC + C+N G Y C C G
Sbjct: 1904 HGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPG 1961
Score = 119 bits (286), Expect = 8e-27
Identities = 57/149 (38%), Positives = 76/149 (51%), Gaps = 3/149 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDED 185
VNT GS+RC C G+ G DECA C+ C N G+Y C C G+ D
Sbjct: 1425 VNTPGSYRCACSEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASD 1484
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPSP 359
+C+D+DEC C+N G + C C+DGYE + G C DI+EC + C +
Sbjct: 1485 SRSCQDIDECSFQNICVSGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVN- 1543
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
G CVN G + C CP ++L+ G CVD
Sbjct: 1544 GLCVNTPGRYECNCPPDFQLNPTGVGCVD 1572
Score = 118 bits (283), Expect = 2e-26
Identities = 65/146 (44%), Positives = 79/146 (54%), Gaps = 6/146 (4%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRD--ECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDEDGANC 197
F +C G G V GRD ECA+ P C + +C N GSY C C +GYE D G NC
Sbjct: 751 FHGLCSSG---VGITVDGRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNC 807
Query: 198 RDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCPSPGRC 368
D+DEC + C +C NT GSY C+C GY R + C DINEC E C + G C
Sbjct: 808 IDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINEC-ESNPCVN-GAC 865
Query: 369 VNLLGSFRCVCPRGYRLDAEGARCVD 446
N LGSF C C G +L + G C+D
Sbjct: 866 RNNLGSFNCECSPGSKLSSTGLICID 891
Score = 114 bits (275), Expect = 2e-25
Identities = 72/214 (33%), Positives = 93/214 (43%), Gaps = 34/214 (15%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
N IG+F C+C PG RP G G +EC +P C+ C N GSY C C G++
Sbjct: 2313 NLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSS 2372
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSY------ECSCEDG-----------------Y 293
G C D + Q IC S EC C+ G Y
Sbjct: 2373 SGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQY 2432
Query: 294 EK---RGDACV----DINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRD 452
+K G DI+EC + G+C+N +GSFRC C GY D G C+D D
Sbjct: 2433 KKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLD 2492
Query: 453 ECAQTGR-CQAPCRNYAGGYRCDCPVGTVRSPSG 551
EC+Q+ + C C+N G Y+C CP G V G
Sbjct: 2493 ECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDG 2526
Score = 113 bits (271), Expect = 5e-25
Identities = 68/191 (35%), Positives = 99/191 (51%), Gaps = 10/191 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPG--YRPAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYEL 176
+N IGSFRC C G Y DEC+ C + C N+ GSY C C G++L
Sbjct: 1824 INQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKL 1883
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGV 347
+GA C D +EC + C +C + +GSY+C C +G++ D C+D++EC E
Sbjct: 1884 SPNGA-CVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDEC-ERHP 1941
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGR-CQ-APCRNYAGGYRCD 518
C + G C N +GS+ C+C G+ L C+D DEC+ G+ C+ C N G ++C
Sbjct: 1942 CGN-GTCKNTVGSYNCLCYPGFEL-THNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCL 1999
Query: 519 CPVGTVRSPSG 551
C G +P G
Sbjct: 2000 CNEGYELTPDG 2010
Score = 108 bits (259), Expect = 1e-23
Identities = 54/151 (35%), Positives = 69/151 (45%), Gaps = 3/151 (1%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCE 284
PC + LC +G + DG RD++EC D C IC N GSY C+C
Sbjct: 739 PCQPCPAKNSAEFHGLCSSGVGITVDG---RDINECALDPDICANGICENLRGSYRCNCN 795
Query: 285 DGYEK--RGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC 458
GYE G C+DI+EC + G C N GS+ C CP GY E C D +EC
Sbjct: 796 SGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINEC 855
Query: 459 AQTGRCQAPCRNYAGGYRCDCPVGTVRSPSG 551
CRN G + C+C G+ S +G
Sbjct: 856 ESNPCVNGACRNNLGSFNCECSPGSKLSSTG 886
Score = 95.9 bits (228), Expect = 8e-20
Identities = 67/215 (31%), Positives = 93/215 (43%), Gaps = 41/215 (19%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+N G++RC C G+ PA R + DEC+ + C+N G + C+C GYELD
Sbjct: 1465 LNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVSGTCNNLPGMFHCICDDGYELDR 1524
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVD--INECH----- 335
G NC D+DEC + +C NT G YEC+C ++ G CVD + C+
Sbjct: 1525 TGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGP 1584
Query: 336 ----------EEGVCPSPGRCVNLLG----------------SFRCVCP--RGYRLDAEG 431
E GV S C LG + +CP G+R +
Sbjct: 1585 RGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPIT 1644
Query: 432 ARCVDRDECAQ-TGRCQ-APCRNYAGGYRCDCPVG 530
D DEC + G CQ C N G ++C+CP G
Sbjct: 1645 IILEDIDECQELPGLCQGGNCINTFGSFQCECPQG 1679
Score = 94.7 bits (225), Expect = 2e-19
Identities = 69/209 (33%), Positives = 86/209 (41%), Gaps = 29/209 (13%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRP--AGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
N GS+RC C GY P +GR DEC V CD LC NT GSY C C GY
Sbjct: 785 NLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRT 844
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG--YEKRGDACVD-------IN--- 326
+ C D++ECE + C N GS+ C C G G C+D +N
Sbjct: 845 ETETCEDINECESNP-CVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQD 903
Query: 327 ---ECHEEGVCPSPGRCVNLLGSF-----RC----VCPRGYRLDAEGARCVDRDEC-AQT 467
E + G C L ++ RC CPRG +G C D +EC
Sbjct: 904 SRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGL-ARIKGVTCEDVNECEVFP 962
Query: 468 GRC-QAPCRNYAGGYRCDCPVGTVRSPSG 551
G C C N G + C+CP G +G
Sbjct: 963 GVCPNGRCVNSKGSFHCECPEGLTLDGTG 991
Score = 93.5 bits (222), Expect = 4e-19
Identities = 66/215 (30%), Positives = 97/215 (45%), Gaps = 39/215 (18%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYE 173
R N IGSF+C+C GY P G+ +EC P C C N +GS+ C+C GYE
Sbjct: 1988 RCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYE 2047
Query: 174 LDEDGANCRDVDECERDTHTCQ-QICSNTEGSYECSCEDGY--EKRGDACVDINE--C-- 332
+ + NC D++EC+ D + C C+NT G ++C C G+ G C D + C
Sbjct: 2048 VKSE--NCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFT 2105
Query: 333 -HEEGVCPSPGR---------CVNLLG----------------SFRCVCPRGY-RLDAEG 431
E G C P C + G +F+ +CP G+ + +
Sbjct: 2106 NFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLH 2165
Query: 432 ARCVDRDECAQT-GRC-QAPCRNYAGGYRCDCPVG 530
D +EC ++ G C C N G +RC+CP+G
Sbjct: 2166 DTREDVNECLESPGICSNGQCINTDGSFRCECPMG 2200
Score = 91.9 bits (218), Expect = 1e-18
Identities = 69/219 (31%), Positives = 93/219 (42%), Gaps = 36/219 (16%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
R VN+ GSF+C+C G+ G+ DEC + +C N DGS+ C+C+ G+ L
Sbjct: 589 RCVNSDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVL 648
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDI---NECH-- 335
+G C DVDEC+ C N+EGS+ C C G G CVD + C+
Sbjct: 649 APNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGG 708
Query: 336 -EEGVC--PSPGR-------CVN---------------LLGSFRCVCPRGYRLDAEGARC 440
++GVC P PG C N F +C G + +G
Sbjct: 709 IKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGR-- 766
Query: 441 VDRDECA-QTGRC-QAPCRNYAGGYRCDCPVGTVRSPSG 551
D +ECA C C N G YRC+C G SG
Sbjct: 767 -DINECALDPDICANGICENLRGSYRCNCNSGYEPDASG 804
Score = 89.8 bits (213), Expect = 5e-18
Identities = 58/183 (31%), Positives = 79/183 (43%), Gaps = 5/183 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
NT G F+C+C PG+ + G R D C + C + +
Sbjct: 2073 NTPGGFQCLCPPGFVLSDNGRRCFDTR-------QSFCFTNFENGKCSVPKAFNTTKAKC 2125
Query: 192 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGY---EKRGDACVDINECHEE-GVCPSP 359
C + E C+ + E +++ C G+ D D+NEC E G+C S
Sbjct: 2126 CCSKMPG-EGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGIC-SN 2183
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPVGTV 536
G+C+N GSFRC CP GY LD G RCVD DEC+ C C N G + C+C G
Sbjct: 2184 GQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFECNCNEGFE 2243
Query: 537 RSP 545
P
Sbjct: 2244 PGP 2246
Score = 89.4 bits (212), Expect = 7e-18
Identities = 46/111 (41%), Positives = 64/111 (57%), Gaps = 4/111 (3%)
Frame = +3
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDIN 326
CR G+ + C+DVDEC+ CQ C NT GS+EC C G+++ C DI+
Sbjct: 260 CRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDID 319
Query: 327 ECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC 476
EC G+C + G C N +GS+ CVCPRGY +G+RC+D+ +TG C
Sbjct: 320 ECSIIPGICET-GECSNTVGSYFCVCPRGYVTSTDGSRCIDQ----RTGMC 365
Score = 85.4 bits (202), Expect = 1e-16
Identities = 52/148 (35%), Positives = 63/148 (42%), Gaps = 4/148 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT GSF C C G+ G+ D EC C C N G Y C C GY
Sbjct: 2589 NTPGSFSCECQRGFSLDATGLNCEDVDECDGNHR-CQHGCQNILGGYRCGCPQGYIQHYQ 2647
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCPSP 359
C D +EC C NT GSY+C+C G +++ AC D+NEC P
Sbjct: 2648 WNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNEC-SSSKNPCN 2706
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCV 443
C N G + C CP GY +G CV
Sbjct: 2707 YGCSNTEGGYLCGCPPGYYRVGQG-HCV 2733
Score = 83.4 bits (197), Expect = 5e-16
Identities = 59/185 (31%), Positives = 78/185 (42%), Gaps = 11/185 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD 179
+NT GSF+C C GY + R DEC P C C+NT G+Y C+C Y
Sbjct: 1666 INTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQV 1725
Query: 180 EDGANCRDVDE--CERDTH--TCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGV 347
G NC D+ + C R + TC+ C C K G+ C
Sbjct: 1726 NGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAGN-----KPCEP--- 1777
Query: 348 CPSPGRCVNLLGSFRCVCPR--GYRLDAEGARCVDRDECAQ-TGRC-QAPCRNYAGGYRC 515
CP+PG F+ +C G+ D + VD DEC + G C C N G +RC
Sbjct: 1778 CPTPG-----TADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRC 1832
Query: 516 DCPVG 530
+CP G
Sbjct: 1833 ECPTG 1837
Score = 82.6 bits (195), Expect = 8e-16
Identities = 60/181 (33%), Positives = 78/181 (43%), Gaps = 9/181 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRG-VRGR-DECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
VNT G + C C P ++ P G G V R C ++ P DGS C G +
Sbjct: 1547 VNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGP------RGDGSLSCNTEIGVGV 1600
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV--DINECHE-EGV 347
C TC + ++TE C +G+ + DI+EC E G+
Sbjct: 1601 SRSSCCCSLGKAWGNPCETCPPV-NSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGL 1659
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC-QAPCRNYAGGYRCDC 521
C G C+N GSF+C CP+GY L + C D DEC A G C C N G Y C C
Sbjct: 1660 CQG-GNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCIC 1718
Query: 522 P 524
P
Sbjct: 1719 P 1719
Score = 82.2 bits (194), Expect = 1e-15
Identities = 59/172 (34%), Positives = 76/172 (44%), Gaps = 27/172 (15%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT GS+ C C PGY R +EC P + C N GS++C C G +L
Sbjct: 827 NTPGSYSCTCPPGYVFRTETETCEDINECESNPC-VNGACRNNLGSFNCECSPGSKLSST 885
Query: 186 GANCRDV-----------DECERDTH--TCQQICSNTEGS----------YECSCEDGYE 296
G C D CE + + T + C T G+ + +C G
Sbjct: 886 GLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLA 945
Query: 297 K-RGDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
+ +G C D+NEC GVCP+ GRCVN GSF C CP G LD G C+D
Sbjct: 946 RIKGVTCEDVNECEVFPGVCPN-GRCVNSKGSFHCECPEGLTLDGTGRVCLD 996
Score = 79.0 bits (186), Expect = 1e-14
Identities = 46/124 (37%), Positives = 63/124 (50%), Gaps = 7/124 (5%)
Frame = +3
Query: 198 RDVDECERDTHTCQQ-ICSNTEGSYECSCEDGY--EKRGDACVDINECH-EEGVCPSPGR 365
+D++EC+ C C NT GS++C C G+ + C DI+EC +C S G
Sbjct: 1071 KDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGS-GI 1129
Query: 366 CVNLLGSFRCVCPRGYRLDAEGAR-CVDRDECAQTGR-CQA-PCRNYAGGYRCDCPVGTV 536
CVN GSF C C GY + C+D D C + C+ C N G ++CDCP+G
Sbjct: 1130 CVNTPGSFECECFEGYESGFMMMKNCMDIDGCERNPLLCRGGTCVNTEGSFQCDCPLGHE 1189
Query: 537 RSPS 548
SPS
Sbjct: 1190 LSPS 1193
Score = 78.2 bits (184), Expect = 2e-14
Identities = 59/192 (30%), Positives = 85/192 (44%), Gaps = 12/192 (6%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDC-------LCRTGY 170
NT+G++ C+C P Y G D +R C + + T + +C Y
Sbjct: 1709 NTLGNYTCICPPEYMQVNGGHNCMD---MRKSFCYRSYNGTTCENELPFNVTKRMCCCTY 1765
Query: 171 ELDEDGANCRDVDECERD-THTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHE-EG 344
+ + G + + C T + IC N G ++ VDI+EC E G
Sbjct: 1766 NVGKAGN--KPCEPCPTPGTADFKTICGNIPGFT-------FDIHTGKAVDIDECKEIPG 1816
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQ--APCRNYAGGYRC 515
+C + G C+N +GSFRC CP G+ + C D DEC+ CQ A C N G YRC
Sbjct: 1817 ICAN-GVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRC 1875
Query: 516 DCPVGTVRSPSG 551
+C G SP+G
Sbjct: 1876 ECAAGFKLSPNG 1887
Score = 78.2 bits (184), Expect = 2e-14
Identities = 47/149 (31%), Positives = 65/149 (43%), Gaps = 13/149 (8%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCD---QLCHNTDGSYDCLCRTG 167
R +NT GS+ C C GY R + + DECA C+ +C N G++ C+C G
Sbjct: 2266 RCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPG 2325
Query: 168 YELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYE--KRGDACVDINE--C 332
DG C D +EC C+ C N GSY C C +G++ G C+D + C
Sbjct: 2326 MARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLC 2385
Query: 333 HEE---GVCPSPGRCVNLLGSFRCVCPRG 410
E +C NL+ C C G
Sbjct: 2386 FAEVLQTICQMASSSRNLVTKSECCCDGG 2414
Score = 74.5 bits (175), Expect = 2e-13
Identities = 43/119 (36%), Positives = 55/119 (46%), Gaps = 6/119 (5%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCR--TGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECS 278
PC+ Y LC G+ + D+DEC+ CQ C NT GS++C
Sbjct: 1616 PCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCE 1675
Query: 279 CEDGYEKRGDA--CVDINECHEE-GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
C GY D C DI+EC GVC PG C N LG++ C+CP Y G C+D
Sbjct: 1676 CPQGYYLSEDTRICEDIDECFAHPGVC-GPGTCYNTLGNYTCICPPEYMQVNGGHNCMD 1733
Score = 72.9 bits (171), Expect = 7e-13
Identities = 36/87 (41%), Positives = 46/87 (52%), Gaps = 3/87 (3%)
Frame = +3
Query: 300 RGDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGR 473
R AC D++EC G+C G C+N +GSF C CP G++ +C D DEC+ G
Sbjct: 269 RTGACQDVDECQAIPGICQG-GNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGI 327
Query: 474 CQ-APCRNYAGGYRCDCPVGTVRSPSG 551
C+ C N G Y C CP G V S G
Sbjct: 328 CETGECSNTVGSYFCVCPRGYVTSTDG 354
Score = 69.3 bits (162), Expect = 8e-12
Identities = 57/187 (30%), Positives = 76/187 (40%), Gaps = 41/187 (21%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDV--DEC--ERDTHTC---- 236
+EC V P C C N+ GS+ C C G LD G C D+ ++C + D C
Sbjct: 956 NECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPV 1015
Query: 237 ------QQICSNTEGSYECSCED-----------------GYEKRGDACV------DINE 329
C ++ CE+ G+ RGD DINE
Sbjct: 1016 PGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINE 1075
Query: 330 CHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC-QAPCRNYA 500
C G+C + G+C N +GSF+C C G+ LD E C D DEC C C N
Sbjct: 1076 CKAFPGMC-TYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTP 1134
Query: 501 GGYRCDC 521
G + C+C
Sbjct: 1135 GSFECEC 1141
Score = 68.1 bits (159), Expect = 2e-11
Identities = 44/120 (36%), Positives = 53/120 (44%), Gaps = 11/120 (9%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNT 257
DEC P C C NT GS++C C G++ E C D+DEC C+ CSNT
Sbjct: 277 DECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNT 336
Query: 258 EGSYECSCEDGY--EKRGDACVDINECHEEGVCPS---PGRCVNLL----GSFRCVCPRG 410
GSY C C GY G C+D G+C S GRC L +C C G
Sbjct: 337 VGSYFCVCPRGYVTSTDGSRCID----QRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPG 392
Score = 62.5 bits (145), Expect = 1e-09
Identities = 28/72 (38%), Positives = 37/72 (51%)
Frame = +3
Query: 333 HEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYR 512
H +C + GRC+ + S+RC C GY+ DA G C+D DEC C N G Y
Sbjct: 499 HHANLCLN-GRCIPTVSSYRCECNMGYKQDANG-DCIDVDECTSNPCTNGDCVNTPGSYY 556
Query: 513 CDCPVGTVRSPS 548
C C G R+P+
Sbjct: 557 CKCHAGFQRTPT 568
Score = 58.8 bits (136), Expect = 1e-08
Identities = 34/101 (33%), Positives = 46/101 (45%), Gaps = 7/101 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD 179
+NT+GSF C C G++ + + DEC++ P C+ C NT GSY C+C GY
Sbjct: 292 INTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTS 351
Query: 180 EDGANCRD--VDECERD--THTCQQICSNTEGSYECSCEDG 290
DG+ C D C C Q +C CE G
Sbjct: 352 TDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPG 392
Score = 48.0 bits (109), Expect = 2e-05
Identities = 60/236 (25%), Positives = 89/236 (37%), Gaps = 63/236 (26%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGV------RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGY- 170
N +GSF C C PG + + G+ +G ++ C+ + +C G
Sbjct: 867 NNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAA 926
Query: 171 --------ELDE---------DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDG-- 290
ELD G C DV+ECE C C N++GS+ C C +G
Sbjct: 927 WGSPCERCELDTACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLT 986
Query: 291 YEKRGDACVDI--NECH-----EEGVCPSPGR-----CVNLLGS---------------- 386
+ G C+DI +C+ +E + P PG+ C +G+
Sbjct: 987 LDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKE 1046
Query: 387 FRCVCPRGYRLDAEGARCVDR------DEC-AQTGRC-QAPCRNYAGGYRCDCPVG 530
+ +CPRG G R +EC A G C CRN G ++C C G
Sbjct: 1047 YETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSG 1102
>X63556-1|CAA45118.1| 3002|Homo sapiens fibrillin protein.
Length = 3002
Score = 192 bits (467), Expect = 9e-49
Identities = 82/177 (46%), Positives = 102/177 (57%), Gaps = 3/177 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRP--AGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN GS+ C+C GY P G +EC P PC+ +C NT+GSY C C GY L E
Sbjct: 2550 VNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQE 2609
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEE-GVCPSP 359
DG +C+D+DEC H CQ +C NT G + C C G+ + +C+D NEC + +C S
Sbjct: 2610 DGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSK 2669
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
G C N GSF C C RG+ LD G+ C D DEC RCQ C+N GGYRC CP G
Sbjct: 2670 GICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQHGCQNIIGGYRCSCPQG 2726
Score = 157 bits (380), Expect = 3e-38
Identities = 79/187 (42%), Positives = 101/187 (54%), Gaps = 9/187 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD- 179
NTIGSF+C C G+ R DEC + P C + C NT G ++C C GYE
Sbjct: 1177 NTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGF 1236
Query: 180 EDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEG-V 347
NC D+DEC+RD C+ +C NTEGSY C C G++ + AC+DINEC +
Sbjct: 1237 MMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHL 1296
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRCDCP 524
CP+ GRCVNL+G ++C C GY + CVD DEC+ G C+ C N G Y C C
Sbjct: 1297 CPN-GRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQ 1355
Query: 525 VGTVRSP 545
G P
Sbjct: 1356 PGFALMP 1362
Score = 156 bits (378), Expect = 6e-38
Identities = 75/186 (40%), Positives = 96/186 (51%), Gaps = 5/186 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDE 182
VNTIG F C C PG+ +EC C +C NT GS+ C C+ G+ LD+
Sbjct: 2632 VNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQ 2691
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK--RGDACVDINECHEEGVCPS 356
G++C DVDECE + H CQ C N G Y CSC GY + + + CVD NEC +C
Sbjct: 2692 TGSSCEDVDECEGN-HRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGG 2750
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQT-GRCQAPCRNYAGGYRCDCPVGT 533
C N LGS++C+CP G++ + C D +EC C C N GGY C CP G
Sbjct: 2751 AS-CHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGCSNTEGGYLCGCPPGY 2809
Query: 534 VRSPSG 551
R G
Sbjct: 2810 FRIGQG 2815
Score = 152 bits (368), Expect = 9e-37
Identities = 75/180 (41%), Positives = 100/180 (55%), Gaps = 6/180 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRG-VRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
+NT GS+RC C PGYR G R+EC P C C +T GS+ CLC TG++ ++
Sbjct: 1956 INTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTND 2015
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY-EKRGDACVDINECHE-EGVCPS 356
D C D++ECERD C NT GS+ C C G+ + C+D++EC G
Sbjct: 2016 DQTMCLDINECERDA-CGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCR 2074
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRCDCPVG 530
G+C+N +GSF+C C GY + +G CVD +EC R AP C+N G YRC CP G
Sbjct: 2075 NGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPG 2134
Score = 147 bits (355), Expect = 3e-35
Identities = 76/177 (42%), Positives = 88/177 (49%), Gaps = 6/177 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELDED 185
NT GSF+C C PG+ G DEC+ C Q C NT GSY CLC+ GY D
Sbjct: 1472 NTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYT--GD 1529
Query: 186 GANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPS 356
G C D+DEC + + C C N G Y C C+ G+ D AC DI+EC +C
Sbjct: 1530 GFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVF 1589
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCP 524
G C NL G FRC C GY LD G C D +EC C C N G Y CDCP
Sbjct: 1590 -GTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYICDCP 1645
Score = 143 bits (346), Expect = 4e-34
Identities = 73/187 (39%), Positives = 94/187 (50%), Gaps = 7/187 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELD 179
NT GSF C C GY + G +EC + C + +C NT GS+ C C G+
Sbjct: 1429 NTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWI-- 1486
Query: 180 EDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCP 353
DG C D+DEC TH C Q C NT GSY C C++GY G C D++EC E
Sbjct: 1487 GDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLC 1546
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ-APCRNYAGGYRCDCPVG 530
G+C+N G +RC C G+ A+G C D DEC+ C C N G +RC+C +G
Sbjct: 1547 GNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIG 1606
Query: 531 TVRSPSG 551
SG
Sbjct: 1607 YELDRSG 1613
Score = 141 bits (341), Expect = 2e-33
Identities = 68/180 (37%), Positives = 96/180 (53%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT GS++C C GY + GR + DECA + C LC NT G + C C G+ +
Sbjct: 2592 NTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFT--QH 2649
Query: 186 GANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGY--EKRGDACVDINECHEEGVCP 353
+C D +EC D + C + IC NT GS+ C C+ G+ ++ G +C D++EC C
Sbjct: 2650 HTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQ 2709
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPVG 530
C N++G +RC CP+GY + +CVD +EC C A C N G Y+C CP G
Sbjct: 2710 HG--CQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAG 2767
Score = 139 bits (337), Expect = 5e-33
Identities = 72/187 (38%), Positives = 94/187 (50%), Gaps = 9/187 (4%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
R VN IG ++C C PGY P DEC++ C+ C N++GSY+C C+ G+ L
Sbjct: 1301 RCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFAL 1360
Query: 177 DEDGANCRDVDECERDTHTCQ-QICSNTEGSYECSCEDGYEKRGD--ACVDINECH-EEG 344
D +C D+DECE + + C C+N G Y C C DG+ D CVD+NEC
Sbjct: 1361 MPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPN 1420
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC---AQTGRCQAPCRNYAGGYRC 515
+C S G C N GSF C C GY C D +EC A A C N AG ++C
Sbjct: 1421 ICLS-GTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKC 1479
Query: 516 DCPVGTV 536
C G +
Sbjct: 1480 SCSPGWI 1486
Score = 139 bits (336), Expect = 7e-33
Identities = 69/188 (36%), Positives = 97/188 (51%), Gaps = 8/188 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDE 182
N G +RC+C G+ + + +EC + P C C NT GS+ C C GY +
Sbjct: 1387 NIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKK 1446
Query: 183 DGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGDACVDINEC-HEEGVCP 353
C D++ECE H C +C+NT GS++CSC G+ G C D++EC + +C
Sbjct: 1447 GKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCS 1506
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQT-GRC-QAPCRNYAGGYRCDCPV 527
C N +GS+RC+C GY +G C D DEC++ C C N GGYRC+C +
Sbjct: 1507 QHADCKNTMGSYRCLCKEGY--TGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDM 1564
Query: 528 GTVRSPSG 551
G V S G
Sbjct: 1565 GFVPSADG 1572
Score = 138 bits (334), Expect = 1e-32
Identities = 71/186 (38%), Positives = 94/186 (50%), Gaps = 6/186 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+NT GS+RC C GY AG DEC+V P + C N G ++C C G+E
Sbjct: 2274 INTDGSYRCECPFGYTLAGNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFE-PGPM 2332
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHE--EGVCPS 356
C D++EC ++ C C NT GSYEC C GY R D C D +EC E
Sbjct: 2333 MTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEK 2392
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQ-APCRNYAGGYRCDCPVG 530
C NL+G++ C+C GY+ +G CVD +EC + G C+ C N G Y C+C G
Sbjct: 2393 QMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDG 2452
Query: 531 TVRSPS 548
SP+
Sbjct: 2453 FTASPN 2458
Score = 137 bits (332), Expect = 2e-32
Identities = 69/178 (38%), Positives = 95/178 (53%), Gaps = 5/178 (2%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRG-VRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELD 179
R + T GS+RC C G++ RG DEC P + C N GSY C CR GY+
Sbjct: 595 RCIPTPGSYRCECNKGFQLDLRGECIDVDECEKNPCAGGE-CINNQGSYTCQCRAGYQST 653
Query: 180 EDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVC 350
CRD+DEC ++ C C NT+GS+ C C G+ + G C D++EC +C
Sbjct: 654 LTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMC 713
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDC 521
+ G C+N GSF+C+C G++L ++G C D +EC G C C N G YRC+C
Sbjct: 714 LN-GMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCEC 770
Score = 136 bits (328), Expect = 6e-32
Identities = 75/188 (39%), Positives = 98/188 (52%), Gaps = 7/188 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDED 185
++T+GSF C+C G++ D C C NT GS++C C G+ L +
Sbjct: 1997 IDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHN 2056
Query: 186 GANCRDVDECERDT-HTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCP 353
+C DVDEC + C+ C NT GS++C C +GYE D CVDINEC E
Sbjct: 2057 N-DCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKC 2115
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQA--PCRNYAGGYRCDCPV 527
+PG C NL GS+RC+CP GY L E +C D DEC + A C N G ++C CP
Sbjct: 2116 APGTCQNLDGSYRCICPPGYSLQNE--KCEDIDECVEEPEICALGTCSNTEGSFKCLCPE 2173
Query: 528 GTVRSPSG 551
G S SG
Sbjct: 2174 GFSLSSSG 2181
Score = 130 bits (313), Expect = 4e-30
Identities = 65/180 (36%), Positives = 88/180 (48%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
NT GS+RC C PG++ P +EC + C C N G Y C C GY
Sbjct: 1262 NTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTP 1321
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPS 356
D C D+DEC C+ C+N+EGSYECSC+ G+ D +C DI+EC +
Sbjct: 1322 DRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICD 1381
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC-QAPCRNYAGGYRCDCPVG 530
G+C N+ G +RC+C G+ + CVD +EC C C N G + C C +G
Sbjct: 1382 GGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMG 1441
Score = 130 bits (313), Expect = 4e-30
Identities = 65/155 (41%), Positives = 80/155 (51%), Gaps = 7/155 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGV-RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
N IG F C C G+ P +ECA P C C NT GSY+C C GY L ED
Sbjct: 2314 NVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDR 2373
Query: 189 ANCRDVDECERDTHTC---QQICSNTEGSYECSCEDGYEKR--GDACVDINECH-EEGVC 350
C+D DECE H C Q C N G+Y C C GY++R G+ CVD NEC + G+C
Sbjct: 2374 RMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGIC 2433
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE 455
+ GRC+N GS+ C C G+ C+D E
Sbjct: 2434 EN-GRCLNTRGSYTCECNDGFTASPNQDECLDNRE 2467
Score = 127 bits (307), Expect = 2e-29
Identities = 67/182 (36%), Positives = 90/182 (49%), Gaps = 11/182 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD 179
+N GS+ C C GY+ RD EC C+ C NTDGS+ C+C G+ +
Sbjct: 636 INNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVT 695
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCP 353
DG NC D+DEC +C N +GS++C C+ G++ D C DINEC G+C
Sbjct: 696 RDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICM 755
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVD---RDEC---AQTGRCQAPCRNYAGGYRC 515
+ GRCVN GS+RC C G + +G CVD R C + G+C P C
Sbjct: 756 N-GRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSEC 814
Query: 516 DC 521
C
Sbjct: 815 CC 816
Score = 126 bits (304), Expect = 5e-29
Identities = 72/188 (38%), Positives = 89/188 (47%), Gaps = 10/188 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA---GRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYEL 176
VNT G F C C GY + DEC P C +CHNT+GSY C C G++L
Sbjct: 1218 VNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQL 1277
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECH-EEG 344
+ + C D++ECE H C C N G Y+C+C GY D CVDI+EC G
Sbjct: 1278 SPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNG 1337
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQ-APCRNYAGGYRCD 518
C + C N GS+ C C G+ L + C D DEC C C N G YRC
Sbjct: 1338 GCET--FCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCL 1395
Query: 519 CPVGTVRS 542
C G + S
Sbjct: 1396 CYDGFMAS 1403
Score = 126 bits (304), Expect = 5e-29
Identities = 68/179 (37%), Positives = 88/179 (49%), Gaps = 9/179 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA-GRGVRGRDECAV-RPPPC-DQLCHNTDGSYDCLCRTGYELDE 182
NTIGSF C C G+ + DECA C + C NT GS+ C C GYE+
Sbjct: 2038 NTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAP 2097
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSP 359
DG C D++EC + C C N +GSY C C GY + + C DI+EC EE +
Sbjct: 2098 DGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEICAL 2157
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVD--RDEC---AQTGRCQAPCRNYAGGYRCDC 521
G C N GSF+C+CP G+ L + G RC D C + G+C +P C C
Sbjct: 2158 GTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCC 2216
Score = 122 bits (294), Expect = 8e-28
Identities = 65/173 (37%), Positives = 91/173 (52%), Gaps = 7/173 (4%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C G G+ G + DEC V C + C N GSY C+C+TGY D G +C D++
Sbjct: 2521 CPHGRGFMTNGADI---DECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLN 2577
Query: 210 ECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINEC-HEEGVCPSPGRCVNLL 380
EC + C IC NTEGSY+CSC GY ++ G +C D++EC ++ C CVN +
Sbjct: 2578 ECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQF--LCVNTI 2635
Query: 381 GSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC--QAPCRNYAGGYRCDCPVG 530
G F C CP G+ C+D +EC + C + C+N G + C+C G
Sbjct: 2636 GGFTCKCPPGF--TQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRG 2686
Score = 122 bits (293), Expect = 1e-27
Identities = 60/161 (37%), Positives = 84/161 (52%), Gaps = 7/161 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNT 257
+EC + P C C NT GS+ C C +G+ LD + NC D+DEC C + C NT
Sbjct: 1161 NECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNT 1220
Query: 258 EGSYECSCEDGYEK---RGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAE 428
G +EC C++GYE C+DI+EC + + G C N GS+RC CP G++L
Sbjct: 1221 PGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPN 1280
Query: 429 GARCVDRDECAQTGR-C-QAPCRNYAGGYRCDCPVGTVRSP 545
+ C+D +EC + C C N G Y+C C G +P
Sbjct: 1281 ISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTP 1321
Score = 117 bits (282), Expect = 2e-26
Identities = 72/191 (37%), Positives = 93/191 (48%), Gaps = 10/191 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPG--YRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYEL 176
+N +GSFRC C G Y DEC P C + C NT GSY C C+ GY
Sbjct: 1914 INMVGSFRCECPVGFFYNDKLLVCEDIDECQ-NGPVCQRNAECINTAGSYRCDCKPGYRF 1972
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGV 347
G C D +EC+ + C C +T GS+ C C G++ D C+DINEC E
Sbjct: 1973 TSTG-QCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINEC-ERDA 2030
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGR-CQ-APCRNYAGGYRCD 518
C + G C N +GSF C C G+ L + C+D DECA G C+ C N G ++C
Sbjct: 2031 CGN-GTCRNTIGSFNCRCNHGFIL-SHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQ 2088
Query: 519 CPVGTVRSPSG 551
C G +P G
Sbjct: 2089 CNEGYEVAPDG 2099
Score = 117 bits (281), Expect = 3e-26
Identities = 57/139 (41%), Positives = 74/139 (53%), Gaps = 3/139 (2%)
Frame = +3
Query: 123 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 302
C T GSY C C G++LD G C DVDECE++ + C N +GSY C C GY+
Sbjct: 596 CIPTPGSYRCECNKGFQLDLRG-ECIDVDECEKNPCAGGE-CINNQGSYTCQCRAGYQST 653
Query: 303 --GDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC 476
C DI+EC + G + GRC+N GSF CVC G+ + +G C D DEC+ C
Sbjct: 654 LTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMC 713
Query: 477 -QAPCRNYAGGYRCDCPVG 530
C N G ++C C G
Sbjct: 714 LNGMCINEDGSFKCICKPG 732
Score = 117 bits (281), Expect = 3e-26
Identities = 67/162 (41%), Positives = 78/162 (48%), Gaps = 6/162 (3%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTE 260
DEC P C C NTDGSY C C GY L G C D DEC C N
Sbjct: 2260 DECK-EPDVCKHGQCINTDGSYRCECPFGYTLA--GNECVDTDECSVGNPCGNGTCKNVI 2316
Query: 261 GSYECSCEDGYEKRGD-ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGAR 437
G +EC+CE+G+E C DINEC + + + RCVN GS+ C CP GY L +
Sbjct: 2317 GGFECTCEEGFEPGPMMTCEDINECAQNPLLCA-FRCVNTYGSYECKCPVGYVLREDRRM 2375
Query: 438 CVDRDECAQTGR-C---QAPCRNYAGGYRCDCPVGTVRSPSG 551
C D DEC + C Q C+N G Y C C G R P G
Sbjct: 2376 CKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDG 2417
Score = 116 bits (279), Expect = 6e-26
Identities = 61/163 (37%), Positives = 76/163 (46%), Gaps = 3/163 (1%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDG 188
NT+GS+RC+C GY G DEC+ C C N G Y C C G+ DG
Sbjct: 1513 NTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADG 1572
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPSPG 362
C D+DEC C N G + C CE GYE + G C D+NEC + C S G
Sbjct: 1573 KACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCIS-G 1631
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCR 491
CVN GS+ C CP + L+ CVD ++G C R
Sbjct: 1632 NCVNTPGSYICDCPPDFELNPTRVGCVD----TRSGNCYLDIR 1670
Score = 113 bits (273), Expect = 3e-25
Identities = 57/158 (36%), Positives = 82/158 (51%), Gaps = 5/158 (3%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQI--CSN 254
DEC P C+ +C N GS+ C C G+ ++ C D+DEC+ CQ+ C N
Sbjct: 1899 DECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGP-VCQRNAECIN 1957
Query: 255 TEGSYECSCEDGYEKRGDA-CVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAE 428
T GSY C C+ GY C D NEC E +C S G+C++ +GSF C+C G++ + +
Sbjct: 1958 TAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNIC-SHGQCIDTVGSFYCLCHTGFKTNDD 2016
Query: 429 GARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVRS 542
C+D +EC + CRN G + C C G + S
Sbjct: 2017 QTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILS 2054
Score = 112 bits (270), Expect = 7e-25
Identities = 72/215 (33%), Positives = 93/215 (43%), Gaps = 35/215 (16%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
N IG++ C+CGPGY RP G G +EC +P C+ C NT GSY C C G+
Sbjct: 2398 NLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASP 2457
Query: 183 DGANCRDVDECERDTHTCQQICS------NTEGSYECSCED--GYEKRGDAC-------- 314
+ C D E T Q +C N EC C+ G+ + C
Sbjct: 2458 NQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAF 2517
Query: 315 --------------VDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR 449
DI+EC VC + G CVN GS+ C+C GY D G CVD
Sbjct: 2518 KKLCPHGRGFMTNGADIDECKVIHDVCRN-GECVNDRGSYHCICKTGYTPDITGTSCVDL 2576
Query: 450 DECAQTGR-CQAPCRNYAGGYRCDCPVGTVRSPSG 551
+EC Q + C C+N G Y+C CP G + G
Sbjct: 2577 NECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDG 2611
Score = 109 bits (261), Expect = 8e-24
Identities = 61/158 (38%), Positives = 83/158 (52%), Gaps = 9/158 (5%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C GPG AG + +ECA+ P C +C N G+Y C+C +GYE+D G NC D++
Sbjct: 842 CSSGPGMTSAGSDI---NECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDIN 898
Query: 210 ECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLL 380
EC ++ C C NT GS+ C+C G+ + D C DI+EC E C + G C N
Sbjct: 899 ECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDEC-ESSPCIN-GVCKNSP 956
Query: 381 GSFRCVCPRGYRLDAEGARCVD--RDECAQT---GRCQ 479
GSF C C LD C++ + C QT GRC+
Sbjct: 957 GSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCE 994
Score = 103 bits (248), Expect = 3e-22
Identities = 51/150 (34%), Positives = 69/150 (46%), Gaps = 3/150 (2%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCE 284
PC Y LC +G + G+ D++EC D C IC N G+Y+C C
Sbjct: 826 PCQPCPAQNSAEYQALCSSGPGMTSAGS---DINECALDPDICPNGICENLRGTYKCICN 882
Query: 285 DGYE--KRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC 458
GYE G CVDINEC + G+C N GSF C CP+G+ + C D DEC
Sbjct: 883 SGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDEC 942
Query: 459 AQTGRCQAPCRNYAGGYRCDCPVGTVRSPS 548
+ C+N G + C+C + P+
Sbjct: 943 ESSPCINGVCKNSPGSFICECSSESTLDPT 972
Score = 96.7 bits (230), Expect = 5e-20
Identities = 44/110 (40%), Positives = 60/110 (54%), Gaps = 4/110 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
R +NT GSF CVC G+ G+ DEC++R + +C N DGS+ C+C+ G++L
Sbjct: 676 RCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQL 735
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVD 320
DG C+D++ECE C NT+GSY C C G G CVD
Sbjct: 736 ASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVD 785
Score = 95.5 bits (227), Expect = 1e-19
Identities = 53/147 (36%), Positives = 69/147 (46%), Gaps = 4/147 (2%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCRTGYEL---DEDGANCRDVDECERDTHTCQQICSNTEGSYECS 278
PC+ D ++ +C G + +D A D+DEC+ C NT+GSY C
Sbjct: 2226 PCELCPTEPDEAFRQICPYGSGIIVGPDDSAV--DMDECKEPDVCKHGQCINTDGSYRCE 2283
Query: 279 CEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC 458
C GY G+ CVD +EC C + G C N++G F C C G+ C D +EC
Sbjct: 2284 CPFGYTLAGNECVDTDECSVGNPCGN-GTCKNVIGGFECTCEEGFE-PGPMMTCEDINEC 2341
Query: 459 AQTG-RCQAPCRNYAGGYRCDCPVGTV 536
AQ C C N G Y C CPVG V
Sbjct: 2342 AQNPLLCAFRCVNTYGSYECKCPVGYV 2368
Score = 89.0 bits (211), Expect = 1e-17
Identities = 68/216 (31%), Positives = 89/216 (41%), Gaps = 42/216 (19%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+N G +RC C G+ P+ G+ DEC++ CHN G + C C GYELD
Sbjct: 1552 LNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDR 1611
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE-----------KRGDACVDI-- 323
G NC DV+EC T C NT GSY C C +E + G+ +DI
Sbjct: 1612 SGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRP 1671
Query: 324 ------NECHEE-GVCPSPGRCVNLLG----------------SFRCVCP--RGYRLDAE 428
C E GV S C LG ++ +CP G+R +
Sbjct: 1672 RGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPI 1731
Query: 429 GARCVDRDECAQ-TGRCQ-APCRNYAGGYRCDCPVG 530
D DEC + G CQ C N G ++C CP G
Sbjct: 1732 TVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTG 1767
Score = 87.4 bits (207), Expect = 3e-17
Identities = 57/179 (31%), Positives = 79/179 (44%), Gaps = 7/179 (3%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVR-PPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C C G A G +EC +R P ++LC G E+ +D++
Sbjct: 1111 CCCSVG---AAWGTEECEECPMRNTPEYEELCPRGPGF------ATKEITNGKPFFKDIN 1161
Query: 210 ECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLL 380
EC+ C C NT GS++C C+ G+ + C DI+EC G+CVN
Sbjct: 1162 ECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTP 1221
Query: 381 GSFRCVCPRGYRLDAEGAR-CVDRDECAQTGR-CQAP-CRNYAGGYRCDCPVGTVRSPS 548
G F C C GY + C+D DEC + C+ C N G YRC+CP G SP+
Sbjct: 1222 GDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPN 1280
Score = 85.0 bits (201), Expect = 2e-16
Identities = 61/209 (29%), Positives = 91/209 (43%), Gaps = 29/209 (13%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
N G+++C+C GY G+ +EC + CD C NT GS+ C C G+
Sbjct: 872 NLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKP 931
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSY--ECSCEDGYEKRGDACVDI--NECHE---E 341
D C D+DECE + +C N+ GS+ ECS E + C++ C + +
Sbjct: 932 DLKTCEDIDECE-SSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVID 990
Query: 342 GVC-------PSPGRCVNLLGS---FRC-------VCPRGYRLDAEGARCVDRDEC-AQT 467
G C +C + LG+ C +C +GY +G +C D DEC
Sbjct: 991 GRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYS-RIKGTQCEDIDECEVFP 1049
Query: 468 GRCQ-APCRNYAGGYRCDCPVGTVRSPSG 551
G C+ C N G ++C CP G +G
Sbjct: 1050 GVCKNGLCVNTRGSFKCQCPSGMTLDATG 1078
Score = 84.6 bits (200), Expect = 2e-16
Identities = 52/149 (34%), Positives = 65/149 (43%), Gaps = 13/149 (8%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQL---CHNTDGSYDCLCRTG 167
R VNT GS+ C C GY R R + DEC C + C N G+Y C+C G
Sbjct: 2351 RCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPG 2410
Query: 168 YELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGY--EKRGDACVDINE--C 332
Y+ DG C D +EC+ C+ C NT GSY C C DG+ D C+D E C
Sbjct: 2411 YQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYC 2470
Query: 333 HEE---GVCPSPGRCVNLLGSFRCVCPRG 410
E +C N + C C G
Sbjct: 2471 FTEVLQNMCQIGSSNRNPVTKSECCCDGG 2499
Score = 83.4 bits (197), Expect = 5e-16
Identities = 49/139 (35%), Positives = 64/139 (46%), Gaps = 9/139 (6%)
Frame = +3
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKR--GDACVDIN 326
CR G+ + C+DVDEC+ CQ C NT GS+EC C G++ C DI+
Sbjct: 362 CRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDID 421
Query: 327 ECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD-RDECAQT----GRCQAPC 488
EC G+C G C N + S+ C CP G+ +G RC+D R T GRC
Sbjct: 422 ECSTIPGICEG-GECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQL 480
Query: 489 RNYAGGYRCDCPVGTVRSP 545
+C C G SP
Sbjct: 481 PQSITKMQCCCDAGRCWSP 499
Score = 80.6 bits (190), Expect = 3e-15
Identities = 41/118 (34%), Positives = 55/118 (46%), Gaps = 5/118 (4%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCR--TGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECS 278
PC+ Y LC G+ + D+DEC+ CQ C NT GS++C
Sbjct: 1704 PCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCR 1763
Query: 279 CEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
C GY D C D+NEC G+C PG C N +G++ C+CP Y G C+D
Sbjct: 1764 CPTGYYLNEDTRVCDDVNECETPGIC-GPGTCYNTVGNYTCICPPDYMQVNGGNNCMD 1820
Score = 80.6 bits (190), Expect = 3e-15
Identities = 40/105 (38%), Positives = 52/105 (49%), Gaps = 3/105 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDE--CAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
N IG +RC C GY + + DE C CHNT GSY C+C G++ ++
Sbjct: 2714 NIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQF 2773
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CV 317
C+D++EC C CSNTEG Y C C GY + G CV
Sbjct: 2774 SGGCQDINECGSAQAPCSYGCSNTEGGYLCGCPPGYFRIGQGHCV 2818
Score = 77.4 bits (182), Expect = 3e-14
Identities = 57/183 (31%), Positives = 78/183 (42%), Gaps = 10/183 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDE----CAVRPPPCDQLCHNT--DGSYDCLCRTGYE 173
NT+G++ C+C P Y G D C +Q C +C Y
Sbjct: 1796 NTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYN 1855
Query: 174 LDEDGANCRDVDECE-RDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHE-EGV 347
+ A + ++C T +C + + G VDI+EC E GV
Sbjct: 1856 IGR--AWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLP------VDIDECREIPGV 1907
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ--APCRNYAGGYRCDC 521
C + G C+N++GSFRC CP G+ + + C D DEC CQ A C N AG YRCDC
Sbjct: 1908 CEN-GVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDC 1966
Query: 522 PVG 530
G
Sbjct: 1967 KPG 1969
Score = 77.0 bits (181), Expect = 4e-14
Identities = 60/173 (34%), Positives = 81/173 (46%), Gaps = 28/173 (16%)
Frame = +3
Query: 12 NTIGSFRCVCGPG--YRPAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDE 182
NT GSF C C G Y+P + DEC PC + +C N+ GS+ C C + LD
Sbjct: 914 NTPGSFVCTCPKGFIYKPDLKTCEDIDEC--ESSPCINGVCKNSPGSFICECSSESTLDP 971
Query: 183 DGANCRD----------VD-ECERDTHTC---QQICSNTEGSY--ECS-------CEDGY 293
C + +D CE + + Q CS+ ++ C+ C GY
Sbjct: 972 TKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGY 1031
Query: 294 EK-RGDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
+ +G C DI+EC GVC + G CVN GSF+C CP G LDA G C+D
Sbjct: 1032 SRIKGTQCEDIDECEVFPGVCKN-GLCVNTRGSFKCQCPSGMTLDATGRICLD 1083
Score = 76.6 bits (180), Expect = 5e-14
Identities = 36/87 (41%), Positives = 47/87 (54%), Gaps = 3/87 (3%)
Frame = +3
Query: 300 RGDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGR 473
R AC D++EC G+C G C+N +GSF C CP G++L+ +C D DEC+ G
Sbjct: 371 RTGACQDVDECQAIPGLCQG-GNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGI 429
Query: 474 CQ-APCRNYAGGYRCDCPVGTVRSPSG 551
C+ C N Y C CP G SP G
Sbjct: 430 CEGGECTNTVSSYFCKCPPGFYTSPDG 456
Score = 71.7 bits (168), Expect = 2e-12
Identities = 53/178 (29%), Positives = 72/178 (40%), Gaps = 6/178 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDE 182
VNT GS+ C C P + V D R C D +G C G + +
Sbjct: 1634 VNTPGSYICDCPPDFELNPTRVGCVD---TRSGNCYLDIRPRGDNGDTACSNEIGVGVSK 1690
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV--DINECHE-EGVCP 353
C C + + +E C +G+ + DI+EC E G+C
Sbjct: 1691 ASCCCSLGKAWGTPCEMCPAV-NTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQ 1749
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCP 524
G+C+N GSF+C CP GY L+ + C D +EC G C C N G Y C CP
Sbjct: 1750 G-GKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICP 1806
Score = 70.1 bits (164), Expect = 5e-12
Identities = 44/112 (39%), Positives = 56/112 (50%), Gaps = 7/112 (6%)
Frame = +3
Query: 9 VNTIGSFRCVC--GPGYRPAGRGV--RGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYE 173
VNT ++ +C G G+RP V DEC P C C NT GS+ C C TGY
Sbjct: 1711 VNT-SEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYY 1769
Query: 174 LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK--RGDACVDI 323
L+ED C DV+ECE C NT G+Y C C Y + G+ C+D+
Sbjct: 1770 LNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDM 1821
Score = 69.3 bits (162), Expect = 8e-12
Identities = 41/119 (34%), Positives = 55/119 (46%), Gaps = 10/119 (8%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ-QICSNT 257
DEC P C C NT GS++C C G++L+E C D+DEC C+ C+NT
Sbjct: 379 DECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNT 438
Query: 258 EGSYECSCEDGY--EKRGDACVDINE--CHEEGVCPSPGRCVNLL----GSFRCVCPRG 410
SY C C G+ G C+D+ C+ + GRC N L +C C G
Sbjct: 439 VSSYFCKCPPGFYTSPDGTRCIDVRPGYCY---TALTNGRCSNQLPQSITKMQCCCDAG 494
Score = 63.3 bits (147), Expect = 5e-10
Identities = 54/184 (29%), Positives = 74/184 (40%), Gaps = 10/184 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGR---GVRGRDECAVR--PPPCDQLCHNTDGSYDCLCRTG 167
VNT GSF+C C G GR +R + C +R C C C G
Sbjct: 1058 VNTRGSFKCQCPSGMTLDATGRICLDIR-LETCFLRYEDEECTLPIAGRHRMDACCCSVG 1116
Query: 168 YELDEDGANCRDVDECE-RDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEG 344
+ + +EC R+T +++C G +G DINEC
Sbjct: 1117 AAWGTE-----ECEECPMRNTPEYEELCPRGPGFATKEITNG----KPFFKDINECKMIP 1167
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC-QAPCRNYAGGYRCD 518
+ G+C N +GSF+C C G+ LD+E C D DEC C + C N G + C
Sbjct: 1168 SLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECK 1227
Query: 519 CPVG 530
C G
Sbjct: 1228 CDEG 1231
Score = 58.4 bits (135), Expect = 2e-08
Identities = 24/57 (42%), Positives = 31/57 (54%)
Frame = +3
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
GRC+ GS+RC C +G++LD G C+D DEC + C N G Y C C G
Sbjct: 594 GRCIPTPGSYRCECNKGFQLDLRG-ECIDVDECEKNPCAGGECINNQGSYTCQCRAG 649
Score = 55.6 bits (128), Expect = 1e-07
Identities = 40/135 (29%), Positives = 51/135 (37%), Gaps = 4/135 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCD-QLCHNTDGSYDCLCRTGYELD 179
+NT+GSF C C G++ + DEC+ P C+ C NT SY C C G+
Sbjct: 394 INTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTS 453
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSP 359
DG C DV T CSN K C D C GV +P
Sbjct: 454 PDGTRCIDVRPGYCYTALTNGRCSN-------QLPQSITKM-QCCCDAGRCWSPGVTVAP 505
Query: 360 GRC-VNLLGSFRCVC 401
C + F +C
Sbjct: 506 EMCPIRATEDFNKLC 520
Score = 54.8 bits (126), Expect = 2e-07
Identities = 52/178 (29%), Positives = 66/178 (37%), Gaps = 13/178 (7%)
Frame = +3
Query: 36 VCGPGY-RPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDV- 206
+CG GY R G DEC V P C LC NT GS+ C C +G LD G C D+
Sbjct: 1026 ICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIR 1085
Query: 207 -DEC--ERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNL 377
+ C + C + C C G A EC E CP +
Sbjct: 1086 LETCFLRYEDEECTLPIAGRHRMDACCCSVG------AAWGTEECEE---CP-----MRN 1131
Query: 378 LGSFRCVCPRGYRLDAEGAR-----CVDRDECAQ-TGRC-QAPCRNYAGGYRCDCPVG 530
+ +CPRG + D +EC C CRN G ++C C G
Sbjct: 1132 TPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSG 1189
Score = 33.9 bits (74), Expect = 0.38
Identities = 40/144 (27%), Positives = 56/144 (38%), Gaps = 6/144 (4%)
Frame = +3
Query: 3 RGVNTIGS-FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYD--CLCRTGYE 173
+G N GS + C PG++ + G ++C V P C C + S C C +G
Sbjct: 185 KGPNVCGSRYNAYCCPGWKT----LPGGNQCIV--PICRHSCGDGFCSRPNMCTCPSGQI 238
Query: 174 LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC---VDINECHEEG 344
G+ R + C C S ++ C C+ GY G C V + C G
Sbjct: 239 APSCGS--RSIQHCNI---RCMNGGSCSDD--HCLCQKGYI--GTHCGQPVCESGCLNGG 289
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYR 416
C +P RC G C R YR
Sbjct: 290 RCVAPNRCACTYGFTGPQCERDYR 313
>L13923-1|AAB02036.1| 2871|Homo sapiens fibrillin protein.
Length = 2871
Score = 192 bits (467), Expect = 9e-49
Identities = 82/177 (46%), Positives = 102/177 (57%), Gaps = 3/177 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRP--AGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN GS+ C+C GY P G +EC P PC+ +C NT+GSY C C GY L E
Sbjct: 2419 VNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQE 2478
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEE-GVCPSP 359
DG +C+D+DEC H CQ +C NT G + C C G+ + +C+D NEC + +C S
Sbjct: 2479 DGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSK 2538
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
G C N GSF C C RG+ LD G+ C D DEC RCQ C+N GGYRC CP G
Sbjct: 2539 GICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQHGCQNIIGGYRCSCPQG 2595
Score = 157 bits (380), Expect = 3e-38
Identities = 79/187 (42%), Positives = 101/187 (54%), Gaps = 9/187 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD- 179
NTIGSF+C C G+ R DEC + P C + C NT G ++C C GYE
Sbjct: 1046 NTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGF 1105
Query: 180 EDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEG-V 347
NC D+DEC+RD C+ +C NTEGSY C C G++ + AC+DINEC +
Sbjct: 1106 MMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHL 1165
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRCDCP 524
CP+ GRCVNL+G ++C C GY + CVD DEC+ G C+ C N G Y C C
Sbjct: 1166 CPN-GRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQ 1224
Query: 525 VGTVRSP 545
G P
Sbjct: 1225 PGFALMP 1231
Score = 156 bits (378), Expect = 6e-38
Identities = 75/186 (40%), Positives = 96/186 (51%), Gaps = 5/186 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDE 182
VNTIG F C C PG+ +EC C +C NT GS+ C C+ G+ LD+
Sbjct: 2501 VNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQ 2560
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK--RGDACVDINECHEEGVCPS 356
G++C DVDECE + H CQ C N G Y CSC GY + + + CVD NEC +C
Sbjct: 2561 TGSSCEDVDECEGN-HRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGG 2619
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQT-GRCQAPCRNYAGGYRCDCPVGT 533
C N LGS++C+CP G++ + C D +EC C C N GGY C CP G
Sbjct: 2620 AS-CHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGCSNTEGGYLCGCPPGY 2678
Query: 534 VRSPSG 551
R G
Sbjct: 2679 FRIGQG 2684
Score = 152 bits (368), Expect = 9e-37
Identities = 75/180 (41%), Positives = 100/180 (55%), Gaps = 6/180 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRG-VRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
+NT GS+RC C PGYR G R+EC P C C +T GS+ CLC TG++ ++
Sbjct: 1825 INTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTND 1884
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY-EKRGDACVDINECHE-EGVCPS 356
D C D++ECERD C NT GS+ C C G+ + C+D++EC G
Sbjct: 1885 DQTMCLDINECERDA-CGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCR 1943
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRCDCPVG 530
G+C+N +GSF+C C GY + +G CVD +EC R AP C+N G YRC CP G
Sbjct: 1944 NGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPG 2003
Score = 147 bits (355), Expect = 3e-35
Identities = 76/177 (42%), Positives = 88/177 (49%), Gaps = 6/177 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELDED 185
NT GSF+C C PG+ G DEC+ C Q C NT GSY CLC+ GY D
Sbjct: 1341 NTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYT--GD 1398
Query: 186 GANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPS 356
G C D+DEC + + C C N G Y C C+ G+ D AC DI+EC +C
Sbjct: 1399 GFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVF 1458
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCP 524
G C NL G FRC C GY LD G C D +EC C C N G Y CDCP
Sbjct: 1459 -GTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYICDCP 1514
Score = 143 bits (346), Expect = 4e-34
Identities = 73/187 (39%), Positives = 94/187 (50%), Gaps = 7/187 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELD 179
NT GSF C C GY + G +EC + C + +C NT GS+ C C G+
Sbjct: 1298 NTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWI-- 1355
Query: 180 EDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCP 353
DG C D+DEC TH C Q C NT GSY C C++GY G C D++EC E
Sbjct: 1356 GDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLC 1415
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ-APCRNYAGGYRCDCPVG 530
G+C+N G +RC C G+ A+G C D DEC+ C C N G +RC+C +G
Sbjct: 1416 GNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIG 1475
Query: 531 TVRSPSG 551
SG
Sbjct: 1476 YELDRSG 1482
Score = 141 bits (341), Expect = 2e-33
Identities = 68/180 (37%), Positives = 96/180 (53%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT GS++C C GY + GR + DECA + C LC NT G + C C G+ +
Sbjct: 2461 NTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFT--QH 2518
Query: 186 GANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGY--EKRGDACVDINECHEEGVCP 353
+C D +EC D + C + IC NT GS+ C C+ G+ ++ G +C D++EC C
Sbjct: 2519 HTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQ 2578
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPVG 530
C N++G +RC CP+GY + +CVD +EC C A C N G Y+C CP G
Sbjct: 2579 HG--CQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAG 2636
Score = 139 bits (337), Expect = 5e-33
Identities = 72/187 (38%), Positives = 94/187 (50%), Gaps = 9/187 (4%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
R VN IG ++C C PGY P DEC++ C+ C N++GSY+C C+ G+ L
Sbjct: 1170 RCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFAL 1229
Query: 177 DEDGANCRDVDECERDTHTCQ-QICSNTEGSYECSCEDGYEKRGD--ACVDINECH-EEG 344
D +C D+DECE + + C C+N G Y C C DG+ D CVD+NEC
Sbjct: 1230 MPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPN 1289
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC---AQTGRCQAPCRNYAGGYRC 515
+C S G C N GSF C C GY C D +EC A A C N AG ++C
Sbjct: 1290 ICLS-GTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKC 1348
Query: 516 DCPVGTV 536
C G +
Sbjct: 1349 SCSPGWI 1355
Score = 139 bits (336), Expect = 7e-33
Identities = 69/188 (36%), Positives = 97/188 (51%), Gaps = 8/188 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDE 182
N G +RC+C G+ + + +EC + P C C NT GS+ C C GY +
Sbjct: 1256 NIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKK 1315
Query: 183 DGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGDACVDINEC-HEEGVCP 353
C D++ECE H C +C+NT GS++CSC G+ G C D++EC + +C
Sbjct: 1316 GKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCS 1375
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQT-GRC-QAPCRNYAGGYRCDCPV 527
C N +GS+RC+C GY +G C D DEC++ C C N GGYRC+C +
Sbjct: 1376 QHADCKNTMGSYRCLCKEGY--TGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDM 1433
Query: 528 GTVRSPSG 551
G V S G
Sbjct: 1434 GFVPSADG 1441
Score = 138 bits (334), Expect = 1e-32
Identities = 71/186 (38%), Positives = 94/186 (50%), Gaps = 6/186 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+NT GS+RC C GY AG DEC+V P + C N G ++C C G+E
Sbjct: 2143 INTDGSYRCECPFGYTLAGNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFE-PGPM 2201
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHE--EGVCPS 356
C D++EC ++ C C NT GSYEC C GY R D C D +EC E
Sbjct: 2202 MTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEK 2261
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQ-APCRNYAGGYRCDCPVG 530
C NL+G++ C+C GY+ +G CVD +EC + G C+ C N G Y C+C G
Sbjct: 2262 QMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDG 2321
Query: 531 TVRSPS 548
SP+
Sbjct: 2322 FTASPN 2327
Score = 137 bits (332), Expect = 2e-32
Identities = 69/178 (38%), Positives = 95/178 (53%), Gaps = 5/178 (2%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRG-VRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELD 179
R + T GS+RC C G++ RG DEC P + C N GSY C CR GY+
Sbjct: 464 RCIPTPGSYRCECNKGFQLDLRGECIDVDECEKNPCAGGE-CINNQGSYTCQCRAGYQST 522
Query: 180 EDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVC 350
CRD+DEC ++ C C NT+GS+ C C G+ + G C D++EC +C
Sbjct: 523 LTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMC 582
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDC 521
+ G C+N GSF+C+C G++L ++G C D +EC G C C N G YRC+C
Sbjct: 583 LN-GMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCEC 639
Score = 136 bits (328), Expect = 6e-32
Identities = 75/188 (39%), Positives = 98/188 (52%), Gaps = 7/188 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDED 185
++T+GSF C+C G++ D C C NT GS++C C G+ L +
Sbjct: 1866 IDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHN 1925
Query: 186 GANCRDVDECERDT-HTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCP 353
+C DVDEC + C+ C NT GS++C C +GYE D CVDINEC E
Sbjct: 1926 N-DCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKC 1984
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQA--PCRNYAGGYRCDCPV 527
+PG C NL GS+RC+CP GY L E +C D DEC + A C N G ++C CP
Sbjct: 1985 APGTCQNLDGSYRCICPPGYSLQNE--KCEDIDECVEEPEICALGTCSNTEGSFKCLCPE 2042
Query: 528 GTVRSPSG 551
G S SG
Sbjct: 2043 GFSLSSSG 2050
Score = 130 bits (313), Expect = 4e-30
Identities = 65/180 (36%), Positives = 88/180 (48%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
NT GS+RC C PG++ P +EC + C C N G Y C C GY
Sbjct: 1131 NTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTP 1190
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPS 356
D C D+DEC C+ C+N+EGSYECSC+ G+ D +C DI+EC +
Sbjct: 1191 DRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICD 1250
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC-QAPCRNYAGGYRCDCPVG 530
G+C N+ G +RC+C G+ + CVD +EC C C N G + C C +G
Sbjct: 1251 GGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMG 1310
Score = 130 bits (313), Expect = 4e-30
Identities = 65/155 (41%), Positives = 80/155 (51%), Gaps = 7/155 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGV-RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
N IG F C C G+ P +ECA P C C NT GSY+C C GY L ED
Sbjct: 2183 NVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDR 2242
Query: 189 ANCRDVDECERDTHTC---QQICSNTEGSYECSCEDGYEKR--GDACVDINECH-EEGVC 350
C+D DECE H C Q C N G+Y C C GY++R G+ CVD NEC + G+C
Sbjct: 2243 RMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGIC 2302
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE 455
+ GRC+N GS+ C C G+ C+D E
Sbjct: 2303 EN-GRCLNTRGSYTCECNDGFTASPNQDECLDNRE 2336
Score = 127 bits (307), Expect = 2e-29
Identities = 67/182 (36%), Positives = 90/182 (49%), Gaps = 11/182 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD 179
+N GS+ C C GY+ RD EC C+ C NTDGS+ C+C G+ +
Sbjct: 505 INNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVT 564
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCP 353
DG NC D+DEC +C N +GS++C C+ G++ D C DINEC G+C
Sbjct: 565 RDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICM 624
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVD---RDEC---AQTGRCQAPCRNYAGGYRC 515
+ GRCVN GS+RC C G + +G CVD R C + G+C P C
Sbjct: 625 N-GRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSEC 683
Query: 516 DC 521
C
Sbjct: 684 CC 685
Score = 126 bits (304), Expect = 5e-29
Identities = 72/188 (38%), Positives = 89/188 (47%), Gaps = 10/188 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA---GRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYEL 176
VNT G F C C GY + DEC P C +CHNT+GSY C C G++L
Sbjct: 1087 VNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQL 1146
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECH-EEG 344
+ + C D++ECE H C C N G Y+C+C GY D CVDI+EC G
Sbjct: 1147 SPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNG 1206
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQ-APCRNYAGGYRCD 518
C + C N GS+ C C G+ L + C D DEC C C N G YRC
Sbjct: 1207 GCET--FCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCL 1264
Query: 519 CPVGTVRS 542
C G + S
Sbjct: 1265 CYDGFMAS 1272
Score = 126 bits (304), Expect = 5e-29
Identities = 68/179 (37%), Positives = 88/179 (49%), Gaps = 9/179 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA-GRGVRGRDECAV-RPPPC-DQLCHNTDGSYDCLCRTGYELDE 182
NTIGSF C C G+ + DECA C + C NT GS+ C C GYE+
Sbjct: 1907 NTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAP 1966
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSP 359
DG C D++EC + C C N +GSY C C GY + + C DI+EC EE +
Sbjct: 1967 DGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEICAL 2026
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVD--RDEC---AQTGRCQAPCRNYAGGYRCDC 521
G C N GSF+C+CP G+ L + G RC D C + G+C +P C C
Sbjct: 2027 GTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCC 2085
Score = 122 bits (294), Expect = 8e-28
Identities = 65/173 (37%), Positives = 91/173 (52%), Gaps = 7/173 (4%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C G G+ G + DEC V C + C N GSY C+C+TGY D G +C D++
Sbjct: 2390 CPHGRGFMTNGADI---DECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLN 2446
Query: 210 ECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINEC-HEEGVCPSPGRCVNLL 380
EC + C IC NTEGSY+CSC GY ++ G +C D++EC ++ C CVN +
Sbjct: 2447 ECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQF--LCVNTI 2504
Query: 381 GSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC--QAPCRNYAGGYRCDCPVG 530
G F C CP G+ C+D +EC + C + C+N G + C+C G
Sbjct: 2505 GGFTCKCPPGF--TQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRG 2555
Score = 122 bits (293), Expect = 1e-27
Identities = 60/161 (37%), Positives = 84/161 (52%), Gaps = 7/161 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNT 257
+EC + P C C NT GS+ C C +G+ LD + NC D+DEC C + C NT
Sbjct: 1030 NECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNT 1089
Query: 258 EGSYECSCEDGYEK---RGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAE 428
G +EC C++GYE C+DI+EC + + G C N GS+RC CP G++L
Sbjct: 1090 PGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPN 1149
Query: 429 GARCVDRDECAQTGR-C-QAPCRNYAGGYRCDCPVGTVRSP 545
+ C+D +EC + C C N G Y+C C G +P
Sbjct: 1150 ISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTP 1190
Score = 117 bits (282), Expect = 2e-26
Identities = 72/191 (37%), Positives = 93/191 (48%), Gaps = 10/191 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPG--YRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYEL 176
+N +GSFRC C G Y DEC P C + C NT GSY C C+ GY
Sbjct: 1783 INMVGSFRCECPVGFFYNDKLLVCEDIDECQ-NGPVCQRNAECINTAGSYRCDCKPGYRF 1841
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGV 347
G C D +EC+ + C C +T GS+ C C G++ D C+DINEC E
Sbjct: 1842 TSTG-QCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINEC-ERDA 1899
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGR-CQ-APCRNYAGGYRCD 518
C + G C N +GSF C C G+ L + C+D DECA G C+ C N G ++C
Sbjct: 1900 CGN-GTCRNTIGSFNCRCNHGFIL-SHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQ 1957
Query: 519 CPVGTVRSPSG 551
C G +P G
Sbjct: 1958 CNEGYEVAPDG 1968
Score = 117 bits (281), Expect = 3e-26
Identities = 57/139 (41%), Positives = 74/139 (53%), Gaps = 3/139 (2%)
Frame = +3
Query: 123 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 302
C T GSY C C G++LD G C DVDECE++ + C N +GSY C C GY+
Sbjct: 465 CIPTPGSYRCECNKGFQLDLRG-ECIDVDECEKNPCAGGE-CINNQGSYTCQCRAGYQST 522
Query: 303 --GDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC 476
C DI+EC + G + GRC+N GSF CVC G+ + +G C D DEC+ C
Sbjct: 523 LTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMC 582
Query: 477 -QAPCRNYAGGYRCDCPVG 530
C N G ++C C G
Sbjct: 583 LNGMCINEDGSFKCICKPG 601
Score = 117 bits (281), Expect = 3e-26
Identities = 67/162 (41%), Positives = 78/162 (48%), Gaps = 6/162 (3%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTE 260
DEC P C C NTDGSY C C GY L G C D DEC C N
Sbjct: 2129 DECK-EPDVCKHGQCINTDGSYRCECPFGYTLA--GNECVDTDECSVGNPCGNGTCKNVI 2185
Query: 261 GSYECSCEDGYEKRGD-ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGAR 437
G +EC+CE+G+E C DINEC + + + RCVN GS+ C CP GY L +
Sbjct: 2186 GGFECTCEEGFEPGPMMTCEDINECAQNPLLCA-FRCVNTYGSYECKCPVGYVLREDRRM 2244
Query: 438 CVDRDECAQTGR-C---QAPCRNYAGGYRCDCPVGTVRSPSG 551
C D DEC + C Q C+N G Y C C G R P G
Sbjct: 2245 CKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDG 2286
Score = 116 bits (279), Expect = 6e-26
Identities = 61/163 (37%), Positives = 76/163 (46%), Gaps = 3/163 (1%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDG 188
NT+GS+RC+C GY G DEC+ C C N G Y C C G+ DG
Sbjct: 1382 NTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADG 1441
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPSPG 362
C D+DEC C N G + C CE GYE + G C D+NEC + C S G
Sbjct: 1442 KACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCIS-G 1500
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCR 491
CVN GS+ C CP + L+ CVD ++G C R
Sbjct: 1501 NCVNTPGSYICDCPPDFELNPTRVGCVD----TRSGNCYLDIR 1539
Score = 113 bits (273), Expect = 3e-25
Identities = 57/158 (36%), Positives = 82/158 (51%), Gaps = 5/158 (3%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQI--CSN 254
DEC P C+ +C N GS+ C C G+ ++ C D+DEC+ CQ+ C N
Sbjct: 1768 DECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGP-VCQRNAECIN 1826
Query: 255 TEGSYECSCEDGYEKRGDA-CVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAE 428
T GSY C C+ GY C D NEC E +C S G+C++ +GSF C+C G++ + +
Sbjct: 1827 TAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNIC-SHGQCIDTVGSFYCLCHTGFKTNDD 1885
Query: 429 GARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVRS 542
C+D +EC + CRN G + C C G + S
Sbjct: 1886 QTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILS 1923
Score = 112 bits (270), Expect = 7e-25
Identities = 72/215 (33%), Positives = 93/215 (43%), Gaps = 35/215 (16%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
N IG++ C+CGPGY RP G G +EC +P C+ C NT GSY C C G+
Sbjct: 2267 NLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASP 2326
Query: 183 DGANCRDVDECERDTHTCQQICS------NTEGSYECSCED--GYEKRGDAC-------- 314
+ C D E T Q +C N EC C+ G+ + C
Sbjct: 2327 NQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAF 2386
Query: 315 --------------VDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR 449
DI+EC VC + G CVN GS+ C+C GY D G CVD
Sbjct: 2387 KKLCPHGRGFMTNGADIDECKVIHDVCRN-GECVNDRGSYHCICKTGYTPDITGTSCVDL 2445
Query: 450 DECAQTGR-CQAPCRNYAGGYRCDCPVGTVRSPSG 551
+EC Q + C C+N G Y+C CP G + G
Sbjct: 2446 NECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDG 2480
Score = 109 bits (261), Expect = 8e-24
Identities = 61/158 (38%), Positives = 83/158 (52%), Gaps = 9/158 (5%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C GPG AG + +ECA+ P C +C N G+Y C+C +GYE+D G NC D++
Sbjct: 711 CSSGPGMTSAGSDI---NECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDIN 767
Query: 210 ECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLL 380
EC ++ C C NT GS+ C+C G+ + D C DI+EC E C + G C N
Sbjct: 768 ECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDEC-ESSPCIN-GVCKNSP 825
Query: 381 GSFRCVCPRGYRLDAEGARCVD--RDECAQT---GRCQ 479
GSF C C LD C++ + C QT GRC+
Sbjct: 826 GSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCE 863
Score = 103 bits (248), Expect = 3e-22
Identities = 51/150 (34%), Positives = 69/150 (46%), Gaps = 3/150 (2%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCE 284
PC Y LC +G + G+ D++EC D C IC N G+Y+C C
Sbjct: 695 PCQPCPAQNSAEYQALCSSGPGMTSAGS---DINECALDPDICPNGICENLRGTYKCICN 751
Query: 285 DGYE--KRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC 458
GYE G CVDINEC + G+C N GSF C CP+G+ + C D DEC
Sbjct: 752 SGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDEC 811
Query: 459 AQTGRCQAPCRNYAGGYRCDCPVGTVRSPS 548
+ C+N G + C+C + P+
Sbjct: 812 ESSPCINGVCKNSPGSFICECSSESTLDPT 841
Score = 96.7 bits (230), Expect = 5e-20
Identities = 44/110 (40%), Positives = 60/110 (54%), Gaps = 4/110 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
R +NT GSF CVC G+ G+ DEC++R + +C N DGS+ C+C+ G++L
Sbjct: 545 RCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQL 604
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVD 320
DG C+D++ECE C NT+GSY C C G G CVD
Sbjct: 605 ASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVD 654
Score = 95.5 bits (227), Expect = 1e-19
Identities = 53/147 (36%), Positives = 69/147 (46%), Gaps = 4/147 (2%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCRTGYEL---DEDGANCRDVDECERDTHTCQQICSNTEGSYECS 278
PC+ D ++ +C G + +D A D+DEC+ C NT+GSY C
Sbjct: 2095 PCELCPTEPDEAFRQICPYGSGIIVGPDDSAV--DMDECKEPDVCKHGQCINTDGSYRCE 2152
Query: 279 CEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC 458
C GY G+ CVD +EC C + G C N++G F C C G+ C D +EC
Sbjct: 2153 CPFGYTLAGNECVDTDECSVGNPCGN-GTCKNVIGGFECTCEEGFE-PGPMMTCEDINEC 2210
Query: 459 AQTG-RCQAPCRNYAGGYRCDCPVGTV 536
AQ C C N G Y C CPVG V
Sbjct: 2211 AQNPLLCAFRCVNTYGSYECKCPVGYV 2237
Score = 89.0 bits (211), Expect = 1e-17
Identities = 68/216 (31%), Positives = 89/216 (41%), Gaps = 42/216 (19%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+N G +RC C G+ P+ G+ DEC++ CHN G + C C GYELD
Sbjct: 1421 LNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDR 1480
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE-----------KRGDACVDI-- 323
G NC DV+EC T C NT GSY C C +E + G+ +DI
Sbjct: 1481 SGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRP 1540
Query: 324 ------NECHEE-GVCPSPGRCVNLLG----------------SFRCVCP--RGYRLDAE 428
C E GV S C LG ++ +CP G+R +
Sbjct: 1541 RGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPI 1600
Query: 429 GARCVDRDECAQ-TGRCQ-APCRNYAGGYRCDCPVG 530
D DEC + G CQ C N G ++C CP G
Sbjct: 1601 TVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTG 1636
Score = 87.4 bits (207), Expect = 3e-17
Identities = 57/179 (31%), Positives = 79/179 (44%), Gaps = 7/179 (3%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVR-PPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C C G A G +EC +R P ++LC G E+ +D++
Sbjct: 980 CCCSVG---AAWGTEECEECPMRNTPEYEELCPRGPGF------ATKEITNGKPFFKDIN 1030
Query: 210 ECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLL 380
EC+ C C NT GS++C C+ G+ + C DI+EC G+CVN
Sbjct: 1031 ECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTP 1090
Query: 381 GSFRCVCPRGYRLDAEGAR-CVDRDECAQTGR-CQAP-CRNYAGGYRCDCPVGTVRSPS 548
G F C C GY + C+D DEC + C+ C N G YRC+CP G SP+
Sbjct: 1091 GDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPN 1149
Score = 85.0 bits (201), Expect = 2e-16
Identities = 61/209 (29%), Positives = 91/209 (43%), Gaps = 29/209 (13%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
N G+++C+C GY G+ +EC + CD C NT GS+ C C G+
Sbjct: 741 NLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKP 800
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSY--ECSCEDGYEKRGDACVDI--NECHE---E 341
D C D+DECE + +C N+ GS+ ECS E + C++ C + +
Sbjct: 801 DLKTCEDIDECE-SSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVID 859
Query: 342 GVC-------PSPGRCVNLLGS---FRC-------VCPRGYRLDAEGARCVDRDEC-AQT 467
G C +C + LG+ C +C +GY +G +C D DEC
Sbjct: 860 GRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYS-RIKGTQCEDIDECEVFP 918
Query: 468 GRCQ-APCRNYAGGYRCDCPVGTVRSPSG 551
G C+ C N G ++C CP G +G
Sbjct: 919 GVCKNGLCVNTRGSFKCQCPSGMTLDATG 947
Score = 84.6 bits (200), Expect = 2e-16
Identities = 52/149 (34%), Positives = 65/149 (43%), Gaps = 13/149 (8%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQL---CHNTDGSYDCLCRTG 167
R VNT GS+ C C GY R R + DEC C + C N G+Y C+C G
Sbjct: 2220 RCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPG 2279
Query: 168 YELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGY--EKRGDACVDINE--C 332
Y+ DG C D +EC+ C+ C NT GSY C C DG+ D C+D E C
Sbjct: 2280 YQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYC 2339
Query: 333 HEE---GVCPSPGRCVNLLGSFRCVCPRG 410
E +C N + C C G
Sbjct: 2340 FTEVLQNMCQIGSSNRNPVTKSECCCDGG 2368
Score = 83.4 bits (197), Expect = 5e-16
Identities = 49/139 (35%), Positives = 64/139 (46%), Gaps = 9/139 (6%)
Frame = +3
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKR--GDACVDIN 326
CR G+ + C+DVDEC+ CQ C NT GS+EC C G++ C DI+
Sbjct: 231 CRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDID 290
Query: 327 ECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD-RDECAQT----GRCQAPC 488
EC G+C G C N + S+ C CP G+ +G RC+D R T GRC
Sbjct: 291 ECSTIPGICEG-GECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQL 349
Query: 489 RNYAGGYRCDCPVGTVRSP 545
+C C G SP
Sbjct: 350 PQSITKMQCCCDAGRCWSP 368
Score = 80.6 bits (190), Expect = 3e-15
Identities = 41/118 (34%), Positives = 55/118 (46%), Gaps = 5/118 (4%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCR--TGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECS 278
PC+ Y LC G+ + D+DEC+ CQ C NT GS++C
Sbjct: 1573 PCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCR 1632
Query: 279 CEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
C GY D C D+NEC G+C PG C N +G++ C+CP Y G C+D
Sbjct: 1633 CPTGYYLNEDTRVCDDVNECETPGIC-GPGTCYNTVGNYTCICPPDYMQVNGGNNCMD 1689
Score = 80.6 bits (190), Expect = 3e-15
Identities = 40/105 (38%), Positives = 52/105 (49%), Gaps = 3/105 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDE--CAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
N IG +RC C GY + + DE C CHNT GSY C+C G++ ++
Sbjct: 2583 NIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQF 2642
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CV 317
C+D++EC C CSNTEG Y C C GY + G CV
Sbjct: 2643 SGGCQDINECGSAQAPCSYGCSNTEGGYLCGCPPGYFRIGQGHCV 2687
Score = 77.4 bits (182), Expect = 3e-14
Identities = 57/183 (31%), Positives = 78/183 (42%), Gaps = 10/183 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDE----CAVRPPPCDQLCHNT--DGSYDCLCRTGYE 173
NT+G++ C+C P Y G D C +Q C +C Y
Sbjct: 1665 NTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYN 1724
Query: 174 LDEDGANCRDVDECE-RDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHE-EGV 347
+ A + ++C T +C + + G VDI+EC E GV
Sbjct: 1725 IGR--AWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLP------VDIDECREIPGV 1776
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ--APCRNYAGGYRCDC 521
C + G C+N++GSFRC CP G+ + + C D DEC CQ A C N AG YRCDC
Sbjct: 1777 CEN-GVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDC 1835
Query: 522 PVG 530
G
Sbjct: 1836 KPG 1838
Score = 77.0 bits (181), Expect = 4e-14
Identities = 60/173 (34%), Positives = 81/173 (46%), Gaps = 28/173 (16%)
Frame = +3
Query: 12 NTIGSFRCVCGPG--YRPAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDE 182
NT GSF C C G Y+P + DEC PC + +C N+ GS+ C C + LD
Sbjct: 783 NTPGSFVCTCPKGFIYKPDLKTCEDIDEC--ESSPCINGVCKNSPGSFICECSSESTLDP 840
Query: 183 DGANCRD----------VD-ECERDTHTC---QQICSNTEGSY--ECS-------CEDGY 293
C + +D CE + + Q CS+ ++ C+ C GY
Sbjct: 841 TKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGY 900
Query: 294 EK-RGDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
+ +G C DI+EC GVC + G CVN GSF+C CP G LDA G C+D
Sbjct: 901 SRIKGTQCEDIDECEVFPGVCKN-GLCVNTRGSFKCQCPSGMTLDATGRICLD 952
Score = 76.6 bits (180), Expect = 5e-14
Identities = 36/87 (41%), Positives = 47/87 (54%), Gaps = 3/87 (3%)
Frame = +3
Query: 300 RGDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGR 473
R AC D++EC G+C G C+N +GSF C CP G++L+ +C D DEC+ G
Sbjct: 240 RTGACQDVDECQAIPGLCQG-GNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGI 298
Query: 474 CQ-APCRNYAGGYRCDCPVGTVRSPSG 551
C+ C N Y C CP G SP G
Sbjct: 299 CEGGECTNTVSSYFCKCPPGFYTSPDG 325
Score = 71.7 bits (168), Expect = 2e-12
Identities = 53/178 (29%), Positives = 72/178 (40%), Gaps = 6/178 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDE 182
VNT GS+ C C P + V D R C D +G C G + +
Sbjct: 1503 VNTPGSYICDCPPDFELNPTRVGCVD---TRSGNCYLDIRPRGDNGDTACSNEIGVGVSK 1559
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV--DINECHE-EGVCP 353
C C + + +E C +G+ + DI+EC E G+C
Sbjct: 1560 ASCCCSLGKAWGTPCEMCPAV-NTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQ 1618
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCP 524
G+C+N GSF+C CP GY L+ + C D +EC G C C N G Y C CP
Sbjct: 1619 G-GKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICP 1675
Score = 70.1 bits (164), Expect = 5e-12
Identities = 44/112 (39%), Positives = 56/112 (50%), Gaps = 7/112 (6%)
Frame = +3
Query: 9 VNTIGSFRCVC--GPGYRPAGRGV--RGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYE 173
VNT ++ +C G G+RP V DEC P C C NT GS+ C C TGY
Sbjct: 1580 VNT-SEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYY 1638
Query: 174 LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK--RGDACVDI 323
L+ED C DV+ECE C NT G+Y C C Y + G+ C+D+
Sbjct: 1639 LNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDM 1690
Score = 69.3 bits (162), Expect = 8e-12
Identities = 41/119 (34%), Positives = 55/119 (46%), Gaps = 10/119 (8%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ-QICSNT 257
DEC P C C NT GS++C C G++L+E C D+DEC C+ C+NT
Sbjct: 248 DECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNT 307
Query: 258 EGSYECSCEDGY--EKRGDACVDINE--CHEEGVCPSPGRCVNLL----GSFRCVCPRG 410
SY C C G+ G C+D+ C+ + GRC N L +C C G
Sbjct: 308 VSSYFCKCPPGFYTSPDGTRCIDVRPGYCY---TALTNGRCSNQLPQSITKMQCCCDAG 363
Score = 63.3 bits (147), Expect = 5e-10
Identities = 54/184 (29%), Positives = 74/184 (40%), Gaps = 10/184 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGR---GVRGRDECAVR--PPPCDQLCHNTDGSYDCLCRTG 167
VNT GSF+C C G GR +R + C +R C C C G
Sbjct: 927 VNTRGSFKCQCPSGMTLDATGRICLDIR-LETCFLRYEDEECTLPIAGRHRMDACCCSVG 985
Query: 168 YELDEDGANCRDVDECE-RDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEG 344
+ + +EC R+T +++C G +G DINEC
Sbjct: 986 AAWGTE-----ECEECPMRNTPEYEELCPRGPGFATKEITNG----KPFFKDINECKMIP 1036
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC-QAPCRNYAGGYRCD 518
+ G+C N +GSF+C C G+ LD+E C D DEC C + C N G + C
Sbjct: 1037 SLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECK 1096
Query: 519 CPVG 530
C G
Sbjct: 1097 CDEG 1100
Score = 58.4 bits (135), Expect = 2e-08
Identities = 24/57 (42%), Positives = 31/57 (54%)
Frame = +3
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
GRC+ GS+RC C +G++LD G C+D DEC + C N G Y C C G
Sbjct: 463 GRCIPTPGSYRCECNKGFQLDLRG-ECIDVDECEKNPCAGGECINNQGSYTCQCRAG 518
Score = 55.6 bits (128), Expect = 1e-07
Identities = 40/135 (29%), Positives = 51/135 (37%), Gaps = 4/135 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCD-QLCHNTDGSYDCLCRTGYELD 179
+NT+GSF C C G++ + DEC+ P C+ C NT SY C C G+
Sbjct: 263 INTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTS 322
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSP 359
DG C DV T CSN K C D C GV +P
Sbjct: 323 PDGTRCIDVRPGYCYTALTNGRCSN-------QLPQSITKM-QCCCDAGRCWSPGVTVAP 374
Query: 360 GRC-VNLLGSFRCVC 401
C + F +C
Sbjct: 375 EMCPIRATEDFNKLC 389
Score = 54.8 bits (126), Expect = 2e-07
Identities = 52/178 (29%), Positives = 66/178 (37%), Gaps = 13/178 (7%)
Frame = +3
Query: 36 VCGPGY-RPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDV- 206
+CG GY R G DEC V P C LC NT GS+ C C +G LD G C D+
Sbjct: 895 ICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIR 954
Query: 207 -DEC--ERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNL 377
+ C + C + C C G A EC E CP +
Sbjct: 955 LETCFLRYEDEECTLPIAGRHRMDACCCSVG------AAWGTEECEE---CP-----MRN 1000
Query: 378 LGSFRCVCPRGYRLDAEGAR-----CVDRDECAQ-TGRC-QAPCRNYAGGYRCDCPVG 530
+ +CPRG + D +EC C CRN G ++C C G
Sbjct: 1001 TPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSG 1058
Score = 33.9 bits (74), Expect = 0.38
Identities = 40/144 (27%), Positives = 56/144 (38%), Gaps = 6/144 (4%)
Frame = +3
Query: 3 RGVNTIGS-FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYD--CLCRTGYE 173
+G N GS + C PG++ + G ++C V P C C + S C C +G
Sbjct: 54 KGPNVCGSRYNAYCCPGWKT----LPGGNQCIV--PICRHSCGDGFCSRPNMCTCPSGQI 107
Query: 174 LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC---VDINECHEEG 344
G+ R + C C S ++ C C+ GY G C V + C G
Sbjct: 108 APSCGS--RSIQHCNI---RCMNGGSCSDD--HCLCQKGYI--GTHCGQPVCESGCLNGG 158
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYR 416
C +P RC G C R YR
Sbjct: 159 RCVAPNRCACTYGFTGPQCERDYR 182
>AB177803-1|BAD16739.1| 2871|Homo sapiens fibrillin 1 protein.
Length = 2871
Score = 192 bits (467), Expect = 9e-49
Identities = 82/177 (46%), Positives = 102/177 (57%), Gaps = 3/177 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRP--AGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN GS+ C+C GY P G +EC P PC+ +C NT+GSY C C GY L E
Sbjct: 2419 VNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQE 2478
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEE-GVCPSP 359
DG +C+D+DEC H CQ +C NT G + C C G+ + +C+D NEC + +C S
Sbjct: 2479 DGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSK 2538
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
G C N GSF C C RG+ LD G+ C D DEC RCQ C+N GGYRC CP G
Sbjct: 2539 GICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQHGCQNIIGGYRCSCPQG 2595
Score = 157 bits (380), Expect = 3e-38
Identities = 79/187 (42%), Positives = 101/187 (54%), Gaps = 9/187 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD- 179
NTIGSF+C C G+ R DEC + P C + C NT G ++C C GYE
Sbjct: 1046 NTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGF 1105
Query: 180 EDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEG-V 347
NC D+DEC+RD C+ +C NTEGSY C C G++ + AC+DINEC +
Sbjct: 1106 MMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHL 1165
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRCDCP 524
CP+ GRCVNL+G ++C C GY + CVD DEC+ G C+ C N G Y C C
Sbjct: 1166 CPN-GRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQ 1224
Query: 525 VGTVRSP 545
G P
Sbjct: 1225 PGFALMP 1231
Score = 155 bits (375), Expect = 1e-37
Identities = 78/189 (41%), Positives = 99/189 (52%), Gaps = 8/189 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDE 182
VNTIG F C C PG+ +EC C +C NT GS+ C C+ G+ LD+
Sbjct: 2501 VNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQ 2560
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK--RGDACVDINECHEEGVCPS 356
G++C DVDECE + H CQ C N G Y CSC GY + + + CVD NEC +C
Sbjct: 2561 TGSSCEDVDECEGN-HRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGG 2619
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPC----RNYAGGYRCDCP 524
C N LGS++C+CP G++ + C D +EC G QAPC N GGY C CP
Sbjct: 2620 AS-CHNTLGSYKCMCPAGFQYEQFSGGCQDINEC---GSAQAPCSYGSSNTEGGYLCGCP 2675
Query: 525 VGTVRSPSG 551
G R G
Sbjct: 2676 PGYFRIGQG 2684
Score = 152 bits (368), Expect = 9e-37
Identities = 75/180 (41%), Positives = 100/180 (55%), Gaps = 6/180 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRG-VRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
+NT GS+RC C PGYR G R+EC P C C +T GS+ CLC TG++ ++
Sbjct: 1825 INTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTND 1884
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY-EKRGDACVDINECHE-EGVCPS 356
D C D++ECERD C NT GS+ C C G+ + C+D++EC G
Sbjct: 1885 DQTMCLDINECERDA-CGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCR 1943
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRCDCPVG 530
G+C+N +GSF+C C GY + +G CVD +EC R AP C+N G YRC CP G
Sbjct: 1944 NGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPG 2003
Score = 147 bits (355), Expect = 3e-35
Identities = 76/177 (42%), Positives = 88/177 (49%), Gaps = 6/177 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELDED 185
NT GSF+C C PG+ G DEC+ C Q C NT GSY CLC+ GY D
Sbjct: 1341 NTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYT--GD 1398
Query: 186 GANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPS 356
G C D+DEC + + C C N G Y C C+ G+ D AC DI+EC +C
Sbjct: 1399 GFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVF 1458
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCP 524
G C NL G FRC C GY LD G C D +EC C C N G Y CDCP
Sbjct: 1459 -GTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYICDCP 1514
Score = 143 bits (346), Expect = 4e-34
Identities = 73/187 (39%), Positives = 94/187 (50%), Gaps = 7/187 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELD 179
NT GSF C C GY + G +EC + C + +C NT GS+ C C G+
Sbjct: 1298 NTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWI-- 1355
Query: 180 EDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCP 353
DG C D+DEC TH C Q C NT GSY C C++GY G C D++EC E
Sbjct: 1356 GDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLC 1415
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ-APCRNYAGGYRCDCPVG 530
G+C+N G +RC C G+ A+G C D DEC+ C C N G +RC+C +G
Sbjct: 1416 GNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIG 1475
Query: 531 TVRSPSG 551
SG
Sbjct: 1476 YELDRSG 1482
Score = 141 bits (341), Expect = 2e-33
Identities = 68/180 (37%), Positives = 96/180 (53%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT GS++C C GY + GR + DECA + C LC NT G + C C G+ +
Sbjct: 2461 NTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFT--QH 2518
Query: 186 GANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGY--EKRGDACVDINECHEEGVCP 353
+C D +EC D + C + IC NT GS+ C C+ G+ ++ G +C D++EC C
Sbjct: 2519 HTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQ 2578
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPVG 530
C N++G +RC CP+GY + +CVD +EC C A C N G Y+C CP G
Sbjct: 2579 HG--CQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAG 2636
Score = 139 bits (337), Expect = 5e-33
Identities = 72/187 (38%), Positives = 94/187 (50%), Gaps = 9/187 (4%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
R VN IG ++C C PGY P DEC++ C+ C N++GSY+C C+ G+ L
Sbjct: 1170 RCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFAL 1229
Query: 177 DEDGANCRDVDECERDTHTCQ-QICSNTEGSYECSCEDGYEKRGD--ACVDINECH-EEG 344
D +C D+DECE + + C C+N G Y C C DG+ D CVD+NEC
Sbjct: 1230 MPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPN 1289
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC---AQTGRCQAPCRNYAGGYRC 515
+C S G C N GSF C C GY C D +EC A A C N AG ++C
Sbjct: 1290 ICLS-GTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKC 1348
Query: 516 DCPVGTV 536
C G +
Sbjct: 1349 SCSPGWI 1355
Score = 139 bits (336), Expect = 7e-33
Identities = 69/188 (36%), Positives = 97/188 (51%), Gaps = 8/188 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDE 182
N G +RC+C G+ + + +EC + P C C NT GS+ C C GY +
Sbjct: 1256 NIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKK 1315
Query: 183 DGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGDACVDINEC-HEEGVCP 353
C D++ECE H C +C+NT GS++CSC G+ G C D++EC + +C
Sbjct: 1316 GKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCS 1375
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQT-GRC-QAPCRNYAGGYRCDCPV 527
C N +GS+RC+C GY +G C D DEC++ C C N GGYRC+C +
Sbjct: 1376 QHADCKNTMGSYRCLCKEGY--TGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDM 1433
Query: 528 GTVRSPSG 551
G V S G
Sbjct: 1434 GFVPSADG 1441
Score = 137 bits (332), Expect = 2e-32
Identities = 71/186 (38%), Positives = 94/186 (50%), Gaps = 6/186 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+NT GS+RC C GY AG DEC+V P + C N G ++C C G+E
Sbjct: 2143 INTDGSYRCECPFGYILAGNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFE-PGPM 2201
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHE--EGVCPS 356
C D++EC ++ C C NT GSYEC C GY R D C D +EC E
Sbjct: 2202 MTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEK 2261
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQ-APCRNYAGGYRCDCPVG 530
C NL+G++ C+C GY+ +G CVD +EC + G C+ C N G Y C+C G
Sbjct: 2262 QMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDG 2321
Query: 531 TVRSPS 548
SP+
Sbjct: 2322 FTASPN 2327
Score = 136 bits (328), Expect = 6e-32
Identities = 75/188 (39%), Positives = 98/188 (52%), Gaps = 7/188 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDED 185
++T+GSF C+C G++ D C C NT GS++C C G+ L +
Sbjct: 1866 IDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHN 1925
Query: 186 GANCRDVDECERDT-HTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCP 353
+C DVDEC + C+ C NT GS++C C +GYE D CVDINEC E
Sbjct: 1926 N-DCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKC 1984
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQA--PCRNYAGGYRCDCPV 527
+PG C NL GS+RC+CP GY L E +C D DEC + A C N G ++C CP
Sbjct: 1985 APGTCQNLDGSYRCICPPGYSLQNE--KCEDIDECVEEPEICALGTCSNTEGSFKCLCPE 2042
Query: 528 GTVRSPSG 551
G S SG
Sbjct: 2043 GFSLSSSG 2050
Score = 135 bits (327), Expect = 8e-32
Identities = 69/178 (38%), Positives = 94/178 (52%), Gaps = 5/178 (2%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRG-VRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELD 179
R + T GS RC C G++ RG DEC P + C N GSY C CR GY+
Sbjct: 464 RCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPCAGGE-CINNQGSYTCQCRAGYQST 522
Query: 180 EDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVC 350
CRD+DEC ++ C C NT+GS+ C C G+ + G C D++EC +C
Sbjct: 523 LTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMC 582
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDC 521
+ G C+N GSF+C+C G++L ++G C D +EC G C C N G YRC+C
Sbjct: 583 LN-GMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCEC 639
Score = 130 bits (313), Expect = 4e-30
Identities = 65/180 (36%), Positives = 88/180 (48%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
NT GS+RC C PG++ P +EC + C C N G Y C C GY
Sbjct: 1131 NTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTP 1190
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPS 356
D C D+DEC C+ C+N+EGSYECSC+ G+ D +C DI+EC +
Sbjct: 1191 DRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICD 1250
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC-QAPCRNYAGGYRCDCPVG 530
G+C N+ G +RC+C G+ + CVD +EC C C N G + C C +G
Sbjct: 1251 GGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMG 1310
Score = 130 bits (313), Expect = 4e-30
Identities = 65/155 (41%), Positives = 80/155 (51%), Gaps = 7/155 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGV-RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
N IG F C C G+ P +ECA P C C NT GSY+C C GY L ED
Sbjct: 2183 NVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDR 2242
Query: 189 ANCRDVDECERDTHTC---QQICSNTEGSYECSCEDGYEKR--GDACVDINECH-EEGVC 350
C+D DECE H C Q C N G+Y C C GY++R G+ CVD NEC + G+C
Sbjct: 2243 RMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGIC 2302
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE 455
+ GRC+N GS+ C C G+ C+D E
Sbjct: 2303 EN-GRCLNTRGSYTCECNDGFTASPNQDECLDNRE 2336
Score = 127 bits (307), Expect = 2e-29
Identities = 67/182 (36%), Positives = 90/182 (49%), Gaps = 11/182 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD 179
+N GS+ C C GY+ RD EC C+ C NTDGS+ C+C G+ +
Sbjct: 505 INNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVT 564
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCP 353
DG NC D+DEC +C N +GS++C C+ G++ D C DINEC G+C
Sbjct: 565 RDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICM 624
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVD---RDEC---AQTGRCQAPCRNYAGGYRC 515
+ GRCVN GS+RC C G + +G CVD R C + G+C P C
Sbjct: 625 N-GRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSEC 683
Query: 516 DC 521
C
Sbjct: 684 CC 685
Score = 126 bits (304), Expect = 5e-29
Identities = 72/188 (38%), Positives = 89/188 (47%), Gaps = 10/188 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA---GRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYEL 176
VNT G F C C GY + DEC P C +CHNT+GSY C C G++L
Sbjct: 1087 VNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQL 1146
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECH-EEG 344
+ + C D++ECE H C C N G Y+C+C GY D CVDI+EC G
Sbjct: 1147 SPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNG 1206
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQ-APCRNYAGGYRCD 518
C + C N GS+ C C G+ L + C D DEC C C N G YRC
Sbjct: 1207 GCET--FCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCL 1264
Query: 519 CPVGTVRS 542
C G + S
Sbjct: 1265 CYDGFMAS 1272
Score = 126 bits (304), Expect = 5e-29
Identities = 68/179 (37%), Positives = 88/179 (49%), Gaps = 9/179 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA-GRGVRGRDECAV-RPPPC-DQLCHNTDGSYDCLCRTGYELDE 182
NTIGSF C C G+ + DECA C + C NT GS+ C C GYE+
Sbjct: 1907 NTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAP 1966
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSP 359
DG C D++EC + C C N +GSY C C GY + + C DI+EC EE +
Sbjct: 1967 DGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEICAL 2026
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVD--RDEC---AQTGRCQAPCRNYAGGYRCDC 521
G C N GSF+C+CP G+ L + G RC D C + G+C +P C C
Sbjct: 2027 GTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCC 2085
Score = 122 bits (294), Expect = 8e-28
Identities = 65/173 (37%), Positives = 91/173 (52%), Gaps = 7/173 (4%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C G G+ G + DEC V C + C N GSY C+C+TGY D G +C D++
Sbjct: 2390 CPHGRGFMTNGADI---DECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLN 2446
Query: 210 ECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINEC-HEEGVCPSPGRCVNLL 380
EC + C IC NTEGSY+CSC GY ++ G +C D++EC ++ C CVN +
Sbjct: 2447 ECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQF--LCVNTI 2504
Query: 381 GSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC--QAPCRNYAGGYRCDCPVG 530
G F C CP G+ C+D +EC + C + C+N G + C+C G
Sbjct: 2505 GGFTCKCPPGF--TQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRG 2555
Score = 122 bits (293), Expect = 1e-27
Identities = 60/161 (37%), Positives = 84/161 (52%), Gaps = 7/161 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNT 257
+EC + P C C NT GS+ C C +G+ LD + NC D+DEC C + C NT
Sbjct: 1030 NECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNT 1089
Query: 258 EGSYECSCEDGYEK---RGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAE 428
G +EC C++GYE C+DI+EC + + G C N GS+RC CP G++L
Sbjct: 1090 PGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPN 1149
Query: 429 GARCVDRDECAQTGR-C-QAPCRNYAGGYRCDCPVGTVRSP 545
+ C+D +EC + C C N G Y+C C G +P
Sbjct: 1150 ISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTP 1190
Score = 117 bits (282), Expect = 2e-26
Identities = 72/191 (37%), Positives = 93/191 (48%), Gaps = 10/191 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPG--YRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYEL 176
+N +GSFRC C G Y DEC P C + C NT GSY C C+ GY
Sbjct: 1783 INMVGSFRCECPVGFFYNDKLLVCEDIDECQ-NGPVCQRNAECINTAGSYRCDCKPGYRF 1841
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGV 347
G C D +EC+ + C C +T GS+ C C G++ D C+DINEC E
Sbjct: 1842 TSTG-QCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINEC-ERDA 1899
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGR-CQ-APCRNYAGGYRCD 518
C + G C N +GSF C C G+ L + C+D DECA G C+ C N G ++C
Sbjct: 1900 CGN-GTCRNTIGSFNCRCNHGFIL-SHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQ 1957
Query: 519 CPVGTVRSPSG 551
C G +P G
Sbjct: 1958 CNEGYEVAPDG 1968
Score = 116 bits (279), Expect = 6e-26
Identities = 61/163 (37%), Positives = 76/163 (46%), Gaps = 3/163 (1%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDG 188
NT+GS+RC+C GY G DEC+ C C N G Y C C G+ DG
Sbjct: 1382 NTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADG 1441
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPSPG 362
C D+DEC C N G + C CE GYE + G C D+NEC + C S G
Sbjct: 1442 KACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCIS-G 1500
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCR 491
CVN GS+ C CP + L+ CVD ++G C R
Sbjct: 1501 NCVNTPGSYICDCPPDFELNPTRVGCVD----TRSGNCYLDIR 1539
Score = 116 bits (279), Expect = 6e-26
Identities = 67/162 (41%), Positives = 78/162 (48%), Gaps = 6/162 (3%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTE 260
DEC P C C NTDGSY C C GY L G C D DEC C N
Sbjct: 2129 DECK-EPDVCKHGQCINTDGSYRCECPFGYILA--GNECVDTDECSVGNPCGNGTCKNVI 2185
Query: 261 GSYECSCEDGYEKRGD-ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGAR 437
G +EC+CE+G+E C DINEC + + + RCVN GS+ C CP GY L +
Sbjct: 2186 GGFECTCEEGFEPGPMMTCEDINECAQNPLLCA-FRCVNTYGSYECKCPVGYVLREDRRM 2244
Query: 438 CVDRDECAQTGR-C---QAPCRNYAGGYRCDCPVGTVRSPSG 551
C D DEC + C Q C+N G Y C C G R P G
Sbjct: 2245 CKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDG 2286
Score = 113 bits (273), Expect = 3e-25
Identities = 57/158 (36%), Positives = 82/158 (51%), Gaps = 5/158 (3%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQI--CSN 254
DEC P C+ +C N GS+ C C G+ ++ C D+DEC+ CQ+ C N
Sbjct: 1768 DECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGP-VCQRNAECIN 1826
Query: 255 TEGSYECSCEDGYEKRGDA-CVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAE 428
T GSY C C+ GY C D NEC E +C S G+C++ +GSF C+C G++ + +
Sbjct: 1827 TAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNIC-SHGQCIDTVGSFYCLCHTGFKTNDD 1885
Query: 429 GARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVRS 542
C+D +EC + CRN G + C C G + S
Sbjct: 1886 QTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILS 1923
Score = 113 bits (272), Expect = 4e-25
Identities = 56/139 (40%), Positives = 73/139 (52%), Gaps = 3/139 (2%)
Frame = +3
Query: 123 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 302
C T GS C C G++LD G C DVDECE++ + C N +GSY C C GY+
Sbjct: 465 CIPTPGSCRCECNKGFQLDLRG-ECIDVDECEKNPCAGGE-CINNQGSYTCQCRAGYQST 522
Query: 303 --GDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC 476
C DI+EC + G + GRC+N GSF CVC G+ + +G C D DEC+ C
Sbjct: 523 LTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMC 582
Query: 477 -QAPCRNYAGGYRCDCPVG 530
C N G ++C C G
Sbjct: 583 LNGMCINEDGSFKCICKPG 601
Score = 112 bits (270), Expect = 7e-25
Identities = 72/215 (33%), Positives = 93/215 (43%), Gaps = 35/215 (16%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
N IG++ C+CGPGY RP G G +EC +P C+ C NT GSY C C G+
Sbjct: 2267 NLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASP 2326
Query: 183 DGANCRDVDECERDTHTCQQICS------NTEGSYECSCED--GYEKRGDAC-------- 314
+ C D E T Q +C N EC C+ G+ + C
Sbjct: 2327 NQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAF 2386
Query: 315 --------------VDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR 449
DI+EC VC + G CVN GS+ C+C GY D G CVD
Sbjct: 2387 KKLCPHGRGFMTNGADIDECKVIHDVCRN-GECVNDRGSYHCICKTGYTPDITGTSCVDL 2445
Query: 450 DECAQTGR-CQAPCRNYAGGYRCDCPVGTVRSPSG 551
+EC Q + C C+N G Y+C CP G + G
Sbjct: 2446 NECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDG 2480
Score = 109 bits (261), Expect = 8e-24
Identities = 61/158 (38%), Positives = 83/158 (52%), Gaps = 9/158 (5%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C GPG AG + +ECA+ P C +C N G+Y C+C +GYE+D G NC D++
Sbjct: 711 CSSGPGMTSAGSDI---NECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDIN 767
Query: 210 ECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLL 380
EC ++ C C NT GS+ C+C G+ + D C DI+EC E C + G C N
Sbjct: 768 ECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDEC-ESSPCIN-GVCKNSP 825
Query: 381 GSFRCVCPRGYRLDAEGARCVD--RDECAQT---GRCQ 479
GSF C C LD C++ + C QT GRC+
Sbjct: 826 GSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCE 863
Score = 103 bits (248), Expect = 3e-22
Identities = 51/150 (34%), Positives = 69/150 (46%), Gaps = 3/150 (2%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCE 284
PC Y LC +G + G+ D++EC D C IC N G+Y+C C
Sbjct: 695 PCQPCPAQNSAEYQALCSSGPGMTSAGS---DINECALDPDICPNGICENLRGTYKCICN 751
Query: 285 DGYE--KRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC 458
GYE G CVDINEC + G+C N GSF C CP+G+ + C D DEC
Sbjct: 752 SGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDEC 811
Query: 459 AQTGRCQAPCRNYAGGYRCDCPVGTVRSPS 548
+ C+N G + C+C + P+
Sbjct: 812 ESSPCINGVCKNSPGSFICECSSESTLDPT 841
Score = 96.7 bits (230), Expect = 5e-20
Identities = 44/110 (40%), Positives = 60/110 (54%), Gaps = 4/110 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
R +NT GSF CVC G+ G+ DEC++R + +C N DGS+ C+C+ G++L
Sbjct: 545 RCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQL 604
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVD 320
DG C+D++ECE C NT+GSY C C G G CVD
Sbjct: 605 ASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVD 654
Score = 94.7 bits (225), Expect = 2e-19
Identities = 53/147 (36%), Positives = 69/147 (46%), Gaps = 4/147 (2%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCRTGYEL---DEDGANCRDVDECERDTHTCQQICSNTEGSYECS 278
PC+ D ++ +C G + +D A D+DEC+ C NT+GSY C
Sbjct: 2095 PCELCPTEPDEAFRQICPYGSGIIVGPDDSAV--DMDECKEPDVCKHGQCINTDGSYRCE 2152
Query: 279 CEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC 458
C GY G+ CVD +EC C + G C N++G F C C G+ C D +EC
Sbjct: 2153 CPFGYILAGNECVDTDECSVGNPCGN-GTCKNVIGGFECTCEEGFE-PGPMMTCEDINEC 2210
Query: 459 AQTG-RCQAPCRNYAGGYRCDCPVGTV 536
AQ C C N G Y C CPVG V
Sbjct: 2211 AQNPLLCAFRCVNTYGSYECKCPVGYV 2237
Score = 89.0 bits (211), Expect = 1e-17
Identities = 68/216 (31%), Positives = 89/216 (41%), Gaps = 42/216 (19%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+N G +RC C G+ P+ G+ DEC++ CHN G + C C GYELD
Sbjct: 1421 LNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDR 1480
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE-----------KRGDACVDI-- 323
G NC DV+EC T C NT GSY C C +E + G+ +DI
Sbjct: 1481 SGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRP 1540
Query: 324 ------NECHEE-GVCPSPGRCVNLLG----------------SFRCVCP--RGYRLDAE 428
C E GV S C LG ++ +CP G+R +
Sbjct: 1541 RGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPI 1600
Query: 429 GARCVDRDECAQ-TGRCQ-APCRNYAGGYRCDCPVG 530
D DEC + G CQ C N G ++C CP G
Sbjct: 1601 TVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTG 1636
Score = 87.4 bits (207), Expect = 3e-17
Identities = 57/179 (31%), Positives = 79/179 (44%), Gaps = 7/179 (3%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVR-PPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C C G A G +EC +R P ++LC G E+ +D++
Sbjct: 980 CCCSVG---AAWGTEECEECPMRNTPEYEELCPRGPGF------ATKEITNGKPFFKDIN 1030
Query: 210 ECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLL 380
EC+ C C NT GS++C C+ G+ + C DI+EC G+CVN
Sbjct: 1031 ECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTP 1090
Query: 381 GSFRCVCPRGYRLDAEGAR-CVDRDECAQTGR-CQAP-CRNYAGGYRCDCPVGTVRSPS 548
G F C C GY + C+D DEC + C+ C N G YRC+CP G SP+
Sbjct: 1091 GDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPN 1149
Score = 85.0 bits (201), Expect = 2e-16
Identities = 61/209 (29%), Positives = 91/209 (43%), Gaps = 29/209 (13%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
N G+++C+C GY G+ +EC + CD C NT GS+ C C G+
Sbjct: 741 NLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKP 800
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSY--ECSCEDGYEKRGDACVDI--NECHE---E 341
D C D+DECE + +C N+ GS+ ECS E + C++ C + +
Sbjct: 801 DLKTCEDIDECE-SSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVID 859
Query: 342 GVC-------PSPGRCVNLLGS---FRC-------VCPRGYRLDAEGARCVDRDEC-AQT 467
G C +C + LG+ C +C +GY +G +C D DEC
Sbjct: 860 GRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYS-RIKGTQCEDIDECEVFP 918
Query: 468 GRCQ-APCRNYAGGYRCDCPVGTVRSPSG 551
G C+ C N G ++C CP G +G
Sbjct: 919 GVCKNGLCVNTRGSFKCQCPSGMTLDATG 947
Score = 84.6 bits (200), Expect = 2e-16
Identities = 52/149 (34%), Positives = 65/149 (43%), Gaps = 13/149 (8%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQL---CHNTDGSYDCLCRTG 167
R VNT GS+ C C GY R R + DEC C + C N G+Y C+C G
Sbjct: 2220 RCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPG 2279
Query: 168 YELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGY--EKRGDACVDINE--C 332
Y+ DG C D +EC+ C+ C NT GSY C C DG+ D C+D E C
Sbjct: 2280 YQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYC 2339
Query: 333 HEE---GVCPSPGRCVNLLGSFRCVCPRG 410
E +C N + C C G
Sbjct: 2340 FTEVLQNMCQIGSSNRNPVTKSECCCDGG 2368
Score = 83.4 bits (197), Expect = 5e-16
Identities = 49/139 (35%), Positives = 64/139 (46%), Gaps = 9/139 (6%)
Frame = +3
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKR--GDACVDIN 326
CR G+ + C+DVDEC+ CQ C NT GS+EC C G++ C DI+
Sbjct: 231 CRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDID 290
Query: 327 ECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD-RDECAQT----GRCQAPC 488
EC G+C G C N + S+ C CP G+ +G RC+D R T GRC
Sbjct: 291 ECSTIPGICEG-GECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQL 349
Query: 489 RNYAGGYRCDCPVGTVRSP 545
+C C G SP
Sbjct: 350 PQSITKMQCCCDAGRCWSP 368
Score = 80.6 bits (190), Expect = 3e-15
Identities = 41/118 (34%), Positives = 55/118 (46%), Gaps = 5/118 (4%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCR--TGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECS 278
PC+ Y LC G+ + D+DEC+ CQ C NT GS++C
Sbjct: 1573 PCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCR 1632
Query: 279 CEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
C GY D C D+NEC G+C PG C N +G++ C+CP Y G C+D
Sbjct: 1633 CPTGYYLNEDTRVCDDVNECETPGIC-GPGTCYNTVGNYTCICPPDYMQVNGGNNCMD 1689
Score = 77.4 bits (182), Expect = 3e-14
Identities = 57/183 (31%), Positives = 78/183 (42%), Gaps = 10/183 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDE----CAVRPPPCDQLCHNT--DGSYDCLCRTGYE 173
NT+G++ C+C P Y G D C +Q C +C Y
Sbjct: 1665 NTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYN 1724
Query: 174 LDEDGANCRDVDECE-RDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHE-EGV 347
+ A + ++C T +C + + G VDI+EC E GV
Sbjct: 1725 IGR--AWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLP------VDIDECREIPGV 1776
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ--APCRNYAGGYRCDC 521
C + G C+N++GSFRC CP G+ + + C D DEC CQ A C N AG YRCDC
Sbjct: 1777 CEN-GVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDC 1835
Query: 522 PVG 530
G
Sbjct: 1836 KPG 1838
Score = 77.0 bits (181), Expect = 4e-14
Identities = 60/173 (34%), Positives = 81/173 (46%), Gaps = 28/173 (16%)
Frame = +3
Query: 12 NTIGSFRCVCGPG--YRPAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDE 182
NT GSF C C G Y+P + DEC PC + +C N+ GS+ C C + LD
Sbjct: 783 NTPGSFVCTCPKGFIYKPDLKTCEDIDEC--ESSPCINGVCKNSPGSFICECSSESTLDP 840
Query: 183 DGANCRD----------VD-ECERDTHTC---QQICSNTEGSY--ECS-------CEDGY 293
C + +D CE + + Q CS+ ++ C+ C GY
Sbjct: 841 TKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGY 900
Query: 294 EK-RGDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
+ +G C DI+EC GVC + G CVN GSF+C CP G LDA G C+D
Sbjct: 901 SRIKGTQCEDIDECEVFPGVCKN-GLCVNTRGSFKCQCPSGMTLDATGRICLD 952
Score = 76.6 bits (180), Expect = 5e-14
Identities = 36/87 (41%), Positives = 47/87 (54%), Gaps = 3/87 (3%)
Frame = +3
Query: 300 RGDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGR 473
R AC D++EC G+C G C+N +GSF C CP G++L+ +C D DEC+ G
Sbjct: 240 RTGACQDVDECQAIPGLCQG-GNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGI 298
Query: 474 CQ-APCRNYAGGYRCDCPVGTVRSPSG 551
C+ C N Y C CP G SP G
Sbjct: 299 CEGGECTNTVSSYFCKCPPGFYTSPDG 325
Score = 76.6 bits (180), Expect = 5e-14
Identities = 39/105 (37%), Positives = 51/105 (48%), Gaps = 3/105 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDE--CAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
N IG +RC C GY + + DE C CHNT GSY C+C G++ ++
Sbjct: 2583 NIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQF 2642
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CV 317
C+D++EC C SNTEG Y C C GY + G CV
Sbjct: 2643 SGGCQDINECGSAQAPCSYGSSNTEGGYLCGCPPGYFRIGQGHCV 2687
Score = 71.7 bits (168), Expect = 2e-12
Identities = 53/178 (29%), Positives = 72/178 (40%), Gaps = 6/178 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDE 182
VNT GS+ C C P + V D R C D +G C G + +
Sbjct: 1503 VNTPGSYICDCPPDFELNPTRVGCVD---TRSGNCYLDIRPRGDNGDTACSNEIGVGVSK 1559
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV--DINECHE-EGVCP 353
C C + + +E C +G+ + DI+EC E G+C
Sbjct: 1560 ASCCCSLGKAWGTPCEMCPAV-NTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQ 1618
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCP 524
G+C+N GSF+C CP GY L+ + C D +EC G C C N G Y C CP
Sbjct: 1619 G-GKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICP 1675
Score = 70.1 bits (164), Expect = 5e-12
Identities = 44/112 (39%), Positives = 56/112 (50%), Gaps = 7/112 (6%)
Frame = +3
Query: 9 VNTIGSFRCVC--GPGYRPAGRGV--RGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYE 173
VNT ++ +C G G+RP V DEC P C C NT GS+ C C TGY
Sbjct: 1580 VNT-SEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYY 1638
Query: 174 LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK--RGDACVDI 323
L+ED C DV+ECE C NT G+Y C C Y + G+ C+D+
Sbjct: 1639 LNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDM 1690
Score = 69.3 bits (162), Expect = 8e-12
Identities = 41/119 (34%), Positives = 55/119 (46%), Gaps = 10/119 (8%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ-QICSNT 257
DEC P C C NT GS++C C G++L+E C D+DEC C+ C+NT
Sbjct: 248 DECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNT 307
Query: 258 EGSYECSCEDGY--EKRGDACVDINE--CHEEGVCPSPGRCVNLL----GSFRCVCPRG 410
SY C C G+ G C+D+ C+ + GRC N L +C C G
Sbjct: 308 VSSYFCKCPPGFYTSPDGTRCIDVRPGYCY---TALTNGRCSNQLPQSITKMQCCCDAG 363
Score = 63.3 bits (147), Expect = 5e-10
Identities = 54/184 (29%), Positives = 74/184 (40%), Gaps = 10/184 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGR---GVRGRDECAVR--PPPCDQLCHNTDGSYDCLCRTG 167
VNT GSF+C C G GR +R + C +R C C C G
Sbjct: 927 VNTRGSFKCQCPSGMTLDATGRICLDIR-LETCFLRYEDEECTLPIAGRHRMDACCCSVG 985
Query: 168 YELDEDGANCRDVDECE-RDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEG 344
+ + +EC R+T +++C G +G DINEC
Sbjct: 986 AAWGTE-----ECEECPMRNTPEYEELCPRGPGFATKEITNG----KPFFKDINECKMIP 1036
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC-QAPCRNYAGGYRCD 518
+ G+C N +GSF+C C G+ LD+E C D DEC C + C N G + C
Sbjct: 1037 SLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECK 1096
Query: 519 CPVG 530
C G
Sbjct: 1097 CDEG 1100
Score = 56.4 bits (130), Expect = 6e-08
Identities = 24/57 (42%), Positives = 30/57 (52%)
Frame = +3
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
GRC+ GS RC C +G++LD G C+D DEC + C N G Y C C G
Sbjct: 463 GRCIPTPGSCRCECNKGFQLDLRG-ECIDVDECEKNPCAGGECINNQGSYTCQCRAG 518
Score = 55.6 bits (128), Expect = 1e-07
Identities = 40/135 (29%), Positives = 51/135 (37%), Gaps = 4/135 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCD-QLCHNTDGSYDCLCRTGYELD 179
+NT+GSF C C G++ + DEC+ P C+ C NT SY C C G+
Sbjct: 263 INTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTS 322
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSP 359
DG C DV T CSN K C D C GV +P
Sbjct: 323 PDGTRCIDVRPGYCYTALTNGRCSN-------QLPQSITKM-QCCCDAGRCWSPGVTVAP 374
Query: 360 GRC-VNLLGSFRCVC 401
C + F +C
Sbjct: 375 EMCPIRATEDFNKLC 389
Score = 54.8 bits (126), Expect = 2e-07
Identities = 52/178 (29%), Positives = 66/178 (37%), Gaps = 13/178 (7%)
Frame = +3
Query: 36 VCGPGY-RPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDV- 206
+CG GY R G DEC V P C LC NT GS+ C C +G LD G C D+
Sbjct: 895 ICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIR 954
Query: 207 -DEC--ERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNL 377
+ C + C + C C G A EC E CP +
Sbjct: 955 LETCFLRYEDEECTLPIAGRHRMDACCCSVG------AAWGTEECEE---CP-----MRN 1000
Query: 378 LGSFRCVCPRGYRLDAEGAR-----CVDRDECAQ-TGRC-QAPCRNYAGGYRCDCPVG 530
+ +CPRG + D +EC C CRN G ++C C G
Sbjct: 1001 TPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSG 1058
Score = 33.9 bits (74), Expect = 0.38
Identities = 40/144 (27%), Positives = 56/144 (38%), Gaps = 6/144 (4%)
Frame = +3
Query: 3 RGVNTIGS-FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYD--CLCRTGYE 173
+G N GS + C PG++ + G ++C V P C C + S C C +G
Sbjct: 54 KGPNVCGSRYNAYCCPGWKT----LPGGNQCIV--PICRHSCGDGFCSRPNMCTCPSGQI 107
Query: 174 LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC---VDINECHEEG 344
G+ R + C C S ++ C C+ GY G C V + C G
Sbjct: 108 APSCGS--RSIQHCNI---RCMNGGSCSDD--HCLCQKGYI--GTHCGQPVCESGCLNGG 158
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYR 416
C +P RC G C R YR
Sbjct: 159 RCVAPNRCACTYGFTGPQCERDYR 182
>AY165865-1|AAO18147.1| 2809|Homo sapiens fibrillin-3 short form
precursor transcript variant 3 protein.
Length = 2809
Score = 184 bits (447), Expect = 2e-46
Identities = 81/177 (45%), Positives = 102/177 (57%), Gaps = 3/177 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+N++GSFRC C GY P DEC+ P PC LC NT GS+ C C GY L+E
Sbjct: 2380 INSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEE 2439
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECH-EEGVCPSP 359
DG C+D+DEC H CQ +C NT G++ C C G+ + AC D +EC + G C +
Sbjct: 2440 DGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAH 2499
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
G C N GSFRC C +G+ L + G C D +EC RCQ C+N GGYRC CP G
Sbjct: 2500 GHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGGYRCSCPQG 2556
Score = 163 bits (397), Expect = 3e-40
Identities = 78/186 (41%), Positives = 94/186 (50%), Gaps = 5/186 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELDE 182
VNT+G+F C C PG+ + DEC+ +P PC CHNT GS+ C C G+ L
Sbjct: 2462 VNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVS 2521
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPS 356
G C DV+EC+ H CQ C N G Y CSC G+ + CVD NEC
Sbjct: 2522 SGHGCEDVNECD-GPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCG 2580
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRCDCPVGT 533
C N LG FRCVCP G+ D C D DECA + G C C N GG+ C CP G
Sbjct: 2581 SASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGY 2640
Query: 534 VRSPSG 551
R+ G
Sbjct: 2641 FRAGQG 2646
Score = 161 bits (390), Expect = 2e-39
Identities = 82/189 (43%), Positives = 105/189 (55%), Gaps = 9/189 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
NT+GSF C C G+ R DEC + P C Q C NT GS++C C GYE
Sbjct: 1004 NTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGF 1063
Query: 183 D-GANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYE--KRGDACVDINECH-EEGV 347
NC DVDEC RD C+ C+NT+GSY+C C G+E +G AC DI+EC +G+
Sbjct: 1064 MLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGL 1123
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQAPCRNYAGGYRCDCP 524
CP G+CVN++G+F+C C G++ + CVD +EC Q G C C N G YRC C
Sbjct: 1124 CPH-GQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCG 1182
Query: 525 VGTVRSPSG 551
G P G
Sbjct: 1183 QGYSLMPDG 1191
Score = 150 bits (364), Expect = 3e-36
Identities = 81/189 (42%), Positives = 98/189 (51%), Gaps = 10/189 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA---GRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYEL 176
VNT GSF C C PGY + DECA P C C NTDGSY C C G+EL
Sbjct: 1045 VNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHEL 1104
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECH-EEG 344
G C D+DEC C C N G+++CSC G++ D CVDINEC + G
Sbjct: 1105 TAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNG 1164
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-C-QAPCRNYAGGYRCD 518
C C+N GS+RC C +GY L +G C D DEC + R C Q C N GG+RC
Sbjct: 1165 GCDV--HCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCL 1222
Query: 519 CPVGTVRSP 545
C G + +P
Sbjct: 1223 CYDGFMATP 1231
Score = 141 bits (342), Expect = 1e-33
Identities = 75/187 (40%), Positives = 90/187 (48%), Gaps = 6/187 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELDE 182
+N GSF C C PG+ G DEC + C C N GSY C CR G+
Sbjct: 1298 LNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFA--G 1355
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCP 353
DG C D DEC + C C N G Y C CE G++ D AC D++EC + +C
Sbjct: 1356 DGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLC- 1414
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPVG 530
+ G C NL G FRC+C GY LD G C D +ECA C C N G Y C CP
Sbjct: 1415 AFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQD 1474
Query: 531 TVRSPSG 551
+PSG
Sbjct: 1475 FELNPSG 1481
Score = 140 bits (340), Expect = 2e-33
Identities = 80/189 (42%), Positives = 98/189 (51%), Gaps = 9/189 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VNT GSFRC C GY G+ DEC+V P C N G ++C C G+E
Sbjct: 2101 VNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGL 2160
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINECHE-EGVCP 353
C D+DEC + C C NTEGSY C+C GY R D C D++EC + + C
Sbjct: 2161 M-MTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCH 2219
Query: 354 SPG-RCVNLLGSFRCVCPRGYR-LDAEGARCVDRDEC-AQTGRC-QAPCRNYAGGYRCDC 521
+ G C NL+G+F CVCP G R L G C D +EC AQ C C N AG +RCDC
Sbjct: 2220 ARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDC 2279
Query: 522 PVGTVRSPS 548
G SP+
Sbjct: 2280 DEGFQPSPT 2288
Score = 138 bits (335), Expect = 9e-33
Identities = 75/184 (40%), Positives = 91/184 (49%), Gaps = 8/184 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN IG+F+C C G++ P +G +EC V+ CD C NT+GSY C C GY L
Sbjct: 1130 VNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMP 1189
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCP 353
DG C DVDECE + C Q C+N G + C C DG+ D CVD++EC
Sbjct: 1190 DGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHIC 1249
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG-RC--QAPCRNYAGGYRCDCP 524
G C N GSF C C GY + C D DEC G C A C N G + C C
Sbjct: 1250 LHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCL 1309
Query: 525 VGTV 536
G V
Sbjct: 1310 PGWV 1313
Score = 132 bits (320), Expect = 6e-31
Identities = 65/152 (42%), Positives = 77/152 (50%), Gaps = 7/152 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA-GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
N IG F C C G+ P DEC++ P C CHNT+GSY C C GY L EDG
Sbjct: 2143 NVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDG 2202
Query: 189 ANCRDVDEC---ERDTHTCQQICSNTEGSYECSCEDGYEK---RGDACVDINECHEEGVC 350
A CRDVDEC ++D H C N G++ C C G G+ C D NECH +
Sbjct: 2203 AMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDL 2262
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
GRCVN GSFRC C G++ C D
Sbjct: 2263 CVNGRCVNTAGSFRCDCDEGFQPSPTLTECHD 2294
Score = 132 bits (319), Expect = 8e-31
Identities = 75/190 (39%), Positives = 104/190 (54%), Gaps = 9/190 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGV--RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
++T GS+ C+C G++ + DEC R P + C N GSY+CLC G+ +
Sbjct: 1822 MDTEGSYMCLCHRGFQASADQTLCMDIDECD-RQPCGNGTCKNIIGSYNCLCFPGFVVTH 1880
Query: 183 DGANCRDVDECERDT-HTCQ-QICSNTEGSYECSCEDGYEKRGDA--CVDINECHE-EGV 347
+G +C D DEC C+ C NT GS+ C C+DG+E D CVD NEC G
Sbjct: 1881 NG-DCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGT 1939
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQ-APCRNYAGGYRCDC 521
C PG C NL GSFRC+CP G+++ ++ C+D DEC++ C C N G ++C C
Sbjct: 1940 C-LPGTCQNLEGSFRCICPPGFQVQSD--HCIDIDECSEEPNLCLFGTCTNSPGSFQCLC 1996
Query: 522 PVGTVRSPSG 551
P G V S +G
Sbjct: 1997 PPGFVLSDNG 2006
Score = 132 bits (318), Expect = 1e-30
Identities = 65/180 (36%), Positives = 85/180 (47%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
NT GS++C C PG+ +G D EC++ C C N G++ C C G++
Sbjct: 1089 NTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTP 1148
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPS 356
D C D++EC C C NTEGSY CSC GY G AC D++EC E
Sbjct: 1149 DRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCD 1208
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-C-QAPCRNYAGGYRCDCPVG 530
G C N+ G RC+C G+ + CVD DEC C C N G + C C +G
Sbjct: 1209 QGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLG 1268
Score = 131 bits (316), Expect = 2e-30
Identities = 70/179 (39%), Positives = 90/179 (50%), Gaps = 9/179 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRG-VRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELDE 182
N IGS+ C+C PG+ G DEC + C NT GS+ CLC+ G+EL
Sbjct: 1863 NIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTA 1922
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSP 359
DG NC D +EC TC C N EGS+ C C G++ + D C+DI+EC EE
Sbjct: 1923 DGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDIDECSEEPNLCLF 1982
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE--C---AQTGRCQAPCRNYAGGYRCDC 521
G C N GSF+C+CP G+ L G RC D + C + G+C P RC C
Sbjct: 1983 GTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCC 2041
Score = 130 bits (314), Expect = 3e-30
Identities = 64/161 (39%), Positives = 82/161 (50%), Gaps = 7/161 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNT 257
+EC V P C C NT GS+ C C G+ LD NC D+DEC C Q C NT
Sbjct: 988 NECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNT 1047
Query: 258 EGSYECSCEDGYEKRG---DACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAE 428
GS+EC C GYE C+D++EC + + G C N GS++C CP G+ L A+
Sbjct: 1048 PGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAK 1107
Query: 429 GARCVDRDECA-QTGRC-QAPCRNYAGGYRCDCPVGTVRSP 545
G C D DEC+ G C C N G ++C C G +P
Sbjct: 1108 GTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTP 1148
Score = 127 bits (307), Expect = 2e-29
Identities = 69/156 (44%), Positives = 83/156 (53%), Gaps = 7/156 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNT 257
+ECA P C +C NTDGS+ C C GY LD G NC D DEC H C Q C+N
Sbjct: 2086 NECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVG-HPCGQGTCTNV 2144
Query: 258 EGSYECSCEDGYEK-RGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGA 434
G +EC+C DG+E C DI+EC + RC N GS+ C CP GY L +GA
Sbjct: 2145 IGGFECACADGFEPGLMMTCEDIDECSLNPLL-CAFRCHNTEGSYLCTCPAGYTLREDGA 2203
Query: 435 RCVDRDECAQTGR-CQA---PCRNYAGGYRCDCPVG 530
C D DECA + C A C+N G + C CP G
Sbjct: 2204 MCRDVDECADGQQDCHARGMECKNLIGTFACVCPPG 2239
Score = 126 bits (305), Expect = 4e-29
Identities = 67/182 (36%), Positives = 89/182 (48%), Gaps = 11/182 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD 179
VN G++ C C PG++ P + DEC V C C NT+GS+ C+C G+EL
Sbjct: 464 VNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELS 523
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINECHEEGVCP 353
DG NC D +EC T +C N +GS+ C C+ G+ G C+DI+EC G+C
Sbjct: 524 PDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICV 583
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVD---RDEC---AQTGRCQAPCRNYAGGYRC 515
+ G C N GSFRC C G + +G CVD R C + G C P C
Sbjct: 584 N-GHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSEC 642
Query: 516 DC 521
C
Sbjct: 643 CC 644
Score = 126 bits (304), Expect = 5e-29
Identities = 70/180 (38%), Positives = 82/180 (45%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELD 179
NT GSF C C GY R G DEC V CD C N GS+ C C G+
Sbjct: 1256 NTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWV-- 1313
Query: 180 EDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCP 353
DG C D+DEC H C C N GSY C+C G+ G C D +EC E
Sbjct: 1314 GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLC 1373
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ-APCRNYAGGYRCDCPVG 530
G+C+N G +RC C G+ + C D DECAQ C C N G +RC C G
Sbjct: 1374 DNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMFRCICNGG 1433
Score = 123 bits (297), Expect = 4e-28
Identities = 71/180 (39%), Positives = 90/180 (50%), Gaps = 7/180 (3%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C G GY GR V DEC + C C N+ GS+ C C+ GY D C D+D
Sbjct: 2351 CPHGSGYTAEGRDV---DECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMD 2407
Query: 210 ECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINEC-HEEGVCPSPGRCVNLL 380
EC + C +C NT+GS+ CSC GY E+ G C D++EC + C CVN +
Sbjct: 2408 ECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQF--LCVNTV 2465
Query: 381 GSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQA--PCRNYAGGYRCDCPVGTVRSPSG 551
G+F C CP G+ + C D DEC AQ G C A C N G +RC+C G SG
Sbjct: 2466 GAFTCRCPPGFTQHHQA--CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSG 2523
Score = 122 bits (295), Expect = 6e-28
Identities = 73/189 (38%), Positives = 88/189 (46%), Gaps = 6/189 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRG-VRGRDECAVRPPPCDQL-CHNTDGSYDCLCRTGYEL 176
R + T S+RC C GY RG DEC PC C N G+Y C C G++
Sbjct: 423 RCLPTPSSYRCECNVGYTQDVRGECIDVDECT--SSPCHHGDCVNIPGTYHCRCYPGFQA 480
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGV 347
C DVDEC C C NTEGS++C C G+E D CVD NEC +
Sbjct: 481 TPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTM 540
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCP 524
C + G C+N GSF C+C G+ L G C+D DEC G C C N G +RC C
Sbjct: 541 CVN-GVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCL 599
Query: 525 VGTVRSPSG 551
G G
Sbjct: 600 GGLAVGTDG 608
Score = 122 bits (294), Expect = 8e-28
Identities = 64/178 (35%), Positives = 83/178 (46%), Gaps = 4/178 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDED 185
+N GS+RC C G+ G RDECA CD C N G Y C C G++ ED
Sbjct: 1339 LNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTED 1398
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPSP 359
C+DVDEC + C N G + C C GYE + G C DINEC + C +
Sbjct: 1399 HRACQDVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCIN- 1457
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYA-GGYRCDCPVG 530
G C+N GS+ C CP+ + L+ G CVD + G C + G C +G
Sbjct: 1458 GVCINTPGSYLCSCPQDFELNPSGVGCVD----TRAGNCFLETHDRGDSGISCSAEIG 1511
Score = 122 bits (293), Expect = 1e-27
Identities = 73/184 (39%), Positives = 93/184 (50%), Gaps = 10/184 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPG--YRPAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYEL 176
+N IGSFRC C G Y DEC R PC Q C N GSY C C GY+L
Sbjct: 1738 INQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKL 1797
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGV 347
GA C +EC + C C +TEGSY C C G++ D C+DI+EC +
Sbjct: 1798 SPGGA-CVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQ-P 1855
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGR-CQ-APCRNYAGGYRCD 518
C + G C N++GS+ C+C G+ + G CVD DEC G+ C+ C N AG + C
Sbjct: 1856 CGN-GTCKNIIGSYNCLCFPGFVVTHNG-DCVDFDECTTLVGQVCRFGHCLNTAGSFHCL 1913
Query: 519 CPVG 530
C G
Sbjct: 1914 CQDG 1917
Score = 119 bits (286), Expect = 8e-27
Identities = 64/161 (39%), Positives = 82/161 (50%), Gaps = 5/161 (3%)
Frame = +3
Query: 84 DECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQI--CSN 254
DEC P C + +C N GS+ C C G+ + C DVDEC CQQ C N
Sbjct: 1723 DECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCIN 1782
Query: 255 TEGSYECSCEDGYE-KRGDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAE 428
GSY C C GY+ G ACV NEC E VC S G C++ GS+ C+C RG++ A+
Sbjct: 1783 IPGSYRCKCTRGYKLSPGGACVGRNECREIPNVC-SHGDCMDTEGSYMCLCHRGFQASAD 1841
Query: 429 GARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVRSPSG 551
C+D DEC + C+N G Y C C G V + +G
Sbjct: 1842 QTLCMDIDECDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNG 1882
Score = 109 bits (263), Expect = 5e-24
Identities = 65/175 (37%), Positives = 85/175 (48%), Gaps = 9/175 (5%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C G G GR + +ECA+ P C + +C N GSY C+C GYE G +C DVD
Sbjct: 670 CSSGLGITTDGRDI---NECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVD 726
Query: 210 ECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLL 380
EC ++ C C N+ GSY CSC G+ D C D++EC C S G C NL
Sbjct: 727 ECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP-CVS-GVCRNLA 784
Query: 381 GSFRCVCPRGYRLDAEGARCVD--RDEC---AQTGRCQAPCRNYAGGYRCDCPVG 530
GS+ C C G RLD G C+D + C Q RC+ + + C +G
Sbjct: 785 GSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLG 839
Score = 109 bits (262), Expect = 6e-24
Identities = 57/152 (37%), Positives = 71/152 (46%), Gaps = 4/152 (2%)
Frame = +3
Query: 108 PCDQLCH-NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSC 281
PC QLC + LC +G + DG RD++EC D C +C N GSY C C
Sbjct: 654 PC-QLCPAKNSAEFQALCSSGLGITTDG---RDINECALDPEVCANGVCENLRGSYRCVC 709
Query: 282 EDGYEK--RGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE 455
GYE G C D++EC + G C N GS+ C CP G+ + C D DE
Sbjct: 710 NLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDE 769
Query: 456 CAQTGRCQAPCRNYAGGYRCDCPVGTVRSPSG 551
C + CRN AG Y C C G+ PSG
Sbjct: 770 CLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSG 801
Score = 105 bits (251), Expect = 1e-22
Identities = 69/215 (32%), Positives = 96/215 (44%), Gaps = 35/215 (16%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRP---AGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELD 179
N IG+F CVC PG RP +G G +EC +P C + C NT GS+ C C G++
Sbjct: 2227 NLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPS 2286
Query: 180 EDGANCRDVDE--CERDT--HTCQQICSNTEG--SYECSCED--GYEKRGDACV------ 317
C D+ + C + C+ + S++E EC C G+ R + C
Sbjct: 2287 PTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSA 2346
Query: 318 ----------------DINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR 449
D++EC + G C+N LGSFRC C GY DA C+D
Sbjct: 2347 YRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDM 2406
Query: 450 DECAQTGR-CQAPCRNYAGGYRCDCPVGTVRSPSG 551
DEC+Q + C C+N G + C CP G + G
Sbjct: 2407 DECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDG 2441
Score = 99.1 bits (236), Expect = 9e-21
Identities = 72/219 (32%), Positives = 94/219 (42%), Gaps = 36/219 (16%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
R VNT GSF+CVC G+ P G+ +ECA + +C N DGS+ CLC+ G+ L
Sbjct: 504 RCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLL 563
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDI---NECH-- 335
G C D+DEC+ C+NTEGS+ C C G G CVD + C+
Sbjct: 564 APGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGA 623
Query: 336 -EEGVC--PSPGR-------CVN---------------LLGSFRCVCPRGYRLDAEGARC 440
E+G C P PG C N F+ +C G + +G
Sbjct: 624 IEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGR-- 681
Query: 441 VDRDECAQTGR--CQAPCRNYAGGYRCDCPVGTVRSPSG 551
D +ECA C N G YRC C +G SG
Sbjct: 682 -DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASG 719
Score = 97.5 bits (232), Expect = 3e-20
Identities = 71/209 (33%), Positives = 91/209 (43%), Gaps = 29/209 (13%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
N GS+RCVC GY +G+ DECA+ CD C N+ GSY C C G+ +
Sbjct: 700 NLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQ 759
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG--YEKRGDACVDINE--CH---EE 341
D C+DVDEC + +C N GSY C C G + G C+D + C +E
Sbjct: 760 DTEICKDVDEC-LSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQE 818
Query: 342 GVC-------PSPGRCVNLLGSF------RC----VCPRGYRLDAEGARCVDRDECAQ-T 467
C C LG+ RC C RG+ G C D +EC
Sbjct: 819 SRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGF-ARMTGVTCDDVNECESFP 877
Query: 468 GRC-QAPCRNYAGGYRCDCPVGTVRSPSG 551
G C C N AG +RC+CP G + SG
Sbjct: 878 GVCPNGRCVNTAGSFRCECPEGLMLDASG 906
Score = 88.2 bits (209), Expect = 2e-17
Identities = 73/207 (35%), Positives = 91/207 (43%), Gaps = 32/207 (15%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
N+ GS+ C C PG+ + DEC + P +C N GSY C C G LD
Sbjct: 742 NSPGSYSCSCPPGFHFWQDTEICKDVDEC-LSSPCVSGVCRNLAGSYTCKCGPGSRLDPS 800
Query: 186 GANCRD---------VDE--CERDTH--TCQQICSNTEGSY------EC----SCEDGYE 296
G C D + E CE + + + C T G+ C +C G+
Sbjct: 801 GTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFA 860
Query: 297 KR-GDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD-RDECAQT 467
+ G C D+NEC GVCP+ GRCVN GSFRC CP G LDA G CVD R E
Sbjct: 861 RMTGVTCDDVNECESFPGVCPN-GRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFL 919
Query: 468 GRCQAPCR-NYAGGYR---CDCPVGTV 536
+ C G YR C C +G V
Sbjct: 920 RWDEDECGVTLPGKYRMDVCCCSIGAV 946
Score = 87.0 bits (206), Expect = 4e-17
Identities = 39/106 (36%), Positives = 55/106 (51%), Gaps = 4/106 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDE--CAVRPPPCDQL-CHNTDGSYDCLCRTGYELDE 182
N +G +RC C G+ + + DE CA+ PP C C NT G + C+C +G++ D+
Sbjct: 2544 NQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQ 2603
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CV 317
C+DVDEC C C+NT G + C C GY + G CV
Sbjct: 2604 ALGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCV 2649
Score = 85.0 bits (201), Expect = 2e-16
Identities = 67/213 (31%), Positives = 90/213 (42%), Gaps = 37/213 (17%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPC-----DQLCHNTDGS------YD 149
R VNT GSFRC C G++P+ D +R PC +C + S +
Sbjct: 2267 RCVNTAGSFRCDCDEGFQPSPTLTECHD---IRQGPCFAEVLQTMCRSLSSSSEAVTRAE 2323
Query: 150 CLCRTG------YELDEDGANCRDVDECE---------RDTHTCQ---QICSNTE----- 260
C C G EL C RD C+ +C++ E
Sbjct: 2324 CCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSL 2383
Query: 261 GSYECSCEDGY--EKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGA 434
GS+ C C+ GY + C+D++EC + P C N GSF C CPRGY L+ +G
Sbjct: 2384 GSFRCHCQAGYTPDATATTCLDMDECSQVPK-PCTFLCKNTKGSFLCSCPRGYLLEEDGR 2442
Query: 435 RCVDRDEC-AQTGRCQAPCRNYAGGYRCDCPVG 530
C D DEC ++ CQ C N G + C CP G
Sbjct: 2443 TCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPG 2475
Score = 83.8 bits (198), Expect = 4e-16
Identities = 58/178 (32%), Positives = 76/178 (42%), Gaps = 5/178 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N+ GSF+C+C PG+ + G R D C + C + +
Sbjct: 1987 NSPGSFQCLCPPGFVLSDNGHRCFDTR-------QSFCFTRFEAGKCSVPKAFNTTKTRC 2039
Query: 192 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK---RGDACVDINECHEE-GVCPSP 359
C E C+ +++ C G+ D+ D+NEC E GVC +
Sbjct: 2040 CCSKRPG-EGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTN- 2097
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPVG 530
G CVN GSFRC CP GY LD G CVD DEC+ C Q C N GG+ C C G
Sbjct: 2098 GVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADG 2155
Score = 74.9 bits (176), Expect = 2e-13
Identities = 42/134 (31%), Positives = 57/134 (42%), Gaps = 5/134 (3%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCR--TGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECS 278
PC+ Y LC G++ + D+DEC+ CQ C NT GS++C
Sbjct: 1530 PCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCE 1589
Query: 279 CEDGYE--KRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRD 452
C GY + C DI+EC PG C N LG++ CVCP Y G C+D
Sbjct: 1590 CPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMR 1649
Query: 453 ECAQTGRCQAPCRN 494
+ C+N
Sbjct: 1650 KSVCFRHYNGTCQN 1663
Score = 72.9 bits (171), Expect = 7e-13
Identities = 54/178 (30%), Positives = 69/178 (38%), Gaps = 6/178 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNT-DGSYDCLCRTGYELDED 185
+NT GS+ C C + GV D R C H+ D C G +
Sbjct: 1461 INTPGSYLCSCPQDFELNPSGVGCVD---TRAGNCFLETHDRGDSGISCSAEIGVGVTRA 1517
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV--DINECHE-EGVCPS 356
C C + + TE C +G++ + DI+EC E G+C
Sbjct: 1518 SCCCSLGRAWGNPCELCP-MANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQG 1576
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRCDCP 524
G CVN GSF+C CP GY L C D DEC+ P C N G Y C CP
Sbjct: 1577 -GDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCP 1633
Score = 72.9 bits (171), Expect = 7e-13
Identities = 59/192 (30%), Positives = 84/192 (43%), Gaps = 12/192 (6%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECA-VRPPPC----DQLCHNTDGSYDC---LCRTG 167
NT+G++ CVC Y V G + C +R C + C N + +++ +C
Sbjct: 1623 NTLGNYTCVCPAEYLQ----VNGGNNCMDMRKSVCFRHYNGTCQN-ELAFNVTRKMCCCS 1677
Query: 168 YELDEDGANCRDVDECERDTHTCQQI-CSNTEGSYECSCEDGYEKRGDACVDINECHEEG 344
Y + + A R + C QI C N + G +DI+EC E
Sbjct: 1678 YNIGQ--AWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKP------LDIDECGEIP 1729
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQ--APCRNYAGGYRC 515
+ G C+N +GSFRC CP G+ ++ C D DEC ++ CQ A C N G YRC
Sbjct: 1730 AICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRC 1789
Query: 516 DCPVGTVRSPSG 551
C G SP G
Sbjct: 1790 KCTRGYKLSPGG 1801
Score = 70.5 bits (165), Expect = 4e-12
Identities = 56/185 (30%), Positives = 73/185 (39%), Gaps = 12/185 (6%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDE 182
N G FRC+C GY G +ECA P C + +C NT GSY C C +EL+
Sbjct: 1421 NLPGMFRCICNGGYELDRGGGNCTDINECA-DPVNCINGVCINTPGSYLCSCPQDFELNP 1479
Query: 183 DGANCRDV--DECERDTHTCQQICSNTEGSYECSCEDGYE-KRGDACVDINECHEEG--V 347
G C D C +TH + CS E G R C + +
Sbjct: 1480 SGVGCVDTRAGNCFLETH------DRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCEL 1533
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCV--DRDECAQT-GRCQA-PCRNYAGGYRC 515
CP +R +CP G + D DEC + G CQ C N G ++C
Sbjct: 1534 CPMANTT-----EYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQC 1588
Query: 516 DCPVG 530
+CP G
Sbjct: 1589 ECPPG 1593
Score = 59.3 bits (137), Expect = 9e-09
Identities = 58/201 (28%), Positives = 70/201 (34%), Gaps = 40/201 (19%)
Frame = +3
Query: 39 CGPGY-RPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDV-- 206
C G+ R G +EC P C C NT GS+ C C G LD G C DV
Sbjct: 855 CARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRL 914
Query: 207 DEC--ERDTHTCQQICSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCPS------ 356
+ C D C C C G + +AC D +CP
Sbjct: 915 EPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFAS 974
Query: 357 -------------------PGRCV-----NLLGSFRCVCPRGYRLDAEGARCVDRDEC-A 461
PG C N +GSF C C G+ LDA+ C D DEC
Sbjct: 975 RDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRI 1034
Query: 462 QTGRC-QAPCRNYAGGYRCDC 521
C Q C N G + C+C
Sbjct: 1035 SPDLCGQGTCVNTPGSFECEC 1055
Score = 53.6 bits (123), Expect = 4e-07
Identities = 30/80 (37%), Positives = 38/80 (47%), Gaps = 6/80 (7%)
Frame = +3
Query: 309 ACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD--RDECAQT---G 470
AC D++EC G+C G CVN++GSF C CP G+RL A C D C G
Sbjct: 244 ACQDVDECQAVPGLCQG-GSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGG 302
Query: 471 RCQAPCRNYAGGYRCDCPVG 530
RC + +C C G
Sbjct: 303 RCAGDLAGHYTRRQCCCDRG 322
Score = 52.0 bits (119), Expect = 1e-06
Identities = 26/72 (36%), Positives = 34/72 (47%)
Frame = +3
Query: 333 HEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYR 512
H +C + GRC+ S+RC C GY D G C+D DEC + C N G Y
Sbjct: 414 HFTNLCLN-GRCLPTPSSYRCECNVGYTQDVRG-ECIDVDECTSSPCHHGDCVNIPGTYH 471
Query: 513 CDCPVGTVRSPS 548
C C G +P+
Sbjct: 472 CRCYPGFQATPT 483
Score = 45.2 bits (102), Expect = 2e-04
Identities = 31/93 (33%), Positives = 42/93 (45%), Gaps = 8/93 (8%)
Frame = +3
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQ-QICSNTEGSYECSCEDGYEKRGDACVDINEC 332
CR G+ + C+DVDEC+ CQ C N GS+ C C G+ + E
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAA--CED 289
Query: 333 HEEGVCPS---PGRCV-NLLGSF---RCVCPRG 410
+ G C S GRC +L G + +C C RG
Sbjct: 290 YRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRG 322
Score = 42.7 bits (96), Expect = 8e-04
Identities = 44/147 (29%), Positives = 54/147 (36%), Gaps = 5/147 (3%)
Frame = +3
Query: 105 PPCDQLCHNTD---GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYEC 275
P CD+ CHN G C C G+ +CERD T C G C
Sbjct: 149 PICDRGCHNGGRCIGPNRCACVYGFM----------GPQCERDYRTGP--CFGQVGPEGC 196
Query: 276 SCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE 455
++ G C C G + G L + C RG+ + C D DE
Sbjct: 197 Q----HQLTGLVCTKALCCATVG--RAWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDE 250
Query: 456 C-AQTGRCQ-APCRNYAGGYRCDCPVG 530
C A G CQ C N G + C CPVG
Sbjct: 251 CQAVPGLCQGGSCVNMVGSFHCRCPVG 277
Score = 41.9 bits (94), Expect = 0.001
Identities = 43/144 (29%), Positives = 50/144 (34%), Gaps = 6/144 (4%)
Frame = +3
Query: 3 RGVNTIGS-FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELD 179
+G N GS F C PG+R GR +C V P C + C S LC
Sbjct: 55 QGPNVCGSRFHAYCCPGWRT----FPGRSQCVV--PICRRACGEGFCSQPNLCTCA---- 104
Query: 180 EDGANCRDVDECERDTHTCQQICSN--TEGSYECSCEDGYEKRGDAC---VDINECHEEG 344
DG C C N T C C+ GY G C + CH G
Sbjct: 105 -DGTLAPSCGVSRGSG--CSVSCMNGGTCRGASCLCQKGYT--GTVCGQPICDRGCHNGG 159
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYR 416
C P RC + G C R YR
Sbjct: 160 RCIGPNRCACVYGFMGPQCERDYR 183
Score = 35.1 bits (77), Expect = 0.17
Identities = 16/41 (39%), Positives = 19/41 (46%), Gaps = 1/41 (2%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRD 203
DEC P C C N GS+ C C G+ L + A C D
Sbjct: 249 DECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
>AY165864-1|AAO18146.1| 2809|Homo sapiens fibrillin-3 short form
precursor transcript variant 2 protein.
Length = 2809
Score = 184 bits (447), Expect = 2e-46
Identities = 81/177 (45%), Positives = 102/177 (57%), Gaps = 3/177 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+N++GSFRC C GY P DEC+ P PC LC NT GS+ C C GY L+E
Sbjct: 2380 INSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEE 2439
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECH-EEGVCPSP 359
DG C+D+DEC H CQ +C NT G++ C C G+ + AC D +EC + G C +
Sbjct: 2440 DGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAH 2499
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
G C N GSFRC C +G+ L + G C D +EC RCQ C+N GGYRC CP G
Sbjct: 2500 GHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGGYRCSCPQG 2556
Score = 163 bits (397), Expect = 3e-40
Identities = 78/186 (41%), Positives = 94/186 (50%), Gaps = 5/186 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELDE 182
VNT+G+F C C PG+ + DEC+ +P PC CHNT GS+ C C G+ L
Sbjct: 2462 VNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVS 2521
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPS 356
G C DV+EC+ H CQ C N G Y CSC G+ + CVD NEC
Sbjct: 2522 SGHGCEDVNECD-GPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCG 2580
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRCDCPVGT 533
C N LG FRCVCP G+ D C D DECA + G C C N GG+ C CP G
Sbjct: 2581 SASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGY 2640
Query: 534 VRSPSG 551
R+ G
Sbjct: 2641 FRAGQG 2646
Score = 161 bits (390), Expect = 2e-39
Identities = 82/189 (43%), Positives = 105/189 (55%), Gaps = 9/189 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
NT+GSF C C G+ R DEC + P C Q C NT GS++C C GYE
Sbjct: 1004 NTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGF 1063
Query: 183 D-GANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYE--KRGDACVDINECH-EEGV 347
NC DVDEC RD C+ C+NT+GSY+C C G+E +G AC DI+EC +G+
Sbjct: 1064 MLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGL 1123
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQAPCRNYAGGYRCDCP 524
CP G+CVN++G+F+C C G++ + CVD +EC Q G C C N G YRC C
Sbjct: 1124 CPH-GQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCG 1182
Query: 525 VGTVRSPSG 551
G P G
Sbjct: 1183 QGYSLMPDG 1191
Score = 150 bits (364), Expect = 3e-36
Identities = 81/189 (42%), Positives = 98/189 (51%), Gaps = 10/189 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA---GRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYEL 176
VNT GSF C C PGY + DECA P C C NTDGSY C C G+EL
Sbjct: 1045 VNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHEL 1104
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECH-EEG 344
G C D+DEC C C N G+++CSC G++ D CVDINEC + G
Sbjct: 1105 TAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNG 1164
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-C-QAPCRNYAGGYRCD 518
C C+N GS+RC C +GY L +G C D DEC + R C Q C N GG+RC
Sbjct: 1165 GCDV--HCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCL 1222
Query: 519 CPVGTVRSP 545
C G + +P
Sbjct: 1223 CYDGFMATP 1231
Score = 141 bits (342), Expect = 1e-33
Identities = 75/187 (40%), Positives = 90/187 (48%), Gaps = 6/187 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELDE 182
+N GSF C C PG+ G DEC + C C N GSY C CR G+
Sbjct: 1298 LNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFA--G 1355
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCP 353
DG C D DEC + C C N G Y C CE G++ D AC D++EC + +C
Sbjct: 1356 DGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLC- 1414
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPVG 530
+ G C NL G FRC+C GY LD G C D +ECA C C N G Y C CP
Sbjct: 1415 AFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQD 1474
Query: 531 TVRSPSG 551
+PSG
Sbjct: 1475 FELNPSG 1481
Score = 140 bits (340), Expect = 2e-33
Identities = 80/189 (42%), Positives = 98/189 (51%), Gaps = 9/189 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VNT GSFRC C GY G+ DEC+V P C N G ++C C G+E
Sbjct: 2101 VNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGL 2160
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINECHE-EGVCP 353
C D+DEC + C C NTEGSY C+C GY R D C D++EC + + C
Sbjct: 2161 M-MTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCH 2219
Query: 354 SPG-RCVNLLGSFRCVCPRGYR-LDAEGARCVDRDEC-AQTGRC-QAPCRNYAGGYRCDC 521
+ G C NL+G+F CVCP G R L G C D +EC AQ C C N AG +RCDC
Sbjct: 2220 ARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDC 2279
Query: 522 PVGTVRSPS 548
G SP+
Sbjct: 2280 DEGFQPSPT 2288
Score = 138 bits (335), Expect = 9e-33
Identities = 75/184 (40%), Positives = 91/184 (49%), Gaps = 8/184 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN IG+F+C C G++ P +G +EC V+ CD C NT+GSY C C GY L
Sbjct: 1130 VNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMP 1189
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCP 353
DG C DVDECE + C Q C+N G + C C DG+ D CVD++EC
Sbjct: 1190 DGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHIC 1249
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG-RC--QAPCRNYAGGYRCDCP 524
G C N GSF C C GY + C D DEC G C A C N G + C C
Sbjct: 1250 LHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCL 1309
Query: 525 VGTV 536
G V
Sbjct: 1310 PGWV 1313
Score = 132 bits (320), Expect = 6e-31
Identities = 65/152 (42%), Positives = 77/152 (50%), Gaps = 7/152 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA-GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
N IG F C C G+ P DEC++ P C CHNT+GSY C C GY L EDG
Sbjct: 2143 NVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDG 2202
Query: 189 ANCRDVDEC---ERDTHTCQQICSNTEGSYECSCEDGYEK---RGDACVDINECHEEGVC 350
A CRDVDEC ++D H C N G++ C C G G+ C D NECH +
Sbjct: 2203 AMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDL 2262
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
GRCVN GSFRC C G++ C D
Sbjct: 2263 CVNGRCVNTAGSFRCDCDEGFQPSPTLTECHD 2294
Score = 132 bits (319), Expect = 8e-31
Identities = 75/190 (39%), Positives = 104/190 (54%), Gaps = 9/190 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGV--RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
++T GS+ C+C G++ + DEC R P + C N GSY+CLC G+ +
Sbjct: 1822 MDTEGSYMCLCHRGFQASADQTLCMDIDECD-RQPCGNGTCKNIIGSYNCLCFPGFVVTH 1880
Query: 183 DGANCRDVDECERDT-HTCQ-QICSNTEGSYECSCEDGYEKRGDA--CVDINECHE-EGV 347
+G +C D DEC C+ C NT GS+ C C+DG+E D CVD NEC G
Sbjct: 1881 NG-DCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGT 1939
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQ-APCRNYAGGYRCDC 521
C PG C NL GSFRC+CP G+++ ++ C+D DEC++ C C N G ++C C
Sbjct: 1940 C-LPGTCQNLEGSFRCICPPGFQVQSD--HCIDIDECSEEPNLCLFGTCTNSPGSFQCLC 1996
Query: 522 PVGTVRSPSG 551
P G V S +G
Sbjct: 1997 PPGFVLSDNG 2006
Score = 132 bits (318), Expect = 1e-30
Identities = 65/180 (36%), Positives = 85/180 (47%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
NT GS++C C PG+ +G D EC++ C C N G++ C C G++
Sbjct: 1089 NTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTP 1148
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPS 356
D C D++EC C C NTEGSY CSC GY G AC D++EC E
Sbjct: 1149 DRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCD 1208
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-C-QAPCRNYAGGYRCDCPVG 530
G C N+ G RC+C G+ + CVD DEC C C N G + C C +G
Sbjct: 1209 QGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLG 1268
Score = 131 bits (316), Expect = 2e-30
Identities = 70/179 (39%), Positives = 90/179 (50%), Gaps = 9/179 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRG-VRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELDE 182
N IGS+ C+C PG+ G DEC + C NT GS+ CLC+ G+EL
Sbjct: 1863 NIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTA 1922
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSP 359
DG NC D +EC TC C N EGS+ C C G++ + D C+DI+EC EE
Sbjct: 1923 DGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDIDECSEEPNLCLF 1982
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE--C---AQTGRCQAPCRNYAGGYRCDC 521
G C N GSF+C+CP G+ L G RC D + C + G+C P RC C
Sbjct: 1983 GTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCC 2041
Score = 130 bits (314), Expect = 3e-30
Identities = 64/161 (39%), Positives = 82/161 (50%), Gaps = 7/161 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNT 257
+EC V P C C NT GS+ C C G+ LD NC D+DEC C Q C NT
Sbjct: 988 NECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNT 1047
Query: 258 EGSYECSCEDGYEKRG---DACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAE 428
GS+EC C GYE C+D++EC + + G C N GS++C CP G+ L A+
Sbjct: 1048 PGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAK 1107
Query: 429 GARCVDRDECA-QTGRC-QAPCRNYAGGYRCDCPVGTVRSP 545
G C D DEC+ G C C N G ++C C G +P
Sbjct: 1108 GTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTP 1148
Score = 127 bits (307), Expect = 2e-29
Identities = 69/156 (44%), Positives = 83/156 (53%), Gaps = 7/156 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNT 257
+ECA P C +C NTDGS+ C C GY LD G NC D DEC H C Q C+N
Sbjct: 2086 NECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVG-HPCGQGTCTNV 2144
Query: 258 EGSYECSCEDGYEK-RGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGA 434
G +EC+C DG+E C DI+EC + RC N GS+ C CP GY L +GA
Sbjct: 2145 IGGFECACADGFEPGLMMTCEDIDECSLNPLL-CAFRCHNTEGSYLCTCPAGYTLREDGA 2203
Query: 435 RCVDRDECAQTGR-CQA---PCRNYAGGYRCDCPVG 530
C D DECA + C A C+N G + C CP G
Sbjct: 2204 MCRDVDECADGQQDCHARGMECKNLIGTFACVCPPG 2239
Score = 126 bits (305), Expect = 4e-29
Identities = 67/182 (36%), Positives = 89/182 (48%), Gaps = 11/182 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD 179
VN G++ C C PG++ P + DEC V C C NT+GS+ C+C G+EL
Sbjct: 464 VNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELS 523
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINECHEEGVCP 353
DG NC D +EC T +C N +GS+ C C+ G+ G C+DI+EC G+C
Sbjct: 524 PDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICV 583
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVD---RDEC---AQTGRCQAPCRNYAGGYRC 515
+ G C N GSFRC C G + +G CVD R C + G C P C
Sbjct: 584 N-GHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSEC 642
Query: 516 DC 521
C
Sbjct: 643 CC 644
Score = 126 bits (304), Expect = 5e-29
Identities = 70/180 (38%), Positives = 82/180 (45%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELD 179
NT GSF C C GY R G DEC V CD C N GS+ C C G+
Sbjct: 1256 NTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWV-- 1313
Query: 180 EDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCP 353
DG C D+DEC H C C N GSY C+C G+ G C D +EC E
Sbjct: 1314 GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLC 1373
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ-APCRNYAGGYRCDCPVG 530
G+C+N G +RC C G+ + C D DECAQ C C N G +RC C G
Sbjct: 1374 DNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMFRCICNGG 1433
Score = 123 bits (297), Expect = 4e-28
Identities = 71/180 (39%), Positives = 90/180 (50%), Gaps = 7/180 (3%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C G GY GR V DEC + C C N+ GS+ C C+ GY D C D+D
Sbjct: 2351 CPHGSGYTAEGRDV---DECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMD 2407
Query: 210 ECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINEC-HEEGVCPSPGRCVNLL 380
EC + C +C NT+GS+ CSC GY E+ G C D++EC + C CVN +
Sbjct: 2408 ECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQF--LCVNTV 2465
Query: 381 GSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQA--PCRNYAGGYRCDCPVGTVRSPSG 551
G+F C CP G+ + C D DEC AQ G C A C N G +RC+C G SG
Sbjct: 2466 GAFTCRCPPGFTQHHQA--CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSG 2523
Score = 122 bits (295), Expect = 6e-28
Identities = 73/189 (38%), Positives = 88/189 (46%), Gaps = 6/189 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRG-VRGRDECAVRPPPCDQL-CHNTDGSYDCLCRTGYEL 176
R + T S+RC C GY RG DEC PC C N G+Y C C G++
Sbjct: 423 RCLPTPSSYRCECNVGYTQDVRGECIDVDECT--SSPCHHGDCVNIPGTYHCRCYPGFQA 480
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGV 347
C DVDEC C C NTEGS++C C G+E D CVD NEC +
Sbjct: 481 TPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTM 540
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCP 524
C + G C+N GSF C+C G+ L G C+D DEC G C C N G +RC C
Sbjct: 541 CVN-GVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCL 599
Query: 525 VGTVRSPSG 551
G G
Sbjct: 600 GGLAVGTDG 608
Score = 122 bits (294), Expect = 8e-28
Identities = 64/178 (35%), Positives = 83/178 (46%), Gaps = 4/178 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDED 185
+N GS+RC C G+ G RDECA CD C N G Y C C G++ ED
Sbjct: 1339 LNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTED 1398
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPSP 359
C+DVDEC + C N G + C C GYE + G C DINEC + C +
Sbjct: 1399 HRACQDVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCIN- 1457
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYA-GGYRCDCPVG 530
G C+N GS+ C CP+ + L+ G CVD + G C + G C +G
Sbjct: 1458 GVCINTPGSYLCSCPQDFELNPSGVGCVD----TRAGNCFLETHDRGDSGISCSAEIG 1511
Score = 122 bits (293), Expect = 1e-27
Identities = 73/184 (39%), Positives = 93/184 (50%), Gaps = 10/184 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPG--YRPAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYEL 176
+N IGSFRC C G Y DEC R PC Q C N GSY C C GY+L
Sbjct: 1738 INQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKL 1797
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGV 347
GA C +EC + C C +TEGSY C C G++ D C+DI+EC +
Sbjct: 1798 SPGGA-CVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQ-P 1855
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGR-CQ-APCRNYAGGYRCD 518
C + G C N++GS+ C+C G+ + G CVD DEC G+ C+ C N AG + C
Sbjct: 1856 CGN-GTCKNIIGSYNCLCFPGFVVTHNG-DCVDFDECTTLVGQVCRFGHCLNTAGSFHCL 1913
Query: 519 CPVG 530
C G
Sbjct: 1914 CQDG 1917
Score = 119 bits (286), Expect = 8e-27
Identities = 64/161 (39%), Positives = 82/161 (50%), Gaps = 5/161 (3%)
Frame = +3
Query: 84 DECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQI--CSN 254
DEC P C + +C N GS+ C C G+ + C DVDEC CQQ C N
Sbjct: 1723 DECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCIN 1782
Query: 255 TEGSYECSCEDGYE-KRGDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAE 428
GSY C C GY+ G ACV NEC E VC S G C++ GS+ C+C RG++ A+
Sbjct: 1783 IPGSYRCKCTRGYKLSPGGACVGRNECREIPNVC-SHGDCMDTEGSYMCLCHRGFQASAD 1841
Query: 429 GARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVRSPSG 551
C+D DEC + C+N G Y C C G V + +G
Sbjct: 1842 QTLCMDIDECDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNG 1882
Score = 109 bits (263), Expect = 5e-24
Identities = 65/175 (37%), Positives = 85/175 (48%), Gaps = 9/175 (5%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C G G GR + +ECA+ P C + +C N GSY C+C GYE G +C DVD
Sbjct: 670 CSSGLGITTDGRDI---NECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVD 726
Query: 210 ECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLL 380
EC ++ C C N+ GSY CSC G+ D C D++EC C S G C NL
Sbjct: 727 ECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP-CVS-GVCRNLA 784
Query: 381 GSFRCVCPRGYRLDAEGARCVD--RDEC---AQTGRCQAPCRNYAGGYRCDCPVG 530
GS+ C C G RLD G C+D + C Q RC+ + + C +G
Sbjct: 785 GSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLG 839
Score = 109 bits (262), Expect = 6e-24
Identities = 57/152 (37%), Positives = 71/152 (46%), Gaps = 4/152 (2%)
Frame = +3
Query: 108 PCDQLCH-NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSC 281
PC QLC + LC +G + DG RD++EC D C +C N GSY C C
Sbjct: 654 PC-QLCPAKNSAEFQALCSSGLGITTDG---RDINECALDPEVCANGVCENLRGSYRCVC 709
Query: 282 EDGYEK--RGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE 455
GYE G C D++EC + G C N GS+ C CP G+ + C D DE
Sbjct: 710 NLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDE 769
Query: 456 CAQTGRCQAPCRNYAGGYRCDCPVGTVRSPSG 551
C + CRN AG Y C C G+ PSG
Sbjct: 770 CLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSG 801
Score = 105 bits (251), Expect = 1e-22
Identities = 69/215 (32%), Positives = 96/215 (44%), Gaps = 35/215 (16%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRP---AGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELD 179
N IG+F CVC PG RP +G G +EC +P C + C NT GS+ C C G++
Sbjct: 2227 NLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPS 2286
Query: 180 EDGANCRDVDE--CERDT--HTCQQICSNTEG--SYECSCED--GYEKRGDACV------ 317
C D+ + C + C+ + S++E EC C G+ R + C
Sbjct: 2287 PTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSA 2346
Query: 318 ----------------DINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR 449
D++EC + G C+N LGSFRC C GY DA C+D
Sbjct: 2347 YRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDM 2406
Query: 450 DECAQTGR-CQAPCRNYAGGYRCDCPVGTVRSPSG 551
DEC+Q + C C+N G + C CP G + G
Sbjct: 2407 DECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDG 2441
Score = 99.1 bits (236), Expect = 9e-21
Identities = 72/219 (32%), Positives = 94/219 (42%), Gaps = 36/219 (16%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
R VNT GSF+CVC G+ P G+ +ECA + +C N DGS+ CLC+ G+ L
Sbjct: 504 RCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLL 563
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDI---NECH-- 335
G C D+DEC+ C+NTEGS+ C C G G CVD + C+
Sbjct: 564 APGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGA 623
Query: 336 -EEGVC--PSPGR-------CVN---------------LLGSFRCVCPRGYRLDAEGARC 440
E+G C P PG C N F+ +C G + +G
Sbjct: 624 IEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGR-- 681
Query: 441 VDRDECAQTGR--CQAPCRNYAGGYRCDCPVGTVRSPSG 551
D +ECA C N G YRC C +G SG
Sbjct: 682 -DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASG 719
Score = 97.5 bits (232), Expect = 3e-20
Identities = 71/209 (33%), Positives = 91/209 (43%), Gaps = 29/209 (13%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
N GS+RCVC GY +G+ DECA+ CD C N+ GSY C C G+ +
Sbjct: 700 NLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQ 759
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG--YEKRGDACVDINE--CH---EE 341
D C+DVDEC + +C N GSY C C G + G C+D + C +E
Sbjct: 760 DTEICKDVDEC-LSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQE 818
Query: 342 GVC-------PSPGRCVNLLGSF------RC----VCPRGYRLDAEGARCVDRDECAQ-T 467
C C LG+ RC C RG+ G C D +EC
Sbjct: 819 SRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGF-ARMTGVTCDDVNECESFP 877
Query: 468 GRC-QAPCRNYAGGYRCDCPVGTVRSPSG 551
G C C N AG +RC+CP G + SG
Sbjct: 878 GVCPNGRCVNTAGSFRCECPEGLMLDASG 906
Score = 88.2 bits (209), Expect = 2e-17
Identities = 73/207 (35%), Positives = 91/207 (43%), Gaps = 32/207 (15%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
N+ GS+ C C PG+ + DEC + P +C N GSY C C G LD
Sbjct: 742 NSPGSYSCSCPPGFHFWQDTEICKDVDEC-LSSPCVSGVCRNLAGSYTCKCGPGSRLDPS 800
Query: 186 GANCRD---------VDE--CERDTH--TCQQICSNTEGSY------EC----SCEDGYE 296
G C D + E CE + + + C T G+ C +C G+
Sbjct: 801 GTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFA 860
Query: 297 KR-GDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD-RDECAQT 467
+ G C D+NEC GVCP+ GRCVN GSFRC CP G LDA G CVD R E
Sbjct: 861 RMTGVTCDDVNECESFPGVCPN-GRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFL 919
Query: 468 GRCQAPCR-NYAGGYR---CDCPVGTV 536
+ C G YR C C +G V
Sbjct: 920 RWDEDECGVTLPGKYRMDVCCCSIGAV 946
Score = 87.0 bits (206), Expect = 4e-17
Identities = 39/106 (36%), Positives = 55/106 (51%), Gaps = 4/106 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDE--CAVRPPPCDQL-CHNTDGSYDCLCRTGYELDE 182
N +G +RC C G+ + + DE CA+ PP C C NT G + C+C +G++ D+
Sbjct: 2544 NQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQ 2603
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CV 317
C+DVDEC C C+NT G + C C GY + G CV
Sbjct: 2604 ALGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCV 2649
Score = 85.0 bits (201), Expect = 2e-16
Identities = 67/213 (31%), Positives = 90/213 (42%), Gaps = 37/213 (17%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPC-----DQLCHNTDGS------YD 149
R VNT GSFRC C G++P+ D +R PC +C + S +
Sbjct: 2267 RCVNTAGSFRCDCDEGFQPSPTLTECHD---IRQGPCFAEVLQTMCRSLSSSSEAVTRAE 2323
Query: 150 CLCRTG------YELDEDGANCRDVDECE---------RDTHTCQ---QICSNTE----- 260
C C G EL C RD C+ +C++ E
Sbjct: 2324 CCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSL 2383
Query: 261 GSYECSCEDGY--EKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGA 434
GS+ C C+ GY + C+D++EC + P C N GSF C CPRGY L+ +G
Sbjct: 2384 GSFRCHCQAGYTPDATATTCLDMDECSQVPK-PCTFLCKNTKGSFLCSCPRGYLLEEDGR 2442
Query: 435 RCVDRDEC-AQTGRCQAPCRNYAGGYRCDCPVG 530
C D DEC ++ CQ C N G + C CP G
Sbjct: 2443 TCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPG 2475
Score = 83.8 bits (198), Expect = 4e-16
Identities = 58/178 (32%), Positives = 76/178 (42%), Gaps = 5/178 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N+ GSF+C+C PG+ + G R D C + C + +
Sbjct: 1987 NSPGSFQCLCPPGFVLSDNGHRCFDTR-------QSFCFTRFEAGKCSVPKAFNTTKTRC 2039
Query: 192 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK---RGDACVDINECHEE-GVCPSP 359
C E C+ +++ C G+ D+ D+NEC E GVC +
Sbjct: 2040 CCSKRPG-EGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTN- 2097
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPVG 530
G CVN GSFRC CP GY LD G CVD DEC+ C Q C N GG+ C C G
Sbjct: 2098 GVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADG 2155
Score = 74.9 bits (176), Expect = 2e-13
Identities = 42/134 (31%), Positives = 57/134 (42%), Gaps = 5/134 (3%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCR--TGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECS 278
PC+ Y LC G++ + D+DEC+ CQ C NT GS++C
Sbjct: 1530 PCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCE 1589
Query: 279 CEDGYE--KRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRD 452
C GY + C DI+EC PG C N LG++ CVCP Y G C+D
Sbjct: 1590 CPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMR 1649
Query: 453 ECAQTGRCQAPCRN 494
+ C+N
Sbjct: 1650 KSVCFRHYNGTCQN 1663
Score = 72.9 bits (171), Expect = 7e-13
Identities = 54/178 (30%), Positives = 69/178 (38%), Gaps = 6/178 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNT-DGSYDCLCRTGYELDED 185
+NT GS+ C C + GV D R C H+ D C G +
Sbjct: 1461 INTPGSYLCSCPQDFELNPSGVGCVD---TRAGNCFLETHDRGDSGISCSAEIGVGVTRA 1517
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV--DINECHE-EGVCPS 356
C C + + TE C +G++ + DI+EC E G+C
Sbjct: 1518 SCCCSLGRAWGNPCELCP-MANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQG 1576
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRCDCP 524
G CVN GSF+C CP GY L C D DEC+ P C N G Y C CP
Sbjct: 1577 -GDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCP 1633
Score = 72.9 bits (171), Expect = 7e-13
Identities = 59/192 (30%), Positives = 84/192 (43%), Gaps = 12/192 (6%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECA-VRPPPC----DQLCHNTDGSYDC---LCRTG 167
NT+G++ CVC Y V G + C +R C + C N + +++ +C
Sbjct: 1623 NTLGNYTCVCPAEYLQ----VNGGNNCMDMRKSVCFRHYNGTCQN-ELAFNVTRKMCCCS 1677
Query: 168 YELDEDGANCRDVDECERDTHTCQQI-CSNTEGSYECSCEDGYEKRGDACVDINECHEEG 344
Y + + A R + C QI C N + G +DI+EC E
Sbjct: 1678 YNIGQ--AWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKP------LDIDECGEIP 1729
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQ--APCRNYAGGYRC 515
+ G C+N +GSFRC CP G+ ++ C D DEC ++ CQ A C N G YRC
Sbjct: 1730 AICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRC 1789
Query: 516 DCPVGTVRSPSG 551
C G SP G
Sbjct: 1790 KCTRGYKLSPGG 1801
Score = 70.5 bits (165), Expect = 4e-12
Identities = 56/185 (30%), Positives = 73/185 (39%), Gaps = 12/185 (6%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDE 182
N G FRC+C GY G +ECA P C + +C NT GSY C C +EL+
Sbjct: 1421 NLPGMFRCICNGGYELDRGGGNCTDINECA-DPVNCINGVCINTPGSYLCSCPQDFELNP 1479
Query: 183 DGANCRDV--DECERDTHTCQQICSNTEGSYECSCEDGYE-KRGDACVDINECHEEG--V 347
G C D C +TH + CS E G R C + +
Sbjct: 1480 SGVGCVDTRAGNCFLETH------DRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCEL 1533
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCV--DRDECAQT-GRCQA-PCRNYAGGYRC 515
CP +R +CP G + D DEC + G CQ C N G ++C
Sbjct: 1534 CPMANTT-----EYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQC 1588
Query: 516 DCPVG 530
+CP G
Sbjct: 1589 ECPPG 1593
Score = 59.3 bits (137), Expect = 9e-09
Identities = 58/201 (28%), Positives = 70/201 (34%), Gaps = 40/201 (19%)
Frame = +3
Query: 39 CGPGY-RPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDV-- 206
C G+ R G +EC P C C NT GS+ C C G LD G C DV
Sbjct: 855 CARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRL 914
Query: 207 DEC--ERDTHTCQQICSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCPS------ 356
+ C D C C C G + +AC D +CP
Sbjct: 915 EPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFAS 974
Query: 357 -------------------PGRCV-----NLLGSFRCVCPRGYRLDAEGARCVDRDEC-A 461
PG C N +GSF C C G+ LDA+ C D DEC
Sbjct: 975 RDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRI 1034
Query: 462 QTGRC-QAPCRNYAGGYRCDC 521
C Q C N G + C+C
Sbjct: 1035 SPDLCGQGTCVNTPGSFECEC 1055
Score = 53.6 bits (123), Expect = 4e-07
Identities = 30/80 (37%), Positives = 38/80 (47%), Gaps = 6/80 (7%)
Frame = +3
Query: 309 ACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD--RDECAQT---G 470
AC D++EC G+C G CVN++GSF C CP G+RL A C D C G
Sbjct: 244 ACQDVDECQAVPGLCQG-GSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGG 302
Query: 471 RCQAPCRNYAGGYRCDCPVG 530
RC + +C C G
Sbjct: 303 RCAGDLAGHYTRRQCCCDRG 322
Score = 52.0 bits (119), Expect = 1e-06
Identities = 26/72 (36%), Positives = 34/72 (47%)
Frame = +3
Query: 333 HEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYR 512
H +C + GRC+ S+RC C GY D G C+D DEC + C N G Y
Sbjct: 414 HFTNLCLN-GRCLPTPSSYRCECNVGYTQDVRG-ECIDVDECTSSPCHHGDCVNIPGTYH 471
Query: 513 CDCPVGTVRSPS 548
C C G +P+
Sbjct: 472 CRCYPGFQATPT 483
Score = 45.2 bits (102), Expect = 2e-04
Identities = 31/93 (33%), Positives = 42/93 (45%), Gaps = 8/93 (8%)
Frame = +3
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQ-QICSNTEGSYECSCEDGYEKRGDACVDINEC 332
CR G+ + C+DVDEC+ CQ C N GS+ C C G+ + E
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAA--CED 289
Query: 333 HEEGVCPS---PGRCV-NLLGSF---RCVCPRG 410
+ G C S GRC +L G + +C C RG
Sbjct: 290 YRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRG 322
Score = 42.7 bits (96), Expect = 8e-04
Identities = 44/147 (29%), Positives = 54/147 (36%), Gaps = 5/147 (3%)
Frame = +3
Query: 105 PPCDQLCHNTD---GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYEC 275
P CD+ CHN G C C G+ +CERD T C G C
Sbjct: 149 PICDRGCHNGGRCIGPNRCACVYGFM----------GPQCERDYRTGP--CFGQVGPEGC 196
Query: 276 SCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE 455
++ G C C G + G L + C RG+ + C D DE
Sbjct: 197 Q----HQLTGLVCTKALCCATVG--RAWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDE 250
Query: 456 C-AQTGRCQ-APCRNYAGGYRCDCPVG 530
C A G CQ C N G + C CPVG
Sbjct: 251 CQAVPGLCQGGSCVNMVGSFHCRCPVG 277
Score = 41.9 bits (94), Expect = 0.001
Identities = 43/144 (29%), Positives = 50/144 (34%), Gaps = 6/144 (4%)
Frame = +3
Query: 3 RGVNTIGS-FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELD 179
+G N GS F C PG+R GR +C V P C + C S LC
Sbjct: 55 QGPNVCGSRFHAYCCPGWRT----FPGRSQCVV--PICRRACGEGFCSQPNLCTCA---- 104
Query: 180 EDGANCRDVDECERDTHTCQQICSN--TEGSYECSCEDGYEKRGDAC---VDINECHEEG 344
DG C C N T C C+ GY G C + CH G
Sbjct: 105 -DGTLAPSCGVSRGSG--CSVSCMNGGTCRGASCLCQKGYT--GTVCGQPICDRGCHNGG 159
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYR 416
C P RC + G C R YR
Sbjct: 160 RCIGPNRCACVYGFMGPQCERDYR 183
Score = 35.1 bits (77), Expect = 0.17
Identities = 16/41 (39%), Positives = 19/41 (46%), Gaps = 1/41 (2%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRD 203
DEC P C C N GS+ C C G+ L + A C D
Sbjct: 249 DECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
>AY165863-1|AAO18145.1| 2809|Homo sapiens fibrillin-3 short form
precursor transcript variant 1 protein.
Length = 2809
Score = 184 bits (447), Expect = 2e-46
Identities = 81/177 (45%), Positives = 102/177 (57%), Gaps = 3/177 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+N++GSFRC C GY P DEC+ P PC LC NT GS+ C C GY L+E
Sbjct: 2380 INSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEE 2439
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECH-EEGVCPSP 359
DG C+D+DEC H CQ +C NT G++ C C G+ + AC D +EC + G C +
Sbjct: 2440 DGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAH 2499
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
G C N GSFRC C +G+ L + G C D +EC RCQ C+N GGYRC CP G
Sbjct: 2500 GHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGGYRCSCPQG 2556
Score = 163 bits (397), Expect = 3e-40
Identities = 78/186 (41%), Positives = 94/186 (50%), Gaps = 5/186 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELDE 182
VNT+G+F C C PG+ + DEC+ +P PC CHNT GS+ C C G+ L
Sbjct: 2462 VNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVS 2521
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPS 356
G C DV+EC+ H CQ C N G Y CSC G+ + CVD NEC
Sbjct: 2522 SGHGCEDVNECD-GPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCG 2580
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRCDCPVGT 533
C N LG FRCVCP G+ D C D DECA + G C C N GG+ C CP G
Sbjct: 2581 SASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGY 2640
Query: 534 VRSPSG 551
R+ G
Sbjct: 2641 FRAGQG 2646
Score = 161 bits (390), Expect = 2e-39
Identities = 82/189 (43%), Positives = 105/189 (55%), Gaps = 9/189 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
NT+GSF C C G+ R DEC + P C Q C NT GS++C C GYE
Sbjct: 1004 NTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGF 1063
Query: 183 D-GANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYE--KRGDACVDINECH-EEGV 347
NC DVDEC RD C+ C+NT+GSY+C C G+E +G AC DI+EC +G+
Sbjct: 1064 MLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGL 1123
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQAPCRNYAGGYRCDCP 524
CP G+CVN++G+F+C C G++ + CVD +EC Q G C C N G YRC C
Sbjct: 1124 CPH-GQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCG 1182
Query: 525 VGTVRSPSG 551
G P G
Sbjct: 1183 QGYSLMPDG 1191
Score = 150 bits (364), Expect = 3e-36
Identities = 81/189 (42%), Positives = 98/189 (51%), Gaps = 10/189 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA---GRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYEL 176
VNT GSF C C PGY + DECA P C C NTDGSY C C G+EL
Sbjct: 1045 VNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHEL 1104
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECH-EEG 344
G C D+DEC C C N G+++CSC G++ D CVDINEC + G
Sbjct: 1105 TAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNG 1164
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-C-QAPCRNYAGGYRCD 518
C C+N GS+RC C +GY L +G C D DEC + R C Q C N GG+RC
Sbjct: 1165 GCDV--HCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCL 1222
Query: 519 CPVGTVRSP 545
C G + +P
Sbjct: 1223 CYDGFMATP 1231
Score = 141 bits (342), Expect = 1e-33
Identities = 75/187 (40%), Positives = 90/187 (48%), Gaps = 6/187 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELDE 182
+N GSF C C PG+ G DEC + C C N GSY C CR G+
Sbjct: 1298 LNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFA--G 1355
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCP 353
DG C D DEC + C C N G Y C CE G++ D AC D++EC + +C
Sbjct: 1356 DGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLC- 1414
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPVG 530
+ G C NL G FRC+C GY LD G C D +ECA C C N G Y C CP
Sbjct: 1415 AFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQD 1474
Query: 531 TVRSPSG 551
+PSG
Sbjct: 1475 FELNPSG 1481
Score = 140 bits (340), Expect = 2e-33
Identities = 80/189 (42%), Positives = 98/189 (51%), Gaps = 9/189 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VNT GSFRC C GY G+ DEC+V P C N G ++C C G+E
Sbjct: 2101 VNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGL 2160
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINECHE-EGVCP 353
C D+DEC + C C NTEGSY C+C GY R D C D++EC + + C
Sbjct: 2161 M-MTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCH 2219
Query: 354 SPG-RCVNLLGSFRCVCPRGYR-LDAEGARCVDRDEC-AQTGRC-QAPCRNYAGGYRCDC 521
+ G C NL+G+F CVCP G R L G C D +EC AQ C C N AG +RCDC
Sbjct: 2220 ARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDC 2279
Query: 522 PVGTVRSPS 548
G SP+
Sbjct: 2280 DEGFQPSPT 2288
Score = 138 bits (335), Expect = 9e-33
Identities = 75/184 (40%), Positives = 91/184 (49%), Gaps = 8/184 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN IG+F+C C G++ P +G +EC V+ CD C NT+GSY C C GY L
Sbjct: 1130 VNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMP 1189
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCP 353
DG C DVDECE + C Q C+N G + C C DG+ D CVD++EC
Sbjct: 1190 DGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHIC 1249
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG-RC--QAPCRNYAGGYRCDCP 524
G C N GSF C C GY + C D DEC G C A C N G + C C
Sbjct: 1250 LHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCL 1309
Query: 525 VGTV 536
G V
Sbjct: 1310 PGWV 1313
Score = 132 bits (320), Expect = 6e-31
Identities = 65/152 (42%), Positives = 77/152 (50%), Gaps = 7/152 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA-GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
N IG F C C G+ P DEC++ P C CHNT+GSY C C GY L EDG
Sbjct: 2143 NVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDG 2202
Query: 189 ANCRDVDEC---ERDTHTCQQICSNTEGSYECSCEDGYEK---RGDACVDINECHEEGVC 350
A CRDVDEC ++D H C N G++ C C G G+ C D NECH +
Sbjct: 2203 AMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDL 2262
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
GRCVN GSFRC C G++ C D
Sbjct: 2263 CVNGRCVNTAGSFRCDCDEGFQPSPTLTECHD 2294
Score = 132 bits (319), Expect = 8e-31
Identities = 75/190 (39%), Positives = 104/190 (54%), Gaps = 9/190 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGV--RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
++T GS+ C+C G++ + DEC R P + C N GSY+CLC G+ +
Sbjct: 1822 MDTEGSYMCLCHRGFQASADQTLCMDIDECD-RQPCGNGTCKNIIGSYNCLCFPGFVVTH 1880
Query: 183 DGANCRDVDECERDT-HTCQ-QICSNTEGSYECSCEDGYEKRGDA--CVDINECHE-EGV 347
+G +C D DEC C+ C NT GS+ C C+DG+E D CVD NEC G
Sbjct: 1881 NG-DCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGT 1939
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQ-APCRNYAGGYRCDC 521
C PG C NL GSFRC+CP G+++ ++ C+D DEC++ C C N G ++C C
Sbjct: 1940 C-LPGTCQNLEGSFRCICPPGFQVQSD--HCIDIDECSEEPNLCLFGTCTNSPGSFQCLC 1996
Query: 522 PVGTVRSPSG 551
P G V S +G
Sbjct: 1997 PPGFVLSDNG 2006
Score = 132 bits (318), Expect = 1e-30
Identities = 65/180 (36%), Positives = 85/180 (47%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
NT GS++C C PG+ +G D EC++ C C N G++ C C G++
Sbjct: 1089 NTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTP 1148
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPS 356
D C D++EC C C NTEGSY CSC GY G AC D++EC E
Sbjct: 1149 DRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCD 1208
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-C-QAPCRNYAGGYRCDCPVG 530
G C N+ G RC+C G+ + CVD DEC C C N G + C C +G
Sbjct: 1209 QGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLG 1268
Score = 131 bits (316), Expect = 2e-30
Identities = 70/179 (39%), Positives = 90/179 (50%), Gaps = 9/179 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRG-VRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELDE 182
N IGS+ C+C PG+ G DEC + C NT GS+ CLC+ G+EL
Sbjct: 1863 NIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTA 1922
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSP 359
DG NC D +EC TC C N EGS+ C C G++ + D C+DI+EC EE
Sbjct: 1923 DGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDIDECSEEPNLCLF 1982
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE--C---AQTGRCQAPCRNYAGGYRCDC 521
G C N GSF+C+CP G+ L G RC D + C + G+C P RC C
Sbjct: 1983 GTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCC 2041
Score = 130 bits (314), Expect = 3e-30
Identities = 64/161 (39%), Positives = 82/161 (50%), Gaps = 7/161 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNT 257
+EC V P C C NT GS+ C C G+ LD NC D+DEC C Q C NT
Sbjct: 988 NECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNT 1047
Query: 258 EGSYECSCEDGYEKRG---DACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAE 428
GS+EC C GYE C+D++EC + + G C N GS++C CP G+ L A+
Sbjct: 1048 PGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAK 1107
Query: 429 GARCVDRDECA-QTGRC-QAPCRNYAGGYRCDCPVGTVRSP 545
G C D DEC+ G C C N G ++C C G +P
Sbjct: 1108 GTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTP 1148
Score = 127 bits (307), Expect = 2e-29
Identities = 69/156 (44%), Positives = 83/156 (53%), Gaps = 7/156 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNT 257
+ECA P C +C NTDGS+ C C GY LD G NC D DEC H C Q C+N
Sbjct: 2086 NECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVG-HPCGQGTCTNV 2144
Query: 258 EGSYECSCEDGYEK-RGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGA 434
G +EC+C DG+E C DI+EC + RC N GS+ C CP GY L +GA
Sbjct: 2145 IGGFECACADGFEPGLMMTCEDIDECSLNPLL-CAFRCHNTEGSYLCTCPAGYTLREDGA 2203
Query: 435 RCVDRDECAQTGR-CQA---PCRNYAGGYRCDCPVG 530
C D DECA + C A C+N G + C CP G
Sbjct: 2204 MCRDVDECADGQQDCHARGMECKNLIGTFACVCPPG 2239
Score = 126 bits (305), Expect = 4e-29
Identities = 67/182 (36%), Positives = 89/182 (48%), Gaps = 11/182 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD 179
VN G++ C C PG++ P + DEC V C C NT+GS+ C+C G+EL
Sbjct: 464 VNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELS 523
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINECHEEGVCP 353
DG NC D +EC T +C N +GS+ C C+ G+ G C+DI+EC G+C
Sbjct: 524 PDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICV 583
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVD---RDEC---AQTGRCQAPCRNYAGGYRC 515
+ G C N GSFRC C G + +G CVD R C + G C P C
Sbjct: 584 N-GHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSEC 642
Query: 516 DC 521
C
Sbjct: 643 CC 644
Score = 126 bits (304), Expect = 5e-29
Identities = 70/180 (38%), Positives = 82/180 (45%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELD 179
NT GSF C C GY R G DEC V CD C N GS+ C C G+
Sbjct: 1256 NTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWV-- 1313
Query: 180 EDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCP 353
DG C D+DEC H C C N GSY C+C G+ G C D +EC E
Sbjct: 1314 GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLC 1373
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ-APCRNYAGGYRCDCPVG 530
G+C+N G +RC C G+ + C D DECAQ C C N G +RC C G
Sbjct: 1374 DNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMFRCICNGG 1433
Score = 123 bits (297), Expect = 4e-28
Identities = 71/180 (39%), Positives = 90/180 (50%), Gaps = 7/180 (3%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C G GY GR V DEC + C C N+ GS+ C C+ GY D C D+D
Sbjct: 2351 CPHGSGYTAEGRDV---DECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMD 2407
Query: 210 ECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINEC-HEEGVCPSPGRCVNLL 380
EC + C +C NT+GS+ CSC GY E+ G C D++EC + C CVN +
Sbjct: 2408 ECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQF--LCVNTV 2465
Query: 381 GSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQA--PCRNYAGGYRCDCPVGTVRSPSG 551
G+F C CP G+ + C D DEC AQ G C A C N G +RC+C G SG
Sbjct: 2466 GAFTCRCPPGFTQHHQA--CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSG 2523
Score = 122 bits (295), Expect = 6e-28
Identities = 73/189 (38%), Positives = 88/189 (46%), Gaps = 6/189 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRG-VRGRDECAVRPPPCDQL-CHNTDGSYDCLCRTGYEL 176
R + T S+RC C GY RG DEC PC C N G+Y C C G++
Sbjct: 423 RCLPTPSSYRCECNVGYTQDVRGECIDVDECT--SSPCHHGDCVNIPGTYHCRCYPGFQA 480
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGV 347
C DVDEC C C NTEGS++C C G+E D CVD NEC +
Sbjct: 481 TPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTM 540
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCP 524
C + G C+N GSF C+C G+ L G C+D DEC G C C N G +RC C
Sbjct: 541 CVN-GVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCL 599
Query: 525 VGTVRSPSG 551
G G
Sbjct: 600 GGLAVGTDG 608
Score = 122 bits (294), Expect = 8e-28
Identities = 64/178 (35%), Positives = 83/178 (46%), Gaps = 4/178 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDED 185
+N GS+RC C G+ G RDECA CD C N G Y C C G++ ED
Sbjct: 1339 LNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTED 1398
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPSP 359
C+DVDEC + C N G + C C GYE + G C DINEC + C +
Sbjct: 1399 HRACQDVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCIN- 1457
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYA-GGYRCDCPVG 530
G C+N GS+ C CP+ + L+ G CVD + G C + G C +G
Sbjct: 1458 GVCINTPGSYLCSCPQDFELNPSGVGCVD----TRAGNCFLETHDRGDSGISCSAEIG 1511
Score = 122 bits (293), Expect = 1e-27
Identities = 73/184 (39%), Positives = 93/184 (50%), Gaps = 10/184 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPG--YRPAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYEL 176
+N IGSFRC C G Y DEC R PC Q C N GSY C C GY+L
Sbjct: 1738 INQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKL 1797
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGV 347
GA C +EC + C C +TEGSY C C G++ D C+DI+EC +
Sbjct: 1798 SPGGA-CVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQ-P 1855
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGR-CQ-APCRNYAGGYRCD 518
C + G C N++GS+ C+C G+ + G CVD DEC G+ C+ C N AG + C
Sbjct: 1856 CGN-GTCKNIIGSYNCLCFPGFVVTHNG-DCVDFDECTTLVGQVCRFGHCLNTAGSFHCL 1913
Query: 519 CPVG 530
C G
Sbjct: 1914 CQDG 1917
Score = 119 bits (286), Expect = 8e-27
Identities = 64/161 (39%), Positives = 82/161 (50%), Gaps = 5/161 (3%)
Frame = +3
Query: 84 DECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQI--CSN 254
DEC P C + +C N GS+ C C G+ + C DVDEC CQQ C N
Sbjct: 1723 DECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCIN 1782
Query: 255 TEGSYECSCEDGYE-KRGDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAE 428
GSY C C GY+ G ACV NEC E VC S G C++ GS+ C+C RG++ A+
Sbjct: 1783 IPGSYRCKCTRGYKLSPGGACVGRNECREIPNVC-SHGDCMDTEGSYMCLCHRGFQASAD 1841
Query: 429 GARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVRSPSG 551
C+D DEC + C+N G Y C C G V + +G
Sbjct: 1842 QTLCMDIDECDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNG 1882
Score = 109 bits (263), Expect = 5e-24
Identities = 65/175 (37%), Positives = 85/175 (48%), Gaps = 9/175 (5%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C G G GR + +ECA+ P C + +C N GSY C+C GYE G +C DVD
Sbjct: 670 CSSGLGITTDGRDI---NECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVD 726
Query: 210 ECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLL 380
EC ++ C C N+ GSY CSC G+ D C D++EC C S G C NL
Sbjct: 727 ECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP-CVS-GVCRNLA 784
Query: 381 GSFRCVCPRGYRLDAEGARCVD--RDEC---AQTGRCQAPCRNYAGGYRCDCPVG 530
GS+ C C G RLD G C+D + C Q RC+ + + C +G
Sbjct: 785 GSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLG 839
Score = 109 bits (262), Expect = 6e-24
Identities = 57/152 (37%), Positives = 71/152 (46%), Gaps = 4/152 (2%)
Frame = +3
Query: 108 PCDQLCH-NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSC 281
PC QLC + LC +G + DG RD++EC D C +C N GSY C C
Sbjct: 654 PC-QLCPAKNSAEFQALCSSGLGITTDG---RDINECALDPEVCANGVCENLRGSYRCVC 709
Query: 282 EDGYEK--RGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE 455
GYE G C D++EC + G C N GS+ C CP G+ + C D DE
Sbjct: 710 NLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDE 769
Query: 456 CAQTGRCQAPCRNYAGGYRCDCPVGTVRSPSG 551
C + CRN AG Y C C G+ PSG
Sbjct: 770 CLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSG 801
Score = 105 bits (251), Expect = 1e-22
Identities = 69/215 (32%), Positives = 96/215 (44%), Gaps = 35/215 (16%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRP---AGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELD 179
N IG+F CVC PG RP +G G +EC +P C + C NT GS+ C C G++
Sbjct: 2227 NLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPS 2286
Query: 180 EDGANCRDVDE--CERDT--HTCQQICSNTEG--SYECSCED--GYEKRGDACV------ 317
C D+ + C + C+ + S++E EC C G+ R + C
Sbjct: 2287 PTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSA 2346
Query: 318 ----------------DINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR 449
D++EC + G C+N LGSFRC C GY DA C+D
Sbjct: 2347 YRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDM 2406
Query: 450 DECAQTGR-CQAPCRNYAGGYRCDCPVGTVRSPSG 551
DEC+Q + C C+N G + C CP G + G
Sbjct: 2407 DECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDG 2441
Score = 99.1 bits (236), Expect = 9e-21
Identities = 72/219 (32%), Positives = 94/219 (42%), Gaps = 36/219 (16%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
R VNT GSF+CVC G+ P G+ +ECA + +C N DGS+ CLC+ G+ L
Sbjct: 504 RCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLL 563
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDI---NECH-- 335
G C D+DEC+ C+NTEGS+ C C G G CVD + C+
Sbjct: 564 APGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGA 623
Query: 336 -EEGVC--PSPGR-------CVN---------------LLGSFRCVCPRGYRLDAEGARC 440
E+G C P PG C N F+ +C G + +G
Sbjct: 624 IEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGR-- 681
Query: 441 VDRDECAQTGR--CQAPCRNYAGGYRCDCPVGTVRSPSG 551
D +ECA C N G YRC C +G SG
Sbjct: 682 -DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASG 719
Score = 97.5 bits (232), Expect = 3e-20
Identities = 71/209 (33%), Positives = 91/209 (43%), Gaps = 29/209 (13%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
N GS+RCVC GY +G+ DECA+ CD C N+ GSY C C G+ +
Sbjct: 700 NLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQ 759
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG--YEKRGDACVDINE--CH---EE 341
D C+DVDEC + +C N GSY C C G + G C+D + C +E
Sbjct: 760 DTEICKDVDEC-LSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQE 818
Query: 342 GVC-------PSPGRCVNLLGSF------RC----VCPRGYRLDAEGARCVDRDECAQ-T 467
C C LG+ RC C RG+ G C D +EC
Sbjct: 819 SRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGF-ARMTGVTCDDVNECESFP 877
Query: 468 GRC-QAPCRNYAGGYRCDCPVGTVRSPSG 551
G C C N AG +RC+CP G + SG
Sbjct: 878 GVCPNGRCVNTAGSFRCECPEGLMLDASG 906
Score = 88.2 bits (209), Expect = 2e-17
Identities = 73/207 (35%), Positives = 91/207 (43%), Gaps = 32/207 (15%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
N+ GS+ C C PG+ + DEC + P +C N GSY C C G LD
Sbjct: 742 NSPGSYSCSCPPGFHFWQDTEICKDVDEC-LSSPCVSGVCRNLAGSYTCKCGPGSRLDPS 800
Query: 186 GANCRD---------VDE--CERDTH--TCQQICSNTEGSY------EC----SCEDGYE 296
G C D + E CE + + + C T G+ C +C G+
Sbjct: 801 GTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFA 860
Query: 297 KR-GDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD-RDECAQT 467
+ G C D+NEC GVCP+ GRCVN GSFRC CP G LDA G CVD R E
Sbjct: 861 RMTGVTCDDVNECESFPGVCPN-GRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFL 919
Query: 468 GRCQAPCR-NYAGGYR---CDCPVGTV 536
+ C G YR C C +G V
Sbjct: 920 RWDEDECGVTLPGKYRMDVCCCSIGAV 946
Score = 87.0 bits (206), Expect = 4e-17
Identities = 39/106 (36%), Positives = 55/106 (51%), Gaps = 4/106 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDE--CAVRPPPCDQL-CHNTDGSYDCLCRTGYELDE 182
N +G +RC C G+ + + DE CA+ PP C C NT G + C+C +G++ D+
Sbjct: 2544 NQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQ 2603
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CV 317
C+DVDEC C C+NT G + C C GY + G CV
Sbjct: 2604 ALGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCV 2649
Score = 85.0 bits (201), Expect = 2e-16
Identities = 67/213 (31%), Positives = 90/213 (42%), Gaps = 37/213 (17%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPC-----DQLCHNTDGS------YD 149
R VNT GSFRC C G++P+ D +R PC +C + S +
Sbjct: 2267 RCVNTAGSFRCDCDEGFQPSPTLTECHD---IRQGPCFAEVLQTMCRSLSSSSEAVTRAE 2323
Query: 150 CLCRTG------YELDEDGANCRDVDECE---------RDTHTCQ---QICSNTE----- 260
C C G EL C RD C+ +C++ E
Sbjct: 2324 CCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSL 2383
Query: 261 GSYECSCEDGY--EKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGA 434
GS+ C C+ GY + C+D++EC + P C N GSF C CPRGY L+ +G
Sbjct: 2384 GSFRCHCQAGYTPDATATTCLDMDECSQVPK-PCTFLCKNTKGSFLCSCPRGYLLEEDGR 2442
Query: 435 RCVDRDEC-AQTGRCQAPCRNYAGGYRCDCPVG 530
C D DEC ++ CQ C N G + C CP G
Sbjct: 2443 TCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPG 2475
Score = 83.8 bits (198), Expect = 4e-16
Identities = 58/178 (32%), Positives = 76/178 (42%), Gaps = 5/178 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N+ GSF+C+C PG+ + G R D C + C + +
Sbjct: 1987 NSPGSFQCLCPPGFVLSDNGHRCFDTR-------QSFCFTRFEAGKCSVPKAFNTTKTRC 2039
Query: 192 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK---RGDACVDINECHEE-GVCPSP 359
C E C+ +++ C G+ D+ D+NEC E GVC +
Sbjct: 2040 CCSKRPG-EGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTN- 2097
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPVG 530
G CVN GSFRC CP GY LD G CVD DEC+ C Q C N GG+ C C G
Sbjct: 2098 GVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADG 2155
Score = 74.9 bits (176), Expect = 2e-13
Identities = 42/134 (31%), Positives = 57/134 (42%), Gaps = 5/134 (3%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCR--TGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECS 278
PC+ Y LC G++ + D+DEC+ CQ C NT GS++C
Sbjct: 1530 PCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCE 1589
Query: 279 CEDGYE--KRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRD 452
C GY + C DI+EC PG C N LG++ CVCP Y G C+D
Sbjct: 1590 CPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMR 1649
Query: 453 ECAQTGRCQAPCRN 494
+ C+N
Sbjct: 1650 KSVCFRHYNGTCQN 1663
Score = 72.9 bits (171), Expect = 7e-13
Identities = 54/178 (30%), Positives = 69/178 (38%), Gaps = 6/178 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNT-DGSYDCLCRTGYELDED 185
+NT GS+ C C + GV D R C H+ D C G +
Sbjct: 1461 INTPGSYLCSCPQDFELNPSGVGCVD---TRAGNCFLETHDRGDSGISCSAEIGVGVTRA 1517
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV--DINECHE-EGVCPS 356
C C + + TE C +G++ + DI+EC E G+C
Sbjct: 1518 SCCCSLGRAWGNPCELCP-MANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQG 1576
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRCDCP 524
G CVN GSF+C CP GY L C D DEC+ P C N G Y C CP
Sbjct: 1577 -GDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCP 1633
Score = 72.9 bits (171), Expect = 7e-13
Identities = 59/192 (30%), Positives = 84/192 (43%), Gaps = 12/192 (6%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECA-VRPPPC----DQLCHNTDGSYDC---LCRTG 167
NT+G++ CVC Y V G + C +R C + C N + +++ +C
Sbjct: 1623 NTLGNYTCVCPAEYLQ----VNGGNNCMDMRKSVCFRHYNGTCQN-ELAFNVTRKMCCCS 1677
Query: 168 YELDEDGANCRDVDECERDTHTCQQI-CSNTEGSYECSCEDGYEKRGDACVDINECHEEG 344
Y + + A R + C QI C N + G +DI+EC E
Sbjct: 1678 YNIGQ--AWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKP------LDIDECGEIP 1729
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQ--APCRNYAGGYRC 515
+ G C+N +GSFRC CP G+ ++ C D DEC ++ CQ A C N G YRC
Sbjct: 1730 AICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRC 1789
Query: 516 DCPVGTVRSPSG 551
C G SP G
Sbjct: 1790 KCTRGYKLSPGG 1801
Score = 70.5 bits (165), Expect = 4e-12
Identities = 56/185 (30%), Positives = 73/185 (39%), Gaps = 12/185 (6%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDE 182
N G FRC+C GY G +ECA P C + +C NT GSY C C +EL+
Sbjct: 1421 NLPGMFRCICNGGYELDRGGGNCTDINECA-DPVNCINGVCINTPGSYLCSCPQDFELNP 1479
Query: 183 DGANCRDV--DECERDTHTCQQICSNTEGSYECSCEDGYE-KRGDACVDINECHEEG--V 347
G C D C +TH + CS E G R C + +
Sbjct: 1480 SGVGCVDTRAGNCFLETH------DRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCEL 1533
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCV--DRDECAQT-GRCQA-PCRNYAGGYRC 515
CP +R +CP G + D DEC + G CQ C N G ++C
Sbjct: 1534 CPMANTT-----EYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQC 1588
Query: 516 DCPVG 530
+CP G
Sbjct: 1589 ECPPG 1593
Score = 59.3 bits (137), Expect = 9e-09
Identities = 58/201 (28%), Positives = 70/201 (34%), Gaps = 40/201 (19%)
Frame = +3
Query: 39 CGPGY-RPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDV-- 206
C G+ R G +EC P C C NT GS+ C C G LD G C DV
Sbjct: 855 CARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRL 914
Query: 207 DEC--ERDTHTCQQICSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCPS------ 356
+ C D C C C G + +AC D +CP
Sbjct: 915 EPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFAS 974
Query: 357 -------------------PGRCV-----NLLGSFRCVCPRGYRLDAEGARCVDRDEC-A 461
PG C N +GSF C C G+ LDA+ C D DEC
Sbjct: 975 RDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRI 1034
Query: 462 QTGRC-QAPCRNYAGGYRCDC 521
C Q C N G + C+C
Sbjct: 1035 SPDLCGQGTCVNTPGSFECEC 1055
Score = 53.6 bits (123), Expect = 4e-07
Identities = 30/80 (37%), Positives = 38/80 (47%), Gaps = 6/80 (7%)
Frame = +3
Query: 309 ACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD--RDECAQT---G 470
AC D++EC G+C G CVN++GSF C CP G+RL A C D C G
Sbjct: 244 ACQDVDECQAVPGLCQG-GSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGG 302
Query: 471 RCQAPCRNYAGGYRCDCPVG 530
RC + +C C G
Sbjct: 303 RCAGDLAGHYTRRQCCCDRG 322
Score = 52.0 bits (119), Expect = 1e-06
Identities = 26/72 (36%), Positives = 34/72 (47%)
Frame = +3
Query: 333 HEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYR 512
H +C + GRC+ S+RC C GY D G C+D DEC + C N G Y
Sbjct: 414 HFTNLCLN-GRCLPTPSSYRCECNVGYTQDVRG-ECIDVDECTSSPCHHGDCVNIPGTYH 471
Query: 513 CDCPVGTVRSPS 548
C C G +P+
Sbjct: 472 CRCYPGFQATPT 483
Score = 45.2 bits (102), Expect = 2e-04
Identities = 31/93 (33%), Positives = 42/93 (45%), Gaps = 8/93 (8%)
Frame = +3
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQ-QICSNTEGSYECSCEDGYEKRGDACVDINEC 332
CR G+ + C+DVDEC+ CQ C N GS+ C C G+ + E
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAA--CED 289
Query: 333 HEEGVCPS---PGRCV-NLLGSF---RCVCPRG 410
+ G C S GRC +L G + +C C RG
Sbjct: 290 YRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRG 322
Score = 42.7 bits (96), Expect = 8e-04
Identities = 44/147 (29%), Positives = 54/147 (36%), Gaps = 5/147 (3%)
Frame = +3
Query: 105 PPCDQLCHNTD---GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYEC 275
P CD+ CHN G C C G+ +CERD T C G C
Sbjct: 149 PICDRGCHNGGRCIGPNRCACVYGFM----------GPQCERDYRTGP--CFGQVGPEGC 196
Query: 276 SCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE 455
++ G C C G + G L + C RG+ + C D DE
Sbjct: 197 Q----HQLTGLVCTKALCCATVG--RAWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDE 250
Query: 456 C-AQTGRCQ-APCRNYAGGYRCDCPVG 530
C A G CQ C N G + C CPVG
Sbjct: 251 CQAVPGLCQGGSCVNMVGSFHCRCPVG 277
Score = 41.9 bits (94), Expect = 0.001
Identities = 43/144 (29%), Positives = 50/144 (34%), Gaps = 6/144 (4%)
Frame = +3
Query: 3 RGVNTIGS-FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELD 179
+G N GS F C PG+R GR +C V P C + C S LC
Sbjct: 55 QGPNVCGSRFHAYCCPGWRT----FPGRSQCVV--PICRRACGEGFCSQPNLCTCA---- 104
Query: 180 EDGANCRDVDECERDTHTCQQICSN--TEGSYECSCEDGYEKRGDAC---VDINECHEEG 344
DG C C N T C C+ GY G C + CH G
Sbjct: 105 -DGTLAPSCGVSRGSG--CSVSCMNGGTCRGASCLCQKGYT--GTVCGQPICDRGCHNGG 159
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYR 416
C P RC + G C R YR
Sbjct: 160 RCIGPNRCACVYGFMGPQCERDYR 183
Score = 35.1 bits (77), Expect = 0.17
Identities = 16/41 (39%), Positives = 19/41 (46%), Gaps = 1/41 (2%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRD 203
DEC P C C N GS+ C C G+ L + A C D
Sbjct: 249 DECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
>AB177800-1|BAD16736.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 184 bits (447), Expect = 2e-46
Identities = 81/177 (45%), Positives = 102/177 (57%), Gaps = 3/177 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+N++GSFRC C GY P DEC+ P PC LC NT GS+ C C GY L+E
Sbjct: 2380 INSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEE 2439
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECH-EEGVCPSP 359
DG C+D+DEC H CQ +C NT G++ C C G+ + AC D +EC + G C +
Sbjct: 2440 DGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAH 2499
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
G C N GSFRC C +G+ L + G C D +EC RCQ C+N GGYRC CP G
Sbjct: 2500 GHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGGYRCSCPQG 2556
Score = 163 bits (397), Expect = 3e-40
Identities = 78/186 (41%), Positives = 94/186 (50%), Gaps = 5/186 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELDE 182
VNT+G+F C C PG+ + DEC+ +P PC CHNT GS+ C C G+ L
Sbjct: 2462 VNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVS 2521
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPS 356
G C DV+EC+ H CQ C N G Y CSC G+ + CVD NEC
Sbjct: 2522 SGHGCEDVNECD-GPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCG 2580
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRCDCPVGT 533
C N LG FRCVCP G+ D C D DECA + G C C N GG+ C CP G
Sbjct: 2581 SASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGY 2640
Query: 534 VRSPSG 551
R+ G
Sbjct: 2641 FRAGQG 2646
Score = 159 bits (387), Expect = 5e-39
Identities = 82/189 (43%), Positives = 104/189 (55%), Gaps = 9/189 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
NT+GSF C C G+ R DEC + P C Q C NT GS++C C GYE
Sbjct: 1004 NTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGF 1063
Query: 183 D-GANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYE--KRGDACVDINECH-EEGV 347
NC DVDEC RD C C+NT+GSY+C C G+E +G AC DI+EC +G+
Sbjct: 1064 MLMKNCMDVDECARDPLLCWGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGL 1123
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQAPCRNYAGGYRCDCP 524
CP G+CVN++G+F+C C G++ + CVD +EC Q G C C N G YRC C
Sbjct: 1124 CPH-GQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCG 1182
Query: 525 VGTVRSPSG 551
G P G
Sbjct: 1183 QGYSLMPDG 1191
Score = 150 bits (364), Expect = 3e-36
Identities = 81/189 (42%), Positives = 98/189 (51%), Gaps = 10/189 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA---GRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYEL 176
VNT GSF C C PGY + DECA P C C NTDGSY C C G+EL
Sbjct: 1045 VNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCWGGTCTNTDGSYKCQCPPGHEL 1104
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECH-EEG 344
G C D+DEC C C N G+++CSC G++ D CVDINEC + G
Sbjct: 1105 TAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNG 1164
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-C-QAPCRNYAGGYRCD 518
C C+N GS+RC C +GY L +G C D DEC + R C Q C N GG+RC
Sbjct: 1165 GCDV--HCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCL 1222
Query: 519 CPVGTVRSP 545
C G + +P
Sbjct: 1223 CYDGFMATP 1231
Score = 141 bits (342), Expect = 1e-33
Identities = 75/187 (40%), Positives = 90/187 (48%), Gaps = 6/187 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELDE 182
+N GSF C C PG+ G DEC + C C N GSY C CR G+
Sbjct: 1298 LNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFA--G 1355
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCP 353
DG C D DEC + C C N G Y C CE G++ D AC D++EC + +C
Sbjct: 1356 DGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLC- 1414
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPVG 530
+ G C NL G FRC+C GY LD G C D +ECA C C N G Y C CP
Sbjct: 1415 AFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQD 1474
Query: 531 TVRSPSG 551
+PSG
Sbjct: 1475 FELNPSG 1481
Score = 140 bits (340), Expect = 2e-33
Identities = 80/189 (42%), Positives = 98/189 (51%), Gaps = 9/189 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VNT GSFRC C GY G+ DEC+V P C N G ++C C G+E
Sbjct: 2101 VNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGL 2160
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINECHE-EGVCP 353
C D+DEC + C C NTEGSY C+C GY R D C D++EC + + C
Sbjct: 2161 M-MTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCH 2219
Query: 354 SPG-RCVNLLGSFRCVCPRGYR-LDAEGARCVDRDEC-AQTGRC-QAPCRNYAGGYRCDC 521
+ G C NL+G+F CVCP G R L G C D +EC AQ C C N AG +RCDC
Sbjct: 2220 ARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDC 2279
Query: 522 PVGTVRSPS 548
G SP+
Sbjct: 2280 DEGFQPSPT 2288
Score = 138 bits (335), Expect = 9e-33
Identities = 75/184 (40%), Positives = 91/184 (49%), Gaps = 8/184 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN IG+F+C C G++ P +G +EC V+ CD C NT+GSY C C GY L
Sbjct: 1130 VNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMP 1189
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCP 353
DG C DVDECE + C Q C+N G + C C DG+ D CVD++EC
Sbjct: 1190 DGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHIC 1249
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG-RC--QAPCRNYAGGYRCDCP 524
G C N GSF C C GY + C D DEC G C A C N G + C C
Sbjct: 1250 LHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCL 1309
Query: 525 VGTV 536
G V
Sbjct: 1310 PGWV 1313
Score = 132 bits (320), Expect = 6e-31
Identities = 65/152 (42%), Positives = 77/152 (50%), Gaps = 7/152 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA-GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
N IG F C C G+ P DEC++ P C CHNT+GSY C C GY L EDG
Sbjct: 2143 NVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDG 2202
Query: 189 ANCRDVDEC---ERDTHTCQQICSNTEGSYECSCEDGYEK---RGDACVDINECHEEGVC 350
A CRDVDEC ++D H C N G++ C C G G+ C D NECH +
Sbjct: 2203 AMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDL 2262
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
GRCVN GSFRC C G++ C D
Sbjct: 2263 CVNGRCVNTAGSFRCDCDEGFQPSPTLTECHD 2294
Score = 132 bits (319), Expect = 8e-31
Identities = 75/190 (39%), Positives = 104/190 (54%), Gaps = 9/190 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGV--RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
++T GS+ C+C G++ + DEC R P + C N GSY+CLC G+ +
Sbjct: 1822 MDTEGSYMCLCHRGFQASADQTLCMDIDECD-RQPCGNGTCKNIIGSYNCLCFPGFVVTH 1880
Query: 183 DGANCRDVDECERDT-HTCQ-QICSNTEGSYECSCEDGYEKRGDA--CVDINECHE-EGV 347
+G +C D DEC C+ C NT GS+ C C+DG+E D CVD NEC G
Sbjct: 1881 NG-DCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGT 1939
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQ-APCRNYAGGYRCDC 521
C PG C NL GSFRC+CP G+++ ++ C+D DEC++ C C N G ++C C
Sbjct: 1940 C-LPGTCQNLEGSFRCICPPGFQVQSD--HCIDIDECSEEPNLCLFGTCTNSPGSFQCLC 1996
Query: 522 PVGTVRSPSG 551
P G V S +G
Sbjct: 1997 PPGFVLSDNG 2006
Score = 132 bits (318), Expect = 1e-30
Identities = 65/180 (36%), Positives = 85/180 (47%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
NT GS++C C PG+ +G D EC++ C C N G++ C C G++
Sbjct: 1089 NTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTP 1148
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPS 356
D C D++EC C C NTEGSY CSC GY G AC D++EC E
Sbjct: 1149 DRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCD 1208
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-C-QAPCRNYAGGYRCDCPVG 530
G C N+ G RC+C G+ + CVD DEC C C N G + C C +G
Sbjct: 1209 QGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLG 1268
Score = 131 bits (316), Expect = 2e-30
Identities = 70/179 (39%), Positives = 90/179 (50%), Gaps = 9/179 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRG-VRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELDE 182
N IGS+ C+C PG+ G DEC + C NT GS+ CLC+ G+EL
Sbjct: 1863 NIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTA 1922
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSP 359
DG NC D +EC TC C N EGS+ C C G++ + D C+DI+EC EE
Sbjct: 1923 DGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDIDECSEEPNLCLF 1982
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE--C---AQTGRCQAPCRNYAGGYRCDC 521
G C N GSF+C+CP G+ L G RC D + C + G+C P RC C
Sbjct: 1983 GTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCC 2041
Score = 129 bits (312), Expect = 6e-30
Identities = 64/161 (39%), Positives = 82/161 (50%), Gaps = 7/161 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNT 257
+EC V P C C NT GS+ C C G+ LD NC D+DEC C Q C NT
Sbjct: 988 NECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNT 1047
Query: 258 EGSYECSCEDGYEKRG---DACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAE 428
GS+EC C GYE C+D++EC + + G C N GS++C CP G+ L A+
Sbjct: 1048 PGSFECECFPGYESGFMLMKNCMDVDECARDPLLCWGGTCTNTDGSYKCQCPPGHELTAK 1107
Query: 429 GARCVDRDECA-QTGRC-QAPCRNYAGGYRCDCPVGTVRSP 545
G C D DEC+ G C C N G ++C C G +P
Sbjct: 1108 GTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTP 1148
Score = 127 bits (307), Expect = 2e-29
Identities = 69/156 (44%), Positives = 83/156 (53%), Gaps = 7/156 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNT 257
+ECA P C +C NTDGS+ C C GY LD G NC D DEC H C Q C+N
Sbjct: 2086 NECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVG-HPCGQGTCTNV 2144
Query: 258 EGSYECSCEDGYEK-RGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGA 434
G +EC+C DG+E C DI+EC + RC N GS+ C CP GY L +GA
Sbjct: 2145 IGGFECACADGFEPGLMMTCEDIDECSLNPLL-CAFRCHNTEGSYLCTCPAGYTLREDGA 2203
Query: 435 RCVDRDECAQTGR-CQA---PCRNYAGGYRCDCPVG 530
C D DECA + C A C+N G + C CP G
Sbjct: 2204 MCRDVDECADGQQDCHARGMECKNLIGTFACVCPPG 2239
Score = 126 bits (305), Expect = 4e-29
Identities = 67/182 (36%), Positives = 89/182 (48%), Gaps = 11/182 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD 179
VN G++ C C PG++ P + DEC V C C NT+GS+ C+C G+EL
Sbjct: 464 VNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELS 523
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINECHEEGVCP 353
DG NC D +EC T +C N +GS+ C C+ G+ G C+DI+EC G+C
Sbjct: 524 PDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICV 583
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVD---RDEC---AQTGRCQAPCRNYAGGYRC 515
+ G C N GSFRC C G + +G CVD R C + G C P C
Sbjct: 584 N-GHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSEC 642
Query: 516 DC 521
C
Sbjct: 643 CC 644
Score = 126 bits (304), Expect = 5e-29
Identities = 70/180 (38%), Positives = 82/180 (45%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELD 179
NT GSF C C GY R G DEC V CD C N GS+ C C G+
Sbjct: 1256 NTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWV-- 1313
Query: 180 EDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCP 353
DG C D+DEC H C C N GSY C+C G+ G C D +EC E
Sbjct: 1314 GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLC 1373
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ-APCRNYAGGYRCDCPVG 530
G+C+N G +RC C G+ + C D DECAQ C C N G +RC C G
Sbjct: 1374 DNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMFRCICNGG 1433
Score = 123 bits (297), Expect = 4e-28
Identities = 71/180 (39%), Positives = 90/180 (50%), Gaps = 7/180 (3%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C G GY GR V DEC + C C N+ GS+ C C+ GY D C D+D
Sbjct: 2351 CPHGSGYTAEGRDV---DECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMD 2407
Query: 210 ECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINEC-HEEGVCPSPGRCVNLL 380
EC + C +C NT+GS+ CSC GY E+ G C D++EC + C CVN +
Sbjct: 2408 ECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQF--LCVNTV 2465
Query: 381 GSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQA--PCRNYAGGYRCDCPVGTVRSPSG 551
G+F C CP G+ + C D DEC AQ G C A C N G +RC+C G SG
Sbjct: 2466 GAFTCRCPPGFTQHHQA--CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSG 2523
Score = 122 bits (295), Expect = 6e-28
Identities = 73/189 (38%), Positives = 88/189 (46%), Gaps = 6/189 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRG-VRGRDECAVRPPPCDQL-CHNTDGSYDCLCRTGYEL 176
R + T S+RC C GY RG DEC PC C N G+Y C C G++
Sbjct: 423 RCLPTPSSYRCECNVGYTQDVRGECIDVDECT--SSPCHHGDCVNIPGTYHCRCYPGFQA 480
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGV 347
C DVDEC C C NTEGS++C C G+E D CVD NEC +
Sbjct: 481 TPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTM 540
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCP 524
C + G C+N GSF C+C G+ L G C+D DEC G C C N G +RC C
Sbjct: 541 CVN-GVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCL 599
Query: 525 VGTVRSPSG 551
G G
Sbjct: 600 GGLAVGTDG 608
Score = 122 bits (294), Expect = 8e-28
Identities = 64/178 (35%), Positives = 83/178 (46%), Gaps = 4/178 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDED 185
+N GS+RC C G+ G RDECA CD C N G Y C C G++ ED
Sbjct: 1339 LNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTED 1398
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPSP 359
C+DVDEC + C N G + C C GYE + G C DINEC + C +
Sbjct: 1399 HRACQDVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCIN- 1457
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYA-GGYRCDCPVG 530
G C+N GS+ C CP+ + L+ G CVD + G C + G C +G
Sbjct: 1458 GVCINTPGSYLCSCPQDFELNPSGVGCVD----TRAGNCFLETHDRGDSGISCSAEIG 1511
Score = 122 bits (293), Expect = 1e-27
Identities = 73/184 (39%), Positives = 93/184 (50%), Gaps = 10/184 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPG--YRPAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYEL 176
+N IGSFRC C G Y DEC R PC Q C N GSY C C GY+L
Sbjct: 1738 INQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKL 1797
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGV 347
GA C +EC + C C +TEGSY C C G++ D C+DI+EC +
Sbjct: 1798 SPGGA-CVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQ-P 1855
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGR-CQ-APCRNYAGGYRCD 518
C + G C N++GS+ C+C G+ + G CVD DEC G+ C+ C N AG + C
Sbjct: 1856 CGN-GTCKNIIGSYNCLCFPGFVVTHNG-DCVDFDECTTLVGQVCRFGHCLNTAGSFHCL 1913
Query: 519 CPVG 530
C G
Sbjct: 1914 CQDG 1917
Score = 119 bits (286), Expect = 8e-27
Identities = 64/161 (39%), Positives = 82/161 (50%), Gaps = 5/161 (3%)
Frame = +3
Query: 84 DECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQI--CSN 254
DEC P C + +C N GS+ C C G+ + C DVDEC CQQ C N
Sbjct: 1723 DECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCIN 1782
Query: 255 TEGSYECSCEDGYE-KRGDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAE 428
GSY C C GY+ G ACV NEC E VC S G C++ GS+ C+C RG++ A+
Sbjct: 1783 IPGSYRCKCTRGYKLSPGGACVGRNECREIPNVC-SHGDCMDTEGSYMCLCHRGFQASAD 1841
Query: 429 GARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVRSPSG 551
C+D DEC + C+N G Y C C G V + +G
Sbjct: 1842 QTLCMDIDECDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNG 1882
Score = 109 bits (263), Expect = 5e-24
Identities = 65/175 (37%), Positives = 85/175 (48%), Gaps = 9/175 (5%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C G G GR + +ECA+ P C + +C N GSY C+C GYE G +C DVD
Sbjct: 670 CSSGLGITTDGRDI---NECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVD 726
Query: 210 ECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLL 380
EC ++ C C N+ GSY CSC G+ D C D++EC C S G C NL
Sbjct: 727 ECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP-CVS-GVCRNLA 784
Query: 381 GSFRCVCPRGYRLDAEGARCVD--RDEC---AQTGRCQAPCRNYAGGYRCDCPVG 530
GS+ C C G RLD G C+D + C Q RC+ + + C +G
Sbjct: 785 GSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLG 839
Score = 109 bits (262), Expect = 6e-24
Identities = 57/152 (37%), Positives = 71/152 (46%), Gaps = 4/152 (2%)
Frame = +3
Query: 108 PCDQLCH-NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSC 281
PC QLC + LC +G + DG RD++EC D C +C N GSY C C
Sbjct: 654 PC-QLCPAKNSAEFQALCSSGLGITTDG---RDINECALDPEVCANGVCENLRGSYRCVC 709
Query: 282 EDGYEK--RGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE 455
GYE G C D++EC + G C N GS+ C CP G+ + C D DE
Sbjct: 710 NLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDE 769
Query: 456 CAQTGRCQAPCRNYAGGYRCDCPVGTVRSPSG 551
C + CRN AG Y C C G+ PSG
Sbjct: 770 CLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSG 801
Score = 105 bits (251), Expect = 1e-22
Identities = 69/215 (32%), Positives = 96/215 (44%), Gaps = 35/215 (16%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRP---AGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELD 179
N IG+F CVC PG RP +G G +EC +P C + C NT GS+ C C G++
Sbjct: 2227 NLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPS 2286
Query: 180 EDGANCRDVDE--CERDT--HTCQQICSNTEG--SYECSCED--GYEKRGDACV------ 317
C D+ + C + C+ + S++E EC C G+ R + C
Sbjct: 2287 PTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSA 2346
Query: 318 ----------------DINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR 449
D++EC + G C+N LGSFRC C GY DA C+D
Sbjct: 2347 YRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDM 2406
Query: 450 DECAQTGR-CQAPCRNYAGGYRCDCPVGTVRSPSG 551
DEC+Q + C C+N G + C CP G + G
Sbjct: 2407 DECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDG 2441
Score = 99.1 bits (236), Expect = 9e-21
Identities = 72/219 (32%), Positives = 94/219 (42%), Gaps = 36/219 (16%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
R VNT GSF+CVC G+ P G+ +ECA + +C N DGS+ CLC+ G+ L
Sbjct: 504 RCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLL 563
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDI---NECH-- 335
G C D+DEC+ C+NTEGS+ C C G G CVD + C+
Sbjct: 564 APGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGA 623
Query: 336 -EEGVC--PSPGR-------CVN---------------LLGSFRCVCPRGYRLDAEGARC 440
E+G C P PG C N F+ +C G + +G
Sbjct: 624 IEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGR-- 681
Query: 441 VDRDECAQTGR--CQAPCRNYAGGYRCDCPVGTVRSPSG 551
D +ECA C N G YRC C +G SG
Sbjct: 682 -DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASG 719
Score = 97.5 bits (232), Expect = 3e-20
Identities = 71/209 (33%), Positives = 91/209 (43%), Gaps = 29/209 (13%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
N GS+RCVC GY +G+ DECA+ CD C N+ GSY C C G+ +
Sbjct: 700 NLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQ 759
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG--YEKRGDACVDINE--CH---EE 341
D C+DVDEC + +C N GSY C C G + G C+D + C +E
Sbjct: 760 DTEICKDVDEC-LSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQE 818
Query: 342 GVC-------PSPGRCVNLLGSF------RC----VCPRGYRLDAEGARCVDRDECAQ-T 467
C C LG+ RC C RG+ G C D +EC
Sbjct: 819 SRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGF-ARMTGVTCDDVNECESFP 877
Query: 468 GRC-QAPCRNYAGGYRCDCPVGTVRSPSG 551
G C C N AG +RC+CP G + SG
Sbjct: 878 GVCPNGRCVNTAGSFRCECPEGLMLDASG 906
Score = 88.2 bits (209), Expect = 2e-17
Identities = 73/207 (35%), Positives = 91/207 (43%), Gaps = 32/207 (15%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
N+ GS+ C C PG+ + DEC + P +C N GSY C C G LD
Sbjct: 742 NSPGSYSCSCPPGFHFWQDTEICKDVDEC-LSSPCVSGVCRNLAGSYTCKCGPGSRLDPS 800
Query: 186 GANCRD---------VDE--CERDTH--TCQQICSNTEGSY------EC----SCEDGYE 296
G C D + E CE + + + C T G+ C +C G+
Sbjct: 801 GTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFA 860
Query: 297 KR-GDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD-RDECAQT 467
+ G C D+NEC GVCP+ GRCVN GSFRC CP G LDA G CVD R E
Sbjct: 861 RMTGVTCDDVNECESFPGVCPN-GRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFL 919
Query: 468 GRCQAPCR-NYAGGYR---CDCPVGTV 536
+ C G YR C C +G V
Sbjct: 920 RWDEDECGVTLPGKYRMDVCCCSIGAV 946
Score = 87.0 bits (206), Expect = 4e-17
Identities = 39/106 (36%), Positives = 55/106 (51%), Gaps = 4/106 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDE--CAVRPPPCDQL-CHNTDGSYDCLCRTGYELDE 182
N +G +RC C G+ + + DE CA+ PP C C NT G + C+C +G++ D+
Sbjct: 2544 NQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQ 2603
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CV 317
C+DVDEC C C+NT G + C C GY + G CV
Sbjct: 2604 ALGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCV 2649
Score = 85.0 bits (201), Expect = 2e-16
Identities = 67/213 (31%), Positives = 90/213 (42%), Gaps = 37/213 (17%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPC-----DQLCHNTDGS------YD 149
R VNT GSFRC C G++P+ D +R PC +C + S +
Sbjct: 2267 RCVNTAGSFRCDCDEGFQPSPTLTECHD---IRQGPCFAEVLQTMCRSLSSSSEAVTRAE 2323
Query: 150 CLCRTG------YELDEDGANCRDVDECE---------RDTHTCQ---QICSNTE----- 260
C C G EL C RD C+ +C++ E
Sbjct: 2324 CCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSL 2383
Query: 261 GSYECSCEDGY--EKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGA 434
GS+ C C+ GY + C+D++EC + P C N GSF C CPRGY L+ +G
Sbjct: 2384 GSFRCHCQAGYTPDATATTCLDMDECSQVPK-PCTFLCKNTKGSFLCSCPRGYLLEEDGR 2442
Query: 435 RCVDRDEC-AQTGRCQAPCRNYAGGYRCDCPVG 530
C D DEC ++ CQ C N G + C CP G
Sbjct: 2443 TCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPG 2475
Score = 83.8 bits (198), Expect = 4e-16
Identities = 58/178 (32%), Positives = 76/178 (42%), Gaps = 5/178 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N+ GSF+C+C PG+ + G R D C + C + +
Sbjct: 1987 NSPGSFQCLCPPGFVLSDNGHRCFDTR-------QSFCFTRFEAGKCSVPKAFNTTKTRC 2039
Query: 192 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK---RGDACVDINECHEE-GVCPSP 359
C E C+ +++ C G+ D+ D+NEC E GVC +
Sbjct: 2040 CCSKRPG-EGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTN- 2097
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPVG 530
G CVN GSFRC CP GY LD G CVD DEC+ C Q C N GG+ C C G
Sbjct: 2098 GVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADG 2155
Score = 74.9 bits (176), Expect = 2e-13
Identities = 42/134 (31%), Positives = 57/134 (42%), Gaps = 5/134 (3%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCR--TGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECS 278
PC+ Y LC G++ + D+DEC+ CQ C NT GS++C
Sbjct: 1530 PCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCE 1589
Query: 279 CEDGYE--KRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRD 452
C GY + C DI+EC PG C N LG++ CVCP Y G C+D
Sbjct: 1590 CPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMR 1649
Query: 453 ECAQTGRCQAPCRN 494
+ C+N
Sbjct: 1650 KSVCFRHYNGTCQN 1663
Score = 72.9 bits (171), Expect = 7e-13
Identities = 54/178 (30%), Positives = 69/178 (38%), Gaps = 6/178 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNT-DGSYDCLCRTGYELDED 185
+NT GS+ C C + GV D R C H+ D C G +
Sbjct: 1461 INTPGSYLCSCPQDFELNPSGVGCVD---TRAGNCFLETHDRGDSGISCSAEIGVGVTRA 1517
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV--DINECHE-EGVCPS 356
C C + + TE C +G++ + DI+EC E G+C
Sbjct: 1518 SCCCSLGRAWGNPCELCP-MANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQG 1576
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRCDCP 524
G CVN GSF+C CP GY L C D DEC+ P C N G Y C CP
Sbjct: 1577 -GDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCP 1633
Score = 72.9 bits (171), Expect = 7e-13
Identities = 59/192 (30%), Positives = 84/192 (43%), Gaps = 12/192 (6%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECA-VRPPPC----DQLCHNTDGSYDC---LCRTG 167
NT+G++ CVC Y V G + C +R C + C N + +++ +C
Sbjct: 1623 NTLGNYTCVCPAEYLQ----VNGGNNCMDMRKSVCFRHYNGTCQN-ELAFNVTRKMCCCS 1677
Query: 168 YELDEDGANCRDVDECERDTHTCQQI-CSNTEGSYECSCEDGYEKRGDACVDINECHEEG 344
Y + + A R + C QI C N + G +DI+EC E
Sbjct: 1678 YNIGQ--AWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKP------LDIDECGEIP 1729
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQ--APCRNYAGGYRC 515
+ G C+N +GSFRC CP G+ ++ C D DEC ++ CQ A C N G YRC
Sbjct: 1730 AICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRC 1789
Query: 516 DCPVGTVRSPSG 551
C G SP G
Sbjct: 1790 KCTRGYKLSPGG 1801
Score = 70.5 bits (165), Expect = 4e-12
Identities = 56/185 (30%), Positives = 73/185 (39%), Gaps = 12/185 (6%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDE 182
N G FRC+C GY G +ECA P C + +C NT GSY C C +EL+
Sbjct: 1421 NLPGMFRCICNGGYELDRGGGNCTDINECA-DPVNCINGVCINTPGSYLCSCPQDFELNP 1479
Query: 183 DGANCRDV--DECERDTHTCQQICSNTEGSYECSCEDGYE-KRGDACVDINECHEEG--V 347
G C D C +TH + CS E G R C + +
Sbjct: 1480 SGVGCVDTRAGNCFLETH------DRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCEL 1533
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCV--DRDECAQT-GRCQA-PCRNYAGGYRC 515
CP +R +CP G + D DEC + G CQ C N G ++C
Sbjct: 1534 CPMANTT-----EYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQC 1588
Query: 516 DCPVG 530
+CP G
Sbjct: 1589 ECPPG 1593
Score = 59.3 bits (137), Expect = 9e-09
Identities = 58/201 (28%), Positives = 70/201 (34%), Gaps = 40/201 (19%)
Frame = +3
Query: 39 CGPGY-RPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDV-- 206
C G+ R G +EC P C C NT GS+ C C G LD G C DV
Sbjct: 855 CARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRL 914
Query: 207 DEC--ERDTHTCQQICSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCPS------ 356
+ C D C C C G + +AC D +CP
Sbjct: 915 EPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFAS 974
Query: 357 -------------------PGRCV-----NLLGSFRCVCPRGYRLDAEGARCVDRDEC-A 461
PG C N +GSF C C G+ LDA+ C D DEC
Sbjct: 975 RDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRI 1034
Query: 462 QTGRC-QAPCRNYAGGYRCDC 521
C Q C N G + C+C
Sbjct: 1035 SPDLCGQGTCVNTPGSFECEC 1055
Score = 53.6 bits (123), Expect = 4e-07
Identities = 30/80 (37%), Positives = 38/80 (47%), Gaps = 6/80 (7%)
Frame = +3
Query: 309 ACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD--RDECAQT---G 470
AC D++EC G+C G CVN++GSF C CP G+RL A C D C G
Sbjct: 244 ACQDVDECQAVPGLCQG-GSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGG 302
Query: 471 RCQAPCRNYAGGYRCDCPVG 530
RC + +C C G
Sbjct: 303 RCAGDLAGHYTRRQCCCDRG 322
Score = 52.0 bits (119), Expect = 1e-06
Identities = 26/72 (36%), Positives = 34/72 (47%)
Frame = +3
Query: 333 HEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYR 512
H +C + GRC+ S+RC C GY D G C+D DEC + C N G Y
Sbjct: 414 HFTNLCLN-GRCLPTPSSYRCECNVGYTQDVRG-ECIDVDECTSSPCHHGDCVNIPGTYH 471
Query: 513 CDCPVGTVRSPS 548
C C G +P+
Sbjct: 472 CRCYPGFQATPT 483
Score = 45.2 bits (102), Expect = 2e-04
Identities = 31/93 (33%), Positives = 42/93 (45%), Gaps = 8/93 (8%)
Frame = +3
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQ-QICSNTEGSYECSCEDGYEKRGDACVDINEC 332
CR G+ + C+DVDEC+ CQ C N GS+ C C G+ + E
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAA--CED 289
Query: 333 HEEGVCPS---PGRCV-NLLGSF---RCVCPRG 410
+ G C S GRC +L G + +C C RG
Sbjct: 290 YRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRG 322
Score = 42.7 bits (96), Expect = 8e-04
Identities = 44/147 (29%), Positives = 54/147 (36%), Gaps = 5/147 (3%)
Frame = +3
Query: 105 PPCDQLCHNTD---GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYEC 275
P CD+ CHN G C C G+ +CERD T C G C
Sbjct: 149 PICDRGCHNGGRCIGPNRCACVYGFM----------GPQCERDYRTGP--CFGQVGPEGC 196
Query: 276 SCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE 455
++ G C C G + G L + C RG+ + C D DE
Sbjct: 197 Q----HQLTGLVCTKALCCATVG--RAWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDE 250
Query: 456 C-AQTGRCQ-APCRNYAGGYRCDCPVG 530
C A G CQ C N G + C CPVG
Sbjct: 251 CQAVPGLCQGGSCVNMVGSFHCRCPVG 277
Score = 41.9 bits (94), Expect = 0.001
Identities = 43/144 (29%), Positives = 50/144 (34%), Gaps = 6/144 (4%)
Frame = +3
Query: 3 RGVNTIGS-FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELD 179
+G N GS F C PG+R GR +C V P C + C S LC
Sbjct: 55 QGPNVCGSRFHAYCCPGWRT----FPGRSQCVV--PICRRACGEGFCSQPNLCTCA---- 104
Query: 180 EDGANCRDVDECERDTHTCQQICSN--TEGSYECSCEDGYEKRGDAC---VDINECHEEG 344
DG C C N T C C+ GY G C + CH G
Sbjct: 105 -DGTLAPSCGVSRGSG--CSVSCMNGGTCRGASCLCQKGYT--GTVCGQPICDRGCHNGG 159
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYR 416
C P RC + G C R YR
Sbjct: 160 RCIGPNRCACVYGFMGPQCERDYR 183
Score = 35.1 bits (77), Expect = 0.17
Identities = 16/41 (39%), Positives = 19/41 (46%), Gaps = 1/41 (2%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRD 203
DEC P C C N GS+ C C G+ L + A C D
Sbjct: 249 DECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
>AB177799-1|BAD16735.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 184 bits (447), Expect = 2e-46
Identities = 81/177 (45%), Positives = 102/177 (57%), Gaps = 3/177 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+N++GSFRC C GY P DEC+ P PC LC NT GS+ C C GY L+E
Sbjct: 2380 INSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEE 2439
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECH-EEGVCPSP 359
DG C+D+DEC H CQ +C NT G++ C C G+ + AC D +EC + G C +
Sbjct: 2440 DGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAH 2499
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
G C N GSFRC C +G+ L + G C D +EC RCQ C+N GGYRC CP G
Sbjct: 2500 GHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGGYRCSCPQG 2556
Score = 163 bits (397), Expect = 3e-40
Identities = 78/186 (41%), Positives = 94/186 (50%), Gaps = 5/186 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELDE 182
VNT+G+F C C PG+ + DEC+ +P PC CHNT GS+ C C G+ L
Sbjct: 2462 VNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVS 2521
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPS 356
G C DV+EC+ H CQ C N G Y CSC G+ + CVD NEC
Sbjct: 2522 SGHGCEDVNECD-GPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCG 2580
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRCDCPVGT 533
C N LG FRCVCP G+ D C D DECA + G C C N GG+ C CP G
Sbjct: 2581 SASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGY 2640
Query: 534 VRSPSG 551
R+ G
Sbjct: 2641 FRAGQG 2646
Score = 161 bits (390), Expect = 2e-39
Identities = 82/189 (43%), Positives = 105/189 (55%), Gaps = 9/189 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
NT+GSF C C G+ R DEC + P C Q C NT GS++C C GYE
Sbjct: 1004 NTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGF 1063
Query: 183 D-GANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYE--KRGDACVDINECH-EEGV 347
NC DVDEC RD C+ C+NT+GSY+C C G+E +G AC DI+EC +G+
Sbjct: 1064 MLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGL 1123
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQAPCRNYAGGYRCDCP 524
CP G+CVN++G+F+C C G++ + CVD +EC Q G C C N G YRC C
Sbjct: 1124 CPH-GQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCG 1182
Query: 525 VGTVRSPSG 551
G P G
Sbjct: 1183 QGYSLMPDG 1191
Score = 150 bits (364), Expect = 3e-36
Identities = 81/189 (42%), Positives = 98/189 (51%), Gaps = 10/189 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA---GRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYEL 176
VNT GSF C C PGY + DECA P C C NTDGSY C C G+EL
Sbjct: 1045 VNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHEL 1104
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECH-EEG 344
G C D+DEC C C N G+++CSC G++ D CVDINEC + G
Sbjct: 1105 TAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNG 1164
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-C-QAPCRNYAGGYRCD 518
C C+N GS+RC C +GY L +G C D DEC + R C Q C N GG+RC
Sbjct: 1165 GCDV--HCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCL 1222
Query: 519 CPVGTVRSP 545
C G + +P
Sbjct: 1223 CYDGFMATP 1231
Score = 141 bits (342), Expect = 1e-33
Identities = 75/187 (40%), Positives = 90/187 (48%), Gaps = 6/187 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELDE 182
+N GSF C C PG+ G DEC + C C N GSY C CR G+
Sbjct: 1298 LNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFA--G 1355
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCP 353
DG C D DEC + C C N G Y C CE G++ D AC D++EC + +C
Sbjct: 1356 DGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLC- 1414
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPVG 530
+ G C NL G FRC+C GY LD G C D +ECA C C N G Y C CP
Sbjct: 1415 AFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQD 1474
Query: 531 TVRSPSG 551
+PSG
Sbjct: 1475 FELNPSG 1481
Score = 140 bits (340), Expect = 2e-33
Identities = 80/189 (42%), Positives = 98/189 (51%), Gaps = 9/189 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VNT GSFRC C GY G+ DEC+V P C N G ++C C G+E
Sbjct: 2101 VNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGL 2160
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINECHE-EGVCP 353
C D+DEC + C C NTEGSY C+C GY R D C D++EC + + C
Sbjct: 2161 M-MTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCH 2219
Query: 354 SPG-RCVNLLGSFRCVCPRGYR-LDAEGARCVDRDEC-AQTGRC-QAPCRNYAGGYRCDC 521
+ G C NL+G+F CVCP G R L G C D +EC AQ C C N AG +RCDC
Sbjct: 2220 ARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDC 2279
Query: 522 PVGTVRSPS 548
G SP+
Sbjct: 2280 DEGFQPSPT 2288
Score = 138 bits (335), Expect = 9e-33
Identities = 75/184 (40%), Positives = 91/184 (49%), Gaps = 8/184 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN IG+F+C C G++ P +G +EC V+ CD C NT+GSY C C GY L
Sbjct: 1130 VNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMP 1189
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCP 353
DG C DVDECE + C Q C+N G + C C DG+ D CVD++EC
Sbjct: 1190 DGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHIC 1249
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG-RC--QAPCRNYAGGYRCDCP 524
G C N GSF C C GY + C D DEC G C A C N G + C C
Sbjct: 1250 LHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCL 1309
Query: 525 VGTV 536
G V
Sbjct: 1310 PGWV 1313
Score = 132 bits (320), Expect = 6e-31
Identities = 65/152 (42%), Positives = 77/152 (50%), Gaps = 7/152 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA-GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
N IG F C C G+ P DEC++ P C CHNT+GSY C C GY L EDG
Sbjct: 2143 NVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDG 2202
Query: 189 ANCRDVDEC---ERDTHTCQQICSNTEGSYECSCEDGYEK---RGDACVDINECHEEGVC 350
A CRDVDEC ++D H C N G++ C C G G+ C D NECH +
Sbjct: 2203 AMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDL 2262
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
GRCVN GSFRC C G++ C D
Sbjct: 2263 CVNGRCVNTAGSFRCDCDEGFQPSPTLTECHD 2294
Score = 132 bits (319), Expect = 8e-31
Identities = 75/190 (39%), Positives = 104/190 (54%), Gaps = 9/190 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGV--RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
++T GS+ C+C G++ + DEC R P + C N GSY+CLC G+ +
Sbjct: 1822 MDTEGSYMCLCHRGFQASADQTLCMDIDECD-RQPCGNGTCKNIIGSYNCLCFPGFVVTH 1880
Query: 183 DGANCRDVDECERDT-HTCQ-QICSNTEGSYECSCEDGYEKRGDA--CVDINECHE-EGV 347
+G +C D DEC C+ C NT GS+ C C+DG+E D CVD NEC G
Sbjct: 1881 NG-DCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGT 1939
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQ-APCRNYAGGYRCDC 521
C PG C NL GSFRC+CP G+++ ++ C+D DEC++ C C N G ++C C
Sbjct: 1940 C-LPGTCQNLEGSFRCICPPGFQVQSD--HCIDIDECSEEPNLCLFGTCTNSPGSFQCLC 1996
Query: 522 PVGTVRSPSG 551
P G V S +G
Sbjct: 1997 PPGFVLSDNG 2006
Score = 132 bits (318), Expect = 1e-30
Identities = 65/180 (36%), Positives = 85/180 (47%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
NT GS++C C PG+ +G D EC++ C C N G++ C C G++
Sbjct: 1089 NTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTP 1148
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPS 356
D C D++EC C C NTEGSY CSC GY G AC D++EC E
Sbjct: 1149 DRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCD 1208
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-C-QAPCRNYAGGYRCDCPVG 530
G C N+ G RC+C G+ + CVD DEC C C N G + C C +G
Sbjct: 1209 QGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLG 1268
Score = 131 bits (316), Expect = 2e-30
Identities = 70/179 (39%), Positives = 90/179 (50%), Gaps = 9/179 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRG-VRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELDE 182
N IGS+ C+C PG+ G DEC + C NT GS+ CLC+ G+EL
Sbjct: 1863 NIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTA 1922
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSP 359
DG NC D +EC TC C N EGS+ C C G++ + D C+DI+EC EE
Sbjct: 1923 DGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDIDECSEEPNLCLF 1982
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE--C---AQTGRCQAPCRNYAGGYRCDC 521
G C N GSF+C+CP G+ L G RC D + C + G+C P RC C
Sbjct: 1983 GTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCC 2041
Score = 130 bits (314), Expect = 3e-30
Identities = 64/161 (39%), Positives = 82/161 (50%), Gaps = 7/161 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNT 257
+EC V P C C NT GS+ C C G+ LD NC D+DEC C Q C NT
Sbjct: 988 NECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNT 1047
Query: 258 EGSYECSCEDGYEKRG---DACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAE 428
GS+EC C GYE C+D++EC + + G C N GS++C CP G+ L A+
Sbjct: 1048 PGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAK 1107
Query: 429 GARCVDRDECA-QTGRC-QAPCRNYAGGYRCDCPVGTVRSP 545
G C D DEC+ G C C N G ++C C G +P
Sbjct: 1108 GTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTP 1148
Score = 127 bits (307), Expect = 2e-29
Identities = 69/156 (44%), Positives = 83/156 (53%), Gaps = 7/156 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNT 257
+ECA P C +C NTDGS+ C C GY LD G NC D DEC H C Q C+N
Sbjct: 2086 NECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVG-HPCGQGTCTNV 2144
Query: 258 EGSYECSCEDGYEK-RGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGA 434
G +EC+C DG+E C DI+EC + RC N GS+ C CP GY L +GA
Sbjct: 2145 IGGFECACADGFEPGLMMTCEDIDECSLNPLL-CAFRCHNTEGSYLCTCPAGYTLREDGA 2203
Query: 435 RCVDRDECAQTGR-CQA---PCRNYAGGYRCDCPVG 530
C D DECA + C A C+N G + C CP G
Sbjct: 2204 MCRDVDECADGQQDCHARGMECKNLIGTFACVCPPG 2239
Score = 126 bits (305), Expect = 4e-29
Identities = 67/182 (36%), Positives = 89/182 (48%), Gaps = 11/182 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD 179
VN G++ C C PG++ P + DEC V C C NT+GS+ C+C G+EL
Sbjct: 464 VNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELS 523
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINECHEEGVCP 353
DG NC D +EC T +C N +GS+ C C+ G+ G C+DI+EC G+C
Sbjct: 524 PDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICV 583
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVD---RDEC---AQTGRCQAPCRNYAGGYRC 515
+ G C N GSFRC C G + +G CVD R C + G C P C
Sbjct: 584 N-GHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSEC 642
Query: 516 DC 521
C
Sbjct: 643 CC 644
Score = 126 bits (304), Expect = 5e-29
Identities = 70/180 (38%), Positives = 82/180 (45%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELD 179
NT GSF C C GY R G DEC V CD C N GS+ C C G+
Sbjct: 1256 NTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWV-- 1313
Query: 180 EDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCP 353
DG C D+DEC H C C N GSY C+C G+ G C D +EC E
Sbjct: 1314 GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLC 1373
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ-APCRNYAGGYRCDCPVG 530
G+C+N G +RC C G+ + C D DECAQ C C N G +RC C G
Sbjct: 1374 DNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMFRCICNGG 1433
Score = 123 bits (297), Expect = 4e-28
Identities = 71/180 (39%), Positives = 90/180 (50%), Gaps = 7/180 (3%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C G GY GR V DEC + C C N+ GS+ C C+ GY D C D+D
Sbjct: 2351 CPHGSGYTAEGRDV---DECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMD 2407
Query: 210 ECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINEC-HEEGVCPSPGRCVNLL 380
EC + C +C NT+GS+ CSC GY E+ G C D++EC + C CVN +
Sbjct: 2408 ECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQF--LCVNTV 2465
Query: 381 GSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQA--PCRNYAGGYRCDCPVGTVRSPSG 551
G+F C CP G+ + C D DEC AQ G C A C N G +RC+C G SG
Sbjct: 2466 GAFTCRCPPGFTQHHQA--CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSG 2523
Score = 122 bits (295), Expect = 6e-28
Identities = 73/189 (38%), Positives = 88/189 (46%), Gaps = 6/189 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRG-VRGRDECAVRPPPCDQL-CHNTDGSYDCLCRTGYEL 176
R + T S+RC C GY RG DEC PC C N G+Y C C G++
Sbjct: 423 RCLPTPSSYRCECNVGYTQDVRGECIDVDECT--SSPCHHGDCVNIPGTYHCRCYPGFQA 480
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGV 347
C DVDEC C C NTEGS++C C G+E D CVD NEC +
Sbjct: 481 TPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTM 540
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCP 524
C + G C+N GSF C+C G+ L G C+D DEC G C C N G +RC C
Sbjct: 541 CVN-GVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCL 599
Query: 525 VGTVRSPSG 551
G G
Sbjct: 600 GGLAVGTDG 608
Score = 122 bits (294), Expect = 8e-28
Identities = 64/178 (35%), Positives = 83/178 (46%), Gaps = 4/178 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDED 185
+N GS+RC C G+ G RDECA CD C N G Y C C G++ ED
Sbjct: 1339 LNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTED 1398
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPSP 359
C+DVDEC + C N G + C C GYE + G C DINEC + C +
Sbjct: 1399 HRACQDVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCIN- 1457
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYA-GGYRCDCPVG 530
G C+N GS+ C CP+ + L+ G CVD + G C + G C +G
Sbjct: 1458 GVCINTPGSYLCSCPQDFELNPSGVGCVD----TRAGNCFLETHDRGDSGISCSAEIG 1511
Score = 122 bits (293), Expect = 1e-27
Identities = 73/184 (39%), Positives = 93/184 (50%), Gaps = 10/184 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPG--YRPAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYEL 176
+N IGSFRC C G Y DEC R PC Q C N GSY C C GY+L
Sbjct: 1738 INQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKL 1797
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGV 347
GA C +EC + C C +TEGSY C C G++ D C+DI+EC +
Sbjct: 1798 SPGGA-CVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQ-P 1855
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGR-CQ-APCRNYAGGYRCD 518
C + G C N++GS+ C+C G+ + G CVD DEC G+ C+ C N AG + C
Sbjct: 1856 CGN-GTCKNIIGSYNCLCFPGFVVTHNG-DCVDFDECTTLVGQVCRFGHCLNTAGSFHCL 1913
Query: 519 CPVG 530
C G
Sbjct: 1914 CQDG 1917
Score = 119 bits (286), Expect = 8e-27
Identities = 64/161 (39%), Positives = 82/161 (50%), Gaps = 5/161 (3%)
Frame = +3
Query: 84 DECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQI--CSN 254
DEC P C + +C N GS+ C C G+ + C DVDEC CQQ C N
Sbjct: 1723 DECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCIN 1782
Query: 255 TEGSYECSCEDGYE-KRGDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAE 428
GSY C C GY+ G ACV NEC E VC S G C++ GS+ C+C RG++ A+
Sbjct: 1783 IPGSYRCKCTRGYKLSPGGACVGRNECREIPNVC-SHGDCMDTEGSYMCLCHRGFQASAD 1841
Query: 429 GARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVRSPSG 551
C+D DEC + C+N G Y C C G V + +G
Sbjct: 1842 QTLCMDIDECDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNG 1882
Score = 109 bits (263), Expect = 5e-24
Identities = 65/175 (37%), Positives = 85/175 (48%), Gaps = 9/175 (5%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C G G GR + +ECA+ P C + +C N GSY C+C GYE G +C DVD
Sbjct: 670 CSSGLGITTDGRDI---NECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVD 726
Query: 210 ECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLL 380
EC ++ C C N+ GSY CSC G+ D C D++EC C S G C NL
Sbjct: 727 ECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP-CVS-GVCRNLA 784
Query: 381 GSFRCVCPRGYRLDAEGARCVD--RDEC---AQTGRCQAPCRNYAGGYRCDCPVG 530
GS+ C C G RLD G C+D + C Q RC+ + + C +G
Sbjct: 785 GSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLG 839
Score = 109 bits (262), Expect = 6e-24
Identities = 57/152 (37%), Positives = 71/152 (46%), Gaps = 4/152 (2%)
Frame = +3
Query: 108 PCDQLCH-NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSC 281
PC QLC + LC +G + DG RD++EC D C +C N GSY C C
Sbjct: 654 PC-QLCPAKNSAEFQALCSSGLGITTDG---RDINECALDPEVCANGVCENLRGSYRCVC 709
Query: 282 EDGYEK--RGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE 455
GYE G C D++EC + G C N GS+ C CP G+ + C D DE
Sbjct: 710 NLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDE 769
Query: 456 CAQTGRCQAPCRNYAGGYRCDCPVGTVRSPSG 551
C + CRN AG Y C C G+ PSG
Sbjct: 770 CLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSG 801
Score = 105 bits (251), Expect = 1e-22
Identities = 69/215 (32%), Positives = 96/215 (44%), Gaps = 35/215 (16%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRP---AGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELD 179
N IG+F CVC PG RP +G G +EC +P C + C NT GS+ C C G++
Sbjct: 2227 NLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPS 2286
Query: 180 EDGANCRDVDE--CERDT--HTCQQICSNTEG--SYECSCED--GYEKRGDACV------ 317
C D+ + C + C+ + S++E EC C G+ R + C
Sbjct: 2287 PTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSA 2346
Query: 318 ----------------DINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR 449
D++EC + G C+N LGSFRC C GY DA C+D
Sbjct: 2347 YRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDM 2406
Query: 450 DECAQTGR-CQAPCRNYAGGYRCDCPVGTVRSPSG 551
DEC+Q + C C+N G + C CP G + G
Sbjct: 2407 DECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDG 2441
Score = 99.1 bits (236), Expect = 9e-21
Identities = 72/219 (32%), Positives = 94/219 (42%), Gaps = 36/219 (16%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
R VNT GSF+CVC G+ P G+ +ECA + +C N DGS+ CLC+ G+ L
Sbjct: 504 RCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLL 563
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDI---NECH-- 335
G C D+DEC+ C+NTEGS+ C C G G CVD + C+
Sbjct: 564 APGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGA 623
Query: 336 -EEGVC--PSPGR-------CVN---------------LLGSFRCVCPRGYRLDAEGARC 440
E+G C P PG C N F+ +C G + +G
Sbjct: 624 IEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGR-- 681
Query: 441 VDRDECAQTGR--CQAPCRNYAGGYRCDCPVGTVRSPSG 551
D +ECA C N G YRC C +G SG
Sbjct: 682 -DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASG 719
Score = 97.5 bits (232), Expect = 3e-20
Identities = 71/209 (33%), Positives = 91/209 (43%), Gaps = 29/209 (13%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
N GS+RCVC GY +G+ DECA+ CD C N+ GSY C C G+ +
Sbjct: 700 NLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQ 759
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG--YEKRGDACVDINE--CH---EE 341
D C+DVDEC + +C N GSY C C G + G C+D + C +E
Sbjct: 760 DTEICKDVDEC-LSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQE 818
Query: 342 GVC-------PSPGRCVNLLGSF------RC----VCPRGYRLDAEGARCVDRDECAQ-T 467
C C LG+ RC C RG+ G C D +EC
Sbjct: 819 SRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGF-ARMTGVTCDDVNECESFP 877
Query: 468 GRC-QAPCRNYAGGYRCDCPVGTVRSPSG 551
G C C N AG +RC+CP G + SG
Sbjct: 878 GVCPNGRCVNTAGSFRCECPEGLMLDASG 906
Score = 88.2 bits (209), Expect = 2e-17
Identities = 73/207 (35%), Positives = 91/207 (43%), Gaps = 32/207 (15%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
N+ GS+ C C PG+ + DEC + P +C N GSY C C G LD
Sbjct: 742 NSPGSYSCSCPPGFHFWQDTEICKDVDEC-LSSPCVSGVCRNLAGSYTCKCGPGSRLDPS 800
Query: 186 GANCRD---------VDE--CERDTH--TCQQICSNTEGSY------EC----SCEDGYE 296
G C D + E CE + + + C T G+ C +C G+
Sbjct: 801 GTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFA 860
Query: 297 KR-GDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD-RDECAQT 467
+ G C D+NEC GVCP+ GRCVN GSFRC CP G LDA G CVD R E
Sbjct: 861 RMTGVTCDDVNECESFPGVCPN-GRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFL 919
Query: 468 GRCQAPCR-NYAGGYR---CDCPVGTV 536
+ C G YR C C +G V
Sbjct: 920 RWDEDECGVTLPGKYRMDFCCCSIGAV 946
Score = 87.0 bits (206), Expect = 4e-17
Identities = 39/106 (36%), Positives = 55/106 (51%), Gaps = 4/106 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDE--CAVRPPPCDQL-CHNTDGSYDCLCRTGYELDE 182
N +G +RC C G+ + + DE CA+ PP C C NT G + C+C +G++ D+
Sbjct: 2544 NQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQ 2603
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CV 317
C+DVDEC C C+NT G + C C GY + G CV
Sbjct: 2604 ALGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCV 2649
Score = 85.0 bits (201), Expect = 2e-16
Identities = 67/213 (31%), Positives = 90/213 (42%), Gaps = 37/213 (17%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPC-----DQLCHNTDGS------YD 149
R VNT GSFRC C G++P+ D +R PC +C + S +
Sbjct: 2267 RCVNTAGSFRCDCDEGFQPSPTLTECHD---IRQGPCFAEVLQTMCRSLSSSSEAVTRAE 2323
Query: 150 CLCRTG------YELDEDGANCRDVDECE---------RDTHTCQ---QICSNTE----- 260
C C G EL C RD C+ +C++ E
Sbjct: 2324 CCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSL 2383
Query: 261 GSYECSCEDGY--EKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGA 434
GS+ C C+ GY + C+D++EC + P C N GSF C CPRGY L+ +G
Sbjct: 2384 GSFRCHCQAGYTPDATATTCLDMDECSQVPK-PCTFLCKNTKGSFLCSCPRGYLLEEDGR 2442
Query: 435 RCVDRDEC-AQTGRCQAPCRNYAGGYRCDCPVG 530
C D DEC ++ CQ C N G + C CP G
Sbjct: 2443 TCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPG 2475
Score = 83.8 bits (198), Expect = 4e-16
Identities = 58/178 (32%), Positives = 76/178 (42%), Gaps = 5/178 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N+ GSF+C+C PG+ + G R D C + C + +
Sbjct: 1987 NSPGSFQCLCPPGFVLSDNGHRCFDTR-------QSFCFTRFEAGKCSVPKAFNTTKTRC 2039
Query: 192 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK---RGDACVDINECHEE-GVCPSP 359
C E C+ +++ C G+ D+ D+NEC E GVC +
Sbjct: 2040 CCSKRPG-EGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTN- 2097
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPVG 530
G CVN GSFRC CP GY LD G CVD DEC+ C Q C N GG+ C C G
Sbjct: 2098 GVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADG 2155
Score = 74.9 bits (176), Expect = 2e-13
Identities = 42/134 (31%), Positives = 57/134 (42%), Gaps = 5/134 (3%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCR--TGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECS 278
PC+ Y LC G++ + D+DEC+ CQ C NT GS++C
Sbjct: 1530 PCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCE 1589
Query: 279 CEDGYE--KRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRD 452
C GY + C DI+EC PG C N LG++ CVCP Y G C+D
Sbjct: 1590 CPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMR 1649
Query: 453 ECAQTGRCQAPCRN 494
+ C+N
Sbjct: 1650 KSVCFRHYNGTCQN 1663
Score = 72.9 bits (171), Expect = 7e-13
Identities = 54/178 (30%), Positives = 69/178 (38%), Gaps = 6/178 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNT-DGSYDCLCRTGYELDED 185
+NT GS+ C C + GV D R C H+ D C G +
Sbjct: 1461 INTPGSYLCSCPQDFELNPSGVGCVD---TRAGNCFLETHDRGDSGISCSAEIGVGVTRA 1517
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV--DINECHE-EGVCPS 356
C C + + TE C +G++ + DI+EC E G+C
Sbjct: 1518 SCCCSLGRAWGNPCELCP-MANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQG 1576
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRCDCP 524
G CVN GSF+C CP GY L C D DEC+ P C N G Y C CP
Sbjct: 1577 -GDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCP 1633
Score = 72.9 bits (171), Expect = 7e-13
Identities = 59/192 (30%), Positives = 84/192 (43%), Gaps = 12/192 (6%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECA-VRPPPC----DQLCHNTDGSYDC---LCRTG 167
NT+G++ CVC Y V G + C +R C + C N + +++ +C
Sbjct: 1623 NTLGNYTCVCPAEYLQ----VNGGNNCMDMRKSVCFRHYNGTCQN-ELAFNVTRKMCCCS 1677
Query: 168 YELDEDGANCRDVDECERDTHTCQQI-CSNTEGSYECSCEDGYEKRGDACVDINECHEEG 344
Y + + A R + C QI C N + G +DI+EC E
Sbjct: 1678 YNIGQ--AWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKP------LDIDECGEIP 1729
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQ--APCRNYAGGYRC 515
+ G C+N +GSFRC CP G+ ++ C D DEC ++ CQ A C N G YRC
Sbjct: 1730 AICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRC 1789
Query: 516 DCPVGTVRSPSG 551
C G SP G
Sbjct: 1790 KCTRGYKLSPGG 1801
Score = 70.5 bits (165), Expect = 4e-12
Identities = 56/185 (30%), Positives = 73/185 (39%), Gaps = 12/185 (6%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDE 182
N G FRC+C GY G +ECA P C + +C NT GSY C C +EL+
Sbjct: 1421 NLPGMFRCICNGGYELDRGGGNCTDINECA-DPVNCINGVCINTPGSYLCSCPQDFELNP 1479
Query: 183 DGANCRDV--DECERDTHTCQQICSNTEGSYECSCEDGYE-KRGDACVDINECHEEG--V 347
G C D C +TH + CS E G R C + +
Sbjct: 1480 SGVGCVDTRAGNCFLETH------DRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCEL 1533
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCV--DRDECAQT-GRCQA-PCRNYAGGYRC 515
CP +R +CP G + D DEC + G CQ C N G ++C
Sbjct: 1534 CPMANTT-----EYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQC 1588
Query: 516 DCPVG 530
+CP G
Sbjct: 1589 ECPPG 1593
Score = 58.8 bits (136), Expect = 1e-08
Identities = 58/201 (28%), Positives = 70/201 (34%), Gaps = 40/201 (19%)
Frame = +3
Query: 39 CGPGY-RPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDV-- 206
C G+ R G +EC P C C NT GS+ C C G LD G C DV
Sbjct: 855 CARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRL 914
Query: 207 DEC--ERDTHTCQQICSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCPS------ 356
+ C D C C C G + +AC D +CP
Sbjct: 915 EPCFLRWDEDECGVTLPGKYRMDFCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFAS 974
Query: 357 -------------------PGRCV-----NLLGSFRCVCPRGYRLDAEGARCVDRDEC-A 461
PG C N +GSF C C G+ LDA+ C D DEC
Sbjct: 975 RDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRI 1034
Query: 462 QTGRC-QAPCRNYAGGYRCDC 521
C Q C N G + C+C
Sbjct: 1035 SPDLCGQGTCVNTPGSFECEC 1055
Score = 53.6 bits (123), Expect = 4e-07
Identities = 30/80 (37%), Positives = 38/80 (47%), Gaps = 6/80 (7%)
Frame = +3
Query: 309 ACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD--RDECAQT---G 470
AC D++EC G+C G CVN++GSF C CP G+RL A C D C G
Sbjct: 244 ACQDVDECQAVPGLCQG-GSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGG 302
Query: 471 RCQAPCRNYAGGYRCDCPVG 530
RC + +C C G
Sbjct: 303 RCAGDLAGHYTRRQCCCDRG 322
Score = 52.0 bits (119), Expect = 1e-06
Identities = 26/72 (36%), Positives = 34/72 (47%)
Frame = +3
Query: 333 HEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYR 512
H +C + GRC+ S+RC C GY D G C+D DEC + C N G Y
Sbjct: 414 HFTNLCLN-GRCLPTPSSYRCECNVGYTQDVRG-ECIDVDECTSSPCHHGDCVNIPGTYH 471
Query: 513 CDCPVGTVRSPS 548
C C G +P+
Sbjct: 472 CRCYPGFQATPT 483
Score = 45.2 bits (102), Expect = 2e-04
Identities = 31/93 (33%), Positives = 42/93 (45%), Gaps = 8/93 (8%)
Frame = +3
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQ-QICSNTEGSYECSCEDGYEKRGDACVDINEC 332
CR G+ + C+DVDEC+ CQ C N GS+ C C G+ + E
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAA--CED 289
Query: 333 HEEGVCPS---PGRCV-NLLGSF---RCVCPRG 410
+ G C S GRC +L G + +C C RG
Sbjct: 290 YRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRG 322
Score = 42.7 bits (96), Expect = 8e-04
Identities = 44/147 (29%), Positives = 54/147 (36%), Gaps = 5/147 (3%)
Frame = +3
Query: 105 PPCDQLCHNTD---GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYEC 275
P CD+ CHN G C C G+ +CERD T C G C
Sbjct: 149 PICDRGCHNGGRCIGPNRCACVYGFM----------GPQCERDYRTGP--CFGQVGPEGC 196
Query: 276 SCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE 455
++ G C C G + G L + C RG+ + C D DE
Sbjct: 197 Q----HQLTGLVCTKALCCATVG--RAWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDE 250
Query: 456 C-AQTGRCQ-APCRNYAGGYRCDCPVG 530
C A G CQ C N G + C CPVG
Sbjct: 251 CQAVPGLCQGGSCVNMVGSFHCRCPVG 277
Score = 41.9 bits (94), Expect = 0.001
Identities = 43/144 (29%), Positives = 50/144 (34%), Gaps = 6/144 (4%)
Frame = +3
Query: 3 RGVNTIGS-FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELD 179
+G N GS F C PG+R GR +C V P C + C S LC
Sbjct: 55 QGPNVCGSRFHAYCCPGWRT----FPGRSQCVV--PICRRACGEGFCSQPNLCTCA---- 104
Query: 180 EDGANCRDVDECERDTHTCQQICSN--TEGSYECSCEDGYEKRGDAC---VDINECHEEG 344
DG C C N T C C+ GY G C + CH G
Sbjct: 105 -DGTLAPSCGVSRGSG--CSVSCMNGGTCRGASCLCQKGYT--GTVCGQPICDRGCHNGG 159
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYR 416
C P RC + G C R YR
Sbjct: 160 RCIGPNRCACVYGFMGPQCERDYR 183
Score = 35.1 bits (77), Expect = 0.17
Identities = 16/41 (39%), Positives = 19/41 (46%), Gaps = 1/41 (2%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRD 203
DEC P C C N GS+ C C G+ L + A C D
Sbjct: 249 DECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
>AB177798-1|BAD16734.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 184 bits (447), Expect = 2e-46
Identities = 81/177 (45%), Positives = 102/177 (57%), Gaps = 3/177 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+N++GSFRC C GY P DEC+ P PC LC NT GS+ C C GY L+E
Sbjct: 2380 INSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEE 2439
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECH-EEGVCPSP 359
DG C+D+DEC H CQ +C NT G++ C C G+ + AC D +EC + G C +
Sbjct: 2440 DGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAH 2499
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
G C N GSFRC C +G+ L + G C D +EC RCQ C+N GGYRC CP G
Sbjct: 2500 GHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGGYRCSCPQG 2556
Score = 163 bits (397), Expect = 3e-40
Identities = 78/186 (41%), Positives = 94/186 (50%), Gaps = 5/186 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELDE 182
VNT+G+F C C PG+ + DEC+ +P PC CHNT GS+ C C G+ L
Sbjct: 2462 VNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVS 2521
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPS 356
G C DV+EC+ H CQ C N G Y CSC G+ + CVD NEC
Sbjct: 2522 SGHGCEDVNECD-GPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCG 2580
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRCDCPVGT 533
C N LG FRCVCP G+ D C D DECA + G C C N GG+ C CP G
Sbjct: 2581 SASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGY 2640
Query: 534 VRSPSG 551
R+ G
Sbjct: 2641 FRAGQG 2646
Score = 161 bits (390), Expect = 2e-39
Identities = 82/189 (43%), Positives = 105/189 (55%), Gaps = 9/189 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
NT+GSF C C G+ R DEC + P C Q C NT GS++C C GYE
Sbjct: 1004 NTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGF 1063
Query: 183 D-GANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYE--KRGDACVDINECH-EEGV 347
NC DVDEC RD C+ C+NT+GSY+C C G+E +G AC DI+EC +G+
Sbjct: 1064 MLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGL 1123
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQAPCRNYAGGYRCDCP 524
CP G+CVN++G+F+C C G++ + CVD +EC Q G C C N G YRC C
Sbjct: 1124 CPH-GQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCG 1182
Query: 525 VGTVRSPSG 551
G P G
Sbjct: 1183 QGYSLMPDG 1191
Score = 150 bits (364), Expect = 3e-36
Identities = 81/189 (42%), Positives = 98/189 (51%), Gaps = 10/189 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA---GRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYEL 176
VNT GSF C C PGY + DECA P C C NTDGSY C C G+EL
Sbjct: 1045 VNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHEL 1104
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECH-EEG 344
G C D+DEC C C N G+++CSC G++ D CVDINEC + G
Sbjct: 1105 TAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNG 1164
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-C-QAPCRNYAGGYRCD 518
C C+N GS+RC C +GY L +G C D DEC + R C Q C N GG+RC
Sbjct: 1165 GCDV--HCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCL 1222
Query: 519 CPVGTVRSP 545
C G + +P
Sbjct: 1223 CYDGFMATP 1231
Score = 141 bits (342), Expect = 1e-33
Identities = 75/187 (40%), Positives = 90/187 (48%), Gaps = 6/187 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELDE 182
+N GSF C C PG+ G DEC + C C N GSY C CR G+
Sbjct: 1298 LNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFA--G 1355
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCP 353
DG C D DEC + C C N G Y C CE G++ D AC D++EC + +C
Sbjct: 1356 DGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLC- 1414
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPVG 530
+ G C NL G FRC+C GY LD G C D +ECA C C N G Y C CP
Sbjct: 1415 AFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQD 1474
Query: 531 TVRSPSG 551
+PSG
Sbjct: 1475 FELNPSG 1481
Score = 140 bits (340), Expect = 2e-33
Identities = 80/189 (42%), Positives = 98/189 (51%), Gaps = 9/189 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VNT GSFRC C GY G+ DEC+V P C N G ++C C G+E
Sbjct: 2101 VNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGL 2160
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINECHE-EGVCP 353
C D+DEC + C C NTEGSY C+C GY R D C D++EC + + C
Sbjct: 2161 M-MTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCH 2219
Query: 354 SPG-RCVNLLGSFRCVCPRGYR-LDAEGARCVDRDEC-AQTGRC-QAPCRNYAGGYRCDC 521
+ G C NL+G+F CVCP G R L G C D +EC AQ C C N AG +RCDC
Sbjct: 2220 ARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDC 2279
Query: 522 PVGTVRSPS 548
G SP+
Sbjct: 2280 DEGFQPSPT 2288
Score = 138 bits (335), Expect = 9e-33
Identities = 75/184 (40%), Positives = 91/184 (49%), Gaps = 8/184 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN IG+F+C C G++ P +G +EC V+ CD C NT+GSY C C GY L
Sbjct: 1130 VNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMP 1189
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCP 353
DG C DVDECE + C Q C+N G + C C DG+ D CVD++EC
Sbjct: 1190 DGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHIC 1249
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG-RC--QAPCRNYAGGYRCDCP 524
G C N GSF C C GY + C D DEC G C A C N G + C C
Sbjct: 1250 LHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCL 1309
Query: 525 VGTV 536
G V
Sbjct: 1310 PGWV 1313
Score = 132 bits (320), Expect = 6e-31
Identities = 65/152 (42%), Positives = 77/152 (50%), Gaps = 7/152 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA-GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
N IG F C C G+ P DEC++ P C CHNT+GSY C C GY L EDG
Sbjct: 2143 NVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDG 2202
Query: 189 ANCRDVDEC---ERDTHTCQQICSNTEGSYECSCEDGYEK---RGDACVDINECHEEGVC 350
A CRDVDEC ++D H C N G++ C C G G+ C D NECH +
Sbjct: 2203 AMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDL 2262
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
GRCVN GSFRC C G++ C D
Sbjct: 2263 CVNGRCVNTAGSFRCDCDEGFQPSPTLTECHD 2294
Score = 132 bits (319), Expect = 8e-31
Identities = 75/190 (39%), Positives = 104/190 (54%), Gaps = 9/190 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGV--RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
++T GS+ C+C G++ + DEC R P + C N GSY+CLC G+ +
Sbjct: 1822 MDTEGSYMCLCHRGFQASADQTLCMDIDECD-RQPCGNGTCKNIIGSYNCLCFPGFVVTH 1880
Query: 183 DGANCRDVDECERDT-HTCQ-QICSNTEGSYECSCEDGYEKRGDA--CVDINECHE-EGV 347
+G +C D DEC C+ C NT GS+ C C+DG+E D CVD NEC G
Sbjct: 1881 NG-DCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGT 1939
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQ-APCRNYAGGYRCDC 521
C PG C NL GSFRC+CP G+++ ++ C+D DEC++ C C N G ++C C
Sbjct: 1940 C-LPGTCQNLEGSFRCICPPGFQVQSD--HCIDIDECSEEPNLCLFGTCTNSPGSFQCLC 1996
Query: 522 PVGTVRSPSG 551
P G V S +G
Sbjct: 1997 PPGFVLSDNG 2006
Score = 132 bits (318), Expect = 1e-30
Identities = 65/180 (36%), Positives = 85/180 (47%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
NT GS++C C PG+ +G D EC++ C C N G++ C C G++
Sbjct: 1089 NTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTP 1148
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPS 356
D C D++EC C C NTEGSY CSC GY G AC D++EC E
Sbjct: 1149 DRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCD 1208
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-C-QAPCRNYAGGYRCDCPVG 530
G C N+ G RC+C G+ + CVD DEC C C N G + C C +G
Sbjct: 1209 QGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLG 1268
Score = 131 bits (316), Expect = 2e-30
Identities = 70/179 (39%), Positives = 90/179 (50%), Gaps = 9/179 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRG-VRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELDE 182
N IGS+ C+C PG+ G DEC + C NT GS+ CLC+ G+EL
Sbjct: 1863 NIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTA 1922
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSP 359
DG NC D +EC TC C N EGS+ C C G++ + D C+DI+EC EE
Sbjct: 1923 DGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDIDECSEEPNLCLF 1982
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE--C---AQTGRCQAPCRNYAGGYRCDC 521
G C N GSF+C+CP G+ L G RC D + C + G+C P RC C
Sbjct: 1983 GTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCC 2041
Score = 130 bits (314), Expect = 3e-30
Identities = 64/161 (39%), Positives = 82/161 (50%), Gaps = 7/161 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNT 257
+EC V P C C NT GS+ C C G+ LD NC D+DEC C Q C NT
Sbjct: 988 NECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNT 1047
Query: 258 EGSYECSCEDGYEKRG---DACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAE 428
GS+EC C GYE C+D++EC + + G C N GS++C CP G+ L A+
Sbjct: 1048 PGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAK 1107
Query: 429 GARCVDRDECA-QTGRC-QAPCRNYAGGYRCDCPVGTVRSP 545
G C D DEC+ G C C N G ++C C G +P
Sbjct: 1108 GTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTP 1148
Score = 127 bits (307), Expect = 2e-29
Identities = 69/156 (44%), Positives = 83/156 (53%), Gaps = 7/156 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNT 257
+ECA P C +C NTDGS+ C C GY LD G NC D DEC H C Q C+N
Sbjct: 2086 NECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVG-HPCGQGTCTNV 2144
Query: 258 EGSYECSCEDGYEK-RGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGA 434
G +EC+C DG+E C DI+EC + RC N GS+ C CP GY L +GA
Sbjct: 2145 IGGFECACADGFEPGLMMTCEDIDECSLNPLL-CAFRCHNTEGSYLCTCPAGYTLREDGA 2203
Query: 435 RCVDRDECAQTGR-CQA---PCRNYAGGYRCDCPVG 530
C D DECA + C A C+N G + C CP G
Sbjct: 2204 MCRDVDECADGQQDCHARGMECKNLIGTFACVCPPG 2239
Score = 126 bits (305), Expect = 4e-29
Identities = 67/182 (36%), Positives = 89/182 (48%), Gaps = 11/182 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD 179
VN G++ C C PG++ P + DEC V C C NT+GS+ C+C G+EL
Sbjct: 464 VNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELS 523
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINECHEEGVCP 353
DG NC D +EC T +C N +GS+ C C+ G+ G C+DI+EC G+C
Sbjct: 524 PDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICV 583
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVD---RDEC---AQTGRCQAPCRNYAGGYRC 515
+ G C N GSFRC C G + +G CVD R C + G C P C
Sbjct: 584 N-GHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSEC 642
Query: 516 DC 521
C
Sbjct: 643 CC 644
Score = 126 bits (304), Expect = 5e-29
Identities = 70/180 (38%), Positives = 82/180 (45%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELD 179
NT GSF C C GY R G DEC V CD C N GS+ C C G+
Sbjct: 1256 NTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWV-- 1313
Query: 180 EDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCP 353
DG C D+DEC H C C N GSY C+C G+ G C D +EC E
Sbjct: 1314 GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLC 1373
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ-APCRNYAGGYRCDCPVG 530
G+C+N G +RC C G+ + C D DECAQ C C N G +RC C G
Sbjct: 1374 DNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMFRCICNGG 1433
Score = 123 bits (297), Expect = 4e-28
Identities = 71/180 (39%), Positives = 90/180 (50%), Gaps = 7/180 (3%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C G GY GR V DEC + C C N+ GS+ C C+ GY D C D+D
Sbjct: 2351 CPHGSGYTAEGRDV---DECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMD 2407
Query: 210 ECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINEC-HEEGVCPSPGRCVNLL 380
EC + C +C NT+GS+ CSC GY E+ G C D++EC + C CVN +
Sbjct: 2408 ECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQF--LCVNTV 2465
Query: 381 GSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQA--PCRNYAGGYRCDCPVGTVRSPSG 551
G+F C CP G+ + C D DEC AQ G C A C N G +RC+C G SG
Sbjct: 2466 GAFTCRCPPGFTQHHQA--CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSG 2523
Score = 122 bits (295), Expect = 6e-28
Identities = 73/189 (38%), Positives = 88/189 (46%), Gaps = 6/189 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRG-VRGRDECAVRPPPCDQL-CHNTDGSYDCLCRTGYEL 176
R + T S+RC C GY RG DEC PC C N G+Y C C G++
Sbjct: 423 RCLPTPSSYRCECNVGYTQDVRGECIDVDECT--SSPCHHGDCVNIPGTYHCRCYPGFQA 480
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGV 347
C DVDEC C C NTEGS++C C G+E D CVD NEC +
Sbjct: 481 TPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTM 540
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCP 524
C + G C+N GSF C+C G+ L G C+D DEC G C C N G +RC C
Sbjct: 541 CVN-GVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCL 599
Query: 525 VGTVRSPSG 551
G G
Sbjct: 600 GGLAVGTDG 608
Score = 122 bits (294), Expect = 8e-28
Identities = 64/178 (35%), Positives = 83/178 (46%), Gaps = 4/178 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDED 185
+N GS+RC C G+ G RDECA CD C N G Y C C G++ ED
Sbjct: 1339 LNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTED 1398
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPSP 359
C+DVDEC + C N G + C C GYE + G C DINEC + C +
Sbjct: 1399 HRACQDVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCIN- 1457
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYA-GGYRCDCPVG 530
G C+N GS+ C CP+ + L+ G CVD + G C + G C +G
Sbjct: 1458 GVCINTPGSYLCSCPQDFELNPSGVGCVD----TRAGNCFLETHDRGDSGISCSAEIG 1511
Score = 122 bits (293), Expect = 1e-27
Identities = 73/184 (39%), Positives = 93/184 (50%), Gaps = 10/184 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPG--YRPAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYEL 176
+N IGSFRC C G Y DEC R PC Q C N GSY C C GY+L
Sbjct: 1738 INQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKL 1797
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGV 347
GA C +EC + C C +TEGSY C C G++ D C+DI+EC +
Sbjct: 1798 SPGGA-CVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQ-P 1855
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGR-CQ-APCRNYAGGYRCD 518
C + G C N++GS+ C+C G+ + G CVD DEC G+ C+ C N AG + C
Sbjct: 1856 CGN-GTCKNIIGSYNCLCFPGFVVTHNG-DCVDFDECTTLVGQVCRFGHCLNTAGSFHCL 1913
Query: 519 CPVG 530
C G
Sbjct: 1914 CQDG 1917
Score = 119 bits (286), Expect = 8e-27
Identities = 64/161 (39%), Positives = 82/161 (50%), Gaps = 5/161 (3%)
Frame = +3
Query: 84 DECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQI--CSN 254
DEC P C + +C N GS+ C C G+ + C DVDEC CQQ C N
Sbjct: 1723 DECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCIN 1782
Query: 255 TEGSYECSCEDGYE-KRGDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAE 428
GSY C C GY+ G ACV NEC E VC S G C++ GS+ C+C RG++ A+
Sbjct: 1783 IPGSYRCKCTRGYKLSPGGACVGRNECREIPNVC-SHGDCMDTEGSYMCLCHRGFQASAD 1841
Query: 429 GARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVRSPSG 551
C+D DEC + C+N G Y C C G V + +G
Sbjct: 1842 QTLCMDIDECDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNG 1882
Score = 109 bits (263), Expect = 5e-24
Identities = 65/175 (37%), Positives = 85/175 (48%), Gaps = 9/175 (5%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C G G GR + +ECA+ P C + +C N GSY C+C GYE G +C DVD
Sbjct: 670 CSSGLGITTDGRDI---NECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVD 726
Query: 210 ECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLL 380
EC ++ C C N+ GSY CSC G+ D C D++EC C S G C NL
Sbjct: 727 ECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP-CVS-GVCRNLA 784
Query: 381 GSFRCVCPRGYRLDAEGARCVD--RDEC---AQTGRCQAPCRNYAGGYRCDCPVG 530
GS+ C C G RLD G C+D + C Q RC+ + + C +G
Sbjct: 785 GSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLG 839
Score = 109 bits (262), Expect = 6e-24
Identities = 57/152 (37%), Positives = 71/152 (46%), Gaps = 4/152 (2%)
Frame = +3
Query: 108 PCDQLCH-NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSC 281
PC QLC + LC +G + DG RD++EC D C +C N GSY C C
Sbjct: 654 PC-QLCPAKNSAEFQALCSSGLGITTDG---RDINECALDPEVCANGVCENLRGSYRCVC 709
Query: 282 EDGYEK--RGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE 455
GYE G C D++EC + G C N GS+ C CP G+ + C D DE
Sbjct: 710 NLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDE 769
Query: 456 CAQTGRCQAPCRNYAGGYRCDCPVGTVRSPSG 551
C + CRN AG Y C C G+ PSG
Sbjct: 770 CLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSG 801
Score = 105 bits (251), Expect = 1e-22
Identities = 69/215 (32%), Positives = 96/215 (44%), Gaps = 35/215 (16%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRP---AGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELD 179
N IG+F CVC PG RP +G G +EC +P C + C NT GS+ C C G++
Sbjct: 2227 NLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPS 2286
Query: 180 EDGANCRDVDE--CERDT--HTCQQICSNTEG--SYECSCED--GYEKRGDACV------ 317
C D+ + C + C+ + S++E EC C G+ R + C
Sbjct: 2287 PTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSA 2346
Query: 318 ----------------DINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR 449
D++EC + G C+N LGSFRC C GY DA C+D
Sbjct: 2347 YRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDM 2406
Query: 450 DECAQTGR-CQAPCRNYAGGYRCDCPVGTVRSPSG 551
DEC+Q + C C+N G + C CP G + G
Sbjct: 2407 DECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDG 2441
Score = 99.1 bits (236), Expect = 9e-21
Identities = 72/219 (32%), Positives = 94/219 (42%), Gaps = 36/219 (16%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
R VNT GSF+CVC G+ P G+ +ECA + +C N DGS+ CLC+ G+ L
Sbjct: 504 RCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLL 563
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDI---NECH-- 335
G C D+DEC+ C+NTEGS+ C C G G CVD + C+
Sbjct: 564 APGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGA 623
Query: 336 -EEGVC--PSPGR-------CVN---------------LLGSFRCVCPRGYRLDAEGARC 440
E+G C P PG C N F+ +C G + +G
Sbjct: 624 IEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGR-- 681
Query: 441 VDRDECAQTGR--CQAPCRNYAGGYRCDCPVGTVRSPSG 551
D +ECA C N G YRC C +G SG
Sbjct: 682 -DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASG 719
Score = 97.5 bits (232), Expect = 3e-20
Identities = 71/209 (33%), Positives = 91/209 (43%), Gaps = 29/209 (13%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
N GS+RCVC GY +G+ DECA+ CD C N+ GSY C C G+ +
Sbjct: 700 NLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQ 759
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG--YEKRGDACVDINE--CH---EE 341
D C+DVDEC + +C N GSY C C G + G C+D + C +E
Sbjct: 760 DTEICKDVDEC-LSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQE 818
Query: 342 GVC-------PSPGRCVNLLGSF------RC----VCPRGYRLDAEGARCVDRDECAQ-T 467
C C LG+ RC C RG+ G C D +EC
Sbjct: 819 SRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGF-ARMTGVTCDDVNECESFP 877
Query: 468 GRC-QAPCRNYAGGYRCDCPVGTVRSPSG 551
G C C N AG +RC+CP G + SG
Sbjct: 878 GVCPNGRCVNTAGSFRCECPEGLMLDASG 906
Score = 87.8 bits (208), Expect = 2e-17
Identities = 63/172 (36%), Positives = 79/172 (45%), Gaps = 27/172 (15%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
N+ GS+ C C PG+ + DEC + P +C N GSY C C G LD
Sbjct: 742 NSPGSYSCSCPPGFHFWQDTEICKDVDEC-LSSPCVSGVCRNLAGSYTCKCGPGSRLDPS 800
Query: 186 GANCRD---------VDE--CERDTH--TCQQICSNTEGSY------EC----SCEDGYE 296
G C D + E CE + + + C T G+ C +C G+
Sbjct: 801 GTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFA 860
Query: 297 KR-GDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
+ G C D+NEC GVCP+ GRCVN GSFRC CP G LDA G CVD
Sbjct: 861 RMTGVTCDDVNECESFPGVCPN-GRCVNTAGSFRCECPEGLMLDASGRLCVD 911
Score = 87.0 bits (206), Expect = 4e-17
Identities = 39/106 (36%), Positives = 55/106 (51%), Gaps = 4/106 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDE--CAVRPPPCDQL-CHNTDGSYDCLCRTGYELDE 182
N +G +RC C G+ + + DE CA+ PP C C NT G + C+C +G++ D+
Sbjct: 2544 NQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQ 2603
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CV 317
C+DVDEC C C+NT G + C C GY + G CV
Sbjct: 2604 ALGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCV 2649
Score = 85.0 bits (201), Expect = 2e-16
Identities = 67/213 (31%), Positives = 90/213 (42%), Gaps = 37/213 (17%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPC-----DQLCHNTDGS------YD 149
R VNT GSFRC C G++P+ D +R PC +C + S +
Sbjct: 2267 RCVNTAGSFRCDCDEGFQPSPTLTECHD---IRQGPCFAEVLQTMCRSLSSSSEAVTRAE 2323
Query: 150 CLCRTG------YELDEDGANCRDVDECE---------RDTHTCQ---QICSNTE----- 260
C C G EL C RD C+ +C++ E
Sbjct: 2324 CCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSL 2383
Query: 261 GSYECSCEDGY--EKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGA 434
GS+ C C+ GY + C+D++EC + P C N GSF C CPRGY L+ +G
Sbjct: 2384 GSFRCHCQAGYTPDATATTCLDMDECSQVPK-PCTFLCKNTKGSFLCSCPRGYLLEEDGR 2442
Query: 435 RCVDRDEC-AQTGRCQAPCRNYAGGYRCDCPVG 530
C D DEC ++ CQ C N G + C CP G
Sbjct: 2443 TCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPG 2475
Score = 83.8 bits (198), Expect = 4e-16
Identities = 58/178 (32%), Positives = 76/178 (42%), Gaps = 5/178 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N+ GSF+C+C PG+ + G R D C + C + +
Sbjct: 1987 NSPGSFQCLCPPGFVLSDNGHRCFDTR-------QSFCFTRFEAGKCSVPKAFNTTKTRC 2039
Query: 192 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK---RGDACVDINECHEE-GVCPSP 359
C E C+ +++ C G+ D+ D+NEC E GVC +
Sbjct: 2040 CCSKRPG-EGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTN- 2097
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPVG 530
G CVN GSFRC CP GY LD G CVD DEC+ C Q C N GG+ C C G
Sbjct: 2098 GVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADG 2155
Score = 74.9 bits (176), Expect = 2e-13
Identities = 42/134 (31%), Positives = 57/134 (42%), Gaps = 5/134 (3%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCR--TGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECS 278
PC+ Y LC G++ + D+DEC+ CQ C NT GS++C
Sbjct: 1530 PCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCE 1589
Query: 279 CEDGYE--KRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRD 452
C GY + C DI+EC PG C N LG++ CVCP Y G C+D
Sbjct: 1590 CPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMR 1649
Query: 453 ECAQTGRCQAPCRN 494
+ C+N
Sbjct: 1650 KSVCFRHYNGTCQN 1663
Score = 72.9 bits (171), Expect = 7e-13
Identities = 54/178 (30%), Positives = 69/178 (38%), Gaps = 6/178 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNT-DGSYDCLCRTGYELDED 185
+NT GS+ C C + GV D R C H+ D C G +
Sbjct: 1461 INTPGSYLCSCPQDFELNPSGVGCVD---TRAGNCFLETHDRGDSGISCSAEIGVGVTRA 1517
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV--DINECHE-EGVCPS 356
C C + + TE C +G++ + DI+EC E G+C
Sbjct: 1518 SCCCSLGRAWGNPCELCP-MANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQG 1576
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRCDCP 524
G CVN GSF+C CP GY L C D DEC+ P C N G Y C CP
Sbjct: 1577 -GDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCP 1633
Score = 72.9 bits (171), Expect = 7e-13
Identities = 59/192 (30%), Positives = 84/192 (43%), Gaps = 12/192 (6%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECA-VRPPPC----DQLCHNTDGSYDC---LCRTG 167
NT+G++ CVC Y V G + C +R C + C N + +++ +C
Sbjct: 1623 NTLGNYTCVCPAEYLQ----VNGGNNCMDMRKSVCFRHYNGTCQN-ELAFNVTRKMCCCS 1677
Query: 168 YELDEDGANCRDVDECERDTHTCQQI-CSNTEGSYECSCEDGYEKRGDACVDINECHEEG 344
Y + + A R + C QI C N + G +DI+EC E
Sbjct: 1678 YNIGQ--AWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKP------LDIDECGEIP 1729
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQ--APCRNYAGGYRC 515
+ G C+N +GSFRC CP G+ ++ C D DEC ++ CQ A C N G YRC
Sbjct: 1730 AICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRC 1789
Query: 516 DCPVGTVRSPSG 551
C G SP G
Sbjct: 1790 KCTRGYKLSPGG 1801
Score = 70.5 bits (165), Expect = 4e-12
Identities = 56/185 (30%), Positives = 73/185 (39%), Gaps = 12/185 (6%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDE 182
N G FRC+C GY G +ECA P C + +C NT GSY C C +EL+
Sbjct: 1421 NLPGMFRCICNGGYELDRGGGNCTDINECA-DPVNCINGVCINTPGSYLCSCPQDFELNP 1479
Query: 183 DGANCRDV--DECERDTHTCQQICSNTEGSYECSCEDGYE-KRGDACVDINECHEEG--V 347
G C D C +TH + CS E G R C + +
Sbjct: 1480 SGVGCVDTRAGNCFLETH------DRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCEL 1533
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCV--DRDECAQT-GRCQA-PCRNYAGGYRC 515
CP +R +CP G + D DEC + G CQ C N G ++C
Sbjct: 1534 CPMANTT-----EYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQC 1588
Query: 516 DCPVG 530
+CP G
Sbjct: 1589 ECPPG 1593
Score = 58.4 bits (135), Expect = 2e-08
Identities = 58/201 (28%), Positives = 70/201 (34%), Gaps = 40/201 (19%)
Frame = +3
Query: 39 CGPGY-RPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDV-- 206
C G+ R G +EC P C C NT GS+ C C G LD G C DV
Sbjct: 855 CARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRL 914
Query: 207 DEC--ERDTHTCQQICSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCPS------ 356
+ C D C C C G + +AC D +CP
Sbjct: 915 EPCFLRWDEDECGVTLPGKYLMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFAS 974
Query: 357 -------------------PGRCV-----NLLGSFRCVCPRGYRLDAEGARCVDRDEC-A 461
PG C N +GSF C C G+ LDA+ C D DEC
Sbjct: 975 RDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRI 1034
Query: 462 QTGRC-QAPCRNYAGGYRCDC 521
C Q C N G + C+C
Sbjct: 1035 SPDLCGQGTCVNTPGSFECEC 1055
Score = 53.6 bits (123), Expect = 4e-07
Identities = 30/80 (37%), Positives = 38/80 (47%), Gaps = 6/80 (7%)
Frame = +3
Query: 309 ACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD--RDECAQT---G 470
AC D++EC G+C G CVN++GSF C CP G+RL A C D C G
Sbjct: 244 ACQDVDECQAVPGLCQG-GSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGG 302
Query: 471 RCQAPCRNYAGGYRCDCPVG 530
RC + +C C G
Sbjct: 303 RCAGDLAGHYTRRQCCCDRG 322
Score = 52.0 bits (119), Expect = 1e-06
Identities = 26/72 (36%), Positives = 34/72 (47%)
Frame = +3
Query: 333 HEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYR 512
H +C + GRC+ S+RC C GY D G C+D DEC + C N G Y
Sbjct: 414 HFTNLCLN-GRCLPTPSSYRCECNVGYTQDVRG-ECIDVDECTSSPCHHGDCVNIPGTYH 471
Query: 513 CDCPVGTVRSPS 548
C C G +P+
Sbjct: 472 CRCYPGFQATPT 483
Score = 45.2 bits (102), Expect = 2e-04
Identities = 31/93 (33%), Positives = 42/93 (45%), Gaps = 8/93 (8%)
Frame = +3
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQ-QICSNTEGSYECSCEDGYEKRGDACVDINEC 332
CR G+ + C+DVDEC+ CQ C N GS+ C C G+ + E
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAA--CED 289
Query: 333 HEEGVCPS---PGRCV-NLLGSF---RCVCPRG 410
+ G C S GRC +L G + +C C RG
Sbjct: 290 YRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRG 322
Score = 42.7 bits (96), Expect = 8e-04
Identities = 44/147 (29%), Positives = 54/147 (36%), Gaps = 5/147 (3%)
Frame = +3
Query: 105 PPCDQLCHNTD---GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYEC 275
P CD+ CHN G C C G+ +CERD T C G C
Sbjct: 149 PICDRGCHNGGRCIGPNRCACVYGFM----------GPQCERDYRTGP--CFGQVGPEGC 196
Query: 276 SCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE 455
++ G C C G + G L + C RG+ + C D DE
Sbjct: 197 Q----HQLTGLVCTKALCCATVG--RAWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDE 250
Query: 456 C-AQTGRCQ-APCRNYAGGYRCDCPVG 530
C A G CQ C N G + C CPVG
Sbjct: 251 CQAVPGLCQGGSCVNMVGSFHCRCPVG 277
Score = 41.9 bits (94), Expect = 0.001
Identities = 43/144 (29%), Positives = 50/144 (34%), Gaps = 6/144 (4%)
Frame = +3
Query: 3 RGVNTIGS-FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELD 179
+G N GS F C PG+R GR +C V P C + C S LC
Sbjct: 55 QGPNVCGSRFHAYCCPGWRT----FPGRSQCVV--PICRRACGEGFCSQPNLCTCA---- 104
Query: 180 EDGANCRDVDECERDTHTCQQICSN--TEGSYECSCEDGYEKRGDAC---VDINECHEEG 344
DG C C N T C C+ GY G C + CH G
Sbjct: 105 -DGTLAPSCGVSRGSG--CSVSCMNGGTCRGASCLCQKGYT--GTVCGQPICDRGCHNGG 159
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYR 416
C P RC + G C R YR
Sbjct: 160 RCIGPNRCACVYGFMGPQCERDYR 183
Score = 35.1 bits (77), Expect = 0.17
Identities = 16/41 (39%), Positives = 19/41 (46%), Gaps = 1/41 (2%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRD 203
DEC P C C N GS+ C C G+ L + A C D
Sbjct: 249 DECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
>AB177797-1|BAD16733.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 184 bits (447), Expect = 2e-46
Identities = 81/177 (45%), Positives = 102/177 (57%), Gaps = 3/177 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+N++GSFRC C GY P DEC+ P PC LC NT GS+ C C GY L+E
Sbjct: 2380 INSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEE 2439
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECH-EEGVCPSP 359
DG C+D+DEC H CQ +C NT G++ C C G+ + AC D +EC + G C +
Sbjct: 2440 DGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAH 2499
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
G C N GSFRC C +G+ L + G C D +EC RCQ C+N GGYRC CP G
Sbjct: 2500 GHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGGYRCSCPQG 2556
Score = 163 bits (397), Expect = 3e-40
Identities = 78/186 (41%), Positives = 94/186 (50%), Gaps = 5/186 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELDE 182
VNT+G+F C C PG+ + DEC+ +P PC CHNT GS+ C C G+ L
Sbjct: 2462 VNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVS 2521
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPS 356
G C DV+EC+ H CQ C N G Y CSC G+ + CVD NEC
Sbjct: 2522 SGHGCEDVNECD-GPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCG 2580
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRCDCPVGT 533
C N LG FRCVCP G+ D C D DECA + G C C N GG+ C CP G
Sbjct: 2581 SASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGY 2640
Query: 534 VRSPSG 551
R+ G
Sbjct: 2641 FRAGQG 2646
Score = 161 bits (390), Expect = 2e-39
Identities = 82/189 (43%), Positives = 105/189 (55%), Gaps = 9/189 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
NT+GSF C C G+ R DEC + P C Q C NT GS++C C GYE
Sbjct: 1004 NTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGF 1063
Query: 183 D-GANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYE--KRGDACVDINECH-EEGV 347
NC DVDEC RD C+ C+NT+GSY+C C G+E +G AC DI+EC +G+
Sbjct: 1064 MLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGL 1123
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQAPCRNYAGGYRCDCP 524
CP G+CVN++G+F+C C G++ + CVD +EC Q G C C N G YRC C
Sbjct: 1124 CPH-GQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCG 1182
Query: 525 VGTVRSPSG 551
G P G
Sbjct: 1183 QGYSLMPDG 1191
Score = 150 bits (364), Expect = 3e-36
Identities = 81/189 (42%), Positives = 98/189 (51%), Gaps = 10/189 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA---GRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYEL 176
VNT GSF C C PGY + DECA P C C NTDGSY C C G+EL
Sbjct: 1045 VNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHEL 1104
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECH-EEG 344
G C D+DEC C C N G+++CSC G++ D CVDINEC + G
Sbjct: 1105 TAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNG 1164
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-C-QAPCRNYAGGYRCD 518
C C+N GS+RC C +GY L +G C D DEC + R C Q C N GG+RC
Sbjct: 1165 GCDV--HCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCL 1222
Query: 519 CPVGTVRSP 545
C G + +P
Sbjct: 1223 CYDGFMATP 1231
Score = 141 bits (342), Expect = 1e-33
Identities = 75/187 (40%), Positives = 90/187 (48%), Gaps = 6/187 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELDE 182
+N GSF C C PG+ G DEC + C C N GSY C CR G+
Sbjct: 1298 LNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFA--G 1355
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCP 353
DG C D DEC + C C N G Y C CE G++ D AC D++EC + +C
Sbjct: 1356 DGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLC- 1414
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPVG 530
+ G C NL G FRC+C GY LD G C D +ECA C C N G Y C CP
Sbjct: 1415 AFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQD 1474
Query: 531 TVRSPSG 551
+PSG
Sbjct: 1475 FELNPSG 1481
Score = 140 bits (340), Expect = 2e-33
Identities = 80/189 (42%), Positives = 98/189 (51%), Gaps = 9/189 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VNT GSFRC C GY G+ DEC+V P C N G ++C C G+E
Sbjct: 2101 VNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGL 2160
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINECHE-EGVCP 353
C D+DEC + C C NTEGSY C+C GY R D C D++EC + + C
Sbjct: 2161 M-MTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCH 2219
Query: 354 SPG-RCVNLLGSFRCVCPRGYR-LDAEGARCVDRDEC-AQTGRC-QAPCRNYAGGYRCDC 521
+ G C NL+G+F CVCP G R L G C D +EC AQ C C N AG +RCDC
Sbjct: 2220 ARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDC 2279
Query: 522 PVGTVRSPS 548
G SP+
Sbjct: 2280 DEGFQPSPT 2288
Score = 138 bits (335), Expect = 9e-33
Identities = 75/184 (40%), Positives = 91/184 (49%), Gaps = 8/184 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN IG+F+C C G++ P +G +EC V+ CD C NT+GSY C C GY L
Sbjct: 1130 VNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMP 1189
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCP 353
DG C DVDECE + C Q C+N G + C C DG+ D CVD++EC
Sbjct: 1190 DGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHIC 1249
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG-RC--QAPCRNYAGGYRCDCP 524
G C N GSF C C GY + C D DEC G C A C N G + C C
Sbjct: 1250 LHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCL 1309
Query: 525 VGTV 536
G V
Sbjct: 1310 PGWV 1313
Score = 132 bits (320), Expect = 6e-31
Identities = 65/152 (42%), Positives = 77/152 (50%), Gaps = 7/152 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA-GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
N IG F C C G+ P DEC++ P C CHNT+GSY C C GY L EDG
Sbjct: 2143 NVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDG 2202
Query: 189 ANCRDVDEC---ERDTHTCQQICSNTEGSYECSCEDGYEK---RGDACVDINECHEEGVC 350
A CRDVDEC ++D H C N G++ C C G G+ C D NECH +
Sbjct: 2203 AMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDL 2262
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
GRCVN GSFRC C G++ C D
Sbjct: 2263 CVNGRCVNTAGSFRCDCDEGFQPSPTLTECHD 2294
Score = 132 bits (319), Expect = 8e-31
Identities = 75/190 (39%), Positives = 104/190 (54%), Gaps = 9/190 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGV--RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
++T GS+ C+C G++ + DEC R P + C N GSY+CLC G+ +
Sbjct: 1822 MDTEGSYMCLCHRGFQASADQTLCMDIDECD-RQPCGNGTCKNIIGSYNCLCFPGFVVTH 1880
Query: 183 DGANCRDVDECERDT-HTCQ-QICSNTEGSYECSCEDGYEKRGDA--CVDINECHE-EGV 347
+G +C D DEC C+ C NT GS+ C C+DG+E D CVD NEC G
Sbjct: 1881 NG-DCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGT 1939
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQ-APCRNYAGGYRCDC 521
C PG C NL GSFRC+CP G+++ ++ C+D DEC++ C C N G ++C C
Sbjct: 1940 C-LPGTCQNLEGSFRCICPPGFQVQSD--HCIDIDECSEEPNLCLFGTCTNSPGSFQCLC 1996
Query: 522 PVGTVRSPSG 551
P G V S +G
Sbjct: 1997 PPGFVLSDNG 2006
Score = 132 bits (318), Expect = 1e-30
Identities = 65/180 (36%), Positives = 85/180 (47%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
NT GS++C C PG+ +G D EC++ C C N G++ C C G++
Sbjct: 1089 NTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTP 1148
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPS 356
D C D++EC C C NTEGSY CSC GY G AC D++EC E
Sbjct: 1149 DRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCD 1208
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-C-QAPCRNYAGGYRCDCPVG 530
G C N+ G RC+C G+ + CVD DEC C C N G + C C +G
Sbjct: 1209 QGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLG 1268
Score = 131 bits (316), Expect = 2e-30
Identities = 70/179 (39%), Positives = 90/179 (50%), Gaps = 9/179 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRG-VRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELDE 182
N IGS+ C+C PG+ G DEC + C NT GS+ CLC+ G+EL
Sbjct: 1863 NIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTA 1922
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSP 359
DG NC D +EC TC C N EGS+ C C G++ + D C+DI+EC EE
Sbjct: 1923 DGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDIDECSEEPNLCLF 1982
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE--C---AQTGRCQAPCRNYAGGYRCDC 521
G C N GSF+C+CP G+ L G RC D + C + G+C P RC C
Sbjct: 1983 GTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCC 2041
Score = 130 bits (314), Expect = 3e-30
Identities = 64/161 (39%), Positives = 82/161 (50%), Gaps = 7/161 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNT 257
+EC V P C C NT GS+ C C G+ LD NC D+DEC C Q C NT
Sbjct: 988 NECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNT 1047
Query: 258 EGSYECSCEDGYEKRG---DACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAE 428
GS+EC C GYE C+D++EC + + G C N GS++C CP G+ L A+
Sbjct: 1048 PGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAK 1107
Query: 429 GARCVDRDECA-QTGRC-QAPCRNYAGGYRCDCPVGTVRSP 545
G C D DEC+ G C C N G ++C C G +P
Sbjct: 1108 GTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTP 1148
Score = 127 bits (307), Expect = 2e-29
Identities = 69/156 (44%), Positives = 83/156 (53%), Gaps = 7/156 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNT 257
+ECA P C +C NTDGS+ C C GY LD G NC D DEC H C Q C+N
Sbjct: 2086 NECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVG-HPCGQGTCTNV 2144
Query: 258 EGSYECSCEDGYEK-RGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGA 434
G +EC+C DG+E C DI+EC + RC N GS+ C CP GY L +GA
Sbjct: 2145 IGGFECACADGFEPGLMMTCEDIDECSLNPLL-CAFRCHNTEGSYLCTCPAGYTLREDGA 2203
Query: 435 RCVDRDECAQTGR-CQA---PCRNYAGGYRCDCPVG 530
C D DECA + C A C+N G + C CP G
Sbjct: 2204 MCRDVDECADGQQDCHARGMECKNLIGTFACVCPPG 2239
Score = 127 bits (306), Expect = 3e-29
Identities = 67/182 (36%), Positives = 89/182 (48%), Gaps = 11/182 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD 179
VN G++ C C PG++ P + DEC V C C NT+GS+ C+C G+EL
Sbjct: 464 VNIPGTYHCQCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELS 523
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINECHEEGVCP 353
DG NC D +EC T +C N +GS+ C C+ G+ G C+DI+EC G+C
Sbjct: 524 PDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICV 583
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVD---RDEC---AQTGRCQAPCRNYAGGYRC 515
+ G C N GSFRC C G + +G CVD R C + G C P C
Sbjct: 584 N-GHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSEC 642
Query: 516 DC 521
C
Sbjct: 643 CC 644
Score = 126 bits (304), Expect = 5e-29
Identities = 70/180 (38%), Positives = 82/180 (45%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELD 179
NT GSF C C GY R G DEC V CD C N GS+ C C G+
Sbjct: 1256 NTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWV-- 1313
Query: 180 EDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCP 353
DG C D+DEC H C C N GSY C+C G+ G C D +EC E
Sbjct: 1314 GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLC 1373
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ-APCRNYAGGYRCDCPVG 530
G+C+N G +RC C G+ + C D DECAQ C C N G +RC C G
Sbjct: 1374 DNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMFRCICNGG 1433
Score = 123 bits (297), Expect = 4e-28
Identities = 71/180 (39%), Positives = 90/180 (50%), Gaps = 7/180 (3%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C G GY GR V DEC + C C N+ GS+ C C+ GY D C D+D
Sbjct: 2351 CPHGSGYTAEGRDV---DECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMD 2407
Query: 210 ECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINEC-HEEGVCPSPGRCVNLL 380
EC + C +C NT+GS+ CSC GY E+ G C D++EC + C CVN +
Sbjct: 2408 ECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQF--LCVNTV 2465
Query: 381 GSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQA--PCRNYAGGYRCDCPVGTVRSPSG 551
G+F C CP G+ + C D DEC AQ G C A C N G +RC+C G SG
Sbjct: 2466 GAFTCRCPPGFTQHHQA--CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSG 2523
Score = 122 bits (295), Expect = 6e-28
Identities = 73/189 (38%), Positives = 88/189 (46%), Gaps = 6/189 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRG-VRGRDECAVRPPPCDQL-CHNTDGSYDCLCRTGYEL 176
R + T S+RC C GY RG DEC PC C N G+Y C C G++
Sbjct: 423 RCLPTPSSYRCECNVGYTQDVRGECIDVDECT--SSPCHHGDCVNIPGTYHCQCYPGFQA 480
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGV 347
C DVDEC C C NTEGS++C C G+E D CVD NEC +
Sbjct: 481 TPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTM 540
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCP 524
C + G C+N GSF C+C G+ L G C+D DEC G C C N G +RC C
Sbjct: 541 CVN-GVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCL 599
Query: 525 VGTVRSPSG 551
G G
Sbjct: 600 GGLAVGTDG 608
Score = 122 bits (294), Expect = 8e-28
Identities = 64/178 (35%), Positives = 83/178 (46%), Gaps = 4/178 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDED 185
+N GS+RC C G+ G RDECA CD C N G Y C C G++ ED
Sbjct: 1339 LNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTED 1398
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPSP 359
C+DVDEC + C N G + C C GYE + G C DINEC + C +
Sbjct: 1399 HRACQDVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCIN- 1457
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYA-GGYRCDCPVG 530
G C+N GS+ C CP+ + L+ G CVD + G C + G C +G
Sbjct: 1458 GVCINTPGSYLCSCPQDFELNPSGVGCVD----TRAGNCFLETHDRGDSGISCSAEIG 1511
Score = 122 bits (293), Expect = 1e-27
Identities = 73/184 (39%), Positives = 93/184 (50%), Gaps = 10/184 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPG--YRPAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYEL 176
+N IGSFRC C G Y DEC R PC Q C N GSY C C GY+L
Sbjct: 1738 INQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKL 1797
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGV 347
GA C +EC + C C +TEGSY C C G++ D C+DI+EC +
Sbjct: 1798 SPGGA-CVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQ-P 1855
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGR-CQ-APCRNYAGGYRCD 518
C + G C N++GS+ C+C G+ + G CVD DEC G+ C+ C N AG + C
Sbjct: 1856 CGN-GTCKNIIGSYNCLCFPGFVVTHNG-DCVDFDECTTLVGQVCRFGHCLNTAGSFHCL 1913
Query: 519 CPVG 530
C G
Sbjct: 1914 CQDG 1917
Score = 119 bits (286), Expect = 8e-27
Identities = 64/161 (39%), Positives = 82/161 (50%), Gaps = 5/161 (3%)
Frame = +3
Query: 84 DECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQI--CSN 254
DEC P C + +C N GS+ C C G+ + C DVDEC CQQ C N
Sbjct: 1723 DECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCIN 1782
Query: 255 TEGSYECSCEDGYE-KRGDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAE 428
GSY C C GY+ G ACV NEC E VC S G C++ GS+ C+C RG++ A+
Sbjct: 1783 IPGSYRCKCTRGYKLSPGGACVGRNECREIPNVC-SHGDCMDTEGSYMCLCHRGFQASAD 1841
Query: 429 GARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVRSPSG 551
C+D DEC + C+N G Y C C G V + +G
Sbjct: 1842 QTLCMDIDECDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNG 1882
Score = 109 bits (263), Expect = 5e-24
Identities = 65/175 (37%), Positives = 85/175 (48%), Gaps = 9/175 (5%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C G G GR + +ECA+ P C + +C N GSY C+C GYE G +C DVD
Sbjct: 670 CSSGLGITTDGRDI---NECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVD 726
Query: 210 ECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLL 380
EC ++ C C N+ GSY CSC G+ D C D++EC C S G C NL
Sbjct: 727 ECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP-CVS-GVCRNLA 784
Query: 381 GSFRCVCPRGYRLDAEGARCVD--RDEC---AQTGRCQAPCRNYAGGYRCDCPVG 530
GS+ C C G RLD G C+D + C Q RC+ + + C +G
Sbjct: 785 GSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLG 839
Score = 109 bits (262), Expect = 6e-24
Identities = 57/152 (37%), Positives = 71/152 (46%), Gaps = 4/152 (2%)
Frame = +3
Query: 108 PCDQLCH-NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSC 281
PC QLC + LC +G + DG RD++EC D C +C N GSY C C
Sbjct: 654 PC-QLCPAKNSAEFQALCSSGLGITTDG---RDINECALDPEVCANGVCENLRGSYRCVC 709
Query: 282 EDGYEK--RGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE 455
GYE G C D++EC + G C N GS+ C CP G+ + C D DE
Sbjct: 710 NLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDE 769
Query: 456 CAQTGRCQAPCRNYAGGYRCDCPVGTVRSPSG 551
C + CRN AG Y C C G+ PSG
Sbjct: 770 CLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSG 801
Score = 105 bits (251), Expect = 1e-22
Identities = 69/215 (32%), Positives = 96/215 (44%), Gaps = 35/215 (16%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRP---AGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELD 179
N IG+F CVC PG RP +G G +EC +P C + C NT GS+ C C G++
Sbjct: 2227 NLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPS 2286
Query: 180 EDGANCRDVDE--CERDT--HTCQQICSNTEG--SYECSCED--GYEKRGDACV------ 317
C D+ + C + C+ + S++E EC C G+ R + C
Sbjct: 2287 PTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSA 2346
Query: 318 ----------------DINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR 449
D++EC + G C+N LGSFRC C GY DA C+D
Sbjct: 2347 YRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDM 2406
Query: 450 DECAQTGR-CQAPCRNYAGGYRCDCPVGTVRSPSG 551
DEC+Q + C C+N G + C CP G + G
Sbjct: 2407 DECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDG 2441
Score = 99.1 bits (236), Expect = 9e-21
Identities = 72/219 (32%), Positives = 94/219 (42%), Gaps = 36/219 (16%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
R VNT GSF+CVC G+ P G+ +ECA + +C N DGS+ CLC+ G+ L
Sbjct: 504 RCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLL 563
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDI---NECH-- 335
G C D+DEC+ C+NTEGS+ C C G G CVD + C+
Sbjct: 564 APGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGA 623
Query: 336 -EEGVC--PSPGR-------CVN---------------LLGSFRCVCPRGYRLDAEGARC 440
E+G C P PG C N F+ +C G + +G
Sbjct: 624 IEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGR-- 681
Query: 441 VDRDECAQTGR--CQAPCRNYAGGYRCDCPVGTVRSPSG 551
D +ECA C N G YRC C +G SG
Sbjct: 682 -DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASG 719
Score = 97.5 bits (232), Expect = 3e-20
Identities = 71/209 (33%), Positives = 91/209 (43%), Gaps = 29/209 (13%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
N GS+RCVC GY +G+ DECA+ CD C N+ GSY C C G+ +
Sbjct: 700 NLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQ 759
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG--YEKRGDACVDINE--CH---EE 341
D C+DVDEC + +C N GSY C C G + G C+D + C +E
Sbjct: 760 DTEICKDVDEC-LSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQE 818
Query: 342 GVC-------PSPGRCVNLLGSF------RC----VCPRGYRLDAEGARCVDRDECAQ-T 467
C C LG+ RC C RG+ G C D +EC
Sbjct: 819 SRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGF-ARMTGVTCDDVNECESFP 877
Query: 468 GRC-QAPCRNYAGGYRCDCPVGTVRSPSG 551
G C C N AG +RC+CP G + SG
Sbjct: 878 GVCPNGRCVNTAGSFRCECPEGLMLDASG 906
Score = 88.2 bits (209), Expect = 2e-17
Identities = 73/207 (35%), Positives = 91/207 (43%), Gaps = 32/207 (15%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
N+ GS+ C C PG+ + DEC + P +C N GSY C C G LD
Sbjct: 742 NSPGSYSCSCPPGFHFWQDTEICKDVDEC-LSSPCVSGVCRNLAGSYTCKCGPGSRLDPS 800
Query: 186 GANCRD---------VDE--CERDTH--TCQQICSNTEGSY------EC----SCEDGYE 296
G C D + E CE + + + C T G+ C +C G+
Sbjct: 801 GTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFA 860
Query: 297 KR-GDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD-RDECAQT 467
+ G C D+NEC GVCP+ GRCVN GSFRC CP G LDA G CVD R E
Sbjct: 861 RMTGVTCDDVNECESFPGVCPN-GRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFL 919
Query: 468 GRCQAPCR-NYAGGYR---CDCPVGTV 536
+ C G YR C C +G V
Sbjct: 920 RWDEDECGVTLPGKYRMDVCCCSIGAV 946
Score = 87.0 bits (206), Expect = 4e-17
Identities = 39/106 (36%), Positives = 55/106 (51%), Gaps = 4/106 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDE--CAVRPPPCDQL-CHNTDGSYDCLCRTGYELDE 182
N +G +RC C G+ + + DE CA+ PP C C NT G + C+C +G++ D+
Sbjct: 2544 NQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQ 2603
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CV 317
C+DVDEC C C+NT G + C C GY + G CV
Sbjct: 2604 ALGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCV 2649
Score = 85.0 bits (201), Expect = 2e-16
Identities = 67/213 (31%), Positives = 90/213 (42%), Gaps = 37/213 (17%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPC-----DQLCHNTDGS------YD 149
R VNT GSFRC C G++P+ D +R PC +C + S +
Sbjct: 2267 RCVNTAGSFRCDCDEGFQPSPTLTECHD---IRQGPCFAEVLQTMCRSLSSSSEAVTRAE 2323
Query: 150 CLCRTG------YELDEDGANCRDVDECE---------RDTHTCQ---QICSNTE----- 260
C C G EL C RD C+ +C++ E
Sbjct: 2324 CCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSL 2383
Query: 261 GSYECSCEDGY--EKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGA 434
GS+ C C+ GY + C+D++EC + P C N GSF C CPRGY L+ +G
Sbjct: 2384 GSFRCHCQAGYTPDATATTCLDMDECSQVPK-PCTFLCKNTKGSFLCSCPRGYLLEEDGR 2442
Query: 435 RCVDRDEC-AQTGRCQAPCRNYAGGYRCDCPVG 530
C D DEC ++ CQ C N G + C CP G
Sbjct: 2443 TCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPG 2475
Score = 83.8 bits (198), Expect = 4e-16
Identities = 58/178 (32%), Positives = 76/178 (42%), Gaps = 5/178 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N+ GSF+C+C PG+ + G R D C + C + +
Sbjct: 1987 NSPGSFQCLCPPGFVLSDNGHRCFDTR-------QSFCFTRFEAGKCSVPKAFNTTKTRC 2039
Query: 192 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK---RGDACVDINECHEE-GVCPSP 359
C E C+ +++ C G+ D+ D+NEC E GVC +
Sbjct: 2040 CCSKRPG-EGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTN- 2097
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPVG 530
G CVN GSFRC CP GY LD G CVD DEC+ C Q C N GG+ C C G
Sbjct: 2098 GVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADG 2155
Score = 74.9 bits (176), Expect = 2e-13
Identities = 42/134 (31%), Positives = 57/134 (42%), Gaps = 5/134 (3%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCR--TGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECS 278
PC+ Y LC G++ + D+DEC+ CQ C NT GS++C
Sbjct: 1530 PCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCE 1589
Query: 279 CEDGYE--KRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRD 452
C GY + C DI+EC PG C N LG++ CVCP Y G C+D
Sbjct: 1590 CPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMR 1649
Query: 453 ECAQTGRCQAPCRN 494
+ C+N
Sbjct: 1650 KSVCFRHYNGTCQN 1663
Score = 72.9 bits (171), Expect = 7e-13
Identities = 54/178 (30%), Positives = 69/178 (38%), Gaps = 6/178 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNT-DGSYDCLCRTGYELDED 185
+NT GS+ C C + GV D R C H+ D C G +
Sbjct: 1461 INTPGSYLCSCPQDFELNPSGVGCVD---TRAGNCFLETHDRGDSGISCSAEIGVGVTRA 1517
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV--DINECHE-EGVCPS 356
C C + + TE C +G++ + DI+EC E G+C
Sbjct: 1518 SCCCSLGRAWGNPCELCP-MANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQG 1576
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRCDCP 524
G CVN GSF+C CP GY L C D DEC+ P C N G Y C CP
Sbjct: 1577 -GDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCP 1633
Score = 72.9 bits (171), Expect = 7e-13
Identities = 59/192 (30%), Positives = 84/192 (43%), Gaps = 12/192 (6%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECA-VRPPPC----DQLCHNTDGSYDC---LCRTG 167
NT+G++ CVC Y V G + C +R C + C N + +++ +C
Sbjct: 1623 NTLGNYTCVCPAEYLQ----VNGGNNCMDMRKSVCFRHYNGTCQN-ELAFNVTRKMCCCS 1677
Query: 168 YELDEDGANCRDVDECERDTHTCQQI-CSNTEGSYECSCEDGYEKRGDACVDINECHEEG 344
Y + + A R + C QI C N + G +DI+EC E
Sbjct: 1678 YNIGQ--AWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKP------LDIDECGEIP 1729
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQ--APCRNYAGGYRC 515
+ G C+N +GSFRC CP G+ ++ C D DEC ++ CQ A C N G YRC
Sbjct: 1730 AICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRC 1789
Query: 516 DCPVGTVRSPSG 551
C G SP G
Sbjct: 1790 KCTRGYKLSPGG 1801
Score = 70.5 bits (165), Expect = 4e-12
Identities = 56/185 (30%), Positives = 73/185 (39%), Gaps = 12/185 (6%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDE 182
N G FRC+C GY G +ECA P C + +C NT GSY C C +EL+
Sbjct: 1421 NLPGMFRCICNGGYELDRGGGNCTDINECA-DPVNCINGVCINTPGSYLCSCPQDFELNP 1479
Query: 183 DGANCRDV--DECERDTHTCQQICSNTEGSYECSCEDGYE-KRGDACVDINECHEEG--V 347
G C D C +TH + CS E G R C + +
Sbjct: 1480 SGVGCVDTRAGNCFLETH------DRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCEL 1533
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCV--DRDECAQT-GRCQA-PCRNYAGGYRC 515
CP +R +CP G + D DEC + G CQ C N G ++C
Sbjct: 1534 CPMANTT-----EYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQC 1588
Query: 516 DCPVG 530
+CP G
Sbjct: 1589 ECPPG 1593
Score = 59.3 bits (137), Expect = 9e-09
Identities = 58/201 (28%), Positives = 70/201 (34%), Gaps = 40/201 (19%)
Frame = +3
Query: 39 CGPGY-RPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDV-- 206
C G+ R G +EC P C C NT GS+ C C G LD G C DV
Sbjct: 855 CARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRL 914
Query: 207 DEC--ERDTHTCQQICSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCPS------ 356
+ C D C C C G + +AC D +CP
Sbjct: 915 EPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFAS 974
Query: 357 -------------------PGRCV-----NLLGSFRCVCPRGYRLDAEGARCVDRDEC-A 461
PG C N +GSF C C G+ LDA+ C D DEC
Sbjct: 975 RDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRI 1034
Query: 462 QTGRC-QAPCRNYAGGYRCDC 521
C Q C N G + C+C
Sbjct: 1035 SPDLCGQGTCVNTPGSFECEC 1055
Score = 53.6 bits (123), Expect = 4e-07
Identities = 30/80 (37%), Positives = 38/80 (47%), Gaps = 6/80 (7%)
Frame = +3
Query: 309 ACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD--RDECAQT---G 470
AC D++EC G+C G CVN++GSF C CP G+RL A C D C G
Sbjct: 244 ACQDVDECQAVPGLCQG-GSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGG 302
Query: 471 RCQAPCRNYAGGYRCDCPVG 530
RC + +C C G
Sbjct: 303 RCAGDLAGHYTRRQCCCDRG 322
Score = 52.8 bits (121), Expect = 8e-07
Identities = 26/72 (36%), Positives = 34/72 (47%)
Frame = +3
Query: 333 HEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYR 512
H +C + GRC+ S+RC C GY D G C+D DEC + C N G Y
Sbjct: 414 HFTNLCLN-GRCLPTPSSYRCECNVGYTQDVRG-ECIDVDECTSSPCHHGDCVNIPGTYH 471
Query: 513 CDCPVGTVRSPS 548
C C G +P+
Sbjct: 472 CQCYPGFQATPT 483
Score = 45.2 bits (102), Expect = 2e-04
Identities = 31/93 (33%), Positives = 42/93 (45%), Gaps = 8/93 (8%)
Frame = +3
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQ-QICSNTEGSYECSCEDGYEKRGDACVDINEC 332
CR G+ + C+DVDEC+ CQ C N GS+ C C G+ + E
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAA--CED 289
Query: 333 HEEGVCPS---PGRCV-NLLGSF---RCVCPRG 410
+ G C S GRC +L G + +C C RG
Sbjct: 290 YRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRG 322
Score = 42.7 bits (96), Expect = 8e-04
Identities = 44/147 (29%), Positives = 54/147 (36%), Gaps = 5/147 (3%)
Frame = +3
Query: 105 PPCDQLCHNTD---GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYEC 275
P CD+ CHN G C C G+ +CERD T C G C
Sbjct: 149 PICDRGCHNGGRCIGPNRCACVYGFM----------GPQCERDYRTGP--CFGQVGPEGC 196
Query: 276 SCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE 455
++ G C C G + G L + C RG+ + C D DE
Sbjct: 197 Q----HQLTGLVCTKALCCATVG--RAWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDE 250
Query: 456 C-AQTGRCQ-APCRNYAGGYRCDCPVG 530
C A G CQ C N G + C CPVG
Sbjct: 251 CQAVPGLCQGGSCVNMVGSFHCRCPVG 277
Score = 41.9 bits (94), Expect = 0.001
Identities = 43/144 (29%), Positives = 50/144 (34%), Gaps = 6/144 (4%)
Frame = +3
Query: 3 RGVNTIGS-FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELD 179
+G N GS F C PG+R GR +C V P C + C S LC
Sbjct: 55 QGPNVCGSRFHAYCCPGWRT----FPGRSQCVV--PICRRACGEGFCSQPNLCTCA---- 104
Query: 180 EDGANCRDVDECERDTHTCQQICSN--TEGSYECSCEDGYEKRGDAC---VDINECHEEG 344
DG C C N T C C+ GY G C + CH G
Sbjct: 105 -DGTLAPSCGVSRGSG--CSVSCMNGGTCRGASCLCQKGYT--GTVCGQPICDRGCHNGG 159
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYR 416
C P RC + G C R YR
Sbjct: 160 RCIGPNRCACVYGFMGPQCERDYR 183
Score = 35.1 bits (77), Expect = 0.17
Identities = 16/41 (39%), Positives = 19/41 (46%), Gaps = 1/41 (2%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRD 203
DEC P C C N GS+ C C G+ L + A C D
Sbjct: 249 DECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
>AB053450-1|BAB47408.2| 2816|Homo sapiens fibrillin3 protein.
Length = 2816
Score = 184 bits (447), Expect = 2e-46
Identities = 81/177 (45%), Positives = 102/177 (57%), Gaps = 3/177 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+N++GSFRC C GY P DEC+ P PC LC NT GS+ C C GY L+E
Sbjct: 2387 INSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEE 2446
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECH-EEGVCPSP 359
DG C+D+DEC H CQ +C NT G++ C C G+ + AC D +EC + G C +
Sbjct: 2447 DGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAH 2506
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
G C N GSFRC C +G+ L + G C D +EC RCQ C+N GGYRC CP G
Sbjct: 2507 GHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGGYRCSCPQG 2563
Score = 163 bits (397), Expect = 3e-40
Identities = 78/186 (41%), Positives = 94/186 (50%), Gaps = 5/186 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELDE 182
VNT+G+F C C PG+ + DEC+ +P PC CHNT GS+ C C G+ L
Sbjct: 2469 VNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVS 2528
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPS 356
G C DV+EC+ H CQ C N G Y CSC G+ + CVD NEC
Sbjct: 2529 SGHGCEDVNECD-GPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCG 2587
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRCDCPVGT 533
C N LG FRCVCP G+ D C D DECA + G C C N GG+ C CP G
Sbjct: 2588 SASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGY 2647
Query: 534 VRSPSG 551
R+ G
Sbjct: 2648 FRAGQG 2653
Score = 161 bits (390), Expect = 2e-39
Identities = 82/189 (43%), Positives = 105/189 (55%), Gaps = 9/189 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
NT+GSF C C G+ R DEC + P C Q C NT GS++C C GYE
Sbjct: 1011 NTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGF 1070
Query: 183 D-GANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYE--KRGDACVDINECH-EEGV 347
NC DVDEC RD C+ C+NT+GSY+C C G+E +G AC DI+EC +G+
Sbjct: 1071 MLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGL 1130
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQAPCRNYAGGYRCDCP 524
CP G+CVN++G+F+C C G++ + CVD +EC Q G C C N G YRC C
Sbjct: 1131 CPH-GQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCG 1189
Query: 525 VGTVRSPSG 551
G P G
Sbjct: 1190 QGYSLMPDG 1198
Score = 150 bits (364), Expect = 3e-36
Identities = 81/189 (42%), Positives = 98/189 (51%), Gaps = 10/189 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA---GRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYEL 176
VNT GSF C C PGY + DECA P C C NTDGSY C C G+EL
Sbjct: 1052 VNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHEL 1111
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECH-EEG 344
G C D+DEC C C N G+++CSC G++ D CVDINEC + G
Sbjct: 1112 TAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNG 1171
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-C-QAPCRNYAGGYRCD 518
C C+N GS+RC C +GY L +G C D DEC + R C Q C N GG+RC
Sbjct: 1172 GCDV--HCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCL 1229
Query: 519 CPVGTVRSP 545
C G + +P
Sbjct: 1230 CYDGFMATP 1238
Score = 141 bits (341), Expect = 2e-33
Identities = 75/187 (40%), Positives = 90/187 (48%), Gaps = 6/187 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELDE 182
+N GSF C C PG+ G DEC + C C N GSY C CR G+
Sbjct: 1305 LNIPGSFSCRCLPGWVGDGFECHDLDECISQEHRCSPRGDCLNVPGSYRCTCRQGFA--G 1362
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCP 353
DG C D DEC + C C N G Y C CE G++ D AC D++EC + +C
Sbjct: 1363 DGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLC- 1421
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPVG 530
+ G C NL G FRC+C GY LD G C D +ECA C C N G Y C CP
Sbjct: 1422 AFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQD 1481
Query: 531 TVRSPSG 551
+PSG
Sbjct: 1482 FELNPSG 1488
Score = 140 bits (340), Expect = 2e-33
Identities = 80/189 (42%), Positives = 98/189 (51%), Gaps = 9/189 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VNT GSFRC C GY G+ DEC+V P C N G ++C C G+E
Sbjct: 2108 VNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGL 2167
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINECHE-EGVCP 353
C D+DEC + C C NTEGSY C+C GY R D C D++EC + + C
Sbjct: 2168 M-MTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCH 2226
Query: 354 SPG-RCVNLLGSFRCVCPRGYR-LDAEGARCVDRDEC-AQTGRC-QAPCRNYAGGYRCDC 521
+ G C NL+G+F CVCP G R L G C D +EC AQ C C N AG +RCDC
Sbjct: 2227 ARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDC 2286
Query: 522 PVGTVRSPS 548
G SP+
Sbjct: 2287 DEGFQPSPT 2295
Score = 138 bits (335), Expect = 9e-33
Identities = 75/184 (40%), Positives = 91/184 (49%), Gaps = 8/184 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN IG+F+C C G++ P +G +EC V+ CD C NT+GSY C C GY L
Sbjct: 1137 VNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMP 1196
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCP 353
DG C DVDECE + C Q C+N G + C C DG+ D CVD++EC
Sbjct: 1197 DGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHIC 1256
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG-RC--QAPCRNYAGGYRCDCP 524
G C N GSF C C GY + C D DEC G C A C N G + C C
Sbjct: 1257 LHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCL 1316
Query: 525 VGTV 536
G V
Sbjct: 1317 PGWV 1320
Score = 132 bits (320), Expect = 6e-31
Identities = 65/152 (42%), Positives = 77/152 (50%), Gaps = 7/152 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA-GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
N IG F C C G+ P DEC++ P C CHNT+GSY C C GY L EDG
Sbjct: 2150 NVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDG 2209
Query: 189 ANCRDVDEC---ERDTHTCQQICSNTEGSYECSCEDGYEK---RGDACVDINECHEEGVC 350
A CRDVDEC ++D H C N G++ C C G G+ C D NECH +
Sbjct: 2210 AMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDL 2269
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
GRCVN GSFRC C G++ C D
Sbjct: 2270 CVNGRCVNTAGSFRCDCDEGFQPSPTLTECHD 2301
Score = 132 bits (319), Expect = 8e-31
Identities = 75/190 (39%), Positives = 104/190 (54%), Gaps = 9/190 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGV--RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
++T GS+ C+C G++ + DEC R P + C N GSY+CLC G+ +
Sbjct: 1829 MDTEGSYMCLCHRGFQASADQTLCMDIDECD-RQPCGNGTCKNIIGSYNCLCFPGFVVTH 1887
Query: 183 DGANCRDVDECERDT-HTCQ-QICSNTEGSYECSCEDGYEKRGDA--CVDINECHE-EGV 347
+G +C D DEC C+ C NT GS+ C C+DG+E D CVD NEC G
Sbjct: 1888 NG-DCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGT 1946
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQ-APCRNYAGGYRCDC 521
C PG C NL GSFRC+CP G+++ ++ C+D DEC++ C C N G ++C C
Sbjct: 1947 C-LPGTCQNLEGSFRCICPPGFQVQSD--HCIDIDECSEEPNLCLFGTCTNSPGSFQCLC 2003
Query: 522 PVGTVRSPSG 551
P G V S +G
Sbjct: 2004 PPGFVLSDNG 2013
Score = 132 bits (318), Expect = 1e-30
Identities = 65/180 (36%), Positives = 85/180 (47%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
NT GS++C C PG+ +G D EC++ C C N G++ C C G++
Sbjct: 1096 NTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTP 1155
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPS 356
D C D++EC C C NTEGSY CSC GY G AC D++EC E
Sbjct: 1156 DRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCD 1215
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-C-QAPCRNYAGGYRCDCPVG 530
G C N+ G RC+C G+ + CVD DEC C C N G + C C +G
Sbjct: 1216 QGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLG 1275
Score = 131 bits (316), Expect = 2e-30
Identities = 70/179 (39%), Positives = 90/179 (50%), Gaps = 9/179 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRG-VRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELDE 182
N IGS+ C+C PG+ G DEC + C NT GS+ CLC+ G+EL
Sbjct: 1870 NIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTA 1929
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSP 359
DG NC D +EC TC C N EGS+ C C G++ + D C+DI+EC EE
Sbjct: 1930 DGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDIDECSEEPNLCLF 1989
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE--C---AQTGRCQAPCRNYAGGYRCDC 521
G C N GSF+C+CP G+ L G RC D + C + G+C P RC C
Sbjct: 1990 GTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCC 2048
Score = 130 bits (314), Expect = 3e-30
Identities = 64/161 (39%), Positives = 82/161 (50%), Gaps = 7/161 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNT 257
+EC V P C C NT GS+ C C G+ LD NC D+DEC C Q C NT
Sbjct: 995 NECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNT 1054
Query: 258 EGSYECSCEDGYEKRG---DACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAE 428
GS+EC C GYE C+D++EC + + G C N GS++C CP G+ L A+
Sbjct: 1055 PGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAK 1114
Query: 429 GARCVDRDECA-QTGRC-QAPCRNYAGGYRCDCPVGTVRSP 545
G C D DEC+ G C C N G ++C C G +P
Sbjct: 1115 GTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTP 1155
Score = 127 bits (307), Expect = 2e-29
Identities = 69/156 (44%), Positives = 83/156 (53%), Gaps = 7/156 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNT 257
+ECA P C +C NTDGS+ C C GY LD G NC D DEC H C Q C+N
Sbjct: 2093 NECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVG-HPCGQGTCTNV 2151
Query: 258 EGSYECSCEDGYEK-RGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGA 434
G +EC+C DG+E C DI+EC + RC N GS+ C CP GY L +GA
Sbjct: 2152 IGGFECACADGFEPGLMMTCEDIDECSLNPLL-CAFRCHNTEGSYLCTCPAGYTLREDGA 2210
Query: 435 RCVDRDECAQTGR-CQA---PCRNYAGGYRCDCPVG 530
C D DECA + C A C+N G + C CP G
Sbjct: 2211 MCRDVDECADGQQDCHARGMECKNLIGTFACVCPPG 2246
Score = 126 bits (305), Expect = 4e-29
Identities = 67/182 (36%), Positives = 89/182 (48%), Gaps = 11/182 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD 179
VN G++ C C PG++ P + DEC V C C NT+GS+ C+C G+EL
Sbjct: 471 VNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELS 530
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINECHEEGVCP 353
DG NC D +EC T +C N +GS+ C C+ G+ G C+DI+EC G+C
Sbjct: 531 PDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICV 590
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVD---RDEC---AQTGRCQAPCRNYAGGYRC 515
+ G C N GSFRC C G + +G CVD R C + G C P C
Sbjct: 591 N-GHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSEC 649
Query: 516 DC 521
C
Sbjct: 650 CC 651
Score = 126 bits (303), Expect = 7e-29
Identities = 70/180 (38%), Positives = 82/180 (45%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELD 179
NT GSF C C GY R G DEC V CD C N GS+ C C G+
Sbjct: 1263 NTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWV-- 1320
Query: 180 EDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCP 353
DG C D+DEC H C C N GSY C+C G+ G C D +EC E
Sbjct: 1321 GDGFECHDLDECISQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLC 1380
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ-APCRNYAGGYRCDCPVG 530
G+C+N G +RC C G+ + C D DECAQ C C N G +RC C G
Sbjct: 1381 DNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMFRCICNGG 1440
Score = 123 bits (297), Expect = 4e-28
Identities = 71/180 (39%), Positives = 90/180 (50%), Gaps = 7/180 (3%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C G GY GR V DEC + C C N+ GS+ C C+ GY D C D+D
Sbjct: 2358 CPHGSGYTAEGRDV---DECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMD 2414
Query: 210 ECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINEC-HEEGVCPSPGRCVNLL 380
EC + C +C NT+GS+ CSC GY E+ G C D++EC + C CVN +
Sbjct: 2415 ECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQF--LCVNTV 2472
Query: 381 GSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQA--PCRNYAGGYRCDCPVGTVRSPSG 551
G+F C CP G+ + C D DEC AQ G C A C N G +RC+C G SG
Sbjct: 2473 GAFTCRCPPGFTQHHQA--CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSG 2530
Score = 122 bits (295), Expect = 6e-28
Identities = 73/189 (38%), Positives = 88/189 (46%), Gaps = 6/189 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRG-VRGRDECAVRPPPCDQL-CHNTDGSYDCLCRTGYEL 176
R + T S+RC C GY RG DEC PC C N G+Y C C G++
Sbjct: 430 RCLPTPSSYRCECNVGYTQDVRGECIDVDECT--SSPCHHGDCVNIPGTYHCRCYPGFQA 487
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGV 347
C DVDEC C C NTEGS++C C G+E D CVD NEC +
Sbjct: 488 TPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTM 547
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCP 524
C + G C+N GSF C+C G+ L G C+D DEC G C C N G +RC C
Sbjct: 548 CVN-GVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCL 606
Query: 525 VGTVRSPSG 551
G G
Sbjct: 607 GGLAVGTDG 615
Score = 122 bits (294), Expect = 8e-28
Identities = 64/178 (35%), Positives = 83/178 (46%), Gaps = 4/178 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDED 185
+N GS+RC C G+ G RDECA CD C N G Y C C G++ ED
Sbjct: 1346 LNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTED 1405
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPSP 359
C+DVDEC + C N G + C C GYE + G C DINEC + C +
Sbjct: 1406 HRACQDVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCIN- 1464
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYA-GGYRCDCPVG 530
G C+N GS+ C CP+ + L+ G CVD + G C + G C +G
Sbjct: 1465 GVCINTPGSYLCSCPQDFELNPSGVGCVD----TRAGNCFLETHDRGDSGISCSAEIG 1518
Score = 122 bits (294), Expect = 8e-28
Identities = 73/184 (39%), Positives = 93/184 (50%), Gaps = 10/184 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPG--YRPAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYEL 176
+N IGSFRC C G Y DEC R PC Q C N GSY C C GY+L
Sbjct: 1745 INQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKL 1804
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGV 347
GA C +EC + C C +TEGSY C C G++ D C+DI+EC +
Sbjct: 1805 SPGGA-CVGQNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQ-P 1862
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGR-CQ-APCRNYAGGYRCD 518
C + G C N++GS+ C+C G+ + G CVD DEC G+ C+ C N AG + C
Sbjct: 1863 CGN-GTCKNIIGSYNCLCFPGFVVTHNG-DCVDFDECTTLVGQVCRFGHCLNTAGSFHCL 1920
Query: 519 CPVG 530
C G
Sbjct: 1921 CQDG 1924
Score = 119 bits (286), Expect = 8e-27
Identities = 64/161 (39%), Positives = 82/161 (50%), Gaps = 5/161 (3%)
Frame = +3
Query: 84 DECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQI--CSN 254
DEC P C + +C N GS+ C C G+ + C DVDEC CQQ C N
Sbjct: 1730 DECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCIN 1789
Query: 255 TEGSYECSCEDGYE-KRGDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAE 428
GSY C C GY+ G ACV NEC E VC S G C++ GS+ C+C RG++ A+
Sbjct: 1790 IPGSYRCKCTRGYKLSPGGACVGQNECREIPNVC-SHGDCMDTEGSYMCLCHRGFQASAD 1848
Query: 429 GARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVRSPSG 551
C+D DEC + C+N G Y C C G V + +G
Sbjct: 1849 QTLCMDIDECDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNG 1889
Score = 109 bits (263), Expect = 5e-24
Identities = 65/175 (37%), Positives = 85/175 (48%), Gaps = 9/175 (5%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C G G GR + +ECA+ P C + +C N GSY C+C GYE G +C DVD
Sbjct: 677 CSSGLGITTDGRDI---NECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVD 733
Query: 210 ECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLL 380
EC ++ C C N+ GSY CSC G+ D C D++EC C S G C NL
Sbjct: 734 ECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP-CVS-GVCRNLA 791
Query: 381 GSFRCVCPRGYRLDAEGARCVD--RDEC---AQTGRCQAPCRNYAGGYRCDCPVG 530
GS+ C C G RLD G C+D + C Q RC+ + + C +G
Sbjct: 792 GSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLG 846
Score = 109 bits (262), Expect = 6e-24
Identities = 57/152 (37%), Positives = 71/152 (46%), Gaps = 4/152 (2%)
Frame = +3
Query: 108 PCDQLCH-NTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSC 281
PC QLC + LC +G + DG RD++EC D C +C N GSY C C
Sbjct: 661 PC-QLCPAKNSAEFQALCSSGLGITTDG---RDINECALDPEVCANGVCENLRGSYRCVC 716
Query: 282 EDGYEK--RGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE 455
GYE G C D++EC + G C N GS+ C CP G+ + C D DE
Sbjct: 717 NLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDE 776
Query: 456 CAQTGRCQAPCRNYAGGYRCDCPVGTVRSPSG 551
C + CRN AG Y C C G+ PSG
Sbjct: 777 CLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSG 808
Score = 105 bits (251), Expect = 1e-22
Identities = 69/215 (32%), Positives = 96/215 (44%), Gaps = 35/215 (16%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRP---AGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELD 179
N IG+F CVC PG RP +G G +EC +P C + C NT GS+ C C G++
Sbjct: 2234 NLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPS 2293
Query: 180 EDGANCRDVDE--CERDT--HTCQQICSNTEG--SYECSCED--GYEKRGDACV------ 317
C D+ + C + C+ + S++E EC C G+ R + C
Sbjct: 2294 PTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSA 2353
Query: 318 ----------------DINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR 449
D++EC + G C+N LGSFRC C GY DA C+D
Sbjct: 2354 YRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDM 2413
Query: 450 DECAQTGR-CQAPCRNYAGGYRCDCPVGTVRSPSG 551
DEC+Q + C C+N G + C CP G + G
Sbjct: 2414 DECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDG 2448
Score = 99.1 bits (236), Expect = 9e-21
Identities = 72/219 (32%), Positives = 94/219 (42%), Gaps = 36/219 (16%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
R VNT GSF+CVC G+ P G+ +ECA + +C N DGS+ CLC+ G+ L
Sbjct: 511 RCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLL 570
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDI---NECH-- 335
G C D+DEC+ C+NTEGS+ C C G G CVD + C+
Sbjct: 571 APGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGA 630
Query: 336 -EEGVC--PSPGR-------CVN---------------LLGSFRCVCPRGYRLDAEGARC 440
E+G C P PG C N F+ +C G + +G
Sbjct: 631 IEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGR-- 688
Query: 441 VDRDECAQTGR--CQAPCRNYAGGYRCDCPVGTVRSPSG 551
D +ECA C N G YRC C +G SG
Sbjct: 689 -DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASG 726
Score = 97.5 bits (232), Expect = 3e-20
Identities = 71/209 (33%), Positives = 91/209 (43%), Gaps = 29/209 (13%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
N GS+RCVC GY +G+ DECA+ CD C N+ GSY C C G+ +
Sbjct: 707 NLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQ 766
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG--YEKRGDACVDINE--CH---EE 341
D C+DVDEC + +C N GSY C C G + G C+D + C +E
Sbjct: 767 DTEICKDVDEC-LSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQE 825
Query: 342 GVC-------PSPGRCVNLLGSF------RC----VCPRGYRLDAEGARCVDRDECAQ-T 467
C C LG+ RC C RG+ G C D +EC
Sbjct: 826 SRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGF-ARMTGVTCDDVNECESFP 884
Query: 468 GRC-QAPCRNYAGGYRCDCPVGTVRSPSG 551
G C C N AG +RC+CP G + SG
Sbjct: 885 GVCPNGRCVNTAGSFRCECPEGLMLDASG 913
Score = 88.2 bits (209), Expect = 2e-17
Identities = 73/207 (35%), Positives = 91/207 (43%), Gaps = 32/207 (15%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
N+ GS+ C C PG+ + DEC + P +C N GSY C C G LD
Sbjct: 749 NSPGSYSCSCPPGFHFWQDTEICKDVDEC-LSSPCVSGVCRNLAGSYTCKCGPGSRLDPS 807
Query: 186 GANCRD---------VDE--CERDTH--TCQQICSNTEGSY------EC----SCEDGYE 296
G C D + E CE + + + C T G+ C +C G+
Sbjct: 808 GTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFA 867
Query: 297 KR-GDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD-RDECAQT 467
+ G C D+NEC GVCP+ GRCVN GSFRC CP G LDA G CVD R E
Sbjct: 868 RMTGVTCDDVNECESFPGVCPN-GRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFL 926
Query: 468 GRCQAPCR-NYAGGYR---CDCPVGTV 536
+ C G YR C C +G V
Sbjct: 927 RWDEDECGVTLPGKYRMDVCCCSIGAV 953
Score = 87.0 bits (206), Expect = 4e-17
Identities = 39/106 (36%), Positives = 55/106 (51%), Gaps = 4/106 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDE--CAVRPPPCDQL-CHNTDGSYDCLCRTGYELDE 182
N +G +RC C G+ + + DE CA+ PP C C NT G + C+C +G++ D+
Sbjct: 2551 NQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQ 2610
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CV 317
C+DVDEC C C+NT G + C C GY + G CV
Sbjct: 2611 ALGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCV 2656
Score = 85.0 bits (201), Expect = 2e-16
Identities = 67/213 (31%), Positives = 90/213 (42%), Gaps = 37/213 (17%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPC-----DQLCHNTDGS------YD 149
R VNT GSFRC C G++P+ D +R PC +C + S +
Sbjct: 2274 RCVNTAGSFRCDCDEGFQPSPTLTECHD---IRQGPCFAEVLQTMCRSLSSSSEAVTRAE 2330
Query: 150 CLCRTG------YELDEDGANCRDVDECE---------RDTHTCQ---QICSNTE----- 260
C C G EL C RD C+ +C++ E
Sbjct: 2331 CCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSL 2390
Query: 261 GSYECSCEDGY--EKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGA 434
GS+ C C+ GY + C+D++EC + P C N GSF C CPRGY L+ +G
Sbjct: 2391 GSFRCHCQAGYTPDATATTCLDMDECSQVPK-PCTFLCKNTKGSFLCSCPRGYLLEEDGR 2449
Query: 435 RCVDRDEC-AQTGRCQAPCRNYAGGYRCDCPVG 530
C D DEC ++ CQ C N G + C CP G
Sbjct: 2450 TCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPG 2482
Score = 83.8 bits (198), Expect = 4e-16
Identities = 58/178 (32%), Positives = 76/178 (42%), Gaps = 5/178 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N+ GSF+C+C PG+ + G R D C + C + +
Sbjct: 1994 NSPGSFQCLCPPGFVLSDNGHRCFDTR-------QSFCFTRFEAGKCSVPKAFNTTKTRC 2046
Query: 192 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK---RGDACVDINECHEE-GVCPSP 359
C E C+ +++ C G+ D+ D+NEC E GVC +
Sbjct: 2047 CCSKRPG-EGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTN- 2104
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPVG 530
G CVN GSFRC CP GY LD G CVD DEC+ C Q C N GG+ C C G
Sbjct: 2105 GVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADG 2162
Score = 76.2 bits (179), Expect = 7e-14
Identities = 44/135 (32%), Positives = 60/135 (44%), Gaps = 6/135 (4%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCR--TGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECS 278
PC+ Y LC G++ + D+DEC+ CQ C NT GS++C
Sbjct: 1537 PCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCE 1596
Query: 279 CEDGYE--KRGDACVDINECH-EEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR 449
C GY + C DI+EC G+C PG C N LG++ CVCP Y G C+D
Sbjct: 1597 CPPGYHLSEHTRICEDIDECSTHSGIC-GPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDM 1655
Query: 450 DECAQTGRCQAPCRN 494
+ C+N
Sbjct: 1656 RKSVCFRHYNGTCQN 1670
Score = 74.1 bits (174), Expect = 3e-13
Identities = 55/178 (30%), Positives = 71/178 (39%), Gaps = 6/178 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNT-DGSYDCLCRTGYELDED 185
+NT GS+ C C + GV D R C H+ D C G +
Sbjct: 1468 INTPGSYLCSCPQDFELNPSGVGCVD---TRAGNCFLETHDRGDSGISCSAEIGVGVTRA 1524
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV--DINECHE-EGVCPS 356
C C + + TE C +G++ + DI+EC E G+C
Sbjct: 1525 SCCCSLGRAWGNPCELCP-MANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQG 1583
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRC-QAPCRNYAGGYRCDCP 524
G CVN GSF+C CP GY L C D DEC+ +G C C N G Y C CP
Sbjct: 1584 -GDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSGICGPGTCYNTLGNYTCVCP 1640
Score = 72.9 bits (171), Expect = 7e-13
Identities = 59/192 (30%), Positives = 84/192 (43%), Gaps = 12/192 (6%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECA-VRPPPC----DQLCHNTDGSYDC---LCRTG 167
NT+G++ CVC Y V G + C +R C + C N + +++ +C
Sbjct: 1630 NTLGNYTCVCPAEYLQ----VNGGNNCMDMRKSVCFRHYNGTCQN-ELAFNVTRKMCCCS 1684
Query: 168 YELDEDGANCRDVDECERDTHTCQQI-CSNTEGSYECSCEDGYEKRGDACVDINECHEEG 344
Y + + A R + C QI C N + G +DI+EC E
Sbjct: 1685 YNIGQ--AWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKP------LDIDECGEIP 1736
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQ--APCRNYAGGYRC 515
+ G C+N +GSFRC CP G+ ++ C D DEC ++ CQ A C N G YRC
Sbjct: 1737 AICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRC 1796
Query: 516 DCPVGTVRSPSG 551
C G SP G
Sbjct: 1797 KCTRGYKLSPGG 1808
Score = 70.5 bits (165), Expect = 4e-12
Identities = 56/185 (30%), Positives = 73/185 (39%), Gaps = 12/185 (6%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDE 182
N G FRC+C GY G +ECA P C + +C NT GSY C C +EL+
Sbjct: 1428 NLPGMFRCICNGGYELDRGGGNCTDINECA-DPVNCINGVCINTPGSYLCSCPQDFELNP 1486
Query: 183 DGANCRDV--DECERDTHTCQQICSNTEGSYECSCEDGYE-KRGDACVDINECHEEG--V 347
G C D C +TH + CS E G R C + +
Sbjct: 1487 SGVGCVDTRAGNCFLETH------DRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCEL 1540
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCV--DRDECAQT-GRCQA-PCRNYAGGYRC 515
CP +R +CP G + D DEC + G CQ C N G ++C
Sbjct: 1541 CPMANTT-----EYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQC 1595
Query: 516 DCPVG 530
+CP G
Sbjct: 1596 ECPPG 1600
Score = 59.3 bits (137), Expect = 9e-09
Identities = 58/201 (28%), Positives = 70/201 (34%), Gaps = 40/201 (19%)
Frame = +3
Query: 39 CGPGY-RPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDV-- 206
C G+ R G +EC P C C NT GS+ C C G LD G C DV
Sbjct: 862 CARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRL 921
Query: 207 DEC--ERDTHTCQQICSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCPS------ 356
+ C D C C C G + +AC D +CP
Sbjct: 922 EPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFAS 981
Query: 357 -------------------PGRCV-----NLLGSFRCVCPRGYRLDAEGARCVDRDEC-A 461
PG C N +GSF C C G+ LDA+ C D DEC
Sbjct: 982 RDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRI 1041
Query: 462 QTGRC-QAPCRNYAGGYRCDC 521
C Q C N G + C+C
Sbjct: 1042 SPDLCGQGTCVNTPGSFECEC 1062
Score = 53.6 bits (123), Expect = 4e-07
Identities = 30/80 (37%), Positives = 38/80 (47%), Gaps = 6/80 (7%)
Frame = +3
Query: 309 ACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD--RDECAQT---G 470
AC D++EC G+C G CVN++GSF C CP G+RL A C D C G
Sbjct: 251 ACQDVDECQAVPGLCQG-GSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGG 309
Query: 471 RCQAPCRNYAGGYRCDCPVG 530
RC + +C C G
Sbjct: 310 RCAGDLAGHYTRRQCCCDRG 329
Score = 52.0 bits (119), Expect = 1e-06
Identities = 26/72 (36%), Positives = 34/72 (47%)
Frame = +3
Query: 333 HEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYR 512
H +C + GRC+ S+RC C GY D G C+D DEC + C N G Y
Sbjct: 421 HFTNLCLN-GRCLPTPSSYRCECNVGYTQDVRG-ECIDVDECTSSPCHHGDCVNIPGTYH 478
Query: 513 CDCPVGTVRSPS 548
C C G +P+
Sbjct: 479 CRCYPGFQATPT 490
Score = 45.2 bits (102), Expect = 2e-04
Identities = 31/93 (33%), Positives = 42/93 (45%), Gaps = 8/93 (8%)
Frame = +3
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQ-QICSNTEGSYECSCEDGYEKRGDACVDINEC 332
CR G+ + C+DVDEC+ CQ C N GS+ C C G+ + E
Sbjct: 239 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAA--CED 296
Query: 333 HEEGVCPS---PGRCV-NLLGSF---RCVCPRG 410
+ G C S GRC +L G + +C C RG
Sbjct: 297 YRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRG 329
Score = 42.7 bits (96), Expect = 8e-04
Identities = 44/147 (29%), Positives = 54/147 (36%), Gaps = 5/147 (3%)
Frame = +3
Query: 105 PPCDQLCHNTD---GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYEC 275
P CD+ CHN G C C G+ +CERD T C G C
Sbjct: 156 PICDRGCHNGGRCIGPNRCACVYGFM----------GPQCERDYRTGP--CFGQVGPEGC 203
Query: 276 SCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE 455
++ G C C G + G L + C RG+ + C D DE
Sbjct: 204 Q----HQLTGLVCTKALCCATVG--RAWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDE 257
Query: 456 C-AQTGRCQ-APCRNYAGGYRCDCPVG 530
C A G CQ C N G + C CPVG
Sbjct: 258 CQAVPGLCQGGSCVNMVGSFHCRCPVG 284
Score = 41.9 bits (94), Expect = 0.001
Identities = 43/144 (29%), Positives = 50/144 (34%), Gaps = 6/144 (4%)
Frame = +3
Query: 3 RGVNTIGS-FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELD 179
+G N GS F C PG+R GR +C V P C + C S LC
Sbjct: 62 QGPNVCGSRFHAYCCPGWRT----FPGRSQCVV--PICRRACGEGFCSQPNLCTCA---- 111
Query: 180 EDGANCRDVDECERDTHTCQQICSN--TEGSYECSCEDGYEKRGDAC---VDINECHEEG 344
DG C C N T C C+ GY G C + CH G
Sbjct: 112 -DGTLAPSCGVSRGSG--CSVSCMNGGTCRGASCLCQKGYT--GTVCGQPICDRGCHNGG 166
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYR 416
C P RC + G C R YR
Sbjct: 167 RCIGPNRCACVYGFMGPQCERDYR 190
Score = 35.1 bits (77), Expect = 0.17
Identities = 16/41 (39%), Positives = 19/41 (46%), Gaps = 1/41 (2%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRD 203
DEC P C C N GS+ C C G+ L + A C D
Sbjct: 256 DECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 296
>AK131282-1|BAD18457.1| 872|Homo sapiens protein ( Homo sapiens cDNA
FLJ16233 fis, clone FEBRA2028256, moderately similar to
FIBRILLIN 2 PRECURSOR. ).
Length = 872
Score = 177 bits (431), Expect = 2e-44
Identities = 80/178 (44%), Positives = 102/178 (57%), Gaps = 4/178 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+N++GSFRC C GY P DEC+ P PC LC NT GS+ C C GY L+E
Sbjct: 486 INSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEE 545
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPG 362
DG C+D+DEC H CQ +C NT G++ C C G+ + AC D+NEC C
Sbjct: 546 DGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDVNECDGPHRCQH-- 603
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRC-QAPCRNYAGGYRCDCPVG 530
C N LG +RC CP+G+ ++ A+CVD +ECA C A CRN GG+RC CP G
Sbjct: 604 GCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSG 661
Score = 144 bits (349), Expect = 2e-34
Identities = 76/185 (41%), Positives = 88/185 (47%), Gaps = 5/185 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT GSF C C GY GR + DEC R C LC NT G++ C C G+
Sbjct: 528 NTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQ 587
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSP 359
C DV+EC+ H CQ C N G Y CSC G+ + CVD NEC
Sbjct: 588 A--CFDVNECD-GPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGS 644
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRCDCPVGTV 536
C N LG FRCVCP G+ D C D DECA + G C C N GG+ C CP G
Sbjct: 645 ASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYF 704
Query: 537 RSPSG 551
R+ G
Sbjct: 705 RAGQG 709
Score = 140 bits (340), Expect = 2e-33
Identities = 80/189 (42%), Positives = 98/189 (51%), Gaps = 9/189 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VNT GSFRC C GY G+ DEC+V P C N G ++C C G+E
Sbjct: 207 VNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGL 266
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINECHE-EGVCP 353
C D+DEC + C C NTEGSY C+C GY R D C D++EC + + C
Sbjct: 267 M-MTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCH 325
Query: 354 SPG-RCVNLLGSFRCVCPRGYR-LDAEGARCVDRDEC-AQTGRC-QAPCRNYAGGYRCDC 521
+ G C NL+G+F CVCP G R L G C D +EC AQ C C N AG +RCDC
Sbjct: 326 ARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDC 385
Query: 522 PVGTVRSPS 548
G SP+
Sbjct: 386 DEGFQPSPT 394
Score = 132 bits (320), Expect = 6e-31
Identities = 65/152 (42%), Positives = 77/152 (50%), Gaps = 7/152 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA-GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
N IG F C C G+ P DEC++ P C CHNT+GSY C C GY L EDG
Sbjct: 249 NVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDG 308
Query: 189 ANCRDVDEC---ERDTHTCQQICSNTEGSYECSCEDGYEK---RGDACVDINECHEEGVC 350
A CRDVDEC ++D H C N G++ C C G G+ C D NECH +
Sbjct: 309 AMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDL 368
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
GRCVN GSFRC C G++ C D
Sbjct: 369 CVNGRCVNTAGSFRCDCDEGFQPSPTLTECHD 400
Score = 131 bits (316), Expect = 2e-30
Identities = 69/170 (40%), Positives = 88/170 (51%), Gaps = 4/170 (2%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C G GY GR V DEC + C C N+ GS+ C C+ GY D C D+D
Sbjct: 457 CPHGSGYTAEGRDV---DECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMD 513
Query: 210 ECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINEC-HEEGVCPSPGRCVNLL 380
EC + C +C NT+GS+ CSC GY E+ G C D++EC + C CVN +
Sbjct: 514 ECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQF--LCVNTV 571
Query: 381 GSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
G+F C CP G+ + C D +EC RCQ C+N GGYRC CP G
Sbjct: 572 GAFTCRCPPGFTQHHQA--CFDVNECDGPHRCQHGCQNQLGGYRCSCPQG 619
Score = 127 bits (307), Expect = 2e-29
Identities = 69/156 (44%), Positives = 83/156 (53%), Gaps = 7/156 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNT 257
+ECA P C +C NTDGS+ C C GY LD G NC D DEC H C Q C+N
Sbjct: 192 NECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVG-HPCGQGTCTNV 250
Query: 258 EGSYECSCEDGYEK-RGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGA 434
G +EC+C DG+E C DI+EC + RC N GS+ C CP GY L +GA
Sbjct: 251 IGGFECACADGFEPGLMMTCEDIDECSLNPLL-CAFRCHNTEGSYLCTCPAGYTLREDGA 309
Query: 435 RCVDRDECAQTGR-CQA---PCRNYAGGYRCDCPVG 530
C D DECA + C A C+N G + C CP G
Sbjct: 310 MCRDVDECADGQQDCHARGMECKNLIGTFACVCPPG 345
Score = 105 bits (251), Expect = 1e-22
Identities = 69/215 (32%), Positives = 96/215 (44%), Gaps = 35/215 (16%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRP---AGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELD 179
N IG+F CVC PG RP +G G +EC +P C + C NT GS+ C C G++
Sbjct: 333 NLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPS 392
Query: 180 EDGANCRDVDE--CERDT--HTCQQICSNTEG--SYECSCED--GYEKRGDACV------ 317
C D+ + C + C+ + S++E EC C G+ R + C
Sbjct: 393 PTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSA 452
Query: 318 ----------------DINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR 449
D++EC + G C+N LGSFRC C GY DA C+D
Sbjct: 453 YRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDM 512
Query: 450 DECAQTGR-CQAPCRNYAGGYRCDCPVGTVRSPSG 551
DEC+Q + C C+N G + C CP G + G
Sbjct: 513 DECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDG 547
Score = 87.0 bits (206), Expect = 4e-17
Identities = 39/106 (36%), Positives = 55/106 (51%), Gaps = 4/106 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDE--CAVRPPPCDQL-CHNTDGSYDCLCRTGYELDE 182
N +G +RC C G+ + + DE CA+ PP C C NT G + C+C +G++ D+
Sbjct: 607 NQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQ 666
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CV 317
C+DVDEC C C+NT G + C C GY + G CV
Sbjct: 667 ALGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCV 712
Score = 85.0 bits (201), Expect = 2e-16
Identities = 67/213 (31%), Positives = 90/213 (42%), Gaps = 37/213 (17%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPC-----DQLCHNTDGS------YD 149
R VNT GSFRC C G++P+ D +R PC +C + S +
Sbjct: 373 RCVNTAGSFRCDCDEGFQPSPTLTECHD---IRQGPCFAEVLQTMCRSLSSSSEAVTRAE 429
Query: 150 CLCRTG------YELDEDGANCRDVDECE---------RDTHTCQ---QICSNTE----- 260
C C G EL C RD C+ +C++ E
Sbjct: 430 CCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSL 489
Query: 261 GSYECSCEDGY--EKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGA 434
GS+ C C+ GY + C+D++EC + P C N GSF C CPRGY L+ +G
Sbjct: 490 GSFRCHCQAGYTPDATATTCLDMDECSQVPK-PCTFLCKNTKGSFLCSCPRGYLLEEDGR 548
Query: 435 RCVDRDEC-AQTGRCQAPCRNYAGGYRCDCPVG 530
C D DEC ++ CQ C N G + C CP G
Sbjct: 549 TCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPG 581
Score = 81.0 bits (191), Expect = 3e-15
Identities = 40/77 (51%), Positives = 45/77 (58%), Gaps = 2/77 (2%)
Frame = +3
Query: 306 DACVDINECHEE-GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-Q 479
D+ D+NEC E GVC + G CVN GSFRC CP GY LD G CVD DEC+ C Q
Sbjct: 186 DSREDVNECAENPGVCTN-GVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQ 244
Query: 480 APCRNYAGGYRCDCPVG 530
C N GG+ C C G
Sbjct: 245 GTCTNVIGGFECACADG 261
>AF051345-1|AAC39880.2| 1624|Homo sapiens latent transforming growth
factor-beta binding protein 4L protein.
Length = 1624
Score = 168 bits (408), Expect = 1e-41
Identities = 84/187 (44%), Positives = 106/187 (56%), Gaps = 7/187 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
N+ GSFRCVCGPG+R R DEC PPPCD C NT GS+ C+C GY+
Sbjct: 605 NSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAP 664
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPS 356
GA+C+DVDEC + C + C N GS+ C C G+ RG AC D++EC +E
Sbjct: 665 HGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGF--RGSACEEDVDECAQEPPPCG 722
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQT-GRC-QAPCRNYAGGYRCDCPVG 530
PGRC N GSF C CP G+R GA C D DECA++ C C N G ++C CP+G
Sbjct: 723 PGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMG 782
Query: 531 TVRSPSG 551
+ +G
Sbjct: 783 FQPNAAG 789
Score = 145 bits (352), Expect = 8e-35
Identities = 73/188 (38%), Positives = 92/188 (48%), Gaps = 8/188 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGV--RGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
NT GSF C C G+R G G + DECA PPPC C NT+GS+ C+C G++ +
Sbjct: 728 NTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNA 787
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYEC-SCEDGYEKRGDACVDINECHEEG-VCPS 356
G+ C DVDECE Q C N+ GS++C +C G+ C D++EC C
Sbjct: 788 AGSECEDVDECENHLACPGQECVNSPGSFQCRACPSGHHLHRGRCTDVDECSSGAPPCGP 847
Query: 357 PGRCVNLLGSFRCVCPRGYRL-DAEGARCVDRDECAQTGRC--QAPCRNYAGGYRCDCPV 527
G C N GSFRC C GYR C D +EC + C C N G + C C
Sbjct: 848 HGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAP 907
Query: 528 GTVRSPSG 551
G P G
Sbjct: 908 GYRPGPRG 915
Score = 140 bits (340), Expect = 2e-33
Identities = 87/196 (44%), Positives = 104/196 (53%), Gaps = 16/196 (8%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR-PAGRGVRGRD--ECAVRPPPC--DQLCHNTDGSYDCLCRTGYEL 176
NT GSFRC C PGYR P+GR D EC + C C NTDGS+ C C GY
Sbjct: 853 NTEGSFRCSCAPGYRAPSGRPGPCADVNEC-LEGDFCFPHGECLNTDGSFACTCAPGYRP 911
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEG-- 344
GA+C DVDEC + IC+NT+GS+EC C G+ D +C+D++EC E G
Sbjct: 912 GPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPA 971
Query: 345 VCPSPGRCVNLLGSFRCV--CPRGYRLDAEGARCVDRDECAQTGR--CQAP-CRNYAGGY 509
+C S RC N GS+RCV C GY EG C D DEC + G C A C N G Y
Sbjct: 972 LCGSQ-RCENSPGSYRCVRDCDPGYHAGPEGT-CDDVDECQEYGPEICGAQRCENTPGSY 1029
Query: 510 RCD--CPVGTVRSPSG 551
RC C G +P G
Sbjct: 1030 RCTPACDPGYQPTPGG 1045
Score = 140 bits (338), Expect = 4e-33
Identities = 78/187 (41%), Positives = 98/187 (52%), Gaps = 13/187 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+NT GSF C C PGYRP RG DEC+ +C NTDGS++C+C G+
Sbjct: 895 LNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGP 954
Query: 183 DGANCRDVDEC-ERDTHTC-QQICSNTEGSYEC--SCEDGYEKRGD-ACVDINECHEEG- 344
D A+C DVDEC ER C Q C N+ GSY C C+ GY + C D++EC E G
Sbjct: 955 DLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGP 1014
Query: 345 -VCPSPGRCVNLLGSFRC--VCPRGYRLDAEGARCVDRDECAQTGRC--QAPCRNYAGGY 509
+C + RC N GS+RC C GY+ G C D DEC C A C+N G +
Sbjct: 1015 EICGAQ-RCENTPGSYRCTPACDPGYQ-PTPGGGCQDVDECRNRSFCGAHAVCQNLPGSF 1072
Query: 510 RCDCPVG 530
+C C G
Sbjct: 1073 QCLCDQG 1079
Score = 139 bits (336), Expect = 7e-33
Identities = 77/186 (41%), Positives = 97/186 (52%), Gaps = 10/186 (5%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYE 173
R ++ + C C G+R + +G R DEC PPPC C N+ GS+ C+C G+
Sbjct: 560 RCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFR 619
Query: 174 LDEDGANCRDVDECERDTHTCQ-QICSNTEGSYECSCEDGYE--KRGDACVDINECHEE- 341
A C DVDEC R C C NT GS+ C C GY+ G +C D++EC +
Sbjct: 620 AGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSP 679
Query: 342 GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQAP--CRNYAGGYR 512
G+C G C NL GSFRCVCP G+R G+ C D DECAQ P C N AG +
Sbjct: 680 GLC-GRGACKNLPGSFRCVCPAGFR----GSACEEDVDECAQEPPPCGPGRCDNTAGSFH 734
Query: 513 CDCPVG 530
C CP G
Sbjct: 735 CACPAG 740
Score = 137 bits (331), Expect = 3e-32
Identities = 78/184 (42%), Positives = 95/184 (51%), Gaps = 13/184 (7%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPP-C-DQLCHNTDGSYDCL--CRTGYE 173
NT GSF C+C PG+R P DEC R P C Q C N+ GSY C+ C GY
Sbjct: 937 NTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYH 996
Query: 174 LDEDGANCRDVDEC-ERDTHTC-QQICSNTEGSYECS--CEDGYEKR-GDACVDINECHE 338
+G C DVDEC E C Q C NT GSY C+ C+ GY+ G C D++EC
Sbjct: 997 AGPEGT-CDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRN 1055
Query: 339 EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQAP-CRNYAGGYR 512
C + C NL GSF+C+C +GY +G CVD +EC G C A C N G +
Sbjct: 1056 RSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFL 1115
Query: 513 CDCP 524
C CP
Sbjct: 1116 CVCP 1119
Score = 126 bits (305), Expect = 4e-29
Identities = 62/153 (40%), Positives = 76/153 (49%), Gaps = 6/153 (3%)
Frame = +3
Query: 90 CAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEG 263
C P C C + Y C C +G+ L G C DVDEC R C C N+ G
Sbjct: 549 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 608
Query: 264 SYECSCEDGYEK--RGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGAR 437
S+ C C G+ R C+D++ECH GRC N GSF CVCP GY+ GA
Sbjct: 609 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGAS 668
Query: 438 CVDRDECAQT-GRC-QAPCRNYAGGYRCDCPVG 530
C D DEC Q+ G C + C+N G +RC CP G
Sbjct: 669 CQDVDECTQSPGLCGRGACKNLPGSFRCVCPAG 701
Score = 84.6 bits (200), Expect = 2e-16
Identities = 44/101 (43%), Positives = 55/101 (54%), Gaps = 5/101 (4%)
Frame = +3
Query: 12 NTIGSFRCV--CGPGYRPA-GRGVRGRDECAVRP-PPCDQLCHNTDGSYDCLCRTGYELD 179
NT GS+RC C PGY+P G G + DEC R +C N GS+ CLC GYE
Sbjct: 1024 NTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGA 1083
Query: 180 EDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYEK 299
DG +C DV+ECE C +C N EGS+ C C + E+
Sbjct: 1084 RDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEE 1124
Score = 71.7 bits (168), Expect = 2e-12
Identities = 43/120 (35%), Positives = 54/120 (45%), Gaps = 8/120 (6%)
Frame = +3
Query: 117 QLCHNTD-GSYDCLCR--TGYELDEDGANCR-DVDECE--RDTHTCQQICSNTEGSYECS 278
Q C T+ Y LC GY + R DVDEC+ RD +C NT Y C
Sbjct: 1221 QQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCY 1280
Query: 279 CEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRD 452
C +GY C+D +EC +E GRCVN +GS+ C C LD RCV +
Sbjct: 1281 CSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNE 1340
Score = 66.9 bits (156), Expect = 4e-11
Identities = 46/162 (28%), Positives = 64/162 (39%), Gaps = 3/162 (1%)
Frame = +3
Query: 45 PGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECE-R 221
P P G G R P CD + +C C G + G+ CR + +C
Sbjct: 1171 PRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVG---EGWGSGCR-IQQCPGT 1226
Query: 222 DTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVC 401
+T Q +C + G S + + D C + + VC S G CVN + C C
Sbjct: 1227 ETAEYQSLCPHGRGYLAPSGDLSLRRDVDEC----QLFRDQVCKS-GVCVNTAPGYSCYC 1281
Query: 402 PRGYRLDAEGARCVDRDECA-QTGRCQ-APCRNYAGGYRCDC 521
GY + C+D DECA + C+ C N G Y C C
Sbjct: 1282 SNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTC 1323
Score = 61.7 bits (143), Expect = 2e-09
Identities = 28/69 (40%), Positives = 36/69 (52%), Gaps = 2/69 (2%)
Frame = +3
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRCD 518
VC PGRC++ + C C G+RL +G RC+D DEC + AP C N G +RC
Sbjct: 555 VC-GPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCV 613
Query: 519 CPVGTVRSP 545
C G P
Sbjct: 614 CGPGFRAGP 622
Score = 52.8 bits (121), Expect = 8e-07
Identities = 36/95 (37%), Positives = 45/95 (47%), Gaps = 5/95 (5%)
Frame = +3
Query: 261 GSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC 440
GSY S + YE+ ++ EC C + GRCV + F C C GYRLD C
Sbjct: 1519 GSYAGSLAEPYEE-----LEAEECGILDGCTN-GRCVRVPEGFTCRCFDGYRLDMTRMAC 1572
Query: 441 VDRDEC----AQTGRC-QAPCRNYAGGYRCDCPVG 530
VD +EC A + C A C N G +RC C G
Sbjct: 1573 VDINECDEAEAASPLCVNARCLNTDGSFRCICRPG 1607
Score = 51.6 bits (118), Expect = 2e-06
Identities = 27/61 (44%), Positives = 32/61 (52%), Gaps = 5/61 (8%)
Frame = +3
Query: 246 CSNTEGSYECSCEDGY--EKRGDACVDINECHE-EGVCPS--PGRCVNLLGSFRCVCPRG 410
C + C C DGY + ACVDINEC E E P RC+N GSFRC+C G
Sbjct: 1548 CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPG 1607
Query: 411 Y 413
+
Sbjct: 1608 F 1608
Score = 48.4 bits (110), Expect = 2e-05
Identities = 37/128 (28%), Positives = 51/128 (39%), Gaps = 3/128 (2%)
Frame = +3
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINE 329
C TG+E +C DVDEC C+NT G Y C C DG+ + +C+
Sbjct: 344 CPTGFE--RVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCIS--- 398
Query: 330 CHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAG-G 506
+ + + G C +L C P R + C R A CQ C + G
Sbjct: 399 --QHVISEAKGPCFRVLRDGGCSLPI-LRNITKQICCCSRVGKAWGRGCQL-CPPFGSEG 454
Query: 507 YRCDCPVG 530
+R CP G
Sbjct: 455 FREICPAG 462
Score = 46.8 bits (106), Expect = 5e-05
Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 4/74 (5%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDEC---ERDTHTCQQI-CS 251
+EC + + C + C C GY LD C D++EC E + C C
Sbjct: 1535 EECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCL 1594
Query: 252 NTEGSYECSCEDGY 293
NT+GS+ C C G+
Sbjct: 1595 NTDGSFRCICRPGF 1608
Score = 42.7 bits (96), Expect = 8e-04
Identities = 24/66 (36%), Positives = 28/66 (42%), Gaps = 3/66 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCD-QLCHNTDGSYDCLCRTGYELD 179
VNT + C C GY + + DECA P C+ C NT GSY C C LD
Sbjct: 1271 VNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLD 1330
Query: 180 EDGANC 197
C
Sbjct: 1331 GSQRRC 1336
Score = 38.3 bits (85), Expect = 0.018
Identities = 24/71 (33%), Positives = 30/71 (42%), Gaps = 6/71 (8%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR-----PAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRT 164
R V F C C GYR A + DE P C + C NTDGS+ C+CR
Sbjct: 1547 RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRP 1606
Query: 165 GYELDEDGANC 197
G+ +C
Sbjct: 1607 GFAPTHQPHHC 1617
Score = 36.7 bits (81), Expect = 0.054
Identities = 17/53 (32%), Positives = 22/53 (41%)
Frame = +3
Query: 39 CGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
C G+ DECA C NT G Y C+C G+ LD ++C
Sbjct: 344 CPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSC 396
>AF051344-1|AAC39879.2| 1557|Homo sapiens latent transforming growth
factor-beta binding protein 4S protein.
Length = 1557
Score = 168 bits (408), Expect = 1e-41
Identities = 84/187 (44%), Positives = 106/187 (56%), Gaps = 7/187 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
N+ GSFRCVCGPG+R R DEC PPPCD C NT GS+ C+C GY+
Sbjct: 538 NSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAP 597
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPS 356
GA+C+DVDEC + C + C N GS+ C C G+ RG AC D++EC +E
Sbjct: 598 HGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGF--RGSACEEDVDECAQEPPPCG 655
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQT-GRC-QAPCRNYAGGYRCDCPVG 530
PGRC N GSF C CP G+R GA C D DECA++ C C N G ++C CP+G
Sbjct: 656 PGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMG 715
Query: 531 TVRSPSG 551
+ +G
Sbjct: 716 FQPNAAG 722
Score = 145 bits (352), Expect = 8e-35
Identities = 73/188 (38%), Positives = 92/188 (48%), Gaps = 8/188 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGV--RGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
NT GSF C C G+R G G + DECA PPPC C NT+GS+ C+C G++ +
Sbjct: 661 NTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNA 720
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYEC-SCEDGYEKRGDACVDINECHEEG-VCPS 356
G+ C DVDECE Q C N+ GS++C +C G+ C D++EC C
Sbjct: 721 AGSECEDVDECENHLACPGQECVNSPGSFQCRACPSGHHLHRGRCTDVDECSSGAPPCGP 780
Query: 357 PGRCVNLLGSFRCVCPRGYRL-DAEGARCVDRDECAQTGRC--QAPCRNYAGGYRCDCPV 527
G C N GSFRC C GYR C D +EC + C C N G + C C
Sbjct: 781 HGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAP 840
Query: 528 GTVRSPSG 551
G P G
Sbjct: 841 GYRPGPRG 848
Score = 140 bits (340), Expect = 2e-33
Identities = 87/196 (44%), Positives = 104/196 (53%), Gaps = 16/196 (8%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR-PAGRGVRGRD--ECAVRPPPC--DQLCHNTDGSYDCLCRTGYEL 176
NT GSFRC C PGYR P+GR D EC + C C NTDGS+ C C GY
Sbjct: 786 NTEGSFRCSCAPGYRAPSGRPGPCADVNEC-LEGDFCFPHGECLNTDGSFACTCAPGYRP 844
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEG-- 344
GA+C DVDEC + IC+NT+GS+EC C G+ D +C+D++EC E G
Sbjct: 845 GPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPA 904
Query: 345 VCPSPGRCVNLLGSFRCV--CPRGYRLDAEGARCVDRDECAQTGR--CQAP-CRNYAGGY 509
+C S RC N GS+RCV C GY EG C D DEC + G C A C N G Y
Sbjct: 905 LCGSQ-RCENSPGSYRCVRDCDPGYHAGPEGT-CDDVDECQEYGPEICGAQRCENTPGSY 962
Query: 510 RCD--CPVGTVRSPSG 551
RC C G +P G
Sbjct: 963 RCTPACDPGYQPTPGG 978
Score = 140 bits (338), Expect = 4e-33
Identities = 78/187 (41%), Positives = 98/187 (52%), Gaps = 13/187 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+NT GSF C C PGYRP RG DEC+ +C NTDGS++C+C G+
Sbjct: 828 LNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGP 887
Query: 183 DGANCRDVDEC-ERDTHTC-QQICSNTEGSYEC--SCEDGYEKRGD-ACVDINECHEEG- 344
D A+C DVDEC ER C Q C N+ GSY C C+ GY + C D++EC E G
Sbjct: 888 DLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGP 947
Query: 345 -VCPSPGRCVNLLGSFRC--VCPRGYRLDAEGARCVDRDECAQTGRC--QAPCRNYAGGY 509
+C + RC N GS+RC C GY+ G C D DEC C A C+N G +
Sbjct: 948 EICGAQ-RCENTPGSYRCTPACDPGYQ-PTPGGGCQDVDECRNRSFCGAHAVCQNLPGSF 1005
Query: 510 RCDCPVG 530
+C C G
Sbjct: 1006 QCLCDQG 1012
Score = 139 bits (336), Expect = 7e-33
Identities = 77/186 (41%), Positives = 97/186 (52%), Gaps = 10/186 (5%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYE 173
R ++ + C C G+R + +G R DEC PPPC C N+ GS+ C+C G+
Sbjct: 493 RCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFR 552
Query: 174 LDEDGANCRDVDECERDTHTCQ-QICSNTEGSYECSCEDGYE--KRGDACVDINECHEE- 341
A C DVDEC R C C NT GS+ C C GY+ G +C D++EC +
Sbjct: 553 AGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSP 612
Query: 342 GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQAP--CRNYAGGYR 512
G+C G C NL GSFRCVCP G+R G+ C D DECAQ P C N AG +
Sbjct: 613 GLC-GRGACKNLPGSFRCVCPAGFR----GSACEEDVDECAQEPPPCGPGRCDNTAGSFH 667
Query: 513 CDCPVG 530
C CP G
Sbjct: 668 CACPAG 673
Score = 137 bits (331), Expect = 3e-32
Identities = 78/184 (42%), Positives = 95/184 (51%), Gaps = 13/184 (7%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPP-C-DQLCHNTDGSYDCL--CRTGYE 173
NT GSF C+C PG+R P DEC R P C Q C N+ GSY C+ C GY
Sbjct: 870 NTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYH 929
Query: 174 LDEDGANCRDVDEC-ERDTHTC-QQICSNTEGSYECS--CEDGYEKR-GDACVDINECHE 338
+G C DVDEC E C Q C NT GSY C+ C+ GY+ G C D++EC
Sbjct: 930 AGPEGT-CDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRN 988
Query: 339 EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQAP-CRNYAGGYR 512
C + C NL GSF+C+C +GY +G CVD +EC G C A C N G +
Sbjct: 989 RSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFL 1048
Query: 513 CDCP 524
C CP
Sbjct: 1049 CVCP 1052
Score = 126 bits (305), Expect = 4e-29
Identities = 62/153 (40%), Positives = 76/153 (49%), Gaps = 6/153 (3%)
Frame = +3
Query: 90 CAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEG 263
C P C C + Y C C +G+ L G C DVDEC R C C N+ G
Sbjct: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 541
Query: 264 SYECSCEDGYEK--RGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGAR 437
S+ C C G+ R C+D++ECH GRC N GSF CVCP GY+ GA
Sbjct: 542 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGAS 601
Query: 438 CVDRDECAQT-GRC-QAPCRNYAGGYRCDCPVG 530
C D DEC Q+ G C + C+N G +RC CP G
Sbjct: 602 CQDVDECTQSPGLCGRGACKNLPGSFRCVCPAG 634
Score = 84.6 bits (200), Expect = 2e-16
Identities = 44/101 (43%), Positives = 55/101 (54%), Gaps = 5/101 (4%)
Frame = +3
Query: 12 NTIGSFRCV--CGPGYRPA-GRGVRGRDECAVRP-PPCDQLCHNTDGSYDCLCRTGYELD 179
NT GS+RC C PGY+P G G + DEC R +C N GS+ CLC GYE
Sbjct: 957 NTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGA 1016
Query: 180 EDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYEK 299
DG +C DV+ECE C +C N EGS+ C C + E+
Sbjct: 1017 RDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEE 1057
Score = 71.7 bits (168), Expect = 2e-12
Identities = 43/120 (35%), Positives = 54/120 (45%), Gaps = 8/120 (6%)
Frame = +3
Query: 117 QLCHNTD-GSYDCLCR--TGYELDEDGANCR-DVDECE--RDTHTCQQICSNTEGSYECS 278
Q C T+ Y LC GY + R DVDEC+ RD +C NT Y C
Sbjct: 1154 QQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCY 1213
Query: 279 CEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRD 452
C +GY C+D +EC +E GRCVN +GS+ C C LD RCV +
Sbjct: 1214 CSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNE 1273
Score = 66.9 bits (156), Expect = 4e-11
Identities = 46/162 (28%), Positives = 64/162 (39%), Gaps = 3/162 (1%)
Frame = +3
Query: 45 PGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECE-R 221
P P G G R P CD + +C C G + G+ CR + +C
Sbjct: 1104 PRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVG---EGWGSGCR-IQQCPGT 1159
Query: 222 DTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVC 401
+T Q +C + G S + + D C + + VC S G CVN + C C
Sbjct: 1160 ETAEYQSLCPHGRGYLAPSGDLSLRRDVDEC----QLFRDQVCKS-GVCVNTAPGYSCYC 1214
Query: 402 PRGYRLDAEGARCVDRDECA-QTGRCQ-APCRNYAGGYRCDC 521
GY + C+D DECA + C+ C N G Y C C
Sbjct: 1215 SNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTC 1256
Score = 61.7 bits (143), Expect = 2e-09
Identities = 28/69 (40%), Positives = 36/69 (52%), Gaps = 2/69 (2%)
Frame = +3
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRCD 518
VC PGRC++ + C C G+RL +G RC+D DEC + AP C N G +RC
Sbjct: 488 VC-GPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCV 546
Query: 519 CPVGTVRSP 545
C G P
Sbjct: 547 CGPGFRAGP 555
Score = 52.8 bits (121), Expect = 8e-07
Identities = 36/95 (37%), Positives = 45/95 (47%), Gaps = 5/95 (5%)
Frame = +3
Query: 261 GSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC 440
GSY S + YE+ ++ EC C + GRCV + F C C GYRLD C
Sbjct: 1452 GSYAGSLAEPYEE-----LEAEECGILDGCTN-GRCVRVPEGFTCRCFDGYRLDMTRMAC 1505
Query: 441 VDRDEC----AQTGRC-QAPCRNYAGGYRCDCPVG 530
VD +EC A + C A C N G +RC C G
Sbjct: 1506 VDINECDEAEAASPLCVNARCLNTDGSFRCICRPG 1540
Score = 51.6 bits (118), Expect = 2e-06
Identities = 27/61 (44%), Positives = 32/61 (52%), Gaps = 5/61 (8%)
Frame = +3
Query: 246 CSNTEGSYECSCEDGY--EKRGDACVDINECHE-EGVCPS--PGRCVNLLGSFRCVCPRG 410
C + C C DGY + ACVDINEC E E P RC+N GSFRC+C G
Sbjct: 1481 CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPG 1540
Query: 411 Y 413
+
Sbjct: 1541 F 1541
Score = 48.4 bits (110), Expect = 2e-05
Identities = 37/128 (28%), Positives = 51/128 (39%), Gaps = 3/128 (2%)
Frame = +3
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINE 329
C TG+E +C DVDEC C+NT G Y C C DG+ + +C+
Sbjct: 277 CPTGFE--RVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCIS--- 331
Query: 330 CHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAG-G 506
+ + + G C +L C P R + C R A CQ C + G
Sbjct: 332 --QHVISEAKGPCFRVLRDGGCSLPI-LRNITKQICCCSRVGKAWGRGCQL-CPPFGSEG 387
Query: 507 YRCDCPVG 530
+R CP G
Sbjct: 388 FREICPAG 395
Score = 46.8 bits (106), Expect = 5e-05
Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 4/74 (5%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDEC---ERDTHTCQQI-CS 251
+EC + + C + C C GY LD C D++EC E + C C
Sbjct: 1468 EECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCL 1527
Query: 252 NTEGSYECSCEDGY 293
NT+GS+ C C G+
Sbjct: 1528 NTDGSFRCICRPGF 1541
Score = 42.7 bits (96), Expect = 8e-04
Identities = 24/66 (36%), Positives = 28/66 (42%), Gaps = 3/66 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCD-QLCHNTDGSYDCLCRTGYELD 179
VNT + C C GY + + DECA P C+ C NT GSY C C LD
Sbjct: 1204 VNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLD 1263
Query: 180 EDGANC 197
C
Sbjct: 1264 GSQRRC 1269
Score = 38.3 bits (85), Expect = 0.018
Identities = 24/71 (33%), Positives = 30/71 (42%), Gaps = 6/71 (8%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR-----PAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRT 164
R V F C C GYR A + DE P C + C NTDGS+ C+CR
Sbjct: 1480 RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRP 1539
Query: 165 GYELDEDGANC 197
G+ +C
Sbjct: 1540 GFAPTHQPHHC 1550
Score = 36.7 bits (81), Expect = 0.054
Identities = 17/53 (32%), Positives = 22/53 (41%)
Frame = +3
Query: 39 CGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
C G+ DECA C NT G Y C+C G+ LD ++C
Sbjct: 277 CPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSC 329
>Y13622-1|CAA73944.1| 1587|Homo sapiens latent TGF-beta binding
protein-4 protein.
Length = 1587
Score = 167 bits (405), Expect = 3e-41
Identities = 84/187 (44%), Positives = 106/187 (56%), Gaps = 7/187 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
N+ GSFRCVCGPG+R R DEC PPPCD C NT GS+ C+C GY+
Sbjct: 568 NSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAP 627
Query: 183 DGANCRDVDECERDTHTCQQI-CSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPS 356
GA+C+DVDEC + C + C N GS+ C C G+ RG AC D++EC +E
Sbjct: 628 HGASCQDVDECTQSPGLCGRGGCKNLPGSFRCVCPAGF--RGSACEEDVDECAQEPPPCG 685
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQT-GRC-QAPCRNYAGGYRCDCPVG 530
PGRC N GSF C CP G+R GA C D DECA++ C C N G ++C CP+G
Sbjct: 686 PGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMG 745
Query: 531 TVRSPSG 551
+ +G
Sbjct: 746 FQPNTAG 752
Score = 145 bits (352), Expect = 8e-35
Identities = 73/188 (38%), Positives = 92/188 (48%), Gaps = 8/188 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGV--RGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
NT GSF C C G+R G G + DECA PPPC C NT+GS+ C+C G++ +
Sbjct: 691 NTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNT 750
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYEC-SCEDGYEKRGDACVDINECHEEG-VCPS 356
G+ C DVDECE Q C N+ GS++C +C G+ C D++EC C
Sbjct: 751 AGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGP 810
Query: 357 PGRCVNLLGSFRCVCPRGYRL-DAEGARCVDRDECAQTGRC--QAPCRNYAGGYRCDCPV 527
G C N GSFRC C GYR C D +EC + C C N G + C C
Sbjct: 811 HGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAP 870
Query: 528 GTVRSPSG 551
G P G
Sbjct: 871 GYRPGPRG 878
Score = 140 bits (340), Expect = 2e-33
Identities = 87/196 (44%), Positives = 104/196 (53%), Gaps = 16/196 (8%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR-PAGRGVRGRD--ECAVRPPPC--DQLCHNTDGSYDCLCRTGYEL 176
NT GSFRC C PGYR P+GR D EC + C C NTDGS+ C C GY
Sbjct: 816 NTEGSFRCSCAPGYRAPSGRPGPCADVNEC-LEGDFCFPHGECLNTDGSFACTCAPGYRP 874
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEG-- 344
GA+C DVDEC + IC+NT+GS+EC C G+ D +C+D++EC E G
Sbjct: 875 GPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPA 934
Query: 345 VCPSPGRCVNLLGSFRCV--CPRGYRLDAEGARCVDRDECAQTGR--CQAP-CRNYAGGY 509
+C S RC N GS+RCV C GY EG C D DEC + G C A C N G Y
Sbjct: 935 LCGSQ-RCENSPGSYRCVRDCDPGYHAGPEGT-CDDVDECQEYGPEICGAQRCENTPGSY 992
Query: 510 RCD--CPVGTVRSPSG 551
RC C G +P G
Sbjct: 993 RCTPACDPGYQPTPGG 1008
Score = 140 bits (338), Expect = 4e-33
Identities = 78/187 (41%), Positives = 98/187 (52%), Gaps = 13/187 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+NT GSF C C PGYRP RG DEC+ +C NTDGS++C+C G+
Sbjct: 858 LNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGP 917
Query: 183 DGANCRDVDEC-ERDTHTC-QQICSNTEGSYEC--SCEDGYEKRGD-ACVDINECHEEG- 344
D A+C DVDEC ER C Q C N+ GSY C C+ GY + C D++EC E G
Sbjct: 918 DLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGP 977
Query: 345 -VCPSPGRCVNLLGSFRC--VCPRGYRLDAEGARCVDRDECAQTGRC--QAPCRNYAGGY 509
+C + RC N GS+RC C GY+ G C D DEC C A C+N G +
Sbjct: 978 EICGAQ-RCENTPGSYRCTPACDPGYQ-PTPGGGCQDVDECRNRSFCGAHAVCQNLPGSF 1035
Query: 510 RCDCPVG 530
+C C G
Sbjct: 1036 QCLCDQG 1042
Score = 138 bits (335), Expect = 9e-33
Identities = 77/186 (41%), Positives = 97/186 (52%), Gaps = 10/186 (5%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYE 173
R ++ + C C G+R + +G R DEC PPPC C N+ GS+ C+C G+
Sbjct: 523 RCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFR 582
Query: 174 LDEDGANCRDVDECERDTHTCQ-QICSNTEGSYECSCEDGYE--KRGDACVDINECHEE- 341
A C DVDEC R C C NT GS+ C C GY+ G +C D++EC +
Sbjct: 583 AGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSP 642
Query: 342 GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQAP--CRNYAGGYR 512
G+C G C NL GSFRCVCP G+R G+ C D DECAQ P C N AG +
Sbjct: 643 GLC-GRGGCKNLPGSFRCVCPAGFR----GSACEEDVDECAQEPPPCGPGRCDNTAGSFH 697
Query: 513 CDCPVG 530
C CP G
Sbjct: 698 CACPAG 703
Score = 137 bits (331), Expect = 3e-32
Identities = 78/184 (42%), Positives = 95/184 (51%), Gaps = 13/184 (7%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPP-C-DQLCHNTDGSYDCL--CRTGYE 173
NT GSF C+C PG+R P DEC R P C Q C N+ GSY C+ C GY
Sbjct: 900 NTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYH 959
Query: 174 LDEDGANCRDVDEC-ERDTHTC-QQICSNTEGSYECS--CEDGYEKR-GDACVDINECHE 338
+G C DVDEC E C Q C NT GSY C+ C+ GY+ G C D++EC
Sbjct: 960 AGPEGT-CDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRN 1018
Query: 339 EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQAP-CRNYAGGYR 512
C + C NL GSF+C+C +GY +G CVD +EC G C A C N G +
Sbjct: 1019 RSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFL 1078
Query: 513 CDCP 524
C CP
Sbjct: 1079 CVCP 1082
Score = 126 bits (304), Expect = 5e-29
Identities = 62/153 (40%), Positives = 76/153 (49%), Gaps = 6/153 (3%)
Frame = +3
Query: 90 CAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEG 263
C P C C + Y C C +G+ L G C DVDEC R C C N+ G
Sbjct: 512 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 571
Query: 264 SYECSCEDGYEK--RGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGAR 437
S+ C C G+ R C+D++ECH GRC N GSF CVCP GY+ GA
Sbjct: 572 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGAS 631
Query: 438 CVDRDECAQT-GRC-QAPCRNYAGGYRCDCPVG 530
C D DEC Q+ G C + C+N G +RC CP G
Sbjct: 632 CQDVDECTQSPGLCGRGGCKNLPGSFRCVCPAG 664
Score = 84.6 bits (200), Expect = 2e-16
Identities = 44/101 (43%), Positives = 55/101 (54%), Gaps = 5/101 (4%)
Frame = +3
Query: 12 NTIGSFRCV--CGPGYRPA-GRGVRGRDECAVRP-PPCDQLCHNTDGSYDCLCRTGYELD 179
NT GS+RC C PGY+P G G + DEC R +C N GS+ CLC GYE
Sbjct: 987 NTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGA 1046
Query: 180 EDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYEK 299
DG +C DV+ECE C +C N EGS+ C C + E+
Sbjct: 1047 RDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEE 1087
Score = 71.7 bits (168), Expect = 2e-12
Identities = 43/120 (35%), Positives = 54/120 (45%), Gaps = 8/120 (6%)
Frame = +3
Query: 117 QLCHNTD-GSYDCLCR--TGYELDEDGANCR-DVDECE--RDTHTCQQICSNTEGSYECS 278
Q C T+ Y LC GY + R DVDEC+ RD +C NT Y C
Sbjct: 1184 QQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCY 1243
Query: 279 CEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRD 452
C +GY C+D +EC +E GRCVN +GS+ C C LD RCV +
Sbjct: 1244 CSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNE 1303
Score = 67.3 bits (157), Expect = 3e-11
Identities = 46/162 (28%), Positives = 64/162 (39%), Gaps = 3/162 (1%)
Frame = +3
Query: 45 PGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECE-R 221
P P G G R P CD + +C C G + G+ CR + +C
Sbjct: 1134 PRKGPVGSGCRECYFDTAAPDACDNILARNVTWQECCCTVG---EGWGSGCR-IQQCPGT 1189
Query: 222 DTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVC 401
+T Q +C + G S + + D C + + VC S G CVN + C C
Sbjct: 1190 ETAEYQSLCPHGRGYLAPSGDLSLRRDVDEC----QLFRDQVCKS-GVCVNTAPGYSCYC 1244
Query: 402 PRGYRLDAEGARCVDRDECA-QTGRCQ-APCRNYAGGYRCDC 521
GY + C+D DECA + C+ C N G Y C C
Sbjct: 1245 SNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTC 1286
Score = 61.7 bits (143), Expect = 2e-09
Identities = 28/69 (40%), Positives = 36/69 (52%), Gaps = 2/69 (2%)
Frame = +3
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRCD 518
VC PGRC++ + C C G+RL +G RC+D DEC + AP C N G +RC
Sbjct: 518 VC-GPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCV 576
Query: 519 CPVGTVRSP 545
C G P
Sbjct: 577 CGPGFRAGP 585
Score = 54.4 bits (125), Expect = 3e-07
Identities = 36/97 (37%), Positives = 44/97 (45%), Gaps = 5/97 (5%)
Frame = +3
Query: 138 GSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDA 311
GSY YE + + C +D C D C + C C DGY + A
Sbjct: 1482 GSYAGSLAEPYE-ELEAEECGILDGCTNDR------CVRVPEGFTCRCFDGYRLDMTRMA 1534
Query: 312 CVDINECHE-EGVCPS--PGRCVNLLGSFRCVCPRGY 413
CVDINEC E E P RC+N GSFRC+C G+
Sbjct: 1535 CVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGF 1571
Score = 50.0 bits (114), Expect = 5e-06
Identities = 35/95 (36%), Positives = 44/95 (46%), Gaps = 5/95 (5%)
Frame = +3
Query: 261 GSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC 440
GSY S + YE+ ++ EC C + RCV + F C C GYRLD C
Sbjct: 1482 GSYAGSLAEPYEE-----LEAEECGILDGCTND-RCVRVPEGFTCRCFDGYRLDMTRMAC 1535
Query: 441 VDRDEC----AQTGRC-QAPCRNYAGGYRCDCPVG 530
VD +EC A + C A C N G +RC C G
Sbjct: 1536 VDINECDEAEAASPLCVNARCLNTDGSFRCICRPG 1570
Score = 48.4 bits (110), Expect = 2e-05
Identities = 37/128 (28%), Positives = 51/128 (39%), Gaps = 3/128 (2%)
Frame = +3
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINE 329
C TG+E +C DVDEC C+NT G Y C C DG+ + +C+
Sbjct: 307 CPTGFE--RVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCIS--- 361
Query: 330 CHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAG-G 506
+ + + G C +L C P R + C R A CQ C + G
Sbjct: 362 --QHVISEAKGPCFRVLRDGGCSLPI-LRNITKQICCCSRVGKAWGRGCQL-CPPFGSEG 417
Query: 507 YRCDCPVG 530
+R CP G
Sbjct: 418 FREICPAG 425
Score = 47.6 bits (108), Expect = 3e-05
Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 4/74 (5%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDEC---ERDTHTCQQI-CS 251
+EC + + C + C C GY LD C D++EC E + C C
Sbjct: 1498 EECGILDGCTNDRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCL 1557
Query: 252 NTEGSYECSCEDGY 293
NT+GS+ C C G+
Sbjct: 1558 NTDGSFRCICRPGF 1571
Score = 42.7 bits (96), Expect = 8e-04
Identities = 24/66 (36%), Positives = 28/66 (42%), Gaps = 3/66 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCD-QLCHNTDGSYDCLCRTGYELD 179
VNT + C C GY + + DECA P C+ C NT GSY C C LD
Sbjct: 1234 VNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLD 1293
Query: 180 EDGANC 197
C
Sbjct: 1294 GSQRRC 1299
Score = 38.3 bits (85), Expect = 0.018
Identities = 24/71 (33%), Positives = 30/71 (42%), Gaps = 6/71 (8%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR-----PAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRT 164
R V F C C GYR A + DE P C + C NTDGS+ C+CR
Sbjct: 1510 RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRP 1569
Query: 165 GYELDEDGANC 197
G+ +C
Sbjct: 1570 GFAPTHQPHHC 1580
Score = 36.7 bits (81), Expect = 0.054
Identities = 17/53 (32%), Positives = 22/53 (41%)
Frame = +3
Query: 39 CGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
C G+ DECA C NT G Y C+C G+ LD ++C
Sbjct: 307 CPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSC 359
Score = 29.9 bits (64), Expect = 6.2
Identities = 33/118 (27%), Positives = 42/118 (35%), Gaps = 3/118 (2%)
Frame = +3
Query: 186 GANCRDVDECERDT---HTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPS 356
G+ CR EC DT C I + EC C G E G C I +C
Sbjct: 1140 GSGCR---ECYFDTAAPDACDNILARNVTWQECCCTVG-EGWGSGC-RIQQCPGTETAEY 1194
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
C + G R D + + RD+ ++G C N A GY C C G
Sbjct: 1195 QSLCPHGRGYLAPSGDLSLRRDVDECQLF-RDQVCKSGVCV----NTAPGYSCYCSNG 1247
>M34057-1|AAA61160.1| 1394|Homo sapiens TGFB1 protein.
Length = 1394
Score = 162 bits (394), Expect = 6e-40
Identities = 77/179 (43%), Positives = 98/179 (54%), Gaps = 6/179 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT GSFRC CG GY+ A DEC R C NT+GS+ C+C GY
Sbjct: 769 NTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGL 828
Query: 186 GANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD-ACVDINECHEEGVCPSP 359
G +C D++EC D CQ+ C NT GSY+C+C DG++ + C DINEC G+C
Sbjct: 829 GDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQ 888
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRCDCPVG 530
G C+N GSF CVC +G+ + A+G C D DEC C + C N AG +RC C G
Sbjct: 889 GECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQG 947
Score = 148 bits (359), Expect = 1e-35
Identities = 79/179 (44%), Positives = 100/179 (55%), Gaps = 9/179 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQL-CHNTDGSYDCLCRTGYELDE 182
NT GSF+CVC GYR +G G D EC C + C NT GSYDC C G++LD
Sbjct: 810 NTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLD- 868
Query: 183 DGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVC 350
D C+D++ECE C Q C NTEGS+ C C+ G+ D C DI+EC VC
Sbjct: 869 DNKTCQDINECEHPG-LCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVC 927
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC-QAPCRNYAGGYRCDC 521
S G C N GSFRC+C +G++ +G CVD +EC +G C +A C N G + C C
Sbjct: 928 DSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVC 986
Score = 144 bits (349), Expect = 2e-34
Identities = 75/180 (41%), Positives = 97/180 (53%), Gaps = 6/180 (3%)
Frame = +3
Query: 9 VNTIGSFRCV-CGPGYRPAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDE 182
VN+ GS++CV C G+R DEC + P C + C N +GSY C C GY
Sbjct: 687 VNSPGSYQCVPCTEGFRGWNGQCLDVDEC-LEPNVCANGDCSNLEGSYMCSCHKGYTRTP 745
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRG--DACVDINECHEEGVCPS 356
D +CRD+DEC++ C NTEGS+ C+C GY+ D C DI+EC +C +
Sbjct: 746 DHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLC-A 804
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGRCQ-APCRNYAGGYRCDCPVG 530
G+C N GSF+CVC +GYR G C D +EC + CQ C N AG Y C CP G
Sbjct: 805 HGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDG 864
Score = 142 bits (344), Expect = 7e-34
Identities = 74/187 (39%), Positives = 93/187 (49%), Gaps = 7/187 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
N GS+ C C GY P + R DEC + C NT+GS+ C C GY+L
Sbjct: 728 NLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAA 787
Query: 186 GANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRG--DACVDINECHEEGVCPS 356
C D+DEC+ H C C NTEGS++C C+ GY G D C DINEC E+
Sbjct: 788 KDQCEDIDECQH-RHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQ 846
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC--QAPCRNYAGGYRCDCPVG 530
G C+N GS+ C CP G++LD + C D +EC G C Q C N G + C C G
Sbjct: 847 RGDCINTAGSYDCTCPDGFQLD-DNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQG 905
Query: 531 TVRSPSG 551
S G
Sbjct: 906 FSISADG 912
Score = 130 bits (313), Expect = 4e-30
Identities = 72/187 (38%), Positives = 94/187 (50%), Gaps = 8/187 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD 179
+N + C+C GYR R DEC C Q C NT+GS+ C+C G+
Sbjct: 563 INLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMAS 622
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECS-CEDGYE--KRGDACVDINECHEEGVC 350
E+G NC DVDEC R + C NT G++ C C+ GY +RG C DI+EC C
Sbjct: 623 EEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRG-RCEDIDECLNPSTC 681
Query: 351 PSPGRCVNLLGSFRCV-CPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCP 524
P +CVN GS++CV C G+R +C+D DEC + C C N G Y C C
Sbjct: 682 PDE-QCVNSPGSYQCVPCTEGFR--GWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCH 738
Query: 525 VGTVRSP 545
G R+P
Sbjct: 739 KGYTRTP 745
Score = 123 bits (297), Expect = 4e-28
Identities = 62/150 (41%), Positives = 76/150 (50%), Gaps = 6/150 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNT 257
+EC V P C C N Y C+C GY E C D+DEC + H C Q C NT
Sbjct: 548 NECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENT 607
Query: 258 EGSYECSCEDGY--EKRGDACVDINECHEEGVCPSPGRCVNLLGSFRC-VCPRGYRLDAE 428
EGS+ C C G+ + G C+D++EC VC G CVN +G+FRC C GYR+
Sbjct: 608 EGSFLCICPAGFMASEEGTNCIDVDECLRPDVC-GEGHCVNTVGAFRCEYCDSGYRMTQR 666
Query: 429 GARCVDRDECAQTGRC-QAPCRNYAGGYRC 515
G RC D DEC C C N G Y+C
Sbjct: 667 G-RCEDIDECLNPSTCPDEQCVNSPGSYQC 695
Score = 106 bits (254), Expect = 6e-23
Identities = 54/139 (38%), Positives = 75/139 (53%), Gaps = 8/139 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR-PAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELD 179
+NT GS+ C C G++ + + +EC P C C NT+GS+ C+C+ G+ +
Sbjct: 851 INTAGSYDCTCPDGFQLDDNKTCQDINECE-HPGLCGPQGECLNTEGSFHCVCQQGFSIS 909
Query: 180 EDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE--KRGDACVDINECH-EEG 344
DG C D+DEC +T C C NT GS+ C C G++ + G CVD+NEC G
Sbjct: 910 ADGRTCEDIDECVNNT-VCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSG 968
Query: 345 VCPSPGRCVNLLGSFRCVC 401
VC C N+ GSF CVC
Sbjct: 969 VC-GEAFCENVEGSFLCVC 986
Score = 86.2 bits (204), Expect = 7e-17
Identities = 43/115 (37%), Positives = 59/115 (51%), Gaps = 5/115 (4%)
Frame = +3
Query: 201 DVDECERDTHTCQQ-ICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPSPGRCV 371
+++EC + C C N Y C C +GY ++ CVDI+EC + S GRC
Sbjct: 546 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 605
Query: 372 NLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCD-CPVG 530
N GSF C+CP G+ EG C+D DEC + C + C N G +RC+ C G
Sbjct: 606 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSG 660
Score = 84.2 bits (199), Expect = 3e-16
Identities = 43/98 (43%), Positives = 54/98 (55%), Gaps = 5/98 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYEL 176
+NT GSF CVC G+ + GR DEC V CD C NT GS+ CLC G++
Sbjct: 892 LNTEGSFHCVCQQGFSISADGRTCEDIDEC-VNNTVCDSHGFCDNTAGSFRCLCYQGFQA 950
Query: 177 DEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCED 287
+DG C DV+ECE + C + C N EGS+ C C D
Sbjct: 951 PQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCAD 988
Score = 66.1 bits (154), Expect = 8e-11
Identities = 31/80 (38%), Positives = 39/80 (48%), Gaps = 2/80 (2%)
Frame = +3
Query: 318 DINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-C-QAPCR 491
+INEC G C+NL + C+C GYR + +CVD DEC Q C Q C
Sbjct: 546 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 605
Query: 492 NYAGGYRCDCPVGTVRSPSG 551
N G + C CP G + S G
Sbjct: 606 NTEGSFLCICPAGFMASEEG 625
Score = 64.5 bits (150), Expect = 2e-10
Identities = 34/90 (37%), Positives = 44/90 (48%), Gaps = 4/90 (4%)
Frame = +3
Query: 186 GANCRDVDECER-DTHTCQQ-ICSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCP 353
G N +D DEC C+ C NT YEC C+ G Y+ C D++EC + C
Sbjct: 1092 GENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCI 1151
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCV 443
G+CVN GS+ C C LDA RC+
Sbjct: 1152 D-GQCVNTEGSYNCFCTHPMVLDASEKRCI 1180
Score = 58.8 bits (136), Expect = 1e-08
Identities = 31/85 (36%), Positives = 45/85 (52%), Gaps = 2/85 (2%)
Frame = +3
Query: 279 CEDGYEKRGDA-CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE 455
C GY++ + C DINEC +GVCP+ G C+N +GS+RC C G+ D + CV
Sbjct: 286 CLPGYKRVNNTFCQDINECQLQGVCPN-GECLNTMGSYRCTCKIGFGPDPTFSSCVPDPP 344
Query: 456 CAQTGRCQAPC-RNYAGGYRCDCPV 527
+ PC R + G +C P+
Sbjct: 345 VISEEK--GPCYRLVSSGRQCMYPL 367
Score = 58.8 bits (136), Expect = 1e-08
Identities = 60/205 (29%), Positives = 79/205 (38%), Gaps = 27/205 (13%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLC-------- 158
NT GSFRC+C G++ G+G +EC + C + C N +GS+ C+C
Sbjct: 935 NTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYS 994
Query: 159 --------RTGYELDEDGANCRDVD-ECE---RDTHTCQQICSNTEGSYECSCEDGYEKR 302
RT +LD D ++ EC D C + + EC C G
Sbjct: 995 PMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSG-AGW 1053
Query: 303 GDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRL-DAEGARCVDRDECAQTGR-- 473
GD C +I C G C G P G +A G D DEC G+
Sbjct: 1054 GDNC-EIFPCPVLGTAEFTEMCPKGKG----FVPAGESSSEAGGENYKDADECLLFGQEI 1108
Query: 474 CQAP-CRNYAGGYRCDCPVGTVRSP 545
C+ C N GY C C GT P
Sbjct: 1109 CKNGFCLNTRPGYECYCKQGTYYDP 1133
Score = 56.4 bits (130), Expect = 6e-08
Identities = 40/118 (33%), Positives = 49/118 (41%), Gaps = 15/118 (12%)
Frame = +3
Query: 33 CVCGPGYRPAGRG--------VRGRDECAVRPPP-CDQ-LCHNTDGSYDCLCRTGYELDE 182
C G G+ PAG + DEC + C C NT Y+C C+ G D
Sbjct: 1074 CPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDP 1133
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCE-----DGYEKRGDACVDINECHEE 341
C D+DEC+ + C NTEGSY C C D EKR + NE EE
Sbjct: 1134 VKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEE 1191
Score = 54.0 bits (124), Expect = 3e-07
Identities = 39/141 (27%), Positives = 55/141 (39%), Gaps = 4/141 (2%)
Frame = +3
Query: 111 CDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECE-RDTHTCQQICSNTEGSYECSCED 287
CD + +C C +G G NC ++ C T ++C +G E
Sbjct: 1032 CDNVLAPNVTKQECCCTSGAGW---GDNC-EIFPCPVLGTAEFTEMCPKGKGFVPAG-ES 1086
Query: 288 GYEKRGDACVDINECHEEG--VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA 461
E G+ D +EC G +C + G C+N + C C +G D +C D DEC
Sbjct: 1087 SSEAGGENYKDADECLLFGQEICKN-GFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQ 1145
Query: 462 QTGRC-QAPCRNYAGGYRCDC 521
C C N G Y C C
Sbjct: 1146 DPSSCIDGQCVNTEGSYNCFC 1166
Score = 51.2 bits (117), Expect = 2e-06
Identities = 28/87 (32%), Positives = 40/87 (45%), Gaps = 6/87 (6%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTH---TCQQI-CS 251
+EC + + C Y C C GY LD C DV+EC+ + C+ C
Sbjct: 1296 EECGILNGCENGRCVRVQEGYTCDCLDGYHLDTAKMTCFDVNECDELNNRMSLCKNAKCI 1355
Query: 252 NTEGSYECSCEDGY--EKRGDACVDIN 326
NT+GSY+C C GY + + C +N
Sbjct: 1356 NTDGSYKCLCLPGYVPSDKPNYCTPLN 1382
Score = 47.2 bits (107), Expect = 4e-05
Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 6/62 (9%)
Frame = +3
Query: 246 CSNTEGSYECSCEDGY--EKRGDACVDINECHE----EGVCPSPGRCVNLLGSFRCVCPR 407
C + Y C C DGY + C D+NEC E +C + +C+N GS++C+C
Sbjct: 1309 CVRVQEGYTCDCLDGYHLDTAKMTCFDVNECDELNNRMSLCKN-AKCINTDGSYKCLCLP 1367
Query: 408 GY 413
GY
Sbjct: 1368 GY 1369
Score = 46.0 bits (104), Expect = 9e-05
Identities = 28/77 (36%), Positives = 35/77 (45%), Gaps = 5/77 (6%)
Frame = +3
Query: 327 ECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR----CQ-APCR 491
EC C + GRCV + + C C GY LD C D +EC + C+ A C
Sbjct: 1297 ECGILNGCEN-GRCVRVQEGYTCDCLDGYHLDTAKMTCFDVNECDELNNRMSLCKNAKCI 1355
Query: 492 NYAGGYRCDCPVGTVRS 542
N G Y+C C G V S
Sbjct: 1356 NTDGSYKCLCLPGYVPS 1372
Score = 35.5 bits (78), Expect = 0.12
Identities = 18/51 (35%), Positives = 22/51 (43%), Gaps = 1/51 (1%)
Frame = +3
Query: 399 CPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPVGTVRSPS 548
C GY+ C D +EC G C C N G YRC C +G P+
Sbjct: 286 CLPGYKR-VNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPT 335
Score = 35.1 bits (77), Expect = 0.17
Identities = 34/136 (25%), Positives = 55/136 (40%), Gaps = 5/136 (3%)
Frame = +3
Query: 39 CGPGYRPAGRGV-RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-RDVDE 212
C PGY+ + +EC ++ + C NT GSY C C+ G+ D ++C D
Sbjct: 286 CLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPV 345
Query: 213 CERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDACVDINEC--HEEGVCPSPGRCVNLLG 383
+ C + + S + Y S + + C + + H E CP PG
Sbjct: 346 ISEEKGPCYRLVSSGRQCMYPLSV---HLTKQLCCCSVGKAGPHCE-KCPLPG-----TA 396
Query: 384 SFRCVCPRGYRLDAEG 431
+F+ +CP G G
Sbjct: 397 AFKEICPGGMGYTVSG 412
Score = 31.1 bits (67), Expect = 2.7
Identities = 10/20 (50%), Positives = 16/20 (80%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGR 68
+NT GS++C+C PGY P+ +
Sbjct: 1355 INTDGSYKCLCLPGYVPSDK 1374
>BC130289-1|AAI30290.1| 1395|Homo sapiens latent transforming growth
factor beta binding protein 1 protein.
Length = 1395
Score = 162 bits (394), Expect = 6e-40
Identities = 77/179 (43%), Positives = 98/179 (54%), Gaps = 6/179 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT GSFRC CG GY+ A DEC R C NT+GS+ C+C GY
Sbjct: 770 NTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGL 829
Query: 186 GANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD-ACVDINECHEEGVCPSP 359
G +C D++EC D CQ+ C NT GSY+C+C DG++ + C DINEC G+C
Sbjct: 830 GDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQ 889
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRCDCPVG 530
G C+N GSF CVC +G+ + A+G C D DEC C + C N AG +RC C G
Sbjct: 890 GECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQG 948
Score = 148 bits (359), Expect = 1e-35
Identities = 79/179 (44%), Positives = 100/179 (55%), Gaps = 9/179 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQL-CHNTDGSYDCLCRTGYELDE 182
NT GSF+CVC GYR +G G D EC C + C NT GSYDC C G++LD
Sbjct: 811 NTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLD- 869
Query: 183 DGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVC 350
D C+D++ECE C Q C NTEGS+ C C+ G+ D C DI+EC VC
Sbjct: 870 DNKTCQDINECEHPG-LCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVC 928
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC-QAPCRNYAGGYRCDC 521
S G C N GSFRC+C +G++ +G CVD +EC +G C +A C N G + C C
Sbjct: 929 DSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVC 987
Score = 144 bits (349), Expect = 2e-34
Identities = 75/180 (41%), Positives = 97/180 (53%), Gaps = 6/180 (3%)
Frame = +3
Query: 9 VNTIGSFRCV-CGPGYRPAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDE 182
VN+ GS++CV C G+R DEC + P C + C N +GSY C C GY
Sbjct: 688 VNSPGSYQCVPCTEGFRGWNGQCLDVDEC-LEPNVCANGDCSNLEGSYMCSCHKGYTRTP 746
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRG--DACVDINECHEEGVCPS 356
D +CRD+DEC++ C NTEGS+ C+C GY+ D C DI+EC +C +
Sbjct: 747 DHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLC-A 805
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGRCQ-APCRNYAGGYRCDCPVG 530
G+C N GSF+CVC +GYR G C D +EC + CQ C N AG Y C CP G
Sbjct: 806 HGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDG 865
Score = 142 bits (344), Expect = 7e-34
Identities = 74/187 (39%), Positives = 93/187 (49%), Gaps = 7/187 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
N GS+ C C GY P + R DEC + C NT+GS+ C C GY+L
Sbjct: 729 NLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAA 788
Query: 186 GANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRG--DACVDINECHEEGVCPS 356
C D+DEC+ H C C NTEGS++C C+ GY G D C DINEC E+
Sbjct: 789 KDQCEDIDECQH-RHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQ 847
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC--QAPCRNYAGGYRCDCPVG 530
G C+N GS+ C CP G++LD + C D +EC G C Q C N G + C C G
Sbjct: 848 RGDCINTAGSYDCTCPDGFQLD-DNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQG 906
Query: 531 TVRSPSG 551
S G
Sbjct: 907 FSISADG 913
Score = 130 bits (313), Expect = 4e-30
Identities = 72/187 (38%), Positives = 94/187 (50%), Gaps = 8/187 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD 179
+N + C+C GYR R DEC C Q C NT+GS+ C+C G+
Sbjct: 564 INLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMAS 623
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECS-CEDGYE--KRGDACVDINECHEEGVC 350
E+G NC DVDEC R + C NT G++ C C+ GY +RG C DI+EC C
Sbjct: 624 EEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRG-RCEDIDECLNPSTC 682
Query: 351 PSPGRCVNLLGSFRCV-CPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCP 524
P +CVN GS++CV C G+R +C+D DEC + C C N G Y C C
Sbjct: 683 PDE-QCVNSPGSYQCVPCTEGFR--GWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCH 739
Query: 525 VGTVRSP 545
G R+P
Sbjct: 740 KGYTRTP 746
Score = 123 bits (297), Expect = 4e-28
Identities = 62/150 (41%), Positives = 76/150 (50%), Gaps = 6/150 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNT 257
+EC V P C C N Y C+C GY E C D+DEC + H C Q C NT
Sbjct: 549 NECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENT 608
Query: 258 EGSYECSCEDGY--EKRGDACVDINECHEEGVCPSPGRCVNLLGSFRC-VCPRGYRLDAE 428
EGS+ C C G+ + G C+D++EC VC G CVN +G+FRC C GYR+
Sbjct: 609 EGSFLCICPAGFMASEEGTNCIDVDECLRPDVC-GEGHCVNTVGAFRCEYCDSGYRMTQR 667
Query: 429 GARCVDRDECAQTGRC-QAPCRNYAGGYRC 515
G RC D DEC C C N G Y+C
Sbjct: 668 G-RCEDIDECLNPSTCPDEQCVNSPGSYQC 696
Score = 106 bits (254), Expect = 6e-23
Identities = 54/139 (38%), Positives = 75/139 (53%), Gaps = 8/139 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR-PAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELD 179
+NT GS+ C C G++ + + +EC P C C NT+GS+ C+C+ G+ +
Sbjct: 852 INTAGSYDCTCPDGFQLDDNKTCQDINECE-HPGLCGPQGECLNTEGSFHCVCQQGFSIS 910
Query: 180 EDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE--KRGDACVDINECH-EEG 344
DG C D+DEC +T C C NT GS+ C C G++ + G CVD+NEC G
Sbjct: 911 ADGRTCEDIDECVNNT-VCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSG 969
Query: 345 VCPSPGRCVNLLGSFRCVC 401
VC C N+ GSF CVC
Sbjct: 970 VC-GEAFCENVEGSFLCVC 987
Score = 86.2 bits (204), Expect = 7e-17
Identities = 43/115 (37%), Positives = 59/115 (51%), Gaps = 5/115 (4%)
Frame = +3
Query: 201 DVDECERDTHTCQQ-ICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPSPGRCV 371
+++EC + C C N Y C C +GY ++ CVDI+EC + S GRC
Sbjct: 547 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 606
Query: 372 NLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCD-CPVG 530
N GSF C+CP G+ EG C+D DEC + C + C N G +RC+ C G
Sbjct: 607 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSG 661
Score = 84.2 bits (199), Expect = 3e-16
Identities = 43/98 (43%), Positives = 54/98 (55%), Gaps = 5/98 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYEL 176
+NT GSF CVC G+ + GR DEC V CD C NT GS+ CLC G++
Sbjct: 893 LNTEGSFHCVCQQGFSISADGRTCEDIDEC-VNNTVCDSHGFCDNTAGSFRCLCYQGFQA 951
Query: 177 DEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCED 287
+DG C DV+ECE + C + C N EGS+ C C D
Sbjct: 952 PQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCAD 989
Score = 66.1 bits (154), Expect = 8e-11
Identities = 31/80 (38%), Positives = 39/80 (48%), Gaps = 2/80 (2%)
Frame = +3
Query: 318 DINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-C-QAPCR 491
+INEC G C+NL + C+C GYR + +CVD DEC Q C Q C
Sbjct: 547 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 606
Query: 492 NYAGGYRCDCPVGTVRSPSG 551
N G + C CP G + S G
Sbjct: 607 NTEGSFLCICPAGFMASEEG 626
Score = 64.5 bits (150), Expect = 2e-10
Identities = 34/90 (37%), Positives = 44/90 (48%), Gaps = 4/90 (4%)
Frame = +3
Query: 186 GANCRDVDECER-DTHTCQQ-ICSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCP 353
G N +D DEC C+ C NT YEC C+ G Y+ C D++EC + C
Sbjct: 1093 GENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCI 1152
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCV 443
G+CVN GS+ C C LDA RC+
Sbjct: 1153 D-GQCVNTEGSYNCFCTHPMVLDASEKRCI 1181
Score = 58.8 bits (136), Expect = 1e-08
Identities = 60/205 (29%), Positives = 79/205 (38%), Gaps = 27/205 (13%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLC-------- 158
NT GSFRC+C G++ G+G +EC + C + C N +GS+ C+C
Sbjct: 936 NTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYS 995
Query: 159 --------RTGYELDEDGANCRDVD-ECE---RDTHTCQQICSNTEGSYECSCEDGYEKR 302
RT +LD D ++ EC D C + + EC C G
Sbjct: 996 PMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSG-AGW 1054
Query: 303 GDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRL-DAEGARCVDRDECAQTGR-- 473
GD C +I C G C G P G +A G D DEC G+
Sbjct: 1055 GDNC-EIFPCPVLGTAEFTEMCPKGKG----FVPAGESSSEAGGENYKDADECLLFGQEI 1109
Query: 474 CQAP-CRNYAGGYRCDCPVGTVRSP 545
C+ C N GY C C GT P
Sbjct: 1110 CKNGFCLNTRPGYECYCKQGTYYDP 1134
Score = 58.4 bits (135), Expect = 2e-08
Identities = 31/85 (36%), Positives = 45/85 (52%), Gaps = 2/85 (2%)
Frame = +3
Query: 279 CEDGYEKRGDA-CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE 455
C GY++ + C DINEC +GVCP+ G C+N +GS+RC C G+ D + CV
Sbjct: 286 CLPGYKRVNNTFCQDINECQLQGVCPN-GECLNTMGSYRCTCKIGFGPDPTFSSCVPDPP 344
Query: 456 CAQTGRCQAPC-RNYAGGYRCDCPV 527
+ PC R + G +C P+
Sbjct: 345 VISEEK--GPCYRLVSSGRQCMHPL 367
Score = 56.4 bits (130), Expect = 6e-08
Identities = 40/118 (33%), Positives = 49/118 (41%), Gaps = 15/118 (12%)
Frame = +3
Query: 33 CVCGPGYRPAGRG--------VRGRDECAVRPPP-CDQ-LCHNTDGSYDCLCRTGYELDE 182
C G G+ PAG + DEC + C C NT Y+C C+ G D
Sbjct: 1075 CPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDP 1134
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCE-----DGYEKRGDACVDINECHEE 341
C D+DEC+ + C NTEGSY C C D EKR + NE EE
Sbjct: 1135 VKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEE 1192
Score = 54.0 bits (124), Expect = 3e-07
Identities = 39/141 (27%), Positives = 55/141 (39%), Gaps = 4/141 (2%)
Frame = +3
Query: 111 CDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECE-RDTHTCQQICSNTEGSYECSCED 287
CD + +C C +G G NC ++ C T ++C +G E
Sbjct: 1033 CDNVLAPNVTKQECCCTSGAGW---GDNC-EIFPCPVLGTAEFTEMCPKGKGFVPAG-ES 1087
Query: 288 GYEKRGDACVDINECHEEG--VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA 461
E G+ D +EC G +C + G C+N + C C +G D +C D DEC
Sbjct: 1088 SSEAGGENYKDADECLLFGQEICKN-GFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQ 1146
Query: 462 QTGRC-QAPCRNYAGGYRCDC 521
C C N G Y C C
Sbjct: 1147 DPSSCIDGQCVNTEGSYNCFC 1167
Score = 50.8 bits (116), Expect = 3e-06
Identities = 28/87 (32%), Positives = 40/87 (45%), Gaps = 6/87 (6%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTH---TCQQI-CS 251
+EC + + C Y C C GY LD C DV+EC+ + C+ C
Sbjct: 1297 EECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCI 1356
Query: 252 NTEGSYECSCEDGY--EKRGDACVDIN 326
NT+GSY+C C GY + + C +N
Sbjct: 1357 NTDGSYKCLCLPGYVPSDKPNYCTPLN 1383
Score = 49.2 bits (112), Expect = 9e-06
Identities = 23/62 (37%), Positives = 33/62 (53%), Gaps = 6/62 (9%)
Frame = +3
Query: 246 CSNTEGSYECSCEDGY--EKRGDACVDINECHE----EGVCPSPGRCVNLLGSFRCVCPR 407
C + Y C C DGY + CVD+NEC E +C + +C+N GS++C+C
Sbjct: 1310 CVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKN-AKCINTDGSYKCLCLP 1368
Query: 408 GY 413
GY
Sbjct: 1369 GY 1370
Score = 47.6 bits (108), Expect = 3e-05
Identities = 29/77 (37%), Positives = 36/77 (46%), Gaps = 5/77 (6%)
Frame = +3
Query: 327 ECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR----CQ-APCR 491
EC C + GRCV + + C C GY LD CVD +EC + C+ A C
Sbjct: 1298 ECGILNGCEN-GRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCI 1356
Query: 492 NYAGGYRCDCPVGTVRS 542
N G Y+C C G V S
Sbjct: 1357 NTDGSYKCLCLPGYVPS 1373
Score = 38.3 bits (85), Expect = 0.018
Identities = 27/98 (27%), Positives = 42/98 (42%), Gaps = 3/98 (3%)
Frame = +3
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINE 329
C GY+ + C+D++EC+ C NT GSY C+C+ G+ + +CV
Sbjct: 286 CLPGYKR-VNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVP--- 341
Query: 330 CHEEGVCPSPGRCVNLLGSFR-CVCPRGYRLDAEGARC 440
+ G C L+ S R C+ P L + C
Sbjct: 342 -DPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCC 378
Score = 35.5 bits (78), Expect = 0.12
Identities = 18/51 (35%), Positives = 22/51 (43%), Gaps = 1/51 (1%)
Frame = +3
Query: 399 CPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPVGTVRSPS 548
C GY+ C D +EC G C C N G YRC C +G P+
Sbjct: 286 CLPGYKR-VNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPT 335
Score = 33.5 bits (73), Expect = 0.50
Identities = 17/54 (31%), Positives = 27/54 (50%), Gaps = 1/54 (1%)
Frame = +3
Query: 39 CGPGYRPAGRGV-RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
C PGY+ + +EC ++ + C NT GSY C C+ G+ D ++C
Sbjct: 286 CLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
Score = 31.1 bits (67), Expect = 2.7
Identities = 10/20 (50%), Positives = 16/20 (80%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGR 68
+NT GS++C+C PGY P+ +
Sbjct: 1356 INTDGSYKCLCLPGYVPSDK 1375
>AF489528-1|AAM03124.1| 1394|Homo sapiens transforming growth
factor-beta binding protein-1S protein.
Length = 1394
Score = 162 bits (394), Expect = 6e-40
Identities = 77/179 (43%), Positives = 98/179 (54%), Gaps = 6/179 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT GSFRC CG GY+ A DEC R C NT+GS+ C+C GY
Sbjct: 769 NTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGL 828
Query: 186 GANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD-ACVDINECHEEGVCPSP 359
G +C D++EC D CQ+ C NT GSY+C+C DG++ + C DINEC G+C
Sbjct: 829 GDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQ 888
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRCDCPVG 530
G C+N GSF CVC +G+ + A+G C D DEC C + C N AG +RC C G
Sbjct: 889 GECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQG 947
Score = 148 bits (359), Expect = 1e-35
Identities = 79/179 (44%), Positives = 100/179 (55%), Gaps = 9/179 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQL-CHNTDGSYDCLCRTGYELDE 182
NT GSF+CVC GYR +G G D EC C + C NT GSYDC C G++LD
Sbjct: 810 NTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLD- 868
Query: 183 DGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVC 350
D C+D++ECE C Q C NTEGS+ C C+ G+ D C DI+EC VC
Sbjct: 869 DNKTCQDINECEHPG-LCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVC 927
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC-QAPCRNYAGGYRCDC 521
S G C N GSFRC+C +G++ +G CVD +EC +G C +A C N G + C C
Sbjct: 928 DSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVC 986
Score = 144 bits (349), Expect = 2e-34
Identities = 75/180 (41%), Positives = 97/180 (53%), Gaps = 6/180 (3%)
Frame = +3
Query: 9 VNTIGSFRCV-CGPGYRPAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDE 182
VN+ GS++CV C G+R DEC + P C + C N +GSY C C GY
Sbjct: 687 VNSPGSYQCVPCTEGFRGWNGQCLDVDEC-LEPNVCANGDCSNLEGSYMCSCHKGYTRTP 745
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRG--DACVDINECHEEGVCPS 356
D +CRD+DEC++ C NTEGS+ C+C GY+ D C DI+EC +C +
Sbjct: 746 DHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLC-A 804
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGRCQ-APCRNYAGGYRCDCPVG 530
G+C N GSF+CVC +GYR G C D +EC + CQ C N AG Y C CP G
Sbjct: 805 HGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDG 864
Score = 142 bits (344), Expect = 7e-34
Identities = 74/187 (39%), Positives = 93/187 (49%), Gaps = 7/187 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
N GS+ C C GY P + R DEC + C NT+GS+ C C GY+L
Sbjct: 728 NLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAA 787
Query: 186 GANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRG--DACVDINECHEEGVCPS 356
C D+DEC+ H C C NTEGS++C C+ GY G D C DINEC E+
Sbjct: 788 KDQCEDIDECQH-RHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQ 846
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC--QAPCRNYAGGYRCDCPVG 530
G C+N GS+ C CP G++LD + C D +EC G C Q C N G + C C G
Sbjct: 847 RGDCINTAGSYDCTCPDGFQLD-DNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQG 905
Query: 531 TVRSPSG 551
S G
Sbjct: 906 FSISADG 912
Score = 130 bits (313), Expect = 4e-30
Identities = 72/187 (38%), Positives = 94/187 (50%), Gaps = 8/187 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD 179
+N + C+C GYR R DEC C Q C NT+GS+ C+C G+
Sbjct: 563 INLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMAS 622
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECS-CEDGYE--KRGDACVDINECHEEGVC 350
E+G NC DVDEC R + C NT G++ C C+ GY +RG C DI+EC C
Sbjct: 623 EEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRG-RCEDIDECLNPSTC 681
Query: 351 PSPGRCVNLLGSFRCV-CPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCP 524
P +CVN GS++CV C G+R +C+D DEC + C C N G Y C C
Sbjct: 682 PDE-QCVNSPGSYQCVPCTEGFR--GWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCH 738
Query: 525 VGTVRSP 545
G R+P
Sbjct: 739 KGYTRTP 745
Score = 123 bits (297), Expect = 4e-28
Identities = 62/150 (41%), Positives = 76/150 (50%), Gaps = 6/150 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNT 257
+EC V P C C N Y C+C GY E C D+DEC + H C Q C NT
Sbjct: 548 NECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENT 607
Query: 258 EGSYECSCEDGY--EKRGDACVDINECHEEGVCPSPGRCVNLLGSFRC-VCPRGYRLDAE 428
EGS+ C C G+ + G C+D++EC VC G CVN +G+FRC C GYR+
Sbjct: 608 EGSFLCICPAGFMASEEGTNCIDVDECLRPDVC-GEGHCVNTVGAFRCEYCDSGYRMTQR 666
Query: 429 GARCVDRDECAQTGRC-QAPCRNYAGGYRC 515
G RC D DEC C C N G Y+C
Sbjct: 667 G-RCEDIDECLNPSTCPDEQCVNSPGSYQC 695
Score = 106 bits (254), Expect = 6e-23
Identities = 54/139 (38%), Positives = 75/139 (53%), Gaps = 8/139 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR-PAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELD 179
+NT GS+ C C G++ + + +EC P C C NT+GS+ C+C+ G+ +
Sbjct: 851 INTAGSYDCTCPDGFQLDDNKTCQDINECE-HPGLCGPQGECLNTEGSFHCVCQQGFSIS 909
Query: 180 EDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE--KRGDACVDINECH-EEG 344
DG C D+DEC +T C C NT GS+ C C G++ + G CVD+NEC G
Sbjct: 910 ADGRTCEDIDECVNNT-VCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSG 968
Query: 345 VCPSPGRCVNLLGSFRCVC 401
VC C N+ GSF CVC
Sbjct: 969 VC-GEAFCENVEGSFLCVC 986
Score = 86.2 bits (204), Expect = 7e-17
Identities = 43/115 (37%), Positives = 59/115 (51%), Gaps = 5/115 (4%)
Frame = +3
Query: 201 DVDECERDTHTCQQ-ICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPSPGRCV 371
+++EC + C C N Y C C +GY ++ CVDI+EC + S GRC
Sbjct: 546 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 605
Query: 372 NLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCD-CPVG 530
N GSF C+CP G+ EG C+D DEC + C + C N G +RC+ C G
Sbjct: 606 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSG 660
Score = 84.2 bits (199), Expect = 3e-16
Identities = 43/98 (43%), Positives = 54/98 (55%), Gaps = 5/98 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYEL 176
+NT GSF CVC G+ + GR DEC V CD C NT GS+ CLC G++
Sbjct: 892 LNTEGSFHCVCQQGFSISADGRTCEDIDEC-VNNTVCDSHGFCDNTAGSFRCLCYQGFQA 950
Query: 177 DEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCED 287
+DG C DV+ECE + C + C N EGS+ C C D
Sbjct: 951 PQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCAD 988
Score = 66.1 bits (154), Expect = 8e-11
Identities = 31/80 (38%), Positives = 39/80 (48%), Gaps = 2/80 (2%)
Frame = +3
Query: 318 DINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-C-QAPCR 491
+INEC G C+NL + C+C GYR + +CVD DEC Q C Q C
Sbjct: 546 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 605
Query: 492 NYAGGYRCDCPVGTVRSPSG 551
N G + C CP G + S G
Sbjct: 606 NTEGSFLCICPAGFMASEEG 625
Score = 64.5 bits (150), Expect = 2e-10
Identities = 34/90 (37%), Positives = 44/90 (48%), Gaps = 4/90 (4%)
Frame = +3
Query: 186 GANCRDVDECER-DTHTCQQ-ICSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCP 353
G N +D DEC C+ C NT YEC C+ G Y+ C D++EC + C
Sbjct: 1092 GENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCI 1151
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCV 443
G+CVN GS+ C C LDA RC+
Sbjct: 1152 D-GQCVNTEGSYNCFCTHPMVLDASEKRCI 1180
Score = 58.8 bits (136), Expect = 1e-08
Identities = 60/205 (29%), Positives = 79/205 (38%), Gaps = 27/205 (13%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLC-------- 158
NT GSFRC+C G++ G+G +EC + C + C N +GS+ C+C
Sbjct: 935 NTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYS 994
Query: 159 --------RTGYELDEDGANCRDVD-ECE---RDTHTCQQICSNTEGSYECSCEDGYEKR 302
RT +LD D ++ EC D C + + EC C G
Sbjct: 995 PMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSG-AGW 1053
Query: 303 GDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRL-DAEGARCVDRDECAQTGR-- 473
GD C +I C G C G P G +A G D DEC G+
Sbjct: 1054 GDNC-EIFPCPVLGTAEFTEMCPKGKG----FVPAGESSSEAGGENYKDADECLLFGQEI 1108
Query: 474 CQAP-CRNYAGGYRCDCPVGTVRSP 545
C+ C N GY C C GT P
Sbjct: 1109 CKNGFCLNTRPGYECYCKQGTYYDP 1133
Score = 58.4 bits (135), Expect = 2e-08
Identities = 31/85 (36%), Positives = 45/85 (52%), Gaps = 2/85 (2%)
Frame = +3
Query: 279 CEDGYEKRGDA-CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE 455
C GY++ + C DINEC +GVCP+ G C+N +GS+RC C G+ D + CV
Sbjct: 286 CLPGYKRVNNTFCQDINECQLQGVCPN-GECLNTMGSYRCTCKIGFGPDPTFSSCVPDPP 344
Query: 456 CAQTGRCQAPC-RNYAGGYRCDCPV 527
+ PC R + G +C P+
Sbjct: 345 VISEEK--GPCYRLVSSGRQCMHPL 367
Score = 56.4 bits (130), Expect = 6e-08
Identities = 40/118 (33%), Positives = 49/118 (41%), Gaps = 15/118 (12%)
Frame = +3
Query: 33 CVCGPGYRPAGRG--------VRGRDECAVRPPP-CDQ-LCHNTDGSYDCLCRTGYELDE 182
C G G+ PAG + DEC + C C NT Y+C C+ G D
Sbjct: 1074 CPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDP 1133
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCE-----DGYEKRGDACVDINECHEE 341
C D+DEC+ + C NTEGSY C C D EKR + NE EE
Sbjct: 1134 VKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEE 1191
Score = 54.0 bits (124), Expect = 3e-07
Identities = 39/141 (27%), Positives = 55/141 (39%), Gaps = 4/141 (2%)
Frame = +3
Query: 111 CDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECE-RDTHTCQQICSNTEGSYECSCED 287
CD + +C C +G G NC ++ C T ++C +G E
Sbjct: 1032 CDNVLAPNVTKQECCCTSGAGW---GDNC-EIFPCPVLGTAEFTEMCPKGKGFVPAG-ES 1086
Query: 288 GYEKRGDACVDINECHEEG--VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA 461
E G+ D +EC G +C + G C+N + C C +G D +C D DEC
Sbjct: 1087 SSEAGGENYKDADECLLFGQEICKN-GFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQ 1145
Query: 462 QTGRC-QAPCRNYAGGYRCDC 521
C C N G Y C C
Sbjct: 1146 DPSSCIDGQCVNTEGSYNCFC 1166
Score = 51.2 bits (117), Expect = 2e-06
Identities = 28/87 (32%), Positives = 40/87 (45%), Gaps = 6/87 (6%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTH---TCQQI-CS 251
+EC + + C Y C C GY LD C DV+EC+ + C+ C
Sbjct: 1296 EECGILNGCENGRCVRVQEGYTCDCLDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCI 1355
Query: 252 NTEGSYECSCEDGY--EKRGDACVDIN 326
NT+GSY+C C GY + + C +N
Sbjct: 1356 NTDGSYKCLCLPGYVPSDKPNYCTPLN 1382
Score = 49.2 bits (112), Expect = 9e-06
Identities = 23/62 (37%), Positives = 33/62 (53%), Gaps = 6/62 (9%)
Frame = +3
Query: 246 CSNTEGSYECSCEDGY--EKRGDACVDINECHE----EGVCPSPGRCVNLLGSFRCVCPR 407
C + Y C C DGY + CVD+NEC E +C + +C+N GS++C+C
Sbjct: 1309 CVRVQEGYTCDCLDGYHLDTAKMTCVDVNECDELNNRMSLCKN-AKCINTDGSYKCLCLP 1367
Query: 408 GY 413
GY
Sbjct: 1368 GY 1369
Score = 48.0 bits (109), Expect = 2e-05
Identities = 29/77 (37%), Positives = 36/77 (46%), Gaps = 5/77 (6%)
Frame = +3
Query: 327 ECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR----CQ-APCR 491
EC C + GRCV + + C C GY LD CVD +EC + C+ A C
Sbjct: 1297 ECGILNGCEN-GRCVRVQEGYTCDCLDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCI 1355
Query: 492 NYAGGYRCDCPVGTVRS 542
N G Y+C C G V S
Sbjct: 1356 NTDGSYKCLCLPGYVPS 1372
Score = 35.5 bits (78), Expect = 0.12
Identities = 18/51 (35%), Positives = 22/51 (43%), Gaps = 1/51 (1%)
Frame = +3
Query: 399 CPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPVGTVRSPS 548
C GY+ C D +EC G C C N G YRC C +G P+
Sbjct: 286 CLPGYKR-VNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPT 335
Score = 33.9 bits (74), Expect = 0.38
Identities = 33/135 (24%), Positives = 54/135 (40%), Gaps = 4/135 (2%)
Frame = +3
Query: 39 CGPGYRPAGRGV-RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-RDVDE 212
C PGY+ + +EC ++ + C NT GSY C C+ G+ D ++C D
Sbjct: 286 CLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPV 345
Query: 213 CERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINEC--HEEGVCPSPGRCVNLLGS 386
+ C ++ S+ G + + C + + H E CP PG +
Sbjct: 346 ISEEKGPCYRLVSS--GRQCMHPLSVHLTKQLCCCSVGKAGPHCE-KCPLPG-----TAA 397
Query: 387 FRCVCPRGYRLDAEG 431
F+ +CP G G
Sbjct: 398 FKEICPGGMGYTVSG 412
Score = 31.1 bits (67), Expect = 2.7
Identities = 10/20 (50%), Positives = 16/20 (80%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGR 68
+NT GS++C+C PGY P+ +
Sbjct: 1355 INTDGSYKCLCLPGYVPSDK 1374
>AC019127-1|AAY24260.1| 697|Homo sapiens unknown protein.
Length = 697
Score = 162 bits (394), Expect = 6e-40
Identities = 77/179 (43%), Positives = 98/179 (54%), Gaps = 6/179 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT GSFRC CG GY+ A DEC R C NT+GS+ C+C GY
Sbjct: 223 NTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGL 282
Query: 186 GANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD-ACVDINECHEEGVCPSP 359
G +C D++EC D CQ+ C NT GSY+C+C DG++ + C DINEC G+C
Sbjct: 283 GDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQ 342
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRCDCPVG 530
G C+N GSF CVC +G+ + A+G C D DEC C + C N AG +RC C G
Sbjct: 343 GECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQG 401
Score = 148 bits (359), Expect = 1e-35
Identities = 79/179 (44%), Positives = 100/179 (55%), Gaps = 9/179 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQL-CHNTDGSYDCLCRTGYELDE 182
NT GSF+CVC GYR +G G D EC C + C NT GSYDC C G++LD
Sbjct: 264 NTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLD- 322
Query: 183 DGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVC 350
D C+D++ECE C Q C NTEGS+ C C+ G+ D C DI+EC VC
Sbjct: 323 DNKTCQDINECEHPG-LCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVC 381
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC-QAPCRNYAGGYRCDC 521
S G C N GSFRC+C +G++ +G CVD +EC +G C +A C N G + C C
Sbjct: 382 DSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVC 440
Score = 144 bits (349), Expect = 2e-34
Identities = 75/180 (41%), Positives = 97/180 (53%), Gaps = 6/180 (3%)
Frame = +3
Query: 9 VNTIGSFRCV-CGPGYRPAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDE 182
VN+ GS++CV C G+R DEC + P C + C N +GSY C C GY
Sbjct: 141 VNSPGSYQCVPCTEGFRGWNGQCLDVDEC-LEPNVCANGDCSNLEGSYMCSCHKGYTRTP 199
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRG--DACVDINECHEEGVCPS 356
D +CRD+DEC++ C NTEGS+ C+C GY+ D C DI+EC +C +
Sbjct: 200 DHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLC-A 258
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGRCQ-APCRNYAGGYRCDCPVG 530
G+C N GSF+CVC +GYR G C D +EC + CQ C N AG Y C CP G
Sbjct: 259 HGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDG 318
Score = 142 bits (344), Expect = 7e-34
Identities = 74/187 (39%), Positives = 93/187 (49%), Gaps = 7/187 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
N GS+ C C GY P + R DEC + C NT+GS+ C C GY+L
Sbjct: 182 NLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAA 241
Query: 186 GANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRG--DACVDINECHEEGVCPS 356
C D+DEC+ H C C NTEGS++C C+ GY G D C DINEC E+
Sbjct: 242 KDQCEDIDECQH-RHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQ 300
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC--QAPCRNYAGGYRCDCPVG 530
G C+N GS+ C CP G++LD + C D +EC G C Q C N G + C C G
Sbjct: 301 RGDCINTAGSYDCTCPDGFQLD-DNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQG 359
Query: 531 TVRSPSG 551
S G
Sbjct: 360 FSISADG 366
Score = 130 bits (313), Expect = 4e-30
Identities = 72/187 (38%), Positives = 94/187 (50%), Gaps = 8/187 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD 179
+N + C+C GYR R DEC C Q C NT+GS+ C+C G+
Sbjct: 17 INLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMAS 76
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECS-CEDGYE--KRGDACVDINECHEEGVC 350
E+G NC DVDEC R + C NT G++ C C+ GY +RG C DI+EC C
Sbjct: 77 EEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRG-RCEDIDECLNPSTC 135
Query: 351 PSPGRCVNLLGSFRCV-CPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCP 524
P +CVN GS++CV C G+R +C+D DEC + C C N G Y C C
Sbjct: 136 PDE-QCVNSPGSYQCVPCTEGFR--GWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCH 192
Query: 525 VGTVRSP 545
G R+P
Sbjct: 193 KGYTRTP 199
Score = 123 bits (297), Expect = 4e-28
Identities = 62/150 (41%), Positives = 76/150 (50%), Gaps = 6/150 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNT 257
+EC V P C C N Y C+C GY E C D+DEC + H C Q C NT
Sbjct: 2 NECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENT 61
Query: 258 EGSYECSCEDGY--EKRGDACVDINECHEEGVCPSPGRCVNLLGSFRC-VCPRGYRLDAE 428
EGS+ C C G+ + G C+D++EC VC G CVN +G+FRC C GYR+
Sbjct: 62 EGSFLCICPAGFMASEEGTNCIDVDECLRPDVC-GEGHCVNTVGAFRCEYCDSGYRMTQR 120
Query: 429 GARCVDRDECAQTGRC-QAPCRNYAGGYRC 515
G RC D DEC C C N G Y+C
Sbjct: 121 G-RCEDIDECLNPSTCPDEQCVNSPGSYQC 149
Score = 106 bits (254), Expect = 6e-23
Identities = 54/139 (38%), Positives = 75/139 (53%), Gaps = 8/139 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR-PAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELD 179
+NT GS+ C C G++ + + +EC P C C NT+GS+ C+C+ G+ +
Sbjct: 305 INTAGSYDCTCPDGFQLDDNKTCQDINECE-HPGLCGPQGECLNTEGSFHCVCQQGFSIS 363
Query: 180 EDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE--KRGDACVDINECH-EEG 344
DG C D+DEC +T C C NT GS+ C C G++ + G CVD+NEC G
Sbjct: 364 ADGRTCEDIDECVNNT-VCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSG 422
Query: 345 VCPSPGRCVNLLGSFRCVC 401
VC C N+ GSF CVC
Sbjct: 423 VC-GEAFCENVEGSFLCVC 440
Score = 85.4 bits (202), Expect = 1e-16
Identities = 43/114 (37%), Positives = 58/114 (50%), Gaps = 5/114 (4%)
Frame = +3
Query: 204 VDECERDTHTCQQ-ICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPSPGRCVN 374
++EC + C C N Y C C +GY ++ CVDI+EC + S GRC N
Sbjct: 1 INECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCEN 60
Query: 375 LLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCD-CPVG 530
GSF C+CP G+ EG C+D DEC + C + C N G +RC+ C G
Sbjct: 61 TEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSG 114
Score = 84.2 bits (199), Expect = 3e-16
Identities = 43/98 (43%), Positives = 54/98 (55%), Gaps = 5/98 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYEL 176
+NT GSF CVC G+ + GR DEC V CD C NT GS+ CLC G++
Sbjct: 346 LNTEGSFHCVCQQGFSISADGRTCEDIDEC-VNNTVCDSHGFCDNTAGSFRCLCYQGFQA 404
Query: 177 DEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCED 287
+DG C DV+ECE + C + C N EGS+ C C D
Sbjct: 405 PQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCAD 442
Score = 65.3 bits (152), Expect = 1e-10
Identities = 31/79 (39%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +3
Query: 321 INECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-C-QAPCRN 494
INEC G C+NL + C+C GYR + +CVD DEC Q C Q C N
Sbjct: 1 INECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCEN 60
Query: 495 YAGGYRCDCPVGTVRSPSG 551
G + C CP G + S G
Sbjct: 61 TEGSFLCICPAGFMASEEG 79
Score = 64.5 bits (150), Expect = 2e-10
Identities = 34/90 (37%), Positives = 44/90 (48%), Gaps = 4/90 (4%)
Frame = +3
Query: 186 GANCRDVDECER-DTHTCQQ-ICSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCP 353
G N +D DEC C+ C NT YEC C+ G Y+ C D++EC + C
Sbjct: 546 GENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCI 605
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCV 443
G+CVN GS+ C C LDA RC+
Sbjct: 606 D-GQCVNTEGSYNCFCTHPMVLDASEKRCI 634
Score = 58.8 bits (136), Expect = 1e-08
Identities = 60/205 (29%), Positives = 79/205 (38%), Gaps = 27/205 (13%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLC-------- 158
NT GSFRC+C G++ G+G +EC + C + C N +GS+ C+C
Sbjct: 389 NTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYS 448
Query: 159 --------RTGYELDEDGANCRDVD-ECE---RDTHTCQQICSNTEGSYECSCEDGYEKR 302
RT +LD D ++ EC D C + + EC C G
Sbjct: 449 PMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGVGW- 507
Query: 303 GDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRL-DAEGARCVDRDECAQTGR-- 473
GD C +I C G C G P G +A G D DEC G+
Sbjct: 508 GDNC-EIFPCPVLGTAEFTEMCPKGKG----FVPAGESSSEAGGENYKDADECLLFGQEI 562
Query: 474 CQAP-CRNYAGGYRCDCPVGTVRSP 545
C+ C N GY C C GT P
Sbjct: 563 CKNGFCLNTRPGYECYCKQGTYYDP 587
Score = 56.4 bits (130), Expect = 6e-08
Identities = 40/118 (33%), Positives = 49/118 (41%), Gaps = 15/118 (12%)
Frame = +3
Query: 33 CVCGPGYRPAGRG--------VRGRDECAVRPPP-CDQ-LCHNTDGSYDCLCRTGYELDE 182
C G G+ PAG + DEC + C C NT Y+C C+ G D
Sbjct: 528 CPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDP 587
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCE-----DGYEKRGDACVDINECHEE 341
C D+DEC+ + C NTEGSY C C D EKR + NE EE
Sbjct: 588 VKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEE 645
Score = 54.4 bits (125), Expect = 3e-07
Identities = 39/141 (27%), Positives = 55/141 (39%), Gaps = 4/141 (2%)
Frame = +3
Query: 111 CDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECE-RDTHTCQQICSNTEGSYECSCED 287
CD + +C C +G G NC ++ C T ++C +G E
Sbjct: 486 CDNVLAPNVTKQECCCTSGVGW---GDNC-EIFPCPVLGTAEFTEMCPKGKGFVPAG-ES 540
Query: 288 GYEKRGDACVDINECHEEG--VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA 461
E G+ D +EC G +C + G C+N + C C +G D +C D DEC
Sbjct: 541 SSEAGGENYKDADECLLFGQEICKN-GFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQ 599
Query: 462 QTGRC-QAPCRNYAGGYRCDC 521
C C N G Y C C
Sbjct: 600 DPSSCIDGQCVNTEGSYNCFC 620
>AB208801-1|BAD92038.1| 1348|Homo sapiens latent transforming growth
factor beta binding protein 1 isoform LTBP-1S varian
protein.
Length = 1348
Score = 162 bits (394), Expect = 6e-40
Identities = 77/179 (43%), Positives = 98/179 (54%), Gaps = 6/179 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT GSFRC CG GY+ A DEC R C NT+GS+ C+C GY
Sbjct: 723 NTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGL 782
Query: 186 GANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD-ACVDINECHEEGVCPSP 359
G +C D++EC D CQ+ C NT GSY+C+C DG++ + C DINEC G+C
Sbjct: 783 GDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQ 842
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRCDCPVG 530
G C+N GSF CVC +G+ + A+G C D DEC C + C N AG +RC C G
Sbjct: 843 GECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQG 901
Score = 148 bits (359), Expect = 1e-35
Identities = 79/179 (44%), Positives = 100/179 (55%), Gaps = 9/179 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQL-CHNTDGSYDCLCRTGYELDE 182
NT GSF+CVC GYR +G G D EC C + C NT GSYDC C G++LD
Sbjct: 764 NTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLD- 822
Query: 183 DGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVC 350
D C+D++ECE C Q C NTEGS+ C C+ G+ D C DI+EC VC
Sbjct: 823 DNKTCQDINECEHPG-LCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVC 881
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC-QAPCRNYAGGYRCDC 521
S G C N GSFRC+C +G++ +G CVD +EC +G C +A C N G + C C
Sbjct: 882 DSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVC 940
Score = 144 bits (349), Expect = 2e-34
Identities = 75/180 (41%), Positives = 97/180 (53%), Gaps = 6/180 (3%)
Frame = +3
Query: 9 VNTIGSFRCV-CGPGYRPAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDE 182
VN+ GS++CV C G+R DEC + P C + C N +GSY C C GY
Sbjct: 641 VNSPGSYQCVPCTEGFRGWNGQCLDVDEC-LEPNVCANGDCSNLEGSYMCSCHKGYTRTP 699
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRG--DACVDINECHEEGVCPS 356
D +CRD+DEC++ C NTEGS+ C+C GY+ D C DI+EC +C +
Sbjct: 700 DHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLC-A 758
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGRCQ-APCRNYAGGYRCDCPVG 530
G+C N GSF+CVC +GYR G C D +EC + CQ C N AG Y C CP G
Sbjct: 759 HGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDG 818
Score = 142 bits (344), Expect = 7e-34
Identities = 74/187 (39%), Positives = 93/187 (49%), Gaps = 7/187 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
N GS+ C C GY P + R DEC + C NT+GS+ C C GY+L
Sbjct: 682 NLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAA 741
Query: 186 GANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRG--DACVDINECHEEGVCPS 356
C D+DEC+ H C C NTEGS++C C+ GY G D C DINEC E+
Sbjct: 742 KDQCEDIDECQH-RHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQ 800
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC--QAPCRNYAGGYRCDCPVG 530
G C+N GS+ C CP G++LD + C D +EC G C Q C N G + C C G
Sbjct: 801 RGDCINTAGSYDCTCPDGFQLD-DNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQG 859
Query: 531 TVRSPSG 551
S G
Sbjct: 860 FSISADG 866
Score = 130 bits (313), Expect = 4e-30
Identities = 72/187 (38%), Positives = 94/187 (50%), Gaps = 8/187 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD 179
+N + C+C GYR R DEC C Q C NT+GS+ C+C G+
Sbjct: 517 INLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMAS 576
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECS-CEDGYE--KRGDACVDINECHEEGVC 350
E+G NC DVDEC R + C NT G++ C C+ GY +RG C DI+EC C
Sbjct: 577 EEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRG-RCEDIDECLNPSTC 635
Query: 351 PSPGRCVNLLGSFRCV-CPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCP 524
P +CVN GS++CV C G+R +C+D DEC + C C N G Y C C
Sbjct: 636 PDE-QCVNSPGSYQCVPCTEGFR--GWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCH 692
Query: 525 VGTVRSP 545
G R+P
Sbjct: 693 KGYTRTP 699
Score = 123 bits (297), Expect = 4e-28
Identities = 62/150 (41%), Positives = 76/150 (50%), Gaps = 6/150 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNT 257
+EC V P C C N Y C+C GY E C D+DEC + H C Q C NT
Sbjct: 502 NECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENT 561
Query: 258 EGSYECSCEDGY--EKRGDACVDINECHEEGVCPSPGRCVNLLGSFRC-VCPRGYRLDAE 428
EGS+ C C G+ + G C+D++EC VC G CVN +G+FRC C GYR+
Sbjct: 562 EGSFLCICPAGFMASEEGTNCIDVDECLRPDVC-GEGHCVNTVGAFRCEYCDSGYRMTQR 620
Query: 429 GARCVDRDECAQTGRC-QAPCRNYAGGYRC 515
G RC D DEC C C N G Y+C
Sbjct: 621 G-RCEDIDECLNPSTCPDEQCVNSPGSYQC 649
Score = 106 bits (254), Expect = 6e-23
Identities = 54/139 (38%), Positives = 75/139 (53%), Gaps = 8/139 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR-PAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELD 179
+NT GS+ C C G++ + + +EC P C C NT+GS+ C+C+ G+ +
Sbjct: 805 INTAGSYDCTCPDGFQLDDNKTCQDINECE-HPGLCGPQGECLNTEGSFHCVCQQGFSIS 863
Query: 180 EDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE--KRGDACVDINECH-EEG 344
DG C D+DEC +T C C NT GS+ C C G++ + G CVD+NEC G
Sbjct: 864 ADGRTCEDIDECVNNT-VCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSG 922
Query: 345 VCPSPGRCVNLLGSFRCVC 401
VC C N+ GSF CVC
Sbjct: 923 VC-GEAFCENVEGSFLCVC 940
Score = 86.2 bits (204), Expect = 7e-17
Identities = 43/115 (37%), Positives = 59/115 (51%), Gaps = 5/115 (4%)
Frame = +3
Query: 201 DVDECERDTHTCQQ-ICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPSPGRCV 371
+++EC + C C N Y C C +GY ++ CVDI+EC + S GRC
Sbjct: 500 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 559
Query: 372 NLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCD-CPVG 530
N GSF C+CP G+ EG C+D DEC + C + C N G +RC+ C G
Sbjct: 560 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSG 614
Score = 84.2 bits (199), Expect = 3e-16
Identities = 43/98 (43%), Positives = 54/98 (55%), Gaps = 5/98 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYEL 176
+NT GSF CVC G+ + GR DEC V CD C NT GS+ CLC G++
Sbjct: 846 LNTEGSFHCVCQQGFSISADGRTCEDIDEC-VNNTVCDSHGFCDNTAGSFRCLCYQGFQA 904
Query: 177 DEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCED 287
+DG C DV+ECE + C + C N EGS+ C C D
Sbjct: 905 PQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCAD 942
Score = 66.1 bits (154), Expect = 8e-11
Identities = 31/80 (38%), Positives = 39/80 (48%), Gaps = 2/80 (2%)
Frame = +3
Query: 318 DINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-C-QAPCR 491
+INEC G C+NL + C+C GYR + +CVD DEC Q C Q C
Sbjct: 500 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 559
Query: 492 NYAGGYRCDCPVGTVRSPSG 551
N G + C CP G + S G
Sbjct: 560 NTEGSFLCICPAGFMASEEG 579
Score = 64.5 bits (150), Expect = 2e-10
Identities = 34/90 (37%), Positives = 44/90 (48%), Gaps = 4/90 (4%)
Frame = +3
Query: 186 GANCRDVDECER-DTHTCQQ-ICSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCP 353
G N +D DEC C+ C NT YEC C+ G Y+ C D++EC + C
Sbjct: 1046 GENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCI 1105
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCV 443
G+CVN GS+ C C LDA RC+
Sbjct: 1106 D-GQCVNTEGSYNCFCTHPMVLDASEKRCI 1134
Score = 58.8 bits (136), Expect = 1e-08
Identities = 60/205 (29%), Positives = 79/205 (38%), Gaps = 27/205 (13%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLC-------- 158
NT GSFRC+C G++ G+G +EC + C + C N +GS+ C+C
Sbjct: 889 NTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYS 948
Query: 159 --------RTGYELDEDGANCRDVD-ECE---RDTHTCQQICSNTEGSYECSCEDGYEKR 302
RT +LD D ++ EC D C + + EC C G
Sbjct: 949 PMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSG-AGW 1007
Query: 303 GDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRL-DAEGARCVDRDECAQTGR-- 473
GD C +I C G C G P G +A G D DEC G+
Sbjct: 1008 GDNC-EIFPCPVLGTAEFTEMCPKGKG----FVPAGESSSEAGGENYKDADECLLFGQEI 1062
Query: 474 CQAP-CRNYAGGYRCDCPVGTVRSP 545
C+ C N GY C C GT P
Sbjct: 1063 CKNGFCLNTRPGYECYCKQGTYYDP 1087
Score = 58.4 bits (135), Expect = 2e-08
Identities = 31/85 (36%), Positives = 45/85 (52%), Gaps = 2/85 (2%)
Frame = +3
Query: 279 CEDGYEKRGDA-CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE 455
C GY++ + C DINEC +GVCP+ G C+N +GS+RC C G+ D + CV
Sbjct: 292 CLPGYKRVNNTFCQDINECQLQGVCPN-GECLNTMGSYRCTCKIGFGPDPTFSSCVPDPP 350
Query: 456 CAQTGRCQAPC-RNYAGGYRCDCPV 527
+ PC R + G +C P+
Sbjct: 351 VISEEK--GPCYRLVSSGRQCMHPL 373
Score = 56.4 bits (130), Expect = 6e-08
Identities = 40/118 (33%), Positives = 49/118 (41%), Gaps = 15/118 (12%)
Frame = +3
Query: 33 CVCGPGYRPAGRG--------VRGRDECAVRPPP-CDQ-LCHNTDGSYDCLCRTGYELDE 182
C G G+ PAG + DEC + C C NT Y+C C+ G D
Sbjct: 1028 CPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDP 1087
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCE-----DGYEKRGDACVDINECHEE 341
C D+DEC+ + C NTEGSY C C D EKR + NE EE
Sbjct: 1088 VKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEE 1145
Score = 54.0 bits (124), Expect = 3e-07
Identities = 39/141 (27%), Positives = 55/141 (39%), Gaps = 4/141 (2%)
Frame = +3
Query: 111 CDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECE-RDTHTCQQICSNTEGSYECSCED 287
CD + +C C +G G NC ++ C T ++C +G E
Sbjct: 986 CDNVLAPNVTKQECCCTSGAGW---GDNC-EIFPCPVLGTAEFTEMCPKGKGFVPAG-ES 1040
Query: 288 GYEKRGDACVDINECHEEG--VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA 461
E G+ D +EC G +C + G C+N + C C +G D +C D DEC
Sbjct: 1041 SSEAGGENYKDADECLLFGQEICKN-GFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQ 1099
Query: 462 QTGRC-QAPCRNYAGGYRCDC 521
C C N G Y C C
Sbjct: 1100 DPSSCIDGQCVNTEGSYNCFC 1120
Score = 50.8 bits (116), Expect = 3e-06
Identities = 28/87 (32%), Positives = 40/87 (45%), Gaps = 6/87 (6%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTH---TCQQI-CS 251
+EC + + C Y C C GY LD C DV+EC+ + C+ C
Sbjct: 1250 EECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCI 1309
Query: 252 NTEGSYECSCEDGY--EKRGDACVDIN 326
NT+GSY+C C GY + + C +N
Sbjct: 1310 NTDGSYKCLCLPGYVPSDKPNYCTPLN 1336
Score = 49.2 bits (112), Expect = 9e-06
Identities = 23/62 (37%), Positives = 33/62 (53%), Gaps = 6/62 (9%)
Frame = +3
Query: 246 CSNTEGSYECSCEDGY--EKRGDACVDINECHE----EGVCPSPGRCVNLLGSFRCVCPR 407
C + Y C C DGY + CVD+NEC E +C + +C+N GS++C+C
Sbjct: 1263 CVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKN-AKCINTDGSYKCLCLP 1321
Query: 408 GY 413
GY
Sbjct: 1322 GY 1323
Score = 47.6 bits (108), Expect = 3e-05
Identities = 29/77 (37%), Positives = 36/77 (46%), Gaps = 5/77 (6%)
Frame = +3
Query: 327 ECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR----CQ-APCR 491
EC C + GRCV + + C C GY LD CVD +EC + C+ A C
Sbjct: 1251 ECGILNGCEN-GRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCI 1309
Query: 492 NYAGGYRCDCPVGTVRS 542
N G Y+C C G V S
Sbjct: 1310 NTDGSYKCLCLPGYVPS 1326
Score = 38.3 bits (85), Expect = 0.018
Identities = 27/98 (27%), Positives = 42/98 (42%), Gaps = 3/98 (3%)
Frame = +3
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINE 329
C GY+ + C+D++EC+ C NT GSY C+C+ G+ + +CV
Sbjct: 292 CLPGYKR-VNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVP--- 347
Query: 330 CHEEGVCPSPGRCVNLLGSFR-CVCPRGYRLDAEGARC 440
+ G C L+ S R C+ P L + C
Sbjct: 348 -DPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCC 384
Score = 35.5 bits (78), Expect = 0.12
Identities = 18/51 (35%), Positives = 22/51 (43%), Gaps = 1/51 (1%)
Frame = +3
Query: 399 CPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPVGTVRSPS 548
C GY+ C D +EC G C C N G YRC C +G P+
Sbjct: 292 CLPGYKR-VNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPT 341
Score = 33.5 bits (73), Expect = 0.50
Identities = 17/54 (31%), Positives = 27/54 (50%), Gaps = 1/54 (1%)
Frame = +3
Query: 39 CGPGYRPAGRGV-RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
C PGY+ + +EC ++ + C NT GSY C C+ G+ D ++C
Sbjct: 292 CLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 345
Score = 31.1 bits (67), Expect = 2.7
Identities = 10/20 (50%), Positives = 16/20 (80%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGR 68
+NT GS++C+C PGY P+ +
Sbjct: 1309 INTDGSYKCLCLPGYVPSDK 1328
>X62008-1|CAB56534.1| 517|Homo sapiens fibrillin 15 protein.
Length = 517
Score = 157 bits (380), Expect = 3e-38
Identities = 79/187 (42%), Positives = 101/187 (54%), Gaps = 9/187 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD- 179
NTIGSF+C C G+ R DEC + P C + C NT G ++C C GYE
Sbjct: 250 NTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGF 309
Query: 180 EDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEG-V 347
NC D+DEC+RD C+ +C NTEGSY C C G++ + AC+DINEC +
Sbjct: 310 MMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHL 369
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRCDCP 524
CP+ GRCVNL+G ++C C GY + CVD DEC+ G C+ C N G Y C C
Sbjct: 370 CPN-GRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQ 428
Query: 525 VGTVRSP 545
G P
Sbjct: 429 PGFALMP 435
Score = 130 bits (313), Expect = 4e-30
Identities = 65/180 (36%), Positives = 88/180 (48%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
NT GS+RC C PG++ P +EC + C C N G Y C C GY
Sbjct: 335 NTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTP 394
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPS 356
D C D+DEC C+ C+N+EGSYECSC+ G+ D +C DI+EC +
Sbjct: 395 DRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICD 454
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC-QAPCRNYAGGYRCDCPVG 530
G+C N+ G +RC+C G+ + CVD +EC C C N G + C C +G
Sbjct: 455 GGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMG 514
Score = 126 bits (304), Expect = 5e-29
Identities = 72/188 (38%), Positives = 89/188 (47%), Gaps = 10/188 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA---GRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYEL 176
VNT G F C C GY + DEC P C +CHNT+GSY C C G++L
Sbjct: 291 VNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQL 350
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECH-EEG 344
+ + C D++ECE H C C N G Y+C+C GY D CVDI+EC G
Sbjct: 351 SPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNG 410
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQ-APCRNYAGGYRCD 518
C + C N GS+ C C G+ L + C D DEC C C N G YRC
Sbjct: 411 GCET--FCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCL 468
Query: 519 CPVGTVRS 542
C G + S
Sbjct: 469 CYDGFMAS 476
Score = 122 bits (293), Expect = 1e-27
Identities = 60/161 (37%), Positives = 84/161 (52%), Gaps = 7/161 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNT 257
+EC + P C C NT GS+ C C +G+ LD + NC D+DEC C + C NT
Sbjct: 234 NECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNT 293
Query: 258 EGSYECSCEDGYEK---RGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAE 428
G +EC C++GYE C+DI+EC + + G C N GS+RC CP G++L
Sbjct: 294 PGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPN 353
Query: 429 GARCVDRDECAQTGR-C-QAPCRNYAGGYRCDCPVGTVRSP 545
+ C+D +EC + C C N G Y+C C G +P
Sbjct: 354 ISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTP 394
Score = 121 bits (291), Expect = 2e-27
Identities = 59/143 (41%), Positives = 77/143 (53%), Gaps = 6/143 (4%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
R VN IG ++C C PGY P DEC++ C+ C N++GSY+C C+ G+ L
Sbjct: 374 RCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFAL 433
Query: 177 DEDGANCRDVDECERDTHTCQ-QICSNTEGSYECSCEDGYEKRGD--ACVDINECH-EEG 344
D +C D+DECE + + C C+N G Y C C DG+ D CVD+NEC
Sbjct: 434 MPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPN 493
Query: 345 VCPSPGRCVNLLGSFRCVCPRGY 413
+C S G C N GSF C C GY
Sbjct: 494 ICLS-GTCENTKGSFICHCDMGY 515
Score = 87.4 bits (207), Expect = 3e-17
Identities = 57/179 (31%), Positives = 79/179 (44%), Gaps = 7/179 (3%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVR-PPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C C G A G +EC +R P ++LC G E+ +D++
Sbjct: 184 CCCSVG---AAWGTEECEECPMRNTPEYEELCPRGPGF------ATKEITNGKPFFKDIN 234
Query: 210 ECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLL 380
EC+ C C NT GS++C C+ G+ + C DI+EC G+CVN
Sbjct: 235 ECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTP 294
Query: 381 GSFRCVCPRGYRLDAEGAR-CVDRDECAQTGR-CQAP-CRNYAGGYRCDCPVGTVRSPS 548
G F C C GY + C+D DEC + C+ C N G YRC+CP G SP+
Sbjct: 295 GDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPN 353
Score = 63.3 bits (147), Expect = 5e-10
Identities = 54/184 (29%), Positives = 74/184 (40%), Gaps = 10/184 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGR---GVRGRDECAVR--PPPCDQLCHNTDGSYDCLCRTG 167
VNT GSF+C C G GR +R + C +R C C C G
Sbjct: 131 VNTRGSFKCQCPSGMTLDATGRICLDIR-LETCFLRYEDEECTLPIAGRHRMDACCCSVG 189
Query: 168 YELDEDGANCRDVDECE-RDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEG 344
+ + +EC R+T +++C G +G DINEC
Sbjct: 190 AAWGTE-----ECEECPMRNTPEYEELCPRGPGFATKEITNG----KPFFKDINECKMIP 240
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC-QAPCRNYAGGYRCD 518
+ G+C N +GSF+C C G+ LD+E C D DEC C + C N G + C
Sbjct: 241 SLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECK 300
Query: 519 CPVG 530
C G
Sbjct: 301 CDEG 304
Score = 61.3 bits (142), Expect = 2e-09
Identities = 47/139 (33%), Positives = 66/139 (47%), Gaps = 26/139 (18%)
Frame = +3
Query: 108 PC-DQLCHNTDGSYDCLCRTGYELDEDGANCRD----------VD-ECERDTHTC---QQ 242
PC + +C N+ GS+ C C + LD C + +D CE + + Q
Sbjct: 19 PCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQ 78
Query: 243 ICSNTEGSY--ECS-------CEDGYEK-RGDACVDINECHE-EGVCPSPGRCVNLLGSF 389
CS+ ++ C+ C GY + +G C DI+EC GVC + G CVN GSF
Sbjct: 79 CCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKN-GLCVNTRGSF 137
Query: 390 RCVCPRGYRLDAEGARCVD 446
+C CP G LDA G C+D
Sbjct: 138 KCQCPSGMTLDATGRICLD 156
Score = 54.8 bits (126), Expect = 2e-07
Identities = 52/178 (29%), Positives = 66/178 (37%), Gaps = 13/178 (7%)
Frame = +3
Query: 36 VCGPGY-RPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDV- 206
+CG GY R G DEC V P C LC NT GS+ C C +G LD G C D+
Sbjct: 99 ICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIR 158
Query: 207 -DEC--ERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNL 377
+ C + C + C C G A EC E CP +
Sbjct: 159 LETCFLRYEDEECTLPIAGRHRMDACCCSVG------AAWGTEECEE---CP-----MRN 204
Query: 378 LGSFRCVCPRGYRLDAEGAR-----CVDRDECAQ-TGRC-QAPCRNYAGGYRCDCPVG 530
+ +CPRG + D +EC C CRN G ++C C G
Sbjct: 205 TPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSG 262
>AK027344-1|BAB55049.1| 741|Homo sapiens protein ( Homo sapiens
cDNA FLJ14438 fis, clone HEMBB1000317, weakly similar to
FIBULIN-1, ISOFORM D PRECURSOR. ).
Length = 741
Score = 157 bits (380), Expect = 3e-38
Identities = 80/181 (44%), Positives = 98/181 (54%), Gaps = 8/181 (4%)
Frame = +3
Query: 12 NTIGSFRCV--CGPGYRPAGRGVRGRD--ECAVRPPPCDQLCHNTDGSYDCLCRTGYELD 179
NTIGS+RCV CG G+R G+ +D EC PC Q C N GS+ C C GY+L
Sbjct: 389 NTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQRCFNAIGSFHCGCEPGYQLK 447
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECS--CEDGYEK-RGDACVDINECHE-EGV 347
G C DV+EC ++ Q C NT G Y+C C +G K C+DI+EC +
Sbjct: 448 --GRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQ 505
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPV 527
C C N GS+RCVCPRGYR G C+D DEC T CQ C+N G Y+C CP
Sbjct: 506 CRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDIDECENTDACQHECKNTFGSYQCICPP 565
Query: 528 G 530
G
Sbjct: 566 G 566
Score = 149 bits (362), Expect = 5e-36
Identities = 82/193 (42%), Positives = 96/193 (49%), Gaps = 12/193 (6%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDC--LCRTGYEL 176
R N IGSF C C PGY+ GR +EC DQ C NT G Y C LC G
Sbjct: 428 RCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTK 487
Query: 177 DEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKR--GDACVDINECHEEG 344
E+G C D+DEC+ TH C+ QIC NT GSY C C GY + G C+DI+EC
Sbjct: 488 AENG-TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDIDECENTD 546
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC--QAPCRNYAGGYRC 515
C C N GS++C+CP GY+L G C D DEC Q C C N G Y+C
Sbjct: 547 ACQH--ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQC 604
Query: 516 ---DCPVGTVRSP 545
CP R P
Sbjct: 605 IDTPCPPNYQRDP 617
Score = 138 bits (335), Expect = 9e-33
Identities = 75/185 (40%), Positives = 94/185 (50%), Gaps = 9/185 (4%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRD 203
S +C G G DECA P C CHN G+Y C C G + DG C+D
Sbjct: 312 SNQCPSGFTLDSVGPFCADEDECAAGNP-CSHSCHNAMGTYYCSCPKGLTIAADGRTCQD 370
Query: 204 VDECERDTHTCQ--QICSNTEGSYEC--SCEDGYEKRGD--ACVDINECHEEGVCPSPGR 365
+DEC HTC Q C NT GSY C C G+ + D +C DINEC E C R
Sbjct: 371 IDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQ--R 428
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGRCQAPCRNYAGGYRCD--CPVGTV 536
C N +GSF C C GY+L +G +C+D +EC Q R C+N GGY+C CP G
Sbjct: 429 CFNAIGSFHCGCEPGYQL--KGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMT 486
Query: 537 RSPSG 551
++ +G
Sbjct: 487 KAENG 491
>AB177802-1|BAD16738.1| 1365|Homo sapiens fibrillin 1 protein.
Length = 1365
Score = 157 bits (380), Expect = 3e-38
Identities = 79/187 (42%), Positives = 101/187 (54%), Gaps = 9/187 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD- 179
NTIGSF+C C G+ R DEC + P C + C NT G ++C C GYE
Sbjct: 1046 NTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGF 1105
Query: 180 EDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEG-V 347
NC D+DEC+RD C+ +C NTEGSY C C G++ + AC+DINEC +
Sbjct: 1106 MMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHL 1165
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRCDCP 524
CP+ GRCVNL+G ++C C GY + CVD DEC+ G C+ C N G Y C C
Sbjct: 1166 CPN-GRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQ 1224
Query: 525 VGTVRSP 545
G P
Sbjct: 1225 PGFALMP 1231
Score = 139 bits (337), Expect = 5e-33
Identities = 72/187 (38%), Positives = 94/187 (50%), Gaps = 9/187 (4%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
R VN IG ++C C PGY P DEC++ C+ C N++GSY+C C+ G+ L
Sbjct: 1170 RCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFAL 1229
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECH-EEG 344
D +C D+DECE + + C C+N G Y C C DG+ D CVD+NEC
Sbjct: 1230 MPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPN 1289
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC---AQTGRCQAPCRNYAGGYRC 515
+C S G C N GSF C C GY C D +EC A A C N AG ++C
Sbjct: 1290 ICLS-GTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKC 1348
Query: 516 DCPVGTV 536
C G +
Sbjct: 1349 SCSPGWI 1355
Score = 135 bits (327), Expect = 8e-32
Identities = 69/178 (38%), Positives = 94/178 (52%), Gaps = 5/178 (2%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRG-VRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELD 179
R + T GS RC C G++ RG DEC P + C N GSY C CR GY+
Sbjct: 464 RCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPCAGGE-CINNQGSYTCQCRAGYQST 522
Query: 180 EDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVC 350
CRD+DEC ++ C C NT+GS+ C C G+ + G C D++EC +C
Sbjct: 523 LTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMC 582
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDC 521
+ G C+N GSF+C+C G++L ++G C D +EC G C C N G YRC+C
Sbjct: 583 LN-GMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCEC 639
Score = 130 bits (313), Expect = 4e-30
Identities = 65/180 (36%), Positives = 88/180 (48%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
NT GS+RC C PG++ P +EC + C C N G Y C C GY
Sbjct: 1131 NTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTP 1190
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPS 356
D C D+DEC C+ C+N+EGSYECSC+ G+ D +C DI+EC +
Sbjct: 1191 DRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICD 1250
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC-QAPCRNYAGGYRCDCPVG 530
G+C N+ G +RC+C G+ + CVD +EC C C N G + C C +G
Sbjct: 1251 GGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMG 1310
Score = 127 bits (307), Expect = 2e-29
Identities = 67/182 (36%), Positives = 90/182 (49%), Gaps = 11/182 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD 179
+N GS+ C C GY+ RD EC C+ C NTDGS+ C+C G+ +
Sbjct: 505 INNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVT 564
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCP 353
DG NC D+DEC +C N +GS++C C+ G++ D C DINEC G+C
Sbjct: 565 RDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICM 624
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVD---RDEC---AQTGRCQAPCRNYAGGYRC 515
+ GRCVN GS+RC C G + +G CVD R C + G+C P C
Sbjct: 625 N-GRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSEC 683
Query: 516 DC 521
C
Sbjct: 684 CC 685
Score = 126 bits (304), Expect = 5e-29
Identities = 72/188 (38%), Positives = 89/188 (47%), Gaps = 10/188 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA---GRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYEL 176
VNT G F C C GY + DEC P C +CHNT+GSY C C G++L
Sbjct: 1087 VNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQL 1146
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECH-EEG 344
+ + C D++ECE H C C N G Y+C+C GY D CVDI+EC G
Sbjct: 1147 SPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNG 1206
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQ-APCRNYAGGYRCD 518
C + C N GS+ C C G+ L + C D DEC C C N G YRC
Sbjct: 1207 GCET--FCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCL 1264
Query: 519 CPVGTVRS 542
C G + S
Sbjct: 1265 CYDGFMAS 1272
Score = 122 bits (293), Expect = 1e-27
Identities = 60/161 (37%), Positives = 84/161 (52%), Gaps = 7/161 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNT 257
+EC + P C C NT GS+ C C +G+ LD + NC D+DEC C + C NT
Sbjct: 1030 NECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNT 1089
Query: 258 EGSYECSCEDGYEK---RGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAE 428
G +EC C++GYE C+DI+EC + + G C N GS+RC CP G++L
Sbjct: 1090 PGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPN 1149
Query: 429 GARCVDRDECAQTGR-C-QAPCRNYAGGYRCDCPVGTVRSP 545
+ C+D +EC + C C N G Y+C C G +P
Sbjct: 1150 ISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTP 1190
Score = 113 bits (272), Expect = 4e-25
Identities = 56/139 (40%), Positives = 73/139 (52%), Gaps = 3/139 (2%)
Frame = +3
Query: 123 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR 302
C T GS C C G++LD G C DVDECE++ + C N +GSY C C GY+
Sbjct: 465 CIPTPGSCRCECNKGFQLDLRG-ECIDVDECEKNPCAGGE-CINNQGSYTCQCRAGYQST 522
Query: 303 --GDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC 476
C DI+EC + G + GRC+N GSF CVC G+ + +G C D DEC+ C
Sbjct: 523 LTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMC 582
Query: 477 -QAPCRNYAGGYRCDCPVG 530
C N G ++C C G
Sbjct: 583 LNGMCINEDGSFKCICKPG 601
Score = 109 bits (261), Expect = 8e-24
Identities = 61/158 (38%), Positives = 83/158 (52%), Gaps = 9/158 (5%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C GPG AG + +ECA+ P C +C N G+Y C+C +GYE+D G NC D++
Sbjct: 711 CSSGPGMTSAGSDI---NECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDIN 767
Query: 210 ECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLL 380
EC ++ C C NT GS+ C+C G+ + D C DI+EC E C + G C N
Sbjct: 768 ECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDEC-ESSPCIN-GVCKNSP 825
Query: 381 GSFRCVCPRGYRLDAEGARCVD--RDECAQT---GRCQ 479
GSF C C LD C++ + C QT GRC+
Sbjct: 826 GSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCE 863
Score = 103 bits (248), Expect = 3e-22
Identities = 51/150 (34%), Positives = 69/150 (46%), Gaps = 3/150 (2%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCE 284
PC Y LC +G + G+ D++EC D C IC N G+Y+C C
Sbjct: 695 PCQPCPAQNSAEYQALCSSGPGMTSAGS---DINECALDPDICPNGICENLRGTYKCICN 751
Query: 285 DGYE--KRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC 458
GYE G CVDINEC + G+C N GSF C CP+G+ + C D DEC
Sbjct: 752 SGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDEC 811
Query: 459 AQTGRCQAPCRNYAGGYRCDCPVGTVRSPS 548
+ C+N G + C+C + P+
Sbjct: 812 ESSPCINGVCKNSPGSFICECSSESTLDPT 841
Score = 96.7 bits (230), Expect = 5e-20
Identities = 44/110 (40%), Positives = 60/110 (54%), Gaps = 4/110 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
R +NT GSF CVC G+ G+ DEC++R + +C N DGS+ C+C+ G++L
Sbjct: 545 RCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQL 604
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVD 320
DG C+D++ECE C NT+GSY C C G G CVD
Sbjct: 605 ASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVD 654
Score = 87.4 bits (207), Expect = 3e-17
Identities = 57/179 (31%), Positives = 79/179 (44%), Gaps = 7/179 (3%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVR-PPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C C G A G +EC +R P ++LC G E+ +D++
Sbjct: 980 CCCSVG---AAWGTEECEECPMRNTPEYEELCPRGPGF------ATKEITNGKPFFKDIN 1030
Query: 210 ECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLL 380
EC+ C C NT GS++C C+ G+ + C DI+EC G+CVN
Sbjct: 1031 ECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTP 1090
Query: 381 GSFRCVCPRGYRLDAEGAR-CVDRDECAQTGR-CQAP-CRNYAGGYRCDCPVGTVRSPS 548
G F C C GY + C+D DEC + C+ C N G YRC+CP G SP+
Sbjct: 1091 GDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPN 1149
Score = 85.0 bits (201), Expect = 2e-16
Identities = 61/209 (29%), Positives = 91/209 (43%), Gaps = 29/209 (13%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
N G+++C+C GY G+ +EC + CD C NT GS+ C C G+
Sbjct: 741 NLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKP 800
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSY--ECSCEDGYEKRGDACVDI--NECHE---E 341
D C D+DECE + +C N+ GS+ ECS E + C++ C + +
Sbjct: 801 DLKTCEDIDECE-SSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVID 859
Query: 342 GVC-------PSPGRCVNLLGS---FRC-------VCPRGYRLDAEGARCVDRDEC-AQT 467
G C +C + LG+ C +C +GY +G +C D DEC
Sbjct: 860 GRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYS-RIKGTQCEDIDECEVFP 918
Query: 468 GRCQ-APCRNYAGGYRCDCPVGTVRSPSG 551
G C+ C N G ++C CP G +G
Sbjct: 919 GVCKNGLCVNTRGSFKCQCPSGMTLDATG 947
Score = 83.4 bits (197), Expect = 5e-16
Identities = 49/139 (35%), Positives = 64/139 (46%), Gaps = 9/139 (6%)
Frame = +3
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKR--GDACVDIN 326
CR G+ + C+DVDEC+ CQ C NT GS+EC C G++ C DI+
Sbjct: 231 CRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDID 290
Query: 327 ECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD-RDECAQT----GRCQAPC 488
EC G+C G C N + S+ C CP G+ +G RC+D R T GRC
Sbjct: 291 ECSTIPGICEG-GECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQL 349
Query: 489 RNYAGGYRCDCPVGTVRSP 545
+C C G SP
Sbjct: 350 PQSITKMQCCCDAGRCWSP 368
Score = 80.2 bits (189), Expect = 4e-15
Identities = 38/110 (34%), Positives = 56/110 (50%), Gaps = 5/110 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDE 182
N G +RC+C G+ + + +EC + P C C NT GS+ C C GY +
Sbjct: 1256 NIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKK 1315
Query: 183 DGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGDACVDIN 326
C D++ECE H C +C+NT GS++CSC G+ G C D++
Sbjct: 1316 GKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLD 1365
Score = 77.0 bits (181), Expect = 4e-14
Identities = 60/173 (34%), Positives = 81/173 (46%), Gaps = 28/173 (16%)
Frame = +3
Query: 12 NTIGSFRCVCGPG--YRPAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDE 182
NT GSF C C G Y+P + DEC PC + +C N+ GS+ C C + LD
Sbjct: 783 NTPGSFVCTCPKGFIYKPDLKTCEDIDEC--ESSPCINGVCKNSPGSFICECSSESTLDP 840
Query: 183 DGANCRD----------VD-ECERDTHTC---QQICSNTEGSY--ECS-------CEDGY 293
C + +D CE + + Q CS+ ++ C+ C GY
Sbjct: 841 TKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGY 900
Query: 294 EK-RGDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
+ +G C DI+EC GVC + G CVN GSF+C CP G LDA G C+D
Sbjct: 901 SRIKGTQCEDIDECEVFPGVCKN-GLCVNTRGSFKCQCPSGMTLDATGRICLD 952
Score = 76.6 bits (180), Expect = 5e-14
Identities = 36/87 (41%), Positives = 47/87 (54%), Gaps = 3/87 (3%)
Frame = +3
Query: 300 RGDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGR 473
R AC D++EC G+C G C+N +GSF C CP G++L+ +C D DEC+ G
Sbjct: 240 RTGACQDVDECQAIPGLCQG-GNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGI 298
Query: 474 CQ-APCRNYAGGYRCDCPVGTVRSPSG 551
C+ C N Y C CP G SP G
Sbjct: 299 CEGGECTNTVSSYFCKCPPGFYTSPDG 325
Score = 69.3 bits (162), Expect = 8e-12
Identities = 41/119 (34%), Positives = 55/119 (46%), Gaps = 10/119 (8%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ-QICSNT 257
DEC P C C NT GS++C C G++L+E C D+DEC C+ C+NT
Sbjct: 248 DECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNT 307
Query: 258 EGSYECSCEDGY--EKRGDACVDINE--CHEEGVCPSPGRCVNLL----GSFRCVCPRG 410
SY C C G+ G C+D+ C+ + GRC N L +C C G
Sbjct: 308 VSSYFCKCPPGFYTSPDGTRCIDVRPGYCY---TALTNGRCSNQLPQSITKMQCCCDAG 363
Score = 63.3 bits (147), Expect = 5e-10
Identities = 54/184 (29%), Positives = 74/184 (40%), Gaps = 10/184 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGR---GVRGRDECAVR--PPPCDQLCHNTDGSYDCLCRTG 167
VNT GSF+C C G GR +R + C +R C C C G
Sbjct: 927 VNTRGSFKCQCPSGMTLDATGRICLDIR-LETCFLRYEDEECTLPIAGRHRMDACCCSVG 985
Query: 168 YELDEDGANCRDVDECE-RDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEG 344
+ + +EC R+T +++C G +G DINEC
Sbjct: 986 AAWGTE-----ECEECPMRNTPEYEELCPRGPGFATKEITNG----KPFFKDINECKMIP 1036
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC-QAPCRNYAGGYRCD 518
+ G+C N +GSF+C C G+ LD+E C D DEC C + C N G + C
Sbjct: 1037 SLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECK 1096
Query: 519 CPVG 530
C G
Sbjct: 1097 CDEG 1100
Score = 56.4 bits (130), Expect = 6e-08
Identities = 24/57 (42%), Positives = 30/57 (52%)
Frame = +3
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
GRC+ GS RC C +G++LD G C+D DEC + C N G Y C C G
Sbjct: 463 GRCIPTPGSCRCECNKGFQLDLRG-ECIDVDECEKNPCAGGECINNQGSYTCQCRAG 518
Score = 55.6 bits (128), Expect = 1e-07
Identities = 40/135 (29%), Positives = 51/135 (37%), Gaps = 4/135 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCD-QLCHNTDGSYDCLCRTGYELD 179
+NT+GSF C C G++ + DEC+ P C+ C NT SY C C G+
Sbjct: 263 INTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTS 322
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSP 359
DG C DV T CSN K C D C GV +P
Sbjct: 323 PDGTRCIDVRPGYCYTALTNGRCSN-------QLPQSITKM-QCCCDAGRCWSPGVTVAP 374
Query: 360 GRC-VNLLGSFRCVC 401
C + F +C
Sbjct: 375 EMCPIRATEDFNKLC 389
Score = 54.8 bits (126), Expect = 2e-07
Identities = 52/178 (29%), Positives = 66/178 (37%), Gaps = 13/178 (7%)
Frame = +3
Query: 36 VCGPGY-RPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDV- 206
+CG GY R G DEC V P C LC NT GS+ C C +G LD G C D+
Sbjct: 895 ICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIR 954
Query: 207 -DEC--ERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNL 377
+ C + C + C C G A EC E CP +
Sbjct: 955 LETCFLRYEDEECTLPIAGRHRMDACCCSVG------AAWGTEECEE---CP-----MRN 1000
Query: 378 LGSFRCVCPRGYRLDAEGAR-----CVDRDECAQ-TGRC-QAPCRNYAGGYRCDCPVG 530
+ +CPRG + D +EC C CRN G ++C C G
Sbjct: 1001 TPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSG 1058
Score = 33.9 bits (74), Expect = 0.38
Identities = 40/144 (27%), Positives = 56/144 (38%), Gaps = 6/144 (4%)
Frame = +3
Query: 3 RGVNTIGS-FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYD--CLCRTGYE 173
+G N GS + C PG++ + G ++C V P C C + S C C +G
Sbjct: 54 KGPNVCGSRYNAYCCPGWKT----LPGGNQCIV--PICRHSCGDGFCSRPNMCTCPSGQI 107
Query: 174 LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC---VDINECHEEG 344
G+ R + C C S ++ C C+ GY G C V + C G
Sbjct: 108 APSCGS--RSIQHCNI---RCMNGGSCSDD--HCLCQKGYI--GTHCGQPVCESGCLNGG 158
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYR 416
C +P RC G C R YR
Sbjct: 159 RCVAPNRCACTYGFTGPQCERDYR 182
>AB208840-1|BAD92077.1| 830|Homo sapiens fibrillin 1 variant
protein.
Length = 830
Score = 152 bits (368), Expect = 9e-37
Identities = 75/180 (41%), Positives = 100/180 (55%), Gaps = 6/180 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRG-VRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
+NT GS+RC C PGYR G R+EC P C C +T GS+ CLC TG++ ++
Sbjct: 260 INTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTND 319
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY-EKRGDACVDINECHE-EGVCPS 356
D C D++ECERD C NT GS+ C C G+ + C+D++EC G
Sbjct: 320 DQTMCLDINECERDA-CGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCR 378
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRCDCPVG 530
G+C+N +GSF+C C GY + +G CVD +EC R AP C+N G YRC CP G
Sbjct: 379 NGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPG 438
Score = 137 bits (332), Expect = 2e-32
Identities = 71/186 (38%), Positives = 94/186 (50%), Gaps = 6/186 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+NT GS+RC C GY AG DEC+V P + C N G ++C C G+E
Sbjct: 578 INTDGSYRCECPFGYILAGNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFE-PGPM 636
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHE--EGVCPS 356
C D++EC ++ C C NT GSYEC C GY R D C D +EC E
Sbjct: 637 MTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEK 696
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQ-APCRNYAGGYRCDCPVG 530
C NL+G++ C+C GY+ +G CVD +EC + G C+ C N G Y C+C G
Sbjct: 697 QMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDG 756
Query: 531 TVRSPS 548
SP+
Sbjct: 757 FTASPN 762
Score = 136 bits (328), Expect = 6e-32
Identities = 75/188 (39%), Positives = 98/188 (52%), Gaps = 7/188 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDED 185
++T+GSF C+C G++ D C C NT GS++C C G+ L +
Sbjct: 301 IDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHN 360
Query: 186 GANCRDVDECERDT-HTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCP 353
+C DVDEC + C+ C NT GS++C C +GYE D CVDINEC E
Sbjct: 361 N-DCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKC 419
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQA--PCRNYAGGYRCDCPV 527
+PG C NL GS+RC+CP GY L E +C D DEC + A C N G ++C CP
Sbjct: 420 APGTCQNLDGSYRCICPPGYSLQNE--KCEDIDECVEEPEICALGTCSNTEGSFKCLCPE 477
Query: 528 GTVRSPSG 551
G S SG
Sbjct: 478 GFSLSSSG 485
Score = 128 bits (310), Expect = 1e-29
Identities = 64/152 (42%), Positives = 79/152 (51%), Gaps = 7/152 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGV-RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
N IG F C C G+ P +ECA P C C NT GSY+C C GY L ED
Sbjct: 618 NVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDR 677
Query: 189 ANCRDVDECERDTHTC---QQICSNTEGSYECSCEDGYEKR--GDACVDINECH-EEGVC 350
C+D DECE H C Q C N G+Y C C GY++R G+ CVD NEC + G+C
Sbjct: 678 RMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGIC 737
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
+ GRC+N GS+ C C G+ C+D
Sbjct: 738 EN-GRCLNTRGSYTCECNDGFTASPNQDECLD 768
Score = 126 bits (304), Expect = 5e-29
Identities = 68/179 (37%), Positives = 88/179 (49%), Gaps = 9/179 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA-GRGVRGRDECAV-RPPPC-DQLCHNTDGSYDCLCRTGYELDE 182
NTIGSF C C G+ + DECA C + C NT GS+ C C GYE+
Sbjct: 342 NTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAP 401
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSP 359
DG C D++EC + C C N +GSY C C GY + + C DI+EC EE +
Sbjct: 402 DGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEICAL 461
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVD--RDEC---AQTGRCQAPCRNYAGGYRCDC 521
G C N GSF+C+CP G+ L + G RC D C + G+C +P C C
Sbjct: 462 GTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCC 520
Score = 117 bits (282), Expect = 2e-26
Identities = 72/191 (37%), Positives = 93/191 (48%), Gaps = 10/191 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPG--YRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYEL 176
+N +GSFRC C G Y DEC P C + C NT GSY C C+ GY
Sbjct: 218 INMVGSFRCECPVGFFYNDKLLVCEDIDECQ-NGPVCQRNAECINTAGSYRCDCKPGYRF 276
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGV 347
G C D +EC+ + C C +T GS+ C C G++ D C+DINEC E
Sbjct: 277 TSTG-QCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINEC-ERDA 334
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGR-CQ-APCRNYAGGYRCD 518
C + G C N +GSF C C G+ L + C+D DECA G C+ C N G ++C
Sbjct: 335 CGN-GTCRNTIGSFNCRCNHGFIL-SHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQ 392
Query: 519 CPVGTVRSPSG 551
C G +P G
Sbjct: 393 CNEGYEVAPDG 403
Score = 116 bits (279), Expect = 6e-26
Identities = 67/162 (41%), Positives = 78/162 (48%), Gaps = 6/162 (3%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTE 260
DEC P C C NTDGSY C C GY L G C D DEC C N
Sbjct: 564 DECK-EPDVCKHGQCINTDGSYRCECPFGYILA--GNECVDTDECSVGNPCGNGTCKNVI 620
Query: 261 GSYECSCEDGYEKRGD-ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGAR 437
G +EC+CE+G+E C DINEC + + + RCVN GS+ C CP GY L +
Sbjct: 621 GGFECTCEEGFEPGPMMTCEDINECAQNPLLCA-FRCVNTYGSYECKCPVGYVLREDRRM 679
Query: 438 CVDRDECAQTGR-C---QAPCRNYAGGYRCDCPVGTVRSPSG 551
C D DEC + C Q C+N G Y C C G R P G
Sbjct: 680 CKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDG 721
Score = 113 bits (273), Expect = 3e-25
Identities = 57/158 (36%), Positives = 82/158 (51%), Gaps = 5/158 (3%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQI--CSN 254
DEC P C+ +C N GS+ C C G+ ++ C D+DEC+ CQ+ C N
Sbjct: 203 DECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGP-VCQRNAECIN 261
Query: 255 TEGSYECSCEDGYEKRGDA-CVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAE 428
T GSY C C+ GY C D NEC E +C S G+C++ +GSF C+C G++ + +
Sbjct: 262 TAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNIC-SHGQCIDTVGSFYCLCHTGFKTNDD 320
Query: 429 GARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVRS 542
C+D +EC + CRN G + C C G + S
Sbjct: 321 QTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILS 358
Score = 94.7 bits (225), Expect = 2e-19
Identities = 53/147 (36%), Positives = 69/147 (46%), Gaps = 4/147 (2%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCRTGYEL---DEDGANCRDVDECERDTHTCQQICSNTEGSYECS 278
PC+ D ++ +C G + +D A D+DEC+ C NT+GSY C
Sbjct: 530 PCELCPTEPDEAFRQICPYGSGIIVGPDDSAV--DMDECKEPDVCKHGQCINTDGSYRCE 587
Query: 279 CEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC 458
C GY G+ CVD +EC C + G C N++G F C C G+ C D +EC
Sbjct: 588 CPFGYILAGNECVDTDECSVGNPCGN-GTCKNVIGGFECTCEEGFE-PGPMMTCEDINEC 645
Query: 459 AQTG-RCQAPCRNYAGGYRCDCPVGTV 536
AQ C C N G Y C CPVG V
Sbjct: 646 AQNPLLCAFRCVNTYGSYECKCPVGYV 672
Score = 84.2 bits (199), Expect = 3e-16
Identities = 44/115 (38%), Positives = 56/115 (48%), Gaps = 8/115 (6%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQL---CHNTDGSYDCLCRTG 167
R VNT GS+ C C GY R R + DEC C + C N G+Y C+C G
Sbjct: 655 RCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPG 714
Query: 168 YELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGY--EKRGDACVDI 323
Y+ DG C D +EC+ C+ C NT GSY C C DG+ D C+D+
Sbjct: 715 YQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDV 769
Score = 80.6 bits (190), Expect = 3e-15
Identities = 41/118 (34%), Positives = 55/118 (46%), Gaps = 5/118 (4%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCR--TGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECS 278
PC+ Y LC G+ + D+DEC+ CQ C NT GS++C
Sbjct: 8 PCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCR 67
Query: 279 CEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
C GY D C D+NEC G+C PG C N +G++ C+CP Y G C+D
Sbjct: 68 CPTGYYLNEDTRVCDDVNECETPGIC-GPGTCYNTVGNYTCICPPDYMQVNGGNNCMD 124
Score = 77.4 bits (182), Expect = 3e-14
Identities = 57/183 (31%), Positives = 78/183 (42%), Gaps = 10/183 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDE----CAVRPPPCDQLCHNT--DGSYDCLCRTGYE 173
NT+G++ C+C P Y G D C +Q C +C Y
Sbjct: 100 NTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYN 159
Query: 174 LDEDGANCRDVDECE-RDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHE-EGV 347
+ A + ++C T +C + + G VDI+EC E GV
Sbjct: 160 IGR--AWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLP------VDIDECREIPGV 211
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ--APCRNYAGGYRCDC 521
C + G C+N++GSFRC CP G+ + + C D DEC CQ A C N AG YRCDC
Sbjct: 212 CEN-GVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDC 270
Query: 522 PVG 530
G
Sbjct: 271 KPG 273
Score = 70.1 bits (164), Expect = 5e-12
Identities = 44/112 (39%), Positives = 56/112 (50%), Gaps = 7/112 (6%)
Frame = +3
Query: 9 VNTIGSFRCVC--GPGYRPAGRGV--RGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYE 173
VNT ++ +C G G+RP V DEC P C C NT GS+ C C TGY
Sbjct: 15 VNT-SEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYY 73
Query: 174 LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEK--RGDACVDI 323
L+ED C DV+ECE C NT G+Y C C Y + G+ C+D+
Sbjct: 74 LNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDM 125
Score = 68.9 bits (161), Expect = 1e-11
Identities = 32/71 (45%), Positives = 40/71 (56%), Gaps = 2/71 (2%)
Frame = +3
Query: 318 DINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCR 491
DI+EC E G+C G+C+N GSF+C CP GY L+ + C D +EC G C C
Sbjct: 41 DIDECQELPGLCQG-GKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCY 99
Query: 492 NYAGGYRCDCP 524
N G Y C CP
Sbjct: 100 NTVGNYTCICP 110
Score = 33.5 bits (73), Expect = 0.50
Identities = 18/52 (34%), Positives = 26/52 (50%), Gaps = 4/52 (7%)
Frame = +3
Query: 387 FRCVCP--RGYRLDAEGARCVDRDECAQT-GRCQA-PCRNYAGGYRCDCPVG 530
++ +CP G+R + D DEC + G CQ C N G ++C CP G
Sbjct: 20 YKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTG 71
>BC008761-1|AAH08761.2| 743|Homo sapiens LTBP3 protein protein.
Length = 743
Score = 151 bits (365), Expect = 2e-36
Identities = 79/180 (43%), Positives = 95/180 (52%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCV-CGPGYRPAGRGV-RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
N GSF+C+ C PGYR G G R +ECA P C N GS+ C C GY D
Sbjct: 207 NKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPD 266
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCPSP 359
G +C DVDECE ICSNT GS++C C GY D C DI+EC C
Sbjct: 267 GRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIG- 325
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP---CRNYAGGYRCDCPVG 530
G C+N GS+RC+CP+G+RL G +C D DEC+Q P C+N G Y C C G
Sbjct: 326 GDCINTNGSYRCLCPQGHRL-VGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEG 384
Score = 135 bits (326), Expect = 1e-31
Identities = 77/185 (41%), Positives = 94/185 (50%), Gaps = 11/185 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR----PAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGY 170
+NT GS+ C C GYR GR +ECA +P C C N G Y C C GY
Sbjct: 120 MNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECA-KPHLCGDGGFCINFPGHYKCNCYPGY 178
Query: 171 ELDEDGAN-CRDVDECERDTHTCQQ-ICSNTEGSYEC-SCEDGYEKR-GDACVDINECHE 338
L C D+DEC RD +C C N GS++C +C+ GY + G AC D+NEC E
Sbjct: 179 RLKASRPPVCEDIDEC-RDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAE 237
Query: 339 EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRC 515
C SPG C NL GSFRC C +GY +G C+D DEC C C N G ++C
Sbjct: 238 GSPC-SPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQC 296
Query: 516 DCPVG 530
C G
Sbjct: 297 QCLSG 301
Score = 132 bits (318), Expect = 1e-30
Identities = 74/187 (39%), Positives = 93/187 (49%), Gaps = 12/187 (6%)
Frame = +3
Query: 27 FRCVCGPGYR--PAGRGVRGRDECAVRP-PPCDQLCHNTDGSYDCLCRTGYELD--EDGA 191
+ C C PGYR P R +EC P P +C NT GSY+C C GY L G
Sbjct: 84 YSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGR 143
Query: 192 NCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE---KRGDACVDINECHEEGVCPS 356
+C D++EC + H C C N G Y+C+C GY R C DI+EC + CP
Sbjct: 144 SCVDLNECAKP-HLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPD 202
Query: 357 PGRCVNLLGSFRCV-CPRGYRLDAEGARCVDRDECAQTGRCQAP-CRNYAGGYRCDCPVG 530
G+C N GSF+C+ C GYR GA C D +ECA+ C C N G +RC C G
Sbjct: 203 -GKCENKPGSFKCIACQPGYRSQGGGA-CRDVNECAEGSPCSPGWCENLPGSFRCTCAQG 260
Query: 531 TVRSPSG 551
+P G
Sbjct: 261 YAPAPDG 267
Score = 130 bits (313), Expect = 4e-30
Identities = 73/182 (40%), Positives = 91/182 (50%), Gaps = 8/182 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR-PAGRG--VRGRDECAVRPPPC-DQLCHNTDGSYDCL-CRTGYE 173
+N G ++C C PGYR A R DEC P C D C N GS+ C+ C+ GY
Sbjct: 164 INFPGHYKCNCYPGYRLKASRPPVCEDIDECR-DPSSCPDGKCENKPGSFKCIACQPGYR 222
Query: 174 LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR--GDACVDINECHEEGV 347
GA CRDV+EC + C N GS+ C+C GY G +C+D++EC V
Sbjct: 223 SQGGGA-CRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDV 281
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCP 524
C + G C N GSF+C C GY L + + C D DEC C C N G YRC CP
Sbjct: 282 CDN-GICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCP 340
Query: 525 VG 530
G
Sbjct: 341 QG 342
Score = 122 bits (293), Expect = 1e-27
Identities = 64/178 (35%), Positives = 85/178 (47%), Gaps = 4/178 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
N GSFRC C GY PA GR DEC + +C NT GS+ C C +GY L D
Sbjct: 248 NLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRD 307
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE-KRGDACVDINECHEE-GVCPSP 359
++C D+DEC+ C NT GSY C C G+ G C DI+EC ++ +C
Sbjct: 308 RSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPH 367
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGT 533
G C NL GS+ CVC G+ + C + ++ C N+ CD + T
Sbjct: 368 GACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYL---NFDDTVFCDSVLAT 422
Score = 104 bits (249), Expect = 2e-22
Identities = 59/164 (35%), Positives = 72/164 (43%), Gaps = 8/164 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDT-HTCQQICSNT 257
DEC + C C Y C C GY C DV+ECE + + IC NT
Sbjct: 63 DECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNT 122
Query: 258 EGSYECSCEDGYEKR----GDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDA 425
GSY C C GY G +CVD+NEC + +C G C+N G ++C C GYRL A
Sbjct: 123 GGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKA 182
Query: 426 EGAR-CVDRDECAQTGRC-QAPCRNYAGGYRCDCPVGTVRSPSG 551
C D DEC C C N G ++C RS G
Sbjct: 183 SRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGG 226
Score = 86.6 bits (205), Expect = 5e-17
Identities = 46/117 (39%), Positives = 57/117 (48%), Gaps = 7/117 (5%)
Frame = +3
Query: 201 DVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCPSPGRCV 371
+ DEC + + C C Y C C GY CVD+NEC E P G C+
Sbjct: 61 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICM 120
Query: 372 NLLGSFRCVCPRGYRL--DAEGARCVDRDECAQTGRC--QAPCRNYAGGYRCDCPVG 530
N GS+ C C RGYRL A G CVD +ECA+ C C N+ G Y+C+C G
Sbjct: 121 NTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPG 177
Score = 70.1 bits (164), Expect = 5e-12
Identities = 67/204 (32%), Positives = 86/204 (42%), Gaps = 24/204 (11%)
Frame = +3
Query: 12 NTIGSFRCVCGPG--YRPAGRGVRGRDECAVRPPPCDQLCHNTDGSY------------- 146
NT G +RC C P Y PA R +E R P +C + G
Sbjct: 540 NTRGGYRCACTPPAEYSPAQRQCLSPEEME-RAPERRDVCWSQRGEDGMCAGPLAGPALT 598
Query: 147 --DCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECS-CEDGYEKRGDACV 317
DC CR G GA CR +H C S + ++ S G R +
Sbjct: 599 FDDCCCRQGRGW---GAQCRPCPPRGAGSH-CPTSQSESNSFWDTSPLLLGKPPRDEDSS 654
Query: 318 DINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR----CQAP 485
+ E +E C S GRCV G C CP G++LDA ARCVD DEC + + C++
Sbjct: 655 E--EDSDECRCVS-GRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSE 711
Query: 486 -CRNYAGGYRCDCPVGTVRS-PSG 551
C N +G +RC C G RS P G
Sbjct: 712 RCVNTSGSFRCVCKAGFARSRPHG 735
Score = 67.7 bits (158), Expect = 3e-11
Identities = 58/194 (29%), Positives = 80/194 (41%), Gaps = 15/194 (7%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCH-NTDGSYDCLCRTGYELDEDG 188
N GS+ CVC G+ P + G +E V P + C+ N D + C + +
Sbjct: 372 NLQGSYVCVCDEGFTPT-QDQHGCEE--VEQPHHKKECYLNFDDTVFCDSVLATNVTQQE 428
Query: 189 ANCRDV----DECERDTHTCQQICSNTEGSYECSCEDGYEKRGD-------ACVDINECH 335
C D CE + C + S+ E C GY + + A DI+EC
Sbjct: 429 CCCSLGAGWGDHCE--IYPCP-VYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECM 485
Query: 336 EEG--VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ-APCRNYAGG 506
G +C G+CVN + C C +G+ D CVD DEC C+ C N GG
Sbjct: 486 LFGSEICKE-GKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGG 544
Query: 507 YRCDCPVGTVRSPS 548
YRC C SP+
Sbjct: 545 YRCACTPPAEYSPA 558
Score = 67.3 bits (157), Expect = 3e-11
Identities = 58/189 (30%), Positives = 76/189 (40%), Gaps = 15/189 (7%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR-PAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELD 179
+NT GS+RC+C G+R GR + DEC+ P C C N GSY C+C G+
Sbjct: 329 INTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPT 388
Query: 180 EDGANCRDVD------ECE---RDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINEC 332
+D C +V+ EC DT C + + EC C G GD C +I C
Sbjct: 389 QDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLG-AGWGDHC-EIYPC 446
Query: 333 HEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR--C-QAPCRNYAG 503
C + G + Y + A D DEC G C + C N
Sbjct: 447 PVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHR----DIDECMLFGSEICKEGKCVNTQP 502
Query: 504 GYRCDCPVG 530
GY C C G
Sbjct: 503 GYECYCKQG 511
Score = 62.9 bits (146), Expect = 7e-10
Identities = 49/168 (29%), Positives = 72/168 (42%), Gaps = 11/168 (6%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTG--YELDEDGANC--- 197
C C G AG G D C + P P + + LC G Y D + N
Sbjct: 429 CCCSLG---AGWG----DHCEIYPCPV-----YSSAEFHSLCPDGKGYTQDNNIVNYGIP 476
Query: 198 --RDVDECER-DTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCPSP 359
RD+DEC + C++ C NT+ YEC C+ G+ G+ CVD++EC +E C +
Sbjct: 477 AHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRN- 535
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAG 503
G C N G +RC C +C+ +E + + C + G
Sbjct: 536 GVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPERRDVCWSQRG 583
Score = 59.3 bits (137), Expect = 9e-09
Identities = 33/90 (36%), Positives = 41/90 (45%), Gaps = 8/90 (8%)
Frame = +3
Query: 198 RDVDECERDTHTCQQI---CSNTEGSYECSCEDGYEKRGDA--CVDINECHE---EGVCP 353
RD D E D+ C+ + C G C C G++ CVDI+EC E G+
Sbjct: 649 RDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLC 708
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCV 443
RCVN GSFRCVC G+ CV
Sbjct: 709 KSERCVNTSGSFRCVCKAGFARSRPHGACV 738
Score = 37.1 bits (82), Expect = 0.041
Identities = 24/87 (27%), Positives = 33/87 (37%), Gaps = 2/87 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VNT + C C G+ G + DEC + +C NT G Y C C E
Sbjct: 498 VNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSP 557
Query: 183 DGANCRDVDECERDTHTCQQICSNTEG 263
C +E ER + +C + G
Sbjct: 558 AQRQCLSPEEMERAPER-RDVCWSQRG 583
Score = 30.7 bits (66), Expect = 3.6
Identities = 17/30 (56%), Positives = 18/30 (60%), Gaps = 3/30 (10%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGY---RPAGRGVRGR 83
R VNT GSFRCVC G+ RP G V R
Sbjct: 712 RCVNTSGSFRCVCKAGFARSRPHGACVPQR 741
>AK024477-1|BAB15767.1| 1382|Homo sapiens FLJ00070 protein protein.
Length = 1382
Score = 151 bits (365), Expect = 2e-36
Identities = 79/180 (43%), Positives = 95/180 (52%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCV-CGPGYRPAGRGV-RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
N GSF+C+ C PGYR G G R +ECA P C N GS+ C C GY D
Sbjct: 799 NKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPD 858
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCPSP 359
G +C DVDECE ICSNT GS++C C GY D C DI+EC C
Sbjct: 859 GRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIG- 917
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP---CRNYAGGYRCDCPVG 530
G C+N GS+RC+CP+G+RL G +C D DEC+Q P C+N G Y C C G
Sbjct: 918 GDCINTNGSYRCLCPQGHRL-VGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEG 976
Score = 135 bits (326), Expect = 1e-31
Identities = 77/185 (41%), Positives = 94/185 (50%), Gaps = 11/185 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR----PAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGY 170
+NT GS+ C C GYR GR +ECA +P C C N G Y C C GY
Sbjct: 712 MNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECA-KPHLCGDGGFCINFPGHYKCNCYPGY 770
Query: 171 ELDEDGAN-CRDVDECERDTHTCQQ-ICSNTEGSYEC-SCEDGYEKR-GDACVDINECHE 338
L C D+DEC RD +C C N GS++C +C+ GY + G AC D+NEC E
Sbjct: 771 RLKASRPPVCEDIDEC-RDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAE 829
Query: 339 EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRC 515
C SPG C NL GSFRC C +GY +G C+D DEC C C N G ++C
Sbjct: 830 GSPC-SPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQC 888
Query: 516 DCPVG 530
C G
Sbjct: 889 QCLSG 893
Score = 132 bits (318), Expect = 1e-30
Identities = 74/187 (39%), Positives = 93/187 (49%), Gaps = 12/187 (6%)
Frame = +3
Query: 27 FRCVCGPGYR--PAGRGVRGRDECAVRP-PPCDQLCHNTDGSYDCLCRTGYELD--EDGA 191
+ C C PGYR P R +EC P P +C NT GSY+C C GY L G
Sbjct: 676 YSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGR 735
Query: 192 NCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE---KRGDACVDINECHEEGVCPS 356
+C D++EC + H C C N G Y+C+C GY R C DI+EC + CP
Sbjct: 736 SCVDLNECAKP-HLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPD 794
Query: 357 PGRCVNLLGSFRCV-CPRGYRLDAEGARCVDRDECAQTGRCQAP-CRNYAGGYRCDCPVG 530
G+C N GSF+C+ C GYR GA C D +ECA+ C C N G +RC C G
Sbjct: 795 -GKCENKPGSFKCIACQPGYRSQGGGA-CRDVNECAEGSPCSPGWCENLPGSFRCTCAQG 852
Query: 531 TVRSPSG 551
+P G
Sbjct: 853 YAPAPDG 859
Score = 130 bits (313), Expect = 4e-30
Identities = 73/182 (40%), Positives = 91/182 (50%), Gaps = 8/182 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR-PAGRG--VRGRDECAVRPPPC-DQLCHNTDGSYDCL-CRTGYE 173
+N G ++C C PGYR A R DEC P C D C N GS+ C+ C+ GY
Sbjct: 756 INFPGHYKCNCYPGYRLKASRPPVCEDIDECR-DPSSCPDGKCENKPGSFKCIACQPGYR 814
Query: 174 LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR--GDACVDINECHEEGV 347
GA CRDV+EC + C N GS+ C+C GY G +C+D++EC V
Sbjct: 815 SQGGGA-CRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDV 873
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCP 524
C + G C N GSF+C C GY L + + C D DEC C C N G YRC CP
Sbjct: 874 CDN-GICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCP 932
Query: 525 VG 530
G
Sbjct: 933 QG 934
Score = 122 bits (293), Expect = 1e-27
Identities = 64/178 (35%), Positives = 85/178 (47%), Gaps = 4/178 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
N GSFRC C GY PA GR DEC + +C NT GS+ C C +GY L D
Sbjct: 840 NLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRD 899
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE-KRGDACVDINECHEE-GVCPSP 359
++C D+DEC+ C NT GSY C C G+ G C DI+EC ++ +C
Sbjct: 900 RSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPH 959
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGT 533
G C NL GS+ CVC G+ + C + ++ C N+ CD + T
Sbjct: 960 GACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYL---NFDDTVFCDSVLAT 1014
Score = 104 bits (249), Expect = 2e-22
Identities = 59/164 (35%), Positives = 72/164 (43%), Gaps = 8/164 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDT-HTCQQICSNT 257
DEC + C C Y C C GY C DV+ECE + + IC NT
Sbjct: 655 DECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNT 714
Query: 258 EGSYECSCEDGYEKR----GDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDA 425
GSY C C GY G +CVD+NEC + +C G C+N G ++C C GYRL A
Sbjct: 715 GGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKA 774
Query: 426 EGAR-CVDRDECAQTGRC-QAPCRNYAGGYRCDCPVGTVRSPSG 551
C D DEC C C N G ++C RS G
Sbjct: 775 SRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGG 818
Score = 86.6 bits (205), Expect = 5e-17
Identities = 46/117 (39%), Positives = 57/117 (48%), Gaps = 7/117 (5%)
Frame = +3
Query: 201 DVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCPSPGRCV 371
+ DEC + + C C Y C C GY CVD+NEC E P G C+
Sbjct: 653 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICM 712
Query: 372 NLLGSFRCVCPRGYRL--DAEGARCVDRDECAQTGRC--QAPCRNYAGGYRCDCPVG 530
N GS+ C C RGYRL A G CVD +ECA+ C C N+ G Y+C+C G
Sbjct: 713 NTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPG 769
Score = 84.6 bits (200), Expect = 2e-16
Identities = 39/100 (39%), Positives = 53/100 (53%), Gaps = 7/100 (7%)
Frame = +3
Query: 123 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCED--GYE 296
C NT Y+C C+ G+ D + C DVDEC +++ +C NT G Y C+C Y
Sbjct: 1089 CVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYS 1148
Query: 297 KRGDAC-----VDINECHEEGVCPSPGRCVNLLGSFRCVC 401
C +D++EC + C PGRCVNL GS+RC C
Sbjct: 1149 PAQRQCLSPEEMDVDECQDPAAC-RPGRCVNLPGSYRCEC 1187
Score = 83.0 bits (196), Expect = 6e-16
Identities = 62/190 (32%), Positives = 83/190 (43%), Gaps = 17/190 (8%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTG--YELDEDGANC--- 197
C C G AG G D C + P P + + LC G Y D + N
Sbjct: 1021 CCCSLG---AGWG----DHCEIYPCPV-----YSSAEFHSLCPDGKGYTQDNNIVNYGIP 1068
Query: 198 --RDVDECER-DTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCPSP 359
RD+DEC + C++ C NT+ YEC C+ G+ G+ CVD++EC +E C +
Sbjct: 1069 AHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRN- 1127
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARC-----VDRDECAQTGRCQ-APCRNYAGGYRCDC 521
G C N G +RC C +C +D DEC C+ C N G YRC+C
Sbjct: 1128 GVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQDPAACRPGRCVNLPGSYRCEC 1187
Query: 522 PVGTVRSPSG 551
V PSG
Sbjct: 1188 RPPWVPGPSG 1197
Score = 73.3 bits (172), Expect = 5e-13
Identities = 68/207 (32%), Positives = 90/207 (43%), Gaps = 24/207 (11%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSY---------- 146
R VN GS+RC C P + P+GR + + A R P +C + G
Sbjct: 1175 RCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQRGEDGMCAGPLAGP 1234
Query: 147 -----DCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECS-CEDGYEKRGD 308
DC CR G GA CR +H C S + ++ S G R +
Sbjct: 1235 ALTFDDCCCRQGRGW---GAQCRPCPPRGAGSH-CPTSQSESNSFWDTSPLLLGKPPRDE 1290
Query: 309 ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR----C 476
+ E +E C S GRCV G C CP G++LDA ARCVD DEC + + C
Sbjct: 1291 DSSE--EDSDECRCVS-GRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLC 1347
Query: 477 QAP-CRNYAGGYRCDCPVGTVRS-PSG 551
++ C N +G +RC C G RS P G
Sbjct: 1348 KSERCVNTSGSFRCVCKAGFARSRPHG 1374
Score = 67.7 bits (158), Expect = 3e-11
Identities = 58/194 (29%), Positives = 80/194 (41%), Gaps = 15/194 (7%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCH-NTDGSYDCLCRTGYELDEDG 188
N GS+ CVC G+ P + G +E V P + C+ N D + C + +
Sbjct: 964 NLQGSYVCVCDEGFTPT-QDQHGCEE--VEQPHHKKECYLNFDDTVFCDSVLATNVTQQE 1020
Query: 189 ANCRDV----DECERDTHTCQQICSNTEGSYECSCEDGYEKRGD-------ACVDINECH 335
C D CE + C + S+ E C GY + + A DI+EC
Sbjct: 1021 CCCSLGAGWGDHCE--IYPCP-VYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECM 1077
Query: 336 EEG--VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ-APCRNYAGG 506
G +C G+CVN + C C +G+ D CVD DEC C+ C N GG
Sbjct: 1078 LFGSEICKE-GKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGG 1136
Query: 507 YRCDCPVGTVRSPS 548
YRC C SP+
Sbjct: 1137 YRCACTPPAEYSPA 1150
Score = 67.3 bits (157), Expect = 3e-11
Identities = 58/189 (30%), Positives = 76/189 (40%), Gaps = 15/189 (7%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR-PAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELD 179
+NT GS+RC+C G+R GR + DEC+ P C C N GSY C+C G+
Sbjct: 921 INTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPT 980
Query: 180 EDGANCRDVD------ECE---RDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINEC 332
+D C +V+ EC DT C + + EC C G GD C +I C
Sbjct: 981 QDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLG-AGWGDHC-EIYPC 1038
Query: 333 HEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR--C-QAPCRNYAG 503
C + G + Y + A D DEC G C + C N
Sbjct: 1039 PVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHR----DIDECMLFGSEICKEGKCVNTQP 1094
Query: 504 GYRCDCPVG 530
GY C C G
Sbjct: 1095 GYECYCKQG 1103
Score = 60.1 bits (139), Expect = 5e-09
Identities = 39/117 (33%), Positives = 52/117 (44%), Gaps = 10/117 (8%)
Frame = +3
Query: 210 ECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CVDINECHEEGVCPSPGRCVNLLGS 386
+C + +T Q G C GY++ C DINEC GVC G C+N GS
Sbjct: 397 KCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECAMPGVCRH-GDCLNNPGS 455
Query: 387 FRCVCPRGYRLDAEGARCV-DRDE----C----AQTGRCQAPCRNYAGGYRCDCPVG 530
+RCVCP G+ L +C+ D+ E C + +CQ P C C VG
Sbjct: 456 YRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVG 512
Score = 59.3 bits (137), Expect = 9e-09
Identities = 33/90 (36%), Positives = 41/90 (45%), Gaps = 8/90 (8%)
Frame = +3
Query: 198 RDVDECERDTHTCQQI---CSNTEGSYECSCEDGYEKRGDA--CVDINECHE---EGVCP 353
RD D E D+ C+ + C G C C G++ CVDI+EC E G+
Sbjct: 1288 RDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLC 1347
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCV 443
RCVN GSFRCVC G+ CV
Sbjct: 1348 KSERCVNTSGSFRCVCKAGFARSRPHGACV 1377
Score = 50.0 bits (114), Expect = 5e-06
Identities = 33/99 (33%), Positives = 40/99 (40%), Gaps = 8/99 (8%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VNT + C C G+ G + DEC + +C NT G Y C C E
Sbjct: 1090 VNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSP 1149
Query: 183 DGANC-----RDVDECERDTHTCQQ-ICSNTEGSYECSC 281
C DVDEC+ D C+ C N GSY C C
Sbjct: 1150 AQRQCLSPEEMDVDECQ-DPAACRPGRCVNLPGSYRCEC 1187
Score = 46.8 bits (106), Expect = 5e-05
Identities = 22/51 (43%), Positives = 26/51 (50%), Gaps = 1/51 (1%)
Frame = +3
Query: 399 CPRGYRLDAEGARCVDRDECAQTGRCQ-APCRNYAGGYRCDCPVGTVRSPS 548
CP+GY+ C D +ECA G C+ C N G YRC CP G PS
Sbjct: 420 CPQGYKR-LNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPS 469
Score = 33.1 bits (72), Expect = 0.67
Identities = 37/136 (27%), Positives = 53/136 (38%), Gaps = 12/136 (8%)
Frame = +3
Query: 39 CGPGY-RPAGRGVRGRDECAVRPPPCDQL-CHNTDGSYDCLCRTGYELDEDGANC-RDVD 209
C GY R + +ECA+ P C C N GSY C+C G+ L C D
Sbjct: 420 CPQGYKRLNSTHCQDINECAM-PGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKP 478
Query: 210 E----CER---DTHTCQQICSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCPSPG 362
E C R H CQ + C C G + R C + +CP+ G
Sbjct: 479 EEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKEICPA-G 537
Query: 363 RCVNLLGSFRCVCPRG 410
+ ++L S + + +G
Sbjct: 538 KGYHILTSHQTLTIQG 553
>AF135960-1|AAF62352.3| 1256|Homo sapiens latent transforming growth
factor beta binding protein 3 protein.
Length = 1256
Score = 151 bits (365), Expect = 2e-36
Identities = 79/180 (43%), Positives = 95/180 (52%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCV-CGPGYRPAGRGV-RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
N GSF+C+ C PGYR G G R +ECA P C N GS+ C C GY D
Sbjct: 720 NKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPD 779
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCPSP 359
G +C DVDECE ICSNT GS++C C GY D C DI+EC C
Sbjct: 780 GRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIG- 838
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP---CRNYAGGYRCDCPVG 530
G C+N GS+RC+CP+G+RL G +C D DEC+Q P C+N G Y C C G
Sbjct: 839 GDCINTNGSYRCLCPQGHRL-VGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEG 897
Score = 135 bits (326), Expect = 1e-31
Identities = 77/185 (41%), Positives = 94/185 (50%), Gaps = 11/185 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR----PAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGY 170
+NT GS+ C C GYR GR +ECA +P C C N G Y C C GY
Sbjct: 633 MNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECA-KPHLCGDGGFCINFPGHYKCNCYPGY 691
Query: 171 ELDEDGAN-CRDVDECERDTHTCQQ-ICSNTEGSYEC-SCEDGYEKR-GDACVDINECHE 338
L C D+DEC RD +C C N GS++C +C+ GY + G AC D+NEC E
Sbjct: 692 RLKASRPPVCEDIDEC-RDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAE 750
Query: 339 EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRC 515
C SPG C NL GSFRC C +GY +G C+D DEC C C N G ++C
Sbjct: 751 GSPC-SPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQC 809
Query: 516 DCPVG 530
C G
Sbjct: 810 QCLSG 814
Score = 132 bits (318), Expect = 1e-30
Identities = 74/187 (39%), Positives = 93/187 (49%), Gaps = 12/187 (6%)
Frame = +3
Query: 27 FRCVCGPGYR--PAGRGVRGRDECAVRP-PPCDQLCHNTDGSYDCLCRTGYELD--EDGA 191
+ C C PGYR P R +EC P P +C NT GSY+C C GY L G
Sbjct: 597 YSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGR 656
Query: 192 NCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYE---KRGDACVDINECHEEGVCPS 356
+C D++EC + H C C N G Y+C+C GY R C DI+EC + CP
Sbjct: 657 SCVDLNECAKP-HLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPD 715
Query: 357 PGRCVNLLGSFRCV-CPRGYRLDAEGARCVDRDECAQTGRCQAP-CRNYAGGYRCDCPVG 530
G+C N GSF+C+ C GYR GA C D +ECA+ C C N G +RC C G
Sbjct: 716 -GKCENKPGSFKCIACQPGYRSQGGGA-CRDVNECAEGSPCSPGWCENLPGSFRCTCAQG 773
Query: 531 TVRSPSG 551
+P G
Sbjct: 774 YAPAPDG 780
Score = 130 bits (313), Expect = 4e-30
Identities = 73/182 (40%), Positives = 91/182 (50%), Gaps = 8/182 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR-PAGRG--VRGRDECAVRPPPC-DQLCHNTDGSYDCL-CRTGYE 173
+N G ++C C PGYR A R DEC P C D C N GS+ C+ C+ GY
Sbjct: 677 INFPGHYKCNCYPGYRLKASRPPVCEDIDECR-DPSSCPDGKCENKPGSFKCIACQPGYR 735
Query: 174 LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR--GDACVDINECHEEGV 347
GA CRDV+EC + C N GS+ C+C GY G +C+D++EC V
Sbjct: 736 SQGGGA-CRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDV 794
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCP 524
C + G C N GSF+C C GY L + + C D DEC C C N G YRC CP
Sbjct: 795 CDN-GICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCP 853
Query: 525 VG 530
G
Sbjct: 854 QG 855
Score = 122 bits (293), Expect = 1e-27
Identities = 64/178 (35%), Positives = 85/178 (47%), Gaps = 4/178 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
N GSFRC C GY PA GR DEC + +C NT GS+ C C +GY L D
Sbjct: 761 NLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRD 820
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE-KRGDACVDINECHEE-GVCPSP 359
++C D+DEC+ C NT GSY C C G+ G C DI+EC ++ +C
Sbjct: 821 RSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPH 880
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGT 533
G C NL GS+ CVC G+ + C + ++ C N+ CD + T
Sbjct: 881 GACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYL---NFDDTVFCDSVLAT 935
Score = 104 bits (249), Expect = 2e-22
Identities = 59/164 (35%), Positives = 72/164 (43%), Gaps = 8/164 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDT-HTCQQICSNT 257
DEC + C C Y C C GY C DV+ECE + + IC NT
Sbjct: 576 DECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNT 635
Query: 258 EGSYECSCEDGYEKR----GDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDA 425
GSY C C GY G +CVD+NEC + +C G C+N G ++C C GYRL A
Sbjct: 636 GGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKA 695
Query: 426 EGAR-CVDRDECAQTGRC-QAPCRNYAGGYRCDCPVGTVRSPSG 551
C D DEC C C N G ++C RS G
Sbjct: 696 SRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGG 739
Score = 86.6 bits (205), Expect = 5e-17
Identities = 46/117 (39%), Positives = 57/117 (48%), Gaps = 7/117 (5%)
Frame = +3
Query: 201 DVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCPSPGRCV 371
+ DEC + + C C Y C C GY CVD+NEC E P G C+
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICM 633
Query: 372 NLLGSFRCVCPRGYRL--DAEGARCVDRDECAQTGRC--QAPCRNYAGGYRCDCPVG 530
N GS+ C C RGYRL A G CVD +ECA+ C C N+ G Y+C+C G
Sbjct: 634 NTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPG 690
Score = 70.1 bits (164), Expect = 5e-12
Identities = 67/204 (32%), Positives = 86/204 (42%), Gaps = 24/204 (11%)
Frame = +3
Query: 12 NTIGSFRCVCGPG--YRPAGRGVRGRDECAVRPPPCDQLCHNTDGSY------------- 146
NT G +RC C P Y PA R +E R P +C + G
Sbjct: 1053 NTRGGYRCACTPPAEYSPAQRQCLSPEEME-RAPERRDVCWSQRGEDGMCAGPLAGPALT 1111
Query: 147 --DCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECS-CEDGYEKRGDACV 317
DC CR G GA CR +H C S + ++ S G R +
Sbjct: 1112 FDDCCCRQGRGW---GAQCRPCPPRGAGSH-CPTSQSESNSFWDTSPLLLGKPPRDEDSS 1167
Query: 318 DINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR----CQAP 485
+ E +E C S GRCV G C CP G++LDA ARCVD DEC + + C++
Sbjct: 1168 E--EDSDECRCVS-GRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSE 1224
Query: 486 -CRNYAGGYRCDCPVGTVRS-PSG 551
C N +G +RC C G RS P G
Sbjct: 1225 RCVNTSGSFRCVCKAGFARSRPHG 1248
Score = 67.7 bits (158), Expect = 3e-11
Identities = 58/194 (29%), Positives = 80/194 (41%), Gaps = 15/194 (7%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCH-NTDGSYDCLCRTGYELDEDG 188
N GS+ CVC G+ P + G +E V P + C+ N D + C + +
Sbjct: 885 NLQGSYVCVCDEGFTPT-QDQHGCEE--VEQPHHKKECYLNFDDTVFCDSVLATNVTQQE 941
Query: 189 ANCRDV----DECERDTHTCQQICSNTEGSYECSCEDGYEKRGD-------ACVDINECH 335
C D CE + C + S+ E C GY + + A DI+EC
Sbjct: 942 CCCSLGAGWGDHCE--IYPCP-VYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECM 998
Query: 336 EEG--VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ-APCRNYAGG 506
G +C G+CVN + C C +G+ D CVD DEC C+ C N GG
Sbjct: 999 LFGSEICKE-GKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGG 1057
Query: 507 YRCDCPVGTVRSPS 548
YRC C SP+
Sbjct: 1058 YRCACTPPAEYSPA 1071
Score = 67.3 bits (157), Expect = 3e-11
Identities = 58/189 (30%), Positives = 76/189 (40%), Gaps = 15/189 (7%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR-PAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELD 179
+NT GS+RC+C G+R GR + DEC+ P C C N GSY C+C G+
Sbjct: 842 INTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPT 901
Query: 180 EDGANCRDVD------ECE---RDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINEC 332
+D C +V+ EC DT C + + EC C G GD C +I C
Sbjct: 902 QDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLG-AGWGDHC-EIYPC 959
Query: 333 HEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR--C-QAPCRNYAG 503
C + G + Y + A D DEC G C + C N
Sbjct: 960 PVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHR----DIDECMLFGSEICKEGKCVNTQP 1015
Query: 504 GYRCDCPVG 530
GY C C G
Sbjct: 1016 GYECYCKQG 1024
Score = 62.9 bits (146), Expect = 7e-10
Identities = 49/168 (29%), Positives = 72/168 (42%), Gaps = 11/168 (6%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTG--YELDEDGANC--- 197
C C G AG G D C + P P + + LC G Y D + N
Sbjct: 942 CCCSLG---AGWG----DHCEIYPCPV-----YSSAEFHSLCPDGKGYTQDNNIVNYGIP 989
Query: 198 --RDVDECER-DTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCPSP 359
RD+DEC + C++ C NT+ YEC C+ G+ G+ CVD++EC +E C +
Sbjct: 990 AHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRN- 1048
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAG 503
G C N G +RC C +C+ +E + + C + G
Sbjct: 1049 GVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPERRDVCWSQRG 1096
Score = 60.1 bits (139), Expect = 5e-09
Identities = 39/117 (33%), Positives = 52/117 (44%), Gaps = 10/117 (8%)
Frame = +3
Query: 210 ECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CVDINECHEEGVCPSPGRCVNLLGS 386
+C + +T Q G C GY++ C DINEC GVC G C+N GS
Sbjct: 318 KCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECAMPGVCRH-GDCLNNPGS 376
Query: 387 FRCVCPRGYRLDAEGARCV-DRDE----C----AQTGRCQAPCRNYAGGYRCDCPVG 530
+RCVCP G+ L +C+ D+ E C + +CQ P C C VG
Sbjct: 377 YRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVG 433
Score = 59.3 bits (137), Expect = 9e-09
Identities = 33/90 (36%), Positives = 41/90 (45%), Gaps = 8/90 (8%)
Frame = +3
Query: 198 RDVDECERDTHTCQQI---CSNTEGSYECSCEDGYEKRGDA--CVDINECHE---EGVCP 353
RD D E D+ C+ + C G C C G++ CVDI+EC E G+
Sbjct: 1162 RDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLC 1221
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCV 443
RCVN GSFRCVC G+ CV
Sbjct: 1222 KSERCVNTSGSFRCVCKAGFARSRPHGACV 1251
Score = 46.8 bits (106), Expect = 5e-05
Identities = 22/51 (43%), Positives = 26/51 (50%), Gaps = 1/51 (1%)
Frame = +3
Query: 399 CPRGYRLDAEGARCVDRDECAQTGRCQ-APCRNYAGGYRCDCPVGTVRSPS 548
CP+GY+ C D +ECA G C+ C N G YRC CP G PS
Sbjct: 341 CPQGYKR-LNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPS 390
Score = 37.1 bits (82), Expect = 0.041
Identities = 24/87 (27%), Positives = 33/87 (37%), Gaps = 2/87 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VNT + C C G+ G + DEC + +C NT G Y C C E
Sbjct: 1011 VNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSP 1070
Query: 183 DGANCRDVDECERDTHTCQQICSNTEG 263
C +E ER + +C + G
Sbjct: 1071 AQRQCLSPEEMERAPER-RDVCWSQRG 1096
Score = 33.1 bits (72), Expect = 0.67
Identities = 37/136 (27%), Positives = 53/136 (38%), Gaps = 12/136 (8%)
Frame = +3
Query: 39 CGPGY-RPAGRGVRGRDECAVRPPPCDQL-CHNTDGSYDCLCRTGYELDEDGANC-RDVD 209
C GY R + +ECA+ P C C N GSY C+C G+ L C D
Sbjct: 341 CPQGYKRLNSTHCQDINECAM-PGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKP 399
Query: 210 E----CER---DTHTCQQICSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCPSPG 362
E C R H CQ + C C G + R C + +CP+ G
Sbjct: 400 EEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKEICPA-G 458
Query: 363 RCVNLLGSFRCVCPRG 410
+ ++L S + + +G
Sbjct: 459 KGYHILTSHQTLTIQG 474
Score = 30.7 bits (66), Expect = 3.6
Identities = 17/30 (56%), Positives = 18/30 (60%), Gaps = 3/30 (10%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGY---RPAGRGVRGR 83
R VNT GSFRCVC G+ RP G V R
Sbjct: 1225 RCVNTSGSFRCVCKAGFARSRPHGACVPQR 1254
>X62009-1|CAB56757.1| 754|Homo sapiens fibrillin 5 protein.
Length = 754
Score = 149 bits (360), Expect = 8e-36
Identities = 73/185 (39%), Positives = 94/185 (50%), Gaps = 9/185 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN IG+++C C PGY+ P +G DEC + CD C N++GSY+C C GY L
Sbjct: 465 VNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMP 524
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECH-EEGVC 350
DG +C D+DECE + C C+N G Y C C DG+ D C+D+NEC +C
Sbjct: 525 DGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNIC 584
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC---AQTGRCQAPCRNYAGGYRCDC 521
G C N GSF C C GY + C D DEC A A C N G ++C C
Sbjct: 585 MF-GECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSC 643
Query: 522 PVGTV 536
G +
Sbjct: 644 REGWI 648
Score = 148 bits (359), Expect = 1e-35
Identities = 78/190 (41%), Positives = 101/190 (53%), Gaps = 10/190 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELD- 179
NTIGSF+C C G+ R DEC + P C +C NT GS++C C GYE
Sbjct: 339 NTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGF 398
Query: 180 EDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYE---KRGDACVDINECH-EEG 344
NC D+D CER+ C+ C NTEGS++C C G+E R D CVDINEC +
Sbjct: 399 MMMKNCMDIDGCERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSRED-CVDINECSLSDN 457
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRCDC 521
+C + G+CVN++G+++C C GY+ + C D DEC G C C N G Y C C
Sbjct: 458 LCRN-GKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSC 516
Query: 522 PVGTVRSPSG 551
G P G
Sbjct: 517 SEGYALMPDG 526
Score = 131 bits (316), Expect = 2e-30
Identities = 65/181 (35%), Positives = 91/181 (50%), Gaps = 7/181 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELD 179
VNT GSF+C C G+ P+ +EC++ C + C N G+Y C C GY+
Sbjct: 423 VNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQAT 482
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCP 353
D C D+DEC C C+N+EGSYECSC +GY G +C DI+EC
Sbjct: 483 PDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDIC 542
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQ-APCRNYAGGYRCDCPV 527
G+C N+ G +RC+C G+ + C+D +EC + C C N G + C C +
Sbjct: 543 DGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQL 602
Query: 528 G 530
G
Sbjct: 603 G 603
Score = 128 bits (308), Expect = 2e-29
Identities = 66/181 (36%), Positives = 92/181 (50%), Gaps = 8/181 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPPCD-QLCHNTDGSYDCLCRTGYELDE 182
N G +RC+C G+ + + +EC + C C NT GS+ C C+ GY + +
Sbjct: 549 NIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKK 608
Query: 183 DGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACVDINEC-HEEGVCP 353
C DVDECE H C C N GS++CSC +G+ G C+D +EC + C
Sbjct: 609 GTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDRDECSNGTHQCS 668
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQT-GRCQ-APCRNYAGGYRCDCPV 527
+CVN GS+RC C G+ +G C D DECA+ C+ C N G YRC+C +
Sbjct: 669 INAQCVNTPGSYRCACSEGF--TGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEM 726
Query: 528 G 530
G
Sbjct: 727 G 727
Score = 126 bits (304), Expect = 5e-29
Identities = 69/184 (37%), Positives = 90/184 (48%), Gaps = 13/184 (7%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGR------DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGA 191
C G G+ G + GR +EC P C C NT GS+ C C +G+ LD +
Sbjct: 300 CPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEER 359
Query: 192 NCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEK---RGDACVDINECHEEGVCPSP 359
NC D+DEC C IC NT GS+EC C +GYE C+DI+ C +
Sbjct: 360 NCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDGCERNPLLCRG 419
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQ-APCRNYAGGYRCDCPVGT 533
G CVN GSF+C CP G+ L CVD +EC+ + C+ C N G Y+C C G
Sbjct: 420 GTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGY 479
Query: 534 VRSP 545
+P
Sbjct: 480 QATP 483
Score = 123 bits (296), Expect = 5e-28
Identities = 71/188 (37%), Positives = 89/188 (47%), Gaps = 10/188 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA---GRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYEL 176
VNT GSF C C GY + D C P C C NT+GS+ C C G+EL
Sbjct: 380 VNTPGSFECECFEGYESGFMMMKNCMDIDGCERNPLLCRGGTCVNTEGSFQCDCPLGHEL 439
Query: 177 DEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECH-EEG 344
+C D++EC + C+ C N G+Y+CSC GY+ D C DI+EC G
Sbjct: 440 SPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNG 499
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQT-GRCQ-APCRNYAGGYRCD 518
C + +C N GS+ C C GY L +G C D DEC C C N G YRC
Sbjct: 500 GCDT--QCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCL 557
Query: 519 CPVGTVRS 542
C G + S
Sbjct: 558 CYDGFMAS 565
Score = 117 bits (282), Expect = 2e-26
Identities = 62/142 (43%), Positives = 77/142 (54%), Gaps = 4/142 (2%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C G G GR + +ECA+ P C + +C N GSY C C +GYE D G NC D+D
Sbjct: 4 CSSGVGITVDGRDI---NECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDID 60
Query: 210 ECERDTHTCQQ-ICSNTEGSYECSCEDGYEKR--GDACVDINECHEEGVCPSPGRCVNLL 380
EC + C +C NT GSY C+C GY R + C DINEC E C + G C N L
Sbjct: 61 ECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINEC-ESNPCVN-GACRNNL 118
Query: 381 GSFRCVCPRGYRLDAEGARCVD 446
GSF C C G +L + G C+D
Sbjct: 119 GSFNCECSPGSKLSSTGLICID 140
Score = 109 bits (261), Expect = 8e-24
Identities = 57/150 (38%), Positives = 77/150 (51%), Gaps = 7/150 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELD 179
NT GSF C C GY + G DEC + CD C N GS+ C CR G+
Sbjct: 591 NTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWI-- 648
Query: 180 EDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRGDACVDINECHEE-GVC 350
+G C D DEC TH C C NT GSY C+C +G+ G C D++EC E +C
Sbjct: 649 GNGIKCIDRDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAENINLC 708
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARC 440
+ G+C+N+ G++RC C G+ ++ C
Sbjct: 709 EN-GQCLNVPGAYRCECEMGFTPASDSRSC 737
Score = 105 bits (251), Expect = 1e-22
Identities = 52/136 (38%), Positives = 66/136 (48%), Gaps = 3/136 (2%)
Frame = +3
Query: 153 LCRTGYELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEK--RGDACVDI 323
LC +G + DG RD++EC D C IC N GSY C+C GYE G C+DI
Sbjct: 3 LCSSGVGITVDG---RDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDI 59
Query: 324 NECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAG 503
+EC + G C N GS+ C CP GY E C D +EC CRN G
Sbjct: 60 DECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGACRNNLG 119
Query: 504 GYRCDCPVGTVRSPSG 551
+ C+C G+ S +G
Sbjct: 120 SFNCECSPGSKLSSTG 135
Score = 94.7 bits (225), Expect = 2e-19
Identities = 69/209 (33%), Positives = 86/209 (41%), Gaps = 29/209 (13%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRP--AGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
N GS+RC C GY P +GR DEC V CD LC NT GSY C C GY
Sbjct: 34 NLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRT 93
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG--YEKRGDACVD-------IN--- 326
+ C D++ECE + C N GS+ C C G G C+D +N
Sbjct: 94 ETETCEDINECESNP-CVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQD 152
Query: 327 ---ECHEEGVCPSPGRCVNLLGSF-----RC----VCPRGYRLDAEGARCVDRDEC-AQT 467
E + G C L ++ RC CPRG +G C D +EC
Sbjct: 153 SRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGL-ARIKGVTCEDVNECEVFP 211
Query: 468 GRC-QAPCRNYAGGYRCDCPVGTVRSPSG 551
G C C N G + C+CP G +G
Sbjct: 212 GVCPNGRCVNSKGSFHCECPEGLTLDGTG 240
Score = 82.2 bits (194), Expect = 1e-15
Identities = 59/172 (34%), Positives = 76/172 (44%), Gaps = 27/172 (15%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT GS+ C C PGY R +EC P + C N GS++C C G +L
Sbjct: 76 NTPGSYSCTCPPGYVFRTETETCEDINECESNPC-VNGACRNNLGSFNCECSPGSKLSST 134
Query: 186 GANCRDV-----------DECERDTH--TCQQICSNTEGS----------YECSCEDGYE 296
G C D CE + + T + C T G+ + +C G
Sbjct: 135 GLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLA 194
Query: 297 K-RGDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
+ +G C D+NEC GVCP+ GRCVN GSF C CP G LD G C+D
Sbjct: 195 RIKGVTCEDVNECEVFPGVCPN-GRCVNSKGSFHCECPEGLTLDGTGRVCLD 245
Score = 79.0 bits (186), Expect = 1e-14
Identities = 46/124 (37%), Positives = 63/124 (50%), Gaps = 7/124 (5%)
Frame = +3
Query: 198 RDVDECERDTHTCQQ-ICSNTEGSYECSCEDGY--EKRGDACVDINECH-EEGVCPSPGR 365
+D++EC+ C C NT GS++C C G+ + C DI+EC +C S G
Sbjct: 320 KDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGS-GI 378
Query: 366 CVNLLGSFRCVCPRGYRLDAEGAR-CVDRDECAQTGR-CQA-PCRNYAGGYRCDCPVGTV 536
CVN GSF C C GY + C+D D C + C+ C N G ++CDCP+G
Sbjct: 379 CVNTPGSFECECFEGYESGFMMMKNCMDIDGCERNPLLCRGGTCVNTEGSFQCDCPLGHE 438
Query: 537 RSPS 548
SPS
Sbjct: 439 LSPS 442
Score = 78.2 bits (184), Expect = 2e-14
Identities = 40/104 (38%), Positives = 52/104 (50%), Gaps = 3/104 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDE 182
+N GSF+C C G+ G RDEC+ C + C NT GSY C C G+
Sbjct: 633 LNIPGSFKCSCREGWIGNGIKCIDRDECSNGTHQCSINAQCVNTPGSYRCACSEGF--TG 690
Query: 183 DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA 311
DG C DVDEC + + C+ C N G+Y C CE G+ D+
Sbjct: 691 DGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDS 734
Score = 69.3 bits (162), Expect = 8e-12
Identities = 57/187 (30%), Positives = 76/187 (40%), Gaps = 41/187 (21%)
Frame = +3
Query: 84 DECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDV--DEC--ERDTHTC---- 236
+EC V P C C N+ GS+ C C G LD G C D+ ++C + D C
Sbjct: 205 NECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPV 264
Query: 237 ------QQICSNTEGSYECSCED-----------------GYEKRGDACV------DINE 329
C ++ CE+ G+ RGD DINE
Sbjct: 265 PGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINE 324
Query: 330 CHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC-QAPCRNYA 500
C G+C + G+C N +GSF+C C G+ LD E C D DEC C C N
Sbjct: 325 CKAFPGMC-TYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTP 383
Query: 501 GGYRCDC 521
G + C+C
Sbjct: 384 GSFECEC 390
Score = 50.0 bits (114), Expect = 5e-06
Identities = 24/65 (36%), Positives = 31/65 (47%), Gaps = 1/65 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDED 185
VNT GS+RC C G+ G DECA C+ C N G+Y C C G+ D
Sbjct: 674 VNTPGSYRCACSEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASD 733
Query: 186 GANCR 200
+C+
Sbjct: 734 SRSCQ 738
Score = 48.0 bits (109), Expect = 2e-05
Identities = 60/236 (25%), Positives = 89/236 (37%), Gaps = 63/236 (26%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGV------RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGY- 170
N +GSF C C PG + + G+ +G ++ C+ + +C G
Sbjct: 116 NNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAA 175
Query: 171 --------ELDE---------DGANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDG-- 290
ELD G C DV+ECE C C N++GS+ C C +G
Sbjct: 176 WGSPCERCELDTACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLT 235
Query: 291 YEKRGDACVDI--NECH-----EEGVCPSPGR-----CVNLLGS---------------- 386
+ G C+DI +C+ +E + P PG+ C +G+
Sbjct: 236 LDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKE 295
Query: 387 FRCVCPRGYRLDAEGARCVDR------DEC-AQTGRC-QAPCRNYAGGYRCDCPVG 530
+ +CPRG G R +EC A G C CRN G ++C C G
Sbjct: 296 YETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSG 351
>BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone RP11-465I11 on chromosome 1 Contains part of
the gene for hemicentin (FIBL-6). ).
Length = 5635
Score = 147 bits (355), Expect = 3e-35
Identities = 77/182 (42%), Positives = 97/182 (53%), Gaps = 9/182 (4%)
Frame = +3
Query: 12 NTIGSFRCV--CGPGYRPAGRGVRGRD--ECAVRPPPCDQLCHNTDGSYDCLCRTGYELD 179
NTIGS+RCV CG G+R G+ +D EC PC Q C N GS+ C C GY+L
Sbjct: 5166 NTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQRCFNAIGSFHCGCEPGYQLK 5224
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECS--CEDGYEK-RGDACVDINECHE-EGV 347
G C DV+EC ++ Q C NT G Y+C C +G K C+DI+EC +
Sbjct: 5225 --GRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQ 5282
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQAPCRNYAGGYRCDCP 524
C C N GS+RCVCPRGYR G C+D +EC Q + C C N G ++C CP
Sbjct: 5283 CRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICP 5342
Query: 525 VG 530
G
Sbjct: 5343 PG 5344
Score = 138 bits (335), Expect = 9e-33
Identities = 75/185 (40%), Positives = 94/185 (50%), Gaps = 9/185 (4%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRD 203
S +C G G DECA P C CHN G+Y C C G + DG C+D
Sbjct: 5089 SNQCPSGFTLDSVGPFCADEDECAAGNP-CSHSCHNAMGTYYCSCPKGLTIAADGRTCQD 5147
Query: 204 VDECERDTHTCQ--QICSNTEGSYEC--SCEDGYEKRGD--ACVDINECHEEGVCPSPGR 365
+DEC HTC Q C NT GSY C C G+ + D +C DINEC E C R
Sbjct: 5148 IDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQ--R 5205
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGRCQAPCRNYAGGYRCD--CPVGTV 536
C N +GSF C C GY+L +G +C+D +EC Q R C+N GGY+C CP G
Sbjct: 5206 CFNAIGSFHCGCEPGYQL--KGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMT 5263
Query: 537 RSPSG 551
++ +G
Sbjct: 5264 KAENG 5268
Score = 132 bits (318), Expect = 1e-30
Identities = 70/162 (43%), Positives = 84/162 (51%), Gaps = 6/162 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDC--LCRTGYEL 176
R N IGSF C C PGY+ GR +EC DQ C NT G Y C LC G
Sbjct: 5205 RCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTK 5264
Query: 177 DEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKR--GDACVDINECHEEG 344
E+G C D+DEC+ TH C+ QIC NT GSY C C GY + G C+DINEC E+
Sbjct: 5265 AENG-TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINEC-EQV 5322
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG 470
P +C N GSF+C+CP G L +G C + G
Sbjct: 5323 PKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYG 5364
Score = 85.0 bits (201), Expect = 2e-16
Identities = 57/186 (30%), Positives = 76/186 (40%), Gaps = 8/186 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECA--VRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT GSF+C+C PG G G CA R P + + + R Y+ +
Sbjct: 5332 NTPGSFKCICPPGQHLLGDG----KSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQH 5387
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGR 365
+ + + S T + +C +G E D CVDI+EC C
Sbjct: 5388 YRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQH--E 5445
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC--QAPCRNYAGGYRC---DCPV 527
C N GS++C+CP GY+L G C D DEC Q C C N G Y+C CP
Sbjct: 5446 CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPP 5505
Query: 528 GTVRSP 545
R P
Sbjct: 5506 NYQRDP 5511
Score = 47.6 bits (108), Expect = 3e-05
Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 7/69 (10%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPC--DQLCHNTDGSYDCL---CRTGY 170
NT GS++C+C PGY+ G+ + DEC + C +++C N GSY C+ C Y
Sbjct: 5448 NTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNY 5507
Query: 171 ELDEDGANC 197
+ D C
Sbjct: 5508 QRDPVSGFC 5516
>AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-268N14 on chromosome 1 Contains part of
the gene for hemicentin. ).
Length = 5635
Score = 147 bits (355), Expect = 3e-35
Identities = 77/182 (42%), Positives = 97/182 (53%), Gaps = 9/182 (4%)
Frame = +3
Query: 12 NTIGSFRCV--CGPGYRPAGRGVRGRD--ECAVRPPPCDQLCHNTDGSYDCLCRTGYELD 179
NTIGS+RCV CG G+R G+ +D EC PC Q C N GS+ C C GY+L
Sbjct: 5166 NTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQRCFNAIGSFHCGCEPGYQLK 5224
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECS--CEDGYEK-RGDACVDINECHE-EGV 347
G C DV+EC ++ Q C NT G Y+C C +G K C+DI+EC +
Sbjct: 5225 --GRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQ 5282
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQAPCRNYAGGYRCDCP 524
C C N GS+RCVCPRGYR G C+D +EC Q + C C N G ++C CP
Sbjct: 5283 CRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICP 5342
Query: 525 VG 530
G
Sbjct: 5343 PG 5344
Score = 138 bits (335), Expect = 9e-33
Identities = 75/185 (40%), Positives = 94/185 (50%), Gaps = 9/185 (4%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRD 203
S +C G G DECA P C CHN G+Y C C G + DG C+D
Sbjct: 5089 SNQCPSGFTLDSVGPFCADEDECAAGNP-CSHSCHNAMGTYYCSCPKGLTIAADGRTCQD 5147
Query: 204 VDECERDTHTCQ--QICSNTEGSYEC--SCEDGYEKRGD--ACVDINECHEEGVCPSPGR 365
+DEC HTC Q C NT GSY C C G+ + D +C DINEC E C R
Sbjct: 5148 IDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQ--R 5205
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGRCQAPCRNYAGGYRCD--CPVGTV 536
C N +GSF C C GY+L +G +C+D +EC Q R C+N GGY+C CP G
Sbjct: 5206 CFNAIGSFHCGCEPGYQL--KGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMT 5263
Query: 537 RSPSG 551
++ +G
Sbjct: 5264 KAENG 5268
Score = 132 bits (318), Expect = 1e-30
Identities = 70/162 (43%), Positives = 84/162 (51%), Gaps = 6/162 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDC--LCRTGYEL 176
R N IGSF C C PGY+ GR +EC DQ C NT G Y C LC G
Sbjct: 5205 RCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTK 5264
Query: 177 DEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKR--GDACVDINECHEEG 344
E+G C D+DEC+ TH C+ QIC NT GSY C C GY + G C+DINEC E+
Sbjct: 5265 AENG-TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINEC-EQV 5322
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG 470
P +C N GSF+C+CP G L +G C + G
Sbjct: 5323 PKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYG 5364
Score = 85.0 bits (201), Expect = 2e-16
Identities = 57/186 (30%), Positives = 76/186 (40%), Gaps = 8/186 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECA--VRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT GSF+C+C PG G G CA R P + + + R Y+ +
Sbjct: 5332 NTPGSFKCICPPGQHLLGDG----KSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQH 5387
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGR 365
+ + + S T + +C +G E D CVDI+EC C
Sbjct: 5388 YRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQH--E 5445
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC--QAPCRNYAGGYRC---DCPV 527
C N GS++C+CP GY+L G C D DEC Q C C N G Y+C CP
Sbjct: 5446 CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPP 5505
Query: 528 GTVRSP 545
R P
Sbjct: 5506 NYQRDP 5511
Score = 47.6 bits (108), Expect = 3e-05
Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 7/69 (10%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPC--DQLCHNTDGSYDCL---CRTGY 170
NT GS++C+C PGY+ G+ + DEC + C +++C N GSY C+ C Y
Sbjct: 5448 NTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNY 5507
Query: 171 ELDEDGANC 197
+ D C
Sbjct: 5508 QRDPVSGFC 5516
>AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-77J13 on chromosome 1 Contains part of
the gene for hemicentin. ).
Length = 5635
Score = 147 bits (355), Expect = 3e-35
Identities = 77/182 (42%), Positives = 97/182 (53%), Gaps = 9/182 (4%)
Frame = +3
Query: 12 NTIGSFRCV--CGPGYRPAGRGVRGRD--ECAVRPPPCDQLCHNTDGSYDCLCRTGYELD 179
NTIGS+RCV CG G+R G+ +D EC PC Q C N GS+ C C GY+L
Sbjct: 5166 NTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQRCFNAIGSFHCGCEPGYQLK 5224
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECS--CEDGYEK-RGDACVDINECHE-EGV 347
G C DV+EC ++ Q C NT G Y+C C +G K C+DI+EC +
Sbjct: 5225 --GRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQ 5282
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQAPCRNYAGGYRCDCP 524
C C N GS+RCVCPRGYR G C+D +EC Q + C C N G ++C CP
Sbjct: 5283 CRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICP 5342
Query: 525 VG 530
G
Sbjct: 5343 PG 5344
Score = 138 bits (335), Expect = 9e-33
Identities = 75/185 (40%), Positives = 94/185 (50%), Gaps = 9/185 (4%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRD 203
S +C G G DECA P C CHN G+Y C C G + DG C+D
Sbjct: 5089 SNQCPSGFTLDSVGPFCADEDECAAGNP-CSHSCHNAMGTYYCSCPKGLTIAADGRTCQD 5147
Query: 204 VDECERDTHTCQ--QICSNTEGSYEC--SCEDGYEKRGD--ACVDINECHEEGVCPSPGR 365
+DEC HTC Q C NT GSY C C G+ + D +C DINEC E C R
Sbjct: 5148 IDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQ--R 5205
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGRCQAPCRNYAGGYRCD--CPVGTV 536
C N +GSF C C GY+L +G +C+D +EC Q R C+N GGY+C CP G
Sbjct: 5206 CFNAIGSFHCGCEPGYQL--KGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMT 5263
Query: 537 RSPSG 551
++ +G
Sbjct: 5264 KAENG 5268
Score = 132 bits (318), Expect = 1e-30
Identities = 70/162 (43%), Positives = 84/162 (51%), Gaps = 6/162 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDC--LCRTGYEL 176
R N IGSF C C PGY+ GR +EC DQ C NT G Y C LC G
Sbjct: 5205 RCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTK 5264
Query: 177 DEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKR--GDACVDINECHEEG 344
E+G C D+DEC+ TH C+ QIC NT GSY C C GY + G C+DINEC E+
Sbjct: 5265 AENG-TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINEC-EQV 5322
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG 470
P +C N GSF+C+CP G L +G C + G
Sbjct: 5323 PKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYG 5364
Score = 85.0 bits (201), Expect = 2e-16
Identities = 57/186 (30%), Positives = 76/186 (40%), Gaps = 8/186 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECA--VRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT GSF+C+C PG G G CA R P + + + R Y+ +
Sbjct: 5332 NTPGSFKCICPPGQHLLGDG----KSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQH 5387
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGR 365
+ + + S T + +C +G E D CVDI+EC C
Sbjct: 5388 YRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQH--E 5445
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC--QAPCRNYAGGYRC---DCPV 527
C N GS++C+CP GY+L G C D DEC Q C C N G Y+C CP
Sbjct: 5446 CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPP 5505
Query: 528 GTVRSP 545
R P
Sbjct: 5506 NYQRDP 5511
Score = 47.6 bits (108), Expect = 3e-05
Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 7/69 (10%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPC--DQLCHNTDGSYDCL---CRTGY 170
NT GS++C+C PGY+ G+ + DEC + C +++C N GSY C+ C Y
Sbjct: 5448 NTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNY 5507
Query: 171 ELDEDGANC 197
+ D C
Sbjct: 5508 QRDPVSGFC 5516
>AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-164L12 on chromosome 1 Contains part of
the gene for hemicentin. ).
Length = 5635
Score = 147 bits (355), Expect = 3e-35
Identities = 77/182 (42%), Positives = 97/182 (53%), Gaps = 9/182 (4%)
Frame = +3
Query: 12 NTIGSFRCV--CGPGYRPAGRGVRGRD--ECAVRPPPCDQLCHNTDGSYDCLCRTGYELD 179
NTIGS+RCV CG G+R G+ +D EC PC Q C N GS+ C C GY+L
Sbjct: 5166 NTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQRCFNAIGSFHCGCEPGYQLK 5224
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECS--CEDGYEK-RGDACVDINECHE-EGV 347
G C DV+EC ++ Q C NT G Y+C C +G K C+DI+EC +
Sbjct: 5225 --GRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQ 5282
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQAPCRNYAGGYRCDCP 524
C C N GS+RCVCPRGYR G C+D +EC Q + C C N G ++C CP
Sbjct: 5283 CRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICP 5342
Query: 525 VG 530
G
Sbjct: 5343 PG 5344
Score = 138 bits (335), Expect = 9e-33
Identities = 75/185 (40%), Positives = 94/185 (50%), Gaps = 9/185 (4%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRD 203
S +C G G DECA P C CHN G+Y C C G + DG C+D
Sbjct: 5089 SNQCPSGFTLDSVGPFCADEDECAAGNP-CSHSCHNAMGTYYCSCPKGLTIAADGRTCQD 5147
Query: 204 VDECERDTHTCQ--QICSNTEGSYEC--SCEDGYEKRGD--ACVDINECHEEGVCPSPGR 365
+DEC HTC Q C NT GSY C C G+ + D +C DINEC E C R
Sbjct: 5148 IDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQ--R 5205
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGRCQAPCRNYAGGYRCD--CPVGTV 536
C N +GSF C C GY+L +G +C+D +EC Q R C+N GGY+C CP G
Sbjct: 5206 CFNAIGSFHCGCEPGYQL--KGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMT 5263
Query: 537 RSPSG 551
++ +G
Sbjct: 5264 KAENG 5268
Score = 132 bits (318), Expect = 1e-30
Identities = 70/162 (43%), Positives = 84/162 (51%), Gaps = 6/162 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDC--LCRTGYEL 176
R N IGSF C C PGY+ GR +EC DQ C NT G Y C LC G
Sbjct: 5205 RCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTK 5264
Query: 177 DEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKR--GDACVDINECHEEG 344
E+G C D+DEC+ TH C+ QIC NT GSY C C GY + G C+DINEC E+
Sbjct: 5265 AENG-TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINEC-EQV 5322
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG 470
P +C N GSF+C+CP G L +G C + G
Sbjct: 5323 PKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYG 5364
Score = 85.0 bits (201), Expect = 2e-16
Identities = 57/186 (30%), Positives = 76/186 (40%), Gaps = 8/186 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECA--VRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT GSF+C+C PG G G CA R P + + + R Y+ +
Sbjct: 5332 NTPGSFKCICPPGQHLLGDG----KSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQH 5387
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGR 365
+ + + S T + +C +G E D CVDI+EC C
Sbjct: 5388 YRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQH--E 5445
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC--QAPCRNYAGGYRC---DCPV 527
C N GS++C+CP GY+L G C D DEC Q C C N G Y+C CP
Sbjct: 5446 CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPP 5505
Query: 528 GTVRSP 545
R P
Sbjct: 5506 NYQRDP 5511
Score = 47.6 bits (108), Expect = 3e-05
Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 7/69 (10%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPC--DQLCHNTDGSYDCL---CRTGY 170
NT GS++C+C PGY+ G+ + DEC + C +++C N GSY C+ C Y
Sbjct: 5448 NTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNY 5507
Query: 171 ELDEDGANC 197
+ D C
Sbjct: 5508 QRDPVSGFC 5516
>AL133553-4|CAI17860.1| 240|Homo sapiens protein ( e PRG4 gene for
proteoglycan 4 ).).
Length = 240
Score = 147 bits (355), Expect = 3e-35
Identities = 80/188 (42%), Positives = 94/188 (50%), Gaps = 12/188 (6%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDC--LCRTGYELDEDGA 191
IGSF C C PGY+ GR +EC DQ C NT G Y C LC G E+G
Sbjct: 2 IGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG- 60
Query: 192 NCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKR--GDACVDINECHEEGVCPSP 359
C D+DEC+ TH C+ QIC NT GSY C C GY + G C+DI+EC C
Sbjct: 61 TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDIDECENTDACQH- 119
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC--QAPCRNYAGGYRC---DC 521
C N GS++C+CP GY+L G C D DEC Q C C N G Y+C C
Sbjct: 120 -ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPC 178
Query: 522 PVGTVRSP 545
P R P
Sbjct: 179 PPNYQRDP 186
Score = 117 bits (281), Expect = 3e-26
Identities = 63/155 (40%), Positives = 81/155 (52%), Gaps = 11/155 (7%)
Frame = +3
Query: 12 NTIGSFRCV--CGPGYRPAGRGVR-GRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYEL 176
NT G ++C+ C G A G DEC C +Q+C NT GSY C+C GY
Sbjct: 39 NTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRS 98
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVC 350
G C D+DECE +T CQ C NT GSY+C C GY+ G C DI+EC E+ V
Sbjct: 99 QGVGRPCMDIDECE-NTDACQHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVH 157
Query: 351 PSPGR-CVNLLGSFRCV---CPRGYRLDAEGARCV 443
P R C N+ GS++C+ CP Y+ D C+
Sbjct: 158 CGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCL 192
>AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-174L6 on chromosome 1 Contains the3' end
of the gene for hemicentin, the PRG4 gene for
proteoglycan 4 ).
Length = 5635
Score = 147 bits (355), Expect = 3e-35
Identities = 77/182 (42%), Positives = 97/182 (53%), Gaps = 9/182 (4%)
Frame = +3
Query: 12 NTIGSFRCV--CGPGYRPAGRGVRGRD--ECAVRPPPCDQLCHNTDGSYDCLCRTGYELD 179
NTIGS+RCV CG G+R G+ +D EC PC Q C N GS+ C C GY+L
Sbjct: 5166 NTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQRCFNAIGSFHCGCEPGYQLK 5224
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECS--CEDGYEK-RGDACVDINECHE-EGV 347
G C DV+EC ++ Q C NT G Y+C C +G K C+DI+EC +
Sbjct: 5225 --GRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQ 5282
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQAPCRNYAGGYRCDCP 524
C C N GS+RCVCPRGYR G C+D +EC Q + C C N G ++C CP
Sbjct: 5283 CRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICP 5342
Query: 525 VG 530
G
Sbjct: 5343 PG 5344
Score = 138 bits (335), Expect = 9e-33
Identities = 75/185 (40%), Positives = 94/185 (50%), Gaps = 9/185 (4%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRD 203
S +C G G DECA P C CHN G+Y C C G + DG C+D
Sbjct: 5089 SNQCPSGFTLDSVGPFCADEDECAAGNP-CSHSCHNAMGTYYCSCPKGLTIAADGRTCQD 5147
Query: 204 VDECERDTHTCQ--QICSNTEGSYEC--SCEDGYEKRGD--ACVDINECHEEGVCPSPGR 365
+DEC HTC Q C NT GSY C C G+ + D +C DINEC E C R
Sbjct: 5148 IDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQ--R 5205
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGRCQAPCRNYAGGYRCD--CPVGTV 536
C N +GSF C C GY+L +G +C+D +EC Q R C+N GGY+C CP G
Sbjct: 5206 CFNAIGSFHCGCEPGYQL--KGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMT 5263
Query: 537 RSPSG 551
++ +G
Sbjct: 5264 KAENG 5268
Score = 132 bits (318), Expect = 1e-30
Identities = 70/162 (43%), Positives = 84/162 (51%), Gaps = 6/162 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDC--LCRTGYEL 176
R N IGSF C C PGY+ GR +EC DQ C NT G Y C LC G
Sbjct: 5205 RCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTK 5264
Query: 177 DEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKR--GDACVDINECHEEG 344
E+G C D+DEC+ TH C+ QIC NT GSY C C GY + G C+DINEC E+
Sbjct: 5265 AENG-TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINEC-EQV 5322
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG 470
P +C N GSF+C+CP G L +G C + G
Sbjct: 5323 PKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYG 5364
Score = 85.0 bits (201), Expect = 2e-16
Identities = 57/186 (30%), Positives = 76/186 (40%), Gaps = 8/186 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECA--VRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT GSF+C+C PG G G CA R P + + + R Y+ +
Sbjct: 5332 NTPGSFKCICPPGQHLLGDG----KSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQH 5387
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGR 365
+ + + S T + +C +G E D CVDI+EC C
Sbjct: 5388 YRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQH--E 5445
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC--QAPCRNYAGGYRC---DCPV 527
C N GS++C+CP GY+L G C D DEC Q C C N G Y+C CP
Sbjct: 5446 CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPP 5505
Query: 528 GTVRSP 545
R P
Sbjct: 5506 NYQRDP 5511
Score = 47.6 bits (108), Expect = 3e-05
Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 7/69 (10%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPC--DQLCHNTDGSYDCL---CRTGY 170
NT GS++C+C PGY+ G+ + DEC + C +++C N GSY C+ C Y
Sbjct: 5448 NTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNY 5507
Query: 171 ELDEDGANC 197
+ D C
Sbjct: 5508 QRDPVSGFC 5516
>AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-153O3 on chromosome 1 Contains part of
the gene for hemicentin. ).
Length = 5635
Score = 147 bits (355), Expect = 3e-35
Identities = 77/182 (42%), Positives = 97/182 (53%), Gaps = 9/182 (4%)
Frame = +3
Query: 12 NTIGSFRCV--CGPGYRPAGRGVRGRD--ECAVRPPPCDQLCHNTDGSYDCLCRTGYELD 179
NTIGS+RCV CG G+R G+ +D EC PC Q C N GS+ C C GY+L
Sbjct: 5166 NTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQRCFNAIGSFHCGCEPGYQLK 5224
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECS--CEDGYEK-RGDACVDINECHE-EGV 347
G C DV+EC ++ Q C NT G Y+C C +G K C+DI+EC +
Sbjct: 5225 --GRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQ 5282
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQAPCRNYAGGYRCDCP 524
C C N GS+RCVCPRGYR G C+D +EC Q + C C N G ++C CP
Sbjct: 5283 CRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICP 5342
Query: 525 VG 530
G
Sbjct: 5343 PG 5344
Score = 138 bits (335), Expect = 9e-33
Identities = 75/185 (40%), Positives = 94/185 (50%), Gaps = 9/185 (4%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRD 203
S +C G G DECA P C CHN G+Y C C G + DG C+D
Sbjct: 5089 SNQCPSGFTLDSVGPFCADEDECAAGNP-CSHSCHNAMGTYYCSCPKGLTIAADGRTCQD 5147
Query: 204 VDECERDTHTCQ--QICSNTEGSYEC--SCEDGYEKRGD--ACVDINECHEEGVCPSPGR 365
+DEC HTC Q C NT GSY C C G+ + D +C DINEC E C R
Sbjct: 5148 IDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQ--R 5205
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGRCQAPCRNYAGGYRCD--CPVGTV 536
C N +GSF C C GY+L +G +C+D +EC Q R C+N GGY+C CP G
Sbjct: 5206 CFNAIGSFHCGCEPGYQL--KGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMT 5263
Query: 537 RSPSG 551
++ +G
Sbjct: 5264 KAENG 5268
Score = 132 bits (318), Expect = 1e-30
Identities = 70/162 (43%), Positives = 84/162 (51%), Gaps = 6/162 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDC--LCRTGYEL 176
R N IGSF C C PGY+ GR +EC DQ C NT G Y C LC G
Sbjct: 5205 RCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTK 5264
Query: 177 DEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKR--GDACVDINECHEEG 344
E+G C D+DEC+ TH C+ QIC NT GSY C C GY + G C+DINEC E+
Sbjct: 5265 AENG-TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINEC-EQV 5322
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG 470
P +C N GSF+C+CP G L +G C + G
Sbjct: 5323 PKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYG 5364
Score = 85.0 bits (201), Expect = 2e-16
Identities = 57/186 (30%), Positives = 76/186 (40%), Gaps = 8/186 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECA--VRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT GSF+C+C PG G G CA R P + + + R Y+ +
Sbjct: 5332 NTPGSFKCICPPGQHLLGDG----KSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQH 5387
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGR 365
+ + + S T + +C +G E D CVDI+EC C
Sbjct: 5388 YRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQH--E 5445
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC--QAPCRNYAGGYRC---DCPV 527
C N GS++C+CP GY+L G C D DEC Q C C N G Y+C CP
Sbjct: 5446 CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPP 5505
Query: 528 GTVRSP 545
R P
Sbjct: 5506 NYQRDP 5511
Score = 47.6 bits (108), Expect = 3e-05
Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 7/69 (10%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPC--DQLCHNTDGSYDCL---CRTGY 170
NT GS++C+C PGY+ G+ + DEC + C +++C N GSY C+ C Y
Sbjct: 5448 NTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNY 5507
Query: 171 ELDEDGANC 197
+ D C
Sbjct: 5508 QRDPVSGFC 5516
>AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-118G19 on chromosome 1q25.1-31.1 Contains
the 5' end of the gene for hemicentin. ).
Length = 5635
Score = 147 bits (355), Expect = 3e-35
Identities = 77/182 (42%), Positives = 97/182 (53%), Gaps = 9/182 (4%)
Frame = +3
Query: 12 NTIGSFRCV--CGPGYRPAGRGVRGRD--ECAVRPPPCDQLCHNTDGSYDCLCRTGYELD 179
NTIGS+RCV CG G+R G+ +D EC PC Q C N GS+ C C GY+L
Sbjct: 5166 NTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQRCFNAIGSFHCGCEPGYQLK 5224
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECS--CEDGYEK-RGDACVDINECHE-EGV 347
G C DV+EC ++ Q C NT G Y+C C +G K C+DI+EC +
Sbjct: 5225 --GRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQ 5282
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQAPCRNYAGGYRCDCP 524
C C N GS+RCVCPRGYR G C+D +EC Q + C C N G ++C CP
Sbjct: 5283 CRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICP 5342
Query: 525 VG 530
G
Sbjct: 5343 PG 5344
Score = 138 bits (335), Expect = 9e-33
Identities = 75/185 (40%), Positives = 94/185 (50%), Gaps = 9/185 (4%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRD 203
S +C G G DECA P C CHN G+Y C C G + DG C+D
Sbjct: 5089 SNQCPSGFTLDSVGPFCADEDECAAGNP-CSHSCHNAMGTYYCSCPKGLTIAADGRTCQD 5147
Query: 204 VDECERDTHTCQ--QICSNTEGSYEC--SCEDGYEKRGD--ACVDINECHEEGVCPSPGR 365
+DEC HTC Q C NT GSY C C G+ + D +C DINEC E C R
Sbjct: 5148 IDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQ--R 5205
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGRCQAPCRNYAGGYRCD--CPVGTV 536
C N +GSF C C GY+L +G +C+D +EC Q R C+N GGY+C CP G
Sbjct: 5206 CFNAIGSFHCGCEPGYQL--KGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMT 5263
Query: 537 RSPSG 551
++ +G
Sbjct: 5264 KAENG 5268
Score = 132 bits (318), Expect = 1e-30
Identities = 70/162 (43%), Positives = 84/162 (51%), Gaps = 6/162 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDC--LCRTGYEL 176
R N IGSF C C PGY+ GR +EC DQ C NT G Y C LC G
Sbjct: 5205 RCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTK 5264
Query: 177 DEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKR--GDACVDINECHEEG 344
E+G C D+DEC+ TH C+ QIC NT GSY C C GY + G C+DINEC E+
Sbjct: 5265 AENG-TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINEC-EQV 5322
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG 470
P +C N GSF+C+CP G L +G C + G
Sbjct: 5323 PKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYG 5364
Score = 85.0 bits (201), Expect = 2e-16
Identities = 57/186 (30%), Positives = 76/186 (40%), Gaps = 8/186 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECA--VRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT GSF+C+C PG G G CA R P + + + R Y+ +
Sbjct: 5332 NTPGSFKCICPPGQHLLGDG----KSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQH 5387
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGR 365
+ + + S T + +C +G E D CVDI+EC C
Sbjct: 5388 YRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQH--E 5445
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC--QAPCRNYAGGYRC---DCPV 527
C N GS++C+CP GY+L G C D DEC Q C C N G Y+C CP
Sbjct: 5446 CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPP 5505
Query: 528 GTVRSP 545
R P
Sbjct: 5506 NYQRDP 5511
Score = 47.6 bits (108), Expect = 3e-05
Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 7/69 (10%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPC--DQLCHNTDGSYDCL---CRTGY 170
NT GS++C+C PGY+ G+ + DEC + C +++C N GSY C+ C Y
Sbjct: 5448 NTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNY 5507
Query: 171 ELDEDGANC 197
+ D C
Sbjct: 5508 QRDPVSGFC 5516
>AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-248A21 on chromosome 1q31.1-31.3 Contains
part of the gene for hemicentin (FIBL-6). ).
Length = 5635
Score = 147 bits (355), Expect = 3e-35
Identities = 77/182 (42%), Positives = 97/182 (53%), Gaps = 9/182 (4%)
Frame = +3
Query: 12 NTIGSFRCV--CGPGYRPAGRGVRGRD--ECAVRPPPCDQLCHNTDGSYDCLCRTGYELD 179
NTIGS+RCV CG G+R G+ +D EC PC Q C N GS+ C C GY+L
Sbjct: 5166 NTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQRCFNAIGSFHCGCEPGYQLK 5224
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECS--CEDGYEK-RGDACVDINECHE-EGV 347
G C DV+EC ++ Q C NT G Y+C C +G K C+DI+EC +
Sbjct: 5225 --GRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQ 5282
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQAPCRNYAGGYRCDCP 524
C C N GS+RCVCPRGYR G C+D +EC Q + C C N G ++C CP
Sbjct: 5283 CRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICP 5342
Query: 525 VG 530
G
Sbjct: 5343 PG 5344
Score = 138 bits (335), Expect = 9e-33
Identities = 75/185 (40%), Positives = 94/185 (50%), Gaps = 9/185 (4%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRD 203
S +C G G DECA P C CHN G+Y C C G + DG C+D
Sbjct: 5089 SNQCPSGFTLDSVGPFCADEDECAAGNP-CSHSCHNAMGTYYCSCPKGLTIAADGRTCQD 5147
Query: 204 VDECERDTHTCQ--QICSNTEGSYEC--SCEDGYEKRGD--ACVDINECHEEGVCPSPGR 365
+DEC HTC Q C NT GSY C C G+ + D +C DINEC E C R
Sbjct: 5148 IDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQ--R 5205
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGRCQAPCRNYAGGYRCD--CPVGTV 536
C N +GSF C C GY+L +G +C+D +EC Q R C+N GGY+C CP G
Sbjct: 5206 CFNAIGSFHCGCEPGYQL--KGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMT 5263
Query: 537 RSPSG 551
++ +G
Sbjct: 5264 KAENG 5268
Score = 132 bits (318), Expect = 1e-30
Identities = 70/162 (43%), Positives = 84/162 (51%), Gaps = 6/162 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDC--LCRTGYEL 176
R N IGSF C C PGY+ GR +EC DQ C NT G Y C LC G
Sbjct: 5205 RCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTK 5264
Query: 177 DEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKR--GDACVDINECHEEG 344
E+G C D+DEC+ TH C+ QIC NT GSY C C GY + G C+DINEC E+
Sbjct: 5265 AENG-TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINEC-EQV 5322
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG 470
P +C N GSF+C+CP G L +G C + G
Sbjct: 5323 PKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYG 5364
Score = 85.0 bits (201), Expect = 2e-16
Identities = 57/186 (30%), Positives = 76/186 (40%), Gaps = 8/186 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECA--VRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT GSF+C+C PG G G CA R P + + + R Y+ +
Sbjct: 5332 NTPGSFKCICPPGQHLLGDG----KSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQH 5387
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGR 365
+ + + S T + +C +G E D CVDI+EC C
Sbjct: 5388 YRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQH--E 5445
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC--QAPCRNYAGGYRC---DCPV 527
C N GS++C+CP GY+L G C D DEC Q C C N G Y+C CP
Sbjct: 5446 CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPP 5505
Query: 528 GTVRSP 545
R P
Sbjct: 5506 NYQRDP 5511
Score = 47.6 bits (108), Expect = 3e-05
Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 7/69 (10%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPC--DQLCHNTDGSYDCL---CRTGY 170
NT GS++C+C PGY+ G+ + DEC + C +++C N GSY C+ C Y
Sbjct: 5448 NTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNY 5507
Query: 171 ELDEDGANC 197
+ D C
Sbjct: 5508 QRDPVSGFC 5516
>AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein.
Length = 2673
Score = 147 bits (355), Expect = 3e-35
Identities = 77/182 (42%), Positives = 97/182 (53%), Gaps = 9/182 (4%)
Frame = +3
Query: 12 NTIGSFRCV--CGPGYRPAGRGVRGRD--ECAVRPPPCDQLCHNTDGSYDCLCRTGYELD 179
NTIGS+RCV CG G+R G+ +D EC PC Q C N GS+ C C GY+L
Sbjct: 2204 NTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQRCFNAIGSFHCGCEPGYQLK 2262
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECS--CEDGYEK-RGDACVDINECHE-EGV 347
G C DV+EC ++ Q C NT G Y+C C +G K C+DI+EC +
Sbjct: 2263 --GRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQ 2320
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQAPCRNYAGGYRCDCP 524
C C N GS+RCVCPRGYR G C+D +EC Q + C C N G ++C CP
Sbjct: 2321 CRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICP 2380
Query: 525 VG 530
G
Sbjct: 2381 PG 2382
Score = 138 bits (335), Expect = 9e-33
Identities = 75/185 (40%), Positives = 94/185 (50%), Gaps = 9/185 (4%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRD 203
S +C G G DECA P C CHN G+Y C C G + DG C+D
Sbjct: 2127 SNQCPSGFTLDSVGPFCADEDECAAGNP-CSHSCHNAMGTYYCSCPKGLTIAADGRTCQD 2185
Query: 204 VDECERDTHTCQ--QICSNTEGSYEC--SCEDGYEKRGD--ACVDINECHEEGVCPSPGR 365
+DEC HTC Q C NT GSY C C G+ + D +C DINEC E C R
Sbjct: 2186 IDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQ--R 2243
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGRCQAPCRNYAGGYRCD--CPVGTV 536
C N +GSF C C GY+L +G +C+D +EC Q R C+N GGY+C CP G
Sbjct: 2244 CFNAIGSFHCGCEPGYQL--KGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMT 2301
Query: 537 RSPSG 551
++ +G
Sbjct: 2302 KAENG 2306
Score = 132 bits (318), Expect = 1e-30
Identities = 70/162 (43%), Positives = 84/162 (51%), Gaps = 6/162 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDC--LCRTGYEL 176
R N IGSF C C PGY+ GR +EC DQ C NT G Y C LC G
Sbjct: 2243 RCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTK 2302
Query: 177 DEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKR--GDACVDINECHEEG 344
E+G C D+DEC+ TH C+ QIC NT GSY C C GY + G C+DINEC E+
Sbjct: 2303 AENG-TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINEC-EQV 2360
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG 470
P +C N GSF+C+CP G L +G C + G
Sbjct: 2361 PKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYG 2402
Score = 85.0 bits (201), Expect = 2e-16
Identities = 57/186 (30%), Positives = 76/186 (40%), Gaps = 8/186 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECA--VRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT GSF+C+C PG G G CA R P + + + R Y+ +
Sbjct: 2370 NTPGSFKCICPPGQHLLGDG----KSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQH 2425
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGR 365
+ + + S T + +C +G E D CVDI+EC C
Sbjct: 2426 YRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQH--E 2483
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC--QAPCRNYAGGYRC---DCPV 527
C N GS++C+CP GY+L G C D DEC Q C C N G Y+C CP
Sbjct: 2484 CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPP 2543
Query: 528 GTVRSP 545
R P
Sbjct: 2544 NYQRDP 2549
Score = 47.6 bits (108), Expect = 3e-05
Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 7/69 (10%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPC--DQLCHNTDGSYDCL---CRTGY 170
NT GS++C+C PGY+ G+ + DEC + C +++C N GSY C+ C Y
Sbjct: 2486 NTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNY 2545
Query: 171 ELDEDGANC 197
+ D C
Sbjct: 2546 QRDPVSGFC 2554
>AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein.
Length = 5636
Score = 146 bits (354), Expect = 5e-35
Identities = 77/182 (42%), Positives = 96/182 (52%), Gaps = 9/182 (4%)
Frame = +3
Query: 12 NTIGSFRCV--CGPGYRPAGRGVRGRD--ECAVRPPPCDQLCHNTDGSYDCLCRTGYELD 179
NTIGS+RCV CG G+R G+ +D EC PC Q C N GS+ C C GY+L
Sbjct: 5167 NTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQRCFNAIGSFHCGCEPGYQLK 5225
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECS--CEDGYEK-RGDACVDINECHE-EGV 347
G C DV+EC ++ Q C NT G Y+C C +G K C+DI+EC +
Sbjct: 5226 --GRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQ 5283
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQAPCRNYAGGYRCDCP 524
C C N S+RCVCPRGYR G C+D DEC Q + C C N G ++C CP
Sbjct: 5284 CRYNQICENTRSSYRCVCPRGYRSQGVGRPCMDIDECEQVPKPCAHQCSNTPGSFKCICP 5343
Query: 525 VG 530
G
Sbjct: 5344 PG 5345
Score = 138 bits (335), Expect = 9e-33
Identities = 75/185 (40%), Positives = 94/185 (50%), Gaps = 9/185 (4%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRD 203
S +C G G DECA P C CHN G+Y C C G + DG C+D
Sbjct: 5090 SNQCPSGFTLDSVGPFCADEDECAAGNP-CSHSCHNAMGTYYCSCPKGLTIAADGRTCQD 5148
Query: 204 VDECERDTHTCQ--QICSNTEGSYEC--SCEDGYEKRGD--ACVDINECHEEGVCPSPGR 365
+DEC HTC Q C NT GSY C C G+ + D +C DINEC E C R
Sbjct: 5149 IDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQ--R 5206
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGRCQAPCRNYAGGYRCD--CPVGTV 536
C N +GSF C C GY+L +G +C+D +EC Q R C+N GGY+C CP G
Sbjct: 5207 CFNAIGSFHCGCEPGYQL--KGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMT 5264
Query: 537 RSPSG 551
++ +G
Sbjct: 5265 KAENG 5269
Score = 127 bits (307), Expect = 2e-29
Identities = 68/162 (41%), Positives = 83/162 (51%), Gaps = 6/162 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDC--LCRTGYEL 176
R N IGSF C C PGY+ GR +EC DQ C NT G Y C LC G
Sbjct: 5206 RCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTK 5265
Query: 177 DEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKR--GDACVDINECHEEG 344
E+G C D+DEC+ TH C+ QIC NT SY C C GY + G C+DI+EC E+
Sbjct: 5266 AENG-TCIDIDECKDGTHQCRYNQICENTRSSYRCVCPRGYRSQGVGRPCMDIDEC-EQV 5323
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG 470
P +C N GSF+C+CP G L +G C + G
Sbjct: 5324 PKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYG 5365
Score = 85.0 bits (201), Expect = 2e-16
Identities = 57/186 (30%), Positives = 76/186 (40%), Gaps = 8/186 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECA--VRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT GSF+C+C PG G G CA R P + + + R Y+ +
Sbjct: 5333 NTPGSFKCICPPGQHLLGDG----KSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQH 5388
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGR 365
+ + + S T + +C +G E D CVDI+EC C
Sbjct: 5389 YRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQH--E 5446
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRC--QAPCRNYAGGYRC---DCPV 527
C N GS++C+CP GY+L G C D DEC Q C C N G Y+C CP
Sbjct: 5447 CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPP 5506
Query: 528 GTVRSP 545
R P
Sbjct: 5507 NYQRDP 5512
Score = 47.6 bits (108), Expect = 3e-05
Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 7/69 (10%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPC--DQLCHNTDGSYDCL---CRTGY 170
NT GS++C+C PGY+ G+ + DEC + C +++C N GSY C+ C Y
Sbjct: 5449 NTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNY 5508
Query: 171 ELDEDGANC 197
+ D C
Sbjct: 5509 QRDPVSGFC 5517
>Z37976-1|CAA86030.1| 1821|Homo sapiens LTBP-2 precursor protein.
Length = 1821
Score = 145 bits (352), Expect = 8e-35
Identities = 77/181 (42%), Positives = 92/181 (50%), Gaps = 7/181 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN +RCVC PGY+ P+ +EC P C N GSY C C GY L
Sbjct: 862 VNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCQGKGRCINRVGSYSCFCYPGYTLAT 921
Query: 183 DGA--NCRDVDECERDTHTCQQICSNTEGSYECSCEDGY-EKRGDACVDINECHEEGVCP 353
GA C+D++ECE+ C+NTEGSY C C+ GY R C DINEC G CP
Sbjct: 922 SGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKGHCQDINECRHPGTCP 981
Query: 354 SPGRCVNLLGSFRCV-CPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPV 527
GRCVN GS+ C+ C GYR + CVD +EC G C C N G +RC C
Sbjct: 982 D-GRCVNSPGSYTCLACEEGYR--GQSGSCVDVNECLTPGVCAHGKCTNLEGSFRCSCEQ 1038
Query: 528 G 530
G
Sbjct: 1039 G 1039
Score = 142 bits (344), Expect = 7e-34
Identities = 75/179 (41%), Positives = 100/179 (55%), Gaps = 8/179 (4%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGV----RGRDECAVRPPPCD-QLCHNTDGSYDCLCRTG 167
R +N +GS+ C C PGY A G + +EC +P C C NT+GSY C C G
Sbjct: 901 RCINRVGSYSCFCYPGYTLATSGATQECQDINECE-QPGVCSGGQCTNTEGSYHCECDQG 959
Query: 168 YELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYEC-SCEDGYEKRGDACVDINECHEE 341
Y + G +C+D++EC R TC C N+ GSY C +CE+GY + +CVD+NEC
Sbjct: 960 YIMVRKG-HCQDINEC-RHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTP 1017
Query: 342 GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP-CRNYAGGYRC 515
GVC + G+C NL GSFRC C +GY + ++ C D DECA C C N G + C
Sbjct: 1018 GVC-AHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFAC 1075
Score = 142 bits (343), Expect = 1e-33
Identities = 79/184 (42%), Positives = 97/184 (52%), Gaps = 8/184 (4%)
Frame = +3
Query: 3 RGVNTIGSFRCV-CGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYEL 176
R VN+ GS+ C+ C GYR +EC + P C C N +GS+ C C GYE+
Sbjct: 984 RCVNSPGSYTCLACEEGYRGQSGSCVDVNEC-LTPGVCAHGKCTNLEGSFRCSCEQGYEV 1042
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECS-CEDGY--EKRGDACVDINECHEEGV 347
D C+DVDEC +C NTEGS+ CS CE+GY + G AC D++EC GV
Sbjct: 1043 TSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAFPGV 1102
Query: 348 CPSPGRCVNLLGSFRCV-CPRGYRLDAEGARCVDRDEC--AQTGRCQAPCRNYAGGYRCD 518
CPS G C N GSF C C GYR G C D DEC Q+ C+N G Y+C
Sbjct: 1103 CPS-GVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCL 1161
Query: 519 CPVG 530
CP G
Sbjct: 1162 CPQG 1165
Score = 140 bits (339), Expect = 3e-33
Identities = 73/188 (38%), Positives = 98/188 (52%), Gaps = 8/188 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPPCDQLCHNTDGSYDC-LCRTGYELDE 182
N GSFRC C GY +G + DECA R LC NT+GS+ C C GY ++E
Sbjct: 1027 NLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNE 1086
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECS-CEDGYEKR--GDACVDINECHEEGVCP 353
DG C D+DEC +C+NT GS+ C C+ GY GD+C D++EC +
Sbjct: 1087 DGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSC 1146
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC--QAPCRNYAGGYRCDCPV 527
G C N +GS++C+CP+G++L A G C D +EC C C N G + C C
Sbjct: 1147 LGGECKNTVGSYQCLCPQGFQL-ANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAP 1205
Query: 528 GTVRSPSG 551
G V + G
Sbjct: 1206 GFVSAEGG 1213
Score = 138 bits (334), Expect = 1e-32
Identities = 72/181 (39%), Positives = 97/181 (53%), Gaps = 10/181 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+N+ GSF C+C PG+ A G + DECA P C NT+GS++CLC TG++
Sbjct: 1193 LNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSP 1252
Query: 183 DGANCRDVDECER--DTHTCQQICSNTEGSYEC--SCEDGYEK--RGDACVDINECHEEG 344
+ C D+DECE D C N+ GSY C C+ G+ GD C+DI+EC +
Sbjct: 1253 ESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGD-CIDIDECANDT 1311
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQAP-CRNYAGGYRCD 518
+C S G C N GSFRC+C +G+ + G CVD +EC C A C N G + C
Sbjct: 1312 MCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCL 1371
Query: 519 C 521
C
Sbjct: 1372 C 1372
Score = 129 bits (312), Expect = 6e-30
Identities = 74/190 (38%), Positives = 100/190 (52%), Gaps = 10/190 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA-GRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDED 185
NT+GS++C+C G++ A G +EC C N+ GS+ CLC G+ E
Sbjct: 1153 NTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEG 1212
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEG--VCP 353
G +C+DVDEC C NTEGS+ C CE G++ ++ CVDI+EC + G VC
Sbjct: 1213 GTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVC- 1271
Query: 354 SPGRCVNLLGSFRCV--CPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRCDC 521
+C N GS+RCV C G+ + A C+D DECA C + C N G +RC C
Sbjct: 1272 GTWKCENSPGSYRCVLGCQPGFHM-APNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLC 1330
Query: 522 PVGTVRSPSG 551
G SPSG
Sbjct: 1331 DQGFEISPSG 1340
Score = 106 bits (254), Expect = 6e-23
Identities = 60/149 (40%), Positives = 71/149 (47%), Gaps = 6/149 (4%)
Frame = +3
Query: 123 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY--- 293
C N Y C+C GY+L A C D +EC RD + C N GSY C C GY
Sbjct: 861 CVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCQGKGRCINRVGSYSCFCYPGYTLA 920
Query: 294 -EKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG 470
C DINEC + GVC S G+C N GS+ C C +GY + +G C D +EC G
Sbjct: 921 TSGATQECQDINECEQPGVC-SGGQCTNTEGSYHCECDQGYIMVRKG-HCQDINECRHPG 978
Query: 471 RC-QAPCRNYAGGYRC-DCPVGTVRSPSG 551
C C N G Y C C G R SG
Sbjct: 979 TCPDGRCVNSPGSYTCLACEEG-YRGQSG 1006
Score = 78.6 bits (185), Expect = 1e-14
Identities = 43/102 (42%), Positives = 54/102 (52%), Gaps = 6/102 (5%)
Frame = +3
Query: 12 NTIGSFRCV--CGPGYRPAGRG-VRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYEL 176
N+ GS+RCV C PG+ A G DECA C C NTDGS+ CLC G+E+
Sbjct: 1278 NSPGSYRCVLGCQPGFHMAPNGDCIDIDECA-NDTMCGSHGFCDNTDGSFRCLCDQGFEI 1336
Query: 177 DEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYEK 299
G +C DV+ECE C +C N EGS+ C C E+
Sbjct: 1337 SPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEE 1378
Score = 59.7 bits (138), Expect = 7e-09
Identities = 37/140 (26%), Positives = 54/140 (38%), Gaps = 2/140 (1%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCED 287
PC + +C C G + C D E +IC + +G E
Sbjct: 1422 PCSSVLGRNTTQAECCCTQGATWGDACDLCPSEDSAE-----FSEICPSGKGYIPV--EG 1474
Query: 288 GYEKRGDACVDINEC--HEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA 461
+ D +EC G+CP+ GRC+N + + C+C G+ DA +C D DEC
Sbjct: 1475 AWTFGQTMYTDADECVIFGPGLCPN-GRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQ 1533
Query: 462 QTGRCQAPCRNYAGGYRCDC 521
C N G + C C
Sbjct: 1534 DLACENGECVNTEGSFHCFC 1553
Score = 58.0 bits (134), Expect = 2e-08
Identities = 31/71 (43%), Positives = 36/71 (50%), Gaps = 2/71 (2%)
Frame = +3
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRCD 518
VC PG CVNL +RCVC GY+L A C D +EC + CQ C N G Y C
Sbjct: 855 VC-GPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLR-DPCQGKGRCINRVGSYSCF 912
Query: 519 CPVGTVRSPSG 551
C G + SG
Sbjct: 913 CYPGYTLATSG 923
Score = 52.4 bits (120), Expect = 1e-06
Identities = 59/202 (29%), Positives = 77/202 (38%), Gaps = 29/202 (14%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGY-ELD 179
NT GSFRC+C G+ P+G +EC + C LC N +GS+ CLC + E D
Sbjct: 1321 NTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYD 1380
Query: 180 EDGANCR-------DVDECERDTH----TCQQICSNTEGSYECSCEDGYE-KRGDACVDI 323
+CR + E H T S +G CS G + + C
Sbjct: 1381 AQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQ 1440
Query: 324 NECHEEG--VCPSPGRCVNLLGSFRCVCP--RGYRLDAEGA------RCVDRDECAQTGR 473
+ +CPS F +CP +GY + EGA D DEC G
Sbjct: 1441 GATWGDACDLCPSEDS-----AEFSEICPSGKGY-IPVEGAWTFGQTMYTDADECVIFGP 1494
Query: 474 CQAP---CRNYAGGYRCDCPVG 530
P C N GY C C G
Sbjct: 1495 GLCPNGRCLNTVPGYVCLCNPG 1516
Score = 50.4 bits (115), Expect = 4e-06
Identities = 30/87 (34%), Positives = 38/87 (43%), Gaps = 1/87 (1%)
Frame = +3
Query: 270 ECSCEDGYEKRG-DACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
+ C GY++ C DINEC G+C CVN GS+ C C G LD +RCV
Sbjct: 605 QLECPQGYKRLNLTHCQDINECLTLGLCKD-AECVNTRGSYLCTCRPGLMLDPSRSRCVS 663
Query: 447 RDECAQTGRCQAPCRNYAGGYRCDCPV 527
D+ Q C G C P+
Sbjct: 664 -DKA--ISMLQGLCYRSLGPGTCTLPL 687
Score = 50.4 bits (115), Expect = 4e-06
Identities = 29/83 (34%), Positives = 36/83 (43%), Gaps = 4/83 (4%)
Frame = +3
Query: 57 PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECER---DT 227
PAG +EC + + C Y C C G++LD C DV+EC+
Sbjct: 1726 PAGFEGLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPA 1785
Query: 228 HTCQQ-ICSNTEGSYECSCEDGY 293
C C NTEGSY C C GY
Sbjct: 1786 VLCVHGYCENTEGSYRCHCSPGY 1808
Score = 48.8 bits (111), Expect = 1e-05
Identities = 26/69 (37%), Positives = 33/69 (47%), Gaps = 2/69 (2%)
Frame = +3
Query: 246 CSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRL 419
C NT Y C C G Y+ C D +EC ++ C + G CVN GSF C C L
Sbjct: 1502 CLNTVPGYVCLCNPGFHYDASHKKCEDHDEC-QDLACEN-GECVNTEGSFHCFCSPPLTL 1559
Query: 420 DAEGARCVD 446
D RC++
Sbjct: 1560 DLSQQRCMN 1568
Score = 48.8 bits (111), Expect = 1e-05
Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 5/74 (6%)
Frame = +3
Query: 246 CSNTEGSYECSCEDGYEKRGD--ACVDINECHE---EGVCPSPGRCVNLLGSFRCVCPRG 410
C Y C C +G++ ACVD+NEC + V G C N GS+RC C G
Sbjct: 1748 CVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPG 1807
Query: 411 YRLDAEGARCVDRD 452
Y +A C ++
Sbjct: 1808 YVAEAGPPHCTAKE 1821
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/75 (37%), Positives = 34/75 (45%), Gaps = 5/75 (6%)
Frame = +3
Query: 327 ECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG----RC-QAPCR 491
EC C + GRCV + + C C G++LDA CVD +EC C C
Sbjct: 1736 ECGILNGCEN-GRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCE 1794
Query: 492 NYAGGYRCDCPVGTV 536
N G YRC C G V
Sbjct: 1795 NTEGSYRCHCSPGYV 1809
Score = 41.9 bits (94), Expect = 0.001
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 4/85 (4%)
Frame = +3
Query: 306 DACVDINECHEEGVC-PSPGRCVN-LLGSFRCVCPRGY-RLDAEGARCVDRDECAQTGRC 476
D C + +C P P R + ++ + + CP+GY RL+ C D +EC G C
Sbjct: 575 DCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQGYKRLNL--THCQDINECLTLGLC 632
Query: 477 Q-APCRNYAGGYRCDCPVGTVRSPS 548
+ A C N G Y C C G + PS
Sbjct: 633 KDAECVNTRGSYLCTCRPGLMLDPS 657
Score = 41.1 bits (92), Expect = 0.003
Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 3/77 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPG--YRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYE 173
R +NT+ + C+C PG Y + + DEC + C+ C NT+GS+ C C
Sbjct: 1501 RCLNTVPGYVCLCNPGFHYDASHKKCEDHDEC--QDLACENGECVNTEGSFHCFCSPPLT 1558
Query: 174 LDEDGANCRDVDECERD 224
LD C + D
Sbjct: 1559 LDLSQQRCMNSTSSTED 1575
Score = 37.1 bits (82), Expect = 0.041
Identities = 32/114 (28%), Positives = 45/114 (39%), Gaps = 4/114 (3%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEG 263
+EC D C NT GSY C CR G LD + C ++ Q +C + G
Sbjct: 624 NECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRC----VSDKAISMLQGLCYRSLG 679
Query: 264 SYECS--CEDGYEKRGDACVDINEC--HEEGVCPSPGRCVNLLGSFRCVCPRGY 413
C+ K+ C + + E CP PG +FR +CP G+
Sbjct: 680 PGTCTLPLAQRITKQICCCSRVGKAWGSECEKCPLPG-----TEAFREICPAGH 728
Score = 31.1 bits (67), Expect = 2.7
Identities = 11/25 (44%), Positives = 14/25 (56%)
Frame = +3
Query: 123 CHNTDGSYDCLCRTGYELDEDGANC 197
C NT+GSY C C GY + +C
Sbjct: 1793 CENTEGSYRCHCSPGYVAEAGPPHC 1817
>S82451-1|AAB37459.1| 1821|Homo sapiens latent transforming growth
factor-beta-binding protein-2 protein.
Length = 1821
Score = 145 bits (352), Expect = 8e-35
Identities = 77/181 (42%), Positives = 92/181 (50%), Gaps = 7/181 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN +RCVC PGY+ P+ +EC P C N GSY C C GY L
Sbjct: 862 VNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCINRVGSYSCFCYPGYTLAT 921
Query: 183 DGA--NCRDVDECERDTHTCQQICSNTEGSYECSCEDGY-EKRGDACVDINECHEEGVCP 353
GA C+D++ECE+ C+NTEGSY C C+ GY R C DINEC G CP
Sbjct: 922 SGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKGHCQDINECRHPGTCP 981
Query: 354 SPGRCVNLLGSFRCV-CPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPV 527
GRCVN GS+ C+ C GYR + CVD +EC G C C N G +RC C
Sbjct: 982 D-GRCVNSPGSYTCLACEEGYR--GQSGSCVDVNECLTPGVCAHGKCTNLEGSFRCSCEQ 1038
Query: 528 G 530
G
Sbjct: 1039 G 1039
Score = 142 bits (344), Expect = 7e-34
Identities = 75/179 (41%), Positives = 100/179 (55%), Gaps = 8/179 (4%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGV----RGRDECAVRPPPCD-QLCHNTDGSYDCLCRTG 167
R +N +GS+ C C PGY A G + +EC +P C C NT+GSY C C G
Sbjct: 901 RCINRVGSYSCFCYPGYTLATSGATQECQDINECE-QPGVCSGGQCTNTEGSYHCECDQG 959
Query: 168 YELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYEC-SCEDGYEKRGDACVDINECHEE 341
Y + G +C+D++EC R TC C N+ GSY C +CE+GY + +CVD+NEC
Sbjct: 960 YIMVRKG-HCQDINEC-RHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTP 1017
Query: 342 GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP-CRNYAGGYRC 515
GVC + G+C NL GSFRC C +GY + ++ C D DECA C C N G + C
Sbjct: 1018 GVC-AHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFAC 1075
Score = 142 bits (343), Expect = 1e-33
Identities = 79/184 (42%), Positives = 97/184 (52%), Gaps = 8/184 (4%)
Frame = +3
Query: 3 RGVNTIGSFRCV-CGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYEL 176
R VN+ GS+ C+ C GYR +EC + P C C N +GS+ C C GYE+
Sbjct: 984 RCVNSPGSYTCLACEEGYRGQSGSCVDVNEC-LTPGVCAHGKCTNLEGSFRCSCEQGYEV 1042
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECS-CEDGY--EKRGDACVDINECHEEGV 347
D C+DVDEC +C NTEGS+ CS CE+GY + G AC D++EC GV
Sbjct: 1043 TSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAFPGV 1102
Query: 348 CPSPGRCVNLLGSFRCV-CPRGYRLDAEGARCVDRDEC--AQTGRCQAPCRNYAGGYRCD 518
CPS G C N GSF C C GYR G C D DEC Q+ C+N G Y+C
Sbjct: 1103 CPS-GVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCL 1161
Query: 519 CPVG 530
CP G
Sbjct: 1162 CPQG 1165
Score = 140 bits (339), Expect = 3e-33
Identities = 73/188 (38%), Positives = 98/188 (52%), Gaps = 8/188 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPPCDQLCHNTDGSYDC-LCRTGYELDE 182
N GSFRC C GY +G + DECA R LC NT+GS+ C C GY ++E
Sbjct: 1027 NLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNE 1086
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECS-CEDGYEKR--GDACVDINECHEEGVCP 353
DG C D+DEC +C+NT GS+ C C+ GY GD+C D++EC +
Sbjct: 1087 DGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSC 1146
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC--QAPCRNYAGGYRCDCPV 527
G C N +GS++C+CP+G++L A G C D +EC C C N G + C C
Sbjct: 1147 LGGECKNTVGSYQCLCPQGFQL-ANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAP 1205
Query: 528 GTVRSPSG 551
G V + G
Sbjct: 1206 GFVSAEGG 1213
Score = 138 bits (334), Expect = 1e-32
Identities = 72/181 (39%), Positives = 97/181 (53%), Gaps = 10/181 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+N+ GSF C+C PG+ A G + DECA P C NT+GS++CLC TG++
Sbjct: 1193 LNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSP 1252
Query: 183 DGANCRDVDECER--DTHTCQQICSNTEGSYEC--SCEDGYEK--RGDACVDINECHEEG 344
+ C D+DECE D C N+ GSY C C+ G+ GD C+DI+EC +
Sbjct: 1253 ESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGD-CIDIDECANDT 1311
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQAP-CRNYAGGYRCD 518
+C S G C N GSFRC+C +G+ + G CVD +EC C A C N G + C
Sbjct: 1312 MCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCL 1371
Query: 519 C 521
C
Sbjct: 1372 C 1372
Score = 129 bits (312), Expect = 6e-30
Identities = 74/190 (38%), Positives = 100/190 (52%), Gaps = 10/190 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA-GRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDED 185
NT+GS++C+C G++ A G +EC C N+ GS+ CLC G+ E
Sbjct: 1153 NTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEG 1212
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEG--VCP 353
G +C+DVDEC C NTEGS+ C CE G++ ++ CVDI+EC + G VC
Sbjct: 1213 GTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVC- 1271
Query: 354 SPGRCVNLLGSFRCV--CPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRCDC 521
+C N GS+RCV C G+ + A C+D DECA C + C N G +RC C
Sbjct: 1272 GTWKCENSPGSYRCVLGCQPGFHM-APNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLC 1330
Query: 522 PVGTVRSPSG 551
G SPSG
Sbjct: 1331 DQGFEISPSG 1340
Score = 106 bits (254), Expect = 6e-23
Identities = 60/149 (40%), Positives = 71/149 (47%), Gaps = 6/149 (4%)
Frame = +3
Query: 123 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY--- 293
C N Y C+C GY+L A C D +EC RD + C N GSY C C GY
Sbjct: 861 CVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCINRVGSYSCFCYPGYTLA 920
Query: 294 -EKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG 470
C DINEC + GVC S G+C N GS+ C C +GY + +G C D +EC G
Sbjct: 921 TSGATQECQDINECEQPGVC-SGGQCTNTEGSYHCECDQGYIMVRKG-HCQDINECRHPG 978
Query: 471 RC-QAPCRNYAGGYRC-DCPVGTVRSPSG 551
C C N G Y C C G R SG
Sbjct: 979 TCPDGRCVNSPGSYTCLACEEG-YRGQSG 1006
Score = 78.6 bits (185), Expect = 1e-14
Identities = 43/102 (42%), Positives = 54/102 (52%), Gaps = 6/102 (5%)
Frame = +3
Query: 12 NTIGSFRCV--CGPGYRPAGRG-VRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYEL 176
N+ GS+RCV C PG+ A G DECA C C NTDGS+ CLC G+E+
Sbjct: 1278 NSPGSYRCVLGCQPGFHMAPNGDCIDIDECA-NDTMCGSHGFCDNTDGSFRCLCDQGFEI 1336
Query: 177 DEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYEK 299
G +C DV+ECE C +C N EGS+ C C E+
Sbjct: 1337 SPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEE 1378
Score = 60.1 bits (139), Expect = 5e-09
Identities = 37/140 (26%), Positives = 54/140 (38%), Gaps = 2/140 (1%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCED 287
PC + +C C G + C D E +IC + +G E
Sbjct: 1422 PCSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSAE-----FSEICPSGKGYIPV--EG 1474
Query: 288 GYEKRGDACVDINEC--HEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA 461
+ D +EC G+CP+ GRC+N + + C+C G+ DA +C D DEC
Sbjct: 1475 AWTFGQTMYTDADECVIFGPGLCPN-GRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQ 1533
Query: 462 QTGRCQAPCRNYAGGYRCDC 521
C N G + C C
Sbjct: 1534 DLACENGECVNTEGSFHCFC 1553
Score = 57.2 bits (132), Expect = 4e-08
Identities = 29/70 (41%), Positives = 36/70 (51%), Gaps = 1/70 (1%)
Frame = +3
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG-RCQAPCRNYAGGYRCDC 521
VC PG CVNL +RCVC GY+L A C D +EC + + + C N G Y C C
Sbjct: 855 VC-GPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCINRVGSYSCFC 913
Query: 522 PVGTVRSPSG 551
G + SG
Sbjct: 914 YPGYTLATSG 923
Score = 52.4 bits (120), Expect = 1e-06
Identities = 59/202 (29%), Positives = 77/202 (38%), Gaps = 29/202 (14%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGY-ELD 179
NT GSFRC+C G+ P+G +EC + C LC N +GS+ CLC + E D
Sbjct: 1321 NTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYD 1380
Query: 180 EDGANCR-------DVDECERDTH----TCQQICSNTEGSYECSCEDGYE-KRGDACVDI 323
+CR + E H T S +G CS G + + C
Sbjct: 1381 AQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQ 1440
Query: 324 NECHEEG--VCPSPGRCVNLLGSFRCVCP--RGYRLDAEGA------RCVDRDECAQTGR 473
+ +CPS F +CP +GY + EGA D DEC G
Sbjct: 1441 GASWGDACDLCPSEDS-----AEFSEICPSGKGY-IPVEGAWTFGQTMYTDADECVIFGP 1494
Query: 474 CQAP---CRNYAGGYRCDCPVG 530
P C N GY C C G
Sbjct: 1495 GLCPNGRCLNTVPGYVCLCNPG 1516
Score = 50.4 bits (115), Expect = 4e-06
Identities = 30/87 (34%), Positives = 38/87 (43%), Gaps = 1/87 (1%)
Frame = +3
Query: 270 ECSCEDGYEKRG-DACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
+ C GY++ C DINEC G+C CVN GS+ C C G LD +RCV
Sbjct: 605 QLECPQGYKRLNLTHCQDINECLTLGLCKD-AECVNTRGSYLCTCRPGLMLDPSRSRCVS 663
Query: 447 RDECAQTGRCQAPCRNYAGGYRCDCPV 527
D+ Q C G C P+
Sbjct: 664 -DKA--ISMLQGLCYRSLGPGTCTLPL 687
Score = 50.4 bits (115), Expect = 4e-06
Identities = 29/83 (34%), Positives = 36/83 (43%), Gaps = 4/83 (4%)
Frame = +3
Query: 57 PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECER---DT 227
PAG +EC + + C Y C C G++LD C DV+EC+
Sbjct: 1726 PAGFEGLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPA 1785
Query: 228 HTCQQ-ICSNTEGSYECSCEDGY 293
C C NTEGSY C C GY
Sbjct: 1786 VLCVHGYCENTEGSYRCHCSPGY 1808
Score = 48.8 bits (111), Expect = 1e-05
Identities = 26/69 (37%), Positives = 33/69 (47%), Gaps = 2/69 (2%)
Frame = +3
Query: 246 CSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRL 419
C NT Y C C G Y+ C D +EC ++ C + G CVN GSF C C L
Sbjct: 1502 CLNTVPGYVCLCNPGFHYDASHKKCEDHDEC-QDLACEN-GECVNTEGSFHCFCSPPLTL 1559
Query: 420 DAEGARCVD 446
D RC++
Sbjct: 1560 DLSQQRCMN 1568
Score = 48.8 bits (111), Expect = 1e-05
Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 5/74 (6%)
Frame = +3
Query: 246 CSNTEGSYECSCEDGYEKRGD--ACVDINECHE---EGVCPSPGRCVNLLGSFRCVCPRG 410
C Y C C +G++ ACVD+NEC + V G C N GS+RC C G
Sbjct: 1748 CVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPG 1807
Query: 411 YRLDAEGARCVDRD 452
Y +A C ++
Sbjct: 1808 YVAEAGPPHCTAKE 1821
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/75 (37%), Positives = 34/75 (45%), Gaps = 5/75 (6%)
Frame = +3
Query: 327 ECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG----RC-QAPCR 491
EC C + GRCV + + C C G++LDA CVD +EC C C
Sbjct: 1736 ECGILNGCEN-GRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCE 1794
Query: 492 NYAGGYRCDCPVGTV 536
N G YRC C G V
Sbjct: 1795 NTEGSYRCHCSPGYV 1809
Score = 41.9 bits (94), Expect = 0.001
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 4/85 (4%)
Frame = +3
Query: 306 DACVDINECHEEGVC-PSPGRCVN-LLGSFRCVCPRGY-RLDAEGARCVDRDECAQTGRC 476
D C + +C P P R + ++ + + CP+GY RL+ C D +EC G C
Sbjct: 575 DCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQGYKRLNL--THCQDINECLTLGLC 632
Query: 477 Q-APCRNYAGGYRCDCPVGTVRSPS 548
+ A C N G Y C C G + PS
Sbjct: 633 KDAECVNTRGSYLCTCRPGLMLDPS 657
Score = 41.1 bits (92), Expect = 0.003
Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 3/77 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPG--YRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYE 173
R +NT+ + C+C PG Y + + DEC + C+ C NT+GS+ C C
Sbjct: 1501 RCLNTVPGYVCLCNPGFHYDASHKKCEDHDEC--QDLACENGECVNTEGSFHCFCSPPLT 1558
Query: 174 LDEDGANCRDVDECERD 224
LD C + D
Sbjct: 1559 LDLSQQRCMNSTSSTED 1575
Score = 37.1 bits (82), Expect = 0.041
Identities = 32/114 (28%), Positives = 45/114 (39%), Gaps = 4/114 (3%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEG 263
+EC D C NT GSY C CR G LD + C ++ Q +C + G
Sbjct: 624 NECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRC----VSDKAISMLQGLCYRSLG 679
Query: 264 SYECS--CEDGYEKRGDACVDINEC--HEEGVCPSPGRCVNLLGSFRCVCPRGY 413
C+ K+ C + + E CP PG +FR +CP G+
Sbjct: 680 PGTCTLPLAQRITKQICCCSRVGKAWGSECEKCPLPG-----TEAFREICPAGH 728
Score = 31.1 bits (67), Expect = 2.7
Identities = 11/25 (44%), Positives = 14/25 (56%)
Frame = +3
Query: 123 CHNTDGSYDCLCRTGYELDEDGANC 197
C NT+GSY C C GY + +C
Sbjct: 1793 CENTEGSYRCHCSPGYVAEAGPPHC 1817
>BC078659-1|AAH78659.1| 1821|Homo sapiens latent transforming growth
factor beta binding protein 2 protein.
Length = 1821
Score = 145 bits (352), Expect = 8e-35
Identities = 77/181 (42%), Positives = 92/181 (50%), Gaps = 7/181 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN +RCVC PGY+ P+ +EC P C N GSY C C GY L
Sbjct: 862 VNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCINRVGSYSCFCYPGYTLAT 921
Query: 183 DGA--NCRDVDECERDTHTCQQICSNTEGSYECSCEDGY-EKRGDACVDINECHEEGVCP 353
GA C+D++ECE+ C+NTEGSY C C+ GY R C DINEC G CP
Sbjct: 922 SGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKGHCQDINECRHPGTCP 981
Query: 354 SPGRCVNLLGSFRCV-CPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPV 527
GRCVN GS+ C+ C GYR + CVD +EC G C C N G +RC C
Sbjct: 982 D-GRCVNSPGSYTCLACEEGYR--GQSGSCVDVNECLTPGVCAHGKCTNLEGSFRCSCEQ 1038
Query: 528 G 530
G
Sbjct: 1039 G 1039
Score = 142 bits (344), Expect = 7e-34
Identities = 75/179 (41%), Positives = 100/179 (55%), Gaps = 8/179 (4%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGV----RGRDECAVRPPPCD-QLCHNTDGSYDCLCRTG 167
R +N +GS+ C C PGY A G + +EC +P C C NT+GSY C C G
Sbjct: 901 RCINRVGSYSCFCYPGYTLATSGATQECQDINECE-QPGVCSGGQCTNTEGSYHCECDQG 959
Query: 168 YELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYEC-SCEDGYEKRGDACVDINECHEE 341
Y + G +C+D++EC R TC C N+ GSY C +CE+GY + +CVD+NEC
Sbjct: 960 YIMVRKG-HCQDINEC-RHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTP 1017
Query: 342 GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP-CRNYAGGYRC 515
GVC + G+C NL GSFRC C +GY + ++ C D DECA C C N G + C
Sbjct: 1018 GVC-AHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFAC 1075
Score = 142 bits (343), Expect = 1e-33
Identities = 79/184 (42%), Positives = 97/184 (52%), Gaps = 8/184 (4%)
Frame = +3
Query: 3 RGVNTIGSFRCV-CGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYEL 176
R VN+ GS+ C+ C GYR +EC + P C C N +GS+ C C GYE+
Sbjct: 984 RCVNSPGSYTCLACEEGYRGQSGSCVDVNEC-LTPGVCAHGKCTNLEGSFRCSCEQGYEV 1042
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECS-CEDGY--EKRGDACVDINECHEEGV 347
D C+DVDEC +C NTEGS+ CS CE+GY + G AC D++EC GV
Sbjct: 1043 TSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAFPGV 1102
Query: 348 CPSPGRCVNLLGSFRCV-CPRGYRLDAEGARCVDRDEC--AQTGRCQAPCRNYAGGYRCD 518
CPS G C N GSF C C GYR G C D DEC Q+ C+N G Y+C
Sbjct: 1103 CPS-GVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCL 1161
Query: 519 CPVG 530
CP G
Sbjct: 1162 CPQG 1165
Score = 140 bits (339), Expect = 3e-33
Identities = 73/188 (38%), Positives = 98/188 (52%), Gaps = 8/188 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPPCDQLCHNTDGSYDC-LCRTGYELDE 182
N GSFRC C GY +G + DECA R LC NT+GS+ C C GY ++E
Sbjct: 1027 NLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNE 1086
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECS-CEDGYEKR--GDACVDINECHEEGVCP 353
DG C D+DEC +C+NT GS+ C C+ GY GD+C D++EC +
Sbjct: 1087 DGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSC 1146
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC--QAPCRNYAGGYRCDCPV 527
G C N +GS++C+CP+G++L A G C D +EC C C N G + C C
Sbjct: 1147 LGGECKNTVGSYQCLCPQGFQL-ANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAP 1205
Query: 528 GTVRSPSG 551
G V + G
Sbjct: 1206 GFVSAEGG 1213
Score = 138 bits (334), Expect = 1e-32
Identities = 72/181 (39%), Positives = 97/181 (53%), Gaps = 10/181 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+N+ GSF C+C PG+ A G + DECA P C NT+GS++CLC TG++
Sbjct: 1193 LNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSP 1252
Query: 183 DGANCRDVDECER--DTHTCQQICSNTEGSYEC--SCEDGYEK--RGDACVDINECHEEG 344
+ C D+DECE D C N+ GSY C C+ G+ GD C+DI+EC +
Sbjct: 1253 ESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGD-CIDIDECANDT 1311
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQAP-CRNYAGGYRCD 518
+C S G C N GSFRC+C +G+ + G CVD +EC C A C N G + C
Sbjct: 1312 MCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCL 1371
Query: 519 C 521
C
Sbjct: 1372 C 1372
Score = 129 bits (312), Expect = 6e-30
Identities = 74/190 (38%), Positives = 100/190 (52%), Gaps = 10/190 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA-GRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDED 185
NT+GS++C+C G++ A G +EC C N+ GS+ CLC G+ E
Sbjct: 1153 NTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEG 1212
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEG--VCP 353
G +C+DVDEC C NTEGS+ C CE G++ ++ CVDI+EC + G VC
Sbjct: 1213 GTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVC- 1271
Query: 354 SPGRCVNLLGSFRCV--CPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRCDC 521
+C N GS+RCV C G+ + A C+D DECA C + C N G +RC C
Sbjct: 1272 GTWKCENSPGSYRCVLGCQPGFHM-APNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLC 1330
Query: 522 PVGTVRSPSG 551
G SPSG
Sbjct: 1331 DQGFEISPSG 1340
Score = 106 bits (254), Expect = 6e-23
Identities = 60/149 (40%), Positives = 71/149 (47%), Gaps = 6/149 (4%)
Frame = +3
Query: 123 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY--- 293
C N Y C+C GY+L A C D +EC RD + C N GSY C C GY
Sbjct: 861 CVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCINRVGSYSCFCYPGYTLA 920
Query: 294 -EKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG 470
C DINEC + GVC S G+C N GS+ C C +GY + +G C D +EC G
Sbjct: 921 TSGATQECQDINECEQPGVC-SGGQCTNTEGSYHCECDQGYIMVRKG-HCQDINECRHPG 978
Query: 471 RC-QAPCRNYAGGYRC-DCPVGTVRSPSG 551
C C N G Y C C G R SG
Sbjct: 979 TCPDGRCVNSPGSYTCLACEEG-YRGQSG 1006
Score = 78.6 bits (185), Expect = 1e-14
Identities = 43/102 (42%), Positives = 54/102 (52%), Gaps = 6/102 (5%)
Frame = +3
Query: 12 NTIGSFRCV--CGPGYRPAGRG-VRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYEL 176
N+ GS+RCV C PG+ A G DECA C C NTDGS+ CLC G+E+
Sbjct: 1278 NSPGSYRCVLGCQPGFHMAPNGDCIDIDECA-NDTMCGSHGFCDNTDGSFRCLCDQGFEI 1336
Query: 177 DEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYEK 299
G +C DV+ECE C +C N EGS+ C C E+
Sbjct: 1337 SPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEE 1378
Score = 60.1 bits (139), Expect = 5e-09
Identities = 37/140 (26%), Positives = 54/140 (38%), Gaps = 2/140 (1%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCED 287
PC + +C C G + C D E +IC + +G E
Sbjct: 1422 PCSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSAE-----FSEICPSGKGYIPV--EG 1474
Query: 288 GYEKRGDACVDINEC--HEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA 461
+ D +EC G+CP+ GRC+N + + C+C G+ DA +C D DEC
Sbjct: 1475 AWTFGQTMYTDADECVIFGPGLCPN-GRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQ 1533
Query: 462 QTGRCQAPCRNYAGGYRCDC 521
C N G + C C
Sbjct: 1534 DLACENGECVNTEGSFHCFC 1553
Score = 57.2 bits (132), Expect = 4e-08
Identities = 29/70 (41%), Positives = 36/70 (51%), Gaps = 1/70 (1%)
Frame = +3
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG-RCQAPCRNYAGGYRCDC 521
VC PG CVNL +RCVC GY+L A C D +EC + + + C N G Y C C
Sbjct: 855 VC-GPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCINRVGSYSCFC 913
Query: 522 PVGTVRSPSG 551
G + SG
Sbjct: 914 YPGYTLATSG 923
Score = 52.4 bits (120), Expect = 1e-06
Identities = 59/202 (29%), Positives = 77/202 (38%), Gaps = 29/202 (14%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGY-ELD 179
NT GSFRC+C G+ P+G +EC + C LC N +GS+ CLC + E D
Sbjct: 1321 NTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYD 1380
Query: 180 EDGANCR-------DVDECERDTH----TCQQICSNTEGSYECSCEDGYE-KRGDACVDI 323
+CR + E H T S +G CS G + + C
Sbjct: 1381 AQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQ 1440
Query: 324 NECHEEG--VCPSPGRCVNLLGSFRCVCP--RGYRLDAEGA------RCVDRDECAQTGR 473
+ +CPS F +CP +GY + EGA D DEC G
Sbjct: 1441 GASWGDACDLCPSEDS-----AEFSEICPSGKGY-IPVEGAWTFGQTMYTDADECVIFGP 1494
Query: 474 CQAP---CRNYAGGYRCDCPVG 530
P C N GY C C G
Sbjct: 1495 GLCPNGRCLNTVPGYVCLCNPG 1516
Score = 50.4 bits (115), Expect = 4e-06
Identities = 30/87 (34%), Positives = 38/87 (43%), Gaps = 1/87 (1%)
Frame = +3
Query: 270 ECSCEDGYEKRG-DACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
+ C GY++ C DINEC G+C CVN GS+ C C G LD +RCV
Sbjct: 605 QLECPQGYKRLNLTHCQDINECLTLGLCKD-AECVNTRGSYLCTCRPGLMLDPSRSRCVS 663
Query: 447 RDECAQTGRCQAPCRNYAGGYRCDCPV 527
D+ Q C G C P+
Sbjct: 664 -DKA--ISMLQGLCYRSLGPGTCTLPL 687
Score = 50.4 bits (115), Expect = 4e-06
Identities = 29/83 (34%), Positives = 36/83 (43%), Gaps = 4/83 (4%)
Frame = +3
Query: 57 PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECER---DT 227
PAG +EC + + C Y C C G++LD C DV+EC+
Sbjct: 1726 PAGFEGLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPA 1785
Query: 228 HTCQQ-ICSNTEGSYECSCEDGY 293
C C NTEGSY C C GY
Sbjct: 1786 VLCVHGYCENTEGSYRCHCSPGY 1808
Score = 48.8 bits (111), Expect = 1e-05
Identities = 26/69 (37%), Positives = 33/69 (47%), Gaps = 2/69 (2%)
Frame = +3
Query: 246 CSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRL 419
C NT Y C C G Y+ C D +EC ++ C + G CVN GSF C C L
Sbjct: 1502 CLNTVPGYVCLCNPGFHYDASHKKCEDHDEC-QDLACEN-GECVNTEGSFHCFCSPPLTL 1559
Query: 420 DAEGARCVD 446
D RC++
Sbjct: 1560 DLSQQRCMN 1568
Score = 48.8 bits (111), Expect = 1e-05
Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 5/74 (6%)
Frame = +3
Query: 246 CSNTEGSYECSCEDGYEKRGD--ACVDINECHE---EGVCPSPGRCVNLLGSFRCVCPRG 410
C Y C C +G++ ACVD+NEC + V G C N GS+RC C G
Sbjct: 1748 CVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPG 1807
Query: 411 YRLDAEGARCVDRD 452
Y +A C ++
Sbjct: 1808 YVAEAGPPHCTAKE 1821
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/75 (37%), Positives = 34/75 (45%), Gaps = 5/75 (6%)
Frame = +3
Query: 327 ECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG----RC-QAPCR 491
EC C + GRCV + + C C G++LDA CVD +EC C C
Sbjct: 1736 ECGILNGCEN-GRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCE 1794
Query: 492 NYAGGYRCDCPVGTV 536
N G YRC C G V
Sbjct: 1795 NTEGSYRCHCSPGYV 1809
Score = 41.9 bits (94), Expect = 0.001
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 4/85 (4%)
Frame = +3
Query: 306 DACVDINECHEEGVC-PSPGRCVN-LLGSFRCVCPRGY-RLDAEGARCVDRDECAQTGRC 476
D C + +C P P R + ++ + + CP+GY RL+ C D +EC G C
Sbjct: 575 DCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQGYKRLNL--THCQDINECLTLGLC 632
Query: 477 Q-APCRNYAGGYRCDCPVGTVRSPS 548
+ A C N G Y C C G + PS
Sbjct: 633 KDAECVNTRGSYLCTCRPGLMLDPS 657
Score = 41.1 bits (92), Expect = 0.003
Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 3/77 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPG--YRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYE 173
R +NT+ + C+C PG Y + + DEC + C+ C NT+GS+ C C
Sbjct: 1501 RCLNTVPGYVCLCNPGFHYDASHKKCEDHDEC--QDLACENGECVNTEGSFHCFCSPPLT 1558
Query: 174 LDEDGANCRDVDECERD 224
LD C + D
Sbjct: 1559 LDLSQQRCMNSTSSTED 1575
Score = 37.1 bits (82), Expect = 0.041
Identities = 32/114 (28%), Positives = 45/114 (39%), Gaps = 4/114 (3%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEG 263
+EC D C NT GSY C CR G LD + C ++ Q +C + G
Sbjct: 624 NECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRC----VSDKAISMLQGLCYRSLG 679
Query: 264 SYECS--CEDGYEKRGDACVDINEC--HEEGVCPSPGRCVNLLGSFRCVCPRGY 413
C+ K+ C + + E CP PG +FR +CP G+
Sbjct: 680 PGTCTLPLAQRITKQICCCSRVGKAWGSECEKCPLPG-----TEAFREICPAGH 728
Score = 31.1 bits (67), Expect = 2.7
Identities = 11/25 (44%), Positives = 14/25 (56%)
Frame = +3
Query: 123 CHNTDGSYDCLCRTGYELDEDGANC 197
C NT+GSY C C GY + +C
Sbjct: 1793 CENTEGSYRCHCSPGYVAEAGPPHC 1817
>AB209865-1|BAD93102.1| 1700|Homo sapiens latent transforming growth
factor beta binding protein 2 variant protein.
Length = 1700
Score = 145 bits (352), Expect = 8e-35
Identities = 77/181 (42%), Positives = 92/181 (50%), Gaps = 7/181 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN +RCVC PGY+ P+ +EC P C N GSY C C GY L
Sbjct: 741 VNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCINRVGSYSCFCYPGYTLAT 800
Query: 183 DGA--NCRDVDECERDTHTCQQICSNTEGSYECSCEDGY-EKRGDACVDINECHEEGVCP 353
GA C+D++ECE+ C+NTEGSY C C+ GY R C DINEC G CP
Sbjct: 801 SGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKGHCQDINECRHPGTCP 860
Query: 354 SPGRCVNLLGSFRCV-CPRGYRLDAEGARCVDRDECAQTGRC-QAPCRNYAGGYRCDCPV 527
GRCVN GS+ C+ C GYR + CVD +EC G C C N G +RC C
Sbjct: 861 D-GRCVNSPGSYTCLACEEGYR--GQSGSCVDVNECLTPGVCAHGKCTNLEGSFRCSCEQ 917
Query: 528 G 530
G
Sbjct: 918 G 918
Score = 142 bits (344), Expect = 7e-34
Identities = 75/179 (41%), Positives = 100/179 (55%), Gaps = 8/179 (4%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGV----RGRDECAVRPPPCD-QLCHNTDGSYDCLCRTG 167
R +N +GS+ C C PGY A G + +EC +P C C NT+GSY C C G
Sbjct: 780 RCINRVGSYSCFCYPGYTLATSGATQECQDINECE-QPGVCSGGQCTNTEGSYHCECDQG 838
Query: 168 YELDEDGANCRDVDECERDTHTCQQ-ICSNTEGSYEC-SCEDGYEKRGDACVDINECHEE 341
Y + G +C+D++EC R TC C N+ GSY C +CE+GY + +CVD+NEC
Sbjct: 839 YIMVRKG-HCQDINEC-RHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTP 896
Query: 342 GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP-CRNYAGGYRC 515
GVC + G+C NL GSFRC C +GY + ++ C D DECA C C N G + C
Sbjct: 897 GVC-AHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFAC 954
Score = 142 bits (343), Expect = 1e-33
Identities = 79/184 (42%), Positives = 97/184 (52%), Gaps = 8/184 (4%)
Frame = +3
Query: 3 RGVNTIGSFRCV-CGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYEL 176
R VN+ GS+ C+ C GYR +EC + P C C N +GS+ C C GYE+
Sbjct: 863 RCVNSPGSYTCLACEEGYRGQSGSCVDVNEC-LTPGVCAHGKCTNLEGSFRCSCEQGYEV 921
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECS-CEDGY--EKRGDACVDINECHEEGV 347
D C+DVDEC +C NTEGS+ CS CE+GY + G AC D++EC GV
Sbjct: 922 TSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAFPGV 981
Query: 348 CPSPGRCVNLLGSFRCV-CPRGYRLDAEGARCVDRDEC--AQTGRCQAPCRNYAGGYRCD 518
CPS G C N GSF C C GYR G C D DEC Q+ C+N G Y+C
Sbjct: 982 CPS-GVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCL 1040
Query: 519 CPVG 530
CP G
Sbjct: 1041 CPQG 1044
Score = 140 bits (339), Expect = 3e-33
Identities = 73/188 (38%), Positives = 98/188 (52%), Gaps = 8/188 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPPCDQLCHNTDGSYDC-LCRTGYELDE 182
N GSFRC C GY +G + DECA R LC NT+GS+ C C GY ++E
Sbjct: 906 NLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNE 965
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECS-CEDGYEKR--GDACVDINECHEEGVCP 353
DG C D+DEC +C+NT GS+ C C+ GY GD+C D++EC +
Sbjct: 966 DGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSC 1025
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC--QAPCRNYAGGYRCDCPV 527
G C N +GS++C+CP+G++L A G C D +EC C C N G + C C
Sbjct: 1026 LGGECKNTVGSYQCLCPQGFQL-ANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAP 1084
Query: 528 GTVRSPSG 551
G V + G
Sbjct: 1085 GFVSAEGG 1092
Score = 138 bits (334), Expect = 1e-32
Identities = 72/181 (39%), Positives = 97/181 (53%), Gaps = 10/181 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+N+ GSF C+C PG+ A G + DECA P C NT+GS++CLC TG++
Sbjct: 1072 LNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSP 1131
Query: 183 DGANCRDVDECER--DTHTCQQICSNTEGSYEC--SCEDGYEK--RGDACVDINECHEEG 344
+ C D+DECE D C N+ GSY C C+ G+ GD C+DI+EC +
Sbjct: 1132 ESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGD-CIDIDECANDT 1190
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQAP-CRNYAGGYRCD 518
+C S G C N GSFRC+C +G+ + G CVD +EC C A C N G + C
Sbjct: 1191 MCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCL 1250
Query: 519 C 521
C
Sbjct: 1251 C 1251
Score = 129 bits (312), Expect = 6e-30
Identities = 74/190 (38%), Positives = 100/190 (52%), Gaps = 10/190 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA-GRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDED 185
NT+GS++C+C G++ A G +EC C N+ GS+ CLC G+ E
Sbjct: 1032 NTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEG 1091
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEG--VCP 353
G +C+DVDEC C NTEGS+ C CE G++ ++ CVDI+EC + G VC
Sbjct: 1092 GTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVC- 1150
Query: 354 SPGRCVNLLGSFRCV--CPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRCDC 521
+C N GS+RCV C G+ + A C+D DECA C + C N G +RC C
Sbjct: 1151 GTWKCENSPGSYRCVLGCQPGFHM-APNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLC 1209
Query: 522 PVGTVRSPSG 551
G SPSG
Sbjct: 1210 DQGFEISPSG 1219
Score = 106 bits (254), Expect = 6e-23
Identities = 60/149 (40%), Positives = 71/149 (47%), Gaps = 6/149 (4%)
Frame = +3
Query: 123 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY--- 293
C N Y C+C GY+L A C D +EC RD + C N GSY C C GY
Sbjct: 740 CVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCINRVGSYSCFCYPGYTLA 799
Query: 294 -EKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG 470
C DINEC + GVC S G+C N GS+ C C +GY + +G C D +EC G
Sbjct: 800 TSGATQECQDINECEQPGVC-SGGQCTNTEGSYHCECDQGYIMVRKG-HCQDINECRHPG 857
Query: 471 RC-QAPCRNYAGGYRC-DCPVGTVRSPSG 551
C C N G Y C C G R SG
Sbjct: 858 TCPDGRCVNSPGSYTCLACEEG-YRGQSG 885
Score = 78.6 bits (185), Expect = 1e-14
Identities = 43/102 (42%), Positives = 54/102 (52%), Gaps = 6/102 (5%)
Frame = +3
Query: 12 NTIGSFRCV--CGPGYRPAGRG-VRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYEL 176
N+ GS+RCV C PG+ A G DECA C C NTDGS+ CLC G+E+
Sbjct: 1157 NSPGSYRCVLGCQPGFHMAPNGDCIDIDECA-NDTMCGSHGFCDNTDGSFRCLCDQGFEI 1215
Query: 177 DEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYEK 299
G +C DV+ECE C +C N EGS+ C C E+
Sbjct: 1216 SPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEE 1257
Score = 60.1 bits (139), Expect = 5e-09
Identities = 37/140 (26%), Positives = 54/140 (38%), Gaps = 2/140 (1%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCED 287
PC + +C C G + C D E +IC + +G E
Sbjct: 1301 PCSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSAE-----FSEICPSGKGYIPV--EG 1353
Query: 288 GYEKRGDACVDINEC--HEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA 461
+ D +EC G+CP+ GRC+N + + C+C G+ DA +C D DEC
Sbjct: 1354 AWTFGQTMYTDADECVIFGPGLCPN-GRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQ 1412
Query: 462 QTGRCQAPCRNYAGGYRCDC 521
C N G + C C
Sbjct: 1413 DLACENGECVNTEGSFHCFC 1432
Score = 57.2 bits (132), Expect = 4e-08
Identities = 29/70 (41%), Positives = 36/70 (51%), Gaps = 1/70 (1%)
Frame = +3
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG-RCQAPCRNYAGGYRCDC 521
VC PG CVNL +RCVC GY+L A C D +EC + + + C N G Y C C
Sbjct: 734 VC-GPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCINRVGSYSCFC 792
Query: 522 PVGTVRSPSG 551
G + SG
Sbjct: 793 YPGYTLATSG 802
Score = 52.4 bits (120), Expect = 1e-06
Identities = 59/202 (29%), Positives = 77/202 (38%), Gaps = 29/202 (14%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGY-ELD 179
NT GSFRC+C G+ P+G +EC + C LC N +GS+ CLC + E D
Sbjct: 1200 NTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYD 1259
Query: 180 EDGANCR-------DVDECERDTH----TCQQICSNTEGSYECSCEDGYE-KRGDACVDI 323
+CR + E H T S +G CS G + + C
Sbjct: 1260 AQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQ 1319
Query: 324 NECHEEG--VCPSPGRCVNLLGSFRCVCP--RGYRLDAEGA------RCVDRDECAQTGR 473
+ +CPS F +CP +GY + EGA D DEC G
Sbjct: 1320 GASWGDACDLCPSEDS-----AEFSEICPSGKGY-IPVEGAWTFGQTMYTDADECVIFGP 1373
Query: 474 CQAP---CRNYAGGYRCDCPVG 530
P C N GY C C G
Sbjct: 1374 GLCPNGRCLNTVPGYVCLCNPG 1395
Score = 50.4 bits (115), Expect = 4e-06
Identities = 30/87 (34%), Positives = 38/87 (43%), Gaps = 1/87 (1%)
Frame = +3
Query: 270 ECSCEDGYEKRG-DACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
+ C GY++ C DINEC G+C CVN GS+ C C G LD +RCV
Sbjct: 484 QLECPQGYKRLNLTHCQDINECLTLGLCKD-AECVNTRGSYLCTCRPGLMLDPSRSRCVS 542
Query: 447 RDECAQTGRCQAPCRNYAGGYRCDCPV 527
D+ Q C G C P+
Sbjct: 543 -DKA--ISMLQGLCYRSLGPGTCTLPL 566
Score = 50.4 bits (115), Expect = 4e-06
Identities = 29/83 (34%), Positives = 36/83 (43%), Gaps = 4/83 (4%)
Frame = +3
Query: 57 PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECER---DT 227
PAG +EC + + C Y C C G++LD C DV+EC+
Sbjct: 1605 PAGFEGLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPA 1664
Query: 228 HTCQQ-ICSNTEGSYECSCEDGY 293
C C NTEGSY C C GY
Sbjct: 1665 VLCVHGYCENTEGSYRCHCSPGY 1687
Score = 48.8 bits (111), Expect = 1e-05
Identities = 26/69 (37%), Positives = 33/69 (47%), Gaps = 2/69 (2%)
Frame = +3
Query: 246 CSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRL 419
C NT Y C C G Y+ C D +EC ++ C + G CVN GSF C C L
Sbjct: 1381 CLNTVPGYVCLCNPGFHYDASHKKCEDHDEC-QDLACEN-GECVNTEGSFHCFCSPPLTL 1438
Query: 420 DAEGARCVD 446
D RC++
Sbjct: 1439 DLSQQRCMN 1447
Score = 48.8 bits (111), Expect = 1e-05
Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 5/74 (6%)
Frame = +3
Query: 246 CSNTEGSYECSCEDGYEKRGD--ACVDINECHE---EGVCPSPGRCVNLLGSFRCVCPRG 410
C Y C C +G++ ACVD+NEC + V G C N GS+RC C G
Sbjct: 1627 CVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPG 1686
Query: 411 YRLDAEGARCVDRD 452
Y +A C ++
Sbjct: 1687 YVAEAGPPHCTAKE 1700
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/75 (37%), Positives = 34/75 (45%), Gaps = 5/75 (6%)
Frame = +3
Query: 327 ECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG----RC-QAPCR 491
EC C + GRCV + + C C G++LDA CVD +EC C C
Sbjct: 1615 ECGILNGCEN-GRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCE 1673
Query: 492 NYAGGYRCDCPVGTV 536
N G YRC C G V
Sbjct: 1674 NTEGSYRCHCSPGYV 1688
Score = 41.9 bits (94), Expect = 0.001
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 4/85 (4%)
Frame = +3
Query: 306 DACVDINECHEEGVC-PSPGRCVN-LLGSFRCVCPRGY-RLDAEGARCVDRDECAQTGRC 476
D C + +C P P R + ++ + + CP+GY RL+ C D +EC G C
Sbjct: 454 DCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQGYKRLNL--THCQDINECLTLGLC 511
Query: 477 Q-APCRNYAGGYRCDCPVGTVRSPS 548
+ A C N G Y C C G + PS
Sbjct: 512 KDAECVNTRGSYLCTCRPGLMLDPS 536
Score = 41.1 bits (92), Expect = 0.003
Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 3/77 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPG--YRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYE 173
R +NT+ + C+C PG Y + + DEC + C+ C NT+GS+ C C
Sbjct: 1380 RCLNTVPGYVCLCNPGFHYDASHKKCEDHDEC--QDLACENGECVNTEGSFHCFCSPPLT 1437
Query: 174 LDEDGANCRDVDECERD 224
LD C + D
Sbjct: 1438 LDLSQQRCMNSTSSTED 1454
Score = 37.1 bits (82), Expect = 0.041
Identities = 32/114 (28%), Positives = 45/114 (39%), Gaps = 4/114 (3%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEG 263
+EC D C NT GSY C CR G LD + C ++ Q +C + G
Sbjct: 503 NECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRC----VSDKAISMLQGLCYRSLG 558
Query: 264 SYECS--CEDGYEKRGDACVDINEC--HEEGVCPSPGRCVNLLGSFRCVCPRGY 413
C+ K+ C + + E CP PG +FR +CP G+
Sbjct: 559 PGTCTLPLAQRITKQICCCSRVGKAWGSECEKCPLPG-----TEAFREICPAGH 607
Score = 31.1 bits (67), Expect = 2.7
Identities = 11/25 (44%), Positives = 14/25 (56%)
Frame = +3
Query: 123 CHNTDGSYDCLCRTGYELDEDGANC 197
C NT+GSY C C GY + +C
Sbjct: 1672 CENTEGSYRCHCSPGYVAEAGPPHC 1696
>X82494-1|CAA57876.1| 1184|Homo sapiens fibulin-2 protein.
Length = 1184
Score = 144 bits (349), Expect = 2e-34
Identities = 79/188 (42%), Positives = 100/188 (53%), Gaps = 12/188 (6%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY-RPA-GRGVRGRDECAVRPPP-CDQLCHNTDGSYDCLCRTGYELDE 182
N GS+RC C G+ R A GRG +EC P C C NT GSY C C +G+ L
Sbjct: 877 NLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAA 936
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPS 356
DG C DV+ECE C Q C+N GSY+C C GY+ + G C DI+EC +
Sbjct: 937 DGKRCEDVNECE--AQRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILC 994
Query: 357 PGRCVNLLGSFRCVCP-RGYRLDAEGARCVDRDECA-QTGRCQ--APCRNYAGGYRC--- 515
RC+N+ GS++C CP +GY + A G C D DECA T C C N G +RC
Sbjct: 995 TFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRF 1054
Query: 516 DCPVGTVR 539
+CP V+
Sbjct: 1055 ECPPNYVQ 1062
Score = 143 bits (347), Expect = 3e-34
Identities = 75/186 (40%), Positives = 95/186 (51%), Gaps = 14/186 (7%)
Frame = +3
Query: 9 VNTIGSFRC-----VCGPGYRPAGRGVRGRD--ECAVRPPPCD--QLCHNTDGSYDCLCR 161
+NT+GS+ C +C GY + G + D EC C Q+CHN GSY C C+
Sbjct: 828 INTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCK 887
Query: 162 TGYELDEDGANCRDVDEC-ERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINEC 332
G++ D G C DV+EC CQ C NT GSY CSC G+ G C D+NEC
Sbjct: 888 AGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNEC 947
Query: 333 HEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG--RCQAPCRNYAGG 506
E C C N+ GS++C C +GY+L +G C D DECAQ C C N G
Sbjct: 948 -EAQRCSQ--ECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGS 1004
Query: 507 YRCDCP 524
Y+C CP
Sbjct: 1005 YQCACP 1010
Score = 134 bits (323), Expect = 3e-31
Identities = 84/204 (41%), Positives = 101/204 (49%), Gaps = 23/204 (11%)
Frame = +3
Query: 9 VNTIGSFRC----VCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCL----C 158
VNT+GSF C C PGY DECA+ C LC NT GS+ C C
Sbjct: 737 VNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRC 796
Query: 159 RTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECS-----CEDGYEKRGDA-- 311
G+ D +G NC D++EC + C+ C NT GSY C C GY D
Sbjct: 797 MDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGAK 855
Query: 312 CVDINECHEEGV--CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGR-CQ 479
CVD+NEC E GV C C NL GS+RC C G++ DA G C+D +EC A GR CQ
Sbjct: 856 CVDVNEC-ETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQ 914
Query: 480 APCRNYAGGYRCDCPVGTVRSPSG 551
C N G YRC C G + + G
Sbjct: 915 HTCENTLGSYRCSCASGFLLAADG 938
Score = 119 bits (287), Expect = 6e-27
Identities = 67/169 (39%), Positives = 84/169 (49%), Gaps = 9/169 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
NT+GS+RC C G+ A G R D C Q C N GSY C CR GY+L EDG
Sbjct: 919 NTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQCYCRQGYQLAEDGH 978
Query: 192 NCRDVDECERDTH-TCQQICSNTEGSYECSC-EDGY--EKRGDACVDINECH-EEGVCPS 356
C D+DEC + C C N GSY+C+C E GY G +C D++EC C
Sbjct: 979 TCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSE 1038
Query: 357 PGRCVNLLGSFRCV---CPRGYRLDAEGARCVDRDECAQTGRCQ-APCR 491
C N+ GSFRC+ CP Y + +C +R C CQ +P R
Sbjct: 1039 AETCHNIQGSFRCLRFECPPNY-VQVSKTKC-ERTTCHDFLECQNSPAR 1085
Score = 102 bits (245), Expect = 7e-22
Identities = 58/150 (38%), Positives = 71/150 (47%), Gaps = 14/150 (9%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-- 275
PC Q+C GS C C GY + DG +C D++EC D HTC + C NT GS+ C
Sbjct: 688 PCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYK 747
Query: 276 --SCEDGYEKRGDACVDINECHEEGVCPSPG-RCVNLLGSFRCV----CPRGYRLDAEGA 434
+CE GY + C D++EC PG C N GSF C C G+ D EG
Sbjct: 748 ALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG- 806
Query: 435 RCVDRDECAQTGRCQAP---CRNYAGGYRC 515
CVD +EC P C N G Y C
Sbjct: 807 NCVDINECTSLSEPCRPGFSCINTVGSYTC 836
Score = 83.8 bits (198), Expect = 4e-16
Identities = 65/195 (33%), Positives = 81/195 (41%), Gaps = 14/195 (7%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+NT+GS+ C C PG+ G R E P Q + + L
Sbjct: 621 INTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQE-PALKSEFSQVASNTIPLPLPQ 679
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEE-GVCPSP 359
N C +D C+Q+CS GS CSC GY D +C DINEC + C
Sbjct: 680 PN-----TC-KDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRG 733
Query: 360 GRCVNLLGSFRC----VCPRGYRLDAEGARCVDRDECAQ-TGRCQAP--CRNYAGGYRCD 518
CVN LGSF C C GY L + C D DECA T CQ C+N G + C
Sbjct: 734 EHCVNTLGSFHCYKALTCEPGYAL--KDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQ 791
Query: 519 ----CPVGTVRSPSG 551
C G ++ P G
Sbjct: 792 ARQRCMDGFLQDPEG 806
Score = 62.5 bits (145), Expect = 1e-09
Identities = 46/154 (29%), Positives = 63/154 (40%), Gaps = 9/154 (5%)
Frame = +3
Query: 81 RDECAVRPPP-CDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNT 257
+DEC + P C LC NT GSY C C G+ L +DG CR + H Q
Sbjct: 605 QDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRP------EGHPPQ-----P 653
Query: 258 EGSYECSCEDGYEKRGDACVDI-----NECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLD 422
E E + + + + + + N C + G C C + GS C C GY +
Sbjct: 654 EAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQV--CSTVGGSAICSCFPGYAIM 711
Query: 423 AEGARCVDRDECA---QTGRCQAPCRNYAGGYRC 515
A+G C D +EC T C N G + C
Sbjct: 712 ADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHC 745
>BC051690-1|AAH51690.1| 1184|Homo sapiens fibulin 2 protein.
Length = 1184
Score = 144 bits (349), Expect = 2e-34
Identities = 79/188 (42%), Positives = 100/188 (53%), Gaps = 12/188 (6%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY-RPA-GRGVRGRDECAVRPPP-CDQLCHNTDGSYDCLCRTGYELDE 182
N GS+RC C G+ R A GRG +EC P C C NT GSY C C +G+ L
Sbjct: 877 NLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAA 936
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPS 356
DG C DV+ECE C Q C+N GSY+C C GY+ + G C DI+EC +
Sbjct: 937 DGKRCEDVNECE--AQRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILC 994
Query: 357 PGRCVNLLGSFRCVCP-RGYRLDAEGARCVDRDECA-QTGRCQ--APCRNYAGGYRC--- 515
RC+N+ GS++C CP +GY + A G C D DECA T C C N G +RC
Sbjct: 995 TFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRL 1054
Query: 516 DCPVGTVR 539
+CP V+
Sbjct: 1055 ECPPNYVQ 1062
Score = 143 bits (347), Expect = 3e-34
Identities = 75/186 (40%), Positives = 95/186 (51%), Gaps = 14/186 (7%)
Frame = +3
Query: 9 VNTIGSFRC-----VCGPGYRPAGRGVRGRD--ECAVRPPPCD--QLCHNTDGSYDCLCR 161
+NT+GS+ C +C GY + G + D EC C Q+CHN GSY C C+
Sbjct: 828 INTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCK 887
Query: 162 TGYELDEDGANCRDVDEC-ERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINEC 332
G++ D G C DV+EC CQ C NT GSY CSC G+ G C D+NEC
Sbjct: 888 AGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNEC 947
Query: 333 HEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG--RCQAPCRNYAGG 506
E C C N+ GS++C C +GY+L +G C D DECAQ C C N G
Sbjct: 948 -EAQRCSQ--ECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGS 1004
Query: 507 YRCDCP 524
Y+C CP
Sbjct: 1005 YQCACP 1010
Score = 134 bits (323), Expect = 3e-31
Identities = 84/204 (41%), Positives = 101/204 (49%), Gaps = 23/204 (11%)
Frame = +3
Query: 9 VNTIGSFRC----VCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCL----C 158
VNT+GSF C C PGY DECA+ C LC NT GS+ C C
Sbjct: 737 VNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRC 796
Query: 159 RTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECS-----CEDGYEKRGDA-- 311
G+ D +G NC D++EC + C+ C NT GSY C C GY D
Sbjct: 797 MDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGAK 855
Query: 312 CVDINECHEEGV--CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGR-CQ 479
CVD+NEC E GV C C NL GS+RC C G++ DA G C+D +EC A GR CQ
Sbjct: 856 CVDVNEC-ETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQ 914
Query: 480 APCRNYAGGYRCDCPVGTVRSPSG 551
C N G YRC C G + + G
Sbjct: 915 HTCENTLGSYRCSCASGFLLAADG 938
Score = 119 bits (287), Expect = 6e-27
Identities = 67/169 (39%), Positives = 84/169 (49%), Gaps = 9/169 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
NT+GS+RC C G+ A G R D C Q C N GSY C CR GY+L EDG
Sbjct: 919 NTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQCYCRQGYQLAEDGH 978
Query: 192 NCRDVDECERDTH-TCQQICSNTEGSYECSC-EDGY--EKRGDACVDINECH-EEGVCPS 356
C D+DEC + C C N GSY+C+C E GY G +C D++EC C
Sbjct: 979 TCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSE 1038
Query: 357 PGRCVNLLGSFRCV---CPRGYRLDAEGARCVDRDECAQTGRCQ-APCR 491
C N+ GSFRC+ CP Y + +C +R C CQ +P R
Sbjct: 1039 AETCHNIQGSFRCLRLECPPNY-VQVSKTKC-ERTTCHDFLECQNSPAR 1085
Score = 102 bits (245), Expect = 7e-22
Identities = 58/150 (38%), Positives = 71/150 (47%), Gaps = 14/150 (9%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-- 275
PC Q+C GS C C GY + DG +C D++EC D HTC + C NT GS+ C
Sbjct: 688 PCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYK 747
Query: 276 --SCEDGYEKRGDACVDINECHEEGVCPSPG-RCVNLLGSFRCV----CPRGYRLDAEGA 434
+CE GY + C D++EC PG C N GSF C C G+ D EG
Sbjct: 748 ALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG- 806
Query: 435 RCVDRDECAQTGRCQAP---CRNYAGGYRC 515
CVD +EC P C N G Y C
Sbjct: 807 NCVDINECTSLSEPCRPGFSCINTVGSYTC 836
Score = 83.8 bits (198), Expect = 4e-16
Identities = 65/195 (33%), Positives = 81/195 (41%), Gaps = 14/195 (7%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+NT+GS+ C C PG+ G R E P Q + + L
Sbjct: 621 INTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQE-PALKSEFSQVASNTIPLPLPQ 679
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEE-GVCPSP 359
N C +D C+Q+CS GS CSC GY D +C DINEC + C
Sbjct: 680 PN-----TC-KDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRG 733
Query: 360 GRCVNLLGSFRC----VCPRGYRLDAEGARCVDRDECAQ-TGRCQAP--CRNYAGGYRCD 518
CVN LGSF C C GY L + C D DECA T CQ C+N G + C
Sbjct: 734 EHCVNTLGSFHCYKALTCEPGYAL--KDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQ 791
Query: 519 ----CPVGTVRSPSG 551
C G ++ P G
Sbjct: 792 ARQRCMDGFLQDPEG 806
Score = 62.5 bits (145), Expect = 1e-09
Identities = 46/154 (29%), Positives = 63/154 (40%), Gaps = 9/154 (5%)
Frame = +3
Query: 81 RDECAVRPPP-CDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNT 257
+DEC + P C LC NT GSY C C G+ L +DG CR + H Q
Sbjct: 605 QDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRP------EGHPPQ-----P 653
Query: 258 EGSYECSCEDGYEKRGDACVDI-----NECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLD 422
E E + + + + + + N C + G C C + GS C C GY +
Sbjct: 654 EAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQV--CSTVGGSAICSCFPGYAIM 711
Query: 423 AEGARCVDRDECA---QTGRCQAPCRNYAGGYRC 515
A+G C D +EC T C N G + C
Sbjct: 712 ADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHC 745
>AY130459-1|AAN05436.1| 1231|Homo sapiens fibulin 2 protein.
Length = 1231
Score = 144 bits (349), Expect = 2e-34
Identities = 79/188 (42%), Positives = 100/188 (53%), Gaps = 12/188 (6%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY-RPA-GRGVRGRDECAVRPPP-CDQLCHNTDGSYDCLCRTGYELDE 182
N GS+RC C G+ R A GRG +EC P C C NT GSY C C +G+ L
Sbjct: 924 NLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAA 983
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPS 356
DG C DV+ECE C Q C+N GSY+C C GY+ + G C DI+EC +
Sbjct: 984 DGKRCEDVNECE--AQRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILC 1041
Query: 357 PGRCVNLLGSFRCVCP-RGYRLDAEGARCVDRDECA-QTGRCQ--APCRNYAGGYRC--- 515
RC+N+ GS++C CP +GY + A G C D DECA T C C N G +RC
Sbjct: 1042 TFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRF 1101
Query: 516 DCPVGTVR 539
+CP V+
Sbjct: 1102 ECPPNYVQ 1109
Score = 143 bits (347), Expect = 3e-34
Identities = 75/186 (40%), Positives = 95/186 (51%), Gaps = 14/186 (7%)
Frame = +3
Query: 9 VNTIGSFRC-----VCGPGYRPAGRGVRGRD--ECAVRPPPCD--QLCHNTDGSYDCLCR 161
+NT+GS+ C +C GY + G + D EC C Q+CHN GSY C C+
Sbjct: 875 INTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCK 934
Query: 162 TGYELDEDGANCRDVDEC-ERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINEC 332
G++ D G C DV+EC CQ C NT GSY CSC G+ G C D+NEC
Sbjct: 935 AGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNEC 994
Query: 333 HEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG--RCQAPCRNYAGG 506
E C C N+ GS++C C +GY+L +G C D DECAQ C C N G
Sbjct: 995 -EAQRCSQ--ECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGS 1051
Query: 507 YRCDCP 524
Y+C CP
Sbjct: 1052 YQCACP 1057
Score = 134 bits (323), Expect = 3e-31
Identities = 84/204 (41%), Positives = 101/204 (49%), Gaps = 23/204 (11%)
Frame = +3
Query: 9 VNTIGSFRC----VCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCL----C 158
VNT+GSF C C PGY DECA+ C LC NT GS+ C C
Sbjct: 784 VNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRC 843
Query: 159 RTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECS-----CEDGYEKRGDA-- 311
G+ D +G NC D++EC + C+ C NT GSY C C GY D
Sbjct: 844 MDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGAK 902
Query: 312 CVDINECHEEGV--CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGR-CQ 479
CVD+NEC E GV C C NL GS+RC C G++ DA G C+D +EC A GR CQ
Sbjct: 903 CVDVNEC-ETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQ 961
Query: 480 APCRNYAGGYRCDCPVGTVRSPSG 551
C N G YRC C G + + G
Sbjct: 962 HTCENTLGSYRCSCASGFLLAADG 985
Score = 119 bits (287), Expect = 6e-27
Identities = 67/169 (39%), Positives = 84/169 (49%), Gaps = 9/169 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
NT+GS+RC C G+ A G R D C Q C N GSY C CR GY+L EDG
Sbjct: 966 NTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQCYCRQGYQLAEDGH 1025
Query: 192 NCRDVDECERDTH-TCQQICSNTEGSYECSC-EDGY--EKRGDACVDINECH-EEGVCPS 356
C D+DEC + C C N GSY+C+C E GY G +C D++EC C
Sbjct: 1026 TCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSE 1085
Query: 357 PGRCVNLLGSFRCV---CPRGYRLDAEGARCVDRDECAQTGRCQ-APCR 491
C N+ GSFRC+ CP Y + +C +R C CQ +P R
Sbjct: 1086 AETCHNIQGSFRCLRFECPPNY-VQVSKTKC-ERTTCHDFLECQNSPAR 1132
Score = 101 bits (242), Expect = 2e-21
Identities = 65/168 (38%), Positives = 76/168 (45%), Gaps = 20/168 (11%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYEC-- 275
PC Q+C GS C C GY + DG +C D DEC H C +Q C NT GS+ C
Sbjct: 688 PCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVN 747
Query: 276 ---SCEDGYEKRGD-ACVDINECHEE-GVCPSPGRCVNLLGSFRC----VCPRGYRLDAE 428
C DGY CV NEC + C CVN LGSF C C GY L +
Sbjct: 748 HTVLCADGYILNAHRKCVGKNECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYAL--K 805
Query: 429 GARCVDRDECAQ-TGRCQAP--CRNYAGGYRCD----CPVGTVRSPSG 551
C D DECA T CQ C+N G + C C G ++ P G
Sbjct: 806 DGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG 853
Score = 68.1 bits (159), Expect = 2e-11
Identities = 57/180 (31%), Positives = 73/180 (40%), Gaps = 11/180 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+NT+GS+ C C PG+ G R E P Q + + L
Sbjct: 621 INTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQE-PALKSEFSQVASNTIPLPLPQ 679
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINEC-HEEGVCPSP 359
N C +D C+Q+CS GS CSC GY D +C D +EC C
Sbjct: 680 PN-----TC-KDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRR 733
Query: 360 GRCVNLLGSFRCV-----CPRGYRLDAEGARCVDRDECA---QTGRCQAPCRNYAGGYRC 515
CVN LGSF CV C GY L+A +CV ++EC T C N G + C
Sbjct: 734 QFCVNTLGSFYCVNHTVLCADGYILNAH-RKCVGKNECVTDLHTCSRGEHCVNTLGSFHC 792
Score = 65.7 bits (153), Expect = 1e-10
Identities = 47/154 (30%), Positives = 64/154 (41%), Gaps = 9/154 (5%)
Frame = +3
Query: 81 RDECAVRPPP-CDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNT 257
+DEC + P C LC NT GSY C C G+ L +DG CR + H Q
Sbjct: 605 QDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRP------EGHPPQ-----P 653
Query: 258 EGSYECSCEDGYEKRGDACVDI-----NECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLD 422
E E + + + + + + N C + G C C + GS C C GY +
Sbjct: 654 EAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQV--CSTVGGSAICSCFPGYAIM 711
Query: 423 AEGARCVDRDECAQTGR-CQAP--CRNYAGGYRC 515
A+G C D+DEC C C N G + C
Sbjct: 712 ADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYC 745
>AY130458-1|AAN05435.1| 1231|Homo sapiens fibulin 2 protein.
Length = 1231
Score = 144 bits (349), Expect = 2e-34
Identities = 79/188 (42%), Positives = 100/188 (53%), Gaps = 12/188 (6%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY-RPA-GRGVRGRDECAVRPPP-CDQLCHNTDGSYDCLCRTGYELDE 182
N GS+RC C G+ R A GRG +EC P C C NT GSY C C +G+ L
Sbjct: 924 NLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAA 983
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPS 356
DG C DV+ECE C Q C+N GSY+C C GY+ + G C DI+EC +
Sbjct: 984 DGKRCEDVNECE--AQRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILC 1041
Query: 357 PGRCVNLLGSFRCVCP-RGYRLDAEGARCVDRDECA-QTGRCQ--APCRNYAGGYRC--- 515
RC+N+ GS++C CP +GY + A G C D DECA T C C N G +RC
Sbjct: 1042 TFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRF 1101
Query: 516 DCPVGTVR 539
+CP V+
Sbjct: 1102 ECPPNYVQ 1109
Score = 143 bits (346), Expect = 4e-34
Identities = 75/186 (40%), Positives = 95/186 (51%), Gaps = 14/186 (7%)
Frame = +3
Query: 9 VNTIGSFRC-----VCGPGYRPAGRGVRGRD--ECAVRPPPCD--QLCHNTDGSYDCLCR 161
+NT+GS+ C +C GY + G + D EC C Q+CHN GSY C C+
Sbjct: 875 INTVGSYTCQRNPLICARGYHASDDGXKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCK 934
Query: 162 TGYELDEDGANCRDVDEC-ERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINEC 332
G++ D G C DV+EC CQ C NT GSY CSC G+ G C D+NEC
Sbjct: 935 AGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNEC 994
Query: 333 HEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG--RCQAPCRNYAGG 506
E C C N+ GS++C C +GY+L +G C D DECAQ C C N G
Sbjct: 995 -EAQRCSQ--ECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGS 1051
Query: 507 YRCDCP 524
Y+C CP
Sbjct: 1052 YQCACP 1057
Score = 134 bits (323), Expect = 3e-31
Identities = 84/204 (41%), Positives = 101/204 (49%), Gaps = 23/204 (11%)
Frame = +3
Query: 9 VNTIGSFRC----VCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCL----C 158
VNT+GSF C C PGY DECA+ C LC NT GS+ C C
Sbjct: 784 VNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRC 843
Query: 159 RTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECS-----CEDGYEKRGDA-- 311
G+ D +G NC D++EC + C+ C NT GSY C C GY D
Sbjct: 844 MDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGXK 902
Query: 312 CVDINECHEEGV--CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGR-CQ 479
CVD+NEC E GV C C NL GS+RC C G++ DA G C+D +EC A GR CQ
Sbjct: 903 CVDVNEC-ETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQ 961
Query: 480 APCRNYAGGYRCDCPVGTVRSPSG 551
C N G YRC C G + + G
Sbjct: 962 HTCENTLGSYRCSCASGFLLAADG 985
Score = 119 bits (287), Expect = 6e-27
Identities = 67/169 (39%), Positives = 84/169 (49%), Gaps = 9/169 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
NT+GS+RC C G+ A G R D C Q C N GSY C CR GY+L EDG
Sbjct: 966 NTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQCYCRQGYQLAEDGH 1025
Query: 192 NCRDVDECERDTH-TCQQICSNTEGSYECSC-EDGY--EKRGDACVDINECH-EEGVCPS 356
C D+DEC + C C N GSY+C+C E GY G +C D++EC C
Sbjct: 1026 TCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSE 1085
Query: 357 PGRCVNLLGSFRCV---CPRGYRLDAEGARCVDRDECAQTGRCQ-APCR 491
C N+ GSFRC+ CP Y + +C +R C CQ +P R
Sbjct: 1086 AETCHNIQGSFRCLRFECPPNY-VQVSKTKC-ERTTCHDFLECQNSPAR 1132
Score = 107 bits (256), Expect = 3e-23
Identities = 67/168 (39%), Positives = 78/168 (46%), Gaps = 20/168 (11%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYEC-- 275
PC Q+C GS C C GY + DG +C D DEC H C +Q C NT GS+ C
Sbjct: 688 PCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVN 747
Query: 276 ---SCEDGYEKRGD-ACVDINECHEE-GVCPSPGRCVNLLGSFRC----VCPRGYRLDAE 428
C DGY CVDINEC + C CVN LGSF C C GY L +
Sbjct: 748 HTVLCADGYILNAHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYAL--K 805
Query: 429 GARCVDRDECAQ-TGRCQAP--CRNYAGGYRCD----CPVGTVRSPSG 551
C D DECA T CQ C+N G + C C G ++ P G
Sbjct: 806 DGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG 853
Score = 68.9 bits (161), Expect = 1e-11
Identities = 58/180 (32%), Positives = 73/180 (40%), Gaps = 11/180 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+NT+GS+ C C PG+ G R E P Q + + L
Sbjct: 621 INTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQE-PALKSEFSQVASNTIPLPLPQ 679
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINEC-HEEGVCPSP 359
N C +D C+Q+CS GS CSC GY D +C D +EC C
Sbjct: 680 PN-----TC-KDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRR 733
Query: 360 GRCVNLLGSFRCV-----CPRGYRLDAEGARCVDRDECA---QTGRCQAPCRNYAGGYRC 515
CVN LGSF CV C GY L+A +CVD +EC T C N G + C
Sbjct: 734 QFCVNTLGSFYCVNHTVLCADGYILNAH-RKCVDINECVTDLHTCSRGEHCVNTLGSFHC 792
Score = 65.7 bits (153), Expect = 1e-10
Identities = 47/154 (30%), Positives = 64/154 (41%), Gaps = 9/154 (5%)
Frame = +3
Query: 81 RDECAVRPPP-CDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNT 257
+DEC + P C LC NT GSY C C G+ L +DG CR + H Q
Sbjct: 605 QDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRP------EGHPPQ-----P 653
Query: 258 EGSYECSCEDGYEKRGDACVDI-----NECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLD 422
E E + + + + + + N C + G C C + GS C C GY +
Sbjct: 654 EAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQV--CSTVGGSAICSCFPGYAIM 711
Query: 423 AEGARCVDRDECAQTGR-CQAP--CRNYAGGYRC 515
A+G C D+DEC C C N G + C
Sbjct: 712 ADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYC 745
>AB209212-1|BAD92449.1| 418|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 1 isoform b
variant protein.
Length = 418
Score = 143 bits (347), Expect = 3e-34
Identities = 71/174 (40%), Positives = 94/174 (54%), Gaps = 5/174 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+N GSF C C PGY+ G DEC + PP C Q C NT GS+ C C G++L +
Sbjct: 116 INLRGSFACQCPPGYQKRGEQCVDIDECTI-PPYCHQRCVNTPGSFYCQCSPGFQLAANN 174
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEG-VCPSP 359
C D++EC+ ++ C Q C N GS+ C C GYE D C DI+EC +C
Sbjct: 175 YTCVDINECDA-SNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQY- 232
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRC 515
+CVN G F C+CP+GY++ C D +EC T C+ C NY GG+RC
Sbjct: 233 -QCVNQPGKFSCMCPQGYQV-VRSRTCQDINECETTNECREDEMCWNYHGGFRC 284
Score = 131 bits (316), Expect = 2e-30
Identities = 62/153 (40%), Positives = 81/153 (52%), Gaps = 2/153 (1%)
Frame = +3
Query: 78 GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICS 251
GR+ +R P D ++ S+ C GYE E C+D+DEC TH C+ Q+C
Sbjct: 58 GRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNV-CQDIDECTAGTHNCRADQVCI 116
Query: 252 NTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEG 431
N GS+ C C GY+KRG+ CVDI+EC C RCVN GSF C C G++L A
Sbjct: 117 NLRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQ--RCVNTPGSFYCQCSPGFQLAANN 174
Query: 432 ARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
CVD +EC + +C C N G + C C G
Sbjct: 175 YTCVDINECDASNQCAQQCYNILGSFICQCNQG 207
Score = 130 bits (315), Expect = 2e-30
Identities = 69/175 (39%), Positives = 88/175 (50%), Gaps = 6/175 (3%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGV-RGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGAN 194
S R C GY + V + DEC C DQ+C N GS+ C C GY+ + G
Sbjct: 79 SHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQ--KRGEQ 136
Query: 195 CRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRC 368
C D+DEC + C Q C NT GS+ C C G++ + CVDINEC C +C
Sbjct: 137 CVDIDECTIPPY-CHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQ--QC 193
Query: 369 VNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG-RCQAPCRNYAGGYRCDCPVG 530
N+LGSF C C +GY L ++ C D DEC + CQ C N G + C CP G
Sbjct: 194 YNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNQPGKFSCMCPQG 248
Score = 119 bits (286), Expect = 8e-27
Identities = 64/154 (41%), Positives = 73/154 (47%), Gaps = 7/154 (4%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
R VNT GSF C C PG++ A D EC C Q C+N GS+ C C GYEL
Sbjct: 152 RCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQ-CAQQCYNILGSFICQCNQGYEL 210
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE-KRGDACVDINECHEEGVCP 353
D NC D+DEC ++ CQ C N G + C C GY+ R C DINEC C
Sbjct: 211 SSDRLNCEDIDECRTSSYLCQYQCVNQPGKFSCMCPQGYQVVRSRTCQDINECETTNECR 270
Query: 354 SPGRCVNLLGSFRCV----CPRGYRLDAEGARCV 443
C N G FRC C Y L E RCV
Sbjct: 271 EDEMCWNYHGGFRCYPRNPCQDPYILTPEN-RCV 303
>U03877-1|AAA65590.1| 387|Homo sapiens extracellular protein
protein.
Length = 387
Score = 143 bits (346), Expect = 4e-34
Identities = 71/174 (40%), Positives = 94/174 (54%), Gaps = 5/174 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+N GSF C C PGY+ G DEC + PP C Q C NT GS+ C C G++L +
Sbjct: 85 INLRGSFACQCPPGYQKRGEQCVDIDECTI-PPYCHQRCVNTPGSFYCQCSPGFQLAANN 143
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEG-VCPSP 359
C D++EC+ ++ C Q C N GS+ C C GYE D C DI+EC +C
Sbjct: 144 YTCVDINECDA-SNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQY- 201
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRC 515
+CVN G F C+CP+GY++ C D +EC T C+ C NY GG+RC
Sbjct: 202 -QCVNEPGKFSCMCPQGYQV-VRSRTCQDINECETTNECREDEMCWNYHGGFRC 253
Score = 131 bits (316), Expect = 2e-30
Identities = 62/153 (40%), Positives = 81/153 (52%), Gaps = 2/153 (1%)
Frame = +3
Query: 78 GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICS 251
GR+ +R P D ++ S+ C GYE E C+D+DEC TH C+ Q+C
Sbjct: 27 GRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNV-CQDIDECTAGTHNCRADQVCI 85
Query: 252 NTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEG 431
N GS+ C C GY+KRG+ CVDI+EC C RCVN GSF C C G++L A
Sbjct: 86 NLRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQ--RCVNTPGSFYCQCSPGFQLAANN 143
Query: 432 ARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
CVD +EC + +C C N G + C C G
Sbjct: 144 YTCVDINECDASNQCAQQCYNILGSFICQCNQG 176
Score = 130 bits (314), Expect = 3e-30
Identities = 69/175 (39%), Positives = 88/175 (50%), Gaps = 6/175 (3%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGV-RGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGAN 194
S R C GY + V + DEC C DQ+C N GS+ C C GY+ + G
Sbjct: 48 SHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQ--KRGEQ 105
Query: 195 CRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRC 368
C D+DEC + C Q C NT GS+ C C G++ + CVDINEC C +C
Sbjct: 106 CVDIDECTIPPY-CHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQ--QC 162
Query: 369 VNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG-RCQAPCRNYAGGYRCDCPVG 530
N+LGSF C C +GY L ++ C D DEC + CQ C N G + C CP G
Sbjct: 163 YNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQG 217
Score = 119 bits (286), Expect = 8e-27
Identities = 64/154 (41%), Positives = 73/154 (47%), Gaps = 7/154 (4%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
R VNT GSF C C PG++ A D EC C Q C+N GS+ C C GYEL
Sbjct: 121 RCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQ-CAQQCYNILGSFICQCNQGYEL 179
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE-KRGDACVDINECHEEGVCP 353
D NC D+DEC ++ CQ C N G + C C GY+ R C DINEC C
Sbjct: 180 SSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTNECR 239
Query: 354 SPGRCVNLLGSFRCV----CPRGYRLDAEGARCV 443
C N G FRC C Y L E RCV
Sbjct: 240 EDEMCWNYHGGFRCYPRNPCQDPYILTPEN-RCV 272
>BC098561-1|AAH98561.1| 493|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 1 protein.
Length = 493
Score = 143 bits (346), Expect = 4e-34
Identities = 71/174 (40%), Positives = 94/174 (54%), Gaps = 5/174 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+N GSF C C PGY+ G DEC + PP C Q C NT GS+ C C G++L +
Sbjct: 191 INLRGSFACQCPPGYQKRGEQCVDIDECTI-PPYCHQRCVNTPGSFYCQCSPGFQLAANN 249
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEG-VCPSP 359
C D++EC+ ++ C Q C N GS+ C C GYE D C DI+EC +C
Sbjct: 250 YTCVDINECDA-SNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQY- 307
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRC 515
+CVN G F C+CP+GY++ C D +EC T C+ C NY GG+RC
Sbjct: 308 -QCVNEPGKFSCMCPQGYQV-VRSRTCQDINECETTNECREDEMCWNYHGGFRC 359
Score = 131 bits (316), Expect = 2e-30
Identities = 62/153 (40%), Positives = 81/153 (52%), Gaps = 2/153 (1%)
Frame = +3
Query: 78 GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICS 251
GR+ +R P D ++ S+ C GYE E C+D+DEC TH C+ Q+C
Sbjct: 133 GRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNV-CQDIDECTAGTHNCRADQVCI 191
Query: 252 NTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEG 431
N GS+ C C GY+KRG+ CVDI+EC C RCVN GSF C C G++L A
Sbjct: 192 NLRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQ--RCVNTPGSFYCQCSPGFQLAANN 249
Query: 432 ARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
CVD +EC + +C C N G + C C G
Sbjct: 250 YTCVDINECDASNQCAQQCYNILGSFICQCNQG 282
Score = 130 bits (314), Expect = 3e-30
Identities = 69/175 (39%), Positives = 88/175 (50%), Gaps = 6/175 (3%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGV-RGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGAN 194
S R C GY + V + DEC C DQ+C N GS+ C C GY+ + G
Sbjct: 154 SHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQ--KRGEQ 211
Query: 195 CRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRC 368
C D+DEC + C Q C NT GS+ C C G++ + CVDINEC C +C
Sbjct: 212 CVDIDECTIPPY-CHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQ--QC 268
Query: 369 VNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG-RCQAPCRNYAGGYRCDCPVG 530
N+LGSF C C +GY L ++ C D DEC + CQ C N G + C CP G
Sbjct: 269 YNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQG 323
Score = 119 bits (286), Expect = 8e-27
Identities = 64/154 (41%), Positives = 73/154 (47%), Gaps = 7/154 (4%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
R VNT GSF C C PG++ A D EC C Q C+N GS+ C C GYEL
Sbjct: 227 RCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQ-CAQQCYNILGSFICQCNQGYEL 285
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE-KRGDACVDINECHEEGVCP 353
D NC D+DEC ++ CQ C N G + C C GY+ R C DINEC C
Sbjct: 286 SSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTNECR 345
Query: 354 SPGRCVNLLGSFRCV----CPRGYRLDAEGARCV 443
C N G FRC C Y L E RCV
Sbjct: 346 EDEMCWNYHGGFRCYPRNPCQDPYILTPEN-RCV 378
Score = 35.5 bits (78), Expect = 0.12
Identities = 16/42 (38%), Positives = 20/42 (47%), Gaps = 2/42 (4%)
Frame = +3
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC 275
C GYE D C+D+DEC+ C+ C N G Y C
Sbjct: 29 CTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLC 70
Score = 30.3 bits (65), Expect = 4.7
Identities = 16/42 (38%), Positives = 19/42 (45%), Gaps = 3/42 (7%)
Frame = +3
Query: 399 CPRGYRLDAEGARCVDRDEC-AQTGRCQA--PCRNYAGGYRC 515
C GY D +C D DEC C+ C N+ GGY C
Sbjct: 29 CTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLC 70
>BC014410-1|AAH14410.1| 493|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 1 protein.
Length = 493
Score = 143 bits (346), Expect = 4e-34
Identities = 71/174 (40%), Positives = 94/174 (54%), Gaps = 5/174 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+N GSF C C PGY+ G DEC + PP C Q C NT GS+ C C G++L +
Sbjct: 191 INLRGSFACQCPPGYQKRGEQCVDIDECTI-PPYCHQRCVNTPGSFYCQCSPGFQLAANN 249
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEG-VCPSP 359
C D++EC+ ++ C Q C N GS+ C C GYE D C DI+EC +C
Sbjct: 250 YTCVDINECDA-SNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQY- 307
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRC 515
+CVN G F C+CP+GY++ C D +EC T C+ C NY GG+RC
Sbjct: 308 -QCVNEPGKFSCMCPQGYQV-VRSRTCQDINECETTNECREDEMCWNYHGGFRC 359
Score = 131 bits (316), Expect = 2e-30
Identities = 62/153 (40%), Positives = 81/153 (52%), Gaps = 2/153 (1%)
Frame = +3
Query: 78 GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICS 251
GR+ +R P D ++ S+ C GYE E C+D+DEC TH C+ Q+C
Sbjct: 133 GRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNV-CQDIDECTAGTHNCRADQVCI 191
Query: 252 NTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEG 431
N GS+ C C GY+KRG+ CVDI+EC C RCVN GSF C C G++L A
Sbjct: 192 NLRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQ--RCVNTPGSFYCQCSPGFQLAANN 249
Query: 432 ARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
CVD +EC + +C C N G + C C G
Sbjct: 250 YTCVDINECDASNQCAQQCYNILGSFICQCNQG 282
Score = 130 bits (314), Expect = 3e-30
Identities = 69/175 (39%), Positives = 88/175 (50%), Gaps = 6/175 (3%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGV-RGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGAN 194
S R C GY + V + DEC C DQ+C N GS+ C C GY+ + G
Sbjct: 154 SHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQ--KRGEQ 211
Query: 195 CRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRC 368
C D+DEC + C Q C NT GS+ C C G++ + CVDINEC C +C
Sbjct: 212 CVDIDECTIPPY-CHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQ--QC 268
Query: 369 VNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG-RCQAPCRNYAGGYRCDCPVG 530
N+LGSF C C +GY L ++ C D DEC + CQ C N G + C CP G
Sbjct: 269 YNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQG 323
Score = 119 bits (286), Expect = 8e-27
Identities = 64/154 (41%), Positives = 73/154 (47%), Gaps = 7/154 (4%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
R VNT GSF C C PG++ A D EC C Q C+N GS+ C C GYEL
Sbjct: 227 RCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQ-CAQQCYNILGSFICQCNQGYEL 285
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE-KRGDACVDINECHEEGVCP 353
D NC D+DEC ++ CQ C N G + C C GY+ R C DINEC C
Sbjct: 286 SSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTNECR 345
Query: 354 SPGRCVNLLGSFRCV----CPRGYRLDAEGARCV 443
C N G FRC C Y L E RCV
Sbjct: 346 EDEMCWNYHGGFRCYPRNPCQDPYILTPEN-RCV 378
Score = 35.5 bits (78), Expect = 0.12
Identities = 16/42 (38%), Positives = 20/42 (47%), Gaps = 2/42 (4%)
Frame = +3
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC 275
C GYE D C+D+DEC+ C+ C N G Y C
Sbjct: 29 CTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLC 70
Score = 30.3 bits (65), Expect = 4.7
Identities = 16/42 (38%), Positives = 19/42 (45%), Gaps = 3/42 (7%)
Frame = +3
Query: 399 CPRGYRLDAEGARCVDRDEC-AQTGRCQA--PCRNYAGGYRC 515
C GY D +C D DEC C+ C N+ GGY C
Sbjct: 29 CTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLC 70
>AY004330-1|AAK11491.1| 493|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 1 protein.
Length = 493
Score = 143 bits (346), Expect = 4e-34
Identities = 71/174 (40%), Positives = 94/174 (54%), Gaps = 5/174 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+N GSF C C PGY+ G DEC + PP C Q C NT GS+ C C G++L +
Sbjct: 191 INLRGSFACQCPPGYQKRGEQCVDIDECTI-PPYCHQRCVNTPGSFYCQCSPGFQLAANN 249
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEG-VCPSP 359
C D++EC+ ++ C Q C N GS+ C C GYE D C DI+EC +C
Sbjct: 250 YTCVDINECDA-SNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQY- 307
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRC 515
+CVN G F C+CP+GY++ C D +EC T C+ C NY GG+RC
Sbjct: 308 -QCVNEPGKFSCMCPQGYQV-VRSRTCQDINECETTNECREDEMCWNYHGGFRC 359
Score = 131 bits (316), Expect = 2e-30
Identities = 62/153 (40%), Positives = 81/153 (52%), Gaps = 2/153 (1%)
Frame = +3
Query: 78 GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICS 251
GR+ +R P D ++ S+ C GYE E C+D+DEC TH C+ Q+C
Sbjct: 133 GRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNV-CQDIDECTAGTHNCRADQVCI 191
Query: 252 NTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEG 431
N GS+ C C GY+KRG+ CVDI+EC C RCVN GSF C C G++L A
Sbjct: 192 NLRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQ--RCVNTPGSFYCQCSPGFQLAANN 249
Query: 432 ARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
CVD +EC + +C C N G + C C G
Sbjct: 250 YTCVDINECDASNQCAQQCYNILGSFICQCNQG 282
Score = 130 bits (314), Expect = 3e-30
Identities = 69/175 (39%), Positives = 88/175 (50%), Gaps = 6/175 (3%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGV-RGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGAN 194
S R C GY + V + DEC C DQ+C N GS+ C C GY+ + G
Sbjct: 154 SHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQ--KRGEQ 211
Query: 195 CRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRC 368
C D+DEC + C Q C NT GS+ C C G++ + CVDINEC C +C
Sbjct: 212 CVDIDECTIPPY-CHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQ--QC 268
Query: 369 VNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG-RCQAPCRNYAGGYRCDCPVG 530
N+LGSF C C +GY L ++ C D DEC + CQ C N G + C CP G
Sbjct: 269 YNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQG 323
Score = 119 bits (286), Expect = 8e-27
Identities = 64/154 (41%), Positives = 73/154 (47%), Gaps = 7/154 (4%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
R VNT GSF C C PG++ A D EC C Q C+N GS+ C C GYEL
Sbjct: 227 RCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQ-CAQQCYNILGSFICQCNQGYEL 285
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE-KRGDACVDINECHEEGVCP 353
D NC D+DEC ++ CQ C N G + C C GY+ R C DINEC C
Sbjct: 286 SSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTNECR 345
Query: 354 SPGRCVNLLGSFRCV----CPRGYRLDAEGARCV 443
C N G FRC C Y L E RCV
Sbjct: 346 EDEMCWNYHGGFRCYPRNPCQDPYILTPEN-RCV 378
Score = 35.5 bits (78), Expect = 0.12
Identities = 16/42 (38%), Positives = 20/42 (47%), Gaps = 2/42 (4%)
Frame = +3
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC 275
C GYE D C+D+DEC+ C+ C N G Y C
Sbjct: 29 CTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLC 70
Score = 30.3 bits (65), Expect = 4.7
Identities = 16/42 (38%), Positives = 19/42 (45%), Gaps = 3/42 (7%)
Frame = +3
Query: 399 CPRGYRLDAEGARCVDRDEC-AQTGRCQA--PCRNYAGGYRC 515
C GY D +C D DEC C+ C N+ GGY C
Sbjct: 29 CTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLC 70
>AC010895-1|AAY14669.1| 320|Homo sapiens unknown protein.
Length = 320
Score = 143 bits (346), Expect = 4e-34
Identities = 71/174 (40%), Positives = 94/174 (54%), Gaps = 5/174 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+N GSF C C PGY+ G DEC + PP C Q C NT GS+ C C G++L +
Sbjct: 18 INLRGSFACQCPPGYQKRGEQCVDIDECTI-PPYCHQRCVNTPGSFYCQCSPGFQLAANN 76
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEG-VCPSP 359
C D++EC+ ++ C Q C N GS+ C C GYE D C DI+EC +C
Sbjct: 77 YTCVDINECDA-SNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQY- 134
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRC 515
+CVN G F C+CP+GY++ C D +EC T C+ C NY GG+RC
Sbjct: 135 -QCVNEPGKFSCMCPQGYQV-VRSRTCQDINECETTNECREDEMCWNYHGGFRC 186
Score = 124 bits (300), Expect = 2e-28
Identities = 63/154 (40%), Positives = 80/154 (51%), Gaps = 5/154 (3%)
Frame = +3
Query: 84 DECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNT 257
DEC C DQ+C N GS+ C C GY+ + G C D+DEC + C Q C NT
Sbjct: 2 DECTAGTHNCRADQVCINLRGSFACQCPPGYQ--KRGEQCVDIDECTIPPY-CHQRCVNT 58
Query: 258 EGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEG 431
GS+ C C G++ + CVDINEC C +C N+LGSF C C +GY L ++
Sbjct: 59 PGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQ--QCYNILGSFICQCNQGYELSSDR 116
Query: 432 ARCVDRDECAQTG-RCQAPCRNYAGGYRCDCPVG 530
C D DEC + CQ C N G + C CP G
Sbjct: 117 LNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQG 150
Score = 119 bits (286), Expect = 8e-27
Identities = 64/154 (41%), Positives = 73/154 (47%), Gaps = 7/154 (4%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
R VNT GSF C C PG++ A D EC C Q C+N GS+ C C GYEL
Sbjct: 54 RCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQ-CAQQCYNILGSFICQCNQGYEL 112
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE-KRGDACVDINECHEEGVCP 353
D NC D+DEC ++ CQ C N G + C C GY+ R C DINEC C
Sbjct: 113 SSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTNECR 172
Query: 354 SPGRCVNLLGSFRCV----CPRGYRLDAEGARCV 443
C N G FRC C Y L E RCV
Sbjct: 173 EDEMCWNYHGGFRCYPRNPCQDPYILTPEN-RCV 205
Score = 111 bits (266), Expect = 2e-24
Identities = 49/111 (44%), Positives = 62/111 (55%), Gaps = 2/111 (1%)
Frame = +3
Query: 204 VDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNL 377
+DEC TH C+ Q+C N GS+ C C GY+KRG+ CVDI+EC C RCVN
Sbjct: 1 IDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQ--RCVNT 58
Query: 378 LGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
GSF C C G++L A CVD +EC + +C C N G + C C G
Sbjct: 59 PGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQG 109
>AF054502-1|AAC39882.1| 669|Homo sapiens latent transforming growth
factor-beta binding protein 4 protein.
Length = 669
Score = 140 bits (338), Expect = 4e-33
Identities = 80/193 (41%), Positives = 100/193 (51%), Gaps = 12/193 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRG-VRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELD 179
VN+ GSF+C P RG DEC+ PPC C NT+GS+ C C GY
Sbjct: 33 VNSPGSFQCRACPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAP 92
Query: 180 EDGAN-CRDVDEC-ERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGV 347
C DV+EC E D C NT+GS+ C+C GY RG +C+D++EC EE +
Sbjct: 93 SGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDL 152
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG--RCQAP-CRNYAGGYRC- 515
C S G C N GSF C+CP G+R + A C+D DEC + G C + C N G YRC
Sbjct: 153 CQS-GICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCV 211
Query: 516 -DCPVGTVRSPSG 551
DC G P G
Sbjct: 212 RDCDPGYHAGPEG 224
Score = 137 bits (331), Expect = 3e-32
Identities = 82/184 (44%), Positives = 99/184 (53%), Gaps = 13/184 (7%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR-PAGRGVRGRD--ECAVRPPPC--DQLCHNTDGSYDCLCRTGYEL 176
NT GSFRC C PGYR P+GR D EC + C C NTDGS+ C C GY
Sbjct: 76 NTEGSFRCSCAPGYRAPSGRPGPCADVNEC-LEGDFCFPHGECLNTDGSFACTCAPGYRP 134
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEG-- 344
GA+C DVDEC + IC+NT+GS+EC C G+ D +C+D++EC E G
Sbjct: 135 GPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPA 194
Query: 345 VCPSPGRCVNLLGSFRCV--CPRGYRLDAEGARCVDRDEC-AQTGRCQAP-CRNYAGGYR 512
+C S RC N GS+RCV C GY EG C D +EC G C A C N G +
Sbjct: 195 LCGSQ-RCENSPGSYRCVRDCDPGYHAGPEGT-CDDVNECETLQGVCGAALCENVEGSFL 252
Query: 513 CDCP 524
C CP
Sbjct: 253 CVCP 256
Score = 129 bits (311), Expect = 7e-30
Identities = 72/178 (40%), Positives = 87/178 (48%), Gaps = 10/178 (5%)
Frame = +3
Query: 42 GP-GYRP--AGRGVRGRDECAVRPPPCDQLCHNTDGSYDC-LCRTGYELDEDGANCRDVD 209
GP G++P AG DEC Q C N+ GS+ C C +G+ L C DVD
Sbjct: 2 GPMGFQPNAAGSECEDVDECENHLACPGQECVNSPGSFQCRACPSGHHLHR--GRCTDVD 59
Query: 210 ECERDTHTC--QQICSNTEGSYECSCEDGYEK---RGDACVDINECHEEGVCPSPGRCVN 374
EC C C+NTEGS+ CSC GY R C D+NEC E C G C+N
Sbjct: 60 ECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLN 119
Query: 375 LLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP-CRNYAGGYRCDCPVGTVRSP 545
GSF C C GYR GA C+D DEC++ CQ+ C N G + C CP G P
Sbjct: 120 TDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGP 177
Score = 124 bits (300), Expect = 2e-28
Identities = 68/154 (44%), Positives = 82/154 (53%), Gaps = 9/154 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+NT GSF C C PGYRP RG DEC+ +C NTDGS++C+C G+
Sbjct: 118 LNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGP 177
Query: 183 DGANCRDVDEC-ERDTHTC-QQICSNTEGSYEC--SCEDGYEKRGD-ACVDINECHE-EG 344
D A+C DVDEC ER C Q C N+ GSY C C+ GY + C D+NEC +G
Sbjct: 178 DLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVNECETLQG 237
Query: 345 VCPSPGRCVNLLGSFRCVCPRG-YRLDAEGARCV 443
VC C N+ GSF CVCP D RCV
Sbjct: 238 VC-GAALCENVEGSFLCVCPNSPEEFDPMTGRCV 270
Score = 92.3 bits (219), Expect = 1e-18
Identities = 47/134 (35%), Positives = 61/134 (45%), Gaps = 5/134 (3%)
Frame = +3
Query: 165 GYELDEDGANCRDVDECERDTHTCQQICSNTEGSYEC-SCEDGYEKRGDACVDINECHEE 341
G++ + G+ C DVDECE Q C N+ GS++C +C G+ C D++EC
Sbjct: 5 GFQPNAAGSECEDVDECENHLACPGQECVNSPGSFQCRACPSGHHLHRGRCTDVDECSSG 64
Query: 342 G-VCPSPGRCVNLLGSFRCVCPRGYRL-DAEGARCVDRDECAQTGRC--QAPCRNYAGGY 509
C G C N GSFRC C GYR C D +EC + C C N G +
Sbjct: 65 APPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSF 124
Query: 510 RCDCPVGTVRSPSG 551
C C G P G
Sbjct: 125 ACTCAPGYRPGPRG 138
Score = 71.7 bits (168), Expect = 2e-12
Identities = 43/120 (35%), Positives = 54/120 (45%), Gaps = 8/120 (6%)
Frame = +3
Query: 117 QLCHNTD-GSYDCLCR--TGYELDEDGANCR-DVDECE--RDTHTCQQICSNTEGSYECS 278
Q C T+ Y LC GY + R DVDEC+ RD +C NT Y C
Sbjct: 358 QQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCY 417
Query: 279 CEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRD 452
C +GY C+D +EC +E GRCVN +GS+ C C LD RCV +
Sbjct: 418 CSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNE 477
Score = 66.9 bits (156), Expect = 4e-11
Identities = 45/154 (29%), Positives = 63/154 (40%), Gaps = 6/154 (3%)
Frame = +3
Query: 78 GRDEC---AVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECE-RDTHTCQQI 245
GR EC P CD + +C C G + G+ CR + +C +T Q +
Sbjct: 316 GRRECYFDTAAPDACDNILARNVTWQECCCTVG---EGWGSGCR-IQQCPGTETAEYQSL 371
Query: 246 CSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDA 425
C + G S + + D C + + VC S G CVN + C C GY
Sbjct: 372 CPHGRGYLAPSGDLSLRRDVDEC----QLFRDQVCKS-GVCVNTAPGYSCYCSNGYYYHT 426
Query: 426 EGARCVDRDECA-QTGRCQ-APCRNYAGGYRCDC 521
+ C+D DECA + C+ C N G Y C C
Sbjct: 427 QRLECIDNDECADEEPACEGGRCVNTVGSYHCTC 460
Score = 42.7 bits (96), Expect = 8e-04
Identities = 24/66 (36%), Positives = 28/66 (42%), Gaps = 3/66 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCD-QLCHNTDGSYDCLCRTGYELD 179
VNT + C C GY + + DECA P C+ C NT GSY C C LD
Sbjct: 408 VNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLD 467
Query: 180 EDGANC 197
C
Sbjct: 468 GSQRRC 473
>AL513320-1|CAI14334.1| 1229|Homo sapiens multiple EGF-like-domains
6 protein.
Length = 1229
Score = 138 bits (333), Expect = 2e-32
Identities = 70/180 (38%), Positives = 89/180 (49%), Gaps = 10/180 (5%)
Frame = +3
Query: 21 GSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
G RC C GY+ A G+ DECA C C NT GS+ C+C GYEL DG
Sbjct: 159 GLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQ 218
Query: 195 C-----RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCP 353
C V+ CE + C CS+T C+C GYE D C+D+++C + C
Sbjct: 219 CYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQ 278
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQT-GRCQAPCRNYAGGYRCDCPVG 530
C N G + C C GYRL A+G C D DECA + G C+ C N AG ++C C G
Sbjct: 279 QV--CTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAG 336
Score = 132 bits (319), Expect = 8e-31
Identities = 73/188 (38%), Positives = 84/188 (44%), Gaps = 9/188 (4%)
Frame = +3
Query: 15 TIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
TI RC C PG++ GR R CA R C C G C C GY+L DG
Sbjct: 116 TITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADG 175
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDI-----NECHEEGV 347
C DVDEC C C NT+GS++C C GYE D C I N C
Sbjct: 176 KACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNG 235
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPV 527
S G C + C CPRGY LD + C+D D+CA + CQ C N GGY C C
Sbjct: 236 GCSHG-CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYA 294
Query: 528 GTVRSPSG 551
G S G
Sbjct: 295 GYRLSADG 302
Score = 116 bits (280), Expect = 4e-26
Identities = 62/159 (38%), Positives = 76/159 (47%), Gaps = 10/159 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRG-------VRGRDECAVRPPPCDQLCHNTDGSYDCLCRTG 167
+NT GSF+CVC GY G + + C C C +T C C G
Sbjct: 196 LNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRG 255
Query: 168 YELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC--VDINEC-HE 338
YELD D C DVD+C D+ CQQ+C+N G YEC C GY D C D++EC
Sbjct: 256 YELDTDQRTCIDVDDCA-DSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASS 314
Query: 339 EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE 455
G C C NL GSF+C C GYRL + C +E
Sbjct: 315 RGGCEH--HCTNLAGSFQCSCEAGYRLHEDRRGCSPLEE 351
Score = 113 bits (273), Expect = 3e-25
Identities = 65/187 (34%), Positives = 87/187 (46%), Gaps = 11/187 (5%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLC-HNTDGSYDCLCRTGYE 173
R VNT GS+ C C PG+R R + CA+ C C T + C CR G++
Sbjct: 70 RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQ 129
Query: 174 LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGV 347
L EDG +C C +C C G C C GY+ D AC D++EC G+
Sbjct: 130 LQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDEC-AAGL 188
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARC--VDRD---EC-AQTGRCQAPCRNYAGGY 509
C+N GSF+CVC GY L A+G +C ++ + C A G C C + + G
Sbjct: 189 AQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGP 248
Query: 510 RCDCPVG 530
C CP G
Sbjct: 249 LCTCPRG 255
Score = 101 bits (243), Expect = 1e-21
Identities = 59/177 (33%), Positives = 77/177 (43%), Gaps = 7/177 (3%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
G + C G P G + D EC C C NT GSY C C+ G+ L D
Sbjct: 35 GCYPCHLGQAGYPVSAGDQRPDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRT 94
Query: 195 CRDVDECERDTHTCQQICSN-TEGSYECSCEDGYEKRGDA--CVDINEC-HEEGVCPSPG 362
C ++ C CQ C T + C C G++ + D CV + C + G C
Sbjct: 95 CLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH-- 152
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGRCQAPCRNYAGGYRCDCPVG 530
RC + G RC C GY+L A+G C D DECA +C C N G ++C C G
Sbjct: 153 RCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAG 209
Score = 45.6 bits (103), Expect = 1e-04
Identities = 51/178 (28%), Positives = 70/178 (39%), Gaps = 14/178 (7%)
Frame = +3
Query: 39 CGPGYRPAGRGVRGRDECAVRPPPCDQL---CHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C GY G+ R + CA R C +L C G Y C G C +
Sbjct: 493 CPKGYY--GKHCRKKCNCANRGR-CHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEEC 549
Query: 210 ECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINE-------CHEEGVCPSPGRC 368
+C + HT Q C +GS CSC+ G+ RG+ C E C + CP C
Sbjct: 550 QCVQP-HT--QSCDKRDGS--CSCKAGF--RGERCQAECELGYFGPGCWQACTCPVGVAC 602
Query: 369 VNLLGSFRCVCPRGYRLDAEGARC---VDRDECAQTGRC-QAPCRNYAGGYRCDCPVG 530
++ G CP G++ + G C C+ + C APC G +C CP G
Sbjct: 603 DSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTG--QCRCPPG 658
Score = 41.9 bits (94), Expect = 0.001
Identities = 50/187 (26%), Positives = 69/187 (36%), Gaps = 21/187 (11%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG-ANCRDVD 209
C C PG+ G + + P C C+ + G C +G L E G R
Sbjct: 740 CSCAPGW--TGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQ 797
Query: 210 ECERDTHT--CQQICSNTEG------SYECSCEDGYEKRGDACVDIN-------ECHEEG 344
+C + C+Q C G S C+C G+ RG C +C
Sbjct: 798 QCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGW--RGTFCEHACPAGFFGLDCRSAC 855
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRD---ECAQTGRC--QAPCRNYAGGY 509
C + C + GS C+CP G R +C+ RD C +G C C + G
Sbjct: 856 NCTAGAACDAVNGS--CLCPAGRRGPRCAEKCLPRDVRAGCRHSGGCLNGGLCDPHTG-- 911
Query: 510 RCDCPVG 530
RC CP G
Sbjct: 912 RCLCPAG 918
Score = 37.5 bits (83), Expect = 0.031
Identities = 45/176 (25%), Positives = 60/176 (34%), Gaps = 25/176 (14%)
Frame = +3
Query: 30 RCVCGPGYR------PAGRGVRGRDECAVRPP-PCDQLCHNTDGSYDCLCRTGYELDEDG 188
RC+C G+ P RG G + CA R P CH+ G+ C C G+ G
Sbjct: 912 RCLCPAGWTGDKCQSPCLRGWFG-EACAQRCSCPPGAACHHVTGA--CRCPPGFT----G 964
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSY------ECSCEDGY-----------EKRGDACV 317
+ C R C+Q+C G C C G+ + G C
Sbjct: 965 SGCEQGCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCT 1024
Query: 318 DINECHEEGVC-PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQA 482
+ C + C P G C+ G C RG + G C C G C A
Sbjct: 1025 HVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHA 1080
Score = 30.3 bits (65), Expect = 4.7
Identities = 31/111 (27%), Positives = 40/111 (36%), Gaps = 4/111 (3%)
Frame = +3
Query: 156 CRTGYE--LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINE 329
CR G L DG +C + TC S+ CSC++G C +
Sbjct: 422 CRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNG-----GTCDSVT- 475
Query: 330 CHEEGVCPSPGRCVNLLGSFRCV--CPRGYRLDAEGARCVDRDECAQTGRC 476
G C RC + C CP+GY G C + CA GRC
Sbjct: 476 ----GAC----RCPPGVSGTNCEDGCPKGYY----GKHCRKKCNCANRGRC 514
>AL512413-3|CAH70834.1| 1229|Homo sapiens multiple EGF-like-domains
6 protein.
Length = 1229
Score = 138 bits (333), Expect = 2e-32
Identities = 70/180 (38%), Positives = 89/180 (49%), Gaps = 10/180 (5%)
Frame = +3
Query: 21 GSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
G RC C GY+ A G+ DECA C C NT GS+ C+C GYEL DG
Sbjct: 159 GLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQ 218
Query: 195 C-----RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCP 353
C V+ CE + C CS+T C+C GYE D C+D+++C + C
Sbjct: 219 CYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQ 278
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQT-GRCQAPCRNYAGGYRCDCPVG 530
C N G + C C GYRL A+G C D DECA + G C+ C N AG ++C C G
Sbjct: 279 QV--CTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAG 336
Score = 132 bits (319), Expect = 8e-31
Identities = 73/188 (38%), Positives = 84/188 (44%), Gaps = 9/188 (4%)
Frame = +3
Query: 15 TIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
TI RC C PG++ GR R CA R C C G C C GY+L DG
Sbjct: 116 TITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADG 175
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDI-----NECHEEGV 347
C DVDEC C C NT+GS++C C GYE D C I N C
Sbjct: 176 KACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNG 235
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPV 527
S G C + C CPRGY LD + C+D D+CA + CQ C N GGY C C
Sbjct: 236 GCSHG-CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYA 294
Query: 528 GTVRSPSG 551
G S G
Sbjct: 295 GYRLSADG 302
Score = 116 bits (280), Expect = 4e-26
Identities = 62/159 (38%), Positives = 76/159 (47%), Gaps = 10/159 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRG-------VRGRDECAVRPPPCDQLCHNTDGSYDCLCRTG 167
+NT GSF+CVC GY G + + C C C +T C C G
Sbjct: 196 LNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRG 255
Query: 168 YELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC--VDINEC-HE 338
YELD D C DVD+C D+ CQQ+C+N G YEC C GY D C D++EC
Sbjct: 256 YELDTDQRTCIDVDDCA-DSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASS 314
Query: 339 EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE 455
G C C NL GSF+C C GYRL + C +E
Sbjct: 315 RGGCEH--HCTNLAGSFQCSCEAGYRLHEDRRGCSPLEE 351
Score = 113 bits (273), Expect = 3e-25
Identities = 65/187 (34%), Positives = 87/187 (46%), Gaps = 11/187 (5%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLC-HNTDGSYDCLCRTGYE 173
R VNT GS+ C C PG+R R + CA+ C C T + C CR G++
Sbjct: 70 RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQ 129
Query: 174 LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGV 347
L EDG +C C +C C G C C GY+ D AC D++EC G+
Sbjct: 130 LQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDEC-AAGL 188
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARC--VDRD---EC-AQTGRCQAPCRNYAGGY 509
C+N GSF+CVC GY L A+G +C ++ + C A G C C + + G
Sbjct: 189 AQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGP 248
Query: 510 RCDCPVG 530
C CP G
Sbjct: 249 LCTCPRG 255
Score = 101 bits (243), Expect = 1e-21
Identities = 59/177 (33%), Positives = 77/177 (43%), Gaps = 7/177 (3%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
G + C G P G + D EC C C NT GSY C C+ G+ L D
Sbjct: 35 GCYPCHLGQAGYPVSAGDQRPDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRT 94
Query: 195 CRDVDECERDTHTCQQICSN-TEGSYECSCEDGYEKRGDA--CVDINEC-HEEGVCPSPG 362
C ++ C CQ C T + C C G++ + D CV + C + G C
Sbjct: 95 CLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH-- 152
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGRCQAPCRNYAGGYRCDCPVG 530
RC + G RC C GY+L A+G C D DECA +C C N G ++C C G
Sbjct: 153 RCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAG 209
Score = 45.6 bits (103), Expect = 1e-04
Identities = 51/178 (28%), Positives = 70/178 (39%), Gaps = 14/178 (7%)
Frame = +3
Query: 39 CGPGYRPAGRGVRGRDECAVRPPPCDQL---CHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C GY G+ R + CA R C +L C G Y C G C +
Sbjct: 493 CPKGYY--GKHCRKKCNCANRGR-CHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEEC 549
Query: 210 ECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINE-------CHEEGVCPSPGRC 368
+C + HT Q C +GS CSC+ G+ RG+ C E C + CP C
Sbjct: 550 QCVQP-HT--QSCDKRDGS--CSCKAGF--RGERCQAECELGYFGPGCWQACTCPVGVAC 602
Query: 369 VNLLGSFRCVCPRGYRLDAEGARC---VDRDECAQTGRC-QAPCRNYAGGYRCDCPVG 530
++ G CP G++ + G C C+ + C APC G +C CP G
Sbjct: 603 DSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTG--QCRCPPG 658
Score = 41.9 bits (94), Expect = 0.001
Identities = 50/187 (26%), Positives = 69/187 (36%), Gaps = 21/187 (11%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG-ANCRDVD 209
C C PG+ G + + P C C+ + G C +G L E G R
Sbjct: 740 CSCAPGW--TGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQ 797
Query: 210 ECERDTHT--CQQICSNTEG------SYECSCEDGYEKRGDACVDIN-------ECHEEG 344
+C + C+Q C G S C+C G+ RG C +C
Sbjct: 798 QCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGW--RGTFCEHACPAGFFGLDCRSAC 855
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRD---ECAQTGRC--QAPCRNYAGGY 509
C + C + GS C+CP G R +C+ RD C +G C C + G
Sbjct: 856 NCTAGAACDAVNGS--CLCPAGRRGPRCAEKCLPRDVRAGCRHSGGCLNGGLCDPHTG-- 911
Query: 510 RCDCPVG 530
RC CP G
Sbjct: 912 RCLCPAG 918
Score = 37.5 bits (83), Expect = 0.031
Identities = 45/176 (25%), Positives = 60/176 (34%), Gaps = 25/176 (14%)
Frame = +3
Query: 30 RCVCGPGYR------PAGRGVRGRDECAVRPP-PCDQLCHNTDGSYDCLCRTGYELDEDG 188
RC+C G+ P RG G + CA R P CH+ G+ C C G+ G
Sbjct: 912 RCLCPAGWTGDKCQSPCLRGWFG-EACAQRCSCPPGAACHHVTGA--CRCPPGFT----G 964
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSY------ECSCEDGY-----------EKRGDACV 317
+ C R C+Q+C G C C G+ + G C
Sbjct: 965 SGCEQGCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCT 1024
Query: 318 DINECHEEGVC-PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQA 482
+ C + C P G C+ G C RG + G C C G C A
Sbjct: 1025 HVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHA 1080
Score = 30.3 bits (65), Expect = 4.7
Identities = 31/111 (27%), Positives = 40/111 (36%), Gaps = 4/111 (3%)
Frame = +3
Query: 156 CRTGYE--LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINE 329
CR G L DG +C + TC S+ CSC++G C +
Sbjct: 422 CRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNG-----GTCDSVT- 475
Query: 330 CHEEGVCPSPGRCVNLLGSFRCV--CPRGYRLDAEGARCVDRDECAQTGRC 476
G C RC + C CP+GY G C + CA GRC
Sbjct: 476 ----GAC----RCPPGVSGTNCEDGCPKGYY----GKHCRKKCNCANRGRC 514
>AB231860-1|BAE19678.1| 1640|Homo sapiens hypothetical protein
protein.
Length = 1640
Score = 138 bits (333), Expect = 2e-32
Identities = 70/180 (38%), Positives = 89/180 (49%), Gaps = 10/180 (5%)
Frame = +3
Query: 21 GSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
G RC C GY+ A G+ DECA C C NT GS+ C+C GYEL DG
Sbjct: 339 GLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQ 398
Query: 195 C-----RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCP 353
C V+ CE + C CS+T C+C GYE D C+D+++C + C
Sbjct: 399 CYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQ 458
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQT-GRCQAPCRNYAGGYRCDCPVG 530
C N G + C C GYRL A+G C D DECA + G C+ C N AG ++C C G
Sbjct: 459 QV--CTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAG 516
Score = 132 bits (319), Expect = 8e-31
Identities = 73/188 (38%), Positives = 84/188 (44%), Gaps = 9/188 (4%)
Frame = +3
Query: 15 TIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
TI RC C PG++ GR R CA R C C G C C GY+L DG
Sbjct: 296 TITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADG 355
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDI-----NECHEEGV 347
C DVDEC C C NT+GS++C C GYE D C I N C
Sbjct: 356 KACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNG 415
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPV 527
S G C + C CPRGY LD + C+D D+CA + CQ C N GGY C C
Sbjct: 416 GCSHG-CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYA 474
Query: 528 GTVRSPSG 551
G S G
Sbjct: 475 GYRLSADG 482
Score = 116 bits (280), Expect = 4e-26
Identities = 62/159 (38%), Positives = 76/159 (47%), Gaps = 10/159 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRG-------VRGRDECAVRPPPCDQLCHNTDGSYDCLCRTG 167
+NT GSF+CVC GY G + + C C C +T C C G
Sbjct: 376 LNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRG 435
Query: 168 YELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC--VDINEC-HE 338
YELD D C DVD+C D+ CQQ+C+N G YEC C GY D C D++EC
Sbjct: 436 YELDTDQRTCIDVDDCA-DSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASS 494
Query: 339 EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE 455
G C C NL GSF+C C GYRL + C +E
Sbjct: 495 RGGCEH--HCTNLAGSFQCSCEAGYRLHEDRRGCSPLEE 531
Score = 113 bits (273), Expect = 3e-25
Identities = 65/187 (34%), Positives = 87/187 (46%), Gaps = 11/187 (5%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLC-HNTDGSYDCLCRTGYE 173
R VNT GS+ C C PG+R R + CA+ C C T + C CR G++
Sbjct: 250 RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQ 309
Query: 174 LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGV 347
L EDG +C C +C C G C C GY+ D AC D++EC G+
Sbjct: 310 LQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDEC-AAGL 368
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARC--VDRD---EC-AQTGRCQAPCRNYAGGY 509
C+N GSF+CVC GY L A+G +C ++ + C A G C C + + G
Sbjct: 369 AQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGP 428
Query: 510 RCDCPVG 530
C CP G
Sbjct: 429 LCTCPRG 435
Score = 104 bits (250), Expect = 2e-22
Identities = 59/171 (34%), Positives = 77/171 (45%), Gaps = 5/171 (2%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDE 212
C C PG++ R DEC C C NT GSY C C+ G+ L D C ++
Sbjct: 222 CHCPPGFQ-GPRCQYDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINS 280
Query: 213 CERDTHTCQQICSN-TEGSYECSCEDGYEKRGDA--CVDINEC-HEEGVCPSPGRCVNLL 380
C CQ C T + C C G++ + D CV + C + G C RC +
Sbjct: 281 CALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH--RCQVVR 338
Query: 381 GSFRCVCPRGYRLDAEGARCVDRDECAQ-TGRCQAPCRNYAGGYRCDCPVG 530
G RC C GY+L A+G C D DECA +C C N G ++C C G
Sbjct: 339 GLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAG 389
Score = 46.4 bits (105), Expect = 7e-05
Identities = 42/154 (27%), Positives = 58/154 (37%), Gaps = 18/154 (11%)
Frame = +3
Query: 123 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSY------ECSCE 284
C +GS CLC G G C + H C Q C+ G+ +C C
Sbjct: 1043 CDAVNGS--CLCPAGRR----GPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCA 1096
Query: 285 DGYEKRGDACVDI-------NECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCV 443
G+ G +C+ + C +C + G C + G C CP G+ A C+
Sbjct: 1097 PGW--MGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSG--HCACPEGWAGLACEKECL 1152
Query: 444 DRD---ECAQTGRC--QAPCRNYAGGYRCDCPVG 530
RD C +G C C + G RC CP G
Sbjct: 1153 PRDVRAGCRHSGGCLNGGLCDPHTG--RCLCPAG 1184
Score = 45.6 bits (103), Expect = 1e-04
Identities = 51/178 (28%), Positives = 70/178 (39%), Gaps = 14/178 (7%)
Frame = +3
Query: 39 CGPGYRPAGRGVRGRDECAVRPPPCDQL---CHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C GY G+ R + CA R C +L C G Y C G C +
Sbjct: 673 CPKGYY--GKHCRKKCNCANRGR-CHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEEC 729
Query: 210 ECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINE-------CHEEGVCPSPGRC 368
+C + HT Q C +GS CSC+ G+ RG+ C E C + CP C
Sbjct: 730 QCVQP-HT--QSCDKRDGS--CSCKAGF--RGERCQAECELGYFGPGCWQACTCPVGVAC 782
Query: 369 VNLLGSFRCVCPRGYRLDAEGARC---VDRDECAQTGRC-QAPCRNYAGGYRCDCPVG 530
++ G CP G++ + G C C+ + C APC G +C CP G
Sbjct: 783 DSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTG--QCRCPPG 838
Score = 41.9 bits (94), Expect = 0.001
Identities = 40/153 (26%), Positives = 50/153 (32%), Gaps = 3/153 (1%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAV--RPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDV 206
C C PG PA G CA P C Q C G Y C E C +
Sbjct: 1250 CQC-PGENPACHPATGTCSCAAGYHGPSCQQRC--PPGRYGPGC-------EQLCGCLNG 1299
Query: 207 DECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVC-PSPGRCVNLLG 383
C+ T C+ C +C+ + G C + C + C P G C+ G
Sbjct: 1300 GSCDAATGACR--CPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPG 1357
Query: 384 SFRCVCPRGYRLDAEGARCVDRDECAQTGRCQA 482
C RG + G C C G C A
Sbjct: 1358 RAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHA 1390
Score = 39.1 bits (87), Expect = 0.010
Identities = 45/150 (30%), Positives = 56/150 (37%), Gaps = 13/150 (8%)
Frame = +3
Query: 120 LCHNTDGSYDC-LCRTGYELD------EDGANCRDVDECERDTHTCQQI---CSNTEGSY 269
LCH ++GS C L TG + GA C C ++ TC+ C G Y
Sbjct: 1387 LCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNS-TCEPATGTCRCGPGFY 1445
Query: 270 ECSCEDGYEK--RGDACVDINECHEEGVC-PSPGRCVNLLGSFRCVCPRGYRLDAEGARC 440
+CE G C + C C P GRC+ G C RG + G C
Sbjct: 1446 GQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGC 1505
Query: 441 VDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
R +C G APC G C CP G
Sbjct: 1506 HQRCDC-DGG---APCDPVTG--LCLCPPG 1529
Score = 30.3 bits (65), Expect = 4.7
Identities = 31/111 (27%), Positives = 40/111 (36%), Gaps = 4/111 (3%)
Frame = +3
Query: 156 CRTGYE--LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINE 329
CR G L DG +C + TC S+ CSC++G C +
Sbjct: 602 CRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNG-----GTCDSVT- 655
Query: 330 CHEEGVCPSPGRCVNLLGSFRCV--CPRGYRLDAEGARCVDRDECAQTGRC 476
G C RC + C CP+GY G C + CA GRC
Sbjct: 656 ----GAC----RCPPGVSGTNCEDGCPKGYY----GKHCRKKCNCANRGRC 694
>AB011539-1|BAA32467.2| 1246|Homo sapiens MEGF6 protein.
Length = 1246
Score = 138 bits (333), Expect = 2e-32
Identities = 70/180 (38%), Positives = 89/180 (49%), Gaps = 10/180 (5%)
Frame = +3
Query: 21 GSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
G RC C GY+ A G+ DECA C C NT GS+ C+C GYEL DG
Sbjct: 176 GLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQ 235
Query: 195 C-----RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCP 353
C V+ CE + C CS+T C+C GYE D C+D+++C + C
Sbjct: 236 CYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQ 295
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQT-GRCQAPCRNYAGGYRCDCPVG 530
C N G + C C GYRL A+G C D DECA + G C+ C N AG ++C C G
Sbjct: 296 QV--CTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAG 353
Score = 132 bits (319), Expect = 8e-31
Identities = 73/188 (38%), Positives = 84/188 (44%), Gaps = 9/188 (4%)
Frame = +3
Query: 15 TIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
TI RC C PG++ GR R CA R C C G C C GY+L DG
Sbjct: 133 TITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADG 192
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDI-----NECHEEGV 347
C DVDEC C C NT+GS++C C GYE D C I N C
Sbjct: 193 KACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNG 252
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPV 527
S G C + C CPRGY LD + C+D D+CA + CQ C N GGY C C
Sbjct: 253 GCSHG-CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYA 311
Query: 528 GTVRSPSG 551
G S G
Sbjct: 312 GYRLSADG 319
Score = 116 bits (280), Expect = 4e-26
Identities = 62/159 (38%), Positives = 76/159 (47%), Gaps = 10/159 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRG-------VRGRDECAVRPPPCDQLCHNTDGSYDCLCRTG 167
+NT GSF+CVC GY G + + C C C +T C C G
Sbjct: 213 LNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRG 272
Query: 168 YELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC--VDINEC-HE 338
YELD D C DVD+C D+ CQQ+C+N G YEC C GY D C D++EC
Sbjct: 273 YELDTDQRTCIDVDDCA-DSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASS 331
Query: 339 EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE 455
G C C NL GSF+C C GYRL + C +E
Sbjct: 332 RGGCEH--HCTNLAGSFQCSCEAGYRLHEDRRGCSPLEE 368
Score = 113 bits (273), Expect = 3e-25
Identities = 65/187 (34%), Positives = 87/187 (46%), Gaps = 11/187 (5%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLC-HNTDGSYDCLCRTGYE 173
R VNT GS+ C C PG+R R + CA+ C C T + C CR G++
Sbjct: 87 RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQ 146
Query: 174 LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGV 347
L EDG +C C +C C G C C GY+ D AC D++EC G+
Sbjct: 147 LQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDEC-AAGL 205
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARC--VDRD---EC-AQTGRCQAPCRNYAGGY 509
C+N GSF+CVC GY L A+G +C ++ + C A G C C + + G
Sbjct: 206 AQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGP 265
Query: 510 RCDCPVG 530
C CP G
Sbjct: 266 LCTCPRG 272
Score = 101 bits (243), Expect = 1e-21
Identities = 59/177 (33%), Positives = 77/177 (43%), Gaps = 7/177 (3%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
G + C G P G + D EC C C NT GSY C C+ G+ L D
Sbjct: 52 GCYPCHLGQAGYPVSAGDQRPDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRT 111
Query: 195 CRDVDECERDTHTCQQICSN-TEGSYECSCEDGYEKRGDA--CVDINEC-HEEGVCPSPG 362
C ++ C CQ C T + C C G++ + D CV + C + G C
Sbjct: 112 CLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH-- 169
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGRCQAPCRNYAGGYRCDCPVG 530
RC + G RC C GY+L A+G C D DECA +C C N G ++C C G
Sbjct: 170 RCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAG 226
Score = 45.6 bits (103), Expect = 1e-04
Identities = 51/178 (28%), Positives = 70/178 (39%), Gaps = 14/178 (7%)
Frame = +3
Query: 39 CGPGYRPAGRGVRGRDECAVRPPPCDQL---CHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C GY G+ R + CA R C +L C G Y C G C +
Sbjct: 510 CPKGYY--GKHCRKKCNCANRGR-CHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEEC 566
Query: 210 ECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINE-------CHEEGVCPSPGRC 368
+C + HT Q C +GS CSC+ G+ RG+ C E C + CP C
Sbjct: 567 QCVQP-HT--QSCDKRDGS--CSCKAGF--RGERCQAECELGYFGPGCWQACTCPVGVAC 619
Query: 369 VNLLGSFRCVCPRGYRLDAEGARC---VDRDECAQTGRC-QAPCRNYAGGYRCDCPVG 530
++ G CP G++ + G C C+ + C APC G +C CP G
Sbjct: 620 DSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTG--QCRCPPG 675
Score = 44.0 bits (99), Expect = 4e-04
Identities = 50/187 (26%), Positives = 70/187 (37%), Gaps = 21/187 (11%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG-ANCRDVD 209
C C PG+ G + + P C C+ + G C +G L E G R
Sbjct: 757 CSCAPGW--TGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQ 814
Query: 210 ECERDTHT--CQQICSNTEG------SYECSCEDGYEKRGDACVDIN-------ECHEEG 344
+C + C+Q+C G S C+C G+ RG C +C
Sbjct: 815 QCPQGHFGPGCEQLCQCQHGAACDHVSGACTCPAGW--RGTFCEHACPAGFFGLDCRSAC 872
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRD---ECAQTGRC--QAPCRNYAGGY 509
C + C + GS C+CP G R +C+ RD C +G C C + G
Sbjct: 873 NCTAGAACDAVNGS--CLCPAGRRGPRCAEKCLPRDVRAGCRHSGGCLNGGLCDPHTG-- 928
Query: 510 RCDCPVG 530
RC CP G
Sbjct: 929 RCLCPAG 935
Score = 37.1 bits (82), Expect = 0.041
Identities = 45/176 (25%), Positives = 60/176 (34%), Gaps = 25/176 (14%)
Frame = +3
Query: 30 RCVCGPGYR------PAGRGVRGRDECAVRPP-PCDQLCHNTDGSYDCLCRTGYELDEDG 188
RC+C G+ P RG G + CA R P CH+ G+ C C G+ G
Sbjct: 929 RCLCPAGWTGDKCQSPCLRGWFG-EACAQRCSCPPAAACHHVTGA--CRCPPGFT----G 981
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSY------ECSCEDGY-----------EKRGDACV 317
+ C R C+Q+C G C C G+ + G C
Sbjct: 982 SGCEQGCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCT 1041
Query: 318 DINECHEEGVC-PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQA 482
+ C + C P G C+ G C RG + G C C G C A
Sbjct: 1042 HVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHA 1097
Score = 30.3 bits (65), Expect = 4.7
Identities = 31/111 (27%), Positives = 40/111 (36%), Gaps = 4/111 (3%)
Frame = +3
Query: 156 CRTGYE--LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINE 329
CR G L DG +C + TC S+ CSC++G C +
Sbjct: 439 CRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNG-----GTCDSVT- 492
Query: 330 CHEEGVCPSPGRCVNLLGSFRCV--CPRGYRLDAEGARCVDRDECAQTGRC 476
G C RC + C CP+GY G C + CA GRC
Sbjct: 493 ----GAC----RCPPGVSGTNCEDGCPKGYY----GKHCRKKCNCANRGRC 531
>CR457140-1|CAG33421.1| 448|Homo sapiens FBLN5 protein.
Length = 448
Score = 136 bits (330), Expect = 4e-32
Identities = 68/156 (43%), Positives = 83/156 (53%), Gaps = 5/156 (3%)
Frame = +3
Query: 84 DECAVRPPPCD--QLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNT 257
DECA C+ Q+C NT+G Y C C GY L E C D+DEC CQQ+C+N
Sbjct: 129 DECATDSHQCNPTQICINTEGGYTCSCTDGYWLLE--GQCLDIDECRYG--YCQQLCANV 184
Query: 258 EGSYECSCEDGY--EKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEG 431
GSY C+C G+ + G +C D+NEC E C CVN GSF C C GY L+ +G
Sbjct: 185 PGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQ--TCVNTYGSFICRCDPGYELEEDG 242
Query: 432 ARCVDRDECA-QTGRCQAPCRNYAGGYRCDCPVGTV 536
C D DEC+ CQ C N G Y C CP G +
Sbjct: 243 VHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYI 278
Score = 135 bits (326), Expect = 1e-31
Identities = 72/179 (40%), Positives = 93/179 (51%), Gaps = 6/179 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+NT G + C C GY DEC R C QLC N GSY C C G+ L+EDG
Sbjct: 145 INTEGGYTCSCTDGYWLLEGQCLDIDEC--RYGYCQQLCANVPGSYSCTCNPGFTLNEDG 202
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINEC-HEEGVCPSP 359
+C+DV+EC + + C Q C NT GS+ C C+ GYE D C D++EC E +C
Sbjct: 203 RSCQDVNECATE-NPCVQTCVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQH- 260
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA---QTGRCQAPCRNYAGGYRCDCPV 527
CVN G++ C CP GY L + C D +EC T Q C N GG++C P+
Sbjct: 261 -ECVNQPGTYFCSCPPGYILLDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPI 318
Score = 120 bits (288), Expect = 4e-27
Identities = 57/128 (44%), Positives = 70/128 (54%), Gaps = 2/128 (1%)
Frame = +3
Query: 153 LCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRGDACVDIN 326
+CR GY++DE C DVDEC D+H C QIC NTEG Y CSC DGY C+DI+
Sbjct: 112 ICRFGYQMDESN-QCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLDID 170
Query: 327 ECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGG 506
EC G C C N+ GS+ C C G+ L+ +G C D +ECA C C N G
Sbjct: 171 ECRY-GYCQQ--LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGS 227
Query: 507 YRCDCPVG 530
+ C C G
Sbjct: 228 FICRCDPG 235
Score = 71.3 bits (167), Expect = 2e-12
Identities = 50/162 (30%), Positives = 69/162 (42%), Gaps = 6/162 (3%)
Frame = +3
Query: 84 DECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNT 257
DEC P C D +C N +G Y C+ RT +N + +
Sbjct: 44 DECRTIPEACRGDMMCVNQNGGYLCIPRTNPVYRGPYSNPYSTPYSGPYPAAAPPLSAPN 103
Query: 258 EG--SYECSCEDGYEK-RGDACVDINECHEEGVCPSPGR-CVNLLGSFRCVCPRGYRLDA 425
S C GY+ + CVD++EC + +P + C+N G + C C GY L
Sbjct: 104 YPTISRPLICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWL-L 162
Query: 426 EGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVRSPSG 551
EG +C+D DEC + G CQ C N G Y C C G + G
Sbjct: 163 EG-QCLDIDEC-RYGYCQQLCANVPGSYSCTCNPGFTLNEDG 202
Score = 65.7 bits (153), Expect = 1e-10
Identities = 46/146 (31%), Positives = 62/146 (42%), Gaps = 9/146 (6%)
Frame = +3
Query: 120 LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGY 293
LC + G+ C G++LD C D+DEC C+ +C N G Y C
Sbjct: 15 LCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNP 74
Query: 294 EKRGDACVDINECHEEGVCPS---PGRCVNLLGSFR-CVCPRGYRLDAEGARCVDRDECA 461
RG + + G P+ P N R +C GY++D E +CVD DECA
Sbjct: 75 VYRGPYSNPYSTPY-SGPYPAAAPPLSAPNYPTISRPLICRFGYQMD-ESNQCVDVDECA 132
Query: 462 -QTGRCQAP--CRNYAGGYRCDCPVG 530
+ +C C N GGY C C G
Sbjct: 133 TDSHQCNPTQICINTEGGYTCSCTDG 158
>BC022280-1|AAH22280.1| 448|Homo sapiens fibulin 5 protein.
Length = 448
Score = 136 bits (330), Expect = 4e-32
Identities = 68/156 (43%), Positives = 83/156 (53%), Gaps = 5/156 (3%)
Frame = +3
Query: 84 DECAVRPPPCD--QLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNT 257
DECA C+ Q+C NT+G Y C C GY L E C D+DEC CQQ+C+N
Sbjct: 129 DECATDSHQCNPTQICINTEGGYTCSCTDGYWLLE--GQCLDIDECRYG--YCQQLCANV 184
Query: 258 EGSYECSCEDGY--EKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEG 431
GSY C+C G+ + G +C D+NEC E C CVN GSF C C GY L+ +G
Sbjct: 185 PGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQ--TCVNTYGSFICRCDPGYELEEDG 242
Query: 432 ARCVDRDECA-QTGRCQAPCRNYAGGYRCDCPVGTV 536
C D DEC+ CQ C N G Y C CP G +
Sbjct: 243 VHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYI 278
Score = 135 bits (326), Expect = 1e-31
Identities = 72/179 (40%), Positives = 93/179 (51%), Gaps = 6/179 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+NT G + C C GY DEC R C QLC N GSY C C G+ L+EDG
Sbjct: 145 INTEGGYTCSCTDGYWLLEGQCLDIDEC--RYGYCQQLCANVPGSYSCTCNPGFTLNEDG 202
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINEC-HEEGVCPSP 359
+C+DV+EC + + C Q C NT GS+ C C+ GYE D C D++EC E +C
Sbjct: 203 RSCQDVNECATE-NPCVQTCVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQH- 260
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA---QTGRCQAPCRNYAGGYRCDCPV 527
CVN G++ C CP GY L + C D +EC T Q C N GG++C P+
Sbjct: 261 -ECVNQPGTYFCSCPPGYILLDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPI 318
Score = 120 bits (288), Expect = 4e-27
Identities = 57/128 (44%), Positives = 70/128 (54%), Gaps = 2/128 (1%)
Frame = +3
Query: 153 LCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRGDACVDIN 326
+CR GY++DE C DVDEC D+H C QIC NTEG Y CSC DGY C+DI+
Sbjct: 112 ICRFGYQMDESN-QCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLDID 170
Query: 327 ECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGG 506
EC G C C N+ GS+ C C G+ L+ +G C D +ECA C C N G
Sbjct: 171 ECRY-GYCQQ--LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGS 227
Query: 507 YRCDCPVG 530
+ C C G
Sbjct: 228 FICRCDPG 235
Score = 71.3 bits (167), Expect = 2e-12
Identities = 50/162 (30%), Positives = 69/162 (42%), Gaps = 6/162 (3%)
Frame = +3
Query: 84 DECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNT 257
DEC P C D +C N +G Y C+ RT +N + +
Sbjct: 44 DECRTIPEACRGDMMCVNQNGGYLCIPRTNPVYRGPYSNPYSTPYSGPYPAAAPPLSAPN 103
Query: 258 EG--SYECSCEDGYEK-RGDACVDINECHEEGVCPSPGR-CVNLLGSFRCVCPRGYRLDA 425
S C GY+ + CVD++EC + +P + C+N G + C C GY L
Sbjct: 104 YPTISRPLICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWL-L 162
Query: 426 EGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVRSPSG 551
EG +C+D DEC + G CQ C N G Y C C G + G
Sbjct: 163 EG-QCLDIDEC-RYGYCQQLCANVPGSYSCTCNPGFTLNEDG 202
Score = 65.7 bits (153), Expect = 1e-10
Identities = 46/146 (31%), Positives = 62/146 (42%), Gaps = 9/146 (6%)
Frame = +3
Query: 120 LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGY 293
LC + G+ C G++LD C D+DEC C+ +C N G Y C
Sbjct: 15 LCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNP 74
Query: 294 EKRGDACVDINECHEEGVCPS---PGRCVNLLGSFR-CVCPRGYRLDAEGARCVDRDECA 461
RG + + G P+ P N R +C GY++D E +CVD DECA
Sbjct: 75 VYRGPYSNPYSTPY-SGPYPAAAPPLSAPNYPTISRPLICRFGYQMD-ESNQCVDVDECA 132
Query: 462 -QTGRCQAP--CRNYAGGYRCDCPVG 530
+ +C C N GGY C C G
Sbjct: 133 TDSHQCNPTQICINTEGGYTCSCTDG 158
>AJ133490-1|CAB38568.1| 448|Homo sapiens fibulin-5 protein.
Length = 448
Score = 136 bits (330), Expect = 4e-32
Identities = 68/156 (43%), Positives = 83/156 (53%), Gaps = 5/156 (3%)
Frame = +3
Query: 84 DECAVRPPPCD--QLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNT 257
DECA C+ Q+C NT+G Y C C GY L E C D+DEC CQQ+C+N
Sbjct: 129 DECATDSHQCNPTQICINTEGGYTCSCTDGYWLLE--GQCLDIDECRYG--YCQQLCANV 184
Query: 258 EGSYECSCEDGY--EKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEG 431
GSY C+C G+ + G +C D+NEC E C CVN GSF C C GY L+ +G
Sbjct: 185 PGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQ--TCVNTYGSFICRCDPGYELEEDG 242
Query: 432 ARCVDRDECA-QTGRCQAPCRNYAGGYRCDCPVGTV 536
C D DEC+ CQ C N G Y C CP G +
Sbjct: 243 VHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYI 278
Score = 135 bits (326), Expect = 1e-31
Identities = 72/179 (40%), Positives = 93/179 (51%), Gaps = 6/179 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+NT G + C C GY DEC R C QLC N GSY C C G+ L+EDG
Sbjct: 145 INTEGGYTCSCTDGYWLLEGQCLDIDEC--RYGYCQQLCANVPGSYSCTCNPGFTLNEDG 202
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINEC-HEEGVCPSP 359
+C+DV+EC + + C Q C NT GS+ C C+ GYE D C D++EC E +C
Sbjct: 203 RSCQDVNECATE-NPCVQTCVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQH- 260
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA---QTGRCQAPCRNYAGGYRCDCPV 527
CVN G++ C CP GY L + C D +EC T Q C N GG++C P+
Sbjct: 261 -ECVNQPGTYFCSCPPGYILLDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPI 318
Score = 120 bits (288), Expect = 4e-27
Identities = 57/128 (44%), Positives = 70/128 (54%), Gaps = 2/128 (1%)
Frame = +3
Query: 153 LCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRGDACVDIN 326
+CR GY++DE C DVDEC D+H C QIC NTEG Y CSC DGY C+DI+
Sbjct: 112 ICRFGYQMDESN-QCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLDID 170
Query: 327 ECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGG 506
EC G C C N+ GS+ C C G+ L+ +G C D +ECA C C N G
Sbjct: 171 ECRY-GYCQQ--LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGS 227
Query: 507 YRCDCPVG 530
+ C C G
Sbjct: 228 FICRCDPG 235
Score = 71.3 bits (167), Expect = 2e-12
Identities = 50/162 (30%), Positives = 69/162 (42%), Gaps = 6/162 (3%)
Frame = +3
Query: 84 DECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNT 257
DEC P C D +C N +G Y C+ RT +N + +
Sbjct: 44 DECRTIPEACRGDMMCVNQNGGYLCIPRTNPVYRGPYSNPYSTPYSGPYPAAAPPLSAPN 103
Query: 258 EG--SYECSCEDGYEK-RGDACVDINECHEEGVCPSPGR-CVNLLGSFRCVCPRGYRLDA 425
S C GY+ + CVD++EC + +P + C+N G + C C GY L
Sbjct: 104 YPTISRPLICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWL-L 162
Query: 426 EGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVRSPSG 551
EG +C+D DEC + G CQ C N G Y C C G + G
Sbjct: 163 EG-QCLDIDEC-RYGYCQQLCANVPGSYSCTCNPGFTLNEDG 202
Score = 65.7 bits (153), Expect = 1e-10
Identities = 46/146 (31%), Positives = 62/146 (42%), Gaps = 9/146 (6%)
Frame = +3
Query: 120 LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGY 293
LC + G+ C G++LD C D+DEC C+ +C N G Y C
Sbjct: 15 LCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNP 74
Query: 294 EKRGDACVDINECHEEGVCPS---PGRCVNLLGSFR-CVCPRGYRLDAEGARCVDRDECA 461
RG + + G P+ P N R +C GY++D E +CVD DECA
Sbjct: 75 VYRGPYSNPYSTPY-SGPYPAAAPPLSAPNYPTISRPLICRFGYQMD-ESNQCVDVDECA 132
Query: 462 -QTGRCQAP--CRNYAGGYRCDCPVG 530
+ +C C N GGY C C G
Sbjct: 133 TDSHQCNPTQICINTEGGYTCSCTDG 158
>AF112152-1|AAD41768.1| 448|Homo sapiens developmental arteries and
neural crest EGF-like protein protein.
Length = 448
Score = 136 bits (330), Expect = 4e-32
Identities = 68/156 (43%), Positives = 83/156 (53%), Gaps = 5/156 (3%)
Frame = +3
Query: 84 DECAVRPPPCD--QLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNT 257
DECA C+ Q+C NT+G Y C C GY L E C D+DEC CQQ+C+N
Sbjct: 129 DECATDSHQCNPTQICINTEGGYTCSCTDGYWLLE--GQCLDIDECRYG--YCQQLCANV 184
Query: 258 EGSYECSCEDGY--EKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEG 431
GSY C+C G+ + G +C D+NEC E C CVN GSF C C GY L+ +G
Sbjct: 185 PGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQ--TCVNTYGSFICRCDPGYELEEDG 242
Query: 432 ARCVDRDECA-QTGRCQAPCRNYAGGYRCDCPVGTV 536
C D DEC+ CQ C N G Y C CP G +
Sbjct: 243 VHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYI 278
Score = 135 bits (326), Expect = 1e-31
Identities = 72/179 (40%), Positives = 93/179 (51%), Gaps = 6/179 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+NT G + C C GY DEC R C QLC N GSY C C G+ L+EDG
Sbjct: 145 INTEGGYTCSCTDGYWLLEGQCLDIDEC--RYGYCQQLCANVPGSYSCTCNPGFTLNEDG 202
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINEC-HEEGVCPSP 359
+C+DV+EC + + C Q C NT GS+ C C+ GYE D C D++EC E +C
Sbjct: 203 RSCQDVNECATE-NPCVQTCVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQH- 260
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA---QTGRCQAPCRNYAGGYRCDCPV 527
CVN G++ C CP GY L + C D +EC T Q C N GG++C P+
Sbjct: 261 -ECVNQPGTYFCSCPPGYILLDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPI 318
Score = 120 bits (288), Expect = 4e-27
Identities = 57/128 (44%), Positives = 70/128 (54%), Gaps = 2/128 (1%)
Frame = +3
Query: 153 LCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRGDACVDIN 326
+CR GY++DE C DVDEC D+H C QIC NTEG Y CSC DGY C+DI+
Sbjct: 112 ICRFGYQMDESN-QCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLDID 170
Query: 327 ECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGG 506
EC G C C N+ GS+ C C G+ L+ +G C D +ECA C C N G
Sbjct: 171 ECRY-GYCQQ--LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGS 227
Query: 507 YRCDCPVG 530
+ C C G
Sbjct: 228 FICRCDPG 235
Score = 71.3 bits (167), Expect = 2e-12
Identities = 50/162 (30%), Positives = 69/162 (42%), Gaps = 6/162 (3%)
Frame = +3
Query: 84 DECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNT 257
DEC P C D +C N +G Y C+ RT +N + +
Sbjct: 44 DECRTIPEACRGDMMCVNQNGGYLCIPRTNPVYRGPYSNPYSTPYSGPYPAAAPPLSAPN 103
Query: 258 EG--SYECSCEDGYEK-RGDACVDINECHEEGVCPSPGR-CVNLLGSFRCVCPRGYRLDA 425
S C GY+ + CVD++EC + +P + C+N G + C C GY L
Sbjct: 104 YPTISRPLICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWL-L 162
Query: 426 EGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVRSPSG 551
EG +C+D DEC + G CQ C N G Y C C G + G
Sbjct: 163 EG-QCLDIDEC-RYGYCQQLCANVPGSYSCTCNPGFTLNEDG 202
Score = 65.7 bits (153), Expect = 1e-10
Identities = 46/146 (31%), Positives = 62/146 (42%), Gaps = 9/146 (6%)
Frame = +3
Query: 120 LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGY 293
LC + G+ C G++LD C D+DEC C+ +C N G Y C
Sbjct: 15 LCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNP 74
Query: 294 EKRGDACVDINECHEEGVCPS---PGRCVNLLGSFR-CVCPRGYRLDAEGARCVDRDECA 461
RG + + G P+ P N R +C GY++D E +CVD DECA
Sbjct: 75 VYRGPYSNPYSTPY-SGPYPAAAPPLSAPNYPTISRPLICRFGYQMD-ESNQCVDVDECA 132
Query: 462 -QTGRCQAP--CRNYAGGYRCDCPVG 530
+ +C C N GGY C C G
Sbjct: 133 TDSHQCNPTQICINTEGGYTCSCTDG 158
>BC022497-1|AAH22497.1| 683|Homo sapiens fibulin 1 protein.
Length = 683
Score = 135 bits (327), Expect = 8e-32
Identities = 83/195 (42%), Positives = 100/195 (51%), Gaps = 15/195 (7%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPP-CDQLCHNTDGSYDCLCRTGYE 173
R VN+ GSFRC C GY G R +EC P C C NT GSY C C G+
Sbjct: 372 RCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFR 431
Query: 174 LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR---GDACVDINECH-EE 341
L DG +C D++EC + C Q C+N GSY+C C GY+ G C DI+EC
Sbjct: 432 LSVDGRSCEDINEC--SSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPT 489
Query: 342 GVCPSPGRCVNLLGSFRCVCP-RGYRLDAEGARCVDRDECAQTG--RC--QAPCRNYAGG 506
G RC+N+ GSF+C CP GYRL G+ C D DEC TG C C N GG
Sbjct: 490 GGHICSYRCINIPGSFQCSCPSSGYRLAPNGSNCQDIDECV-TGIHNCSINETCFNIQGG 548
Query: 507 YRC---DCPVGTVRS 542
+RC +CP RS
Sbjct: 549 FRCLAFECPENYRRS 563
Score = 124 bits (300), Expect = 2e-28
Identities = 81/204 (39%), Positives = 98/204 (48%), Gaps = 23/204 (11%)
Frame = +3
Query: 9 VNTIGSFRCV----CGPGYR-PAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCL---- 155
+NT+GSFRC CG GY + DEC C D +C NT GS+ C
Sbjct: 234 INTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 293
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-----SCEDGYE--KRGD 308
C++G+ D G NC D++EC + C C NTEGSY C +C GY + G
Sbjct: 294 CKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 309 ACVDINECHEEGV-CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGR-CQ 479
CVD++EC C RCVN GSFRC C GY D CVD +EC + GR C
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG 412
Query: 480 APCRNYAGGYRCDCPVGTVRSPSG 551
C N G Y C C VG S G
Sbjct: 413 HKCENTLGSYLCSCSVGFRLSVDG 436
Score = 122 bits (293), Expect = 1e-27
Identities = 70/168 (41%), Positives = 86/168 (51%), Gaps = 13/168 (7%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL-DE 182
NT+GS+ C C G+R + GR +EC+ PC Q C N GSY C CR GY+L D
Sbjct: 417 NTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCSQECANVYGSYQCYCRRGYQLSDV 474
Query: 183 DGANCRDVDECERDT--HTCQQICSNTEGSYECSC-EDGYE--KRGDACVDINECHEEGV 347
DG C D+DEC T H C C N GS++CSC GY G C DI+EC G+
Sbjct: 475 DGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGSNCQDIDEC-VTGI 533
Query: 348 --CPSPGRCVNLLGSFRCV---CPRGYRLDAEGARCVDRDECAQTGRC 476
C C N+ G FRC+ CP YR A RC +R C + C
Sbjct: 534 HNCSINETCFNIQGGFRCLAFECPENYRRSA-ATRC-ERLPCHENREC 579
Score = 102 bits (244), Expect = 1e-21
Identities = 62/152 (40%), Positives = 78/152 (51%), Gaps = 16/152 (10%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-- 275
PC Q C +T C C GY+L DG +C DV+EC +H+C+ + C NT GS+ C
Sbjct: 185 PCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 244
Query: 276 --SCEDGYEKRGD-ACVDINECHEEGV--CPSPGRCVNLLGSFRC----VCPRGYRLDAE 428
SC GYE D +C DI+EC E G+ C C N LGSFRC C G+ DA
Sbjct: 245 DSSCGTGYELTEDNSCKDIDEC-ESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL 303
Query: 429 GARCVDRDECAQ-TGRCQA--PCRNYAGGYRC 515
G C+D +EC + C C N G Y C
Sbjct: 304 G-NCIDINECLSISAPCPIGHTCINTEGSYTC 334
>Z99756-1|CAI18854.1| 988|Homo sapiens protein ( Human DNA sequence
from clone RP1-100N22 on chromosome 22q13.31-13.33. ).
Length = 988
Score = 135 bits (326), Expect = 1e-31
Identities = 74/188 (39%), Positives = 96/188 (51%), Gaps = 10/188 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
+T RC C G+ +P G+ + +EC V CD C NT GS++C CR GY+L D
Sbjct: 258 DTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTD 317
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CVDINECH-EEGVCPSP 359
C+D+DEC + TC IC N+ GS++C C GY G C D++EC G C
Sbjct: 318 ERTCQDIDECSFE-RTCDHICINSPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQG 376
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC---AQTG-RCQAPCRNYAGGYRC--DC 521
CVN GS+ CVCP G RL G CV+ +C A+T R Q C G C C
Sbjct: 377 --CVNTKGSYECVCPPGRRLHWNGKDCVETGKCLSRAKTSPRAQLSCSKAGGVESCFLSC 434
Query: 522 PVGTVRSP 545
P T+ P
Sbjct: 435 PAHTLFVP 442
Score = 130 bits (315), Expect = 2e-30
Identities = 66/169 (39%), Positives = 82/169 (48%), Gaps = 3/169 (1%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDE 212
C C Y G + CAV CD+ C +T C C G+ L DG C+D++E
Sbjct: 226 CGCHQKYALHSDGRTCIETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINE 285
Query: 213 CERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLLGS 386
C + C C NT GS+EC C GY+ D C DI+EC E C C+N GS
Sbjct: 286 CLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDH--ICINSPGS 343
Query: 387 FRCVCPRGYRLDAEGARCVDRDECAQT-GRCQAPCRNYAGGYRCDCPVG 530
F+C+C RGY L C D DEC+ + G C C N G Y C CP G
Sbjct: 344 FQCLCHRGYILYGT-THCGDVDECSMSNGSCDQGCVNTKGSYECVCPPG 391
Score = 107 bits (258), Expect = 2e-23
Identities = 64/177 (36%), Positives = 83/177 (46%), Gaps = 16/177 (9%)
Frame = +3
Query: 48 GYRPAGRGVRGR---DECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDE 212
G G G+ G DEC+ C D +C NT SY CLC+ GY+ +G C D+DE
Sbjct: 20 GRLAGGSGLPGSVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYK--GEGKQCEDIDE 77
Query: 213 CERDTHT--CQQICSNTEGSYECSCEDGY--EKRGDACVDINECHE-EGVCPSPGRCVNL 377
CE D + C C N G+Y C+C DG+ G C+D++EC + G C CVN
Sbjct: 78 CENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ--ICVNA 135
Query: 378 LGSFRCVCPRGYRLDAEGARCVDRD----ECAQTGR-CQAPCRNY-AGGYRCDCPVG 530
+GS+ C C G+ L C+ R C C CR GG CDC G
Sbjct: 136 MGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPG 192
Score = 104 bits (249), Expect = 2e-22
Identities = 60/178 (33%), Positives = 78/178 (43%), Gaps = 8/178 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECA--VRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT S++C+C PGY+ G+ DEC C C N G+Y C C G+ L D
Sbjct: 52 NTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCVHECINIPGNYRCTCFDGFMLAHD 111
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGR 365
G NC DVDEC+ + CQQIC N GSYEC C G+ + I+ +E C +
Sbjct: 112 GHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDH 171
Query: 366 -CVNLL-----GSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
C ++ G C C G+ L C G CQ C + G C C
Sbjct: 172 GCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYG-NGGCQHSCEDTDTGPTCGC 228
Score = 101 bits (242), Expect = 2e-21
Identities = 57/175 (32%), Positives = 74/175 (42%), Gaps = 3/175 (1%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 200
G C C PG+ A C C C +TD C C Y L DG C
Sbjct: 183 GGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTC- 241
Query: 201 DVDECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINECH-EEGVCPSPGRCV 371
++ C + C + C +T CSC G+ + G C DINEC G C C
Sbjct: 242 -IETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDH--FCR 298
Query: 372 NLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTV 536
N +GSF C C +GY+L + C D DEC+ C C N G ++C C G +
Sbjct: 299 NTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDHICINSPGSFQCLCHRGYI 353
Score = 98.7 bits (235), Expect = 1e-20
Identities = 59/192 (30%), Positives = 84/192 (43%), Gaps = 11/192 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+N G++RC C G+ A G DEC C Q+C N GSY+C C +G+ L +
Sbjct: 92 INIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSD 151
Query: 183 DGANC----RDVDECERDTHTCQQICSNT-EGSYECSCEDGYE---KRGDACVDINECHE 338
+ C + C H C IC T +G C C G++ + D + N +
Sbjct: 152 NQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCN--YG 209
Query: 339 EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRC 515
G C C + C C + Y L ++G C++ CA G C C++ A G RC
Sbjct: 210 NGGCQHS--CEDTDTGPTCGCHQKYALHSDGRTCIET--CAVNNGGCDRTCKDTATGVRC 265
Query: 516 DCPVGTVRSPSG 551
CPVG P G
Sbjct: 266 SCPVGFTLQPDG 277
Score = 64.9 bits (151), Expect = 2e-10
Identities = 34/93 (36%), Positives = 48/93 (51%), Gaps = 4/93 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGR-DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
+N+ GSF+C+C GY G G DEC++ CDQ C NT GSY+C+C G L +
Sbjct: 338 INSPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQGCVNTKGSYECVCPPGRRLHWN 397
Query: 186 GANCRDVDEC---ERDTHTCQQICSNTEGSYEC 275
G +C + +C + + Q CS G C
Sbjct: 398 GKDCVETGKCLSRAKTSPRAQLSCSKAGGVESC 430
Score = 56.4 bits (130), Expect = 6e-08
Identities = 31/83 (37%), Positives = 40/83 (48%), Gaps = 4/83 (4%)
Frame = +3
Query: 315 VDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ---TGRCQA 482
VD++EC E C C N S++C+C GY+ EG +C D DEC G C
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYK--GEGKQCEDIDECENDYYNGGCVH 89
Query: 483 PCRNYAGGYRCDCPVGTVRSPSG 551
C N G YRC C G + + G
Sbjct: 90 ECINIPGNYRCTCFDGFMLAHDG 112
>Z82214-3|CAI21674.1| 988|Homo sapiens protein ( Human DNA sequence
from clone RP3-526I14 on chromosome 22. ).
Length = 988
Score = 135 bits (326), Expect = 1e-31
Identities = 74/188 (39%), Positives = 96/188 (51%), Gaps = 10/188 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
+T RC C G+ +P G+ + +EC V CD C NT GS++C CR GY+L D
Sbjct: 258 DTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTD 317
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CVDINECH-EEGVCPSP 359
C+D+DEC + TC IC N+ GS++C C GY G C D++EC G C
Sbjct: 318 ERTCQDIDECSFE-RTCDHICINSPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQG 376
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC---AQTG-RCQAPCRNYAGGYRC--DC 521
CVN GS+ CVCP G RL G CV+ +C A+T R Q C G C C
Sbjct: 377 --CVNTKGSYECVCPPGRRLHWNGKDCVETGKCLSRAKTSPRAQLSCSKAGGVESCFLSC 434
Query: 522 PVGTVRSP 545
P T+ P
Sbjct: 435 PAHTLFVP 442
Score = 130 bits (315), Expect = 2e-30
Identities = 66/169 (39%), Positives = 82/169 (48%), Gaps = 3/169 (1%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDE 212
C C Y G + CAV CD+ C +T C C G+ L DG C+D++E
Sbjct: 226 CGCHQKYALHSDGRTCIETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINE 285
Query: 213 CERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLLGS 386
C + C C NT GS+EC C GY+ D C DI+EC E C C+N GS
Sbjct: 286 CLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDH--ICINSPGS 343
Query: 387 FRCVCPRGYRLDAEGARCVDRDECAQT-GRCQAPCRNYAGGYRCDCPVG 530
F+C+C RGY L C D DEC+ + G C C N G Y C CP G
Sbjct: 344 FQCLCHRGYILYGT-THCGDVDECSMSNGSCDQGCVNTKGSYECVCPPG 391
Score = 107 bits (258), Expect = 2e-23
Identities = 64/177 (36%), Positives = 83/177 (46%), Gaps = 16/177 (9%)
Frame = +3
Query: 48 GYRPAGRGVRGR---DECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDE 212
G G G+ G DEC+ C D +C NT SY CLC+ GY+ +G C D+DE
Sbjct: 20 GRLAGGSGLPGSVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYK--GEGKQCEDIDE 77
Query: 213 CERDTHT--CQQICSNTEGSYECSCEDGY--EKRGDACVDINECHE-EGVCPSPGRCVNL 377
CE D + C C N G+Y C+C DG+ G C+D++EC + G C CVN
Sbjct: 78 CENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ--ICVNA 135
Query: 378 LGSFRCVCPRGYRLDAEGARCVDRD----ECAQTGR-CQAPCRNY-AGGYRCDCPVG 530
+GS+ C C G+ L C+ R C C CR GG CDC G
Sbjct: 136 MGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPG 192
Score = 104 bits (249), Expect = 2e-22
Identities = 60/178 (33%), Positives = 78/178 (43%), Gaps = 8/178 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECA--VRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT S++C+C PGY+ G+ DEC C C N G+Y C C G+ L D
Sbjct: 52 NTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCVHECINIPGNYRCTCFDGFMLAHD 111
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGR 365
G NC DVDEC+ + CQQIC N GSYEC C G+ + I+ +E C +
Sbjct: 112 GHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDH 171
Query: 366 -CVNLL-----GSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
C ++ G C C G+ L C G CQ C + G C C
Sbjct: 172 GCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYG-NGGCQHSCEDTDTGPTCGC 228
Score = 101 bits (242), Expect = 2e-21
Identities = 57/175 (32%), Positives = 74/175 (42%), Gaps = 3/175 (1%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 200
G C C PG+ A C C C +TD C C Y L DG C
Sbjct: 183 GGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTC- 241
Query: 201 DVDECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINECH-EEGVCPSPGRCV 371
++ C + C + C +T CSC G+ + G C DINEC G C C
Sbjct: 242 -IETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDH--FCR 298
Query: 372 NLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTV 536
N +GSF C C +GY+L + C D DEC+ C C N G ++C C G +
Sbjct: 299 NTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDHICINSPGSFQCLCHRGYI 353
Score = 98.7 bits (235), Expect = 1e-20
Identities = 59/192 (30%), Positives = 84/192 (43%), Gaps = 11/192 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+N G++RC C G+ A G DEC C Q+C N GSY+C C +G+ L +
Sbjct: 92 INIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSD 151
Query: 183 DGANC----RDVDECERDTHTCQQICSNT-EGSYECSCEDGYE---KRGDACVDINECHE 338
+ C + C H C IC T +G C C G++ + D + N +
Sbjct: 152 NQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCN--YG 209
Query: 339 EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRC 515
G C C + C C + Y L ++G C++ CA G C C++ A G RC
Sbjct: 210 NGGCQHS--CEDTDTGPTCGCHQKYALHSDGRTCIET--CAVNNGGCDRTCKDTATGVRC 265
Query: 516 DCPVGTVRSPSG 551
CPVG P G
Sbjct: 266 SCPVGFTLQPDG 277
Score = 64.9 bits (151), Expect = 2e-10
Identities = 34/93 (36%), Positives = 48/93 (51%), Gaps = 4/93 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGR-DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
+N+ GSF+C+C GY G G DEC++ CDQ C NT GSY+C+C G L +
Sbjct: 338 INSPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQGCVNTKGSYECVCPPGRRLHWN 397
Query: 186 GANCRDVDEC---ERDTHTCQQICSNTEGSYEC 275
G +C + +C + + Q CS G C
Sbjct: 398 GKDCVETGKCLSRAKTSPRAQLSCSKAGGVESC 430
Score = 56.4 bits (130), Expect = 6e-08
Identities = 31/83 (37%), Positives = 40/83 (48%), Gaps = 4/83 (4%)
Frame = +3
Query: 315 VDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ---TGRCQA 482
VD++EC E C C N S++C+C GY+ EG +C D DEC G C
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYK--GEGKQCEDIDECENDYYNGGCVH 89
Query: 483 PCRNYAGGYRCDCPVGTVRSPSG 551
C N G YRC C G + + G
Sbjct: 90 ECINIPGNYRCTCFDGFMLAHDG 112
>Z98047-1|CAI19628.1| 703|Homo sapiens fibulin 1 protein.
Length = 703
Score = 134 bits (325), Expect = 1e-31
Identities = 83/195 (42%), Positives = 99/195 (50%), Gaps = 15/195 (7%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPP-CDQLCHNTDGSYDCLCRTGYE 173
R VN+ GSFRC C GY G R +EC P C C NT GSY C C G+
Sbjct: 372 RCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFR 431
Query: 174 LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR---GDACVDINECH-EE 341
L DG +C D++EC + C Q C+N GSY+C C GY+ G C DI+EC
Sbjct: 432 LSVDGRSCEDINEC--SSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPT 489
Query: 342 GVCPSPGRCVNLLGSFRCVCP-RGYRLDAEGARCVDRDECAQTG--RC--QAPCRNYAGG 506
G RC+N+ GSF+C CP GYRL G C D DEC TG C C N GG
Sbjct: 490 GGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECV-TGIHNCSINETCFNIQGG 548
Query: 507 YRC---DCPVGTVRS 542
+RC +CP RS
Sbjct: 549 FRCLAFECPENYRRS 563
Score = 124 bits (300), Expect = 2e-28
Identities = 81/204 (39%), Positives = 98/204 (48%), Gaps = 23/204 (11%)
Frame = +3
Query: 9 VNTIGSFRCV----CGPGYR-PAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCL---- 155
+NT+GSFRC CG GY + DEC C D +C NT GS+ C
Sbjct: 234 INTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 293
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-----SCEDGYE--KRGD 308
C++G+ D G NC D++EC + C C NTEGSY C +C GY + G
Sbjct: 294 CKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 309 ACVDINECHEEGV-CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGR-CQ 479
CVD++EC C RCVN GSFRC C GY D CVD +EC + GR C
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG 412
Query: 480 APCRNYAGGYRCDCPVGTVRSPSG 551
C N G Y C C VG S G
Sbjct: 413 HKCENTLGSYLCSCSVGFRLSVDG 436
Score = 120 bits (288), Expect = 4e-27
Identities = 71/173 (41%), Positives = 86/173 (49%), Gaps = 13/173 (7%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL-DE 182
NT+GS+ C C G+R + GR +EC+ PC Q C N GSY C CR GY+L D
Sbjct: 417 NTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCSQECANVYGSYQCYCRRGYQLSDV 474
Query: 183 DGANCRDVDECERDT--HTCQQICSNTEGSYECSC-EDGYE--KRGDACVDINECHEEGV 347
DG C D+DEC T H C C N GS++CSC GY G C DI+EC G+
Sbjct: 475 DGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDEC-VTGI 533
Query: 348 --CPSPGRCVNLLGSFRCV---CPRGYRLDAEGARCVDRDECAQTGRCQAPCR 491
C C N+ G FRC+ CP YR A + E T RC CR
Sbjct: 534 HNCSINETCFNIQGGFRCLAFECPENYRRSA----ATLQQEKTDTVRCIKSCR 582
Score = 102 bits (244), Expect = 1e-21
Identities = 62/152 (40%), Positives = 78/152 (51%), Gaps = 16/152 (10%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-- 275
PC Q C +T C C GY+L DG +C DV+EC +H+C+ + C NT GS+ C
Sbjct: 185 PCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 244
Query: 276 --SCEDGYEKRGD-ACVDINECHEEGV--CPSPGRCVNLLGSFRC----VCPRGYRLDAE 428
SC GYE D +C DI+EC E G+ C C N LGSFRC C G+ DA
Sbjct: 245 DSSCGTGYELTEDNSCKDIDEC-ESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL 303
Query: 429 GARCVDRDECAQ-TGRCQA--PCRNYAGGYRC 515
G C+D +EC + C C N G Y C
Sbjct: 304 G-NCIDINECLSISAPCPIGHTCINTEGSYTC 334
>Z95331-3|CAI41717.1| 703|Homo sapiens fibulin 1 protein.
Length = 703
Score = 134 bits (325), Expect = 1e-31
Identities = 83/195 (42%), Positives = 99/195 (50%), Gaps = 15/195 (7%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPP-CDQLCHNTDGSYDCLCRTGYE 173
R VN+ GSFRC C GY G R +EC P C C NT GSY C C G+
Sbjct: 372 RCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFR 431
Query: 174 LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR---GDACVDINECH-EE 341
L DG +C D++EC + C Q C+N GSY+C C GY+ G C DI+EC
Sbjct: 432 LSVDGRSCEDINEC--SSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPT 489
Query: 342 GVCPSPGRCVNLLGSFRCVCP-RGYRLDAEGARCVDRDECAQTG--RC--QAPCRNYAGG 506
G RC+N+ GSF+C CP GYRL G C D DEC TG C C N GG
Sbjct: 490 GGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECV-TGIHNCSINETCFNIQGG 548
Query: 507 YRC---DCPVGTVRS 542
+RC +CP RS
Sbjct: 549 FRCLAFECPENYRRS 563
Score = 124 bits (300), Expect = 2e-28
Identities = 81/204 (39%), Positives = 98/204 (48%), Gaps = 23/204 (11%)
Frame = +3
Query: 9 VNTIGSFRCV----CGPGYR-PAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCL---- 155
+NT+GSFRC CG GY + DEC C D +C NT GS+ C
Sbjct: 234 INTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 293
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-----SCEDGYE--KRGD 308
C++G+ D G NC D++EC + C C NTEGSY C +C GY + G
Sbjct: 294 CKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 309 ACVDINECHEEGV-CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGR-CQ 479
CVD++EC C RCVN GSFRC C GY D CVD +EC + GR C
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG 412
Query: 480 APCRNYAGGYRCDCPVGTVRSPSG 551
C N G Y C C VG S G
Sbjct: 413 HKCENTLGSYLCSCSVGFRLSVDG 436
Score = 120 bits (288), Expect = 4e-27
Identities = 71/173 (41%), Positives = 86/173 (49%), Gaps = 13/173 (7%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL-DE 182
NT+GS+ C C G+R + GR +EC+ PC Q C N GSY C CR GY+L D
Sbjct: 417 NTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCSQECANVYGSYQCYCRRGYQLSDV 474
Query: 183 DGANCRDVDECERDT--HTCQQICSNTEGSYECSC-EDGYE--KRGDACVDINECHEEGV 347
DG C D+DEC T H C C N GS++CSC GY G C DI+EC G+
Sbjct: 475 DGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDEC-VTGI 533
Query: 348 --CPSPGRCVNLLGSFRCV---CPRGYRLDAEGARCVDRDECAQTGRCQAPCR 491
C C N+ G FRC+ CP YR A + E T RC CR
Sbjct: 534 HNCSINETCFNIQGGFRCLAFECPENYRRSA----ATLQQEKTDTVRCIKSCR 582
Score = 102 bits (244), Expect = 1e-21
Identities = 62/152 (40%), Positives = 78/152 (51%), Gaps = 16/152 (10%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-- 275
PC Q C +T C C GY+L DG +C DV+EC +H+C+ + C NT GS+ C
Sbjct: 185 PCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 244
Query: 276 --SCEDGYEKRGD-ACVDINECHEEGV--CPSPGRCVNLLGSFRC----VCPRGYRLDAE 428
SC GYE D +C DI+EC E G+ C C N LGSFRC C G+ DA
Sbjct: 245 DSSCGTGYELTEDNSCKDIDEC-ESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL 303
Query: 429 GARCVDRDECAQ-TGRCQA--PCRNYAGGYRC 515
G C+D +EC + C C N G Y C
Sbjct: 304 G-NCIDINECLSISAPCPIGHTCINTEGSYTC 334
>AL021391-3|CAI18930.1| 703|Homo sapiens fibulin 1 protein.
Length = 703
Score = 134 bits (325), Expect = 1e-31
Identities = 83/195 (42%), Positives = 99/195 (50%), Gaps = 15/195 (7%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPP-CDQLCHNTDGSYDCLCRTGYE 173
R VN+ GSFRC C GY G R +EC P C C NT GSY C C G+
Sbjct: 372 RCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFR 431
Query: 174 LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR---GDACVDINECH-EE 341
L DG +C D++EC + C Q C+N GSY+C C GY+ G C DI+EC
Sbjct: 432 LSVDGRSCEDINEC--SSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPT 489
Query: 342 GVCPSPGRCVNLLGSFRCVCP-RGYRLDAEGARCVDRDECAQTG--RC--QAPCRNYAGG 506
G RC+N+ GSF+C CP GYRL G C D DEC TG C C N GG
Sbjct: 490 GGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECV-TGIHNCSINETCFNIQGG 548
Query: 507 YRC---DCPVGTVRS 542
+RC +CP RS
Sbjct: 549 FRCLAFECPENYRRS 563
Score = 124 bits (300), Expect = 2e-28
Identities = 81/204 (39%), Positives = 98/204 (48%), Gaps = 23/204 (11%)
Frame = +3
Query: 9 VNTIGSFRCV----CGPGYR-PAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCL---- 155
+NT+GSFRC CG GY + DEC C D +C NT GS+ C
Sbjct: 234 INTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 293
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-----SCEDGYE--KRGD 308
C++G+ D G NC D++EC + C C NTEGSY C +C GY + G
Sbjct: 294 CKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 309 ACVDINECHEEGV-CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGR-CQ 479
CVD++EC C RCVN GSFRC C GY D CVD +EC + GR C
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG 412
Query: 480 APCRNYAGGYRCDCPVGTVRSPSG 551
C N G Y C C VG S G
Sbjct: 413 HKCENTLGSYLCSCSVGFRLSVDG 436
Score = 120 bits (288), Expect = 4e-27
Identities = 71/173 (41%), Positives = 86/173 (49%), Gaps = 13/173 (7%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL-DE 182
NT+GS+ C C G+R + GR +EC+ PC Q C N GSY C CR GY+L D
Sbjct: 417 NTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCSQECANVYGSYQCYCRRGYQLSDV 474
Query: 183 DGANCRDVDECERDT--HTCQQICSNTEGSYECSC-EDGYE--KRGDACVDINECHEEGV 347
DG C D+DEC T H C C N GS++CSC GY G C DI+EC G+
Sbjct: 475 DGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDEC-VTGI 533
Query: 348 --CPSPGRCVNLLGSFRCV---CPRGYRLDAEGARCVDRDECAQTGRCQAPCR 491
C C N+ G FRC+ CP YR A + E T RC CR
Sbjct: 534 HNCSINETCFNIQGGFRCLAFECPENYRRSA----ATLQQEKTDTVRCIKSCR 582
Score = 102 bits (244), Expect = 1e-21
Identities = 62/152 (40%), Positives = 78/152 (51%), Gaps = 16/152 (10%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-- 275
PC Q C +T C C GY+L DG +C DV+EC +H+C+ + C NT GS+ C
Sbjct: 185 PCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 244
Query: 276 --SCEDGYEKRGD-ACVDINECHEEGV--CPSPGRCVNLLGSFRC----VCPRGYRLDAE 428
SC GYE D +C DI+EC E G+ C C N LGSFRC C G+ DA
Sbjct: 245 DSSCGTGYELTEDNSCKDIDEC-ESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL 303
Query: 429 GARCVDRDECAQ-TGRCQA--PCRNYAGGYRC 515
G C+D +EC + C C N G Y C
Sbjct: 304 G-NCIDINECLSISAPCPIGHTCINTEGSYTC 334
>AK075566-1|BAC11705.1| 638|Homo sapiens protein ( Homo sapiens
cDNA PSEC0266 fis, clone NT2RP3003649, highly similar to
Homo sapiens fibulin-1D mRNA. ).
Length = 638
Score = 134 bits (325), Expect = 1e-31
Identities = 83/195 (42%), Positives = 99/195 (50%), Gaps = 15/195 (7%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPP-CDQLCHNTDGSYDCLCRTGYE 173
R VN+ GSFRC C GY G R +EC P C C NT GSY C C G+
Sbjct: 307 RCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFR 366
Query: 174 LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR---GDACVDINECH-EE 341
L DG +C D++EC + C Q C+N GSY+C C GY+ G C DI+EC
Sbjct: 367 LSVDGRSCEDINEC--SSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPT 424
Query: 342 GVCPSPGRCVNLLGSFRCVCP-RGYRLDAEGARCVDRDECAQTG--RC--QAPCRNYAGG 506
G RC+N+ GSF+C CP GYRL G C D DEC TG C C N GG
Sbjct: 425 GGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECV-TGIHNCSINETCFNIQGG 483
Query: 507 YRC---DCPVGTVRS 542
+RC +CP RS
Sbjct: 484 FRCLAFECPENYRRS 498
Score = 124 bits (300), Expect = 2e-28
Identities = 81/204 (39%), Positives = 98/204 (48%), Gaps = 23/204 (11%)
Frame = +3
Query: 9 VNTIGSFRCV----CGPGYR-PAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCL---- 155
+NT+GSFRC CG GY + DEC C D +C NT GS+ C
Sbjct: 169 INTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 228
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-----SCEDGYE--KRGD 308
C++G+ D G NC D++EC + C C NTEGSY C +C GY + G
Sbjct: 229 CKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 287
Query: 309 ACVDINECHEEGV-CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGR-CQ 479
CVD++EC C RCVN GSFRC C GY D CVD +EC + GR C
Sbjct: 288 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG 347
Query: 480 APCRNYAGGYRCDCPVGTVRSPSG 551
C N G Y C C VG S G
Sbjct: 348 HKCENTLGSYLCSCSVGFRLSVDG 371
Score = 120 bits (288), Expect = 4e-27
Identities = 71/173 (41%), Positives = 86/173 (49%), Gaps = 13/173 (7%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL-DE 182
NT+GS+ C C G+R + GR +EC+ PC Q C N GSY C CR GY+L D
Sbjct: 352 NTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCSQECANVYGSYQCYCRRGYQLSDV 409
Query: 183 DGANCRDVDECERDT--HTCQQICSNTEGSYECSC-EDGYE--KRGDACVDINECHEEGV 347
DG C D+DEC T H C C N GS++CSC GY G C DI+EC G+
Sbjct: 410 DGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDEC-VTGI 468
Query: 348 --CPSPGRCVNLLGSFRCV---CPRGYRLDAEGARCVDRDECAQTGRCQAPCR 491
C C N+ G FRC+ CP YR A + E T RC CR
Sbjct: 469 HNCSINETCFNIQGGFRCLAFECPENYRRSA----ATLQQEKTDTVRCIKSCR 517
Score = 102 bits (244), Expect = 1e-21
Identities = 62/152 (40%), Positives = 78/152 (51%), Gaps = 16/152 (10%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-- 275
PC Q C +T C C GY+L DG +C DV+EC +H+C+ + C NT GS+ C
Sbjct: 120 PCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 179
Query: 276 --SCEDGYEKRGD-ACVDINECHEEGV--CPSPGRCVNLLGSFRC----VCPRGYRLDAE 428
SC GYE D +C DI+EC E G+ C C N LGSFRC C G+ DA
Sbjct: 180 DSSCGTGYELTEDNSCKDIDEC-ESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL 238
Query: 429 GARCVDRDECAQ-TGRCQA--PCRNYAGGYRC 515
G C+D +EC + C C N G Y C
Sbjct: 239 G-NCIDINECLSISAPCPIGHTCINTEGSYTC 269
>AF525689-1|AAN77133.1| 988|Homo sapiens signal
peptide-CUB-EGF-like domain containing protein 1
protein.
Length = 988
Score = 134 bits (325), Expect = 1e-31
Identities = 67/169 (39%), Positives = 83/169 (49%), Gaps = 3/169 (1%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDE 212
C C Y P G + CAV CD+ C +T C C G+ L DG C+D++E
Sbjct: 226 CGCHQKYAPHSDGRTCIETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINE 285
Query: 213 CERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLLGS 386
C + C C NT GS+EC C GY+ D C DI+EC E C C+N GS
Sbjct: 286 CLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDH--ICINSPGS 343
Query: 387 FRCVCPRGYRLDAEGARCVDRDECAQT-GRCQAPCRNYAGGYRCDCPVG 530
F+C+C RGY L C D DEC+ + G C C N G Y C CP G
Sbjct: 344 FQCLCHRGYILYGT-THCGDVDECSMSNGSCDQGCVNTKGSYECVCPPG 391
Score = 132 bits (318), Expect = 1e-30
Identities = 73/188 (38%), Positives = 95/188 (50%), Gaps = 10/188 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
+T RC C G+ +P G+ + +EC V CD C NT GS++C CR GY+L D
Sbjct: 258 DTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTD 317
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CVDINECH-EEGVCPSP 359
C+D+DEC + TC IC N+ GS++C C GY G C D++EC G C
Sbjct: 318 ERTCQDIDECSFE-RTCDHICINSPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQG 376
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC---AQTG-RCQAPCRNYAGGYRC--DC 521
CVN GS+ CVCP G RL CV+ +C A+T R Q C G C C
Sbjct: 377 --CVNTKGSYECVCPPGRRLHWNRKDCVETGKCLSRAKTSPRAQLSCSKAGGVESCFLSC 434
Query: 522 PVGTVRSP 545
P T+ P
Sbjct: 435 PAHTLFVP 442
Score = 105 bits (251), Expect = 1e-22
Identities = 63/177 (35%), Positives = 82/177 (46%), Gaps = 16/177 (9%)
Frame = +3
Query: 48 GYRPAGRGVRGR---DECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDE 212
G G G+ G DEC+ C D +C N SY CLC+ GY+ +G C D+DE
Sbjct: 20 GRLAGGSGLPGSVDVDECSEGTDDCHIDAICQNAPKSYKCLCKPGYK--GEGKQCGDIDE 77
Query: 213 CERDTHT--CQQICSNTEGSYECSCEDGY--EKRGDACVDINECHE-EGVCPSPGRCVNL 377
CE D + C C N G+Y C+C DG+ G C+D++EC + G C CVN
Sbjct: 78 CENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ--ICVNA 135
Query: 378 LGSFRCVCPRGYRLDAEGARCVDRD----ECAQTGR-CQAPCRNY-AGGYRCDCPVG 530
+GS+ C C G+ L C+ R C C CR GG CDC G
Sbjct: 136 MGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPG 192
Score = 101 bits (242), Expect = 2e-21
Identities = 59/178 (33%), Positives = 77/178 (43%), Gaps = 8/178 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECA--VRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
N S++C+C PGY+ G+ DEC C C N G+Y C C G+ L D
Sbjct: 52 NAPKSYKCLCKPGYKGEGKQCGDIDECENDYYNGGCVHECINIPGNYRCTCFDGFMLAHD 111
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGR 365
G NC DVDEC+ + CQQIC N GSYEC C G+ + I+ +E C +
Sbjct: 112 GHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDH 171
Query: 366 -CVNLL-----GSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
C ++ G C C G+ L C G CQ C + G C C
Sbjct: 172 GCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYG-NGGCQHSCEDTDTGPTCGC 228
Score = 98.7 bits (235), Expect = 1e-20
Identities = 56/175 (32%), Positives = 73/175 (41%), Gaps = 3/175 (1%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 200
G C C PG+ A C C C +TD C C Y DG C
Sbjct: 183 GGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKYAPHSDGRTC- 241
Query: 201 DVDECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINECH-EEGVCPSPGRCV 371
++ C + C + C +T CSC G+ + G C DINEC G C C
Sbjct: 242 -IETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDH--FCR 298
Query: 372 NLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTV 536
N +GSF C C +GY+L + C D DEC+ C C N G ++C C G +
Sbjct: 299 NTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDHICINSPGSFQCLCHRGYI 353
Score = 95.9 bits (228), Expect = 8e-20
Identities = 58/192 (30%), Positives = 83/192 (43%), Gaps = 11/192 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+N G++RC C G+ A G DEC C Q+C N GSY+C C +G+ L +
Sbjct: 92 INIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSD 151
Query: 183 DGANC----RDVDECERDTHTCQQICSNT-EGSYECSCEDGYE---KRGDACVDINECHE 338
+ C + C H C IC T +G C C G++ + D + N +
Sbjct: 152 NQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCN--YG 209
Query: 339 EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRC 515
G C C + C C + Y ++G C++ CA G C C++ A G RC
Sbjct: 210 NGGCQHS--CEDTDTGPTCGCHQKYAPHSDGRTCIET--CAVNNGGCDRTCKDTATGVRC 265
Query: 516 DCPVGTVRSPSG 551
CPVG P G
Sbjct: 266 SCPVGFTLQPDG 277
Score = 61.7 bits (143), Expect = 2e-09
Identities = 33/93 (35%), Positives = 47/93 (50%), Gaps = 4/93 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGR-DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
+N+ GSF+C+C GY G G DEC++ CDQ C NT GSY+C+C G L +
Sbjct: 338 INSPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQGCVNTKGSYECVCPPGRRLHWN 397
Query: 186 GANCRDVDEC---ERDTHTCQQICSNTEGSYEC 275
+C + +C + + Q CS G C
Sbjct: 398 RKDCVETGKCLSRAKTSPRAQLSCSKAGGVESC 430
Score = 56.0 bits (129), Expect = 8e-08
Identities = 31/83 (37%), Positives = 40/83 (48%), Gaps = 4/83 (4%)
Frame = +3
Query: 315 VDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ---TGRCQA 482
VD++EC E C C N S++C+C GY+ EG +C D DEC G C
Sbjct: 32 VDVDECSEGTDDCHIDAICQNAPKSYKCLCKPGYK--GEGKQCGDIDECENDYYNGGCVH 89
Query: 483 PCRNYAGGYRCDCPVGTVRSPSG 551
C N G YRC C G + + G
Sbjct: 90 ECINIPGNYRCTCFDGFMLAHDG 112
>AF217999-1|AAG17241.1| 495|Homo sapiens unknown protein.
Length = 495
Score = 134 bits (325), Expect = 1e-31
Identities = 83/195 (42%), Positives = 99/195 (50%), Gaps = 15/195 (7%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPP-CDQLCHNTDGSYDCLCRTGYE 173
R VN+ GSFRC C GY G R +EC P C C NT GSY C C G+
Sbjct: 242 RCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFR 301
Query: 174 LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR---GDACVDINECH-EE 341
L DG +C D++EC + C Q C+N GSY+C C GY+ G C DI+EC
Sbjct: 302 LSVDGRSCEDINEC--SSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPT 359
Query: 342 GVCPSPGRCVNLLGSFRCVCP-RGYRLDAEGARCVDRDECAQTG--RC--QAPCRNYAGG 506
G RC+N+ GSF+C CP GYRL G C D DEC TG C C N GG
Sbjct: 360 GGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECV-TGIHNCSINETCFNIQGG 418
Query: 507 YRC---DCPVGTVRS 542
+RC +CP RS
Sbjct: 419 FRCLAFECPENYRRS 433
Score = 124 bits (300), Expect = 2e-28
Identities = 81/204 (39%), Positives = 98/204 (48%), Gaps = 23/204 (11%)
Frame = +3
Query: 9 VNTIGSFRCV----CGPGYR-PAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCL---- 155
+NT+GSFRC CG GY + DEC C D +C NT GS+ C
Sbjct: 104 INTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 163
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-----SCEDGYE--KRGD 308
C++G+ D G NC D++EC + C C NTEGSY C +C GY + G
Sbjct: 164 CKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 222
Query: 309 ACVDINECHEEGV-CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGR-CQ 479
CVD++EC C RCVN GSFRC C GY D CVD +EC + GR C
Sbjct: 223 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG 282
Query: 480 APCRNYAGGYRCDCPVGTVRSPSG 551
C N G Y C C VG S G
Sbjct: 283 HKCENTLGSYLCSCSVGFRLSVDG 306
Score = 121 bits (291), Expect = 2e-27
Identities = 70/168 (41%), Positives = 86/168 (51%), Gaps = 13/168 (7%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL-DE 182
NT+GS+ C C G+R + GR +EC+ PC Q C N GSY C CR GY+L D
Sbjct: 287 NTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCSQECANVYGSYQCYCRRGYQLSDV 344
Query: 183 DGANCRDVDECERDT--HTCQQICSNTEGSYECSC-EDGYE--KRGDACVDINECHEEGV 347
DG C D+DEC T H C C N GS++CSC GY G C DI+EC G+
Sbjct: 345 DGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDEC-VTGI 403
Query: 348 --CPSPGRCVNLLGSFRCV---CPRGYRLDAEGARCVDRDECAQTGRC 476
C C N+ G FRC+ CP YR A RC +R C + C
Sbjct: 404 HNCSINETCFNIQGGFRCLAFECPENYRRSA-ATRC-ERLPCHENREC 449
Score = 102 bits (244), Expect = 1e-21
Identities = 62/152 (40%), Positives = 78/152 (51%), Gaps = 16/152 (10%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-- 275
PC Q C +T C C GY+L DG +C DV+EC +H+C+ + C NT GS+ C
Sbjct: 55 PCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 114
Query: 276 --SCEDGYEKRGD-ACVDINECHEEGV--CPSPGRCVNLLGSFRC----VCPRGYRLDAE 428
SC GYE D +C DI+EC E G+ C C N LGSFRC C G+ DA
Sbjct: 115 DSSCGTGYELTEDNSCKDIDEC-ESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL 173
Query: 429 GARCVDRDECAQ-TGRCQA--PCRNYAGGYRC 515
G C+D +EC + C C N G Y C
Sbjct: 174 G-NCIDINECLSISAPCPIGHTCINTEGSYTC 204
>AY358898-1|AAQ89257.1| 448|Homo sapiens FBLN5 protein.
Length = 448
Score = 134 bits (324), Expect = 2e-31
Identities = 67/156 (42%), Positives = 82/156 (52%), Gaps = 5/156 (3%)
Frame = +3
Query: 84 DECAVRPPPCD--QLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNT 257
DECA C+ Q+C NT+G Y C C GY L E C D+DEC CQQ+C+N
Sbjct: 129 DECATDSHQCNPTQICINTEGGYTCSCTDGYWLLE--GQCLDIDECRYG--YCQQLCANV 184
Query: 258 EGSYECSCEDGY--EKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEG 431
GSY C+C G+ + G +C D+NEC E C CVN GS C C GY L+ +G
Sbjct: 185 PGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQ--TCVNTYGSLICRCDPGYELEEDG 242
Query: 432 ARCVDRDECA-QTGRCQAPCRNYAGGYRCDCPVGTV 536
C D DEC+ CQ C N G Y C CP G +
Sbjct: 243 VHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYI 278
Score = 133 bits (322), Expect = 3e-31
Identities = 72/179 (40%), Positives = 92/179 (51%), Gaps = 6/179 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+NT G + C C GY DEC R C QLC N GSY C C G+ L+EDG
Sbjct: 145 INTEGGYTCSCTDGYWLLEGQCLDIDEC--RYGYCQQLCANVPGSYSCTCNPGFTLNEDG 202
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINEC-HEEGVCPSP 359
+C+DV+EC + + C Q C NT GS C C+ GYE D C D++EC E +C
Sbjct: 203 RSCQDVNECATE-NPCVQTCVNTYGSLICRCDPGYELEEDGVHCSDMDECSFSEFLCQH- 260
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA---QTGRCQAPCRNYAGGYRCDCPV 527
CVN G++ C CP GY L + C D +EC T Q C N GG++C P+
Sbjct: 261 -ECVNQPGTYFCSCPPGYILLDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPI 318
Score = 118 bits (284), Expect = 1e-26
Identities = 57/128 (44%), Positives = 69/128 (53%), Gaps = 2/128 (1%)
Frame = +3
Query: 153 LCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRGDACVDIN 326
+CR GY++DE C DVDEC D+H C QIC NTEG Y CSC DGY C+DI+
Sbjct: 112 ICRFGYQMDESN-QCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLDID 170
Query: 327 ECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGG 506
EC G C C N+ GS+ C C G+ L+ +G C D +ECA C C N G
Sbjct: 171 ECRY-GYCQQ--LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGS 227
Query: 507 YRCDCPVG 530
C C G
Sbjct: 228 LICRCDPG 235
Score = 71.3 bits (167), Expect = 2e-12
Identities = 50/162 (30%), Positives = 69/162 (42%), Gaps = 6/162 (3%)
Frame = +3
Query: 84 DECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNT 257
DEC P C D +C N +G Y C+ RT +N + +
Sbjct: 44 DECRTIPEACRGDMMCVNQNGGYLCIPRTNPVYRGPYSNPYSTPYSGPYPAAAPPLSAPN 103
Query: 258 EG--SYECSCEDGYEK-RGDACVDINECHEEGVCPSPGR-CVNLLGSFRCVCPRGYRLDA 425
S C GY+ + CVD++EC + +P + C+N G + C C GY L
Sbjct: 104 YPTISRPLICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWL-L 162
Query: 426 EGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVRSPSG 551
EG +C+D DEC + G CQ C N G Y C C G + G
Sbjct: 163 EG-QCLDIDEC-RYGYCQQLCANVPGSYSCTCNPGFTLNEDG 202
Score = 65.7 bits (153), Expect = 1e-10
Identities = 46/146 (31%), Positives = 62/146 (42%), Gaps = 9/146 (6%)
Frame = +3
Query: 120 LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGY 293
LC + G+ C G++LD C D+DEC C+ +C N G Y C
Sbjct: 15 LCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNP 74
Query: 294 EKRGDACVDINECHEEGVCPS---PGRCVNLLGSFR-CVCPRGYRLDAEGARCVDRDECA 461
RG + + G P+ P N R +C GY++D E +CVD DECA
Sbjct: 75 VYRGPYSNPYSTPY-SGPYPAAAPPLSAPNYPTISRPLICRFGYQMD-ESNQCVDVDECA 132
Query: 462 -QTGRCQAP--CRNYAGGYRCDCPVG 530
+ +C C N GGY C C G
Sbjct: 133 TDSHQCNPTQICINTEGGYTCSCTDG 158
>AF093118-1|AAC62107.1| 448|Homo sapiens UP50 protein.
Length = 448
Score = 133 bits (321), Expect = 4e-31
Identities = 67/156 (42%), Positives = 82/156 (52%), Gaps = 5/156 (3%)
Frame = +3
Query: 84 DECAVRPPPCD--QLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNT 257
DECA C+ Q+C N G Y C C GY L E C D+DEC CQQ+C+N
Sbjct: 129 DECATDSHQCNPTQICINMKGGYTCSCTDGYWLLE--GQCLDIDECRYGY--CQQLCANV 184
Query: 258 EGSYECSCEDGY--EKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEG 431
GSY C+C G+ + G +C D+NEC E C CVN GSF C C GY L+ +G
Sbjct: 185 PGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQT--CVNTYGSFICRCDPGYELEEDG 242
Query: 432 ARCVDRDECAQTG-RCQAPCRNYAGGYRCDCPVGTV 536
C D DEC+ + CQ C N G Y C CP G +
Sbjct: 243 VHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYI 278
Score = 132 bits (320), Expect = 6e-31
Identities = 71/179 (39%), Positives = 92/179 (51%), Gaps = 6/179 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+N G + C C GY DEC R C QLC N GSY C C G+ L+EDG
Sbjct: 145 INMKGGYTCSCTDGYWLLEGQCLDIDEC--RYGYCQQLCANVPGSYSCTCNPGFTLNEDG 202
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA--CVDINEC-HEEGVCPSP 359
+C+DV+EC + + C Q C NT GS+ C C+ GYE D C D++EC E +C
Sbjct: 203 RSCQDVNECATE-NPCVQTCVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQH- 260
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA---QTGRCQAPCRNYAGGYRCDCPV 527
CVN G++ C CP GY L + C D +EC T Q C N GG++C P+
Sbjct: 261 -ECVNQPGTYFCSCPPGYILLDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPI 318
Score = 116 bits (278), Expect = 7e-26
Identities = 55/128 (42%), Positives = 69/128 (53%), Gaps = 2/128 (1%)
Frame = +3
Query: 153 LCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRGDACVDIN 326
+CR GY++DE C DVDEC D+H C QIC N +G Y CSC DGY C+DI+
Sbjct: 112 ICRFGYQMDESN-QCVDVDECATDSHQCNPTQICINMKGGYTCSCTDGYWLLEGQCLDID 170
Query: 327 ECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGG 506
EC G C C N+ GS+ C C G+ L+ +G C D +ECA C C N G
Sbjct: 171 ECRY-GYCQQ--LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGS 227
Query: 507 YRCDCPVG 530
+ C C G
Sbjct: 228 FICRCDPG 235
Score = 71.7 bits (168), Expect = 2e-12
Identities = 50/162 (30%), Positives = 69/162 (42%), Gaps = 6/162 (3%)
Frame = +3
Query: 84 DECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNT 257
DEC P C D +C N +G Y C RT +N + +
Sbjct: 44 DECRTIPEACRGDMMCVNQNGGYLCHSRTNPVYRGPYSNPYSTPYSGPYPAAAPPLSAPN 103
Query: 258 EG--SYECSCEDGYEK-RGDACVDINECHEEGVCPSPGR-CVNLLGSFRCVCPRGYRLDA 425
S C GY+ + CVD++EC + +P + C+N+ G + C C GY L
Sbjct: 104 YPTISRPLICRFGYQMDESNQCVDVDECATDSHQCNPTQICINMKGGYTCSCTDGYWL-L 162
Query: 426 EGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVRSPSG 551
EG +C+D DEC + G CQ C N G Y C C G + G
Sbjct: 163 EG-QCLDIDEC-RYGYCQQLCANVPGSYSCTCNPGFTLNEDG 202
Score = 67.3 bits (157), Expect = 3e-11
Identities = 46/146 (31%), Positives = 62/146 (42%), Gaps = 9/146 (6%)
Frame = +3
Query: 120 LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGY 293
LC + G+ C G++LD C D+DEC C+ +C N G Y C
Sbjct: 15 LCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCHSRTNP 74
Query: 294 EKRGDACVDINECHEEGVCPS---PGRCVNLLGSFR-CVCPRGYRLDAEGARCVDRDECA 461
RG + + G P+ P N R +C GY++D E +CVD DECA
Sbjct: 75 VYRGPYSNPYSTPY-SGPYPAAAPPLSAPNYPTISRPLICRFGYQMD-ESNQCVDVDECA 132
Query: 462 -QTGRCQAP--CRNYAGGYRCDCPVG 530
+ +C C N GGY C C G
Sbjct: 133 TDSHQCNPTQICINMKGGYTCSCTDG 158
>X53743-1|CAA37772.1| 683|Homo sapiens fibulin-1 C protein.
Length = 683
Score = 132 bits (319), Expect = 8e-31
Identities = 82/195 (42%), Positives = 98/195 (50%), Gaps = 15/195 (7%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPP-CDQLCHNTDGSYDCLCRTGYE 173
R VN+ GSFRC C GY G R +EC P C C NT GSY C C G+
Sbjct: 372 RCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFR 431
Query: 174 LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR---GDACVDINECH-EE 341
L DG +C D++EC + C Q C+N GSY+C C GY+ G C DI+EC
Sbjct: 432 LSVDGRSCEDINEC--SSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPT 489
Query: 342 GVCPSPGRCVNLLGSFRCVCP-RGYRLDAEGARCVDRDECAQTG--RC--QAPCRNYAGG 506
G RC+N+ GSF+C CP GYRL G C D DEC TG C C N G
Sbjct: 490 GGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECV-TGIHNCSINETCFNIQGA 548
Query: 507 YRC---DCPVGTVRS 542
+RC +CP RS
Sbjct: 549 FRCLAFECPENYRRS 563
Score = 124 bits (300), Expect = 2e-28
Identities = 81/204 (39%), Positives = 98/204 (48%), Gaps = 23/204 (11%)
Frame = +3
Query: 9 VNTIGSFRCV----CGPGYR-PAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCL---- 155
+NT+GSFRC CG GY + DEC C D +C NT GS+ C
Sbjct: 234 INTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 293
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-----SCEDGYE--KRGD 308
C++G+ D G NC D++EC + C C NTEGSY C +C GY + G
Sbjct: 294 CKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 309 ACVDINECHEEGV-CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGR-CQ 479
CVD++EC C RCVN GSFRC C GY D CVD +EC + GR C
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG 412
Query: 480 APCRNYAGGYRCDCPVGTVRSPSG 551
C N G Y C C VG S G
Sbjct: 413 HKCENTLGSYLCSCSVGFRLSVDG 436
Score = 121 bits (292), Expect = 1e-27
Identities = 70/168 (41%), Positives = 87/168 (51%), Gaps = 13/168 (7%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL-DE 182
NT+GS+ C C G+R + GR +EC+ PC Q C N GSY C CR GY+L D
Sbjct: 417 NTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCSQECANVYGSYQCYCRRGYQLSDV 474
Query: 183 DGANCRDVDECERDT--HTCQQICSNTEGSYECSC-EDGYE--KRGDACVDINECHEEGV 347
DG C D+DEC T H C C N GS++CSC GY G C DI+EC G+
Sbjct: 475 DGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDEC-VTGI 533
Query: 348 --CPSPGRCVNLLGSFRCV---CPRGYRLDAEGARCVDRDECAQTGRC 476
C C N+ G+FRC+ CP YR A RC +R C + C
Sbjct: 534 HNCSINETCFNIQGAFRCLAFECPENYRRSA-ATRC-ERLPCHENREC 579
Score = 102 bits (244), Expect = 1e-21
Identities = 62/152 (40%), Positives = 78/152 (51%), Gaps = 16/152 (10%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-- 275
PC Q C +T C C GY+L DG +C DV+EC +H+C+ + C NT GS+ C
Sbjct: 185 PCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 244
Query: 276 --SCEDGYEKRGD-ACVDINECHEEGV--CPSPGRCVNLLGSFRC----VCPRGYRLDAE 428
SC GYE D +C DI+EC E G+ C C N LGSFRC C G+ DA
Sbjct: 245 DSSCGTGYELTEDNSCKDIDEC-ESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL 303
Query: 429 GARCVDRDECAQ-TGRCQA--PCRNYAGGYRC 515
G C+D +EC + C C N G Y C
Sbjct: 304 G-NCIDINECLSISAPCPIGHTCINTEGSYTC 334
>X53742-1|CAA37771.1| 601|Homo sapiens fibulin-1 B protein.
Length = 601
Score = 132 bits (319), Expect = 8e-31
Identities = 82/195 (42%), Positives = 98/195 (50%), Gaps = 15/195 (7%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPP-CDQLCHNTDGSYDCLCRTGYE 173
R VN+ GSFRC C GY G R +EC P C C NT GSY C C G+
Sbjct: 372 RCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFR 431
Query: 174 LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR---GDACVDINECH-EE 341
L DG +C D++EC + C Q C+N GSY+C C GY+ G C DI+EC
Sbjct: 432 LSVDGRSCEDINEC--SSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPT 489
Query: 342 GVCPSPGRCVNLLGSFRCVCP-RGYRLDAEGARCVDRDECAQTG--RC--QAPCRNYAGG 506
G RC+N+ GSF+C CP GYRL G C D DEC TG C C N G
Sbjct: 490 GGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECV-TGIHNCSINETCFNIQGA 548
Query: 507 YRC---DCPVGTVRS 542
+RC +CP RS
Sbjct: 549 FRCLAFECPENYRRS 563
Score = 124 bits (300), Expect = 2e-28
Identities = 81/204 (39%), Positives = 98/204 (48%), Gaps = 23/204 (11%)
Frame = +3
Query: 9 VNTIGSFRCV----CGPGYR-PAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCL---- 155
+NT+GSFRC CG GY + DEC C D +C NT GS+ C
Sbjct: 234 INTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 293
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-----SCEDGYE--KRGD 308
C++G+ D G NC D++EC + C C NTEGSY C +C GY + G
Sbjct: 294 CKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 309 ACVDINECHEEGV-CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGR-CQ 479
CVD++EC C RCVN GSFRC C GY D CVD +EC + GR C
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG 412
Query: 480 APCRNYAGGYRCDCPVGTVRSPSG 551
C N G Y C C VG S G
Sbjct: 413 HKCENTLGSYLCSCSVGFRLSVDG 436
Score = 119 bits (287), Expect = 6e-27
Identities = 68/173 (39%), Positives = 86/173 (49%), Gaps = 13/173 (7%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL-DE 182
NT+GS+ C C G+R + GR +EC+ PC Q C N GSY C CR GY+L D
Sbjct: 417 NTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCSQECANVYGSYQCYCRRGYQLSDV 474
Query: 183 DGANCRDVDECERDT--HTCQQICSNTEGSYECSC-EDGYE--KRGDACVDINECHEEGV 347
DG C D+DEC T H C C N GS++CSC GY G C DI+EC G+
Sbjct: 475 DGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDEC-VTGI 533
Query: 348 --CPSPGRCVNLLGSFRCV---CPRGYRLDAEGARCVDRDECAQTGRCQAPCR 491
C C N+ G+FRC+ CP YR A + + G + CR
Sbjct: 534 HNCSINETCFNIQGAFRCLAFECPENYRRSAATQKSKKGRQNTPAGSSKEDCR 586
Score = 102 bits (244), Expect = 1e-21
Identities = 62/152 (40%), Positives = 78/152 (51%), Gaps = 16/152 (10%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-- 275
PC Q C +T C C GY+L DG +C DV+EC +H+C+ + C NT GS+ C
Sbjct: 185 PCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 244
Query: 276 --SCEDGYEKRGD-ACVDINECHEEGV--CPSPGRCVNLLGSFRC----VCPRGYRLDAE 428
SC GYE D +C DI+EC E G+ C C N LGSFRC C G+ DA
Sbjct: 245 DSSCGTGYELTEDNSCKDIDEC-ESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL 303
Query: 429 GARCVDRDECAQ-TGRCQA--PCRNYAGGYRC 515
G C+D +EC + C C N G Y C
Sbjct: 304 G-NCIDINECLSISAPCPIGHTCINTEGSYTC 334
>X53741-1|CAA37770.1| 566|Homo sapiens fibulin-1 A protein.
Length = 566
Score = 132 bits (319), Expect = 8e-31
Identities = 82/195 (42%), Positives = 98/195 (50%), Gaps = 15/195 (7%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPP-CDQLCHNTDGSYDCLCRTGYE 173
R VN+ GSFRC C GY G R +EC P C C NT GSY C C G+
Sbjct: 372 RCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFR 431
Query: 174 LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR---GDACVDINECH-EE 341
L DG +C D++EC + C Q C+N GSY+C C GY+ G C DI+EC
Sbjct: 432 LSVDGRSCEDINEC--SSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPT 489
Query: 342 GVCPSPGRCVNLLGSFRCVCP-RGYRLDAEGARCVDRDECAQTG--RC--QAPCRNYAGG 506
G RC+N+ GSF+C CP GYRL G C D DEC TG C C N G
Sbjct: 490 GGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECV-TGIHNCSINETCFNIQGA 548
Query: 507 YRC---DCPVGTVRS 542
+RC +CP RS
Sbjct: 549 FRCLAFECPENYRRS 563
Score = 124 bits (300), Expect = 2e-28
Identities = 81/204 (39%), Positives = 98/204 (48%), Gaps = 23/204 (11%)
Frame = +3
Query: 9 VNTIGSFRCV----CGPGYR-PAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCL---- 155
+NT+GSFRC CG GY + DEC C D +C NT GS+ C
Sbjct: 234 INTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 293
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-----SCEDGYE--KRGD 308
C++G+ D G NC D++EC + C C NTEGSY C +C GY + G
Sbjct: 294 CKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 309 ACVDINECHEEGV-CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGR-CQ 479
CVD++EC C RCVN GSFRC C GY D CVD +EC + GR C
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG 412
Query: 480 APCRNYAGGYRCDCPVGTVRSPSG 551
C N G Y C C VG S G
Sbjct: 413 HKCENTLGSYLCSCSVGFRLSVDG 436
Score = 117 bits (282), Expect = 2e-26
Identities = 65/151 (43%), Positives = 80/151 (52%), Gaps = 13/151 (8%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL-DE 182
NT+GS+ C C G+R + GR +EC+ PC Q C N GSY C CR GY+L D
Sbjct: 417 NTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCSQECANVYGSYQCYCRRGYQLSDV 474
Query: 183 DGANCRDVDECERDT--HTCQQICSNTEGSYECSC-EDGYE--KRGDACVDINECHEEGV 347
DG C D+DEC T H C C N GS++CSC GY G C DI+EC G+
Sbjct: 475 DGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDEC-VTGI 533
Query: 348 --CPSPGRCVNLLGSFRCV---CPRGYRLDA 425
C C N+ G+FRC+ CP YR A
Sbjct: 534 HNCSINETCFNIQGAFRCLAFECPENYRRSA 564
Score = 102 bits (244), Expect = 1e-21
Identities = 62/152 (40%), Positives = 78/152 (51%), Gaps = 16/152 (10%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-- 275
PC Q C +T C C GY+L DG +C DV+EC +H+C+ + C NT GS+ C
Sbjct: 185 PCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 244
Query: 276 --SCEDGYEKRGD-ACVDINECHEEGV--CPSPGRCVNLLGSFRC----VCPRGYRLDAE 428
SC GYE D +C DI+EC E G+ C C N LGSFRC C G+ DA
Sbjct: 245 DSSCGTGYELTEDNSCKDIDEC-ESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL 303
Query: 429 GARCVDRDECAQ-TGRCQA--PCRNYAGGYRC 515
G C+D +EC + C C N G Y C
Sbjct: 304 G-NCIDINECLSISAPCPIGHTCINTEGSYTC 334
>U01244-1|AAB17099.1| 703|Homo sapiens fibulin-1D protein.
Length = 703
Score = 132 bits (319), Expect = 8e-31
Identities = 82/195 (42%), Positives = 98/195 (50%), Gaps = 15/195 (7%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPP-CDQLCHNTDGSYDCLCRTGYE 173
R VN+ GSFRC C GY G R +EC P C C NT GSY C C G+
Sbjct: 372 RCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFR 431
Query: 174 LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR---GDACVDINECH-EE 341
L DG +C D++EC + C Q C+N GSY+C C GY+ G C DI+EC
Sbjct: 432 LSVDGRSCEDINEC--SSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPT 489
Query: 342 GVCPSPGRCVNLLGSFRCVCP-RGYRLDAEGARCVDRDECAQTG--RC--QAPCRNYAGG 506
G RC+N+ GSF+C CP GYRL G C D DEC TG C C N G
Sbjct: 490 GGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECV-TGIHNCSINETCFNIQGA 548
Query: 507 YRC---DCPVGTVRS 542
+RC +CP RS
Sbjct: 549 FRCLAFECPENYRRS 563
Score = 124 bits (300), Expect = 2e-28
Identities = 81/204 (39%), Positives = 98/204 (48%), Gaps = 23/204 (11%)
Frame = +3
Query: 9 VNTIGSFRCV----CGPGYR-PAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCL---- 155
+NT+GSFRC CG GY + DEC C D +C NT GS+ C
Sbjct: 234 INTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 293
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-----SCEDGYE--KRGD 308
C++G+ D G NC D++EC + C C NTEGSY C +C GY + G
Sbjct: 294 CKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 309 ACVDINECHEEGV-CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGR-CQ 479
CVD++EC C RCVN GSFRC C GY D CVD +EC + GR C
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG 412
Query: 480 APCRNYAGGYRCDCPVGTVRSPSG 551
C N G Y C C VG S G
Sbjct: 413 HKCENTLGSYLCSCSVGFRLSVDG 436
Score = 120 bits (289), Expect = 3e-27
Identities = 71/173 (41%), Positives = 87/173 (50%), Gaps = 13/173 (7%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL-DE 182
NT+GS+ C C G+R + GR +EC+ PC Q C N GSY C CR GY+L D
Sbjct: 417 NTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCSQECANVYGSYQCYCRRGYQLSDV 474
Query: 183 DGANCRDVDECERDT--HTCQQICSNTEGSYECSC-EDGYE--KRGDACVDINECHEEGV 347
DG C D+DEC T H C C N GS++CSC GY G C DI+EC G+
Sbjct: 475 DGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDEC-VTGI 533
Query: 348 --CPSPGRCVNLLGSFRCV---CPRGYRLDAEGARCVDRDECAQTGRCQAPCR 491
C C N+ G+FRC+ CP YR A + E T RC CR
Sbjct: 534 HNCSINETCFNIQGAFRCLAFECPENYRRSA----ATLQQEKTDTVRCIKSCR 582
Score = 102 bits (244), Expect = 1e-21
Identities = 62/152 (40%), Positives = 78/152 (51%), Gaps = 16/152 (10%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-- 275
PC Q C +T C C GY+L DG +C DV+EC +H+C+ + C NT GS+ C
Sbjct: 185 PCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 244
Query: 276 --SCEDGYEKRGD-ACVDINECHEEGV--CPSPGRCVNLLGSFRC----VCPRGYRLDAE 428
SC GYE D +C DI+EC E G+ C C N LGSFRC C G+ DA
Sbjct: 245 DSSCGTGYELTEDNSCKDIDEC-ESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL 303
Query: 429 GARCVDRDECAQ-TGRCQA--PCRNYAGGYRC 515
G C+D +EC + C C N G Y C
Sbjct: 304 G-NCIDINECLSISAPCPIGHTCINTEGSYTC 334
>AF126110-1|AAK37822.1| 703|Homo sapiens fibulin-1 isoform D
precursor protein.
Length = 703
Score = 132 bits (319), Expect = 8e-31
Identities = 82/195 (42%), Positives = 98/195 (50%), Gaps = 15/195 (7%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPP-CDQLCHNTDGSYDCLCRTGYE 173
R VN+ GSFRC C GY G R +EC P C C NT GSY C C G+
Sbjct: 372 RCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFR 431
Query: 174 LDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKR---GDACVDINECH-EE 341
L DG +C D++EC + C Q C+N GSY+C C GY+ G C DI+EC
Sbjct: 432 LSVDGRSCEDINEC--SSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPT 489
Query: 342 GVCPSPGRCVNLLGSFRCVCP-RGYRLDAEGARCVDRDECAQTG--RC--QAPCRNYAGG 506
G RC+N+ GSF+C CP GYRL G C D DEC TG C C N G
Sbjct: 490 GGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECV-TGIHNCSINETCFNIQGA 548
Query: 507 YRC---DCPVGTVRS 542
+RC +CP RS
Sbjct: 549 FRCLAFECPENYRRS 563
Score = 124 bits (300), Expect = 2e-28
Identities = 81/204 (39%), Positives = 98/204 (48%), Gaps = 23/204 (11%)
Frame = +3
Query: 9 VNTIGSFRCV----CGPGYR-PAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCL---- 155
+NT+GSFRC CG GY + DEC C D +C NT GS+ C
Sbjct: 234 INTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 293
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-----SCEDGYE--KRGD 308
C++G+ D G NC D++EC + C C NTEGSY C +C GY + G
Sbjct: 294 CKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 309 ACVDINECHEEGV-CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGR-CQ 479
CVD++EC C RCVN GSFRC C GY D CVD +EC + GR C
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG 412
Query: 480 APCRNYAGGYRCDCPVGTVRSPSG 551
C N G Y C C VG S G
Sbjct: 413 HKCENTLGSYLCSCSVGFRLSVDG 436
Score = 120 bits (289), Expect = 3e-27
Identities = 71/173 (41%), Positives = 87/173 (50%), Gaps = 13/173 (7%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL-DE 182
NT+GS+ C C G+R + GR +EC+ PC Q C N GSY C CR GY+L D
Sbjct: 417 NTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCSQECANVYGSYQCYCRRGYQLSDV 474
Query: 183 DGANCRDVDECERDT--HTCQQICSNTEGSYECSC-EDGYE--KRGDACVDINECHEEGV 347
DG C D+DEC T H C C N GS++CSC GY G C DI+EC G+
Sbjct: 475 DGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDEC-VTGI 533
Query: 348 --CPSPGRCVNLLGSFRCV---CPRGYRLDAEGARCVDRDECAQTGRCQAPCR 491
C C N+ G+FRC+ CP YR A + E T RC CR
Sbjct: 534 HNCSINETCFNIQGAFRCLAFECPENYRRSA----ATLQQEKTDTVRCIKSCR 582
Score = 102 bits (244), Expect = 1e-21
Identities = 62/152 (40%), Positives = 78/152 (51%), Gaps = 16/152 (10%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYEC-- 275
PC Q C +T C C GY+L DG +C DV+EC +H+C+ + C NT GS+ C
Sbjct: 185 PCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR 244
Query: 276 --SCEDGYEKRGD-ACVDINECHEEGV--CPSPGRCVNLLGSFRC----VCPRGYRLDAE 428
SC GYE D +C DI+EC E G+ C C N LGSFRC C G+ DA
Sbjct: 245 DSSCGTGYELTEDNSCKDIDEC-ESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL 303
Query: 429 GARCVDRDECAQ-TGRCQA--PCRNYAGGYRC 515
G C+D +EC + C C N G Y C
Sbjct: 304 G-NCIDINECLSISAPCPIGHTCINTEGSYTC 334
>Z97832-1|CAI20187.1| 993|Homo sapiens protein ( Human DNA sequence
from clone RP3-329A5 on chromosome 6p21.1-21.33
Contains the gene for a novel EGF-like and CUB domain
protein ).
Length = 993
Score = 131 bits (317), Expect = 1e-30
Identities = 68/173 (39%), Positives = 85/173 (49%), Gaps = 3/173 (1%)
Frame = +3
Query: 30 RCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
RC C + G + CAV CD CH+ C C G+ L D C+D+D
Sbjct: 220 RCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDID 279
Query: 210 ECERDTHTCQQICSNTEGSYECSCEDGYEK--RGDACVDINECHEEGVCPSPGRCVNLLG 383
EC + C IC NT GS+ECSC+ GY+ C DI+EC + C CVN G
Sbjct: 280 ECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDIDECSFDRTCDH--ICVNTPG 337
Query: 384 SFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRCDCPVGTVR 539
SF+C+C RGY L C D DEC+ G C+ C N G Y+C CP G R
Sbjct: 338 SFQCLCHRGYLLYGI-THCGDVDECSINRGGCRFGCINTPGSYQCTCPAGQGR 389
Score = 114 bits (275), Expect = 2e-25
Identities = 63/161 (39%), Positives = 81/161 (50%), Gaps = 12/161 (7%)
Frame = +3
Query: 84 DECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECER-DTHTCQQICSN 254
DEC C D +C NT SY C+C++GY DG +C+DVDECER D C C N
Sbjct: 31 DECVEGTDNCHIDAICQNTPRSYKCICKSGY--TGDGKHCKDVDECEREDNAGCVHDCVN 88
Query: 255 TEGSYECSCEDGYEKRGDA--CVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDA 425
G+Y C+C DG+ D C+D++EC E G C CVN++GS+ C C G+ L
Sbjct: 89 IPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQ--SCVNMMGSYECHCREGFFLSD 146
Query: 426 EGARCVDRDE----CAQTGR-CQAPCRNY-AGGYRCDCPVG 530
C+ R E C C CR GG C+C G
Sbjct: 147 NQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPG 187
Score = 107 bits (258), Expect = 2e-23
Identities = 49/114 (42%), Positives = 61/114 (53%), Gaps = 3/114 (2%)
Frame = +3
Query: 198 RDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCV 371
+DVDEC T C IC NT SY+C C+ GY G C D++EC E CV
Sbjct: 28 QDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKHCKDVDECEREDNAGCVHDCV 87
Query: 372 NLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGRCQAPCRNYAGGYRCDCPVG 530
N+ G++RC C G+ L +G C+D DECA+ G CQ C N G Y C C G
Sbjct: 88 NIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREG 141
Score = 103 bits (248), Expect = 3e-22
Identities = 62/188 (32%), Positives = 79/188 (42%), Gaps = 8/188 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPP-CDQLCHNTDGSYDCLCRTGYELDEDG 188
NT S++C+C GY G+ + DEC C C N G+Y C C G+ L DG
Sbjct: 48 NTPRSYKCICKSGYTGDGKHCKDVDECEREDNAGCVHDCVNIPGNYRCTCYDGFHLAHDG 107
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGR- 365
NC DVDEC CQQ C N GSYEC C +G+ + I E C +
Sbjct: 108 HNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHG 167
Query: 366 CVNLL-----GSFRCVCPRGYRLDAEGARCVDRDECAQ-TGRCQAPCRNYAGGYRCDCPV 527
C ++ G C C G+ L C + C G CQ C + G RC C +
Sbjct: 168 CAHICRETPKGGIACECRPGFELTKNQRDC--KLTCNYGNGGCQHTCDDTEQGPRCGCHI 225
Query: 528 GTVRSPSG 551
V G
Sbjct: 226 KFVLHTDG 233
Score = 95.1 bits (226), Expect = 1e-19
Identities = 62/190 (32%), Positives = 82/190 (43%), Gaps = 11/190 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN G++RC C G+ A G DECA C Q C N GSY+C CR G+ L +
Sbjct: 87 VNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSD 146
Query: 183 DGANCRDVDE----CERDTHTCQQICSNT-EGSYECSCEDGYE---KRGDACVDINECHE 338
+ C E C H C IC T +G C C G+E + D + N +
Sbjct: 147 NQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLTCN--YG 204
Query: 339 EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRC 515
G C C + RC C + L +G C++ CA G C + C + A G C
Sbjct: 205 NGGCQHT--CDDTEQGPRCGCHIKFVLHTDGKTCIET--CAVNNGGCDSKCHDAATGVHC 260
Query: 516 DCPVGTVRSP 545
CPVG + P
Sbjct: 261 TCPVGFMLQP 270
Score = 85.8 bits (203), Expect = 9e-17
Identities = 55/149 (36%), Positives = 71/149 (47%), Gaps = 3/149 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT+GSF C C GY+ R + DEC+ CD +C NT GS+ CLC GY L
Sbjct: 294 NTVGSFECSCKKGYKLLINERNCQDIDECSF-DRTCDHICVNTPGSFQCLCHRGYLL-YG 351
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCP-SPG 362
+C DVDEC + C+ C NT GSY+C+C G +G + +C E C SPG
Sbjct: 352 ITHCGDVDECSINRGGCRFGCINTPGSYQCTCPAG---QGRLHWNGKDCTEPLKCQGSPG 408
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDR 449
+L C R + D C R
Sbjct: 409 ASKAMLS-----CNRSGKKDTCALTCPSR 432
Score = 53.2 bits (122), Expect = 6e-07
Identities = 31/93 (33%), Positives = 44/93 (47%), Gaps = 2/93 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGR-DECAVRPPPCDQLCHNTDGSYDCLCRTGY-ELDE 182
VNT GSF+C+C GY G G DEC++ C C NT GSY C C G L
Sbjct: 333 VNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCRFGCINTPGSYQCTCPAGQGRLHW 392
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSC 281
+G +C + +C+ + + S + +C
Sbjct: 393 NGKDCTEPLKCQGSPGASKAMLSCNRSGKKDTC 425
>AY639608-1|AAU08347.1| 993|Homo sapiens signal peptide, CUB and
EGF-like domain containing protein 3 protein.
Length = 993
Score = 131 bits (317), Expect = 1e-30
Identities = 68/173 (39%), Positives = 85/173 (49%), Gaps = 3/173 (1%)
Frame = +3
Query: 30 RCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
RC C + G + CAV CD CH+ C C G+ L D C+D+D
Sbjct: 220 RCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDID 279
Query: 210 ECERDTHTCQQICSNTEGSYECSCEDGYEK--RGDACVDINECHEEGVCPSPGRCVNLLG 383
EC + C IC NT GS+ECSC+ GY+ C DI+EC + C CVN G
Sbjct: 280 ECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDIDECSFDRTCDH--ICVNTPG 337
Query: 384 SFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRCDCPVGTVR 539
SF+C+C RGY L C D DEC+ G C+ C N G Y+C CP G R
Sbjct: 338 SFQCLCHRGYLLYGI-THCGDVDECSINRGGCRFGCINTPGSYQCTCPAGQGR 389
Score = 114 bits (275), Expect = 2e-25
Identities = 63/161 (39%), Positives = 81/161 (50%), Gaps = 12/161 (7%)
Frame = +3
Query: 84 DECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECER-DTHTCQQICSN 254
DEC C D +C NT SY C+C++GY DG +C+DVDECER D C C N
Sbjct: 31 DECVEGTDNCHIDAICQNTPRSYKCICKSGY--TGDGKHCKDVDECEREDNAGCVHDCVN 88
Query: 255 TEGSYECSCEDGYEKRGDA--CVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDA 425
G+Y C+C DG+ D C+D++EC E G C CVN++GS+ C C G+ L
Sbjct: 89 IPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQ--SCVNMMGSYECHCREGFFLSD 146
Query: 426 EGARCVDRDE----CAQTGR-CQAPCRNY-AGGYRCDCPVG 530
C+ R E C C CR GG C+C G
Sbjct: 147 NQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPG 187
Score = 107 bits (258), Expect = 2e-23
Identities = 49/114 (42%), Positives = 61/114 (53%), Gaps = 3/114 (2%)
Frame = +3
Query: 198 RDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCV 371
+DVDEC T C IC NT SY+C C+ GY G C D++EC E CV
Sbjct: 28 QDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKHCKDVDECEREDNAGCVHDCV 87
Query: 372 NLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGRCQAPCRNYAGGYRCDCPVG 530
N+ G++RC C G+ L +G C+D DECA+ G CQ C N G Y C C G
Sbjct: 88 NIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREG 141
Score = 103 bits (248), Expect = 3e-22
Identities = 62/188 (32%), Positives = 79/188 (42%), Gaps = 8/188 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPP-CDQLCHNTDGSYDCLCRTGYELDEDG 188
NT S++C+C GY G+ + DEC C C N G+Y C C G+ L DG
Sbjct: 48 NTPRSYKCICKSGYTGDGKHCKDVDECEREDNAGCVHDCVNIPGNYRCTCYDGFHLAHDG 107
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGR- 365
NC DVDEC CQQ C N GSYEC C +G+ + I E C +
Sbjct: 108 HNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHG 167
Query: 366 CVNLL-----GSFRCVCPRGYRLDAEGARCVDRDECAQ-TGRCQAPCRNYAGGYRCDCPV 527
C ++ G C C G+ L C + C G CQ C + G RC C +
Sbjct: 168 CAHICRETPKGGIACECRPGFELTKNQRDC--KLTCNYGNGGCQHTCDDTEQGPRCGCHI 225
Query: 528 GTVRSPSG 551
V G
Sbjct: 226 KFVLHTDG 233
Score = 95.1 bits (226), Expect = 1e-19
Identities = 62/190 (32%), Positives = 82/190 (43%), Gaps = 11/190 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN G++RC C G+ A G DECA C Q C N GSY+C CR G+ L +
Sbjct: 87 VNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSD 146
Query: 183 DGANCRDVDE----CERDTHTCQQICSNT-EGSYECSCEDGYE---KRGDACVDINECHE 338
+ C E C H C IC T +G C C G+E + D + N +
Sbjct: 147 NQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLTCN--YG 204
Query: 339 EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRC 515
G C C + RC C + L +G C++ CA G C + C + A G C
Sbjct: 205 NGGCQHT--CDDTEQGPRCGCHIKFVLHTDGKTCIET--CAVNNGGCDSKCHDAATGVHC 260
Query: 516 DCPVGTVRSP 545
CPVG + P
Sbjct: 261 TCPVGFMLQP 270
Score = 85.8 bits (203), Expect = 9e-17
Identities = 55/149 (36%), Positives = 71/149 (47%), Gaps = 3/149 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT+GSF C C GY+ R + DEC+ CD +C NT GS+ CLC GY L
Sbjct: 294 NTVGSFECSCKKGYKLLINERNCQDIDECSF-DRTCDHICVNTPGSFQCLCHRGYLL-YG 351
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCP-SPG 362
+C DVDEC + C+ C NT GSY+C+C G +G + +C E C SPG
Sbjct: 352 ITHCGDVDECSINRGGCRFGCINTPGSYQCTCPAG---QGRLHWNGKDCTEPLKCQGSPG 408
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDR 449
+L C R + D C R
Sbjct: 409 ASKAMLS-----CNRSGKKDTCALTCPSR 432
Score = 53.2 bits (122), Expect = 6e-07
Identities = 31/93 (33%), Positives = 44/93 (47%), Gaps = 2/93 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGR-DECAVRPPPCDQLCHNTDGSYDCLCRTGY-ELDE 182
VNT GSF+C+C GY G G DEC++ C C NT GSY C C G L
Sbjct: 333 VNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCRFGCINTPGSYQCTCPAGQGRLHW 392
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSC 281
+G +C + +C+ + + S + +C
Sbjct: 393 NGKDCTEPLKCQGSPGASKAMLSCNRSGKKDTC 425
>AF452494-1|AAN76808.1| 993|Homo sapiens CUB and EGF containing
protein protein.
Length = 993
Score = 131 bits (317), Expect = 1e-30
Identities = 68/173 (39%), Positives = 85/173 (49%), Gaps = 3/173 (1%)
Frame = +3
Query: 30 RCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
RC C + G + CAV CD CH+ C C G+ L D C+D+D
Sbjct: 220 RCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDID 279
Query: 210 ECERDTHTCQQICSNTEGSYECSCEDGYEK--RGDACVDINECHEEGVCPSPGRCVNLLG 383
EC + C IC NT GS+ECSC+ GY+ C DI+EC + C CVN G
Sbjct: 280 ECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDIDECSFDRTCDH--ICVNTPG 337
Query: 384 SFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRCDCPVGTVR 539
SF+C+C RGY L C D DEC+ G C+ C N G Y+C CP G R
Sbjct: 338 SFQCLCHRGYLLYGI-THCGDVDECSINRGGCRFGCINTPGSYQCTCPAGQGR 389
Score = 114 bits (275), Expect = 2e-25
Identities = 63/161 (39%), Positives = 81/161 (50%), Gaps = 12/161 (7%)
Frame = +3
Query: 84 DECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECER-DTHTCQQICSN 254
DEC C D +C NT SY C+C++GY DG +C+DVDECER D C C N
Sbjct: 31 DECVEGTDNCHIDAICQNTPRSYKCICKSGY--TGDGKHCKDVDECEREDNAGCVHDCVN 88
Query: 255 TEGSYECSCEDGYEKRGDA--CVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDA 425
G+Y C+C DG+ D C+D++EC E G C CVN++GS+ C C G+ L
Sbjct: 89 IPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQ--SCVNMMGSYECHCREGFFLSD 146
Query: 426 EGARCVDRDE----CAQTGR-CQAPCRNY-AGGYRCDCPVG 530
C+ R E C C CR GG C+C G
Sbjct: 147 NQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPG 187
Score = 107 bits (258), Expect = 2e-23
Identities = 49/114 (42%), Positives = 61/114 (53%), Gaps = 3/114 (2%)
Frame = +3
Query: 198 RDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCV 371
+DVDEC T C IC NT SY+C C+ GY G C D++EC E CV
Sbjct: 28 QDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKHCKDVDECEREDNAGCVHDCV 87
Query: 372 NLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGRCQAPCRNYAGGYRCDCPVG 530
N+ G++RC C G+ L +G C+D DECA+ G CQ C N G Y C C G
Sbjct: 88 NIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREG 141
Score = 103 bits (248), Expect = 3e-22
Identities = 62/188 (32%), Positives = 79/188 (42%), Gaps = 8/188 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPP-CDQLCHNTDGSYDCLCRTGYELDEDG 188
NT S++C+C GY G+ + DEC C C N G+Y C C G+ L DG
Sbjct: 48 NTPRSYKCICKSGYTGDGKHCKDVDECEREDNAGCVHDCVNIPGNYRCTCYDGFHLAHDG 107
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGR- 365
NC DVDEC CQQ C N GSYEC C +G+ + I E C +
Sbjct: 108 HNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHG 167
Query: 366 CVNLL-----GSFRCVCPRGYRLDAEGARCVDRDECAQ-TGRCQAPCRNYAGGYRCDCPV 527
C ++ G C C G+ L C + C G CQ C + G RC C +
Sbjct: 168 CAHICRETPKGGIACECRPGFELTKNQRDC--KLTCNYGNGGCQHTCDDTEQGPRCGCHI 225
Query: 528 GTVRSPSG 551
V G
Sbjct: 226 KFVLHTDG 233
Score = 95.1 bits (226), Expect = 1e-19
Identities = 62/190 (32%), Positives = 82/190 (43%), Gaps = 11/190 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN G++RC C G+ A G DECA C Q C N GSY+C CR G+ L +
Sbjct: 87 VNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSD 146
Query: 183 DGANCRDVDE----CERDTHTCQQICSNT-EGSYECSCEDGYE---KRGDACVDINECHE 338
+ C E C H C IC T +G C C G+E + D + N +
Sbjct: 147 NQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLTCN--YG 204
Query: 339 EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRC 515
G C C + RC C + L +G C++ CA G C + C + A G C
Sbjct: 205 NGGCQHT--CDDTEQGPRCGCHIKFVLHTDGKTCIET--CAVNNGGCDSKCHDAATGVHC 260
Query: 516 DCPVGTVRSP 545
CPVG + P
Sbjct: 261 TCPVGFMLQP 270
Score = 85.8 bits (203), Expect = 9e-17
Identities = 55/149 (36%), Positives = 71/149 (47%), Gaps = 3/149 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT+GSF C C GY+ R + DEC+ CD +C NT GS+ CLC GY L
Sbjct: 294 NTVGSFECSCKKGYKLLINERNCQDIDECSF-DRTCDHICVNTPGSFQCLCHRGYLL-YG 351
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCP-SPG 362
+C DVDEC + C+ C NT GSY+C+C G +G + +C E C SPG
Sbjct: 352 ITHCGDVDECSINRGGCRFGCINTPGSYQCTCPAG---QGRLHWNGKDCTEPLKCQGSPG 408
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDR 449
+L C R + D C R
Sbjct: 409 ASKAMLS-----CNRSGKKDTCALTCPSR 432
Score = 53.2 bits (122), Expect = 6e-07
Identities = 31/93 (33%), Positives = 44/93 (47%), Gaps = 2/93 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGR-DECAVRPPPCDQLCHNTDGSYDCLCRTGY-ELDE 182
VNT GSF+C+C GY G G DEC++ C C NT GSY C C G L
Sbjct: 333 VNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCRFGCINTPGSYQCTCPAGQGRLHW 392
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSC 281
+G +C + +C+ + + S + +C
Sbjct: 393 NGKDCTEPLKCQGSPGASKAMLSCNRSGKKDTC 425
>AK092062-1|BAC03798.1| 880|Homo sapiens protein ( Homo sapiens
cDNA FLJ34743 fis, clone MESAN2009019, moderately
similar to CEGP1 protein. ).
Length = 880
Score = 131 bits (316), Expect = 2e-30
Identities = 64/155 (41%), Positives = 80/155 (51%), Gaps = 3/155 (1%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEG 263
+ CAV CD CH+ C C G+ L D C+D+DEC + C IC NT G
Sbjct: 125 ETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVG 184
Query: 264 SYECSCEDGYEK--RGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGAR 437
S+ECSC+ GY+ C DI+EC + C CVN GSF+C+C RGY L
Sbjct: 185 SFECSCKKGYKLLINERNCQDIDECSFDRTCDH--ICVNTPGSFQCLCHRGYLLYGI-TH 241
Query: 438 CVDRDECA-QTGRCQAPCRNYAGGYRCDCPVGTVR 539
C D DEC+ G C+ C N G Y+C CP G R
Sbjct: 242 CGDVDECSINRGGCRFGCINTPGSYQCTCPAGQGR 276
Score = 116 bits (279), Expect = 6e-26
Identities = 58/147 (39%), Positives = 80/147 (54%), Gaps = 5/147 (3%)
Frame = +3
Query: 33 CVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDV 206
C C G+ +P + + DEC + CD +C NT GS++C C+ GY+L + NC+D+
Sbjct: 147 CTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDI 206
Query: 207 DECERDTHTCQQICSNTEGSYECSCEDGYEKRG-DACVDINECH-EEGVCPSPGRCVNLL 380
DEC D TC IC NT GS++C C GY G C D++EC G C C+N
Sbjct: 207 DECSFD-RTCDHICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCRF--GCINTP 263
Query: 381 GSFRCVCPRGY-RLDAEGARCVDRDEC 458
GS++C CP G RL G C + +C
Sbjct: 264 GSYQCTCPAGQGRLHWNGKDCTEPLKC 290
Score = 85.8 bits (203), Expect = 9e-17
Identities = 55/149 (36%), Positives = 71/149 (47%), Gaps = 3/149 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT+GSF C C GY+ R + DEC+ CD +C NT GS+ CLC GY L
Sbjct: 181 NTVGSFECSCKKGYKLLINERNCQDIDECSF-DRTCDHICVNTPGSFQCLCHRGYLL-YG 238
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCP-SPG 362
+C DVDEC + C+ C NT GSY+C+C G +G + +C E C SPG
Sbjct: 239 ITHCGDVDECSINRGGCRFGCINTPGSYQCTCPAG---QGRLHWNGKDCTEPLKCQGSPG 295
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDR 449
+L C R + D C R
Sbjct: 296 ASKAMLS-----CNRSGKKDTCALTCPSR 319
Score = 59.7 bits (138), Expect = 7e-09
Identities = 46/159 (28%), Positives = 62/159 (38%), Gaps = 23/159 (14%)
Frame = +3
Query: 138 GSYDCLCRTGYELDEDGANCRDVDE----CERDTHTCQQICSNT-EGSYECSCEDGYE-- 296
GSY+C CR G+ L ++ C E C H C IC T +G C C G+E
Sbjct: 3 GSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELT 62
Query: 297 -KRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC----------- 440
+ D + N + G C C + RC C + L +G C
Sbjct: 63 KNQRDCKLTCN--YGNGGCQHT--CDDTEQGPRCGCHIKFVLHTDGKTCIGERRLEQHIP 118
Query: 441 ---VDRDECA-QTGRCQAPCRNYAGGYRCDCPVGTVRSP 545
V + CA G C + C + A G C CPVG + P
Sbjct: 119 TQAVSNETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQP 157
Score = 53.2 bits (122), Expect = 6e-07
Identities = 31/93 (33%), Positives = 44/93 (47%), Gaps = 2/93 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGR-DECAVRPPPCDQLCHNTDGSYDCLCRTGY-ELDE 182
VNT GSF+C+C GY G G DEC++ C C NT GSY C C G L
Sbjct: 220 VNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCRFGCINTPGSYQCTCPAGQGRLHW 279
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSC 281
+G +C + +C+ + + S + +C
Sbjct: 280 NGKDCTEPLKCQGSPGASKAMLSCNRSGKKDTC 312
Score = 36.3 bits (80), Expect = 0.072
Identities = 28/104 (26%), Positives = 38/104 (36%), Gaps = 7/104 (6%)
Frame = +3
Query: 261 GSYECSCEDGYEKRGDACVDINECHEEGVCPSPGR-CVNLL-----GSFRCVCPRGYRLD 422
GSYEC C +G+ + I E C + C ++ G C C G+ L
Sbjct: 3 GSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELT 62
Query: 423 AEGARCVDRDECAQ-TGRCQAPCRNYAGGYRCDCPVGTVRSPSG 551
C + C G CQ C + G RC C + V G
Sbjct: 63 KNQRDC--KLTCNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDG 104
Score = 31.5 bits (68), Expect = 2.0
Identities = 18/58 (31%), Positives = 24/58 (41%), Gaps = 6/58 (10%)
Frame = +3
Query: 375 LLGSFRCVCPRGYRLDAEGARCVDRDE----CAQTGR-CQAPCRNY-AGGYRCDCPVG 530
++GS+ C C G+ L C+ R E C C CR GG C+C G
Sbjct: 1 MMGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPG 58
>BC052263-1|AAH52263.2| 992|Homo sapiens signal peptide, CUB
domain, EGF-like 3 protein.
Length = 992
Score = 130 bits (315), Expect = 2e-30
Identities = 68/173 (39%), Positives = 85/173 (49%), Gaps = 3/173 (1%)
Frame = +3
Query: 30 RCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
RC C + G + CAV CD CH+ C C G+ L D C+D+D
Sbjct: 219 RCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHDAAIGVHCTCPVGFMLQPDRKTCKDID 278
Query: 210 ECERDTHTCQQICSNTEGSYECSCEDGYEK--RGDACVDINECHEEGVCPSPGRCVNLLG 383
EC + C IC NT GS+ECSC+ GY+ C DI+EC + C CVN G
Sbjct: 279 ECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDIDECSFDRTCDH--ICVNTPG 336
Query: 384 SFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRCDCPVGTVR 539
SF+C+C RGY L C D DEC+ G C+ C N G Y+C CP G R
Sbjct: 337 SFQCLCHRGYLLYGI-THCGDVDECSINRGGCRFGCINTPGSYQCTCPAGQGR 388
Score = 115 bits (277), Expect = 1e-25
Identities = 63/160 (39%), Positives = 81/160 (50%), Gaps = 11/160 (6%)
Frame = +3
Query: 84 DECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECER-DTHTCQQICSN 254
DEC C D +C NT SY C+C++GY DG +C+DVDECER D C C N
Sbjct: 31 DECVEGTDNCHIDAICQNTPRSYKCICKSGY--TGDGKHCKDVDECEREDNAGCVHDCVN 88
Query: 255 TEGSYECSCEDGYEKRGDA--CVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDA 425
G+Y C+C DG+ D C+D++EC E G C CVN++GS+ C C G+ L
Sbjct: 89 IPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQ--SCVNMMGSYECHCREGFFLSD 146
Query: 426 EGARCVDRDE---CAQTGR-CQAPCRNY-AGGYRCDCPVG 530
C+ R E C C CR GG C+C G
Sbjct: 147 NQHTCIQRPEGMNCMNKNHGCAHICRETPKGGIACECRPG 186
Score = 107 bits (258), Expect = 2e-23
Identities = 49/114 (42%), Positives = 61/114 (53%), Gaps = 3/114 (2%)
Frame = +3
Query: 198 RDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCV 371
+DVDEC T C IC NT SY+C C+ GY G C D++EC E CV
Sbjct: 28 QDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKHCKDVDECEREDNAGCVHDCV 87
Query: 372 NLLGSFRCVCPRGYRLDAEGARCVDRDECAQ-TGRCQAPCRNYAGGYRCDCPVG 530
N+ G++RC C G+ L +G C+D DECA+ G CQ C N G Y C C G
Sbjct: 88 NIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREG 141
Score = 101 bits (241), Expect = 2e-21
Identities = 60/187 (32%), Positives = 76/187 (40%), Gaps = 7/187 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPP-CDQLCHNTDGSYDCLCRTGYELDEDG 188
NT S++C+C GY G+ + DEC C C N G+Y C C G+ L DG
Sbjct: 48 NTPRSYKCICKSGYTGDGKHCKDVDECEREDNAGCVHDCVNIPGNYRCTCYDGFHLAHDG 107
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRC 368
NC DVDEC CQQ C N GSYEC C +G+ + I C
Sbjct: 108 HNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTCIQRPEGMNCMNKNHGC 167
Query: 369 VNLL-----GSFRCVCPRGYRLDAEGARCVDRDECAQ-TGRCQAPCRNYAGGYRCDCPVG 530
++ G C C G+ L C + C G CQ C + G RC C +
Sbjct: 168 AHICRETPKGGIACECRPGFELTKNQRDC--KLTCNYGNGGCQHTCDDTEQGPRCGCHIK 225
Query: 531 TVRSPSG 551
V G
Sbjct: 226 FVLHTDG 232
Score = 95.1 bits (226), Expect = 1e-19
Identities = 62/189 (32%), Positives = 82/189 (43%), Gaps = 10/189 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN G++RC C G+ A G DECA C Q C N GSY+C CR G+ L +
Sbjct: 87 VNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSD 146
Query: 183 DGANCRDVDE---CERDTHTCQQICSNT-EGSYECSCEDGYE---KRGDACVDINECHEE 341
+ C E C H C IC T +G C C G+E + D + N +
Sbjct: 147 NQHTCIQRPEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLTCN--YGN 204
Query: 342 GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRCD 518
G C C + RC C + L +G C++ CA G C + C + A G C
Sbjct: 205 GGCQHT--CDDTEQGPRCGCHIKFVLHTDGKTCIET--CAVNNGGCDSKCHDAAIGVHCT 260
Query: 519 CPVGTVRSP 545
CPVG + P
Sbjct: 261 CPVGFMLQP 269
Score = 85.8 bits (203), Expect = 9e-17
Identities = 55/149 (36%), Positives = 71/149 (47%), Gaps = 3/149 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT+GSF C C GY+ R + DEC+ CD +C NT GS+ CLC GY L
Sbjct: 293 NTVGSFECSCKKGYKLLINERNCQDIDECSF-DRTCDHICVNTPGSFQCLCHRGYLL-YG 350
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCP-SPG 362
+C DVDEC + C+ C NT GSY+C+C G +G + +C E C SPG
Sbjct: 351 ITHCGDVDECSINRGGCRFGCINTPGSYQCTCPAG---QGRLHWNGKDCTEPLKCQGSPG 407
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDR 449
+L C R + D C R
Sbjct: 408 ASKAMLS-----CNRSGKKDTCALTCPSR 431
Score = 53.2 bits (122), Expect = 6e-07
Identities = 31/93 (33%), Positives = 44/93 (47%), Gaps = 2/93 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGR-DECAVRPPPCDQLCHNTDGSYDCLCRTGY-ELDE 182
VNT GSF+C+C GY G G DEC++ C C NT GSY C C G L
Sbjct: 332 VNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCRFGCINTPGSYQCTCPAGQGRLHW 391
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSC 281
+G +C + +C+ + + S + +C
Sbjct: 392 NGKDCTEPLKCQGSPGASKAMLSCNRSGKKDTC 424
>AY358895-1|AAQ89254.1| 915|Homo sapiens MATN2 protein.
Length = 915
Score = 130 bits (315), Expect = 2e-30
Identities = 70/182 (38%), Positives = 86/182 (47%), Gaps = 8/182 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+N GS+ C C GY R +D CA+ C+QLC N GS+ C C +GY L E
Sbjct: 254 INIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALAE 313
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPS 356
DG C VD C + H C+ C N +GSY C C +G+ D C IN C
Sbjct: 314 DGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDEKTCTRINYC----ALNK 369
Query: 357 PG---RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQAPCRNYAGGYRCDCP 524
PG CVN+ S+ C C RGY LD G C D CAQ C+ C N + C C
Sbjct: 370 PGCEHECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCS 429
Query: 525 VG 530
G
Sbjct: 430 EG 431
Score = 121 bits (291), Expect = 2e-27
Identities = 63/187 (33%), Positives = 88/187 (47%), Gaps = 6/187 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN GS+ C C G+ P + + CA+ P C+ C N + SY C C GY LD
Sbjct: 336 VNADGSYLCQCHEGFALNPDEKTCTRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDP 395
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINEC-HEEGVCP 353
+G C VD C + H C+Q+C NTE S+ C C +G+ D C ++ C + C
Sbjct: 396 NGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCE 455
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQAPCRNYAGGYRCDCPVG 530
CVN+ SF C CP G+ L ++G C D CA C+ C + + C C G
Sbjct: 456 Y--SCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEG 513
Query: 531 TVRSPSG 551
+ G
Sbjct: 514 YILREDG 520
Score = 108 bits (259), Expect = 1e-23
Identities = 54/157 (34%), Positives = 71/157 (45%), Gaps = 3/157 (1%)
Frame = +3
Query: 90 CAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSY 269
C+ C C N GSY C C+ GY L+ D CR D C + H C+Q+C N GS+
Sbjct: 242 CSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSF 301
Query: 270 ECSCEDGY--EKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCV 443
C C GY + G CV ++ C E CVN GS+ C C G+ L+ + C
Sbjct: 302 VCQCYSGYALAEDGKRCVAVDYCASEN-HGCEHECVNADGSYLCQCHEGFALNPDEKTCT 360
Query: 444 DRDECA-QTGRCQAPCRNYAGGYRCDCPVGTVRSPSG 551
+ CA C+ C N Y C C G P+G
Sbjct: 361 RINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNG 397
Score = 108 bits (259), Expect = 1e-23
Identities = 61/189 (32%), Positives = 82/189 (43%), Gaps = 8/189 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+NT SF C C G+ + D C + C+ C N D S+ C C G+ L
Sbjct: 418 LNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRS 477
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPG 362
DG C +D C H C+ C ++E S+ C C +GY R D C + VC +
Sbjct: 478 DGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDG----KTCRRKDVCQAID 533
Query: 363 R-----CVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQAPCRNYAGGYRCDCP 524
CVN S+ C C G+RL +G RC +D C T C+ C N Y C C
Sbjct: 534 HGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCS 593
Query: 525 VGTVRSPSG 551
G V + G
Sbjct: 594 EGFVLAEDG 602
Score = 99.1 bits (236), Expect = 9e-21
Identities = 53/151 (35%), Positives = 71/151 (47%), Gaps = 7/151 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN SF C C G+ R G+ D CA+ C+ C +++ S+ C C GY L E
Sbjct: 459 VNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILRE 518
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPG 362
DG CR D C+ H C+ IC N++ SY C C +G+ D C + VC S
Sbjct: 519 DGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDG----KRCRRKDVCKSTH 574
Query: 363 R-----CVNLLGSFRCVCPRGYRLDAEGARC 440
CVN S+ C C G+ L +G RC
Sbjct: 575 HGCEHICVNNGNSYICKCSEGFVLAEDGRRC 605
Score = 53.6 bits (123), Expect = 4e-07
Identities = 26/70 (37%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN+ S+ C C G+R A G+ R +D C C+ +C N SY C C G+ L E
Sbjct: 541 VNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAE 600
Query: 183 DGANCRDVDE 212
DG C+ E
Sbjct: 601 DGRRCKKCTE 610
>CR541934-1|CAG46732.1| 443|Homo sapiens EFEMP2 protein.
Length = 443
Score = 130 bits (313), Expect = 4e-30
Identities = 69/170 (40%), Positives = 83/170 (48%), Gaps = 6/170 (3%)
Frame = +3
Query: 39 CGPGYRPAGR-GVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C PGY P + DECA C Q CHN GSY C C GY + G C D+D
Sbjct: 109 CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYR--KIGPECVDID 166
Query: 210 ECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPSPGRCVNLLG 383
EC CQ C N GS+ C CE G++ +CVD+NEC C RC N G
Sbjct: 167 ECR--YRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQ--RCFNSYG 222
Query: 384 SFRCVCPRGYRLDAEGARCVDRDECAQTG-RCQAPCRNYAGGYRCDCPVG 530
+F C C +GY L +G C D DEC+ + CQ C N G + C CP G
Sbjct: 223 TFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQG 272
Score = 127 bits (307), Expect = 2e-29
Identities = 70/174 (40%), Positives = 93/174 (53%), Gaps = 6/174 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N GS++C C GYR G DEC R C C N GS+ C C G++L +
Sbjct: 142 NLPGSYQCTCPDGYRKIGPECVDIDECRYRY--CQHRCVNLPGSFRCQCEPGFQLGPNNR 199
Query: 192 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINEC-HEEGVCPSPG 362
+C DV+EC+ C+Q C N+ G++ C C GYE + G +C DI+EC + +C
Sbjct: 200 SCVDVNECDMGA-PCEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQY-- 256
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQ--APCRNYAGGYRC 515
RCVN G F C CP+GY+L A C D DEC + +C C N+ GGYRC
Sbjct: 257 RCVNEPGRFSCHCPQGYQLLAT-RLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 118 bits (284), Expect = 1e-26
Identities = 65/169 (38%), Positives = 83/169 (49%), Gaps = 5/169 (2%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
R VN GSFRC C PG++ P R +EC + P C+Q C N+ G++ C C GYEL
Sbjct: 176 RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAP-CEQRCFNSYGTFLCRCHQGYEL 234
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD-ACVDINECHEEGV-- 347
DG +C D+DEC ++ CQ C N G + C C GY+ C DI+EC E G
Sbjct: 235 HRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDEC-ESGAHQ 293
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRN 494
C CVN G +RCV + RCV+ RC P N
Sbjct: 294 CSEAQTCVNFHGGYRCV---------DTNRCVEPYIQVSENRCLCPASN 333
Score = 75.4 bits (177), Expect = 1e-13
Identities = 56/176 (31%), Positives = 72/176 (40%), Gaps = 4/176 (2%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDV 206
C G + P + R +EC P C + C N G Y CL R+ ++
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVIN--------- 89
Query: 207 DECERDTHTCQQICSNTEGSYECSCEDGYEKRG-DACVDINECHEE-GVCPSPGRCVNLL 380
D H + C GYE D+CVD++EC + C C NL
Sbjct: 90 -----DLHGEGPPPPVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLP 144
Query: 381 GSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVRSPS 548
GS++C CP GYR G CVD DEC CQ C N G +RC C G P+
Sbjct: 145 GSYQCTCPDGYR--KIGPECVDIDECRYR-YCQHRCVNLPGSFRCQCEPGFQLGPN 197
>BC010456-1|AAH10456.1| 443|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 2 protein.
Length = 443
Score = 130 bits (313), Expect = 4e-30
Identities = 69/170 (40%), Positives = 83/170 (48%), Gaps = 6/170 (3%)
Frame = +3
Query: 39 CGPGYRPAGR-GVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C PGY P + DECA C Q CHN GSY C C GY + G C D+D
Sbjct: 109 CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYR--KIGPECVDID 166
Query: 210 ECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPSPGRCVNLLG 383
EC CQ C N GS+ C CE G++ +CVD+NEC C RC N G
Sbjct: 167 ECR--YRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQ--RCFNSYG 222
Query: 384 SFRCVCPRGYRLDAEGARCVDRDECAQTG-RCQAPCRNYAGGYRCDCPVG 530
+F C C +GY L +G C D DEC+ + CQ C N G + C CP G
Sbjct: 223 TFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQG 272
Score = 127 bits (307), Expect = 2e-29
Identities = 70/174 (40%), Positives = 93/174 (53%), Gaps = 6/174 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N GS++C C GYR G DEC R C C N GS+ C C G++L +
Sbjct: 142 NLPGSYQCTCPDGYRKIGPECVDIDECRYRY--CQHRCVNLPGSFRCQCEPGFQLGPNNR 199
Query: 192 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINEC-HEEGVCPSPG 362
+C DV+EC+ C+Q C N+ G++ C C GYE + G +C DI+EC + +C
Sbjct: 200 SCVDVNECDMGA-PCEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQY-- 256
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQ--APCRNYAGGYRC 515
RCVN G F C CP+GY+L A C D DEC + +C C N+ GGYRC
Sbjct: 257 RCVNEPGRFSCHCPQGYQLLAT-RLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 118 bits (284), Expect = 1e-26
Identities = 65/169 (38%), Positives = 83/169 (49%), Gaps = 5/169 (2%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
R VN GSFRC C PG++ P R +EC + P C+Q C N+ G++ C C GYEL
Sbjct: 176 RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAP-CEQRCFNSYGTFLCRCHQGYEL 234
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD-ACVDINECHEEGV-- 347
DG +C D+DEC ++ CQ C N G + C C GY+ C DI+EC E G
Sbjct: 235 HRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDEC-ESGAHQ 293
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRN 494
C CVN G +RCV + RCV+ RC P N
Sbjct: 294 CSEAQTCVNFHGGYRCV---------DTNRCVEPYIQVSENRCLCPASN 333
Score = 75.4 bits (177), Expect = 1e-13
Identities = 56/176 (31%), Positives = 72/176 (40%), Gaps = 4/176 (2%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDV 206
C G + P + R +EC P C + C N G Y CL R+ ++
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVIN--------- 89
Query: 207 DECERDTHTCQQICSNTEGSYECSCEDGYEKRG-DACVDINECHEE-GVCPSPGRCVNLL 380
D H + C GYE D+CVD++EC + C C NL
Sbjct: 90 -----DLHGEGPPPPVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLP 144
Query: 381 GSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVRSPS 548
GS++C CP GYR G CVD DEC CQ C N G +RC C G P+
Sbjct: 145 GSYQCTCPDGYR--KIGPECVDIDECRYR-YCQHRCVNLPGSFRCQCEPGFQLGPN 197
>AY358899-1|AAQ89258.1| 443|Homo sapiens EFEMP2 protein.
Length = 443
Score = 130 bits (313), Expect = 4e-30
Identities = 69/170 (40%), Positives = 83/170 (48%), Gaps = 6/170 (3%)
Frame = +3
Query: 39 CGPGYRPAGR-GVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C PGY P + DECA C Q CHN GSY C C GY + G C D+D
Sbjct: 109 CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYR--KIGPECVDID 166
Query: 210 ECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPSPGRCVNLLG 383
EC CQ C N GS+ C CE G++ +CVD+NEC C RC N G
Sbjct: 167 ECR--YRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQ--RCFNSYG 222
Query: 384 SFRCVCPRGYRLDAEGARCVDRDECAQTG-RCQAPCRNYAGGYRCDCPVG 530
+F C C +GY L +G C D DEC+ + CQ C N G + C CP G
Sbjct: 223 TFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQG 272
Score = 127 bits (307), Expect = 2e-29
Identities = 70/174 (40%), Positives = 93/174 (53%), Gaps = 6/174 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N GS++C C GYR G DEC R C C N GS+ C C G++L +
Sbjct: 142 NLPGSYQCTCPDGYRKIGPECVDIDECRYRY--CQHRCVNLPGSFRCQCEPGFQLGPNNR 199
Query: 192 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINEC-HEEGVCPSPG 362
+C DV+EC+ C+Q C N+ G++ C C GYE + G +C DI+EC + +C
Sbjct: 200 SCVDVNECDMGA-PCEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQY-- 256
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQ--APCRNYAGGYRC 515
RCVN G F C CP+GY+L A C D DEC + +C C N+ GGYRC
Sbjct: 257 RCVNEPGRFSCHCPQGYQLLAT-RLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 118 bits (284), Expect = 1e-26
Identities = 65/169 (38%), Positives = 83/169 (49%), Gaps = 5/169 (2%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
R VN GSFRC C PG++ P R +EC + P C+Q C N+ G++ C C GYEL
Sbjct: 176 RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAP-CEQRCFNSYGTFLCRCHQGYEL 234
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD-ACVDINECHEEGV-- 347
DG +C D+DEC ++ CQ C N G + C C GY+ C DI+EC E G
Sbjct: 235 HRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDEC-ESGAHQ 293
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRN 494
C CVN G +RCV + RCV+ RC P N
Sbjct: 294 CSEAQTCVNFHGGYRCV---------DTNRCVEPYIQVSENRCLCPASN 333
Score = 75.4 bits (177), Expect = 1e-13
Identities = 56/176 (31%), Positives = 72/176 (40%), Gaps = 4/176 (2%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDV 206
C G + P + R +EC P C + C N G Y CL R+ ++
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVIN--------- 89
Query: 207 DECERDTHTCQQICSNTEGSYECSCEDGYEKRG-DACVDINECHEE-GVCPSPGRCVNLL 380
D H + C GYE D+CVD++EC + C C NL
Sbjct: 90 -----DLHGEGPPPPVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLP 144
Query: 381 GSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVRSPS 548
GS++C CP GYR G CVD DEC CQ C N G +RC C G P+
Sbjct: 145 GSYQCTCPDGYR--KIGPECVDIDECRYR-YCQHRCVNLPGSFRCQCEPGFQLGPN 197
>AJ132819-1|CAA10791.2| 443|Homo sapiens fibulin-4 protein.
Length = 443
Score = 130 bits (313), Expect = 4e-30
Identities = 69/170 (40%), Positives = 83/170 (48%), Gaps = 6/170 (3%)
Frame = +3
Query: 39 CGPGYRPAGR-GVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C PGY P + DECA C Q CHN GSY C C GY + G C D+D
Sbjct: 109 CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYR--KIGPECVDID 166
Query: 210 ECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPSPGRCVNLLG 383
EC CQ C N GS+ C CE G++ +CVD+NEC C RC N G
Sbjct: 167 ECR--YRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQ--RCFNSYG 222
Query: 384 SFRCVCPRGYRLDAEGARCVDRDECAQTG-RCQAPCRNYAGGYRCDCPVG 530
+F C C +GY L +G C D DEC+ + CQ C N G + C CP G
Sbjct: 223 TFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQG 272
Score = 127 bits (307), Expect = 2e-29
Identities = 70/174 (40%), Positives = 93/174 (53%), Gaps = 6/174 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N GS++C C GYR G DEC R C C N GS+ C C G++L +
Sbjct: 142 NLPGSYQCTCPDGYRKIGPECVDIDECRYRY--CQHRCVNLPGSFRCQCEPGFQLGPNNR 199
Query: 192 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINEC-HEEGVCPSPG 362
+C DV+EC+ C+Q C N+ G++ C C GYE + G +C DI+EC + +C
Sbjct: 200 SCVDVNECDMGA-PCEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQY-- 256
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQ--APCRNYAGGYRC 515
RCVN G F C CP+GY+L A C D DEC + +C C N+ GGYRC
Sbjct: 257 RCVNEPGRFSCHCPQGYQLLAT-RLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 118 bits (284), Expect = 1e-26
Identities = 65/169 (38%), Positives = 83/169 (49%), Gaps = 5/169 (2%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
R VN GSFRC C PG++ P R +EC + P C+Q C N+ G++ C C GYEL
Sbjct: 176 RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAP-CEQRCFNSYGTFLCRCHQGYEL 234
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD-ACVDINECHEEGV-- 347
DG +C D+DEC ++ CQ C N G + C C GY+ C DI+EC E G
Sbjct: 235 HRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDEC-ESGAHQ 293
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRN 494
C CVN G +RCV + RCV+ RC P N
Sbjct: 294 CSEAQTCVNFHGGYRCV---------DTNRCVEPYIQVSENRCLCPASN 333
Score = 75.4 bits (177), Expect = 1e-13
Identities = 56/176 (31%), Positives = 72/176 (40%), Gaps = 4/176 (2%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDV 206
C G + P + R +EC P C + C N G Y CL R+ ++
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVIN--------- 89
Query: 207 DECERDTHTCQQICSNTEGSYECSCEDGYEKRG-DACVDINECHEE-GVCPSPGRCVNLL 380
D H + C GYE D+CVD++EC + C C NL
Sbjct: 90 -----DLHGEGPPPPVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLP 144
Query: 381 GSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVRSPS 548
GS++C CP GYR G CVD DEC CQ C N G +RC C G P+
Sbjct: 145 GSYQCTCPDGYR--KIGPECVDIDECRYR-YCQHRCVNLPGSFRCQCEPGFQLGPN 197
>AF109121-1|AAF65188.1| 443|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 2 protein.
Length = 443
Score = 130 bits (313), Expect = 4e-30
Identities = 69/170 (40%), Positives = 83/170 (48%), Gaps = 6/170 (3%)
Frame = +3
Query: 39 CGPGYRPAGR-GVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C PGY P + DECA C Q CHN GSY C C GY + G C D+D
Sbjct: 109 CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYR--KIGPECVDID 166
Query: 210 ECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPSPGRCVNLLG 383
EC CQ C N GS+ C CE G++ +CVD+NEC C RC N G
Sbjct: 167 ECR--YRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQ--RCFNSYG 222
Query: 384 SFRCVCPRGYRLDAEGARCVDRDECAQTG-RCQAPCRNYAGGYRCDCPVG 530
+F C C +GY L +G C D DEC+ + CQ C N G + C CP G
Sbjct: 223 TFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQG 272
Score = 127 bits (307), Expect = 2e-29
Identities = 70/174 (40%), Positives = 93/174 (53%), Gaps = 6/174 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N GS++C C GYR G DEC R C C N GS+ C C G++L +
Sbjct: 142 NLPGSYQCTCPDGYRKIGPECVDIDECRYRY--CQHRCVNLPGSFRCQCEPGFQLGPNNR 199
Query: 192 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINEC-HEEGVCPSPG 362
+C DV+EC+ C+Q C N+ G++ C C GYE + G +C DI+EC + +C
Sbjct: 200 SCVDVNECDMGA-PCEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQY-- 256
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQ--APCRNYAGGYRC 515
RCVN G F C CP+GY+L A C D DEC + +C C N+ GGYRC
Sbjct: 257 RCVNEPGRFSCHCPQGYQLLAT-RLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 118 bits (284), Expect = 1e-26
Identities = 65/169 (38%), Positives = 83/169 (49%), Gaps = 5/169 (2%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
R VN GSFRC C PG++ P R +EC + P C+Q C N+ G++ C C GYEL
Sbjct: 176 RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAP-CEQRCFNSYGTFLCRCHQGYEL 234
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD-ACVDINECHEEGV-- 347
DG +C D+DEC ++ CQ C N G + C C GY+ C DI+EC E G
Sbjct: 235 HRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDEC-ESGAHQ 293
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRN 494
C CVN G +RCV + RCV+ RC P N
Sbjct: 294 CSEAQTCVNFHGGYRCV---------DTNRCVEPYIQVSENRCLCPASN 333
Score = 75.4 bits (177), Expect = 1e-13
Identities = 56/176 (31%), Positives = 72/176 (40%), Gaps = 4/176 (2%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDV 206
C G + P + R +EC P C + C N G Y CL R+ ++
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVIN--------- 89
Query: 207 DECERDTHTCQQICSNTEGSYECSCEDGYEKRG-DACVDINECHEE-GVCPSPGRCVNLL 380
D H + C GYE D+CVD++EC + C C NL
Sbjct: 90 -----DLHGEGPPPPVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLP 144
Query: 381 GSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVRSPS 548
GS++C CP GYR G CVD DEC CQ C N G +RC C G P+
Sbjct: 145 GSYQCTCPDGYR--KIGPECVDIDECRYR-YCQHRCVNLPGSFRCQCEPGFQLGPN 197
>AB030655-1|BAA92880.1| 443|Homo sapiens mutant p53 binding protein
1 (MBP1) protein.
Length = 443
Score = 130 bits (313), Expect = 4e-30
Identities = 69/170 (40%), Positives = 83/170 (48%), Gaps = 6/170 (3%)
Frame = +3
Query: 39 CGPGYRPAGR-GVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C PGY P + DECA C Q CHN GSY C C GY + G C D+D
Sbjct: 109 CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYR--KIGPECVDID 166
Query: 210 ECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPSPGRCVNLLG 383
EC CQ C N GS+ C CE G++ +CVD+NEC C RC N G
Sbjct: 167 ECR--YRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQ--RCFNSYG 222
Query: 384 SFRCVCPRGYRLDAEGARCVDRDECAQTG-RCQAPCRNYAGGYRCDCPVG 530
+F C C +GY L +G C D DEC+ + CQ C N G + C CP G
Sbjct: 223 TFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQG 272
Score = 127 bits (307), Expect = 2e-29
Identities = 70/174 (40%), Positives = 93/174 (53%), Gaps = 6/174 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N GS++C C GYR G DEC R C C N GS+ C C G++L +
Sbjct: 142 NLPGSYQCTCPDGYRKIGPECVDIDECRYRY--CQHRCVNLPGSFRCQCEPGFQLGPNNR 199
Query: 192 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINEC-HEEGVCPSPG 362
+C DV+EC+ C+Q C N+ G++ C C GYE + G +C DI+EC + +C
Sbjct: 200 SCVDVNECDMGA-PCEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQY-- 256
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQ--APCRNYAGGYRC 515
RCVN G F C CP+GY+L A C D DEC + +C C N+ GGYRC
Sbjct: 257 RCVNEPGRFSCHCPQGYQLLAT-RLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 118 bits (284), Expect = 1e-26
Identities = 65/169 (38%), Positives = 83/169 (49%), Gaps = 5/169 (2%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
R VN GSFRC C PG++ P R +EC + P C+Q C N+ G++ C C GYEL
Sbjct: 176 RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAP-CEQRCFNSYGTFLCRCHQGYEL 234
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD-ACVDINECHEEGV-- 347
DG +C D+DEC ++ CQ C N G + C C GY+ C DI+EC E G
Sbjct: 235 HRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDEC-ESGAHQ 293
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRN 494
C CVN G +RCV + RCV+ RC P N
Sbjct: 294 CSEAQTCVNFHGGYRCV---------DTNRCVEPYIQVSENRCLCPASN 333
Score = 75.4 bits (177), Expect = 1e-13
Identities = 56/176 (31%), Positives = 72/176 (40%), Gaps = 4/176 (2%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDV 206
C G + P + R +EC P C + C N G Y CL R+ ++
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVIN--------- 89
Query: 207 DECERDTHTCQQICSNTEGSYECSCEDGYEKRG-DACVDINECHEE-GVCPSPGRCVNLL 380
D H + C GYE D+CVD++EC + C C NL
Sbjct: 90 -----DLHGEGPPPPVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLP 144
Query: 381 GSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVRSPS 548
GS++C CP GYR G CVD DEC CQ C N G +RC C G P+
Sbjct: 145 GSYQCTCPDGYR--KIGPECVDIDECRYR-YCQHRCVNLPGSFRCQCEPGFQLGPN 197
>AF124486-1|AAG45245.1| 443|Homo sapiens fibulin-like extracellular
matrix protein protein.
Length = 443
Score = 128 bits (308), Expect = 2e-29
Identities = 70/174 (40%), Positives = 93/174 (53%), Gaps = 6/174 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N GS++C C GYR G DEC R C C N GS+ C C G++L +
Sbjct: 142 NLSGSYQCTCPDGYRKIGPECVDIDECRYRY--CQHRCVNLPGSFRCQCEPGFQLGPNNR 199
Query: 192 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINEC-HEEGVCPSPG 362
+C DV+EC+ C+Q C N+ G++ C C GYE + G +C DI+EC + +C
Sbjct: 200 SCVDVNECDMGA-PCEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQY-- 256
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQ--APCRNYAGGYRC 515
RCVN G F C CP+GY+L A C D DEC + +C C N+ GGYRC
Sbjct: 257 RCVNEPGRFSCHCPQGYQLLAT-RLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 127 bits (307), Expect = 2e-29
Identities = 68/170 (40%), Positives = 83/170 (48%), Gaps = 6/170 (3%)
Frame = +3
Query: 39 CGPGYRPAGR-GVRGRDECA--VRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
C PGY P + DECA + Q CHN GSY C C GY + G C D+D
Sbjct: 109 CPPGYEPDDQDSCVDVDECAQALHDRRPSQDCHNLSGSYQCTCPDGYR--KIGPECVDID 166
Query: 210 ECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPSPGRCVNLLG 383
EC CQ C N GS+ C CE G++ +CVD+NEC C RC N G
Sbjct: 167 ECR--YRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQ--RCFNSYG 222
Query: 384 SFRCVCPRGYRLDAEGARCVDRDECAQTG-RCQAPCRNYAGGYRCDCPVG 530
+F C C +GY L +G C D DEC+ + CQ C N G + C CP G
Sbjct: 223 TFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQG 272
Score = 118 bits (284), Expect = 1e-26
Identities = 65/169 (38%), Positives = 83/169 (49%), Gaps = 5/169 (2%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
R VN GSFRC C PG++ P R +EC + P C+Q C N+ G++ C C GYEL
Sbjct: 176 RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAP-CEQRCFNSYGTFLCRCHQGYEL 234
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD-ACVDINECHEEGV-- 347
DG +C D+DEC ++ CQ C N G + C C GY+ C DI+EC E G
Sbjct: 235 HRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDEC-ESGAHQ 293
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRN 494
C CVN G +RCV + RCV+ RC P N
Sbjct: 294 CSEAQTCVNFHGGYRCV---------DTNRCVEPYIQVSENRCLCPASN 333
Score = 75.4 bits (177), Expect = 1e-13
Identities = 56/176 (31%), Positives = 73/176 (41%), Gaps = 4/176 (2%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDV 206
C G + P + R +EC P C + C N G Y CL R+ ++
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVIN--------- 89
Query: 207 DECERDTHTCQQICSNTEGSYECSCEDGYEKRG-DACVDINECHEEGVCPSPGR-CVNLL 380
D H + C GYE D+CVD++EC + P + C NL
Sbjct: 90 -----DLHGEGPPPPVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDRRPSQDCHNLS 144
Query: 381 GSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVRSPS 548
GS++C CP GYR G CVD DEC CQ C N G +RC C G P+
Sbjct: 145 GSYQCTCPDGYR--KIGPECVDIDECRYR-YCQHRCVNLPGSFRCQCEPGFQLGPN 197
>AF093119-1|AAC62108.1| 439|Homo sapiens UPH1 protein.
Length = 439
Score = 127 bits (306), Expect = 3e-29
Identities = 71/175 (40%), Positives = 94/175 (53%), Gaps = 7/175 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N GS++C C GYR G DEC R C C N GS+ C C G++L +
Sbjct: 138 NLPGSYQCTCPDGYRKIGPECVDIDECRYRY--CQHRCVNLPGSFRCQCEPGFQLGPNNR 195
Query: 192 NCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINEC-HEEGVCPSPG 362
+C DV+EC+ C+Q C N+ G++ C C GYE + G +C DI+EC + +C
Sbjct: 196 SCVDVNECDMGA-PCEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQY-- 252
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ----APCRNYAGGYRC 515
RCVN G F C CP+GY+L A C D DEC ++G Q C N+ GGYRC
Sbjct: 253 RCVNEPGRFSCHCPQGYQLLAT-RLCQDIDEC-ESGAHQWSEAQTCVNFHGGYRC 305
Score = 124 bits (300), Expect = 2e-28
Identities = 64/154 (41%), Positives = 77/154 (50%), Gaps = 5/154 (3%)
Frame = +3
Query: 84 DECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNT 257
DECA C Q CHN GSY C C GY + G C D+DEC CQ C N
Sbjct: 121 DECAQALHDCRPSQDCHNLPGSYQCTCPDGYR--KIGPECVDIDECR--YRYCQHRCVNL 176
Query: 258 EGSYECSCEDGYE--KRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEG 431
GS+ C CE G++ +CVD+NEC C RC N G+F C C +GY L +G
Sbjct: 177 PGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQ--RCFNSYGTFLCRCHQGYELHRDG 234
Query: 432 ARCVDRDECAQTG-RCQAPCRNYAGGYRCDCPVG 530
C D DEC+ + CQ C N G + C CP G
Sbjct: 235 FSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQG 268
Score = 117 bits (282), Expect = 2e-26
Identities = 59/125 (47%), Positives = 70/125 (56%), Gaps = 2/125 (1%)
Frame = +3
Query: 162 TGYELDEDGANCRDVDECERDTHTCQ--QICSNTEGSYECSCEDGYEKRGDACVDINECH 335
TGYE D D +C DVDEC + H C+ Q C N GSY+C+C DGY K G CVDI+EC
Sbjct: 107 TGYEPD-DQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECR 165
Query: 336 EEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRC 515
C RCVNL GSFRC C G++L CVD +EC C+ C N G + C
Sbjct: 166 YR-YCQH--RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTFLC 222
Query: 516 DCPVG 530
C G
Sbjct: 223 RCHQG 227
Score = 114 bits (274), Expect = 2e-25
Identities = 63/168 (37%), Positives = 82/168 (48%), Gaps = 4/168 (2%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL 176
R VN GSFRC C PG++ P R +EC + P C+Q C N+ G++ C C GYEL
Sbjct: 172 RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAP-CEQRCFNSYGTFLCRCHQGYEL 230
Query: 177 DEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD-ACVDINECHEEGVCP 353
DG +C D+DEC ++ CQ C N G + C C GY+ C DI+EC
Sbjct: 231 HRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQW 290
Query: 354 SPGR-CVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRN 494
S + CVN G +RCV + RCV+ RC P N
Sbjct: 291 SEAQTCVNFHGGYRCV---------DTNRCVEPYIQVSENRCLCPASN 329
Score = 70.1 bits (164), Expect = 5e-12
Identities = 38/89 (42%), Positives = 46/89 (51%), Gaps = 2/89 (2%)
Frame = +3
Query: 288 GYEKRG-DACVDINECHEE-GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA 461
GYE D+CVD++EC + C C NL GS++C CP GYR G CVD DEC
Sbjct: 108 GYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYR--KIGPECVDIDECR 165
Query: 462 QTGRCQAPCRNYAGGYRCDCPVGTVRSPS 548
CQ C N G +RC C G P+
Sbjct: 166 YR-YCQHRCVNLPGSFRCQCEPGFQLGPN 193
Score = 57.2 bits (132), Expect = 4e-08
Identities = 49/130 (37%), Positives = 55/130 (42%), Gaps = 5/130 (3%)
Frame = +3
Query: 156 CRTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGDACVDINE 329
C GY ANCRDV+EC C + C N G Y C R A IN+
Sbjct: 39 CTDGYT---QTANCRDVNECLTIPEACKGEMKCINHYGGYLCL------PRSAAV--IND 87
Query: 330 CHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQT---GRCQAPCRNYA 500
H EG P P VN P GY D + + CVD DECAQ R C N
Sbjct: 88 LHGEGP-PPPVPPVNTQ-----PLPTGYEPDDQDS-CVDVDECAQALHDCRPSQDCHNLP 140
Query: 501 GGYRCDCPVG 530
G Y+C CP G
Sbjct: 141 GSYQCTCPDG 150
>L13720-1|AAA58494.1| 678|Homo sapiens growth-arrest-specific
protein protein.
Length = 678
Score = 124 bits (299), Expect = 2e-28
Identities = 62/153 (40%), Positives = 82/153 (53%), Gaps = 7/153 (4%)
Frame = +3
Query: 84 DECAVRPPPCD----QLCHNTDGSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQIC 248
D+C P PCD Q C + G++ CLC+ G+ G C +DV+EC ++ C QIC
Sbjct: 118 DQCT--PNPCDRKGTQACQDLMGNFFCLCKAGW----GGRLCDKDVNECSQENGGCLQIC 171
Query: 249 SNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLD 422
N GS+ CSC G+E D C DI+EC + C RC NL GS+ C+C G+
Sbjct: 172 HNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEAC-GEARCKNLPGSYSCLCDEGFAYS 230
Query: 423 AEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
++ C D DEC Q GRC+ C N G Y C C
Sbjct: 231 SQEKACRDVDECLQ-GRCEQVCVNSPGSYTCHC 262
Score = 107 bits (258), Expect = 2e-23
Identities = 63/180 (35%), Positives = 90/180 (50%), Gaps = 6/180 (3%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGV-RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
+G+F C+C G+ GR + +EC+ C Q+CHN GS+ C C +G+EL DG
Sbjct: 137 MGNFFCLCKAGW--GGRLCDKDVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRT 194
Query: 195 CRDVDECERDTHTCQQI-CSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCPSPGR 365
C+D+DEC D+ C + C N GSY C C++G Y + AC D++EC +G C
Sbjct: 195 CQDIDEC-ADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDEC-LQGRCEQV-- 250
Query: 366 CVNLLGSFRCVCP--RGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVR 539
CVN GS+ C C G +L + C D C ++ Y G PV +R
Sbjct: 251 CVNSPGSYTCHCDGRGGLKLSQDMDTCEDILPCVPFSVAKSVKSLYLGRMFSGTPVIRLR 310
Score = 80.2 bits (189), Expect = 4e-15
Identities = 45/113 (39%), Positives = 55/113 (48%), Gaps = 6/113 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
N GSF C C G+ + GR + DECA + C N GSY CLC G+
Sbjct: 173 NKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSSQ 232
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCED-GYEKRG---DACVDINEC 332
CRDVDEC + C+Q+C N+ GSY C C+ G K D C DI C
Sbjct: 233 EKACRDVDECLQG--RCEQVCVNSPGSYTCHCDGRGGLKLSQDMDTCEDILPC 283
Score = 45.2 bits (102), Expect = 2e-04
Identities = 29/85 (34%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
Frame = +3
Query: 306 DACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRD--ECAQ-TGRC 476
D C N C +G C +L+G+F C+C G+ G R D+D EC+Q G C
Sbjct: 118 DQCTP-NPCDRKGT----QACQDLMGNFFCLCKAGW-----GGRLCDKDVNECSQENGGC 167
Query: 477 QAPCRNYAGGYRCDCPVGTVRSPSG 551
C N G + C C G S G
Sbjct: 168 LQICHNKPGSFHCSCHSGFELSSDG 192
>EF631974-1|ABR09277.1| 678|Homo sapiens growth arrest-specific 6
protein.
Length = 678
Score = 124 bits (299), Expect = 2e-28
Identities = 62/153 (40%), Positives = 82/153 (53%), Gaps = 7/153 (4%)
Frame = +3
Query: 84 DECAVRPPPCD----QLCHNTDGSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQIC 248
D+C P PCD Q C + G++ CLC+ G+ G C +DV+EC ++ C QIC
Sbjct: 118 DQCT--PNPCDRKGTQACQDLMGNFFCLCKAGW----GGRLCDKDVNECSQENGGCLQIC 171
Query: 249 SNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLD 422
N GS+ CSC G+E D C DI+EC + C RC NL GS+ C+C G+
Sbjct: 172 HNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEAC-GEARCKNLPGSYSCLCDEGFAYS 230
Query: 423 AEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
++ C D DEC Q GRC+ C N G Y C C
Sbjct: 231 SQEKACRDVDECLQ-GRCEQVCVNSPGSYTCHC 262
Score = 107 bits (258), Expect = 2e-23
Identities = 63/180 (35%), Positives = 90/180 (50%), Gaps = 6/180 (3%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGV-RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
+G+F C+C G+ GR + +EC+ C Q+CHN GS+ C C +G+EL DG
Sbjct: 137 MGNFFCLCKAGW--GGRLCDKDVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRT 194
Query: 195 CRDVDECERDTHTCQQI-CSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCPSPGR 365
C+D+DEC D+ C + C N GSY C C++G Y + AC D++EC +G C
Sbjct: 195 CQDIDEC-ADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDEC-LQGRCEQV-- 250
Query: 366 CVNLLGSFRCVCP--RGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVR 539
CVN GS+ C C G +L + C D C ++ Y G PV +R
Sbjct: 251 CVNSPGSYTCHCDGRGGLKLSQDMDTCEDILPCVPFSVAKSVKSLYLGRMFSGTPVIRLR 310
Score = 80.2 bits (189), Expect = 4e-15
Identities = 45/113 (39%), Positives = 55/113 (48%), Gaps = 6/113 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
N GSF C C G+ + GR + DECA + C N GSY CLC G+
Sbjct: 173 NKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSSQ 232
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCED-GYEKRG---DACVDINEC 332
CRDVDEC + C+Q+C N+ GSY C C+ G K D C DI C
Sbjct: 233 EKACRDVDECLQG--RCEQVCVNSPGSYTCHCDGRGGLKLSQDMDTCEDILPC 283
Score = 45.2 bits (102), Expect = 2e-04
Identities = 29/85 (34%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
Frame = +3
Query: 306 DACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRD--ECAQ-TGRC 476
D C N C +G C +L+G+F C+C G+ G R D+D EC+Q G C
Sbjct: 118 DQCTP-NPCDRKGT----QACQDLMGNFFCLCKAGW-----GGRLCDKDVNECSQENGGC 167
Query: 477 QAPCRNYAGGYRCDCPVGTVRSPSG 551
C N G + C C G S G
Sbjct: 168 LQICHNKPGSFHCSCHSGFELSSDG 192
>BX072579-3|CAH71174.1| 678|Homo sapiens growth arrest-specific 6
protein.
Length = 678
Score = 124 bits (299), Expect = 2e-28
Identities = 62/153 (40%), Positives = 82/153 (53%), Gaps = 7/153 (4%)
Frame = +3
Query: 84 DECAVRPPPCD----QLCHNTDGSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQIC 248
D+C P PCD Q C + G++ CLC+ G+ G C +DV+EC ++ C QIC
Sbjct: 118 DQCT--PNPCDRKGTQACQDLMGNFFCLCKAGW----GGRLCDKDVNECSQENGGCLQIC 171
Query: 249 SNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLD 422
N GS+ CSC G+E D C DI+EC + C RC NL GS+ C+C G+
Sbjct: 172 HNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEAC-GEARCKNLPGSYSCLCDEGFAYS 230
Query: 423 AEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
++ C D DEC Q GRC+ C N G Y C C
Sbjct: 231 SQEKACRDVDECLQ-GRCEQVCVNSPGSYTCHC 262
Score = 107 bits (258), Expect = 2e-23
Identities = 63/180 (35%), Positives = 90/180 (50%), Gaps = 6/180 (3%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGV-RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
+G+F C+C G+ GR + +EC+ C Q+CHN GS+ C C +G+EL DG
Sbjct: 137 MGNFFCLCKAGW--GGRLCDKDVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRT 194
Query: 195 CRDVDECERDTHTCQQI-CSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCPSPGR 365
C+D+DEC D+ C + C N GSY C C++G Y + AC D++EC +G C
Sbjct: 195 CQDIDEC-ADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDEC-LQGRCEQV-- 250
Query: 366 CVNLLGSFRCVCP--RGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVR 539
CVN GS+ C C G +L + C D C ++ Y G PV +R
Sbjct: 251 CVNSPGSYTCHCDGRGGLKLSQDMDTCEDILPCVPFSVAKSVKSLYLGRMFSGTPVIRLR 310
Score = 80.2 bits (189), Expect = 4e-15
Identities = 45/113 (39%), Positives = 55/113 (48%), Gaps = 6/113 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
N GSF C C G+ + GR + DECA + C N GSY CLC G+
Sbjct: 173 NKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSSQ 232
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCED-GYEKRG---DACVDINEC 332
CRDVDEC + C+Q+C N+ GSY C C+ G K D C DI C
Sbjct: 233 EKACRDVDECLQG--RCEQVCVNSPGSYTCHCDGRGGLKLSQDMDTCEDILPC 283
Score = 45.2 bits (102), Expect = 2e-04
Identities = 29/85 (34%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
Frame = +3
Query: 306 DACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRD--ECAQ-TGRC 476
D C N C +G C +L+G+F C+C G+ G R D+D EC+Q G C
Sbjct: 118 DQCTP-NPCDRKGT----QACQDLMGNFFCLCKAGW-----GGRLCDKDVNECSQENGGC 167
Query: 477 QAPCRNYAGGYRCDCPVGTVRSPSG 551
C N G + C C G S G
Sbjct: 168 LQICHNKPGSFHCSCHSGFELSSDG 192
>BC038984-1|AAH38984.1| 678|Homo sapiens growth arrest-specific 6
protein.
Length = 678
Score = 124 bits (299), Expect = 2e-28
Identities = 62/153 (40%), Positives = 82/153 (53%), Gaps = 7/153 (4%)
Frame = +3
Query: 84 DECAVRPPPCD----QLCHNTDGSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQIC 248
D+C P PCD Q C + G++ CLC+ G+ G C +DV+EC ++ C QIC
Sbjct: 118 DQCT--PNPCDRKGTQACQDLMGNFFCLCKAGW----GGRLCDKDVNECSQENGGCLQIC 171
Query: 249 SNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLD 422
N GS+ CSC G+E D C DI+EC + C RC NL GS+ C+C G+
Sbjct: 172 HNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEAC-GEARCKNLPGSYSCLCDEGFAYS 230
Query: 423 AEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
++ C D DEC Q GRC+ C N G Y C C
Sbjct: 231 SQEKACRDVDECLQ-GRCEQVCVNSPGSYTCHC 262
Score = 107 bits (258), Expect = 2e-23
Identities = 63/180 (35%), Positives = 90/180 (50%), Gaps = 6/180 (3%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGV-RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
+G+F C+C G+ GR + +EC+ C Q+CHN GS+ C C +G+EL DG
Sbjct: 137 MGNFFCLCKAGW--GGRLCDKDVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRT 194
Query: 195 CRDVDECERDTHTCQQI-CSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCPSPGR 365
C+D+DEC D+ C + C N GSY C C++G Y + AC D++EC +G C
Sbjct: 195 CQDIDEC-ADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDEC-LQGRCEQV-- 250
Query: 366 CVNLLGSFRCVCP--RGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVR 539
CVN GS+ C C G +L + C D C ++ Y G PV +R
Sbjct: 251 CVNSPGSYTCHCDGRGGLKLSQDMDTCEDILPCVPFSVAKSVKSLYLGRMFSGTPVIRLR 310
Score = 80.2 bits (189), Expect = 4e-15
Identities = 45/113 (39%), Positives = 55/113 (48%), Gaps = 6/113 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
N GSF C C G+ + GR + DECA + C N GSY CLC G+
Sbjct: 173 NKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSSQ 232
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCED-GYEKRG---DACVDINEC 332
CRDVDEC + C+Q+C N+ GSY C C+ G K D C DI C
Sbjct: 233 EKACRDVDECLQG--RCEQVCVNSPGSYTCHCDGRGGLKLSQDMDTCEDILPC 283
Score = 45.2 bits (102), Expect = 2e-04
Identities = 29/85 (34%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
Frame = +3
Query: 306 DACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRD--ECAQ-TGRC 476
D C N C +G C +L+G+F C+C G+ G R D+D EC+Q G C
Sbjct: 118 DQCTP-NPCDRKGT----QACQDLMGNFFCLCKAGW-----GGRLCDKDVNECSQENGGC 167
Query: 477 QAPCRNYAGGYRCDCPVGTVRSPSG 551
C N G + C C G S G
Sbjct: 168 LQICHNKPGSFHCSCHSGFELSSDG 192
>AY256843-1|AAO84057.1| 678|Homo sapiens growth arrested-specific 6
protein.
Length = 678
Score = 124 bits (299), Expect = 2e-28
Identities = 62/153 (40%), Positives = 82/153 (53%), Gaps = 7/153 (4%)
Frame = +3
Query: 84 DECAVRPPPCD----QLCHNTDGSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQIC 248
D+C P PCD Q C + G++ CLC+ G+ G C +DV+EC ++ C QIC
Sbjct: 118 DQCT--PNPCDRKGTQACQDLMGNFFCLCKAGW----GGRLCDKDVNECSQENGGCLQIC 171
Query: 249 SNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLD 422
N GS+ CSC G+E D C DI+EC + C RC NL GS+ C+C G+
Sbjct: 172 HNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEAC-GEARCKNLPGSYSCLCDEGFAYS 230
Query: 423 AEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
++ C D DEC Q GRC+ C N G Y C C
Sbjct: 231 SQEKACRDVDECLQ-GRCEQVCVNSPGSYTCHC 262
Score = 107 bits (258), Expect = 2e-23
Identities = 63/180 (35%), Positives = 90/180 (50%), Gaps = 6/180 (3%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGV-RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
+G+F C+C G+ GR + +EC+ C Q+CHN GS+ C C +G+EL DG
Sbjct: 137 MGNFFCLCKAGW--GGRLCDKDVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRT 194
Query: 195 CRDVDECERDTHTCQQI-CSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCPSPGR 365
C+D+DEC D+ C + C N GSY C C++G Y + AC D++EC +G C
Sbjct: 195 CQDIDEC-ADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDEC-LQGRCEQV-- 250
Query: 366 CVNLLGSFRCVCP--RGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVR 539
CVN GS+ C C G +L + C D C ++ Y G PV +R
Sbjct: 251 CVNSPGSYTCHCDGRGGLKLSQDMDTCEDILPCVPFSVAKSVKSLYLGRMFSGTPVIRLR 310
Score = 80.2 bits (189), Expect = 4e-15
Identities = 45/113 (39%), Positives = 55/113 (48%), Gaps = 6/113 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
N GSF C C G+ + GR + DECA + C N GSY CLC G+
Sbjct: 173 NKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSSQ 232
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCED-GYEKRG---DACVDINEC 332
CRDVDEC + C+Q+C N+ GSY C C+ G K D C DI C
Sbjct: 233 EKACRDVDECLQG--RCEQVCVNSPGSYTCHCDGRGGLKLSQDMDTCEDILPC 283
Score = 45.2 bits (102), Expect = 2e-04
Identities = 29/85 (34%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
Frame = +3
Query: 306 DACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRD--ECAQ-TGRC 476
D C N C +G C +L+G+F C+C G+ G R D+D EC+Q G C
Sbjct: 118 DQCTP-NPCDRKGT----QACQDLMGNFFCLCKAGW-----GGRLCDKDVNECSQENGGC 167
Query: 477 QAPCRNYAGGYRCDCPVGTVRSPSG 551
C N G + C C G S G
Sbjct: 168 LQICHNKPGSFHCSCHSGFELSSDG 192
>AK126533-1|BAC86580.1| 624|Homo sapiens protein ( Homo sapiens
cDNA FLJ44569 fis, clone UTERU3009979, highly similar
to Homo sapiens growth arrest-specific 6 (GAS6). ).
Length = 624
Score = 124 bits (299), Expect = 2e-28
Identities = 62/153 (40%), Positives = 82/153 (53%), Gaps = 7/153 (4%)
Frame = +3
Query: 84 DECAVRPPPCD----QLCHNTDGSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQIC 248
D+C P PCD Q C + G++ CLC+ G+ G C +DV+EC ++ C QIC
Sbjct: 64 DQCT--PNPCDRKGTQACQDLMGNFFCLCKAGW----GGRLCDKDVNECSQENGGCLQIC 117
Query: 249 SNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLD 422
N GS+ CSC G+E D C DI+EC + C RC NL GS+ C+C G+
Sbjct: 118 HNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEAC-GEARCKNLPGSYSCLCDEGFAYS 176
Query: 423 AEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
++ C D DEC Q GRC+ C N G Y C C
Sbjct: 177 SQEKACRDVDECLQ-GRCEQVCVNSPGSYTCHC 208
Score = 107 bits (258), Expect = 2e-23
Identities = 63/180 (35%), Positives = 90/180 (50%), Gaps = 6/180 (3%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGV-RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
+G+F C+C G+ GR + +EC+ C Q+CHN GS+ C C +G+EL DG
Sbjct: 83 MGNFFCLCKAGW--GGRLCDKDVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRT 140
Query: 195 CRDVDECERDTHTCQQI-CSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCPSPGR 365
C+D+DEC D+ C + C N GSY C C++G Y + AC D++EC +G C
Sbjct: 141 CQDIDEC-ADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDEC-LQGRCEQV-- 196
Query: 366 CVNLLGSFRCVCP--RGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVR 539
CVN GS+ C C G +L + C D C ++ Y G PV +R
Sbjct: 197 CVNSPGSYTCHCDGRGGLKLSQDMDTCEDILPCVPFSVAKSVKSLYLGRMFSGTPVIRLR 256
Score = 80.2 bits (189), Expect = 4e-15
Identities = 45/113 (39%), Positives = 55/113 (48%), Gaps = 6/113 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
N GSF C C G+ + GR + DECA + C N GSY CLC G+
Sbjct: 119 NKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSSQ 178
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCED-GYEKRG---DACVDINEC 332
CRDVDEC + C+Q+C N+ GSY C C+ G K D C DI C
Sbjct: 179 EKACRDVDECLQG--RCEQVCVNSPGSYTCHCDGRGGLKLSQDMDTCEDILPC 229
Score = 45.2 bits (102), Expect = 2e-04
Identities = 29/85 (34%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
Frame = +3
Query: 306 DACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRD--ECAQ-TGRC 476
D C N C +G C +L+G+F C+C G+ G R D+D EC+Q G C
Sbjct: 64 DQCTP-NPCDRKGT----QACQDLMGNFFCLCKAGW-----GGRLCDKDVNECSQENGGC 113
Query: 477 QAPCRNYAGGYRCDCPVGTVRSPSG 551
C N G + C C G S G
Sbjct: 114 LQICHNKPGSFHCSCHSGFELSSDG 138
>BC111690-1|AAI11691.1| 807|Homo sapiens SCUBE2 protein protein.
Length = 807
Score = 123 bits (296), Expect = 5e-28
Identities = 56/152 (36%), Positives = 76/152 (50%), Gaps = 3/152 (1%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEG 263
+ CAV CD+ C +T C C G+ L DG C+D+DEC+ C C N G
Sbjct: 284 ETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIVG 343
Query: 264 SYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGAR 437
S++C C+ G++ D +C D++EC + C C+N G+F C C RGY L
Sbjct: 344 SFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDH--SCINHPGTFACACNRGYTLYG-FTH 400
Query: 438 CVDRDECA-QTGRCQAPCRNYAGGYRCDCPVG 530
C D +EC+ G CQ C N G Y C C G
Sbjct: 401 CGDTNECSINNGGCQQVCVNTVGSYECQCHPG 432
Score = 109 bits (261), Expect = 8e-24
Identities = 57/148 (38%), Positives = 74/148 (50%), Gaps = 4/148 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
+T C C G+ + G+ + DEC R CD C N GS+DC C+ G++L D
Sbjct: 299 DTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTD 358
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRG-DACVDINECH-EEGVCPSP 359
+C+DVDEC D TC C N G++ C+C GY G C D NEC G C
Sbjct: 359 EKSCQDVDECSLD-RTCDHSCINHPGTFACACNRGYTLYGFTHCGDTNECSINNGGCQQV 417
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCV 443
CVN +GS+ C C GY+L CV
Sbjct: 418 --CVNTVGSYECQCHPGYKLHWNKKDCV 443
Score = 105 bits (252), Expect = 1e-22
Identities = 61/177 (34%), Positives = 78/177 (44%), Gaps = 7/177 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVR-PPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
NT S++C C PGY+ GR DEC C C N G+Y C C G+ L DG
Sbjct: 64 NTPTSYKCSCKPGYQGEGRQCEDIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDG 123
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGR- 365
NC DVDEC + CQ C N GSYEC C++G+ + I+ E C +
Sbjct: 124 HNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHG 183
Query: 366 CVNLL-----GSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
C ++ GS C C G+ L C+ G CQ C + A G C C
Sbjct: 184 CSHICKEAPRGSVACECRPGFELAKNQRDCILTCNHG-NGGCQHSCDDTADGPECSC 239
Score = 102 bits (244), Expect = 1e-21
Identities = 61/174 (35%), Positives = 80/174 (45%), Gaps = 12/174 (6%)
Frame = +3
Query: 45 PGYRPAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECE 218
PG A DECA C D LC NT SY C C+ GY+ +G C D+DEC
Sbjct: 34 PGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCEDIDECG 91
Query: 219 RDTH-TCQQICSNTEGSYECSCEDGY--EKRGDACVDINECHE-EGVCPSPGRCVNLLGS 386
+ + C C N G+Y C+C DG+ G C+D++EC E G C CVN++GS
Sbjct: 92 NELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH--TCVNVMGS 149
Query: 387 FRCVCPRGYRLDAEGARCVDRDE----CAQTGR-CQAPCRNY-AGGYRCDCPVG 530
+ C C G+ L C+ R E C C C+ G C+C G
Sbjct: 150 YECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPG 203
Score = 74.1 bits (174), Expect = 3e-13
Identities = 55/211 (26%), Positives = 81/211 (38%), Gaps = 37/211 (17%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRG---VRGRDE---CAVRPPPCDQLCHNTD-GSYDCLCRTG 167
VN +GS+ C C G+ + + +E C + C +C GS C CR G
Sbjct: 144 VNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPG 203
Query: 168 YELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE---------KRGDACVD 320
+EL ++ +C + C CQ C +T ECSC Y+ +R D ++
Sbjct: 204 FELAKNQRDC--ILTCNHGNGGCQHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLE 261
Query: 321 INECHEEGVCPSPGR--------------------CVNLLGSFRCVCPRGYRLDAEGARC 440
+ E + V R C + C CP G+ L +G C
Sbjct: 262 VTESNTTSVVDGDKRVKRRLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTC 321
Query: 441 VDRDEC-AQTGRCQAPCRNYAGGYRCDCPVG 530
D DEC + G C C+N G + C C G
Sbjct: 322 KDIDECQTRNGGCDHFCKNIVGSFDCGCKKG 352
Score = 54.8 bits (126), Expect = 2e-07
Identities = 30/82 (36%), Positives = 41/82 (50%), Gaps = 4/82 (4%)
Frame = +3
Query: 318 DINECHEEGV--CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ--TGRCQAP 485
D++EC +G+ C + C N S++C C GY+ EG +C D DEC G C
Sbjct: 45 DVDEC-AQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCEDIDECGNELNGGCVHD 101
Query: 486 CRNYAGGYRCDCPVGTVRSPSG 551
C N G YRC C G + + G
Sbjct: 102 CLNIPGNYRCTCFDGFMLAHDG 123
Score = 54.8 bits (126), Expect = 2e-07
Identities = 25/64 (39%), Positives = 35/64 (54%), Gaps = 1/64 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRG-RDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
+N G+F C C GY G G +EC++ C Q+C NT GSY+C C GY+L +
Sbjct: 379 INHPGTFACACNRGYTLYGFTHCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWN 438
Query: 186 GANC 197
+C
Sbjct: 439 KKDC 442
>AK131552-1|BAD18686.1| 682|Homo sapiens protein ( Homo sapiens
cDNA FLJ16792 fis, clone TBAES2007379, moderately
similar to Homo sapiens signal peptide, CUB domain,
EGF-like 2 (SCUBE2). ).
Length = 682
Score = 123 bits (296), Expect = 5e-28
Identities = 56/152 (36%), Positives = 76/152 (50%), Gaps = 3/152 (1%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEG 263
+ CAV CD+ C +T C C G+ L DG C+D+DEC+ C C N G
Sbjct: 284 ETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIVG 343
Query: 264 SYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGAR 437
S++C C+ G++ D +C D++EC + C C+N G+F C C RGY L
Sbjct: 344 SFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDH--SCINHPGTFACACNRGYTLYG-FTH 400
Query: 438 CVDRDECA-QTGRCQAPCRNYAGGYRCDCPVG 530
C D +EC+ G CQ C N G Y C C G
Sbjct: 401 CGDTNECSINNGGCQQVCVNTVGSYECQCHPG 432
Score = 109 bits (261), Expect = 8e-24
Identities = 57/148 (38%), Positives = 74/148 (50%), Gaps = 4/148 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
+T C C G+ + G+ + DEC R CD C N GS+DC C+ G++L D
Sbjct: 299 DTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTD 358
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRG-DACVDINECH-EEGVCPSP 359
+C+DVDEC D TC C N G++ C+C GY G C D NEC G C
Sbjct: 359 EKSCQDVDECSLD-RTCDHSCINHPGTFACACNRGYTLYGFTHCGDTNECSINNGGCQQV 417
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCV 443
CVN +GS+ C C GY+L CV
Sbjct: 418 --CVNTVGSYECQCHPGYKLHWNKKDCV 443
Score = 105 bits (252), Expect = 1e-22
Identities = 61/177 (34%), Positives = 78/177 (44%), Gaps = 7/177 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVR-PPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
NT S++C C PGY+ GR DEC C C N G+Y C C G+ L DG
Sbjct: 64 NTPTSYKCSCKPGYQGEGRQCEDIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDG 123
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGR- 365
NC DVDEC + CQ C N GSYEC C++G+ + I+ E C +
Sbjct: 124 HNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHG 183
Query: 366 CVNLL-----GSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
C ++ GS C C G+ L C+ G CQ C + A G C C
Sbjct: 184 CSHICKEAPRGSVACECRPGFELAKNQRDCILTCNHG-NGGCQHSCDDTADGPECSC 239
Score = 102 bits (244), Expect = 1e-21
Identities = 61/174 (35%), Positives = 80/174 (45%), Gaps = 12/174 (6%)
Frame = +3
Query: 45 PGYRPAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECE 218
PG A DECA C D LC NT SY C C+ GY+ +G C D+DEC
Sbjct: 34 PGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCEDIDECG 91
Query: 219 RDTH-TCQQICSNTEGSYECSCEDGY--EKRGDACVDINECHE-EGVCPSPGRCVNLLGS 386
+ + C C N G+Y C+C DG+ G C+D++EC E G C CVN++GS
Sbjct: 92 NELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH--TCVNVMGS 149
Query: 387 FRCVCPRGYRLDAEGARCVDRDE----CAQTGR-CQAPCRNY-AGGYRCDCPVG 530
+ C C G+ L C+ R E C C C+ G C+C G
Sbjct: 150 YECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPG 203
Score = 74.1 bits (174), Expect = 3e-13
Identities = 55/211 (26%), Positives = 81/211 (38%), Gaps = 37/211 (17%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRG---VRGRDE---CAVRPPPCDQLCHNTD-GSYDCLCRTG 167
VN +GS+ C C G+ + + +E C + C +C GS C CR G
Sbjct: 144 VNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPG 203
Query: 168 YELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE---------KRGDACVD 320
+EL ++ +C + C CQ C +T ECSC Y+ +R D ++
Sbjct: 204 FELAKNQRDC--ILTCNHGNGGCQHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLE 261
Query: 321 INECHEEGVCPSPGR--------------------CVNLLGSFRCVCPRGYRLDAEGARC 440
+ E + V R C + C CP G+ L +G C
Sbjct: 262 VTESNTTSVVDGDKRVKRQLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTC 321
Query: 441 VDRDEC-AQTGRCQAPCRNYAGGYRCDCPVG 530
D DEC + G C C+N G + C C G
Sbjct: 322 KDIDECQTRNGGCDHFCKNIVGSFDCGCKKG 352
Score = 54.8 bits (126), Expect = 2e-07
Identities = 30/82 (36%), Positives = 41/82 (50%), Gaps = 4/82 (4%)
Frame = +3
Query: 318 DINECHEEGV--CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ--TGRCQAP 485
D++EC +G+ C + C N S++C C GY+ EG +C D DEC G C
Sbjct: 45 DVDEC-AQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCEDIDECGNELNGGCVHD 101
Query: 486 CRNYAGGYRCDCPVGTVRSPSG 551
C N G YRC C G + + G
Sbjct: 102 CLNIPGNYRCTCFDGFMLAHDG 123
Score = 54.8 bits (126), Expect = 2e-07
Identities = 25/64 (39%), Positives = 35/64 (54%), Gaps = 1/64 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRG-RDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
+N G+F C C GY G G +EC++ C Q+C NT GSY+C C GY+L +
Sbjct: 379 INHPGTFACACNRGYTLYGFTHCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWN 438
Query: 186 GANC 197
+C
Sbjct: 439 KKDC 442
>AK123039-1|BAC85521.1| 971|Homo sapiens protein ( Homo sapiens
cDNA FLJ41044 fis, clone NT2RP7000466, highly similar
to Mus musculus CUB domain and EGF-like repeat
containing 1 (Cegf1). ).
Length = 971
Score = 123 bits (296), Expect = 5e-28
Identities = 56/152 (36%), Positives = 76/152 (50%), Gaps = 3/152 (1%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEG 263
+ CAV CD+ C +T C C G+ L DG C+D+DEC+ C C N G
Sbjct: 284 ETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIVG 343
Query: 264 SYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGAR 437
S++C C+ G++ D +C D++EC + C C+N G+F C C RGY L
Sbjct: 344 SFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDH--SCINHPGTFACACNRGYTLYG-FTH 400
Query: 438 CVDRDECA-QTGRCQAPCRNYAGGYRCDCPVG 530
C D +EC+ G CQ C N G Y C C G
Sbjct: 401 CGDTNECSINNGGCQQVCVNTVGSYECQCHPG 432
Score = 111 bits (266), Expect = 2e-24
Identities = 63/175 (36%), Positives = 81/175 (46%), Gaps = 7/175 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
+T C C G+ + G+ + DEC R CD C N GS+DC C+ G++L D
Sbjct: 299 DTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTD 358
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRG-DACVDINECH-EEGVCPSP 359
+C+DVDEC D TC C N G++ C+C GY G C D NEC G C
Sbjct: 359 EKSCQDVDECSLD-RTCDHSCINHPGTFACACNRGYTLYGFTHCGDTNECSINNGGCQQV 417
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG---RCQAPCRNYAGGYRC 515
CVN +GS+ C C GY+L CV+ T R C GG C
Sbjct: 418 --CVNTVGSYECQCHPGYKLHWNKKDCVEVKGLLPTSVSPRVSLHCGKSGGGDGC 470
Score = 105 bits (252), Expect = 1e-22
Identities = 61/177 (34%), Positives = 78/177 (44%), Gaps = 7/177 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVR-PPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
NT S++C C PGY+ GR DEC C C N G+Y C C G+ L DG
Sbjct: 64 NTPTSYKCSCKPGYQGEGRQCEDIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDG 123
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGR- 365
NC DVDEC + CQ C N GSYEC C++G+ + I+ E C +
Sbjct: 124 HNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHG 183
Query: 366 CVNLL-----GSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
C ++ GS C C G+ L C+ G CQ C + A G C C
Sbjct: 184 CSHICKEAPRGSVACECRPGFELAKNQRDCILTCNHG-NGGCQHSCDDTADGPECSC 239
Score = 102 bits (244), Expect = 1e-21
Identities = 61/174 (35%), Positives = 80/174 (45%), Gaps = 12/174 (6%)
Frame = +3
Query: 45 PGYRPAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECE 218
PG A DECA C D LC NT SY C C+ GY+ +G C D+DEC
Sbjct: 34 PGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCEDIDECG 91
Query: 219 RDTH-TCQQICSNTEGSYECSCEDGY--EKRGDACVDINECHE-EGVCPSPGRCVNLLGS 386
+ + C C N G+Y C+C DG+ G C+D++EC E G C CVN++GS
Sbjct: 92 NELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH--TCVNVMGS 149
Query: 387 FRCVCPRGYRLDAEGARCVDRDE----CAQTGR-CQAPCRNY-AGGYRCDCPVG 530
+ C C G+ L C+ R E C C C+ G C+C G
Sbjct: 150 YECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPG 203
Score = 74.1 bits (174), Expect = 3e-13
Identities = 55/211 (26%), Positives = 81/211 (38%), Gaps = 37/211 (17%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRG---VRGRDE---CAVRPPPCDQLCHNTD-GSYDCLCRTG 167
VN +GS+ C C G+ + + +E C + C +C GS C CR G
Sbjct: 144 VNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPG 203
Query: 168 YELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE---------KRGDACVD 320
+EL ++ +C + C CQ C +T ECSC Y+ +R D ++
Sbjct: 204 FELAKNQRDC--ILTCNHGNGGCQHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLE 261
Query: 321 INECHEEGVCPSPGR--------------------CVNLLGSFRCVCPRGYRLDAEGARC 440
+ E + V R C + C CP G+ L +G C
Sbjct: 262 VTESNTTSVVDGDKRVKRRLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTC 321
Query: 441 VDRDEC-AQTGRCQAPCRNYAGGYRCDCPVG 530
D DEC + G C C+N G + C C G
Sbjct: 322 KDIDECQTRNGGCDHFCKNIVGSFDCGCKKG 352
Score = 56.0 bits (129), Expect = 8e-08
Identities = 26/67 (38%), Positives = 37/67 (55%), Gaps = 1/67 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRG-RDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
+N G+F C C GY G G +EC++ C Q+C NT GSY+C C GY+L +
Sbjct: 379 INHPGTFACACNRGYTLYGFTHCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWN 438
Query: 186 GANCRDV 206
+C +V
Sbjct: 439 KKDCVEV 445
Score = 54.8 bits (126), Expect = 2e-07
Identities = 30/82 (36%), Positives = 41/82 (50%), Gaps = 4/82 (4%)
Frame = +3
Query: 318 DINECHEEGV--CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ--TGRCQAP 485
D++EC +G+ C + C N S++C C GY+ EG +C D DEC G C
Sbjct: 45 DVDEC-AQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCEDIDECGNELNGGCVHD 101
Query: 486 CRNYAGGYRCDCPVGTVRSPSG 551
C N G YRC C G + + G
Sbjct: 102 CLNIPGNYRCTCFDGFMLAHDG 123
>AJ400877-1|CAB92285.1| 999|Homo sapiens CEGP1 protein protein.
Length = 999
Score = 123 bits (296), Expect = 5e-28
Identities = 56/152 (36%), Positives = 76/152 (50%), Gaps = 3/152 (1%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEG 263
+ CAV CD+ C +T C C G+ L DG C+D+DEC+ C C N G
Sbjct: 284 ETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIVG 343
Query: 264 SYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGAR 437
S++C C+ G++ D +C D++EC + C C+N G+F C C RGY L
Sbjct: 344 SFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDH--SCINHPGTFACACNRGYTLYG-FTH 400
Query: 438 CVDRDECA-QTGRCQAPCRNYAGGYRCDCPVG 530
C D +EC+ G CQ C N G Y C C G
Sbjct: 401 CGDTNECSINNGGCQQVCVNTVGSYECQCHPG 432
Score = 111 bits (266), Expect = 2e-24
Identities = 63/175 (36%), Positives = 81/175 (46%), Gaps = 7/175 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
+T C C G+ + G+ + DEC R CD C N GS+DC C+ G++L D
Sbjct: 299 DTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTD 358
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRG-DACVDINECH-EEGVCPSP 359
+C+DVDEC D TC C N G++ C+C GY G C D NEC G C
Sbjct: 359 EKSCQDVDECSLD-RTCDHSCINHPGTFACACNRGYTLYGFTHCGDTNECSINNGGCQQV 417
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG---RCQAPCRNYAGGYRC 515
CVN +GS+ C C GY+L CV+ T R C GG C
Sbjct: 418 --CVNTVGSYECQCHPGYKLHWNKKDCVEVKGLLPTSVSPRVSLHCGKSGGGDGC 470
Score = 105 bits (252), Expect = 1e-22
Identities = 61/177 (34%), Positives = 78/177 (44%), Gaps = 7/177 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVR-PPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
NT S++C C PGY+ GR DEC C C N G+Y C C G+ L DG
Sbjct: 64 NTPTSYKCSCKPGYQGEGRQCEDIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDG 123
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGR- 365
NC DVDEC + CQ C N GSYEC C++G+ + I+ E C +
Sbjct: 124 HNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHG 183
Query: 366 CVNLL-----GSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
C ++ GS C C G+ L C+ G CQ C + A G C C
Sbjct: 184 CSHICKEAPRGSVACECRPGFELAKNQRDCILTCNHG-NGGCQHSCDDTADGPECSC 239
Score = 102 bits (244), Expect = 1e-21
Identities = 61/174 (35%), Positives = 80/174 (45%), Gaps = 12/174 (6%)
Frame = +3
Query: 45 PGYRPAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECE 218
PG A DECA C D LC NT SY C C+ GY+ +G C D+DEC
Sbjct: 34 PGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCEDIDECG 91
Query: 219 RDTH-TCQQICSNTEGSYECSCEDGY--EKRGDACVDINECHE-EGVCPSPGRCVNLLGS 386
+ + C C N G+Y C+C DG+ G C+D++EC E G C CVN++GS
Sbjct: 92 NELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH--TCVNVMGS 149
Query: 387 FRCVCPRGYRLDAEGARCVDRDE----CAQTGR-CQAPCRNY-AGGYRCDCPVG 530
+ C C G+ L C+ R E C C C+ G C+C G
Sbjct: 150 YECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPG 203
Score = 74.1 bits (174), Expect = 3e-13
Identities = 55/211 (26%), Positives = 81/211 (38%), Gaps = 37/211 (17%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRG---VRGRDE---CAVRPPPCDQLCHNTD-GSYDCLCRTG 167
VN +GS+ C C G+ + + +E C + C +C GS C CR G
Sbjct: 144 VNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPG 203
Query: 168 YELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE---------KRGDACVD 320
+EL ++ +C + C CQ C +T ECSC Y+ +R D ++
Sbjct: 204 FELAKNQRDC--ILTCNHGNGGCQHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLE 261
Query: 321 INECHEEGVCPSPGR--------------------CVNLLGSFRCVCPRGYRLDAEGARC 440
+ E + V R C + C CP G+ L +G C
Sbjct: 262 VTESNTTSVVDGDKRVKRRLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTC 321
Query: 441 VDRDEC-AQTGRCQAPCRNYAGGYRCDCPVG 530
D DEC + G C C+N G + C C G
Sbjct: 322 KDIDECQTRNGGCDHFCKNIVGSFDCGCKKG 352
Score = 56.0 bits (129), Expect = 8e-08
Identities = 26/67 (38%), Positives = 37/67 (55%), Gaps = 1/67 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRG-RDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
+N G+F C C GY G G +EC++ C Q+C NT GSY+C C GY+L +
Sbjct: 379 INHPGTFACACNRGYTLYGFTHCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWN 438
Query: 186 GANCRDV 206
+C +V
Sbjct: 439 KKDCVEV 445
Score = 54.8 bits (126), Expect = 2e-07
Identities = 30/82 (36%), Positives = 41/82 (50%), Gaps = 4/82 (4%)
Frame = +3
Query: 318 DINECHEEGV--CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ--TGRCQAP 485
D++EC +G+ C + C N S++C C GY+ EG +C D DEC G C
Sbjct: 45 DVDEC-AQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCEDIDECGNELNGGCVHD 101
Query: 486 CRNYAGGYRCDCPVGTVRSPSG 551
C N G YRC C G + + G
Sbjct: 102 CLNIPGNYRCTCFDGFMLAHDG 123
>AJ295142-1|CAC82720.1| 652|Homo sapiens C1q receptor protein
protein.
Length = 652
Score = 122 bits (295), Expect = 6e-28
Identities = 74/187 (39%), Positives = 89/187 (47%), Gaps = 10/187 (5%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCH-NTDG-SYDCLCRTGYELDEDG 188
GSF C C PG+R V R+ C+ P C G +Y C C GY+LD
Sbjct: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCALGPHGKNYTCRCPQGYQLDSSQ 340
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD---ACVDINECHEEGVCPSP 359
+C DVDEC+ C Q C NT G + C C GYE G AC D++EC G P
Sbjct: 341 LDCVDVDECQDSP--CAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDEC-ALGRSPCA 397
Query: 360 GRCVNLLGSFRCVCPRGYRLDAE-GARCVDRDECAQTGR--CQAPCRNYAGGYRCDCPVG 530
C N GSF C C GY L E G +C D DEC G C + C N G + C C G
Sbjct: 398 QGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPG 457
Query: 531 TVRSPSG 551
V +P+G
Sbjct: 458 WVLAPNG 464
Score = 104 bits (250), Expect = 2e-22
Identities = 54/143 (37%), Positives = 69/143 (48%), Gaps = 4/143 (2%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN-CR 200
++ C C GY+ + D + PC Q C NT G + C C GYE G C+
Sbjct: 325 NYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQ 384
Query: 201 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD---ACVDINECHEEGVCPSPGRCV 371
DVDEC C Q C+NT+GS+ CSCE+GY G+ C D++EC G C
Sbjct: 385 DVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCF 444
Query: 372 NLLGSFRCVCPRGYRLDAEGARC 440
N GSF C C G+ L G C
Sbjct: 445 NTQGSFHCGCLPGWVLAPNGVSC 467
Score = 101 bits (243), Expect = 1e-21
Identities = 49/100 (49%), Positives = 57/100 (57%), Gaps = 5/100 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRG---VRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL- 176
VNT G FRC C GY P G G + DECA+ PC Q C NTDGS+ C C GY L
Sbjct: 359 VNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLA 418
Query: 177 DEDGANCRDVDEC-ERDTHTCQQICSNTEGSYECSCEDGY 293
EDG C+DVDEC C +C NT+GS+ C C G+
Sbjct: 419 GEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGW 458
Score = 85.4 bits (202), Expect = 1e-16
Identities = 54/150 (36%), Positives = 65/150 (43%), Gaps = 8/150 (5%)
Frame = +3
Query: 111 CDQLC-HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICS-NTEG-SYECSC 281
C Q C DGS+ C CR G+ L +D C + C C+ G +Y C C
Sbjct: 271 CHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCALGPHGKNYTCRC 330
Query: 282 EDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEG-ARCVDRD 452
GY+ CVD++EC + P CVN G FRC C GY G C D D
Sbjct: 331 PQGYQLDSSQLDCVDVDECQDS---PCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVD 387
Query: 453 ECAQTGR--CQAPCRNYAGGYRCDCPVGTV 536
ECA GR C C N G + C C G V
Sbjct: 388 ECA-LGRSPCAQGCTNTDGSFHCSCEEGYV 416
Score = 72.9 bits (171), Expect = 7e-13
Identities = 41/113 (36%), Positives = 52/113 (46%), Gaps = 7/113 (6%)
Frame = +3
Query: 213 CERDTHTCQQIC-SNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLLG 383
C + C Q C +GS+ C C G+ D C N C P G LG
Sbjct: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSS---PCRGGATCALG 320
Query: 384 ----SFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
++ C CP+GY+LD+ CVD DEC Q C C N GG+RC+C VG
Sbjct: 321 PHGKNYTCRCPQGYQLDSSQLDCVDVDEC-QDSPCAQECVNTPGGFRCECWVG 372
>U94333-1|AAB53110.1| 652|Homo sapiens C1qR(p) protein.
Length = 652
Score = 122 bits (294), Expect = 8e-28
Identities = 74/187 (39%), Positives = 89/187 (47%), Gaps = 10/187 (5%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCH-NTDG-SYDCLCRTGYELDEDG 188
GSF C C PG+R V R+ C+ P C G +Y C C GY+LD
Sbjct: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQ 340
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD---ACVDINECHEEGVCPSP 359
+C DVDEC+ C Q C NT G + C C GYE G AC D++EC G P
Sbjct: 341 LDCVDVDECQDSP--CAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDEC-ALGRSPCA 397
Query: 360 GRCVNLLGSFRCVCPRGYRLDAE-GARCVDRDECAQTGR--CQAPCRNYAGGYRCDCPVG 530
C N GSF C C GY L E G +C D DEC G C + C N G + C C G
Sbjct: 398 QGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPG 457
Query: 531 TVRSPSG 551
V +P+G
Sbjct: 458 WVLAPNG 464
Score = 104 bits (250), Expect = 2e-22
Identities = 54/143 (37%), Positives = 69/143 (48%), Gaps = 4/143 (2%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN-CR 200
++ C C GY+ + D + PC Q C NT G + C C GYE G C+
Sbjct: 325 NYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQ 384
Query: 201 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD---ACVDINECHEEGVCPSPGRCV 371
DVDEC C Q C+NT+GS+ CSCE+GY G+ C D++EC G C
Sbjct: 385 DVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCF 444
Query: 372 NLLGSFRCVCPRGYRLDAEGARC 440
N GSF C C G+ L G C
Sbjct: 445 NTQGSFHCGCLPGWVLAPNGVSC 467
Score = 101 bits (243), Expect = 1e-21
Identities = 49/100 (49%), Positives = 57/100 (57%), Gaps = 5/100 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRG---VRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL- 176
VNT G FRC C GY P G G + DECA+ PC Q C NTDGS+ C C GY L
Sbjct: 359 VNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLA 418
Query: 177 DEDGANCRDVDEC-ERDTHTCQQICSNTEGSYECSCEDGY 293
EDG C+DVDEC C +C NT+GS+ C C G+
Sbjct: 419 GEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGW 458
Score = 84.6 bits (200), Expect = 2e-16
Identities = 55/152 (36%), Positives = 66/152 (43%), Gaps = 10/152 (6%)
Frame = +3
Query: 111 CDQLC-HNTDGSYDCLCRTGYELDEDGANCRDVDECE----RDTHTCQQICSNTEGSYEC 275
C Q C DGS+ C CR G+ L +D C + C R TC + +Y C
Sbjct: 271 CHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATC--VLGPHGKNYTC 328
Query: 276 SCEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEG-ARCVD 446
C GY+ CVD++EC + P CVN G FRC C GY G C D
Sbjct: 329 RCPQGYQLDSSQLDCVDVDECQDS---PCAQECVNTPGGFRCECWVGYEPGGPGEGACQD 385
Query: 447 RDECAQTGR--CQAPCRNYAGGYRCDCPVGTV 536
DECA GR C C N G + C C G V
Sbjct: 386 VDECA-LGRSPCAQGCTNTDGSFHCSCEEGYV 416
Score = 74.1 bits (174), Expect = 3e-13
Identities = 42/113 (37%), Positives = 53/113 (46%), Gaps = 7/113 (6%)
Frame = +3
Query: 213 CERDTHTCQQIC-SNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLLG 383
C + C Q C +GS+ C C G+ D C N C C CV LG
Sbjct: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPC-SSSPCRGGATCV--LG 320
Query: 384 ----SFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
++ C CP+GY+LD+ CVD DEC Q C C N GG+RC+C VG
Sbjct: 321 PHGKNYTCRCPQGYQLDSSQLDCVDVDEC-QDSPCAQECVNTPGGFRCECWVG 372
>BC028075-1|AAH28075.1| 652|Homo sapiens CD93 molecule protein.
Length = 652
Score = 122 bits (294), Expect = 8e-28
Identities = 74/187 (39%), Positives = 89/187 (47%), Gaps = 10/187 (5%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCH-NTDG-SYDCLCRTGYELDEDG 188
GSF C C PG+R V R+ C+ P C G +Y C C GY+LD
Sbjct: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQ 340
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD---ACVDINECHEEGVCPSP 359
+C DVDEC+ C Q C NT G + C C GYE G AC D++EC G P
Sbjct: 341 LDCVDVDECQDSP--CAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDEC-ALGRSPCA 397
Query: 360 GRCVNLLGSFRCVCPRGYRLDAE-GARCVDRDECAQTGR--CQAPCRNYAGGYRCDCPVG 530
C N GSF C C GY L E G +C D DEC G C + C N G + C C G
Sbjct: 398 QGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPG 457
Query: 531 TVRSPSG 551
V +P+G
Sbjct: 458 WVLAPNG 464
Score = 104 bits (250), Expect = 2e-22
Identities = 54/143 (37%), Positives = 69/143 (48%), Gaps = 4/143 (2%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN-CR 200
++ C C GY+ + D + PC Q C NT G + C C GYE G C+
Sbjct: 325 NYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQ 384
Query: 201 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD---ACVDINECHEEGVCPSPGRCV 371
DVDEC C Q C+NT+GS+ CSCE+GY G+ C D++EC G C
Sbjct: 385 DVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCF 444
Query: 372 NLLGSFRCVCPRGYRLDAEGARC 440
N GSF C C G+ L G C
Sbjct: 445 NTQGSFHCGCLPGWVLAPNGVSC 467
Score = 101 bits (243), Expect = 1e-21
Identities = 49/100 (49%), Positives = 57/100 (57%), Gaps = 5/100 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRG---VRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL- 176
VNT G FRC C GY P G G + DECA+ PC Q C NTDGS+ C C GY L
Sbjct: 359 VNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLA 418
Query: 177 DEDGANCRDVDEC-ERDTHTCQQICSNTEGSYECSCEDGY 293
EDG C+DVDEC C +C NT+GS+ C C G+
Sbjct: 419 GEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGW 458
Score = 84.6 bits (200), Expect = 2e-16
Identities = 55/152 (36%), Positives = 66/152 (43%), Gaps = 10/152 (6%)
Frame = +3
Query: 111 CDQLC-HNTDGSYDCLCRTGYELDEDGANCRDVDECE----RDTHTCQQICSNTEGSYEC 275
C Q C DGS+ C CR G+ L +D C + C R TC + +Y C
Sbjct: 271 CHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATC--VLGPHGKNYTC 328
Query: 276 SCEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEG-ARCVD 446
C GY+ CVD++EC + P CVN G FRC C GY G C D
Sbjct: 329 RCPQGYQLDSSQLDCVDVDECQDS---PCAQECVNTPGGFRCECWVGYEPGGPGEGACQD 385
Query: 447 RDECAQTGR--CQAPCRNYAGGYRCDCPVGTV 536
DECA GR C C N G + C C G V
Sbjct: 386 VDECA-LGRSPCAQGCTNTDGSFHCSCEEGYV 416
Score = 74.1 bits (174), Expect = 3e-13
Identities = 42/113 (37%), Positives = 53/113 (46%), Gaps = 7/113 (6%)
Frame = +3
Query: 213 CERDTHTCQQIC-SNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLLG 383
C + C Q C +GS+ C C G+ D C N C C CV LG
Sbjct: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPC-SSSPCRGGATCV--LG 320
Query: 384 ----SFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
++ C CP+GY+LD+ CVD DEC Q C C N GG+RC+C VG
Sbjct: 321 PHGKNYTCRCPQGYQLDSSQLDCVDVDEC-QDSPCAQECVNTPGGFRCECWVG 372
>AL118508-1|CAC00597.1| 652|Homo sapiens complement component 1, q
subcomponent, receptor 1 protein.
Length = 652
Score = 122 bits (294), Expect = 8e-28
Identities = 74/187 (39%), Positives = 89/187 (47%), Gaps = 10/187 (5%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCH-NTDG-SYDCLCRTGYELDEDG 188
GSF C C PG+R V R+ C+ P C G +Y C C GY+LD
Sbjct: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQ 340
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD---ACVDINECHEEGVCPSP 359
+C DVDEC+ C Q C NT G + C C GYE G AC D++EC G P
Sbjct: 341 LDCVDVDECQDSP--CAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDEC-ALGRSPCA 397
Query: 360 GRCVNLLGSFRCVCPRGYRLDAE-GARCVDRDECAQTGR--CQAPCRNYAGGYRCDCPVG 530
C N GSF C C GY L E G +C D DEC G C + C N G + C C G
Sbjct: 398 QGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPG 457
Query: 531 TVRSPSG 551
V +P+G
Sbjct: 458 WVLAPNG 464
Score = 104 bits (250), Expect = 2e-22
Identities = 54/143 (37%), Positives = 69/143 (48%), Gaps = 4/143 (2%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN-CR 200
++ C C GY+ + D + PC Q C NT G + C C GYE G C+
Sbjct: 325 NYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQ 384
Query: 201 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD---ACVDINECHEEGVCPSPGRCV 371
DVDEC C Q C+NT+GS+ CSCE+GY G+ C D++EC G C
Sbjct: 385 DVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCF 444
Query: 372 NLLGSFRCVCPRGYRLDAEGARC 440
N GSF C C G+ L G C
Sbjct: 445 NTQGSFHCGCLPGWVLAPNGVSC 467
Score = 101 bits (243), Expect = 1e-21
Identities = 49/100 (49%), Positives = 57/100 (57%), Gaps = 5/100 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRG---VRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL- 176
VNT G FRC C GY P G G + DECA+ PC Q C NTDGS+ C C GY L
Sbjct: 359 VNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLA 418
Query: 177 DEDGANCRDVDEC-ERDTHTCQQICSNTEGSYECSCEDGY 293
EDG C+DVDEC C +C NT+GS+ C C G+
Sbjct: 419 GEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGW 458
Score = 84.6 bits (200), Expect = 2e-16
Identities = 55/152 (36%), Positives = 66/152 (43%), Gaps = 10/152 (6%)
Frame = +3
Query: 111 CDQLC-HNTDGSYDCLCRTGYELDEDGANCRDVDECE----RDTHTCQQICSNTEGSYEC 275
C Q C DGS+ C CR G+ L +D C + C R TC + +Y C
Sbjct: 271 CHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATC--VLGPHGKNYTC 328
Query: 276 SCEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEG-ARCVD 446
C GY+ CVD++EC + P CVN G FRC C GY G C D
Sbjct: 329 RCPQGYQLDSSQLDCVDVDECQDS---PCAQECVNTPGGFRCECWVGYEPGGPGEGACQD 385
Query: 447 RDECAQTGR--CQAPCRNYAGGYRCDCPVGTV 536
DECA GR C C N G + C C G V
Sbjct: 386 VDECA-LGRSPCAQGCTNTDGSFHCSCEEGYV 416
Score = 74.1 bits (174), Expect = 3e-13
Identities = 42/113 (37%), Positives = 53/113 (46%), Gaps = 7/113 (6%)
Frame = +3
Query: 213 CERDTHTCQQIC-SNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLLG 383
C + C Q C +GS+ C C G+ D C N C C CV LG
Sbjct: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPC-SSSPCRGGATCV--LG 320
Query: 384 ----SFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
++ C CP+GY+LD+ CVD DEC Q C C N GG+RC+C VG
Sbjct: 321 PHGKNYTCRCPQGYQLDSSQLDCVDVDEC-QDSPCAQECVNTPGGFRCECWVG 372
>AF054501-1|AAC39881.1| 161|Homo sapiens latent transforming growth
factor-beta binding protein 4 protein.
Length = 161
Score = 122 bits (294), Expect = 8e-28
Identities = 60/142 (42%), Positives = 78/142 (54%), Gaps = 7/142 (4%)
Frame = +3
Query: 120 LCHNTDGSYDCLCRTGYELDEDGANCRDVDEC-ERDTHTC-QQICSNTEGSYEC--SCED 287
+C NTDGS++C+C G+ D A+C DVDEC ER C Q C N+ GSY C C+
Sbjct: 6 ICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDP 65
Query: 288 GYEKRGDA-CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-A 461
GY + C D++EC C + C NL GSF+C+C +GY +G CVD +EC
Sbjct: 66 GYHAGPEGTCDDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECET 125
Query: 462 QTGRCQAP-CRNYAGGYRCDCP 524
G C A C N G + C CP
Sbjct: 126 LQGVCGAALCENVEGSFLCVCP 147
Score = 114 bits (275), Expect = 2e-25
Identities = 67/155 (43%), Positives = 80/155 (51%), Gaps = 11/155 (7%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPP-C-DQLCHNTDGSYDCL--CRTGYE 173
NT GSF C+C PG+R P DEC R P C Q C N+ GSY C+ C GY
Sbjct: 9 NTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYH 68
Query: 174 LDEDGANCRDVDEC-ERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHE-E 341
+G C DVDEC R +C N GS++C C+ GYE + G CVD+NEC +
Sbjct: 69 AGPEG-TCDDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQ 127
Query: 342 GVCPSPGRCVNLLGSFRCVCPRG-YRLDAEGARCV 443
GVC C N+ GSF CVCP D RCV
Sbjct: 128 GVC-GAALCENVEGSFLCVCPNSPEEFDPMTGRCV 161
Score = 85.0 bits (201), Expect = 2e-16
Identities = 47/108 (43%), Positives = 60/108 (55%), Gaps = 9/108 (8%)
Frame = +3
Query: 234 CQQ-ICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEG--VCPSPGRCVNLLGSFRCV 398
CQ IC+NT+GS+EC C G+ D +C+D++EC E G +C S RC N GS+RCV
Sbjct: 2 CQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQ-RCENSPGSYRCV 60
Query: 399 --CPRGYRLDAEGARCVDRDECAQTGRC--QAPCRNYAGGYRCDCPVG 530
C GY EG C D DEC C A C+N G ++C C G
Sbjct: 61 RDCDPGYHAGPEGT-CDDVDECRNRSFCGAHAVCQNLPGSFQCLCDQG 107
Score = 60.1 bits (139), Expect = 5e-09
Identities = 32/74 (43%), Positives = 39/74 (52%), Gaps = 5/74 (6%)
Frame = +3
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG--RCQAP-CRNYAGGYRC 515
+C S G C N GSF C+CP G+R + A C+D DEC + G C + C N G YRC
Sbjct: 1 LCQS-GICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRC 59
Query: 516 --DCPVGTVRSPSG 551
DC G P G
Sbjct: 60 VRDCDPGYHAGPEG 73
>AB209895-1|BAD93132.1| 671|Homo sapiens complement component 1, q
subcomponent, receptor 1 variant protein.
Length = 671
Score = 122 bits (294), Expect = 8e-28
Identities = 74/187 (39%), Positives = 89/187 (47%), Gaps = 10/187 (5%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCH-NTDG-SYDCLCRTGYELDEDG 188
GSF C C PG+R V R+ C+ P C G +Y C C GY+LD
Sbjct: 300 GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQ 359
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD---ACVDINECHEEGVCPSP 359
+C DVDEC+ C Q C NT G + C C GYE G AC D++EC G P
Sbjct: 360 LDCVDVDECQDSP--CAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDEC-ALGRSPCA 416
Query: 360 GRCVNLLGSFRCVCPRGYRLDAE-GARCVDRDECAQTGR--CQAPCRNYAGGYRCDCPVG 530
C N GSF C C GY L E G +C D DEC G C + C N G + C C G
Sbjct: 417 QGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPG 476
Query: 531 TVRSPSG 551
V +P+G
Sbjct: 477 WVLAPNG 483
Score = 104 bits (250), Expect = 2e-22
Identities = 54/143 (37%), Positives = 69/143 (48%), Gaps = 4/143 (2%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN-CR 200
++ C C GY+ + D + PC Q C NT G + C C GYE G C+
Sbjct: 344 NYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQ 403
Query: 201 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD---ACVDINECHEEGVCPSPGRCV 371
DVDEC C Q C+NT+GS+ CSCE+GY G+ C D++EC G C
Sbjct: 404 DVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCF 463
Query: 372 NLLGSFRCVCPRGYRLDAEGARC 440
N GSF C C G+ L G C
Sbjct: 464 NTQGSFHCGCLPGWVLAPNGVSC 486
Score = 101 bits (243), Expect = 1e-21
Identities = 49/100 (49%), Positives = 57/100 (57%), Gaps = 5/100 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRG---VRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL- 176
VNT G FRC C GY P G G + DECA+ PC Q C NTDGS+ C C GY L
Sbjct: 378 VNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLA 437
Query: 177 DEDGANCRDVDEC-ERDTHTCQQICSNTEGSYECSCEDGY 293
EDG C+DVDEC C +C NT+GS+ C C G+
Sbjct: 438 GEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGW 477
Score = 84.6 bits (200), Expect = 2e-16
Identities = 55/152 (36%), Positives = 66/152 (43%), Gaps = 10/152 (6%)
Frame = +3
Query: 111 CDQLC-HNTDGSYDCLCRTGYELDEDGANCRDVDECE----RDTHTCQQICSNTEGSYEC 275
C Q C DGS+ C CR G+ L +D C + C R TC + +Y C
Sbjct: 290 CHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATC--VLGPHGKNYTC 347
Query: 276 SCEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEG-ARCVD 446
C GY+ CVD++EC + P CVN G FRC C GY G C D
Sbjct: 348 RCPQGYQLDSSQLDCVDVDECQDS---PCAQECVNTPGGFRCECWVGYEPGGPGEGACQD 404
Query: 447 RDECAQTGR--CQAPCRNYAGGYRCDCPVGTV 536
DECA GR C C N G + C C G V
Sbjct: 405 VDECA-LGRSPCAQGCTNTDGSFHCSCEEGYV 435
Score = 74.1 bits (174), Expect = 3e-13
Identities = 42/113 (37%), Positives = 53/113 (46%), Gaps = 7/113 (6%)
Frame = +3
Query: 213 CERDTHTCQQIC-SNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLLG 383
C + C Q C +GS+ C C G+ D C N C C CV LG
Sbjct: 283 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPC-SSSPCRGGATCV--LG 339
Query: 384 ----SFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
++ C CP+GY+LD+ CVD DEC Q C C N GG+RC+C VG
Sbjct: 340 PHGKNYTCRCPQGYQLDSSQLDCVDVDEC-QDSPCAQECVNTPGGFRCECWVG 391
>U69263-1|AAC51260.2| 956|Homo sapiens matrilin-2 precursor
protein.
Length = 956
Score = 122 bits (293), Expect = 1e-27
Identities = 64/187 (34%), Positives = 89/187 (47%), Gaps = 6/187 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VNT S+ C C G+ P + R + CA+ P C+ C N + SY C C GY LD
Sbjct: 377 VNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDP 436
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINEC-HEEGVCP 353
+G C VD C + H C+Q+C NTE S+ C C +G+ D C ++ C + C
Sbjct: 437 NGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCE 496
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQAPCRNYAGGYRCDCPVG 530
CVN+ SF C CP G+ L ++G C D CA C+ C + + C C G
Sbjct: 497 Y--SCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEG 554
Query: 531 TVRSPSG 551
+ G
Sbjct: 555 YILREDG 561
Score = 118 bits (285), Expect = 1e-26
Identities = 64/186 (34%), Positives = 85/186 (45%), Gaps = 5/186 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+N GS+ C C GY R +D CA+ C+QLC N GS+ C C +GY L E
Sbjct: 254 INIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALAE 313
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPS 356
DG C VD C + H C+ C N +GSY C C +G+ D C I+ C
Sbjct: 314 DGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSN-HGC 372
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRCDCPVGT 533
CVN S+ C C +G+ L+ + C + CA C+ C N Y C C G
Sbjct: 373 QHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGY 432
Query: 534 VRSPSG 551
P+G
Sbjct: 433 TLDPNG 438
Score = 112 bits (269), Expect = 9e-25
Identities = 55/155 (35%), Positives = 71/155 (45%), Gaps = 3/155 (1%)
Frame = +3
Query: 90 CAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSY 269
C+ C C N GSY C C+ GY L+ D CR D C + H C+Q+C N GS+
Sbjct: 242 CSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSF 301
Query: 270 ECSCEDGY--EKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCV 443
C C GY + G CV ++ C E CVN GS+ C C G+ L+ + C
Sbjct: 302 VCQCYSGYALAEDGKRCVAVDYCASEN-HGCEHECVNADGSYLCQCHEGFALNPDKKTCT 360
Query: 444 DRDECAQTGR-CQAPCRNYAGGYRCDCPVGTVRSP 545
D CA + CQ C N Y C C G +P
Sbjct: 361 KIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNP 395
Score = 107 bits (256), Expect = 3e-23
Identities = 61/189 (32%), Positives = 82/189 (43%), Gaps = 8/189 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+NT SF C C G+ + D C + C+ C N D S+ C C G+ L
Sbjct: 459 LNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRS 518
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPG 362
DG C +D C H C+ C ++E S+ C C +GY R D C + VC +
Sbjct: 519 DGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDG----KTCRRKDVCQAID 574
Query: 363 R-----CVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQAPCRNYAGGYRCDCP 524
CVN S+ C C G+RL +G RC +D C T C+ C N Y C C
Sbjct: 575 HGCEHICVNSDDSYTCECLVGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCS 634
Query: 525 VGTVRSPSG 551
G V + G
Sbjct: 635 EGFVLAEDG 643
Score = 97.1 bits (231), Expect = 4e-20
Identities = 53/151 (35%), Positives = 70/151 (46%), Gaps = 7/151 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN SF C C G+ R G+ D CA+ C+ C +++ S+ C C GY L E
Sbjct: 500 VNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILRE 559
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPG 362
DG CR D C+ H C+ IC N++ SY C C G+ D C + VC S
Sbjct: 560 DGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLVGFRLAEDG----KRCRRKDVCKSTH 615
Query: 363 R-----CVNLLGSFRCVCPRGYRLDAEGARC 440
CVN S+ C C G+ L +G RC
Sbjct: 616 HGCEHICVNNGNSYICKCSEGFVLAEDGRRC 646
Score = 53.2 bits (122), Expect = 6e-07
Identities = 26/70 (37%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN+ S+ C C G+R A G+ R +D C C+ +C N SY C C G+ L E
Sbjct: 582 VNSDDSYTCECLVGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAE 641
Query: 183 DGANCRDVDE 212
DG C+ E
Sbjct: 642 DGRRCKKCTE 651
>BC016394-1|AAH16394.1| 715|Homo sapiens MATN2 protein protein.
Length = 715
Score = 122 bits (293), Expect = 1e-27
Identities = 64/187 (34%), Positives = 89/187 (47%), Gaps = 6/187 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VNT S+ C C G+ P + R + CA+ P C+ C N + SY C C GY LD
Sbjct: 136 VNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDP 195
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINEC-HEEGVCP 353
+G C VD C + H C+Q+C NTE S+ C C +G+ D C ++ C + C
Sbjct: 196 NGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCE 255
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQAPCRNYAGGYRCDCPVG 530
CVN+ SF C CP G+ L ++G C D CA C+ C + + C C G
Sbjct: 256 Y--SCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEG 313
Query: 531 TVRSPSG 551
+ G
Sbjct: 314 YILREDG 320
Score = 118 bits (285), Expect = 1e-26
Identities = 64/186 (34%), Positives = 85/186 (45%), Gaps = 5/186 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+N GS+ C C GY R +D CA+ C+QLC N GS+ C C +GY L E
Sbjct: 13 INIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALAE 72
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPS 356
DG C VD C + H C+ C N +GSY C C +G+ D C I+ C
Sbjct: 73 DGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDEKTCTKIDYCASSN-HGC 131
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRCDCPVGT 533
CVN S+ C C +G+ L+ + C + CA C+ C N Y C C G
Sbjct: 132 QHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGY 191
Query: 534 VRSPSG 551
P+G
Sbjct: 192 TLDPNG 197
Score = 112 bits (269), Expect = 9e-25
Identities = 55/155 (35%), Positives = 71/155 (45%), Gaps = 3/155 (1%)
Frame = +3
Query: 90 CAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSY 269
C+ C C N GSY C C+ GY L+ D CR D C + H C+Q+C N GS+
Sbjct: 1 CSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSF 60
Query: 270 ECSCEDGY--EKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCV 443
C C GY + G CV ++ C E CVN GS+ C C G+ L+ + C
Sbjct: 61 VCQCYSGYALAEDGKRCVAVDYCASEN-HGCEHECVNADGSYLCQCHEGFALNPDEKTCT 119
Query: 444 DRDECAQTGR-CQAPCRNYAGGYRCDCPVGTVRSP 545
D CA + CQ C N Y C C G +P
Sbjct: 120 KIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNP 154
Score = 108 bits (259), Expect = 1e-23
Identities = 61/189 (32%), Positives = 82/189 (43%), Gaps = 8/189 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+NT SF C C G+ + D C + C+ C N D S+ C C G+ L
Sbjct: 218 LNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRS 277
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPG 362
DG C +D C H C+ C ++E S+ C C +GY R D C + VC +
Sbjct: 278 DGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDG----KTCRRKDVCQAID 333
Query: 363 R-----CVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQAPCRNYAGGYRCDCP 524
CVN S+ C C G+RL +G RC +D C T C+ C N Y C C
Sbjct: 334 HGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCS 393
Query: 525 VGTVRSPSG 551
G V + G
Sbjct: 394 EGFVLAEDG 402
Score = 99.1 bits (236), Expect = 9e-21
Identities = 53/151 (35%), Positives = 71/151 (47%), Gaps = 7/151 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN SF C C G+ R G+ D CA+ C+ C +++ S+ C C GY L E
Sbjct: 259 VNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILRE 318
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPG 362
DG CR D C+ H C+ IC N++ SY C C +G+ D C + VC S
Sbjct: 319 DGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDG----KRCRRKDVCKSTH 374
Query: 363 R-----CVNLLGSFRCVCPRGYRLDAEGARC 440
CVN S+ C C G+ L +G RC
Sbjct: 375 HGCEHICVNNGNSYICKCSEGFVLAEDGRRC 405
Score = 53.6 bits (123), Expect = 4e-07
Identities = 26/70 (37%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN+ S+ C C G+R A G+ R +D C C+ +C N SY C C G+ L E
Sbjct: 341 VNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAE 400
Query: 183 DGANCRDVDE 212
DG C+ E
Sbjct: 401 DGRRCKKCTE 410
>BC010444-1|AAH10444.1| 937|Homo sapiens matrilin 2 protein.
Length = 937
Score = 122 bits (293), Expect = 1e-27
Identities = 64/187 (34%), Positives = 89/187 (47%), Gaps = 6/187 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VNT S+ C C G+ P + R + CA+ P C+ C N + SY C C GY LD
Sbjct: 377 VNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDP 436
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINEC-HEEGVCP 353
+G C VD C + H C+Q+C NTE S+ C C +G+ D C ++ C + C
Sbjct: 437 NGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCE 496
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQAPCRNYAGGYRCDCPVG 530
CVN+ SF C CP G+ L ++G C D CA C+ C + + C C G
Sbjct: 497 Y--SCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEG 554
Query: 531 TVRSPSG 551
+ G
Sbjct: 555 YILREDG 561
Score = 118 bits (285), Expect = 1e-26
Identities = 64/186 (34%), Positives = 85/186 (45%), Gaps = 5/186 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+N GS+ C C GY R +D CA+ C+QLC N GS+ C C +GY L E
Sbjct: 254 INIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALAE 313
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPS 356
DG C VD C + H C+ C N +GSY C C +G+ D C I+ C
Sbjct: 314 DGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDEKTCTKIDYCASSN-HGC 372
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRCDCPVGT 533
CVN S+ C C +G+ L+ + C + CA C+ C N Y C C G
Sbjct: 373 QHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGY 432
Query: 534 VRSPSG 551
P+G
Sbjct: 433 TLDPNG 438
Score = 112 bits (269), Expect = 9e-25
Identities = 55/155 (35%), Positives = 71/155 (45%), Gaps = 3/155 (1%)
Frame = +3
Query: 90 CAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSY 269
C+ C C N GSY C C+ GY L+ D CR D C + H C+Q+C N GS+
Sbjct: 242 CSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSF 301
Query: 270 ECSCEDGY--EKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCV 443
C C GY + G CV ++ C E CVN GS+ C C G+ L+ + C
Sbjct: 302 VCQCYSGYALAEDGKRCVAVDYCASEN-HGCEHECVNADGSYLCQCHEGFALNPDEKTCT 360
Query: 444 DRDECAQTGR-CQAPCRNYAGGYRCDCPVGTVRSP 545
D CA + CQ C N Y C C G +P
Sbjct: 361 KIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNP 395
Score = 108 bits (259), Expect = 1e-23
Identities = 61/189 (32%), Positives = 82/189 (43%), Gaps = 8/189 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+NT SF C C G+ + D C + C+ C N D S+ C C G+ L
Sbjct: 459 LNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRS 518
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPG 362
DG C +D C H C+ C ++E S+ C C +GY R D C + VC +
Sbjct: 519 DGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDG----KTCRRKDVCQAID 574
Query: 363 R-----CVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQAPCRNYAGGYRCDCP 524
CVN S+ C C G+RL +G RC +D C T C+ C N Y C C
Sbjct: 575 HGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCS 634
Query: 525 VGTVRSPSG 551
G V + G
Sbjct: 635 EGFVLAEDG 643
Score = 99.1 bits (236), Expect = 9e-21
Identities = 53/151 (35%), Positives = 71/151 (47%), Gaps = 7/151 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN SF C C G+ R G+ D CA+ C+ C +++ S+ C C GY L E
Sbjct: 500 VNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILRE 559
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPG 362
DG CR D C+ H C+ IC N++ SY C C +G+ D C + VC S
Sbjct: 560 DGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDG----KRCRRKDVCKSTH 615
Query: 363 R-----CVNLLGSFRCVCPRGYRLDAEGARC 440
CVN S+ C C G+ L +G RC
Sbjct: 616 HGCEHICVNNGNSYICKCSEGFVLAEDGRRC 646
Score = 53.6 bits (123), Expect = 4e-07
Identities = 26/70 (37%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN+ S+ C C G+R A G+ R +D C C+ +C N SY C C G+ L E
Sbjct: 582 VNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAE 641
Query: 183 DGANCRDVDE 212
DG C+ E
Sbjct: 642 DGRRCKKCTE 651
>AL833931-1|CAD38787.1| 1016|Homo sapiens hypothetical protein
protein.
Length = 1016
Score = 122 bits (293), Expect = 1e-27
Identities = 64/187 (34%), Positives = 89/187 (47%), Gaps = 6/187 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VNT S+ C C G+ P + R + CA+ P C+ C N + SY C C GY LD
Sbjct: 437 VNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDP 496
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINEC-HEEGVCP 353
+G C VD C + H C+Q+C NTE S+ C C +G+ D C ++ C + C
Sbjct: 497 NGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCE 556
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQAPCRNYAGGYRCDCPVG 530
CVN+ SF C CP G+ L ++G C D CA C+ C + + C C G
Sbjct: 557 Y--SCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEG 614
Query: 531 TVRSPSG 551
+ G
Sbjct: 615 YILREDG 621
Score = 118 bits (285), Expect = 1e-26
Identities = 64/186 (34%), Positives = 85/186 (45%), Gaps = 5/186 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+N GS+ C C GY R +D CA+ C+QLC N GS+ C C +GY L E
Sbjct: 314 INIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALAE 373
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPS 356
DG C VD C + H C+ C N +GSY C C +G+ D C I+ C
Sbjct: 374 DGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDEKTCTKIDYCASSN-HGC 432
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRCDCPVGT 533
CVN S+ C C +G+ L+ + C + CA C+ C N Y C C G
Sbjct: 433 QHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGY 492
Query: 534 VRSPSG 551
P+G
Sbjct: 493 TLDPNG 498
Score = 112 bits (269), Expect = 9e-25
Identities = 55/155 (35%), Positives = 71/155 (45%), Gaps = 3/155 (1%)
Frame = +3
Query: 90 CAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSY 269
C+ C C N GSY C C+ GY L+ D CR D C + H C+Q+C N GS+
Sbjct: 302 CSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSF 361
Query: 270 ECSCEDGY--EKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCV 443
C C GY + G CV ++ C E CVN GS+ C C G+ L+ + C
Sbjct: 362 VCQCYSGYALAEDGKRCVAVDYCASEN-HGCEHECVNADGSYLCQCHEGFALNPDEKTCT 420
Query: 444 DRDECAQTGR-CQAPCRNYAGGYRCDCPVGTVRSP 545
D CA + CQ C N Y C C G +P
Sbjct: 421 KIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNP 455
Score = 108 bits (259), Expect = 1e-23
Identities = 61/189 (32%), Positives = 82/189 (43%), Gaps = 8/189 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+NT SF C C G+ + D C + C+ C N D S+ C C G+ L
Sbjct: 519 LNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRS 578
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPG 362
DG C +D C H C+ C ++E S+ C C +GY R D C + VC +
Sbjct: 579 DGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDG----KTCRRKDVCQAID 634
Query: 363 R-----CVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQAPCRNYAGGYRCDCP 524
CVN S+ C C G+RL +G RC +D C T C+ C N Y C C
Sbjct: 635 HGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCS 694
Query: 525 VGTVRSPSG 551
G V + G
Sbjct: 695 EGFVLAEDG 703
Score = 99.1 bits (236), Expect = 9e-21
Identities = 53/151 (35%), Positives = 71/151 (47%), Gaps = 7/151 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN SF C C G+ R G+ D CA+ C+ C +++ S+ C C GY L E
Sbjct: 560 VNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILRE 619
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPG 362
DG CR D C+ H C+ IC N++ SY C C +G+ D C + VC S
Sbjct: 620 DGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDG----KRCRRKDVCKSTH 675
Query: 363 R-----CVNLLGSFRCVCPRGYRLDAEGARC 440
CVN S+ C C G+ L +G RC
Sbjct: 676 HGCEHICVNNGNSYICKCSEGFVLAEDGRRC 706
Score = 53.6 bits (123), Expect = 4e-07
Identities = 26/70 (37%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN+ S+ C C G+R A G+ R +D C C+ +C N SY C C G+ L E
Sbjct: 642 VNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAE 701
Query: 183 DGANCRDVDE 212
DG C+ E
Sbjct: 702 DGRRCKKCTE 711
>AK075489-1|BAC11648.1| 451|Homo sapiens rase 7. protein.
Length = 451
Score = 118 bits (285), Expect = 1e-26
Identities = 64/186 (34%), Positives = 85/186 (45%), Gaps = 5/186 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+N GS+ C C GY R +D CA+ C+QLC N GS+ C C +GY L E
Sbjct: 254 INIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALAE 313
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPS 356
DG C VD C + H C+ C N +GSY C C +G+ D C I+ C
Sbjct: 314 DGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSN-HGC 372
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRCDCPVGT 533
CVN S+ C C +G+ L+ + C + CA C+ C N Y C C G
Sbjct: 373 QHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGY 432
Query: 534 VRSPSG 551
P+G
Sbjct: 433 TLDPNG 438
Score = 112 bits (269), Expect = 9e-25
Identities = 55/155 (35%), Positives = 71/155 (45%), Gaps = 3/155 (1%)
Frame = +3
Query: 90 CAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSY 269
C+ C C N GSY C C+ GY L+ D CR D C + H C+Q+C N GS+
Sbjct: 242 CSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSF 301
Query: 270 ECSCEDGY--EKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCV 443
C C GY + G CV ++ C E CVN GS+ C C G+ L+ + C
Sbjct: 302 VCQCYSGYALAEDGKRCVAVDYCASEN-HGCEHECVNADGSYLCQCHEGFALNPDKKTCT 360
Query: 444 DRDECAQTGR-CQAPCRNYAGGYRCDCPVGTVRSP 545
D CA + CQ C N Y C C G +P
Sbjct: 361 KIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNP 395
Score = 109 bits (262), Expect = 6e-24
Identities = 61/151 (40%), Positives = 69/151 (45%), Gaps = 7/151 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN GSF C C GY A G R D CA C+ C N DGSY C C G+ L+
Sbjct: 295 VNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNP 354
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPS 356
D C +D C H CQ C NT+ SY C C G+ D C IN C
Sbjct: 355 DKKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYC----ALNK 410
Query: 357 PG---RCVNLLGSFRCVCPRGYRLDAEGARC 440
PG CVN+ S+ C C RGY LD G C
Sbjct: 411 PGCEHECVNMEESYYCRCHRGYTLDPNGKTC 441
>X12892-1|CAA31383.1| 650|Homo sapiens protein ( H.sapiens mRNA for
protein S. ).
Length = 650
Score = 112 bits (269), Expect = 9e-25
Identities = 56/156 (35%), Positives = 83/156 (53%), Gaps = 10/156 (6%)
Frame = +3
Query: 84 DECAVRPPPCDQ----LCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHT---CQ 239
D+C+ P PC++ C + S+ C C+ G++ G C D++EC+ ++ C
Sbjct: 93 DQCS--PLPCNEDGYMSCKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCS 146
Query: 240 QICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGY 413
QIC NT GSY CSC++G+ + C D++EC + C N+LG F C CP GY
Sbjct: 147 QICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNILGDFECECPEGY 206
Query: 414 RLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
R + + C D DEC++ C C NY GG+ C C
Sbjct: 207 RYNLKSKSCEDIDECSE-NMCAQLCVNYPGGHTCYC 241
Score = 93.1 bits (221), Expect = 6e-19
Identities = 51/149 (34%), Positives = 74/149 (49%), Gaps = 10/149 (6%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPP-----CDQLCHNTDGSYDCLCRTGYELDEDG 188
SF C C PG++ + +EC + P C Q+C NT GSY C C+ G+ + +
Sbjct: 114 SFTCTCKPGWQ-GEKCEFDINEC--KDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNK 170
Query: 189 ANCRDVDECERDTHTC-QQICSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCPSP 359
+C+DVDEC C +C N G +EC C +G Y + +C DI+EC E +C
Sbjct: 171 KDCKDVDECSLKPSICGTAVCKNILGDFECECPEGYRYNLKSKSCEDIDEC-SENMCAQ- 228
Query: 360 GRCVNLLGSFRCVC--PRGYRLDAEGARC 440
CVN G C C +G++L + C
Sbjct: 229 -LCVNYPGGHTCYCDGKKGFKLAQDQKSC 256
Score = 71.3 bits (167), Expect = 2e-12
Identities = 38/116 (32%), Positives = 55/116 (47%), Gaps = 3/116 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
NT GS+ C C G+ + + DEC+++P C +C N G ++C C GY +
Sbjct: 151 NTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNILGDFECECPEGYRYNL 210
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVC 350
+C D+DEC + C Q+C N G + C C DG +K D C VC
Sbjct: 211 KSKSCEDIDECSENM--CAQLCVNYPGGHTCYC-DG-KKGFKLAQDQKSCEVVSVC 262
Score = 64.5 bits (150), Expect = 2e-10
Identities = 35/102 (34%), Positives = 53/102 (51%), Gaps = 7/102 (6%)
Frame = +3
Query: 246 CSNTEGSYECSCEDGYEKRGDAC-VDINECHE----EGVCPSPGRCVNLLGSFRCVCPRG 410
C + + S+ C+C+ G++ G+ C DINEC + G C C N GS+ C C G
Sbjct: 108 CKDGKASFTCTCKPGWQ--GEKCEFDINECKDPSNINGGCSQI--CDNTPGSYHCSCKNG 163
Query: 411 YRLDAEGARCVDRDECA-QTGRC-QAPCRNYAGGYRCDCPVG 530
+ + + C D DEC+ + C A C+N G + C+CP G
Sbjct: 164 FVMLSNKKDCKDVDECSLKPSICGTAVCKNILGDFECECPEG 205
Score = 36.7 bits (81), Expect = 0.054
Identities = 26/82 (31%), Positives = 34/82 (41%), Gaps = 5/82 (6%)
Frame = +3
Query: 306 DACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQ----TG 470
D C + C+E+G C + SF C C G+ +G +C D +EC G
Sbjct: 93 DQCSPL-PCNEDGYMS----CKDGKASFTCTCKPGW----QGEKCEFDINECKDPSNING 143
Query: 471 RCQAPCRNYAGGYRCDCPVGTV 536
C C N G Y C C G V
Sbjct: 144 GCSQICDNTPGSYHCSCKNGFV 165
>M14338-1|AAA60181.1| 650|Homo sapiens protein S precursor protein.
Length = 650
Score = 112 bits (269), Expect = 9e-25
Identities = 56/156 (35%), Positives = 83/156 (53%), Gaps = 10/156 (6%)
Frame = +3
Query: 84 DECAVRPPPCDQ----LCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHT---CQ 239
D+C+ P PC++ C + S+ C C+ G++ G C D++EC+ ++ C
Sbjct: 93 DQCS--PLPCNEDGYMSCKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCS 146
Query: 240 QICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGY 413
QIC NT GSY CSC++G+ + C D++EC + C N+LG F C CP GY
Sbjct: 147 QICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNILGDFECECPEGY 206
Query: 414 RLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
R + + C D DEC++ C C NY GG+ C C
Sbjct: 207 RYNLKSKSCEDIDECSE-NMCAQLCVNYPGGHTCYC 241
Score = 93.1 bits (221), Expect = 6e-19
Identities = 51/149 (34%), Positives = 74/149 (49%), Gaps = 10/149 (6%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPP-----CDQLCHNTDGSYDCLCRTGYELDEDG 188
SF C C PG++ + +EC + P C Q+C NT GSY C C+ G+ + +
Sbjct: 114 SFTCTCKPGWQ-GEKCEFDINEC--KDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNK 170
Query: 189 ANCRDVDECERDTHTC-QQICSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCPSP 359
+C+DVDEC C +C N G +EC C +G Y + +C DI+EC E +C
Sbjct: 171 KDCKDVDECSLKPSICGTAVCKNILGDFECECPEGYRYNLKSKSCEDIDEC-SENMCAQ- 228
Query: 360 GRCVNLLGSFRCVC--PRGYRLDAEGARC 440
CVN G C C +G++L + C
Sbjct: 229 -LCVNYPGGHTCYCDGKKGFKLAQDQKSC 256
Score = 71.3 bits (167), Expect = 2e-12
Identities = 38/116 (32%), Positives = 55/116 (47%), Gaps = 3/116 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDE 182
NT GS+ C C G+ + + DEC+++P C +C N G ++C C GY +
Sbjct: 151 NTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNILGDFECECPEGYRYNL 210
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVC 350
+C D+DEC + C Q+C N G + C C DG +K D C VC
Sbjct: 211 KSKSCEDIDECSENM--CAQLCVNYPGGHTCYC-DG-KKGFKLAQDQKSCEVVSVC 262
Score = 64.5 bits (150), Expect = 2e-10
Identities = 35/102 (34%), Positives = 53/102 (51%), Gaps = 7/102 (6%)
Frame = +3
Query: 246 CSNTEGSYECSCEDGYEKRGDAC-VDINECHE----EGVCPSPGRCVNLLGSFRCVCPRG 410
C + + S+ C+C+ G++ G+ C DINEC + G C C N GS+ C C G
Sbjct: 108 CKDGKASFTCTCKPGWQ--GEKCEFDINECKDPSNINGGCSQI--CDNTPGSYHCSCKNG 163
Query: 411 YRLDAEGARCVDRDECA-QTGRC-QAPCRNYAGGYRCDCPVG 530
+ + + C D DEC+ + C A C+N G + C+CP G
Sbjct: 164 FVMLSNKKDCKDVDECSLKPSICGTAVCKNILGDFECECPEG 205
Score = 36.7 bits (81), Expect = 0.054
Identities = 26/82 (31%), Positives = 34/82 (41%), Gaps = 5/82 (6%)
Frame = +3
Query: 306 DACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQ----TG 470
D C + C+E+G C + SF C C G+ +G +C D +EC G
Sbjct: 93 DQCSPL-PCNEDGYMS----CKDGKASFTCTCKPGW----QGEKCEFDINECKDPSNING 143
Query: 471 RCQAPCRNYAGGYRCDCPVGTV 536
C C N G Y C C G V
Sbjct: 144 GCSQICDNTPGSYHCSCKNGFV 165
>AY358336-1|AAQ88702.1| 509|Homo sapiens DFLL295 protein.
Length = 509
Score = 111 bits (268), Expect = 1e-24
Identities = 68/182 (37%), Positives = 86/182 (47%), Gaps = 11/182 (6%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGV-RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
IG +C C PGY AG+ + +EC ++P PC C NT GSY C C GY L DG +
Sbjct: 70 IGPNKCKCHPGY--AGKTCNQDLNECGLKPRPCKHRCMNTYGSYKCYCLNGYMLMPDG-S 126
Query: 195 CRDVDECERDTHTCQQICSNTEGSYECSCED---GYEKRGDACVDINECHE-EGVCPSPG 362
C C CQ C +G C C G CVD++EC CP
Sbjct: 127 CSSALTC--SMANCQYGCDVVKGQIRCQCPSPGLHLAPDGRTCVDVDECATGRASCPRFR 184
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGAR--CVDRDECAQTGRCQ----APCRNYAGGYRCDCP 524
+CVN GS+ C C +G+ L G + C D DEC+ G+ Q A C N G Y+C C
Sbjct: 185 QCVNTFGSYICKCHKGFDLMYIGGKYQCHDIDECS-LGQYQCSSFARCYNVRGSYKCKCK 243
Query: 525 VG 530
G
Sbjct: 244 EG 245
Score = 87.0 bits (206), Expect = 4e-17
Identities = 56/156 (35%), Positives = 73/156 (46%), Gaps = 9/156 (5%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRG-VRGRDECAVRPPPCDQLCHNTDGSYDCLCRT-GYEL 176
R +NT GS++C C GY G C++ C C G C C + G L
Sbjct: 103 RCMNTYGSYKCYCLNGYMLMPDGSCSSALTCSMAN--CQYGCDVVKGQIRCQCPSPGLHL 160
Query: 177 DEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKR---GD-ACVDINECH- 335
DG C DVDEC +C + C NT GSY C C G++ G C DI+EC
Sbjct: 161 APDGRTCVDVDECATGRASCPRFRQCVNTFGSYICKCHKGFDLMYIGGKYQCHDIDECSL 220
Query: 336 EEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCV 443
+ C S RC N+ GS++C C GY+ +G CV
Sbjct: 221 GQYQCSSFARCYNVRGSYKCKCKEGYQ--GDGLTCV 254
Score = 79.8 bits (188), Expect = 6e-15
Identities = 44/110 (40%), Positives = 53/110 (48%), Gaps = 9/110 (8%)
Frame = +3
Query: 21 GSFRCVC-GPGYR--PAGRGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGYELDED 185
G RC C PG P GR DECA C + C NT GSY C C G++L
Sbjct: 147 GQIRCQCPSPGLHLAPDGRTCVDVDECATGRASCPRFRQCVNTFGSYICKCHKGFDLMYI 206
Query: 186 GAN--CRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDACVDI 323
G C D+DEC + C C N GSY+C C++GY+ G CV I
Sbjct: 207 GGKYQCHDIDECSLGQYQCSSFARCYNVRGSYKCKCKEGYQGDGLTCVYI 256
Score = 35.1 bits (77), Expect = 0.17
Identities = 23/66 (34%), Positives = 29/66 (43%), Gaps = 2/66 (3%)
Frame = +3
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGR-CQAPCRNYAGGYRCDCPVGT 533
G C+ G +C C GY G C D +EC R C+ C N G Y+C C G
Sbjct: 67 GECI---GPNKCKCHPGYA----GKTCNQDLNECGLKPRPCKHRCMNTYGSYKCYCLNGY 119
Query: 534 VRSPSG 551
+ P G
Sbjct: 120 MLMPDG 125
>Y00692-1|CAA68687.1| 676|Homo sapiens preproprotein S protein.
Length = 676
Score = 111 bits (267), Expect = 2e-24
Identities = 56/156 (35%), Positives = 82/156 (52%), Gaps = 10/156 (6%)
Frame = +3
Query: 84 DECAVRPPPCDQ----LCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHT---CQ 239
D+C+ P PC++ C + S+ C C+ G++ G C D++EC+ ++ C
Sbjct: 119 DQCS--PLPCNEDGYMSCKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCS 172
Query: 240 QICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGY 413
QIC NT GSY CSC++G+ + C D++EC + C N+ G F C CP GY
Sbjct: 173 QICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY 232
Query: 414 RLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
R + + C D DEC++ C C NY GGY C C
Sbjct: 233 RYNLKSKSCEDIDECSE-NMCAQLCVNYPGGYTCYC 267
Score = 95.5 bits (227), Expect = 1e-19
Identities = 51/149 (34%), Positives = 75/149 (50%), Gaps = 10/149 (6%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPP-----CDQLCHNTDGSYDCLCRTGYELDEDG 188
SF C C PG++ + +EC + P C Q+C NT GSY C C+ G+ + +
Sbjct: 140 SFTCTCKPGWQ-GEKCEFDINEC--KDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNK 196
Query: 189 ANCRDVDECERDTHTC-QQICSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCPSP 359
+C+DVDEC C +C N G +EC C +G Y + +C DI+EC E +C
Sbjct: 197 KDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDEC-SENMCAQ- 254
Query: 360 GRCVNLLGSFRCVC--PRGYRLDAEGARC 440
CVN G + C C +G++L + C
Sbjct: 255 -LCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
Score = 74.5 bits (175), Expect = 2e-13
Identities = 39/116 (33%), Positives = 55/116 (47%), Gaps = 3/116 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDE 182
NT GS+ C C G+ + + DEC+++P C +C N G ++C C GY +
Sbjct: 177 NTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNL 236
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVC 350
+C D+DEC + C Q+C N G Y C C DG +K D C VC
Sbjct: 237 KSKSCEDIDECSE--NMCAQLCVNYPGGYTCYC-DG-KKGFKLAQDQKSCEVVSVC 288
Score = 64.5 bits (150), Expect = 2e-10
Identities = 35/102 (34%), Positives = 53/102 (51%), Gaps = 7/102 (6%)
Frame = +3
Query: 246 CSNTEGSYECSCEDGYEKRGDAC-VDINECHE----EGVCPSPGRCVNLLGSFRCVCPRG 410
C + + S+ C+C+ G++ G+ C DINEC + G C C N GS+ C C G
Sbjct: 134 CKDGKASFTCTCKPGWQ--GEKCEFDINECKDPSNINGGCSQI--CDNTPGSYHCSCKNG 189
Query: 411 YRLDAEGARCVDRDECA-QTGRC-QAPCRNYAGGYRCDCPVG 530
+ + + C D DEC+ + C A C+N G + C+CP G
Sbjct: 190 FVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEG 231
Score = 36.7 bits (81), Expect = 0.054
Identities = 26/82 (31%), Positives = 34/82 (41%), Gaps = 5/82 (6%)
Frame = +3
Query: 306 DACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQ----TG 470
D C + C+E+G C + SF C C G+ +G +C D +EC G
Sbjct: 119 DQCSPL-PCNEDGYMS----CKDGKASFTCTCKPGW----QGEKCEFDINECKDPSNING 169
Query: 471 RCQAPCRNYAGGYRCDCPVGTV 536
C C N G Y C C G V
Sbjct: 170 GCSQICDNTPGSYHCSCKNGFV 191
>M57853-1|AAA60357.1| 676|Homo sapiens S protein protein.
Length = 676
Score = 111 bits (267), Expect = 2e-24
Identities = 56/156 (35%), Positives = 82/156 (52%), Gaps = 10/156 (6%)
Frame = +3
Query: 84 DECAVRPPPCDQ----LCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHT---CQ 239
D+C+ P PC++ C + S+ C C+ G++ G C D++EC+ ++ C
Sbjct: 119 DQCS--PLPCNEDGYMSCKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCS 172
Query: 240 QICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGY 413
QIC NT GSY CSC++G+ + C D++EC + C N+ G F C CP GY
Sbjct: 173 QICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY 232
Query: 414 RLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
R + + C D DEC++ C C NY GGY C C
Sbjct: 233 RYNLKSKSCEDIDECSE-NMCAQLCVNYPGGYTCYC 267
Score = 95.5 bits (227), Expect = 1e-19
Identities = 51/149 (34%), Positives = 75/149 (50%), Gaps = 10/149 (6%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPP-----CDQLCHNTDGSYDCLCRTGYELDEDG 188
SF C C PG++ + +EC + P C Q+C NT GSY C C+ G+ + +
Sbjct: 140 SFTCTCKPGWQ-GEKCEFDINEC--KDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNK 196
Query: 189 ANCRDVDECERDTHTC-QQICSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCPSP 359
+C+DVDEC C +C N G +EC C +G Y + +C DI+EC E +C
Sbjct: 197 KDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDEC-SENMCAQ- 254
Query: 360 GRCVNLLGSFRCVC--PRGYRLDAEGARC 440
CVN G + C C +G++L + C
Sbjct: 255 -LCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
Score = 74.5 bits (175), Expect = 2e-13
Identities = 39/116 (33%), Positives = 55/116 (47%), Gaps = 3/116 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDE 182
NT GS+ C C G+ + + DEC+++P C +C N G ++C C GY +
Sbjct: 177 NTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNL 236
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVC 350
+C D+DEC + C Q+C N G Y C C DG +K D C VC
Sbjct: 237 KSKSCEDIDECSE--NMCAQLCVNYPGGYTCYC-DG-KKGFKLAQDQKSCEVVSVC 288
Score = 64.5 bits (150), Expect = 2e-10
Identities = 35/102 (34%), Positives = 53/102 (51%), Gaps = 7/102 (6%)
Frame = +3
Query: 246 CSNTEGSYECSCEDGYEKRGDAC-VDINECHE----EGVCPSPGRCVNLLGSFRCVCPRG 410
C + + S+ C+C+ G++ G+ C DINEC + G C C N GS+ C C G
Sbjct: 134 CKDGKASFTCTCKPGWQ--GEKCEFDINECKDPSNINGGCSQI--CDNTPGSYHCSCKNG 189
Query: 411 YRLDAEGARCVDRDECA-QTGRC-QAPCRNYAGGYRCDCPVG 530
+ + + C D DEC+ + C A C+N G + C+CP G
Sbjct: 190 FVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEG 231
Score = 36.7 bits (81), Expect = 0.054
Identities = 26/82 (31%), Positives = 34/82 (41%), Gaps = 5/82 (6%)
Frame = +3
Query: 306 DACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQ----TG 470
D C + C+E+G C + SF C C G+ +G +C D +EC G
Sbjct: 119 DQCSPL-PCNEDGYMS----CKDGKASFTCTCKPGW----QGEKCEFDINECKDPSNING 169
Query: 471 RCQAPCRNYAGGYRCDCPVGTV 536
C C N G Y C C G V
Sbjct: 170 GCSQICDNTPGSYHCSCKNGFV 191
>M36564-1|AAA60180.1| 650|Homo sapiens PROS1 protein.
Length = 650
Score = 111 bits (267), Expect = 2e-24
Identities = 56/156 (35%), Positives = 82/156 (52%), Gaps = 10/156 (6%)
Frame = +3
Query: 84 DECAVRPPPCDQ----LCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHT---CQ 239
D+C+ P PC++ C + S+ C C+ G++ G C D++EC+ ++ C
Sbjct: 93 DQCS--PLPCNEDGYMSCKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCS 146
Query: 240 QICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGY 413
QIC NT GSY CSC++G+ + C D++EC + C N+ G F C CP GY
Sbjct: 147 QICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY 206
Query: 414 RLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
R + + C D DEC++ C C NY GGY C C
Sbjct: 207 RYNLKSKSCEDIDECSE-NMCAQLCVNYPGGYTCYC 241
Score = 95.5 bits (227), Expect = 1e-19
Identities = 51/149 (34%), Positives = 75/149 (50%), Gaps = 10/149 (6%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPP-----CDQLCHNTDGSYDCLCRTGYELDEDG 188
SF C C PG++ + +EC + P C Q+C NT GSY C C+ G+ + +
Sbjct: 114 SFTCTCKPGWQ-GEKCEFDINEC--KDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNK 170
Query: 189 ANCRDVDECERDTHTC-QQICSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCPSP 359
+C+DVDEC C +C N G +EC C +G Y + +C DI+EC E +C
Sbjct: 171 KDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDEC-SENMCAQ- 228
Query: 360 GRCVNLLGSFRCVC--PRGYRLDAEGARC 440
CVN G + C C +G++L + C
Sbjct: 229 -LCVNYPGGYTCYCDGKKGFKLAQDQKSC 256
Score = 74.5 bits (175), Expect = 2e-13
Identities = 39/116 (33%), Positives = 55/116 (47%), Gaps = 3/116 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDE 182
NT GS+ C C G+ + + DEC+++P C +C N G ++C C GY +
Sbjct: 151 NTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNL 210
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVC 350
+C D+DEC + C Q+C N G Y C C DG +K D C VC
Sbjct: 211 KSKSCEDIDECSE--NMCAQLCVNYPGGYTCYC-DG-KKGFKLAQDQKSCEVVSVC 262
Score = 64.5 bits (150), Expect = 2e-10
Identities = 35/102 (34%), Positives = 53/102 (51%), Gaps = 7/102 (6%)
Frame = +3
Query: 246 CSNTEGSYECSCEDGYEKRGDAC-VDINECHE----EGVCPSPGRCVNLLGSFRCVCPRG 410
C + + S+ C+C+ G++ G+ C DINEC + G C C N GS+ C C G
Sbjct: 108 CKDGKASFTCTCKPGWQ--GEKCEFDINECKDPSNINGGCSQI--CDNTPGSYHCSCKNG 163
Query: 411 YRLDAEGARCVDRDECA-QTGRC-QAPCRNYAGGYRCDCPVG 530
+ + + C D DEC+ + C A C+N G + C+CP G
Sbjct: 164 FVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEG 205
Score = 36.7 bits (81), Expect = 0.054
Identities = 26/82 (31%), Positives = 34/82 (41%), Gaps = 5/82 (6%)
Frame = +3
Query: 306 DACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQ----TG 470
D C + C+E+G C + SF C C G+ +G +C D +EC G
Sbjct: 93 DQCSPL-PCNEDGYMS----CKDGKASFTCTCKPGW----QGEKCEFDINECKDPSNING 143
Query: 471 RCQAPCRNYAGGYRCDCPVGTV 536
C C N G Y C C G V
Sbjct: 144 GCSQICDNTPGSYHCSCKNGFV 165
>M15036-1|AAA36479.1| 676|Homo sapiens protein ( Human vitamin
K-dependent plasma protein S mRNA, complete cds. ).
Length = 676
Score = 111 bits (267), Expect = 2e-24
Identities = 56/156 (35%), Positives = 82/156 (52%), Gaps = 10/156 (6%)
Frame = +3
Query: 84 DECAVRPPPCDQ----LCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHT---CQ 239
D+C+ P PC++ C + S+ C C+ G++ G C D++EC+ ++ C
Sbjct: 119 DQCS--PLPCNEDGYMSCKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCS 172
Query: 240 QICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGY 413
QIC NT GSY CSC++G+ + C D++EC + C N+ G F C CP GY
Sbjct: 173 QICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY 232
Query: 414 RLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
R + + C D DEC++ C C NY GGY C C
Sbjct: 233 RYNLKSKSCEDIDECSE-NMCAQLCVNYPGGYTCYC 267
Score = 95.5 bits (227), Expect = 1e-19
Identities = 51/149 (34%), Positives = 75/149 (50%), Gaps = 10/149 (6%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPP-----CDQLCHNTDGSYDCLCRTGYELDEDG 188
SF C C PG++ + +EC + P C Q+C NT GSY C C+ G+ + +
Sbjct: 140 SFTCTCKPGWQ-GEKCEFDINEC--KDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNK 196
Query: 189 ANCRDVDECERDTHTC-QQICSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCPSP 359
+C+DVDEC C +C N G +EC C +G Y + +C DI+EC E +C
Sbjct: 197 KDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDEC-SENMCAQ- 254
Query: 360 GRCVNLLGSFRCVC--PRGYRLDAEGARC 440
CVN G + C C +G++L + C
Sbjct: 255 -LCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
Score = 74.5 bits (175), Expect = 2e-13
Identities = 39/116 (33%), Positives = 55/116 (47%), Gaps = 3/116 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDE 182
NT GS+ C C G+ + + DEC+++P C +C N G ++C C GY +
Sbjct: 177 NTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNL 236
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVC 350
+C D+DEC + C Q+C N G Y C C DG +K D C VC
Sbjct: 237 KSKSCEDIDECSE--NMCAQLCVNYPGGYTCYC-DG-KKGFKLAQDQKSCEVVSVC 288
Score = 64.5 bits (150), Expect = 2e-10
Identities = 35/102 (34%), Positives = 53/102 (51%), Gaps = 7/102 (6%)
Frame = +3
Query: 246 CSNTEGSYECSCEDGYEKRGDAC-VDINECHE----EGVCPSPGRCVNLLGSFRCVCPRG 410
C + + S+ C+C+ G++ G+ C DINEC + G C C N GS+ C C G
Sbjct: 134 CKDGKASFTCTCKPGWQ--GEKCEFDINECKDPSNINGGCSQI--CDNTPGSYHCSCKNG 189
Query: 411 YRLDAEGARCVDRDECA-QTGRC-QAPCRNYAGGYRCDCPVG 530
+ + + C D DEC+ + C A C+N G + C+CP G
Sbjct: 190 FVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEG 231
Score = 36.7 bits (81), Expect = 0.054
Identities = 26/82 (31%), Positives = 34/82 (41%), Gaps = 5/82 (6%)
Frame = +3
Query: 306 DACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQ----TG 470
D C + C+E+G C + SF C C G+ +G +C D +EC G
Sbjct: 119 DQCSPL-PCNEDGYMS----CKDGKASFTCTCKPGW----QGEKCEFDINECKDPSNING 169
Query: 471 RCQAPCRNYAGGYRCDCPVGTV 536
C C N G Y C C G V
Sbjct: 170 GCSQICDNTPGSYHCSCKNGFV 191
>BC015801-1|AAH15801.1| 676|Homo sapiens PROS1 protein protein.
Length = 676
Score = 111 bits (267), Expect = 2e-24
Identities = 56/156 (35%), Positives = 82/156 (52%), Gaps = 10/156 (6%)
Frame = +3
Query: 84 DECAVRPPPCDQ----LCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHT---CQ 239
D+C+ P PC++ C + S+ C C+ G++ G C D++EC+ ++ C
Sbjct: 119 DQCS--PLPCNEDGYMSCKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCS 172
Query: 240 QICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGY 413
QIC NT GSY CSC++G+ + C D++EC + C N+ G F C CP GY
Sbjct: 173 QICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY 232
Query: 414 RLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
R + + C D DEC++ C C NY GGY C C
Sbjct: 233 RYNLKSKSCEDIDECSE-NMCAQLCVNYPGGYTCYC 267
Score = 95.5 bits (227), Expect = 1e-19
Identities = 51/149 (34%), Positives = 75/149 (50%), Gaps = 10/149 (6%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPP-----CDQLCHNTDGSYDCLCRTGYELDEDG 188
SF C C PG++ + +EC + P C Q+C NT GSY C C+ G+ + +
Sbjct: 140 SFTCTCKPGWQ-GEKCEFDINEC--KDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNK 196
Query: 189 ANCRDVDECERDTHTC-QQICSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCPSP 359
+C+DVDEC C +C N G +EC C +G Y + +C DI+EC E +C
Sbjct: 197 KDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDEC-SENMCAQ- 254
Query: 360 GRCVNLLGSFRCVC--PRGYRLDAEGARC 440
CVN G + C C +G++L + C
Sbjct: 255 -LCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
Score = 74.5 bits (175), Expect = 2e-13
Identities = 39/116 (33%), Positives = 55/116 (47%), Gaps = 3/116 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDE 182
NT GS+ C C G+ + + DEC+++P C +C N G ++C C GY +
Sbjct: 177 NTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNL 236
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVC 350
+C D+DEC + C Q+C N G Y C C DG +K D C VC
Sbjct: 237 KSKSCEDIDECSE--NMCAQLCVNYPGGYTCYC-DG-KKGFKLAQDQKSCEVVSVC 288
Score = 64.5 bits (150), Expect = 2e-10
Identities = 35/102 (34%), Positives = 53/102 (51%), Gaps = 7/102 (6%)
Frame = +3
Query: 246 CSNTEGSYECSCEDGYEKRGDAC-VDINECHE----EGVCPSPGRCVNLLGSFRCVCPRG 410
C + + S+ C+C+ G++ G+ C DINEC + G C C N GS+ C C G
Sbjct: 134 CKDGKASFTCTCKPGWQ--GEKCEFDINECKDPSNINGGCSQI--CDNTPGSYHCSCKNG 189
Query: 411 YRLDAEGARCVDRDECA-QTGRC-QAPCRNYAGGYRCDCPVG 530
+ + + C D DEC+ + C A C+N G + C+CP G
Sbjct: 190 FVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEG 231
Score = 36.7 bits (81), Expect = 0.054
Identities = 26/82 (31%), Positives = 34/82 (41%), Gaps = 5/82 (6%)
Frame = +3
Query: 306 DACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQ----TG 470
D C + C+E+G C + SF C C G+ +G +C D +EC G
Sbjct: 119 DQCSPL-PCNEDGYMS----CKDGKASFTCTCKPGW----QGEKCEFDINECKDPSNING 169
Query: 471 RCQAPCRNYAGGYRCDCPVGTV 536
C C N G Y C C G V
Sbjct: 170 GCSQICDNTPGSYHCSCKNGFV 191
>AY308744-1|AAP45054.1| 497|Homo sapiens protein S (alpha) protein.
Length = 497
Score = 111 bits (267), Expect = 2e-24
Identities = 56/156 (35%), Positives = 82/156 (52%), Gaps = 10/156 (6%)
Frame = +3
Query: 84 DECAVRPPPCDQ----LCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHT---CQ 239
D+C+ P PC++ C + S+ C C+ G++ G C D++EC+ ++ C
Sbjct: 119 DQCS--PLPCNEDGYMSCKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCS 172
Query: 240 QICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGY 413
QIC NT GSY CSC++G+ + C D++EC + C N+ G F C CP GY
Sbjct: 173 QICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY 232
Query: 414 RLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
R + + C D DEC++ C C NY GGY C C
Sbjct: 233 RYNLKSKSCEDIDECSE-NMCAQLCVNYPGGYTCYC 267
Score = 95.5 bits (227), Expect = 1e-19
Identities = 51/149 (34%), Positives = 75/149 (50%), Gaps = 10/149 (6%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPP-----CDQLCHNTDGSYDCLCRTGYELDEDG 188
SF C C PG++ + +EC + P C Q+C NT GSY C C+ G+ + +
Sbjct: 140 SFTCTCKPGWQ-GEKCEFDINEC--KDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNK 196
Query: 189 ANCRDVDECERDTHTC-QQICSNTEGSYECSCEDG--YEKRGDACVDINECHEEGVCPSP 359
+C+DVDEC C +C N G +EC C +G Y + +C DI+EC E +C
Sbjct: 197 KDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDEC-SENMCAQ- 254
Query: 360 GRCVNLLGSFRCVC--PRGYRLDAEGARC 440
CVN G + C C +G++L + C
Sbjct: 255 -LCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
Score = 74.5 bits (175), Expect = 2e-13
Identities = 39/116 (33%), Positives = 55/116 (47%), Gaps = 3/116 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRTGYELDE 182
NT GS+ C C G+ + + DEC+++P C +C N G ++C C GY +
Sbjct: 177 NTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNL 236
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVC 350
+C D+DEC + C Q+C N G Y C C DG +K D C VC
Sbjct: 237 KSKSCEDIDECSE--NMCAQLCVNYPGGYTCYC-DG-KKGFKLAQDQKSCEVVSVC 288
Score = 64.5 bits (150), Expect = 2e-10
Identities = 35/102 (34%), Positives = 53/102 (51%), Gaps = 7/102 (6%)
Frame = +3
Query: 246 CSNTEGSYECSCEDGYEKRGDAC-VDINECHE----EGVCPSPGRCVNLLGSFRCVCPRG 410
C + + S+ C+C+ G++ G+ C DINEC + G C C N GS+ C C G
Sbjct: 134 CKDGKASFTCTCKPGWQ--GEKCEFDINECKDPSNINGGCSQI--CDNTPGSYHCSCKNG 189
Query: 411 YRLDAEGARCVDRDECA-QTGRC-QAPCRNYAGGYRCDCPVG 530
+ + + C D DEC+ + C A C+N G + C+CP G
Sbjct: 190 FVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEG 231
Score = 36.7 bits (81), Expect = 0.054
Identities = 26/82 (31%), Positives = 34/82 (41%), Gaps = 5/82 (6%)
Frame = +3
Query: 306 DACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQ----TG 470
D C + C+E+G C + SF C C G+ +G +C D +EC G
Sbjct: 119 DQCSPL-PCNEDGYMS----CKDGKASFTCTCKPGW----QGEKCEFDINECKDPSNING 169
Query: 471 RCQAPCRNYAGGYRCDCPVGTV 536
C C N G Y C C G V
Sbjct: 170 GCSQICDNTPGSYHCSCKNGFV 191
>X81479-1|CAA57232.1| 886|Homo sapiens EMR1 protein.
Length = 886
Score = 111 bits (266), Expect = 2e-24
Identities = 65/202 (32%), Positives = 90/202 (44%), Gaps = 29/202 (14%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGR-------GVRGRD--ECAVRPPPC--DQLCHNTDGSYDCLC 158
NT+ S+ C C G+ + GVR +D EC+ P PC + C N G Y C C
Sbjct: 49 NTVDSYYCTCKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSC 108
Query: 159 RTGYELDEDGA---------NCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRG 305
G+ +C D++EC + C + C N+ GSY CSC+ G+ R
Sbjct: 109 LDGFSSPTGNDWVPGKPGNFSCTDINEC-LTSRVCPEHSDCVNSMGSYSCSCQVGFISRN 167
Query: 306 DACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGY-----RLDAEG--ARCVDRDECAQ 464
C D+NEC + CP C N +G++ C C G+ L +G A C D DEC +
Sbjct: 168 STCEDVNECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSCQGLKASCEDIDECTE 227
Query: 465 TGRCQAPCRNYAGGYRCDCPVG 530
+ C N G Y C C G
Sbjct: 228 MCPINSTCTNTPGSYFCTCHPG 249
Score = 106 bits (255), Expect = 4e-23
Identities = 66/191 (34%), Positives = 84/191 (43%), Gaps = 22/191 (11%)
Frame = +3
Query: 45 PGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGY-------ELDEDGANCRD 203
P +P +G RD P C NT SY C C+ G+ + G C+D
Sbjct: 24 PTRKPNTKGNNCRDSTLC---PAYATCTNTVDSYYCTCKQGFLSSNGQNHFKDPGVRCKD 80
Query: 204 VDECERDTHTC--QQICSNTEGSYECSCEDGYE----------KRGD-ACVDINECHEEG 344
+DEC + C C N G Y+CSC DG+ K G+ +C DINEC
Sbjct: 81 IDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSR 140
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC--QAPCRNYAGGYRCD 518
VCP CVN +GS+ C C G+ + + C D +ECA C A C N G Y C
Sbjct: 141 VCPEHSDCVNSMGSYSCSCQVGF--ISRNSTCEDVNECADPRACPEHATCNNTVGNYSCF 198
Query: 519 CPVGTVRSPSG 551
C G S SG
Sbjct: 199 CNPG-FESSSG 208
Score = 96.7 bits (230), Expect = 5e-20
Identities = 70/213 (32%), Positives = 92/213 (43%), Gaps = 33/213 (15%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR-PAGRG-VRGR---------DECAV-RPPPCDQLCHNTDGSYDCL 155
N G ++C C G+ P G V G+ +EC R P C N+ GSY C
Sbjct: 99 NLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSRVCPEHSDCVNSMGSYSCS 158
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGD------- 308
C+ G+ + C DV+EC D C + C+NT G+Y C C G+E
Sbjct: 159 CQVGFI--SRNSTCEDVNECA-DPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSCQGL 215
Query: 309 --ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDA-------EGARCVDRDECA 461
+C DI+EC E +CP C N GS+ C C G+ + +G C D DEC
Sbjct: 216 KASCEDIDECTE--MCPINSTCTNTPGSYFCTCHPGFAPSSGQLNFTDQGVECRDIDECR 273
Query: 462 QTGRCQAP---CRNYAGGYRCDCPVGTVRSPSG 551
Q P C N G Y C C VG +P G
Sbjct: 274 QDPSTCGPNSICTNALGSYSCGCIVGFHPNPEG 306
Score = 93.1 bits (221), Expect = 6e-19
Identities = 57/163 (34%), Positives = 79/163 (48%), Gaps = 20/163 (12%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECA-VRPPPCDQLCHNTDGSYDCLCRTGYE---- 173
VN++GS+ C C G+ +ECA R P C+NT G+Y C C G+E
Sbjct: 149 VNSMGSYSCSCQVGFISRNSTCEDVNECADPRACPEHATCNNTVGNYSCFCNPGFESSSG 208
Query: 174 -LDEDG--ANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEK---------RGDA 311
L G A+C D+DEC T C C+NT GSY C+C G+ +G
Sbjct: 209 HLSCQGLKASCEDIDEC---TEMCPINSTCTNTPGSYFCTCHPGFAPSSGQLNFTDQGVE 265
Query: 312 CVDINECHEE-GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGAR 437
C DI+EC ++ C C N LGS+ C C G+ + EG++
Sbjct: 266 CRDIDECRQDPSTCGPNSICTNALGSYSCGCIVGFHPNPEGSQ 308
Score = 50.4 bits (115), Expect = 4e-06
Identities = 29/88 (32%), Positives = 42/88 (47%), Gaps = 11/88 (12%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG-------RGVRGRD--ECAVRPPPC--DQLCHNTDGSYDCLC 158
NT GS+ C C PG+ P+ +GV RD EC P C + +C N GSY C C
Sbjct: 237 NTPGSYFCTCHPGFAPSSGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGC 296
Query: 159 RTGYELDEDGANCRDVDECERDTHTCQQ 242
G+ + +G+ C+R C++
Sbjct: 297 IVGFHPNPEGSQKDGNFSCQRVLFKCKE 324
>DQ217942-1|ABB70739.1| 886|Homo sapiens EGF-like module containing
mucin-like hormone receptor-like 1 protein.
Length = 886
Score = 109 bits (262), Expect = 6e-24
Identities = 67/191 (35%), Positives = 84/191 (43%), Gaps = 22/191 (11%)
Frame = +3
Query: 45 PGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGY-------ELDEDGANCRD 203
P +P +G RD P C NT SY C C+ G+ + G C+D
Sbjct: 24 PTRKPNTKGNNCRDSTLC---PAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKD 80
Query: 204 VDECERDTHTC--QQICSNTEGSYECSCEDGYE----------KRGD-ACVDINECHEEG 344
+DEC + C C N G Y+CSC DG+ K G+ +C DINEC
Sbjct: 81 IDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSS 140
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC--QAPCRNYAGGYRCD 518
VCP CVN +GS+ C C G+ + + C D DECA C A C N G Y C
Sbjct: 141 VCPEHSDCVNSMGSYSCSCQVGF--ISRNSTCEDVDECADPRACPEHATCNNTVGNYSCF 198
Query: 519 CPVGTVRSPSG 551
C G S SG
Sbjct: 199 CNPG-FESSSG 208
Score = 107 bits (258), Expect = 2e-23
Identities = 64/202 (31%), Positives = 90/202 (44%), Gaps = 29/202 (14%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGR-------GVRGRD--ECAVRPPPC--DQLCHNTDGSYDCLC 158
NT+ S+ C C G+ + GVR +D EC+ P PC + C N G Y C C
Sbjct: 49 NTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSC 108
Query: 159 RTGYELDEDGA---------NCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRG 305
G+ +C D++EC + C + C N+ GSY CSC+ G+ R
Sbjct: 109 LDGFSSPTGNDWVPGKPGNFSCTDINECLTSS-VCPEHSDCVNSMGSYSCSCQVGFISRN 167
Query: 306 DACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGY-----RLDAEG--ARCVDRDECAQ 464
C D++EC + CP C N +G++ C C G+ L +G A C D DEC +
Sbjct: 168 STCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTE 227
Query: 465 TGRCQAPCRNYAGGYRCDCPVG 530
+ C N G Y C C G
Sbjct: 228 MCPINSTCTNTPGSYFCTCHPG 249
Score = 96.3 bits (229), Expect = 6e-20
Identities = 58/163 (35%), Positives = 79/163 (48%), Gaps = 20/163 (12%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECA-VRPPPCDQLCHNTDGSYDCLCRTGYE---- 173
VN++GS+ C C G+ DECA R P C+NT G+Y C C G+E
Sbjct: 149 VNSMGSYSCSCQVGFISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSG 208
Query: 174 -LDEDG--ANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEK---------RGDA 311
L G A+C D+DEC T C C+NT GSY C+C G+ +G
Sbjct: 209 HLSFQGLKASCEDIDEC---TEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVE 265
Query: 312 CVDINECHEE-GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGAR 437
C DI+EC ++ C C N LGS+ C C G+ + EG++
Sbjct: 266 CRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQ 308
Score = 95.9 bits (228), Expect = 8e-20
Identities = 71/215 (33%), Positives = 92/215 (42%), Gaps = 35/215 (16%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR-PAGRG-VRGR---------DEC---AVRPPPCDQLCHNTDGSYD 149
N G ++C C G+ P G V G+ +EC +V P D C N+ GSY
Sbjct: 99 NLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSD--CVNSMGSYS 156
Query: 150 CLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGD----- 308
C C+ G+ + C DVDEC D C + C+NT G+Y C C G+E
Sbjct: 157 CSCQVGFI--SRNSTCEDVDECA-DPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQ 213
Query: 309 ----ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGY-------RLDAEGARCVDRDE 455
+C DI+EC E +CP C N GS+ C C G+ +G C D DE
Sbjct: 214 GLKASCEDIDECTE--MCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDE 271
Query: 456 CAQTGRCQAP---CRNYAGGYRCDCPVGTVRSPSG 551
C Q P C N G Y C C G +P G
Sbjct: 272 CRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEG 306
Score = 50.4 bits (115), Expect = 4e-06
Identities = 29/88 (32%), Positives = 42/88 (47%), Gaps = 11/88 (12%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG-------RGVRGRD--ECAVRPPPC--DQLCHNTDGSYDCLC 158
NT GS+ C C PG+ P+ +GV RD EC P C + +C N GSY C C
Sbjct: 237 NTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGC 296
Query: 159 RTGYELDEDGANCRDVDECERDTHTCQQ 242
G+ + +G+ C+R C++
Sbjct: 297 IAGFHPNPEGSQKDGNFSCQRVLFKCKE 324
>BC059395-1|AAH59395.1| 821|Homo sapiens EMR1 protein protein.
Length = 821
Score = 109 bits (262), Expect = 6e-24
Identities = 67/191 (35%), Positives = 84/191 (43%), Gaps = 22/191 (11%)
Frame = +3
Query: 45 PGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGY-------ELDEDGANCRD 203
P +P +G RD P C NT SY C C+ G+ + G C+D
Sbjct: 24 PTRKPNTKGNNCRDSTLC---PAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKD 80
Query: 204 VDECERDTHTC--QQICSNTEGSYECSCEDGYE----------KRGD-ACVDINECHEEG 344
+DEC + C C N G Y+CSC DG+ K G+ +C DINEC
Sbjct: 81 IDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSS 140
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC--QAPCRNYAGGYRCD 518
VCP CVN +GS+ C C G+ + + C D DECA C A C N G Y C
Sbjct: 141 VCPEHSDCVNSMGSYSCSCQVGF--ISRNSTCEDVDECADPRACPEHATCNNTVGNYSCF 198
Query: 519 CPVGTVRSPSG 551
C G S SG
Sbjct: 199 CNPG-FESSSG 208
Score = 107 bits (258), Expect = 2e-23
Identities = 64/202 (31%), Positives = 90/202 (44%), Gaps = 29/202 (14%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGR-------GVRGRD--ECAVRPPPC--DQLCHNTDGSYDCLC 158
NT+ S+ C C G+ + GVR +D EC+ P PC + C N G Y C C
Sbjct: 49 NTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSC 108
Query: 159 RTGYELDEDGA---------NCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRG 305
G+ +C D++EC + C + C N+ GSY CSC+ G+ R
Sbjct: 109 LDGFSSPTGNDWVPGKPGNFSCTDINECLTSS-VCPEHSDCVNSMGSYSCSCQVGFISRN 167
Query: 306 DACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGY-----RLDAEG--ARCVDRDECAQ 464
C D++EC + CP C N +G++ C C G+ L +G A C D DEC +
Sbjct: 168 STCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTE 227
Query: 465 TGRCQAPCRNYAGGYRCDCPVG 530
+ C N G Y C C G
Sbjct: 228 MCPINSTCTNTPGSYFCTCHPG 249
Score = 96.3 bits (229), Expect = 6e-20
Identities = 58/163 (35%), Positives = 79/163 (48%), Gaps = 20/163 (12%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECA-VRPPPCDQLCHNTDGSYDCLCRTGYE---- 173
VN++GS+ C C G+ DECA R P C+NT G+Y C C G+E
Sbjct: 149 VNSMGSYSCSCQVGFISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSG 208
Query: 174 -LDEDG--ANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEK---------RGDA 311
L G A+C D+DEC T C C+NT GSY C+C G+ +G
Sbjct: 209 HLSFQGLKASCEDIDEC---TEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVE 265
Query: 312 CVDINECHEE-GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGAR 437
C DI+EC ++ C C N LGS+ C C G+ + EG++
Sbjct: 266 CRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQ 308
Score = 95.9 bits (228), Expect = 8e-20
Identities = 71/215 (33%), Positives = 92/215 (42%), Gaps = 35/215 (16%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR-PAGRG-VRGR---------DEC---AVRPPPCDQLCHNTDGSYD 149
N G ++C C G+ P G V G+ +EC +V P D C N+ GSY
Sbjct: 99 NLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSD--CVNSMGSYS 156
Query: 150 CLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGD----- 308
C C+ G+ + C DVDEC D C + C+NT G+Y C C G+E
Sbjct: 157 CSCQVGFI--SRNSTCEDVDECA-DPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQ 213
Query: 309 ----ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGY-------RLDAEGARCVDRDE 455
+C DI+EC E +CP C N GS+ C C G+ +G C D DE
Sbjct: 214 GLKASCEDIDECTE--MCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDE 271
Query: 456 CAQTGRCQAP---CRNYAGGYRCDCPVGTVRSPSG 551
C Q P C N G Y C C G +P G
Sbjct: 272 CRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEG 306
Score = 50.4 bits (115), Expect = 4e-06
Identities = 29/88 (32%), Positives = 42/88 (47%), Gaps = 11/88 (12%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG-------RGVRGRD--ECAVRPPPC--DQLCHNTDGSYDCLC 158
NT GS+ C C PG+ P+ +GV RD EC P C + +C N GSY C C
Sbjct: 237 NTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGC 296
Query: 159 RTGYELDEDGANCRDVDECERDTHTCQQ 242
G+ + +G+ C+R C++
Sbjct: 297 IAGFHPNPEGSQKDGNFSCQRVLFKCKE 324
>BC038587-1|AAH38587.1| 553|Homo sapiens EGF-like-domain, multiple
6 protein.
Length = 553
Score = 109 bits (262), Expect = 6e-24
Identities = 64/181 (35%), Positives = 87/181 (48%), Gaps = 10/181 (5%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGV-RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
+G +C C PGY G+ + +EC ++P PC C NT GSY C C +G+ L D A
Sbjct: 75 VGPNKCRCFPGY--TGKTCSQDVNECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPD-AT 131
Query: 195 CRDVDECERDTHTCQQICSNTEGSYECSCEDG---YEKRGDACVDINECHE-EGVCPSPG 362
C + C CQ C +TE +C C G C+DI+EC + +CP
Sbjct: 132 CVNSRTCA--MINCQYSCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNR 189
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGAR--CVDRDEC---AQTGRCQAPCRNYAGGYRCDCPV 527
RCVN GS+ C C G+ L R C+D +EC + T A C N G ++C C
Sbjct: 190 RCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQ 249
Query: 528 G 530
G
Sbjct: 250 G 250
Score = 96.3 bits (229), Expect = 6e-20
Identities = 58/156 (37%), Positives = 77/156 (49%), Gaps = 10/156 (6%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLC-RTGYE 173
R VNT GS++C C G+ P V R CA+ C C +T+ CLC +G
Sbjct: 108 RCVNTHGSYKCFCLSGHMLMPDATCVNSRT-CAMIN--CQYSCEDTEEGPQCLCPSSGLR 164
Query: 174 LDEDGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGDA----CVDINECH 335
L +G +C D+DEC C + C NT GSY C C G+E + + C+DINEC
Sbjct: 165 LAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECT 224
Query: 336 EEG-VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC 440
+ C C N GSF+C C +GY+ G RC
Sbjct: 225 MDSHTCSHHANCFNTQGSFKCKCKQGYK--GNGLRC 258
Score = 82.2 bits (194), Expect = 1e-15
Identities = 47/120 (39%), Positives = 63/120 (52%), Gaps = 9/120 (7%)
Frame = +3
Query: 30 RCVC-GPGYR--PAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGA- 191
+C+C G R P GR DECA C ++ C NT GSY C C G+EL
Sbjct: 155 QCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGR 214
Query: 192 -NCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPG 362
+C D++EC D+HTC C NT+GS++C C+ GY+ G C I E + V +PG
Sbjct: 215 YDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRCSAIPENSVKEVLRAPG 274
Score = 63.3 bits (147), Expect = 5e-10
Identities = 43/113 (38%), Positives = 57/113 (50%), Gaps = 6/113 (5%)
Frame = +3
Query: 231 TCQQICSNTE--GSYECSCEDGYEKRGDACV-DINECHEEGVCPSP--GRCVNLLGSFRC 395
TC+ C E G +C C GY G C D+NEC G+ P P RCVN GS++C
Sbjct: 64 TCEPGCKFGECVGPNKCRCFPGYT--GKTCSQDVNEC---GMKPRPCQHRCVNTHGSYKC 118
Query: 396 VCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVR-SPSG 551
C G+ L + A CV+ CA CQ C + G +C CP +R +P+G
Sbjct: 119 FCLSGHMLMPD-ATCVNSRTCAMIN-CQYSCEDTEEGPQCLCPSSGLRLAPNG 169
Score = 33.9 bits (74), Expect = 0.38
Identities = 26/77 (33%), Positives = 35/77 (45%), Gaps = 6/77 (7%)
Frame = +3
Query: 333 HEEGVCPS---PG-RCVNLLGSFRCVCPRGYRLDAEGARCV-DRDECAQTGR-CQAPCRN 494
+ +GVC + PG + +G +C C GY G C D +EC R CQ C N
Sbjct: 56 NSKGVCEATCEPGCKFGECVGPNKCRCFPGYT----GKTCSQDVNECGMKPRPCQHRCVN 111
Query: 495 YAGGYRCDCPVGTVRSP 545
G Y+C C G + P
Sbjct: 112 THGSYKCFCLSGHMLMP 128
>AY358333-1|AAQ88699.1| 338|Homo sapiens EGFL6 protein.
Length = 338
Score = 109 bits (262), Expect = 6e-24
Identities = 64/181 (35%), Positives = 87/181 (48%), Gaps = 10/181 (5%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGV-RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
+G +C C PGY G+ + +EC ++P PC C NT GSY C C +G+ L D A
Sbjct: 75 VGPNKCRCFPGY--TGKTCSQDVNECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPD-AT 131
Query: 195 CRDVDECERDTHTCQQICSNTEGSYECSCEDG---YEKRGDACVDINECHE-EGVCPSPG 362
C + C CQ C +TE +C C G C+DI+EC + +CP
Sbjct: 132 CVNSRTCA--MINCQYSCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNR 189
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGAR--CVDRDEC---AQTGRCQAPCRNYAGGYRCDCPV 527
RCVN GS+ C C G+ L R C+D +EC + T A C N G ++C C
Sbjct: 190 RCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQ 249
Query: 528 G 530
G
Sbjct: 250 G 250
Score = 96.3 bits (229), Expect = 6e-20
Identities = 58/156 (37%), Positives = 77/156 (49%), Gaps = 10/156 (6%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLC-RTGYE 173
R VNT GS++C C G+ P V R CA+ C C +T+ CLC +G
Sbjct: 108 RCVNTHGSYKCFCLSGHMLMPDATCVNSRT-CAMIN--CQYSCEDTEEGPQCLCPSSGLR 164
Query: 174 LDEDGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGDA----CVDINECH 335
L +G +C D+DEC C + C NT GSY C C G+E + + C+DINEC
Sbjct: 165 LAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECT 224
Query: 336 EEG-VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC 440
+ C C N GSF+C C +GY+ G RC
Sbjct: 225 MDSHTCSHHANCFNTQGSFKCKCKQGYK--GNGLRC 258
Score = 82.2 bits (194), Expect = 1e-15
Identities = 47/120 (39%), Positives = 63/120 (52%), Gaps = 9/120 (7%)
Frame = +3
Query: 30 RCVC-GPGYR--PAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGA- 191
+C+C G R P GR DECA C ++ C NT GSY C C G+EL
Sbjct: 155 QCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGR 214
Query: 192 -NCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPG 362
+C D++EC D+HTC C NT+GS++C C+ GY+ G C I E + V +PG
Sbjct: 215 YDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRCSAIPENSVKEVLRAPG 274
Score = 63.3 bits (147), Expect = 5e-10
Identities = 43/113 (38%), Positives = 57/113 (50%), Gaps = 6/113 (5%)
Frame = +3
Query: 231 TCQQICSNTE--GSYECSCEDGYEKRGDACV-DINECHEEGVCPSP--GRCVNLLGSFRC 395
TC+ C E G +C C GY G C D+NEC G+ P P RCVN GS++C
Sbjct: 64 TCEPGCKFGECVGPNKCRCFPGYT--GKTCSQDVNEC---GMKPRPCQHRCVNTHGSYKC 118
Query: 396 VCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVR-SPSG 551
C G+ L + A CV+ CA CQ C + G +C CP +R +P+G
Sbjct: 119 FCLSGHMLMPD-ATCVNSRTCAMIN-CQYSCEDTEEGPQCLCPSSGLRLAPNG 169
Score = 33.9 bits (74), Expect = 0.38
Identities = 26/77 (33%), Positives = 35/77 (45%), Gaps = 6/77 (7%)
Frame = +3
Query: 333 HEEGVCPS---PG-RCVNLLGSFRCVCPRGYRLDAEGARCV-DRDECAQTGR-CQAPCRN 494
+ +GVC + PG + +G +C C GY G C D +EC R CQ C N
Sbjct: 56 NSKGVCEATCEPGCKFGECVGPNKCRCFPGYT----GKTCSQDVNECGMKPRPCQHRCVN 111
Query: 495 YAGGYRCDCPVGTVRSP 545
G Y+C C G + P
Sbjct: 112 THGSYKCFCLSGHMLMP 128
>AK075214-1|BAC11477.1| 553|Homo sapiens protein ( Homo sapiens
cDNA FLJ90733 fis, clone PLACE1010251, highly similar to
Epidermal growth factor-like protein 6 precursor. ).
Length = 553
Score = 109 bits (262), Expect = 6e-24
Identities = 64/181 (35%), Positives = 87/181 (48%), Gaps = 10/181 (5%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGV-RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
+G +C C PGY G+ + +EC ++P PC C NT GSY C C +G+ L D A
Sbjct: 75 VGPNKCRCFPGY--TGKTCSQDVNECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPD-AT 131
Query: 195 CRDVDECERDTHTCQQICSNTEGSYECSCEDG---YEKRGDACVDINECHE-EGVCPSPG 362
C + C CQ C +TE +C C G C+DI+EC + +CP
Sbjct: 132 CVNSRTCA--MINCQYSCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNR 189
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGAR--CVDRDEC---AQTGRCQAPCRNYAGGYRCDCPV 527
RCVN GS+ C C G+ L R C+D +EC + T A C N G ++C C
Sbjct: 190 RCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQ 249
Query: 528 G 530
G
Sbjct: 250 G 250
Score = 96.3 bits (229), Expect = 6e-20
Identities = 58/156 (37%), Positives = 77/156 (49%), Gaps = 10/156 (6%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLC-RTGYE 173
R VNT GS++C C G+ P V R CA+ C C +T+ CLC +G
Sbjct: 108 RCVNTHGSYKCFCLSGHMLMPDATCVNSRT-CAMIN--CQYSCEDTEEGPQCLCPSSGLR 164
Query: 174 LDEDGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGDA----CVDINECH 335
L +G +C D+DEC C + C NT GSY C C G+E + + C+DINEC
Sbjct: 165 LAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECT 224
Query: 336 EEG-VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC 440
+ C C N GSF+C C +GY+ G RC
Sbjct: 225 MDSHTCSHHANCFNTQGSFKCKCKQGYK--GNGLRC 258
Score = 82.2 bits (194), Expect = 1e-15
Identities = 47/120 (39%), Positives = 63/120 (52%), Gaps = 9/120 (7%)
Frame = +3
Query: 30 RCVC-GPGYR--PAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGA- 191
+C+C G R P GR DECA C ++ C NT GSY C C G+EL
Sbjct: 155 QCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGR 214
Query: 192 -NCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPG 362
+C D++EC D+HTC C NT+GS++C C+ GY+ G C I E + V +PG
Sbjct: 215 YDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRCSAIPENSVKEVLRAPG 274
Score = 63.3 bits (147), Expect = 5e-10
Identities = 43/113 (38%), Positives = 57/113 (50%), Gaps = 6/113 (5%)
Frame = +3
Query: 231 TCQQICSNTE--GSYECSCEDGYEKRGDACV-DINECHEEGVCPSP--GRCVNLLGSFRC 395
TC+ C E G +C C GY G C D+NEC G+ P P RCVN GS++C
Sbjct: 64 TCEPGCKFGECVGPNKCRCFPGYT--GKTCSQDVNEC---GMKPRPCQHRCVNTHGSYKC 118
Query: 396 VCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVR-SPSG 551
C G+ L + A CV+ CA CQ C + G +C CP +R +P+G
Sbjct: 119 FCLSGHMLMPD-ATCVNSRTCAMIN-CQYSCEDTEEGPQCLCPSSGLRLAPNG 169
Score = 33.9 bits (74), Expect = 0.38
Identities = 26/77 (33%), Positives = 35/77 (45%), Gaps = 6/77 (7%)
Frame = +3
Query: 333 HEEGVCPS---PG-RCVNLLGSFRCVCPRGYRLDAEGARCV-DRDECAQTGR-CQAPCRN 494
+ +GVC + PG + +G +C C GY G C D +EC R CQ C N
Sbjct: 56 NSKGVCEATCEPGCKFGECVGPNKCRCFPGYT----GKTCSQDVNECGMKPRPCQHRCVN 111
Query: 495 YAGGYRCDCPVGTVRSP 545
G Y+C C G + P
Sbjct: 112 THGSYKCFCLSGHMLMP 128
>AJ245671-1|CAB92132.1| 554|Homo sapiens hypothetical protein
protein.
Length = 554
Score = 109 bits (262), Expect = 6e-24
Identities = 64/181 (35%), Positives = 87/181 (48%), Gaps = 10/181 (5%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGV-RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
+G +C C PGY G+ + +EC ++P PC C NT GSY C C +G+ L D A
Sbjct: 75 VGPNKCRCFPGY--TGKTCSQDVNECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPD-AT 131
Query: 195 CRDVDECERDTHTCQQICSNTEGSYECSCEDG---YEKRGDACVDINECHE-EGVCPSPG 362
C + C CQ C +TE +C C G C+DI+EC + +CP
Sbjct: 132 CVNSRTCA--MINCQYSCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNR 189
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGAR--CVDRDEC---AQTGRCQAPCRNYAGGYRCDCPV 527
RCVN GS+ C C G+ L R C+D +EC + T A C N G ++C C
Sbjct: 190 RCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQ 249
Query: 528 G 530
G
Sbjct: 250 G 250
Score = 96.3 bits (229), Expect = 6e-20
Identities = 58/156 (37%), Positives = 77/156 (49%), Gaps = 10/156 (6%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLC-RTGYE 173
R VNT GS++C C G+ P V R CA+ C C +T+ CLC +G
Sbjct: 108 RCVNTHGSYKCFCLSGHMLMPDATCVNSRT-CAMIN--CQYSCEDTEEGPQCLCPSSGLR 164
Query: 174 LDEDGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGDA----CVDINECH 335
L +G +C D+DEC C + C NT GSY C C G+E + + C+DINEC
Sbjct: 165 LAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECT 224
Query: 336 EEG-VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC 440
+ C C N GSF+C C +GY+ G RC
Sbjct: 225 MDSHTCSHHANCFNTQGSFKCKCKQGYK--GNGLRC 258
Score = 82.2 bits (194), Expect = 1e-15
Identities = 47/120 (39%), Positives = 63/120 (52%), Gaps = 9/120 (7%)
Frame = +3
Query: 30 RCVC-GPGYR--PAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGA- 191
+C+C G R P GR DECA C ++ C NT GSY C C G+EL
Sbjct: 155 QCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGR 214
Query: 192 -NCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPG 362
+C D++EC D+HTC C NT+GS++C C+ GY+ G C I E + V +PG
Sbjct: 215 YDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRCSAIPENSVKEVLRAPG 274
Score = 63.3 bits (147), Expect = 5e-10
Identities = 43/113 (38%), Positives = 57/113 (50%), Gaps = 6/113 (5%)
Frame = +3
Query: 231 TCQQICSNTE--GSYECSCEDGYEKRGDACV-DINECHEEGVCPSP--GRCVNLLGSFRC 395
TC+ C E G +C C GY G C D+NEC G+ P P RCVN GS++C
Sbjct: 64 TCEPGCKFGECVGPNKCRCFPGYT--GKTCSQDVNEC---GMKPRPCQHRCVNTHGSYKC 118
Query: 396 VCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVR-SPSG 551
C G+ L + A CV+ CA CQ C + G +C CP +R +P+G
Sbjct: 119 FCLSGHMLMPD-ATCVNSRTCAMIN-CQYSCEDTEEGPQCLCPSSGLRLAPNG 169
Score = 33.9 bits (74), Expect = 0.38
Identities = 26/77 (33%), Positives = 35/77 (45%), Gaps = 6/77 (7%)
Frame = +3
Query: 333 HEEGVCPS---PG-RCVNLLGSFRCVCPRGYRLDAEGARCV-DRDECAQTGR-CQAPCRN 494
+ +GVC + PG + +G +C C GY G C D +EC R CQ C N
Sbjct: 56 NSKGVCEATCEPGCKFGECVGPNKCRCFPGYT----GKTCSQDVNECGMKPRPCQHRCVN 111
Query: 495 YAGGYRCDCPVGTVRSP 545
G Y+C C G + P
Sbjct: 112 THGSYKCFCLSGHMLMP 128
>AF186084-1|AAF27812.1| 553|Homo sapiens epidermal growth factor
repeat containing protein protein.
Length = 553
Score = 109 bits (262), Expect = 6e-24
Identities = 64/181 (35%), Positives = 87/181 (48%), Gaps = 10/181 (5%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGV-RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
+G +C C PGY G+ + +EC ++P PC C NT GSY C C +G+ L D A
Sbjct: 75 VGPNKCRCFPGY--TGKTCSQDVNECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPD-AT 131
Query: 195 CRDVDECERDTHTCQQICSNTEGSYECSCEDG---YEKRGDACVDINECHE-EGVCPSPG 362
C + C CQ C +TE +C C G C+DI+EC + +CP
Sbjct: 132 CVNSRTCA--MINCQYSCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNR 189
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGAR--CVDRDEC---AQTGRCQAPCRNYAGGYRCDCPV 527
RCVN GS+ C C G+ L R C+D +EC + T A C N G ++C C
Sbjct: 190 RCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQ 249
Query: 528 G 530
G
Sbjct: 250 G 250
Score = 96.3 bits (229), Expect = 6e-20
Identities = 58/156 (37%), Positives = 77/156 (49%), Gaps = 10/156 (6%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLC-RTGYE 173
R VNT GS++C C G+ P V R CA+ C C +T+ CLC +G
Sbjct: 108 RCVNTHGSYKCFCLSGHMLMPDATCVNSRT-CAMIN--CQYSCEDTEEGPQCLCPSSGLR 164
Query: 174 LDEDGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGDA----CVDINECH 335
L +G +C D+DEC C + C NT GSY C C G+E + + C+DINEC
Sbjct: 165 LAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECT 224
Query: 336 EEG-VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC 440
+ C C N GSF+C C +GY+ G RC
Sbjct: 225 MDSHTCSHHANCFNTQGSFKCKCKQGYK--GNGLRC 258
Score = 82.2 bits (194), Expect = 1e-15
Identities = 47/120 (39%), Positives = 63/120 (52%), Gaps = 9/120 (7%)
Frame = +3
Query: 30 RCVC-GPGYR--PAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGA- 191
+C+C G R P GR DECA C ++ C NT GSY C C G+EL
Sbjct: 155 QCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGR 214
Query: 192 -NCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPG 362
+C D++EC D+HTC C NT+GS++C C+ GY+ G C I E + V +PG
Sbjct: 215 YDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRCSAIPENSVKEVLRAPG 274
Score = 63.3 bits (147), Expect = 5e-10
Identities = 43/113 (38%), Positives = 57/113 (50%), Gaps = 6/113 (5%)
Frame = +3
Query: 231 TCQQICSNTE--GSYECSCEDGYEKRGDACV-DINECHEEGVCPSP--GRCVNLLGSFRC 395
TC+ C E G +C C GY G C D+NEC G+ P P RCVN GS++C
Sbjct: 64 TCEPGCKFGECVGPNKCRCFPGYT--GKTCSQDVNEC---GMKPRPCQHRCVNTHGSYKC 118
Query: 396 VCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVR-SPSG 551
C G+ L + A CV+ CA CQ C + G +C CP +R +P+G
Sbjct: 119 FCLSGHMLMPD-ATCVNSRTCAMIN-CQYSCEDTEEGPQCLCPSSGLRLAPNG 169
Score = 33.9 bits (74), Expect = 0.38
Identities = 26/77 (33%), Positives = 35/77 (45%), Gaps = 6/77 (7%)
Frame = +3
Query: 333 HEEGVCPS---PG-RCVNLLGSFRCVCPRGYRLDAEGARCV-DRDECAQTGR-CQAPCRN 494
+ +GVC + PG + +G +C C GY G C D +EC R CQ C N
Sbjct: 56 NSKGVCEATCEPGCKFGECVGPNKCRCFPGYT----GKTCSQDVNECGMKPRPCQHRCVN 111
Query: 495 YAGGYRCDCPVGTVRSP 545
G Y+C C G + P
Sbjct: 112 THGSYKCFCLSGHMLMP 128
>AB065918-1|BAC06133.1| 929|Homo sapiens seven transmembrane helix
receptor protein.
Length = 929
Score = 109 bits (262), Expect = 6e-24
Identities = 67/191 (35%), Positives = 84/191 (43%), Gaps = 22/191 (11%)
Frame = +3
Query: 45 PGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGY-------ELDEDGANCRD 203
P +P +G RD P C NT SY C C+ G+ + G C+D
Sbjct: 42 PTRKPNTKGNNCRDSTLC---PAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKD 98
Query: 204 VDECERDTHTC--QQICSNTEGSYECSCEDGYE----------KRGD-ACVDINECHEEG 344
+DEC + C C N G Y+CSC DG+ K G+ +C DINEC
Sbjct: 99 IDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSS 158
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC--QAPCRNYAGGYRCD 518
VCP CVN +GS+ C C G+ + + C D DECA C A C N G Y C
Sbjct: 159 VCPEHSDCVNSMGSYSCSCQVGF--ISRNSTCEDVDECADPRACPEHATCNNTVGNYSCF 216
Query: 519 CPVGTVRSPSG 551
C G S SG
Sbjct: 217 CNPG-FESSSG 226
Score = 107 bits (258), Expect = 2e-23
Identities = 64/202 (31%), Positives = 90/202 (44%), Gaps = 29/202 (14%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGR-------GVRGRD--ECAVRPPPC--DQLCHNTDGSYDCLC 158
NT+ S+ C C G+ + GVR +D EC+ P PC + C N G Y C C
Sbjct: 67 NTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSC 126
Query: 159 RTGYELDEDGA---------NCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRG 305
G+ +C D++EC + C + C N+ GSY CSC+ G+ R
Sbjct: 127 LDGFSSPTGNDWVPGKPGNFSCTDINECLTSS-VCPEHSDCVNSMGSYSCSCQVGFISRN 185
Query: 306 DACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGY-----RLDAEG--ARCVDRDECAQ 464
C D++EC + CP C N +G++ C C G+ L +G A C D DEC +
Sbjct: 186 STCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTE 245
Query: 465 TGRCQAPCRNYAGGYRCDCPVG 530
+ C N G Y C C G
Sbjct: 246 MCPINSTCTNTPGSYFCTCHPG 267
Score = 96.3 bits (229), Expect = 6e-20
Identities = 58/163 (35%), Positives = 79/163 (48%), Gaps = 20/163 (12%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECA-VRPPPCDQLCHNTDGSYDCLCRTGYE---- 173
VN++GS+ C C G+ DECA R P C+NT G+Y C C G+E
Sbjct: 167 VNSMGSYSCSCQVGFISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSG 226
Query: 174 -LDEDG--ANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEK---------RGDA 311
L G A+C D+DEC T C C+NT GSY C+C G+ +G
Sbjct: 227 HLSFQGLKASCEDIDEC---TEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVE 283
Query: 312 CVDINECHEE-GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGAR 437
C DI+EC ++ C C N LGS+ C C G+ + EG++
Sbjct: 284 CRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQ 326
Score = 95.9 bits (228), Expect = 8e-20
Identities = 71/215 (33%), Positives = 92/215 (42%), Gaps = 35/215 (16%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR-PAGRG-VRGR---------DEC---AVRPPPCDQLCHNTDGSYD 149
N G ++C C G+ P G V G+ +EC +V P D C N+ GSY
Sbjct: 117 NLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSD--CVNSMGSYS 174
Query: 150 CLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGD----- 308
C C+ G+ + C DVDEC D C + C+NT G+Y C C G+E
Sbjct: 175 CSCQVGFI--SRNSTCEDVDECA-DPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQ 231
Query: 309 ----ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGY-------RLDAEGARCVDRDE 455
+C DI+EC E +CP C N GS+ C C G+ +G C D DE
Sbjct: 232 GLKASCEDIDECTE--MCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDE 289
Query: 456 CAQTGRCQAP---CRNYAGGYRCDCPVGTVRSPSG 551
C Q P C N G Y C C G +P G
Sbjct: 290 CRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEG 324
Score = 50.4 bits (115), Expect = 4e-06
Identities = 29/88 (32%), Positives = 42/88 (47%), Gaps = 11/88 (12%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG-------RGVRGRD--ECAVRPPPC--DQLCHNTDGSYDCLC 158
NT GS+ C C PG+ P+ +GV RD EC P C + +C N GSY C C
Sbjct: 255 NTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGC 314
Query: 159 RTGYELDEDGANCRDVDECERDTHTCQQ 242
G+ + +G+ C+R C++
Sbjct: 315 IAGFHPNPEGSQKDGNFSCQRVLFKCKE 342
>AK027775-1|BAB55358.1| 537|Homo sapiens protein ( Homo sapiens
cDNA FLJ14869 fis, clone PLACE1002474, moderately
similar to Mus musculus matrilin-2 precursor mRNA. ).
Length = 537
Score = 108 bits (259), Expect = 1e-23
Identities = 60/174 (34%), Positives = 81/174 (46%), Gaps = 5/174 (2%)
Frame = +3
Query: 24 SFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
S+ C C GY P G+ D CA + C+QLC NT+ S+ C C G+ ++ED C
Sbjct: 4 SYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLMTC 63
Query: 198 RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCV 371
VD C H C+ C N + S+ C C +G+ R D C ++ C G CV
Sbjct: 64 SRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSC-ALGDHGCEHSCV 122
Query: 372 NLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQAPCRNYAGGYRCDCPVG 530
+ SF C C GY L +G C +D C A C+ C N Y C+C G
Sbjct: 123 SSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEG 176
Score = 107 bits (256), Expect = 3e-23
Identities = 61/189 (32%), Positives = 81/189 (42%), Gaps = 8/189 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+NT SF C C G+ D C + C+ C N D S+ C C G+ L
Sbjct: 40 LNTEDSFVCQCSEGFLINEDLMTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRS 99
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPG 362
DG C +D C H C+ C ++E S+ C C +GY R D C + VC +
Sbjct: 100 DGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDG----KTCRRKDVCQAID 155
Query: 363 R-----CVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQAPCRNYAGGYRCDCP 524
CVN S+ C C G+RL +G RC +D C T C+ C N Y C C
Sbjct: 156 HGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCS 215
Query: 525 VGTVRSPSG 551
G V + G
Sbjct: 216 EGFVLAEDG 224
Score = 99.1 bits (236), Expect = 9e-21
Identities = 53/151 (35%), Positives = 71/151 (47%), Gaps = 7/151 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN SF C C G+ R G+ D CA+ C+ C +++ S+ C C GY L E
Sbjct: 81 VNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILRE 140
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPG 362
DG CR D C+ H C+ IC N++ SY C C +G+ D C + VC S
Sbjct: 141 DGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDG----KRCRRKDVCKSTH 196
Query: 363 R-----CVNLLGSFRCVCPRGYRLDAEGARC 440
CVN S+ C C G+ L +G RC
Sbjct: 197 HGCEHICVNNGNSYICKCSEGFVLAEDGRRC 227
Score = 53.6 bits (123), Expect = 4e-07
Identities = 26/70 (37%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN+ S+ C C G+R A G+ R +D C C+ +C N SY C C G+ L E
Sbjct: 163 VNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAE 222
Query: 183 DGANCRDVDE 212
DG C+ E
Sbjct: 223 DGRRCKKCTE 232
>BC127263-1|AAI27264.1| 363|Homo sapiens SCUBE1 protein protein.
Length = 363
Score = 107 bits (258), Expect = 2e-23
Identities = 64/177 (36%), Positives = 83/177 (46%), Gaps = 16/177 (9%)
Frame = +3
Query: 48 GYRPAGRGVRGR---DECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDE 212
G G G+ G DEC+ C D +C NT SY CLC+ GY+ +G C D+DE
Sbjct: 20 GRLAGGSGLPGSVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYK--GEGKQCEDIDE 77
Query: 213 CERDTHT--CQQICSNTEGSYECSCEDGY--EKRGDACVDINECHE-EGVCPSPGRCVNL 377
CE D + C C N G+Y C+C DG+ G C+D++EC + G C CVN
Sbjct: 78 CENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ--ICVNA 135
Query: 378 LGSFRCVCPRGYRLDAEGARCVDRD----ECAQTGR-CQAPCRNY-AGGYRCDCPVG 530
+GS+ C C G+ L C+ R C C CR GG CDC G
Sbjct: 136 MGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPG 192
Score = 104 bits (249), Expect = 2e-22
Identities = 60/178 (33%), Positives = 78/178 (43%), Gaps = 8/178 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECA--VRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT S++C+C PGY+ G+ DEC C C N G+Y C C G+ L D
Sbjct: 52 NTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCVHECINIPGNYRCTCFDGFMLAHD 111
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGR 365
G NC DVDEC+ + CQQIC N GSYEC C G+ + I+ +E C +
Sbjct: 112 GHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDH 171
Query: 366 -CVNLL-----GSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
C ++ G C C G+ L C G CQ C + G C C
Sbjct: 172 GCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYG-NGGCQHSCEDTDTGPMCGC 228
Score = 98.7 bits (235), Expect = 1e-20
Identities = 59/192 (30%), Positives = 84/192 (43%), Gaps = 11/192 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+N G++RC C G+ A G DEC C Q+C N GSY+C C +G+ L +
Sbjct: 92 INIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSD 151
Query: 183 DGANC----RDVDECERDTHTCQQICSNT-EGSYECSCEDGYE---KRGDACVDINECHE 338
+ C + C H C IC T +G C C G++ + D + N +
Sbjct: 152 NQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCN--YG 209
Query: 339 EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRNYAGGYRC 515
G C C + C C + Y L ++G C++ CA G C C++ A G RC
Sbjct: 210 NGGCQHS--CEDTDTGPMCGCHQKYALHSDGRTCIET--CAVNNGGCDRTCKDTATGVRC 265
Query: 516 DCPVGTVRSPSG 551
CPVG P G
Sbjct: 266 SCPVGFTLQPDG 277
Score = 97.9 bits (233), Expect = 2e-20
Identities = 55/168 (32%), Positives = 71/168 (42%), Gaps = 3/168 (1%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 200
G C C PG+ A C C C +TD C C Y L DG C
Sbjct: 183 GGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPMCGCHQKYALHSDGRTC- 241
Query: 201 DVDECERDTHTCQQICSNTEGSYECSCEDGY--EKRGDACVDINECH-EEGVCPSPGRCV 371
++ C + C + C +T CSC G+ + G C DINEC G C C
Sbjct: 242 -IETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDH--FCR 298
Query: 372 NLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRC 515
N +GSF C C +GY+L + C D DEC+ C C N G ++C
Sbjct: 299 NTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDHICINSPGSFQC 346
Score = 94.7 bits (225), Expect = 2e-19
Identities = 46/124 (37%), Positives = 60/124 (48%), Gaps = 2/124 (1%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDE 212
C C Y G + CAV CD+ C +T C C G+ L DG C+D++E
Sbjct: 226 CGCHQKYALHSDGRTCIETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINE 285
Query: 213 CERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLLGS 386
C + C C NT GS+EC C GY+ D C DI+EC E C C+N GS
Sbjct: 286 CLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDH--ICINSPGS 343
Query: 387 FRCV 398
F+C+
Sbjct: 344 FQCL 347
Score = 86.2 bits (204), Expect = 7e-17
Identities = 53/183 (28%), Positives = 73/183 (39%), Gaps = 9/183 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRG---VRGRDE---CAVRPPPCDQLCHNTD-GSYDCLCRTG 167
VN +GS+ C C G+ + + +E C + C +C T G C CR G
Sbjct: 133 VNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPG 192
Query: 168 YELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECH-EEG 344
++L ++ +C C CQ C +T+ C C Y D I C G
Sbjct: 193 FDLAQNQKDCTLT--CNYGNGGCQHSCEDTDTGPMCGCHQKYALHSDGRTCIETCAVNNG 250
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC-AQTGRCQAPCRNYAGGYRCDC 521
C C + RC CP G+ L +G C D +EC G C CRN G + C C
Sbjct: 251 GCDRT--CKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGC 308
Query: 522 PVG 530
G
Sbjct: 309 RKG 311
Score = 56.4 bits (130), Expect = 6e-08
Identities = 31/83 (37%), Positives = 40/83 (48%), Gaps = 4/83 (4%)
Frame = +3
Query: 315 VDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ---TGRCQA 482
VD++EC E C C N S++C+C GY+ EG +C D DEC G C
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYK--GEGKQCEDIDECENDYYNGGCVH 89
Query: 483 PCRNYAGGYRCDCPVGTVRSPSG 551
C N G YRC C G + + G
Sbjct: 90 ECINIPGNYRCTCFDGFMLAHDG 112
Score = 44.4 bits (100), Expect = 3e-04
Identities = 21/52 (40%), Positives = 29/52 (55%), Gaps = 2/52 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCR 161
NT+GSF C C GY+ R + DEC+ CD +C N+ GS+ CL +
Sbjct: 299 NTVGSFECGCRKGYKLLTDERTCQDIDECSFE-RTCDHICINSPGSFQCLIK 349
>BC047916-1|AAH47916.1| 347|Homo sapiens SCUBE1 protein protein.
Length = 347
Score = 107 bits (258), Expect = 2e-23
Identities = 64/177 (36%), Positives = 83/177 (46%), Gaps = 16/177 (9%)
Frame = +3
Query: 48 GYRPAGRGVRGR---DECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDE 212
G G G+ G DEC+ C D +C NT SY CLC+ GY+ +G C D+DE
Sbjct: 20 GRLAGGSGLPGSVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYK--GEGKQCEDIDE 77
Query: 213 CERDTHT--CQQICSNTEGSYECSCEDGY--EKRGDACVDINECHE-EGVCPSPGRCVNL 377
CE D + C C N G+Y C+C DG+ G C+D++EC + G C CVN
Sbjct: 78 CENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ--ICVNA 135
Query: 378 LGSFRCVCPRGYRLDAEGARCVDRD----ECAQTGR-CQAPCRNY-AGGYRCDCPVG 530
+GS+ C C G+ L C+ R C C CR GG CDC G
Sbjct: 136 MGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPG 192
Score = 104 bits (249), Expect = 2e-22
Identities = 60/178 (33%), Positives = 78/178 (43%), Gaps = 8/178 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECA--VRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT S++C+C PGY+ G+ DEC C C N G+Y C C G+ L D
Sbjct: 52 NTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCVHECINIPGNYRCTCFDGFMLAHD 111
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGR 365
G NC DVDEC+ + CQQIC N GSYEC C G+ + I+ +E C +
Sbjct: 112 GHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDH 171
Query: 366 -CVNLL-----GSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
C ++ G C C G+ L C G CQ C + G C C
Sbjct: 172 GCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYG-NGGCQHSCEDTDTGPTCGC 228
Score = 77.8 bits (183), Expect = 2e-14
Identities = 61/220 (27%), Positives = 86/220 (39%), Gaps = 39/220 (17%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
+N G++RC C G+ A G DEC C Q+C N GSY+C C +G+ L +
Sbjct: 92 INIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSD 151
Query: 183 DGANC----RDVDECERDTHTCQQICSNT-EGSYECSCEDGYE---KRGDACVDINECHE 338
+ C + C H C IC T +G C C G++ + D + N +
Sbjct: 152 NQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCN--YG 209
Query: 339 EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC--------------------VDR--- 449
G C C + C C + Y L ++G C VD+
Sbjct: 210 NGGCQHS--CEDTDTGPTCGCHQKYALHSDGRTCIEKDEAAIERSQFNATSVADVDKRVK 267
Query: 450 -----DECA-QTGRCQAPCRNYAGGYRCDCPVGTVRSPSG 551
+ CA G C C++ A G RC CPVG P G
Sbjct: 268 RRLLMETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDG 307
Score = 56.4 bits (130), Expect = 6e-08
Identities = 31/83 (37%), Positives = 40/83 (48%), Gaps = 4/83 (4%)
Frame = +3
Query: 315 VDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQ---TGRCQA 482
VD++EC E C C N S++C+C GY+ EG +C D DEC G C
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYK--GEGKQCEDIDECENDYYNGGCVH 89
Query: 483 PCRNYAGGYRCDCPVGTVRSPSG 551
C N G YRC C G + + G
Sbjct: 90 ECINIPGNYRCTCFDGFMLAHDG 112
Score = 36.7 bits (81), Expect = 0.054
Identities = 14/39 (35%), Positives = 19/39 (48%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 200
+ CAV CD+ C +T C C G+ L DG C+
Sbjct: 273 ETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCK 311
>AL021578-3|CAB46380.1| 622|Homo sapiens matrilin 4 protein.
Length = 622
Score = 103 bits (246), Expect = 6e-22
Identities = 51/151 (33%), Positives = 73/151 (48%), Gaps = 7/151 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN F C C PGY+ A + D CA C+ C N+ GSY C C+ G+ L +
Sbjct: 231 VNAWAMFHCTCNPGYKLAADNKSCLAIDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQ 290
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPG 362
D +CR +D C H+CQ C +T G C C +G++ + D C +C
Sbjct: 291 DQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDG----RSCQVRDLCNGVD 346
Query: 363 -----RCVNLLGSFRCVCPRGYRLDAEGARC 440
+CV+ S+RC+CP G +L A+G C
Sbjct: 347 HGCEFQCVSEGLSYRCLCPEGRQLQADGKSC 377
Score = 101 bits (243), Expect = 1e-21
Identities = 53/154 (34%), Positives = 71/154 (46%), Gaps = 3/154 (1%)
Frame = +3
Query: 78 GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNT 257
G+D+CA C C N + C C GY+L D +C +D C TH C+ C N+
Sbjct: 215 GKDQCAEGGHGCQHQCVNAWAMFHCTCNPGYKLAADNKSCLAIDLCAEGTHGCEHHCVNS 274
Query: 258 EGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEG 431
GSY C C+ G+ + D +C I+ C G CV+ G RC C G+ L +G
Sbjct: 275 PGSYFCHCQVGFVLQQDQRSCRAIDYC-SFGNHSCQHECVSTPGGPRCHCREGHDLQPDG 333
Query: 432 ARCVDRDECAQTGR-CQAPCRNYAGGYRCDCPVG 530
C RD C C+ C + YRC CP G
Sbjct: 334 RSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEG 367
Score = 72.9 bits (171), Expect = 7e-13
Identities = 47/156 (30%), Positives = 66/156 (42%), Gaps = 3/156 (1%)
Frame = +3
Query: 93 AVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYE 272
A+ PP D+ + S+D + G + + D+C H CQ C N +
Sbjct: 183 AMASPPLDEHVFLVE-SFDLIQEFGLQFQ---SRLCGKDQCAEGGHGCQHQCVNAWAMFH 238
Query: 273 CSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
C+C GY+ D +C+ I+ C EG CVN GS+ C C G+ L + C
Sbjct: 239 CTCNPGYKLAADNKSCLAIDLC-AEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRA 297
Query: 447 RDECAQTGR-CQAPCRNYAGGYRCDCPVGTVRSPSG 551
D C+ CQ C + GG RC C G P G
Sbjct: 298 IDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDG 333
>AL021578-1|CAI21077.1| 432|Homo sapiens matrilin 4 protein.
Length = 432
Score = 103 bits (246), Expect = 6e-22
Identities = 51/151 (33%), Positives = 73/151 (48%), Gaps = 7/151 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN F C C PGY+ A + D CA C+ C N+ GSY C C+ G+ L +
Sbjct: 41 VNAWAMFHCTCNPGYKLAADNKSCLAIDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQ 100
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPG 362
D +CR +D C H+CQ C +T G C C +G++ + D C +C
Sbjct: 101 DQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDG----RSCQVRDLCNGVD 156
Query: 363 -----RCVNLLGSFRCVCPRGYRLDAEGARC 440
+CV+ S+RC+CP G +L A+G C
Sbjct: 157 HGCEFQCVSEGLSYRCLCPEGRQLQADGKSC 187
Score = 101 bits (243), Expect = 1e-21
Identities = 53/154 (34%), Positives = 71/154 (46%), Gaps = 3/154 (1%)
Frame = +3
Query: 78 GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNT 257
G+D+CA C C N + C C GY+L D +C +D C TH C+ C N+
Sbjct: 25 GKDQCAEGGHGCQHQCVNAWAMFHCTCNPGYKLAADNKSCLAIDLCAEGTHGCEHHCVNS 84
Query: 258 EGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEG 431
GSY C C+ G+ + D +C I+ C G CV+ G RC C G+ L +G
Sbjct: 85 PGSYFCHCQVGFVLQQDQRSCRAIDYC-SFGNHSCQHECVSTPGGPRCHCREGHDLQPDG 143
Query: 432 ARCVDRDECAQTGR-CQAPCRNYAGGYRCDCPVG 530
C RD C C+ C + YRC CP G
Sbjct: 144 RSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEG 177
Score = 72.1 bits (169), Expect = 1e-12
Identities = 40/118 (33%), Positives = 52/118 (44%), Gaps = 3/118 (2%)
Frame = +3
Query: 207 DECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLL 380
D+C H CQ C N + C+C GY+ D +C+ I+ C EG CVN
Sbjct: 27 DQCAEGGHGCQHQCVNAWAMFHCTCNPGYKLAADNKSCLAIDLC-AEGTHGCEHHCVNSP 85
Query: 381 GSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQAPCRNYAGGYRCDCPVGTVRSPSG 551
GS+ C C G+ L + C D C+ CQ C + GG RC C G P G
Sbjct: 86 GSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDG 143
>AF193055-1|AAG22483.1| 474|Homo sapiens unknown protein.
Length = 474
Score = 102 bits (245), Expect = 7e-22
Identities = 57/158 (36%), Positives = 76/158 (48%), Gaps = 9/158 (5%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEG 263
+EC ++P PC C NT GSY C C +G+ L D A C + C CQ C +TE
Sbjct: 17 NECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPD-ATCVNSRTCA--MINCQYSCEDTEE 73
Query: 264 SYECSCEDG---YEKRGDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEG 431
+C C G C+DI+EC + +CP RCVN GS+ C C G+ L
Sbjct: 74 GPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYIS 133
Query: 432 AR--CVDRDEC---AQTGRCQAPCRNYAGGYRCDCPVG 530
R C+D +EC + T A C N G ++C C G
Sbjct: 134 GRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQG 171
Score = 96.3 bits (229), Expect = 6e-20
Identities = 58/156 (37%), Positives = 77/156 (49%), Gaps = 10/156 (6%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLC-RTGYE 173
R VNT GS++C C G+ P V R CA+ C C +T+ CLC +G
Sbjct: 29 RCVNTHGSYKCFCLSGHMLMPDATCVNSRT-CAMIN--CQYSCEDTEEGPQCLCPSSGLR 85
Query: 174 LDEDGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGDA----CVDINECH 335
L +G +C D+DEC C + C NT GSY C C G+E + + C+DINEC
Sbjct: 86 LAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECT 145
Query: 336 EEG-VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC 440
+ C C N GSF+C C +GY+ G RC
Sbjct: 146 MDSHTCSHHANCFNTQGSFKCKCKQGYK--GNGLRC 179
Score = 82.2 bits (194), Expect = 1e-15
Identities = 47/120 (39%), Positives = 63/120 (52%), Gaps = 9/120 (7%)
Frame = +3
Query: 30 RCVC-GPGYR--PAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGA- 191
+C+C G R P GR DECA C ++ C NT GSY C C G+EL
Sbjct: 76 QCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGR 135
Query: 192 -NCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPG 362
+C D++EC D+HTC C NT+GS++C C+ GY+ G C I E + V +PG
Sbjct: 136 YDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRCSAIPENSVKEVLRAPG 195
Score = 71.7 bits (168), Expect = 2e-12
Identities = 43/117 (36%), Positives = 56/117 (47%), Gaps = 6/117 (5%)
Frame = +3
Query: 198 RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDA-CVDINECHEEGVCPSPGRCVN 374
+DV+EC CQ C NT GSY+C C G+ DA CV+ C + C +
Sbjct: 14 QDVNECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPDATCVNSRTC---AMINCQYSCED 70
Query: 375 LLGSFRCVCP-RGYRLDAEGARCVDRDECAQTGRCQAP----CRNYAGGYRCDCPVG 530
+C+CP G RL G C+D DECA +G+ P C N G Y C C +G
Sbjct: 71 TEEGPQCLCPSSGLRLAPNGRDCLDIDECA-SGKVICPYNRRCVNTFGSYYCKCHIG 126
Score = 53.6 bits (123), Expect = 4e-07
Identities = 32/81 (39%), Positives = 44/81 (54%), Gaps = 3/81 (3%)
Frame = +3
Query: 318 DINECHEEGVCPSP--GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCR 491
D+NEC G+ P P RCVN GS++C C G+ L + A CV+ CA CQ C
Sbjct: 15 DVNEC---GMKPRPCQHRCVNTHGSYKCFCLSGHMLMPD-ATCVNSRTCAMIN-CQYSCE 69
Query: 492 NYAGGYRCDCPVGTVR-SPSG 551
+ G +C CP +R +P+G
Sbjct: 70 DTEEGPQCLCPSSGLRLAPNG 90
>AK131562-1|BAD18695.1| 867|Homo sapiens protein ( Homo sapiens
cDNA FLJ16811 fis, clone THYMU3024602, highly similar
to Cell surface glycoprotein EMR1 precursor. ).
Length = 867
Score = 102 bits (244), Expect = 1e-21
Identities = 72/213 (33%), Positives = 93/213 (43%), Gaps = 33/213 (15%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGR-------GVRGRD--EC---AVRPPPCDQLCHNTDGSYDCL 155
NT+ S+ C C G+ + GVR +D EC +V P D C N+ GSY C
Sbjct: 49 NTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDINECLTSSVCPEHSD--CVNSMGSYSCS 106
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGD------- 308
C+ G+ + C DVDEC D C + C+NT G+Y C C G+E
Sbjct: 107 CQVGFI--SRNSTCEDVDECA-DPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGL 163
Query: 309 --ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGY-------RLDAEGARCVDRDECA 461
+C DI+EC E +CP C N GS+ C C G+ +G C D DEC
Sbjct: 164 KASCEDIDECTE--MCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECR 221
Query: 462 QTGRCQAP---CRNYAGGYRCDCPVGTVRSPSG 551
Q P C N G Y C C G +P G
Sbjct: 222 QDPSTCGPNSICTNALGSYSCGCIAGFHPNPEG 254
Score = 101 bits (243), Expect = 1e-21
Identities = 57/178 (32%), Positives = 80/178 (44%), Gaps = 16/178 (8%)
Frame = +3
Query: 45 PGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGY-------ELDEDGANCRD 203
P +P +G RD P C NT SY C C+ G+ + G C+D
Sbjct: 24 PTRKPNTKGNNCRDSTLC---PAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKD 80
Query: 204 VDECERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNL 377
++EC + C + C N+ GSY CSC+ G+ R C D++EC + CP C N
Sbjct: 81 INECLTSS-VCPEHSDCVNSMGSYSCSCQVGFISRNSTCEDVDECADPRACPEHATCNNT 139
Query: 378 LGSFRCVCPRGY-----RLDAEG--ARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
+G++ C C G+ L +G A C D DEC + + C N G Y C C G
Sbjct: 140 VGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCPINSTCTNTPGSYFCTCHPG 197
Score = 96.3 bits (229), Expect = 6e-20
Identities = 58/163 (35%), Positives = 79/163 (48%), Gaps = 20/163 (12%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECA-VRPPPCDQLCHNTDGSYDCLCRTGYE---- 173
VN++GS+ C C G+ DECA R P C+NT G+Y C C G+E
Sbjct: 97 VNSMGSYSCSCQVGFISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSG 156
Query: 174 -LDEDG--ANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEK---------RGDA 311
L G A+C D+DEC T C C+NT GSY C+C G+ +G
Sbjct: 157 HLSFQGLKASCEDIDEC---TEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVE 213
Query: 312 CVDINECHEE-GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGAR 437
C DI+EC ++ C C N LGS+ C C G+ + EG++
Sbjct: 214 CRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQ 256
Score = 50.4 bits (115), Expect = 4e-06
Identities = 29/88 (32%), Positives = 42/88 (47%), Gaps = 11/88 (12%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG-------RGVRGRD--ECAVRPPPC--DQLCHNTDGSYDCLC 158
NT GS+ C C PG+ P+ +GV RD EC P C + +C N GSY C C
Sbjct: 185 NTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGC 244
Query: 159 RTGYELDEDGANCRDVDECERDTHTCQQ 242
G+ + +G+ C+R C++
Sbjct: 245 IAGFHPNPEGSQKDGNFSCQRVLFKCKE 272
>AK056571-1|BAB71219.1| 955|Homo sapiens protein ( Homo sapiens
cDNA FLJ32009 fis, clone NT2RP7009498, weakly similar to
FIBULIN-1, ISOFORM A PRECURSOR. ).
Length = 955
Score = 102 bits (244), Expect = 1e-21
Identities = 55/141 (39%), Positives = 71/141 (50%), Gaps = 5/141 (3%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDE 212
C G A G+R D C+ C NT+G + C C G +L D +C+D DE
Sbjct: 125 CPVGFSMTEAAVGIRCTDIDECVTSSCEGHCVNTEGGFVCECGPGMQLSADRHSCQDTDE 184
Query: 213 CERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECH---EEGVCPSPGRCVNL 377
C CQQ C N+ GSY+CSC G+ G+ +CVD+NEC E VC C N
Sbjct: 185 CLGT--PCQQRCKNSIGSYKCSCRTGFHLHGNRHSCVDVNECRRPLERRVCHH--SCHNT 240
Query: 378 LGSFRCVCPRGYRLDAEGARC 440
+GSF C C G+RL A+ C
Sbjct: 241 VGSFLCTCRPGFRLRADRVSC 261
Score = 91.5 bits (217), Expect = 2e-18
Identities = 44/104 (42%), Positives = 56/104 (53%), Gaps = 4/104 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VNT G F C CGPG + + + DEC PC Q C N+ GSY C CRTG+ L
Sbjct: 156 VNTEGGFVCECGPGMQLSADRHSCQDTDECL--GTPCQQRCKNSIGSYKCSCRTGFHLHG 213
Query: 183 DGANCRDVDECER--DTHTCQQICSNTEGSYECSCEDGYEKRGD 308
+ +C DV+EC R + C C NT GS+ C+C G+ R D
Sbjct: 214 NRHSCVDVNECRRPLERRVCHHSCHNTVGSFLCTCRPGFRLRAD 257
Score = 89.4 bits (212), Expect = 7e-18
Identities = 51/149 (34%), Positives = 69/149 (46%), Gaps = 9/149 (6%)
Frame = +3
Query: 111 CDQLCHNTDGSYDC--LCRTGYELDED--GANCRDVDECERDTHTCQQICSNTEGSYECS 278
CD C N G + +C G+ + E G C D+DEC T +C+ C NTEG + C
Sbjct: 109 CDLTC-NHGGCQEVARVCPVGFSMTEAAVGIRCTDIDECV--TSSCEGHCVNTEGGFVCE 165
Query: 279 CEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRD 452
C G + D +C D +EC P RC N +GS++C C G+ L CVD +
Sbjct: 166 CGPGMQLSADRHSCQDTDECLG---TPCQQRCKNSIGSYKCSCRTGFHLHGNRHSCVDVN 222
Query: 453 EC---AQTGRCQAPCRNYAGGYRCDCPVG 530
EC + C C N G + C C G
Sbjct: 223 ECRRPLERRVCHHSCHNTVGSFLCTCRPG 251
>D89629-1|BAB46925.1| 815|Homo sapiens cerebral protein-12 protein.
Length = 815
Score = 101 bits (242), Expect = 2e-21
Identities = 72/189 (38%), Positives = 89/189 (47%), Gaps = 15/189 (7%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY-RPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELD 179
VNT GSF C+C GY R DEC CD+ LC NT G ++C+C+ GY
Sbjct: 457 VNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGYT-- 514
Query: 180 EDGANCRDV--DECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGV- 347
+G C+ D C R+ C I +N C+C G+ G +C DI+EC + V
Sbjct: 515 GNGTTCKAFCKDGC-RNGGAC--IAANV-----CACPQGFT--GPSCETDIDECSDGFVQ 564
Query: 348 CPSPGRCVNLLGSFRCVCPRGYR----LDAEGARCVDRDECAQTGR--C--QAPCRNYAG 503
C S C+NL G + C C GY G C D DEC TGR C C N G
Sbjct: 565 CDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECG-TGRHSCANDTICFNLDG 623
Query: 504 GYRCDCPVG 530
GY C CP G
Sbjct: 624 GYDCRCPHG 632
Score = 91.5 bits (217), Expect = 2e-18
Identities = 48/142 (33%), Positives = 69/142 (48%), Gaps = 6/142 (4%)
Frame = +3
Query: 75 RGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYE-LDEDGANCRDVDECERDTHTCQQ-- 242
+G D C+ R + +C N + C CR G+ L ED A C D+DEC H C++
Sbjct: 395 KGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRENT 454
Query: 243 ICSNTEGSYECSCEDGYEKRGD-ACVDINEC-HEEGVCPSPGRCVNLLGSFRCVCPRGYR 416
+C NT GS+ C C+ GY + D +C + +EC + C C N +G CVC GY
Sbjct: 455 MCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGYT 514
Query: 417 LDAEGARCVDRDECAQTGRCQA 482
+ + +D C G C A
Sbjct: 515 GNGTTCKAFCKDGCRNGGACIA 536
Score = 63.3 bits (147), Expect = 5e-10
Identities = 33/87 (37%), Positives = 39/87 (44%), Gaps = 8/87 (9%)
Frame = +3
Query: 84 DECAVRPPPCDQL--CHNTDGSYDCLCRTGYE----LDEDGANCRDVDECERDTHTCQQ- 242
DEC+ CD C N G Y C CR GY G +C D+DEC H+C
Sbjct: 556 DECSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCAND 615
Query: 243 -ICSNTEGSYECSCEDGYEKRGDACVD 320
IC N +G Y+C C G GD D
Sbjct: 616 TICFNLDGGYDCRCPHGKNCTGDCIHD 642
Score = 44.4 bits (100), Expect = 3e-04
Identities = 29/81 (35%), Positives = 36/81 (44%), Gaps = 5/81 (6%)
Frame = +3
Query: 312 CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYR-LDAEGARCVDRDECAQTGR--CQ- 479
C + C E C C NL C C G+R L + A C D DECA+ GR C+
Sbjct: 394 CKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAE-GRHYCRE 452
Query: 480 -APCRNYAGGYRCDCPVGTVR 539
C N G + C C G +R
Sbjct: 453 NTMCVNTPGSFMCICKTGYIR 473
>D83018-1|BAA11681.1| 816|Homo sapiens nel-related protein 2
protein.
Length = 816
Score = 101 bits (242), Expect = 2e-21
Identities = 72/189 (38%), Positives = 89/189 (47%), Gaps = 15/189 (7%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY-RPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELD 179
VNT GSF C+C GY R DEC CD+ LC NT G ++C+C+ GY
Sbjct: 458 VNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGYT-- 515
Query: 180 EDGANCRDV--DECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGV- 347
+G C+ D C R+ C I +N C+C G+ G +C DI+EC + V
Sbjct: 516 GNGTTCKAFCKDGC-RNGGAC--IAANV-----CACPQGFT--GPSCETDIDECSDGFVQ 565
Query: 348 CPSPGRCVNLLGSFRCVCPRGYR----LDAEGARCVDRDECAQTGR--C--QAPCRNYAG 503
C S C+NL G + C C GY G C D DEC TGR C C N G
Sbjct: 566 CDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECG-TGRHSCANDTICFNLDG 624
Query: 504 GYRCDCPVG 530
GY C CP G
Sbjct: 625 GYDCRCPHG 633
Score = 91.5 bits (217), Expect = 2e-18
Identities = 48/142 (33%), Positives = 69/142 (48%), Gaps = 6/142 (4%)
Frame = +3
Query: 75 RGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYE-LDEDGANCRDVDECERDTHTCQQ-- 242
+G D C+ R + +C N + C CR G+ L ED A C D+DEC H C++
Sbjct: 396 KGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRENT 455
Query: 243 ICSNTEGSYECSCEDGYEKRGD-ACVDINEC-HEEGVCPSPGRCVNLLGSFRCVCPRGYR 416
+C NT GS+ C C+ GY + D +C + +EC + C C N +G CVC GY
Sbjct: 456 MCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGYT 515
Query: 417 LDAEGARCVDRDECAQTGRCQA 482
+ + +D C G C A
Sbjct: 516 GNGTTCKAFCKDGCRNGGACIA 537
Score = 63.3 bits (147), Expect = 5e-10
Identities = 33/87 (37%), Positives = 39/87 (44%), Gaps = 8/87 (9%)
Frame = +3
Query: 84 DECAVRPPPCDQL--CHNTDGSYDCLCRTGYE----LDEDGANCRDVDECERDTHTCQQ- 242
DEC+ CD C N G Y C CR GY G +C D+DEC H+C
Sbjct: 557 DECSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCAND 616
Query: 243 -ICSNTEGSYECSCEDGYEKRGDACVD 320
IC N +G Y+C C G GD D
Sbjct: 617 TICFNLDGGYDCRCPHGKNCTGDCIHD 643
Score = 44.4 bits (100), Expect = 3e-04
Identities = 29/81 (35%), Positives = 36/81 (44%), Gaps = 5/81 (6%)
Frame = +3
Query: 312 CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYR-LDAEGARCVDRDECAQTGR--CQ- 479
C + C E C C NL C C G+R L + A C D DECA+ GR C+
Sbjct: 395 CKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAE-GRHYCRE 453
Query: 480 -APCRNYAGGYRCDCPVGTVR 539
C N G + C C G +R
Sbjct: 454 NTMCVNTPGSFMCICKTGYIR 474
>BC020544-1|AAH20544.1| 816|Homo sapiens NELL2 protein protein.
Length = 816
Score = 101 bits (242), Expect = 2e-21
Identities = 72/189 (38%), Positives = 89/189 (47%), Gaps = 15/189 (7%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY-RPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELD 179
VNT GSF C+C GY R DEC CD+ LC NT G ++C+C+ GY
Sbjct: 458 VNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGYT-- 515
Query: 180 EDGANCRDV--DECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGV- 347
+G C+ D C R+ C I +N C+C G+ G +C DI+EC + V
Sbjct: 516 GNGTTCKAFCKDGC-RNGGAC--IAANV-----CACPQGFT--GPSCETDIDECSDGFVQ 565
Query: 348 CPSPGRCVNLLGSFRCVCPRGYR----LDAEGARCVDRDECAQTGR--C--QAPCRNYAG 503
C S C+NL G + C C GY G C D DEC TGR C C N G
Sbjct: 566 CDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECG-TGRHSCANDTICFNLDG 624
Query: 504 GYRCDCPVG 530
GY C CP G
Sbjct: 625 GYDCRCPHG 633
Score = 91.5 bits (217), Expect = 2e-18
Identities = 48/142 (33%), Positives = 69/142 (48%), Gaps = 6/142 (4%)
Frame = +3
Query: 75 RGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYE-LDEDGANCRDVDECERDTHTCQQ-- 242
+G D C+ R + +C N + C CR G+ L ED A C D+DEC H C++
Sbjct: 396 KGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRENT 455
Query: 243 ICSNTEGSYECSCEDGYEKRGD-ACVDINEC-HEEGVCPSPGRCVNLLGSFRCVCPRGYR 416
+C NT GS+ C C+ GY + D +C + +EC + C C N +G CVC GY
Sbjct: 456 MCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGYT 515
Query: 417 LDAEGARCVDRDECAQTGRCQA 482
+ + +D C G C A
Sbjct: 516 GNGTTCKAFCKDGCRNGGACIA 537
Score = 63.3 bits (147), Expect = 5e-10
Identities = 33/87 (37%), Positives = 39/87 (44%), Gaps = 8/87 (9%)
Frame = +3
Query: 84 DECAVRPPPCDQL--CHNTDGSYDCLCRTGYE----LDEDGANCRDVDECERDTHTCQQ- 242
DEC+ CD C N G Y C CR GY G +C D+DEC H+C
Sbjct: 557 DECSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCAND 616
Query: 243 -ICSNTEGSYECSCEDGYEKRGDACVD 320
IC N +G Y+C C G GD D
Sbjct: 617 TICFNLDGGYDCRCPHGKNCTGDCIHD 643
Score = 44.4 bits (100), Expect = 3e-04
Identities = 29/81 (35%), Positives = 36/81 (44%), Gaps = 5/81 (6%)
Frame = +3
Query: 312 CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYR-LDAEGARCVDRDECAQTGR--CQ- 479
C + C E C C NL C C G+R L + A C D DECA+ GR C+
Sbjct: 395 CKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAE-GRHYCRE 453
Query: 480 -APCRNYAGGYRCDCPVGTVR 539
C N G + C C G +R
Sbjct: 454 NTMCVNTPGSFMCICKTGYIR 474
>BC142624-1|AAI42625.1| 955|Homo sapiens von Willebrand factor C
and EGF domains protein.
Length = 955
Score = 101 bits (241), Expect = 2e-21
Identities = 52/124 (41%), Positives = 67/124 (54%), Gaps = 5/124 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEG 263
DEC C+ C NT+G + C C G +L D +C+D DEC CQQ C N+ G
Sbjct: 144 DECVTSS--CEGHCVNTEGGFVCECGPGMQLSADRHSCQDTDECLGT--PCQQRCKNSIG 199
Query: 264 SYECSCEDGYEKRGD--ACVDINECH---EEGVCPSPGRCVNLLGSFRCVCPRGYRLDAE 428
SY+CSC G+ G+ +CVD+NEC E VC C N +GSF C C G+RL A+
Sbjct: 200 SYKCSCRTGFHLHGNRHSCVDVNECRRPLERRVCHH--SCHNTVGSFLCTCRPGFRLRAD 257
Query: 429 GARC 440
C
Sbjct: 258 RVSC 261
Score = 91.5 bits (217), Expect = 2e-18
Identities = 44/104 (42%), Positives = 56/104 (53%), Gaps = 4/104 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAG--RGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VNT G F C CGPG + + + DEC PC Q C N+ GSY C CRTG+ L
Sbjct: 156 VNTEGGFVCECGPGMQLSADRHSCQDTDECL--GTPCQQRCKNSIGSYKCSCRTGFHLHG 213
Query: 183 DGANCRDVDECER--DTHTCQQICSNTEGSYECSCEDGYEKRGD 308
+ +C DV+EC R + C C NT GS+ C+C G+ R D
Sbjct: 214 NRHSCVDVNECRRPLERRVCHHSCHNTVGSFLCTCRPGFRLRAD 257
Score = 89.8 bits (213), Expect = 5e-18
Identities = 51/149 (34%), Positives = 69/149 (46%), Gaps = 9/149 (6%)
Frame = +3
Query: 111 CDQLCHNTDGSYDC--LCRTGYELDED--GANCRDVDECERDTHTCQQICSNTEGSYECS 278
CD C N G + +C G+ + E G C D+DEC T +C+ C NTEG + C
Sbjct: 109 CDLTC-NHGGCQEVARVCPVGFSMTETAVGIRCTDIDECV--TSSCEGHCVNTEGGFVCE 165
Query: 279 CEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRD 452
C G + D +C D +EC P RC N +GS++C C G+ L CVD +
Sbjct: 166 CGPGMQLSADRHSCQDTDECLG---TPCQQRCKNSIGSYKCSCRTGFHLHGNRHSCVDVN 222
Query: 453 EC---AQTGRCQAPCRNYAGGYRCDCPVG 530
EC + C C N G + C C G
Sbjct: 223 ECRRPLERRVCHHSCHNTVGSFLCTCRPG 251
>AB209448-1|BAD92685.1| 1241|Homo sapiens nidogen (enactin) variant
protein.
Length = 1241
Score = 101 bits (241), Expect = 2e-21
Identities = 59/163 (36%), Positives = 78/163 (47%), Gaps = 12/163 (7%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANCR 200
F C C G+R GR DEC+ +P C +C+N G++ C C GY+ ++G
Sbjct: 692 FTCECSIGFRGDGRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVA 751
Query: 201 DVDE-----CERDTHTC----QQICSNTEGS-YECSCEDGYEKRGDACVDINECHEEGVC 350
VD+ CE H C + C T GS Y CSC G+ G AC D++ECH C
Sbjct: 752 VVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGFSGDGQACQDVDECHPSR-C 810
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ 479
C N GSF C C GY+ +G RCV + + RCQ
Sbjct: 811 HPDAFCYNTPGSFTCQCKPGYQ--GDGFRCVPGE--VEKTRCQ 849
Score = 63.3 bits (147), Expect = 5e-10
Identities = 39/114 (34%), Positives = 49/114 (42%), Gaps = 12/114 (10%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGV-------RGRDECAVRPPPCD-----QLCHNTDGSYDCL 155
N G+FRC C GY+ + G R + C CD Q + SY C
Sbjct: 728 NHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCS 787
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV 317
C G+ DG C+DVDEC C NT GS+ C C+ GY+ G CV
Sbjct: 788 CLPGFS--GDGQACQDVDECHPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCV 839
Score = 40.7 bits (91), Expect = 0.003
Identities = 23/58 (39%), Positives = 29/58 (50%), Gaps = 3/58 (5%)
Frame = +3
Query: 387 FRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAP--CRNYAGGYRCDCPVGTVRSPSG 551
F C C G+R D G C D DEC+ Q C + C N+ G +RC+C G S G
Sbjct: 692 FTCECSIGFRGD--GRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEG 747
>AK074499-1|BAC11024.1| 636|Homo sapiens protein ( Homo sapiens
cDNA FLJ90018 fis, clone HEMBA1000732, highly similar to
Homo sapiens mRNA for latent transforming growth
factor-beta ).
Length = 636
Score = 100 bits (240), Expect = 3e-21
Identities = 60/142 (42%), Positives = 74/142 (52%), Gaps = 8/142 (5%)
Frame = +3
Query: 42 GPGYR-PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDEC- 215
GPG R P V DEC+ +C NTDGS++C+C G+ D A+C DVDEC
Sbjct: 8 GPGLRTPCPADV---DECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECR 64
Query: 216 ERDTHTCQ-QICSNTEGSYEC--SCEDGYEKRGD-ACVDINECHE-EGVCPSPGRCVNLL 380
ER C+ Q C N+ GSY C C+ GY + C D+NEC +GVC C N+
Sbjct: 65 ERGPALCRSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVNECETLQGVC-GAALCENVE 123
Query: 381 GSFRCVCPRG-YRLDAEGARCV 443
GSF CVCP D RCV
Sbjct: 124 GSFLCVCPNSPEEFDPMTGRCV 145
Score = 89.0 bits (211), Expect = 1e-17
Identities = 50/116 (43%), Positives = 63/116 (54%), Gaps = 8/116 (6%)
Frame = +3
Query: 201 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEG--VCPSPGRC 368
DVDEC + IC+NT+GS+EC C G+ D +C+D++EC E G +C S RC
Sbjct: 18 DVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCRSQ-RC 76
Query: 369 VNLLGSFRCV--CPRGYRLDAEGARCVDRDECAQT-GRCQAP-CRNYAGGYRCDCP 524
N GS+RCV C GY EG C D +EC G C A C N G + C CP
Sbjct: 77 ENSPGSYRCVRDCDPGYHAGPEGT-CDDVNECETLQGVCGAALCENVEGSFLCVCP 131
Score = 74.5 bits (175), Expect = 2e-13
Identities = 43/103 (41%), Positives = 53/103 (51%), Gaps = 7/103 (6%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPP-C-DQLCHNTDGSYDCL--CRTGYE 173
NT GSF C+C PG+R P DEC R P C Q C N+ GSY C+ C GY
Sbjct: 35 NTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCRSQRCENSPGSYRCVRDCDPGYH 94
Query: 174 LDEDGANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYEK 299
+G C DV+ECE C +C N EGS+ C C + E+
Sbjct: 95 AGPEG-TCDDVNECETLQGVCGAALCENVEGSFLCVCPNSPEE 136
Score = 74.1 bits (174), Expect = 3e-13
Identities = 37/83 (44%), Positives = 47/83 (56%), Gaps = 5/83 (6%)
Frame = +3
Query: 318 DINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG--RCQAP-C 488
D++EC EE +C S G C N GSF C+CP G+R + A C+D DEC + G C++ C
Sbjct: 18 DVDECSEEDLCQS-GICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCRSQRC 76
Query: 489 RNYAGGYRC--DCPVGTVRSPSG 551
N G YRC DC G P G
Sbjct: 77 ENSPGSYRCVRDCDPGYHAGPEG 99
Score = 71.7 bits (168), Expect = 2e-12
Identities = 43/120 (35%), Positives = 54/120 (45%), Gaps = 8/120 (6%)
Frame = +3
Query: 117 QLCHNTD-GSYDCLCR--TGYELDEDGANCR-DVDECE--RDTHTCQQICSNTEGSYECS 278
Q C T+ Y LC GY + R DVDEC+ RD +C NT Y C
Sbjct: 233 QQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCY 292
Query: 279 CEDGYEKRGDA--CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRD 452
C +GY C+D +EC +E GRCVN +GS+ C C LD RCV +
Sbjct: 293 CSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNE 352
Score = 66.9 bits (156), Expect = 4e-11
Identities = 45/154 (29%), Positives = 63/154 (40%), Gaps = 6/154 (3%)
Frame = +3
Query: 78 GRDEC---AVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECE-RDTHTCQQI 245
GR EC P CD + +C C G + G+ CR + +C +T Q +
Sbjct: 191 GRRECYFDTAAPDACDNILARNVTWQECCCTVG---EGWGSGCR-IQQCPGTETAEYQSL 246
Query: 246 CSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDA 425
C + G S + + D C + + VC S G CVN + C C GY
Sbjct: 247 CPHGRGYLAPSGDLSLRRDVDEC----QLFRDQVCKS-GVCVNTAPGYSCYCSNGYYYHT 301
Query: 426 EGARCVDRDECA-QTGRCQ-APCRNYAGGYRCDC 521
+ C+D DECA + C+ C N G Y C C
Sbjct: 302 QRLECIDNDECADEEPACEGGRCVNTVGSYHCTC 335
Score = 52.8 bits (121), Expect = 8e-07
Identities = 36/95 (37%), Positives = 45/95 (47%), Gaps = 5/95 (5%)
Frame = +3
Query: 261 GSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC 440
GSY S + YE+ ++ EC C + GRCV + F C C GYRLD C
Sbjct: 531 GSYAGSLAEPYEE-----LEAEECGILDGCTN-GRCVRVPEGFTCRCFDGYRLDMTRMAC 584
Query: 441 VDRDEC----AQTGRC-QAPCRNYAGGYRCDCPVG 530
VD +EC A + C A C N G +RC C G
Sbjct: 585 VDINECDEAEAASPLCVNARCLNTDGSFRCICRPG 619
Score = 51.6 bits (118), Expect = 2e-06
Identities = 27/61 (44%), Positives = 32/61 (52%), Gaps = 5/61 (8%)
Frame = +3
Query: 246 CSNTEGSYECSCEDGY--EKRGDACVDINECHE-EGVCPS--PGRCVNLLGSFRCVCPRG 410
C + C C DGY + ACVDINEC E E P RC+N GSFRC+C G
Sbjct: 560 CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPG 619
Query: 411 Y 413
+
Sbjct: 620 F 620
Score = 46.8 bits (106), Expect = 5e-05
Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 4/74 (5%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDEC---ERDTHTCQQI-CS 251
+EC + + C + C C GY LD C D++EC E + C C
Sbjct: 547 EECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCL 606
Query: 252 NTEGSYECSCEDGY 293
NT+GS+ C C G+
Sbjct: 607 NTDGSFRCICRPGF 620
Score = 42.7 bits (96), Expect = 8e-04
Identities = 24/66 (36%), Positives = 28/66 (42%), Gaps = 3/66 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCD-QLCHNTDGSYDCLCRTGYELD 179
VNT + C C GY + + DECA P C+ C NT GSY C C LD
Sbjct: 283 VNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLD 342
Query: 180 EDGANC 197
C
Sbjct: 343 GSQRRC 348
Score = 38.3 bits (85), Expect = 0.018
Identities = 24/71 (33%), Positives = 30/71 (42%), Gaps = 6/71 (8%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYR-----PAGRGVRGRDECAVRPPPC-DQLCHNTDGSYDCLCRT 164
R V F C C GYR A + DE P C + C NTDGS+ C+CR
Sbjct: 559 RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRP 618
Query: 165 GYELDEDGANC 197
G+ +C
Sbjct: 619 GFAPTHQPHHC 629
>BC071562-1|AAH71562.2| 1235|Homo sapiens NOTCH2 protein protein.
Length = 1235
Score = 100 bits (239), Expect = 4e-21
Identities = 60/177 (33%), Positives = 87/177 (49%), Gaps = 7/177 (3%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAV-RPPPCDQL--CHNTDGSYDCLCRTGYELDEDGA 191
G + C C GY+ A DECA+ PC+ C NTDG++ C C GY G
Sbjct: 397 GQYICTCPQGYKGADC-TEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYA----GP 451
Query: 192 NCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGR 365
C D++EC D C + G + C C G+ +G C ++INEC + C + G+
Sbjct: 452 RCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGF--KGVHCELEINEC-QSNPCVNNGQ 508
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ-APCRNYAGGYRCDCPVG 530
CV+ + F+C+CP G+ G C +D D+C+ T A C ++ GY C C G
Sbjct: 509 CVDKVNRFQCLCPPGF----TGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATG 561
Score = 87.4 bits (207), Expect = 3e-17
Identities = 58/178 (32%), Positives = 89/178 (50%), Gaps = 5/178 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGV-RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
NT GS+ C C PG+ +G D+C P C + ++ CLC G+ D+
Sbjct: 890 NTQGSYMCECPPGF--SGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKYQ 947
Query: 189 ANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSPGR 365
D++EC + CS+ SY C C+ G++ G C +INEC E C + G
Sbjct: 948 T---DMNECLSEPCKNGGTCSDYVNSYTCKCQAGFD--GVHCENNINECTESS-CFNGGT 1001
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARCV-DRDECAQTGRC--QAPCRNYAGGYRCDCPVG 530
CV+ + SF C+CP G+ G+ C+ + +EC+ + C + C + G YRC CP+G
Sbjct: 1002 CVDGINSFSCLCPVGF----TGSFCLHEINECS-SHPCLNEGTCVDGLGTYRCSCPLG 1054
Score = 86.6 bits (205), Expect = 5e-17
Identities = 54/173 (31%), Positives = 81/173 (46%), Gaps = 4/173 (2%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-R 200
S+ C+C PG++ R DEC +P LCHNT GSY C C G+ G +C
Sbjct: 856 SYTCLCAPGWQ-GQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGF----SGMDCEE 910
Query: 201 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNL 377
D+D+C + C + ++ C C G+ GD D+NEC E C + G C +
Sbjct: 911 DIDDCLANPCQNGGSCMDGVNTFSCLCLPGF--TGDKYQTDMNECLSE-PCKNGGTCSDY 967
Query: 378 LGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ-APCRNYAGGYRCDCPVG 530
+ S+ C C G+ +G C + +EC ++ C + + C CPVG
Sbjct: 968 VNSYTCKCQAGF----DGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVG 1016
Score = 81.8 bits (193), Expect = 1e-15
Identities = 54/176 (30%), Positives = 72/176 (40%), Gaps = 3/176 (1%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
I S+ C+C PGY A + DEC P D C + Y C C+ G G NC
Sbjct: 588 IDSYTCICNPGYMGAICSDQ-IDECYSSPCLNDGRCIDLVNGYQCNCQPG----TSGVNC 642
Query: 198 R-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCV 371
+ D+C + IC + Y C C G+ G C +DI+EC C C+
Sbjct: 643 EINFDDCASNP-CIHGICMDGINRYSCVCSPGFT--GQRCNIDIDEC-ASNPCRKGATCI 698
Query: 372 NLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQAPCRNYAGGYRCDCPVGTV 536
N + FRC+CP G C + +EC C GY+C C G V
Sbjct: 699 NGVNGFRCICPEG----PHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWV 750
Score = 80.6 bits (190), Expect = 3e-15
Identities = 52/177 (29%), Positives = 79/177 (44%), Gaps = 3/177 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
V+ + F+C+C PG+ + D+C+ P C + Y+C C TG+ G
Sbjct: 510 VDKVNRFQCLCPPGFTGPVCQI-DIDDCSSTPCLNGAKCIDHPNGYECQCATGFT----G 564
Query: 189 ANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCPSPG 362
C + +D C+ D Q C + SY C C GY G C D I+EC+ C + G
Sbjct: 565 VLCEENIDNCDPDPCHHGQ-CQDGIDSYTCICNPGY--MGAICSDQIDECYSSP-CLNDG 620
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
RC++L+ ++C C G G C ++ D+CA C + Y C C G
Sbjct: 621 RCIDLVNGYQCNCQPG----TSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPG 673
Score = 77.8 bits (183), Expect = 2e-14
Identities = 56/180 (31%), Positives = 76/180 (42%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N G + CVC G+ D+CA C + S+ C+C G + G
Sbjct: 317 NRNGGYGCVCVNGWSGDDCS-ENIDDCAFASCTPGSTCIDRVASFSCMCPEG----KAGL 371
Query: 192 NCRDVDECERDTHTCQQICSNT--EGSYECSCEDGYEKRGDACVDINECH--EEGVCPSP 359
C D C + +C G Y C+C GY K D D++EC C
Sbjct: 372 LCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGY-KGADCTEDVDECAMANSNPCEHA 430
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
G+CVN G+F C C +GY G RC +D +EC + CQ A C + GG+ C C G
Sbjct: 431 GKCVNTDGAFHCECLKGY----AGPRCEMDINEC-HSDPCQNDATCLDKIGGFTCLCMPG 485
Score = 77.4 bits (182), Expect = 3e-14
Identities = 57/185 (30%), Positives = 82/185 (44%), Gaps = 12/185 (6%)
Frame = +3
Query: 6 GVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
GVNT F C+C PG+ + +EC P C + SY C C+ G+ D
Sbjct: 929 GVNT---FSCLCLPGFT-GDKYQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGF----D 980
Query: 186 GANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSP 359
G +C + ++EC + C + S+ C C G+ G C+ +INEC C +
Sbjct: 981 GVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFT--GSFCLHEINECSSHP-CLNE 1037
Query: 360 GRCVNLLGSFRCVCPRGY--RLDAEGARCVDRDECAQTGRC-----QAPC---RNYAGGY 509
G CV+ LG++RC CP GY + R C G C ++ C +AG Y
Sbjct: 1038 GTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAY 1097
Query: 510 RCDCP 524
CD P
Sbjct: 1098 -CDVP 1101
Score = 75.8 bits (178), Expect = 1e-13
Identities = 57/186 (30%), Positives = 82/186 (44%), Gaps = 12/186 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
V+ I SF C+C G+ + +EC+ P + C + G+Y C C GY G
Sbjct: 1003 VDGINSFSCLCPVGFT-GSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYT----G 1057
Query: 189 ANCRD-VDECERDTHTCQQICSNTEGSYECSCEDG----YEKRGDACVDINECHE----E 341
NC+ V+ C R + C + +C C G Y + DI E
Sbjct: 1058 KNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVE 1117
Query: 342 GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ--APCRNYAGGYR 512
+C G C+N + C CP GY G+ C ++ DECA + CQ A C ++ GGYR
Sbjct: 1118 HLCQHSGVCINAGNTHYCQCPLGYT----GSYCEEQLDECA-SNPCQHGATCSDFIGGYR 1172
Query: 513 CDCPVG 530
C+C G
Sbjct: 1173 CECVPG 1178
Score = 74.5 bits (175), Expect = 2e-13
Identities = 55/189 (29%), Positives = 75/189 (39%), Gaps = 20/189 (10%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAV-RPPPCDQLCHNTD-GSYDCLCRTGYELDEDGA 191
+G C C G+ C V RP CH +Y+C C+ G+ G
Sbjct: 85 LGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFT----GK 140
Query: 192 NCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
C+ D C +H C C+ + C C G+ G C D+NEC G C G
Sbjct: 141 ECQWTDACL--SHPCANGSTCTTVANQFSCKCLTGFT--GQKCETDVNECDIPGHCQHGG 196
Query: 363 RCVNLLGSFRCVCPRGYR--------LDAEGARCVDRDECAQTGRCQAPCRNYAG--GYR 512
C+NL GS++C CP+G+ + + CV+ C QTG C G G
Sbjct: 197 TCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGST 256
Query: 513 C-----DCP 524
C DCP
Sbjct: 257 CERNIDDCP 265
Score = 74.5 bits (175), Expect = 2e-13
Identities = 55/173 (31%), Positives = 75/173 (43%), Gaps = 5/173 (2%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRD 203
+ C C G+ D C P PC C + SY C+C GY GA C D
Sbjct: 554 YECQCATGFTGV-LCEENIDNCD--PDPCHHGQCQDGIDSYTCICNPGYM----GAICSD 606
Query: 204 -VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNL 377
+DEC C + Y+C+C+ G G C ++ ++C C G C++
Sbjct: 607 QIDECYSSPCLNDGRCIDLVNGYQCNCQPGTS--GVNCEINFDDC-ASNPCIH-GICMDG 662
Query: 378 LGSFRCVCPRGYRLDAEGARC-VDRDECAQTG-RCQAPCRNYAGGYRCDCPVG 530
+ + CVC G+ G RC +D DECA R A C N G+RC CP G
Sbjct: 663 INRYSCVCSPGFT----GQRCNIDIDECASNPCRKGATCINGVNGFRCICPEG 711
Score = 74.1 bits (174), Expect = 3e-13
Identities = 53/180 (29%), Positives = 82/180 (45%), Gaps = 5/180 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ IG F C+C PG++ + +EC P + C + + CLC G+ G
Sbjct: 472 LDKIGGFTCLCMPGFKGVHCELE-INECQSNPCVNNGQCVDKVNRFQCLCPPGF----TG 526
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCPSPG 362
C+ D+D+C C + YEC C G+ G C + I+ C + C G
Sbjct: 527 PVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGF--TGVLCEENIDNC-DPDPC-HHG 582
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRC--QAPCRNYAGGYRCDCPVGT 533
+C + + S+ C+C GY GA C D+ DEC + C C + GY+C+C GT
Sbjct: 583 QCQDGIDSYTCICNPGYM----GAICSDQIDEC-YSSPCLNDGRCIDLVNGYQCNCQPGT 637
Score = 74.1 bits (174), Expect = 3e-13
Identities = 55/173 (31%), Positives = 76/173 (43%), Gaps = 5/173 (2%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
I + CVC PG+ + DECA P C N + C+C G +C
Sbjct: 663 INRYSCVCSPGFTGQRCNI-DIDECASNPCRKGATCINGVNGFRCICPEG----PHHPSC 717
Query: 198 -RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCV 371
V+EC + C+ Y+C C+ G+ G C VD NEC C + G C
Sbjct: 718 YSQVNECLSNP-CIHGNCTGGLSGYKCLCDAGWV--GINCEVDKNECLSNP-CQNGGTCD 773
Query: 372 NLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRC--QAPCRNYAGGYRCDC 521
NL+ +RC C +G++ G C V+ DECA + C Q C + GY C C
Sbjct: 774 NLVNGYRCTCKKGFK----GYNCQVNIDECA-SNPCLNQGTCFDDISGYTCHC 821
Score = 73.7 bits (173), Expect = 4e-13
Identities = 51/181 (28%), Positives = 75/181 (41%), Gaps = 5/181 (2%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
R ++ + ++C C PG + D+CA P +C + Y C+C G+
Sbjct: 621 RCIDLVNGYQCNCQPGTSGVNCEINF-DDCASNPC-IHGICMDGINRYSCVCSPGFT--- 675
Query: 183 DGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCPS 356
G C D+DEC + C N + C C +G +C +NEC
Sbjct: 676 -GQRCNIDIDECASNPCRKGATCINGVNGFRCICPEG--PHHPSCYSQVNECLSNPCIH- 731
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPV 527
G C L ++C+C G+ G C VD++EC + CQ C N GYRC C
Sbjct: 732 -GNCTGGLSGYKCLCDAGW----VGINCEVDKNECL-SNPCQNGGTCDNLVNGYRCTCKK 785
Query: 528 G 530
G
Sbjct: 786 G 786
Score = 71.7 bits (168), Expect = 2e-12
Identities = 47/177 (26%), Positives = 75/177 (42%), Gaps = 3/177 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
VNT G+F C C GY R +EC P D C + G + CLC G++ G
Sbjct: 434 VNTDGAFHCECLKGY-AGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFK----G 488
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
+C +++EC+ + C + ++C C G+ G C +DI++C C +
Sbjct: 489 VHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGF--TGPVCQIDIDDC-SSTPCLNGA 545
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQAPCRNYAGGYRCDCPVG 530
+C++ + C C G+ G C + D C C++ Y C C G
Sbjct: 546 KCIDHPNGYECQCATGF----TGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPG 598
Score = 71.3 bits (167), Expect = 2e-12
Identities = 54/188 (28%), Positives = 80/188 (42%), Gaps = 13/188 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYE---L 176
V+ +G++RC C GY G+ + R P ++ C CLC +G+
Sbjct: 1041 VDGLGTYRCSCPLGY--TGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYC 1098
Query: 177 DEDGANCRDVDECERDT---HTCQQ--ICSNTEGSYECSCEDGYEKRGDACVD-INECHE 338
D +C D+ R H CQ +C N ++ C C GY G C + ++EC
Sbjct: 1099 DVPNVSC-DIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYT--GSYCEEQLDEC-A 1154
Query: 339 EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGY 509
C C + +G +RC C GY +G C + DEC Q CQ C + +
Sbjct: 1155 SNPCQHGATCSDFIGGYRCECVPGY----QGVNCEYEVDEC-QNQPCQNGGTCIDLVNHF 1209
Query: 510 RCDCPVGT 533
+C CP GT
Sbjct: 1210 KCSCPPGT 1217
Score = 70.5 bits (165), Expect = 4e-12
Identities = 54/184 (29%), Positives = 82/184 (44%), Gaps = 10/184 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRD-ECAVRPPPCDQLCHNT-DGSYDCLCRTGYELDE 182
+N GS++C C G+ G+ CA P C T D +++C C G+E
Sbjct: 199 LNLPGSYQCQCPQGF--TGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFE--- 253
Query: 183 DGANC-RDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACV-DINECH-EEGV 347
G+ C R++D+C H CQ +C + +Y C C + G C D++EC +
Sbjct: 254 -GSTCERNIDDCPN--HRCQNGGVCVDGVNTYNCRCPPQWT--GQFCTEDVDECLLQPNA 308
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ--APCRNYAGGYRCD 518
C + G C N G + CVC G+ G C + D+CA C + C + + C
Sbjct: 309 CQNGGTCANRNGGYGCVCVNGW----SGDDCSENIDDCA-FASCTPGSTCIDRVASFSCM 363
Query: 519 CPVG 530
CP G
Sbjct: 364 CPEG 367
Score = 69.7 bits (163), Expect = 6e-12
Identities = 54/180 (30%), Positives = 75/180 (41%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N + +RC C G++ V DECA P C + Y C C Y G
Sbjct: 774 NLVNGYRCTCKKGFKGYNCQVN-IDECASNPCLNQGTCFDDISGYTCHCVLPY----TGK 828
Query: 192 NCRDV-DECERDTHTCQQICSNTEG--SYECSCEDGYEKRGDAC-VDINECHEEGVCPSP 359
NC+ V C + +C + SY C C G++ G C +DI+EC + C +
Sbjct: 829 NCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQ--GQRCTIDIDECISK-PCMNH 885
Query: 360 GRCVNLLGSFRCVCPRGYR-LDAEGARCVDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
G C N GS+ C CP G+ +D E D D+C CQ C + + C C G
Sbjct: 886 GLCHNTQGSYMCECPPGFSGMDCE----EDIDDCL-ANPCQNGGSCMDGVNTFSCLCLPG 940
Score = 62.9 bits (146), Expect = 7e-10
Identities = 33/101 (32%), Positives = 51/101 (50%), Gaps = 2/101 (1%)
Frame = +3
Query: 120 LCHNTDGSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYE 296
+C N ++ C C GY G+ C + +DEC + CS+ G Y C C GY+
Sbjct: 1125 VCINAGNTHYCQCPLGYT----GSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQ 1180
Query: 297 KRGDAC-VDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYR 416
G C +++EC + C + G C++L+ F+C CP G R
Sbjct: 1181 --GVNCEYEVDECQNQP-CQNGGTCIDLVNHFKCSCPPGTR 1218
Score = 56.0 bits (129), Expect = 8e-08
Identities = 33/103 (32%), Positives = 45/103 (43%), Gaps = 3/103 (2%)
Frame = +3
Query: 231 TCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRG 410
TC + +T YEC+C+ G+ G C + C C + C + F C C G
Sbjct: 120 TCHMLSRDT---YECTCQVGFT--GKECQWTDACLSHP-CANGSTCTTVANQFSCKCLTG 173
Query: 411 YRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
+ G +C D +EC G CQ C N G Y+C CP G
Sbjct: 174 FT----GQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQG 212
>AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2
(Drosophila) protein.
Length = 2471
Score = 100 bits (239), Expect = 4e-21
Identities = 60/177 (33%), Positives = 87/177 (49%), Gaps = 7/177 (3%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAV-RPPPCDQL--CHNTDGSYDCLCRTGYELDEDGA 191
G + C C GY+ A DECA+ PC+ C NTDG++ C C GY G
Sbjct: 397 GQYICTCPQGYKGADC-TEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYA----GP 451
Query: 192 NCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGR 365
C D++EC D C + G + C C G+ +G C ++INEC + C + G+
Sbjct: 452 RCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGF--KGVHCELEINEC-QSNPCVNNGQ 508
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ-APCRNYAGGYRCDCPVG 530
CV+ + F+C+CP G+ G C +D D+C+ T A C ++ GY C C G
Sbjct: 509 CVDKVNRFQCLCPPGF----TGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATG 561
Score = 91.1 bits (216), Expect = 2e-18
Identities = 55/173 (31%), Positives = 82/173 (47%), Gaps = 4/173 (2%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-R 200
S+ C+C PG++ R DEC +P LCHNT GSY C C G+ G +C
Sbjct: 856 SYTCLCAPGWQ-GQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGF----SGMDCEE 910
Query: 201 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNL 377
D+D+C + C + ++ C C G+ GD C D+NEC E C + G C +
Sbjct: 911 DIDDCLANPCQNGGSCMDGVNTFSCLCLPGF--TGDKCQTDMNECLSE-PCKNGGTCSDY 967
Query: 378 LGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ-APCRNYAGGYRCDCPVG 530
+ S+ C C G+ +G C + +EC ++ C + + C CPVG
Sbjct: 968 VNSYTCKCQAGF----DGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVG 1016
Score = 88.6 bits (210), Expect = 1e-17
Identities = 59/179 (32%), Positives = 90/179 (50%), Gaps = 6/179 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGV-RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
NT GS+ C C PG+ +G D+C P C + ++ CLC G+ G
Sbjct: 890 NTQGSYMCECPPGF--SGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGF----TG 943
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSPG 362
C+ D++EC + CS+ SY C C+ G++ G C +INEC E C + G
Sbjct: 944 DKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFD--GVHCENNINECTESS-CFNGG 1000
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCV-DRDECAQTGRC--QAPCRNYAGGYRCDCPVG 530
CV+ + SF C+CP G+ G+ C+ + +EC+ + C + C + G YRC CP+G
Sbjct: 1001 TCVDGINSFSCLCPVGF----TGSFCLHEINECS-SHPCLNEGTCVDGLGTYRCSCPLG 1054
Score = 81.8 bits (193), Expect = 1e-15
Identities = 54/176 (30%), Positives = 72/176 (40%), Gaps = 3/176 (1%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
I S+ C+C PGY A + DEC P D C + Y C C+ G G NC
Sbjct: 588 IDSYTCICNPGYMGAICSDQ-IDECYSSPCLNDGRCIDLVNGYQCNCQPG----TSGVNC 642
Query: 198 R-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCV 371
+ D+C + IC + Y C C G+ G C +DI+EC C C+
Sbjct: 643 EINFDDCASNP-CIHGICMDGINRYSCVCSPGFT--GQRCNIDIDEC-ASNPCRKGATCI 698
Query: 372 NLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQAPCRNYAGGYRCDCPVGTV 536
N + FRC+CP G C + +EC C GY+C C G V
Sbjct: 699 NGVNGFRCICPEG----PHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWV 750
Score = 80.6 bits (190), Expect = 3e-15
Identities = 52/177 (29%), Positives = 79/177 (44%), Gaps = 3/177 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
V+ + F+C+C PG+ + D+C+ P C + Y+C C TG+ G
Sbjct: 510 VDKVNRFQCLCPPGFTGPVCQI-DIDDCSSTPCLNGAKCIDHPNGYECQCATGFT----G 564
Query: 189 ANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCPSPG 362
C + +D C+ D Q C + SY C C GY G C D I+EC+ C + G
Sbjct: 565 VLCEENIDNCDPDPCHHGQ-CQDGIDSYTCICNPGY--MGAICSDQIDECYSSP-CLNDG 620
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
RC++L+ ++C C G G C ++ D+CA C + Y C C G
Sbjct: 621 RCIDLVNGYQCNCQPG----TSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPG 673
Score = 77.8 bits (183), Expect = 2e-14
Identities = 56/180 (31%), Positives = 76/180 (42%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N G + CVC G+ D+CA C + S+ C+C G + G
Sbjct: 317 NRNGGYGCVCVNGWSGDDCS-ENIDDCAFASCTPGSTCIDRVASFSCMCPEG----KAGL 371
Query: 192 NCRDVDECERDTHTCQQICSNT--EGSYECSCEDGYEKRGDACVDINECH--EEGVCPSP 359
C D C + +C G Y C+C GY K D D++EC C
Sbjct: 372 LCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGY-KGADCTEDVDECAMANSNPCEHA 430
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
G+CVN G+F C C +GY G RC +D +EC + CQ A C + GG+ C C G
Sbjct: 431 GKCVNTDGAFHCECLKGY----AGPRCEMDINEC-HSDPCQNDATCLDKIGGFTCLCMPG 485
Score = 77.4 bits (182), Expect = 3e-14
Identities = 57/185 (30%), Positives = 82/185 (44%), Gaps = 12/185 (6%)
Frame = +3
Query: 6 GVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
GVNT F C+C PG+ + +EC P C + SY C C+ G+ D
Sbjct: 929 GVNT---FSCLCLPGFT-GDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGF----D 980
Query: 186 GANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSP 359
G +C + ++EC + C + S+ C C G+ G C+ +INEC C +
Sbjct: 981 GVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFT--GSFCLHEINECSSHP-CLNE 1037
Query: 360 GRCVNLLGSFRCVCPRGY--RLDAEGARCVDRDECAQTGRC-----QAPC---RNYAGGY 509
G CV+ LG++RC CP GY + R C G C ++ C +AG Y
Sbjct: 1038 GTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAY 1097
Query: 510 RCDCP 524
CD P
Sbjct: 1098 -CDVP 1101
Score = 77.4 bits (182), Expect = 3e-14
Identities = 46/142 (32%), Positives = 68/142 (47%), Gaps = 5/142 (3%)
Frame = +3
Query: 120 LCHNTDGSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYE 296
+C N ++ C C GY G+ C + +DEC + CS+ G Y C C GY+
Sbjct: 1125 VCINAGNTHYCQCPLGYT----GSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQ 1180
Query: 297 KRGDAC-VDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTG 470
G C +++EC + C + G C++L+ F+C CP G R G C + D+CA+
Sbjct: 1181 --GVNCEYEVDECQNQP-CQNGGTCIDLVNHFKCSCPPGTR----GLLCEENIDDCARGP 1233
Query: 471 RC--QAPCRNYAGGYRCDCPVG 530
C C + GGY C C G
Sbjct: 1234 HCLNGGQCMDRIGGYSCRCLPG 1255
Score = 75.8 bits (178), Expect = 1e-13
Identities = 57/186 (30%), Positives = 82/186 (44%), Gaps = 12/186 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
V+ I SF C+C G+ + +EC+ P + C + G+Y C C GY G
Sbjct: 1003 VDGINSFSCLCPVGFT-GSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYT----G 1057
Query: 189 ANCRD-VDECERDTHTCQQICSNTEGSYECSCEDG----YEKRGDACVDINECHE----E 341
NC+ V+ C R + C + +C C G Y + DI E
Sbjct: 1058 KNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVE 1117
Query: 342 GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ--APCRNYAGGYR 512
+C G C+N + C CP GY G+ C ++ DECA + CQ A C ++ GGYR
Sbjct: 1118 HLCQHSGVCINAGNTHYCQCPLGY----TGSYCEEQLDECA-SNPCQHGATCSDFIGGYR 1172
Query: 513 CDCPVG 530
C+C G
Sbjct: 1173 CECVPG 1178
Score = 74.5 bits (175), Expect = 2e-13
Identities = 55/189 (29%), Positives = 75/189 (39%), Gaps = 20/189 (10%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAV-RPPPCDQLCHNTD-GSYDCLCRTGYELDEDGA 191
+G C C G+ C V RP CH +Y+C C+ G+ G
Sbjct: 85 LGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFT----GK 140
Query: 192 NCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
C+ D C +H C C+ + C C G+ G C D+NEC G C G
Sbjct: 141 ECQWTDACL--SHPCANGSTCTTVANQFSCKCLTGFT--GQKCETDVNECDIPGHCQHGG 196
Query: 363 RCVNLLGSFRCVCPRGYR--------LDAEGARCVDRDECAQTGRCQAPCRNYAG--GYR 512
C+NL GS++C CP+G+ + + CV+ C QTG C G G
Sbjct: 197 TCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGST 256
Query: 513 C-----DCP 524
C DCP
Sbjct: 257 CERNIDDCP 265
Score = 74.5 bits (175), Expect = 2e-13
Identities = 55/173 (31%), Positives = 75/173 (43%), Gaps = 5/173 (2%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRD 203
+ C C G+ D C P PC C + SY C+C GY GA C D
Sbjct: 554 YECQCATGFTGV-LCEENIDNCD--PDPCHHGQCQDGIDSYTCICNPGYM----GAICSD 606
Query: 204 -VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNL 377
+DEC C + Y+C+C+ G G C ++ ++C C G C++
Sbjct: 607 QIDECYSSPCLNDGRCIDLVNGYQCNCQPGTS--GVNCEINFDDC-ASNPCIH-GICMDG 662
Query: 378 LGSFRCVCPRGYRLDAEGARC-VDRDECAQTG-RCQAPCRNYAGGYRCDCPVG 530
+ + CVC G+ G RC +D DECA R A C N G+RC CP G
Sbjct: 663 INRYSCVCSPGFT----GQRCNIDIDECASNPCRKGATCINGVNGFRCICPEG 711
Score = 74.1 bits (174), Expect = 3e-13
Identities = 53/180 (29%), Positives = 82/180 (45%), Gaps = 5/180 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ IG F C+C PG++ + +EC P + C + + CLC G+ G
Sbjct: 472 LDKIGGFTCLCMPGFKGVHCELE-INECQSNPCVNNGQCVDKVNRFQCLCPPGF----TG 526
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCPSPG 362
C+ D+D+C C + YEC C G+ G C + I+ C + C G
Sbjct: 527 PVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGF--TGVLCEENIDNC-DPDPC-HHG 582
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRC--QAPCRNYAGGYRCDCPVGT 533
+C + + S+ C+C GY GA C D+ DEC + C C + GY+C+C GT
Sbjct: 583 QCQDGIDSYTCICNPGYM----GAICSDQIDEC-YSSPCLNDGRCIDLVNGYQCNCQPGT 637
Score = 74.1 bits (174), Expect = 3e-13
Identities = 55/173 (31%), Positives = 76/173 (43%), Gaps = 5/173 (2%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
I + CVC PG+ + DECA P C N + C+C G +C
Sbjct: 663 INRYSCVCSPGFTGQRCNI-DIDECASNPCRKGATCINGVNGFRCICPEG----PHHPSC 717
Query: 198 -RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCV 371
V+EC + C+ Y+C C+ G+ G C VD NEC C + G C
Sbjct: 718 YSQVNECLSNP-CIHGNCTGGLSGYKCLCDAGWV--GINCEVDKNECLSNP-CQNGGTCD 773
Query: 372 NLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRC--QAPCRNYAGGYRCDC 521
NL+ +RC C +G++ G C V+ DECA + C Q C + GY C C
Sbjct: 774 NLVNGYRCTCKKGFK----GYNCQVNIDECA-SNPCLNQGTCFDDISGYTCHC 821
Score = 73.7 bits (173), Expect = 4e-13
Identities = 51/181 (28%), Positives = 75/181 (41%), Gaps = 5/181 (2%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
R ++ + ++C C PG + D+CA P +C + Y C+C G+
Sbjct: 621 RCIDLVNGYQCNCQPGTSGVNCEINF-DDCASNPC-IHGICMDGINRYSCVCSPGFT--- 675
Query: 183 DGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCPS 356
G C D+DEC + C N + C C +G +C +NEC
Sbjct: 676 -GQRCNIDIDECASNPCRKGATCINGVNGFRCICPEG--PHHPSCYSQVNECLSNPCIH- 731
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPV 527
G C L ++C+C G+ G C VD++EC + CQ C N GYRC C
Sbjct: 732 -GNCTGGLSGYKCLCDAGW----VGINCEVDKNECL-SNPCQNGGTCDNLVNGYRCTCKK 785
Query: 528 G 530
G
Sbjct: 786 G 786
Score = 71.7 bits (168), Expect = 2e-12
Identities = 47/177 (26%), Positives = 75/177 (42%), Gaps = 3/177 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
VNT G+F C C GY R +EC P D C + G + CLC G++ G
Sbjct: 434 VNTDGAFHCECLKGY-AGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFK----G 488
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
+C +++EC+ + C + ++C C G+ G C +DI++C C +
Sbjct: 489 VHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGF--TGPVCQIDIDDC-SSTPCLNGA 545
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQAPCRNYAGGYRCDCPVG 530
+C++ + C C G+ G C + D C C++ Y C C G
Sbjct: 546 KCIDHPNGYECQCATGF----TGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPG 598
Score = 71.3 bits (167), Expect = 2e-12
Identities = 54/188 (28%), Positives = 80/188 (42%), Gaps = 13/188 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYE---L 176
V+ +G++RC C GY G+ + R P ++ C CLC +G+
Sbjct: 1041 VDGLGTYRCSCPLGY--TGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYC 1098
Query: 177 DEDGANCRDVDECERDT---HTCQQ--ICSNTEGSYECSCEDGYEKRGDACVD-INECHE 338
D +C D+ R H CQ +C N ++ C C GY G C + ++EC
Sbjct: 1099 DVPNVSC-DIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYT--GSYCEEQLDEC-A 1154
Query: 339 EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGY 509
C C + +G +RC C GY +G C + DEC Q CQ C + +
Sbjct: 1155 SNPCQHGATCSDFIGGYRCECVPGY----QGVNCEYEVDEC-QNQPCQNGGTCIDLVNHF 1209
Query: 510 RCDCPVGT 533
+C CP GT
Sbjct: 1210 KCSCPPGT 1217
Score = 70.5 bits (165), Expect = 4e-12
Identities = 54/184 (29%), Positives = 82/184 (44%), Gaps = 10/184 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRD-ECAVRPPPCDQLCHNT-DGSYDCLCRTGYELDE 182
+N GS++C C G+ G+ CA P C T D +++C C G+E
Sbjct: 199 LNLPGSYQCQCPQGF--TGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFE--- 253
Query: 183 DGANC-RDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACV-DINECH-EEGV 347
G+ C R++D+C H CQ +C + +Y C C + G C D++EC +
Sbjct: 254 -GSTCERNIDDCPN--HRCQNGGVCVDGVNTYNCRCPPQWT--GQFCTEDVDECLLQPNA 308
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ--APCRNYAGGYRCD 518
C + G C N G + CVC G+ G C + D+CA C + C + + C
Sbjct: 309 CQNGGTCANRNGGYGCVCVNGW----SGDDCSENIDDCA-FASCTPGSTCIDRVASFSCM 363
Query: 519 CPVG 530
CP G
Sbjct: 364 CPEG 367
Score = 69.7 bits (163), Expect = 6e-12
Identities = 54/180 (30%), Positives = 75/180 (41%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N + +RC C G++ V DECA P C + Y C C Y G
Sbjct: 774 NLVNGYRCTCKKGFKGYNCQVN-IDECASNPCLNQGTCFDDISGYTCHCVLPY----TGK 828
Query: 192 NCRDV-DECERDTHTCQQICSNTEG--SYECSCEDGYEKRGDAC-VDINECHEEGVCPSP 359
NC+ V C + +C + SY C C G++ G C +DI+EC + C +
Sbjct: 829 NCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQ--GQRCTIDIDECISK-PCMNH 885
Query: 360 GRCVNLLGSFRCVCPRGYR-LDAEGARCVDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
G C N GS+ C CP G+ +D E D D+C CQ C + + C C G
Sbjct: 886 GLCHNTQGSYMCECPPGFSGMDCE----EDIDDCL-ANPCQNGGSCMDGVNTFSCLCLPG 940
Score = 69.7 bits (163), Expect = 6e-12
Identities = 51/177 (28%), Positives = 72/177 (40%), Gaps = 6/177 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+N + C C GY DECA P C + G Y C C GY+ G
Sbjct: 1127 INAGNTHYCQCPLGYT-GSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQ----G 1181
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCPSPG 362
NC +VDEC+ C + ++CSC G RG C + I++C C + G
Sbjct: 1182 VNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPG--TRGLLCEENIDDCARGPHCLNGG 1239
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCV-DRDECAQ---TGRCQAPCRNYAGGYRCDC 521
+C++ +G + C C G+ G RC D +EC + C Y C C
Sbjct: 1240 QCMDRIGGYSCRCLPGF----AGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVC 1292
Score = 56.0 bits (129), Expect = 8e-08
Identities = 33/103 (32%), Positives = 45/103 (43%), Gaps = 3/103 (2%)
Frame = +3
Query: 231 TCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRG 410
TC + +T YEC+C+ G+ G C + C C + C + F C C G
Sbjct: 120 TCHMLSRDT---YECTCQVGFT--GKECQWTDACLSHP-CANGSTCTTVANQFSCKCLTG 173
Query: 411 YRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
+ G +C D +EC G CQ C N G Y+C CP G
Sbjct: 174 FT----GQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQG 212
Score = 45.6 bits (103), Expect = 1e-04
Identities = 50/179 (27%), Positives = 69/179 (38%), Gaps = 8/179 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGR-DECAVRPPPCDQL--CHNTDGSYDCLCRTGYELD 179
++ IG + C C PG+ AG G +EC P + C Y C+CR+ +
Sbjct: 1242 MDRIGGYSCRCLPGF--AGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFT-- 1297
Query: 180 EDGANCRD-VDECER----DTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEG 344
G +C VD C + + TC + SN + C C G+ G C + C +
Sbjct: 1298 --GRHCETFVDVCPQMPCLNGGTCA-VASNMPDGFICRCPPGFS--GARCQ--SSCGQVK 1350
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
C +CV+ RC CP D E C C G C P R Y C C
Sbjct: 1351 -CRKGEQCVHTASGPRCFCPS--PRDCESG-CAS-SPCQHGGSCH-PQRQ-PPYYSCQC 1402
>AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2
(Drosophila) protein.
Length = 2471
Score = 100 bits (239), Expect = 4e-21
Identities = 60/177 (33%), Positives = 87/177 (49%), Gaps = 7/177 (3%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAV-RPPPCDQL--CHNTDGSYDCLCRTGYELDEDGA 191
G + C C GY+ A DECA+ PC+ C NTDG++ C C GY G
Sbjct: 397 GQYICTCPQGYKGADC-TEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYA----GP 451
Query: 192 NCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGR 365
C D++EC D C + G + C C G+ +G C ++INEC + C + G+
Sbjct: 452 RCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGF--KGVHCELEINEC-QSNPCVNNGQ 508
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ-APCRNYAGGYRCDCPVG 530
CV+ + F+C+CP G+ G C +D D+C+ T A C ++ GY C C G
Sbjct: 509 CVDKVNRFQCLCPPGF----TGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATG 561
Score = 91.1 bits (216), Expect = 2e-18
Identities = 55/173 (31%), Positives = 82/173 (47%), Gaps = 4/173 (2%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-R 200
S+ C+C PG++ R DEC +P LCHNT GSY C C G+ G +C
Sbjct: 856 SYTCLCAPGWQ-GQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGF----SGMDCEE 910
Query: 201 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNL 377
D+D+C + C + ++ C C G+ GD C D+NEC E C + G C +
Sbjct: 911 DIDDCLANPCQNGGSCMDGVNTFSCLCLPGF--TGDKCQTDMNECLSE-PCKNGGTCSDY 967
Query: 378 LGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ-APCRNYAGGYRCDCPVG 530
+ S+ C C G+ +G C + +EC ++ C + + C CPVG
Sbjct: 968 VNSYTCKCQAGF----DGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVG 1016
Score = 88.6 bits (210), Expect = 1e-17
Identities = 59/179 (32%), Positives = 90/179 (50%), Gaps = 6/179 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGV-RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
NT GS+ C C PG+ +G D+C P C + ++ CLC G+ G
Sbjct: 890 NTQGSYMCECPPGF--SGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGF----TG 943
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSPG 362
C+ D++EC + CS+ SY C C+ G++ G C +INEC E C + G
Sbjct: 944 DKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFD--GVHCENNINECTESS-CFNGG 1000
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCV-DRDECAQTGRC--QAPCRNYAGGYRCDCPVG 530
CV+ + SF C+CP G+ G+ C+ + +EC+ + C + C + G YRC CP+G
Sbjct: 1001 TCVDGINSFSCLCPVGF----TGSFCLHEINECS-SHPCLNEGTCVDGLGTYRCSCPLG 1054
Score = 81.8 bits (193), Expect = 1e-15
Identities = 54/176 (30%), Positives = 72/176 (40%), Gaps = 3/176 (1%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
I S+ C+C PGY A + DEC P D C + Y C C+ G G NC
Sbjct: 588 IDSYTCICNPGYMGAICSDQ-IDECYSSPCLNDGRCIDLVNGYQCNCQPG----TSGVNC 642
Query: 198 R-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCV 371
+ D+C + IC + Y C C G+ G C +DI+EC C C+
Sbjct: 643 EINFDDCASNP-CIHGICMDGINRYSCVCSPGFT--GQRCNIDIDEC-ASNPCRKGATCI 698
Query: 372 NLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQAPCRNYAGGYRCDCPVGTV 536
N + FRC+CP G C + +EC C GY+C C G V
Sbjct: 699 NGVNGFRCICPEG----PHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWV 750
Score = 80.6 bits (190), Expect = 3e-15
Identities = 52/177 (29%), Positives = 79/177 (44%), Gaps = 3/177 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
V+ + F+C+C PG+ + D+C+ P C + Y+C C TG+ G
Sbjct: 510 VDKVNRFQCLCPPGFTGPVCQI-DIDDCSSTPCLNGAKCIDHPNGYECQCATGFT----G 564
Query: 189 ANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCPSPG 362
C + +D C+ D Q C + SY C C GY G C D I+EC+ C + G
Sbjct: 565 VLCEENIDNCDPDPCHHGQ-CQDGIDSYTCICNPGY--MGAICSDQIDECYSSP-CLNDG 620
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
RC++L+ ++C C G G C ++ D+CA C + Y C C G
Sbjct: 621 RCIDLVNGYQCNCQPG----TSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPG 673
Score = 77.8 bits (183), Expect = 2e-14
Identities = 56/180 (31%), Positives = 76/180 (42%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N G + CVC G+ D+CA C + S+ C+C G + G
Sbjct: 317 NRNGGYGCVCVNGWSGDDCS-ENIDDCAFASCTPGSTCIDRVASFSCMCPEG----KAGL 371
Query: 192 NCRDVDECERDTHTCQQICSNT--EGSYECSCEDGYEKRGDACVDINECH--EEGVCPSP 359
C D C + +C G Y C+C GY K D D++EC C
Sbjct: 372 LCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGY-KGADCTEDVDECAMANSNPCEHA 430
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
G+CVN G+F C C +GY G RC +D +EC + CQ A C + GG+ C C G
Sbjct: 431 GKCVNTDGAFHCECLKGY----AGPRCEMDINEC-HSDPCQNDATCLDKIGGFTCLCMPG 485
Score = 77.4 bits (182), Expect = 3e-14
Identities = 57/185 (30%), Positives = 82/185 (44%), Gaps = 12/185 (6%)
Frame = +3
Query: 6 GVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
GVNT F C+C PG+ + +EC P C + SY C C+ G+ D
Sbjct: 929 GVNT---FSCLCLPGFT-GDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGF----D 980
Query: 186 GANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSP 359
G +C + ++EC + C + S+ C C G+ G C+ +INEC C +
Sbjct: 981 GVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFT--GSFCLHEINECSSHP-CLNE 1037
Query: 360 GRCVNLLGSFRCVCPRGY--RLDAEGARCVDRDECAQTGRC-----QAPC---RNYAGGY 509
G CV+ LG++RC CP GY + R C G C ++ C +AG Y
Sbjct: 1038 GTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAY 1097
Query: 510 RCDCP 524
CD P
Sbjct: 1098 -CDVP 1101
Score = 77.4 bits (182), Expect = 3e-14
Identities = 46/142 (32%), Positives = 68/142 (47%), Gaps = 5/142 (3%)
Frame = +3
Query: 120 LCHNTDGSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYE 296
+C N ++ C C GY G+ C + +DEC + CS+ G Y C C GY+
Sbjct: 1125 VCINAGNTHYCQCPLGYT----GSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQ 1180
Query: 297 KRGDAC-VDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTG 470
G C +++EC + C + G C++L+ F+C CP G R G C + D+CA+
Sbjct: 1181 --GVNCEYEVDECQNQP-CQNGGTCIDLVNHFKCSCPPGTR----GLLCEENIDDCARGP 1233
Query: 471 RC--QAPCRNYAGGYRCDCPVG 530
C C + GGY C C G
Sbjct: 1234 HCLNGGQCMDRIGGYSCRCLPG 1255
Score = 75.8 bits (178), Expect = 1e-13
Identities = 57/186 (30%), Positives = 82/186 (44%), Gaps = 12/186 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
V+ I SF C+C G+ + +EC+ P + C + G+Y C C GY G
Sbjct: 1003 VDGINSFSCLCPVGFT-GSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYT----G 1057
Query: 189 ANCRD-VDECERDTHTCQQICSNTEGSYECSCEDG----YEKRGDACVDINECHE----E 341
NC+ V+ C R + C + +C C G Y + DI E
Sbjct: 1058 KNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVE 1117
Query: 342 GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ--APCRNYAGGYR 512
+C G C+N + C CP GY G+ C ++ DECA + CQ A C ++ GGYR
Sbjct: 1118 HLCQHSGVCINAGNTHYCQCPLGY----TGSYCEEQLDECA-SNPCQHGATCSDFIGGYR 1172
Query: 513 CDCPVG 530
C+C G
Sbjct: 1173 CECVPG 1178
Score = 74.5 bits (175), Expect = 2e-13
Identities = 55/189 (29%), Positives = 75/189 (39%), Gaps = 20/189 (10%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAV-RPPPCDQLCHNTD-GSYDCLCRTGYELDEDGA 191
+G C C G+ C V RP CH +Y+C C+ G+ G
Sbjct: 85 LGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFT----GK 140
Query: 192 NCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
C+ D C +H C C+ + C C G+ G C D+NEC G C G
Sbjct: 141 ECQWTDACL--SHPCANGSTCTTVANQFSCKCLTGFT--GQKCETDVNECDIPGHCQHGG 196
Query: 363 RCVNLLGSFRCVCPRGYR--------LDAEGARCVDRDECAQTGRCQAPCRNYAG--GYR 512
C+NL GS++C CP+G+ + + CV+ C QTG C G G
Sbjct: 197 TCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGST 256
Query: 513 C-----DCP 524
C DCP
Sbjct: 257 CERNIDDCP 265
Score = 74.5 bits (175), Expect = 2e-13
Identities = 55/173 (31%), Positives = 75/173 (43%), Gaps = 5/173 (2%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRD 203
+ C C G+ D C P PC C + SY C+C GY GA C D
Sbjct: 554 YECQCATGFTGV-LCEENIDNCD--PDPCHHGQCQDGIDSYTCICNPGYM----GAICSD 606
Query: 204 -VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNL 377
+DEC C + Y+C+C+ G G C ++ ++C C G C++
Sbjct: 607 QIDECYSSPCLNDGRCIDLVNGYQCNCQPGTS--GVNCEINFDDC-ASNPCIH-GICMDG 662
Query: 378 LGSFRCVCPRGYRLDAEGARC-VDRDECAQTG-RCQAPCRNYAGGYRCDCPVG 530
+ + CVC G+ G RC +D DECA R A C N G+RC CP G
Sbjct: 663 INRYSCVCSPGFT----GQRCNIDIDECASNPCRKGATCINGVNGFRCICPEG 711
Score = 74.1 bits (174), Expect = 3e-13
Identities = 53/180 (29%), Positives = 82/180 (45%), Gaps = 5/180 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ IG F C+C PG++ + +EC P + C + + CLC G+ G
Sbjct: 472 LDKIGGFTCLCMPGFKGVHCELE-INECQSNPCVNNGQCVDKVNRFQCLCPPGF----TG 526
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCPSPG 362
C+ D+D+C C + YEC C G+ G C + I+ C + C G
Sbjct: 527 PVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGF--TGVLCEENIDNC-DPDPC-HHG 582
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRC--QAPCRNYAGGYRCDCPVGT 533
+C + + S+ C+C GY GA C D+ DEC + C C + GY+C+C GT
Sbjct: 583 QCQDGIDSYTCICNPGYM----GAICSDQIDEC-YSSPCLNDGRCIDLVNGYQCNCQPGT 637
Score = 74.1 bits (174), Expect = 3e-13
Identities = 55/173 (31%), Positives = 76/173 (43%), Gaps = 5/173 (2%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
I + CVC PG+ + DECA P C N + C+C G +C
Sbjct: 663 INRYSCVCSPGFTGQRCNI-DIDECASNPCRKGATCINGVNGFRCICPEG----PHHPSC 717
Query: 198 -RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCV 371
V+EC + C+ Y+C C+ G+ G C VD NEC C + G C
Sbjct: 718 YSQVNECLSNP-CIHGNCTGGLSGYKCLCDAGWV--GINCEVDKNECLSNP-CQNGGTCD 773
Query: 372 NLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRC--QAPCRNYAGGYRCDC 521
NL+ +RC C +G++ G C V+ DECA + C Q C + GY C C
Sbjct: 774 NLVNGYRCTCKKGFK----GYNCQVNIDECA-SNPCLNQGTCFDDISGYTCHC 821
Score = 73.7 bits (173), Expect = 4e-13
Identities = 51/181 (28%), Positives = 75/181 (41%), Gaps = 5/181 (2%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
R ++ + ++C C PG + D+CA P +C + Y C+C G+
Sbjct: 621 RCIDLVNGYQCNCQPGTSGVNCEINF-DDCASNPC-IHGICMDGINRYSCVCSPGFT--- 675
Query: 183 DGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCPS 356
G C D+DEC + C N + C C +G +C +NEC
Sbjct: 676 -GQRCNIDIDECASNPCRKGATCINGVNGFRCICPEG--PHHPSCYSQVNECLSNPCIH- 731
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPV 527
G C L ++C+C G+ G C VD++EC + CQ C N GYRC C
Sbjct: 732 -GNCTGGLSGYKCLCDAGW----VGINCEVDKNECL-SNPCQNGGTCDNLVNGYRCTCKK 785
Query: 528 G 530
G
Sbjct: 786 G 786
Score = 71.7 bits (168), Expect = 2e-12
Identities = 47/177 (26%), Positives = 75/177 (42%), Gaps = 3/177 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
VNT G+F C C GY R +EC P D C + G + CLC G++ G
Sbjct: 434 VNTDGAFHCECLKGY-AGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFK----G 488
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
+C +++EC+ + C + ++C C G+ G C +DI++C C +
Sbjct: 489 VHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGF--TGPVCQIDIDDC-SSTPCLNGA 545
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQAPCRNYAGGYRCDCPVG 530
+C++ + C C G+ G C + D C C++ Y C C G
Sbjct: 546 KCIDHPNGYECQCATGF----TGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPG 598
Score = 71.3 bits (167), Expect = 2e-12
Identities = 54/188 (28%), Positives = 80/188 (42%), Gaps = 13/188 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYE---L 176
V+ +G++RC C GY G+ + R P ++ C CLC +G+
Sbjct: 1041 VDGLGTYRCSCPLGY--TGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYC 1098
Query: 177 DEDGANCRDVDECERDT---HTCQQ--ICSNTEGSYECSCEDGYEKRGDACVD-INECHE 338
D +C D+ R H CQ +C N ++ C C GY G C + ++EC
Sbjct: 1099 DVPNVSC-DIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYT--GSYCEEQLDEC-A 1154
Query: 339 EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGY 509
C C + +G +RC C GY +G C + DEC Q CQ C + +
Sbjct: 1155 SNPCQHGATCSDFIGGYRCECVPGY----QGVNCEYEVDEC-QNQPCQNGGTCIDLVNHF 1209
Query: 510 RCDCPVGT 533
+C CP GT
Sbjct: 1210 KCSCPPGT 1217
Score = 70.5 bits (165), Expect = 4e-12
Identities = 54/184 (29%), Positives = 82/184 (44%), Gaps = 10/184 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRD-ECAVRPPPCDQLCHNT-DGSYDCLCRTGYELDE 182
+N GS++C C G+ G+ CA P C T D +++C C G+E
Sbjct: 199 LNLPGSYQCQCPQGF--TGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFE--- 253
Query: 183 DGANC-RDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACV-DINECH-EEGV 347
G+ C R++D+C H CQ +C + +Y C C + G C D++EC +
Sbjct: 254 -GSTCERNIDDCPN--HRCQNGGVCVDGVNTYNCRCPPQWT--GQFCTEDVDECLLQPNA 308
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ--APCRNYAGGYRCD 518
C + G C N G + CVC G+ G C + D+CA C + C + + C
Sbjct: 309 CQNGGTCANRNGGYGCVCVNGW----SGDDCSENIDDCA-FASCTPGSTCIDRVASFSCM 363
Query: 519 CPVG 530
CP G
Sbjct: 364 CPEG 367
Score = 69.7 bits (163), Expect = 6e-12
Identities = 54/180 (30%), Positives = 75/180 (41%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N + +RC C G++ V DECA P C + Y C C Y G
Sbjct: 774 NLVNGYRCTCKKGFKGYNCQVN-IDECASNPCLNQGTCFDDISGYTCHCVLPY----TGK 828
Query: 192 NCRDV-DECERDTHTCQQICSNTEG--SYECSCEDGYEKRGDAC-VDINECHEEGVCPSP 359
NC+ V C + +C + SY C C G++ G C +DI+EC + C +
Sbjct: 829 NCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQ--GQRCTIDIDECISK-PCMNH 885
Query: 360 GRCVNLLGSFRCVCPRGYR-LDAEGARCVDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
G C N GS+ C CP G+ +D E D D+C CQ C + + C C G
Sbjct: 886 GLCHNTQGSYMCECPPGFSGMDCE----EDIDDCL-ANPCQNGGSCMDGVNTFSCLCLPG 940
Score = 69.7 bits (163), Expect = 6e-12
Identities = 51/177 (28%), Positives = 72/177 (40%), Gaps = 6/177 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+N + C C GY DECA P C + G Y C C GY+ G
Sbjct: 1127 INAGNTHYCQCPLGYT-GSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQ----G 1181
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCPSPG 362
NC +VDEC+ C + ++CSC G RG C + I++C C + G
Sbjct: 1182 VNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPG--TRGLLCEENIDDCARGPHCLNGG 1239
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCV-DRDECAQ---TGRCQAPCRNYAGGYRCDC 521
+C++ +G + C C G+ G RC D +EC + C Y C C
Sbjct: 1240 QCMDRIGGYSCRCLPGF----AGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVC 1292
Score = 56.0 bits (129), Expect = 8e-08
Identities = 33/103 (32%), Positives = 45/103 (43%), Gaps = 3/103 (2%)
Frame = +3
Query: 231 TCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRG 410
TC + +T YEC+C+ G+ G C + C C + C + F C C G
Sbjct: 120 TCHMLSRDT---YECTCQVGFT--GKECQWTDACLSHP-CANGSTCTTVANQFSCKCLTG 173
Query: 411 YRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
+ G +C D +EC G CQ C N G Y+C CP G
Sbjct: 174 FT----GQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQG 212
Score = 45.6 bits (103), Expect = 1e-04
Identities = 50/179 (27%), Positives = 69/179 (38%), Gaps = 8/179 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGR-DECAVRPPPCDQL--CHNTDGSYDCLCRTGYELD 179
++ IG + C C PG+ AG G +EC P + C Y C+CR+ +
Sbjct: 1242 MDRIGGYSCRCLPGF--AGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFT-- 1297
Query: 180 EDGANCRD-VDECER----DTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEG 344
G +C VD C + + TC + SN + C C G+ G C + C +
Sbjct: 1298 --GRHCETFVDVCPQMPCLNGGTCA-VASNMPDGFICRCPPGFS--GARCQ--SSCGQVK 1350
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
C +CV+ RC CP D E C C G C P R Y C C
Sbjct: 1351 -CRKGEQCVHTASGPRCFCPS--PRDCESG-CAS-SPCQHGGSCH-PQRQ-PPYYSCQC 1402
>AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2
(Drosophila) protein.
Length = 2471
Score = 100 bits (239), Expect = 4e-21
Identities = 60/177 (33%), Positives = 87/177 (49%), Gaps = 7/177 (3%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAV-RPPPCDQL--CHNTDGSYDCLCRTGYELDEDGA 191
G + C C GY+ A DECA+ PC+ C NTDG++ C C GY G
Sbjct: 397 GQYICTCPQGYKGADC-TEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYA----GP 451
Query: 192 NCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGR 365
C D++EC D C + G + C C G+ +G C ++INEC + C + G+
Sbjct: 452 RCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGF--KGVHCELEINEC-QSNPCVNNGQ 508
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ-APCRNYAGGYRCDCPVG 530
CV+ + F+C+CP G+ G C +D D+C+ T A C ++ GY C C G
Sbjct: 509 CVDKVNRFQCLCPPGF----TGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATG 561
Score = 91.1 bits (216), Expect = 2e-18
Identities = 55/173 (31%), Positives = 82/173 (47%), Gaps = 4/173 (2%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-R 200
S+ C+C PG++ R DEC +P LCHNT GSY C C G+ G +C
Sbjct: 856 SYTCLCAPGWQ-GQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGF----SGMDCEE 910
Query: 201 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNL 377
D+D+C + C + ++ C C G+ GD C D+NEC E C + G C +
Sbjct: 911 DIDDCLANPCQNGGSCMDGVNTFSCLCLPGF--TGDKCQTDMNECLSE-PCKNGGTCSDY 967
Query: 378 LGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ-APCRNYAGGYRCDCPVG 530
+ S+ C C G+ +G C + +EC ++ C + + C CPVG
Sbjct: 968 VNSYTCKCQAGF----DGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVG 1016
Score = 88.6 bits (210), Expect = 1e-17
Identities = 59/179 (32%), Positives = 90/179 (50%), Gaps = 6/179 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGV-RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
NT GS+ C C PG+ +G D+C P C + ++ CLC G+ G
Sbjct: 890 NTQGSYMCECPPGF--SGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGF----TG 943
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSPG 362
C+ D++EC + CS+ SY C C+ G++ G C +INEC E C + G
Sbjct: 944 DKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFD--GVHCENNINECTESS-CFNGG 1000
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCV-DRDECAQTGRC--QAPCRNYAGGYRCDCPVG 530
CV+ + SF C+CP G+ G+ C+ + +EC+ + C + C + G YRC CP+G
Sbjct: 1001 TCVDGINSFSCLCPVGF----TGSFCLHEINECS-SHPCLNEGTCVDGLGTYRCSCPLG 1054
Score = 81.8 bits (193), Expect = 1e-15
Identities = 54/176 (30%), Positives = 72/176 (40%), Gaps = 3/176 (1%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
I S+ C+C PGY A + DEC P D C + Y C C+ G G NC
Sbjct: 588 IDSYTCICNPGYMGAICSDQ-IDECYSSPCLNDGRCIDLVNGYQCNCQPG----TSGVNC 642
Query: 198 R-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCV 371
+ D+C + IC + Y C C G+ G C +DI+EC C C+
Sbjct: 643 EINFDDCASNP-CIHGICMDGINRYSCVCSPGFT--GQRCNIDIDEC-ASNPCRKGATCI 698
Query: 372 NLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQAPCRNYAGGYRCDCPVGTV 536
N + FRC+CP G C + +EC C GY+C C G V
Sbjct: 699 NGVNGFRCICPEG----PHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWV 750
Score = 80.6 bits (190), Expect = 3e-15
Identities = 52/177 (29%), Positives = 79/177 (44%), Gaps = 3/177 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
V+ + F+C+C PG+ + D+C+ P C + Y+C C TG+ G
Sbjct: 510 VDKVNRFQCLCPPGFTGPVCQI-DIDDCSSTPCLNGAKCIDHPNGYECQCATGFT----G 564
Query: 189 ANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCPSPG 362
C + +D C+ D Q C + SY C C GY G C D I+EC+ C + G
Sbjct: 565 VLCEENIDNCDPDPCHHGQ-CQDGIDSYTCICNPGY--MGAICSDQIDECYSSP-CLNDG 620
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
RC++L+ ++C C G G C ++ D+CA C + Y C C G
Sbjct: 621 RCIDLVNGYQCNCQPG----TSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPG 673
Score = 77.8 bits (183), Expect = 2e-14
Identities = 56/180 (31%), Positives = 76/180 (42%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N G + CVC G+ D+CA C + S+ C+C G + G
Sbjct: 317 NRNGGYGCVCVNGWSGDDCS-ENIDDCAFASCTPGSTCIDRVASFSCMCPEG----KAGL 371
Query: 192 NCRDVDECERDTHTCQQICSNT--EGSYECSCEDGYEKRGDACVDINECH--EEGVCPSP 359
C D C + +C G Y C+C GY K D D++EC C
Sbjct: 372 LCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGY-KGADCTEDVDECAMANSNPCEHA 430
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
G+CVN G+F C C +GY G RC +D +EC + CQ A C + GG+ C C G
Sbjct: 431 GKCVNTDGAFHCECLKGY----AGPRCEMDINEC-HSDPCQNDATCLDKIGGFTCLCMPG 485
Score = 77.4 bits (182), Expect = 3e-14
Identities = 57/185 (30%), Positives = 82/185 (44%), Gaps = 12/185 (6%)
Frame = +3
Query: 6 GVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
GVNT F C+C PG+ + +EC P C + SY C C+ G+ D
Sbjct: 929 GVNT---FSCLCLPGFT-GDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGF----D 980
Query: 186 GANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSP 359
G +C + ++EC + C + S+ C C G+ G C+ +INEC C +
Sbjct: 981 GVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFT--GSFCLHEINECSSHP-CLNE 1037
Query: 360 GRCVNLLGSFRCVCPRGY--RLDAEGARCVDRDECAQTGRC-----QAPC---RNYAGGY 509
G CV+ LG++RC CP GY + R C G C ++ C +AG Y
Sbjct: 1038 GTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAY 1097
Query: 510 RCDCP 524
CD P
Sbjct: 1098 -CDVP 1101
Score = 77.4 bits (182), Expect = 3e-14
Identities = 46/142 (32%), Positives = 68/142 (47%), Gaps = 5/142 (3%)
Frame = +3
Query: 120 LCHNTDGSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYE 296
+C N ++ C C GY G+ C + +DEC + CS+ G Y C C GY+
Sbjct: 1125 VCINAGNTHYCQCPLGYT----GSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQ 1180
Query: 297 KRGDAC-VDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTG 470
G C +++EC + C + G C++L+ F+C CP G R G C + D+CA+
Sbjct: 1181 --GVNCEYEVDECQNQP-CQNGGTCIDLVNHFKCSCPPGTR----GLLCEENIDDCARGP 1233
Query: 471 RC--QAPCRNYAGGYRCDCPVG 530
C C + GGY C C G
Sbjct: 1234 HCLNGGQCMDRIGGYSCRCLPG 1255
Score = 75.8 bits (178), Expect = 1e-13
Identities = 57/186 (30%), Positives = 82/186 (44%), Gaps = 12/186 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
V+ I SF C+C G+ + +EC+ P + C + G+Y C C GY G
Sbjct: 1003 VDGINSFSCLCPVGFT-GSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYT----G 1057
Query: 189 ANCRD-VDECERDTHTCQQICSNTEGSYECSCEDG----YEKRGDACVDINECHE----E 341
NC+ V+ C R + C + +C C G Y + DI E
Sbjct: 1058 KNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVE 1117
Query: 342 GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ--APCRNYAGGYR 512
+C G C+N + C CP GY G+ C ++ DECA + CQ A C ++ GGYR
Sbjct: 1118 HLCQHSGVCINAGNTHYCQCPLGY----TGSYCEEQLDECA-SNPCQHGATCSDFIGGYR 1172
Query: 513 CDCPVG 530
C+C G
Sbjct: 1173 CECVPG 1178
Score = 74.5 bits (175), Expect = 2e-13
Identities = 55/189 (29%), Positives = 75/189 (39%), Gaps = 20/189 (10%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAV-RPPPCDQLCHNTD-GSYDCLCRTGYELDEDGA 191
+G C C G+ C V RP CH +Y+C C+ G+ G
Sbjct: 85 LGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFT----GK 140
Query: 192 NCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
C+ D C +H C C+ + C C G+ G C D+NEC G C G
Sbjct: 141 ECQWTDACL--SHPCANGSTCTTVANQFSCKCLTGFT--GQKCETDVNECDIPGHCQHGG 196
Query: 363 RCVNLLGSFRCVCPRGYR--------LDAEGARCVDRDECAQTGRCQAPCRNYAG--GYR 512
C+NL GS++C CP+G+ + + CV+ C QTG C G G
Sbjct: 197 TCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGST 256
Query: 513 C-----DCP 524
C DCP
Sbjct: 257 CERNIDDCP 265
Score = 74.5 bits (175), Expect = 2e-13
Identities = 55/173 (31%), Positives = 75/173 (43%), Gaps = 5/173 (2%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRD 203
+ C C G+ D C P PC C + SY C+C GY GA C D
Sbjct: 554 YECQCATGFTGV-LCEENIDNCD--PDPCHHGQCQDGIDSYTCICNPGYM----GAICSD 606
Query: 204 -VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNL 377
+DEC C + Y+C+C+ G G C ++ ++C C G C++
Sbjct: 607 QIDECYSSPCLNDGRCIDLVNGYQCNCQPGTS--GVNCEINFDDC-ASNPCIH-GICMDG 662
Query: 378 LGSFRCVCPRGYRLDAEGARC-VDRDECAQTG-RCQAPCRNYAGGYRCDCPVG 530
+ + CVC G+ G RC +D DECA R A C N G+RC CP G
Sbjct: 663 INRYSCVCSPGFT----GQRCNIDIDECASNPCRKGATCINGVNGFRCICPEG 711
Score = 74.1 bits (174), Expect = 3e-13
Identities = 53/180 (29%), Positives = 82/180 (45%), Gaps = 5/180 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ IG F C+C PG++ + +EC P + C + + CLC G+ G
Sbjct: 472 LDKIGGFTCLCMPGFKGVHCELE-INECQSNPCVNNGQCVDKVNRFQCLCPPGF----TG 526
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCPSPG 362
C+ D+D+C C + YEC C G+ G C + I+ C + C G
Sbjct: 527 PVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGF--TGVLCEENIDNC-DPDPC-HHG 582
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRC--QAPCRNYAGGYRCDCPVGT 533
+C + + S+ C+C GY GA C D+ DEC + C C + GY+C+C GT
Sbjct: 583 QCQDGIDSYTCICNPGYM----GAICSDQIDEC-YSSPCLNDGRCIDLVNGYQCNCQPGT 637
Score = 74.1 bits (174), Expect = 3e-13
Identities = 55/173 (31%), Positives = 76/173 (43%), Gaps = 5/173 (2%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
I + CVC PG+ + DECA P C N + C+C G +C
Sbjct: 663 INRYSCVCSPGFTGQRCNI-DIDECASNPCRKGATCINGVNGFRCICPEG----PHHPSC 717
Query: 198 -RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCV 371
V+EC + C+ Y+C C+ G+ G C VD NEC C + G C
Sbjct: 718 YSQVNECLSNP-CIHGNCTGGLSGYKCLCDAGWV--GINCEVDKNECLSNP-CQNGGTCD 773
Query: 372 NLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRC--QAPCRNYAGGYRCDC 521
NL+ +RC C +G++ G C V+ DECA + C Q C + GY C C
Sbjct: 774 NLVNGYRCTCKKGFK----GYNCQVNIDECA-SNPCLNQGTCFDDISGYTCHC 821
Score = 73.7 bits (173), Expect = 4e-13
Identities = 51/181 (28%), Positives = 75/181 (41%), Gaps = 5/181 (2%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
R ++ + ++C C PG + D+CA P +C + Y C+C G+
Sbjct: 621 RCIDLVNGYQCNCQPGTSGVNCEINF-DDCASNPC-IHGICMDGINRYSCVCSPGFT--- 675
Query: 183 DGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCPS 356
G C D+DEC + C N + C C +G +C +NEC
Sbjct: 676 -GQRCNIDIDECASNPCRKGATCINGVNGFRCICPEG--PHHPSCYSQVNECLSNPCIH- 731
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPV 527
G C L ++C+C G+ G C VD++EC + CQ C N GYRC C
Sbjct: 732 -GNCTGGLSGYKCLCDAGW----VGINCEVDKNECL-SNPCQNGGTCDNLVNGYRCTCKK 785
Query: 528 G 530
G
Sbjct: 786 G 786
Score = 71.7 bits (168), Expect = 2e-12
Identities = 47/177 (26%), Positives = 75/177 (42%), Gaps = 3/177 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
VNT G+F C C GY R +EC P D C + G + CLC G++ G
Sbjct: 434 VNTDGAFHCECLKGY-AGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFK----G 488
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
+C +++EC+ + C + ++C C G+ G C +DI++C C +
Sbjct: 489 VHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGF--TGPVCQIDIDDC-SSTPCLNGA 545
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQAPCRNYAGGYRCDCPVG 530
+C++ + C C G+ G C + D C C++ Y C C G
Sbjct: 546 KCIDHPNGYECQCATGF----TGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPG 598
Score = 71.3 bits (167), Expect = 2e-12
Identities = 54/188 (28%), Positives = 80/188 (42%), Gaps = 13/188 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYE---L 176
V+ +G++RC C GY G+ + R P ++ C CLC +G+
Sbjct: 1041 VDGLGTYRCSCPLGY--TGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYC 1098
Query: 177 DEDGANCRDVDECERDT---HTCQQ--ICSNTEGSYECSCEDGYEKRGDACVD-INECHE 338
D +C D+ R H CQ +C N ++ C C GY G C + ++EC
Sbjct: 1099 DVPNVSC-DIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYT--GSYCEEQLDEC-A 1154
Query: 339 EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGY 509
C C + +G +RC C GY +G C + DEC Q CQ C + +
Sbjct: 1155 SNPCQHGATCSDFIGGYRCECVPGY----QGVNCEYEVDEC-QNQPCQNGGTCIDLVNHF 1209
Query: 510 RCDCPVGT 533
+C CP GT
Sbjct: 1210 KCSCPPGT 1217
Score = 70.5 bits (165), Expect = 4e-12
Identities = 54/184 (29%), Positives = 82/184 (44%), Gaps = 10/184 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRD-ECAVRPPPCDQLCHNT-DGSYDCLCRTGYELDE 182
+N GS++C C G+ G+ CA P C T D +++C C G+E
Sbjct: 199 LNLPGSYQCQCPQGF--TGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFE--- 253
Query: 183 DGANC-RDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACV-DINECH-EEGV 347
G+ C R++D+C H CQ +C + +Y C C + G C D++EC +
Sbjct: 254 -GSTCERNIDDCPN--HRCQNGGVCVDGVNTYNCRCPPQWT--GQFCTEDVDECLLQPNA 308
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ--APCRNYAGGYRCD 518
C + G C N G + CVC G+ G C + D+CA C + C + + C
Sbjct: 309 CQNGGTCANRNGGYGCVCVNGW----SGDDCSENIDDCA-FASCTPGSTCIDRVASFSCM 363
Query: 519 CPVG 530
CP G
Sbjct: 364 CPEG 367
Score = 69.7 bits (163), Expect = 6e-12
Identities = 54/180 (30%), Positives = 75/180 (41%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N + +RC C G++ V DECA P C + Y C C Y G
Sbjct: 774 NLVNGYRCTCKKGFKGYNCQVN-IDECASNPCLNQGTCFDDISGYTCHCVLPY----TGK 828
Query: 192 NCRDV-DECERDTHTCQQICSNTEG--SYECSCEDGYEKRGDAC-VDINECHEEGVCPSP 359
NC+ V C + +C + SY C C G++ G C +DI+EC + C +
Sbjct: 829 NCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQ--GQRCTIDIDECISK-PCMNH 885
Query: 360 GRCVNLLGSFRCVCPRGYR-LDAEGARCVDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
G C N GS+ C CP G+ +D E D D+C CQ C + + C C G
Sbjct: 886 GLCHNTQGSYMCECPPGFSGMDCE----EDIDDCL-ANPCQNGGSCMDGVNTFSCLCLPG 940
Score = 69.7 bits (163), Expect = 6e-12
Identities = 51/177 (28%), Positives = 72/177 (40%), Gaps = 6/177 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+N + C C GY DECA P C + G Y C C GY+ G
Sbjct: 1127 INAGNTHYCQCPLGYT-GSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQ----G 1181
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCPSPG 362
NC +VDEC+ C + ++CSC G RG C + I++C C + G
Sbjct: 1182 VNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPG--TRGLLCEENIDDCARGPHCLNGG 1239
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCV-DRDECAQ---TGRCQAPCRNYAGGYRCDC 521
+C++ +G + C C G+ G RC D +EC + C Y C C
Sbjct: 1240 QCMDRIGGYSCRCLPGF----AGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVC 1292
Score = 56.0 bits (129), Expect = 8e-08
Identities = 33/103 (32%), Positives = 45/103 (43%), Gaps = 3/103 (2%)
Frame = +3
Query: 231 TCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRG 410
TC + +T YEC+C+ G+ G C + C C + C + F C C G
Sbjct: 120 TCHMLSRDT---YECTCQVGFT--GKECQWTDACLSHP-CANGSTCTTVANQFSCKCLTG 173
Query: 411 YRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
+ G +C D +EC G CQ C N G Y+C CP G
Sbjct: 174 FT----GQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQG 212
Score = 45.6 bits (103), Expect = 1e-04
Identities = 50/179 (27%), Positives = 69/179 (38%), Gaps = 8/179 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGR-DECAVRPPPCDQL--CHNTDGSYDCLCRTGYELD 179
++ IG + C C PG+ AG G +EC P + C Y C+CR+ +
Sbjct: 1242 MDRIGGYSCRCLPGF--AGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFT-- 1297
Query: 180 EDGANCRD-VDECER----DTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEG 344
G +C VD C + + TC + SN + C C G+ G C + C +
Sbjct: 1298 --GRHCETFVDVCPQMPCLNGGTCA-VASNMPDGFICRCPPGFS--GARCQ--SSCGQVK 1350
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
C +CV+ RC CP D E C C G C P R Y C C
Sbjct: 1351 -CRKGEQCVHTASGPRCFCPS--PRDCESG-CAS-SPCQHGGSCH-PQRQ-PPYYSCQC 1402
>AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein.
Length = 2471
Score = 100 bits (239), Expect = 4e-21
Identities = 60/177 (33%), Positives = 87/177 (49%), Gaps = 7/177 (3%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAV-RPPPCDQL--CHNTDGSYDCLCRTGYELDEDGA 191
G + C C GY+ A DECA+ PC+ C NTDG++ C C GY G
Sbjct: 397 GQYICTCPQGYKGADC-TEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYA----GP 451
Query: 192 NCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGR 365
C D++EC D C + G + C C G+ +G C ++INEC + C + G+
Sbjct: 452 RCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGF--KGVHCELEINEC-QSNPCVNNGQ 508
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ-APCRNYAGGYRCDCPVG 530
CV+ + F+C+CP G+ G C +D D+C+ T A C ++ GY C C G
Sbjct: 509 CVDKVNRFQCLCPPGF----TGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATG 561
Score = 91.1 bits (216), Expect = 2e-18
Identities = 55/173 (31%), Positives = 82/173 (47%), Gaps = 4/173 (2%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-R 200
S+ C+C PG++ R DEC +P LCHNT GSY C C G+ G +C
Sbjct: 856 SYTCLCAPGWQ-GQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGF----SGMDCEE 910
Query: 201 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNL 377
D+D+C + C + ++ C C G+ GD C D+NEC E C + G C +
Sbjct: 911 DIDDCLANPCQNGGSCMDGVNTFSCLCLPGF--TGDKCQTDMNECLSE-PCKNGGTCSDY 967
Query: 378 LGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ-APCRNYAGGYRCDCPVG 530
+ S+ C C G+ +G C + +EC ++ C + + C CPVG
Sbjct: 968 VNSYTCKCQAGF----DGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVG 1016
Score = 88.6 bits (210), Expect = 1e-17
Identities = 59/179 (32%), Positives = 90/179 (50%), Gaps = 6/179 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGV-RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
NT GS+ C C PG+ +G D+C P C + ++ CLC G+ G
Sbjct: 890 NTQGSYMCECPPGF--SGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGF----TG 943
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSPG 362
C+ D++EC + CS+ SY C C+ G++ G C +INEC E C + G
Sbjct: 944 DKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFD--GVHCENNINECTESS-CFNGG 1000
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCV-DRDECAQTGRC--QAPCRNYAGGYRCDCPVG 530
CV+ + SF C+CP G+ G+ C+ + +EC+ + C + C + G YRC CP+G
Sbjct: 1001 TCVDGINSFSCLCPVGF----TGSFCLHEINECS-SHPCLNEGTCVDGLGTYRCSCPLG 1054
Score = 81.8 bits (193), Expect = 1e-15
Identities = 54/176 (30%), Positives = 72/176 (40%), Gaps = 3/176 (1%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
I S+ C+C PGY A + DEC P D C + Y C C+ G G NC
Sbjct: 588 IDSYTCICNPGYMGAICSDQ-IDECYSSPCLNDGRCIDLVNGYQCNCQPG----TSGVNC 642
Query: 198 R-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCV 371
+ D+C + IC + Y C C G+ G C +DI+EC C C+
Sbjct: 643 EINFDDCASNP-CIHGICMDGINRYSCVCSPGFT--GQRCNIDIDEC-ASNPCRKGATCI 698
Query: 372 NLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQAPCRNYAGGYRCDCPVGTV 536
N + FRC+CP G C + +EC C GY+C C G V
Sbjct: 699 NGVNGFRCICPEG----PHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWV 750
Score = 80.6 bits (190), Expect = 3e-15
Identities = 52/177 (29%), Positives = 79/177 (44%), Gaps = 3/177 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
V+ + F+C+C PG+ + D+C+ P C + Y+C C TG+ G
Sbjct: 510 VDKVNRFQCLCPPGFTGPVCQI-DIDDCSSTPCLNGAKCIDHPNGYECQCATGFT----G 564
Query: 189 ANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCPSPG 362
C + +D C+ D Q C + SY C C GY G C D I+EC+ C + G
Sbjct: 565 VLCEENIDNCDPDPCHHGQ-CQDGIDSYTCICNPGY--MGAICSDQIDECYSSP-CLNDG 620
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
RC++L+ ++C C G G C ++ D+CA C + Y C C G
Sbjct: 621 RCIDLVNGYQCNCQPG----TSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPG 673
Score = 77.8 bits (183), Expect = 2e-14
Identities = 56/180 (31%), Positives = 76/180 (42%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N G + CVC G+ D+CA C + S+ C+C G + G
Sbjct: 317 NRNGGYGCVCVNGWSGDDCS-ENIDDCAFASCTPGSTCIDRVASFSCMCPEG----KAGL 371
Query: 192 NCRDVDECERDTHTCQQICSNT--EGSYECSCEDGYEKRGDACVDINECH--EEGVCPSP 359
C D C + +C G Y C+C GY K D D++EC C
Sbjct: 372 LCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGY-KGADCTEDVDECAMANSNPCEHA 430
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
G+CVN G+F C C +GY G RC +D +EC + CQ A C + GG+ C C G
Sbjct: 431 GKCVNTDGAFHCECLKGY----AGPRCEMDINEC-HSDPCQNDATCLDKIGGFTCLCMPG 485
Score = 77.4 bits (182), Expect = 3e-14
Identities = 57/185 (30%), Positives = 82/185 (44%), Gaps = 12/185 (6%)
Frame = +3
Query: 6 GVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
GVNT F C+C PG+ + +EC P C + SY C C+ G+ D
Sbjct: 929 GVNT---FSCLCLPGFT-GDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGF----D 980
Query: 186 GANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSP 359
G +C + ++EC + C + S+ C C G+ G C+ +INEC C +
Sbjct: 981 GVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFT--GSFCLHEINECSSHP-CLNE 1037
Query: 360 GRCVNLLGSFRCVCPRGY--RLDAEGARCVDRDECAQTGRC-----QAPC---RNYAGGY 509
G CV+ LG++RC CP GY + R C G C ++ C +AG Y
Sbjct: 1038 GTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAY 1097
Query: 510 RCDCP 524
CD P
Sbjct: 1098 -CDVP 1101
Score = 77.4 bits (182), Expect = 3e-14
Identities = 46/142 (32%), Positives = 68/142 (47%), Gaps = 5/142 (3%)
Frame = +3
Query: 120 LCHNTDGSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYE 296
+C N ++ C C GY G+ C + +DEC + CS+ G Y C C GY+
Sbjct: 1125 VCINAGNTHYCQCPLGYT----GSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQ 1180
Query: 297 KRGDAC-VDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTG 470
G C +++EC + C + G C++L+ F+C CP G R G C + D+CA+
Sbjct: 1181 --GVNCEYEVDECQNQP-CQNGGTCIDLVNHFKCSCPPGTR----GLLCEENIDDCARGP 1233
Query: 471 RC--QAPCRNYAGGYRCDCPVG 530
C C + GGY C C G
Sbjct: 1234 HCLNGGQCMDRIGGYSCRCLPG 1255
Score = 75.8 bits (178), Expect = 1e-13
Identities = 57/186 (30%), Positives = 82/186 (44%), Gaps = 12/186 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
V+ I SF C+C G+ + +EC+ P + C + G+Y C C GY G
Sbjct: 1003 VDGINSFSCLCPVGFT-GSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYT----G 1057
Query: 189 ANCRD-VDECERDTHTCQQICSNTEGSYECSCEDG----YEKRGDACVDINECHE----E 341
NC+ V+ C R + C + +C C G Y + DI E
Sbjct: 1058 KNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVE 1117
Query: 342 GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ--APCRNYAGGYR 512
+C G C+N + C CP GY G+ C ++ DECA + CQ A C ++ GGYR
Sbjct: 1118 HLCQHSGVCINAGNTHYCQCPLGY----TGSYCEEQLDECA-SNPCQHGATCSDFIGGYR 1172
Query: 513 CDCPVG 530
C+C G
Sbjct: 1173 CECVPG 1178
Score = 74.5 bits (175), Expect = 2e-13
Identities = 55/173 (31%), Positives = 75/173 (43%), Gaps = 5/173 (2%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRD 203
+ C C G+ D C P PC C + SY C+C GY GA C D
Sbjct: 554 YECQCATGFTGV-LCEENIDNCD--PDPCHHGQCQDGIDSYTCICNPGYM----GAICSD 606
Query: 204 -VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNL 377
+DEC C + Y+C+C+ G G C ++ ++C C G C++
Sbjct: 607 QIDECYSSPCLNDGRCIDLVNGYQCNCQPGTS--GVNCEINFDDC-ASNPCIH-GICMDG 662
Query: 378 LGSFRCVCPRGYRLDAEGARC-VDRDECAQTG-RCQAPCRNYAGGYRCDCPVG 530
+ + CVC G+ G RC +D DECA R A C N G+RC CP G
Sbjct: 663 INRYSCVCSPGFT----GQRCNIDIDECASNPCRKGATCINGVNGFRCICPEG 711
Score = 74.1 bits (174), Expect = 3e-13
Identities = 53/180 (29%), Positives = 82/180 (45%), Gaps = 5/180 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ IG F C+C PG++ + +EC P + C + + CLC G+ G
Sbjct: 472 LDKIGGFTCLCMPGFKGVHCELE-INECQSNPCVNNGQCVDKVNRFQCLCPPGF----TG 526
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCPSPG 362
C+ D+D+C C + YEC C G+ G C + I+ C + C G
Sbjct: 527 PVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGF--TGVLCEENIDNC-DPDPC-HHG 582
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRC--QAPCRNYAGGYRCDCPVGT 533
+C + + S+ C+C GY GA C D+ DEC + C C + GY+C+C GT
Sbjct: 583 QCQDGIDSYTCICNPGYM----GAICSDQIDEC-YSSPCLNDGRCIDLVNGYQCNCQPGT 637
Score = 74.1 bits (174), Expect = 3e-13
Identities = 55/173 (31%), Positives = 76/173 (43%), Gaps = 5/173 (2%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
I + CVC PG+ + DECA P C N + C+C G +C
Sbjct: 663 INRYSCVCSPGFTGQRCNI-DIDECASNPCRKGATCINGVNGFRCICPEG----PHHPSC 717
Query: 198 -RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCV 371
V+EC + C+ Y+C C+ G+ G C VD NEC C + G C
Sbjct: 718 YSQVNECLSNP-CIHGNCTGGLSGYKCLCDAGWV--GINCEVDKNECLSNP-CQNGGTCD 773
Query: 372 NLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRC--QAPCRNYAGGYRCDC 521
NL+ +RC C +G++ G C V+ DECA + C Q C + GY C C
Sbjct: 774 NLVNGYRCTCKKGFK----GYNCQVNIDECA-SNPCLNQGTCFDDISGYTCHC 821
Score = 73.7 bits (173), Expect = 4e-13
Identities = 51/181 (28%), Positives = 75/181 (41%), Gaps = 5/181 (2%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
R ++ + ++C C PG + D+CA P +C + Y C+C G+
Sbjct: 621 RCIDLVNGYQCNCQPGTSGVNCEINF-DDCASNPC-IHGICMDGINRYSCVCSPGFT--- 675
Query: 183 DGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCPS 356
G C D+DEC + C N + C C +G +C +NEC
Sbjct: 676 -GQRCNIDIDECASNPCRKGATCINGVNGFRCICPEG--PHHPSCYSQVNECLSNPCIH- 731
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPV 527
G C L ++C+C G+ G C VD++EC + CQ C N GYRC C
Sbjct: 732 -GNCTGGLSGYKCLCDAGW----VGINCEVDKNECL-SNPCQNGGTCDNLVNGYRCTCKK 785
Query: 528 G 530
G
Sbjct: 786 G 786
Score = 71.7 bits (168), Expect = 2e-12
Identities = 47/177 (26%), Positives = 75/177 (42%), Gaps = 3/177 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
VNT G+F C C GY R +EC P D C + G + CLC G++ G
Sbjct: 434 VNTDGAFHCECLKGY-AGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFK----G 488
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
+C +++EC+ + C + ++C C G+ G C +DI++C C +
Sbjct: 489 VHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGF--TGPVCQIDIDDC-SSTPCLNGA 545
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQAPCRNYAGGYRCDCPVG 530
+C++ + C C G+ G C + D C C++ Y C C G
Sbjct: 546 KCIDHPNGYECQCATGF----TGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPG 598
Score = 71.3 bits (167), Expect = 2e-12
Identities = 54/188 (28%), Positives = 80/188 (42%), Gaps = 13/188 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYE---L 176
V+ +G++RC C GY G+ + R P ++ C CLC +G+
Sbjct: 1041 VDGLGTYRCSCPLGY--TGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYC 1098
Query: 177 DEDGANCRDVDECERDT---HTCQQ--ICSNTEGSYECSCEDGYEKRGDACVD-INECHE 338
D +C D+ R H CQ +C N ++ C C GY G C + ++EC
Sbjct: 1099 DVPNVSC-DIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYT--GSYCEEQLDEC-A 1154
Query: 339 EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGY 509
C C + +G +RC C GY +G C + DEC Q CQ C + +
Sbjct: 1155 SNPCQHGATCSDFIGGYRCECVPGY----QGVNCEYEVDEC-QNQPCQNGGTCIDLVNHF 1209
Query: 510 RCDCPVGT 533
+C CP GT
Sbjct: 1210 KCSCPPGT 1217
Score = 70.5 bits (165), Expect = 4e-12
Identities = 54/189 (28%), Positives = 74/189 (39%), Gaps = 20/189 (10%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAV-RPPPCDQLCHNTD-GSYDCLCRTGYELDEDGA 191
+G C C G+ C V RP CH +Y+C C+ G+ G
Sbjct: 85 LGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFT----GK 140
Query: 192 NCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
C+ D C +H C C+ + C C G+ G C D+NEC G C G
Sbjct: 141 ECQWTDACL--SHPCANGSTCTTVANQFSCKCLTGFT--GQKCETDVNECDIPGHCQHGG 196
Query: 363 RCVNLLGSFRCVCPRGYR--------LDAEGARCVDRDECAQTGRCQAPCRNYAG--GYR 512
C+NL GS++C C +G+ + + CV+ C QTG C G G
Sbjct: 197 TCLNLPGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGST 256
Query: 513 C-----DCP 524
C DCP
Sbjct: 257 CERNIDDCP 265
Score = 69.7 bits (163), Expect = 6e-12
Identities = 54/184 (29%), Positives = 82/184 (44%), Gaps = 10/184 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRD-ECAVRPPPCDQLCHNT-DGSYDCLCRTGYELDE 182
+N GS++C C G+ G+ CA P C T D +++C C G+E
Sbjct: 199 LNLPGSYQCQCLQGF--TGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFE--- 253
Query: 183 DGANC-RDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACV-DINECH-EEGV 347
G+ C R++D+C H CQ +C + +Y C C + G C D++EC +
Sbjct: 254 -GSTCERNIDDCPN--HRCQNGGVCVDGVNTYNCRCPPQWT--GQFCTEDVDECLLQPNA 308
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ--APCRNYAGGYRCD 518
C + G C N G + CVC G+ G C + D+CA C + C + + C
Sbjct: 309 CQNGGTCANRNGGYGCVCVNGW----SGDDCSENIDDCA-FASCTPGSTCIDRVASFSCM 363
Query: 519 CPVG 530
CP G
Sbjct: 364 CPEG 367
Score = 69.7 bits (163), Expect = 6e-12
Identities = 54/180 (30%), Positives = 75/180 (41%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N + +RC C G++ V DECA P C + Y C C Y G
Sbjct: 774 NLVNGYRCTCKKGFKGYNCQVN-IDECASNPCLNQGTCFDDISGYTCHCVLPY----TGK 828
Query: 192 NCRDV-DECERDTHTCQQICSNTEG--SYECSCEDGYEKRGDAC-VDINECHEEGVCPSP 359
NC+ V C + +C + SY C C G++ G C +DI+EC + C +
Sbjct: 829 NCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQ--GQRCTIDIDECISK-PCMNH 885
Query: 360 GRCVNLLGSFRCVCPRGYR-LDAEGARCVDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
G C N GS+ C CP G+ +D E D D+C CQ C + + C C G
Sbjct: 886 GLCHNTQGSYMCECPPGFSGMDCE----EDIDDCL-ANPCQNGGSCMDGVNTFSCLCLPG 940
Score = 69.7 bits (163), Expect = 6e-12
Identities = 51/177 (28%), Positives = 72/177 (40%), Gaps = 6/177 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+N + C C GY DECA P C + G Y C C GY+ G
Sbjct: 1127 INAGNTHYCQCPLGYT-GSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQ----G 1181
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCPSPG 362
NC +VDEC+ C + ++CSC G RG C + I++C C + G
Sbjct: 1182 VNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPG--TRGLLCEENIDDCARGPHCLNGG 1239
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCV-DRDECAQ---TGRCQAPCRNYAGGYRCDC 521
+C++ +G + C C G+ G RC D +EC + C Y C C
Sbjct: 1240 QCMDRIGGYSCRCLPGF----AGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVC 1292
Score = 52.0 bits (119), Expect = 1e-06
Identities = 32/103 (31%), Positives = 44/103 (42%), Gaps = 3/103 (2%)
Frame = +3
Query: 231 TCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRG 410
TC + +T YEC+C+ G+ G C + C C + C + F C C G
Sbjct: 120 TCHMLSRDT---YECTCQVGFT--GKECQWTDACLSHP-CANGSTCTTVANQFSCKCLTG 173
Query: 411 YRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
+ G +C D +EC G CQ C N G Y+C C G
Sbjct: 174 FT----GQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQG 212
Score = 45.6 bits (103), Expect = 1e-04
Identities = 50/179 (27%), Positives = 69/179 (38%), Gaps = 8/179 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGR-DECAVRPPPCDQL--CHNTDGSYDCLCRTGYELD 179
++ IG + C C PG+ AG G +EC P + C Y C+CR+ +
Sbjct: 1242 MDRIGGYSCRCLPGF--AGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFT-- 1297
Query: 180 EDGANCRD-VDECER----DTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEG 344
G +C VD C + + TC + SN + C C G+ G C + C +
Sbjct: 1298 --GRHCETFVDVCPQMPCLNGGTCA-VASNMPDGFICRCPPGFS--GARCQ--SSCGQVK 1350
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
C +CV+ RC CP D E C C G C P R Y C C
Sbjct: 1351 -CRKGEQCVHTASGPRCFCPS--PRDCESG-CAS-SPCQHGGSCH-PQRQ-PPYYSCQC 1402
>AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein.
Length = 2471
Score = 100 bits (239), Expect = 4e-21
Identities = 60/177 (33%), Positives = 87/177 (49%), Gaps = 7/177 (3%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAV-RPPPCDQL--CHNTDGSYDCLCRTGYELDEDGA 191
G + C C GY+ A DECA+ PC+ C NTDG++ C C GY G
Sbjct: 397 GQYICTCPQGYKGADC-TEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYA----GP 451
Query: 192 NCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGR 365
C D++EC D C + G + C C G+ +G C ++INEC + C + G+
Sbjct: 452 RCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGF--KGVHCELEINEC-QSNPCVNNGQ 508
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ-APCRNYAGGYRCDCPVG 530
CV+ + F+C+CP G+ G C +D D+C+ T A C ++ GY C C G
Sbjct: 509 CVDKVNRFQCLCPPGF----TGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATG 561
Score = 91.1 bits (216), Expect = 2e-18
Identities = 55/173 (31%), Positives = 82/173 (47%), Gaps = 4/173 (2%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-R 200
S+ C+C PG++ R DEC +P LCHNT GSY C C G+ G +C
Sbjct: 856 SYTCLCAPGWQ-GQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGF----SGMDCEE 910
Query: 201 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNL 377
D+D+C + C + ++ C C G+ GD C D+NEC E C + G C +
Sbjct: 911 DIDDCLANPCQNGGSCMDGVNTFSCLCLPGF--TGDKCQTDMNECLSE-PCKNGGTCSDY 967
Query: 378 LGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ-APCRNYAGGYRCDCPVG 530
+ S+ C C G+ +G C + +EC ++ C + + C CPVG
Sbjct: 968 VNSYTCKCQAGF----DGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVG 1016
Score = 88.6 bits (210), Expect = 1e-17
Identities = 59/179 (32%), Positives = 90/179 (50%), Gaps = 6/179 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGV-RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
NT GS+ C C PG+ +G D+C P C + ++ CLC G+ G
Sbjct: 890 NTQGSYMCECPPGF--SGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGF----TG 943
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSPG 362
C+ D++EC + CS+ SY C C+ G++ G C +INEC E C + G
Sbjct: 944 DKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFD--GVHCENNINECTESS-CFNGG 1000
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCV-DRDECAQTGRC--QAPCRNYAGGYRCDCPVG 530
CV+ + SF C+CP G+ G+ C+ + +EC+ + C + C + G YRC CP+G
Sbjct: 1001 TCVDGINSFSCLCPVGF----TGSFCLHEINECS-SHPCLNEGTCVDGLGTYRCSCPLG 1054
Score = 81.8 bits (193), Expect = 1e-15
Identities = 54/176 (30%), Positives = 72/176 (40%), Gaps = 3/176 (1%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
I S+ C+C PGY A + DEC P D C + Y C C+ G G NC
Sbjct: 588 IDSYTCICNPGYMGAICSDQ-IDECYSSPCLNDGRCIDLVNGYQCNCQPG----TSGVNC 642
Query: 198 R-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCV 371
+ D+C + IC + Y C C G+ G C +DI+EC C C+
Sbjct: 643 EINFDDCASNP-CIHGICMDGINRYSCVCSPGFT--GQRCNIDIDEC-ASNPCRKGATCI 698
Query: 372 NLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQAPCRNYAGGYRCDCPVGTV 536
N + FRC+CP G C + +EC C GY+C C G V
Sbjct: 699 NGVNGFRCICPEG----PHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWV 750
Score = 80.6 bits (190), Expect = 3e-15
Identities = 52/177 (29%), Positives = 79/177 (44%), Gaps = 3/177 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
V+ + F+C+C PG+ + D+C+ P C + Y+C C TG+ G
Sbjct: 510 VDKVNRFQCLCPPGFTGPVCQI-DIDDCSSTPCLNGAKCIDHPNGYECQCATGFT----G 564
Query: 189 ANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCPSPG 362
C + +D C+ D Q C + SY C C GY G C D I+EC+ C + G
Sbjct: 565 VLCEENIDNCDPDPCHHGQ-CQDGIDSYTCICNPGY--MGAICSDQIDECYSSP-CLNDG 620
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
RC++L+ ++C C G G C ++ D+CA C + Y C C G
Sbjct: 621 RCIDLVNGYQCNCQPG----TSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPG 673
Score = 77.8 bits (183), Expect = 2e-14
Identities = 56/180 (31%), Positives = 76/180 (42%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N G + CVC G+ D+CA C + S+ C+C G + G
Sbjct: 317 NRNGGYGCVCVNGWSGDDCS-ENIDDCAFASCTPGSTCIDRVASFSCMCPEG----KAGL 371
Query: 192 NCRDVDECERDTHTCQQICSNT--EGSYECSCEDGYEKRGDACVDINECH--EEGVCPSP 359
C D C + +C G Y C+C GY K D D++EC C
Sbjct: 372 LCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGY-KGADCTEDVDECAMANSNPCEHA 430
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
G+CVN G+F C C +GY G RC +D +EC + CQ A C + GG+ C C G
Sbjct: 431 GKCVNTDGAFHCECLKGY----AGPRCEMDINEC-HSDPCQNDATCLDKIGGFTCLCMPG 485
Score = 77.4 bits (182), Expect = 3e-14
Identities = 57/185 (30%), Positives = 82/185 (44%), Gaps = 12/185 (6%)
Frame = +3
Query: 6 GVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
GVNT F C+C PG+ + +EC P C + SY C C+ G+ D
Sbjct: 929 GVNT---FSCLCLPGFT-GDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGF----D 980
Query: 186 GANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSP 359
G +C + ++EC + C + S+ C C G+ G C+ +INEC C +
Sbjct: 981 GVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFT--GSFCLHEINECSSHP-CLNE 1037
Query: 360 GRCVNLLGSFRCVCPRGY--RLDAEGARCVDRDECAQTGRC-----QAPC---RNYAGGY 509
G CV+ LG++RC CP GY + R C G C ++ C +AG Y
Sbjct: 1038 GTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAY 1097
Query: 510 RCDCP 524
CD P
Sbjct: 1098 -CDVP 1101
Score = 77.4 bits (182), Expect = 3e-14
Identities = 46/142 (32%), Positives = 68/142 (47%), Gaps = 5/142 (3%)
Frame = +3
Query: 120 LCHNTDGSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYE 296
+C N ++ C C GY G+ C + +DEC + CS+ G Y C C GY+
Sbjct: 1125 VCINAGNTHYCQCPLGYT----GSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQ 1180
Query: 297 KRGDAC-VDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTG 470
G C +++EC + C + G C++L+ F+C CP G R G C + D+CA+
Sbjct: 1181 --GVNCEYEVDECQNQP-CQNGGTCIDLVNHFKCSCPPGTR----GLLCEENIDDCARGP 1233
Query: 471 RC--QAPCRNYAGGYRCDCPVG 530
C C + GGY C C G
Sbjct: 1234 HCLNGGQCMDRIGGYSCRCLPG 1255
Score = 75.8 bits (178), Expect = 1e-13
Identities = 57/186 (30%), Positives = 82/186 (44%), Gaps = 12/186 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
V+ I SF C+C G+ + +EC+ P + C + G+Y C C GY G
Sbjct: 1003 VDGINSFSCLCPVGFT-GSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYT----G 1057
Query: 189 ANCRD-VDECERDTHTCQQICSNTEGSYECSCEDG----YEKRGDACVDINECHE----E 341
NC+ V+ C R + C + +C C G Y + DI E
Sbjct: 1058 KNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVE 1117
Query: 342 GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ--APCRNYAGGYR 512
+C G C+N + C CP GY G+ C ++ DECA + CQ A C ++ GGYR
Sbjct: 1118 HLCQHSGVCINAGNTHYCQCPLGY----TGSYCEEQLDECA-SNPCQHGATCSDFIGGYR 1172
Query: 513 CDCPVG 530
C+C G
Sbjct: 1173 CECVPG 1178
Score = 74.5 bits (175), Expect = 2e-13
Identities = 55/189 (29%), Positives = 75/189 (39%), Gaps = 20/189 (10%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAV-RPPPCDQLCHNTD-GSYDCLCRTGYELDEDGA 191
+G C C G+ C V RP CH +Y+C C+ G+ G
Sbjct: 85 LGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFT----GK 140
Query: 192 NCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
C+ D C +H C C+ + C C G+ G C D+NEC G C G
Sbjct: 141 ECQWTDACL--SHPCANGSTCTTVANQFSCKCLTGFT--GQKCETDVNECDIPGHCQHGG 196
Query: 363 RCVNLLGSFRCVCPRGYR--------LDAEGARCVDRDECAQTGRCQAPCRNYAG--GYR 512
C+NL GS++C CP+G+ + + CV+ C QTG C G G
Sbjct: 197 TCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGST 256
Query: 513 C-----DCP 524
C DCP
Sbjct: 257 CERNIDDCP 265
Score = 74.5 bits (175), Expect = 2e-13
Identities = 55/173 (31%), Positives = 75/173 (43%), Gaps = 5/173 (2%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRD 203
+ C C G+ D C P PC C + SY C+C GY GA C D
Sbjct: 554 YECQCATGFTGV-LCEENIDNCD--PDPCHHGQCQDGIDSYTCICNPGYM----GAICSD 606
Query: 204 -VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNL 377
+DEC C + Y+C+C+ G G C ++ ++C C G C++
Sbjct: 607 QIDECYSSPCLNDGRCIDLVNGYQCNCQPGTS--GVNCEINFDDC-ASNPCIH-GICMDG 662
Query: 378 LGSFRCVCPRGYRLDAEGARC-VDRDECAQTG-RCQAPCRNYAGGYRCDCPVG 530
+ + CVC G+ G RC +D DECA R A C N G+RC CP G
Sbjct: 663 INRYSCVCSPGFT----GQRCNIDIDECASNPCRKGATCINGVNGFRCICPEG 711
Score = 74.1 bits (174), Expect = 3e-13
Identities = 53/180 (29%), Positives = 82/180 (45%), Gaps = 5/180 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ IG F C+C PG++ + +EC P + C + + CLC G+ G
Sbjct: 472 LDKIGGFTCLCMPGFKGVHCELE-INECQSNPCVNNGQCVDKVNRFQCLCPPGF----TG 526
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCPSPG 362
C+ D+D+C C + YEC C G+ G C + I+ C + C G
Sbjct: 527 PVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGF--TGVLCEENIDNC-DPDPC-HHG 582
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRC--QAPCRNYAGGYRCDCPVGT 533
+C + + S+ C+C GY GA C D+ DEC + C C + GY+C+C GT
Sbjct: 583 QCQDGIDSYTCICNPGYM----GAICSDQIDEC-YSSPCLNDGRCIDLVNGYQCNCQPGT 637
Score = 74.1 bits (174), Expect = 3e-13
Identities = 55/173 (31%), Positives = 76/173 (43%), Gaps = 5/173 (2%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
I + CVC PG+ + DECA P C N + C+C G +C
Sbjct: 663 INRYSCVCSPGFTGQRCNI-DIDECASNPCRKGATCINGVNGFRCICPEG----PHHPSC 717
Query: 198 -RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCV 371
V+EC + C+ Y+C C+ G+ G C VD NEC C + G C
Sbjct: 718 YSQVNECLSNP-CIHGNCTGGLSGYKCLCDAGWV--GINCEVDKNECLSNP-CQNGGTCD 773
Query: 372 NLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRC--QAPCRNYAGGYRCDC 521
NL+ +RC C +G++ G C V+ DECA + C Q C + GY C C
Sbjct: 774 NLVNGYRCTCKKGFK----GYNCQVNIDECA-SNPCLNQGTCFDDISGYTCHC 821
Score = 73.7 bits (173), Expect = 4e-13
Identities = 51/181 (28%), Positives = 75/181 (41%), Gaps = 5/181 (2%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
R ++ + ++C C PG + D+CA P +C + Y C+C G+
Sbjct: 621 RCIDLVNGYQCNCQPGTSGVNCEINF-DDCASNPC-IHGICMDGINRYSCVCSPGFT--- 675
Query: 183 DGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCPS 356
G C D+DEC + C N + C C +G +C +NEC
Sbjct: 676 -GQRCNIDIDECASNPCRKGATCINGVNGFRCICPEG--PHHPSCYSQVNECLSNPCIH- 731
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPV 527
G C L ++C+C G+ G C VD++EC + CQ C N GYRC C
Sbjct: 732 -GNCTGGLSGYKCLCDAGW----VGINCEVDKNECL-SNPCQNGGTCDNLVNGYRCTCKK 785
Query: 528 G 530
G
Sbjct: 786 G 786
Score = 71.7 bits (168), Expect = 2e-12
Identities = 47/177 (26%), Positives = 75/177 (42%), Gaps = 3/177 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
VNT G+F C C GY R +EC P D C + G + CLC G++ G
Sbjct: 434 VNTDGAFHCECLKGY-AGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFK----G 488
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
+C +++EC+ + C + ++C C G+ G C +DI++C C +
Sbjct: 489 VHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGF--TGPVCQIDIDDC-SSTPCLNGA 545
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQAPCRNYAGGYRCDCPVG 530
+C++ + C C G+ G C + D C C++ Y C C G
Sbjct: 546 KCIDHPNGYECQCATGF----TGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPG 598
Score = 71.3 bits (167), Expect = 2e-12
Identities = 54/188 (28%), Positives = 80/188 (42%), Gaps = 13/188 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYE---L 176
V+ +G++RC C GY G+ + R P ++ C CLC +G+
Sbjct: 1041 VDGLGTYRCSCPLGY--TGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYC 1098
Query: 177 DEDGANCRDVDECERDT---HTCQQ--ICSNTEGSYECSCEDGYEKRGDACVD-INECHE 338
D +C D+ R H CQ +C N ++ C C GY G C + ++EC
Sbjct: 1099 DVPNVSC-DIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYT--GSYCEEQLDEC-A 1154
Query: 339 EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGY 509
C C + +G +RC C GY +G C + DEC Q CQ C + +
Sbjct: 1155 SNPCQHGATCSDFIGGYRCECVPGY----QGVNCEYEVDEC-QNQPCQNGGTCIDLVNHF 1209
Query: 510 RCDCPVGT 533
+C CP GT
Sbjct: 1210 KCSCPPGT 1217
Score = 70.5 bits (165), Expect = 4e-12
Identities = 54/184 (29%), Positives = 82/184 (44%), Gaps = 10/184 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRD-ECAVRPPPCDQLCHNT-DGSYDCLCRTGYELDE 182
+N GS++C C G+ G+ CA P C T D +++C C G+E
Sbjct: 199 LNLPGSYQCQCPQGF--TGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFE--- 253
Query: 183 DGANC-RDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACV-DINECH-EEGV 347
G+ C R++D+C H CQ +C + +Y C C + G C D++EC +
Sbjct: 254 -GSTCERNIDDCPN--HRCQNGGVCVDGVNTYNCRCPPQWT--GQFCTEDVDECLLQPNA 308
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ--APCRNYAGGYRCD 518
C + G C N G + CVC G+ G C + D+CA C + C + + C
Sbjct: 309 CQNGGTCANRNGGYGCVCVNGW----SGDDCSENIDDCA-FASCTPGSTCIDRVASFSCM 363
Query: 519 CPVG 530
CP G
Sbjct: 364 CPEG 367
Score = 69.7 bits (163), Expect = 6e-12
Identities = 54/180 (30%), Positives = 75/180 (41%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N + +RC C G++ V DECA P C + Y C C Y G
Sbjct: 774 NLVNGYRCTCKKGFKGYNCQVN-IDECASNPCLNQGTCFDDISGYTCHCVLPY----TGK 828
Query: 192 NCRDV-DECERDTHTCQQICSNTEG--SYECSCEDGYEKRGDAC-VDINECHEEGVCPSP 359
NC+ V C + +C + SY C C G++ G C +DI+EC + C +
Sbjct: 829 NCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQ--GQRCTIDIDECISK-PCMNH 885
Query: 360 GRCVNLLGSFRCVCPRGYR-LDAEGARCVDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
G C N GS+ C CP G+ +D E D D+C CQ C + + C C G
Sbjct: 886 GLCHNTQGSYMCECPPGFSGMDCE----EDIDDCL-ANPCQNGGSCMDGVNTFSCLCLPG 940
Score = 69.7 bits (163), Expect = 6e-12
Identities = 51/177 (28%), Positives = 72/177 (40%), Gaps = 6/177 (3%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+N + C C GY DECA P C + G Y C C GY+ G
Sbjct: 1127 INAGNTHYCQCPLGYT-GSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQ----G 1181
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCPSPG 362
NC +VDEC+ C + ++CSC G RG C + I++C C + G
Sbjct: 1182 VNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPG--TRGLLCEENIDDCARGPHCLNGG 1239
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCV-DRDECAQ---TGRCQAPCRNYAGGYRCDC 521
+C++ +G + C C G+ G RC D +EC + C Y C C
Sbjct: 1240 QCMDRIGGYSCRCLPGF----AGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVC 1292
Score = 56.0 bits (129), Expect = 8e-08
Identities = 33/103 (32%), Positives = 45/103 (43%), Gaps = 3/103 (2%)
Frame = +3
Query: 231 TCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRG 410
TC + +T YEC+C+ G+ G C + C C + C + F C C G
Sbjct: 120 TCHMLSRDT---YECTCQVGFT--GKECQWTDACLSHP-CANGSTCTTVANQFSCKCLTG 173
Query: 411 YRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
+ G +C D +EC G CQ C N G Y+C CP G
Sbjct: 174 FT----GQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQG 212
Score = 45.6 bits (103), Expect = 1e-04
Identities = 50/179 (27%), Positives = 69/179 (38%), Gaps = 8/179 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGR-DECAVRPPPCDQL--CHNTDGSYDCLCRTGYELD 179
++ IG + C C PG+ AG G +EC P + C Y C+CR+ +
Sbjct: 1242 MDRIGGYSCRCLPGF--AGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFT-- 1297
Query: 180 EDGANCRD-VDECER----DTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEG 344
G +C VD C + + TC + SN + C C G+ G C + C +
Sbjct: 1298 --GRHCETFVDVCPQMPCLNGGTCA-VASNMPDGFICRCPPGFS--GARCQ--SSCGQVK 1350
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
C +CV+ RC CP D E C C G C P R Y C C
Sbjct: 1351 -CRKGEQCVHTASGPRCFCPS--PRDCESG-CAS-SPCQHGGSCH-PQRQ-PPYYSCQC 1402
>AL117551-1|CAB55988.1| 511|Homo sapiens hypothetical protein
protein.
Length = 511
Score = 99.1 bits (236), Expect = 9e-21
Identities = 50/144 (34%), Positives = 70/144 (48%), Gaps = 3/144 (2%)
Frame = +3
Query: 111 CDQ-LCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCED 287
CD +C NT GS+ C C +GY L D ++C D+DEC+ C NT GSY C C
Sbjct: 3 CDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQ 62
Query: 288 GYE-KRGDACVDINECHEE-GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECA 461
G+ G C DI+EC ++ +C G C NL GS+ CVC G+ + C + ++
Sbjct: 63 GHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPH 122
Query: 462 QTGRCQAPCRNYAGGYRCDCPVGT 533
C N+ CD + T
Sbjct: 123 HKKECYL---NFDDTVFCDSVLAT 143
Score = 84.6 bits (200), Expect = 2e-16
Identities = 39/100 (39%), Positives = 53/100 (53%), Gaps = 7/100 (7%)
Frame = +3
Query: 123 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCED--GYE 296
C NT Y+C C+ G+ D + C DVDEC +++ +C NT G Y C+C Y
Sbjct: 218 CVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYS 277
Query: 297 KRGDAC-----VDINECHEEGVCPSPGRCVNLLGSFRCVC 401
C +D++EC + C PGRCVNL GS+RC C
Sbjct: 278 PAQRQCLSPEEMDVDECQDPAAC-RPGRCVNLPGSYRCEC 316
Score = 83.0 bits (196), Expect = 6e-16
Identities = 62/190 (32%), Positives = 83/190 (43%), Gaps = 17/190 (8%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTG--YELDEDGANC--- 197
C C G AG G D C + P P + + LC G Y D + N
Sbjct: 150 CCCSLG---AGWG----DHCEIYPCPV-----YSSAEFHSLCPDGKGYTQDNNIVNYGIP 197
Query: 198 --RDVDECER-DTHTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCPSP 359
RD+DEC + C++ C NT+ YEC C+ G+ G+ CVD++EC +E C +
Sbjct: 198 AHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRN- 256
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARC-----VDRDECAQTGRCQ-APCRNYAGGYRCDC 521
G C N G +RC C +C +D DEC C+ C N G YRC+C
Sbjct: 257 GVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQDPAACRPGRCVNLPGSYRCEC 316
Query: 522 PVGTVRSPSG 551
V PSG
Sbjct: 317 RPPWVPGPSG 326
Score = 80.6 bits (190), Expect = 3e-15
Identities = 43/119 (36%), Positives = 58/119 (48%), Gaps = 6/119 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
NT GSF+C C GY + DEC C NT+GSY CLC G+ L
Sbjct: 10 NTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRL-VG 68
Query: 186 GANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVC 350
G C+D+DEC +D C C N +GSY C C++G+ D C ++ + H + C
Sbjct: 69 GRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKEC 127
Score = 73.3 bits (172), Expect = 5e-13
Identities = 68/207 (32%), Positives = 90/207 (43%), Gaps = 24/207 (11%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSY---------- 146
R VN GS+RC C P + P+GR + + A R P +C + G
Sbjct: 304 RCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQRGEDGMCAGPLAGP 363
Query: 147 -----DCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECS-CEDGYEKRGD 308
DC CR G GA CR +H C S + ++ S G R +
Sbjct: 364 ALTFDDCCCRQGRGW---GAQCRPCPPRGAGSH-CPTSQSESNSFWDTSPLLLGKPPRDE 419
Query: 309 ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR----C 476
+ E +E C S GRCV G C CP G++LDA ARCVD DEC + + C
Sbjct: 420 DSSE--EDSDECRCVS-GRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLC 476
Query: 477 QAP-CRNYAGGYRCDCPVGTVRS-PSG 551
++ C N +G +RC C G RS P G
Sbjct: 477 KSERCVNTSGSFRCVCKAGFARSRPHG 503
Score = 67.7 bits (158), Expect = 3e-11
Identities = 58/194 (29%), Positives = 80/194 (41%), Gaps = 15/194 (7%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCH-NTDGSYDCLCRTGYELDEDG 188
N GS+ CVC G+ P + G +E V P + C+ N D + C + +
Sbjct: 93 NLQGSYVCVCDEGFTPT-QDQHGCEE--VEQPHHKKECYLNFDDTVFCDSVLATNVTQQE 149
Query: 189 ANCRDV----DECERDTHTCQQICSNTEGSYECSCEDGYEKRGD-------ACVDINECH 335
C D CE + C + S+ E C GY + + A DI+EC
Sbjct: 150 CCCSLGAGWGDHCE--IYPCP-VYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECM 206
Query: 336 EEG--VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ-APCRNYAGG 506
G +C G+CVN + C C +G+ D CVD DEC C+ C N GG
Sbjct: 207 LFGSEICKE-GKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGG 265
Query: 507 YRCDCPVGTVRSPS 548
YRC C SP+
Sbjct: 266 YRCACTPPAEYSPA 279
Score = 67.3 bits (157), Expect = 3e-11
Identities = 58/189 (30%), Positives = 76/189 (40%), Gaps = 15/189 (7%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR-PAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELD 179
+NT GS+RC+C G+R GR + DEC+ P C C N GSY C+C G+
Sbjct: 50 INTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPT 109
Query: 180 EDGANCRDVD------ECE---RDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINEC 332
+D C +V+ EC DT C + + EC C G GD C +I C
Sbjct: 110 QDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLG-AGWGDHC-EIYPC 167
Query: 333 HEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR--C-QAPCRNYAG 503
C + G + Y + A D DEC G C + C N
Sbjct: 168 PVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHR----DIDECMLFGSEICKEGKCVNTQP 223
Query: 504 GYRCDCPVG 530
GY C C G
Sbjct: 224 GYECYCKQG 232
Score = 59.3 bits (137), Expect = 9e-09
Identities = 33/90 (36%), Positives = 41/90 (45%), Gaps = 8/90 (8%)
Frame = +3
Query: 198 RDVDECERDTHTCQQI---CSNTEGSYECSCEDGYEKRGDA--CVDINECHE---EGVCP 353
RD D E D+ C+ + C G C C G++ CVDI+EC E G+
Sbjct: 417 RDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLC 476
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCV 443
RCVN GSFRCVC G+ CV
Sbjct: 477 KSERCVNTSGSFRCVCKAGFARSRPHGACV 506
Score = 50.0 bits (114), Expect = 5e-06
Identities = 33/99 (33%), Positives = 40/99 (40%), Gaps = 8/99 (8%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR--GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VNT + C C G+ G + DEC + +C NT G Y C C E
Sbjct: 219 VNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSP 278
Query: 183 DGANC-----RDVDECERDTHTCQQ-ICSNTEGSYECSC 281
C DVDEC+ D C+ C N GSY C C
Sbjct: 279 AQRQCLSPEEMDVDECQ-DPAACRPGRCVNLPGSYRCEC 316
>AK222891-1|BAD96611.1| 810|Homo sapiens egf-like module
containing, mucin-like, hormone receptor-like sequence 2
isofor protein.
Length = 810
Score = 99.1 bits (236), Expect = 9e-21
Identities = 56/159 (35%), Positives = 79/159 (49%), Gaps = 23/159 (14%)
Frame = +3
Query: 123 CHNTDGSYDCLCRTGYE--------LDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYE 272
C NT+GSYDC+C GYE +E C+DVDEC+++ C+ C NT GSY
Sbjct: 85 CWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYT 144
Query: 273 CSCEDGYEKRGD---ACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYR------LD 422
C C G++ + + C D+NEC + C S C+N +GS++C C G++
Sbjct: 145 CQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNG 204
Query: 423 AEGARCVDRDECAQ-TGRCQAP--CRNYAGGYRCDCPVG 530
C D DEC+ +C + C N G Y C C G
Sbjct: 205 PNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPG 243
Score = 91.5 bits (217), Expect = 2e-18
Identities = 55/159 (34%), Positives = 71/159 (44%), Gaps = 24/159 (15%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG----------RGVRGRDECAVRPPPCDQ--LCHNTDGSYDCL 155
NT GS+ CVC PGY P + DEC P C C NT GSY C
Sbjct: 87 NTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQ 146
Query: 156 CRTGYEL-DEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYE--------KR 302
C G++L ED C DV+EC + C C N GSY+C C G++
Sbjct: 147 CLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPN 206
Query: 303 GDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYR 416
C D++EC + C S C N +GS+ C C G++
Sbjct: 207 NTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 245
Score = 76.6 bits (180), Expect = 5e-14
Identities = 42/111 (37%), Positives = 54/111 (48%), Gaps = 13/111 (11%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR---GRDECAVRPPPCDQLCH--NTDGSYDCLCRTGYE 173
VNT+GS+ C C PG++ + +EC PC H N GSY C CR G++
Sbjct: 137 VNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ 196
Query: 174 L---DEDGAN---CRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKR 302
+G N C DVDEC H C +C NT GSY C C G++ R
Sbjct: 197 PIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPR 247
Score = 49.6 bits (113), Expect = 7e-06
Identities = 41/133 (30%), Positives = 53/133 (39%), Gaps = 24/133 (18%)
Frame = +3
Query: 219 RDTHTCQQIC---SNTEGSYECSCEDGYEKRGD-------ACVDINECH--EEGVCPSPG 362
+D+ C + C S+ + C C G+ + C DINEC + C
Sbjct: 24 QDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFS 83
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGAR---------CVDRDECAQTGR-CQA--PCRNYAGG 506
C N GS+ CVC GY GA+ C D DEC Q R C++ C N G
Sbjct: 84 DCWNTEGSYDCVCSPGYE-PVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGS 142
Query: 507 YRCDCPVGTVRSP 545
Y C C G P
Sbjct: 143 YTCQCLPGFKLKP 155
>AF114491-1|AAF21974.1| 823|Homo sapiens EGF-like module EMR2
protein.
Length = 823
Score = 99.1 bits (236), Expect = 9e-21
Identities = 56/159 (35%), Positives = 79/159 (49%), Gaps = 23/159 (14%)
Frame = +3
Query: 123 CHNTDGSYDCLCRTGYE--------LDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYE 272
C NT+GSYDC+C GYE +E C+DVDEC+++ C+ C NT GSY
Sbjct: 85 CWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYT 144
Query: 273 CSCEDGYEKRGD---ACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYR------LD 422
C C G++ + + C D+NEC + C S C+N +GS++C C G++
Sbjct: 145 CQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNG 204
Query: 423 AEGARCVDRDECAQ-TGRCQAP--CRNYAGGYRCDCPVG 530
C D DEC+ +C + C N G Y C C G
Sbjct: 205 PNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPG 243
Score = 91.5 bits (217), Expect = 2e-18
Identities = 55/159 (34%), Positives = 71/159 (44%), Gaps = 24/159 (15%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG----------RGVRGRDECAVRPPPCDQ--LCHNTDGSYDCL 155
NT GS+ CVC PGY P + DEC P C C NT GSY C
Sbjct: 87 NTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQ 146
Query: 156 CRTGYEL-DEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYE--------KR 302
C G++L ED C DV+EC + C C N GSY+C C G++
Sbjct: 147 CLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPN 206
Query: 303 GDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYR 416
C D++EC + C S C N +GS+ C C G++
Sbjct: 207 NTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 245
Score = 76.6 bits (180), Expect = 5e-14
Identities = 42/111 (37%), Positives = 54/111 (48%), Gaps = 13/111 (11%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR---GRDECAVRPPPCDQLCH--NTDGSYDCLCRTGYE 173
VNT+GS+ C C PG++ + +EC PC H N GSY C CR G++
Sbjct: 137 VNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ 196
Query: 174 L---DEDGAN---CRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKR 302
+G N C DVDEC H C +C NT GSY C C G++ R
Sbjct: 197 PIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPR 247
Score = 49.6 bits (113), Expect = 7e-06
Identities = 41/133 (30%), Positives = 53/133 (39%), Gaps = 24/133 (18%)
Frame = +3
Query: 219 RDTHTCQQIC---SNTEGSYECSCEDGYEKRGD-------ACVDINECH--EEGVCPSPG 362
+D+ C + C S+ + C C G+ + C DINEC + C
Sbjct: 24 QDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFS 83
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGAR---------CVDRDECAQTGR-CQA--PCRNYAGG 506
C N GS+ CVC GY GA+ C D DEC Q R C++ C N G
Sbjct: 84 DCWNTEGSYDCVCSPGYE-PVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGS 142
Query: 507 YRCDCPVGTVRSP 545
Y C C G P
Sbjct: 143 YTCQCLPGFKLKP 155
>AB065931-1|BAC06146.1| 837|Homo sapiens seven transmembrane helix
receptor protein.
Length = 837
Score = 99.1 bits (236), Expect = 9e-21
Identities = 56/159 (35%), Positives = 79/159 (49%), Gaps = 23/159 (14%)
Frame = +3
Query: 123 CHNTDGSYDCLCRTGYE--------LDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYE 272
C NT+GSYDC+C GYE +E C+DVDEC+++ C+ C NT GSY
Sbjct: 86 CWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYT 145
Query: 273 CSCEDGYEKRGD---ACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYR------LD 422
C C G++ + + C D+NEC + C S C+N +GS++C C G++
Sbjct: 146 CQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNG 205
Query: 423 AEGARCVDRDECAQ-TGRCQAP--CRNYAGGYRCDCPVG 530
C D DEC+ +C + C N G Y C C G
Sbjct: 206 PNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPG 244
Score = 91.5 bits (217), Expect = 2e-18
Identities = 55/159 (34%), Positives = 71/159 (44%), Gaps = 24/159 (15%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG----------RGVRGRDECAVRPPPCDQ--LCHNTDGSYDCL 155
NT GS+ CVC PGY P + DEC P C C NT GSY C
Sbjct: 88 NTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQ 147
Query: 156 CRTGYEL-DEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYE--------KR 302
C G++L ED C DV+EC + C C N GSY+C C G++
Sbjct: 148 CLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPN 207
Query: 303 GDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYR 416
C D++EC + C S C N +GS+ C C G++
Sbjct: 208 NTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 246
Score = 76.6 bits (180), Expect = 5e-14
Identities = 42/111 (37%), Positives = 54/111 (48%), Gaps = 13/111 (11%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVR---GRDECAVRPPPCDQLCH--NTDGSYDCLCRTGYE 173
VNT+GS+ C C PG++ + +EC PC H N GSY C CR G++
Sbjct: 138 VNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ 197
Query: 174 L---DEDGAN---CRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKR 302
+G N C DVDEC H C +C NT GSY C C G++ R
Sbjct: 198 PIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPR 248
Score = 49.6 bits (113), Expect = 7e-06
Identities = 41/133 (30%), Positives = 53/133 (39%), Gaps = 24/133 (18%)
Frame = +3
Query: 219 RDTHTCQQIC---SNTEGSYECSCEDGYEKRGD-------ACVDINECH--EEGVCPSPG 362
+D+ C + C S+ + C C G+ + C DINEC + C
Sbjct: 25 QDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFS 84
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGAR---------CVDRDECAQTGR-CQA--PCRNYAGG 506
C N GS+ CVC GY GA+ C D DEC Q R C++ C N G
Sbjct: 85 DCWNTEGSYDCVCSPGYE-PVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGS 143
Query: 507 YRCDCPVGTVRSP 545
Y C C G P
Sbjct: 144 YTCQCLPGFKLKP 156
>X05495-1|CAA29045.1| 575|Homo sapiens thrombomodulin protein.
Length = 575
Score = 98.7 bits (235), Expect = 1e-20
Identities = 61/171 (35%), Positives = 76/171 (44%), Gaps = 4/171 (2%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
GS+ C+C GYR A R D +C + P PC Q C NT G ++C C Y+L DG
Sbjct: 304 GSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDL-VDGEC 362
Query: 195 CRDVDECERDTHTCQQICSN-TEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRC- 368
VD C R C+ C + SY C C +G+ + CP+ C
Sbjct: 363 VEPVDPCFRAN--CEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPAD--CD 418
Query: 369 VNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
N S C CP GY LD +G C D DEC G C C N G + C C
Sbjct: 419 PNTQAS--CECPEGYILD-DGFICTDIDECENGGFCSGVCHNLPGTFECIC 466
Score = 91.1 bits (216), Expect = 2e-18
Identities = 62/181 (34%), Positives = 81/181 (44%), Gaps = 9/181 (4%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCH-----NTD--GSYDCLCRTGYELD 179
G+ RC C G A GR A C+ LC N D GSY C+C TGY L
Sbjct: 261 GAPRCQCPAG---AALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLA 317
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCPS 356
D C DVD+C + C Q C NT+G +EC C Y+ CV+ ++ C C
Sbjct: 318 ADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECVEPVDPCFRAN-CEY 376
Query: 357 PGRCVNLLGSFRCVCPRGYR-LDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGT 533
+ +N S+ CVC G+ + E RC + C QT C A C C+CP G
Sbjct: 377 QCQPLNQT-SYLCVCAEGFAPIPHEPHRC--QMFCNQTA-CPADCDPNTQA-SCECPEGY 431
Query: 534 V 536
+
Sbjct: 432 I 432
Score = 80.6 bits (190), Expect = 3e-15
Identities = 53/179 (29%), Positives = 69/179 (38%), Gaps = 8/179 (4%)
Frame = +3
Query: 33 CVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDV 206
C PG R G +C+V C+ C+ G+ C C G L DG +C
Sbjct: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSC-TA 282
Query: 207 DECERDTHTCQQIC---SNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCV 371
+ C+ C + GSY C CE GY D C D+++C E P P RCV
Sbjct: 283 SATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILE-PSPCPQRCV 341
Query: 372 NLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNY-AGGYRCDCPVGTVRSP 545
N G F C C Y D CV+ + C+ C+ Y C C G P
Sbjct: 342 NTQGGFECHCYPNY--DLVDGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIP 398
Score = 63.7 bits (148), Expect = 4e-10
Identities = 48/138 (34%), Positives = 60/138 (43%), Gaps = 5/138 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPA-GRGVRGRDECAVRPPPCDQLCHN-TDGSYDCLCRTGY-E 173
R VNT G F C C P Y G V D C C+ C SY C+C G+
Sbjct: 339 RCVNTQGGFECHCYPNYDLVDGECVEPVDPCF--RANCEYQCQPLNQTSYLCVCAEGFAP 396
Query: 174 LDEDGANCRDVDECERDTHTCQQICS-NTEGSYECSCEDGY-EKRGDACVDINECHEEGV 347
+ + C+ C + C C NT+ S C C +GY G C DI+EC G
Sbjct: 397 IPHEPHRCQMF--CNQT--ACPADCDPNTQAS--CECPEGYILDDGFICTDIDECENGGF 450
Query: 348 CPSPGRCVNLLGSFRCVC 401
C G C NL G+F C+C
Sbjct: 451 C--SGVCHNLPGTFECIC 466
>M16552-1|AAB59508.1| 575|Homo sapiens THBD protein.
Length = 575
Score = 98.7 bits (235), Expect = 1e-20
Identities = 61/171 (35%), Positives = 76/171 (44%), Gaps = 4/171 (2%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
GS+ C+C GYR A R D +C + P PC Q C NT G ++C C Y+L DG
Sbjct: 304 GSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDL-VDGEC 362
Query: 195 CRDVDECERDTHTCQQICSN-TEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRC- 368
VD C R C+ C + SY C C +G+ + CP+ C
Sbjct: 363 VEPVDPCFRAN--CEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPAD--CD 418
Query: 369 VNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
N S C CP GY LD +G C D DEC G C C N G + C C
Sbjct: 419 PNTQAS--CECPEGYILD-DGFICTDIDECENGGFCSGVCHNLPGTFECIC 466
Score = 91.1 bits (216), Expect = 2e-18
Identities = 62/181 (34%), Positives = 81/181 (44%), Gaps = 9/181 (4%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCH-----NTD--GSYDCLCRTGYELD 179
G+ RC C G A GR A C+ LC N D GSY C+C TGY L
Sbjct: 261 GAPRCQCPAG---AALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLA 317
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCPS 356
D C DVD+C + C Q C NT+G +EC C Y+ CV+ ++ C C
Sbjct: 318 ADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECVEPVDPCFRAN-CEY 376
Query: 357 PGRCVNLLGSFRCVCPRGYR-LDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGT 533
+ +N S+ CVC G+ + E RC + C QT C A C C+CP G
Sbjct: 377 QCQPLNQT-SYLCVCAEGFAPIPHEPHRC--QMFCNQTA-CPADCDPNTQA-SCECPEGY 431
Query: 534 V 536
+
Sbjct: 432 I 432
Score = 80.6 bits (190), Expect = 3e-15
Identities = 53/179 (29%), Positives = 69/179 (38%), Gaps = 8/179 (4%)
Frame = +3
Query: 33 CVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDV 206
C PG R G +C+V C+ C+ G+ C C G L DG +C
Sbjct: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSC-TA 282
Query: 207 DECERDTHTCQQIC---SNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCV 371
+ C+ C + GSY C CE GY D C D+++C E P P RCV
Sbjct: 283 SATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILE-PSPCPQRCV 341
Query: 372 NLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNY-AGGYRCDCPVGTVRSP 545
N G F C C Y D CV+ + C+ C+ Y C C G P
Sbjct: 342 NTQGGFECHCYPNY--DLVDGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIP 398
Score = 63.7 bits (148), Expect = 4e-10
Identities = 48/138 (34%), Positives = 60/138 (43%), Gaps = 5/138 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPA-GRGVRGRDECAVRPPPCDQLCHN-TDGSYDCLCRTGY-E 173
R VNT G F C C P Y G V D C C+ C SY C+C G+
Sbjct: 339 RCVNTQGGFECHCYPNYDLVDGECVEPVDPCF--RANCEYQCQPLNQTSYLCVCAEGFAP 396
Query: 174 LDEDGANCRDVDECERDTHTCQQICS-NTEGSYECSCEDGY-EKRGDACVDINECHEEGV 347
+ + C+ C + C C NT+ S C C +GY G C DI+EC G
Sbjct: 397 IPHEPHRCQMF--CNQT--ACPADCDPNTQAS--CECPEGYILDDGFICTDIDECENGGF 450
Query: 348 CPSPGRCVNLLGSFRCVC 401
C G C NL G+F C+C
Sbjct: 451 C--SGVCHNLPGTFECIC 466
>J02973-1|AAA61175.1| 575|Homo sapiens THBD protein.
Length = 575
Score = 98.7 bits (235), Expect = 1e-20
Identities = 61/171 (35%), Positives = 76/171 (44%), Gaps = 4/171 (2%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
GS+ C+C GYR A R D +C + P PC Q C NT G ++C C Y+L DG
Sbjct: 304 GSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDL-VDGEC 362
Query: 195 CRDVDECERDTHTCQQICSN-TEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRC- 368
VD C R C+ C + SY C C +G+ + CP+ C
Sbjct: 363 VEPVDPCFRAN--CEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPAD--CD 418
Query: 369 VNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
N S C CP GY LD +G C D DEC G C C N G + C C
Sbjct: 419 PNTQAS--CECPEGYILD-DGFICTDIDECENGGFCSGVCHNLPGTFECIC 466
Score = 91.1 bits (216), Expect = 2e-18
Identities = 62/181 (34%), Positives = 81/181 (44%), Gaps = 9/181 (4%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCH-----NTD--GSYDCLCRTGYELD 179
G+ RC C G A GR A C+ LC N D GSY C+C TGY L
Sbjct: 261 GAPRCQCPAG---AALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLA 317
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCPS 356
D C DVD+C + C Q C NT+G +EC C Y+ CV+ ++ C C
Sbjct: 318 ADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECVEPVDPCFRAN-CEY 376
Query: 357 PGRCVNLLGSFRCVCPRGYR-LDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGT 533
+ +N S+ CVC G+ + E RC + C QT C A C C+CP G
Sbjct: 377 QCQPLNQT-SYLCVCAEGFAPIPHEPHRC--QMFCNQTA-CPADCDPNTQA-SCECPEGY 431
Query: 534 V 536
+
Sbjct: 432 I 432
Score = 80.6 bits (190), Expect = 3e-15
Identities = 53/179 (29%), Positives = 69/179 (38%), Gaps = 8/179 (4%)
Frame = +3
Query: 33 CVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDV 206
C PG R G +C+V C+ C+ G+ C C G L DG +C
Sbjct: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSC-TA 282
Query: 207 DECERDTHTCQQIC---SNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCV 371
+ C+ C + GSY C CE GY D C D+++C E P P RCV
Sbjct: 283 SATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILE-PSPCPQRCV 341
Query: 372 NLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNY-AGGYRCDCPVGTVRSP 545
N G F C C Y D CV+ + C+ C+ Y C C G P
Sbjct: 342 NTQGGFECHCYPNY--DLVDGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIP 398
Score = 63.7 bits (148), Expect = 4e-10
Identities = 48/138 (34%), Positives = 60/138 (43%), Gaps = 5/138 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPA-GRGVRGRDECAVRPPPCDQLCHN-TDGSYDCLCRTGY-E 173
R VNT G F C C P Y G V D C C+ C SY C+C G+
Sbjct: 339 RCVNTQGGFECHCYPNYDLVDGECVEPVDPCF--RANCEYQCQPLNQTSYLCVCAEGFAP 396
Query: 174 LDEDGANCRDVDECERDTHTCQQICS-NTEGSYECSCEDGY-EKRGDACVDINECHEEGV 347
+ + C+ C + C C NT+ S C C +GY G C DI+EC G
Sbjct: 397 IPHEPHRCQMF--CNQT--ACPADCDPNTQAS--CECPEGYILDDGFICTDIDECENGGF 450
Query: 348 CPSPGRCVNLLGSFRCVC 401
C G C NL G+F C+C
Sbjct: 451 C--SGVCHNLPGTFECIC 466
>D00210-1|BAA00149.1| 575|Homo sapiens thrombomodulin precursor
protein.
Length = 575
Score = 98.7 bits (235), Expect = 1e-20
Identities = 61/171 (35%), Positives = 76/171 (44%), Gaps = 4/171 (2%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
GS+ C+C GYR A R D +C + P PC Q C NT G ++C C Y+L DG
Sbjct: 304 GSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDL-VDGEC 362
Query: 195 CRDVDECERDTHTCQQICSN-TEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRC- 368
VD C R C+ C + SY C C +G+ + CP+ C
Sbjct: 363 VEPVDPCFRAN--CEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPAD--CD 418
Query: 369 VNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
N S C CP GY LD +G C D DEC G C C N G + C C
Sbjct: 419 PNTQAS--CECPEGYILD-DGFICTDIDECENGGFCSGVCHNLPGTFECIC 466
Score = 91.1 bits (216), Expect = 2e-18
Identities = 62/181 (34%), Positives = 81/181 (44%), Gaps = 9/181 (4%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCH-----NTD--GSYDCLCRTGYELD 179
G+ RC C G A GR A C+ LC N D GSY C+C TGY L
Sbjct: 261 GAPRCQCPAG---AALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLA 317
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCPS 356
D C DVD+C + C Q C NT+G +EC C Y+ CV+ ++ C C
Sbjct: 318 ADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECVEPVDPCFRAN-CEY 376
Query: 357 PGRCVNLLGSFRCVCPRGYR-LDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGT 533
+ +N S+ CVC G+ + E RC + C QT C A C C+CP G
Sbjct: 377 QCQPLNQT-SYLCVCAEGFAPIPHEPHRC--QMFCNQTA-CPADCDPNTQA-SCECPEGY 431
Query: 534 V 536
+
Sbjct: 432 I 432
Score = 80.6 bits (190), Expect = 3e-15
Identities = 53/179 (29%), Positives = 69/179 (38%), Gaps = 8/179 (4%)
Frame = +3
Query: 33 CVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDV 206
C PG R G +C+V C+ C+ G+ C C G L DG +C
Sbjct: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSC-TA 282
Query: 207 DECERDTHTCQQIC---SNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCV 371
+ C+ C + GSY C CE GY D C D+++C E P P RCV
Sbjct: 283 SATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILE-PSPCPQRCV 341
Query: 372 NLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNY-AGGYRCDCPVGTVRSP 545
N G F C C Y D CV+ + C+ C+ Y C C G P
Sbjct: 342 NTQGGFECHCYPNY--DLVDGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIP 398
Score = 63.7 bits (148), Expect = 4e-10
Identities = 48/138 (34%), Positives = 60/138 (43%), Gaps = 5/138 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPA-GRGVRGRDECAVRPPPCDQLCHN-TDGSYDCLCRTGY-E 173
R VNT G F C C P Y G V D C C+ C SY C+C G+
Sbjct: 339 RCVNTQGGFECHCYPNYDLVDGECVEPVDPCF--RANCEYQCQPLNQTSYLCVCAEGFAP 396
Query: 174 LDEDGANCRDVDECERDTHTCQQICS-NTEGSYECSCEDGY-EKRGDACVDINECHEEGV 347
+ + C+ C + C C NT+ S C C +GY G C DI+EC G
Sbjct: 397 IPHEPHRCQMF--CNQT--ACPADCDPNTQAS--CECPEGYILDDGFICTDIDECENGGF 450
Query: 348 CPSPGRCVNLLGSFRCVC 401
C G C NL G+F C+C
Sbjct: 451 C--SGVCHNLPGTFECIC 466
>BC053357-1|AAH53357.1| 575|Homo sapiens thrombomodulin protein.
Length = 575
Score = 98.7 bits (235), Expect = 1e-20
Identities = 61/171 (35%), Positives = 76/171 (44%), Gaps = 4/171 (2%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
GS+ C+C GYR A R D +C + P PC Q C NT G ++C C Y+L DG
Sbjct: 304 GSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDL-VDGEC 362
Query: 195 CRDVDECERDTHTCQQICSN-TEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRC- 368
VD C R C+ C + SY C C +G+ + CP+ C
Sbjct: 363 VEPVDPCFRAN--CEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPAD--CD 418
Query: 369 VNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
N S C CP GY LD +G C D DEC G C C N G + C C
Sbjct: 419 PNTQAS--CECPEGYILD-DGFICTDIDECENGGFCSGVCHNLPGTFECIC 466
Score = 91.1 bits (216), Expect = 2e-18
Identities = 62/181 (34%), Positives = 81/181 (44%), Gaps = 9/181 (4%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCH-----NTD--GSYDCLCRTGYELD 179
G+ RC C G A GR A C+ LC N D GSY C+C TGY L
Sbjct: 261 GAPRCQCPAG---AALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLA 317
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCPS 356
D C DVD+C + C Q C NT+G +EC C Y+ CV+ ++ C C
Sbjct: 318 ADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECVEPVDPCFRAN-CEY 376
Query: 357 PGRCVNLLGSFRCVCPRGYR-LDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGT 533
+ +N S+ CVC G+ + E RC + C QT C A C C+CP G
Sbjct: 377 QCQPLNQT-SYLCVCAEGFAPIPHEPHRC--QMFCNQTA-CPADCDPNTQA-SCECPEGY 431
Query: 534 V 536
+
Sbjct: 432 I 432
Score = 80.6 bits (190), Expect = 3e-15
Identities = 53/179 (29%), Positives = 69/179 (38%), Gaps = 8/179 (4%)
Frame = +3
Query: 33 CVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDV 206
C PG R G +C+V C+ C+ G+ C C G L DG +C
Sbjct: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSC-TA 282
Query: 207 DECERDTHTCQQIC---SNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCV 371
+ C+ C + GSY C CE GY D C D+++C E P P RCV
Sbjct: 283 SATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILE-PSPCPQRCV 341
Query: 372 NLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNY-AGGYRCDCPVGTVRSP 545
N G F C C Y D CV+ + C+ C+ Y C C G P
Sbjct: 342 NTQGGFECHCYPNY--DLVDGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIP 398
Score = 63.7 bits (148), Expect = 4e-10
Identities = 48/138 (34%), Positives = 60/138 (43%), Gaps = 5/138 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPA-GRGVRGRDECAVRPPPCDQLCHN-TDGSYDCLCRTGY-E 173
R VNT G F C C P Y G V D C C+ C SY C+C G+
Sbjct: 339 RCVNTQGGFECHCYPNYDLVDGECVEPVDPCF--RANCEYQCQPLNQTSYLCVCAEGFAP 396
Query: 174 LDEDGANCRDVDECERDTHTCQQICS-NTEGSYECSCEDGY-EKRGDACVDINECHEEGV 347
+ + C+ C + C C NT+ S C C +GY G C DI+EC G
Sbjct: 397 IPHEPHRCQMF--CNQT--ACPADCDPNTQAS--CECPEGYILDDGFICTDIDECENGGF 450
Query: 348 CPSPGRCVNLLGSFRCVC 401
C G C NL G+F C+C
Sbjct: 451 C--SGVCHNLPGTFECIC 466
>BC035602-1|AAH35602.2| 575|Homo sapiens thrombomodulin protein.
Length = 575
Score = 98.7 bits (235), Expect = 1e-20
Identities = 61/171 (35%), Positives = 76/171 (44%), Gaps = 4/171 (2%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
GS+ C+C GYR A R D +C + P PC Q C NT G ++C C Y+L DG
Sbjct: 304 GSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDL-VDGEC 362
Query: 195 CRDVDECERDTHTCQQICSN-TEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRC- 368
VD C R C+ C + SY C C +G+ + CP+ C
Sbjct: 363 VEPVDPCFRAN--CEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPAD--CD 418
Query: 369 VNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
N S C CP GY LD +G C D DEC G C C N G + C C
Sbjct: 419 PNTQAS--CECPEGYILD-DGFICTDIDECENGGFCSGVCHNLPGTFECIC 466
Score = 91.1 bits (216), Expect = 2e-18
Identities = 62/181 (34%), Positives = 81/181 (44%), Gaps = 9/181 (4%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCH-----NTD--GSYDCLCRTGYELD 179
G+ RC C G A GR A C+ LC N D GSY C+C TGY L
Sbjct: 261 GAPRCQCPAG---AALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLA 317
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCPS 356
D C DVD+C + C Q C NT+G +EC C Y+ CV+ ++ C C
Sbjct: 318 ADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECVEPVDPCFRAN-CEY 376
Query: 357 PGRCVNLLGSFRCVCPRGYR-LDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGT 533
+ +N S+ CVC G+ + E RC + C QT C A C C+CP G
Sbjct: 377 QCQPLNQT-SYLCVCAEGFAPIPHEPHRC--QMFCNQTA-CPADCDPNTQA-SCECPEGY 431
Query: 534 V 536
+
Sbjct: 432 I 432
Score = 80.6 bits (190), Expect = 3e-15
Identities = 53/179 (29%), Positives = 69/179 (38%), Gaps = 8/179 (4%)
Frame = +3
Query: 33 CVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDV 206
C PG R G +C+V C+ C+ G+ C C G L DG +C
Sbjct: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSC-TA 282
Query: 207 DECERDTHTCQQIC---SNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCV 371
+ C+ C + GSY C CE GY D C D+++C E P P RCV
Sbjct: 283 SATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILE-PSPCPQRCV 341
Query: 372 NLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNY-AGGYRCDCPVGTVRSP 545
N G F C C Y D CV+ + C+ C+ Y C C G P
Sbjct: 342 NTQGGFECHCYPNY--DLVDGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIP 398
Score = 63.7 bits (148), Expect = 4e-10
Identities = 48/138 (34%), Positives = 60/138 (43%), Gaps = 5/138 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPA-GRGVRGRDECAVRPPPCDQLCHN-TDGSYDCLCRTGY-E 173
R VNT G F C C P Y G V D C C+ C SY C+C G+
Sbjct: 339 RCVNTQGGFECHCYPNYDLVDGECVEPVDPCF--RANCEYQCQPLNQTSYLCVCAEGFAP 396
Query: 174 LDEDGANCRDVDECERDTHTCQQICS-NTEGSYECSCEDGY-EKRGDACVDINECHEEGV 347
+ + C+ C + C C NT+ S C C +GY G C DI+EC G
Sbjct: 397 IPHEPHRCQMF--CNQT--ACPADCDPNTQAS--CECPEGYILDDGFICTDIDECENGGF 450
Query: 348 CPSPGRCVNLLGSFRCVC 401
C G C NL G+F C+C
Sbjct: 451 C--SGVCHNLPGTFECIC 466
>AL049651-2|CAB51954.1| 575|Homo sapiens thrombomodulin protein.
Length = 575
Score = 98.7 bits (235), Expect = 1e-20
Identities = 61/171 (35%), Positives = 76/171 (44%), Gaps = 4/171 (2%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
GS+ C+C GYR A R D +C + P PC Q C NT G ++C C Y+L DG
Sbjct: 304 GSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDL-VDGEC 362
Query: 195 CRDVDECERDTHTCQQICSN-TEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRC- 368
VD C R C+ C + SY C C +G+ + CP+ C
Sbjct: 363 VEPVDPCFRAN--CEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPAD--CD 418
Query: 369 VNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
N S C CP GY LD +G C D DEC G C C N G + C C
Sbjct: 419 PNTQAS--CECPEGYILD-DGFICTDIDECENGGFCSGVCHNLPGTFECIC 466
Score = 91.1 bits (216), Expect = 2e-18
Identities = 62/181 (34%), Positives = 81/181 (44%), Gaps = 9/181 (4%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCH-----NTD--GSYDCLCRTGYELD 179
G+ RC C G A GR A C+ LC N D GSY C+C TGY L
Sbjct: 261 GAPRCQCPAG---AALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLA 317
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCPS 356
D C DVD+C + C Q C NT+G +EC C Y+ CV+ ++ C C
Sbjct: 318 ADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECVEPVDPCFRAN-CEY 376
Query: 357 PGRCVNLLGSFRCVCPRGYR-LDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGT 533
+ +N S+ CVC G+ + E RC + C QT C A C C+CP G
Sbjct: 377 QCQPLNQT-SYLCVCAEGFAPIPHEPHRC--QMFCNQTA-CPADCDPNTQA-SCECPEGY 431
Query: 534 V 536
+
Sbjct: 432 I 432
Score = 80.6 bits (190), Expect = 3e-15
Identities = 53/179 (29%), Positives = 69/179 (38%), Gaps = 8/179 (4%)
Frame = +3
Query: 33 CVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDV 206
C PG R G +C+V C+ C+ G+ C C G L DG +C
Sbjct: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSC-TA 282
Query: 207 DECERDTHTCQQIC---SNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCV 371
+ C+ C + GSY C CE GY D C D+++C E P P RCV
Sbjct: 283 SATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILE-PSPCPQRCV 341
Query: 372 NLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNY-AGGYRCDCPVGTVRSP 545
N G F C C Y D CV+ + C+ C+ Y C C G P
Sbjct: 342 NTQGGFECHCYPNY--DLVDGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIP 398
Score = 63.7 bits (148), Expect = 4e-10
Identities = 48/138 (34%), Positives = 60/138 (43%), Gaps = 5/138 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPA-GRGVRGRDECAVRPPPCDQLCHN-TDGSYDCLCRTGY-E 173
R VNT G F C C P Y G V D C C+ C SY C+C G+
Sbjct: 339 RCVNTQGGFECHCYPNYDLVDGECVEPVDPCF--RANCEYQCQPLNQTSYLCVCAEGFAP 396
Query: 174 LDEDGANCRDVDECERDTHTCQQICS-NTEGSYECSCEDGY-EKRGDACVDINECHEEGV 347
+ + C+ C + C C NT+ S C C +GY G C DI+EC G
Sbjct: 397 IPHEPHRCQMF--CNQT--ACPADCDPNTQAS--CECPEGYILDDGFICTDIDECENGGF 450
Query: 348 CPSPGRCVNLLGSFRCVC 401
C G C NL G+F C+C
Sbjct: 451 C--SGVCHNLPGTFECIC 466
>AF495471-1|AAM03232.1| 575|Homo sapiens thrombomodulin protein.
Length = 575
Score = 98.7 bits (235), Expect = 1e-20
Identities = 61/171 (35%), Positives = 76/171 (44%), Gaps = 4/171 (2%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
GS+ C+C GYR A R D +C + P PC Q C NT G ++C C Y+L DG
Sbjct: 304 GSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDL-VDGEC 362
Query: 195 CRDVDECERDTHTCQQICSN-TEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRC- 368
VD C R C+ C + SY C C +G+ + CP+ C
Sbjct: 363 VEPVDPCFRAN--CEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPAD--CD 418
Query: 369 VNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
N S C CP GY LD +G C D DEC G C C N G + C C
Sbjct: 419 PNTQAS--CECPEGYILD-DGFICTDIDECENGGFCSGVCHNLPGTFECIC 466
Score = 91.1 bits (216), Expect = 2e-18
Identities = 62/181 (34%), Positives = 81/181 (44%), Gaps = 9/181 (4%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCH-----NTD--GSYDCLCRTGYELD 179
G+ RC C G A GR A C+ LC N D GSY C+C TGY L
Sbjct: 261 GAPRCQCPAG---AALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLA 317
Query: 180 EDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCPS 356
D C DVD+C + C Q C NT+G +EC C Y+ CV+ ++ C C
Sbjct: 318 ADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECVEPVDPCFRAN-CEY 376
Query: 357 PGRCVNLLGSFRCVCPRGYR-LDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGT 533
+ +N S+ CVC G+ + E RC + C QT C A C C+CP G
Sbjct: 377 QCQPLNQT-SYLCVCAEGFAPIPHEPHRC--QMFCNQTA-CPADCDPNTQA-SCECPEGY 431
Query: 534 V 536
+
Sbjct: 432 I 432
Score = 80.6 bits (190), Expect = 3e-15
Identities = 53/179 (29%), Positives = 69/179 (38%), Gaps = 8/179 (4%)
Frame = +3
Query: 33 CVCGPGYRPA--GRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDV 206
C PG R G +C+V C+ C+ G+ C C G L DG +C
Sbjct: 224 CTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSC-TA 282
Query: 207 DECERDTHTCQQIC---SNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCV 371
+ C+ C + GSY C CE GY D C D+++C E P P RCV
Sbjct: 283 SATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILE-PSPCPQRCV 341
Query: 372 NLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNY-AGGYRCDCPVGTVRSP 545
N G F C C Y D CV+ + C+ C+ Y C C G P
Sbjct: 342 NTQGGFECHCYPNY--DLVDGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIP 398
Score = 63.7 bits (148), Expect = 4e-10
Identities = 48/138 (34%), Positives = 60/138 (43%), Gaps = 5/138 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPA-GRGVRGRDECAVRPPPCDQLCHN-TDGSYDCLCRTGY-E 173
R VNT G F C C P Y G V D C C+ C SY C+C G+
Sbjct: 339 RCVNTQGGFECHCYPNYDLVDGECVEPVDPCF--RANCEYQCQPLNQTSYLCVCAEGFAP 396
Query: 174 LDEDGANCRDVDECERDTHTCQQICS-NTEGSYECSCEDGY-EKRGDACVDINECHEEGV 347
+ + C+ C + C C NT+ S C C +GY G C DI+EC G
Sbjct: 397 IPHEPHRCQMF--CNQT--ACPADCDPNTQAS--CECPEGYILDDGFICTDIDECENGGF 450
Query: 348 CPSPGRCVNLLGSFRCVC 401
C G C NL G+F C+C
Sbjct: 451 C--SGVCHNLPGTFECIC 466
>X82245-1|CAA57709.1| 1246|Homo sapiens nidogen protein.
Length = 1246
Score = 98.3 bits (234), Expect = 2e-20
Identities = 58/163 (35%), Positives = 78/163 (47%), Gaps = 12/163 (7%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANCR 200
F C C G+R GR DEC+ +P C +C+N G++ C C GY+ ++G
Sbjct: 692 FTCECSIGFRGDGRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVA 751
Query: 201 DVDE-----CERDTHTC----QQICSNTEGS-YECSCEDGYEKRGDACVDINECHEEGVC 350
VD+ CE H C + C T GS Y CSC G+ G AC D++EC + C
Sbjct: 752 VVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGFSGDGQACQDVDEC-QPSRC 810
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ 479
C N GSF C C GY+ +G RCV + + RCQ
Sbjct: 811 HPDAFCYNTPGSFTCQCKPGYQ--GDGFRCVPGE--VEKTRCQ 849
Score = 64.1 bits (149), Expect = 3e-10
Identities = 39/114 (34%), Positives = 50/114 (43%), Gaps = 12/114 (10%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGV-------RGRDECAVRPPPCD-----QLCHNTDGSYDCL 155
N G+FRC C GY+ + G R + C CD Q + SY C
Sbjct: 728 NHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCS 787
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV 317
C G+ DG C+DVDEC+ C NT GS+ C C+ GY+ G CV
Sbjct: 788 CLPGFS--GDGQACQDVDECQPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCV 839
Score = 40.7 bits (91), Expect = 0.003
Identities = 23/58 (39%), Positives = 29/58 (50%), Gaps = 3/58 (5%)
Frame = +3
Query: 387 FRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAP--CRNYAGGYRCDCPVGTVRSPSG 551
F C C G+R D G C D DEC+ Q C + C N+ G +RC+C G S G
Sbjct: 692 FTCECSIGFRGD--GRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEG 747
>M30269-1|AAA59932.1| 1247|Homo sapiens nidogen protein.
Length = 1247
Score = 98.3 bits (234), Expect = 2e-20
Identities = 58/163 (35%), Positives = 78/163 (47%), Gaps = 12/163 (7%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANCR 200
F C C G+R GR DEC+ +P C +C+N G++ C C GY+ ++G
Sbjct: 693 FTCECSIGFRGDGRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVA 752
Query: 201 DVDE-----CERDTHTC----QQICSNTEGS-YECSCEDGYEKRGDACVDINECHEEGVC 350
VD+ CE H C + C T GS Y CSC G+ G AC D++EC + C
Sbjct: 753 VVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGFSGDGQACQDVDEC-QPSRC 811
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ 479
C N GSF C C GY+ +G RCV + + RCQ
Sbjct: 812 HPDAFCYNTPGSFTCQCKPGYQ--GDGFRCVPGE--VEKTRCQ 850
Score = 64.1 bits (149), Expect = 3e-10
Identities = 39/114 (34%), Positives = 50/114 (43%), Gaps = 12/114 (10%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGV-------RGRDECAVRPPPCD-----QLCHNTDGSYDCL 155
N G+FRC C GY+ + G R + C CD Q + SY C
Sbjct: 729 NHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCS 788
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV 317
C G+ DG C+DVDEC+ C NT GS+ C C+ GY+ G CV
Sbjct: 789 CLPGFS--GDGQACQDVDECQPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCV 840
Score = 40.7 bits (91), Expect = 0.003
Identities = 23/58 (39%), Positives = 29/58 (50%), Gaps = 3/58 (5%)
Frame = +3
Query: 387 FRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAP--CRNYAGGYRCDCPVGTVRSPSG 551
F C C G+R D G C D DEC+ Q C + C N+ G +RC+C G S G
Sbjct: 693 FTCECSIGFRGD--GRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEG 748
>M27445-1|AAA57261.1| 581|Homo sapiens nidogen protein.
Length = 581
Score = 98.3 bits (234), Expect = 2e-20
Identities = 58/163 (35%), Positives = 78/163 (47%), Gaps = 12/163 (7%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANCR 200
F C C G+R GR DEC+ +P C +C+N G++ C C GY+ ++G
Sbjct: 27 FTCECSIGFRGDGRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVA 86
Query: 201 DVDE-----CERDTHTC----QQICSNTEGS-YECSCEDGYEKRGDACVDINECHEEGVC 350
VD+ CE H C + C T GS Y CSC G+ G AC D++EC + C
Sbjct: 87 VVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGFSGDGQACQDVDEC-QPSRC 145
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ 479
C N GSF C C GY+ +G RCV + + RCQ
Sbjct: 146 HPDAFCYNTPGSFTCQCKPGYQ--GDGFRCVPGE--VEKTRCQ 184
Score = 64.1 bits (149), Expect = 3e-10
Identities = 39/114 (34%), Positives = 50/114 (43%), Gaps = 12/114 (10%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGV-------RGRDECAVRPPPCD-----QLCHNTDGSYDCL 155
N G+FRC C GY+ + G R + C CD Q + SY C
Sbjct: 63 NHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCS 122
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV 317
C G+ DG C+DVDEC+ C NT GS+ C C+ GY+ G CV
Sbjct: 123 CLPGFS--GDGQACQDVDECQPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCV 174
Score = 40.7 bits (91), Expect = 0.003
Identities = 23/58 (39%), Positives = 29/58 (50%), Gaps = 3/58 (5%)
Frame = +3
Query: 387 FRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAP--CRNYAGGYRCDCPVGTVRSPSG 551
F C C G+R D G C D DEC+ Q C + C N+ G +RC+C G S G
Sbjct: 27 FTCECSIGFRGD--GRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEG 82
>AL139161-2|CAI23422.1| 1247|Homo sapiens nidogen 1 protein.
Length = 1247
Score = 98.3 bits (234), Expect = 2e-20
Identities = 58/163 (35%), Positives = 78/163 (47%), Gaps = 12/163 (7%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANCR 200
F C C G+R GR DEC+ +P C +C+N G++ C C GY+ ++G
Sbjct: 693 FTCECSIGFRGDGRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVA 752
Query: 201 DVDE-----CERDTHTC----QQICSNTEGS-YECSCEDGYEKRGDACVDINECHEEGVC 350
VD+ CE H C + C T GS Y CSC G+ G AC D++EC + C
Sbjct: 753 VVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGFSGDGQACQDVDEC-QPSRC 811
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ 479
C N GSF C C GY+ +G RCV + + RCQ
Sbjct: 812 HPDAFCYNTPGSFTCQCKPGYQ--GDGFRCVPGE--VEKTRCQ 850
Score = 64.1 bits (149), Expect = 3e-10
Identities = 39/114 (34%), Positives = 50/114 (43%), Gaps = 12/114 (10%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGV-------RGRDECAVRPPPCD-----QLCHNTDGSYDCL 155
N G+FRC C GY+ + G R + C CD Q + SY C
Sbjct: 729 NHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCS 788
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV 317
C G+ DG C+DVDEC+ C NT GS+ C C+ GY+ G CV
Sbjct: 789 CLPGFS--GDGQACQDVDECQPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCV 840
Score = 40.7 bits (91), Expect = 0.003
Identities = 23/58 (39%), Positives = 29/58 (50%), Gaps = 3/58 (5%)
Frame = +3
Query: 387 FRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAP--CRNYAGGYRCDCPVGTVRSPSG 551
F C C G+R D G C D DEC+ Q C + C N+ G +RC+C G S G
Sbjct: 693 FTCECSIGFRGD--GRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEG 748
>AL122018-2|CAI22681.1| 1247|Homo sapiens nidogen 1 protein.
Length = 1247
Score = 98.3 bits (234), Expect = 2e-20
Identities = 58/163 (35%), Positives = 78/163 (47%), Gaps = 12/163 (7%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANCR 200
F C C G+R GR DEC+ +P C +C+N G++ C C GY+ ++G
Sbjct: 693 FTCECSIGFRGDGRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVA 752
Query: 201 DVDE-----CERDTHTC----QQICSNTEGS-YECSCEDGYEKRGDACVDINECHEEGVC 350
VD+ CE H C + C T GS Y CSC G+ G AC D++EC + C
Sbjct: 753 VVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGFSGDGQACQDVDEC-QPSRC 811
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ 479
C N GSF C C GY+ +G RCV + + RCQ
Sbjct: 812 HPDAFCYNTPGSFTCQCKPGYQ--GDGFRCVPGE--VEKTRCQ 850
Score = 64.1 bits (149), Expect = 3e-10
Identities = 39/114 (34%), Positives = 50/114 (43%), Gaps = 12/114 (10%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGV-------RGRDECAVRPPPCD-----QLCHNTDGSYDCL 155
N G+FRC C GY+ + G R + C CD Q + SY C
Sbjct: 729 NHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCS 788
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV 317
C G+ DG C+DVDEC+ C NT GS+ C C+ GY+ G CV
Sbjct: 789 CLPGFS--GDGQACQDVDECQPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCV 840
Score = 40.7 bits (91), Expect = 0.003
Identities = 23/58 (39%), Positives = 29/58 (50%), Gaps = 3/58 (5%)
Frame = +3
Query: 387 FRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAP--CRNYAGGYRCDCPVGTVRSPSG 551
F C C G+R D G C D DEC+ Q C + C N+ G +RC+C G S G
Sbjct: 693 FTCECSIGFRGD--GRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEG 748
>AC005327-1|AAC27673.1| 287|Homo sapiens CD97_HUMAN, partial CDS
protein.
Length = 287
Score = 98.3 bits (234), Expect = 2e-20
Identities = 64/196 (32%), Positives = 91/196 (46%), Gaps = 25/196 (12%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRD--ECA-VRPPPCDQL--CHNTDGSYDCLCRTGYE--- 173
+ + C C PG+ + D ECA + C + C NT+GSYDC+C GYE
Sbjct: 37 VNATACRCNPGFSSFSEIITTPDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 96
Query: 174 -----LDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACVDINEC 332
+E C+DVDEC+++ C+ C NT GSY C C G++ D+NEC
Sbjct: 97 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK-------DVNEC 149
Query: 333 HE-EGVCPSPGRCVNLLGSFRCVCPRGYR------LDAEGARCVDRDECAQ-TGRCQAP- 485
+ C S C+N +GS++C C G++ C D DEC+ +C +
Sbjct: 150 TSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSST 209
Query: 486 -CRNYAGGYRCDCPVG 530
C N G Y C C G
Sbjct: 210 VCFNTVGSYSCRCRPG 225
Score = 79.0 bits (186), Expect = 1e-14
Identities = 51/158 (32%), Positives = 67/158 (42%), Gaps = 23/158 (14%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG----------RGVRGRDECAVRPPPCDQ--LCHNTDGSYDCL 155
NT GS+ CVC PGY P + DEC P C C NT GSY C
Sbjct: 79 NTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQ 138
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYE--------KRG 305
C G+ +DV+EC + C C N GSY+C C G++
Sbjct: 139 CLPGF---------KDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNN 189
Query: 306 DACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYR 416
C D++EC + C S C N +GS+ C C G++
Sbjct: 190 TVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 227
Score = 77.4 bits (182), Expect = 3e-14
Identities = 40/106 (37%), Positives = 52/106 (49%), Gaps = 8/106 (7%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYEL---D 179
VNT+GS+ C C PG++ G++ C C N GSY C CR G++
Sbjct: 129 VNTLGSYTCQCLPGFKDVNECTSGQNPC-----HSSTHCLNNVGSYQCRCRPGWQPIPGS 183
Query: 180 EDGAN---CRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKR 302
+G N C DVDEC H C +C NT GSY C C G++ R
Sbjct: 184 PNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPR 229
>X94630-1|CAA64333.1| 835|Homo sapiens seven-span transmembrane
protein protein.
Length = 835
Score = 97.9 bits (233), Expect = 2e-20
Identities = 56/159 (35%), Positives = 78/159 (49%), Gaps = 23/159 (14%)
Frame = +3
Query: 123 CHNTDGSYDCLCRTGYE--------LDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYE 272
C NT+GSYDC+C GYE +E C+DVDEC+++ C+ C NT GSY
Sbjct: 82 CWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYT 141
Query: 273 CSCEDGYE---KRGDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYR------LD 422
C C G++ + C D+NEC + C S C+N +GS++C C G++
Sbjct: 142 CQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNG 201
Query: 423 AEGARCVDRDECAQ-TGRCQAP--CRNYAGGYRCDCPVG 530
C D DEC+ +C + C N G Y C C G
Sbjct: 202 PNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPG 240
Score = 90.6 bits (215), Expect = 3e-18
Identities = 54/159 (33%), Positives = 71/159 (44%), Gaps = 24/159 (15%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG----------RGVRGRDECAVRPPPCDQ--LCHNTDGSYDCL 155
NT GS+ CVC PGY P + DEC P C C NT GSY C
Sbjct: 84 NTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQ 143
Query: 156 CRTGYE-LDEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYE--------KR 302
C G++ + ED C DV+EC + C C N GSY+C C G++
Sbjct: 144 CLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPN 203
Query: 303 GDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYR 416
C D++EC + C S C N +GS+ C C G++
Sbjct: 204 NTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 242
Score = 77.4 bits (182), Expect = 3e-14
Identities = 44/111 (39%), Positives = 55/111 (49%), Gaps = 13/111 (11%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGV-RGRDECAVRPPPCDQLCH--NTDGSYDCLCRTGYE 173
VNT+GS+ C C PG++ P V +EC PC H N GSY C CR G++
Sbjct: 134 VNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ 193
Query: 174 L---DEDGAN---CRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKR 302
+G N C DVDEC H C +C NT GSY C C G++ R
Sbjct: 194 PIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPR 244
Score = 49.2 bits (112), Expect = 9e-06
Identities = 40/128 (31%), Positives = 51/128 (39%), Gaps = 24/128 (18%)
Frame = +3
Query: 219 RDTHTCQQIC---SNTEGSYECSCEDGYEKRGD-------ACVDINECHEEGV--CPSPG 362
+D+ C + C S+ + C C G+ + C DINEC C
Sbjct: 21 QDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFS 80
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGAR---------CVDRDECAQTGR-CQA--PCRNYAGG 506
C N GS+ CVC GY GA+ C D DEC Q R C++ C N G
Sbjct: 81 DCWNTEGSYDCVCSPGYE-PVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGS 139
Query: 507 YRCDCPVG 530
Y C C G
Sbjct: 140 YTCQCLPG 147
>U76764-1|AAB36682.1| 835|Homo sapiens CD97 protein.
Length = 835
Score = 97.9 bits (233), Expect = 2e-20
Identities = 56/159 (35%), Positives = 78/159 (49%), Gaps = 23/159 (14%)
Frame = +3
Query: 123 CHNTDGSYDCLCRTGYE--------LDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYE 272
C NT+GSYDC+C GYE +E C+DVDEC+++ C+ C NT GSY
Sbjct: 82 CWNTEGSYDCVCSPGYEPVSGTKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYT 141
Query: 273 CSCEDGYE---KRGDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYR------LD 422
C C G++ + C D+NEC + C S C+N +GS++C C G++
Sbjct: 142 CQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNG 201
Query: 423 AEGARCVDRDECAQ-TGRCQAP--CRNYAGGYRCDCPVG 530
C D DEC+ +C + C N G Y C C G
Sbjct: 202 PNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPG 240
Score = 90.6 bits (215), Expect = 3e-18
Identities = 54/159 (33%), Positives = 71/159 (44%), Gaps = 24/159 (15%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG----------RGVRGRDECAVRPPPCDQ--LCHNTDGSYDCL 155
NT GS+ CVC PGY P + DEC P C C NT GSY C
Sbjct: 84 NTEGSYDCVCSPGYEPVSGTKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQ 143
Query: 156 CRTGYE-LDEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYE--------KR 302
C G++ + ED C DV+EC + C C N GSY+C C G++
Sbjct: 144 CLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPN 203
Query: 303 GDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYR 416
C D++EC + C S C N +GS+ C C G++
Sbjct: 204 NTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 242
Score = 77.4 bits (182), Expect = 3e-14
Identities = 44/111 (39%), Positives = 55/111 (49%), Gaps = 13/111 (11%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGV-RGRDECAVRPPPCDQLCH--NTDGSYDCLCRTGYE 173
VNT+GS+ C C PG++ P V +EC PC H N GSY C CR G++
Sbjct: 134 VNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ 193
Query: 174 L---DEDGAN---CRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKR 302
+G N C DVDEC H C +C NT GSY C C G++ R
Sbjct: 194 PIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPR 244
Score = 47.6 bits (108), Expect = 3e-05
Identities = 39/128 (30%), Positives = 52/128 (40%), Gaps = 24/128 (18%)
Frame = +3
Query: 219 RDTHTCQQIC---SNTEGSYECSCEDGYEKRGD-------ACVDINECHEEGV--CPSPG 362
+D+ C + C S+ + C C G+ + C DINEC C
Sbjct: 21 QDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFS 80
Query: 363 RCVNLLGSFRCVCPRGY---------RLDAEGARCVDRDECAQTGR-CQA--PCRNYAGG 506
C N GS+ CVC GY + ++E C D DEC Q R C++ C N G
Sbjct: 81 DCWNTEGSYDCVCSPGYEPVSGTKTFKNESENT-CQDVDECQQNPRLCKSYGTCVNTLGS 139
Query: 507 YRCDCPVG 530
Y C C G
Sbjct: 140 YTCQCLPG 147
>BC127005-1|AAI27006.1| 823|Homo sapiens egf-like module
containing, mucin-like, hormone receptor-like 2 protein.
Length = 823
Score = 97.9 bits (233), Expect = 2e-20
Identities = 56/159 (35%), Positives = 78/159 (49%), Gaps = 23/159 (14%)
Frame = +3
Query: 123 CHNTDGSYDCLCRTGYE--------LDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYE 272
C NT+GSYDC+C GYE +E C+DVDEC+++ C+ C NT GSY
Sbjct: 85 CWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYT 144
Query: 273 CSCEDGYE---KRGDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYR------LD 422
C C G++ + C D+NEC + C S C+N +GS++C C G++
Sbjct: 145 CQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNG 204
Query: 423 AEGARCVDRDECAQ-TGRCQAP--CRNYAGGYRCDCPVG 530
C D DEC+ +C + C N G Y C C G
Sbjct: 205 PNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPG 243
Score = 90.6 bits (215), Expect = 3e-18
Identities = 54/159 (33%), Positives = 71/159 (44%), Gaps = 24/159 (15%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG----------RGVRGRDECAVRPPPCDQ--LCHNTDGSYDCL 155
NT GS+ CVC PGY P + DEC P C C NT GSY C
Sbjct: 87 NTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQ 146
Query: 156 CRTGYE-LDEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYE--------KR 302
C G++ + ED C DV+EC + C C N GSY+C C G++
Sbjct: 147 CLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPN 206
Query: 303 GDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYR 416
C D++EC + C S C N +GS+ C C G++
Sbjct: 207 NTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 245
Score = 77.4 bits (182), Expect = 3e-14
Identities = 44/111 (39%), Positives = 55/111 (49%), Gaps = 13/111 (11%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGV-RGRDECAVRPPPCDQLCH--NTDGSYDCLCRTGYE 173
VNT+GS+ C C PG++ P V +EC PC H N GSY C CR G++
Sbjct: 137 VNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ 196
Query: 174 L---DEDGAN---CRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKR 302
+G N C DVDEC H C +C NT GSY C C G++ R
Sbjct: 197 PIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPR 247
Score = 49.2 bits (112), Expect = 9e-06
Identities = 40/128 (31%), Positives = 52/128 (40%), Gaps = 24/128 (18%)
Frame = +3
Query: 219 RDTHTCQQIC---SNTEGSYECSCEDGYEKRGD-------ACVDINECH--EEGVCPSPG 362
+D+ C + C S+ + C C G+ + C DINEC + C
Sbjct: 24 QDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFS 83
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGAR---------CVDRDECAQTGR-CQA--PCRNYAGG 506
C N GS+ CVC GY GA+ C D DEC Q R C++ C N G
Sbjct: 84 DCWNTEGSYDCVCSPGYE-PVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGS 142
Query: 507 YRCDCPVG 530
Y C C G
Sbjct: 143 YTCQCLPG 150
>BC127004-1|AAI27005.1| 823|Homo sapiens egf-like module
containing, mucin-like, hormone receptor-like 2 protein.
Length = 823
Score = 97.9 bits (233), Expect = 2e-20
Identities = 56/159 (35%), Positives = 78/159 (49%), Gaps = 23/159 (14%)
Frame = +3
Query: 123 CHNTDGSYDCLCRTGYE--------LDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYE 272
C NT+GSYDC+C GYE +E C+DVDEC+++ C+ C NT GSY
Sbjct: 85 CWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYT 144
Query: 273 CSCEDGYE---KRGDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYR------LD 422
C C G++ + C D+NEC + C S C+N +GS++C C G++
Sbjct: 145 CQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNG 204
Query: 423 AEGARCVDRDECAQ-TGRCQAP--CRNYAGGYRCDCPVG 530
C D DEC+ +C + C N G Y C C G
Sbjct: 205 PNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPG 243
Score = 90.6 bits (215), Expect = 3e-18
Identities = 54/159 (33%), Positives = 71/159 (44%), Gaps = 24/159 (15%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG----------RGVRGRDECAVRPPPCDQ--LCHNTDGSYDCL 155
NT GS+ CVC PGY P + DEC P C C NT GSY C
Sbjct: 87 NTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQ 146
Query: 156 CRTGYE-LDEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYE--------KR 302
C G++ + ED C DV+EC + C C N GSY+C C G++
Sbjct: 147 CLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPN 206
Query: 303 GDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYR 416
C D++EC + C S C N +GS+ C C G++
Sbjct: 207 NTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 245
Score = 77.4 bits (182), Expect = 3e-14
Identities = 44/111 (39%), Positives = 55/111 (49%), Gaps = 13/111 (11%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGV-RGRDECAVRPPPCDQLCH--NTDGSYDCLCRTGYE 173
VNT+GS+ C C PG++ P V +EC PC H N GSY C CR G++
Sbjct: 137 VNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ 196
Query: 174 L---DEDGAN---CRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKR 302
+G N C DVDEC H C +C NT GSY C C G++ R
Sbjct: 197 PIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPR 247
Score = 49.2 bits (112), Expect = 9e-06
Identities = 40/128 (31%), Positives = 52/128 (40%), Gaps = 24/128 (18%)
Frame = +3
Query: 219 RDTHTCQQIC---SNTEGSYECSCEDGYEKRGD-------ACVDINECH--EEGVCPSPG 362
+D+ C + C S+ + C C G+ + C DINEC + C
Sbjct: 24 QDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFS 83
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGAR---------CVDRDECAQTGR-CQA--PCRNYAGG 506
C N GS+ CVC GY GA+ C D DEC Q R C++ C N G
Sbjct: 84 DCWNTEGSYDCVCSPGYE-PVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGS 142
Query: 507 YRCDCPVG 530
Y C C G
Sbjct: 143 YTCQCLPG 150
>AB065966-1|BAC06178.1| 837|Homo sapiens seven transmembrane helix
receptor protein.
Length = 837
Score = 97.9 bits (233), Expect = 2e-20
Identities = 56/159 (35%), Positives = 78/159 (49%), Gaps = 23/159 (14%)
Frame = +3
Query: 123 CHNTDGSYDCLCRTGYE--------LDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYE 272
C NT+GSYDC+C GYE +E C+DVDEC+++ C+ C NT GSY
Sbjct: 84 CWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYT 143
Query: 273 CSCEDGYE---KRGDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYR------LD 422
C C G++ + C D+NEC + C S C+N +GS++C C G++
Sbjct: 144 CQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNG 203
Query: 423 AEGARCVDRDECAQ-TGRCQAP--CRNYAGGYRCDCPVG 530
C D DEC+ +C + C N G Y C C G
Sbjct: 204 PNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPG 242
Score = 90.6 bits (215), Expect = 3e-18
Identities = 54/159 (33%), Positives = 71/159 (44%), Gaps = 24/159 (15%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG----------RGVRGRDECAVRPPPCDQ--LCHNTDGSYDCL 155
NT GS+ CVC PGY P + DEC P C C NT GSY C
Sbjct: 86 NTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQ 145
Query: 156 CRTGYE-LDEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYE--------KR 302
C G++ + ED C DV+EC + C C N GSY+C C G++
Sbjct: 146 CLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPN 205
Query: 303 GDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYR 416
C D++EC + C S C N +GS+ C C G++
Sbjct: 206 NTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 244
Score = 77.4 bits (182), Expect = 3e-14
Identities = 44/111 (39%), Positives = 55/111 (49%), Gaps = 13/111 (11%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGV-RGRDECAVRPPPCDQLCH--NTDGSYDCLCRTGYE 173
VNT+GS+ C C PG++ P V +EC PC H N GSY C CR G++
Sbjct: 136 VNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ 195
Query: 174 L---DEDGAN---CRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKR 302
+G N C DVDEC H C +C NT GSY C C G++ R
Sbjct: 196 PIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPR 246
Score = 49.2 bits (112), Expect = 9e-06
Identities = 40/128 (31%), Positives = 51/128 (39%), Gaps = 24/128 (18%)
Frame = +3
Query: 219 RDTHTCQQIC---SNTEGSYECSCEDGYEKRGD-------ACVDINECHEEGV--CPSPG 362
+D+ C + C S+ + C C G+ + C DINEC C
Sbjct: 23 QDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFS 82
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGAR---------CVDRDECAQTGR-CQA--PCRNYAGG 506
C N GS+ CVC GY GA+ C D DEC Q R C++ C N G
Sbjct: 83 DCWNTEGSYDCVCSPGYE-PVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGS 141
Query: 507 YRCDCPVG 530
Y C C G
Sbjct: 142 YTCQCLPG 149
>Y13341-1|CAA73785.1| 310|Homo sapiens matrilin-3 precursor
protein.
Length = 310
Score = 97.1 bits (231), Expect = 4e-20
Identities = 56/156 (35%), Positives = 72/156 (46%), Gaps = 7/156 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQLC-HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSN-T 257
D C + C +C + +G + C C GY L+ D C +D C +TH C+ IC N
Sbjct: 90 DPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDR 149
Query: 258 EGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVN-LLGSFRCVCPRGYRLDAE 428
GSY C C +GY D C ++C G CVN GS C C GY L+A+
Sbjct: 150 SGSYHCECYEGYTLNEDRKTCSAQDKC-ALGTHGCQHICVNDRTGSHHCECYEGYTLNAD 208
Query: 429 GARCVDRDECAQTGR-CQAPC-RNYAGGYRCDCPVG 530
C RD+CA CQ C + A Y CDC G
Sbjct: 209 KKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPG 244
Score = 86.2 bits (204), Expect = 7e-17
Identities = 53/167 (31%), Positives = 71/167 (42%), Gaps = 11/167 (6%)
Frame = +3
Query: 21 GSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNT-DGSYDCLCRTGYELDEDGA 191
G C C GY + D CA+ C+ +C N GSY C C GY L+ED
Sbjct: 109 GKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDRSGSYHCECYEGYTLNEDRK 168
Query: 192 NCRDVDECERDTHTCQQICSNTE-GSYECSCEDGYEKRGD--ACVDINEC----HE-EGV 347
C D+C TH CQ IC N GS+ C C +GY D C ++C H + +
Sbjct: 169 TCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHI 228
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPC 488
C S G S+ C C GY L+ + C +E + + C
Sbjct: 229 CVSDG-----AASYHCDCYPGYTLNEDKKTCSATEEARRLVSTEDAC 270
Score = 68.1 bits (159), Expect = 2e-11
Identities = 40/115 (34%), Positives = 53/115 (46%), Gaps = 6/115 (5%)
Frame = +3
Query: 204 VDECERDTHTCQQIC-SNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVN 374
+D C TH CQ +C S+ EG + C C GY D C ++ C CVN
Sbjct: 89 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRC-ALNTHGCEHICVN 147
Query: 375 -LLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRN-YAGGYRCDCPVG 530
GS+ C C GY L+ + C +D+CA T CQ C N G + C+C G
Sbjct: 148 DRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEG 202
>D86425-1|BAA13087.1| 1376|Homo sapiens osteonidogen protein.
Length = 1376
Score = 97.1 bits (231), Expect = 4e-20
Identities = 58/172 (33%), Positives = 78/172 (45%), Gaps = 11/172 (6%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANC- 197
+ C C GY+ GR +ECA C + +C N GSY C CR+GYE +D C
Sbjct: 785 YTCECASGYQGDGRNCVDENECATGFHRCGPNSVCINLPGSYRCECRSGYEFADDRHTCI 844
Query: 198 ---RDVDECERDTHTC----QQICSNTEGS-YECSCEDGYEKRGDACVDINECHEEGVCP 353
+ CE +HTC Q C + GS + C+C GY G C D++EC E C
Sbjct: 845 LITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDGHQCTDVDEC-SENRCH 903
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGY 509
C N GSF C C GY +G +C+ D + C+ R+ Y
Sbjct: 904 PAATCYNTPGSFSCRCQPGYY--GDGFQCIP-DSTSSLTPCEQQQRHAQAQY 952
Score = 92.7 bits (220), Expect = 8e-19
Identities = 59/151 (39%), Positives = 71/151 (47%), Gaps = 15/151 (9%)
Frame = +3
Query: 123 CHNTDG-SYDCLCRTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGY 293
CH G Y C C +GY+ DG NC D +EC H C +C N GSY C C GY
Sbjct: 777 CHPGTGVDYTCECASGYQ--GDGRNCVDENECATGFHRCGPNSVCINLPGSYRCECRSGY 834
Query: 294 EKRGD--ACVDI----NECHE-EGVCPSPG--RCVNLLGS-FRCVCPRGYRLDAEGARCV 443
E D C+ I N C + C G RCV+ GS F C C GY +G +C
Sbjct: 835 EFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYA--GDGHQCT 892
Query: 444 DRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
D DEC++ RC A C N G + C C G
Sbjct: 893 DVDECSE-NRCHPAATCYNTPGSFSCRCQPG 922
Score = 62.1 bits (144), Expect = 1e-09
Identities = 40/118 (33%), Positives = 51/118 (43%), Gaps = 15/118 (12%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECA-VRPP--PCDQ---LC---------HNTDGS 143
+N GS+RC C GY A R C + PP PC+ C H+ +
Sbjct: 820 INLPGSYRCECRSGYEFAD----DRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGST 875
Query: 144 YDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV 317
+ C C GY DG C DVDEC + C NT GS+ C C+ GY G C+
Sbjct: 876 FSCACLPGYA--GDGHQCTDVDECSENRCHPAATCYNTPGSFSCRCQPGYYGDGFQCI 931
>BC139907-1|AAI39908.1| 486|Homo sapiens matrilin 3 protein.
Length = 486
Score = 97.1 bits (231), Expect = 4e-20
Identities = 56/156 (35%), Positives = 72/156 (46%), Gaps = 7/156 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQLC-HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSN-T 257
D C + C +C + +G + C C GY L+ D C +D C +TH C+ IC N
Sbjct: 266 DPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDR 325
Query: 258 EGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVN-LLGSFRCVCPRGYRLDAE 428
GSY C C +GY D C ++C G CVN GS C C GY L+A+
Sbjct: 326 SGSYHCECYEGYTLNEDRKTCSAQDKC-ALGTHGCQHICVNDRTGSHHCECYEGYTLNAD 384
Query: 429 GARCVDRDECAQTGR-CQAPC-RNYAGGYRCDCPVG 530
C RD+CA CQ C + A Y CDC G
Sbjct: 385 KKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPG 420
Score = 86.2 bits (204), Expect = 7e-17
Identities = 53/167 (31%), Positives = 71/167 (42%), Gaps = 11/167 (6%)
Frame = +3
Query: 21 GSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNT-DGSYDCLCRTGYELDEDGA 191
G C C GY + D CA+ C+ +C N GSY C C GY L+ED
Sbjct: 285 GKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDRSGSYHCECYEGYTLNEDRK 344
Query: 192 NCRDVDECERDTHTCQQICSNTE-GSYECSCEDGYEKRGD--ACVDINEC----HE-EGV 347
C D+C TH CQ IC N GS+ C C +GY D C ++C H + +
Sbjct: 345 TCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHI 404
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPC 488
C S G S+ C C GY L+ + C +E + + C
Sbjct: 405 CVSDG-----AASYHCDCYPGYTLNEDKKTCSATEEARRLVSTEDAC 446
Score = 68.1 bits (159), Expect = 2e-11
Identities = 40/115 (34%), Positives = 53/115 (46%), Gaps = 6/115 (5%)
Frame = +3
Query: 204 VDECERDTHTCQQIC-SNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVN 374
+D C TH CQ +C S+ EG + C C GY D C ++ C CVN
Sbjct: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRC-ALNTHGCEHICVN 323
Query: 375 -LLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRN-YAGGYRCDCPVG 530
GS+ C C GY L+ + C +D+CA T CQ C N G + C+C G
Sbjct: 324 DRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEG 378
>AJ224741-1|CAA12110.1| 486|Homo sapiens matrilin-3 protein.
Length = 486
Score = 97.1 bits (231), Expect = 4e-20
Identities = 56/156 (35%), Positives = 72/156 (46%), Gaps = 7/156 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQLC-HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSN-T 257
D C + C +C + +G + C C GY L+ D C +D C +TH C+ IC N
Sbjct: 266 DPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDR 325
Query: 258 EGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVN-LLGSFRCVCPRGYRLDAE 428
GSY C C +GY D C ++C G CVN GS C C GY L+A+
Sbjct: 326 SGSYHCECYEGYTLNEDRKTCSAQDKC-ALGTHGCQHICVNDRTGSHHCECYEGYTLNAD 384
Query: 429 GARCVDRDECAQTGR-CQAPC-RNYAGGYRCDCPVG 530
C RD+CA CQ C + A Y CDC G
Sbjct: 385 KKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPG 420
Score = 86.2 bits (204), Expect = 7e-17
Identities = 53/167 (31%), Positives = 71/167 (42%), Gaps = 11/167 (6%)
Frame = +3
Query: 21 GSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNT-DGSYDCLCRTGYELDEDGA 191
G C C GY + D CA+ C+ +C N GSY C C GY L+ED
Sbjct: 285 GKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDRSGSYHCECYEGYTLNEDRK 344
Query: 192 NCRDVDECERDTHTCQQICSNTE-GSYECSCEDGYEKRGD--ACVDINEC----HE-EGV 347
C D+C TH CQ IC N GS+ C C +GY D C ++C H + +
Sbjct: 345 TCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHI 404
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPC 488
C S G S+ C C GY L+ + C +E + + C
Sbjct: 405 CVSDG-----AASYHCDCYPGYTLNEDKKTCSATEEARRLVSTEDAC 446
Score = 68.1 bits (159), Expect = 2e-11
Identities = 40/115 (34%), Positives = 53/115 (46%), Gaps = 6/115 (5%)
Frame = +3
Query: 204 VDECERDTHTCQQIC-SNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVN 374
+D C TH CQ +C S+ EG + C C GY D C ++ C CVN
Sbjct: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRC-ALNTHGCEHICVN 323
Query: 375 -LLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRN-YAGGYRCDCPVG 530
GS+ C C GY L+ + C +D+CA T CQ C N G + C+C G
Sbjct: 324 DRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEG 378
>AJ223500-1|CAA11418.1| 1375|Homo sapiens nidogen-2 protein.
Length = 1375
Score = 97.1 bits (231), Expect = 4e-20
Identities = 58/172 (33%), Positives = 78/172 (45%), Gaps = 11/172 (6%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANC- 197
+ C C GY+ GR +ECA C + +C N GSY C CR+GYE +D C
Sbjct: 784 YTCECASGYQGDGRNCVDENECATGFHRCGPNSVCINLPGSYRCECRSGYEFADDRHTCI 843
Query: 198 ---RDVDECERDTHTC----QQICSNTEGS-YECSCEDGYEKRGDACVDINECHEEGVCP 353
+ CE +HTC Q C + GS + C+C GY G C D++EC E C
Sbjct: 844 LITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDGHQCTDVDEC-SENRCH 902
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGY 509
C N GSF C C GY +G +C+ D + C+ R+ Y
Sbjct: 903 PAATCYNTPGSFSCRCQPGYY--GDGFQCIP-DSTSSLTPCEQQQRHAQAQY 951
Score = 92.7 bits (220), Expect = 8e-19
Identities = 59/151 (39%), Positives = 71/151 (47%), Gaps = 15/151 (9%)
Frame = +3
Query: 123 CHNTDG-SYDCLCRTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGY 293
CH G Y C C +GY+ DG NC D +EC H C +C N GSY C C GY
Sbjct: 776 CHPGTGVDYTCECASGYQ--GDGRNCVDENECATGFHRCGPNSVCINLPGSYRCECRSGY 833
Query: 294 EKRGD--ACVDI----NECHE-EGVCPSPG--RCVNLLGS-FRCVCPRGYRLDAEGARCV 443
E D C+ I N C + C G RCV+ GS F C C GY +G +C
Sbjct: 834 EFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYA--GDGHQCT 891
Query: 444 DRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
D DEC++ RC A C N G + C C G
Sbjct: 892 DVDECSE-NRCHPAATCYNTPGSFSCRCQPG 921
Score = 62.1 bits (144), Expect = 1e-09
Identities = 40/118 (33%), Positives = 51/118 (43%), Gaps = 15/118 (12%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECA-VRPP--PCDQ---LC---------HNTDGS 143
+N GS+RC C GY A R C + PP PC+ C H+ +
Sbjct: 819 INLPGSYRCECRSGYEFAD----DRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGST 874
Query: 144 YDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV 317
+ C C GY DG C DVDEC + C NT GS+ C C+ GY G C+
Sbjct: 875 FSCACLPGYA--GDGHQCTDVDECSENRCHPAATCYNTPGSFSCRCQPGYYGDGFQCI 930
>AJ001047-1|CAA04501.1| 303|Homo sapiens Matrilin-3 protein.
Length = 303
Score = 97.1 bits (231), Expect = 4e-20
Identities = 56/156 (35%), Positives = 72/156 (46%), Gaps = 7/156 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQLC-HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSN-T 257
D C + C +C + +G + C C GY L+ D C +D C +TH C+ IC N
Sbjct: 83 DPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDR 142
Query: 258 EGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVN-LLGSFRCVCPRGYRLDAE 428
GSY C C +GY D C ++C G CVN GS C C GY L+A+
Sbjct: 143 SGSYHCECYEGYTLNEDRKTCSAQDKC-ALGTHGCQHICVNDRTGSHHCECYEGYTLNAD 201
Query: 429 GARCVDRDECAQTGR-CQAPC-RNYAGGYRCDCPVG 530
C RD+CA CQ C + A Y CDC G
Sbjct: 202 KKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPG 237
Score = 86.2 bits (204), Expect = 7e-17
Identities = 53/167 (31%), Positives = 71/167 (42%), Gaps = 11/167 (6%)
Frame = +3
Query: 21 GSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNT-DGSYDCLCRTGYELDEDGA 191
G C C GY + D CA+ C+ +C N GSY C C GY L+ED
Sbjct: 102 GKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDRSGSYHCECYEGYTLNEDRK 161
Query: 192 NCRDVDECERDTHTCQQICSNTE-GSYECSCEDGYEKRGD--ACVDINEC----HE-EGV 347
C D+C TH CQ IC N GS+ C C +GY D C ++C H + +
Sbjct: 162 TCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHI 221
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPC 488
C S G S+ C C GY L+ + C +E + + C
Sbjct: 222 CVSDG-----AASYHCDCYPGYTLNEDKKTCSATEEARRLVSTEDAC 263
Score = 68.1 bits (159), Expect = 2e-11
Identities = 40/115 (34%), Positives = 53/115 (46%), Gaps = 6/115 (5%)
Frame = +3
Query: 204 VDECERDTHTCQQIC-SNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVN 374
+D C TH CQ +C S+ EG + C C GY D C ++ C CVN
Sbjct: 82 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRC-ALNTHGCEHICVN 140
Query: 375 -LLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRN-YAGGYRCDCPVG 530
GS+ C C GY L+ + C +D+CA T CQ C N G + C+C G
Sbjct: 141 DRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEG 195
>AC079145-2|AAX88937.1| 486|Homo sapiens unknown protein.
Length = 486
Score = 97.1 bits (231), Expect = 4e-20
Identities = 56/156 (35%), Positives = 72/156 (46%), Gaps = 7/156 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQLC-HNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSN-T 257
D C + C +C + +G + C C GY L+ D C +D C +TH C+ IC N
Sbjct: 266 DPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDR 325
Query: 258 EGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVN-LLGSFRCVCPRGYRLDAE 428
GSY C C +GY D C ++C G CVN GS C C GY L+A+
Sbjct: 326 SGSYHCECYEGYTLNEDRKTCSAQDKC-ALGTHGCQHICVNDRTGSHHCECYEGYTLNAD 384
Query: 429 GARCVDRDECAQTGR-CQAPC-RNYAGGYRCDCPVG 530
C RD+CA CQ C + A Y CDC G
Sbjct: 385 KKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPG 420
Score = 86.2 bits (204), Expect = 7e-17
Identities = 53/167 (31%), Positives = 71/167 (42%), Gaps = 11/167 (6%)
Frame = +3
Query: 21 GSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNT-DGSYDCLCRTGYELDEDGA 191
G C C GY + D CA+ C+ +C N GSY C C GY L+ED
Sbjct: 285 GKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDRSGSYHCECYEGYTLNEDRK 344
Query: 192 NCRDVDECERDTHTCQQICSNTE-GSYECSCEDGYEKRGD--ACVDINEC----HE-EGV 347
C D+C TH CQ IC N GS+ C C +GY D C ++C H + +
Sbjct: 345 TCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHI 404
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPC 488
C S G S+ C C GY L+ + C +E + + C
Sbjct: 405 CVSDG-----AASYHCDCYPGYTLNEDKKTCSATEEARRLVSTEDAC 446
Score = 68.1 bits (159), Expect = 2e-11
Identities = 40/115 (34%), Positives = 53/115 (46%), Gaps = 6/115 (5%)
Frame = +3
Query: 204 VDECERDTHTCQQIC-SNTEGSYECSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVN 374
+D C TH CQ +C S+ EG + C C GY D C ++ C CVN
Sbjct: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRC-ALNTHGCEHICVN 323
Query: 375 -LLGSFRCVCPRGYRLDAEGARCVDRDECA-QTGRCQAPCRN-YAGGYRCDCPVG 530
GS+ C C GY L+ + C +D+CA T CQ C N G + C+C G
Sbjct: 324 DRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEG 378
>AB009799-1|BAA24112.1| 1376|Homo sapiens osteonidogen protein.
Length = 1376
Score = 97.1 bits (231), Expect = 4e-20
Identities = 58/172 (33%), Positives = 78/172 (45%), Gaps = 11/172 (6%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANC- 197
+ C C GY+ GR +ECA C + +C N GSY C CR+GYE +D C
Sbjct: 785 YTCECASGYQGDGRNCVDENECATGFHRCGPNSVCINLPGSYRCECRSGYEFADDRHTCI 844
Query: 198 ---RDVDECERDTHTC----QQICSNTEGS-YECSCEDGYEKRGDACVDINECHEEGVCP 353
+ CE +HTC Q C + GS + C+C GY G C D++EC E C
Sbjct: 845 LITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDGHQCTDVDEC-SENRCH 903
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGY 509
C N GSF C C GY +G +C+ D + C+ R+ Y
Sbjct: 904 PAATCYNTPGSFSCRCQPGYY--GDGFQCIP-DSTSSLTPCEQQQRHAQAQY 952
Score = 92.7 bits (220), Expect = 8e-19
Identities = 59/151 (39%), Positives = 71/151 (47%), Gaps = 15/151 (9%)
Frame = +3
Query: 123 CHNTDG-SYDCLCRTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGY 293
CH G Y C C +GY+ DG NC D +EC H C +C N GSY C C GY
Sbjct: 777 CHPGTGVDYTCECASGYQ--GDGRNCVDENECATGFHRCGPNSVCINLPGSYRCECRSGY 834
Query: 294 EKRGD--ACVDI----NECHE-EGVCPSPG--RCVNLLGS-FRCVCPRGYRLDAEGARCV 443
E D C+ I N C + C G RCV+ GS F C C GY +G +C
Sbjct: 835 EFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYA--GDGHQCT 892
Query: 444 DRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
D DEC++ RC A C N G + C C G
Sbjct: 893 DVDECSE-NRCHPAATCYNTPGSFSCRCQPG 922
Score = 62.1 bits (144), Expect = 1e-09
Identities = 40/118 (33%), Positives = 51/118 (43%), Gaps = 15/118 (12%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECA-VRPP--PCDQ---LC---------HNTDGS 143
+N GS+RC C GY A R C + PP PC+ C H+ +
Sbjct: 820 INLPGSYRCECRSGYEFAD----DRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGST 875
Query: 144 YDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV 317
+ C C GY DG C DVDEC + C NT GS+ C C+ GY G C+
Sbjct: 876 FSCACLPGYA--GDGHQCTDVDECSENRCHPAATCYNTPGSFSCRCQPGYYGDGFQCI 931
>BC035608-1|AAH35608.1| 969|Homo sapiens NID2 protein protein.
Length = 969
Score = 94.7 bits (225), Expect = 2e-19
Identities = 57/172 (33%), Positives = 77/172 (44%), Gaps = 11/172 (6%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANC- 197
+ C C GY+ GR +ECA C + +C N GSY C CR+ YE +D C
Sbjct: 378 YTCECASGYQGDGRNCVDENECATGFHRCGPNSVCINLPGSYRCECRSAYEFADDRHTCI 437
Query: 198 ---RDVDECERDTHTC----QQICSNTEGS-YECSCEDGYEKRGDACVDINECHEEGVCP 353
+ CE +HTC Q C + GS + C+C GY G C D++EC E C
Sbjct: 438 LITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDGHQCTDVDEC-SENRCH 496
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGY 509
C N GSF C C GY +G +C+ D + C+ R+ Y
Sbjct: 497 PAATCYNTPGSFSCRCQPGYY--GDGFQCIP-DSTSSLTPCEQQQRHAQAQY 545
Score = 90.2 bits (214), Expect = 4e-18
Identities = 58/151 (38%), Positives = 70/151 (46%), Gaps = 15/151 (9%)
Frame = +3
Query: 123 CHNTDG-SYDCLCRTGYELDEDGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGY 293
CH G Y C C +GY+ DG NC D +EC H C +C N GSY C C Y
Sbjct: 370 CHPGTGVDYTCECASGYQ--GDGRNCVDENECATGFHRCGPNSVCINLPGSYRCECRSAY 427
Query: 294 EKRGD--ACVDI----NECHE-EGVCPSPG--RCVNLLGS-FRCVCPRGYRLDAEGARCV 443
E D C+ I N C + C G RCV+ GS F C C GY +G +C
Sbjct: 428 EFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYA--GDGHQCT 485
Query: 444 DRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
D DEC++ RC A C N G + C C G
Sbjct: 486 DVDECSE-NRCHPAATCYNTPGSFSCRCQPG 515
Score = 59.7 bits (138), Expect = 7e-09
Identities = 39/118 (33%), Positives = 50/118 (42%), Gaps = 15/118 (12%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECA-VRPP--PCDQ---LC---------HNTDGS 143
+N GS+RC C Y A R C + PP PC+ C H+ +
Sbjct: 413 INLPGSYRCECRSAYEFAD----DRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGST 468
Query: 144 YDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV 317
+ C C GY DG C DVDEC + C NT GS+ C C+ GY G C+
Sbjct: 469 FSCACLPGYA--GDGHQCTDVDECSENRCHPAATCYNTPGSFSCRCQPGYYGDGFQCI 524
Score = 53.6 bits (123), Expect = 4e-07
Identities = 37/116 (31%), Positives = 45/116 (38%), Gaps = 4/116 (3%)
Frame = +3
Query: 204 VDECERDTHTCQQICSNTEGS---YECSCEDGYEKRGDACVDINECHEE-GVCPSPGRCV 371
V+ C +H C G+ Y C C GY+ G CVD NEC C C+
Sbjct: 354 VNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRNCVDENECATGFHRCGPNSVCI 413
Query: 372 NLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVR 539
NL GS+RC C Y DR C PC + G + C P G R
Sbjct: 414 NLPGSYRCECRSAYEF------ADDRHTCILITPPANPCED--GSHTC-APAGQAR 460
>D83017-1|BAA11680.1| 810|Homo sapiens nel-related protein protein.
Length = 810
Score = 94.3 bits (224), Expect = 3e-19
Identities = 69/187 (36%), Positives = 88/187 (47%), Gaps = 13/187 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY-RPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELD 179
VN G +RC C PGY R DEC CD+ +C NT + C C+ GY
Sbjct: 452 VNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYV-- 509
Query: 180 EDGANCRDV-DECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGV-C 350
+G CR +E R TC + N +C C G+ G C DI+EC E + C
Sbjct: 510 GNGTICRAFCEEGCRYGGTC--VAPN-----KCVCPSGFT--GSHCEKDIDECSEGIIEC 560
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDA----EGARCVDRDECA-QTGRC--QAPCRNYAGGY 509
+ RCVNL G + C C G+ D G C+D DECA +T C + C N AGG+
Sbjct: 561 HNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGF 620
Query: 510 RCDCPVG 530
C CP G
Sbjct: 621 DCLCPSG 627
Score = 84.6 bits (200), Expect = 2e-16
Identities = 57/157 (36%), Positives = 75/157 (47%), Gaps = 8/157 (5%)
Frame = +3
Query: 84 DECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICS 251
DECA + C + +C N G Y C C GY + D +C + DEC H C + IC+
Sbjct: 436 DECAAKMHYCHANTVCVNLPGLYRCDCVPGY-IRVDDFSCTEHDECGSGQHNCDENAICT 494
Query: 252 NTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEG 431
NT + C+C+ GY G C C EEG C G CV +CVCP G+ G
Sbjct: 495 NTVQGHSCTCKPGYVGNGTICRAF--C-EEG-CRYGGTCV---APNKCVCPSGF----TG 543
Query: 432 ARC-VDRDECAQ-TGRC--QAPCRNYAGGYRCDCPVG 530
+ C D DEC++ C + C N G Y C+C G
Sbjct: 544 SHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSG 580
Score = 82.2 bits (194), Expect = 1e-15
Identities = 51/162 (31%), Positives = 68/162 (41%), Gaps = 7/162 (4%)
Frame = +3
Query: 66 RGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGY-ELDEDGANCRDVDECERDTHTC 236
R RG + CA P C + C N + C C++GY + D A C D+DEC H C
Sbjct: 387 RVCRGHNFCA-EGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYC 445
Query: 237 --QQICSNTEGSYECSCEDGYEKRGD-ACVDINECHE-EGVCPSPGRCVNLLGSFRCVCP 404
+C N G Y C C GY + D +C + +EC + C C N + C C
Sbjct: 446 HANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCK 505
Query: 405 RGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
GY + R + C G C AP +C CP G
Sbjct: 506 PGYVGNGTICRAFCEEGCRYGGTCVAP-------NKCVCPSG 540
Score = 62.1 bits (144), Expect = 1e-09
Identities = 36/109 (33%), Positives = 47/109 (43%), Gaps = 8/109 (7%)
Frame = +3
Query: 6 GVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELD 179
G + +CVC G+ + DEC+ C C N G Y C CR+G+ D
Sbjct: 526 GGTCVAPNKCVCPSGFT-GSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFHDD 584
Query: 180 E----DGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGD 308
G +C D+DEC THTC C N G ++C C G GD
Sbjct: 585 GTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSGPSCSGD 633
Score = 49.2 bits (112), Expect = 9e-06
Identities = 30/80 (37%), Positives = 34/80 (42%), Gaps = 4/80 (5%)
Frame = +3
Query: 312 CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGY-RLDAEGARCVDRDECA-QTGRCQAP 485
C N C E C C N C C GY + + A C D DECA + C A
Sbjct: 389 CRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHAN 448
Query: 486 --CRNYAGGYRCDCPVGTVR 539
C N G YRCDC G +R
Sbjct: 449 TVCVNLPGLYRCDCVPGYIR 468
>BC096102-1|AAH96102.1| 810|Homo sapiens NEL-like 1 (chicken)
protein.
Length = 810
Score = 94.3 bits (224), Expect = 3e-19
Identities = 69/187 (36%), Positives = 88/187 (47%), Gaps = 13/187 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY-RPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELD 179
VN G +RC C PGY R DEC CD+ +C NT + C C+ GY
Sbjct: 452 VNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYV-- 509
Query: 180 EDGANCRDV-DECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGV-C 350
+G CR +E R TC + N +C C G+ G C DI+EC E + C
Sbjct: 510 GNGTICRAFCEEGCRYGGTC--VAPN-----KCVCPSGFT--GSHCEKDIDECSEGIIEC 560
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDA----EGARCVDRDECA-QTGRC--QAPCRNYAGGY 509
+ RCVNL G + C C G+ D G C+D DECA +T C + C N AGG+
Sbjct: 561 HNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGF 620
Query: 510 RCDCPVG 530
C CP G
Sbjct: 621 DCLCPSG 627
Score = 84.6 bits (200), Expect = 2e-16
Identities = 57/157 (36%), Positives = 75/157 (47%), Gaps = 8/157 (5%)
Frame = +3
Query: 84 DECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICS 251
DECA + C + +C N G Y C C GY + D +C + DEC H C + IC+
Sbjct: 436 DECAAKMHYCHANTVCVNLPGLYRCDCVPGY-IRVDDFSCTEHDECGSGQHNCDENAICT 494
Query: 252 NTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEG 431
NT + C+C+ GY G C C EEG C G CV +CVCP G+ G
Sbjct: 495 NTVQGHSCTCKPGYVGNGTICRAF--C-EEG-CRYGGTCV---APNKCVCPSGF----TG 543
Query: 432 ARC-VDRDECAQ-TGRC--QAPCRNYAGGYRCDCPVG 530
+ C D DEC++ C + C N G Y C+C G
Sbjct: 544 SHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSG 580
Score = 82.2 bits (194), Expect = 1e-15
Identities = 51/162 (31%), Positives = 68/162 (41%), Gaps = 7/162 (4%)
Frame = +3
Query: 66 RGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGY-ELDEDGANCRDVDECERDTHTC 236
R RG + CA P C + C N + C C++GY + D A C D+DEC H C
Sbjct: 387 RVCRGHNFCA-EGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYC 445
Query: 237 --QQICSNTEGSYECSCEDGYEKRGD-ACVDINECHE-EGVCPSPGRCVNLLGSFRCVCP 404
+C N G Y C C GY + D +C + +EC + C C N + C C
Sbjct: 446 HANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCK 505
Query: 405 RGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
GY + R + C G C AP +C CP G
Sbjct: 506 PGYVGNGTICRAFCEEGCRYGGTCVAP-------NKCVCPSG 540
Score = 62.1 bits (144), Expect = 1e-09
Identities = 36/109 (33%), Positives = 47/109 (43%), Gaps = 8/109 (7%)
Frame = +3
Query: 6 GVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELD 179
G + +CVC G+ + DEC+ C C N G Y C CR+G+ D
Sbjct: 526 GGTCVAPNKCVCPSGFT-GSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFHDD 584
Query: 180 E----DGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGD 308
G +C D+DEC THTC C N G ++C C G GD
Sbjct: 585 GTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSGPSCSGD 633
Score = 49.2 bits (112), Expect = 9e-06
Identities = 30/80 (37%), Positives = 34/80 (42%), Gaps = 4/80 (5%)
Frame = +3
Query: 312 CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGY-RLDAEGARCVDRDECA-QTGRCQAP 485
C N C E C C N C C GY + + A C D DECA + C A
Sbjct: 389 CRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHAN 448
Query: 486 --CRNYAGGYRCDCPVGTVR 539
C N G YRCDC G +R
Sbjct: 449 TVCVNLPGLYRCDCVPGYIR 468
>BC096101-1|AAH96101.1| 810|Homo sapiens NEL-like 1 (chicken)
protein.
Length = 810
Score = 94.3 bits (224), Expect = 3e-19
Identities = 69/187 (36%), Positives = 88/187 (47%), Gaps = 13/187 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY-RPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELD 179
VN G +RC C PGY R DEC CD+ +C NT + C C+ GY
Sbjct: 452 VNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYV-- 509
Query: 180 EDGANCRDV-DECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGV-C 350
+G CR +E R TC + N +C C G+ G C DI+EC E + C
Sbjct: 510 GNGTICRAFCEEGCRYGGTC--VAPN-----KCVCPSGFT--GSHCEKDIDECSEGIIEC 560
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDA----EGARCVDRDECA-QTGRC--QAPCRNYAGGY 509
+ RCVNL G + C C G+ D G C+D DECA +T C + C N AGG+
Sbjct: 561 HNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGF 620
Query: 510 RCDCPVG 530
C CP G
Sbjct: 621 DCLCPSG 627
Score = 84.6 bits (200), Expect = 2e-16
Identities = 57/157 (36%), Positives = 75/157 (47%), Gaps = 8/157 (5%)
Frame = +3
Query: 84 DECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICS 251
DECA + C + +C N G Y C C GY + D +C + DEC H C + IC+
Sbjct: 436 DECAAKMHYCHANTVCVNLPGLYRCDCVPGY-IRVDDFSCTEHDECGSGQHNCDENAICT 494
Query: 252 NTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEG 431
NT + C+C+ GY G C C EEG C G CV +CVCP G+ G
Sbjct: 495 NTVQGHSCTCKPGYVGNGTICRAF--C-EEG-CRYGGTCV---APNKCVCPSGF----TG 543
Query: 432 ARC-VDRDECAQ-TGRC--QAPCRNYAGGYRCDCPVG 530
+ C D DEC++ C + C N G Y C+C G
Sbjct: 544 SHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSG 580
Score = 82.2 bits (194), Expect = 1e-15
Identities = 51/162 (31%), Positives = 68/162 (41%), Gaps = 7/162 (4%)
Frame = +3
Query: 66 RGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGY-ELDEDGANCRDVDECERDTHTC 236
R RG + CA P C + C N + C C++GY + D A C D+DEC H C
Sbjct: 387 RVCRGHNFCA-EGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYC 445
Query: 237 --QQICSNTEGSYECSCEDGYEKRGD-ACVDINECHE-EGVCPSPGRCVNLLGSFRCVCP 404
+C N G Y C C GY + D +C + +EC + C C N + C C
Sbjct: 446 HANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCK 505
Query: 405 RGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
GY + R + C G C AP +C CP G
Sbjct: 506 PGYVGNGTICRAFCEEGCRYGGTCVAP-------NKCVCPSG 540
Score = 62.1 bits (144), Expect = 1e-09
Identities = 36/109 (33%), Positives = 47/109 (43%), Gaps = 8/109 (7%)
Frame = +3
Query: 6 GVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELD 179
G + +CVC G+ + DEC+ C C N G Y C CR+G+ D
Sbjct: 526 GGTCVAPNKCVCPSGFT-GSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFHDD 584
Query: 180 E----DGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGD 308
G +C D+DEC THTC C N G ++C C G GD
Sbjct: 585 GTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSGPSCSGD 633
Score = 49.2 bits (112), Expect = 9e-06
Identities = 30/80 (37%), Positives = 34/80 (42%), Gaps = 4/80 (5%)
Frame = +3
Query: 312 CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGY-RLDAEGARCVDRDECA-QTGRCQAP 485
C N C E C C N C C GY + + A C D DECA + C A
Sbjct: 389 CRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHAN 448
Query: 486 --CRNYAGGYRCDCPVGTVR 539
C N G YRCDC G +R
Sbjct: 449 TVCVNLPGLYRCDCVPGYIR 468
>BC069674-1|AAH69674.1| 810|Homo sapiens nel-like 1, precursor
protein.
Length = 810
Score = 94.3 bits (224), Expect = 3e-19
Identities = 69/187 (36%), Positives = 88/187 (47%), Gaps = 13/187 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY-RPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELD 179
VN G +RC C PGY R DEC CD+ +C NT + C C+ GY
Sbjct: 452 VNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYV-- 509
Query: 180 EDGANCRDV-DECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGV-C 350
+G CR +E R TC + N +C C G+ G C DI+EC E + C
Sbjct: 510 GNGTICRAFCEEGCRYGGTC--VAPN-----KCVCPSGFT--GSHCEKDIDECSEGIIEC 560
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDA----EGARCVDRDECA-QTGRC--QAPCRNYAGGY 509
+ RCVNL G + C C G+ D G C+D DECA +T C + C N AGG+
Sbjct: 561 HNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGF 620
Query: 510 RCDCPVG 530
C CP G
Sbjct: 621 DCLCPSG 627
Score = 84.6 bits (200), Expect = 2e-16
Identities = 57/157 (36%), Positives = 75/157 (47%), Gaps = 8/157 (5%)
Frame = +3
Query: 84 DECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICS 251
DECA + C + +C N G Y C C GY + D +C + DEC H C + IC+
Sbjct: 436 DECAAKMHYCHANTVCVNLPGLYRCDCVPGY-IRVDDFSCTEHDECGSGQHNCDENAICT 494
Query: 252 NTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEG 431
NT + C+C+ GY G C C EEG C G CV +CVCP G+ G
Sbjct: 495 NTVQGHSCTCKPGYVGNGTICRAF--C-EEG-CRYGGTCV---APNKCVCPSGF----TG 543
Query: 432 ARC-VDRDECAQ-TGRC--QAPCRNYAGGYRCDCPVG 530
+ C D DEC++ C + C N G Y C+C G
Sbjct: 544 SHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSG 580
Score = 82.2 bits (194), Expect = 1e-15
Identities = 51/162 (31%), Positives = 68/162 (41%), Gaps = 7/162 (4%)
Frame = +3
Query: 66 RGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGY-ELDEDGANCRDVDECERDTHTC 236
R RG + CA P C + C N + C C++GY + D A C D+DEC H C
Sbjct: 387 RVCRGHNFCA-EGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYC 445
Query: 237 --QQICSNTEGSYECSCEDGYEKRGD-ACVDINECHE-EGVCPSPGRCVNLLGSFRCVCP 404
+C N G Y C C GY + D +C + +EC + C C N + C C
Sbjct: 446 HANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCK 505
Query: 405 RGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
GY + R + C G C AP +C CP G
Sbjct: 506 PGYVGNGTICRAFCEEGCRYGGTCVAP-------NKCVCPSG 540
Score = 62.1 bits (144), Expect = 1e-09
Identities = 36/109 (33%), Positives = 47/109 (43%), Gaps = 8/109 (7%)
Frame = +3
Query: 6 GVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELD 179
G + +CVC G+ + DEC+ C C N G Y C CR+G+ D
Sbjct: 526 GGTCVAPNKCVCPSGFT-GSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFHDD 584
Query: 180 E----DGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGD 308
G +C D+DEC THTC C N G ++C C G GD
Sbjct: 585 GTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSGPSCSGD 633
Score = 49.2 bits (112), Expect = 9e-06
Identities = 30/80 (37%), Positives = 34/80 (42%), Gaps = 4/80 (5%)
Frame = +3
Query: 312 CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGY-RLDAEGARCVDRDECA-QTGRCQAP 485
C N C E C C N C C GY + + A C D DECA + C A
Sbjct: 389 CRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHAN 448
Query: 486 --CRNYAGGYRCDCPVGTVR 539
C N G YRCDC G +R
Sbjct: 449 TVCVNLPGLYRCDCVPGYIR 468
>U57523-1|AAB06946.1| 446|Homo sapiens protein ( Human nel homolog
mRNA, partial cds. ).
Length = 446
Score = 93.1 bits (221), Expect = 6e-19
Identities = 69/187 (36%), Positives = 87/187 (46%), Gaps = 13/187 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY-RPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELD 179
VN G +RC C PGY R DEC CD+ +C NT + C C+ GY
Sbjct: 70 VNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYV-- 127
Query: 180 EDGANCRDV-DECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGV-C 350
+G CR +E R TC + N +C C G+ G C DI+EC E + C
Sbjct: 128 GNGTICRAFCEEGCRYGGTC--VAPN-----KCVCPSGFT--GSHCEKDIDECSEGIIEC 178
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDA----EGARCVDRDECA-QTGRC--QAPCRNYAGGY 509
+ RCVNL G C C G+ D G C+D DECA +T C + C N AGG+
Sbjct: 179 HNHSRCVNLPGWHHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGF 238
Query: 510 RCDCPVG 530
C CP G
Sbjct: 239 DCLCPCG 245
Score = 82.6 bits (195), Expect = 8e-16
Identities = 56/157 (35%), Positives = 75/157 (47%), Gaps = 8/157 (5%)
Frame = +3
Query: 84 DECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICS 251
DECA + C + +C N G Y C C GY + D +C + DEC H C + IC+
Sbjct: 54 DECAAKMHYCHANTVCVNLPGLYRCDCVPGY-IRVDDFSCTEHDECGSGQHNCDENAICT 112
Query: 252 NTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEG 431
NT + C+C+ GY G C C EEG C G CV +CVCP G+ G
Sbjct: 113 NTVQGHSCTCKPGYVGNGTICRAF--C-EEG-CRYGGTCV---APNKCVCPSGF----TG 161
Query: 432 ARC-VDRDECAQ-TGRC--QAPCRNYAGGYRCDCPVG 530
+ C D DEC++ C + C N G + C+C G
Sbjct: 162 SHCEKDIDECSEGIIECHNHSRCVNLPGWHHCECRSG 198
Score = 67.3 bits (157), Expect = 3e-11
Identities = 38/120 (31%), Positives = 49/120 (40%), Gaps = 4/120 (3%)
Frame = +3
Query: 183 DGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGD-ACVDINECHE-EGVC 350
D A C D+DEC H C +C N G Y C C GY + D +C + +EC + C
Sbjct: 46 DSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNC 105
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
C N + C C GY + R + C G C AP +C CP G
Sbjct: 106 DENAICTNTVQGHSCTCKPGYVGNGTICRAFCEEGCRYGGTCVAP-------NKCVCPSG 158
Score = 58.8 bits (136), Expect = 1e-08
Identities = 35/109 (32%), Positives = 47/109 (43%), Gaps = 8/109 (7%)
Frame = +3
Query: 6 GVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELD 179
G + +CVC G+ + DEC+ C C N G + C CR+G+ D
Sbjct: 144 GGTCVAPNKCVCPSGFT-GSHCEKDIDECSEGIIECHNHSRCVNLPGWHHCECRSGFHDD 202
Query: 180 E----DGANCRDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGD 308
G +C D+DEC THTC C N G ++C C G GD
Sbjct: 203 GTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPCGPSCSGD 251
Score = 35.1 bits (77), Expect = 0.17
Identities = 19/41 (46%), Positives = 22/41 (53%), Gaps = 3/41 (7%)
Frame = +3
Query: 426 EGARCVDRDECA-QTGRCQAP--CRNYAGGYRCDCPVGTVR 539
+ A C D DECA + C A C N G YRCDC G +R
Sbjct: 46 DSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIR 86
>BC096103-1|AAH96103.1| 763|Homo sapiens NELL1 protein protein.
Length = 763
Score = 92.7 bits (220), Expect = 8e-19
Identities = 61/157 (38%), Positives = 78/157 (49%), Gaps = 8/157 (5%)
Frame = +3
Query: 84 DECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICS 251
DECA + C + +C N G Y C C GY + D +C + DEC H C + IC+
Sbjct: 436 DECAAKMHYCHANTVCVNLPGLYRCDCVPGY-IRVDDFSCTEHDECGSGQHNCDENAICT 494
Query: 252 NTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEG 431
NT + C+C+ GY G C C EEG C G CV +CVCP G+ G
Sbjct: 495 NTVQGHSCTCKPGYVGNGTICRAF--C-EEG-CRYGGTCV---APNKCVCPSGFT----G 543
Query: 432 ARCV-DRDECA-QTGRC--QAPCRNYAGGYRCDCPVG 530
+ C D DECA +T C + C N AGG+ C CP G
Sbjct: 544 SHCEKDIDECALRTHTCWNDSACINLAGGFDCLCPSG 580
Score = 82.2 bits (194), Expect = 1e-15
Identities = 51/162 (31%), Positives = 68/162 (41%), Gaps = 7/162 (4%)
Frame = +3
Query: 66 RGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGY-ELDEDGANCRDVDECERDTHTC 236
R RG + CA P C + C N + C C++GY + D A C D+DEC H C
Sbjct: 387 RVCRGHNFCA-EGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYC 445
Query: 237 QQ--ICSNTEGSYECSCEDGYEKRGD-ACVDINECHE-EGVCPSPGRCVNLLGSFRCVCP 404
+C N G Y C C GY + D +C + +EC + C C N + C C
Sbjct: 446 HANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCK 505
Query: 405 RGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
GY + R + C G C AP +C CP G
Sbjct: 506 PGYVGNGTICRAFCEEGCRYGGTCVAP-------NKCVCPSG 540
Score = 66.9 bits (156), Expect = 4e-11
Identities = 49/140 (35%), Positives = 63/140 (45%), Gaps = 6/140 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY-RPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELD 179
VN G +RC C PGY R DEC CD+ +C NT + C C+ GY
Sbjct: 452 VNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYV-- 509
Query: 180 EDGANCRDV-DECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECH-EEGVC 350
+G CR +E R TC + N +C C G+ G C DI+EC C
Sbjct: 510 GNGTICRAFCEEGCRYGGTC--VAPN-----KCVCPSGFT--GSHCEKDIDECALRTHTC 560
Query: 351 PSPGRCVNLLGSFRCVCPRG 410
+ C+NL G F C+CP G
Sbjct: 561 WNDSACINLAGGFDCLCPSG 580
Score = 50.8 bits (116), Expect = 3e-06
Identities = 33/102 (32%), Positives = 44/102 (43%), Gaps = 3/102 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
NT+ C C PGY G G R C C + C+C +G+ G+
Sbjct: 495 NTVQGHSCTCKPGY--VGNGTICRAFCE---EGC-RYGGTCVAPNKCVCPSGFT----GS 544
Query: 192 NC-RDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGD 308
+C +D+DEC THTC C N G ++C C G GD
Sbjct: 545 HCEKDIDECALRTHTCWNDSACINLAGGFDCLCPSGPSCSGD 586
Score = 49.2 bits (112), Expect = 9e-06
Identities = 30/80 (37%), Positives = 34/80 (42%), Gaps = 4/80 (5%)
Frame = +3
Query: 312 CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGY-RLDAEGARCVDRDECA-QTGRCQAP 485
C N C E C C N C C GY + + A C D DECA + C A
Sbjct: 389 CRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHAN 448
Query: 486 --CRNYAGGYRCDCPVGTVR 539
C N G YRCDC G +R
Sbjct: 449 TVCVNLPGLYRCDCVPGYIR 468
>BC096100-1|AAH96100.1| 763|Homo sapiens NELL1 protein protein.
Length = 763
Score = 92.7 bits (220), Expect = 8e-19
Identities = 61/157 (38%), Positives = 78/157 (49%), Gaps = 8/157 (5%)
Frame = +3
Query: 84 DECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICS 251
DECA + C + +C N G Y C C GY + D +C + DEC H C + IC+
Sbjct: 436 DECAAKMHYCHANTVCVNLPGLYRCDCVPGY-IRVDDFSCTEHDECGSGQHNCDENAICT 494
Query: 252 NTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEG 431
NT + C+C+ GY G C C EEG C G CV +CVCP G+ G
Sbjct: 495 NTVQGHSCTCKPGYVGNGTICRAF--C-EEG-CRYGGTCV---APNKCVCPSGFT----G 543
Query: 432 ARCV-DRDECA-QTGRC--QAPCRNYAGGYRCDCPVG 530
+ C D DECA +T C + C N AGG+ C CP G
Sbjct: 544 SHCEKDIDECALRTHTCWNDSACINLAGGFDCLCPSG 580
Score = 82.2 bits (194), Expect = 1e-15
Identities = 51/162 (31%), Positives = 68/162 (41%), Gaps = 7/162 (4%)
Frame = +3
Query: 66 RGVRGRDECAVRPPPCDQL--CHNTDGSYDCLCRTGY-ELDEDGANCRDVDECERDTHTC 236
R RG + CA P C + C N + C C++GY + D A C D+DEC H C
Sbjct: 387 RVCRGHNFCA-EGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYC 445
Query: 237 QQ--ICSNTEGSYECSCEDGYEKRGD-ACVDINECHE-EGVCPSPGRCVNLLGSFRCVCP 404
+C N G Y C C GY + D +C + +EC + C C N + C C
Sbjct: 446 HANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCK 505
Query: 405 RGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
GY + R + C G C AP +C CP G
Sbjct: 506 PGYVGNGTICRAFCEEGCRYGGTCVAP-------NKCVCPSG 540
Score = 66.9 bits (156), Expect = 4e-11
Identities = 49/140 (35%), Positives = 63/140 (45%), Gaps = 6/140 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY-RPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELD 179
VN G +RC C PGY R DEC CD+ +C NT + C C+ GY
Sbjct: 452 VNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYV-- 509
Query: 180 EDGANCRDV-DECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECH-EEGVC 350
+G CR +E R TC + N +C C G+ G C DI+EC C
Sbjct: 510 GNGTICRAFCEEGCRYGGTC--VAPN-----KCVCPSGFT--GSHCEKDIDECALRTHTC 560
Query: 351 PSPGRCVNLLGSFRCVCPRG 410
+ C+NL G F C+CP G
Sbjct: 561 WNDSACINLAGGFDCLCPSG 580
Score = 50.8 bits (116), Expect = 3e-06
Identities = 33/102 (32%), Positives = 44/102 (43%), Gaps = 3/102 (2%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
NT+ C C PGY G G R C C + C+C +G+ G+
Sbjct: 495 NTVQGHSCTCKPGY--VGNGTICRAFCE---EGC-RYGGTCVAPNKCVCPSGFT----GS 544
Query: 192 NC-RDVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGD 308
+C +D+DEC THTC C N G ++C C G GD
Sbjct: 545 HCEKDIDECALRTHTCWNDSACINLAGGFDCLCPSGPSCSGD 586
Score = 49.2 bits (112), Expect = 9e-06
Identities = 30/80 (37%), Positives = 34/80 (42%), Gaps = 4/80 (5%)
Frame = +3
Query: 312 CVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGY-RLDAEGARCVDRDECA-QTGRCQAP 485
C N C E C C N C C GY + + A C D DECA + C A
Sbjct: 389 CRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHAN 448
Query: 486 --CRNYAGGYRCDCPVGTVR 539
C N G YRCDC G +R
Sbjct: 449 TVCVNLPGLYRCDCVPGYIR 468
>AF029779-1|AAB84216.1| 1200|Homo sapiens hJAG2.del-E6 protein.
Length = 1200
Score = 92.7 bits (220), Expect = 8e-19
Identities = 54/174 (31%), Positives = 82/174 (47%), Gaps = 6/174 (3%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGV-RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 200
+RC C GY +GR + C P CH ++C C +G+ G C
Sbjct: 331 YRCTCPDGY--SGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWS----GPTCAL 384
Query: 201 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNL 377
D+DEC + C + +EC C + + G C +D+N+C G C G C +L
Sbjct: 385 DIDECASNPCAAGGTCVDQVDGFECICPEQWV--GATCQLDVNDCR--GQCQHGGTCKDL 440
Query: 378 LGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQAP--CRNYAGGYRCDCPVG 530
+ ++CVCPRG+ G C ++RD+CA + C + C + A G+ C CP G
Sbjct: 441 VNGYQCVCPRGF----GGRHCELERDKCA-SSPCHSGGLCEDLADGFHCHCPQG 489
Score = 70.1 bits (164), Expect = 5e-12
Identities = 51/183 (27%), Positives = 81/183 (44%), Gaps = 7/183 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRD-ECAVRPPPCDQLCHNTDGSYDCLCRTGYELD 179
R + + F C C G++ G+ R+ +C C+++ ++ C C G++
Sbjct: 650 RCYDLVNDFYCACDDGWK--GKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWK-- 705
Query: 180 EDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVC 350
G+ C + C C + S+ C C DG+E G C + N+C+ C
Sbjct: 706 --GSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWE--GRTCTHNTNDCNPLP-C 760
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDC 521
+ G CV+ + FRC C G+ G C ++ DEC Q+ C A C + GYRC C
Sbjct: 761 YNGGICVDGVNWFRCECAPGFA----GPDCRINIDEC-QSSPCAYGATCVDEINGYRCSC 815
Query: 522 PVG 530
P G
Sbjct: 816 PPG 818
Score = 68.1 bits (159), Expect = 2e-11
Identities = 52/171 (30%), Positives = 73/171 (42%), Gaps = 5/171 (2%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-D 203
F C C G+ + DECA P C + ++C+C + GA C+ D
Sbjct: 369 FECHCPSGWSGPTCAL-DIDECASNPCAAGGTCVDQVDGFECICPEQWV----GATCQLD 423
Query: 204 VDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNL 377
V++C CQ C + Y+C C G+ R ++ ++C C S G C +L
Sbjct: 424 VNDCRGQ---CQHGGTCKDLVNGYQCVCPRGFGGR-HCELERDKC-ASSPCHSGGLCEDL 478
Query: 378 LGSFRCVCPRGYRLDAEGARC-VDRDECAQTG-RCQAPCRNYAGGYRCDCP 524
F C CP+G+ G C VD D C + R A C N G Y C CP
Sbjct: 479 ADGFHCHCPQGF----SGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACP 525
Score = 64.1 bits (149), Expect = 3e-10
Identities = 49/174 (28%), Positives = 77/174 (44%), Gaps = 4/174 (2%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 200
G+ R + G G AG G+ G V P + G++ C+C +G+ G C
Sbjct: 543 GACRVIDGCG-SDAGPGMPGTAASGVCGPH-GRCVSQPGGNFSCICDSGFT----GTYCH 596
Query: 201 D-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVN 374
+ +D+C C + ++ C C G+E G+ C + N+C + C S GRC +
Sbjct: 597 ENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWE--GELCDTNPNDCLPDP-CHSRGRCYD 653
Query: 375 LLGSFRCVCPRGYRLDAEGARCVDRD-EC-AQTGRCQAPCRNYAGGYRCDCPVG 530
L+ F C C G++ G C R+ +C A T C + +RC CP G
Sbjct: 654 LVNDFYCACDDGWK----GKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPG 703
Score = 56.8 bits (131), Expect = 5e-08
Identities = 38/156 (24%), Positives = 66/156 (42%), Gaps = 4/156 (2%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 200
G+F C+C G+ D+C +P C + ++ C C +G+E + N
Sbjct: 580 GNFSCICDSGFTGTYCH-ENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPN 638
Query: 201 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLL 380
D C D + C + + C+C+DG+ +G C + C + G C +
Sbjct: 639 D---CLPDPCHSRGRCYDLVNDFYCACDDGW--KGKTCHSREFQCDAYTCSNGGTCYDSG 693
Query: 381 GSFRCVCPRGYR----LDAEGARCVDRDECAQTGRC 476
+FRC CP G++ A+ + C+ + C G C
Sbjct: 694 DTFRCACPPGWKGSTCAVAKNSSCLP-NPCVNGGTC 728
Score = 51.6 bits (118), Expect = 2e-06
Identities = 47/177 (26%), Positives = 70/177 (39%), Gaps = 27/177 (15%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGY-----ELDED 185
F C C G+ V D P PC C+N +G Y C C + + +
Sbjct: 482 FHCHCPQGFSGPLCEV---DVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPRE 538
Query: 186 ---GANCRDVDECERDTH------TCQQIC-------SNTEGSYECSCEDGYEKRGDACV 317
G CR +D C D +C S G++ C C+ G+ G C
Sbjct: 539 PCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFT--GTYCH 596
Query: 318 D-INECHEEGVCPSPGRCVNLLGSFRCVCPRGYR---LDAEGARCVDRDECAQTGRC 476
+ I++C + C + G C++ + +FRC CP G+ D C+ D C GRC
Sbjct: 597 ENIDDCLGQP-CRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLP-DPCHSRGRC 651
Score = 50.4 bits (115), Expect = 4e-06
Identities = 27/92 (29%), Positives = 38/92 (41%), Gaps = 4/92 (4%)
Frame = +3
Query: 267 YECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNL-LGSFRCVCPRGYRLDAEGARC 440
++C+CE + G C D+N C C + G C+N +RC CP GY G C
Sbjct: 291 WQCNCETNWG--GLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGY----SGRNC 344
Query: 441 VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
+ + C C G+ C CP G
Sbjct: 345 EKAEHACTSNPCANGGSCHEVPSGFECHCPSG 376
>Y14330-1|CAA74706.1| 1223|Homo sapiens jagged2 protein protein.
Length = 1223
Score = 92.3 bits (219), Expect = 1e-18
Identities = 56/173 (32%), Positives = 81/173 (46%), Gaps = 5/173 (2%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-D 203
F C C G+ DECA P C + ++C+C + GA C+ D
Sbjct: 353 FECHCPSGWSGPTCASADIDECASNPCAAGGTCVDQVDGFECICPEQWV----GATCQLD 408
Query: 204 VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNLL 380
+ECE C N G Y C C G+ +G C +++N+C G C G C +L+
Sbjct: 409 ANECEGKPCLNAFSCKNLIGGYYCDCIPGW--KGINCHINVNDCR--GQCQHGGTCKDLV 464
Query: 381 GSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQAP--CRNYAGGYRCDCPVG 530
++CVCPRG+ G C ++RDECA + C + C + A G+ C CP G
Sbjct: 465 NGYQCVCPRGF----GGRHCELERDECA-SSPCHSGGLCEDLADGFHCHCPQG 512
Score = 80.6 bits (190), Expect = 3e-15
Identities = 52/175 (29%), Positives = 79/175 (45%), Gaps = 7/175 (4%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGV-RGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-- 197
+RC C GY +GR + C P CH ++C C +G+ G C
Sbjct: 315 YRCTCPDGY--SGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGW----SGPTCAS 368
Query: 198 RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVN 374
D+DEC + C + +EC C + + G C +D NEC E C + C N
Sbjct: 369 ADIDECASNPCAAGGTCVDQVDGFECICPEQWV--GATCQLDANEC-EGKPCLNAFSCKN 425
Query: 375 LLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
L+G + C C G++ G C ++ ++C G+CQ C++ GY+C CP G
Sbjct: 426 LIGGYYCDCIPGWK----GINCHINVNDC--RGQCQHGGTCKDLVNGYQCVCPRG 474
Score = 73.7 bits (173), Expect = 4e-13
Identities = 47/147 (31%), Positives = 61/147 (41%), Gaps = 6/147 (4%)
Frame = +3
Query: 108 PCDQ--LCHNTD-GSYDCLCRTGYELDEDGANCRDVDE-CERDTHTCQQICSNTEGSYEC 275
PC C N + Y C C GY G NC + C + C +EC
Sbjct: 300 PCTNGGTCINAEPDQYRCTCPDGYS----GRNCEKAEHACTSNPCANGGSCHEVPSGFEC 355
Query: 276 SCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRD 452
C G+ A DI+EC C + G CV+ + F C+CP + GA C +D +
Sbjct: 356 HCPSGWSGPTCASADIDEC-ASNPCAAGGTCVDQVDGFECICPEQW----VGATCQLDAN 410
Query: 453 ECAQTGRCQA-PCRNYAGGYRCDCPVG 530
EC A C+N GGY CDC G
Sbjct: 411 ECEGKPCLNAFSCKNLIGGYYCDCIPG 437
Score = 70.9 bits (166), Expect = 3e-12
Identities = 55/177 (31%), Positives = 75/177 (42%), Gaps = 5/177 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
V+ + F C+C P +EC +P C N G Y C C G++ G
Sbjct: 386 VDQVDGFECIC-PEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWK----G 440
Query: 189 ANCR-DVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSP 359
NC +V++C CQ C + Y+C C G+ R ++ +EC C S
Sbjct: 441 INCHINVNDCRGQ---CQHGGTCKDLVNGYQCVCPRGFGGR-HCELERDEC-ASSPCHSG 495
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTG-RCQAPCRNYAGGYRCDCP 524
G C +L F C CP+G+ G C VD D C + R A C N G Y C CP
Sbjct: 496 GLCEDLADGFHCHCPQGF----SGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACP 548
Score = 70.1 bits (164), Expect = 5e-12
Identities = 51/183 (27%), Positives = 81/183 (44%), Gaps = 7/183 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRD-ECAVRPPPCDQLCHNTDGSYDCLCRTGYELD 179
R + + F C C G++ G+ R+ +C C+++ ++ C C G++
Sbjct: 673 RCYDLVNDFYCACDDGWK--GKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWK-- 728
Query: 180 EDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVC 350
G+ C + C C + S+ C C DG+E G C + N+C+ C
Sbjct: 729 --GSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWE--GRTCTHNTNDCNPLP-C 783
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDC 521
+ G CV+ + FRC C G+ G C ++ DEC Q+ C A C + GYRC C
Sbjct: 784 YNGGICVDGVNWFRCECAPGFA----GPDCRINIDEC-QSSPCAYGATCVDEINGYRCSC 838
Query: 522 PVG 530
P G
Sbjct: 839 PPG 841
Score = 64.1 bits (149), Expect = 3e-10
Identities = 49/174 (28%), Positives = 77/174 (44%), Gaps = 4/174 (2%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 200
G+ R + G G AG G+ G V P + G++ C+C +G+ G C
Sbjct: 566 GACRVIDGCG-SDAGPGMPGTAASGVCGPH-GRCVSQPGGNFSCICDSGFT----GTYCH 619
Query: 201 D-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVN 374
+ +D+C C + ++ C C G+E G+ C + N+C + C S GRC +
Sbjct: 620 ENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWE--GELCDTNPNDCLPDP-CHSRGRCYD 676
Query: 375 LLGSFRCVCPRGYRLDAEGARCVDRD-EC-AQTGRCQAPCRNYAGGYRCDCPVG 530
L+ F C C G++ G C R+ +C A T C + +RC CP G
Sbjct: 677 LVNDFYCACDDGWK----GKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPG 726
Score = 56.8 bits (131), Expect = 5e-08
Identities = 38/156 (24%), Positives = 66/156 (42%), Gaps = 4/156 (2%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 200
G+F C+C G+ D+C +P C + ++ C C +G+E + N
Sbjct: 603 GNFSCICDSGFTGTYCH-ENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPN 661
Query: 201 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLL 380
D C D + C + + C+C+DG+ +G C + C + G C +
Sbjct: 662 D---CLPDPCHSRGRCYDLVNDFYCACDDGW--KGKTCHSREFQCDAYTCSNGGTCYDSG 716
Query: 381 GSFRCVCPRGYR----LDAEGARCVDRDECAQTGRC 476
+FRC CP G++ A+ + C+ + C G C
Sbjct: 717 DTFRCACPPGWKGSTCAVAKNSSCLP-NPCVNGGTC 751
Score = 51.6 bits (118), Expect = 2e-06
Identities = 47/177 (26%), Positives = 70/177 (39%), Gaps = 27/177 (15%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGY-----ELDED 185
F C C G+ V D P PC C+N +G Y C C + + +
Sbjct: 505 FHCHCPQGFSGPLCEV---DVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPRE 561
Query: 186 ---GANCRDVDECERDTH------TCQQIC-------SNTEGSYECSCEDGYEKRGDACV 317
G CR +D C D +C S G++ C C+ G+ G C
Sbjct: 562 PCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFT--GTYCH 619
Query: 318 D-INECHEEGVCPSPGRCVNLLGSFRCVCPRGYR---LDAEGARCVDRDECAQTGRC 476
+ I++C + C + G C++ + +FRC CP G+ D C+ D C GRC
Sbjct: 620 ENIDDCLGQP-CRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLP-DPCHSRGRC 674
Score = 50.4 bits (115), Expect = 4e-06
Identities = 27/92 (29%), Positives = 38/92 (41%), Gaps = 4/92 (4%)
Frame = +3
Query: 267 YECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNL-LGSFRCVCPRGYRLDAEGARC 440
++C+CE + G C D+N C C + G C+N +RC CP GY G C
Sbjct: 275 WQCNCETNWG--GLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGY----SGRNC 328
Query: 441 VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
+ + C C G+ C CP G
Sbjct: 329 EKAEHACTSNPCANGGSCHEVPSGFECHCPSG 360
>U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein.
Length = 2003
Score = 91.9 bits (218), Expect = 1e-18
Identities = 65/186 (34%), Positives = 88/186 (47%), Gaps = 12/186 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNT--DGSYDCLCRTGYELDE 182
++ +GSF C+C PG G D C +P D C GS CLC+ GY
Sbjct: 371 IDRVGSFSCLCPPG--RTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGY---- 424
Query: 183 DGANC-RDVDEC---ERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC-VDINECHEE 341
G C +D+DEC ++ C+ C NT GS+ C C GY G C D NEC +
Sbjct: 425 SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY--TGSRCEADHNECLSQ 482
Query: 342 GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRC--QAPCRNYAGGYR 512
C C++LL +F C+CP G EG C V+ +ECA + C A C + G++
Sbjct: 483 -PCHPGSTCLDLLATFHCLCPPG----LEGQLCEVETNECA-SAPCLNHADCHDLLNGFQ 536
Query: 513 CDCPVG 530
C C G
Sbjct: 537 CICLPG 542
Score = 83.8 bits (198), Expect = 4e-16
Identities = 57/179 (31%), Positives = 76/179 (42%), Gaps = 8/179 (4%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQL--CH-NTDGSYDCLCRTGYELDEDGAN 194
SF C C PG+ + D C P C + CH G C C G+ G
Sbjct: 100 SFLCTCLPGFTGERCQAKLEDPCP--PSFCSKRGRCHIQASGRPQCSCMPGWT----GEQ 153
Query: 195 CRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEE-GVCPSPGRC 368
C+ D C + +C T +C C G+E G AC D+NEC ++ G CP C
Sbjct: 154 CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFE--GHACERDVNECFQDPGPCPKGTSC 211
Query: 369 VNLLGSFRCVCP---RGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTV 536
N LGSF+C+CP G R + C R C+ G CQ + + C CP G +
Sbjct: 212 HNTLGSFQCLCPVGQEGPRCELRAGPCPPRG-CSNGGTCQLMPEKDSTFHLCLCPPGFI 269
Score = 82.2 bits (194), Expect = 1e-15
Identities = 61/182 (33%), Positives = 79/182 (43%), Gaps = 9/182 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N+ GSF CVC G+ D+C C + GS+ CLC G G
Sbjct: 334 NSAGSFHCVCVSGWGGTSCE-ENLDDCIAATCAPGSTCIDRVGSFSCLCPPG----RTGL 388
Query: 192 NCRDVDEC-ERDTHTCQQICSNT-EGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSP- 359
C D C + H Q +N GS C C+ GY G C D++EC PSP
Sbjct: 389 LCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS--GPTCHQDLDECLMAQQGPSPC 446
Query: 360 ---GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDEC-AQTGRCQAPCRNYAGGYRCDCP 524
G C+N GSF C+CP GY G+RC D +EC +Q + C + + C CP
Sbjct: 447 EHGGSCLNTPGSFNCLCPPGY----TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCP 502
Query: 525 VG 530
G
Sbjct: 503 PG 504
Score = 81.4 bits (192), Expect = 2e-15
Identities = 56/178 (31%), Positives = 79/178 (44%), Gaps = 4/178 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+NT GSF C+C PGY R +EC +P C + ++ CLC G E G
Sbjct: 453 LNTPGSFNCLCPPGY-TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLE----G 507
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
C + +EC C + ++C C G+ G C DI+EC C + G
Sbjct: 508 QLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFS--GTRCEEDIDEC-RSSPCANGG 564
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARC-VDRDEC-AQTGRCQAPCRNYAGGYRCDCPVG 530
+C + G+F C C G+ EG RC + DEC + A C + G + C CP G
Sbjct: 565 QCQDQPGAFHCKCLPGF----EGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSG 618
Score = 78.2 bits (184), Expect = 2e-14
Identities = 52/179 (29%), Positives = 80/179 (44%), Gaps = 4/179 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ + +F C+C PG V +ECA P CH+ + C+C G+ G
Sbjct: 491 LDLLATFHCLCPPGLEGQLCEVE-TNECASAPCLNHADCHDLLNGFQCICLPGFS----G 545
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
C D+DEC C + G++ C C G+E G C +++EC + CP
Sbjct: 546 TRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE--GPRCQTEVDECLSDP-CPVGA 602
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRCDCPVGT 533
C++L G+F C+CP G+ G C + CA CQ C++ C CP G+
Sbjct: 603 SCLDLPGAFFCLCPSGF----TGQLC-EVPLCA-PNLCQPKQICKDQKDKANCLCPDGS 655
Score = 70.9 bits (166), Expect = 3e-12
Identities = 60/191 (31%), Positives = 84/191 (43%), Gaps = 18/191 (9%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCD----------QLCHNTDGSYD-CLC 158
NT+GSF+C+C G G R C +R PC QL D ++ CLC
Sbjct: 213 NTLGSFQCLCPVGQE----GPR----CELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLC 264
Query: 159 RTGYELDEDGANCR-DVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACVDINE 329
G+ G +C + D C +H CQ C + +Y C C + + D D++E
Sbjct: 265 PPGFI----GPDCEVNPDNCV--SHQCQNGGTCQDGLDTYTCLCPETWTG-WDCSEDVDE 317
Query: 330 CHEEGV--CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DEC-AQTGRCQAPCRNY 497
C +G C + G C N GSF CVC G+ G C + D+C A T + C +
Sbjct: 318 CETQGPPHCRNGGTCQNSAGSFHCVCVSGW----GGTSCEENLDDCIAATCAPGSTCIDR 373
Query: 498 AGGYRCDCPVG 530
G + C CP G
Sbjct: 374 VGSFSCLCPPG 384
Score = 70.1 bits (164), Expect = 5e-12
Identities = 53/187 (28%), Positives = 80/187 (42%), Gaps = 13/187 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
VN G+F C+C G++ + R CA P C ++ CLC TGY G
Sbjct: 783 VNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGY----TG 838
Query: 189 ANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHE----EGV- 347
+C+ +D C + C T S+ C C G+ G C + ++ C + +G+
Sbjct: 839 GSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGW--TGPLCNLPLSSCQKAALSQGID 896
Query: 348 ----CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ--APCRNYAGGY 509
C + G CV+ S+ C CP G+ +G+ C D ++ CQ A C GY
Sbjct: 897 VSSLCHNGGLCVDSGPSYFCHCPPGF----QGSLCQDHVNPCESRPCQNGATCMAQPSGY 952
Query: 510 RCDCPVG 530
C C G
Sbjct: 953 LCQCAPG 959
Score = 68.1 bits (159), Expect = 2e-11
Identities = 50/171 (29%), Positives = 69/171 (40%), Gaps = 5/171 (2%)
Frame = +3
Query: 33 CVCGPGYR-PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-RDV 206
CVC G+ P G C P C+ Y+C C TGY G C ++
Sbjct: 677 CVCDVGWTGPECEAELGG--CISAPCAHGGTCYPQPSGYNCTCPTGYT----GPTCSEEM 730
Query: 207 DECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGS 386
C C+ + G Y C+C + G C + C + G CVN G+
Sbjct: 731 TACHSGPCLNGGSCNPSPGGYYCTCPPSHT--GPQCQTSTDYCVSAPCFNGGTCVNRPGT 788
Query: 387 FRCVCPRGYRLDAEGARCVD--RDECAQTG-RCQAPCRNYAGGYRCDCPVG 530
F C+C G+ +G RC R CA + R +A C++ G RC CP G
Sbjct: 789 FSCLCAMGF----QGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTG 835
Score = 67.7 bits (158), Expect = 3e-11
Identities = 52/183 (28%), Positives = 74/183 (40%), Gaps = 14/183 (7%)
Frame = +3
Query: 30 RCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DV 206
RC+C GY G D CA +P P + C T S+ CLC G+ G C +
Sbjct: 829 RCLCPTGYT-GGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWT----GPLCNLPL 883
Query: 207 DECERD--------THTCQQ--ICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCP 353
C++ + C +C ++ SY C C G++ G C D +N C E C
Sbjct: 884 SSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLCQDHVNPC-ESRPCQ 940
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ--APCRNYAGGYRCDCPV 527
+ C+ + C C GY +G C + Q+ C C GG+ C CP
Sbjct: 941 NGATCMAQPSGYLCQCAPGY----DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPP 996
Query: 528 GTV 536
G V
Sbjct: 997 GFV 999
Score = 66.1 bits (154), Expect = 8e-11
Identities = 45/144 (31%), Positives = 66/144 (45%), Gaps = 7/144 (4%)
Frame = +3
Query: 120 LCHNTDGSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQ--ICSNTEGSYECSCEDG 290
LC ++ SY C C G++ G+ C+D V+ CE + CQ C Y C C G
Sbjct: 906 LCVDSGPSYFCHCPPGFQ----GSLCQDHVNPCE--SRPCQNGATCMAQPSGYLCQCAPG 959
Query: 291 YEKRGDACV-DINECHEEGVCPSPGRCVNLLGSFRCVCPRGY---RLDAEGARCVDRDEC 458
Y+ G C +++ C + C + G C G F C CP G+ R + + C+D+ C
Sbjct: 960 YD--GQNCSKELDACQSQP-CHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQ-PC 1015
Query: 459 AQTGRCQAPCRNYAGGYRCDCPVG 530
TG A C + A + C C G
Sbjct: 1016 HPTG--TAACHSLANAFYCQCLPG 1037
Score = 60.9 bits (141), Expect = 3e-09
Identities = 52/188 (27%), Positives = 74/188 (39%), Gaps = 20/188 (10%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGR-DECAVRP--PPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
G F C C PG+ G G DEC +P P CH+ ++ C C G+ G
Sbjct: 988 GGFHCACPPGF--VGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT----GQ 1041
Query: 192 NCR-DVDECERDTHTCQQICSNTEGS---YECSCEDGYE-----KRGDACVDINECHEEG 344
C ++D C C T GS + C C G+E R +C + CH G
Sbjct: 1042 WCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSC-GFHHCHHGG 1100
Query: 345 VC---PSPG-----RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYA 500
+C P PG C++ G C+ P + + C+ C++T P
Sbjct: 1101 LCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGP----- 1155
Query: 501 GGYRCDCP 524
G+RC CP
Sbjct: 1156 -GFRCSCP 1162
>U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein.
Length = 1999
Score = 91.9 bits (218), Expect = 1e-18
Identities = 65/186 (34%), Positives = 88/186 (47%), Gaps = 12/186 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNT--DGSYDCLCRTGYELDE 182
++ +GSF C+C PG G D C +P D C GS CLC+ GY
Sbjct: 370 IDRVGSFSCLCPPG--RTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGY---- 423
Query: 183 DGANC-RDVDEC---ERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC-VDINECHEE 341
G C +D+DEC ++ C+ C NT GS+ C C GY G C D NEC +
Sbjct: 424 SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY--TGSRCEADHNECLSQ 481
Query: 342 GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRC--QAPCRNYAGGYR 512
C C++LL +F C+CP G EG C V+ +ECA + C A C + G++
Sbjct: 482 -PCHPGSTCLDLLATFHCLCPPG----LEGQLCEVETNECA-SAPCLNHADCHDLLNGFQ 535
Query: 513 CDCPVG 530
C C G
Sbjct: 536 CICLPG 541
Score = 83.8 bits (198), Expect = 4e-16
Identities = 57/179 (31%), Positives = 76/179 (42%), Gaps = 8/179 (4%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQL--CH-NTDGSYDCLCRTGYELDEDGAN 194
SF C C PG+ + D C P C + CH G C C G+ G
Sbjct: 99 SFLCTCLPGFTGERCQAKLEDPCP--PSFCSKRGRCHIQASGRPQCSCMPGWT----GEQ 152
Query: 195 CRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEE-GVCPSPGRC 368
C+ D C + +C T +C C G+E G AC D+NEC ++ G CP C
Sbjct: 153 CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFE--GHACERDVNECFQDPGPCPKGTSC 210
Query: 369 VNLLGSFRCVCP---RGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTV 536
N LGSF+C+CP G R + C R C+ G CQ + + C CP G +
Sbjct: 211 HNTLGSFQCLCPVGQEGPRCELRAGPCPPRG-CSNGGTCQLMPEKDSTFHLCLCPPGFI 268
Score = 82.2 bits (194), Expect = 1e-15
Identities = 61/182 (33%), Positives = 79/182 (43%), Gaps = 9/182 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N+ GSF CVC G+ D+C C + GS+ CLC G G
Sbjct: 333 NSAGSFHCVCVSGWGGTSCE-ENLDDCIAATCAPGSTCIDRVGSFSCLCPPG----RTGL 387
Query: 192 NCRDVDEC-ERDTHTCQQICSNT-EGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSP- 359
C D C + H Q +N GS C C+ GY G C D++EC PSP
Sbjct: 388 LCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS--GPTCHQDLDECLMAQQGPSPC 445
Query: 360 ---GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDEC-AQTGRCQAPCRNYAGGYRCDCP 524
G C+N GSF C+CP GY G+RC D +EC +Q + C + + C CP
Sbjct: 446 EHGGSCLNTPGSFNCLCPPGY----TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCP 501
Query: 525 VG 530
G
Sbjct: 502 PG 503
Score = 81.4 bits (192), Expect = 2e-15
Identities = 56/178 (31%), Positives = 79/178 (44%), Gaps = 4/178 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+NT GSF C+C PGY R +EC +P C + ++ CLC G E G
Sbjct: 452 LNTPGSFNCLCPPGY-TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLE----G 506
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
C + +EC C + ++C C G+ G C DI+EC C + G
Sbjct: 507 QLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFS--GTRCEEDIDEC-RSSPCANGG 563
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARC-VDRDEC-AQTGRCQAPCRNYAGGYRCDCPVG 530
+C + G+F C C G+ EG RC + DEC + A C + G + C CP G
Sbjct: 564 QCQDQPGAFHCKCLPGF----EGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSG 617
Score = 78.2 bits (184), Expect = 2e-14
Identities = 52/179 (29%), Positives = 80/179 (44%), Gaps = 4/179 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ + +F C+C PG V +ECA P CH+ + C+C G+ G
Sbjct: 490 LDLLATFHCLCPPGLEGQLCEVE-TNECASAPCLNHADCHDLLNGFQCICLPGFS----G 544
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
C D+DEC C + G++ C C G+E G C +++EC + CP
Sbjct: 545 TRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE--GPRCQTEVDECLSDP-CPVGA 601
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRCDCPVGT 533
C++L G+F C+CP G+ G C + CA CQ C++ C CP G+
Sbjct: 602 SCLDLPGAFFCLCPSGF----TGQLC-EVPLCA-PNLCQPKQICKDQKDKANCLCPDGS 654
Score = 70.5 bits (165), Expect = 4e-12
Identities = 60/191 (31%), Positives = 83/191 (43%), Gaps = 18/191 (9%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCD----------QLCHNTDGSYD-CLC 158
NT+GSF+C+C G G R C +R PC QL D ++ CLC
Sbjct: 212 NTLGSFQCLCPVGQE----GPR----CELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLC 263
Query: 159 RTGYELDEDGANCR-DVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACVDINE 329
G+ G C + D C +H CQ C + +Y C C + + D D++E
Sbjct: 264 PPGFI----GPGCEVNPDNCV--SHQCQNGGTCQDGLDTYTCLCPETWTG-WDCSEDVDE 316
Query: 330 CHEEGV--CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DEC-AQTGRCQAPCRNY 497
C +G C + G C N GSF CVC G+ G C + D+C A T + C +
Sbjct: 317 CEAQGPPHCRNGGTCQNSAGSFHCVCVSGW----GGTSCEENLDDCIAATCAPGSTCIDR 372
Query: 498 AGGYRCDCPVG 530
G + C CP G
Sbjct: 373 VGSFSCLCPPG 383
Score = 70.1 bits (164), Expect = 5e-12
Identities = 53/187 (28%), Positives = 80/187 (42%), Gaps = 13/187 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
VN G+F C+C G++ + R CA P C ++ CLC TGY G
Sbjct: 782 VNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGY----TG 837
Query: 189 ANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHE----EGV- 347
+C+ +D C + C T S+ C C G+ G C + ++ C + +G+
Sbjct: 838 GSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGW--TGPLCNLPLSSCQKAALSQGID 895
Query: 348 ----CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ--APCRNYAGGY 509
C + G CV+ S+ C CP G+ +G+ C D ++ CQ A C GY
Sbjct: 896 VSSLCHNGGLCVDSGPSYFCHCPPGF----QGSLCQDHVNPCESRPCQNGATCMAQPSGY 951
Query: 510 RCDCPVG 530
C C G
Sbjct: 952 LCQCAPG 958
Score = 68.1 bits (159), Expect = 2e-11
Identities = 50/171 (29%), Positives = 69/171 (40%), Gaps = 5/171 (2%)
Frame = +3
Query: 33 CVCGPGYR-PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-RDV 206
CVC G+ P G C P C+ Y+C C TGY G C ++
Sbjct: 676 CVCDVGWTGPECEAELGG--CISAPCAHGGTCYPQPSGYNCTCPTGYT----GPTCSEEM 729
Query: 207 DECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGS 386
C C+ + G Y C+C + G C + C + G CVN G+
Sbjct: 730 TACHSGPCLNGGSCNPSPGGYYCTCPPSHT--GPQCQTSTDYCVSAPCFNGGTCVNRPGT 787
Query: 387 FRCVCPRGYRLDAEGARCVD--RDECAQTG-RCQAPCRNYAGGYRCDCPVG 530
F C+C G+ +G RC R CA + R +A C++ G RC CP G
Sbjct: 788 FSCLCAMGF----QGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTG 834
Score = 67.7 bits (158), Expect = 3e-11
Identities = 52/183 (28%), Positives = 74/183 (40%), Gaps = 14/183 (7%)
Frame = +3
Query: 30 RCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DV 206
RC+C GY G D CA +P P + C T S+ CLC G+ G C +
Sbjct: 828 RCLCPTGYT-GGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWT----GPLCNLPL 882
Query: 207 DECERD--------THTCQQ--ICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCP 353
C++ + C +C ++ SY C C G++ G C D +N C E C
Sbjct: 883 SSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLCQDHVNPC-ESRPCQ 939
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ--APCRNYAGGYRCDCPV 527
+ C+ + C C GY +G C + Q+ C C GG+ C CP
Sbjct: 940 NGATCMAQPSGYLCQCAPGY----DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPP 995
Query: 528 GTV 536
G V
Sbjct: 996 GFV 998
Score = 66.1 bits (154), Expect = 8e-11
Identities = 45/144 (31%), Positives = 66/144 (45%), Gaps = 7/144 (4%)
Frame = +3
Query: 120 LCHNTDGSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQ--ICSNTEGSYECSCEDG 290
LC ++ SY C C G++ G+ C+D V+ CE + CQ C Y C C G
Sbjct: 905 LCVDSGPSYFCHCPPGFQ----GSLCQDHVNPCE--SRPCQNGATCMAQPSGYLCQCAPG 958
Query: 291 YEKRGDACV-DINECHEEGVCPSPGRCVNLLGSFRCVCPRGY---RLDAEGARCVDRDEC 458
Y+ G C +++ C + C + G C G F C CP G+ R + + C+D+ C
Sbjct: 959 YD--GQNCSKELDACQSQP-CHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQ-PC 1014
Query: 459 AQTGRCQAPCRNYAGGYRCDCPVG 530
TG A C + A + C C G
Sbjct: 1015 HPTG--TAACHSLANAFYCQCLPG 1036
Score = 60.9 bits (141), Expect = 3e-09
Identities = 52/188 (27%), Positives = 74/188 (39%), Gaps = 20/188 (10%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGR-DECAVRP--PPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
G F C C PG+ G G DEC +P P CH+ ++ C C G+ G
Sbjct: 987 GGFHCACPPGF--VGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT----GQ 1040
Query: 192 NCR-DVDECERDTHTCQQICSNTEGS---YECSCEDGYE-----KRGDACVDINECHEEG 344
C ++D C C T GS + C C G+E R +C + CH G
Sbjct: 1041 WCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSC-GFHHCHHGG 1099
Query: 345 VC---PSPG-----RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYA 500
+C P PG C++ G C+ P + + C+ C++T P
Sbjct: 1100 LCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGP----- 1154
Query: 501 GGYRCDCP 524
G+RC CP
Sbjct: 1155 -GFRCSCP 1161
>D86566-1|BAA13116.1| 955|Homo sapiens notch related protein
protein.
Length = 955
Score = 91.9 bits (218), Expect = 1e-18
Identities = 65/186 (34%), Positives = 88/186 (47%), Gaps = 12/186 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNT--DGSYDCLCRTGYELDE 182
++ +GSF C+C PG G D C +P D C GS CLC+ GY
Sbjct: 371 IDRVGSFSCLCPPG--RTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGY---- 424
Query: 183 DGANC-RDVDEC---ERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC-VDINECHEE 341
G C +D+DEC ++ C+ C NT GS+ C C GY G C D NEC +
Sbjct: 425 SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY--TGSRCEADHNECLSQ 482
Query: 342 GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRC--QAPCRNYAGGYR 512
C C++LL +F C+CP G EG C V+ +ECA + C A C + G++
Sbjct: 483 -PCHPGSTCLDLLATFHCLCPPG----LEGQLCEVETNECA-SAPCLNHADCHDLLNGFQ 536
Query: 513 CDCPVG 530
C C G
Sbjct: 537 CICLPG 542
Score = 83.4 bits (197), Expect = 5e-16
Identities = 57/179 (31%), Positives = 76/179 (42%), Gaps = 8/179 (4%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQL--CH-NTDGSYDCLCRTGYELDEDGAN 194
SF C C PG+ + D C P C + CH G C C G+ G
Sbjct: 100 SFLCTCLPGFTGERCQAQLEDPCP--PSFCSKRGRCHIQASGRPQCSCMPGWT----GEQ 153
Query: 195 CRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEE-GVCPSPGRC 368
C+ D C + +C T +C C G+E G AC D+NEC ++ G CP C
Sbjct: 154 CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFE--GHACERDVNECFQDPGPCPKGTSC 211
Query: 369 VNLLGSFRCVCP---RGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTV 536
N LGSF+C+CP G R + C R C+ G CQ + + C CP G +
Sbjct: 212 HNTLGSFQCLCPVGQEGPRCELRAGPCPPRG-CSNGGTCQLMPEKDSTFHLCLCPPGFI 269
Score = 82.2 bits (194), Expect = 1e-15
Identities = 61/182 (33%), Positives = 79/182 (43%), Gaps = 9/182 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N+ GSF CVC G+ D+C C + GS+ CLC G G
Sbjct: 334 NSAGSFHCVCVSGWGGTSCE-ENLDDCIAATCAPGSTCIDRVGSFSCLCPPG----RTGL 388
Query: 192 NCRDVDEC-ERDTHTCQQICSNT-EGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSP- 359
C D C + H Q +N GS C C+ GY G C D++EC PSP
Sbjct: 389 LCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS--GPTCHQDLDECLMAQQGPSPC 446
Query: 360 ---GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDEC-AQTGRCQAPCRNYAGGYRCDCP 524
G C+N GSF C+CP GY G+RC D +EC +Q + C + + C CP
Sbjct: 447 EHGGSCLNTPGSFNCLCPPGY----TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCP 502
Query: 525 VG 530
G
Sbjct: 503 PG 504
Score = 81.4 bits (192), Expect = 2e-15
Identities = 56/178 (31%), Positives = 79/178 (44%), Gaps = 4/178 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+NT GSF C+C PGY R +EC +P C + ++ CLC G E G
Sbjct: 453 LNTPGSFNCLCPPGY-TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLE----G 507
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
C + +EC C + ++C C G+ G C DI+EC C + G
Sbjct: 508 QLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFS--GTRCEEDIDEC-RSSPCANGG 564
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARC-VDRDEC-AQTGRCQAPCRNYAGGYRCDCPVG 530
+C + G+F C C G+ EG RC + DEC + A C + G + C CP G
Sbjct: 565 QCQDQPGAFHCKCLPGF----EGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSG 618
Score = 78.2 bits (184), Expect = 2e-14
Identities = 52/179 (29%), Positives = 80/179 (44%), Gaps = 4/179 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ + +F C+C PG V +ECA P CH+ + C+C G+ G
Sbjct: 491 LDLLATFHCLCPPGLEGQLCEVE-TNECASAPCLNHADCHDLLNGFQCICLPGFS----G 545
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
C D+DEC C + G++ C C G+E G C +++EC + CP
Sbjct: 546 TRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE--GPRCQTEVDECLSDP-CPVGA 602
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRCDCPVGT 533
C++L G+F C+CP G+ G C + CA CQ C++ C CP G+
Sbjct: 603 SCLDLPGAFFCLCPSGF----TGQLC-EVPLCA-PNLCQPKQICKDQKDKANCLCPDGS 655
Score = 70.9 bits (166), Expect = 3e-12
Identities = 60/191 (31%), Positives = 84/191 (43%), Gaps = 18/191 (9%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCD----------QLCHNTDGSYD-CLC 158
NT+GSF+C+C G G R C +R PC QL D ++ CLC
Sbjct: 213 NTLGSFQCLCPVGQE----GPR----CELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLC 264
Query: 159 RTGYELDEDGANCR-DVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACVDINE 329
G+ G +C + D C +H CQ C + +Y C C + + D D++E
Sbjct: 265 PPGFI----GPDCEVNPDNCV--SHQCQNGGTCQDGLDTYTCLCPETWTG-WDCSEDVDE 317
Query: 330 CHEEGV--CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DEC-AQTGRCQAPCRNY 497
C +G C + G C N GSF CVC G+ G C + D+C A T + C +
Sbjct: 318 CETQGPPHCRNGGTCQNSAGSFHCVCVSGW----GGTSCEENLDDCIAATCAPGSTCIDR 373
Query: 498 AGGYRCDCPVG 530
G + C CP G
Sbjct: 374 VGSFSCLCPPG 384
Score = 68.1 bits (159), Expect = 2e-11
Identities = 50/171 (29%), Positives = 69/171 (40%), Gaps = 5/171 (2%)
Frame = +3
Query: 33 CVCGPGYR-PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-RDV 206
CVC G+ P G C P C+ Y+C C TGY G C ++
Sbjct: 677 CVCDVGWTGPECEAELGG--CISAPCAHGGTCYPQPSGYNCTCPTGYT----GPTCSEEM 730
Query: 207 DECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGS 386
C C+ + G Y C+C + G C + C + G CVN G+
Sbjct: 731 TACHSGPCLNGGSCNPSPGGYYCTCPPSHT--GPQCQTSTDYCVSAPCFNGGTCVNRPGT 788
Query: 387 FRCVCPRGYRLDAEGARCVD--RDECAQTG-RCQAPCRNYAGGYRCDCPVG 530
F C+C G+ +G RC R CA + R +A C++ G RC CP G
Sbjct: 789 FSCLCAMGF----QGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTG 835
Score = 64.9 bits (151), Expect = 2e-10
Identities = 51/182 (28%), Positives = 78/182 (42%), Gaps = 13/182 (7%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
VN G+F C+C G++ + R CA P C ++ CLC TGY G
Sbjct: 783 VNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGY----TG 838
Query: 189 ANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHE----EGV- 347
+C+ +D C + C T S+ C C G+ G C + ++ C + +G+
Sbjct: 839 GSCQTLMDLCAQRPCPRNSHCLQTGPSFHCLCLQGW--TGPLCNLPLSSCQKAALSQGID 896
Query: 348 ----CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ--APCRNYAGGY 509
C + G CV+ S+ C CP G+ +G+ C D ++ CQ A C GY
Sbjct: 897 VSSLCHNGGLCVDSGPSYFCHCPPGF----QGSLCQDHVNPCESRPCQNGATCMAQPSGY 952
Query: 510 RC 515
C
Sbjct: 953 LC 954
>BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 91.9 bits (218), Expect = 1e-18
Identities = 65/186 (34%), Positives = 88/186 (47%), Gaps = 12/186 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNT--DGSYDCLCRTGYELDE 182
++ +GSF C+C PG G D C +P D C GS CLC+ GY
Sbjct: 371 IDRVGSFSCLCPPG--RTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGY---- 424
Query: 183 DGANC-RDVDEC---ERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC-VDINECHEE 341
G C +D+DEC ++ C+ C NT GS+ C C GY G C D NEC +
Sbjct: 425 SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY--TGSRCEADHNECLSQ 482
Query: 342 GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRC--QAPCRNYAGGYR 512
C C++LL +F C+CP G EG C V+ +ECA + C A C + G++
Sbjct: 483 -PCHPGSTCLDLLATFHCLCPPG----LEGQLCEVETNECA-SAPCLNHADCHDLLNGFQ 536
Query: 513 CDCPVG 530
C C G
Sbjct: 537 CICLPG 542
Score = 83.8 bits (198), Expect = 4e-16
Identities = 57/179 (31%), Positives = 76/179 (42%), Gaps = 8/179 (4%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQL--CH-NTDGSYDCLCRTGYELDEDGAN 194
SF C C PG+ + D C P C + CH G C C G+ G
Sbjct: 100 SFLCTCLPGFTGERCQAKLEDPCP--PSFCSKRGRCHIQASGRPQCSCMPGWT----GEQ 153
Query: 195 CRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEE-GVCPSPGRC 368
C+ D C + +C T +C C G+E G AC D+NEC ++ G CP C
Sbjct: 154 CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFE--GHACERDVNECFQDPGPCPKGTSC 211
Query: 369 VNLLGSFRCVCP---RGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTV 536
N LGSF+C+CP G R + C R C+ G CQ + + C CP G +
Sbjct: 212 HNTLGSFQCLCPVGQEGPRCELRAGPCPPRG-CSNGGTCQLMPEKDSTFHLCLCPPGFI 269
Score = 82.2 bits (194), Expect = 1e-15
Identities = 61/182 (33%), Positives = 79/182 (43%), Gaps = 9/182 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N+ GSF CVC G+ D+C C + GS+ CLC G G
Sbjct: 334 NSAGSFHCVCVSGWGGTSCE-ENLDDCIAATCAPGSTCIDRVGSFSCLCPPG----RTGL 388
Query: 192 NCRDVDEC-ERDTHTCQQICSNT-EGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSP- 359
C D C + H Q +N GS C C+ GY G C D++EC PSP
Sbjct: 389 LCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS--GPTCHQDLDECLMAQQGPSPC 446
Query: 360 ---GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDEC-AQTGRCQAPCRNYAGGYRCDCP 524
G C+N GSF C+CP GY G+RC D +EC +Q + C + + C CP
Sbjct: 447 EHGGSCLNTPGSFNCLCPPGY----TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCP 502
Query: 525 VG 530
G
Sbjct: 503 PG 504
Score = 81.4 bits (192), Expect = 2e-15
Identities = 56/178 (31%), Positives = 79/178 (44%), Gaps = 4/178 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+NT GSF C+C PGY R +EC +P C + ++ CLC G E G
Sbjct: 453 LNTPGSFNCLCPPGY-TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLE----G 507
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
C + +EC C + ++C C G+ G C DI+EC C + G
Sbjct: 508 QLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFS--GTRCEEDIDEC-RSSPCANGG 564
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARC-VDRDEC-AQTGRCQAPCRNYAGGYRCDCPVG 530
+C + G+F C C G+ EG RC + DEC + A C + G + C CP G
Sbjct: 565 QCQDQPGAFHCKCLPGF----EGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSG 618
Score = 78.2 bits (184), Expect = 2e-14
Identities = 52/179 (29%), Positives = 80/179 (44%), Gaps = 4/179 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ + +F C+C PG V +ECA P CH+ + C+C G+ G
Sbjct: 491 LDLLATFHCLCPPGLEGQLCEVE-TNECASAPCLNHADCHDLLNGFQCICLPGFS----G 545
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
C D+DEC C + G++ C C G+E G C +++EC + CP
Sbjct: 546 TRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE--GPRCQTEVDECLSDP-CPVGA 602
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRCDCPVGT 533
C++L G+F C+CP G+ G C + CA CQ C++ C CP G+
Sbjct: 603 SCLDLPGAFFCLCPSGF----TGQLC-EVPLCA-PNLCQPKQICKDQKDKANCLCPDGS 655
Score = 70.9 bits (166), Expect = 3e-12
Identities = 60/191 (31%), Positives = 84/191 (43%), Gaps = 18/191 (9%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCD----------QLCHNTDGSYD-CLC 158
NT+GSF+C+C G G R C +R PC QL D ++ CLC
Sbjct: 213 NTLGSFQCLCPVGQE----GPR----CELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLC 264
Query: 159 RTGYELDEDGANCR-DVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACVDINE 329
G+ G +C + D C +H CQ C + +Y C C + + D D++E
Sbjct: 265 PPGFI----GPDCEVNPDNCV--SHQCQNGGTCQDGLDTYTCLCPETWTG-WDCSEDVDE 317
Query: 330 CHEEGV--CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DEC-AQTGRCQAPCRNY 497
C +G C + G C N GSF CVC G+ G C + D+C A T + C +
Sbjct: 318 CETQGPPHCRNGGTCQNSAGSFHCVCVSGW----GGTSCEENLDDCIAATCAPGSTCIDR 373
Query: 498 AGGYRCDCPVG 530
G + C CP G
Sbjct: 374 VGSFSCLCPPG 384
Score = 70.1 bits (164), Expect = 5e-12
Identities = 53/187 (28%), Positives = 80/187 (42%), Gaps = 13/187 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
VN G+F C+C G++ + R CA P C ++ CLC TGY G
Sbjct: 783 VNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGY----TG 838
Query: 189 ANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHE----EGV- 347
+C+ +D C + C T S+ C C G+ G C + ++ C + +G+
Sbjct: 839 GSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGW--TGPLCNLPLSSCQKAALSQGID 896
Query: 348 ----CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ--APCRNYAGGY 509
C + G CV+ S+ C CP G+ +G+ C D ++ CQ A C GY
Sbjct: 897 VSSLCHNGGLCVDSGPSYFCHCPPGF----QGSLCQDHVNPCESRPCQNGATCMAQPSGY 952
Query: 510 RCDCPVG 530
C C G
Sbjct: 953 LCQCAPG 959
Score = 68.1 bits (159), Expect = 2e-11
Identities = 50/171 (29%), Positives = 69/171 (40%), Gaps = 5/171 (2%)
Frame = +3
Query: 33 CVCGPGYR-PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-RDV 206
CVC G+ P G C P C+ Y+C C TGY G C ++
Sbjct: 677 CVCDVGWTGPECEAELGG--CISAPCAHGGTCYPQPSGYNCTCPTGYT----GPTCSEEM 730
Query: 207 DECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGS 386
C C+ + G Y C+C + G C + C + G CVN G+
Sbjct: 731 TACHSGPCLNGGSCNPSPGGYYCTCPPSHT--GPQCQTSTDYCVSAPCFNGGTCVNRPGT 788
Query: 387 FRCVCPRGYRLDAEGARCVD--RDECAQTG-RCQAPCRNYAGGYRCDCPVG 530
F C+C G+ +G RC R CA + R +A C++ G RC CP G
Sbjct: 789 FSCLCAMGF----QGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTG 835
Score = 67.7 bits (158), Expect = 3e-11
Identities = 52/183 (28%), Positives = 74/183 (40%), Gaps = 14/183 (7%)
Frame = +3
Query: 30 RCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DV 206
RC+C GY G D CA +P P + C T S+ CLC G+ G C +
Sbjct: 829 RCLCPTGYT-GGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWT----GPLCNLPL 883
Query: 207 DECERD--------THTCQQ--ICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCP 353
C++ + C +C ++ SY C C G++ G C D +N C E C
Sbjct: 884 SSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLCQDHVNPC-ESRPCQ 940
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ--APCRNYAGGYRCDCPV 527
+ C+ + C C GY +G C + Q+ C C GG+ C CP
Sbjct: 941 NGATCMAQPSGYLCQCAPGY----DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPP 996
Query: 528 GTV 536
G V
Sbjct: 997 GFV 999
Score = 66.1 bits (154), Expect = 8e-11
Identities = 45/144 (31%), Positives = 66/144 (45%), Gaps = 7/144 (4%)
Frame = +3
Query: 120 LCHNTDGSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQ--ICSNTEGSYECSCEDG 290
LC ++ SY C C G++ G+ C+D V+ CE + CQ C Y C C G
Sbjct: 906 LCVDSGPSYFCHCPPGFQ----GSLCQDHVNPCE--SRPCQNGATCMAQPSGYLCQCAPG 959
Query: 291 YEKRGDACV-DINECHEEGVCPSPGRCVNLLGSFRCVCPRGY---RLDAEGARCVDRDEC 458
Y+ G C +++ C + C + G C G F C CP G+ R + + C+D+ C
Sbjct: 960 YD--GQNCSKELDACQSQP-CHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQ-PC 1015
Query: 459 AQTGRCQAPCRNYAGGYRCDCPVG 530
TG A C + A + C C G
Sbjct: 1016 HPTG--TAACHSLANAFYCQCLPG 1037
Score = 60.9 bits (141), Expect = 3e-09
Identities = 52/188 (27%), Positives = 74/188 (39%), Gaps = 20/188 (10%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGR-DECAVRP--PPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
G F C C PG+ G G DEC +P P CH+ ++ C C G+ G
Sbjct: 988 GGFHCACPPGF--VGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT----GQ 1041
Query: 192 NCR-DVDECERDTHTCQQICSNTEGS---YECSCEDGYE-----KRGDACVDINECHEEG 344
C ++D C C T GS + C C G+E R +C + CH G
Sbjct: 1042 WCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSC-GFHHCHHGG 1100
Query: 345 VC---PSPG-----RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYA 500
+C P PG C++ G C+ P + + C+ C++T P
Sbjct: 1101 LCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGP----- 1155
Query: 501 GGYRCDCP 524
G+RC CP
Sbjct: 1156 -GFRCSCP 1162
>BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 91.9 bits (218), Expect = 1e-18
Identities = 65/186 (34%), Positives = 88/186 (47%), Gaps = 12/186 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNT--DGSYDCLCRTGYELDE 182
++ +GSF C+C PG G D C +P D C GS CLC+ GY
Sbjct: 371 IDRVGSFSCLCPPG--RTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGY---- 424
Query: 183 DGANC-RDVDEC---ERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC-VDINECHEE 341
G C +D+DEC ++ C+ C NT GS+ C C GY G C D NEC +
Sbjct: 425 SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY--TGSRCEADHNECLSQ 482
Query: 342 GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRC--QAPCRNYAGGYR 512
C C++LL +F C+CP G EG C V+ +ECA + C A C + G++
Sbjct: 483 -PCHPGSTCLDLLATFHCLCPPG----LEGQLCEVETNECA-SAPCLNHADCHDLLNGFQ 536
Query: 513 CDCPVG 530
C C G
Sbjct: 537 CICLPG 542
Score = 83.8 bits (198), Expect = 4e-16
Identities = 57/179 (31%), Positives = 76/179 (42%), Gaps = 8/179 (4%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQL--CH-NTDGSYDCLCRTGYELDEDGAN 194
SF C C PG+ + D C P C + CH G C C G+ G
Sbjct: 100 SFLCTCLPGFTGERCQAKLEDPCP--PSFCSKRGRCHIQASGRPQCSCMPGWT----GEQ 153
Query: 195 CRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEE-GVCPSPGRC 368
C+ D C + +C T +C C G+E G AC D+NEC ++ G CP C
Sbjct: 154 CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFE--GHACERDVNECFQDPGPCPKGTSC 211
Query: 369 VNLLGSFRCVCP---RGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTV 536
N LGSF+C+CP G R + C R C+ G CQ + + C CP G +
Sbjct: 212 HNTLGSFQCLCPVGQEGPRCELRAGPCPPRG-CSNGGTCQLMPEKDSTFHLCLCPPGFI 269
Score = 82.2 bits (194), Expect = 1e-15
Identities = 61/182 (33%), Positives = 79/182 (43%), Gaps = 9/182 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N+ GSF CVC G+ D+C C + GS+ CLC G G
Sbjct: 334 NSAGSFHCVCVSGWGGTSCE-ENLDDCIAATCAPGSTCIDRVGSFSCLCPPG----RTGL 388
Query: 192 NCRDVDEC-ERDTHTCQQICSNT-EGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSP- 359
C D C + H Q +N GS C C+ GY G C D++EC PSP
Sbjct: 389 LCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS--GPTCHQDLDECLMAQQGPSPC 446
Query: 360 ---GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDEC-AQTGRCQAPCRNYAGGYRCDCP 524
G C+N GSF C+CP GY G+RC D +EC +Q + C + + C CP
Sbjct: 447 EHGGSCLNTPGSFNCLCPPGY----TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCP 502
Query: 525 VG 530
G
Sbjct: 503 PG 504
Score = 81.4 bits (192), Expect = 2e-15
Identities = 56/178 (31%), Positives = 79/178 (44%), Gaps = 4/178 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+NT GSF C+C PGY R +EC +P C + ++ CLC G E G
Sbjct: 453 LNTPGSFNCLCPPGY-TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLE----G 507
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
C + +EC C + ++C C G+ G C DI+EC C + G
Sbjct: 508 QLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFS--GTRCEEDIDEC-RSSPCANGG 564
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARC-VDRDEC-AQTGRCQAPCRNYAGGYRCDCPVG 530
+C + G+F C C G+ EG RC + DEC + A C + G + C CP G
Sbjct: 565 QCQDQPGAFHCKCLPGF----EGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSG 618
Score = 78.2 bits (184), Expect = 2e-14
Identities = 52/179 (29%), Positives = 80/179 (44%), Gaps = 4/179 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ + +F C+C PG V +ECA P CH+ + C+C G+ G
Sbjct: 491 LDLLATFHCLCPPGLEGQLCEVE-TNECASAPCLNHADCHDLLNGFQCICLPGFS----G 545
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
C D+DEC C + G++ C C G+E G C +++EC + CP
Sbjct: 546 TRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE--GPRCQTEVDECLSDP-CPVGA 602
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRCDCPVGT 533
C++L G+F C+CP G+ G C + CA CQ C++ C CP G+
Sbjct: 603 SCLDLPGAFFCLCPSGF----TGQLC-EVPLCA-PNLCQPKQICKDQKDKANCLCPDGS 655
Score = 70.9 bits (166), Expect = 3e-12
Identities = 60/191 (31%), Positives = 84/191 (43%), Gaps = 18/191 (9%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCD----------QLCHNTDGSYD-CLC 158
NT+GSF+C+C G G R C +R PC QL D ++ CLC
Sbjct: 213 NTLGSFQCLCPVGQE----GPR----CELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLC 264
Query: 159 RTGYELDEDGANCR-DVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACVDINE 329
G+ G +C + D C +H CQ C + +Y C C + + D D++E
Sbjct: 265 PPGFI----GPDCEVNPDNCV--SHQCQNGGTCQDGLDTYTCLCPETWTG-WDCSEDVDE 317
Query: 330 CHEEGV--CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DEC-AQTGRCQAPCRNY 497
C +G C + G C N GSF CVC G+ G C + D+C A T + C +
Sbjct: 318 CETQGPPHCRNGGTCQNSAGSFHCVCVSGW----GGTSCEENLDDCIAATCAPGSTCIDR 373
Query: 498 AGGYRCDCPVG 530
G + C CP G
Sbjct: 374 VGSFSCLCPPG 384
Score = 70.1 bits (164), Expect = 5e-12
Identities = 53/187 (28%), Positives = 80/187 (42%), Gaps = 13/187 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
VN G+F C+C G++ + R CA P C ++ CLC TGY G
Sbjct: 783 VNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGY----TG 838
Query: 189 ANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHE----EGV- 347
+C+ +D C + C T S+ C C G+ G C + ++ C + +G+
Sbjct: 839 GSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGW--TGPLCNLPLSSCQKAALSQGID 896
Query: 348 ----CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ--APCRNYAGGY 509
C + G CV+ S+ C CP G+ +G+ C D ++ CQ A C GY
Sbjct: 897 VSSLCHNGGLCVDSGPSYFCHCPPGF----QGSLCQDHVNPCESRPCQNGATCMAQPSGY 952
Query: 510 RCDCPVG 530
C C G
Sbjct: 953 LCQCAPG 959
Score = 68.1 bits (159), Expect = 2e-11
Identities = 50/171 (29%), Positives = 69/171 (40%), Gaps = 5/171 (2%)
Frame = +3
Query: 33 CVCGPGYR-PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-RDV 206
CVC G+ P G C P C+ Y+C C TGY G C ++
Sbjct: 677 CVCDVGWTGPECEAELGG--CISAPCAHGGTCYPQPSGYNCTCPTGYT----GPTCSEEM 730
Query: 207 DECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGS 386
C C+ + G Y C+C + G C + C + G CVN G+
Sbjct: 731 TACHSGPCLNGGSCNPSPGGYYCTCPPSHT--GPQCQTSTDYCVSAPCFNGGTCVNRPGT 788
Query: 387 FRCVCPRGYRLDAEGARCVD--RDECAQTG-RCQAPCRNYAGGYRCDCPVG 530
F C+C G+ +G RC R CA + R +A C++ G RC CP G
Sbjct: 789 FSCLCAMGF----QGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTG 835
Score = 67.7 bits (158), Expect = 3e-11
Identities = 52/183 (28%), Positives = 74/183 (40%), Gaps = 14/183 (7%)
Frame = +3
Query: 30 RCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DV 206
RC+C GY G D CA +P P + C T S+ CLC G+ G C +
Sbjct: 829 RCLCPTGYT-GGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWT----GPLCNLPL 883
Query: 207 DECERD--------THTCQQ--ICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCP 353
C++ + C +C ++ SY C C G++ G C D +N C E C
Sbjct: 884 SSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLCQDHVNPC-ESRPCQ 940
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ--APCRNYAGGYRCDCPV 527
+ C+ + C C GY +G C + Q+ C C GG+ C CP
Sbjct: 941 NGATCMAQPSGYLCQCAPGY----DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPP 996
Query: 528 GTV 536
G V
Sbjct: 997 GFV 999
Score = 66.1 bits (154), Expect = 8e-11
Identities = 45/144 (31%), Positives = 66/144 (45%), Gaps = 7/144 (4%)
Frame = +3
Query: 120 LCHNTDGSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQ--ICSNTEGSYECSCEDG 290
LC ++ SY C C G++ G+ C+D V+ CE + CQ C Y C C G
Sbjct: 906 LCVDSGPSYFCHCPPGFQ----GSLCQDHVNPCE--SRPCQNGATCMAQPSGYLCQCAPG 959
Query: 291 YEKRGDACV-DINECHEEGVCPSPGRCVNLLGSFRCVCPRGY---RLDAEGARCVDRDEC 458
Y+ G C +++ C + C + G C G F C CP G+ R + + C+D+ C
Sbjct: 960 YD--GQNCSKELDACQSQP-CHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQ-PC 1015
Query: 459 AQTGRCQAPCRNYAGGYRCDCPVG 530
TG A C + A + C C G
Sbjct: 1016 HPTG--TAACHSLANAFYCQCLPG 1037
Score = 60.9 bits (141), Expect = 3e-09
Identities = 52/188 (27%), Positives = 74/188 (39%), Gaps = 20/188 (10%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGR-DECAVRP--PPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
G F C C PG+ G G DEC +P P CH+ ++ C C G+ G
Sbjct: 988 GGFHCACPPGF--VGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT----GQ 1041
Query: 192 NCR-DVDECERDTHTCQQICSNTEGS---YECSCEDGYE-----KRGDACVDINECHEEG 344
C ++D C C T GS + C C G+E R +C + CH G
Sbjct: 1042 WCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSC-GFHHCHHGG 1100
Query: 345 VC---PSPG-----RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYA 500
+C P PG C++ G C+ P + + C+ C++T P
Sbjct: 1101 LCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGP----- 1155
Query: 501 GGYRCDCP 524
G+RC CP
Sbjct: 1156 -GFRCSCP 1162
>BC063815-1|AAH63815.1| 647|Homo sapiens NOTCH4 protein protein.
Length = 647
Score = 91.9 bits (218), Expect = 1e-18
Identities = 65/186 (34%), Positives = 88/186 (47%), Gaps = 12/186 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNT--DGSYDCLCRTGYELDE 182
++ +GSF C+C PG G D C +P D C GS CLC+ GY
Sbjct: 371 IDRVGSFSCLCPPG--RTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGY---- 424
Query: 183 DGANC-RDVDEC---ERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC-VDINECHEE 341
G C +D+DEC ++ C+ C NT GS+ C C GY G C D NEC +
Sbjct: 425 SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY--TGSRCEADHNECLSQ 482
Query: 342 GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRC--QAPCRNYAGGYR 512
C C++LL +F C+CP G EG C V+ +ECA + C A C + G++
Sbjct: 483 -PCHPGSTCLDLLATFHCLCPPG----LEGQLCEVETNECA-SAPCLNHADCHDLLNGFQ 536
Query: 513 CDCPVG 530
C C G
Sbjct: 537 CICLPG 542
Score = 83.8 bits (198), Expect = 4e-16
Identities = 57/179 (31%), Positives = 76/179 (42%), Gaps = 8/179 (4%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQL--CH-NTDGSYDCLCRTGYELDEDGAN 194
SF C C PG+ + D C P C + CH G C C G+ G
Sbjct: 100 SFLCTCLPGFTGERCQAKLEDPCP--PSFCSKRGRCHIQASGRPQCSCMPGWT----GEQ 153
Query: 195 CRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEE-GVCPSPGRC 368
C+ D C + +C T +C C G+E G AC D+NEC ++ G CP C
Sbjct: 154 CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFE--GHACERDVNECFQDPGPCPKGTSC 211
Query: 369 VNLLGSFRCVCP---RGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTV 536
N LGSF+C+CP G R + C R C+ G CQ + + C CP G +
Sbjct: 212 HNTLGSFQCLCPVGQEGPRCELRAGPCPPRG-CSNGGTCQLMPEKDSTFHLCLCPPGFI 269
Score = 82.2 bits (194), Expect = 1e-15
Identities = 61/182 (33%), Positives = 79/182 (43%), Gaps = 9/182 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N+ GSF CVC G+ D+C C + GS+ CLC G G
Sbjct: 334 NSAGSFHCVCVSGWGGTSCE-ENLDDCIAATCAPGSTCIDRVGSFSCLCPPG----RTGL 388
Query: 192 NCRDVDEC-ERDTHTCQQICSNT-EGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSP- 359
C D C + H Q +N GS C C+ GY G C D++EC PSP
Sbjct: 389 LCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS--GPTCHQDLDECLMAQQGPSPC 446
Query: 360 ---GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDEC-AQTGRCQAPCRNYAGGYRCDCP 524
G C+N GSF C+CP GY G+RC D +EC +Q + C + + C CP
Sbjct: 447 EHGGSCLNTPGSFNCLCPPGY----TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCP 502
Query: 525 VG 530
G
Sbjct: 503 PG 504
Score = 81.4 bits (192), Expect = 2e-15
Identities = 56/178 (31%), Positives = 79/178 (44%), Gaps = 4/178 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+NT GSF C+C PGY R +EC +P C + ++ CLC G E G
Sbjct: 453 LNTPGSFNCLCPPGY-TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLE----G 507
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
C + +EC C + ++C C G+ G C DI+EC C + G
Sbjct: 508 QLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFS--GTRCEEDIDEC-RSSPCANGG 564
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARC-VDRDEC-AQTGRCQAPCRNYAGGYRCDCPVG 530
+C + G+F C C G+ EG RC + DEC + A C + G + C CP G
Sbjct: 565 QCQDQPGAFHCKCLPGF----EGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSG 618
Score = 75.8 bits (178), Expect = 1e-13
Identities = 41/137 (29%), Positives = 65/137 (47%), Gaps = 2/137 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ + +F C+C PG V +ECA P CH+ + C+C G+ G
Sbjct: 491 LDLLATFHCLCPPGLEGQLCEVE-TNECASAPCLNHADCHDLLNGFQCICLPGFS----G 545
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
C D+DEC C + G++ C C G+E G C +++EC + CP
Sbjct: 546 TRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE--GPRCQTEVDECLSDP-CPVGA 602
Query: 363 RCVNLLGSFRCVCPRGY 413
C++L G+F C+CP G+
Sbjct: 603 SCLDLPGAFFCLCPSGF 619
Score = 70.9 bits (166), Expect = 3e-12
Identities = 60/191 (31%), Positives = 84/191 (43%), Gaps = 18/191 (9%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCD----------QLCHNTDGSYD-CLC 158
NT+GSF+C+C G G R C +R PC QL D ++ CLC
Sbjct: 213 NTLGSFQCLCPVGQE----GPR----CELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLC 264
Query: 159 RTGYELDEDGANCR-DVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACVDINE 329
G+ G +C + D C +H CQ C + +Y C C + + D D++E
Sbjct: 265 PPGFI----GPDCEVNPDNCV--SHQCQNGGTCQDGLDTYTCLCPETWTG-WDCSEDVDE 317
Query: 330 CHEEGV--CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DEC-AQTGRCQAPCRNY 497
C +G C + G C N GSF CVC G+ G C + D+C A T + C +
Sbjct: 318 CETQGPPHCRNGGTCQNSAGSFHCVCVSGW----GGTSCEENLDDCIAATCAPGSTCIDR 373
Query: 498 AGGYRCDCPVG 530
G + C CP G
Sbjct: 374 VGSFSCLCPPG 384
>AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 91.9 bits (218), Expect = 1e-18
Identities = 65/186 (34%), Positives = 88/186 (47%), Gaps = 12/186 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNT--DGSYDCLCRTGYELDE 182
++ +GSF C+C PG G D C +P D C GS CLC+ GY
Sbjct: 371 IDRVGSFSCLCPPG--RTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGY---- 424
Query: 183 DGANC-RDVDEC---ERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC-VDINECHEE 341
G C +D+DEC ++ C+ C NT GS+ C C GY G C D NEC +
Sbjct: 425 SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY--TGSRCEADHNECLSQ 482
Query: 342 GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRC--QAPCRNYAGGYR 512
C C++LL +F C+CP G EG C V+ +ECA + C A C + G++
Sbjct: 483 -PCHPGSTCLDLLATFHCLCPPG----LEGQLCEVETNECA-SAPCLNHADCHDLLNGFQ 536
Query: 513 CDCPVG 530
C C G
Sbjct: 537 CICLPG 542
Score = 83.8 bits (198), Expect = 4e-16
Identities = 57/179 (31%), Positives = 76/179 (42%), Gaps = 8/179 (4%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQL--CH-NTDGSYDCLCRTGYELDEDGAN 194
SF C C PG+ + D C P C + CH G C C G+ G
Sbjct: 100 SFLCTCLPGFTGERCQAKLEDPCP--PSFCSKRGRCHIQASGRPQCSCMPGWT----GEQ 153
Query: 195 CRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEE-GVCPSPGRC 368
C+ D C + +C T +C C G+E G AC D+NEC ++ G CP C
Sbjct: 154 CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFE--GHACERDVNECFQDPGPCPKGTSC 211
Query: 369 VNLLGSFRCVCP---RGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTV 536
N LGSF+C+CP G R + C R C+ G CQ + + C CP G +
Sbjct: 212 HNTLGSFQCLCPVGQEGPRCELRAGPCPPRG-CSNGGTCQLMPEKDSTFHLCLCPPGFI 269
Score = 82.2 bits (194), Expect = 1e-15
Identities = 61/182 (33%), Positives = 79/182 (43%), Gaps = 9/182 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N+ GSF CVC G+ D+C C + GS+ CLC G G
Sbjct: 334 NSAGSFHCVCVSGWGGTSCE-ENLDDCIAATCAPGSTCIDRVGSFSCLCPPG----RTGL 388
Query: 192 NCRDVDEC-ERDTHTCQQICSNT-EGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSP- 359
C D C + H Q +N GS C C+ GY G C D++EC PSP
Sbjct: 389 LCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS--GPTCHQDLDECLMAQQGPSPC 446
Query: 360 ---GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDEC-AQTGRCQAPCRNYAGGYRCDCP 524
G C+N GSF C+CP GY G+RC D +EC +Q + C + + C CP
Sbjct: 447 EHGGSCLNTPGSFNCLCPPGY----TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCP 502
Query: 525 VG 530
G
Sbjct: 503 PG 504
Score = 81.4 bits (192), Expect = 2e-15
Identities = 56/178 (31%), Positives = 79/178 (44%), Gaps = 4/178 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+NT GSF C+C PGY R +EC +P C + ++ CLC G E G
Sbjct: 453 LNTPGSFNCLCPPGY-TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLE----G 507
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
C + +EC C + ++C C G+ G C DI+EC C + G
Sbjct: 508 QLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFS--GTRCEEDIDEC-RSSPCANGG 564
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARC-VDRDEC-AQTGRCQAPCRNYAGGYRCDCPVG 530
+C + G+F C C G+ EG RC + DEC + A C + G + C CP G
Sbjct: 565 QCQDQPGAFHCKCLPGF----EGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSG 618
Score = 78.2 bits (184), Expect = 2e-14
Identities = 52/179 (29%), Positives = 80/179 (44%), Gaps = 4/179 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ + +F C+C PG V +ECA P CH+ + C+C G+ G
Sbjct: 491 LDLLATFHCLCPPGLEGQLCEVE-TNECASAPCLNHADCHDLLNGFQCICLPGFS----G 545
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
C D+DEC C + G++ C C G+E G C +++EC + CP
Sbjct: 546 TRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE--GPRCQTEVDECLSDP-CPVGA 602
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRCDCPVGT 533
C++L G+F C+CP G+ G C + CA CQ C++ C CP G+
Sbjct: 603 SCLDLPGAFFCLCPSGF----TGQLC-EVPLCA-PNLCQPKQICKDQKDKANCLCPDGS 655
Score = 70.9 bits (166), Expect = 3e-12
Identities = 60/191 (31%), Positives = 84/191 (43%), Gaps = 18/191 (9%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCD----------QLCHNTDGSYD-CLC 158
NT+GSF+C+C G G R C +R PC QL D ++ CLC
Sbjct: 213 NTLGSFQCLCPVGQE----GPR----CELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLC 264
Query: 159 RTGYELDEDGANCR-DVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACVDINE 329
G+ G +C + D C +H CQ C + +Y C C + + D D++E
Sbjct: 265 PPGFI----GPDCEVNPDNCV--SHQCQNGGTCQDGLDTYTCLCPETWTG-WDCSEDVDE 317
Query: 330 CHEEGV--CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DEC-AQTGRCQAPCRNY 497
C +G C + G C N GSF CVC G+ G C + D+C A T + C +
Sbjct: 318 CETQGPPHCRNGGTCQNSAGSFHCVCVSGW----GGTSCEENLDDCIAATCAPGSTCIDR 373
Query: 498 AGGYRCDCPVG 530
G + C CP G
Sbjct: 374 VGSFSCLCPPG 384
Score = 66.5 bits (155), Expect = 6e-11
Identities = 52/187 (27%), Positives = 79/187 (42%), Gaps = 13/187 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
VN G+F C+C G++ + R CA P C ++ CLC T Y G
Sbjct: 783 VNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTVY----TG 838
Query: 189 ANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHE----EGV- 347
+C+ +D C + C T S+ C C G+ G C + ++ C + +G+
Sbjct: 839 GSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGW--TGPLCNLPLSSCQKAALSQGID 896
Query: 348 ----CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ--APCRNYAGGY 509
C + G CV+ S+ C CP G+ +G+ C D ++ CQ A C GY
Sbjct: 897 VSSLCHNGGLCVDSGPSYFCHCPPGF----QGSLCQDHVNPCESRPCQNGATCMAQPSGY 952
Query: 510 RCDCPVG 530
C C G
Sbjct: 953 LCQCAPG 959
Score = 66.1 bits (154), Expect = 8e-11
Identities = 45/144 (31%), Positives = 66/144 (45%), Gaps = 7/144 (4%)
Frame = +3
Query: 120 LCHNTDGSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQ--ICSNTEGSYECSCEDG 290
LC ++ SY C C G++ G+ C+D V+ CE + CQ C Y C C G
Sbjct: 906 LCVDSGPSYFCHCPPGFQ----GSLCQDHVNPCE--SRPCQNGATCMAQPSGYLCQCAPG 959
Query: 291 YEKRGDACV-DINECHEEGVCPSPGRCVNLLGSFRCVCPRGY---RLDAEGARCVDRDEC 458
Y+ G C +++ C + C + G C G F C CP G+ R + + C+D+ C
Sbjct: 960 YD--GQNCSKELDACQSQP-CHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQ-PC 1015
Query: 459 AQTGRCQAPCRNYAGGYRCDCPVG 530
TG A C + A + C C G
Sbjct: 1016 HPTG--TAACHSLANAFYCQCLPG 1037
Score = 65.7 bits (153), Expect = 1e-10
Identities = 49/169 (28%), Positives = 68/169 (40%), Gaps = 5/169 (2%)
Frame = +3
Query: 33 CVCGPGYR-PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-RDV 206
CVC G+ P G C P C+ Y+C C TGY G C ++
Sbjct: 677 CVCDVGWTGPECEAELGG--CISAPCAHGGTCYPQPSGYNCTCPTGYT----GPTCSEEM 730
Query: 207 DECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGS 386
C C+ + G Y C+C + G C + C + G CVN G+
Sbjct: 731 TACHSGPCLNGGSCNPSPGGYYCTCPPSHT--GPQCQTSTDYCVSAPCFNGGTCVNRPGT 788
Query: 387 FRCVCPRGYRLDAEGARCVD--RDECAQTG-RCQAPCRNYAGGYRCDCP 524
F C+C G+ +G RC R CA + R +A C++ G RC CP
Sbjct: 789 FSCLCAMGF----QGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCP 833
Score = 64.5 bits (150), Expect = 2e-10
Identities = 51/183 (27%), Positives = 73/183 (39%), Gaps = 14/183 (7%)
Frame = +3
Query: 30 RCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DV 206
RC+C P G D CA +P P + C T S+ CLC G+ G C +
Sbjct: 829 RCLC-PTVYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWT----GPLCNLPL 883
Query: 207 DECERD--------THTCQQ--ICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCP 353
C++ + C +C ++ SY C C G++ G C D +N C E C
Sbjct: 884 SSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLCQDHVNPC-ESRPCQ 940
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ--APCRNYAGGYRCDCPV 527
+ C+ + C C GY +G C + Q+ C C GG+ C CP
Sbjct: 941 NGATCMAQPSGYLCQCAPGY----DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPP 996
Query: 528 GTV 536
G V
Sbjct: 997 GFV 999
Score = 61.3 bits (142), Expect = 2e-09
Identities = 56/196 (28%), Positives = 78/196 (39%), Gaps = 25/196 (12%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
+ F+C+C PG+ R DEC P C + G++ C C G+E G C
Sbjct: 532 LNGFQCICLPGFSGT-RCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE----GPRC 586
Query: 198 R-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDI---NECHEEGVCPSPG 362
+ +VDEC D C + G++ C C G+ G C V + N C + +C
Sbjct: 587 QTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFT--GQLCEVPLCAPNLCQPKQICKDQK 644
Query: 363 RCVNLL---GSFRCVCPRG----YRLDAEGARCV-----DRDEC-AQTGRC-QAPCRN-- 494
N L GS C P + + + CV EC A+ G C APC +
Sbjct: 645 DKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGG 704
Query: 495 ----YAGGYRCDCPVG 530
GY C CP G
Sbjct: 705 TCYPQPSGYNCTCPTG 720
Score = 60.9 bits (141), Expect = 3e-09
Identities = 52/188 (27%), Positives = 74/188 (39%), Gaps = 20/188 (10%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGR-DECAVRP--PPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
G F C C PG+ G G DEC +P P CH+ ++ C C G+ G
Sbjct: 988 GGFHCACPPGF--VGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT----GQ 1041
Query: 192 NCR-DVDECERDTHTCQQICSNTEGS---YECSCEDGYE-----KRGDACVDINECHEEG 344
C ++D C C T GS + C C G+E R +C + CH G
Sbjct: 1042 WCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSC-GFHHCHHGG 1100
Query: 345 VC---PSPG-----RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYA 500
+C P PG C++ G C+ P + + C+ C++T P
Sbjct: 1101 LCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGP----- 1155
Query: 501 GGYRCDCP 524
G+RC CP
Sbjct: 1156 -GFRCSCP 1162
>AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 91.9 bits (218), Expect = 1e-18
Identities = 65/186 (34%), Positives = 88/186 (47%), Gaps = 12/186 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNT--DGSYDCLCRTGYELDE 182
++ +GSF C+C PG G D C +P D C GS CLC+ GY
Sbjct: 371 IDRVGSFSCLCPPG--RTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGY---- 424
Query: 183 DGANC-RDVDEC---ERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC-VDINECHEE 341
G C +D+DEC ++ C+ C NT GS+ C C GY G C D NEC +
Sbjct: 425 SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY--TGSRCEADHNECLSQ 482
Query: 342 GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRC--QAPCRNYAGGYR 512
C C++LL +F C+CP G EG C V+ +ECA + C A C + G++
Sbjct: 483 -PCHPGSTCLDLLATFHCLCPPG----LEGQLCEVETNECA-SAPCLNHADCHDLLNGFQ 536
Query: 513 CDCPVG 530
C C G
Sbjct: 537 CICLPG 542
Score = 83.8 bits (198), Expect = 4e-16
Identities = 57/179 (31%), Positives = 76/179 (42%), Gaps = 8/179 (4%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQL--CH-NTDGSYDCLCRTGYELDEDGAN 194
SF C C PG+ + D C P C + CH G C C G+ G
Sbjct: 100 SFLCTCLPGFTGERCQAKLEDPCP--PSFCSKRGRCHIQASGRPQCSCMPGWT----GEQ 153
Query: 195 CRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEE-GVCPSPGRC 368
C+ D C + +C T +C C G+E G AC D+NEC ++ G CP C
Sbjct: 154 CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFE--GHACERDVNECFQDPGPCPKGTSC 211
Query: 369 VNLLGSFRCVCP---RGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTV 536
N LGSF+C+CP G R + C R C+ G CQ + + C CP G +
Sbjct: 212 HNTLGSFQCLCPVGQEGPRCELRAGPCPPRG-CSNGGTCQLMPEKDSTFHLCLCPPGFI 269
Score = 82.2 bits (194), Expect = 1e-15
Identities = 61/182 (33%), Positives = 79/182 (43%), Gaps = 9/182 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N+ GSF CVC G+ D+C C + GS+ CLC G G
Sbjct: 334 NSAGSFHCVCVSGWGGTSCE-ENLDDCIAATCAPGSTCIDRVGSFSCLCPPG----RTGL 388
Query: 192 NCRDVDEC-ERDTHTCQQICSNT-EGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSP- 359
C D C + H Q +N GS C C+ GY G C D++EC PSP
Sbjct: 389 LCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS--GPTCHQDLDECLMAQQGPSPC 446
Query: 360 ---GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDEC-AQTGRCQAPCRNYAGGYRCDCP 524
G C+N GSF C+CP GY G+RC D +EC +Q + C + + C CP
Sbjct: 447 EHGGSCLNTPGSFNCLCPPGY----TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCP 502
Query: 525 VG 530
G
Sbjct: 503 PG 504
Score = 81.4 bits (192), Expect = 2e-15
Identities = 56/178 (31%), Positives = 79/178 (44%), Gaps = 4/178 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+NT GSF C+C PGY R +EC +P C + ++ CLC G E G
Sbjct: 453 LNTPGSFNCLCPPGY-TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLE----G 507
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
C + +EC C + ++C C G+ G C DI+EC C + G
Sbjct: 508 QLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFS--GTRCEEDIDEC-RSSPCANGG 564
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARC-VDRDEC-AQTGRCQAPCRNYAGGYRCDCPVG 530
+C + G+F C C G+ EG RC + DEC + A C + G + C CP G
Sbjct: 565 QCQDQPGAFHCKCLPGF----EGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSG 618
Score = 78.2 bits (184), Expect = 2e-14
Identities = 52/179 (29%), Positives = 80/179 (44%), Gaps = 4/179 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ + +F C+C PG V +ECA P CH+ + C+C G+ G
Sbjct: 491 LDLLATFHCLCPPGLEGQLCEVE-TNECASAPCLNHADCHDLLNGFQCICLPGFS----G 545
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
C D+DEC C + G++ C C G+E G C +++EC + CP
Sbjct: 546 TRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE--GPRCQTEVDECLSDP-CPVGA 602
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRCDCPVGT 533
C++L G+F C+CP G+ G C + CA CQ C++ C CP G+
Sbjct: 603 SCLDLPGAFFCLCPSGF----TGQLC-EVPLCA-PNLCQPKQICKDQKDKANCLCPDGS 655
Score = 70.9 bits (166), Expect = 3e-12
Identities = 60/191 (31%), Positives = 84/191 (43%), Gaps = 18/191 (9%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCD----------QLCHNTDGSYD-CLC 158
NT+GSF+C+C G G R C +R PC QL D ++ CLC
Sbjct: 213 NTLGSFQCLCPVGQE----GPR----CELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLC 264
Query: 159 RTGYELDEDGANCR-DVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACVDINE 329
G+ G +C + D C +H CQ C + +Y C C + + D D++E
Sbjct: 265 PPGFI----GPDCEVNPDNCV--SHQCQNGGTCQDGLDTYTCLCPETWTG-WDCSEDVDE 317
Query: 330 CHEEGV--CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DEC-AQTGRCQAPCRNY 497
C +G C + G C N GSF CVC G+ G C + D+C A T + C +
Sbjct: 318 CETQGPPHCRNGGTCQNSAGSFHCVCVSGW----GGTSCEENLDDCIAATCAPGSTCIDR 373
Query: 498 AGGYRCDCPVG 530
G + C CP G
Sbjct: 374 VGSFSCLCPPG 384
Score = 66.5 bits (155), Expect = 6e-11
Identities = 52/187 (27%), Positives = 79/187 (42%), Gaps = 13/187 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
VN G+F C+C G++ + R CA P C ++ CLC T Y G
Sbjct: 783 VNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTVY----TG 838
Query: 189 ANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHE----EGV- 347
+C+ +D C + C T S+ C C G+ G C + ++ C + +G+
Sbjct: 839 GSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGW--TGPLCNLPLSSCQKAALSQGID 896
Query: 348 ----CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ--APCRNYAGGY 509
C + G CV+ S+ C CP G+ +G+ C D ++ CQ A C GY
Sbjct: 897 VSSLCHNGGLCVDSGPSYFCHCPPGF----QGSLCQDHVNPCESRPCQNGATCMAQPSGY 952
Query: 510 RCDCPVG 530
C C G
Sbjct: 953 LCQCAPG 959
Score = 66.1 bits (154), Expect = 8e-11
Identities = 45/144 (31%), Positives = 66/144 (45%), Gaps = 7/144 (4%)
Frame = +3
Query: 120 LCHNTDGSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQ--ICSNTEGSYECSCEDG 290
LC ++ SY C C G++ G+ C+D V+ CE + CQ C Y C C G
Sbjct: 906 LCVDSGPSYFCHCPPGFQ----GSLCQDHVNPCE--SRPCQNGATCMAQPSGYLCQCAPG 959
Query: 291 YEKRGDACV-DINECHEEGVCPSPGRCVNLLGSFRCVCPRGY---RLDAEGARCVDRDEC 458
Y+ G C +++ C + C + G C G F C CP G+ R + + C+D+ C
Sbjct: 960 YD--GQNCSKELDACQSQP-CHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQ-PC 1015
Query: 459 AQTGRCQAPCRNYAGGYRCDCPVG 530
TG A C + A + C C G
Sbjct: 1016 HPTG--TAACHSLANAFYCQCLPG 1037
Score = 65.7 bits (153), Expect = 1e-10
Identities = 49/169 (28%), Positives = 68/169 (40%), Gaps = 5/169 (2%)
Frame = +3
Query: 33 CVCGPGYR-PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-RDV 206
CVC G+ P G C P C+ Y+C C TGY G C ++
Sbjct: 677 CVCDVGWTGPECEAELGG--CISAPCAHGGTCYPQPSGYNCTCPTGYT----GPTCSEEM 730
Query: 207 DECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGS 386
C C+ + G Y C+C + G C + C + G CVN G+
Sbjct: 731 TACHSGPCLNGGSCNPSPGGYYCTCPPSHT--GPQCQTSTDYCVSAPCFNGGTCVNRPGT 788
Query: 387 FRCVCPRGYRLDAEGARCVD--RDECAQTG-RCQAPCRNYAGGYRCDCP 524
F C+C G+ +G RC R CA + R +A C++ G RC CP
Sbjct: 789 FSCLCAMGF----QGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCP 833
Score = 64.5 bits (150), Expect = 2e-10
Identities = 51/183 (27%), Positives = 73/183 (39%), Gaps = 14/183 (7%)
Frame = +3
Query: 30 RCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DV 206
RC+C P G D CA +P P + C T S+ CLC G+ G C +
Sbjct: 829 RCLC-PTVYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWT----GPLCNLPL 883
Query: 207 DECERD--------THTCQQ--ICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCP 353
C++ + C +C ++ SY C C G++ G C D +N C E C
Sbjct: 884 SSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLCQDHVNPC-ESRPCQ 940
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ--APCRNYAGGYRCDCPV 527
+ C+ + C C GY +G C + Q+ C C GG+ C CP
Sbjct: 941 NGATCMAQPSGYLCQCAPGY----DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPP 996
Query: 528 GTV 536
G V
Sbjct: 997 GFV 999
Score = 61.3 bits (142), Expect = 2e-09
Identities = 56/196 (28%), Positives = 78/196 (39%), Gaps = 25/196 (12%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
+ F+C+C PG+ R DEC P C + G++ C C G+E G C
Sbjct: 532 LNGFQCICLPGFSGT-RCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE----GPRC 586
Query: 198 R-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDI---NECHEEGVCPSPG 362
+ +VDEC D C + G++ C C G+ G C V + N C + +C
Sbjct: 587 QTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFT--GQLCEVPLCAPNLCQPKQICKDQK 644
Query: 363 RCVNLL---GSFRCVCPRG----YRLDAEGARCV-----DRDEC-AQTGRC-QAPCRN-- 494
N L GS C P + + + CV EC A+ G C APC +
Sbjct: 645 DKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGG 704
Query: 495 ----YAGGYRCDCPVG 530
GY C CP G
Sbjct: 705 TCYPQPSGYNCTCPTG 720
Score = 60.9 bits (141), Expect = 3e-09
Identities = 52/188 (27%), Positives = 74/188 (39%), Gaps = 20/188 (10%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGR-DECAVRP--PPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
G F C C PG+ G G DEC +P P CH+ ++ C C G+ G
Sbjct: 988 GGFHCACPPGF--VGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT----GQ 1041
Query: 192 NCR-DVDECERDTHTCQQICSNTEGS---YECSCEDGYE-----KRGDACVDINECHEEG 344
C ++D C C T GS + C C G+E R +C + CH G
Sbjct: 1042 WCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSC-GFHHCHHGG 1100
Query: 345 VC---PSPG-----RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYA 500
+C P PG C++ G C+ P + + C+ C++T P
Sbjct: 1101 LCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGP----- 1155
Query: 501 GGYRCDCP 524
G+RC CP
Sbjct: 1156 -GFRCSCP 1162
>AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 91.9 bits (218), Expect = 1e-18
Identities = 65/186 (34%), Positives = 88/186 (47%), Gaps = 12/186 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNT--DGSYDCLCRTGYELDE 182
++ +GSF C+C PG G D C +P D C GS CLC+ GY
Sbjct: 371 IDRVGSFSCLCPPG--RTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGY---- 424
Query: 183 DGANC-RDVDEC---ERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC-VDINECHEE 341
G C +D+DEC ++ C+ C NT GS+ C C GY G C D NEC +
Sbjct: 425 SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY--TGSRCEADHNECLSQ 482
Query: 342 GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRC--QAPCRNYAGGYR 512
C C++LL +F C+CP G EG C V+ +ECA + C A C + G++
Sbjct: 483 -PCHPGSTCLDLLATFHCLCPPG----LEGQLCEVETNECA-SAPCLNHADCHDLLNGFQ 536
Query: 513 CDCPVG 530
C C G
Sbjct: 537 CICLPG 542
Score = 83.8 bits (198), Expect = 4e-16
Identities = 57/179 (31%), Positives = 76/179 (42%), Gaps = 8/179 (4%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQL--CH-NTDGSYDCLCRTGYELDEDGAN 194
SF C C PG+ + D C P C + CH G C C G+ G
Sbjct: 100 SFLCTCLPGFTGERCQAKLEDPCP--PSFCSKRGRCHIQASGRPQCSCMPGWT----GEQ 153
Query: 195 CRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEE-GVCPSPGRC 368
C+ D C + +C T +C C G+E G AC D+NEC ++ G CP C
Sbjct: 154 CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFE--GHACERDVNECFQDPGPCPKGTSC 211
Query: 369 VNLLGSFRCVCP---RGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTV 536
N LGSF+C+CP G R + C R C+ G CQ + + C CP G +
Sbjct: 212 HNTLGSFQCLCPVGQEGPRCELRAGPCPPRG-CSNGGTCQLMPEKDSTFHLCLCPPGFI 269
Score = 82.2 bits (194), Expect = 1e-15
Identities = 61/182 (33%), Positives = 79/182 (43%), Gaps = 9/182 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N+ GSF CVC G+ D+C C + GS+ CLC G G
Sbjct: 334 NSAGSFHCVCVSGWGGTSCE-ENLDDCIAATCAPGSTCIDRVGSFSCLCPPG----RTGL 388
Query: 192 NCRDVDEC-ERDTHTCQQICSNT-EGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSP- 359
C D C + H Q +N GS C C+ GY G C D++EC PSP
Sbjct: 389 LCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS--GPTCHQDLDECLMAQQGPSPC 446
Query: 360 ---GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDEC-AQTGRCQAPCRNYAGGYRCDCP 524
G C+N GSF C+CP GY G+RC D +EC +Q + C + + C CP
Sbjct: 447 EHGGSCLNTPGSFNCLCPPGY----TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCP 502
Query: 525 VG 530
G
Sbjct: 503 PG 504
Score = 81.4 bits (192), Expect = 2e-15
Identities = 56/178 (31%), Positives = 79/178 (44%), Gaps = 4/178 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+NT GSF C+C PGY R +EC +P C + ++ CLC G E G
Sbjct: 453 LNTPGSFNCLCPPGY-TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLE----G 507
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
C + +EC C + ++C C G+ G C DI+EC C + G
Sbjct: 508 QLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFS--GTRCEEDIDEC-RSSPCANGG 564
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARC-VDRDEC-AQTGRCQAPCRNYAGGYRCDCPVG 530
+C + G+F C C G+ EG RC + DEC + A C + G + C CP G
Sbjct: 565 QCQDQPGAFHCKCLPGF----EGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSG 618
Score = 78.2 bits (184), Expect = 2e-14
Identities = 52/179 (29%), Positives = 80/179 (44%), Gaps = 4/179 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ + +F C+C PG V +ECA P CH+ + C+C G+ G
Sbjct: 491 LDLLATFHCLCPPGLEGQLCEVE-TNECASAPCLNHADCHDLLNGFQCICLPGFS----G 545
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
C D+DEC C + G++ C C G+E G C +++EC + CP
Sbjct: 546 TRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE--GPRCQTEVDECLSDP-CPVGA 602
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRCDCPVGT 533
C++L G+F C+CP G+ G C + CA CQ C++ C CP G+
Sbjct: 603 SCLDLPGAFFCLCPSGF----TGQLC-EVPLCA-PNLCQPKQICKDQKDKANCLCPDGS 655
Score = 70.9 bits (166), Expect = 3e-12
Identities = 60/191 (31%), Positives = 84/191 (43%), Gaps = 18/191 (9%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCD----------QLCHNTDGSYD-CLC 158
NT+GSF+C+C G G R C +R PC QL D ++ CLC
Sbjct: 213 NTLGSFQCLCPVGQE----GPR----CELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLC 264
Query: 159 RTGYELDEDGANCR-DVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACVDINE 329
G+ G +C + D C +H CQ C + +Y C C + + D D++E
Sbjct: 265 PPGFI----GPDCEVNPDNCV--SHQCQNGGTCQDGLDTYTCLCPETWTG-WDCSEDVDE 317
Query: 330 CHEEGV--CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DEC-AQTGRCQAPCRNY 497
C +G C + G C N GSF CVC G+ G C + D+C A T + C +
Sbjct: 318 CETQGPPHCRNGGTCQNSAGSFHCVCVSGW----GGTSCEENLDDCIAATCAPGSTCIDR 373
Query: 498 AGGYRCDCPVG 530
G + C CP G
Sbjct: 374 VGSFSCLCPPG 384
Score = 70.1 bits (164), Expect = 5e-12
Identities = 53/187 (28%), Positives = 80/187 (42%), Gaps = 13/187 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
VN G+F C+C G++ + R CA P C ++ CLC TGY G
Sbjct: 783 VNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGY----TG 838
Query: 189 ANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHE----EGV- 347
+C+ +D C + C T S+ C C G+ G C + ++ C + +G+
Sbjct: 839 GSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGW--TGPLCNLPLSSCQKAALSQGID 896
Query: 348 ----CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ--APCRNYAGGY 509
C + G CV+ S+ C CP G+ +G+ C D ++ CQ A C GY
Sbjct: 897 VSSLCHNGGLCVDSGPSYFCHCPPGF----QGSLCQDHVNPCESRPCQNGATCMAQPSGY 952
Query: 510 RCDCPVG 530
C C G
Sbjct: 953 LCQCAPG 959
Score = 68.1 bits (159), Expect = 2e-11
Identities = 50/171 (29%), Positives = 69/171 (40%), Gaps = 5/171 (2%)
Frame = +3
Query: 33 CVCGPGYR-PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-RDV 206
CVC G+ P G C P C+ Y+C C TGY G C ++
Sbjct: 677 CVCDVGWTGPECEAELGG--CISAPCAHGGTCYPQPSGYNCTCPTGYT----GPTCSEEM 730
Query: 207 DECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGS 386
C C+ + G Y C+C + G C + C + G CVN G+
Sbjct: 731 TACHSGPCLNGGSCNPSPGGYYCTCPPSHT--GPQCQTSTDYCVSAPCFNGGTCVNRPGT 788
Query: 387 FRCVCPRGYRLDAEGARCVD--RDECAQTG-RCQAPCRNYAGGYRCDCPVG 530
F C+C G+ +G RC R CA + R +A C++ G RC CP G
Sbjct: 789 FSCLCAMGF----QGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTG 835
Score = 67.7 bits (158), Expect = 3e-11
Identities = 52/183 (28%), Positives = 74/183 (40%), Gaps = 14/183 (7%)
Frame = +3
Query: 30 RCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DV 206
RC+C GY G D CA +P P + C T S+ CLC G+ G C +
Sbjct: 829 RCLCPTGYT-GGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWT----GPLCNLPL 883
Query: 207 DECERD--------THTCQQ--ICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCP 353
C++ + C +C ++ SY C C G++ G C D +N C E C
Sbjct: 884 SSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLCQDHVNPC-ESRPCQ 940
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ--APCRNYAGGYRCDCPV 527
+ C+ + C C GY +G C + Q+ C C GG+ C CP
Sbjct: 941 NGATCMAQPSGYLCQCAPGY----DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPP 996
Query: 528 GTV 536
G V
Sbjct: 997 GFV 999
Score = 66.1 bits (154), Expect = 8e-11
Identities = 45/144 (31%), Positives = 66/144 (45%), Gaps = 7/144 (4%)
Frame = +3
Query: 120 LCHNTDGSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQ--ICSNTEGSYECSCEDG 290
LC ++ SY C C G++ G+ C+D V+ CE + CQ C Y C C G
Sbjct: 906 LCVDSGPSYFCHCPPGFQ----GSLCQDHVNPCE--SRPCQNGATCMAQPSGYLCQCAPG 959
Query: 291 YEKRGDACV-DINECHEEGVCPSPGRCVNLLGSFRCVCPRGY---RLDAEGARCVDRDEC 458
Y+ G C +++ C + C + G C G F C CP G+ R + + C+D+ C
Sbjct: 960 YD--GQNCSKELDACQSQP-CHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQ-PC 1015
Query: 459 AQTGRCQAPCRNYAGGYRCDCPVG 530
TG A C + A + C C G
Sbjct: 1016 HPTG--TAACHSLANAFYCQCLPG 1037
Score = 60.9 bits (141), Expect = 3e-09
Identities = 52/188 (27%), Positives = 74/188 (39%), Gaps = 20/188 (10%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGR-DECAVRP--PPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
G F C C PG+ G G DEC +P P CH+ ++ C C G+ G
Sbjct: 988 GGFHCACPPGF--VGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT----GQ 1041
Query: 192 NCR-DVDECERDTHTCQQICSNTEGS---YECSCEDGYE-----KRGDACVDINECHEEG 344
C ++D C C T GS + C C G+E R +C + CH G
Sbjct: 1042 WCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSC-GFHHCHHGG 1100
Query: 345 VC---PSPG-----RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYA 500
+C P PG C++ G C+ P + + C+ C++T P
Sbjct: 1101 LCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGP----- 1155
Query: 501 GGYRCDCP 524
G+RC CP
Sbjct: 1156 -GFRCSCP 1162
>AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2005
Score = 91.9 bits (218), Expect = 1e-18
Identities = 65/186 (34%), Positives = 88/186 (47%), Gaps = 12/186 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNT--DGSYDCLCRTGYELDE 182
++ +GSF C+C PG G D C +P D C GS CLC+ GY
Sbjct: 373 IDRVGSFSCLCPPG--RTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGY---- 426
Query: 183 DGANC-RDVDEC---ERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC-VDINECHEE 341
G C +D+DEC ++ C+ C NT GS+ C C GY G C D NEC +
Sbjct: 427 SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY--TGSRCEADHNECLSQ 484
Query: 342 GVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRC--QAPCRNYAGGYR 512
C C++LL +F C+CP G EG C V+ +ECA + C A C + G++
Sbjct: 485 -PCHPGSTCLDLLATFHCLCPPG----LEGQLCEVETNECA-SAPCLNHADCHDLLNGFQ 538
Query: 513 CDCPVG 530
C C G
Sbjct: 539 CICLPG 544
Score = 83.4 bits (197), Expect = 5e-16
Identities = 57/179 (31%), Positives = 76/179 (42%), Gaps = 8/179 (4%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQL--CH-NTDGSYDCLCRTGYELDEDGAN 194
SF C C PG+ + D C P C + CH G C C G+ G
Sbjct: 102 SFLCTCLPGFTGERCQAQLEDPCP--PSFCSKRGRCHIQASGRPQCSCMPGWT----GEQ 155
Query: 195 CRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEE-GVCPSPGRC 368
C+ D C + +C T +C C G+E G AC D+NEC ++ G CP C
Sbjct: 156 CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFE--GHACERDVNECFQDPGPCPKGTSC 213
Query: 369 VNLLGSFRCVCP---RGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTV 536
N LGSF+C+CP G R + C R C+ G CQ + + C CP G +
Sbjct: 214 HNTLGSFQCLCPVGQEGPRCELRAGPCPPRG-CSNGGTCQLMPEKDSTFHLCLCPPGFI 271
Score = 82.2 bits (194), Expect = 1e-15
Identities = 61/182 (33%), Positives = 79/182 (43%), Gaps = 9/182 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N+ GSF CVC G+ D+C C + GS+ CLC G G
Sbjct: 336 NSAGSFHCVCVSGWGGTSCE-ENLDDCIAATCAPGSTCIDRVGSFSCLCPPG----RTGL 390
Query: 192 NCRDVDEC-ERDTHTCQQICSNT-EGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSP- 359
C D C + H Q +N GS C C+ GY G C D++EC PSP
Sbjct: 391 LCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS--GPTCHQDLDECLMAQQGPSPC 448
Query: 360 ---GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDEC-AQTGRCQAPCRNYAGGYRCDCP 524
G C+N GSF C+CP GY G+RC D +EC +Q + C + + C CP
Sbjct: 449 EHGGSCLNTPGSFNCLCPPGY----TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCP 504
Query: 525 VG 530
G
Sbjct: 505 PG 506
Score = 81.4 bits (192), Expect = 2e-15
Identities = 56/178 (31%), Positives = 79/178 (44%), Gaps = 4/178 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+NT GSF C+C PGY R +EC +P C + ++ CLC G E G
Sbjct: 455 LNTPGSFNCLCPPGY-TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLE----G 509
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
C + +EC C + ++C C G+ G C DI+EC C + G
Sbjct: 510 QLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFS--GTRCEEDIDEC-RSSPCANGG 566
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARC-VDRDEC-AQTGRCQAPCRNYAGGYRCDCPVG 530
+C + G+F C C G+ EG RC + DEC + A C + G + C CP G
Sbjct: 567 QCQDQPGAFHCKCLPGF----EGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSG 620
Score = 78.2 bits (184), Expect = 2e-14
Identities = 52/179 (29%), Positives = 80/179 (44%), Gaps = 4/179 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ + +F C+C PG V +ECA P CH+ + C+C G+ G
Sbjct: 493 LDLLATFHCLCPPGLEGQLCEVE-TNECASAPCLNHADCHDLLNGFQCICLPGFS----G 547
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
C D+DEC C + G++ C C G+E G C +++EC + CP
Sbjct: 548 TRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE--GPRCQTEVDECLSDP-CPVGA 604
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP--CRNYAGGYRCDCPVGT 533
C++L G+F C+CP G+ G C + CA CQ C++ C CP G+
Sbjct: 605 SCLDLPGAFFCLCPSGF----TGQLC-EVPLCA-PNLCQPKQICKDQKDKANCLCPDGS 657
Score = 70.9 bits (166), Expect = 3e-12
Identities = 60/191 (31%), Positives = 84/191 (43%), Gaps = 18/191 (9%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCD----------QLCHNTDGSYD-CLC 158
NT+GSF+C+C G G R C +R PC QL D ++ CLC
Sbjct: 215 NTLGSFQCLCPVGQE----GPR----CELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLC 266
Query: 159 RTGYELDEDGANCR-DVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACVDINE 329
G+ G +C + D C +H CQ C + +Y C C + + D D++E
Sbjct: 267 PPGFI----GPDCEVNPDNCV--SHQCQNGGTCQDGLDTYTCLCPETWTG-WDCSEDVDE 319
Query: 330 CHEEGV--CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DEC-AQTGRCQAPCRNY 497
C +G C + G C N GSF CVC G+ G C + D+C A T + C +
Sbjct: 320 CEAQGPPHCRNGGTCQNSAGSFHCVCVSGW----GGTSCEENLDDCIAATCAPGSTCIDR 375
Query: 498 AGGYRCDCPVG 530
G + C CP G
Sbjct: 376 VGSFSCLCPPG 386
Score = 70.1 bits (164), Expect = 5e-12
Identities = 53/187 (28%), Positives = 80/187 (42%), Gaps = 13/187 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
VN G+F C+C G++ + R CA P C ++ CLC TGY G
Sbjct: 785 VNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGY----TG 840
Query: 189 ANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHE----EGV- 347
+C+ +D C + C T S+ C C G+ G C + ++ C + +G+
Sbjct: 841 GSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGW--TGPLCNLPLSSCQKAALSQGID 898
Query: 348 ----CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ--APCRNYAGGY 509
C + G CV+ S+ C CP G+ +G+ C D ++ CQ A C GY
Sbjct: 899 VSSLCHNGGLCVDSGPSYFCHCPPGF----QGSLCQDHVNPCESRPCQNGATCMAQPSGY 954
Query: 510 RCDCPVG 530
C C G
Sbjct: 955 LCQCAPG 961
Score = 68.1 bits (159), Expect = 2e-11
Identities = 50/171 (29%), Positives = 69/171 (40%), Gaps = 5/171 (2%)
Frame = +3
Query: 33 CVCGPGYR-PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-RDV 206
CVC G+ P G C P C+ Y+C C TGY G C ++
Sbjct: 679 CVCDVGWTGPECEAELGG--CISAPCAHGGTCYPQPSGYNCTCPTGYT----GPTCSEEM 732
Query: 207 DECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGS 386
C C+ + G Y C+C + G C + C + G CVN G+
Sbjct: 733 TACHSGPCLNGGSCNPSPGGYYCTCPPSHT--GPQCQTSTDYCVSAPCFNGGTCVNRPGT 790
Query: 387 FRCVCPRGYRLDAEGARCVD--RDECAQTG-RCQAPCRNYAGGYRCDCPVG 530
F C+C G+ +G RC R CA + R +A C++ G RC CP G
Sbjct: 791 FSCLCAMGF----QGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTG 837
Score = 67.7 bits (158), Expect = 3e-11
Identities = 52/183 (28%), Positives = 74/183 (40%), Gaps = 14/183 (7%)
Frame = +3
Query: 30 RCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DV 206
RC+C GY G D CA +P P + C T S+ CLC G+ G C +
Sbjct: 831 RCLCPTGYT-GGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWT----GPLCNLPL 885
Query: 207 DECERD--------THTCQQ--ICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGVCP 353
C++ + C +C ++ SY C C G++ G C D +N C E C
Sbjct: 886 SSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLCQDHVNPC-ESRPCQ 942
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ--APCRNYAGGYRCDCPV 527
+ C+ + C C GY +G C + Q+ C C GG+ C CP
Sbjct: 943 NGATCMAQPSGYLCQCAPGY----DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPP 998
Query: 528 GTV 536
G V
Sbjct: 999 GFV 1001
Score = 66.1 bits (154), Expect = 8e-11
Identities = 45/144 (31%), Positives = 66/144 (45%), Gaps = 7/144 (4%)
Frame = +3
Query: 120 LCHNTDGSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQ--ICSNTEGSYECSCEDG 290
LC ++ SY C C G++ G+ C+D V+ CE + CQ C Y C C G
Sbjct: 908 LCVDSGPSYFCHCPPGFQ----GSLCQDHVNPCE--SRPCQNGATCMAQPSGYLCQCAPG 961
Query: 291 YEKRGDACV-DINECHEEGVCPSPGRCVNLLGSFRCVCPRGY---RLDAEGARCVDRDEC 458
Y+ G C +++ C + C + G C G F C CP G+ R + + C+D+ C
Sbjct: 962 YD--GQNCSKELDACQSQP-CHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQ-PC 1017
Query: 459 AQTGRCQAPCRNYAGGYRCDCPVG 530
TG A C + A + C C G
Sbjct: 1018 HPTG--TAACHSLANAFYCQCLPG 1039
Score = 60.9 bits (141), Expect = 3e-09
Identities = 52/188 (27%), Positives = 74/188 (39%), Gaps = 20/188 (10%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGR-DECAVRP--PPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
G F C C PG+ G G DEC +P P CH+ ++ C C G+ G
Sbjct: 990 GGFHCACPPGF--VGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT----GQ 1043
Query: 192 NCR-DVDECERDTHTCQQICSNTEGS---YECSCEDGYE-----KRGDACVDINECHEEG 344
C ++D C C T GS + C C G+E R +C + CH G
Sbjct: 1044 WCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSC-GFHHCHHGG 1102
Query: 345 VC---PSPG-----RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYA 500
+C P PG C++ G C+ P + + C+ C++T P
Sbjct: 1103 LCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGP----- 1157
Query: 501 GGYRCDCP 524
G+RC CP
Sbjct: 1158 -GFRCSCP 1164
>M17778-1|AAA36799.1| 640|Homo sapiens protein ( Human uromodulin
(Tamm-Horsfall glycoprotein) mRNA, complete cds. ).
Length = 640
Score = 90.6 bits (215), Expect = 3e-18
Identities = 44/101 (43%), Positives = 55/101 (54%), Gaps = 6/101 (5%)
Frame = +3
Query: 246 CSNTEGSYECSCEDGYEKRGDACVDINECHEEGV--CPSPGRCVNLLGSFRCVCPRGYRL 419
C+ E C+C++G+ G CVD++EC G C + CVN GSF CVCP G+RL
Sbjct: 41 CTEDEAVTTCTCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRL 100
Query: 420 DAEGARCVDRDECAQTG--RCQA--PCRNYAGGYRCDCPVG 530
+ G C D DECA+ G C A C N G Y C CP G
Sbjct: 101 -SPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAG 140
Score = 87.0 bits (206), Expect = 4e-17
Identities = 43/112 (38%), Positives = 57/112 (50%), Gaps = 6/112 (5%)
Frame = +3
Query: 123 CHNTDGSYDCLCRTGYELDEDGANCRDVDECE-RDTHTCQ--QICSNTEGSYECSCEDGY 293
C + C C+ G+ DG C D+DEC H C C NT GS+ C C +G+
Sbjct: 41 CTEDEAVTTCTCQEGFT--GDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGF 98
Query: 294 E-KRGDACVDINECHEEGV--CPSPGRCVNLLGSFRCVCPRGYRLDAEGARC 440
G C D++EC E G+ C + CVN++GS+ CVCP GYR D C
Sbjct: 99 RLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGDGWHCEC 150
Score = 64.5 bits (150), Expect = 2e-10
Identities = 56/168 (33%), Positives = 66/168 (39%), Gaps = 6/168 (3%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAV---RPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRD 203
C C G+ G DECA+ + C NT GS+ C+C G+ L G C D
Sbjct: 50 CTCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRL-SPGLGCTD 108
Query: 204 VDEC-ERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVN 374
VDEC E C + C N GSY C C GY G C EC SPG C
Sbjct: 109 VDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGDGWHC----EC-------SPGSCGP 157
Query: 375 LLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCD 518
L CV P G + C D + +T Y GY CD
Sbjct: 158 GLD---CV-PEG-----DALVCADPCQAHRTLDEYWRSTEYGEGYACD 196
Score = 48.0 bits (109), Expect = 2e-05
Identities = 32/68 (47%), Positives = 35/68 (51%), Gaps = 5/68 (7%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR-PAGRGVRGRDECAVRP--PPCDQL--CHNTDGSYDCLCRTGYE 173
VNT GSF CVC G+R G G DECA P C L C N GSY C+C GY
Sbjct: 84 VNTPGSFSCVCPEGFRLSPGLGCTDVDECA-EPGLSHCHALATCVNVVGSYLCVCPAGYR 142
Query: 174 LDEDGANC 197
DG +C
Sbjct: 143 --GDGWHC 148
Score = 46.4 bits (105), Expect = 7e-05
Identities = 30/83 (36%), Positives = 33/83 (39%), Gaps = 4/83 (4%)
Frame = +3
Query: 309 ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG--RCQA 482
A D +E C S C C C G+ D G CVD DECA G C A
Sbjct: 22 AATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGD--GLTCVDLDECAIPGAHNCSA 79
Query: 483 --PCRNYAGGYRCDCPVGTVRSP 545
C N G + C CP G SP
Sbjct: 80 NSSCVNTPGSFSCVCPEGFRLSP 102
>M15881-1|AAA36798.1| 640|Homo sapiens protein ( Human uromodulin
(Tamm-Horsfall glycoprotein) mRNA, complete cds. ).
Length = 640
Score = 90.6 bits (215), Expect = 3e-18
Identities = 44/101 (43%), Positives = 55/101 (54%), Gaps = 6/101 (5%)
Frame = +3
Query: 246 CSNTEGSYECSCEDGYEKRGDACVDINECHEEGV--CPSPGRCVNLLGSFRCVCPRGYRL 419
C+ E C+C++G+ G CVD++EC G C + CVN GSF CVCP G+RL
Sbjct: 41 CTEDEAVTTCTCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRL 100
Query: 420 DAEGARCVDRDECAQTG--RCQA--PCRNYAGGYRCDCPVG 530
+ G C D DECA+ G C A C N G Y C CP G
Sbjct: 101 -SPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAG 140
Score = 87.0 bits (206), Expect = 4e-17
Identities = 43/112 (38%), Positives = 57/112 (50%), Gaps = 6/112 (5%)
Frame = +3
Query: 123 CHNTDGSYDCLCRTGYELDEDGANCRDVDECE-RDTHTCQ--QICSNTEGSYECSCEDGY 293
C + C C+ G+ DG C D+DEC H C C NT GS+ C C +G+
Sbjct: 41 CTEDEAVTTCTCQEGFT--GDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGF 98
Query: 294 E-KRGDACVDINECHEEGV--CPSPGRCVNLLGSFRCVCPRGYRLDAEGARC 440
G C D++EC E G+ C + CVN++GS+ CVCP GYR D C
Sbjct: 99 RLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGDGWHCEC 150
Score = 64.5 bits (150), Expect = 2e-10
Identities = 56/168 (33%), Positives = 66/168 (39%), Gaps = 6/168 (3%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAV---RPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRD 203
C C G+ G DECA+ + C NT GS+ C+C G+ L G C D
Sbjct: 50 CTCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRL-SPGLGCTD 108
Query: 204 VDEC-ERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVN 374
VDEC E C + C N GSY C C GY G C EC SPG C
Sbjct: 109 VDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGDGWHC----EC-------SPGSCGP 157
Query: 375 LLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCD 518
L CV P G + C D + +T Y GY CD
Sbjct: 158 GLD---CV-PEG-----DALVCADPCQAHRTLDEYWRSTEYGEGYACD 196
Score = 48.0 bits (109), Expect = 2e-05
Identities = 32/68 (47%), Positives = 35/68 (51%), Gaps = 5/68 (7%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR-PAGRGVRGRDECAVRP--PPCDQL--CHNTDGSYDCLCRTGYE 173
VNT GSF CVC G+R G G DECA P C L C N GSY C+C GY
Sbjct: 84 VNTPGSFSCVCPEGFRLSPGLGCTDVDECA-EPGLSHCHALATCVNVVGSYLCVCPAGYR 142
Query: 174 LDEDGANC 197
DG +C
Sbjct: 143 --GDGWHC 148
Score = 46.4 bits (105), Expect = 7e-05
Identities = 30/83 (36%), Positives = 33/83 (39%), Gaps = 4/83 (4%)
Frame = +3
Query: 309 ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG--RCQA 482
A D +E C S C C C G+ D G CVD DECA G C A
Sbjct: 22 AATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGD--GLTCVDLDECAIPGAHNCSA 79
Query: 483 --PCRNYAGGYRCDCPVGTVRSP 545
C N G + C CP G SP
Sbjct: 80 NSSCVNTPGSFSCVCPEGFRLSP 102
>BC035975-1|AAH35975.1| 611|Homo sapiens UMOD protein protein.
Length = 611
Score = 90.6 bits (215), Expect = 3e-18
Identities = 44/101 (43%), Positives = 55/101 (54%), Gaps = 6/101 (5%)
Frame = +3
Query: 246 CSNTEGSYECSCEDGYEKRGDACVDINECHEEGV--CPSPGRCVNLLGSFRCVCPRGYRL 419
C+ E C+C++G+ G CVD++EC G C + CVN GSF CVCP G+RL
Sbjct: 41 CTEDEAVTTCTCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRL 100
Query: 420 DAEGARCVDRDECAQTG--RCQA--PCRNYAGGYRCDCPVG 530
+ G C D DECA+ G C A C N G Y C CP G
Sbjct: 101 -SPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAG 140
Score = 87.0 bits (206), Expect = 4e-17
Identities = 43/112 (38%), Positives = 57/112 (50%), Gaps = 6/112 (5%)
Frame = +3
Query: 123 CHNTDGSYDCLCRTGYELDEDGANCRDVDECE-RDTHTCQ--QICSNTEGSYECSCEDGY 293
C + C C+ G+ DG C D+DEC H C C NT GS+ C C +G+
Sbjct: 41 CTEDEAVTTCTCQEGFT--GDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGF 98
Query: 294 E-KRGDACVDINECHEEGV--CPSPGRCVNLLGSFRCVCPRGYRLDAEGARC 440
G C D++EC E G+ C + CVN++GS+ CVCP GYR D C
Sbjct: 99 RLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGDGWHCEC 150
Score = 64.5 bits (150), Expect = 2e-10
Identities = 56/168 (33%), Positives = 66/168 (39%), Gaps = 6/168 (3%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAV---RPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRD 203
C C G+ G DECA+ + C NT GS+ C+C G+ L G C D
Sbjct: 50 CTCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRL-SPGLGCTD 108
Query: 204 VDEC-ERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVN 374
VDEC E C + C N GSY C C GY G C EC SPG C
Sbjct: 109 VDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGDGWHC----EC-------SPGSCGP 157
Query: 375 LLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCD 518
L CV P G + C D + +T Y GY CD
Sbjct: 158 GLD---CV-PEG-----DALVCADPCQAHRTLDEYWRSTEYGEGYACD 196
Score = 48.0 bits (109), Expect = 2e-05
Identities = 32/68 (47%), Positives = 35/68 (51%), Gaps = 5/68 (7%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR-PAGRGVRGRDECAVRP--PPCDQL--CHNTDGSYDCLCRTGYE 173
VNT GSF CVC G+R G G DECA P C L C N GSY C+C GY
Sbjct: 84 VNTPGSFSCVCPEGFRLSPGLGCTDVDECA-EPGLSHCHALATCVNVVGSYLCVCPAGYR 142
Query: 174 LDEDGANC 197
DG +C
Sbjct: 143 --GDGWHC 148
Score = 46.4 bits (105), Expect = 7e-05
Identities = 30/83 (36%), Positives = 33/83 (39%), Gaps = 4/83 (4%)
Frame = +3
Query: 309 ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG--RCQA 482
A D +E C S C C C G+ D G CVD DECA G C A
Sbjct: 22 AATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGD--GLTCVDLDECAIPGAHNCSA 79
Query: 483 --PCRNYAGGYRCDCPVGTVRSP 545
C N G + C CP G SP
Sbjct: 80 NSSCVNTPGSFSCVCPEGFRLSP 102
>AY162970-1|AAO64446.1| 640|Homo sapiens uromodulin precursor
protein.
Length = 640
Score = 90.6 bits (215), Expect = 3e-18
Identities = 44/101 (43%), Positives = 55/101 (54%), Gaps = 6/101 (5%)
Frame = +3
Query: 246 CSNTEGSYECSCEDGYEKRGDACVDINECHEEGV--CPSPGRCVNLLGSFRCVCPRGYRL 419
C+ E C+C++G+ G CVD++EC G C + CVN GSF CVCP G+RL
Sbjct: 41 CTEDEAVTTCTCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRL 100
Query: 420 DAEGARCVDRDECAQTG--RCQA--PCRNYAGGYRCDCPVG 530
+ G C D DECA+ G C A C N G Y C CP G
Sbjct: 101 -SPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAG 140
Score = 87.0 bits (206), Expect = 4e-17
Identities = 43/112 (38%), Positives = 57/112 (50%), Gaps = 6/112 (5%)
Frame = +3
Query: 123 CHNTDGSYDCLCRTGYELDEDGANCRDVDECE-RDTHTCQ--QICSNTEGSYECSCEDGY 293
C + C C+ G+ DG C D+DEC H C C NT GS+ C C +G+
Sbjct: 41 CTEDEAVTTCTCQEGFT--GDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGF 98
Query: 294 E-KRGDACVDINECHEEGV--CPSPGRCVNLLGSFRCVCPRGYRLDAEGARC 440
G C D++EC E G+ C + CVN++GS+ CVCP GYR D C
Sbjct: 99 RLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGDGWHCEC 150
Score = 64.5 bits (150), Expect = 2e-10
Identities = 56/168 (33%), Positives = 66/168 (39%), Gaps = 6/168 (3%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAV---RPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRD 203
C C G+ G DECA+ + C NT GS+ C+C G+ L G C D
Sbjct: 50 CTCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRL-SPGLGCTD 108
Query: 204 VDEC-ERDTHTCQQI--CSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVN 374
VDEC E C + C N GSY C C GY G C EC SPG C
Sbjct: 109 VDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGDGWHC----EC-------SPGSCGP 157
Query: 375 LLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCD 518
L CV P G + C D + +T Y GY CD
Sbjct: 158 GLD---CV-PEG-----DALVCADPCQAHRTLDEYWRSTEYGEGYACD 196
Score = 48.0 bits (109), Expect = 2e-05
Identities = 32/68 (47%), Positives = 35/68 (51%), Gaps = 5/68 (7%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR-PAGRGVRGRDECAVRP--PPCDQL--CHNTDGSYDCLCRTGYE 173
VNT GSF CVC G+R G G DECA P C L C N GSY C+C GY
Sbjct: 84 VNTPGSFSCVCPEGFRLSPGLGCTDVDECA-EPGLSHCHALATCVNVVGSYLCVCPAGYR 142
Query: 174 LDEDGANC 197
DG +C
Sbjct: 143 --GDGWHC 148
Score = 46.4 bits (105), Expect = 7e-05
Identities = 30/83 (36%), Positives = 33/83 (39%), Gaps = 4/83 (4%)
Frame = +3
Query: 309 ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTG--RCQA 482
A D +E C S C C C G+ D G CVD DECA G C A
Sbjct: 22 AATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGD--GLTCVDLDECAIPGAHNCSA 79
Query: 483 --PCRNYAGGYRCDCPVGTVRSP 545
C N G + C CP G SP
Sbjct: 80 NSSCVNTPGSFSCVCPEGFRLSP 102
>AF111170-2|AAD15562.1| 1238|Homo sapiens Jagged2 protein.
Length = 1238
Score = 89.4 bits (212), Expect = 7e-18
Identities = 56/173 (32%), Positives = 82/173 (47%), Gaps = 5/173 (2%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-D 203
F C C G+ + DECA P C + ++C+C + GA C+ D
Sbjct: 369 FECHCPSGWSGPTCAL-DIDECASNPCAAGGTCVDQVDGFECICPEQWV----GATCQLD 423
Query: 204 VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNLL 380
+ECE C N G Y C C G+ +G C +++N+C G C G C +L+
Sbjct: 424 ANECEGKPCLNAFSCKNLIGGYYCDCIPGW--KGINCHINVNDCR--GQCQHGGTCKDLV 479
Query: 381 GSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQAP--CRNYAGGYRCDCPVG 530
++CVCPRG+ G C ++RDECA + C + C + A G+ C CP G
Sbjct: 480 NGYQCVCPRGF----GGRHCELERDECA-SSPCHSGGLCEDLADGFHCHCPQG 527
Score = 70.9 bits (166), Expect = 3e-12
Identities = 55/177 (31%), Positives = 75/177 (42%), Gaps = 5/177 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
V+ + F C+C P +EC +P C N G Y C C G++ G
Sbjct: 401 VDQVDGFECIC-PEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWK----G 455
Query: 189 ANCR-DVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSP 359
NC +V++C CQ C + Y+C C G+ R ++ +EC C S
Sbjct: 456 INCHINVNDCRGQ---CQHGGTCKDLVNGYQCVCPRGFGGR-HCELERDEC-ASSPCHSG 510
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTG-RCQAPCRNYAGGYRCDCP 524
G C +L F C CP+G+ G C VD D C + R A C N G Y C CP
Sbjct: 511 GLCEDLADGFHCHCPQGF----SGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACP 563
Score = 70.1 bits (164), Expect = 5e-12
Identities = 51/183 (27%), Positives = 81/183 (44%), Gaps = 7/183 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRD-ECAVRPPPCDQLCHNTDGSYDCLCRTGYELD 179
R + + F C C G++ G+ R+ +C C+++ ++ C C G++
Sbjct: 688 RCYDLVNDFYCACDDGWK--GKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWK-- 743
Query: 180 EDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVC 350
G+ C + C C + S+ C C DG+E G C + N+C+ C
Sbjct: 744 --GSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWE--GRTCTHNTNDCNPLP-C 798
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDC 521
+ G CV+ + FRC C G+ G C ++ DEC Q+ C A C + GYRC C
Sbjct: 799 YNGGICVDGVNWFRCECAPGFA----GPDCRINIDEC-QSSPCAYGATCVDEINGYRCSC 853
Query: 522 PVG 530
P G
Sbjct: 854 PPG 856
Score = 64.1 bits (149), Expect = 3e-10
Identities = 49/174 (28%), Positives = 77/174 (44%), Gaps = 4/174 (2%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 200
G+ R + G G AG G+ G V P + G++ C+C +G+ G C
Sbjct: 581 GACRVIDGCG-SDAGPGMPGTAASGVCGPH-GRCVSQPGGNFSCICDSGFT----GTYCH 634
Query: 201 D-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVN 374
+ +D+C C + ++ C C G+E G+ C + N+C + C S GRC +
Sbjct: 635 ENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWE--GELCDTNPNDCLPDP-CHSRGRCYD 691
Query: 375 LLGSFRCVCPRGYRLDAEGARCVDRD-EC-AQTGRCQAPCRNYAGGYRCDCPVG 530
L+ F C C G++ G C R+ +C A T C + +RC CP G
Sbjct: 692 LVNDFYCACDDGWK----GKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPG 741
Score = 61.3 bits (142), Expect = 2e-09
Identities = 52/169 (30%), Positives = 66/169 (39%), Gaps = 9/169 (5%)
Frame = +3
Query: 45 PGYRPAGRGVRGR--DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-RDVDEC 215
PG G +GR DEC P C + C C T + G C +D++ C
Sbjct: 259 PGECRCSYGWQGRFCDECVPYPGCVHGSCVEP---WQCNCETNW----GGLLCDKDLNYC 311
Query: 216 ERDTHTCQQ--ICSNTE-GSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGS 386
H C C N E Y C+C DGY R C C + G C +
Sbjct: 312 GSH-HPCTNGGTCINAEPDQYRCTCPDGYSGRN--CEKAEHACTSNPCANGGSCHEVPSG 368
Query: 387 FRCVCPRGYRLDAEGARC-VDRDECAQTGRCQA--PCRNYAGGYRCDCP 524
F C CP G+ G C +D DECA + C A C + G+ C CP
Sbjct: 369 FECHCPSGW----SGPTCALDIDECA-SNPCAAGGTCVDQVDGFECICP 412
Score = 56.8 bits (131), Expect = 5e-08
Identities = 38/156 (24%), Positives = 66/156 (42%), Gaps = 4/156 (2%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 200
G+F C+C G+ D+C +P C + ++ C C +G+E + N
Sbjct: 618 GNFSCICDSGFTGTYCH-ENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPN 676
Query: 201 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLL 380
D C D + C + + C+C+DG+ +G C + C + G C +
Sbjct: 677 D---CLPDPCHSRGRCYDLVNDFYCACDDGW--KGKTCHSREFQCDAYTCSNGGTCYDSG 731
Query: 381 GSFRCVCPRGYR----LDAEGARCVDRDECAQTGRC 476
+FRC CP G++ A+ + C+ + C G C
Sbjct: 732 DTFRCACPPGWKGSTCAVAKNSSCLP-NPCVNGGTC 766
Score = 51.6 bits (118), Expect = 2e-06
Identities = 47/177 (26%), Positives = 70/177 (39%), Gaps = 27/177 (15%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGY-----ELDED 185
F C C G+ V D P PC C+N +G Y C C + + +
Sbjct: 520 FHCHCPQGFSGPLCEV---DVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPRE 576
Query: 186 ---GANCRDVDECERDTH------TCQQIC-------SNTEGSYECSCEDGYEKRGDACV 317
G CR +D C D +C S G++ C C+ G+ G C
Sbjct: 577 PCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFT--GTYCH 634
Query: 318 D-INECHEEGVCPSPGRCVNLLGSFRCVCPRGYR---LDAEGARCVDRDECAQTGRC 476
+ I++C + C + G C++ + +FRC CP G+ D C+ D C GRC
Sbjct: 635 ENIDDCLGQP-CRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLP-DPCHSRGRC 689
Score = 50.4 bits (115), Expect = 4e-06
Identities = 27/92 (29%), Positives = 38/92 (41%), Gaps = 4/92 (4%)
Frame = +3
Query: 267 YECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNLL-GSFRCVCPRGYRLDAEGARC 440
++C+CE + G C D+N C C + G C+N +RC CP GY G C
Sbjct: 291 WQCNCETNWG--GLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGY----SGRNC 344
Query: 441 VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
+ + C C G+ C CP G
Sbjct: 345 EKAEHACTSNPCANGGSCHEVPSGFECHCPSG 376
>BC151219-1|AAI51220.1| 581|Homo sapiens matrilin 4 protein.
Length = 581
Score = 88.6 bits (210), Expect = 1e-17
Identities = 42/124 (33%), Positives = 62/124 (50%), Gaps = 5/124 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEG 263
D CA C+ C N+ GSY C C+ G+ L +D +CR +D C H+CQ C +T G
Sbjct: 217 DLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPG 276
Query: 264 SYECSCEDGYEKRGDACVDINECHEEGVCPSPG-----RCVNLLGSFRCVCPRGYRLDAE 428
C C +G++ + D C +C +CV+ S+RC+CP G +L A+
Sbjct: 277 GPRCHCREGHDLQPDG----RSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQAD 332
Query: 429 GARC 440
G C
Sbjct: 333 GKSC 336
Score = 72.1 bits (169), Expect = 1e-12
Identities = 47/149 (31%), Positives = 66/149 (44%), Gaps = 3/149 (2%)
Frame = +3
Query: 93 AVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYE 272
A+ PP D+ + S+D + G + C +D C TH C+ C N+ GSY
Sbjct: 183 AMASPPLDEHVFLVE-SFDLIQEFGLQFQS--RLCA-IDLCAEGTHGCEHHCVNSPGSYF 238
Query: 273 CSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
C C+ G+ + D +C I+ C G CV+ G RC C G+ L +G C
Sbjct: 239 CHCQVGFVLQQDQRSCRAIDYC-SFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQV 297
Query: 447 RDECAQTGR-CQAPCRNYAGGYRCDCPVG 530
RD C C+ C + YRC CP G
Sbjct: 298 RDLCNGVDHGCEFQCVSEGLSYRCLCPEG 326
Score = 69.3 bits (162), Expect = 8e-12
Identities = 37/112 (33%), Positives = 52/112 (46%), Gaps = 2/112 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN+ GS+ C C G+ + R R D C+ C C +T G C CR G++L
Sbjct: 231 VNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQP 290
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHE 338
DG +C+ D C H C+ C + SY C C +G + + D N C E
Sbjct: 291 DGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADG-KSCNRCRE 341
Score = 44.8 bits (101), Expect = 2e-04
Identities = 31/97 (31%), Positives = 41/97 (42%), Gaps = 1/97 (1%)
Frame = +3
Query: 264 SYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCV 443
S++ E G + + C I+ C EG CVN GS+ C C G+ L + C
Sbjct: 198 SFDLIQEFGLQFQSRLCA-IDLC-AEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCR 255
Query: 444 DRDECAQTGR-CQAPCRNYAGGYRCDCPVGTVRSPSG 551
D C+ CQ C + GG RC C G P G
Sbjct: 256 AIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDG 292
>BC131763-1|AAI31764.1| 581|Homo sapiens matrilin 4 protein.
Length = 581
Score = 88.6 bits (210), Expect = 1e-17
Identities = 42/124 (33%), Positives = 62/124 (50%), Gaps = 5/124 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEG 263
D CA C+ C N+ GSY C C+ G+ L +D +CR +D C H+CQ C +T G
Sbjct: 217 DLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPG 276
Query: 264 SYECSCEDGYEKRGDACVDINECHEEGVCPSPG-----RCVNLLGSFRCVCPRGYRLDAE 428
C C +G++ + D C +C +CV+ S+RC+CP G +L A+
Sbjct: 277 GPRCHCREGHDLQPDG----RSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQAD 332
Query: 429 GARC 440
G C
Sbjct: 333 GKSC 336
Score = 72.1 bits (169), Expect = 1e-12
Identities = 47/149 (31%), Positives = 66/149 (44%), Gaps = 3/149 (2%)
Frame = +3
Query: 93 AVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYE 272
A+ PP D+ + S+D + G + C +D C TH C+ C N+ GSY
Sbjct: 183 AMASPPLDEHVFLVE-SFDLIQEFGLQFQS--RLCA-IDLCAEGTHGCEHHCVNSPGSYF 238
Query: 273 CSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
C C+ G+ + D +C I+ C G CV+ G RC C G+ L +G C
Sbjct: 239 CHCQVGFVLQQDQRSCRAIDYC-SFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQV 297
Query: 447 RDECAQTGR-CQAPCRNYAGGYRCDCPVG 530
RD C C+ C + YRC CP G
Sbjct: 298 RDLCNGVDHGCEFQCVSEGLSYRCLCPEG 326
Score = 69.3 bits (162), Expect = 8e-12
Identities = 37/112 (33%), Positives = 52/112 (46%), Gaps = 2/112 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN+ GS+ C C G+ + R R D C+ C C +T G C CR G++L
Sbjct: 231 VNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQP 290
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHE 338
DG +C+ D C H C+ C + SY C C +G + + D N C E
Sbjct: 291 DGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADG-KSCNRCRE 341
Score = 44.8 bits (101), Expect = 2e-04
Identities = 31/97 (31%), Positives = 41/97 (42%), Gaps = 1/97 (1%)
Frame = +3
Query: 264 SYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCV 443
S++ E G + + C I+ C EG CVN GS+ C C G+ L + C
Sbjct: 198 SFDLIQEFGLQFQSRLCA-IDLC-AEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCR 255
Query: 444 DRDECAQTGR-CQAPCRNYAGGYRCDCPVGTVRSPSG 551
D C+ CQ C + GG RC C G P G
Sbjct: 256 AIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDG 292
>AL021578-2|CAB39280.1| 581|Homo sapiens matrilin 4 protein.
Length = 581
Score = 88.6 bits (210), Expect = 1e-17
Identities = 42/124 (33%), Positives = 62/124 (50%), Gaps = 5/124 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEG 263
D CA C+ C N+ GSY C C+ G+ L +D +CR +D C H+CQ C +T G
Sbjct: 217 DLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPG 276
Query: 264 SYECSCEDGYEKRGDACVDINECHEEGVCPSPG-----RCVNLLGSFRCVCPRGYRLDAE 428
C C +G++ + D C +C +CV+ S+RC+CP G +L A+
Sbjct: 277 GPRCHCREGHDLQPDG----RSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQAD 332
Query: 429 GARC 440
G C
Sbjct: 333 GKSC 336
Score = 72.1 bits (169), Expect = 1e-12
Identities = 47/149 (31%), Positives = 66/149 (44%), Gaps = 3/149 (2%)
Frame = +3
Query: 93 AVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYE 272
A+ PP D+ + S+D + G + C +D C TH C+ C N+ GSY
Sbjct: 183 AMASPPLDEHVFLVE-SFDLIQEFGLQFQS--RLCA-IDLCAEGTHGCEHHCVNSPGSYF 238
Query: 273 CSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
C C+ G+ + D +C I+ C G CV+ G RC C G+ L +G C
Sbjct: 239 CHCQVGFVLQQDQRSCRAIDYC-SFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQV 297
Query: 447 RDECAQTGR-CQAPCRNYAGGYRCDCPVG 530
RD C C+ C + YRC CP G
Sbjct: 298 RDLCNGVDHGCEFQCVSEGLSYRCLCPEG 326
Score = 69.3 bits (162), Expect = 8e-12
Identities = 37/112 (33%), Positives = 52/112 (46%), Gaps = 2/112 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN+ GS+ C C G+ + R R D C+ C C +T G C CR G++L
Sbjct: 231 VNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQP 290
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHE 338
DG +C+ D C H C+ C + SY C C +G + + D N C E
Sbjct: 291 DGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADG-KSCNRCRE 341
Score = 44.8 bits (101), Expect = 2e-04
Identities = 31/97 (31%), Positives = 41/97 (42%), Gaps = 1/97 (1%)
Frame = +3
Query: 264 SYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCV 443
S++ E G + + C I+ C EG CVN GS+ C C G+ L + C
Sbjct: 198 SFDLIQEFGLQFQSRLCA-IDLC-AEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCR 255
Query: 444 DRDECAQTGR-CQAPCRNYAGGYRCDCPVGTVRSPSG 551
D C+ CQ C + GG RC C G P G
Sbjct: 256 AIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDG 292
>AJ007581-1|CAA07569.1| 581|Homo sapiens matrilin-4 protein.
Length = 581
Score = 88.6 bits (210), Expect = 1e-17
Identities = 42/124 (33%), Positives = 62/124 (50%), Gaps = 5/124 (4%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEG 263
D CA C+ C N+ GSY C C+ G+ L +D +CR +D C H+CQ C +T G
Sbjct: 217 DLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPG 276
Query: 264 SYECSCEDGYEKRGDACVDINECHEEGVCPSPG-----RCVNLLGSFRCVCPRGYRLDAE 428
C C +G++ + D C +C +CV+ S+RC+CP G +L A+
Sbjct: 277 GPRCHCREGHDLQPDG----RSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQAD 332
Query: 429 GARC 440
G C
Sbjct: 333 GKSC 336
Score = 72.1 bits (169), Expect = 1e-12
Identities = 47/149 (31%), Positives = 66/149 (44%), Gaps = 3/149 (2%)
Frame = +3
Query: 93 AVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYE 272
A+ PP D+ + S+D + G + C +D C TH C+ C N+ GSY
Sbjct: 183 AMASPPLDEHVFLVE-SFDLIQEFGLQFQS--RLCA-IDLCAEGTHGCEHHCVNSPGSYF 238
Query: 273 CSCEDGYEKRGD--ACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
C C+ G+ + D +C I+ C G CV+ G RC C G+ L +G C
Sbjct: 239 CHCQVGFVLQQDQRSCRAIDYC-SFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQV 297
Query: 447 RDECAQTGR-CQAPCRNYAGGYRCDCPVG 530
RD C C+ C + YRC CP G
Sbjct: 298 RDLCNGVDHGCEFQCVSEGLSYRCLCPEG 326
Score = 69.3 bits (162), Expect = 8e-12
Identities = 37/112 (33%), Positives = 52/112 (46%), Gaps = 2/112 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGY--RPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN+ GS+ C C G+ + R R D C+ C C +T G C CR G++L
Sbjct: 231 VNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQP 290
Query: 183 DGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHE 338
DG +C+ D C H C+ C + SY C C +G + + D N C E
Sbjct: 291 DGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADG-KSCNRCRE 341
Score = 44.8 bits (101), Expect = 2e-04
Identities = 31/97 (31%), Positives = 41/97 (42%), Gaps = 1/97 (1%)
Frame = +3
Query: 264 SYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCV 443
S++ E G + + C I+ C EG CVN GS+ C C G+ L + C
Sbjct: 198 SFDLIQEFGLQFQSRLCA-IDLC-AEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCR 255
Query: 444 DRDECAQTGR-CQAPCRNYAGGYRCDCPVGTVRSPSG 551
D C+ CQ C + GG RC C G P G
Sbjct: 256 AIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDG 292
>AC013451-1|AAF87081.1| 969|Homo sapiens LTBP-2 protein.
Length = 969
Score = 88.6 bits (210), Expect = 1e-17
Identities = 44/107 (41%), Positives = 54/107 (50%), Gaps = 4/107 (3%)
Frame = +3
Query: 123 CHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGY--- 293
C N Y C+C GY+L A C D +EC RD + C N GSY C C GY
Sbjct: 861 CVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCINRVGSYSCFCYPGYTLA 920
Query: 294 -EKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEG 431
C DINEC + GVC S G+C N GS+ C C +GY + +G
Sbjct: 921 TSGATQECQDINECEQPGVC-SGGQCTNTEGSYHCECDQGYIMVRKG 966
Score = 83.8 bits (198), Expect = 4e-16
Identities = 45/123 (36%), Positives = 55/123 (44%), Gaps = 7/123 (5%)
Frame = +3
Query: 204 VDECERD-THTCQQ-ICSNTEGSYECSCEDGYEKRGDA--CVDINECHEEGVCPSPGRCV 371
+D C T+ C C N Y C C GY+ C D NEC + C GRC+
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDP-CKGKGRCI 903
Query: 372 NLLGSFRCVCPRGYRLDAEGA--RCVDRDECAQTGRCQ-APCRNYAGGYRCDCPVGTVRS 542
N +GS+ C C GY L GA C D +EC Q G C C N G Y C+C G +
Sbjct: 904 NRVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGYIMV 963
Query: 543 PSG 551
G
Sbjct: 964 RKG 966
Score = 82.6 bits (195), Expect = 8e-16
Identities = 41/99 (41%), Positives = 51/99 (51%), Gaps = 4/99 (4%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
VN +RCVC PGY+ P+ +EC P C N GSY C C GY L
Sbjct: 862 VNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCINRVGSYSCFCYPGYTLAT 921
Query: 183 DGA--NCRDVDECERDTHTCQQICSNTEGSYECSCEDGY 293
GA C+D++ECE+ C+NTEGSY C C+ GY
Sbjct: 922 SGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGY 960
Score = 50.4 bits (115), Expect = 4e-06
Identities = 30/87 (34%), Positives = 38/87 (43%), Gaps = 1/87 (1%)
Frame = +3
Query: 270 ECSCEDGYEKRG-DACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVD 446
+ C GY++ C DINEC G+C CVN GS+ C C G LD +RCV
Sbjct: 605 QLECPQGYKRLNLTHCQDINECLTLGLCKD-AECVNTRGSYLCTCRPGLMLDPSRSRCVS 663
Query: 447 RDECAQTGRCQAPCRNYAGGYRCDCPV 527
D+ Q C G C P+
Sbjct: 664 -DKA--ISMLQGLCYRSLGPGTCTLPL 687
Score = 46.4 bits (105), Expect = 7e-05
Identities = 26/67 (38%), Positives = 34/67 (50%), Gaps = 5/67 (7%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGV----RGRDECAVRPPPCD-QLCHNTDGSYDCLCRTG 167
R +N +GS+ C C PGY A G + +EC +P C C NT+GSY C C G
Sbjct: 901 RCINRVGSYSCFCYPGYTLATSGATQECQDINECE-QPGVCSGGQCTNTEGSYHCECDQG 959
Query: 168 YELDEDG 188
Y + G
Sbjct: 960 YIMVRKG 966
Score = 41.9 bits (94), Expect = 0.001
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 4/85 (4%)
Frame = +3
Query: 306 DACVDINECHEEGVC-PSPGRCVN-LLGSFRCVCPRGY-RLDAEGARCVDRDECAQTGRC 476
D C + +C P P R + ++ + + CP+GY RL+ C D +EC G C
Sbjct: 575 DCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQGYKRLNL--THCQDINECLTLGLC 632
Query: 477 Q-APCRNYAGGYRCDCPVGTVRSPS 548
+ A C N G Y C C G + PS
Sbjct: 633 KDAECVNTRGSYLCTCRPGLMLDPS 657
Score = 37.1 bits (82), Expect = 0.041
Identities = 32/114 (28%), Positives = 45/114 (39%), Gaps = 4/114 (3%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEG 263
+EC D C NT GSY C CR G LD + C ++ Q +C + G
Sbjct: 624 NECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRC----VSDKAISMLQGLCYRSLG 679
Query: 264 SYECS--CEDGYEKRGDACVDINEC--HEEGVCPSPGRCVNLLGSFRCVCPRGY 413
C+ K+ C + + E CP PG +FR +CP G+
Sbjct: 680 PGTCTLPLAQRITKQICCCSRVGKAWGSECEKCPLPG-----TEAFREICPAGH 728
>AF020201-1|AAB71189.1| 1238|Homo sapiens Jagged 2 protein.
Length = 1238
Score = 88.2 bits (209), Expect = 2e-17
Identities = 55/173 (31%), Positives = 83/173 (47%), Gaps = 5/173 (2%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-D 203
F C C G+ + DECA P C + ++C+C + GA C+ D
Sbjct: 369 FECHCPSGWSGPTCAL-DIDECASNPCAAGGTCVDQVDGFECICPEQWV----GATCQLD 423
Query: 204 VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNLL 380
V++CE C N G Y C C G+ +G C +++N+C G C G C +L+
Sbjct: 424 VNDCEGKPCLNAFSCKNLIGGYYCDCIPGW--KGINCHINVNDCR--GQCQHGGTCKDLV 479
Query: 381 GSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQAP--CRNYAGGYRCDCPVG 530
++CVCPRG+ G C ++RD+CA + C + C + A G+ C CP G
Sbjct: 480 NGYQCVCPRGF----GGRHCELERDKCA-SSPCHSGGLCEDLADGFHCHCPQG 527
Score = 70.1 bits (164), Expect = 5e-12
Identities = 51/183 (27%), Positives = 81/183 (44%), Gaps = 7/183 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRD-ECAVRPPPCDQLCHNTDGSYDCLCRTGYELD 179
R + + F C C G++ G+ R+ +C C+++ ++ C C G++
Sbjct: 688 RCYDLVNDFYCACDDGWK--GKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWK-- 743
Query: 180 EDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVC 350
G+ C + C C + S+ C C DG+E G C + N+C+ C
Sbjct: 744 --GSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWE--GRTCTHNTNDCNPLP-C 798
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDC 521
+ G CV+ + FRC C G+ G C ++ DEC Q+ C A C + GYRC C
Sbjct: 799 YNGGICVDGVNWFRCECAPGFA----GPDCRINIDEC-QSSPCAYGATCVDEINGYRCSC 853
Query: 522 PVG 530
P G
Sbjct: 854 PPG 856
Score = 67.7 bits (158), Expect = 3e-11
Identities = 54/177 (30%), Positives = 76/177 (42%), Gaps = 5/177 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
V+ + F C+C + A + D C +P C N G Y C C G++ G
Sbjct: 401 VDQVDGFECICPEQWVGATCQLDVND-CEGKPCLNAFSCKNLIGGYYCDCIPGWK----G 455
Query: 189 ANCR-DVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSP 359
NC +V++C CQ C + Y+C C G+ R ++ ++C C S
Sbjct: 456 INCHINVNDCRGQ---CQHGGTCKDLVNGYQCVCPRGFGGR-HCELERDKC-ASSPCHSG 510
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTG-RCQAPCRNYAGGYRCDCP 524
G C +L F C CP+G+ G C VD D C + R A C N G Y C CP
Sbjct: 511 GLCEDLADGFHCHCPQGF----SGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACP 563
Score = 64.1 bits (149), Expect = 3e-10
Identities = 49/174 (28%), Positives = 77/174 (44%), Gaps = 4/174 (2%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 200
G+ R + G G AG G+ G V P + G++ C+C +G+ G C
Sbjct: 581 GACRVIDGCG-SDAGPGMPGTAASGVCGPH-GRCVSQPGGNFSCICDSGFT----GTYCH 634
Query: 201 D-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVN 374
+ +D+C C + ++ C C G+E G+ C + N+C + C S GRC +
Sbjct: 635 ENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWE--GELCDTNPNDCLPDP-CHSRGRCYD 691
Query: 375 LLGSFRCVCPRGYRLDAEGARCVDRD-EC-AQTGRCQAPCRNYAGGYRCDCPVG 530
L+ F C C G++ G C R+ +C A T C + +RC CP G
Sbjct: 692 LVNDFYCACDDGWK----GKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPG 741
Score = 61.3 bits (142), Expect = 2e-09
Identities = 52/169 (30%), Positives = 66/169 (39%), Gaps = 9/169 (5%)
Frame = +3
Query: 45 PGYRPAGRGVRGR--DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-RDVDEC 215
PG G +GR DEC P C + C C T + G C +D++ C
Sbjct: 259 PGECRCSYGWQGRFCDECVPYPGCVHGSCVEP---WQCNCETNW----GGLLCDKDLNYC 311
Query: 216 ERDTHTCQQ--ICSNTE-GSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGS 386
H C C N E Y C+C DGY R C C + G C +
Sbjct: 312 GSH-HPCTNGGTCINAEPDQYRCTCPDGYSGRN--CEKAEHACTSNPCANGGSCHEVPSG 368
Query: 387 FRCVCPRGYRLDAEGARC-VDRDECAQTGRCQA--PCRNYAGGYRCDCP 524
F C CP G+ G C +D DECA + C A C + G+ C CP
Sbjct: 369 FECHCPSGW----SGPTCALDIDECA-SNPCAAGGTCVDQVDGFECICP 412
Score = 56.8 bits (131), Expect = 5e-08
Identities = 38/156 (24%), Positives = 66/156 (42%), Gaps = 4/156 (2%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 200
G+F C+C G+ D+C +P C + ++ C C +G+E + N
Sbjct: 618 GNFSCICDSGFTGTYCH-ENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPN 676
Query: 201 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLL 380
D C D + C + + C+C+DG+ +G C + C + G C +
Sbjct: 677 D---CLPDPCHSRGRCYDLVNDFYCACDDGW--KGKTCHSREFQCDAYTCSNGGTCYDSG 731
Query: 381 GSFRCVCPRGYR----LDAEGARCVDRDECAQTGRC 476
+FRC CP G++ A+ + C+ + C G C
Sbjct: 732 DTFRCACPPGWKGSTCAVAKNSSCLP-NPCVNGGTC 766
Score = 51.6 bits (118), Expect = 2e-06
Identities = 47/177 (26%), Positives = 70/177 (39%), Gaps = 27/177 (15%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGY-----ELDED 185
F C C G+ V D P PC C+N +G Y C C + + +
Sbjct: 520 FHCHCPQGFSGPLCEV---DVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPRE 576
Query: 186 ---GANCRDVDECERDTH------TCQQIC-------SNTEGSYECSCEDGYEKRGDACV 317
G CR +D C D +C S G++ C C+ G+ G C
Sbjct: 577 PCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFT--GTYCH 634
Query: 318 D-INECHEEGVCPSPGRCVNLLGSFRCVCPRGYR---LDAEGARCVDRDECAQTGRC 476
+ I++C + C + G C++ + +FRC CP G+ D C+ D C GRC
Sbjct: 635 ENIDDCLGQP-CRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLP-DPCHSRGRC 689
Score = 50.4 bits (115), Expect = 4e-06
Identities = 27/92 (29%), Positives = 38/92 (41%), Gaps = 4/92 (4%)
Frame = +3
Query: 267 YECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNLL-GSFRCVCPRGYRLDAEGARC 440
++C+CE + G C D+N C C + G C+N +RC CP GY G C
Sbjct: 291 WQCNCETNWG--GLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGY----SGRNC 344
Query: 441 VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
+ + C C G+ C CP G
Sbjct: 345 EKAEHACTSNPCANGGSCHEVPSGFECHCPSG 376
>BC053933-1|AAH53933.1| 239|Homo sapiens EMR2 protein protein.
Length = 239
Score = 87.8 bits (208), Expect = 2e-17
Identities = 43/112 (38%), Positives = 62/112 (55%), Gaps = 14/112 (12%)
Frame = +3
Query: 123 CHNTDGSYDCLCRTGYE--------LDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYE 272
C NT+GSYDC+C GYE +E C+DVDEC+++ C+ C NT GSY
Sbjct: 85 CWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYT 144
Query: 273 CSCEDGYE---KRGDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYR 416
C C G++ + C D+NEC + C S C+N +GS++C C G++
Sbjct: 145 CQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ 196
Score = 81.0 bits (191), Expect = 3e-15
Identities = 54/164 (32%), Positives = 73/164 (44%), Gaps = 23/164 (14%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCRTGYE-----LDEDGANCRDVDECERDTH-TCQQI--CSNTEG 263
P D C N C C G+ + C D++EC + +C + C NTEG
Sbjct: 34 PQDSSCVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEG 90
Query: 264 SYECSCEDGYEKRGDA----------CVDINECHEEG-VCPSPGRCVNLLGSFRCVCPRG 410
SY+C C GYE A C D++EC + +C S G CVN LGS+ C C G
Sbjct: 91 SYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPG 150
Query: 411 YRLDAEGAR-CVDRDECAQ-TGRCQAP--CRNYAGGYRCDCPVG 530
++ E + C D +EC C + C N G Y+C C G
Sbjct: 151 FKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPG 194
Score = 73.3 bits (172), Expect = 5e-13
Identities = 41/110 (37%), Positives = 51/110 (46%), Gaps = 15/110 (13%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG----------RGVRGRDECAVRPPPCDQ--LCHNTDGSYDCL 155
NT GS+ CVC PGY P + DEC P C C NT GSY C
Sbjct: 87 NTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQ 146
Query: 156 CRTGYE-LDEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYE 296
C G++ + ED C DV+EC + C C N GSY+C C G++
Sbjct: 147 CLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ 196
Score = 44.8 bits (101), Expect = 2e-04
Identities = 27/75 (36%), Positives = 35/75 (46%), Gaps = 5/75 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGV-RGRDECAVRPPPCDQLCH--NTDGSYDCLCRTGYE 173
VNT+GS+ C C PG++ P V +EC PC H N GSY C CR G++
Sbjct: 137 VNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ 196
Query: 174 LDEDGANCRDVDECE 218
N + CE
Sbjct: 197 PIPGSPNGPNNTVCE 211
>BC034949-1|AAH34949.1| 239|Homo sapiens EMR2 protein protein.
Length = 239
Score = 87.8 bits (208), Expect = 2e-17
Identities = 43/112 (38%), Positives = 62/112 (55%), Gaps = 14/112 (12%)
Frame = +3
Query: 123 CHNTDGSYDCLCRTGYE--------LDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYE 272
C NT+GSYDC+C GYE +E C+DVDEC+++ C+ C NT GSY
Sbjct: 85 CWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYT 144
Query: 273 CSCEDGYE---KRGDACVDINECHE-EGVCPSPGRCVNLLGSFRCVCPRGYR 416
C C G++ + C D+NEC + C S C+N +GS++C C G++
Sbjct: 145 CQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ 196
Score = 81.0 bits (191), Expect = 3e-15
Identities = 54/164 (32%), Positives = 73/164 (44%), Gaps = 23/164 (14%)
Frame = +3
Query: 108 PCDQLCHNTDGSYDCLCRTGYE-----LDEDGANCRDVDECERDTH-TCQQI--CSNTEG 263
P D C N C C G+ + C D++EC + +C + C NTEG
Sbjct: 34 PQDSSCVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEG 90
Query: 264 SYECSCEDGYEKRGDA----------CVDINECHEEG-VCPSPGRCVNLLGSFRCVCPRG 410
SY+C C GYE A C D++EC + +C S G CVN LGS+ C C G
Sbjct: 91 SYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPG 150
Query: 411 YRLDAEGAR-CVDRDECAQ-TGRCQAP--CRNYAGGYRCDCPVG 530
++ E + C D +EC C + C N G Y+C C G
Sbjct: 151 FKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPG 194
Score = 73.3 bits (172), Expect = 5e-13
Identities = 41/110 (37%), Positives = 51/110 (46%), Gaps = 15/110 (13%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAG----------RGVRGRDECAVRPPPCDQ--LCHNTDGSYDCL 155
NT GS+ CVC PGY P + DEC P C C NT GSY C
Sbjct: 87 NTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQ 146
Query: 156 CRTGYE-LDEDGANCRDVDECERDTHTCQQI--CSNTEGSYECSCEDGYE 296
C G++ + ED C DV+EC + C C N GSY+C C G++
Sbjct: 147 CLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ 196
Score = 44.8 bits (101), Expect = 2e-04
Identities = 27/75 (36%), Positives = 35/75 (46%), Gaps = 5/75 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYR--PAGRGV-RGRDECAVRPPPCDQLCH--NTDGSYDCLCRTGYE 173
VNT+GS+ C C PG++ P V +EC PC H N GSY C CR G++
Sbjct: 137 VNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQ 196
Query: 174 LDEDGANCRDVDECE 218
N + CE
Sbjct: 197 PIPGSPNGPNNTVCE 211
>AF029778-1|AAB84215.1| 1238|Homo sapiens Jagged2 protein.
Length = 1238
Score = 87.8 bits (208), Expect = 2e-17
Identities = 55/173 (31%), Positives = 82/173 (47%), Gaps = 5/173 (2%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-D 203
F C C G+ + DECA P C + ++C+C + GA C+ D
Sbjct: 369 FECHCPSGWSGPTCAL-DIDECASNPCAAGGTCVDQVDGFECICPEQWV----GATCQLD 423
Query: 204 VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNLL 380
+ECE C N G Y C C G+ +G C +++N+C G C G C +L+
Sbjct: 424 ANECEGKPCLNAFSCKNLIGGYYCDCIPGW--KGINCHINVNDCR--GQCQHGGTCKDLV 479
Query: 381 GSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQAP--CRNYAGGYRCDCPVG 530
++CVCPRG+ G C ++RD+CA + C + C + A G+ C CP G
Sbjct: 480 NGYQCVCPRGF----GGRHCELERDKCA-SSPCHSGGLCEDLADGFHCHCPQG 527
Score = 70.1 bits (164), Expect = 5e-12
Identities = 51/183 (27%), Positives = 81/183 (44%), Gaps = 7/183 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRD-ECAVRPPPCDQLCHNTDGSYDCLCRTGYELD 179
R + + F C C G++ G+ R+ +C C+++ ++ C C G++
Sbjct: 688 RCYDLVNDFYCACDDGWK--GKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWK-- 743
Query: 180 EDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVC 350
G+ C + C C + S+ C C DG+E G C + N+C+ C
Sbjct: 744 --GSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWE--GRTCTHNTNDCNPLP-C 798
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDC 521
+ G CV+ + FRC C G+ G C ++ DEC Q+ C A C + GYRC C
Sbjct: 799 YNGGICVDGVNWFRCECAPGFA----GPDCRINIDEC-QSSPCAYGATCVDEINGYRCSC 853
Query: 522 PVG 530
P G
Sbjct: 854 PPG 856
Score = 69.3 bits (162), Expect = 8e-12
Identities = 54/177 (30%), Positives = 75/177 (42%), Gaps = 5/177 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
V+ + F C+C P +EC +P C N G Y C C G++ G
Sbjct: 401 VDQVDGFECIC-PEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWK----G 455
Query: 189 ANCR-DVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSP 359
NC +V++C CQ C + Y+C C G+ R ++ ++C C S
Sbjct: 456 INCHINVNDCRGQ---CQHGGTCKDLVNGYQCVCPRGFGGR-HCELERDKC-ASSPCHSG 510
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTG-RCQAPCRNYAGGYRCDCP 524
G C +L F C CP+G+ G C VD D C + R A C N G Y C CP
Sbjct: 511 GLCEDLADGFHCHCPQGF----SGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACP 563
Score = 64.1 bits (149), Expect = 3e-10
Identities = 49/174 (28%), Positives = 77/174 (44%), Gaps = 4/174 (2%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 200
G+ R + G G AG G+ G V P + G++ C+C +G+ G C
Sbjct: 581 GACRVIDGCG-SDAGPGMPGTAASGVCGPH-GRCVSQPGGNFSCICDSGFT----GTYCH 634
Query: 201 D-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVN 374
+ +D+C C + ++ C C G+E G+ C + N+C + C S GRC +
Sbjct: 635 ENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWE--GELCDTNPNDCLPDP-CHSRGRCYD 691
Query: 375 LLGSFRCVCPRGYRLDAEGARCVDRD-EC-AQTGRCQAPCRNYAGGYRCDCPVG 530
L+ F C C G++ G C R+ +C A T C + +RC CP G
Sbjct: 692 LVNDFYCACDDGWK----GKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPG 741
Score = 61.3 bits (142), Expect = 2e-09
Identities = 52/169 (30%), Positives = 66/169 (39%), Gaps = 9/169 (5%)
Frame = +3
Query: 45 PGYRPAGRGVRGR--DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-RDVDEC 215
PG G +GR DEC P C + C C T + G C +D++ C
Sbjct: 259 PGECRCSYGWQGRFCDECVPYPGCVHGSCVEP---WQCNCETNW----GGLLCDKDLNYC 311
Query: 216 ERDTHTCQQ--ICSNTE-GSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGS 386
H C C N E Y C+C DGY R C C + G C +
Sbjct: 312 GSH-HPCTNGGTCINAEPDQYRCTCPDGYSGRN--CEKAEHACTSNPCANGGSCHEVPSG 368
Query: 387 FRCVCPRGYRLDAEGARC-VDRDECAQTGRCQA--PCRNYAGGYRCDCP 524
F C CP G+ G C +D DECA + C A C + G+ C CP
Sbjct: 369 FECHCPSGW----SGPTCALDIDECA-SNPCAAGGTCVDQVDGFECICP 412
Score = 56.8 bits (131), Expect = 5e-08
Identities = 38/156 (24%), Positives = 66/156 (42%), Gaps = 4/156 (2%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 200
G+F C+C G+ D+C +P C + ++ C C +G+E + N
Sbjct: 618 GNFSCICDSGFTGTYCH-ENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPN 676
Query: 201 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLL 380
D C D + C + + C+C+DG+ +G C + C + G C +
Sbjct: 677 D---CLPDPCHSRGRCYDLVNDFYCACDDGW--KGKTCHSREFQCDAYTCSNGGTCYDSG 731
Query: 381 GSFRCVCPRGYR----LDAEGARCVDRDECAQTGRC 476
+FRC CP G++ A+ + C+ + C G C
Sbjct: 732 DTFRCACPPGWKGSTCAVAKNSSCLP-NPCVNGGTC 766
Score = 51.6 bits (118), Expect = 2e-06
Identities = 47/177 (26%), Positives = 70/177 (39%), Gaps = 27/177 (15%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGY-----ELDED 185
F C C G+ V D P PC C+N +G Y C C + + +
Sbjct: 520 FHCHCPQGFSGPLCEV---DVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPRE 576
Query: 186 ---GANCRDVDECERDTH------TCQQIC-------SNTEGSYECSCEDGYEKRGDACV 317
G CR +D C D +C S G++ C C+ G+ G C
Sbjct: 577 PCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFT--GTYCH 634
Query: 318 D-INECHEEGVCPSPGRCVNLLGSFRCVCPRGYR---LDAEGARCVDRDECAQTGRC 476
+ I++C + C + G C++ + +FRC CP G+ D C+ D C GRC
Sbjct: 635 ENIDDCLGQP-CRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLP-DPCHSRGRC 689
Score = 50.4 bits (115), Expect = 4e-06
Identities = 27/92 (29%), Positives = 38/92 (41%), Gaps = 4/92 (4%)
Frame = +3
Query: 267 YECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNLL-GSFRCVCPRGYRLDAEGARC 440
++C+CE + G C D+N C C + G C+N +RC CP GY G C
Sbjct: 291 WQCNCETNWG--GLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGY----SGRNC 344
Query: 441 VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
+ + C C G+ C CP G
Sbjct: 345 EKAEHACTSNPCANGGSCHEVPSGFECHCPSG 376
>AF003521-1|AAB61285.1| 1238|Homo sapiens Jagged 2 protein.
Length = 1238
Score = 87.8 bits (208), Expect = 2e-17
Identities = 55/173 (31%), Positives = 82/173 (47%), Gaps = 5/173 (2%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-D 203
F C C G+ + DECA P C + ++C+C + GA C+ D
Sbjct: 369 FECHCPSGWSGPTCAL-DIDECASNPCAAGGTCVDQVDGFECICPEQWV----GATCQLD 423
Query: 204 VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNLL 380
+ECE C N G Y C C G+ +G C +++N+C G C G C +L+
Sbjct: 424 ANECEGKPCLNAFSCKNLIGGYYCDCIPGW--KGINCHINVNDCR--GQCQHGGTCKDLV 479
Query: 381 GSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQAP--CRNYAGGYRCDCPVG 530
++CVCPRG+ G C ++RD+CA + C + C + A G+ C CP G
Sbjct: 480 NGYQCVCPRGF----GGRHCELERDKCA-SSPCHSGGLCEDLADGFHCHCPQG 527
Score = 70.1 bits (164), Expect = 5e-12
Identities = 51/183 (27%), Positives = 81/183 (44%), Gaps = 7/183 (3%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRD-ECAVRPPPCDQLCHNTDGSYDCLCRTGYELD 179
R + + F C C G++ G+ R+ +C C+++ ++ C C G++
Sbjct: 688 RCYDLVNDFYCACDDGWK--GKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWK-- 743
Query: 180 EDGANCRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVC 350
G+ C + C C + S+ C C DG+E G C + N+C+ C
Sbjct: 744 --GSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWE--GRTCTHNTNDCNPLP-C 798
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDC 521
+ G CV+ + FRC C G+ G C ++ DEC Q+ C A C + GYRC C
Sbjct: 799 YNGGICVDGVNWFRCECAPGFA----GPDCRINIDEC-QSSPCAYGATCVDEINGYRCSC 853
Query: 522 PVG 530
P G
Sbjct: 854 PPG 856
Score = 69.3 bits (162), Expect = 8e-12
Identities = 54/177 (30%), Positives = 75/177 (42%), Gaps = 5/177 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
V+ + F C+C P +EC +P C N G Y C C G++ G
Sbjct: 401 VDQVDGFECIC-PEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWK----G 455
Query: 189 ANCR-DVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSP 359
NC +V++C CQ C + Y+C C G+ R ++ ++C C S
Sbjct: 456 INCHINVNDCRGQ---CQHGGTCKDLVNGYQCVCPRGFGGR-HCELERDKC-ASSPCHSG 510
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTG-RCQAPCRNYAGGYRCDCP 524
G C +L F C CP+G+ G C VD D C + R A C N G Y C CP
Sbjct: 511 GLCEDLADGFHCHCPQGF----SGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACP 563
Score = 64.1 bits (149), Expect = 3e-10
Identities = 49/174 (28%), Positives = 77/174 (44%), Gaps = 4/174 (2%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 200
G+ R + G G AG G+ G V P + G++ C+C +G+ G C
Sbjct: 581 GACRVIDGCG-SDAGPGMPGTAASGVCGPH-GRCVSQPGGNFSCICDSGFT----GTYCH 634
Query: 201 D-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVN 374
+ +D+C C + ++ C C G+E G+ C + N+C + C S GRC +
Sbjct: 635 ENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWE--GELCDTNPNDCLPDP-CHSRGRCYD 691
Query: 375 LLGSFRCVCPRGYRLDAEGARCVDRD-EC-AQTGRCQAPCRNYAGGYRCDCPVG 530
L+ F C C G++ G C R+ +C A T C + +RC CP G
Sbjct: 692 LVNDFYCACDDGWK----GKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPG 741
Score = 61.3 bits (142), Expect = 2e-09
Identities = 52/169 (30%), Positives = 66/169 (39%), Gaps = 9/169 (5%)
Frame = +3
Query: 45 PGYRPAGRGVRGR--DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-RDVDEC 215
PG G +GR DEC P C + C C T + G C +D++ C
Sbjct: 259 PGECRCSYGWQGRFCDECVPYPGCVHGSCVEP---WQCNCETNW----GGLLCDKDLNYC 311
Query: 216 ERDTHTCQQ--ICSNTE-GSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGS 386
H C C N E Y C+C DGY R C C + G C +
Sbjct: 312 GSH-HPCTNGGTCINAEPDQYRCTCPDGYSGRN--CEKAEHACTSNPCANGGSCHEVPSG 368
Query: 387 FRCVCPRGYRLDAEGARC-VDRDECAQTGRCQA--PCRNYAGGYRCDCP 524
F C CP G+ G C +D DECA + C A C + G+ C CP
Sbjct: 369 FECHCPSGW----SGPTCALDIDECA-SNPCAAGGTCVDQVDGFECICP 412
Score = 56.8 bits (131), Expect = 5e-08
Identities = 38/156 (24%), Positives = 66/156 (42%), Gaps = 4/156 (2%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 200
G+F C+C G+ D+C +P C + ++ C C +G+E + N
Sbjct: 618 GNFSCICDSGFTGTYCH-ENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPN 676
Query: 201 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLL 380
D C D + C + + C+C+DG+ +G C + C + G C +
Sbjct: 677 D---CLPDPCHSRGRCYDLVNDFYCACDDGW--KGKTCHSREFQCDAYTCSNGGTCYDSG 731
Query: 381 GSFRCVCPRGYR----LDAEGARCVDRDECAQTGRC 476
+FRC CP G++ A+ + C+ + C G C
Sbjct: 732 DTFRCACPPGWKGSTCAVAKNSSCLP-NPCVNGGTC 766
Score = 51.6 bits (118), Expect = 2e-06
Identities = 47/177 (26%), Positives = 70/177 (39%), Gaps = 27/177 (15%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGY-----ELDED 185
F C C G+ V D P PC C+N +G Y C C + + +
Sbjct: 520 FHCHCPQGFSGPLCEV---DVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPRE 576
Query: 186 ---GANCRDVDECERDTH------TCQQIC-------SNTEGSYECSCEDGYEKRGDACV 317
G CR +D C D +C S G++ C C+ G+ G C
Sbjct: 577 PCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFT--GTYCH 634
Query: 318 D-INECHEEGVCPSPGRCVNLLGSFRCVCPRGYR---LDAEGARCVDRDECAQTGRC 476
+ I++C + C + G C++ + +FRC CP G+ D C+ D C GRC
Sbjct: 635 ENIDDCLGQP-CRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLP-DPCHSRGRC 689
Score = 50.4 bits (115), Expect = 4e-06
Identities = 27/92 (29%), Positives = 38/92 (41%), Gaps = 4/92 (4%)
Frame = +3
Query: 267 YECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNLL-GSFRCVCPRGYRLDAEGARC 440
++C+CE + G C D+N C C + G C+N +RC CP GY G C
Sbjct: 291 WQCNCETNWG--GLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGY----SGRNC 344
Query: 441 VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
+ + C C G+ C CP G
Sbjct: 345 EKAEHACTSNPCANGGSCHEVPSGFECHCPSG 376
>AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1,
translocation-associated (Drosophila) protein.
Length = 2555
Score = 87.4 bits (207), Expect = 3e-17
Identities = 54/175 (30%), Positives = 78/175 (44%), Gaps = 4/175 (2%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
+ +F C+C PGY +EC+ +P C + D +Y C C G G NC
Sbjct: 584 VATFTCLCRPGYT-GHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKG----TTGPNC 638
Query: 198 R-DVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRC 368
++D+C + C C + YEC+CE GY G C ++I+EC C + G C
Sbjct: 639 EINLDDCA--SSPCDSGTCLDKIDGYECACEPGYT--GSMCNINIDEC-AGNPCHNGGTC 693
Query: 369 VNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQAPCRNYAGGYRCDCPVG 530
+ + F C CP GY C+ +EC CR+ GY+CDC G
Sbjct: 694 EDGINGFTCRCPEGYH----DPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPG 744
Score = 83.8 bits (198), Expect = 4e-16
Identities = 61/180 (33%), Positives = 79/180 (43%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVR-GRDECAVRPPPCDQLCHNTDG--SYDCLCRTGYELDE 182
NT G +RC C GY +GR D+C RP PC TDG + C C G+
Sbjct: 886 NTHGGYRCHCQAGY--SGRNCETDIDDC--RPNPCHNGGSCTDGINTAFCDCLPGFR--- 938
Query: 183 DGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSP 359
G C D++EC D C++ SY C+C G+ G C + E C +
Sbjct: 939 -GTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFS--GIHCENNTPDCTESSCFNG 995
Query: 360 GRCVNLLGSFRCVCPRGYR---LDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
G CV+ + SF C+CP G+ + C D C G CQ C G YRC CP G
Sbjct: 996 GTCVDGINSFTCLCPPGFTGSYCQHDVNEC-DSQPCLHGGTCQDGC----GSYRCTCPQG 1050
Score = 83.4 bits (197), Expect = 5e-16
Identities = 53/177 (29%), Positives = 76/177 (42%), Gaps = 3/177 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+NT+GSF C C GY R +EC P D C + G + C+C GYE G
Sbjct: 430 INTLGSFECQCLQGYT-GPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYE----G 484
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
+C + DEC C + ++C C G+ G C D++EC C +
Sbjct: 485 VHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGF--TGHLCQYDVDEC-ASTPCKNGA 541
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
+C++ ++ CVC GY G C VD DEC C++ + C C G
Sbjct: 542 KCLDGPNTYTCVCTEGY----TGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPG 594
Score = 78.6 bits (185), Expect = 1e-14
Identities = 52/173 (30%), Positives = 73/173 (42%), Gaps = 4/173 (2%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 200
SF CVC G++ V +EC + P C NT G Y C C+ GY G NC
Sbjct: 852 SFSCVCPTGWQGQTCEV-DINECVLSPCRHGASCQNTHGGYRCHCQAGY----SGRNCET 906
Query: 201 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNL 377
D+D+C + C++ + C C G+ RG C DINEC + C + C +
Sbjct: 907 DIDDCRPNPCHNGGSCTDGINTAFCDCLPGF--RGTFCEEDINECASD-PCRNGANCTDC 963
Query: 378 LGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC--QAPCRNYAGGYRCDCPVG 530
+ S+ C CP G+ G C + C C + + C CP G
Sbjct: 964 VDSYTCTCPAGF----SGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPG 1012
Score = 77.0 bits (181), Expect = 4e-14
Identities = 58/180 (32%), Positives = 76/180 (42%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
NT G + CVC G+ D+CA CH+ S+ C C G G
Sbjct: 314 NTHGGYNCVCVNGWTGEDCS-ENIDDCASAACFHGATCHDRVASFYCECPHG----RTGL 368
Query: 192 NCRDVDECERDTHTCQQICSNT--EGSYECSCEDGYEKRGDACV-DINECH-EEGVCPSP 359
C D C + C G C+C GY G AC D++EC C
Sbjct: 369 LCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYT--GPACSQDVDECSLGANPCEHA 426
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
G+C+N LGSF C C +GY G RC +D +EC + CQ A C + G ++C C G
Sbjct: 427 GKCINTLGSFECQCLQGY----TGPRCEIDVNECV-SNPCQNDATCLDQIGEFQCICMPG 481
Score = 76.2 bits (179), Expect = 7e-14
Identities = 50/176 (28%), Positives = 80/176 (45%), Gaps = 5/176 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ I + C C PGY + + DECA P C + + C C GY D
Sbjct: 656 LDKIDGYECACEPGYTGSMCNI-NIDECAGNPCHNGGTCEDGINGFTCRCPEGY---HDP 711
Query: 189 ANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
+V+EC +++ C C ++ Y+C C+ G+ G C ++ NEC E C + G
Sbjct: 712 TCLSEVNEC--NSNPCVHGACRDSLNGYKCDCDPGWS--GTNCDINNNEC-ESNPCVNGG 766
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRC--QAPCRNYAGGYRCDC 521
C ++ + C C G+ G C + +ECA + C Q C + GY+C+C
Sbjct: 767 TCKDMTSGYVCTCREGF----SGPNCQTNINECA-SNPCLNQGTCIDDVAGYKCNC 817
Score = 75.8 bits (178), Expect = 1e-13
Identities = 48/151 (31%), Positives = 72/151 (47%), Gaps = 12/151 (7%)
Frame = +3
Query: 120 LCHNTDGSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYE 296
LC + ++ C C+ GY G+ C D VDEC C++ G Y C C GY
Sbjct: 1121 LCVDAGNTHHCRCQAGYT----GSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYH 1176
Query: 297 KRGDACVD-INECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDEC---- 458
G C + I+EC C + G C++L +++C CPRG +G C ++ D+C
Sbjct: 1177 --GVNCSEEIDECLSHP-CQNGGTCLDLPNTYKCSCPRG----TQGVHCEINVDDCNPPV 1229
Query: 459 ---AQTGRC--QAPCRNYAGGYRCDCPVGTV 536
+++ +C C + GGY C CP G V
Sbjct: 1230 DPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV 1260
Score = 74.5 bits (175), Expect = 2e-13
Identities = 53/181 (29%), Positives = 76/181 (41%), Gaps = 8/181 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNT-DGSYDCLCRTGYELDE 182
N +GS+RCVC + G R P PC C T D +++C C G+
Sbjct: 197 NEVGSYRCVCRATH--TGPNCE-RPYVPCSPSPCQNGGTCRPTGDVTHECACLPGF---- 249
Query: 183 DGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECH-EEGVCP 353
G NC + +D+C + C + +Y C C E G C D++EC C
Sbjct: 250 TGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPP--EWTGQYCTEDVDECQLMPNACQ 307
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ-APCRNYAGGYRCDCPV 527
+ G C N G + CVC G+ G C + D+CA A C + + C+CP
Sbjct: 308 NGGTCHNTHGGYNCVCVNGW----TGEDCSENIDDCASAACFHGATCHDRVASFYCECPH 363
Query: 528 G 530
G
Sbjct: 364 G 364
Score = 73.3 bits (172), Expect = 5e-13
Identities = 61/188 (32%), Positives = 78/188 (41%), Gaps = 14/188 (7%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
V+ I SF C+C PG+ +EC +P C + GSY C C GY G
Sbjct: 999 VDGINSFTCLCPPGFT-GSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYT----G 1053
Query: 189 ANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECH----EEGV- 347
NC++ V C+ C T Y C C G+ G C V C +GV
Sbjct: 1054 PNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWT--GLYCDVPSVSCEVAAQRQGVD 1111
Query: 348 ----CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ--APCRNYAGG 506
C G CV+ + C C GY G+ C D DEC+ + CQ A C +Y GG
Sbjct: 1112 VARLCQHGGLCVDAGNTHHCRCQAGY----TGSYCEDLVDECSPS-PCQNGATCTDYLGG 1166
Query: 507 YRCDCPVG 530
Y C C G
Sbjct: 1167 YSCKCVAG 1174
Score = 72.5 bits (170), Expect = 9e-13
Identities = 55/185 (29%), Positives = 76/185 (41%), Gaps = 11/185 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDE 182
V+ + ++ C C P + DEC + P C CHNT G Y+C+C G+
Sbjct: 273 VDGVNTYNCRCPPEWT-GQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGW---- 327
Query: 183 DGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYE----KRGDACVDINECHEEGV 347
G +C ++D+C C + S+ C C G DAC+ N C+E
Sbjct: 328 TGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACIS-NPCNEGSN 386
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECA-QTGRCQ--APCRNYAGGYRC 515
C + VN G C CP GY G C D DEC+ C+ C N G + C
Sbjct: 387 CDT--NPVN--GKAICTCPSGY----TGPACSQDVDECSLGANPCEHAGKCINTLGSFEC 438
Query: 516 DCPVG 530
C G
Sbjct: 439 QCLQG 443
Score = 71.7 bits (168), Expect = 2e-12
Identities = 54/179 (30%), Positives = 76/179 (42%), Gaps = 4/179 (2%)
Frame = +3
Query: 6 GVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
G+NT +F C C PG+R +ECA P C + SY C C G+
Sbjct: 925 GINT--AF-CDCLPGFRGTFCE-EDINECASDPCRNGANCTDCVDSYTCTCPAGFS---- 976
Query: 186 GANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSP 359
G +C + +C + C + S+ C C G+ G C D+NEC + C
Sbjct: 977 GIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFT--GSYCQHDVNECDSQP-CLHG 1033
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
G C + GS+RC CP+GY G C + + C+ C YRC+CP G
Sbjct: 1034 GTCQDGCGSYRCTCPQGY----TGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSG 1088
Score = 71.7 bits (168), Expect = 2e-12
Identities = 54/166 (32%), Positives = 76/166 (45%), Gaps = 17/166 (10%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTD--GSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQ--IC 248
DEC+ P PC TD G Y C C GY G NC ++DEC +H CQ C
Sbjct: 1147 DECS--PSPCQNGATCTDYLGGYSCKCVAGYH----GVNCSEEIDECL--SHPCQNGGTC 1198
Query: 249 SNTEGSYECSCEDGYEKRGDAC-VDINECHE--EGVCPSP-----GRCVNLLGSFRCVCP 404
+ +Y+CSC G +G C +++++C+ + V SP G CV+ +G + C CP
Sbjct: 1199 LDLPNTYKCSCPRG--TQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCP 1256
Query: 405 RGYRLDAEGARCV-DRDECAQT---GRCQAPCRNYAGGYRCDCPVG 530
G+ G RC D +EC R C + C+C G
Sbjct: 1257 PGF----VGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAG 1298
Score = 70.9 bits (166), Expect = 3e-12
Identities = 57/179 (31%), Positives = 78/179 (43%), Gaps = 10/179 (5%)
Frame = +3
Query: 24 SFRCVCGPGYR-PAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGAN 194
S+ C C P + P R + +EC +P C CHN GSY C+CR + G N
Sbjct: 161 SYICHCPPSFHGPTCR--QDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATH----TGPN 214
Query: 195 C-RDVDECERDTHTCQQICSNT-EGSYECSCEDGYEKRGDACVD-INECHEEGVCPSPGR 365
C R C C T + ++EC+C G+ G C + I++C C + G
Sbjct: 215 CERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGF--TGQNCEENIDDCPGNN-CKNGGA 271
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARCV-DRDEC-AQTGRCQ--APCRNYAGGYRCDCPVG 530
CV+ + ++ C CP + G C D DEC CQ C N GGY C C G
Sbjct: 272 CVDGVNTYNCRCPPEW----TGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNG 326
Score = 70.5 bits (165), Expect = 4e-12
Identities = 52/175 (29%), Positives = 78/175 (44%), Gaps = 6/175 (3%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCR 200
++ CVC GY V DEC P PC C + ++ CLCR GY G +C
Sbjct: 549 TYTCVCTEGYTGTHCEV-DIDECD--PDPCHYGSCKDGVATFTCLCRPGY----TGHHCE 601
Query: 201 -DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVN 374
+++EC C + + +Y C C G G C +++++C C S G C++
Sbjct: 602 TNINECSSQPCRHGGTCQDRDNAYLCFCLKG--TTGPNCEINLDDC-ASSPCDS-GTCLD 657
Query: 375 LLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
+ + C C GY G+ C ++ DECA C C + G+ C CP G
Sbjct: 658 KIDGYECACEPGY----TGSMCNINIDECA-GNPCHNGGTCEDGINGFTCRCPEG 707
Score = 64.9 bits (151), Expect = 2e-10
Identities = 52/186 (27%), Positives = 73/186 (39%), Gaps = 15/186 (8%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
+G + C C GY DEC P C + +Y C C G + G +C
Sbjct: 1164 LGGYSCKCVAGYHGVNCSEE-IDECLSHPCQNGGTCLDLPNTYKCSCPRGTQ----GVHC 1218
Query: 198 R-DVDECERDTHTCQQ--------ICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGV 347
+VD+C + C + G Y C+C G+ G+ C D+NEC
Sbjct: 1219 EINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV--GERCEGDVNECLSNP- 1275
Query: 348 CPSPG--RCVNLLGSFRCVCPRGY---RLDAEGARCVDRDECAQTGRCQAPCRNYAGGYR 512
C + G CV + F C C G+ R ++ C + C G C A N A G+
Sbjct: 1276 CDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKP-CKNGGTC-AVASNTARGFI 1333
Query: 513 CDCPVG 530
C CP G
Sbjct: 1334 CKCPAG 1339
Score = 60.1 bits (139), Expect = 5e-09
Identities = 41/140 (29%), Positives = 61/140 (43%), Gaps = 8/140 (5%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPC-DQLCHN----TDG--SYDCLCRTGYEL 176
+ S+ C C G+ G+ C P C + C N DG S+ CLC G+
Sbjct: 964 VDSYTCTCPAGFS----GIH----CENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFT- 1014
Query: 177 DEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCP 353
G+ C+ DV+EC+ C + GSY C+C GY G C ++ + C
Sbjct: 1015 ---GSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYT--GPNCQNLVHWCDSSPCK 1069
Query: 354 SPGRCVNLLGSFRCVCPRGY 413
+ G+C +RC CP G+
Sbjct: 1070 NGGKCWQTHTQYRCECPSGW 1089
Score = 59.7 bits (138), Expect = 7e-09
Identities = 49/178 (27%), Positives = 74/178 (41%), Gaps = 7/178 (3%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGAN 194
I F C C GY + +EC PC C ++ Y C C G+ G N
Sbjct: 697 INGFTCRCPEGYHDP-TCLSEVNEC--NSNPCVHGACRDSLNGYKCDCDPGWS----GTN 749
Query: 195 CRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGR 365
C D++ E +++ C C + Y C+C +G+ G C +INEC C + G
Sbjct: 750 C-DINNNECESNPCVNGGTCKDMTSGYVCTCREGFS--GPNCQTNINEC-ASNPCLNQGT 805
Query: 366 CVNLLGSFRCVC--P-RGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
C++ + ++C C P G + A C C G C+ +Y + C CP G
Sbjct: 806 CIDDVAGYKCNCLLPYTGATCEVVLAPCAP-SPCRNGGECR-QSEDYE-SFSCVCPTG 860
Score = 57.6 bits (133), Expect = 3e-08
Identities = 35/99 (35%), Positives = 46/99 (46%), Gaps = 2/99 (2%)
Frame = +3
Query: 111 CDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 290
CD L T Y C C G+ G +C+ D C + C E SY C C
Sbjct: 117 CDLL---TLTEYKCRCPPGWS----GKSCQQADPCASNPCANGGQCLPFEASYICHCPPS 169
Query: 291 YEKRGDAC-VDINECHEE-GVCPSPGRCVNLLGSFRCVC 401
+ G C D+NEC ++ G+C G C N +GS+RCVC
Sbjct: 170 FH--GPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVC 206
Score = 57.2 bits (132), Expect = 4e-08
Identities = 50/178 (28%), Positives = 69/178 (38%), Gaps = 11/178 (6%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTD----GSYDCLCRTGYELDEDG 188
G+ CVCG + G + + C P CH D Y C C G+ G
Sbjct: 42 GTEACVCGGAF--VGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFS----G 95
Query: 189 ANCRDVDECERDTHTCQQ--ICSN-TEGSYECSCEDGYEKRGDACVDINECHEEGVCPSP 359
C + T+ C+ C T Y+C C G+ G +C + C C +
Sbjct: 96 PLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWS--GKSCQQADPC-ASNPCANG 152
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQ-TGRCQ--APCRNYAGGYRCDC 521
G+C+ S+ C CP + G C D +EC Q G C+ C N G YRC C
Sbjct: 153 GQCLPFEASYICHCPPSF----HGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVC 206
Score = 52.4 bits (120), Expect = 1e-06
Identities = 51/187 (27%), Positives = 76/187 (40%), Gaps = 15/187 (8%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGR-DECAVRPPPCD----QLCHNTDGSYDCLCRTGYE 173
V+ +G + C C PG+ G G +EC PCD Q C + C CR G+
Sbjct: 1245 VDQVGGYSCTCPPGF--VGERCEGDVNECLSN--PCDARGTQNCVQRVNDFHCECRAGH- 1299
Query: 174 LDEDGANCRDV-DECE----RDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECH 335
G C V + C+ ++ TC + SNT + C C G+E G C D C
Sbjct: 1300 ---TGRRCESVINGCKGKPCKNGGTC-AVASNTARGFICKCPAGFE--GATCENDARTCG 1353
Query: 336 EEGVCPSPGRCVNLLGSFRCVCPRGYR----LDAEGARCVDRDECAQTGRCQAPCRNYAG 503
C + G C++ S C+C + + C+ + C G C+ + +
Sbjct: 1354 SLR-CLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEP--TSESP 1410
Query: 504 GYRCDCP 524
YRC CP
Sbjct: 1411 FYRCLCP 1417
Score = 35.5 bits (78), Expect = 0.12
Identities = 22/73 (30%), Positives = 29/73 (39%), Gaps = 6/73 (8%)
Frame = +3
Query: 330 CHEEG-VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQT-----GRCQAPCR 491
C + G C + G+C G+ CVC + G RC D + C T G C R
Sbjct: 24 CSQPGETCLNGGKCEAANGTEACVCGGAF----VGPRCQDPNPCLSTPCKNAGTCHVVDR 79
Query: 492 NYAGGYRCDCPVG 530
Y C C +G
Sbjct: 80 RGVADYACSCALG 92
>AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1,
translocation-associated (Drosophila) protein.
Length = 2555
Score = 87.4 bits (207), Expect = 3e-17
Identities = 54/175 (30%), Positives = 78/175 (44%), Gaps = 4/175 (2%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
+ +F C+C PGY +EC+ +P C + D +Y C C G G NC
Sbjct: 584 VATFTCLCRPGYT-GHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKG----TTGPNC 638
Query: 198 R-DVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRC 368
++D+C + C C + YEC+CE GY G C ++I+EC C + G C
Sbjct: 639 EINLDDCA--SSPCDSGTCLDKIDGYECACEPGYT--GSMCNINIDEC-AGNPCHNGGTC 693
Query: 369 VNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQAPCRNYAGGYRCDCPVG 530
+ + F C CP GY C+ +EC CR+ GY+CDC G
Sbjct: 694 EDGINGFTCRCPEGYH----DPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPG 744
Score = 83.8 bits (198), Expect = 4e-16
Identities = 61/180 (33%), Positives = 79/180 (43%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVR-GRDECAVRPPPCDQLCHNTDG--SYDCLCRTGYELDE 182
NT G +RC C GY +GR D+C RP PC TDG + C C G+
Sbjct: 886 NTHGGYRCHCQAGY--SGRNCETDIDDC--RPNPCHNGGSCTDGINTAFCDCLPGFR--- 938
Query: 183 DGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSP 359
G C D++EC D C++ SY C+C G+ G C + E C +
Sbjct: 939 -GTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFS--GIHCENNTPDCTESSCFNG 995
Query: 360 GRCVNLLGSFRCVCPRGYR---LDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
G CV+ + SF C+CP G+ + C D C G CQ C G YRC CP G
Sbjct: 996 GTCVDGINSFTCLCPPGFTGSYCQHDVNEC-DSQPCLHGGTCQDGC----GSYRCTCPQG 1050
Score = 83.4 bits (197), Expect = 5e-16
Identities = 53/177 (29%), Positives = 76/177 (42%), Gaps = 3/177 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+NT+GSF C C GY R +EC P D C + G + C+C GYE G
Sbjct: 430 INTLGSFECQCLQGYT-GPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYE----G 484
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
+C + DEC C + ++C C G+ G C D++EC C +
Sbjct: 485 VHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGF--TGHLCQYDVDEC-ASTPCKNGA 541
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
+C++ ++ CVC GY G C VD DEC C++ + C C G
Sbjct: 542 KCLDGPNTYTCVCTEGY----TGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPG 594
Score = 78.6 bits (185), Expect = 1e-14
Identities = 52/173 (30%), Positives = 73/173 (42%), Gaps = 4/173 (2%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 200
SF CVC G++ V +EC + P C NT G Y C C+ GY G NC
Sbjct: 852 SFSCVCPTGWQGQTCEV-DINECVLSPCRHGASCQNTHGGYRCHCQAGY----SGRNCET 906
Query: 201 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNL 377
D+D+C + C++ + C C G+ RG C DINEC + C + C +
Sbjct: 907 DIDDCRPNPCHNGGSCTDGINTAFCDCLPGF--RGTFCEEDINECASD-PCRNGANCTDC 963
Query: 378 LGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC--QAPCRNYAGGYRCDCPVG 530
+ S+ C CP G+ G C + C C + + C CP G
Sbjct: 964 VDSYTCTCPAGF----SGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPG 1012
Score = 77.0 bits (181), Expect = 4e-14
Identities = 58/180 (32%), Positives = 76/180 (42%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
NT G + CVC G+ D+CA CH+ S+ C C G G
Sbjct: 314 NTHGGYNCVCVNGWTGEDCS-ENIDDCASAACFHGATCHDRVASFYCECPHG----RTGL 368
Query: 192 NCRDVDECERDTHTCQQICSNT--EGSYECSCEDGYEKRGDACV-DINECH-EEGVCPSP 359
C D C + C G C+C GY G AC D++EC C
Sbjct: 369 LCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYT--GPACSQDVDECSLGANPCEHA 426
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
G+C+N LGSF C C +GY G RC +D +EC + CQ A C + G ++C C G
Sbjct: 427 GKCINTLGSFECQCLQGY----TGPRCEIDVNECV-SNPCQNDATCLDQIGEFQCICMPG 481
Score = 76.2 bits (179), Expect = 7e-14
Identities = 50/176 (28%), Positives = 80/176 (45%), Gaps = 5/176 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ I + C C PGY + + DECA P C + + C C GY D
Sbjct: 656 LDKIDGYECACEPGYTGSMCNI-NIDECAGNPCHNGGTCEDGINGFTCRCPEGY---HDP 711
Query: 189 ANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
+V+EC +++ C C ++ Y+C C+ G+ G C ++ NEC E C + G
Sbjct: 712 TCLSEVNEC--NSNPCVHGACRDSLNGYKCDCDPGWS--GTNCDINNNEC-ESNPCVNGG 766
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRC--QAPCRNYAGGYRCDC 521
C ++ + C C G+ G C + +ECA + C Q C + GY+C+C
Sbjct: 767 TCKDMTSGYVCTCREGF----SGPNCQTNINECA-SNPCLNQGTCIDDVAGYKCNC 817
Score = 75.8 bits (178), Expect = 1e-13
Identities = 48/151 (31%), Positives = 72/151 (47%), Gaps = 12/151 (7%)
Frame = +3
Query: 120 LCHNTDGSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYE 296
LC + ++ C C+ GY G+ C D VDEC C++ G Y C C GY
Sbjct: 1121 LCVDAGNTHHCRCQAGYT----GSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYH 1176
Query: 297 KRGDACVD-INECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDEC---- 458
G C + I+EC C + G C++L +++C CPRG +G C ++ D+C
Sbjct: 1177 --GVNCSEEIDECLSHP-CQNGGTCLDLPNTYKCSCPRG----TQGVHCEINVDDCNPPV 1229
Query: 459 ---AQTGRC--QAPCRNYAGGYRCDCPVGTV 536
+++ +C C + GGY C CP G V
Sbjct: 1230 DPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV 1260
Score = 74.5 bits (175), Expect = 2e-13
Identities = 53/181 (29%), Positives = 76/181 (41%), Gaps = 8/181 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNT-DGSYDCLCRTGYELDE 182
N +GS+RCVC + G R P PC C T D +++C C G+
Sbjct: 197 NEVGSYRCVCRATH--TGPNCE-RPYVPCSPSPCQNGGTCRPTGDVTHECACLPGF---- 249
Query: 183 DGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECH-EEGVCP 353
G NC + +D+C + C + +Y C C E G C D++EC C
Sbjct: 250 TGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPP--EWTGQYCTEDVDECQLMPNACQ 307
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ-APCRNYAGGYRCDCPV 527
+ G C N G + CVC G+ G C + D+CA A C + + C+CP
Sbjct: 308 NGGTCHNTHGGYNCVCVNGW----TGEDCSENIDDCASAACFHGATCHDRVASFYCECPH 363
Query: 528 G 530
G
Sbjct: 364 G 364
Score = 73.3 bits (172), Expect = 5e-13
Identities = 61/188 (32%), Positives = 78/188 (41%), Gaps = 14/188 (7%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
V+ I SF C+C PG+ +EC +P C + GSY C C GY G
Sbjct: 999 VDGINSFTCLCPPGFT-GSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYT----G 1053
Query: 189 ANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECH----EEGV- 347
NC++ V C+ C T Y C C G+ G C V C +GV
Sbjct: 1054 PNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWT--GLYCDVPSVSCEVAAQRQGVD 1111
Query: 348 ----CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ--APCRNYAGG 506
C G CV+ + C C GY G+ C D DEC+ + CQ A C +Y GG
Sbjct: 1112 VARLCQHGGLCVDAGNTHHCRCQAGY----TGSYCEDLVDECSPS-PCQNGATCTDYLGG 1166
Query: 507 YRCDCPVG 530
Y C C G
Sbjct: 1167 YSCKCVAG 1174
Score = 72.5 bits (170), Expect = 9e-13
Identities = 55/185 (29%), Positives = 76/185 (41%), Gaps = 11/185 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDE 182
V+ + ++ C C P + DEC + P C CHNT G Y+C+C G+
Sbjct: 273 VDGVNTYNCRCPPEWT-GQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGW---- 327
Query: 183 DGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYE----KRGDACVDINECHEEGV 347
G +C ++D+C C + S+ C C G DAC+ N C+E
Sbjct: 328 TGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACIS-NPCNEGSN 386
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECA-QTGRCQ--APCRNYAGGYRC 515
C + VN G C CP GY G C D DEC+ C+ C N G + C
Sbjct: 387 CDT--NPVN--GKAICTCPSGY----TGPACSQDVDECSLGANPCEHAGKCINTLGSFEC 438
Query: 516 DCPVG 530
C G
Sbjct: 439 QCLQG 443
Score = 71.7 bits (168), Expect = 2e-12
Identities = 54/179 (30%), Positives = 76/179 (42%), Gaps = 4/179 (2%)
Frame = +3
Query: 6 GVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
G+NT +F C C PG+R +ECA P C + SY C C G+
Sbjct: 925 GINT--AF-CDCLPGFRGTFCE-EDINECASDPCRNGANCTDCVDSYTCTCPAGFS---- 976
Query: 186 GANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSP 359
G +C + +C + C + S+ C C G+ G C D+NEC + C
Sbjct: 977 GIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFT--GSYCQHDVNECDSQP-CLHG 1033
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
G C + GS+RC CP+GY G C + + C+ C YRC+CP G
Sbjct: 1034 GTCQDGCGSYRCTCPQGY----TGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSG 1088
Score = 71.7 bits (168), Expect = 2e-12
Identities = 54/166 (32%), Positives = 76/166 (45%), Gaps = 17/166 (10%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTD--GSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQ--IC 248
DEC+ P PC TD G Y C C GY G NC ++DEC +H CQ C
Sbjct: 1147 DECS--PSPCQNGATCTDYLGGYSCKCVAGYH----GVNCSEEIDECL--SHPCQNGGTC 1198
Query: 249 SNTEGSYECSCEDGYEKRGDAC-VDINECHE--EGVCPSP-----GRCVNLLGSFRCVCP 404
+ +Y+CSC G +G C +++++C+ + V SP G CV+ +G + C CP
Sbjct: 1199 LDLPNTYKCSCPRG--TQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCP 1256
Query: 405 RGYRLDAEGARCV-DRDECAQT---GRCQAPCRNYAGGYRCDCPVG 530
G+ G RC D +EC R C + C+C G
Sbjct: 1257 PGF----VGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAG 1298
Score = 70.9 bits (166), Expect = 3e-12
Identities = 57/179 (31%), Positives = 78/179 (43%), Gaps = 10/179 (5%)
Frame = +3
Query: 24 SFRCVCGPGYR-PAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGAN 194
S+ C C P + P R + +EC +P C CHN GSY C+CR + G N
Sbjct: 161 SYICHCPPSFHGPTCR--QDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATH----TGPN 214
Query: 195 C-RDVDECERDTHTCQQICSNT-EGSYECSCEDGYEKRGDACVD-INECHEEGVCPSPGR 365
C R C C T + ++EC+C G+ G C + I++C C + G
Sbjct: 215 CERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGF--TGQNCEENIDDCPGNN-CKNGGA 271
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARCV-DRDEC-AQTGRCQ--APCRNYAGGYRCDCPVG 530
CV+ + ++ C CP + G C D DEC CQ C N GGY C C G
Sbjct: 272 CVDGVNTYNCRCPPEW----TGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNG 326
Score = 70.5 bits (165), Expect = 4e-12
Identities = 52/175 (29%), Positives = 78/175 (44%), Gaps = 6/175 (3%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCR 200
++ CVC GY V DEC P PC C + ++ CLCR GY G +C
Sbjct: 549 TYTCVCTEGYTGTHCEV-DIDECD--PDPCHYGSCKDGVATFTCLCRPGY----TGHHCE 601
Query: 201 -DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVN 374
+++EC C + + +Y C C G G C +++++C C S G C++
Sbjct: 602 TNINECSSQPCRHGGTCQDRDNAYLCFCLKG--TTGPNCEINLDDC-ASSPCDS-GTCLD 657
Query: 375 LLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
+ + C C GY G+ C ++ DECA C C + G+ C CP G
Sbjct: 658 KIDGYECACEPGY----TGSMCNINIDECA-GNPCHNGGTCEDGINGFTCRCPEG 707
Score = 64.9 bits (151), Expect = 2e-10
Identities = 52/186 (27%), Positives = 73/186 (39%), Gaps = 15/186 (8%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
+G + C C GY DEC P C + +Y C C G + G +C
Sbjct: 1164 LGGYSCKCVAGYHGVNCSEE-IDECLSHPCQNGGTCLDLPNTYKCSCPRGTQ----GVHC 1218
Query: 198 R-DVDECERDTHTCQQ--------ICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGV 347
+VD+C + C + G Y C+C G+ G+ C D+NEC
Sbjct: 1219 EINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV--GERCEGDVNECLSNP- 1275
Query: 348 CPSPG--RCVNLLGSFRCVCPRGY---RLDAEGARCVDRDECAQTGRCQAPCRNYAGGYR 512
C + G CV + F C C G+ R ++ C + C G C A N A G+
Sbjct: 1276 CDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKP-CKNGGTC-AVASNTARGFI 1333
Query: 513 CDCPVG 530
C CP G
Sbjct: 1334 CKCPAG 1339
Score = 60.1 bits (139), Expect = 5e-09
Identities = 41/140 (29%), Positives = 61/140 (43%), Gaps = 8/140 (5%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPC-DQLCHN----TDG--SYDCLCRTGYEL 176
+ S+ C C G+ G+ C P C + C N DG S+ CLC G+
Sbjct: 964 VDSYTCTCPAGFS----GIH----CENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFT- 1014
Query: 177 DEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCP 353
G+ C+ DV+EC+ C + GSY C+C GY G C ++ + C
Sbjct: 1015 ---GSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYT--GPNCQNLVHWCDSSPCK 1069
Query: 354 SPGRCVNLLGSFRCVCPRGY 413
+ G+C +RC CP G+
Sbjct: 1070 NGGKCWQTHTQYRCECPSGW 1089
Score = 59.7 bits (138), Expect = 7e-09
Identities = 49/178 (27%), Positives = 74/178 (41%), Gaps = 7/178 (3%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGAN 194
I F C C GY + +EC PC C ++ Y C C G+ G N
Sbjct: 697 INGFTCRCPEGYHDP-TCLSEVNEC--NSNPCVHGACRDSLNGYKCDCDPGWS----GTN 749
Query: 195 CRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGR 365
C D++ E +++ C C + Y C+C +G+ G C +INEC C + G
Sbjct: 750 C-DINNNECESNPCVNGGTCKDMTSGYVCTCREGFS--GPNCQTNINEC-ASNPCLNQGT 805
Query: 366 CVNLLGSFRCVC--P-RGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
C++ + ++C C P G + A C C G C+ +Y + C CP G
Sbjct: 806 CIDDVAGYKCNCLLPYTGATCEVVLAPCAP-SPCRNGGECR-QSEDYE-SFSCVCPTG 860
Score = 57.6 bits (133), Expect = 3e-08
Identities = 35/99 (35%), Positives = 46/99 (46%), Gaps = 2/99 (2%)
Frame = +3
Query: 111 CDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDG 290
CD L T Y C C G+ G +C+ D C + C E SY C C
Sbjct: 117 CDLL---TLTEYKCRCPPGWS----GKSCQQADPCASNPCANGGQCLPFEASYICHCPPS 169
Query: 291 YEKRGDAC-VDINECHEE-GVCPSPGRCVNLLGSFRCVC 401
+ G C D+NEC ++ G+C G C N +GS+RCVC
Sbjct: 170 FH--GPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVC 206
Score = 57.2 bits (132), Expect = 4e-08
Identities = 50/178 (28%), Positives = 69/178 (38%), Gaps = 11/178 (6%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTD----GSYDCLCRTGYELDEDG 188
G+ CVCG + G + + C P CH D Y C C G+ G
Sbjct: 42 GTEACVCGGAF--VGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFS----G 95
Query: 189 ANCRDVDECERDTHTCQQ--ICSN-TEGSYECSCEDGYEKRGDACVDINECHEEGVCPSP 359
C + T+ C+ C T Y+C C G+ G +C + C C +
Sbjct: 96 PLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWS--GKSCQQADPC-ASNPCANG 152
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQ-TGRCQ--APCRNYAGGYRCDC 521
G+C+ S+ C CP + G C D +EC Q G C+ C N G YRC C
Sbjct: 153 GQCLPFEASYICHCPPSF----HGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVC 206
Score = 52.4 bits (120), Expect = 1e-06
Identities = 51/187 (27%), Positives = 76/187 (40%), Gaps = 15/187 (8%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGR-DECAVRPPPCD----QLCHNTDGSYDCLCRTGYE 173
V+ +G + C C PG+ G G +EC PCD Q C + C CR G+
Sbjct: 1245 VDQVGGYSCTCPPGF--VGERCEGDVNECLSN--PCDARGTQNCVQRVNDFHCECRAGH- 1299
Query: 174 LDEDGANCRDV-DECE----RDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECH 335
G C V + C+ ++ TC + SNT + C C G+E G C D C
Sbjct: 1300 ---TGRRCESVINGCKGKPCKNGGTC-AVASNTARGFICKCPAGFE--GATCENDARTCG 1353
Query: 336 EEGVCPSPGRCVNLLGSFRCVCPRGYR----LDAEGARCVDRDECAQTGRCQAPCRNYAG 503
C + G C++ S C+C + + C+ + C G C+ + +
Sbjct: 1354 SLR-CLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEP--TSESP 1410
Query: 504 GYRCDCP 524
YRC CP
Sbjct: 1411 FYRCLCP 1417
Score = 35.5 bits (78), Expect = 0.12
Identities = 22/73 (30%), Positives = 29/73 (39%), Gaps = 6/73 (8%)
Frame = +3
Query: 330 CHEEG-VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQT-----GRCQAPCR 491
C + G C + G+C G+ CVC + G RC D + C T G C R
Sbjct: 24 CSQPGETCLNGGKCEAANGTEACVCGGAF----VGPRCQDPNPCLSTPCKNAGTCHVVDR 79
Query: 492 NYAGGYRCDCPVG 530
Y C C +G
Sbjct: 80 RGVADYACSCALG 92
>AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein
variant protein.
Length = 2067
Score = 87.4 bits (207), Expect = 3e-17
Identities = 54/175 (30%), Positives = 78/175 (44%), Gaps = 4/175 (2%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
+ +F C+C PGY +EC+ +P C + D +Y C C G G NC
Sbjct: 96 VATFTCLCRPGYT-GHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKG----TTGPNC 150
Query: 198 R-DVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRC 368
++D+C + C C + YEC+CE GY G C ++I+EC C + G C
Sbjct: 151 EINLDDCA--SSPCDSGTCLDKIDGYECACEPGYT--GSMCNINIDEC-AGNPCHNGGTC 205
Query: 369 VNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQAPCRNYAGGYRCDCPVG 530
+ + F C CP GY C+ +EC CR+ GY+CDC G
Sbjct: 206 EDGINGFTCRCPEGYH----DPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPG 256
Score = 83.8 bits (198), Expect = 4e-16
Identities = 61/180 (33%), Positives = 79/180 (43%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVR-GRDECAVRPPPCDQLCHNTDG--SYDCLCRTGYELDE 182
NT G +RC C GY +GR D+C RP PC TDG + C C G+
Sbjct: 398 NTHGGYRCHCQAGY--SGRNCETDIDDC--RPNPCHNGGSCTDGINTAFCDCLPGFR--- 450
Query: 183 DGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSP 359
G C D++EC D C++ SY C+C G+ G C + E C +
Sbjct: 451 -GTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFS--GIHCENNTPDCTESSCFNG 507
Query: 360 GRCVNLLGSFRCVCPRGYR---LDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
G CV+ + SF C+CP G+ + C D C G CQ C G YRC CP G
Sbjct: 508 GTCVDGINSFTCLCPPGFTGSYCQHDVNEC-DSQPCLHGGTCQDGC----GSYRCTCPQG 562
Score = 78.6 bits (185), Expect = 1e-14
Identities = 52/173 (30%), Positives = 73/173 (42%), Gaps = 4/173 (2%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 200
SF CVC G++ V +EC + P C NT G Y C C+ GY G NC
Sbjct: 364 SFSCVCPTGWQGQTCEV-DINECVLSPCRHGASCQNTHGGYRCHCQAGY----SGRNCET 418
Query: 201 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNL 377
D+D+C + C++ + C C G+ RG C DINEC + C + C +
Sbjct: 419 DIDDCRPNPCHNGGSCTDGINTAFCDCLPGF--RGTFCEEDINECASD-PCRNGANCTDC 475
Query: 378 LGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC--QAPCRNYAGGYRCDCPVG 530
+ S+ C CP G+ G C + C C + + C CP G
Sbjct: 476 VDSYTCTCPAGF----SGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPG 524
Score = 76.2 bits (179), Expect = 7e-14
Identities = 54/181 (29%), Positives = 79/181 (43%), Gaps = 5/181 (2%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVR-GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELD 179
R ++ I F+C C G+ G + DECA P C + +Y C+C GY
Sbjct: 16 RCLDKINEFQCECPTGF--TGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGY--- 70
Query: 180 EDGANCR-DVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVC 350
G +C D+DEC+ D C C + ++ C C GY G C +INEC + C
Sbjct: 71 -TGTHCEVDIDECDPD--PCHYGSCKDGVATFTCLCRPGY--TGHHCETNINECSSQ-PC 124
Query: 351 PSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQAPCRNYAGGYRCDCPV 527
G C + ++ C C +G G C ++ D+CA + C + GY C C
Sbjct: 125 RHGGTCQDRDNAYLCFCLKG----TTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEP 180
Query: 528 G 530
G
Sbjct: 181 G 181
Score = 76.2 bits (179), Expect = 7e-14
Identities = 50/176 (28%), Positives = 80/176 (45%), Gaps = 5/176 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ I + C C PGY + + DECA P C + + C C GY D
Sbjct: 168 LDKIDGYECACEPGYTGSMCNI-NIDECAGNPCHNGGTCEDGINGFTCRCPEGY---HDP 223
Query: 189 ANCRDVDECERDTHTC-QQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
+V+EC +++ C C ++ Y+C C+ G+ G C ++ NEC E C + G
Sbjct: 224 TCLSEVNEC--NSNPCVHGACRDSLNGYKCDCDPGWS--GTNCDINNNEC-ESNPCVNGG 278
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRC--QAPCRNYAGGYRCDC 521
C ++ + C C G+ G C + +ECA + C Q C + GY+C+C
Sbjct: 279 TCKDMTSGYVCTCREGF----SGPNCQTNINECA-SNPCLNQGTCIDDVAGYKCNC 329
Score = 75.8 bits (178), Expect = 1e-13
Identities = 48/151 (31%), Positives = 72/151 (47%), Gaps = 12/151 (7%)
Frame = +3
Query: 120 LCHNTDGSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYE 296
LC + ++ C C+ GY G+ C D VDEC C++ G Y C C GY
Sbjct: 633 LCVDAGNTHHCRCQAGYT----GSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYH 688
Query: 297 KRGDACVD-INECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDEC---- 458
G C + I+EC C + G C++L +++C CPRG +G C ++ D+C
Sbjct: 689 --GVNCSEEIDECLSHP-CQNGGTCLDLPNTYKCSCPRG----TQGVHCEINVDDCNPPV 741
Query: 459 ---AQTGRC--QAPCRNYAGGYRCDCPVGTV 536
+++ +C C + GGY C CP G V
Sbjct: 742 DPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV 772
Score = 73.3 bits (172), Expect = 5e-13
Identities = 61/188 (32%), Positives = 78/188 (41%), Gaps = 14/188 (7%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
V+ I SF C+C PG+ +EC +P C + GSY C C GY G
Sbjct: 511 VDGINSFTCLCPPGFT-GSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYT----G 565
Query: 189 ANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECH----EEGV- 347
NC++ V C+ C T Y C C G+ G C V C +GV
Sbjct: 566 PNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWT--GLYCDVPSVSCEVAAQRQGVD 623
Query: 348 ----CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ--APCRNYAGG 506
C G CV+ + C C GY G+ C D DEC+ + CQ A C +Y GG
Sbjct: 624 VARLCQHGGLCVDAGNTHHCRCQAGY----TGSYCEDLVDECSPS-PCQNGATCTDYLGG 678
Query: 507 YRCDCPVG 530
Y C C G
Sbjct: 679 YSCKCVAG 686
Score = 71.7 bits (168), Expect = 2e-12
Identities = 54/179 (30%), Positives = 76/179 (42%), Gaps = 4/179 (2%)
Frame = +3
Query: 6 GVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDED 185
G+NT +F C C PG+R +ECA P C + SY C C G+
Sbjct: 437 GINT--AF-CDCLPGFRGTFCE-EDINECASDPCRNGANCTDCVDSYTCTCPAGFS---- 488
Query: 186 GANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSP 359
G +C + +C + C + S+ C C G+ G C D+NEC + C
Sbjct: 489 GIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFT--GSYCQHDVNECDSQP-CLHG 545
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
G C + GS+RC CP+GY G C + + C+ C YRC+CP G
Sbjct: 546 GTCQDGCGSYRCTCPQGY----TGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSG 600
Score = 71.7 bits (168), Expect = 2e-12
Identities = 54/166 (32%), Positives = 76/166 (45%), Gaps = 17/166 (10%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTD--GSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQ--IC 248
DEC+ P PC TD G Y C C GY G NC ++DEC +H CQ C
Sbjct: 659 DECS--PSPCQNGATCTDYLGGYSCKCVAGYH----GVNCSEEIDECL--SHPCQNGGTC 710
Query: 249 SNTEGSYECSCEDGYEKRGDAC-VDINECHE--EGVCPSP-----GRCVNLLGSFRCVCP 404
+ +Y+CSC G +G C +++++C+ + V SP G CV+ +G + C CP
Sbjct: 711 LDLPNTYKCSCPRG--TQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCP 768
Query: 405 RGYRLDAEGARCV-DRDECAQT---GRCQAPCRNYAGGYRCDCPVG 530
G+ G RC D +EC R C + C+C G
Sbjct: 769 PGF----VGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAG 810
Score = 64.9 bits (151), Expect = 2e-10
Identities = 52/186 (27%), Positives = 73/186 (39%), Gaps = 15/186 (8%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
+G + C C GY DEC P C + +Y C C G + G +C
Sbjct: 676 LGGYSCKCVAGYHGVNCSEE-IDECLSHPCQNGGTCLDLPNTYKCSCPRGTQ----GVHC 730
Query: 198 R-DVDECERDTHTCQQ--------ICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGV 347
+VD+C + C + G Y C+C G+ G+ C D+NEC
Sbjct: 731 EINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV--GERCEGDVNECLSNP- 787
Query: 348 CPSPG--RCVNLLGSFRCVCPRGY---RLDAEGARCVDRDECAQTGRCQAPCRNYAGGYR 512
C + G CV + F C C G+ R ++ C + C G C A N A G+
Sbjct: 788 CDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKP-CKNGGTC-AVASNTARGFI 845
Query: 513 CDCPVG 530
C CP G
Sbjct: 846 CKCPAG 851
Score = 63.3 bits (147), Expect = 5e-10
Identities = 50/154 (32%), Positives = 69/154 (44%), Gaps = 4/154 (2%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNTE 260
DECA P + C + + C C TG+ G C+ DVDEC C +
Sbjct: 4 DECASSPCLHNGRCLDKINEFQCECPTGF----TGHLCQYDVDECASTPCKNGAKCLDGP 59
Query: 261 GSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGAR 437
+Y C C +GY G C VDI+EC + C G C + + +F C+C GY G
Sbjct: 60 NTYTCVCTEGY--TGTHCEVDIDEC-DPDPC-HYGSCKDGVATFTCLCRPGY----TGHH 111
Query: 438 C-VDRDEC-AQTGRCQAPCRNYAGGYRCDCPVGT 533
C + +EC +Q R C++ Y C C GT
Sbjct: 112 CETNINECSSQPCRHGGTCQDRDNAYLCFCLKGT 145
Score = 60.1 bits (139), Expect = 5e-09
Identities = 41/140 (29%), Positives = 61/140 (43%), Gaps = 8/140 (5%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPC-DQLCHN----TDG--SYDCLCRTGYEL 176
+ S+ C C G+ G+ C P C + C N DG S+ CLC G+
Sbjct: 476 VDSYTCTCPAGFS----GIH----CENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFT- 526
Query: 177 DEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCP 353
G+ C+ DV+EC+ C + GSY C+C GY G C ++ + C
Sbjct: 527 ---GSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYT--GPNCQNLVHWCDSSPCK 581
Query: 354 SPGRCVNLLGSFRCVCPRGY 413
+ G+C +RC CP G+
Sbjct: 582 NGGKCWQTHTQYRCECPSGW 601
Score = 59.7 bits (138), Expect = 7e-09
Identities = 49/178 (27%), Positives = 74/178 (41%), Gaps = 7/178 (3%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGAN 194
I F C C GY + +EC PC C ++ Y C C G+ G N
Sbjct: 209 INGFTCRCPEGYHDP-TCLSEVNEC--NSNPCVHGACRDSLNGYKCDCDPGWS----GTN 261
Query: 195 CRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGR 365
C D++ E +++ C C + Y C+C +G+ G C +INEC C + G
Sbjct: 262 C-DINNNECESNPCVNGGTCKDMTSGYVCTCREGFS--GPNCQTNINEC-ASNPCLNQGT 317
Query: 366 CVNLLGSFRCVC--P-RGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
C++ + ++C C P G + A C C G C+ +Y + C CP G
Sbjct: 318 CIDDVAGYKCNCLLPYTGATCEVVLAPCAP-SPCRNGGECR-QSEDYE-SFSCVCPTG 372
Score = 52.4 bits (120), Expect = 1e-06
Identities = 51/187 (27%), Positives = 76/187 (40%), Gaps = 15/187 (8%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGR-DECAVRPPPCD----QLCHNTDGSYDCLCRTGYE 173
V+ +G + C C PG+ G G +EC PCD Q C + C CR G+
Sbjct: 757 VDQVGGYSCTCPPGF--VGERCEGDVNECLSN--PCDARGTQNCVQRVNDFHCECRAGH- 811
Query: 174 LDEDGANCRDV-DECE----RDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECH 335
G C V + C+ ++ TC + SNT + C C G+E G C D C
Sbjct: 812 ---TGRRCESVINGCKGKPCKNGGTC-AVASNTARGFICKCPAGFE--GATCENDARTCG 865
Query: 336 EEGVCPSPGRCVNLLGSFRCVCPRGYR----LDAEGARCVDRDECAQTGRCQAPCRNYAG 503
C + G C++ S C+C + + C+ + C G C+ + +
Sbjct: 866 SLR-CLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEP--TSESP 922
Query: 504 GYRCDCP 524
YRC CP
Sbjct: 923 FYRCLCP 929
Score = 41.9 bits (94), Expect = 0.001
Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 2/74 (2%)
Frame = +3
Query: 315 VDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTG-RCQAPC 488
V+ +EC C GRC++ + F+C CP G+ G C D DECA T + A C
Sbjct: 1 VNTDEC-ASSPCLHNGRCLDKINEFQCECPTGF----TGHLCQYDVDECASTPCKNGAKC 55
Query: 489 RNYAGGYRCDCPVG 530
+ Y C C G
Sbjct: 56 LDGPNTYTCVCTEG 69
>M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein.
Length = 2444
Score = 85.8 bits (203), Expect = 9e-17
Identities = 54/175 (30%), Positives = 77/175 (44%), Gaps = 4/175 (2%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
+ +F C+C PGY +EC+ +P C + D +Y C C G G NC
Sbjct: 584 VATFTCLCRPGYT-GHHCETNINECSSQPCRLRGTCQDPDNAYLCFCLKG----TTGPNC 638
Query: 198 R-DVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRC 368
++D+C + C C + YEC+CE GY G C +I+EC C + G C
Sbjct: 639 EINLDDCA--SSPCDSGTCLDKIDGYECACEPGYT--GSMCNSNIDEC-AGNPCHNGGTC 693
Query: 369 VNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQAPCRNYAGGYRCDCPVG 530
+ + F C CP GY C+ +EC CR+ GY+CDC G
Sbjct: 694 EDGINGFTCRCPEGYH----DPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPG 744
Score = 83.4 bits (197), Expect = 5e-16
Identities = 53/177 (29%), Positives = 76/177 (42%), Gaps = 3/177 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+NT+GSF C C GY R +EC P D C + G + C+C GYE G
Sbjct: 430 INTLGSFECQCLQGYT-GPRCEIDVNECVSNPCQNDATCLDQIGEFQCMCMPGYE----G 484
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
+C + DEC C + ++C C G+ G C D++EC C +
Sbjct: 485 VHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGF--TGHLCQYDVDEC-ASTPCKNGA 541
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
+C++ ++ CVC GY G C VD DEC C++ + C C G
Sbjct: 542 KCLDGPNTYTCVCTEGY----TGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPG 594
Score = 77.0 bits (181), Expect = 4e-14
Identities = 58/180 (32%), Positives = 76/180 (42%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
NT G + CVC G+ D+CA CH+ S+ C C G G
Sbjct: 314 NTHGGYNCVCVNGWTGEDCS-ENIDDCASAACFHGATCHDRVASFYCECPHG----RTGL 368
Query: 192 NCRDVDECERDTHTCQQICSNT--EGSYECSCEDGYEKRGDACV-DINECH-EEGVCPSP 359
C D C + C G C+C GY G AC D++EC C
Sbjct: 369 LCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYT--GPACSQDVDECSLGANPCEHA 426
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
G+C+N LGSF C C +GY G RC +D +EC + CQ A C + G ++C C G
Sbjct: 427 GKCINTLGSFECQCLQGY----TGPRCEIDVNECV-SNPCQNDATCLDQIGEFQCMCMPG 481
Score = 75.8 bits (178), Expect = 1e-13
Identities = 48/151 (31%), Positives = 72/151 (47%), Gaps = 12/151 (7%)
Frame = +3
Query: 120 LCHNTDGSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYE 296
LC + ++ C C+ GY G+ C D VDEC C++ G Y C C GY
Sbjct: 1122 LCVDAGNTHHCRCQAGYT----GSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYH 1177
Query: 297 KRGDACVD-INECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDEC---- 458
G C + I+EC C + G C++L +++C CPRG +G C ++ D+C
Sbjct: 1178 --GVNCSEEIDECLSHP-CQNGGTCLDLPNTYKCSCPRG----TQGVHCEINVDDCNPPV 1230
Query: 459 ---AQTGRC--QAPCRNYAGGYRCDCPVGTV 536
+++ +C C + GGY C CP G V
Sbjct: 1231 DPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV 1261
Score = 75.4 bits (177), Expect = 1e-13
Identities = 58/179 (32%), Positives = 82/179 (45%), Gaps = 6/179 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGR-DECAVRPPPCDQLCHNTDG--SYDCLCRTGYELDE 182
NT G +RC C GY +GR D+C RP PC TDG + C C G+
Sbjct: 887 NTHGXYRCHCQAGY--SGRNCETDIDDC--RPNPCHNGGSCTDGINTAFCDCLPGFR--- 939
Query: 183 DGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSP 359
G C D++EC D C++ SY C+C G+ G C + E C +
Sbjct: 940 -GTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFS--GIHCENNTPDCTESSCFNG 996
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVD-RDEC-AQTGRCQAPCRNYAGGYRCDCPVG 530
G CV+ + SF C+CP G+ G+ C +EC ++ C++ G +RC CP G
Sbjct: 997 GTCVDGINSFTCLCPPGF----TGSYCQHVVNECDSRPCLLGGTCQDGRGLHRCTCPQG 1051
Score = 74.9 bits (176), Expect = 2e-13
Identities = 50/173 (28%), Positives = 69/173 (39%), Gaps = 4/173 (2%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 200
SF CVC +EC + P C NT G Y C C+ GY G NC
Sbjct: 852 SFSCVCPTAGAKGQTCEVDINECVLSPCRHGASCQNTHGXYRCHCQAGY----SGRNCET 907
Query: 201 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNL 377
D+D+C + C++ + C C G+ RG C DINEC + C + C +
Sbjct: 908 DIDDCRPNPCHNGGSCTDGINTAFCDCLPGF--RGTFCEEDINECASD-PCRNGANCTDC 964
Query: 378 LGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC--QAPCRNYAGGYRCDCPVG 530
+ S+ C CP G+ G C + C C + + C CP G
Sbjct: 965 VDSYTCTCPAGF----SGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPG 1013
Score = 74.5 bits (175), Expect = 2e-13
Identities = 53/181 (29%), Positives = 76/181 (41%), Gaps = 8/181 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNT-DGSYDCLCRTGYELDE 182
N +GS+RCVC + G R P PC C T D +++C C G+
Sbjct: 197 NEVGSYRCVCRATH--TGPNCE-RPYVPCSPSPCQNGGTCRPTGDVTHECACLPGF---- 249
Query: 183 DGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECH-EEGVCP 353
G NC + +D+C + C + +Y C C E G C D++EC C
Sbjct: 250 TGQNCEENIDDCPGNNCKNGGACVDGVNTYNCPCPP--EWTGQYCTEDVDECQLMPNACQ 307
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ-APCRNYAGGYRCDCPV 527
+ G C N G + CVC G+ G C + D+CA A C + + C+CP
Sbjct: 308 NGGTCHNTHGGYNCVCVNGW----TGEDCSENIDDCASAACFHGATCHDRVASFYCECPH 363
Query: 528 G 530
G
Sbjct: 364 G 364
Score = 72.9 bits (171), Expect = 7e-13
Identities = 55/185 (29%), Positives = 76/185 (41%), Gaps = 11/185 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDE 182
V+ + ++ C C P + DEC + P C CHNT G Y+C+C G+
Sbjct: 273 VDGVNTYNCPCPPEWT-GQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGW---- 327
Query: 183 DGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYE----KRGDACVDINECHEEGV 347
G +C ++D+C C + S+ C C G DAC+ N C+E
Sbjct: 328 TGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACIS-NPCNEGSN 386
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECA-QTGRCQ--APCRNYAGGYRC 515
C + VN G C CP GY G C D DEC+ C+ C N G + C
Sbjct: 387 CDT--NPVN--GKAICTCPSGY----TGPACSQDVDECSLGANPCEHAGKCINTLGSFEC 438
Query: 516 DCPVG 530
C G
Sbjct: 439 QCLQG 443
Score = 71.7 bits (168), Expect = 2e-12
Identities = 49/176 (27%), Positives = 78/176 (44%), Gaps = 5/176 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ I + C C PGY + DECA P C + + C C GY D
Sbjct: 656 LDKIDGYECACEPGYTGSMCN-SNIDECAGNPCHNGGTCEDGINGFTCRCPEGYH---DP 711
Query: 189 ANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
+V+EC +++ C C ++ Y+C C+ G+ G C ++ NEC E C + G
Sbjct: 712 TCLSEVNEC--NSNPCVHGACRDSLNGYKCDCDPGWS--GTNCDINNNEC-ESNPCVNGG 766
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRC--QAPCRNYAGGYRCDC 521
C ++ C C G+ G C + +ECA + C + C + GY+C+C
Sbjct: 767 TCKDMTSGIVCTCREGF----SGPNCQTNINECA-SNPCLNKGTCIDDVAGYKCNC 817
Score = 71.7 bits (168), Expect = 2e-12
Identities = 54/166 (32%), Positives = 76/166 (45%), Gaps = 17/166 (10%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTD--GSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQ--IC 248
DEC+ P PC TD G Y C C GY G NC ++DEC +H CQ C
Sbjct: 1148 DECS--PSPCQNGATCTDYLGGYSCKCVAGYH----GVNCSEEIDECL--SHPCQNGGTC 1199
Query: 249 SNTEGSYECSCEDGYEKRGDAC-VDINECHE--EGVCPSP-----GRCVNLLGSFRCVCP 404
+ +Y+CSC G +G C +++++C+ + V SP G CV+ +G + C CP
Sbjct: 1200 LDLPNTYKCSCPRG--TQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCP 1257
Query: 405 RGYRLDAEGARCV-DRDECAQT---GRCQAPCRNYAGGYRCDCPVG 530
G+ G RC D +EC R C + C+C G
Sbjct: 1258 PGF----VGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAG 1299
Score = 71.3 bits (167), Expect = 2e-12
Identities = 57/179 (31%), Positives = 78/179 (43%), Gaps = 10/179 (5%)
Frame = +3
Query: 24 SFRCVCGPGYR-PAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGAN 194
S+ C C P + P R + +EC +P C CHN GSY C+CR + G N
Sbjct: 161 SYICHCPPSFHGPTCR--QDVNECGQKPRLCRHGGTCHNEVGSYRCVCRATH----TGPN 214
Query: 195 C-RDVDECERDTHTCQQICSNT-EGSYECSCEDGYEKRGDACVD-INECHEEGVCPSPGR 365
C R C C T + ++EC+C G+ G C + I++C C + G
Sbjct: 215 CERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGF--TGQNCEENIDDCPGNN-CKNGGA 271
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARCV-DRDEC-AQTGRCQ--APCRNYAGGYRCDCPVG 530
CV+ + ++ C CP + G C D DEC CQ C N GGY C C G
Sbjct: 272 CVDGVNTYNCPCPPEW----TGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNG 326
Score = 70.9 bits (166), Expect = 3e-12
Identities = 52/175 (29%), Positives = 77/175 (44%), Gaps = 6/175 (3%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCR 200
++ CVC GY V DEC P PC C + ++ CLCR GY G +C
Sbjct: 549 TYTCVCTEGYTGTHCEV-DIDECD--PDPCHYGSCKDGVATFTCLCRPGY----TGHHCE 601
Query: 201 -DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVN 374
+++EC + C + + +Y C C G G C +++++C C S G C++
Sbjct: 602 TNINECSSQPCRLRGTCQDPDNAYLCFCLKG--TTGPNCEINLDDC-ASSPCDS-GTCLD 657
Query: 375 LLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ--APCRNYAGGYRCDCPVG 530
+ + C C GY G+ C DECA C C + G+ C CP G
Sbjct: 658 KIDGYECACEPGY----TGSMCNSNIDECA-GNPCHNGGTCEDGINGFTCRCPEG 707
Score = 70.9 bits (166), Expect = 3e-12
Identities = 60/188 (31%), Positives = 77/188 (40%), Gaps = 14/188 (7%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
V+ I SF C+C PG+ +EC RP C + G + C C GY G
Sbjct: 1000 VDGINSFTCLCPPGF-TGSYCQHVVNECDSRPCLLGGTCQDGRGLHRCTCPQGY----TG 1054
Query: 189 ANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINEC----HEEGV- 347
NC++ V C+ C T Y C C G+ G C V C +GV
Sbjct: 1055 PNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGW--TGLYCDVPSVSCEVAAQRQGVD 1112
Query: 348 ----CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ--APCRNYAGG 506
C G CV+ + C C GY G+ C D DEC+ + CQ A C +Y GG
Sbjct: 1113 VARLCQHGGLCVDAGNTHHCRCQAGY----TGSYCEDLVDECSPS-PCQNGATCTDYLGG 1167
Query: 507 YRCDCPVG 530
Y C C G
Sbjct: 1168 YSCKCVAG 1175
Score = 64.9 bits (151), Expect = 2e-10
Identities = 52/186 (27%), Positives = 73/186 (39%), Gaps = 15/186 (8%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
+G + C C GY DEC P C + +Y C C G + G +C
Sbjct: 1165 LGGYSCKCVAGYHGVNCSEE-IDECLSHPCQNGGTCLDLPNTYKCSCPRGTQ----GVHC 1219
Query: 198 R-DVDECERDTHTCQQ--------ICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGV 347
+VD+C + C + G Y C+C G+ G+ C D+NEC
Sbjct: 1220 EINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV--GERCEGDVNECLSNP- 1276
Query: 348 CPSPG--RCVNLLGSFRCVCPRGY---RLDAEGARCVDRDECAQTGRCQAPCRNYAGGYR 512
C + G CV + F C C G+ R ++ C + C G C A N A G+
Sbjct: 1277 CDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKP-CKNGGTC-AVASNTARGFI 1334
Query: 513 CDCPVG 530
C CP G
Sbjct: 1335 CKCPAG 1340
Score = 56.8 bits (131), Expect = 5e-08
Identities = 50/178 (28%), Positives = 69/178 (38%), Gaps = 11/178 (6%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTD----GSYDCLCRTGYELDEDG 188
G+ CVCG + G + + C P CH D Y C C G+ G
Sbjct: 42 GTEACVCGGAF--VGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFS----G 95
Query: 189 ANCRDVDECERDTHTCQQ--ICSN-TEGSYECSCEDGYEKRGDACVDINECHEEGVCPSP 359
C + T+ C+ C T Y+C C G+ G +C + C C +
Sbjct: 96 PLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWS--GKSCQQADPC-ASNPCANG 152
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGR-CQ--APCRNYAGGYRCDC 521
G+C+ S+ C CP + G C D +EC Q R C+ C N G YRC C
Sbjct: 153 GQCLPFEASYICHCPPSF----HGPTCRQDVNECGQKPRLCRHGGTCHNEVGSYRCVC 206
Score = 54.4 bits (125), Expect = 3e-07
Identities = 38/140 (27%), Positives = 59/140 (42%), Gaps = 8/140 (5%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPC-DQLCHN----TDG--SYDCLCRTGYEL 176
+ S+ C C G+ G+ C P C + C N DG S+ CLC G+
Sbjct: 965 VDSYTCTCPAGFS----GIH----CENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFT- 1015
Query: 177 DEDGANCRDV-DECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCP 353
G+ C+ V +EC+ C + G + C+C GY G C ++ + C
Sbjct: 1016 ---GSYCQHVVNECDSRPCLLGGTCQDGRGLHRCTCPQGYT--GPNCQNLVHWCDSSPCK 1070
Query: 354 SPGRCVNLLGSFRCVCPRGY 413
+ G+C +RC CP G+
Sbjct: 1071 NGGKCWQTHTQYRCECPSGW 1090
Score = 52.4 bits (120), Expect = 1e-06
Identities = 51/187 (27%), Positives = 76/187 (40%), Gaps = 15/187 (8%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGR-DECAVRPPPCD----QLCHNTDGSYDCLCRTGYE 173
V+ +G + C C PG+ G G +EC PCD Q C + C CR G+
Sbjct: 1246 VDQVGGYSCTCPPGF--VGERCEGDVNECLSN--PCDARGTQNCVQRVNDFHCECRAGH- 1300
Query: 174 LDEDGANCRDV-DECE----RDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECH 335
G C V + C+ ++ TC + SNT + C C G+E G C D C
Sbjct: 1301 ---TGRRCESVINGCKGKPCKNGGTC-AVASNTARGFICKCPAGFE--GATCENDARTCG 1354
Query: 336 EEGVCPSPGRCVNLLGSFRCVCPRGYR----LDAEGARCVDRDECAQTGRCQAPCRNYAG 503
C + G C++ S C+C + + C+ + C G C+ + +
Sbjct: 1355 SLR-CLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEP--TSESP 1411
Query: 504 GYRCDCP 524
YRC CP
Sbjct: 1412 FYRCLCP 1418
Score = 35.5 bits (78), Expect = 0.12
Identities = 22/73 (30%), Positives = 29/73 (39%), Gaps = 6/73 (8%)
Frame = +3
Query: 330 CHEEG-VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQT-----GRCQAPCR 491
C + G C + G+C G+ CVC + G RC D + C T G C R
Sbjct: 24 CSQPGETCLNGGKCEAANGTEACVCGGAF----VGPRCQDPNPCLSTPCKNAGTCHVVDR 79
Query: 492 NYAGGYRCDCPVG 530
Y C C +G
Sbjct: 80 RGVADYACSCALG 92
>AK123000-1|BAC85516.1| 1176|Homo sapiens 3 (HIVEP3). protein.
Length = 1176
Score = 85.8 bits (203), Expect = 9e-17
Identities = 62/172 (36%), Positives = 79/172 (45%), Gaps = 7/172 (4%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-D 203
FRC C PG++ R DECA RP C N Y+C C GY G C +
Sbjct: 92 FRCYCVPGFQ-GPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYA----GVTCETE 146
Query: 204 VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNLL 380
VDEC C + GS+ C C GY G C +D++EC + C G C +L+
Sbjct: 147 VDECASAPCLHGASCLDGVGSFRCVCAPGY--GGTRCQLDLDECQSQ-PCAHGGTCHDLV 203
Query: 381 GSFRCVCP-RGYRLDAEGARCVDRD--ECAQTGRCQ--APCRNYAGGYRCDC 521
FRC C GY EG C +R+ ECA + C+ A C G +RC C
Sbjct: 204 NGFRCDCAGTGY----EGTHC-EREVLECA-SAPCEHNASCLEGLGSFRCLC 249
Score = 81.0 bits (191), Expect = 3e-15
Identities = 70/197 (35%), Positives = 86/197 (43%), Gaps = 26/197 (13%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCR-TGYELDEDGAN 194
+GSFRCVC PGY R DEC +P CH+ + C C TGYE G +
Sbjct: 165 VGSFRCVCAPGY-GGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYE----GTH 219
Query: 195 C-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRC 368
C R+V EC C GS+ C C GY G+ C VD +EC C GRC
Sbjct: 220 CEREVLECASAPCEHNASCLEGLGSFRCLCWPGYS--GELCEVDEDEC-ASSPCQHGGRC 276
Query: 369 VN-----LLG----------SFR------CVCPRGYRLDAEGARC-VDRDECAQTGRCQ- 479
+ L G SFR C CP G+ EGA C V+ DECA
Sbjct: 277 LQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGF----EGADCGVEVDECASRPCLNG 332
Query: 480 APCRNYAGGYRCDCPVG 530
C++ G++C CP G
Sbjct: 333 GHCQDLPNGFQCHCPDG 349
Score = 66.9 bits (156), Expect = 4e-11
Identities = 45/133 (33%), Positives = 57/133 (42%), Gaps = 5/133 (3%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-D 203
F C C PG+ A GV DECA RP C + + C C GY G C D
Sbjct: 304 FLCHCPPGFEGADCGVEV-DECASRPCLNGGHCQDLPNGFQCHCPDGYA----GPTCEED 358
Query: 204 VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNL-- 377
VDEC D CS+T Y C C + + R D V + C + CP C+ +
Sbjct: 359 VDECLSDPCLHGGTCSDTVAGYICRCPETWGGR-DCSVQLTGC-QGHTCPLAATCIPIFE 416
Query: 378 --LGSFRCVCPRG 410
+ S+ C CP G
Sbjct: 417 SGVHSYVCHCPPG 429
Score = 63.3 bits (147), Expect = 5e-10
Identities = 58/190 (30%), Positives = 76/190 (40%), Gaps = 21/190 (11%)
Frame = +3
Query: 18 IGSFRCVC-GPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGY-----ELD 179
+ FRC C G GY R ECA P + C GS+ CLC GY E+D
Sbjct: 203 VNGFRCDCAGTGYEGT-HCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVD 261
Query: 180 ED---GANCRDVDEC--ERDTHTCQQICSNTEGSYE--------CSCEDGYEKRGDACVD 320
ED + C+ C D + + G++ C C G+E D V+
Sbjct: 262 EDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEG-ADCGVE 320
Query: 321 INECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ-APCRN 494
++EC C + G C +L F+C CP GY G C D DEC C +
Sbjct: 321 VDECASRP-CLNGGHCQDLPNGFQCHCPDGY----AGPTCEEDVDECLSDPCLHGGTCSD 375
Query: 495 YAGGYRCDCP 524
GY C CP
Sbjct: 376 TVAGYICRCP 385
Score = 50.8 bits (116), Expect = 3e-06
Identities = 39/99 (39%), Positives = 44/99 (44%), Gaps = 4/99 (4%)
Frame = +3
Query: 246 CSNTE-GSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLD 422
C TE G Y C E RG A CH +C G N FRC C G+
Sbjct: 53 CQATESGGYTCG---PMEPRGCAT---QPCHHGALCVPQGPDPN---GFRCYCVPGF--- 100
Query: 423 AEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
+G RC +D DECA C A CRN A Y C CP+G
Sbjct: 101 -QGPRCELDIDECASRP-CHHGATCRNLADRYECHCPLG 137
Score = 39.1 bits (87), Expect = 0.010
Identities = 26/86 (30%), Positives = 36/86 (41%), Gaps = 3/86 (3%)
Frame = +3
Query: 45 PGYRPAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCR-DVDEC 215
PG G RG CA P PC D C + ++ C C G+E G C VD C
Sbjct: 1045 PGTPAPILGCRGAPVCA--PSPCLHDGACRDLFDAFACACGPGWE----GPRCEAHVDPC 1098
Query: 216 ERDTHTCQQICSNTEGSYECSCEDGY 293
+ ++ +G +EC C G+
Sbjct: 1099 HSAPCARGRCHTHPDGRFECRCPPGF 1124
Score = 37.1 bits (82), Expect = 0.041
Identities = 25/74 (33%), Positives = 31/74 (41%), Gaps = 7/74 (9%)
Frame = +3
Query: 330 CHEEGVC-PSP----GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQAPCR 491
C VC PSP G C +L +F C C G+ EG RC D C + C
Sbjct: 1054 CRGAPVCAPSPCLHDGACRDLFDAFACACGPGW----EGPRCEAHVDPCHSAPCARGRCH 1109
Query: 492 NYAGG-YRCDCPVG 530
+ G + C CP G
Sbjct: 1110 THPDGRFECRCPPG 1123
Score = 34.7 bits (76), Expect = 0.22
Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 2/75 (2%)
Frame = +3
Query: 195 CRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRC- 368
CR C C + ++ C+C G+E G C ++ CH C + GRC
Sbjct: 1054 CRGAPVCAPSPCLHDGACRDLFDAFACACGPGWE--GPRCEAHVDPCH-SAPC-ARGRCH 1109
Query: 369 VNLLGSFRCVCPRGY 413
+ G F C CP G+
Sbjct: 1110 THPDGRFECRCPPGF 1124
Score = 33.1 bits (72), Expect = 0.67
Identities = 21/61 (34%), Positives = 28/61 (45%), Gaps = 2/61 (3%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCH-NTDGSYDCLCRTGYELDEDGANC 197
+F C CGPG+ R D C PC + CH + DG ++C C G+ G C
Sbjct: 1077 AFACACGPGWE-GPRCEAHVDPC--HSAPCARGRCHTHPDGRFECRCPPGF----GGPRC 1129
Query: 198 R 200
R
Sbjct: 1130 R 1130
Score = 30.7 bits (66), Expect = 3.6
Identities = 18/46 (39%), Positives = 20/46 (43%)
Frame = +3
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP 485
C G CV+L FRC C R +R G C D A G AP
Sbjct: 614 CVHGGSCVDLWTHFRCDCARPHR----GPTCADEIPAATFGLGGAP 655
>AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein.
Length = 2556
Score = 85.8 bits (203), Expect = 9e-17
Identities = 54/175 (30%), Positives = 77/175 (44%), Gaps = 4/175 (2%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
+ +F C+C PGY +EC+ +P C + D +Y C C G G NC
Sbjct: 584 VATFTCLCRPGYT-GHHCETNINECSSQPCRLRGTCQDPDNAYLCFCLKG----TTGPNC 638
Query: 198 R-DVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRC 368
++D+C + C C + YEC+CE GY G C +I+EC C + G C
Sbjct: 639 EINLDDCA--SSPCDSGTCLDKIDGYECACEPGYT--GSMCNSNIDEC-AGNPCHNGGTC 693
Query: 369 VNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQAPCRNYAGGYRCDCPVG 530
+ + F C CP GY C+ +EC CR+ GY+CDC G
Sbjct: 694 EDGINGFTCRCPEGYH----DPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPG 744
Score = 83.4 bits (197), Expect = 5e-16
Identities = 53/177 (29%), Positives = 76/177 (42%), Gaps = 3/177 (1%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
+NT+GSF C C GY R +EC P D C + G + C+C GYE G
Sbjct: 430 INTLGSFECQCLQGYT-GPRCEIDVNECVSNPCQNDATCLDQIGEFQCMCMPGYE----G 484
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
+C + DEC C + ++C C G+ G C D++EC C +
Sbjct: 485 VHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGF--TGHLCQYDVDEC-ASTPCKNGA 541
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
+C++ ++ CVC GY G C VD DEC C++ + C C G
Sbjct: 542 KCLDGPNTYTCVCTEGY----TGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPG 594
Score = 77.0 bits (181), Expect = 4e-14
Identities = 58/180 (32%), Positives = 76/180 (42%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
NT G + CVC G+ D+CA CH+ S+ C C G G
Sbjct: 314 NTHGGYNCVCVNGWTGEDCS-ENIDDCASAACFHGATCHDRVASFYCECPHG----RTGL 368
Query: 192 NCRDVDECERDTHTCQQICSNT--EGSYECSCEDGYEKRGDACV-DINECH-EEGVCPSP 359
C D C + C G C+C GY G AC D++EC C
Sbjct: 369 LCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYT--GPACSQDVDECSLGANPCEHA 426
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
G+C+N LGSF C C +GY G RC +D +EC + CQ A C + G ++C C G
Sbjct: 427 GKCINTLGSFECQCLQGY----TGPRCEIDVNECV-SNPCQNDATCLDQIGEFQCMCMPG 481
Score = 75.8 bits (178), Expect = 1e-13
Identities = 48/151 (31%), Positives = 72/151 (47%), Gaps = 12/151 (7%)
Frame = +3
Query: 120 LCHNTDGSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYE 296
LC + ++ C C+ GY G+ C D VDEC C++ G Y C C GY
Sbjct: 1122 LCVDAGNTHHCRCQAGYT----GSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYH 1177
Query: 297 KRGDACVD-INECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDEC---- 458
G C + I+EC C + G C++L +++C CPRG +G C ++ D+C
Sbjct: 1178 --GVNCSEEIDECLSHP-CQNGGTCLDLPNTYKCSCPRG----TQGVHCEINVDDCNPPV 1230
Query: 459 ---AQTGRC--QAPCRNYAGGYRCDCPVGTV 536
+++ +C C + GGY C CP G V
Sbjct: 1231 DPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV 1261
Score = 75.4 bits (177), Expect = 1e-13
Identities = 58/179 (32%), Positives = 82/179 (45%), Gaps = 6/179 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGR-DECAVRPPPCDQLCHNTDG--SYDCLCRTGYELDE 182
NT G +RC C GY +GR D+C RP PC TDG + C C G+
Sbjct: 887 NTHGXYRCHCQAGY--SGRNCETDIDDC--RPNPCHNGGSCTDGINTAFCDCLPGFR--- 939
Query: 183 DGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSP 359
G C D++EC D C++ SY C+C G+ G C + E C +
Sbjct: 940 -GTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFS--GIHCENNTPDCTESSCFNG 996
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVD-RDEC-AQTGRCQAPCRNYAGGYRCDCPVG 530
G CV+ + SF C+CP G+ G+ C +EC ++ C++ G +RC CP G
Sbjct: 997 GTCVDGINSFTCLCPPGF----TGSYCQHVVNECDSRPCLLGGTCQDGRGLHRCTCPQG 1051
Score = 74.9 bits (176), Expect = 2e-13
Identities = 50/173 (28%), Positives = 69/173 (39%), Gaps = 4/173 (2%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR- 200
SF CVC +EC + P C NT G Y C C+ GY G NC
Sbjct: 852 SFSCVCPTAGAKGQTCEVDINECVLSPCRHGASCQNTHGXYRCHCQAGY----SGRNCET 907
Query: 201 DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNL 377
D+D+C + C++ + C C G+ RG C DINEC + C + C +
Sbjct: 908 DIDDCRPNPCHNGGSCTDGINTAFCDCLPGF--RGTFCEEDINECASD-PCRNGANCTDC 964
Query: 378 LGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC--QAPCRNYAGGYRCDCPVG 530
+ S+ C CP G+ G C + C C + + C CP G
Sbjct: 965 VDSYTCTCPAGF----SGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPG 1013
Score = 74.5 bits (175), Expect = 2e-13
Identities = 53/181 (29%), Positives = 76/181 (41%), Gaps = 8/181 (4%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNT-DGSYDCLCRTGYELDE 182
N +GS+RCVC + G R P PC C T D +++C C G+
Sbjct: 197 NEVGSYRCVCRATH--TGPNCE-RPYVPCSPSPCQNGGTCRPTGDVTHECACLPGF---- 249
Query: 183 DGANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECH-EEGVCP 353
G NC + +D+C + C + +Y C C E G C D++EC C
Sbjct: 250 TGQNCEENIDDCPGNNCKNGGACVDGVNTYNCPCPP--EWTGQYCTEDVDECQLMPNACQ 307
Query: 354 SPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ-APCRNYAGGYRCDCPV 527
+ G C N G + CVC G+ G C + D+CA A C + + C+CP
Sbjct: 308 NGGTCHNTHGGYNCVCVNGW----TGEDCSENIDDCASAACFHGATCHDRVASFYCECPH 363
Query: 528 G 530
G
Sbjct: 364 G 364
Score = 72.9 bits (171), Expect = 7e-13
Identities = 55/185 (29%), Positives = 76/185 (41%), Gaps = 11/185 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDE 182
V+ + ++ C C P + DEC + P C CHNT G Y+C+C G+
Sbjct: 273 VDGVNTYNCPCPPEWT-GQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGW---- 327
Query: 183 DGANC-RDVDECERDTHTCQQICSNTEGSYECSCEDGYE----KRGDACVDINECHEEGV 347
G +C ++D+C C + S+ C C G DAC+ N C+E
Sbjct: 328 TGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACIS-NPCNEGSN 386
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECA-QTGRCQ--APCRNYAGGYRC 515
C + VN G C CP GY G C D DEC+ C+ C N G + C
Sbjct: 387 CDT--NPVN--GKAICTCPSGY----TGPACSQDVDECSLGANPCEHAGKCINTLGSFEC 438
Query: 516 DCPVG 530
C G
Sbjct: 439 QCLQG 443
Score = 71.7 bits (168), Expect = 2e-12
Identities = 49/176 (27%), Positives = 78/176 (44%), Gaps = 5/176 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ I + C C PGY + DECA P C + + C C GY D
Sbjct: 656 LDKIDGYECACEPGYTGSMCN-SNIDECAGNPCHNGGTCEDGINGFTCRCPEGYH---DP 711
Query: 189 ANCRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
+V+EC +++ C C ++ Y+C C+ G+ G C ++ NEC E C + G
Sbjct: 712 TCLSEVNEC--NSNPCVHGACRDSLNGYKCDCDPGWS--GTNCDINNNEC-ESNPCVNGG 766
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRC--QAPCRNYAGGYRCDC 521
C ++ C C G+ G C + +ECA + C + C + GY+C+C
Sbjct: 767 TCKDMTSGIVCTCREGF----SGPNCQTNINECA-SNPCLNKGTCIDDVAGYKCNC 817
Score = 71.7 bits (168), Expect = 2e-12
Identities = 54/166 (32%), Positives = 76/166 (45%), Gaps = 17/166 (10%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTD--GSYDCLCRTGYELDEDGANC-RDVDECERDTHTCQQ--IC 248
DEC+ P PC TD G Y C C GY G NC ++DEC +H CQ C
Sbjct: 1148 DECS--PSPCQNGATCTDYLGGYSCKCVAGYH----GVNCSEEIDECL--SHPCQNGGTC 1199
Query: 249 SNTEGSYECSCEDGYEKRGDAC-VDINECHE--EGVCPSP-----GRCVNLLGSFRCVCP 404
+ +Y+CSC G +G C +++++C+ + V SP G CV+ +G + C CP
Sbjct: 1200 LDLPNTYKCSCPRG--TQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCP 1257
Query: 405 RGYRLDAEGARCV-DRDECAQT---GRCQAPCRNYAGGYRCDCPVG 530
G+ G RC D +EC R C + C+C G
Sbjct: 1258 PGF----VGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAG 1299
Score = 71.3 bits (167), Expect = 2e-12
Identities = 57/179 (31%), Positives = 78/179 (43%), Gaps = 10/179 (5%)
Frame = +3
Query: 24 SFRCVCGPGYR-PAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGAN 194
S+ C C P + P R + +EC +P C CHN GSY C+CR + G N
Sbjct: 161 SYICHCPPSFHGPTCR--QDVNECGQKPRLCRHGGTCHNEVGSYRCVCRATH----TGPN 214
Query: 195 C-RDVDECERDTHTCQQICSNT-EGSYECSCEDGYEKRGDACVD-INECHEEGVCPSPGR 365
C R C C T + ++EC+C G+ G C + I++C C + G
Sbjct: 215 CERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGF--TGQNCEENIDDCPGNN-CKNGGA 271
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARCV-DRDEC-AQTGRCQ--APCRNYAGGYRCDCPVG 530
CV+ + ++ C CP + G C D DEC CQ C N GGY C C G
Sbjct: 272 CVDGVNTYNCPCPPEW----TGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNG 326
Score = 70.9 bits (166), Expect = 3e-12
Identities = 52/175 (29%), Positives = 77/175 (44%), Gaps = 6/175 (3%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCR 200
++ CVC GY V DEC P PC C + ++ CLCR GY G +C
Sbjct: 549 TYTCVCTEGYTGTHCEV-DIDECD--PDPCHYGSCKDGVATFTCLCRPGY----TGHHCE 601
Query: 201 -DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVN 374
+++EC + C + + +Y C C G G C +++++C C S G C++
Sbjct: 602 TNINECSSQPCRLRGTCQDPDNAYLCFCLKG--TTGPNCEINLDDC-ASSPCDS-GTCLD 657
Query: 375 LLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ--APCRNYAGGYRCDCPVG 530
+ + C C GY G+ C DECA C C + G+ C CP G
Sbjct: 658 KIDGYECACEPGY----TGSMCNSNIDECA-GNPCHNGGTCEDGINGFTCRCPEG 707
Score = 70.9 bits (166), Expect = 3e-12
Identities = 60/188 (31%), Positives = 77/188 (40%), Gaps = 14/188 (7%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
V+ I SF C+C PG+ +EC RP C + G + C C GY G
Sbjct: 1000 VDGINSFTCLCPPGF-TGSYCQHVVNECDSRPCLLGGTCQDGRGLHRCTCPQGY----TG 1054
Query: 189 ANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINEC----HEEGV- 347
NC++ V C+ C T Y C C G+ G C V C +GV
Sbjct: 1055 PNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGW--TGLYCDVPSVSCEVAAQRQGVD 1112
Query: 348 ----CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ--APCRNYAGG 506
C G CV+ + C C GY G+ C D DEC+ + CQ A C +Y GG
Sbjct: 1113 VARLCQHGGLCVDAGNTHHCRCQAGY----TGSYCEDLVDECSPS-PCQNGATCTDYLGG 1167
Query: 507 YRCDCPVG 530
Y C C G
Sbjct: 1168 YSCKCVAG 1175
Score = 64.9 bits (151), Expect = 2e-10
Identities = 52/186 (27%), Positives = 73/186 (39%), Gaps = 15/186 (8%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
+G + C C GY DEC P C + +Y C C G + G +C
Sbjct: 1165 LGGYSCKCVAGYHGVNCSEE-IDECLSHPCQNGGTCLDLPNTYKCSCPRGTQ----GVHC 1219
Query: 198 R-DVDECERDTHTCQQ--------ICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGV 347
+VD+C + C + G Y C+C G+ G+ C D+NEC
Sbjct: 1220 EINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV--GERCEGDVNECLSNP- 1276
Query: 348 CPSPG--RCVNLLGSFRCVCPRGY---RLDAEGARCVDRDECAQTGRCQAPCRNYAGGYR 512
C + G CV + F C C G+ R ++ C + C G C A N A G+
Sbjct: 1277 CDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKP-CKNGGTC-AVASNTARGFI 1334
Query: 513 CDCPVG 530
C CP G
Sbjct: 1335 CKCPAG 1340
Score = 56.8 bits (131), Expect = 5e-08
Identities = 50/178 (28%), Positives = 69/178 (38%), Gaps = 11/178 (6%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTD----GSYDCLCRTGYELDEDG 188
G+ CVCG + G + + C P CH D Y C C G+ G
Sbjct: 42 GTEACVCGGAF--VGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFS----G 95
Query: 189 ANCRDVDECERDTHTCQQ--ICSN-TEGSYECSCEDGYEKRGDACVDINECHEEGVCPSP 359
C + T+ C+ C T Y+C C G+ G +C + C C +
Sbjct: 96 PLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWS--GKSCQQADPC-ASNPCANG 152
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGR-CQ--APCRNYAGGYRCDC 521
G+C+ S+ C CP + G C D +EC Q R C+ C N G YRC C
Sbjct: 153 GQCLPFEASYICHCPPSF----HGPTCRQDVNECGQKPRLCRHGGTCHNEVGSYRCVC 206
Score = 54.4 bits (125), Expect = 3e-07
Identities = 38/140 (27%), Positives = 59/140 (42%), Gaps = 8/140 (5%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPC-DQLCHN----TDG--SYDCLCRTGYEL 176
+ S+ C C G+ G+ C P C + C N DG S+ CLC G+
Sbjct: 965 VDSYTCTCPAGFS----GIH----CENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFT- 1015
Query: 177 DEDGANCRDV-DECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCP 353
G+ C+ V +EC+ C + G + C+C GY G C ++ + C
Sbjct: 1016 ---GSYCQHVVNECDSRPCLLGGTCQDGRGLHRCTCPQGYT--GPNCQNLVHWCDSSPCK 1070
Query: 354 SPGRCVNLLGSFRCVCPRGY 413
+ G+C +RC CP G+
Sbjct: 1071 NGGKCWQTHTQYRCECPSGW 1090
Score = 52.4 bits (120), Expect = 1e-06
Identities = 51/187 (27%), Positives = 76/187 (40%), Gaps = 15/187 (8%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGR-DECAVRPPPCD----QLCHNTDGSYDCLCRTGYE 173
V+ +G + C C PG+ G G +EC PCD Q C + C CR G+
Sbjct: 1246 VDQVGGYSCTCPPGF--VGERCEGDVNECLSN--PCDARGTQNCVQRVNDFHCECRAGH- 1300
Query: 174 LDEDGANCRDV-DECE----RDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECH 335
G C V + C+ ++ TC + SNT + C C G+E G C D C
Sbjct: 1301 ---TGRRCESVINGCKGKPCKNGGTC-AVASNTARGFICKCPAGFE--GATCENDARTCG 1354
Query: 336 EEGVCPSPGRCVNLLGSFRCVCPRGYR----LDAEGARCVDRDECAQTGRCQAPCRNYAG 503
C + G C++ S C+C + + C+ + C G C+ + +
Sbjct: 1355 SLR-CLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEP--TSESP 1411
Query: 504 GYRCDCP 524
YRC CP
Sbjct: 1412 FYRCLCP 1418
Score = 35.5 bits (78), Expect = 0.12
Identities = 22/73 (30%), Positives = 29/73 (39%), Gaps = 6/73 (8%)
Frame = +3
Query: 330 CHEEG-VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQT-----GRCQAPCR 491
C + G C + G+C G+ CVC + G RC D + C T G C R
Sbjct: 24 CSQPGETCLNGGKCEAANGTEACVCGGAF----VGPRCQDPNPCLSTPCKNAGTCHVVDR 79
Query: 492 NYAGGYRCDCPVG 530
Y C C +G
Sbjct: 80 RGVADYACSCALG 92
>U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein.
Length = 2321
Score = 85.4 bits (202), Expect = 1e-16
Identities = 58/179 (32%), Positives = 82/179 (45%), Gaps = 4/179 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ IG F C+C G+ V DEC P +C + + C C +G+ G
Sbjct: 447 LDRIGQFTCICMAGFTGTYCEV-DIDECQSSPCVNGGVCKDRVNGFSCTCPSGFS----G 501
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSPG 362
+ C+ DVDEC C + YEC C +G+E G C ++++C + C G
Sbjct: 502 STCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFE--GTLCDRNVDDCSPDP-CHH-G 557
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDR-DEC-AQTGRCQAPCRNYAGGYRCDCPVGT 533
RCV+ + SF C C GY G RC + DEC +Q R C + Y C CP GT
Sbjct: 558 RCVDGIASFSCACAPGY----TGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGT 612
Score = 83.4 bits (197), Expect = 5e-16
Identities = 64/185 (34%), Positives = 81/185 (43%), Gaps = 11/185 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNT-DGSYDCLCRTGYELD 179
+NT GSFRC C GY CA P PC C + D +YDC C G+E
Sbjct: 175 LNTPGSFRCQCPAGYT-GPLCENPAVPCA--PSPCRNGGTCRQSGDLTYDCACLPGFE-- 229
Query: 180 EDGANCR-DVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACV-DINECH-EEG 344
G NC +VD+C H C C + +Y C C E G C D++EC +
Sbjct: 230 --GQNCEVNVDDCPG--HRCLNGGTCVDGVNTYNCQCPP--EWTGQFCTEDVDECQLQPN 283
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRC--QAPCRNYAGGYRC 515
C + G C N LG CVC G+ G C D+CA T C A C + + C
Sbjct: 284 ACHNGGTCFNTLGGHSCVCVNGW----TGESCSQNIDDCA-TAVCFHGATCHDRVASFYC 338
Query: 516 DCPVG 530
CP+G
Sbjct: 339 ACPMG 343
Score = 81.4 bits (192), Expect = 2e-15
Identities = 58/179 (32%), Positives = 78/179 (43%), Gaps = 3/179 (1%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
R V+ I SF C C PGY R DEC +P C + Y C C +G
Sbjct: 558 RCVDGIASFSCACAPGYTGT-RCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSG----T 612
Query: 183 DGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPS 356
G NC ++D+C + T +C + Y+C C+ G+ G C V+INEC C
Sbjct: 613 TGVNCEVNIDDCASNPCTFG-VCRDGINRYDCVCQPGFT--GPLCNVEINEC-ASSPCGE 668
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE-CAQTGRCQAPCRNYAGGYRCDCPVG 530
G CV+ FRC+CP G + C+ CA C + GG+RC C G
Sbjct: 669 GGSCVDGENGFRCLCPPG----SLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPG 723
Score = 81.0 bits (191), Expect = 3e-15
Identities = 53/180 (29%), Positives = 77/180 (42%), Gaps = 4/180 (2%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
R VNT GSF C CG GY R +EC P C + G + C+C G+
Sbjct: 407 RCVNTQGSFLCQCGRGY-TGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGF---- 461
Query: 183 DGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPS 356
G C D+DEC+ +C + + C+C G+ G C +D++EC C +
Sbjct: 462 TGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFS--GSTCQLDVDEC-ASTPCRN 518
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDR--DECAQTGRCQAPCRNYAGGYRCDCPVG 530
+CV+ + C C G+ EG C DR D+C+ C + + C C G
Sbjct: 519 GAKCVDQPDGYECRCAEGF----EGTLC-DRNVDDCSPDPCHHGRCVDGIASFSCACAPG 573
Score = 80.2 bits (189), Expect = 4e-15
Identities = 61/180 (33%), Positives = 77/180 (42%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
NT+G CVC G+ + D+CA CH+ S+ C C G + G
Sbjct: 293 NTLGGHSCVCVNGWTGESCS-QNIDDCATAVCFHGATCHDRVASFYCACPMG----KTGL 347
Query: 192 NCRDVDECERDTHTCQQICSNT--EGSYECSCEDGYEKRGDAC-VDINECH-EEGVCPSP 359
C D C + IC G C+C G+ G AC D++EC C
Sbjct: 348 LCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFT--GGACDQDVDECSIGANPCEHL 405
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRC--QAPCRNYAGGYRCDCPVG 530
GRCVN GSF C C RGY G RC D +EC +G C QA C + G + C C G
Sbjct: 406 GRCVNTQGSFLCQCGRGY----TGPRCETDVNECL-SGPCRNQATCLDRIGQFTCICMAG 460
Score = 79.4 bits (187), Expect = 8e-15
Identities = 65/188 (34%), Positives = 79/188 (42%), Gaps = 14/188 (7%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
V+ S CVC G R + D C +P C G Y C C GY +G
Sbjct: 1062 VDEDSSHYCVCPEG-RTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGY----NG 1116
Query: 189 ANCRD-VDECERDTHTCQQ--ICSNTEGSYECSCEDGY-----EKRGDACVDINECHEEG 344
NC D VDEC + CQ C + Y CSC G E D C
Sbjct: 1117 DNCEDDVDECA--SQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGP 1174
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQA----PC-RNYAGG 506
C G CV+L+G FRC CP GY G RC D +EC ++G C A C ++ GG
Sbjct: 1175 RCLHNGTCVDLVGGFRCTCPPGY----TGLRCEADINEC-RSGACHAAHTRDCLQDPGGG 1229
Query: 507 YRCDCPVG 530
+RC C G
Sbjct: 1230 FRCLCHAG 1237
Score = 78.6 bits (185), Expect = 1e-14
Identities = 64/180 (35%), Positives = 86/180 (47%), Gaps = 10/180 (5%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGR-DECAVRPPPCDQ--LCHNTDGSYDCLCRTGY--ELDED 185
G F C C PGY+ GR R DEC V PC C NT GS+ C C GY L E+
Sbjct: 140 GRFLCSCPPGYQ--GRSCRSDVDECRV-GEPCRHGGTCLNTPGSFRCQCPAGYTGPLCEN 196
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
A C R+ TC+Q + + +Y+C+C G+E G C V++++C C + G
Sbjct: 197 PAVPCAPSPC-RNGGTCRQ---SGDLTYDCACLPGFE--GQNCEVNVDDCPGHR-CLNGG 249
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCV-DRDEC-AQTGRCQ--APCRNYAGGYRCDCPVG 530
CV+ + ++ C CP + G C D DEC Q C C N GG+ C C G
Sbjct: 250 TCVDGVNTYNCQCPPEW----TGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNG 305
Score = 78.2 bits (184), Expect = 2e-14
Identities = 54/176 (30%), Positives = 70/176 (39%), Gaps = 6/176 (3%)
Frame = +3
Query: 21 GSFRCVCGPGYR-PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
G FRCVC PG+ P RD C +P C + + C C G + G C
Sbjct: 714 GGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQ----GRQC 769
Query: 198 RDVDECERDTHTCQQICSNTEGSYE-CSCEDGYEKRGDACV-DINECHEEGVCPSPGRCV 371
+ C + C + G CSC G++ G C D++EC C G C
Sbjct: 770 ELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQ--GPRCQQDVDECAGPAPCGPHGICT 827
Query: 372 NLLGSFRCVCPRGY---RLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
NL GSF C C GY D + C D + C G CQ + G + C C G
Sbjct: 828 NLAGSFSCTCHGGYTGPSCDQDINDC-DPNPCLNGGSCQ----DGVGSFSCSCLPG 878
Score = 75.8 bits (178), Expect = 1e-13
Identities = 54/172 (31%), Positives = 78/172 (45%), Gaps = 6/172 (3%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANC-RD 203
C C G++ R + DECA P PC +C N GS+ C C GY G +C +D
Sbjct: 796 CSCPQGWQ-GPRCQQDVDECA-GPAPCGPHGICTNLAGSFSCTCHGGYT----GPSCDQD 849
Query: 204 VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSPGRCVNLL 380
+++C+ + C + GS+ CSC G+ G C D++EC C PG C + +
Sbjct: 850 INDCDPNPCLNGGSCQDGVGSFSCSCLPGFA--GPRCARDVDECLSNP-C-GPGTCTDHV 905
Query: 381 GSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ-APCRNYAGGYRCDCPVG 530
SF C CP GY G C D +C+ + C + + C C G
Sbjct: 906 ASFTCTCPPGY----GGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPG 953
Score = 71.3 bits (167), Expect = 2e-12
Identities = 56/176 (31%), Positives = 76/176 (43%), Gaps = 6/176 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N GSF C C GY + ++C P C + GS+ C C G+ G
Sbjct: 828 NLAGSFSCTCHGGYTGPSCD-QDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFA----GP 882
Query: 192 NC-RDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSPG 362
C RDVDEC ++ C C++ S+ C+C GY G C D+ +C C + G
Sbjct: 883 RCARDVDECL--SNPCGPGTCTDHVASFTCTCPPGYG--GFHCEQDLPDCSPSS-CFNGG 937
Query: 363 RCVNLLGSFRCVCPRGY---RLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
CV+ + SF C+C GY E C+ R C G C A G+RC C
Sbjct: 938 TCVDGVNSFSCLCRPGYTGAHCQHEADPCLSR-PCLHGGVCSAA----HPGFRCTC 988
Score = 69.7 bits (163), Expect = 6e-12
Identities = 61/188 (32%), Positives = 77/188 (40%), Gaps = 14/188 (7%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
V+ + SF C+C PGY A D C RP +C + C C + G
Sbjct: 940 VDGVNSFSCLCRPGYTGA-HCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFT----G 994
Query: 189 ANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINE--CHE------- 338
C+ VD C R C T G+Y C C G+ G C DI C E
Sbjct: 995 PQCQTLVDWCSRQPCQNGGRCVQT-GAY-CLCPPGWS--GRLC-DIRSLPCREAAAQIGV 1049
Query: 339 --EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DEC-AQTGRCQAPCRNYAGG 506
E +C + G+CV+ S CVCP G G+ C D C AQ + CR Y GG
Sbjct: 1050 RLEQLCQAGGQCVDEDSSHYCVCPEG----RTGSHCEQEVDPCLAQPCQHGGTCRGYMGG 1105
Query: 507 YRCDCPVG 530
Y C+C G
Sbjct: 1106 YMCECLPG 1113
Score = 65.7 bits (153), Expect = 1e-10
Identities = 42/133 (31%), Positives = 58/133 (43%), Gaps = 6/133 (4%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNT----DGSYDCLCRTGYELDEDGANCR 200
C+C PG+ G + D C P +C ++ + C C G+ G +C
Sbjct: 65 CLCPPGW--VGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFR----GPDCS 118
Query: 201 DVDECERDTHTCQQICS-NTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVN 374
D C CS +G + CSC GY+ G +C D++EC C G C+N
Sbjct: 119 LPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQ--GRSCRSDVDECRVGEPCRHGGTCLN 176
Query: 375 LLGSFRCVCPRGY 413
GSFRC CP GY
Sbjct: 177 TPGSFRCQCPAGY 189
Score = 60.9 bits (141), Expect = 3e-09
Identities = 49/179 (27%), Positives = 72/179 (40%), Gaps = 5/179 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ + + C C G V D+CA P +C + YDC+C+ G+ G
Sbjct: 598 LDLVDKYLCRCPSGTTGVNCEVN-IDDCASNPCTFG-VCRDGINRYDCVCQPGFT----G 651
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGR 365
C +++EC C + E + C C G C+ + C S G
Sbjct: 652 PLCNVEINECASSPCGEGGSCVDGENGFRCLCPPG--SLPPLCLPPSHPCAHEPC-SHGI 708
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARC---VDRDEC-AQTGRCQAPCRNYAGGYRCDCPVG 530
C + G FRCVC G+ G RC + RD C +Q R C + G+ C CP G
Sbjct: 709 CYDAPGGFRCVCEPGW----SGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPG 763
Score = 58.4 bits (135), Expect = 2e-08
Identities = 51/175 (29%), Positives = 73/175 (41%), Gaps = 5/175 (2%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRD 203
+ C C G+ R D+C+ P PC C + S+ C C GY G C
Sbjct: 529 YECRCAEGFEGTLCD-RNVDDCS--PDPCHHGRCVDGIASFSCACAPGYT----GTRCES 581
Query: 204 -VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNL 377
VDEC C + Y C C G G C V+I++C C G C +
Sbjct: 582 QVDECRSQPCRHGGKCLDLVDKYLCRCPSG--TTGVNCEVNIDDC-ASNPCTF-GVCRDG 637
Query: 378 LGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQA-PCRNYAGGYRCDCPVGTV 536
+ + CVC G+ G C V+ +ECA + + C + G+RC CP G++
Sbjct: 638 INRYDCVCQPGFT----GPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSL 688
Score = 55.6 bits (128), Expect = 1e-07
Identities = 42/135 (31%), Positives = 54/135 (40%), Gaps = 8/135 (5%)
Frame = +3
Query: 150 CLCRTGYELDEDGANCRDVDECERDTHTCQQICSNT----EGSYECSCEDGYEKRGDACV 317
CLC G+ G C+ D C + +C ++ + C C G+ RG C
Sbjct: 65 CLCPPGWV----GERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGF--RGPDCS 118
Query: 318 DINECHEEGVCPSPGRC-VNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--AP 485
+ C C RC V G F C CP GY +G C D DEC C+
Sbjct: 119 LPDPCLSSP-CAHGARCSVGPDGRFLCSCPPGY----QGRSCRSDVDECRVGEPCRHGGT 173
Query: 486 CRNYAGGYRCDCPVG 530
C N G +RC CP G
Sbjct: 174 CLNTPGSFRCQCPAG 188
Score = 54.0 bits (124), Expect = 3e-07
Identities = 54/182 (29%), Positives = 75/182 (41%), Gaps = 12/182 (6%)
Frame = +3
Query: 27 FRCVCGPGYR-PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYE---LDEDGAN 194
FRC C + P + + D C+ +P C T G+Y CLC G+ D
Sbjct: 984 FRCTCLESFTGPQCQTLV--DWCSRQPCQNGGRCVQT-GAY-CLCPPGWSGRLCDIRSLP 1039
Query: 195 CRDVDEC--ERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSP 359
CR+ R CQ C + + S+ C C +G + G C +++ C + C
Sbjct: 1040 CREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEG--RTGSHCEQEVDPCLAQP-CQHG 1096
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ--APCRNYAGGYRCDCPVG 530
G C +G + C C GY G C D DECA CQ C + Y C CP G
Sbjct: 1097 GTCRGYMGGYMCECLPGYN----GDNCEDDVDECASQP-CQHGGSCIDLVARYLCSCPPG 1151
Query: 531 TV 536
T+
Sbjct: 1152 TL 1153
Score = 49.2 bits (112), Expect = 9e-06
Identities = 51/195 (26%), Positives = 73/195 (37%), Gaps = 21/195 (10%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPP-----PC--DQLCHNTDGSYDCLCRTG 167
++ + + C C PG + D+C PP C + C + G + C C G
Sbjct: 1138 IDLVARYLCSCPPGTLGVLCEIN-EDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPG 1196
Query: 168 YELDEDGANCR-DVDECERDT----HTCQQICSNTEGSYECSCEDGYEKRGDACVDI--- 323
Y G C D++EC HT + + G + C C G+ G C +
Sbjct: 1197 YT----GLRCEADINECRSGACHAAHT-RDCLQDPGGGFRCLCHAGFS--GPRCQTVLSP 1249
Query: 324 ---NECHEEGVC-PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQA--P 485
C G C PSPG L +F C C + + G RC + +C P
Sbjct: 1250 CESQPCQHGGQCRPSPGPGGGL--TFTCHCAQPFW----GPRCERVARSCRELQCPVGVP 1303
Query: 486 CRNYAGGYRCDCPVG 530
C+ G RC CP G
Sbjct: 1304 CQQTPRGPRCACPPG 1318
>AY720432-1|AAU14134.1| 1285|Homo sapiens crumbs-like protein 2
precursor protein.
Length = 1285
Score = 85.4 bits (202), Expect = 1e-16
Identities = 62/172 (36%), Positives = 79/172 (45%), Gaps = 7/172 (4%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-D 203
FRC C PG++ R DECA RP C N Y+C C GY G C +
Sbjct: 92 FRCYCVPGFQ-GPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYA----GVTCEME 146
Query: 204 VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNLL 380
VDEC C + GS+ C C GY G C +D++EC + C G C +L+
Sbjct: 147 VDECASAPCLHGGSCLDGVGSFRCVCAPGY--GGTRCQLDLDECQSQ-PCAHGGTCHDLV 203
Query: 381 GSFRCVCP-RGYRLDAEGARCVDRD--ECAQTGRCQ--APCRNYAGGYRCDC 521
FRC C GY EG C +R+ ECA + C+ A C G +RC C
Sbjct: 204 NGFRCDCAGTGY----EGTHC-EREVLECA-SAPCEHNASCLEGLGSFRCLC 249
Score = 81.0 bits (191), Expect = 3e-15
Identities = 70/197 (35%), Positives = 86/197 (43%), Gaps = 26/197 (13%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCR-TGYELDEDGAN 194
+GSFRCVC PGY R DEC +P CH+ + C C TGYE G +
Sbjct: 165 VGSFRCVCAPGY-GGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYE----GTH 219
Query: 195 C-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRC 368
C R+V EC C GS+ C C GY G+ C VD +EC C GRC
Sbjct: 220 CEREVLECASAPCEHNASCLEGLGSFRCLCWPGYS--GELCEVDEDEC-ASSPCQHGGRC 276
Query: 369 VN-----LLG----------SFR------CVCPRGYRLDAEGARC-VDRDECAQTGRCQ- 479
+ L G SFR C CP G+ EGA C V+ DECA
Sbjct: 277 LQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGF----EGADCGVEVDECASRPCLNG 332
Query: 480 APCRNYAGGYRCDCPVG 530
C++ G++C CP G
Sbjct: 333 GHCQDLPNGFQCHCPDG 349
Score = 78.2 bits (184), Expect = 2e-14
Identities = 54/152 (35%), Positives = 71/152 (46%), Gaps = 8/152 (5%)
Frame = +3
Query: 90 CAVRPPPCDQLC--HNTDGS-YDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNT 257
CA +P LC D + + C C G++ G C D+DEC C N
Sbjct: 71 CATQPCHHGALCVPQGPDPTGFRCYCVPGFQ----GPRCELDIDECASRPCHHGATCRNL 126
Query: 258 EGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGA 434
YEC C GY G C ++++EC C G C++ +GSFRCVC GY G
Sbjct: 127 ADRYECHCPLGYA--GVTCEMEVDEC-ASAPCLHGGSCLDGVGSFRCVCAPGY----GGT 179
Query: 435 RC-VDRDECAQTGRCQ--APCRNYAGGYRCDC 521
RC +D DEC Q+ C C + G+RCDC
Sbjct: 180 RCQLDLDEC-QSQPCAHGGTCHDLVNGFRCDC 210
Score = 66.9 bits (156), Expect = 4e-11
Identities = 45/133 (33%), Positives = 57/133 (42%), Gaps = 5/133 (3%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-D 203
F C C PG+ A GV DECA RP C + + C C GY G C D
Sbjct: 304 FLCHCPPGFEGADCGVEV-DECASRPCLNGGHCQDLPNGFQCHCPDGYA----GPTCEED 358
Query: 204 VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNL-- 377
VDEC D CS+T Y C C + + R D V + C + CP C+ +
Sbjct: 359 VDECLSDPCLHGGTCSDTVAGYICRCPETWGGR-DCSVQLTGC-QGHTCPLAATCIPIFE 416
Query: 378 --LGSFRCVCPRG 410
+ S+ C CP G
Sbjct: 417 SGVHSYVCHCPPG 429
Score = 63.3 bits (147), Expect = 5e-10
Identities = 58/190 (30%), Positives = 76/190 (40%), Gaps = 21/190 (11%)
Frame = +3
Query: 18 IGSFRCVC-GPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGY-----ELD 179
+ FRC C G GY R ECA P + C GS+ CLC GY E+D
Sbjct: 203 VNGFRCDCAGTGYEGT-HCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVD 261
Query: 180 ED---GANCRDVDEC--ERDTHTCQQICSNTEGSYE--------CSCEDGYEKRGDACVD 320
ED + C+ C D + + G++ C C G+E D V+
Sbjct: 262 EDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEG-ADCGVE 320
Query: 321 INECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ-APCRN 494
++EC C + G C +L F+C CP GY G C D DEC C +
Sbjct: 321 VDECASRP-CLNGGHCQDLPNGFQCHCPDGY----AGPTCEEDVDECLSDPCLHGGTCSD 375
Query: 495 YAGGYRCDCP 524
GY C CP
Sbjct: 376 TVAGYICRCP 385
Score = 48.4 bits (110), Expect = 2e-05
Identities = 38/99 (38%), Positives = 43/99 (43%), Gaps = 4/99 (4%)
Frame = +3
Query: 246 CSNTE-GSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLD 422
C TE G Y C E RG A CH +C G FRC C G+
Sbjct: 53 CQATESGGYTCG---PMEPRGCAT---QPCHHGALCVPQGPDPT---GFRCYCVPGF--- 100
Query: 423 AEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
+G RC +D DECA C A CRN A Y C CP+G
Sbjct: 101 -QGPRCELDIDECASRP-CHHGATCRNLADRYECHCPLG 137
Score = 45.6 bits (103), Expect = 1e-04
Identities = 42/155 (27%), Positives = 56/155 (36%), Gaps = 9/155 (5%)
Frame = +3
Query: 45 PGYRPAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCR-DVDEC 215
PG G RG CA P PC D C + ++ C C G+E G C VD C
Sbjct: 1045 PGTPAPILGCRGAPVCA--PSPCLHDGACRDLFDAFACACGPGWE----GPRCEAHVDPC 1098
Query: 216 ERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC---VDINECHEEGVCPSPGRCVNLLGS 386
+ ++ +G +EC C G+ G C V EC C C +
Sbjct: 1099 HSAPCARGRCHTHPDGRFECRCPPGF--GGPRCRLPVPSKECSLNVTCLDGSPCEGGSPA 1156
Query: 387 FRCVCPR---GYRLDAEGARCVDRDECAQTGRCQA 482
C C G R C + + C G C+A
Sbjct: 1157 ANCSCLEGLAGQRCQVPTLPC-EANPCLNGGTCRA 1190
Score = 44.4 bits (100), Expect = 3e-04
Identities = 41/134 (30%), Positives = 53/134 (39%), Gaps = 8/134 (5%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCH-NTDGSYDCLCRTGYELDEDGANC 197
+F C CGPG+ R D C PC + CH + DG ++C C G+ G C
Sbjct: 1077 AFACACGPGWE-GPRCEAHVDPC--HSAPCARGRCHTHPDGRFECRCPPGF----GGPRC 1129
Query: 198 R---DVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSP 359
R EC + TC C + CSC +G G C V C E C +
Sbjct: 1130 RLPVPSKECSLNV-TCLDGSPCEGGSPAANCSCLEGL--AGQRCQVPTLPC-EANPCLNG 1185
Query: 360 GRCVNLLGSFRCVC 401
G C G C+C
Sbjct: 1186 GTCRAAGGVSECIC 1199
Score = 30.7 bits (66), Expect = 3.6
Identities = 18/46 (39%), Positives = 20/46 (43%)
Frame = +3
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP 485
C G CV+L FRC C R +R G C D A G AP
Sbjct: 614 CVHGGSCVDLWTHFRCDCARPHR----GPTCADEIPAATFGLGGAP 655
>AL445489-4|CAI39793.1| 1285|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1285
Score = 85.4 bits (202), Expect = 1e-16
Identities = 62/172 (36%), Positives = 79/172 (45%), Gaps = 7/172 (4%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-D 203
FRC C PG++ R DECA RP C N Y+C C GY G C +
Sbjct: 92 FRCYCVPGFQ-GPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYA----GVTCEME 146
Query: 204 VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNLL 380
VDEC C + GS+ C C GY G C +D++EC + C G C +L+
Sbjct: 147 VDECASAPCLHGGSCLDGVGSFRCVCAPGY--GGTRCQLDLDECQSQ-PCAHGGTCHDLV 203
Query: 381 GSFRCVCP-RGYRLDAEGARCVDRD--ECAQTGRCQ--APCRNYAGGYRCDC 521
FRC C GY EG C +R+ ECA + C+ A C G +RC C
Sbjct: 204 NGFRCDCAGTGY----EGTHC-EREVLECA-SAPCEHNASCLEGLGSFRCLC 249
Score = 81.0 bits (191), Expect = 3e-15
Identities = 70/197 (35%), Positives = 86/197 (43%), Gaps = 26/197 (13%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCR-TGYELDEDGAN 194
+GSFRCVC PGY R DEC +P CH+ + C C TGYE G +
Sbjct: 165 VGSFRCVCAPGY-GGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYE----GTH 219
Query: 195 C-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRC 368
C R+V EC C GS+ C C GY G+ C VD +EC C GRC
Sbjct: 220 CEREVLECASAPCEHNASCLEGLGSFRCLCWPGYS--GELCEVDEDEC-ASSPCQHGGRC 276
Query: 369 VN-----LLG----------SFR------CVCPRGYRLDAEGARC-VDRDECAQTGRCQ- 479
+ L G SFR C CP G+ EGA C V+ DECA
Sbjct: 277 LQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGF----EGADCGVEVDECASRPCLNG 332
Query: 480 APCRNYAGGYRCDCPVG 530
C++ G++C CP G
Sbjct: 333 GHCQDLPNGFQCHCPDG 349
Score = 78.2 bits (184), Expect = 2e-14
Identities = 54/152 (35%), Positives = 71/152 (46%), Gaps = 8/152 (5%)
Frame = +3
Query: 90 CAVRPPPCDQLC--HNTDGS-YDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNT 257
CA +P LC D + + C C G++ G C D+DEC C N
Sbjct: 71 CATQPCHHGALCVPQGPDPTGFRCYCVPGFQ----GPRCELDIDECASRPCHHGATCRNL 126
Query: 258 EGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGA 434
YEC C GY G C ++++EC C G C++ +GSFRCVC GY G
Sbjct: 127 ADRYECHCPLGYA--GVTCEMEVDEC-ASAPCLHGGSCLDGVGSFRCVCAPGY----GGT 179
Query: 435 RC-VDRDECAQTGRCQ--APCRNYAGGYRCDC 521
RC +D DEC Q+ C C + G+RCDC
Sbjct: 180 RCQLDLDEC-QSQPCAHGGTCHDLVNGFRCDC 210
Score = 66.9 bits (156), Expect = 4e-11
Identities = 45/133 (33%), Positives = 57/133 (42%), Gaps = 5/133 (3%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-D 203
F C C PG+ A GV DECA RP C + + C C GY G C D
Sbjct: 304 FLCHCPPGFEGADCGVEV-DECASRPCLNGGHCQDLPNGFQCHCPDGYA----GPTCEED 358
Query: 204 VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNL-- 377
VDEC D CS+T Y C C + + R D V + C + CP C+ +
Sbjct: 359 VDECLSDPCLHGGTCSDTVAGYICRCPETWGGR-DCSVQLTGC-QGHTCPLAATCIPIFE 416
Query: 378 --LGSFRCVCPRG 410
+ S+ C CP G
Sbjct: 417 SGVHSYVCHCPPG 429
Score = 63.3 bits (147), Expect = 5e-10
Identities = 58/190 (30%), Positives = 76/190 (40%), Gaps = 21/190 (11%)
Frame = +3
Query: 18 IGSFRCVC-GPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGY-----ELD 179
+ FRC C G GY R ECA P + C GS+ CLC GY E+D
Sbjct: 203 VNGFRCDCAGTGYEGT-HCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVD 261
Query: 180 ED---GANCRDVDEC--ERDTHTCQQICSNTEGSYE--------CSCEDGYEKRGDACVD 320
ED + C+ C D + + G++ C C G+E D V+
Sbjct: 262 EDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEG-ADCGVE 320
Query: 321 INECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ-APCRN 494
++EC C + G C +L F+C CP GY G C D DEC C +
Sbjct: 321 VDECASRP-CLNGGHCQDLPNGFQCHCPDGY----AGPTCEEDVDECLSDPCLHGGTCSD 375
Query: 495 YAGGYRCDCP 524
GY C CP
Sbjct: 376 TVAGYICRCP 385
Score = 48.4 bits (110), Expect = 2e-05
Identities = 38/99 (38%), Positives = 43/99 (43%), Gaps = 4/99 (4%)
Frame = +3
Query: 246 CSNTE-GSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLD 422
C TE G Y C E RG A CH +C G FRC C G+
Sbjct: 53 CQATESGGYTCG---PMEPRGCAT---QPCHHGALCVPQGPDPT---GFRCYCVPGF--- 100
Query: 423 AEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
+G RC +D DECA C A CRN A Y C CP+G
Sbjct: 101 -QGPRCELDIDECASRP-CHHGATCRNLADRYECHCPLG 137
Score = 45.6 bits (103), Expect = 1e-04
Identities = 42/155 (27%), Positives = 56/155 (36%), Gaps = 9/155 (5%)
Frame = +3
Query: 45 PGYRPAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCR-DVDEC 215
PG G RG CA P PC D C + ++ C C G+E G C VD C
Sbjct: 1045 PGTPAPILGCRGAPVCA--PSPCLHDGACRDLFDAFACACGPGWE----GPRCEAHVDPC 1098
Query: 216 ERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC---VDINECHEEGVCPSPGRCVNLLGS 386
+ ++ +G +EC C G+ G C V EC C C +
Sbjct: 1099 HSAPCARGRCHTHPDGRFECRCPPGF--GGPRCRLPVPSKECSLNVTCLDGSPCEGGSPA 1156
Query: 387 FRCVCPR---GYRLDAEGARCVDRDECAQTGRCQA 482
C C G R C + + C G C+A
Sbjct: 1157 ANCSCLEGLAGQRCQVPTLPC-EANPCLNGGTCRA 1190
Score = 44.4 bits (100), Expect = 3e-04
Identities = 41/134 (30%), Positives = 53/134 (39%), Gaps = 8/134 (5%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCH-NTDGSYDCLCRTGYELDEDGANC 197
+F C CGPG+ R D C PC + CH + DG ++C C G+ G C
Sbjct: 1077 AFACACGPGWE-GPRCEAHVDPC--HSAPCARGRCHTHPDGRFECRCPPGF----GGPRC 1129
Query: 198 R---DVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSP 359
R EC + TC C + CSC +G G C V C E C +
Sbjct: 1130 RLPVPSKECSLNV-TCLDGSPCEGGSPAANCSCLEGL--AGQRCQVPTLPC-EANPCLNG 1185
Query: 360 GRCVNLLGSFRCVC 401
G C G C+C
Sbjct: 1186 GTCRAAGGVSECIC 1199
Score = 30.7 bits (66), Expect = 3.6
Identities = 18/46 (39%), Positives = 20/46 (43%)
Frame = +3
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP 485
C G CV+L FRC C R +R G C D A G AP
Sbjct: 614 CVHGGSCVDLWTHFRCDCARPHR----GPTCADEIPAATFGLGGAP 655
>AL445489-3|CAM14433.1| 1176|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1176
Score = 85.4 bits (202), Expect = 1e-16
Identities = 62/172 (36%), Positives = 79/172 (45%), Gaps = 7/172 (4%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-D 203
FRC C PG++ R DECA RP C N Y+C C GY G C +
Sbjct: 92 FRCYCVPGFQ-GPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYA----GVTCEME 146
Query: 204 VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNLL 380
VDEC C + GS+ C C GY G C +D++EC + C G C +L+
Sbjct: 147 VDECASAPCLHGGSCLDGVGSFRCVCAPGY--GGTRCQLDLDECQSQ-PCAHGGTCHDLV 203
Query: 381 GSFRCVCP-RGYRLDAEGARCVDRD--ECAQTGRCQ--APCRNYAGGYRCDC 521
FRC C GY EG C +R+ ECA + C+ A C G +RC C
Sbjct: 204 NGFRCDCAGTGY----EGTHC-EREVLECA-SAPCEHNASCLEGLGSFRCLC 249
Score = 81.0 bits (191), Expect = 3e-15
Identities = 70/197 (35%), Positives = 86/197 (43%), Gaps = 26/197 (13%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCR-TGYELDEDGAN 194
+GSFRCVC PGY R DEC +P CH+ + C C TGYE G +
Sbjct: 165 VGSFRCVCAPGY-GGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYE----GTH 219
Query: 195 C-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRC 368
C R+V EC C GS+ C C GY G+ C VD +EC C GRC
Sbjct: 220 CEREVLECASAPCEHNASCLEGLGSFRCLCWPGYS--GELCEVDEDEC-ASSPCQHGGRC 276
Query: 369 VN-----LLG----------SFR------CVCPRGYRLDAEGARC-VDRDECAQTGRCQ- 479
+ L G SFR C CP G+ EGA C V+ DECA
Sbjct: 277 LQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGF----EGADCGVEVDECASRPCLNG 332
Query: 480 APCRNYAGGYRCDCPVG 530
C++ G++C CP G
Sbjct: 333 GHCQDLPNGFQCHCPDG 349
Score = 78.2 bits (184), Expect = 2e-14
Identities = 54/152 (35%), Positives = 71/152 (46%), Gaps = 8/152 (5%)
Frame = +3
Query: 90 CAVRPPPCDQLC--HNTDGS-YDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNT 257
CA +P LC D + + C C G++ G C D+DEC C N
Sbjct: 71 CATQPCHHGALCVPQGPDPTGFRCYCVPGFQ----GPRCELDIDECASRPCHHGATCRNL 126
Query: 258 EGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGA 434
YEC C GY G C ++++EC C G C++ +GSFRCVC GY G
Sbjct: 127 ADRYECHCPLGYA--GVTCEMEVDEC-ASAPCLHGGSCLDGVGSFRCVCAPGY----GGT 179
Query: 435 RC-VDRDECAQTGRCQ--APCRNYAGGYRCDC 521
RC +D DEC Q+ C C + G+RCDC
Sbjct: 180 RCQLDLDEC-QSQPCAHGGTCHDLVNGFRCDC 210
Score = 66.9 bits (156), Expect = 4e-11
Identities = 45/133 (33%), Positives = 57/133 (42%), Gaps = 5/133 (3%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-D 203
F C C PG+ A GV DECA RP C + + C C GY G C D
Sbjct: 304 FLCHCPPGFEGADCGVEV-DECASRPCLNGGHCQDLPNGFQCHCPDGYA----GPTCEED 358
Query: 204 VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNL-- 377
VDEC D CS+T Y C C + + R D V + C + CP C+ +
Sbjct: 359 VDECLSDPCLHGGTCSDTVAGYICRCPETWGGR-DCSVQLTGC-QGHTCPLAATCIPIFE 416
Query: 378 --LGSFRCVCPRG 410
+ S+ C CP G
Sbjct: 417 SGVHSYVCHCPPG 429
Score = 63.3 bits (147), Expect = 5e-10
Identities = 58/190 (30%), Positives = 76/190 (40%), Gaps = 21/190 (11%)
Frame = +3
Query: 18 IGSFRCVC-GPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGY-----ELD 179
+ FRC C G GY R ECA P + C GS+ CLC GY E+D
Sbjct: 203 VNGFRCDCAGTGYEGT-HCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVD 261
Query: 180 ED---GANCRDVDEC--ERDTHTCQQICSNTEGSYE--------CSCEDGYEKRGDACVD 320
ED + C+ C D + + G++ C C G+E D V+
Sbjct: 262 EDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEG-ADCGVE 320
Query: 321 INECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ-APCRN 494
++EC C + G C +L F+C CP GY G C D DEC C +
Sbjct: 321 VDECASRP-CLNGGHCQDLPNGFQCHCPDGY----AGPTCEEDVDECLSDPCLHGGTCSD 375
Query: 495 YAGGYRCDCP 524
GY C CP
Sbjct: 376 TVAGYICRCP 385
Score = 48.4 bits (110), Expect = 2e-05
Identities = 38/99 (38%), Positives = 43/99 (43%), Gaps = 4/99 (4%)
Frame = +3
Query: 246 CSNTE-GSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLD 422
C TE G Y C E RG A CH +C G FRC C G+
Sbjct: 53 CQATESGGYTCG---PMEPRGCAT---QPCHHGALCVPQGPDPT---GFRCYCVPGF--- 100
Query: 423 AEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
+G RC +D DECA C A CRN A Y C CP+G
Sbjct: 101 -QGPRCELDIDECASRP-CHHGATCRNLADRYECHCPLG 137
Score = 39.1 bits (87), Expect = 0.010
Identities = 26/86 (30%), Positives = 36/86 (41%), Gaps = 3/86 (3%)
Frame = +3
Query: 45 PGYRPAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCR-DVDEC 215
PG G RG CA P PC D C + ++ C C G+E G C VD C
Sbjct: 1045 PGTPAPILGCRGAPVCA--PSPCLHDGACRDLFDAFACACGPGWE----GPRCEAHVDPC 1098
Query: 216 ERDTHTCQQICSNTEGSYECSCEDGY 293
+ ++ +G +EC C G+
Sbjct: 1099 HSAPCARGRCHTHPDGRFECRCPPGF 1124
Score = 37.1 bits (82), Expect = 0.041
Identities = 25/74 (33%), Positives = 31/74 (41%), Gaps = 7/74 (9%)
Frame = +3
Query: 330 CHEEGVC-PSP----GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQAPCR 491
C VC PSP G C +L +F C C G+ EG RC D C + C
Sbjct: 1054 CRGAPVCAPSPCLHDGACRDLFDAFACACGPGW----EGPRCEAHVDPCHSAPCARGRCH 1109
Query: 492 NYAGG-YRCDCPVG 530
+ G + C CP G
Sbjct: 1110 THPDGRFECRCPPG 1123
Score = 34.7 bits (76), Expect = 0.22
Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 2/75 (2%)
Frame = +3
Query: 195 CRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRC- 368
CR C C + ++ C+C G+E G C ++ CH C + GRC
Sbjct: 1054 CRGAPVCAPSPCLHDGACRDLFDAFACACGPGWE--GPRCEAHVDPCH-SAPC-ARGRCH 1109
Query: 369 VNLLGSFRCVCPRGY 413
+ G F C CP G+
Sbjct: 1110 THPDGRFECRCPPGF 1124
Score = 33.1 bits (72), Expect = 0.67
Identities = 21/61 (34%), Positives = 28/61 (45%), Gaps = 2/61 (3%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCH-NTDGSYDCLCRTGYELDEDGANC 197
+F C CGPG+ R D C PC + CH + DG ++C C G+ G C
Sbjct: 1077 AFACACGPGWE-GPRCEAHVDPC--HSAPCARGRCHTHPDGRFECRCPPGF----GGPRC 1129
Query: 198 R 200
R
Sbjct: 1130 R 1130
Score = 30.7 bits (66), Expect = 3.6
Identities = 18/46 (39%), Positives = 20/46 (43%)
Frame = +3
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP 485
C G CV+L FRC C R +R G C D A G AP
Sbjct: 614 CVHGGSCVDLWTHFRCDCARPHR----GPTCADEIPAATFGLGGAP 655
>AL365504-3|CAI41011.1| 1285|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1285
Score = 85.4 bits (202), Expect = 1e-16
Identities = 62/172 (36%), Positives = 79/172 (45%), Gaps = 7/172 (4%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-D 203
FRC C PG++ R DECA RP C N Y+C C GY G C +
Sbjct: 92 FRCYCVPGFQ-GPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYA----GVTCEME 146
Query: 204 VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNLL 380
VDEC C + GS+ C C GY G C +D++EC + C G C +L+
Sbjct: 147 VDECASAPCLHGGSCLDGVGSFRCVCAPGY--GGTRCQLDLDECQSQ-PCAHGGTCHDLV 203
Query: 381 GSFRCVCP-RGYRLDAEGARCVDRD--ECAQTGRCQ--APCRNYAGGYRCDC 521
FRC C GY EG C +R+ ECA + C+ A C G +RC C
Sbjct: 204 NGFRCDCAGTGY----EGTHC-EREVLECA-SAPCEHNASCLEGLGSFRCLC 249
Score = 81.0 bits (191), Expect = 3e-15
Identities = 70/197 (35%), Positives = 86/197 (43%), Gaps = 26/197 (13%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCR-TGYELDEDGAN 194
+GSFRCVC PGY R DEC +P CH+ + C C TGYE G +
Sbjct: 165 VGSFRCVCAPGY-GGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYE----GTH 219
Query: 195 C-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRC 368
C R+V EC C GS+ C C GY G+ C VD +EC C GRC
Sbjct: 220 CEREVLECASAPCEHNASCLEGLGSFRCLCWPGYS--GELCEVDEDEC-ASSPCQHGGRC 276
Query: 369 VN-----LLG----------SFR------CVCPRGYRLDAEGARC-VDRDECAQTGRCQ- 479
+ L G SFR C CP G+ EGA C V+ DECA
Sbjct: 277 LQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGF----EGADCGVEVDECASRPCLNG 332
Query: 480 APCRNYAGGYRCDCPVG 530
C++ G++C CP G
Sbjct: 333 GHCQDLPNGFQCHCPDG 349
Score = 78.2 bits (184), Expect = 2e-14
Identities = 54/152 (35%), Positives = 71/152 (46%), Gaps = 8/152 (5%)
Frame = +3
Query: 90 CAVRPPPCDQLC--HNTDGS-YDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNT 257
CA +P LC D + + C C G++ G C D+DEC C N
Sbjct: 71 CATQPCHHGALCVPQGPDPTGFRCYCVPGFQ----GPRCELDIDECASRPCHHGATCRNL 126
Query: 258 EGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGA 434
YEC C GY G C ++++EC C G C++ +GSFRCVC GY G
Sbjct: 127 ADRYECHCPLGYA--GVTCEMEVDEC-ASAPCLHGGSCLDGVGSFRCVCAPGY----GGT 179
Query: 435 RC-VDRDECAQTGRCQ--APCRNYAGGYRCDC 521
RC +D DEC Q+ C C + G+RCDC
Sbjct: 180 RCQLDLDEC-QSQPCAHGGTCHDLVNGFRCDC 210
Score = 66.9 bits (156), Expect = 4e-11
Identities = 45/133 (33%), Positives = 57/133 (42%), Gaps = 5/133 (3%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-D 203
F C C PG+ A GV DECA RP C + + C C GY G C D
Sbjct: 304 FLCHCPPGFEGADCGVEV-DECASRPCLNGGHCQDLPNGFQCHCPDGYA----GPTCEED 358
Query: 204 VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNL-- 377
VDEC D CS+T Y C C + + R D V + C + CP C+ +
Sbjct: 359 VDECLSDPCLHGGTCSDTVAGYICRCPETWGGR-DCSVQLTGC-QGHTCPLAATCIPIFE 416
Query: 378 --LGSFRCVCPRG 410
+ S+ C CP G
Sbjct: 417 SGVHSYVCHCPPG 429
Score = 63.3 bits (147), Expect = 5e-10
Identities = 58/190 (30%), Positives = 76/190 (40%), Gaps = 21/190 (11%)
Frame = +3
Query: 18 IGSFRCVC-GPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGY-----ELD 179
+ FRC C G GY R ECA P + C GS+ CLC GY E+D
Sbjct: 203 VNGFRCDCAGTGYEGT-HCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVD 261
Query: 180 ED---GANCRDVDEC--ERDTHTCQQICSNTEGSYE--------CSCEDGYEKRGDACVD 320
ED + C+ C D + + G++ C C G+E D V+
Sbjct: 262 EDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEG-ADCGVE 320
Query: 321 INECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ-APCRN 494
++EC C + G C +L F+C CP GY G C D DEC C +
Sbjct: 321 VDECASRP-CLNGGHCQDLPNGFQCHCPDGY----AGPTCEEDVDECLSDPCLHGGTCSD 375
Query: 495 YAGGYRCDCP 524
GY C CP
Sbjct: 376 TVAGYICRCP 385
Score = 48.4 bits (110), Expect = 2e-05
Identities = 38/99 (38%), Positives = 43/99 (43%), Gaps = 4/99 (4%)
Frame = +3
Query: 246 CSNTE-GSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLD 422
C TE G Y C E RG A CH +C G FRC C G+
Sbjct: 53 CQATESGGYTCG---PMEPRGCAT---QPCHHGALCVPQGPDPT---GFRCYCVPGF--- 100
Query: 423 AEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
+G RC +D DECA C A CRN A Y C CP+G
Sbjct: 101 -QGPRCELDIDECASRP-CHHGATCRNLADRYECHCPLG 137
Score = 45.6 bits (103), Expect = 1e-04
Identities = 42/155 (27%), Positives = 56/155 (36%), Gaps = 9/155 (5%)
Frame = +3
Query: 45 PGYRPAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCR-DVDEC 215
PG G RG CA P PC D C + ++ C C G+E G C VD C
Sbjct: 1045 PGTPAPILGCRGAPVCA--PSPCLHDGACRDLFDAFACACGPGWE----GPRCEAHVDPC 1098
Query: 216 ERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC---VDINECHEEGVCPSPGRCVNLLGS 386
+ ++ +G +EC C G+ G C V EC C C +
Sbjct: 1099 HSAPCARGRCHTHPDGRFECRCPPGF--GGPRCRLPVPSKECSLNVTCLDGSPCEGGSPA 1156
Query: 387 FRCVCPR---GYRLDAEGARCVDRDECAQTGRCQA 482
C C G R C + + C G C+A
Sbjct: 1157 ANCSCLEGLAGQRCQVPTLPC-EANPCLNGGTCRA 1190
Score = 44.4 bits (100), Expect = 3e-04
Identities = 41/134 (30%), Positives = 53/134 (39%), Gaps = 8/134 (5%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCH-NTDGSYDCLCRTGYELDEDGANC 197
+F C CGPG+ R D C PC + CH + DG ++C C G+ G C
Sbjct: 1077 AFACACGPGWE-GPRCEAHVDPC--HSAPCARGRCHTHPDGRFECRCPPGF----GGPRC 1129
Query: 198 R---DVDECERDTHTC--QQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSP 359
R EC + TC C + CSC +G G C V C E C +
Sbjct: 1130 RLPVPSKECSLNV-TCLDGSPCEGGSPAANCSCLEGL--AGQRCQVPTLPC-EANPCLNG 1185
Query: 360 GRCVNLLGSFRCVC 401
G C G C+C
Sbjct: 1186 GTCRAAGGVSECIC 1199
Score = 30.7 bits (66), Expect = 3.6
Identities = 18/46 (39%), Positives = 20/46 (43%)
Frame = +3
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP 485
C G CV+L FRC C R +R G C D A G AP
Sbjct: 614 CVHGGSCVDLWTHFRCDCARPHR----GPTCADEIPAATFGLGGAP 655
>AL365504-2|CAM21391.1| 1176|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1176
Score = 85.4 bits (202), Expect = 1e-16
Identities = 62/172 (36%), Positives = 79/172 (45%), Gaps = 7/172 (4%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-D 203
FRC C PG++ R DECA RP C N Y+C C GY G C +
Sbjct: 92 FRCYCVPGFQ-GPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYA----GVTCEME 146
Query: 204 VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNLL 380
VDEC C + GS+ C C GY G C +D++EC + C G C +L+
Sbjct: 147 VDECASAPCLHGGSCLDGVGSFRCVCAPGY--GGTRCQLDLDECQSQ-PCAHGGTCHDLV 203
Query: 381 GSFRCVCP-RGYRLDAEGARCVDRD--ECAQTGRCQ--APCRNYAGGYRCDC 521
FRC C GY EG C +R+ ECA + C+ A C G +RC C
Sbjct: 204 NGFRCDCAGTGY----EGTHC-EREVLECA-SAPCEHNASCLEGLGSFRCLC 249
Score = 81.0 bits (191), Expect = 3e-15
Identities = 70/197 (35%), Positives = 86/197 (43%), Gaps = 26/197 (13%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCR-TGYELDEDGAN 194
+GSFRCVC PGY R DEC +P CH+ + C C TGYE G +
Sbjct: 165 VGSFRCVCAPGY-GGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYE----GTH 219
Query: 195 C-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRC 368
C R+V EC C GS+ C C GY G+ C VD +EC C GRC
Sbjct: 220 CEREVLECASAPCEHNASCLEGLGSFRCLCWPGYS--GELCEVDEDEC-ASSPCQHGGRC 276
Query: 369 VN-----LLG----------SFR------CVCPRGYRLDAEGARC-VDRDECAQTGRCQ- 479
+ L G SFR C CP G+ EGA C V+ DECA
Sbjct: 277 LQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGF----EGADCGVEVDECASRPCLNG 332
Query: 480 APCRNYAGGYRCDCPVG 530
C++ G++C CP G
Sbjct: 333 GHCQDLPNGFQCHCPDG 349
Score = 78.2 bits (184), Expect = 2e-14
Identities = 54/152 (35%), Positives = 71/152 (46%), Gaps = 8/152 (5%)
Frame = +3
Query: 90 CAVRPPPCDQLC--HNTDGS-YDCLCRTGYELDEDGANCR-DVDECERDTHTCQQICSNT 257
CA +P LC D + + C C G++ G C D+DEC C N
Sbjct: 71 CATQPCHHGALCVPQGPDPTGFRCYCVPGFQ----GPRCELDIDECASRPCHHGATCRNL 126
Query: 258 EGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGA 434
YEC C GY G C ++++EC C G C++ +GSFRCVC GY G
Sbjct: 127 ADRYECHCPLGYA--GVTCEMEVDEC-ASAPCLHGGSCLDGVGSFRCVCAPGY----GGT 179
Query: 435 RC-VDRDECAQTGRCQ--APCRNYAGGYRCDC 521
RC +D DEC Q+ C C + G+RCDC
Sbjct: 180 RCQLDLDEC-QSQPCAHGGTCHDLVNGFRCDC 210
Score = 66.9 bits (156), Expect = 4e-11
Identities = 45/133 (33%), Positives = 57/133 (42%), Gaps = 5/133 (3%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-D 203
F C C PG+ A GV DECA RP C + + C C GY G C D
Sbjct: 304 FLCHCPPGFEGADCGVEV-DECASRPCLNGGHCQDLPNGFQCHCPDGYA----GPTCEED 358
Query: 204 VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNL-- 377
VDEC D CS+T Y C C + + R D V + C + CP C+ +
Sbjct: 359 VDECLSDPCLHGGTCSDTVAGYICRCPETWGGR-DCSVQLTGC-QGHTCPLAATCIPIFE 416
Query: 378 --LGSFRCVCPRG 410
+ S+ C CP G
Sbjct: 417 SGVHSYVCHCPPG 429
Score = 63.3 bits (147), Expect = 5e-10
Identities = 58/190 (30%), Positives = 76/190 (40%), Gaps = 21/190 (11%)
Frame = +3
Query: 18 IGSFRCVC-GPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGY-----ELD 179
+ FRC C G GY R ECA P + C GS+ CLC GY E+D
Sbjct: 203 VNGFRCDCAGTGYEGT-HCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVD 261
Query: 180 ED---GANCRDVDEC--ERDTHTCQQICSNTEGSYE--------CSCEDGYEKRGDACVD 320
ED + C+ C D + + G++ C C G+E D V+
Sbjct: 262 EDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEG-ADCGVE 320
Query: 321 INECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ-APCRN 494
++EC C + G C +L F+C CP GY G C D DEC C +
Sbjct: 321 VDECASRP-CLNGGHCQDLPNGFQCHCPDGY----AGPTCEEDVDECLSDPCLHGGTCSD 375
Query: 495 YAGGYRCDCP 524
GY C CP
Sbjct: 376 TVAGYICRCP 385
Score = 48.4 bits (110), Expect = 2e-05
Identities = 38/99 (38%), Positives = 43/99 (43%), Gaps = 4/99 (4%)
Frame = +3
Query: 246 CSNTE-GSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLD 422
C TE G Y C E RG A CH +C G FRC C G+
Sbjct: 53 CQATESGGYTCG---PMEPRGCAT---QPCHHGALCVPQGPDPT---GFRCYCVPGF--- 100
Query: 423 AEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
+G RC +D DECA C A CRN A Y C CP+G
Sbjct: 101 -QGPRCELDIDECASRP-CHHGATCRNLADRYECHCPLG 137
Score = 39.1 bits (87), Expect = 0.010
Identities = 26/86 (30%), Positives = 36/86 (41%), Gaps = 3/86 (3%)
Frame = +3
Query: 45 PGYRPAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANCR-DVDEC 215
PG G RG CA P PC D C + ++ C C G+E G C VD C
Sbjct: 1045 PGTPAPILGCRGAPVCA--PSPCLHDGACRDLFDAFACACGPGWE----GPRCEAHVDPC 1098
Query: 216 ERDTHTCQQICSNTEGSYECSCEDGY 293
+ ++ +G +EC C G+
Sbjct: 1099 HSAPCARGRCHTHPDGRFECRCPPGF 1124
Score = 37.1 bits (82), Expect = 0.041
Identities = 25/74 (33%), Positives = 31/74 (41%), Gaps = 7/74 (9%)
Frame = +3
Query: 330 CHEEGVC-PSP----GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQAPCR 491
C VC PSP G C +L +F C C G+ EG RC D C + C
Sbjct: 1054 CRGAPVCAPSPCLHDGACRDLFDAFACACGPGW----EGPRCEAHVDPCHSAPCARGRCH 1109
Query: 492 NYAGG-YRCDCPVG 530
+ G + C CP G
Sbjct: 1110 THPDGRFECRCPPG 1123
Score = 34.7 bits (76), Expect = 0.22
Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 2/75 (2%)
Frame = +3
Query: 195 CRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRC- 368
CR C C + ++ C+C G+E G C ++ CH C + GRC
Sbjct: 1054 CRGAPVCAPSPCLHDGACRDLFDAFACACGPGWE--GPRCEAHVDPCH-SAPC-ARGRCH 1109
Query: 369 VNLLGSFRCVCPRGY 413
+ G F C CP G+
Sbjct: 1110 THPDGRFECRCPPGF 1124
Score = 33.1 bits (72), Expect = 0.67
Identities = 21/61 (34%), Positives = 28/61 (45%), Gaps = 2/61 (3%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCH-NTDGSYDCLCRTGYELDEDGANC 197
+F C CGPG+ R D C PC + CH + DG ++C C G+ G C
Sbjct: 1077 AFACACGPGWE-GPRCEAHVDPC--HSAPCARGRCHTHPDGRFECRCPPGF----GGPRC 1129
Query: 198 R 200
R
Sbjct: 1130 R 1130
Score = 30.7 bits (66), Expect = 3.6
Identities = 18/46 (39%), Positives = 20/46 (43%)
Frame = +3
Query: 348 CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAP 485
C G CV+L FRC C R +R G C D A G AP
Sbjct: 614 CVHGGSCVDLWTHFRCDCARPHR----GPTCADEIPAATFGLGGAP 655
>AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein.
Length = 2321
Score = 85.4 bits (202), Expect = 1e-16
Identities = 58/179 (32%), Positives = 82/179 (45%), Gaps = 4/179 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ IG F C+C G+ V DEC P +C + + C C +G+ G
Sbjct: 447 LDRIGQFTCICMAGFTGTYCEV-DIDECQSSPCVNGGVCKDRVNGFSCTCPSGFS----G 501
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSPG 362
+ C+ DVDEC C + YEC C +G+E G C ++++C + C G
Sbjct: 502 STCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFE--GTLCDRNVDDCSPDP-CHH-G 557
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDR-DEC-AQTGRCQAPCRNYAGGYRCDCPVGT 533
RCV+ + SF C C GY G RC + DEC +Q R C + Y C CP GT
Sbjct: 558 RCVDGIASFSCACAPGY----TGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGT 612
Score = 83.4 bits (197), Expect = 5e-16
Identities = 64/185 (34%), Positives = 81/185 (43%), Gaps = 11/185 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNT-DGSYDCLCRTGYELD 179
+NT GSFRC C GY CA P PC C + D +YDC C G+E
Sbjct: 175 LNTPGSFRCQCPAGYT-GPLCENPAVPCA--PSPCRNGGTCRQSGDLTYDCACLPGFE-- 229
Query: 180 EDGANCR-DVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACV-DINECH-EEG 344
G NC +VD+C H C C + +Y C C E G C D++EC +
Sbjct: 230 --GQNCEVNVDDCPG--HRCLNGGTCVDGVNTYNCQCPP--EWTGQFCTEDVDECQLQPN 283
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRC--QAPCRNYAGGYRC 515
C + G C N LG CVC G+ G C D+CA T C A C + + C
Sbjct: 284 ACHNGGTCFNTLGGHSCVCVNGW----TGESCSQNIDDCA-TAVCFHGATCHDRVASFYC 338
Query: 516 DCPVG 530
CP+G
Sbjct: 339 ACPMG 343
Score = 81.4 bits (192), Expect = 2e-15
Identities = 58/179 (32%), Positives = 78/179 (43%), Gaps = 3/179 (1%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
R V+ I SF C C PGY R DEC +P C + Y C C +G
Sbjct: 558 RCVDGIASFSCACAPGYTGT-RCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSG----T 612
Query: 183 DGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPS 356
G NC ++D+C + T +C + Y+C C+ G+ G C V+INEC C
Sbjct: 613 TGVNCEVNIDDCASNPCTFG-VCRDGINRYDCVCQPGFT--GPLCNVEINEC-ASSPCGE 668
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE-CAQTGRCQAPCRNYAGGYRCDCPVG 530
G CV+ FRC+CP G + C+ CA C + GG+RC C G
Sbjct: 669 GGSCVDGENGFRCLCPPG----SLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPG 723
Score = 81.0 bits (191), Expect = 3e-15
Identities = 53/180 (29%), Positives = 77/180 (42%), Gaps = 4/180 (2%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
R VNT GSF C CG GY R +EC P C + G + C+C G+
Sbjct: 407 RCVNTQGSFLCQCGRGY-TGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGF---- 461
Query: 183 DGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPS 356
G C D+DEC+ +C + + C+C G+ G C +D++EC C +
Sbjct: 462 TGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFS--GSTCQLDVDEC-ASTPCRN 518
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDR--DECAQTGRCQAPCRNYAGGYRCDCPVG 530
+CV+ + C C G+ EG C DR D+C+ C + + C C G
Sbjct: 519 GAKCVDQPDGYECRCAEGF----EGTLC-DRNVDDCSPDPCHHGRCVDGIASFSCACAPG 573
Score = 80.2 bits (189), Expect = 4e-15
Identities = 61/180 (33%), Positives = 77/180 (42%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
NT+G CVC G+ + D+CA CH+ S+ C C G + G
Sbjct: 293 NTLGGHSCVCVNGWTGESCS-QNIDDCATAVCFHGATCHDRVASFYCACPMG----KTGL 347
Query: 192 NCRDVDECERDTHTCQQICSNT--EGSYECSCEDGYEKRGDAC-VDINECH-EEGVCPSP 359
C D C + IC G C+C G+ G AC D++EC C
Sbjct: 348 LCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFT--GGACDQDVDECSIGANPCEHL 405
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRC--QAPCRNYAGGYRCDCPVG 530
GRCVN GSF C C RGY G RC D +EC +G C QA C + G + C C G
Sbjct: 406 GRCVNTQGSFLCQCGRGY----TGPRCETDVNECL-SGPCRNQATCLDRIGQFTCICMAG 460
Score = 79.4 bits (187), Expect = 8e-15
Identities = 65/188 (34%), Positives = 79/188 (42%), Gaps = 14/188 (7%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
V+ S CVC G R + D C +P C G Y C C GY +G
Sbjct: 1062 VDEDSSHYCVCPEG-RTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGY----NG 1116
Query: 189 ANCRD-VDECERDTHTCQQ--ICSNTEGSYECSCEDGY-----EKRGDACVDINECHEEG 344
NC D VDEC + CQ C + Y CSC G E D C
Sbjct: 1117 DNCEDDVDECA--SQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGP 1174
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQA----PC-RNYAGG 506
C G CV+L+G FRC CP GY G RC D +EC ++G C A C ++ GG
Sbjct: 1175 RCLHNGTCVDLVGGFRCTCPPGY----TGLRCEADINEC-RSGACHAAHTRDCLQDPGGG 1229
Query: 507 YRCDCPVG 530
+RC C G
Sbjct: 1230 FRCLCHAG 1237
Score = 78.6 bits (185), Expect = 1e-14
Identities = 64/180 (35%), Positives = 86/180 (47%), Gaps = 10/180 (5%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGR-DECAVRPPPCDQ--LCHNTDGSYDCLCRTGY--ELDED 185
G F C C PGY+ GR R DEC V PC C NT GS+ C C GY L E+
Sbjct: 140 GRFLCSCPPGYQ--GRSCRSDVDECRV-GEPCRHGGTCLNTPGSFRCQCPAGYTGPLCEN 196
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
A C R+ TC+Q + + +Y+C+C G+E G C V++++C C + G
Sbjct: 197 PAVPCAPSPC-RNGGTCRQ---SGDLTYDCACLPGFE--GQNCEVNVDDCPGHR-CLNGG 249
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCV-DRDEC-AQTGRCQ--APCRNYAGGYRCDCPVG 530
CV+ + ++ C CP + G C D DEC Q C C N GG+ C C G
Sbjct: 250 TCVDGVNTYNCQCPPEW----TGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNG 305
Score = 78.2 bits (184), Expect = 2e-14
Identities = 54/176 (30%), Positives = 70/176 (39%), Gaps = 6/176 (3%)
Frame = +3
Query: 21 GSFRCVCGPGYR-PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
G FRCVC PG+ P RD C +P C + + C C G + G C
Sbjct: 714 GGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQ----GRQC 769
Query: 198 RDVDECERDTHTCQQICSNTEGSYE-CSCEDGYEKRGDACV-DINECHEEGVCPSPGRCV 371
+ C + C + G CSC G++ G C D++EC C G C
Sbjct: 770 ELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQ--GPRCQQDVDECAGPAPCGPHGICT 827
Query: 372 NLLGSFRCVCPRGY---RLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
NL GSF C C GY D + C D + C G CQ + G + C C G
Sbjct: 828 NLAGSFSCTCHGGYTGPSCDQDINDC-DPNPCLNGGSCQ----DGVGSFSCSCLPG 878
Score = 75.8 bits (178), Expect = 1e-13
Identities = 54/172 (31%), Positives = 78/172 (45%), Gaps = 6/172 (3%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANC-RD 203
C C G++ R + DECA P PC +C N GS+ C C GY G +C +D
Sbjct: 796 CSCPQGWQ-GPRCQQDVDECA-GPAPCGPHGICTNLAGSFSCTCHGGYT----GPSCDQD 849
Query: 204 VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSPGRCVNLL 380
+++C+ + C + GS+ CSC G+ G C D++EC C PG C + +
Sbjct: 850 INDCDPNPCLNGGSCQDGVGSFSCSCLPGFA--GPRCARDVDECLSNP-C-GPGTCTDHV 905
Query: 381 GSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ-APCRNYAGGYRCDCPVG 530
SF C CP GY G C D +C+ + C + + C C G
Sbjct: 906 ASFTCTCPPGY----GGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPG 953
Score = 71.3 bits (167), Expect = 2e-12
Identities = 56/176 (31%), Positives = 76/176 (43%), Gaps = 6/176 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N GSF C C GY + ++C P C + GS+ C C G+ G
Sbjct: 828 NLAGSFSCTCHGGYTGPSCD-QDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFA----GP 882
Query: 192 NC-RDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSPG 362
C RDVDEC ++ C C++ S+ C+C GY G C D+ +C C + G
Sbjct: 883 RCARDVDECL--SNPCGPGTCTDHVASFTCTCPPGYG--GFHCEQDLPDCSPSS-CFNGG 937
Query: 363 RCVNLLGSFRCVCPRGY---RLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
CV+ + SF C+C GY E C+ R C G C A G+RC C
Sbjct: 938 TCVDGVNSFSCLCRPGYTGAHCQHEADPCLSR-PCLHGGVCSAA----HPGFRCTC 988
Score = 69.7 bits (163), Expect = 6e-12
Identities = 61/188 (32%), Positives = 77/188 (40%), Gaps = 14/188 (7%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
V+ + SF C+C PGY A D C RP +C + C C + G
Sbjct: 940 VDGVNSFSCLCRPGYTGA-HCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFT----G 994
Query: 189 ANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINE--CHE------- 338
C+ VD C R C T G+Y C C G+ G C DI C E
Sbjct: 995 PQCQTLVDWCSRQPCQNGGRCVQT-GAY-CLCPPGWS--GRLC-DIRSLPCREAAAQIGV 1049
Query: 339 --EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DEC-AQTGRCQAPCRNYAGG 506
E +C + G+CV+ S CVCP G G+ C D C AQ + CR Y GG
Sbjct: 1050 RLEQLCQAGGQCVDEDSSHYCVCPEG----RTGSHCEQEVDPCLAQPCQHGGTCRGYMGG 1105
Query: 507 YRCDCPVG 530
Y C+C G
Sbjct: 1106 YMCECLPG 1113
Score = 65.7 bits (153), Expect = 1e-10
Identities = 42/133 (31%), Positives = 58/133 (43%), Gaps = 6/133 (4%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNT----DGSYDCLCRTGYELDEDGANCR 200
C+C PG+ G + D C P +C ++ + C C G+ G +C
Sbjct: 65 CLCPPGW--VGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFR----GPDCS 118
Query: 201 DVDECERDTHTCQQICS-NTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVN 374
D C CS +G + CSC GY+ G +C D++EC C G C+N
Sbjct: 119 LPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQ--GRSCRSDVDECRVGEPCRHGGTCLN 176
Query: 375 LLGSFRCVCPRGY 413
GSFRC CP GY
Sbjct: 177 TPGSFRCQCPAGY 189
Score = 60.9 bits (141), Expect = 3e-09
Identities = 49/179 (27%), Positives = 72/179 (40%), Gaps = 5/179 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ + + C C G V D+CA P +C + YDC+C+ G+ G
Sbjct: 598 LDLVDKYLCRCPSGTTGVNCEVN-IDDCASNPCTFG-VCRDGINRYDCVCQPGFT----G 651
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGR 365
C +++EC C + E + C C G C+ + C S G
Sbjct: 652 PLCNVEINECASSPCGEGGSCVDGENGFRCLCPPG--SLPPLCLPPSHPCAHEPC-SHGI 708
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARC---VDRDEC-AQTGRCQAPCRNYAGGYRCDCPVG 530
C + G FRCVC G+ G RC + RD C +Q R C + G+ C CP G
Sbjct: 709 CYDAPGGFRCVCEPGW----SGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPG 763
Score = 58.4 bits (135), Expect = 2e-08
Identities = 51/175 (29%), Positives = 73/175 (41%), Gaps = 5/175 (2%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRD 203
+ C C G+ R D+C+ P PC C + S+ C C GY G C
Sbjct: 529 YECRCAEGFEGTLCD-RNVDDCS--PDPCHHGRCVDGIASFSCACAPGYT----GTRCES 581
Query: 204 -VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNL 377
VDEC C + Y C C G G C V+I++C C G C +
Sbjct: 582 QVDECRSQPCRHGGKCLDLVDKYLCRCPSG--TTGVNCEVNIDDC-ASNPCTF-GVCRDG 637
Query: 378 LGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQA-PCRNYAGGYRCDCPVGTV 536
+ + CVC G+ G C V+ +ECA + + C + G+RC CP G++
Sbjct: 638 INRYDCVCQPGFT----GPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSL 688
Score = 55.6 bits (128), Expect = 1e-07
Identities = 42/135 (31%), Positives = 54/135 (40%), Gaps = 8/135 (5%)
Frame = +3
Query: 150 CLCRTGYELDEDGANCRDVDECERDTHTCQQICSNT----EGSYECSCEDGYEKRGDACV 317
CLC G+ G C+ D C + +C ++ + C C G+ RG C
Sbjct: 65 CLCPPGWV----GERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGF--RGPDCS 118
Query: 318 DINECHEEGVCPSPGRC-VNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--AP 485
+ C C RC V G F C CP GY +G C D DEC C+
Sbjct: 119 LPDPCLSSP-CAHGARCSVGPDGRFLCSCPPGY----QGRSCRSDVDECRVGEPCRHGGT 173
Query: 486 CRNYAGGYRCDCPVG 530
C N G +RC CP G
Sbjct: 174 CLNTPGSFRCQCPAG 188
Score = 54.0 bits (124), Expect = 3e-07
Identities = 54/182 (29%), Positives = 75/182 (41%), Gaps = 12/182 (6%)
Frame = +3
Query: 27 FRCVCGPGYR-PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYE---LDEDGAN 194
FRC C + P + + D C+ +P C T G+Y CLC G+ D
Sbjct: 984 FRCTCLESFTGPQCQTLV--DWCSRQPCQNGGRCVQT-GAY-CLCPPGWSGRLCDIRSLP 1039
Query: 195 CRDVDEC--ERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSP 359
CR+ R CQ C + + S+ C C +G + G C +++ C + C
Sbjct: 1040 CREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEG--RTGSHCEQEVDPCLAQP-CQHG 1096
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ--APCRNYAGGYRCDCPVG 530
G C +G + C C GY G C D DECA CQ C + Y C CP G
Sbjct: 1097 GTCRGYMGGYMCECLPGYN----GDNCEDDVDECASQP-CQHGGSCIDLVARYLCSCPPG 1151
Query: 531 TV 536
T+
Sbjct: 1152 TL 1153
Score = 49.2 bits (112), Expect = 9e-06
Identities = 51/195 (26%), Positives = 73/195 (37%), Gaps = 21/195 (10%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPP-----PC--DQLCHNTDGSYDCLCRTG 167
++ + + C C PG + D+C PP C + C + G + C C G
Sbjct: 1138 IDLVARYLCSCPPGTLGVLCEIN-EDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPG 1196
Query: 168 YELDEDGANCR-DVDECERDT----HTCQQICSNTEGSYECSCEDGYEKRGDACVDI--- 323
Y G C D++EC HT + + G + C C G+ G C +
Sbjct: 1197 YT----GLRCEADINECRSGACHAAHT-RDCLQDPGGGFRCLCHAGFS--GPRCQTVLSP 1249
Query: 324 ---NECHEEGVC-PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQA--P 485
C G C PSPG L +F C C + + G RC + +C P
Sbjct: 1250 CESQPCQHGGQCRPSPGPGGGL--TFTCHCAQPFW----GPRCERVARSCRELQCPVGVP 1303
Query: 486 CRNYAGGYRCDCPVG 530
C+ G RC CP G
Sbjct: 1304 CQQTPRGPRCACPPG 1318
>AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein.
Length = 2281
Score = 85.4 bits (202), Expect = 1e-16
Identities = 58/179 (32%), Positives = 82/179 (45%), Gaps = 4/179 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ IG F C+C G+ V DEC P +C + + C C +G+ G
Sbjct: 407 LDRIGQFTCICMAGFTGTYCEV-DIDECQSSPCVNGGVCKDRVNGFSCTCPSGFS----G 461
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSPG 362
+ C+ DVDEC C + YEC C +G+E G C ++++C + C G
Sbjct: 462 STCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFE--GTLCDRNVDDCSPDP-CHH-G 517
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDR-DEC-AQTGRCQAPCRNYAGGYRCDCPVGT 533
RCV+ + SF C C GY G RC + DEC +Q R C + Y C CP GT
Sbjct: 518 RCVDGIASFSCACAPGY----TGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGT 572
Score = 83.4 bits (197), Expect = 5e-16
Identities = 64/185 (34%), Positives = 81/185 (43%), Gaps = 11/185 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNT-DGSYDCLCRTGYELD 179
+NT GSFRC C GY CA P PC C + D +YDC C G+E
Sbjct: 135 LNTPGSFRCQCPAGYT-GPLCENPAVPCA--PSPCRNGGTCRQSGDLTYDCACLPGFE-- 189
Query: 180 EDGANCR-DVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACV-DINECH-EEG 344
G NC +VD+C H C C + +Y C C E G C D++EC +
Sbjct: 190 --GQNCEVNVDDCPG--HRCLNGGTCVDGVNTYNCQCPP--EWTGQFCTEDVDECQLQPN 243
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRC--QAPCRNYAGGYRC 515
C + G C N LG CVC G+ G C D+CA T C A C + + C
Sbjct: 244 ACHNGGTCFNTLGGHSCVCVNGW----TGESCSQNIDDCA-TAVCFHGATCHDRVASFYC 298
Query: 516 DCPVG 530
CP+G
Sbjct: 299 ACPMG 303
Score = 81.4 bits (192), Expect = 2e-15
Identities = 58/179 (32%), Positives = 78/179 (43%), Gaps = 3/179 (1%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
R V+ I SF C C PGY R DEC +P C + Y C C +G
Sbjct: 518 RCVDGIASFSCACAPGYTGT-RCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSG----T 572
Query: 183 DGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPS 356
G NC ++D+C + T +C + Y+C C+ G+ G C V+INEC C
Sbjct: 573 TGVNCEVNIDDCASNPCTFG-VCRDGINRYDCVCQPGFT--GPLCNVEINEC-ASSPCGE 628
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE-CAQTGRCQAPCRNYAGGYRCDCPVG 530
G CV+ FRC+CP G + C+ CA C + GG+RC C G
Sbjct: 629 GGSCVDGENGFRCLCPPG----SLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPG 683
Score = 81.0 bits (191), Expect = 3e-15
Identities = 53/180 (29%), Positives = 77/180 (42%), Gaps = 4/180 (2%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
R VNT GSF C CG GY R +EC P C + G + C+C G+
Sbjct: 367 RCVNTQGSFLCQCGRGY-TGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGF---- 421
Query: 183 DGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPS 356
G C D+DEC+ +C + + C+C G+ G C +D++EC C +
Sbjct: 422 TGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFS--GSTCQLDVDEC-ASTPCRN 478
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDR--DECAQTGRCQAPCRNYAGGYRCDCPVG 530
+CV+ + C C G+ EG C DR D+C+ C + + C C G
Sbjct: 479 GAKCVDQPDGYECRCAEGF----EGTLC-DRNVDDCSPDPCHHGRCVDGIASFSCACAPG 533
Score = 80.2 bits (189), Expect = 4e-15
Identities = 61/180 (33%), Positives = 77/180 (42%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
NT+G CVC G+ + D+CA CH+ S+ C C G + G
Sbjct: 253 NTLGGHSCVCVNGWTGESCS-QNIDDCATAVCFHGATCHDRVASFYCACPMG----KTGL 307
Query: 192 NCRDVDECERDTHTCQQICSNT--EGSYECSCEDGYEKRGDAC-VDINECH-EEGVCPSP 359
C D C + IC G C+C G+ G AC D++EC C
Sbjct: 308 LCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFT--GGACDQDVDECSIGANPCEHL 365
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRC--QAPCRNYAGGYRCDCPVG 530
GRCVN GSF C C RGY G RC D +EC +G C QA C + G + C C G
Sbjct: 366 GRCVNTQGSFLCQCGRGY----TGPRCETDVNECL-SGPCRNQATCLDRIGQFTCICMAG 420
Score = 79.4 bits (187), Expect = 8e-15
Identities = 65/188 (34%), Positives = 79/188 (42%), Gaps = 14/188 (7%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
V+ S CVC G R + D C +P C G Y C C GY +G
Sbjct: 1022 VDEDSSHYCVCPEG-RTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGY----NG 1076
Query: 189 ANCRD-VDECERDTHTCQQ--ICSNTEGSYECSCEDGY-----EKRGDACVDINECHEEG 344
NC D VDEC + CQ C + Y CSC G E D C
Sbjct: 1077 DNCEDDVDECA--SQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGP 1134
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQA----PC-RNYAGG 506
C G CV+L+G FRC CP GY G RC D +EC ++G C A C ++ GG
Sbjct: 1135 RCLHNGTCVDLVGGFRCTCPPGY----TGLRCEADINEC-RSGACHAAHTRDCLQDPGGG 1189
Query: 507 YRCDCPVG 530
+RC C G
Sbjct: 1190 FRCLCHAG 1197
Score = 78.6 bits (185), Expect = 1e-14
Identities = 64/180 (35%), Positives = 86/180 (47%), Gaps = 10/180 (5%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGR-DECAVRPPPCDQ--LCHNTDGSYDCLCRTGY--ELDED 185
G F C C PGY+ GR R DEC V PC C NT GS+ C C GY L E+
Sbjct: 100 GRFLCSCPPGYQ--GRSCRSDVDECRV-GEPCRHGGTCLNTPGSFRCQCPAGYTGPLCEN 156
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
A C R+ TC+Q + + +Y+C+C G+E G C V++++C C + G
Sbjct: 157 PAVPCAPSPC-RNGGTCRQ---SGDLTYDCACLPGFE--GQNCEVNVDDCPGHR-CLNGG 209
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCV-DRDEC-AQTGRCQ--APCRNYAGGYRCDCPVG 530
CV+ + ++ C CP + G C D DEC Q C C N GG+ C C G
Sbjct: 210 TCVDGVNTYNCQCPPEW----TGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNG 265
Score = 78.2 bits (184), Expect = 2e-14
Identities = 54/176 (30%), Positives = 70/176 (39%), Gaps = 6/176 (3%)
Frame = +3
Query: 21 GSFRCVCGPGYR-PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
G FRCVC PG+ P RD C +P C + + C C G + G C
Sbjct: 674 GGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQ----GRQC 729
Query: 198 RDVDECERDTHTCQQICSNTEGSYE-CSCEDGYEKRGDACV-DINECHEEGVCPSPGRCV 371
+ C + C + G CSC G++ G C D++EC C G C
Sbjct: 730 ELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQ--GPRCQQDVDECAGPAPCGPHGICT 787
Query: 372 NLLGSFRCVCPRGY---RLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
NL GSF C C GY D + C D + C G CQ + G + C C G
Sbjct: 788 NLAGSFSCTCHGGYTGPSCDQDINDC-DPNPCLNGGSCQ----DGVGSFSCSCLPG 838
Score = 75.8 bits (178), Expect = 1e-13
Identities = 54/172 (31%), Positives = 78/172 (45%), Gaps = 6/172 (3%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNTDGSYDCLCRTGYELDEDGANC-RD 203
C C G++ R + DECA P PC +C N GS+ C C GY G +C +D
Sbjct: 756 CSCPQGWQ-GPRCQQDVDECA-GPAPCGPHGICTNLAGSFSCTCHGGYT----GPSCDQD 809
Query: 204 VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSPGRCVNLL 380
+++C+ + C + GS+ CSC G+ G C D++EC C PG C + +
Sbjct: 810 INDCDPNPCLNGGSCQDGVGSFSCSCLPGFA--GPRCARDVDECLSNP-C-GPGTCTDHV 865
Query: 381 GSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ-APCRNYAGGYRCDCPVG 530
SF C CP GY G C D +C+ + C + + C C G
Sbjct: 866 ASFTCTCPPGY----GGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPG 913
Score = 71.3 bits (167), Expect = 2e-12
Identities = 56/176 (31%), Positives = 76/176 (43%), Gaps = 6/176 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N GSF C C GY + ++C P C + GS+ C C G+ G
Sbjct: 788 NLAGSFSCTCHGGYTGPSCD-QDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFA----GP 842
Query: 192 NC-RDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSPG 362
C RDVDEC ++ C C++ S+ C+C GY G C D+ +C C + G
Sbjct: 843 RCARDVDECL--SNPCGPGTCTDHVASFTCTCPPGYG--GFHCEQDLPDCSPSS-CFNGG 897
Query: 363 RCVNLLGSFRCVCPRGY---RLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
CV+ + SF C+C GY E C+ R C G C A G+RC C
Sbjct: 898 TCVDGVNSFSCLCRPGYTGAHCQHEADPCLSR-PCLHGGVCSAA----HPGFRCTC 948
Score = 69.7 bits (163), Expect = 6e-12
Identities = 61/188 (32%), Positives = 77/188 (40%), Gaps = 14/188 (7%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
V+ + SF C+C PGY A D C RP +C + C C + G
Sbjct: 900 VDGVNSFSCLCRPGYTGA-HCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFT----G 954
Query: 189 ANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINE--CHE------- 338
C+ VD C R C T G+Y C C G+ G C DI C E
Sbjct: 955 PQCQTLVDWCSRQPCQNGGRCVQT-GAY-CLCPPGWS--GRLC-DIRSLPCREAAAQIGV 1009
Query: 339 --EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DEC-AQTGRCQAPCRNYAGG 506
E +C + G+CV+ S CVCP G G+ C D C AQ + CR Y GG
Sbjct: 1010 RLEQLCQAGGQCVDEDSSHYCVCPEG----RTGSHCEQEVDPCLAQPCQHGGTCRGYMGG 1065
Query: 507 YRCDCPVG 530
Y C+C G
Sbjct: 1066 YMCECLPG 1073
Score = 65.7 bits (153), Expect = 1e-10
Identities = 42/133 (31%), Positives = 58/133 (43%), Gaps = 6/133 (4%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNT----DGSYDCLCRTGYELDEDGANCR 200
C+C PG+ G + D C P +C ++ + C C G+ G +C
Sbjct: 25 CLCPPGW--VGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFR----GPDCS 78
Query: 201 DVDECERDTHTCQQICS-NTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVN 374
D C CS +G + CSC GY+ G +C D++EC C G C+N
Sbjct: 79 LPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQ--GRSCRSDVDECRVGEPCRHGGTCLN 136
Query: 375 LLGSFRCVCPRGY 413
GSFRC CP GY
Sbjct: 137 TPGSFRCQCPAGY 149
Score = 60.9 bits (141), Expect = 3e-09
Identities = 49/179 (27%), Positives = 72/179 (40%), Gaps = 5/179 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ + + C C G V D+CA P +C + YDC+C+ G+ G
Sbjct: 558 LDLVDKYLCRCPSGTTGVNCEVN-IDDCASNPCTFG-VCRDGINRYDCVCQPGFT----G 611
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGR 365
C +++EC C + E + C C G C+ + C S G
Sbjct: 612 PLCNVEINECASSPCGEGGSCVDGENGFRCLCPPG--SLPPLCLPPSHPCAHEPC-SHGI 668
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARC---VDRDEC-AQTGRCQAPCRNYAGGYRCDCPVG 530
C + G FRCVC G+ G RC + RD C +Q R C + G+ C CP G
Sbjct: 669 CYDAPGGFRCVCEPGW----SGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPG 723
Score = 58.4 bits (135), Expect = 2e-08
Identities = 51/175 (29%), Positives = 73/175 (41%), Gaps = 5/175 (2%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRD 203
+ C C G+ R D+C+ P PC C + S+ C C GY G C
Sbjct: 489 YECRCAEGFEGTLCD-RNVDDCS--PDPCHHGRCVDGIASFSCACAPGYT----GTRCES 541
Query: 204 -VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNL 377
VDEC C + Y C C G G C V+I++C C G C +
Sbjct: 542 QVDECRSQPCRHGGKCLDLVDKYLCRCPSG--TTGVNCEVNIDDC-ASNPCTF-GVCRDG 597
Query: 378 LGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQA-PCRNYAGGYRCDCPVGTV 536
+ + CVC G+ G C V+ +ECA + + C + G+RC CP G++
Sbjct: 598 INRYDCVCQPGFT----GPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSL 648
Score = 55.6 bits (128), Expect = 1e-07
Identities = 42/135 (31%), Positives = 54/135 (40%), Gaps = 8/135 (5%)
Frame = +3
Query: 150 CLCRTGYELDEDGANCRDVDECERDTHTCQQICSNT----EGSYECSCEDGYEKRGDACV 317
CLC G+ G C+ D C + +C ++ + C C G+ RG C
Sbjct: 25 CLCPPGWV----GERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGF--RGPDCS 78
Query: 318 DINECHEEGVCPSPGRC-VNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--AP 485
+ C C RC V G F C CP GY +G C D DEC C+
Sbjct: 79 LPDPCLSSP-CAHGARCSVGPDGRFLCSCPPGY----QGRSCRSDVDECRVGEPCRHGGT 133
Query: 486 CRNYAGGYRCDCPVG 530
C N G +RC CP G
Sbjct: 134 CLNTPGSFRCQCPAG 148
Score = 54.0 bits (124), Expect = 3e-07
Identities = 54/182 (29%), Positives = 75/182 (41%), Gaps = 12/182 (6%)
Frame = +3
Query: 27 FRCVCGPGYR-PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYE---LDEDGAN 194
FRC C + P + + D C+ +P C T G+Y CLC G+ D
Sbjct: 944 FRCTCLESFTGPQCQTLV--DWCSRQPCQNGGRCVQT-GAY-CLCPPGWSGRLCDIRSLP 999
Query: 195 CRDVDEC--ERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSP 359
CR+ R CQ C + + S+ C C +G + G C +++ C + C
Sbjct: 1000 CREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEG--RTGSHCEQEVDPCLAQP-CQHG 1056
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ--APCRNYAGGYRCDCPVG 530
G C +G + C C GY G C D DECA CQ C + Y C CP G
Sbjct: 1057 GTCRGYMGGYMCECLPGYN----GDNCEDDVDECASQP-CQHGGSCIDLVARYLCSCPPG 1111
Query: 531 TV 536
T+
Sbjct: 1112 TL 1113
Score = 49.2 bits (112), Expect = 9e-06
Identities = 51/195 (26%), Positives = 73/195 (37%), Gaps = 21/195 (10%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPP-----PC--DQLCHNTDGSYDCLCRTG 167
++ + + C C PG + D+C PP C + C + G + C C G
Sbjct: 1098 IDLVARYLCSCPPGTLGVLCEIN-EDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPG 1156
Query: 168 YELDEDGANCR-DVDECERDT----HTCQQICSNTEGSYECSCEDGYEKRGDACVDI--- 323
Y G C D++EC HT + + G + C C G+ G C +
Sbjct: 1157 YT----GLRCEADINECRSGACHAAHT-RDCLQDPGGGFRCLCHAGFS--GPRCQTVLSP 1209
Query: 324 ---NECHEEGVC-PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQA--P 485
C G C PSPG L +F C C + + G RC + +C P
Sbjct: 1210 CESQPCQHGGQCRPSPGPGGGL--TFTCHCAQPFW----GPRCERVARSCRELQCPVGVP 1263
Query: 486 CRNYAGGYRCDCPVG 530
C+ G RC CP G
Sbjct: 1264 CQQTPRGPRCACPPG 1278
>AB209447-1|BAD92684.1| 1289|Homo sapiens Notch homolog 3 variant
protein.
Length = 1289
Score = 85.4 bits (202), Expect = 1e-16
Identities = 58/179 (32%), Positives = 82/179 (45%), Gaps = 4/179 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ IG F C+C G+ V DEC P +C + + C C +G+ G
Sbjct: 450 LDRIGQFTCICMAGFTGTYCEV-DIDECQSSPCVNGGVCKDRVNGFSCTCPSGFS----G 504
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSPG 362
+ C+ DVDEC C + YEC C +G+E G C ++++C + C G
Sbjct: 505 STCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFE--GTLCDRNVDDCSPDP-CHH-G 560
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDR-DEC-AQTGRCQAPCRNYAGGYRCDCPVGT 533
RCV+ + SF C C GY G RC + DEC +Q R C + Y C CP GT
Sbjct: 561 RCVDGIASFSCACAPGY----TGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGT 615
Score = 83.4 bits (197), Expect = 5e-16
Identities = 64/185 (34%), Positives = 81/185 (43%), Gaps = 11/185 (5%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ--LCHNT-DGSYDCLCRTGYELD 179
+NT GSFRC C GY CA P PC C + D +YDC C G+E
Sbjct: 178 LNTPGSFRCQCPAGYT-GPLCENPAVPCA--PSPCRNGGTCRQSGDLTYDCACLPGFE-- 232
Query: 180 EDGANCR-DVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACV-DINECH-EEG 344
G NC +VD+C H C C + +Y C C E G C D++EC +
Sbjct: 233 --GQNCEVNVDDCPG--HRCLNGGTCVDGVNTYNCQCPP--EWTGQFCTEDVDECQLQPN 286
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRC--QAPCRNYAGGYRC 515
C + G C N LG CVC G+ G C D+CA T C A C + + C
Sbjct: 287 ACHNGGTCFNTLGGHSCVCVNGW----TGESCSQNIDDCA-TAVCFHGATCHDRVASFYC 341
Query: 516 DCPVG 530
CP+G
Sbjct: 342 ACPMG 346
Score = 81.4 bits (192), Expect = 2e-15
Identities = 58/179 (32%), Positives = 78/179 (43%), Gaps = 3/179 (1%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
R V+ I SF C C PGY R DEC +P C + Y C C +G
Sbjct: 561 RCVDGIASFSCACAPGYTGT-RCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSG----T 615
Query: 183 DGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPS 356
G NC ++D+C + T +C + Y+C C+ G+ G C V+INEC C
Sbjct: 616 TGVNCEVNIDDCASNPCTFG-VCRDGINRYDCVCQPGFT--GPLCNVEINEC-ASSPCGE 671
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDE-CAQTGRCQAPCRNYAGGYRCDCPVG 530
G CV+ FRC+CP G + C+ CA C + GG+RC C G
Sbjct: 672 GGSCVDGENGFRCLCPPG----SLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPG 726
Score = 81.0 bits (191), Expect = 3e-15
Identities = 53/180 (29%), Positives = 77/180 (42%), Gaps = 4/180 (2%)
Frame = +3
Query: 3 RGVNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDE 182
R VNT GSF C CG GY R +EC P C + G + C+C G+
Sbjct: 410 RCVNTQGSFLCQCGRGY-TGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGF---- 464
Query: 183 DGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPS 356
G C D+DEC+ +C + + C+C G+ G C +D++EC C +
Sbjct: 465 TGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFS--GSTCQLDVDEC-ASTPCRN 521
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDR--DECAQTGRCQAPCRNYAGGYRCDCPVG 530
+CV+ + C C G+ EG C DR D+C+ C + + C C G
Sbjct: 522 GAKCVDQPDGYECRCAEGF----EGTLC-DRNVDDCSPDPCHHGRCVDGIASFSCACAPG 576
Score = 80.2 bits (189), Expect = 4e-15
Identities = 61/180 (33%), Positives = 77/180 (42%), Gaps = 7/180 (3%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
NT+G CVC G+ + D+CA CH+ S+ C C G + G
Sbjct: 296 NTLGGHSCVCVNGWTGESCS-QNIDDCATAVCFHGATCHDRVASFYCACPMG----KTGL 350
Query: 192 NCRDVDECERDTHTCQQICSNT--EGSYECSCEDGYEKRGDAC-VDINECH-EEGVCPSP 359
C D C + IC G C+C G+ G AC D++EC C
Sbjct: 351 LCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFT--GGACDQDVDECSIGANPCEHL 408
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRC--QAPCRNYAGGYRCDCPVG 530
GRCVN GSF C C RGY G RC D +EC +G C QA C + G + C C G
Sbjct: 409 GRCVNTQGSFLCQCGRGY----TGPRCETDVNECL-SGPCRNQATCLDRIGQFTCICMAG 463
Score = 79.4 bits (187), Expect = 8e-15
Identities = 65/188 (34%), Positives = 79/188 (42%), Gaps = 14/188 (7%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
V+ S CVC G R + D C +P C G Y C C GY +G
Sbjct: 1013 VDEDSSHYCVCPEG-RTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGY----NG 1067
Query: 189 ANCRD-VDECERDTHTCQQ--ICSNTEGSYECSCEDGY-----EKRGDACVDINECHEEG 344
NC D VDEC + CQ C + Y CSC G E D C
Sbjct: 1068 DNCEDDVDECA--SQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGP 1125
Query: 345 VCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQA----PC-RNYAGG 506
C G CV+L+G FRC CP GY G RC D +EC ++G C A C ++ GG
Sbjct: 1126 RCLHNGTCVDLVGGFRCTCPPGY----TGLRCEADINEC-RSGACHAAHTRDCLQDPGGG 1180
Query: 507 YRCDCPVG 530
+RC C G
Sbjct: 1181 FRCLCHAG 1188
Score = 78.6 bits (185), Expect = 1e-14
Identities = 64/180 (35%), Positives = 86/180 (47%), Gaps = 10/180 (5%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGR-DECAVRPPPCDQ--LCHNTDGSYDCLCRTGY--ELDED 185
G F C C PGY+ GR R DEC V PC C NT GS+ C C GY L E+
Sbjct: 143 GRFLCSCPPGYQ--GRSCRSDVDECRV-GEPCRHGGTCLNTPGSFRCQCPAGYTGPLCEN 199
Query: 186 GANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
A C R+ TC+Q + + +Y+C+C G+E G C V++++C C + G
Sbjct: 200 PAVPCAPSPC-RNGGTCRQ---SGDLTYDCACLPGFE--GQNCEVNVDDCPGHR-CLNGG 252
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCV-DRDEC-AQTGRCQ--APCRNYAGGYRCDCPVG 530
CV+ + ++ C CP + G C D DEC Q C C N GG+ C C G
Sbjct: 253 TCVDGVNTYNCQCPPEW----TGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNG 308
Score = 69.7 bits (163), Expect = 6e-12
Identities = 61/188 (32%), Positives = 77/188 (40%), Gaps = 14/188 (7%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
V+ + SF C+C PGY A D C RP +C + C C + G
Sbjct: 891 VDGVNSFSCLCRPGYTGA-HCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFT----G 945
Query: 189 ANCRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINE--CHE------- 338
C+ VD C R C T G+Y C C G+ G C DI C E
Sbjct: 946 PQCQTLVDWCSRQPCQNGGRCVQT-GAY-CLCPPGWS--GRLC-DIRSLPCREAAAQIGV 1000
Query: 339 --EGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DEC-AQTGRCQAPCRNYAGG 506
E +C + G+CV+ S CVCP G G+ C D C AQ + CR Y GG
Sbjct: 1001 RLEQLCQAGGQCVDEDSSHYCVCPEG----RTGSHCEQEVDPCLAQPCQHGGTCRGYMGG 1056
Query: 507 YRCDCPVG 530
Y C+C G
Sbjct: 1057 YMCECLPG 1064
Score = 65.7 bits (153), Expect = 1e-10
Identities = 42/133 (31%), Positives = 58/133 (43%), Gaps = 6/133 (4%)
Frame = +3
Query: 33 CVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNT----DGSYDCLCRTGYELDEDGANCR 200
C+C PG+ G + D C P +C ++ + C C G+ G +C
Sbjct: 68 CLCPPGW--VGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFR----GPDCS 121
Query: 201 DVDECERDTHTCQQICS-NTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVN 374
D C CS +G + CSC GY+ G +C D++EC C G C+N
Sbjct: 122 LPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQ--GRSCRSDVDECRVGEPCRHGGTCLN 179
Query: 375 LLGSFRCVCPRGY 413
GSFRC CP GY
Sbjct: 180 TPGSFRCQCPAGY 192
Score = 64.1 bits (149), Expect = 3e-10
Identities = 60/193 (31%), Positives = 80/193 (41%), Gaps = 18/193 (9%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCD-QLCHN----TDG--SYDCLCRTGYEL 176
+ SF C C PGY G C P C C N DG S+ CLCR GY
Sbjct: 856 VASFTCTCPPGY--------GGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGY-- 905
Query: 177 DEDGANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCP 353
GA+C+ + D C +CS + C+C + + G C + + C
Sbjct: 906 --TGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESF--TGPQCQTLVDWCSRQPCQ 961
Query: 354 SPGRCVNLLGSFRCVCPRGY--RL-DAEGARCVDRDECAQTG-----RCQA--PCRNYAG 503
+ GRCV G++ C+CP G+ RL D C R+ AQ G CQA C +
Sbjct: 962 NGGRCVQ-TGAY-CLCPPGWSGRLCDIRSLPC--REAAAQIGVRLEQLCQAGGQCVDEDS 1017
Query: 504 GYRCDCPVGTVRS 542
+ C CP G S
Sbjct: 1018 SHYCVCPEGRTGS 1030
Score = 62.1 bits (144), Expect = 1e-09
Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 8/172 (4%)
Frame = +3
Query: 30 RCVCGPGYRPAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCLCRTGYELDEDGANC-R 200
RC PG P +G + PC C + GS+ C C G+ G C R
Sbjct: 788 RCESAPGQLPVCSCPQGWQD------PCLNGGSCQDGVGSFSCSCLPGFA----GPRCAR 837
Query: 201 DVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSPGRCVN 374
DVDEC ++ C C++ S+ C+C GY G C D+ +C C + G CV+
Sbjct: 838 DVDECL--SNPCGPGTCTDHVASFTCTCPPGYG--GFHCEQDLPDCSPSS-CFNGGTCVD 892
Query: 375 LLGSFRCVCPRGY---RLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDC 521
+ SF C+C GY E C+ R C G C A G+RC C
Sbjct: 893 GVNSFSCLCRPGYTGAHCQHEADPCLSR-PCLHGGVCSAA----HPGFRCTC 939
Score = 60.9 bits (141), Expect = 3e-09
Identities = 49/179 (27%), Positives = 72/179 (40%), Gaps = 5/179 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ + + C C G V D+CA P +C + YDC+C+ G+ G
Sbjct: 601 LDLVDKYLCRCPSGTTGVNCEVN-IDDCASNPCTFG-VCRDGINRYDCVCQPGFT----G 654
Query: 189 ANCR-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGR 365
C +++EC C + E + C C G C+ + C S G
Sbjct: 655 PLCNVEINECASSPCGEGGSCVDGENGFRCLCPPG--SLPPLCLPPSHPCAHEPC-SHGI 711
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARC---VDRDEC-AQTGRCQAPCRNYAGGYRCDCPVG 530
C + G FRCVC G+ G RC + RD C +Q R C + G+ C CP G
Sbjct: 712 CYDAPGGFRCVCEPGW----SGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPG 766
Score = 59.3 bits (137), Expect = 9e-09
Identities = 54/197 (27%), Positives = 72/197 (36%), Gaps = 29/197 (14%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRD 203
FRC+C PG P + CA P C +C++ G + C+C G+ G C
Sbjct: 682 FRCLCPPGSLPP-LCLPPSHPCAHEP--CSHGICYDAPGGFRCVCEPGWS----GPRCSQ 734
Query: 204 V---DECERDTHTCQQICSNTEGSYECSCEDGYEKRG----DACVDINECHEEG------ 344
D CE CS+ + C+C G + R C N C G
Sbjct: 735 SLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTP-NPCEHGGRCESAP 793
Query: 345 ----VCPSP----------GRCVNLLGSFRCVCPRGYRLDAEGARCV-DRDECAQTGRCQ 479
VC P G C + +GSF C C G+ G RC D DEC
Sbjct: 794 GQLPVCSCPQGWQDPCLNGGSCQDGVGSFSCSCLPGF----AGPRCARDVDECLSNPCGP 849
Query: 480 APCRNYAGGYRCDCPVG 530
C ++ + C CP G
Sbjct: 850 GTCTDHVASFTCTCPPG 866
Score = 58.4 bits (135), Expect = 2e-08
Identities = 51/175 (29%), Positives = 73/175 (41%), Gaps = 5/175 (2%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGANCRD 203
+ C C G+ R D+C+ P PC C + S+ C C GY G C
Sbjct: 532 YECRCAEGFEGTLCD-RNVDDCS--PDPCHHGRCVDGIASFSCACAPGYT----GTRCES 584
Query: 204 -VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNL 377
VDEC C + Y C C G G C V+I++C C G C +
Sbjct: 585 QVDECRSQPCRHGGKCLDLVDKYLCRCPSG--TTGVNCEVNIDDC-ASNPCTF-GVCRDG 640
Query: 378 LGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQA-PCRNYAGGYRCDCPVGTV 536
+ + CVC G+ G C V+ +ECA + + C + G+RC CP G++
Sbjct: 641 INRYDCVCQPGFT----GPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSL 691
Score = 57.6 bits (133), Expect = 3e-08
Identities = 49/173 (28%), Positives = 64/173 (36%), Gaps = 2/173 (1%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQ-LCHNTDGSYDCLCRTGYELDEDGAN 194
+GSF C C PG+ R R DEC PC C + S+ C C GY G +
Sbjct: 819 VGSFSCSCLPGF-AGPRCARDVDECLSN--PCGPGTCTDHVASFTCTCPPGY----GGFH 871
Query: 195 C-RDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCV 371
C +D+ +C + C + S+ C C GY G C + C G C
Sbjct: 872 CEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGY--TGAHCQHEADPCLSRPCLHGGVCS 929
Query: 372 NLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
FRC C + G +C + CQ R G C CP G
Sbjct: 930 AAHPGFRCTCLESF----TGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPG 978
Score = 57.2 bits (132), Expect = 4e-08
Identities = 55/196 (28%), Positives = 73/196 (37%), Gaps = 26/196 (13%)
Frame = +3
Query: 21 GSFRCVCGPGYR-PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYE------LD 179
G FRCVC PG+ P RD C +P C + + C C G + L
Sbjct: 717 GGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLS 776
Query: 180 EDGAN-CRDVDECER-----DTHTCQQ----------ICSNTEGSYECSCEDGYEKRGDA 311
N C CE +C Q C + GS+ CSC G+ G
Sbjct: 777 PCTPNPCEHGGRCESAPGQLPVCSCPQGWQDPCLNGGSCQDGVGSFSCSCLPGFA--GPR 834
Query: 312 CV-DINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ-A 482
C D++EC C PG C + + SF C CP GY G C D +C+ +
Sbjct: 835 CARDVDECLSNP-C-GPGTCTDHVASFTCTCPPGY----GGFHCEQDLPDCSPSSCFNGG 888
Query: 483 PCRNYAGGYRCDCPVG 530
C + + C C G
Sbjct: 889 TCVDGVNSFSCLCRPG 904
Score = 55.6 bits (128), Expect = 1e-07
Identities = 42/135 (31%), Positives = 54/135 (40%), Gaps = 8/135 (5%)
Frame = +3
Query: 150 CLCRTGYELDEDGANCRDVDECERDTHTCQQICSNT----EGSYECSCEDGYEKRGDACV 317
CLC G+ G C+ D C + +C ++ + C C G+ RG C
Sbjct: 68 CLCPPGWV----GERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGF--RGPDCS 121
Query: 318 DINECHEEGVCPSPGRC-VNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--AP 485
+ C C RC V G F C CP GY +G C D DEC C+
Sbjct: 122 LPDPCLSSP-CAHGARCSVGPDGRFLCSCPPGY----QGRSCRSDVDECRVGEPCRHGGT 176
Query: 486 CRNYAGGYRCDCPVG 530
C N G +RC CP G
Sbjct: 177 CLNTPGSFRCQCPAG 191
Score = 54.0 bits (124), Expect = 3e-07
Identities = 54/182 (29%), Positives = 75/182 (41%), Gaps = 12/182 (6%)
Frame = +3
Query: 27 FRCVCGPGYR-PAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYE---LDEDGAN 194
FRC C + P + + D C+ +P C T G+Y CLC G+ D
Sbjct: 935 FRCTCLESFTGPQCQTLV--DWCSRQPCQNGGRCVQT-GAY-CLCPPGWSGRLCDIRSLP 990
Query: 195 CRDVDEC--ERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSP 359
CR+ R CQ C + + S+ C C +G + G C +++ C + C
Sbjct: 991 CREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEG--RTGSHCEQEVDPCLAQP-CQHG 1047
Query: 360 GRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ--APCRNYAGGYRCDCPVG 530
G C +G + C C GY G C D DECA CQ C + Y C CP G
Sbjct: 1048 GTCRGYMGGYMCECLPGYN----GDNCEDDVDECASQP-CQHGGSCIDLVARYLCSCPPG 1102
Query: 531 TV 536
T+
Sbjct: 1103 TL 1104
Score = 49.2 bits (112), Expect = 9e-06
Identities = 51/195 (26%), Positives = 73/195 (37%), Gaps = 21/195 (10%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPP-----PC--DQLCHNTDGSYDCLCRTG 167
++ + + C C PG + D+C PP C + C + G + C C G
Sbjct: 1089 IDLVARYLCSCPPGTLGVLCEIN-EDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPG 1147
Query: 168 YELDEDGANCR-DVDECERDT----HTCQQICSNTEGSYECSCEDGYEKRGDACVDI--- 323
Y G C D++EC HT + + G + C C G+ G C +
Sbjct: 1148 YT----GLRCEADINECRSGACHAAHT-RDCLQDPGGGFRCLCHAGFS--GPRCQTVLSP 1200
Query: 324 ---NECHEEGVC-PSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQA--P 485
C G C PSPG L +F C C + + G RC + +C P
Sbjct: 1201 CESQPCQHGGQCRPSPGPGGGL--TFTCHCAQPFW----GPRCERVARSCRELQCPVGVP 1254
Query: 486 CRNYAGGYRCDCPVG 530
C+ G RC CP G
Sbjct: 1255 CQQTPRGPRCACPPG 1269
>AB231861-1|BAE19679.1| 1950|Homo sapiens low-density lipoprotein
receptor-related protein 4 protein.
Length = 1950
Score = 84.6 bits (200), Expect = 2e-16
Identities = 35/77 (45%), Positives = 46/77 (59%)
Frame = +3
Query: 78 GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNT 257
G + C V C Q C G+ C C TGY L EDG C+DV+EC + + C Q C+N+
Sbjct: 402 GEENCNVNNGGCAQKCQMVRGAVQCTCHTGYRLTEDGHTCQDVNECAEEGY-CSQGCTNS 460
Query: 258 EGSYECSCEDGYEKRGD 308
EG+++C CE GYE R D
Sbjct: 461 EGAFQCWCETGYELRPD 477
Score = 67.3 bits (157), Expect = 3e-11
Identities = 34/88 (38%), Positives = 44/88 (50%), Gaps = 5/88 (5%)
Frame = +3
Query: 192 NCRD---VDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPS 356
NCR + C + C Q C G+ +C+C GY + G C D+NEC EEG C S
Sbjct: 396 NCRPRTGEENCNVNNGGCAQKCQMVRGAVQCTCHTGYRLTEDGHTCQDVNECAEEGYC-S 454
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARC 440
G C N G+F+C C GY L + C
Sbjct: 455 QG-CTNSEGAFQCWCETGYELRPDRRSC 481
Score = 64.5 bits (150), Expect = 2e-10
Identities = 52/178 (29%), Positives = 73/178 (41%), Gaps = 6/178 (3%)
Frame = +3
Query: 15 TIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDC-----LCRTGYELD 179
T FRC G R + R G D+CA ++ C NT GS C LC G +
Sbjct: 319 TAEQFRCHSGRCVRLSWR-CDGEDDCADNSD--EENCENT-GSPQCALDQFLCWNGRCIG 374
Query: 180 EDGANCRDVDEC-ERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPS 356
+ C V++C + + QQ C G C+ +G C
Sbjct: 375 QRKL-CNGVNDCGDNSDESPQQNCRPRTGEENCNVNNG------GCAQ------------ 415
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
+C + G+ +C C GYRL +G C D +ECA+ G C C N G ++C C G
Sbjct: 416 --KCQMVRGAVQCTCHTGYRLTEDGHTCQDVNECAEEGYCSQGCTNSEGAFQCWCETG 471
Score = 51.6 bits (118), Expect = 2e-06
Identities = 25/62 (40%), Positives = 34/62 (54%), Gaps = 2/62 (3%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
G+ +C C GYR G +D ECA C Q C N++G++ C C TGYEL D +
Sbjct: 422 GAVQCTCHTGYRLTEDGHTCQDVNECA-EEGYCSQGCTNSEGAFQCWCETGYELRPDRRS 480
Query: 195 CR 200
C+
Sbjct: 481 CK 482
Score = 35.1 bits (77), Expect = 0.17
Identities = 14/40 (35%), Positives = 18/40 (45%)
Frame = +3
Query: 78 GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
G ++C R C LC + C C TG +L DG C
Sbjct: 1357 GFNKCGSRNGGCSHLCLPRPSGFSCACPTGIQLKGDGKTC 1396
>AB084910-1|BAD83615.1| 1905|Homo sapiens low density lipoprotein
receptor-related protein 10 protein.
Length = 1905
Score = 84.6 bits (200), Expect = 2e-16
Identities = 35/77 (45%), Positives = 46/77 (59%)
Frame = +3
Query: 78 GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNT 257
G + C V C Q C G+ C C TGY L EDG C+DV+EC + + C Q C+N+
Sbjct: 354 GEENCNVNNGGCAQKCQMVRGAVQCTCHTGYRLTEDGHTCQDVNECAEEGY-CSQGCTNS 412
Query: 258 EGSYECSCEDGYEKRGD 308
EG+++C CE GYE R D
Sbjct: 413 EGAFQCWCETGYELRPD 429
Score = 67.3 bits (157), Expect = 3e-11
Identities = 34/88 (38%), Positives = 44/88 (50%), Gaps = 5/88 (5%)
Frame = +3
Query: 192 NCRD---VDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPS 356
NCR + C + C Q C G+ +C+C GY + G C D+NEC EEG C S
Sbjct: 348 NCRPRTGEENCNVNNGGCAQKCQMVRGAVQCTCHTGYRLTEDGHTCQDVNECAEEGYC-S 406
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARC 440
G C N G+F+C C GY L + C
Sbjct: 407 QG-CTNSEGAFQCWCETGYELRPDRRSC 433
Score = 64.5 bits (150), Expect = 2e-10
Identities = 52/178 (29%), Positives = 73/178 (41%), Gaps = 6/178 (3%)
Frame = +3
Query: 15 TIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDC-----LCRTGYELD 179
T FRC G R + R G D+CA ++ C NT GS C LC G +
Sbjct: 271 TAEQFRCHSGRCVRLSWR-CDGEDDCADNSD--EENCENT-GSPQCALDQFLCWNGRCIG 326
Query: 180 EDGANCRDVDEC-ERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPS 356
+ C V++C + + QQ C G C+ +G C
Sbjct: 327 QRKL-CNGVNDCGDNSDESPQQNCRPRTGEENCNVNNG------GCAQ------------ 367
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
+C + G+ +C C GYRL +G C D +ECA+ G C C N G ++C C G
Sbjct: 368 --KCQMVRGAVQCTCHTGYRLTEDGHTCQDVNECAEEGYCSQGCTNSEGAFQCWCETG 423
Score = 51.6 bits (118), Expect = 2e-06
Identities = 25/62 (40%), Positives = 34/62 (54%), Gaps = 2/62 (3%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
G+ +C C GYR G +D ECA C Q C N++G++ C C TGYEL D +
Sbjct: 374 GAVQCTCHTGYRLTEDGHTCQDVNECA-EEGYCSQGCTNSEGAFQCWCETGYELRPDRRS 432
Query: 195 CR 200
C+
Sbjct: 433 CK 434
Score = 35.1 bits (77), Expect = 0.17
Identities = 14/40 (35%), Positives = 18/40 (45%)
Frame = +3
Query: 78 GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
G ++C R C LC + C C TG +L DG C
Sbjct: 1309 GFNKCGSRNGGCSHLCLPRPSGFSCACPTGIQLKGDGKTC 1348
>AB011540-1|BAA32468.1| 1576|Homo sapiens MEGF7 protein.
Length = 1576
Score = 84.6 bits (200), Expect = 2e-16
Identities = 35/77 (45%), Positives = 46/77 (59%)
Frame = +3
Query: 78 GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQICSNT 257
G + C V C Q C G+ C C TGY L EDG C+DV+EC + + C Q C+N+
Sbjct: 25 GEENCNVNNGGCAQKCQMVRGAVQCTCHTGYRLTEDGHTCQDVNECAEEGY-CSQGCTNS 83
Query: 258 EGSYECSCEDGYEKRGD 308
EG+++C CE GYE R D
Sbjct: 84 EGAFQCWCETGYELRPD 100
Score = 67.3 bits (157), Expect = 3e-11
Identities = 34/88 (38%), Positives = 44/88 (50%), Gaps = 5/88 (5%)
Frame = +3
Query: 192 NCRD---VDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINECHEEGVCPS 356
NCR + C + C Q C G+ +C+C GY + G C D+NEC EEG C S
Sbjct: 19 NCRPRTGEENCNVNNGGCAQKCQMVRGAVQCTCHTGYRLTEDGHTCQDVNECAEEGYC-S 77
Query: 357 PGRCVNLLGSFRCVCPRGYRLDAEGARC 440
G C N G+F+C C GY L + C
Sbjct: 78 QG-CTNSEGAFQCWCETGYELRPDRRSC 104
Score = 57.6 bits (133), Expect = 3e-08
Identities = 22/56 (39%), Positives = 31/56 (55%)
Frame = +3
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
+C + G+ +C C GYRL +G C D +ECA+ G C C N G ++C C G
Sbjct: 39 KCQMVRGAVQCTCHTGYRLTEDGHTCQDVNECAEEGYCSQGCTNSEGAFQCWCETG 94
Score = 51.6 bits (118), Expect = 2e-06
Identities = 25/62 (40%), Positives = 34/62 (54%), Gaps = 2/62 (3%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRD--ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
G+ +C C GYR G +D ECA C Q C N++G++ C C TGYEL D +
Sbjct: 45 GAVQCTCHTGYRLTEDGHTCQDVNECA-EEGYCSQGCTNSEGAFQCWCETGYELRPDRRS 103
Query: 195 CR 200
C+
Sbjct: 104 CK 105
Score = 35.1 bits (77), Expect = 0.17
Identities = 14/40 (35%), Positives = 18/40 (45%)
Frame = +3
Query: 78 GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
G ++C R C LC + C C TG +L DG C
Sbjct: 980 GFNKCGSRNGGCSHLCLPRPSGFSCACPTGIQLKGDGKTC 1019
>BC035784-1|AAH35784.1| 439|Homo sapiens hypothetical protein
FLJ37440 protein.
Length = 439
Score = 83.8 bits (198), Expect = 4e-16
Identities = 62/196 (31%), Positives = 78/196 (39%), Gaps = 20/196 (10%)
Frame = +3
Query: 6 GVNTIGSFRCVCGPGYRPAGRG--VRGRDECAVRPPPCDQLCHNTDGSYDCLC---RTGY 170
G +G VC P G RG EC+ +P C Y C+C RTG
Sbjct: 110 GFRLVGPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRTGN 169
Query: 171 ELDEDGANCRDVDECERDTHTCQQI-CSNTEGSYECSCEDGYEKRGDA----CVDINECH 335
D+ + C+ E + CSCE G+ G A C D+NEC
Sbjct: 170 RCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECE 229
Query: 336 EEGVCPSPG----RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQ--APCRN 494
G P CVN GS+RC CP GYR A+G C D DEC C C N
Sbjct: 230 LYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCIN 289
Query: 495 YAGGYRC---DCPVGT 533
G ++C +CP G+
Sbjct: 290 TGGSFQCVSPECPEGS 305
Score = 62.9 bits (146), Expect = 7e-10
Identities = 36/94 (38%), Positives = 41/94 (43%), Gaps = 5/94 (5%)
Frame = +3
Query: 99 RPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYE 272
RP C C NT GSY C C GY DG +C DVDEC C Q C NT GS++
Sbjct: 236 RPRLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQ 295
Query: 273 C---SCEDGYEKRGDACVDINECHEEGVCPSPGR 365
C C +G +C E CP R
Sbjct: 296 CVSPECPEGSGNVSYVKTSPFQC-ERNPCPMDSR 328
>AK094759-1|BAC04416.1| 439|Homo sapiens protein ( Homo sapiens
cDNA FLJ37440 fis, clone BRAWH2006405, weakly similar to
FIBULIN-1, ISOFORM C PRECURSOR. ).
Length = 439
Score = 83.8 bits (198), Expect = 4e-16
Identities = 62/196 (31%), Positives = 78/196 (39%), Gaps = 20/196 (10%)
Frame = +3
Query: 6 GVNTIGSFRCVCGPGYRPAGRG--VRGRDECAVRPPPCDQLCHNTDGSYDCLC---RTGY 170
G +G VC P G RG EC+ +P C Y C+C RTG
Sbjct: 110 GFRLVGPSSMVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRTGN 169
Query: 171 ELDEDGANCRDVDECERDTHTCQQI-CSNTEGSYECSCEDGYEKRGDA----CVDINECH 335
D+ + C+ E + CSCE G+ G A C D+NEC
Sbjct: 170 RCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECE 229
Query: 336 EEGVCPSPG----RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQ--APCRN 494
G P CVN GS+RC CP GYR A+G C D DEC C C N
Sbjct: 230 LYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCIN 289
Query: 495 YAGGYRC---DCPVGT 533
G ++C +CP G+
Sbjct: 290 TGGSFQCVSPECPEGS 305
Score = 62.9 bits (146), Expect = 7e-10
Identities = 36/94 (38%), Positives = 41/94 (43%), Gaps = 5/94 (5%)
Frame = +3
Query: 99 RPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYE 272
RP C C NT GSY C C GY DG +C DVDEC C Q C NT GS++
Sbjct: 236 RPRLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQ 295
Query: 273 C---SCEDGYEKRGDACVDINECHEEGVCPSPGR 365
C C +G +C E CP R
Sbjct: 296 CVSPECPEGSGNVSYVKTSPFQC-ERNPCPMDSR 328
>AC092645-2|AAY14854.1| 439|Homo sapiens unknown protein.
Length = 439
Score = 83.8 bits (198), Expect = 4e-16
Identities = 62/196 (31%), Positives = 78/196 (39%), Gaps = 20/196 (10%)
Frame = +3
Query: 6 GVNTIGSFRCVCGPGYRPAGRG--VRGRDECAVRPPPCDQLCHNTDGSYDCLC---RTGY 170
G +G VC P G RG EC+ +P C Y C+C RTG
Sbjct: 110 GFRLVGPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRTGN 169
Query: 171 ELDEDGANCRDVDECERDTHTCQQI-CSNTEGSYECSCEDGYEKRGDA----CVDINECH 335
D+ + C+ E + CSCE G+ G A C D+NEC
Sbjct: 170 RCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECE 229
Query: 336 EEGVCPSPG----RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGR-CQ--APCRN 494
G P CVN GS+RC CP GYR A+G C D DEC C C N
Sbjct: 230 LYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCIN 289
Query: 495 YAGGYRC---DCPVGT 533
G ++C +CP G+
Sbjct: 290 TGGSFQCVSPECPEGS 305
Score = 62.9 bits (146), Expect = 7e-10
Identities = 36/94 (38%), Positives = 41/94 (43%), Gaps = 5/94 (5%)
Frame = +3
Query: 99 RPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYE 272
RP C C NT GSY C C GY DG +C DVDEC C Q C NT GS++
Sbjct: 236 RPRLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQ 295
Query: 273 C---SCEDGYEKRGDACVDINECHEEGVCPSPGR 365
C C +G +C E CP R
Sbjct: 296 CVSPECPEGSGNVSYVKTSPFQC-ERNPCPMDSR 328
>AB023961-1|BAB20317.1| 502|Homo sapiens notch4 protein.
Length = 502
Score = 83.8 bits (198), Expect = 4e-16
Identities = 57/179 (31%), Positives = 76/179 (42%), Gaps = 8/179 (4%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQL--CH-NTDGSYDCLCRTGYELDEDGAN 194
SF C C PG+ + D C P C + CH G C C G+ G
Sbjct: 99 SFLCTCLPGFTGERCQAKLEDPCP--PSFCSKRGRCHIQASGRPQCSCMPGWT----GEQ 152
Query: 195 CRDVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEE-GVCPSPGRC 368
C+ D C + +C T +C C G+E G AC D+NEC ++ G CP C
Sbjct: 153 CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFE--GHACERDVNECFQDPGPCPKGTSC 210
Query: 369 VNLLGSFRCVCP---RGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTV 536
N LGSF+C+CP G R + C R C+ G CQ + + C CP G +
Sbjct: 211 HNTLGSFQCLCPVGQEGPRCELRAGPCPPRG-CSNGGTCQLMPEKDSTFHLCLCPPGFI 268
Score = 80.6 bits (190), Expect = 3e-15
Identities = 60/180 (33%), Positives = 78/180 (43%), Gaps = 9/180 (5%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGA 191
N+ GSF CVC G+ D+C C + GS+ CLC G G
Sbjct: 333 NSAGSFHCVCVSGWGGTSCE-ENLDDCIAATCAPGSTCIDRVGSFSCLCPPG----RTGL 387
Query: 192 NCRDVDEC-ERDTHTCQQICSNT-EGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSP- 359
C D C + H Q +N GS C C+ GY G C D++EC PSP
Sbjct: 388 LCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYS--GPTCHQDLDECLMAQQGPSPC 445
Query: 360 ---GRCVNLLGSFRCVCPRGYRLDAEGARC-VDRDEC-AQTGRCQAPCRNYAGGYRCDCP 524
G C+N GSF C+CP GY G+RC D +EC +Q + C + + C CP
Sbjct: 446 EHGGSCLNTPGSFNCLCPPGY----TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCP 501
Score = 77.0 bits (181), Expect = 4e-14
Identities = 50/141 (35%), Positives = 67/141 (47%), Gaps = 9/141 (6%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNT--DGSYDCLCRTGYELDE 182
++ +GSF C+C PG G D C +P D C GS CLC+ GY
Sbjct: 370 IDRVGSFSCLCPPG--RTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGY---- 423
Query: 183 DGANC-RDVDEC---ERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC-VDINECHEE 341
G C +D+DEC ++ C+ C NT GS+ C C GY G C D NEC +
Sbjct: 424 SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY--TGSRCEADHNECLSQ 481
Query: 342 GVCPSPGRCVNLLGSFRCVCP 404
C C++LL +F C+CP
Sbjct: 482 -PCHPGSTCLDLLATFHCLCP 501
Score = 70.5 bits (165), Expect = 4e-12
Identities = 60/191 (31%), Positives = 83/191 (43%), Gaps = 18/191 (9%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCD----------QLCHNTDGSYD-CLC 158
NT+GSF+C+C G G R C +R PC QL D ++ CLC
Sbjct: 212 NTLGSFQCLCPVGQE----GPR----CELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLC 263
Query: 159 RTGYELDEDGANCR-DVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACVDINE 329
G+ G C + D C +H CQ C + +Y C C + + D D++E
Sbjct: 264 PPGFI----GPGCEVNPDNCV--SHQCQNGGTCQDGLDTYTCLCPETWTG-WDCSEDVDE 316
Query: 330 CHEEGV--CPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DEC-AQTGRCQAPCRNY 497
C +G C + G C N GSF CVC G+ G C + D+C A T + C +
Sbjct: 317 CEAQGPPHCRNGGTCQNSAGSFHCVCVSGW----GGTSCEENLDDCIAATCAPGSTCIDR 372
Query: 498 AGGYRCDCPVG 530
G + C CP G
Sbjct: 373 VGSFSCLCPPG 383
Score = 66.5 bits (155), Expect = 6e-11
Identities = 50/162 (30%), Positives = 70/162 (43%), Gaps = 13/162 (8%)
Frame = +3
Query: 84 DECAVRPPP-CDQ--LCHNTDGSYDCLCRTGYELDEDGANCRD-VDECERDTHTCQQICS 251
DEC + PP C C N+ GS+ C+C +G+ G +C + +D+C T C
Sbjct: 315 DECEAQGPPHCRNGGTCQNSAGSFHCVCVSGW----GGTSCEENLDDCIAATCAPGSTCI 370
Query: 252 NTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVN--LLGSFRCVCPRGYRLDA 425
+ GS+ C C G + G C + C + C +C L GS C+C GY
Sbjct: 371 DRVGSFSCLCPPG--RTGLLCHLEDMCLSQP-CHGDAQCSTNPLTGSTLCLCQPGY---- 423
Query: 426 EGARC-VDRDECAQTGRCQAPCR------NYAGGYRCDCPVG 530
G C D DEC + +PC N G + C CP G
Sbjct: 424 SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPG 465
>AK074396-1|BAB85069.1| 220|Homo sapiens protein ( Homo sapiens
cDNA FLJ23816 fis, clone HSI02685. ).
Length = 220
Score = 83.4 bits (197), Expect = 5e-16
Identities = 47/109 (43%), Positives = 59/109 (54%), Gaps = 6/109 (5%)
Frame = +3
Query: 156 CRTGYELDEDGANCRDVDECERDTHTCQQICSNTEGSYECSCEDGYE--KRGDACVDINE 329
C G+ + ++G C D+DEC R + CQ C NTEGSY+C C GY G C DINE
Sbjct: 11 CPPGF-IRQNGV-CTDLDEC-RVRNLCQHACRNTEGSYQCLCPAGYRLLPSGKNCQDINE 67
Query: 330 CHEEGVCPSPGR-CVNLLGSFRCV---CPRGYRLDAEGARCVDRDECAQ 464
C EE + PG+ C N GS++CV CP YR C R C+Q
Sbjct: 68 CEEESIECGPGQMCFNTRGSYQCVDTPCPATYRQGPSPGTCFRR--CSQ 114
Score = 82.6 bits (195), Expect = 8e-16
Identities = 38/84 (45%), Positives = 47/84 (55%), Gaps = 2/84 (2%)
Frame = +3
Query: 30 RCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCRDVD 209
R C PG+ DEC VR C C NT+GSY CLC GY L G NC+D++
Sbjct: 8 RAWCPPGFIRQNGVCTDLDECRVRNL-CQHACRNTEGSYQCLCPAGYRLLPSGKNCQDIN 66
Query: 210 ECERDTHTC--QQICSNTEGSYEC 275
ECE ++ C Q+C NT GSY+C
Sbjct: 67 ECEEESIECGPGQMCFNTRGSYQC 90
Score = 65.3 bits (152), Expect = 1e-10
Identities = 33/96 (34%), Positives = 46/96 (47%), Gaps = 6/96 (6%)
Frame = +3
Query: 279 CEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDRDEC 458
C G+ ++ C D++EC +C C N GS++C+CP GYRL G C D +EC
Sbjct: 11 CPPGFIRQNGVCTDLDECRVRNLCQHA--CRNTEGSYQCLCPAGYRLLPSGKNCQDINEC 68
Query: 459 AQTGRCQAP---CRNYAGGYRC---DCPVGTVRSPS 548
+ P C N G Y+C CP + PS
Sbjct: 69 EEESIECGPGQMCFNTRGSYQCVDTPCPATYRQGPS 104
Score = 49.2 bits (112), Expect = 9e-06
Identities = 24/54 (44%), Positives = 27/54 (50%)
Frame = +3
Query: 390 RCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVGTVRSPSG 551
R CP G+ + G C D DEC CQ CRN G Y+C CP G PSG
Sbjct: 8 RAWCPPGF-IRQNGV-CTDLDECRVRNLCQHACRNTEGSYQCLCPAGYRLLPSG 59
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/81 (34%), Positives = 38/81 (46%), Gaps = 7/81 (8%)
Frame = +3
Query: 12 NTIGSFRCVCGPGYR--PAGRGVRGRDECAVRPPPC--DQLCHNTDGSYDCL---CRTGY 170
NT GS++C+C GYR P+G+ + +EC C Q+C NT GSY C+ C Y
Sbjct: 40 NTEGSYQCLCPAGYRLLPSGKNCQDINECEEESIECGPGQMCFNTRGSYQCVDTPCPATY 99
Query: 171 ELDEDGANCRDVDECERDTHT 233
C C +D T
Sbjct: 100 RQGPSPGTC--FRRCSQDCGT 118
>U77720-1|AAC51323.1| 1214|Homo sapiens transmembrane protein Jagged
protein.
Length = 1214
Score = 82.6 bits (195), Expect = 8e-16
Identities = 57/175 (32%), Positives = 78/175 (44%), Gaps = 6/175 (3%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVR-GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
+ F+CVC P + G+ + +EC +P + C N SY C C G+ N
Sbjct: 380 VNGFKCVCPPQW--TGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDIN 437
Query: 195 CRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSPGRC 368
D + +C+ D C + Y C C GY GD C DI+EC C + G C
Sbjct: 438 INDCLGQCQNDAS-----CRDLVNGYRCICPPGYA--GDHCERDIDEC-ASNPCLNGGHC 489
Query: 369 VNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCP 524
N + F+C+CP G+ G C +D D C + CQ A C N A Y C CP
Sbjct: 490 QNEINRFQCLCPTGF----SGNLCQLDIDYC-EPNPCQNGAQCYNRASDYFCKCP 539
Score = 77.8 bits (183), Expect = 2e-14
Identities = 51/172 (29%), Positives = 73/172 (42%), Gaps = 4/172 (2%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-D 203
F C C PG+ D+C+ C + + C+C + G C+ D
Sbjct: 345 FECECSPGWTGPTCSTN-IDDCSPNNCSHGGTCQDLVNGFKCVCPPQWT----GKTCQLD 399
Query: 204 VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNLL 380
+ECE + C N SY C C G+ G C ++IN+C G C + C +L+
Sbjct: 400 ANECEAKPCVNAKSCKNLIASYYCDCLPGW--MGQNCDININDCL--GQCQNDASCRDLV 455
Query: 381 GSFRCVCPRGYRLDAEGARCV-DRDECAQTGRCQ-APCRNYAGGYRCDCPVG 530
+RC+CP GY G C D DECA C+N ++C CP G
Sbjct: 456 NGYRCICPPGY----AGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTG 503
Score = 67.3 bits (157), Expect = 3e-11
Identities = 48/172 (27%), Positives = 66/172 (38%), Gaps = 1/172 (0%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
+ +RC+C PGY R DECA P C N + CLC TG+ G C
Sbjct: 455 VNGYRCICPPGYA-GDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFS----GNLC 509
Query: 198 R-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVN 374
+ D+D CE + C N Y C C + YE G C + + C C
Sbjct: 510 QLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYE--GKNCSHLKDHCRTTPCEVIDSCTV 567
Query: 375 LLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
+ S EG R + + C G+C++ G + CDC G
Sbjct: 568 AMAS---------NDTPEGVRYISSNVCGPHGKCKS---QSGGKFTCDCNKG 607
Score = 65.7 bits (153), Expect = 1e-10
Identities = 39/142 (27%), Positives = 63/142 (44%), Gaps = 3/142 (2%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-R 200
+F+C+C G+ + C P C S+ C+C+ G+E G C +
Sbjct: 713 AFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWE----GPICAQ 768
Query: 201 DVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVN 374
+ ++C H C C + + Y C C G+ D ++INEC + C CV+
Sbjct: 769 NTNDC--SPHPCYNSGTCVDGDNWYRCECAPGF-AGPDCRININEC-QSSPCAFGATCVD 824
Query: 375 LLGSFRCVCPRGYRLDAEGARC 440
+ +RCVCP G+ GA+C
Sbjct: 825 EINGYRCVCPPGH----SGAKC 842
Score = 62.9 bits (146), Expect = 7e-10
Identities = 45/178 (25%), Positives = 70/178 (39%), Gaps = 4/178 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ + S++C+C G+ A D C+ P C + + C C+ G++ G
Sbjct: 632 IDGVNSYKCICSDGWEGAYCETNIND-CSQNPCHNGGTCRDLVNDFYCDCKNGWK----G 686
Query: 189 ANCRDVD-ECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
C D +C+ T C + +++C C G+E G C + N C + G
Sbjct: 687 KTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWE--GTTCNIARNSSCLPNPCHNGG 744
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC--QAPCRNYAGGYRCDCPVG 530
CV SF CVC G+ EG C C C + YRC+C G
Sbjct: 745 TCVVNGESFTCVCKEGW----EGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPG 798
Score = 62.1 bits (144), Expect = 1e-09
Identities = 49/178 (27%), Positives = 76/178 (42%), Gaps = 7/178 (3%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRD-ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
+ F C C G++ G+ RD +C C++ ++ C+C G+E G
Sbjct: 673 VNDFYCDCKNGWK--GKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWE----GTT 726
Query: 195 CRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSPGR 365
C + C C S+ C C++G+E G C + N+C C + G
Sbjct: 727 CNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWE--GPICAQNTNDCSPHP-CYNSGT 783
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
CV+ +RC C G+ G C ++ +EC Q+ C A C + GYRC CP G
Sbjct: 784 CVDGDNWYRCECAPGFA----GPDCRININEC-QSSPCAFGATCVDEINGYRCVCPPG 836
Score = 61.3 bits (142), Expect = 2e-09
Identities = 43/174 (24%), Positives = 70/174 (40%), Gaps = 4/174 (2%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 200
G F C C G+ D C P C + SY C+C G+E GA C
Sbjct: 598 GKFTCDCNKGFTGTYCHENIND-CESNPCRNGGTCIDGVNSYKCICSDGWE----GAYCE 652
Query: 201 -DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNL 377
++++C ++ C + + C C++G+ +G C + +E C + G C +
Sbjct: 653 TNINDCSQNPCHNGGTCRDLVNDFYCDCKNGW--KGKTCHSRDSQCDEATCNNGGTCYDE 710
Query: 378 LGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
+F+C+CP G+ EG C + R+ C C + C C G
Sbjct: 711 GDAFKCMCPGGW----EGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEG 760
Score = 52.8 bits (121), Expect = 8e-07
Identities = 44/155 (28%), Positives = 63/155 (40%), Gaps = 8/155 (5%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-RDVDECERDTHT-CQQ--ICS 251
D+C P +C+ + CLC T + G C +D++ C TH C CS
Sbjct: 250 DKCIPHPGCVHGICNEP---WQCLCETNW----GGQLCDKDLNYC--GTHQPCLNGGTCS 300
Query: 252 NT-EGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAE 428
NT Y+CSC +GY G C C + G C F C C G+
Sbjct: 301 NTGPDKYQCSCPEGYS--GPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGW----T 354
Query: 429 GARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCP 524
G C + D+C+ C C++ G++C CP
Sbjct: 355 GPTCSTNIDDCS-PNNCSHGGTCQDLVNGFKCVCP 388
>U73936-1|AAC52020.1| 1218|Homo sapiens Jagged 1 protein.
Length = 1218
Score = 82.6 bits (195), Expect = 8e-16
Identities = 57/175 (32%), Positives = 78/175 (44%), Gaps = 6/175 (3%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVR-GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
+ F+CVC P + G+ + +EC +P + C N SY C C G+ N
Sbjct: 393 VNGFKCVCPPQW--TGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDIN 450
Query: 195 CRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSPGRC 368
D + +C+ D C + Y C C GY GD C DI+EC C + G C
Sbjct: 451 INDCLGQCQNDAS-----CRDLVNGYRCICPPGYA--GDHCERDIDEC-ASNPCLNGGHC 502
Query: 369 VNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCP 524
N + F+C+CP G+ G C +D D C + CQ A C N A Y C CP
Sbjct: 503 QNEINRFQCLCPTGF----SGNLCQLDIDYC-EPNPCQNGAQCYNRASDYFCKCP 552
Score = 77.8 bits (183), Expect = 2e-14
Identities = 51/172 (29%), Positives = 73/172 (42%), Gaps = 4/172 (2%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-D 203
F C C PG+ D+C+ C + + C+C + G C+ D
Sbjct: 358 FECECSPGWTGPTCSTN-IDDCSPNNCSHGGTCQDLVNGFKCVCPPQWT----GKTCQLD 412
Query: 204 VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNLL 380
+ECE + C N SY C C G+ G C ++IN+C G C + C +L+
Sbjct: 413 ANECEAKPCVNAKSCKNLIASYYCDCLPGW--MGQNCDININDCL--GQCQNDASCRDLV 468
Query: 381 GSFRCVCPRGYRLDAEGARCV-DRDECAQTGRCQ-APCRNYAGGYRCDCPVG 530
+RC+CP GY G C D DECA C+N ++C CP G
Sbjct: 469 NGYRCICPPGY----AGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTG 516
Score = 67.3 bits (157), Expect = 3e-11
Identities = 48/172 (27%), Positives = 66/172 (38%), Gaps = 1/172 (0%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
+ +RC+C PGY R DECA P C N + CLC TG+ G C
Sbjct: 468 VNGYRCICPPGYA-GDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFS----GNLC 522
Query: 198 R-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVN 374
+ D+D CE + C N Y C C + YE G C + + C C
Sbjct: 523 QLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYE--GKNCSHLKDHCRTTPCEVIDSCTV 580
Query: 375 LLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
+ S EG R + + C G+C++ G + CDC G
Sbjct: 581 AMAS---------NDTPEGVRYISSNVCGPHGKCKS---QSGGKFTCDCNKG 620
Score = 65.7 bits (153), Expect = 1e-10
Identities = 39/142 (27%), Positives = 63/142 (44%), Gaps = 3/142 (2%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-R 200
+F+C+C G+ + C P C S+ C+C+ G+E G C +
Sbjct: 726 AFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWE----GPICAQ 781
Query: 201 DVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVN 374
+ ++C H C C + + Y C C G+ D ++INEC + C CV+
Sbjct: 782 NTNDC--SPHPCYNSGTCVDGDNWYRCECAPGF-AGPDCRININEC-QSSPCAFGATCVD 837
Query: 375 LLGSFRCVCPRGYRLDAEGARC 440
+ +RCVCP G+ GA+C
Sbjct: 838 EINGYRCVCPPGH----SGAKC 855
Score = 62.9 bits (146), Expect = 7e-10
Identities = 45/178 (25%), Positives = 70/178 (39%), Gaps = 4/178 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ + S++C+C G+ A D C+ P C + + C C+ G++ G
Sbjct: 645 IDGVNSYKCICSDGWEGAYCETNIND-CSQNPCHNGGTCRDLVNDFYCDCKNGWK----G 699
Query: 189 ANCRDVD-ECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
C D +C+ T C + +++C C G+E G C + N C + G
Sbjct: 700 KTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWE--GTTCNIARNSSCLPNPCHNGG 757
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC--QAPCRNYAGGYRCDCPVG 530
CV SF CVC G+ EG C C C + YRC+C G
Sbjct: 758 TCVVNGESFTCVCKEGW----EGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPG 811
Score = 62.1 bits (144), Expect = 1e-09
Identities = 49/178 (27%), Positives = 76/178 (42%), Gaps = 7/178 (3%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRD-ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
+ F C C G++ G+ RD +C C++ ++ C+C G+E G
Sbjct: 686 VNDFYCDCKNGWK--GKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWE----GTT 739
Query: 195 CRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSPGR 365
C + C C S+ C C++G+E G C + N+C C + G
Sbjct: 740 CNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWE--GPICAQNTNDCSPHP-CYNSGT 796
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
CV+ +RC C G+ G C ++ +EC Q+ C A C + GYRC CP G
Sbjct: 797 CVDGDNWYRCECAPGFA----GPDCRININEC-QSSPCAFGATCVDEINGYRCVCPPG 849
Score = 61.3 bits (142), Expect = 2e-09
Identities = 43/174 (24%), Positives = 70/174 (40%), Gaps = 4/174 (2%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 200
G F C C G+ D C P C + SY C+C G+E GA C
Sbjct: 611 GKFTCDCNKGFTGTYCHENIND-CESNPCRNGGTCIDGVNSYKCICSDGWE----GAYCE 665
Query: 201 -DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNL 377
++++C ++ C + + C C++G+ +G C + +E C + G C +
Sbjct: 666 TNINDCSQNPCHNGGTCRDLVNDFYCDCKNGW--KGKTCHSRDSQCDEATCNNGGTCYDE 723
Query: 378 LGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
+F+C+CP G+ EG C + R+ C C + C C G
Sbjct: 724 GDAFKCMCPGGW----EGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEG 773
Score = 52.8 bits (121), Expect = 8e-07
Identities = 44/155 (28%), Positives = 63/155 (40%), Gaps = 8/155 (5%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-RDVDECERDTHT-CQQ--ICS 251
D+C P +C+ + CLC T + G C +D++ C TH C CS
Sbjct: 263 DKCIPHPGCVHGICNEP---WQCLCETNW----GGQLCDKDLNYC--GTHQPCLNGGTCS 313
Query: 252 NT-EGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAE 428
NT Y+CSC +GY G C C + G C F C C G+
Sbjct: 314 NTGPDKYQCSCPEGYS--GPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGW----T 367
Query: 429 GARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCP 524
G C + D+C+ C C++ G++C CP
Sbjct: 368 GPTCSTNIDDCS-PNNCSHGGTCQDLVNGFKCVCP 401
>U61276-1|AAB39007.1| 1218|Homo sapiens transmembrane protein Jagged
1 protein.
Length = 1218
Score = 82.6 bits (195), Expect = 8e-16
Identities = 57/175 (32%), Positives = 78/175 (44%), Gaps = 6/175 (3%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVR-GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
+ F+CVC P + G+ + +EC +P + C N SY C C G+ N
Sbjct: 393 VNGFKCVCPPQW--TGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDIN 450
Query: 195 CRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSPGRC 368
D + +C+ D C + Y C C GY GD C DI+EC C + G C
Sbjct: 451 INDCLGQCQNDAS-----CRDLVNGYRCICPPGYA--GDHCERDIDEC-ASNPCLNGGHC 502
Query: 369 VNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCP 524
N + F+C+CP G+ G C +D D C + CQ A C N A Y C CP
Sbjct: 503 QNEINRFQCLCPTGF----SGNLCQLDIDYC-EPNPCQNGAQCYNRASDYFCKCP 552
Score = 77.8 bits (183), Expect = 2e-14
Identities = 51/172 (29%), Positives = 73/172 (42%), Gaps = 4/172 (2%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-D 203
F C C PG+ D+C+ C + + C+C + G C+ D
Sbjct: 358 FECECSPGWTGPTCSTN-IDDCSPNNCSHGGTCQDLVNGFKCVCPPQWT----GKTCQLD 412
Query: 204 VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNLL 380
+ECE + C N SY C C G+ G C ++IN+C G C + C +L+
Sbjct: 413 ANECEAKPCVNAKSCKNLIASYYCDCLPGW--MGQNCDININDCL--GQCQNDASCRDLV 468
Query: 381 GSFRCVCPRGYRLDAEGARCV-DRDECAQTGRCQ-APCRNYAGGYRCDCPVG 530
+RC+CP GY G C D DECA C+N ++C CP G
Sbjct: 469 NGYRCICPPGY----AGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTG 516
Score = 67.3 bits (157), Expect = 3e-11
Identities = 48/172 (27%), Positives = 66/172 (38%), Gaps = 1/172 (0%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
+ +RC+C PGY R DECA P C N + CLC TG+ G C
Sbjct: 468 VNGYRCICPPGYA-GDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFS----GNLC 522
Query: 198 R-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVN 374
+ D+D CE + C N Y C C + YE G C + + C C
Sbjct: 523 QLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYE--GKNCSHLKDHCRTTPCEVIDSCTV 580
Query: 375 LLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
+ S EG R + + C G+C++ G + CDC G
Sbjct: 581 AMAS---------NDTPEGVRYISSNVCGPHGKCKS---QSGGKFTCDCNKG 620
Score = 65.7 bits (153), Expect = 1e-10
Identities = 39/142 (27%), Positives = 63/142 (44%), Gaps = 3/142 (2%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-R 200
+F+C+C G+ + C P C S+ C+C+ G+E G C +
Sbjct: 726 AFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWE----GPICAQ 781
Query: 201 DVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVN 374
+ ++C H C C + + Y C C G+ D ++INEC + C CV+
Sbjct: 782 NTNDC--SPHPCYNSGTCVDGDNWYRCECAPGF-AGPDCRININEC-QSSPCAFGATCVD 837
Query: 375 LLGSFRCVCPRGYRLDAEGARC 440
+ +RCVCP G+ GA+C
Sbjct: 838 EINGYRCVCPPGH----SGAKC 855
Score = 62.9 bits (146), Expect = 7e-10
Identities = 45/178 (25%), Positives = 70/178 (39%), Gaps = 4/178 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ + S++C+C G+ A D C+ P C + + C C+ G++ G
Sbjct: 645 IDGVNSYKCICSDGWEGAYCETNIND-CSQNPCHNGGTCRDLVNDFYCDCKNGWK----G 699
Query: 189 ANCRDVD-ECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
C D +C+ T C + +++C C G+E G C + N C + G
Sbjct: 700 KTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWE--GTTCNIARNSSCLPNPCHNGG 757
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC--QAPCRNYAGGYRCDCPVG 530
CV SF CVC G+ EG C C C + YRC+C G
Sbjct: 758 TCVVNGESFTCVCKEGW----EGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPG 811
Score = 62.1 bits (144), Expect = 1e-09
Identities = 49/178 (27%), Positives = 76/178 (42%), Gaps = 7/178 (3%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRD-ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
+ F C C G++ G+ RD +C C++ ++ C+C G+E G
Sbjct: 686 VNDFYCDCKNGWK--GKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWE----GTT 739
Query: 195 CRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSPGR 365
C + C C S+ C C++G+E G C + N+C C + G
Sbjct: 740 CNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWE--GPICAQNTNDCSPHP-CYNSGT 796
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
CV+ +RC C G+ G C ++ +EC Q+ C A C + GYRC CP G
Sbjct: 797 CVDGDNWYRCECAPGFA----GPDCRININEC-QSSPCAFGATCVDEINGYRCVCPPG 849
Score = 61.3 bits (142), Expect = 2e-09
Identities = 43/174 (24%), Positives = 70/174 (40%), Gaps = 4/174 (2%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 200
G F C C G+ D C P C + SY C+C G+E GA C
Sbjct: 611 GKFTCDCNKGFTGTYCHENIND-CESNPCRNGGTCIDGVNSYKCICSDGWE----GAYCE 665
Query: 201 -DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNL 377
++++C ++ C + + C C++G+ +G C + +E C + G C +
Sbjct: 666 TNINDCSQNPCHNGGTCRDLVNDFYCDCKNGW--KGKTCHSRDSQCDEATCNNGGTCYDE 723
Query: 378 LGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
+F+C+CP G+ EG C + R+ C C + C C G
Sbjct: 724 GDAFKCMCPGGW----EGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEG 773
Score = 52.8 bits (121), Expect = 8e-07
Identities = 44/155 (28%), Positives = 63/155 (40%), Gaps = 8/155 (5%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-RDVDECERDTHT-CQQ--ICS 251
D+C P +C+ + CLC T + G C +D++ C TH C CS
Sbjct: 263 DKCIPHPGCVHGICNEP---WQCLCETNW----GGQLCDKDLNYC--GTHQPCLNGGTCS 313
Query: 252 NT-EGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAE 428
NT Y+CSC +GY G C C + G C F C C G+
Sbjct: 314 NTGPDKYQCSCPEGYS--GPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGW----T 367
Query: 429 GARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCP 524
G C + D+C+ C C++ G++C CP
Sbjct: 368 GPTCSTNIDDCS-PNNCSHGGTCQDLVNGFKCVCP 401
>BC126207-1|AAI26208.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 82.6 bits (195), Expect = 8e-16
Identities = 57/175 (32%), Positives = 78/175 (44%), Gaps = 6/175 (3%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVR-GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
+ F+CVC P + G+ + +EC +P + C N SY C C G+ N
Sbjct: 393 VNGFKCVCPPQW--TGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDIN 450
Query: 195 CRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSPGRC 368
D + +C+ D C + Y C C GY GD C DI+EC C + G C
Sbjct: 451 INDCLGQCQNDAS-----CRDLVNGYRCICPPGYA--GDHCERDIDEC-ASNPCLNGGHC 502
Query: 369 VNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCP 524
N + F+C+CP G+ G C +D D C + CQ A C N A Y C CP
Sbjct: 503 QNEINRFQCLCPTGF----SGNLCQLDIDYC-EPNPCQNGAQCYNRASDYFCKCP 552
Score = 77.8 bits (183), Expect = 2e-14
Identities = 51/172 (29%), Positives = 73/172 (42%), Gaps = 4/172 (2%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-D 203
F C C PG+ D+C+ C + + C+C + G C+ D
Sbjct: 358 FECECSPGWTGPTCSTN-IDDCSPNNCSHGGTCQDLVNGFKCVCPPQWT----GKTCQLD 412
Query: 204 VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNLL 380
+ECE + C N SY C C G+ G C ++IN+C G C + C +L+
Sbjct: 413 ANECEAKPCVNAKSCKNLIASYYCDCLPGW--MGQNCDININDCL--GQCQNDASCRDLV 468
Query: 381 GSFRCVCPRGYRLDAEGARCV-DRDECAQTGRCQ-APCRNYAGGYRCDCPVG 530
+RC+CP GY G C D DECA C+N ++C CP G
Sbjct: 469 NGYRCICPPGY----AGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTG 516
Score = 67.3 bits (157), Expect = 3e-11
Identities = 48/172 (27%), Positives = 66/172 (38%), Gaps = 1/172 (0%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
+ +RC+C PGY R DECA P C N + CLC TG+ G C
Sbjct: 468 VNGYRCICPPGYA-GDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFS----GNLC 522
Query: 198 R-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVN 374
+ D+D CE + C N Y C C + YE G C + + C C
Sbjct: 523 QLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYE--GKNCSHLKDHCRTTPCEVIDSCTV 580
Query: 375 LLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
+ S EG R + + C G+C++ G + CDC G
Sbjct: 581 AMAS---------NDTPEGVRYISSNVCGPHGKCKS---QSGGKFTCDCNKG 620
Score = 65.7 bits (153), Expect = 1e-10
Identities = 39/142 (27%), Positives = 63/142 (44%), Gaps = 3/142 (2%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-R 200
+F+C+C G+ + C P C S+ C+C+ G+E G C +
Sbjct: 726 AFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWE----GPICAQ 781
Query: 201 DVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVN 374
+ ++C H C C + + Y C C G+ D ++INEC + C CV+
Sbjct: 782 NTNDC--SPHPCYNSGTCVDGDNWYRCECAPGF-AGPDCRININEC-QSSPCAFGATCVD 837
Query: 375 LLGSFRCVCPRGYRLDAEGARC 440
+ +RCVCP G+ GA+C
Sbjct: 838 EINGYRCVCPPGH----SGAKC 855
Score = 62.9 bits (146), Expect = 7e-10
Identities = 45/178 (25%), Positives = 70/178 (39%), Gaps = 4/178 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ + S++C+C G+ A D C+ P C + + C C+ G++ G
Sbjct: 645 IDGVNSYKCICSDGWEGAYCETNIND-CSQNPCHNGGTCRDLVNDFYCDCKNGWK----G 699
Query: 189 ANCRDVD-ECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
C D +C+ T C + +++C C G+E G C + N C + G
Sbjct: 700 KTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWE--GTTCNIARNSSCLPNPCHNGG 757
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC--QAPCRNYAGGYRCDCPVG 530
CV SF CVC G+ EG C C C + YRC+C G
Sbjct: 758 TCVVNGESFTCVCKEGW----EGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPG 811
Score = 62.1 bits (144), Expect = 1e-09
Identities = 49/178 (27%), Positives = 76/178 (42%), Gaps = 7/178 (3%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRD-ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
+ F C C G++ G+ RD +C C++ ++ C+C G+E G
Sbjct: 686 VNDFYCDCKNGWK--GKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWE----GTT 739
Query: 195 CRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSPGR 365
C + C C S+ C C++G+E G C + N+C C + G
Sbjct: 740 CNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWE--GPICAQNTNDCSPHP-CYNSGT 796
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
CV+ +RC C G+ G C ++ +EC Q+ C A C + GYRC CP G
Sbjct: 797 CVDGDNWYRCECAPGFA----GPDCRININEC-QSSPCAFGATCVDEINGYRCVCPPG 849
Score = 61.3 bits (142), Expect = 2e-09
Identities = 43/174 (24%), Positives = 70/174 (40%), Gaps = 4/174 (2%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 200
G F C C G+ D C P C + SY C+C G+E GA C
Sbjct: 611 GKFTCDCNKGFTGTYCHENIND-CESNPCRNGGTCIDGVNSYKCICSDGWE----GAYCE 665
Query: 201 -DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNL 377
++++C ++ C + + C C++G+ +G C + +E C + G C +
Sbjct: 666 TNINDCSQNPCHNGGTCRDLVNDFYCDCKNGW--KGKTCHSRDSQCDEATCNNGGTCYDE 723
Query: 378 LGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
+F+C+CP G+ EG C + R+ C C + C C G
Sbjct: 724 GDAFKCMCPGGW----EGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEG 773
Score = 52.8 bits (121), Expect = 8e-07
Identities = 44/155 (28%), Positives = 63/155 (40%), Gaps = 8/155 (5%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-RDVDECERDTHT-CQQ--ICS 251
D+C P +C+ + CLC T + G C +D++ C TH C CS
Sbjct: 263 DKCIPHPGCVHGICNEP---WQCLCETNW----GGQLCDKDLNYC--GTHQPCLNGGTCS 313
Query: 252 NT-EGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAE 428
NT Y+CSC +GY G C C + G C F C C G+
Sbjct: 314 NTGPDKYQCSCPEGYS--GPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGW----T 367
Query: 429 GARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCP 524
G C + D+C+ C C++ G++C CP
Sbjct: 368 GPTCSTNIDDCS-PNNCSHGGTCQDLVNGFKCVCP 401
>BC126205-1|AAI26206.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 82.6 bits (195), Expect = 8e-16
Identities = 57/175 (32%), Positives = 78/175 (44%), Gaps = 6/175 (3%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVR-GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
+ F+CVC P + G+ + +EC +P + C N SY C C G+ N
Sbjct: 393 VNGFKCVCPPQW--TGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDIN 450
Query: 195 CRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSPGRC 368
D + +C+ D C + Y C C GY GD C DI+EC C + G C
Sbjct: 451 INDCLGQCQNDAS-----CRDLVNGYRCICPPGYA--GDHCERDIDEC-ASNPCLNGGHC 502
Query: 369 VNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCP 524
N + F+C+CP G+ G C +D D C + CQ A C N A Y C CP
Sbjct: 503 QNEINRFQCLCPTGF----SGNLCQLDIDYC-EPNPCQNGAQCYNRASDYFCKCP 552
Score = 77.8 bits (183), Expect = 2e-14
Identities = 51/172 (29%), Positives = 73/172 (42%), Gaps = 4/172 (2%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-D 203
F C C PG+ D+C+ C + + C+C + G C+ D
Sbjct: 358 FECECSPGWTGPTCSTN-IDDCSPNNCSHGGTCQDLVNGFKCVCPPQWT----GKTCQLD 412
Query: 204 VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNLL 380
+ECE + C N SY C C G+ G C ++IN+C G C + C +L+
Sbjct: 413 ANECEAKPCVNAKSCKNLIASYYCDCLPGW--MGQNCDININDCL--GQCQNDASCRDLV 468
Query: 381 GSFRCVCPRGYRLDAEGARCV-DRDECAQTGRCQ-APCRNYAGGYRCDCPVG 530
+RC+CP GY G C D DECA C+N ++C CP G
Sbjct: 469 NGYRCICPPGY----AGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTG 516
Score = 67.3 bits (157), Expect = 3e-11
Identities = 48/172 (27%), Positives = 66/172 (38%), Gaps = 1/172 (0%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
+ +RC+C PGY R DECA P C N + CLC TG+ G C
Sbjct: 468 VNGYRCICPPGYA-GDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFS----GNLC 522
Query: 198 R-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVN 374
+ D+D CE + C N Y C C + YE G C + + C C
Sbjct: 523 QLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYE--GKNCSHLKDHCRTTPCEVIDSCTV 580
Query: 375 LLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
+ S EG R + + C G+C++ G + CDC G
Sbjct: 581 AMAS---------NDTPEGVRYISSNVCGPHGKCKS---QSGGKFTCDCNKG 620
Score = 65.7 bits (153), Expect = 1e-10
Identities = 39/142 (27%), Positives = 63/142 (44%), Gaps = 3/142 (2%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-R 200
+F+C+C G+ + C P C S+ C+C+ G+E G C +
Sbjct: 726 AFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWE----GPICAQ 781
Query: 201 DVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVN 374
+ ++C H C C + + Y C C G+ D ++INEC + C CV+
Sbjct: 782 NTNDC--SPHPCYNSGTCVDGDNWYRCECAPGF-AGPDCRININEC-QSSPCAFGATCVD 837
Query: 375 LLGSFRCVCPRGYRLDAEGARC 440
+ +RCVCP G+ GA+C
Sbjct: 838 EINGYRCVCPPGH----SGAKC 855
Score = 62.9 bits (146), Expect = 7e-10
Identities = 45/178 (25%), Positives = 70/178 (39%), Gaps = 4/178 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ + S++C+C G+ A D C+ P C + + C C+ G++ G
Sbjct: 645 IDGVNSYKCICSDGWEGAYCETNIND-CSQNPCHNGGTCRDLVNDFYCDCKNGWK----G 699
Query: 189 ANCRDVD-ECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
C D +C+ T C + +++C C G+E G C + N C + G
Sbjct: 700 KTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWE--GTTCNIARNSSCLPNPCHNGG 757
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC--QAPCRNYAGGYRCDCPVG 530
CV SF CVC G+ EG C C C + YRC+C G
Sbjct: 758 TCVVNGESFTCVCKEGW----EGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPG 811
Score = 62.1 bits (144), Expect = 1e-09
Identities = 49/178 (27%), Positives = 76/178 (42%), Gaps = 7/178 (3%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRD-ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
+ F C C G++ G+ RD +C C++ ++ C+C G+E G
Sbjct: 686 VNDFYCDCKNGWK--GKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWE----GTT 739
Query: 195 CRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSPGR 365
C + C C S+ C C++G+E G C + N+C C + G
Sbjct: 740 CNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWE--GPICAQNTNDCSPHP-CYNSGT 796
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
CV+ +RC C G+ G C ++ +EC Q+ C A C + GYRC CP G
Sbjct: 797 CVDGDNWYRCECAPGFA----GPDCRININEC-QSSPCAFGATCVDEINGYRCVCPPG 849
Score = 61.3 bits (142), Expect = 2e-09
Identities = 43/174 (24%), Positives = 70/174 (40%), Gaps = 4/174 (2%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 200
G F C C G+ D C P C + SY C+C G+E GA C
Sbjct: 611 GKFTCDCNKGFTGTYCHENIND-CESNPCRNGGTCIDGVNSYKCICSDGWE----GAYCE 665
Query: 201 -DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNL 377
++++C ++ C + + C C++G+ +G C + +E C + G C +
Sbjct: 666 TNINDCSQNPCHNGGTCRDLVNDFYCDCKNGW--KGKTCHSRDSQCDEATCNNGGTCYDE 723
Query: 378 LGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
+F+C+CP G+ EG C + R+ C C + C C G
Sbjct: 724 GDAFKCMCPGGW----EGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEG 773
Score = 52.8 bits (121), Expect = 8e-07
Identities = 44/155 (28%), Positives = 63/155 (40%), Gaps = 8/155 (5%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-RDVDECERDTHT-CQQ--ICS 251
D+C P +C+ + CLC T + G C +D++ C TH C CS
Sbjct: 263 DKCIPHPGCVHGICNEP---WQCLCETNW----GGQLCDKDLNYC--GTHQPCLNGGTCS 313
Query: 252 NT-EGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAE 428
NT Y+CSC +GY G C C + G C F C C G+
Sbjct: 314 NTGPDKYQCSCPEGYS--GPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGW----T 367
Query: 429 GARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCP 524
G C + D+C+ C C++ G++C CP
Sbjct: 368 GPTCSTNIDDCS-PNNCSHGGTCQDLVNGFKCVCP 401
>BC098393-1|AAH98393.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 82.6 bits (195), Expect = 8e-16
Identities = 57/175 (32%), Positives = 78/175 (44%), Gaps = 6/175 (3%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVR-GRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
+ F+CVC P + G+ + +EC +P + C N SY C C G+ N
Sbjct: 393 VNGFKCVCPPQW--TGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDIN 450
Query: 195 CRD-VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSPGRC 368
D + +C+ D C + Y C C GY GD C DI+EC C + G C
Sbjct: 451 INDCLGQCQNDAS-----CRDLVNGYRCICPPGYA--GDHCERDIDEC-ASNPCLNGGHC 502
Query: 369 VNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCP 524
N + F+C+CP G+ G C +D D C + CQ A C N A Y C CP
Sbjct: 503 QNEINRFQCLCPTGF----SGNLCQLDIDYC-EPNPCQNGAQCYNRASDYFCKCP 552
Score = 77.8 bits (183), Expect = 2e-14
Identities = 51/172 (29%), Positives = 73/172 (42%), Gaps = 4/172 (2%)
Frame = +3
Query: 27 FRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR-D 203
F C C PG+ D+C+ C + + C+C + G C+ D
Sbjct: 358 FECECSPGWTGPTCSTN-IDDCSPNNCSHGGTCQDLVNGFKCVCPPQWT----GKTCQLD 412
Query: 204 VDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPGRCVNLL 380
+ECE + C N SY C C G+ G C ++IN+C G C + C +L+
Sbjct: 413 ANECEAKPCVNAKSCKNLIASYYCDCLPGW--MGQNCDININDCL--GQCQNDASCRDLV 468
Query: 381 GSFRCVCPRGYRLDAEGARCV-DRDECAQTGRCQ-APCRNYAGGYRCDCPVG 530
+RC+CP GY G C D DECA C+N ++C CP G
Sbjct: 469 NGYRCICPPGY----AGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTG 516
Score = 67.3 bits (157), Expect = 3e-11
Identities = 48/172 (27%), Positives = 66/172 (38%), Gaps = 1/172 (0%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC 197
+ +RC+C PGY R DECA P C N + CLC TG+ G C
Sbjct: 468 VNGYRCICPPGYA-GDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFS----GNLC 522
Query: 198 R-DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVN 374
+ D+D CE + C N Y C C + YE G C + + C C
Sbjct: 523 QLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYE--GKNCSHLKDHCRTTPCEVIDSCTV 580
Query: 375 LLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRCQAPCRNYAGGYRCDCPVG 530
+ S EG R + + C G+C++ G + CDC G
Sbjct: 581 AMAS---------NDTPEGVRYISSNVCGPHGKCKS---QSGGKFTCDCNKG 620
Score = 65.7 bits (153), Expect = 1e-10
Identities = 39/142 (27%), Positives = 63/142 (44%), Gaps = 3/142 (2%)
Frame = +3
Query: 24 SFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-R 200
+F+C+C G+ + C P C S+ C+C+ G+E G C +
Sbjct: 726 AFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWE----GPICAQ 781
Query: 201 DVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVN 374
+ ++C H C C + + Y C C G+ D ++INEC + C CV+
Sbjct: 782 NTNDC--SPHPCYNSGTCVDGDNWYRCECAPGF-AGPDCRININEC-QSSPCAFGATCVD 837
Query: 375 LLGSFRCVCPRGYRLDAEGARC 440
+ +RCVCP G+ GA+C
Sbjct: 838 EINGYRCVCPPGH----SGAKC 855
Score = 62.9 bits (146), Expect = 7e-10
Identities = 45/178 (25%), Positives = 70/178 (39%), Gaps = 4/178 (2%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDG 188
++ + S++C+C G+ A D C+ P C + + C C+ G++ G
Sbjct: 645 IDGVNSYKCICSDGWEGAYCETNIND-CSQNPCHNGGTCRDLVNDFYCDCKNGWK----G 699
Query: 189 ANCRDVD-ECERDTHTCQQICSNTEGSYECSCEDGYEKRGDAC-VDINECHEEGVCPSPG 362
C D +C+ T C + +++C C G+E G C + N C + G
Sbjct: 700 KTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWE--GTTCNIARNSSCLPNPCHNGG 757
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDRDECAQTGRC--QAPCRNYAGGYRCDCPVG 530
CV SF CVC G+ EG C C C + YRC+C G
Sbjct: 758 TCVVNGESFTCVCKEGW----EGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPG 811
Score = 62.1 bits (144), Expect = 1e-09
Identities = 49/178 (27%), Positives = 76/178 (42%), Gaps = 7/178 (3%)
Frame = +3
Query: 18 IGSFRCVCGPGYRPAGRGVRGRD-ECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGAN 194
+ F C C G++ G+ RD +C C++ ++ C+C G+E G
Sbjct: 686 VNDFYCDCKNGWK--GKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWE----GTT 739
Query: 195 CRDVDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDACV-DINECHEEGVCPSPGR 365
C + C C S+ C C++G+E G C + N+C C + G
Sbjct: 740 CNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWE--GPICAQNTNDCSPHP-CYNSGT 796
Query: 366 CVNLLGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
CV+ +RC C G+ G C ++ +EC Q+ C A C + GYRC CP G
Sbjct: 797 CVDGDNWYRCECAPGFA----GPDCRININEC-QSSPCAFGATCVDEINGYRCVCPPG 849
Score = 61.3 bits (142), Expect = 2e-09
Identities = 43/174 (24%), Positives = 70/174 (40%), Gaps = 4/174 (2%)
Frame = +3
Query: 21 GSFRCVCGPGYRPAGRGVRGRDECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANCR 200
G F C C G+ D C P C + SY C+C G+E GA C
Sbjct: 611 GKFTCDCNKGFTGTYCHENIND-CESNPCRNGGTCIDGVNSYKCICSDGWE----GAYCE 665
Query: 201 -DVDECERDTHTCQQICSNTEGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNL 377
++++C ++ C + + C C++G+ +G C + +E C + G C +
Sbjct: 666 TNINDCSQNPCHNGGTCRDLVNDFYCDCKNGW--KGKTCHSRDSQCDEATCNNGGTCYDE 723
Query: 378 LGSFRCVCPRGYRLDAEGARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCPVG 530
+F+C+CP G+ EG C + R+ C C + C C G
Sbjct: 724 GDAFKCMCPGGW----EGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEG 773
Score = 52.8 bits (121), Expect = 8e-07
Identities = 44/155 (28%), Positives = 63/155 (40%), Gaps = 8/155 (5%)
Frame = +3
Query: 84 DECAVRPPPCDQLCHNTDGSYDCLCRTGYELDEDGANC-RDVDECERDTHT-CQQ--ICS 251
D+C P +C+ + CLC T + G C +D++ C TH C CS
Sbjct: 263 DKCIPHPGCVHGICNEP---WQCLCETNW----GGQLCDKDLNYC--GTHQPCLNGGTCS 313
Query: 252 NT-EGSYECSCEDGYEKRGDACVDINECHEEGVCPSPGRCVNLLGSFRCVCPRGYRLDAE 428
NT Y+CSC +GY G C C + G C F C C G+
Sbjct: 314 NTGPDKYQCSCPEGYS--GPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGW----T 367
Query: 429 GARC-VDRDECAQTGRCQ--APCRNYAGGYRCDCP 524
G C + D+C+ C C++ G++C CP
Sbjct: 368 GPTCSTNIDDCS-PNNCSHGGTCQDLVNGFKCVCP 401
>AL731551-1|CAI40246.1| 3623|Homo sapiens cubilin (intrinsic
factor-cobalamin receptor) protein.
Length = 3623
Score = 82.6 bits (195), Expect = 8e-16
Identities = 65/193 (33%), Positives = 82/193 (42%), Gaps = 19/193 (9%)
Frame = +3
Query: 9 VNTIGSFRCVCGPG-YRP--AGR--GVRGRDECAVRPPPCDQLCHNTDGS--YDCLCRTG 167
VNT+GS+ C C P Y P A + G C+ L G Y C+C G
Sbjct: 191 VNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVCDAG 250
Query: 168 YELDEDGANCR-DVDECERDTHTCQQI--CSNTEGSYEC-SCEDGYEKRGDACVDINECH 335
+ + C D DEC C + C NT+GS+ C +C G++ G C DINEC
Sbjct: 251 WMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECE 310
Query: 336 -EEGVC--PSPGRCVNLLGSFRC-VCPRGYRLDAEGARCVDRDECA-QTGRC--QAPCRN 494
G C P CVN GS C CP GY+ +G C D C+ G C A C +
Sbjct: 311 INNGGCSVAPPVECVNTPGSSHCQACPPGYQ--GDGRVCTLTDICSVSNGGCHPDASCSS 368
Query: 495 YAGGY-RCDCPVG 530
G C C G
Sbjct: 369 TLGSLPLCTCLPG 381
Score = 66.1 bits (154), Expect = 8e-11
Identities = 51/140 (36%), Positives = 64/140 (45%), Gaps = 7/140 (5%)
Frame = +3
Query: 9 VNTIGSFRC-VCGPGYRPAGRGVRGRDECAVRPPPC--DQLCHNTDGSYD-CLCRTGYEL 176
VNT GS C C PGY+ GR D C+V C D C +T GS C C GY
Sbjct: 325 VNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTG 384
Query: 177 DEDGAN-CRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGV 347
+ G N C + +H C C +T Y C C+ G+ G C + INEC
Sbjct: 385 NGYGPNGCVQLSNICL-SHPCLNGQCIDTVSGYFCKCDSGWT--GVNCTENINECLSNP- 440
Query: 348 CPSPGRCVNLLGSFRCVCPR 407
C + G CV+ + SF C C R
Sbjct: 441 CLNGGTCVDGVDSFSCECTR 460
Score = 64.9 bits (151), Expect = 2e-10
Identities = 63/199 (31%), Positives = 83/199 (41%), Gaps = 25/199 (12%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAV---RPPPCDQ--LCHNTDGSYDCLCRTGYE 173
+N SF C+C P ++ +EC + P C C NT GSY C C
Sbjct: 148 LNLHDSFFCICPPQWKGPLCSA-DVNECEIYSGTPLSCQNGGTCVNTMGSYSCHCPP--- 203
Query: 174 LDEDGANCRD-VDECE-----RDTH-TCQQICSNTEG--SYECSCEDG--YEKRGDAC-V 317
+ G C D+CE R H C+ + G Y C C+ G + AC +
Sbjct: 204 -ETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVCDAGWMFSPNSPACTL 262
Query: 318 DINEC-HEEGVCPSPGRCVNLLGSFRC-VCPRGYRLDAEGARCVDRDEC-AQTGRCQ-AP 485
D +EC + G C + +C N GSF C CP G++ G C D +EC G C AP
Sbjct: 263 DRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQ--GNGYICEDINECEINNGGCSVAP 320
Query: 486 ---CRNYAGGYRCD-CPVG 530
C N G C CP G
Sbjct: 321 PVECVNTPGSSHCQACPPG 339
Score = 62.1 bits (144), Expect = 1e-09
Identities = 52/184 (28%), Positives = 74/184 (40%), Gaps = 14/184 (7%)
Frame = +3
Query: 12 NTIGSFRC-VCGPGYRPAGRGVRGRDECAVRPPPCDQL----CHNTDGSYDC-LCRTGYE 173
NT GSF C C G++ G +EC + C C NT GS C C GY+
Sbjct: 282 NTQGSFYCGACPTGWQGNGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQ 341
Query: 174 LDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYE-CSCEDGYEKRG---DACVDINECH 335
DG C D C C CS+T GS C+C GY G + CV ++
Sbjct: 342 --GDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNIC 399
Query: 336 EEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ-APCRNYAGGY 509
C + G+C++ + + C C G+ G C + +EC C + +
Sbjct: 400 LSHPCLN-GQCIDTVSGYFCKCDSGW----TGVNCTENINECLSNPCLNGGTCVDGVDSF 454
Query: 510 RCDC 521
C+C
Sbjct: 455 SCEC 458
Score = 50.4 bits (115), Expect = 4e-06
Identities = 41/132 (31%), Positives = 58/132 (43%), Gaps = 17/132 (12%)
Frame = +3
Query: 204 VDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC-VDINECH-EEGV---CPSPG 362
VD+ ++ CQ C N S+ C C + +G C D+NEC G C + G
Sbjct: 131 VDKKVCSSNPCQNGGTCLNLHDSFFCICPPQW--KGPLCSADVNECEIYSGTPLSCQNGG 188
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDR-DEC-------AQTGRCQAPCRNYAG--GYR 512
CVN +GS+ C CP + G +C + D+C G C+ R AG Y
Sbjct: 189 TCVNTMGSYSCHCPP----ETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYS 244
Query: 513 CDCPVGTVRSPS 548
C C G + SP+
Sbjct: 245 CVCDAGWMFSPN 256
>AL596445-1|CAH72450.1| 3623|Homo sapiens cubilin (intrinsic
factor-cobalamin receptor) protein.
Length = 3623
Score = 82.6 bits (195), Expect = 8e-16
Identities = 65/193 (33%), Positives = 82/193 (42%), Gaps = 19/193 (9%)
Frame = +3
Query: 9 VNTIGSFRCVCGPG-YRP--AGR--GVRGRDECAVRPPPCDQLCHNTDGS--YDCLCRTG 167
VNT+GS+ C C P Y P A + G C+ L G Y C+C G
Sbjct: 191 VNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVCDAG 250
Query: 168 YELDEDGANCR-DVDECERDTHTCQQI--CSNTEGSYEC-SCEDGYEKRGDACVDINECH 335
+ + C D DEC C + C NT+GS+ C +C G++ G C DINEC
Sbjct: 251 WMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECE 310
Query: 336 -EEGVC--PSPGRCVNLLGSFRC-VCPRGYRLDAEGARCVDRDECA-QTGRC--QAPCRN 494
G C P CVN GS C CP GY+ +G C D C+ G C A C +
Sbjct: 311 INNGGCSVAPPVECVNTPGSSHCQACPPGYQ--GDGRVCTLTDICSVSNGGCHPDASCSS 368
Query: 495 YAGGY-RCDCPVG 530
G C C G
Sbjct: 369 TLGSLPLCTCLPG 381
Score = 66.1 bits (154), Expect = 8e-11
Identities = 51/140 (36%), Positives = 64/140 (45%), Gaps = 7/140 (5%)
Frame = +3
Query: 9 VNTIGSFRC-VCGPGYRPAGRGVRGRDECAVRPPPC--DQLCHNTDGSYD-CLCRTGYEL 176
VNT GS C C PGY+ GR D C+V C D C +T GS C C GY
Sbjct: 325 VNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTG 384
Query: 177 DEDGAN-CRDVDECERDTHTCQQ-ICSNTEGSYECSCEDGYEKRGDACVD-INECHEEGV 347
+ G N C + +H C C +T Y C C+ G+ G C + INEC
Sbjct: 385 NGYGPNGCVQLSNICL-SHPCLNGQCIDTVSGYFCKCDSGWT--GVNCTENINECLSNP- 440
Query: 348 CPSPGRCVNLLGSFRCVCPR 407
C + G CV+ + SF C C R
Sbjct: 441 CLNGGTCVDGVDSFSCECTR 460
Score = 64.9 bits (151), Expect = 2e-10
Identities = 63/199 (31%), Positives = 83/199 (41%), Gaps = 25/199 (12%)
Frame = +3
Query: 9 VNTIGSFRCVCGPGYRPAGRGVRGRDECAV---RPPPCDQ--LCHNTDGSYDCLCRTGYE 173
+N SF C+C P ++ +EC + P C C NT GSY C C
Sbjct: 148 LNLHDSFFCICPPQWKGPLCSA-DVNECEIYSGTPLSCQNGGTCVNTMGSYSCHCPP--- 203
Query: 174 LDEDGANCRD-VDECE-----RDTH-TCQQICSNTEG--SYECSCEDG--YEKRGDAC-V 317
+ G C D+CE R H C+ + G Y C C+ G + AC +
Sbjct: 204 -ETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVCDAGWMFSPNSPACTL 262
Query: 318 DINEC-HEEGVCPSPGRCVNLLGSFRC-VCPRGYRLDAEGARCVDRDEC-AQTGRCQ-AP 485
D +EC + G C + +C N GSF C CP G++ G C D +EC G C AP
Sbjct: 263 DRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQ--GNGYICEDINECEINNGGCSVAP 320
Query: 486 ---CRNYAGGYRCD-CPVG 530
C N G C CP G
Sbjct: 321 PVECVNTPGSSHCQACPPG 339
Score = 62.1 bits (144), Expect = 1e-09
Identities = 52/184 (28%), Positives = 74/184 (40%), Gaps = 14/184 (7%)
Frame = +3
Query: 12 NTIGSFRC-VCGPGYRPAGRGVRGRDECAVRPPPCDQL----CHNTDGSYDC-LCRTGYE 173
NT GSF C C G++ G +EC + C C NT GS C C GY+
Sbjct: 282 NTQGSFYCGACPTGWQGNGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQ 341
Query: 174 LDEDGANCRDVDECERDTHTCQQ--ICSNTEGSYE-CSCEDGYEKRG---DACVDINECH 335
DG C D C C CS+T GS C+C GY G + CV ++
Sbjct: 342 --GDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNIC 399
Query: 336 EEGVCPSPGRCVNLLGSFRCVCPRGYRLDAEGARCVDR-DECAQTGRCQ-APCRNYAGGY 509
C + G+C++ + + C C G+ G C + +EC C + +
Sbjct: 400 LSHPCLN-GQCIDTVSGYFCKCDSGW----TGVNCTENINECLSNPCLNGGTCVDGVDSF 454
Query: 510 RCDC 521
C+C
Sbjct: 455 SCEC 458
Score = 50.4 bits (115), Expect = 4e-06
Identities = 41/132 (31%), Positives = 58/132 (43%), Gaps = 17/132 (12%)
Frame = +3
Query: 204 VDECERDTHTCQQ--ICSNTEGSYECSCEDGYEKRGDAC-VDINECH-EEGV---CPSPG 362
VD+ ++ CQ C N S+ C C + +G C D+NEC G C + G
Sbjct: 131 VDKKVCSSNPCQNGGTCLNLHDSFFCICPPQW--KGPLCSADVNECEIYSGTPLSCQNGG 188
Query: 363 RCVNLLGSFRCVCPRGYRLDAEGARCVDR-DEC-------AQTGRCQAPCRNYAG--GYR 512
CVN +GS+ C CP + G +C + D+C G C+ R AG Y
Sbjct: 189 TCVNTMGSYSCHCPP----ETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYS 244
Query: 513 CDCPVGTVRSPS 548
C C G + SP+
Sbjct: 245 CVCDAGWMFSPN 256
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 69,992,789
Number of Sequences: 237096
Number of extensions: 1649972
Number of successful extensions: 23728
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 6860
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 12946
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 5477474182
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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