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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= P5PG0651
         (595 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

CR533532-1|CAG38563.1|  275|Homo sapiens PROSC protein.               209   6e-54
BC012334-1|AAH12334.1|  275|Homo sapiens proline synthetase co-t...   209   6e-54
AB018566-1|BAA36842.1|  275|Homo sapiens Proline synthetase asso...   209   6e-54
M14642-1|AAA51745.1|  396|Homo sapiens APOA4 protein.                  33   1.0  
M13654-1|AAA51744.1|  396|Homo sapiens APOA4 protein.                  33   1.0  
BC067299-1|AAH67299.1|  490|Homo sapiens Mdm4, transformed 3T3 c...    32   1.8  
AY207458-1|AAO13494.1|  490|Homo sapiens Mdm4, transformed 3T3 c...    32   1.8  
AL512306-5|CAI14100.1|  490|Homo sapiens Mdm4, transformed 3T3 c...    32   1.8  
AL512306-3|CAI14098.1|  213|Homo sapiens Mdm4, transformed 3T3 c...    32   1.8  
AK223228-1|BAD96948.1|  490|Homo sapiens mouse double minute 4 h...    32   1.8  
AF007111-1|AAB62928.1|  490|Homo sapiens MDM2-like p53-binding p...    32   1.8  
AL590543-3|CAI10943.1|  722|Homo sapiens chromosome 6 open readi...    31   2.3  
AL359494-1|CAH71980.1|  722|Homo sapiens chromosome 6 open readi...    31   2.3  
BC127772-1|AAI27773.1|  863|Homo sapiens KIF5C protein protein.        31   4.1  
BC110287-1|AAI10288.1|  725|Homo sapiens KIF5C protein protein.        31   4.1  
AC108512-1|AAX82030.1|  684|Homo sapiens unknown protein.              31   4.1  
AB209191-1|BAD92428.1|  265|Homo sapiens Kinesin heavy chain iso...    31   4.1  
AB011103-1|BAA25457.2|  999|Homo sapiens KIAA0531 protein protein.     31   4.1  
AL121586-7|CAB89415.1| 2442|Homo sapiens centrosomal protein 250...    30   5.4  
AF049105-1|AAC07988.1| 2442|Homo sapiens centrosomal Nek2-associ...    30   5.4  
AF022655-1|AAC06349.1| 2442|Homo sapiens cep250 centrosome assoc...    30   5.4  
AB209115-1|BAD92352.1| 1065|Homo sapiens restin isoform a varian...    29   9.4  

>CR533532-1|CAG38563.1|  275|Homo sapiens PROSC protein.
          Length = 275

 Score =  209 bits (510), Expect = 6e-54
 Identities = 98/172 (56%), Positives = 125/172 (72%)
 Frame = +2

Query: 80  VDAKVDIMYGLKTVLSQIEIAVARRSKDLPQIAPRLVAVSKIKPVELIVEAYNAGQRHFG 259
           + A++ +   L+ V  +++ AVARR +DLP I PRLVAVSK KP ++++EAY  GQR FG
Sbjct: 7   MSAELGVGCALRAVNERVQQAVARRPRDLPAIQPRLVAVSKTKPADMVIEAYGHGQRTFG 66

Query: 260 ENYVNELSDKASDPLILEKCKDIKWHFIGHLQTNKINKLLGSPGLFMVETVDSEKLADNL 439
           ENYV EL +KAS+P IL  C +IKWHFIGHLQ   +NKL+  P LFM+ETVDS KLAD +
Sbjct: 67  ENYVQELLEKASNPKILSLCPEIKWHFIGHLQKQNVNKLMAVPNLFMLETVDSVKLADKV 126

Query: 440 NKQWLKYRKEKERLRVMVQVNTSGEQAKSGLEPLETTKAVEHILENCPNLDF 595
           N  W + +   ERL+VMVQ+NTSGE++K GL P ET   VEHI   CPNL+F
Sbjct: 127 NSSWQR-KGSPERLKVMVQINTSGEESKHGLPPSETIAIVEHINAKCPNLEF 177


>BC012334-1|AAH12334.1|  275|Homo sapiens proline synthetase
           co-transcribed homolog (bacterial) protein.
          Length = 275

 Score =  209 bits (510), Expect = 6e-54
 Identities = 98/172 (56%), Positives = 125/172 (72%)
 Frame = +2

Query: 80  VDAKVDIMYGLKTVLSQIEIAVARRSKDLPQIAPRLVAVSKIKPVELIVEAYNAGQRHFG 259
           + A++ +   L+ V  +++ AVARR +DLP I PRLVAVSK KP ++++EAY  GQR FG
Sbjct: 7   MSAELGVGCALRAVNERVQQAVARRPRDLPAIQPRLVAVSKTKPADMVIEAYGHGQRTFG 66

Query: 260 ENYVNELSDKASDPLILEKCKDIKWHFIGHLQTNKINKLLGSPGLFMVETVDSEKLADNL 439
           ENYV EL +KAS+P IL  C +IKWHFIGHLQ   +NKL+  P LFM+ETVDS KLAD +
Sbjct: 67  ENYVQELLEKASNPKILSLCPEIKWHFIGHLQKQNVNKLMAVPNLFMLETVDSVKLADKV 126

Query: 440 NKQWLKYRKEKERLRVMVQVNTSGEQAKSGLEPLETTKAVEHILENCPNLDF 595
           N  W + +   ERL+VMVQ+NTSGE++K GL P ET   VEHI   CPNL+F
Sbjct: 127 NSSWQR-KGSPERLKVMVQINTSGEESKHGLPPSETIAIVEHINAKCPNLEF 177


>AB018566-1|BAA36842.1|  275|Homo sapiens Proline synthetase
           associated protein.
          Length = 275

 Score =  209 bits (510), Expect = 6e-54
 Identities = 98/172 (56%), Positives = 125/172 (72%)
 Frame = +2

Query: 80  VDAKVDIMYGLKTVLSQIEIAVARRSKDLPQIAPRLVAVSKIKPVELIVEAYNAGQRHFG 259
           + A++ +   L+ V  +++ AVARR +DLP I PRLVAVSK KP ++++EAY  GQR FG
Sbjct: 7   MSAELGVGCALRAVNERVQQAVARRPRDLPAIQPRLVAVSKTKPADMVIEAYGHGQRTFG 66

Query: 260 ENYVNELSDKASDPLILEKCKDIKWHFIGHLQTNKINKLLGSPGLFMVETVDSEKLADNL 439
           ENYV EL +KAS+P IL  C +IKWHFIGHLQ   +NKL+  P LFM+ETVDS KLAD +
Sbjct: 67  ENYVQELLEKASNPKILSLCPEIKWHFIGHLQKQNVNKLMAVPNLFMLETVDSVKLADKV 126

Query: 440 NKQWLKYRKEKERLRVMVQVNTSGEQAKSGLEPLETTKAVEHILENCPNLDF 595
           N  W + +   ERL+VMVQ+NTSGE++K GL P ET   VEHI   CPNL+F
Sbjct: 127 NSSWQR-KGSPERLKVMVQINTSGEESKHGLPPSETIAIVEHINAKCPNLEF 177


>M14642-1|AAA51745.1|  396|Homo sapiens APOA4 protein.
          Length = 396

 Score = 32.7 bits (71), Expect = 1.0
 Identities = 22/59 (37%), Positives = 34/59 (57%), Gaps = 1/59 (1%)
 Frame = +2

Query: 416 SEKLADNLNKQWLKYRKEKERLRVMVQVNTSGEQAKSGLEPLETTKAVEHIL-ENCPNL 589
           S+K+ DNL +  L+ R E    ++  QVNT  EQ +  L+PL   + +E +L EN  +L
Sbjct: 121 SQKIGDNLRE--LQQRLEPYADQLRTQVNTQAEQLRRQLDPL--AQRMERVLRENADSL 175


>M13654-1|AAA51744.1|  396|Homo sapiens APOA4 protein.
          Length = 396

 Score = 32.7 bits (71), Expect = 1.0
 Identities = 22/59 (37%), Positives = 34/59 (57%), Gaps = 1/59 (1%)
 Frame = +2

Query: 416 SEKLADNLNKQWLKYRKEKERLRVMVQVNTSGEQAKSGLEPLETTKAVEHIL-ENCPNL 589
           S+K+ DNL +  L+ R E    ++  QVNT  EQ +  L+PL   + +E +L EN  +L
Sbjct: 121 SQKIGDNLRE--LQQRLEPYADQLRTQVNTQAEQLRRQLDPL--AQRMERVLRENADSL 175


>BC067299-1|AAH67299.1|  490|Homo sapiens Mdm4, transformed 3T3 cell
           double minute 4, p53 binding protein (mouse) protein.
          Length = 490

 Score = 31.9 bits (69), Expect = 1.8
 Identities = 19/80 (23%), Positives = 37/80 (46%), Gaps = 1/80 (1%)
 Frame = +2

Query: 326 IKWHFIGHLQTNKINKLLGSPGLFMVETVDSEKLADNLNKQWLKYRKEKERLRVMVQVNT 505
           + W F+G+L++N   +  GS  L   + V +  ++D  +  W       E+L V ++V  
Sbjct: 198 LPWWFLGNLRSNYTPRSNGSTDLQTNQDVGTAIVSDTTDDLWFLNESVSEQLGVGIKVEA 257

Query: 506 SG-EQAKSGLEPLETTKAVE 562
           +  EQ    +  +   K +E
Sbjct: 258 ADTEQTSEEVGKVSDKKVIE 277


>AY207458-1|AAO13494.1|  490|Homo sapiens Mdm4, transformed 3T3 cell
           double minute 4, p53 binding protein (mouse) protein.
          Length = 490

 Score = 31.9 bits (69), Expect = 1.8
 Identities = 19/80 (23%), Positives = 37/80 (46%), Gaps = 1/80 (1%)
 Frame = +2

Query: 326 IKWHFIGHLQTNKINKLLGSPGLFMVETVDSEKLADNLNKQWLKYRKEKERLRVMVQVNT 505
           + W F+G+L++N   +  GS  L   + V +  ++D  +  W       E+L V ++V  
Sbjct: 198 LPWWFLGNLRSNYTPRSNGSTDLQTNQDVGTAIVSDTTDDLWFLNESVSEQLGVGIKVEA 257

Query: 506 SG-EQAKSGLEPLETTKAVE 562
           +  EQ    +  +   K +E
Sbjct: 258 ADTEQTSEEVGKVSDKKVIE 277


>AL512306-5|CAI14100.1|  490|Homo sapiens Mdm4, transformed 3T3 cell
           double minute 4, p53 binding protein (mouse) protein.
          Length = 490

 Score = 31.9 bits (69), Expect = 1.8
 Identities = 19/80 (23%), Positives = 37/80 (46%), Gaps = 1/80 (1%)
 Frame = +2

Query: 326 IKWHFIGHLQTNKINKLLGSPGLFMVETVDSEKLADNLNKQWLKYRKEKERLRVMVQVNT 505
           + W F+G+L++N   +  GS  L   + V +  ++D  +  W       E+L V ++V  
Sbjct: 198 LPWWFLGNLRSNYTPRSNGSTDLQTNQDVGTAIVSDTTDDLWFLNESVSEQLGVGIKVEA 257

Query: 506 SG-EQAKSGLEPLETTKAVE 562
           +  EQ    +  +   K +E
Sbjct: 258 ADTEQTSEEVGKVSDKKVIE 277


>AL512306-3|CAI14098.1|  213|Homo sapiens Mdm4, transformed 3T3 cell
           double minute 4, p53 binding protein (mouse) protein.
          Length = 213

 Score = 31.9 bits (69), Expect = 1.8
 Identities = 19/80 (23%), Positives = 37/80 (46%), Gaps = 1/80 (1%)
 Frame = +2

Query: 326 IKWHFIGHLQTNKINKLLGSPGLFMVETVDSEKLADNLNKQWLKYRKEKERLRVMVQVNT 505
           + W F+G+L++N   +  GS  L   + V +  ++D  +  W       E+L V ++V  
Sbjct: 83  LPWWFLGNLRSNYTPRSNGSTDLQTNQDVGTAIVSDTTDDLWFLNESVSEQLGVGIKVEA 142

Query: 506 SG-EQAKSGLEPLETTKAVE 562
           +  EQ    +  +   K +E
Sbjct: 143 ADTEQTSEEVGKVSDKKVIE 162


>AK223228-1|BAD96948.1|  490|Homo sapiens mouse double minute 4
           homolog protein.
          Length = 490

 Score = 31.9 bits (69), Expect = 1.8
 Identities = 19/80 (23%), Positives = 37/80 (46%), Gaps = 1/80 (1%)
 Frame = +2

Query: 326 IKWHFIGHLQTNKINKLLGSPGLFMVETVDSEKLADNLNKQWLKYRKEKERLRVMVQVNT 505
           + W F+G+L++N   +  GS  L   + V +  ++D  +  W       E+L V ++V  
Sbjct: 198 LPWWFLGNLRSNYTPRSNGSTDLQTNQDVGTAIVSDTTDDLWFLNESVSEQLGVGIKVEA 257

Query: 506 SG-EQAKSGLEPLETTKAVE 562
           +  EQ    +  +   K +E
Sbjct: 258 ADTEQTSEEVGKVSDKKVIE 277


>AF007111-1|AAB62928.1|  490|Homo sapiens MDM2-like p53-binding
           protein protein.
          Length = 490

 Score = 31.9 bits (69), Expect = 1.8
 Identities = 19/80 (23%), Positives = 37/80 (46%), Gaps = 1/80 (1%)
 Frame = +2

Query: 326 IKWHFIGHLQTNKINKLLGSPGLFMVETVDSEKLADNLNKQWLKYRKEKERLRVMVQVNT 505
           + W F+G+L++N   +  GS  L   + V +  ++D  +  W       E+L V ++V  
Sbjct: 198 LPWWFLGNLRSNYTPRSNGSTDLQTNQDVGTAIVSDTTDDLWFLNESVSEQLGVGIKVEA 257

Query: 506 SG-EQAKSGLEPLETTKAVE 562
           +  EQ    +  +   K +E
Sbjct: 258 ADTEQTSEEVGKVSDKKVIE 277


>AL590543-3|CAI10943.1|  722|Homo sapiens chromosome 6 open reading
           frame 97 protein.
          Length = 722

 Score = 31.5 bits (68), Expect = 2.3
 Identities = 21/81 (25%), Positives = 40/81 (49%), Gaps = 5/81 (6%)
 Frame = +2

Query: 308 LEKCKDIKWHFIGHLQTNKINKLLGSPGLFMVETVDSEKLADNLNK-----QWLKYRKEK 472
           L  C+D+       L     N+L  S  L  ++T++  K  ++LNK     + +K + EK
Sbjct: 549 LNTCRDLHTELKAKLADT--NELKASAWLHFIKTLEQTKAIEDLNKSRDQLEKMKEKAEK 606

Query: 473 ERLRVMVQVNTSGEQAKSGLE 535
           + + V  +++T+  +AK   E
Sbjct: 607 KLMSVKSELDTTEHEAKENKE 627


>AL359494-1|CAH71980.1|  722|Homo sapiens chromosome 6 open reading
           frame 97 protein.
          Length = 722

 Score = 31.5 bits (68), Expect = 2.3
 Identities = 21/81 (25%), Positives = 40/81 (49%), Gaps = 5/81 (6%)
 Frame = +2

Query: 308 LEKCKDIKWHFIGHLQTNKINKLLGSPGLFMVETVDSEKLADNLNK-----QWLKYRKEK 472
           L  C+D+       L     N+L  S  L  ++T++  K  ++LNK     + +K + EK
Sbjct: 549 LNTCRDLHTELKAKLADT--NELKASAWLHFIKTLEQTKAIEDLNKSRDQLEKMKEKAEK 606

Query: 473 ERLRVMVQVNTSGEQAKSGLE 535
           + + V  +++T+  +AK   E
Sbjct: 607 KLMSVKSELDTTEHEAKENKE 627


>BC127772-1|AAI27773.1|  863|Homo sapiens KIF5C protein protein.
          Length = 863

 Score = 30.7 bits (66), Expect = 4.1
 Identities = 15/51 (29%), Positives = 31/51 (60%)
 Frame = +2

Query: 410 VDSEKLADNLNKQWLKYRKEKERLRVMVQVNTSGEQAKSGLEPLETTKAVE 562
           ++ EKL+ + NK  ++ ++ + +L  ++ +N   EQA+  L+ LE T + E
Sbjct: 650 LEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQAREDLKGLEETVSRE 700


>BC110287-1|AAI10288.1|  725|Homo sapiens KIF5C protein protein.
          Length = 725

 Score = 30.7 bits (66), Expect = 4.1
 Identities = 15/51 (29%), Positives = 31/51 (60%)
 Frame = +2

Query: 410 VDSEKLADNLNKQWLKYRKEKERLRVMVQVNTSGEQAKSGLEPLETTKAVE 562
           ++ EKL+ + NK  ++ ++ + +L  ++ +N   EQA+  L+ LE T + E
Sbjct: 512 LEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQAREDLKGLEETVSRE 562


>AC108512-1|AAX82030.1|  684|Homo sapiens unknown protein.
          Length = 684

 Score = 30.7 bits (66), Expect = 4.1
 Identities = 15/51 (29%), Positives = 31/51 (60%)
 Frame = +2

Query: 410 VDSEKLADNLNKQWLKYRKEKERLRVMVQVNTSGEQAKSGLEPLETTKAVE 562
           ++ EKL+ + NK  ++ ++ + +L  ++ +N   EQA+  L+ LE T + E
Sbjct: 471 LEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQAREDLKGLEETVSRE 521


>AB209191-1|BAD92428.1|  265|Homo sapiens Kinesin heavy chain
           isoform 5C variant protein.
          Length = 265

 Score = 30.7 bits (66), Expect = 4.1
 Identities = 15/51 (29%), Positives = 31/51 (60%)
 Frame = +2

Query: 410 VDSEKLADNLNKQWLKYRKEKERLRVMVQVNTSGEQAKSGLEPLETTKAVE 562
           ++ EKL+ + NK  ++ ++ + +L  ++ +N   EQA+  L+ LE T + E
Sbjct: 52  LEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQAREDLKGLEETVSRE 102


>AB011103-1|BAA25457.2|  999|Homo sapiens KIAA0531 protein protein.
          Length = 999

 Score = 30.7 bits (66), Expect = 4.1
 Identities = 15/51 (29%), Positives = 31/51 (60%)
 Frame = +2

Query: 410 VDSEKLADNLNKQWLKYRKEKERLRVMVQVNTSGEQAKSGLEPLETTKAVE 562
           ++ EKL+ + NK  ++ ++ + +L  ++ +N   EQA+  L+ LE T + E
Sbjct: 786 LEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQAREDLKGLEETVSRE 836


>AL121586-7|CAB89415.1| 2442|Homo sapiens centrosomal protein 250kDa
           protein.
          Length = 2442

 Score = 30.3 bits (65), Expect = 5.4
 Identities = 16/57 (28%), Positives = 28/57 (49%)
 Frame = +2

Query: 329 KWHFIGHLQTNKINKLLGSPGLFMVETVDSEKLADNLNKQWLKYRKEKERLRVMVQV 499
           +W   G     ++ KL G       +TVD +   D+L+K+    +K +E LR  ++V
Sbjct: 425 QWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEV 481


>AF049105-1|AAC07988.1| 2442|Homo sapiens centrosomal
           Nek2-associated protein 1 protein.
          Length = 2442

 Score = 30.3 bits (65), Expect = 5.4
 Identities = 16/57 (28%), Positives = 28/57 (49%)
 Frame = +2

Query: 329 KWHFIGHLQTNKINKLLGSPGLFMVETVDSEKLADNLNKQWLKYRKEKERLRVMVQV 499
           +W   G     ++ KL G       +TVD +   D+L+K+    +K +E LR  ++V
Sbjct: 425 QWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEV 481


>AF022655-1|AAC06349.1| 2442|Homo sapiens cep250 centrosome
           associated protein protein.
          Length = 2442

 Score = 30.3 bits (65), Expect = 5.4
 Identities = 16/57 (28%), Positives = 28/57 (49%)
 Frame = +2

Query: 329 KWHFIGHLQTNKINKLLGSPGLFMVETVDSEKLADNLNKQWLKYRKEKERLRVMVQV 499
           +W   G     ++ KL G       +TVD +   D+L+K+    +K +E LR  ++V
Sbjct: 425 QWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEV 481


>AB209115-1|BAD92352.1| 1065|Homo sapiens restin isoform a variant
           protein.
          Length = 1065

 Score = 29.5 bits (63), Expect = 9.4
 Identities = 33/151 (21%), Positives = 70/151 (46%), Gaps = 6/151 (3%)
 Frame = +2

Query: 62  QLMTSEVDAKVDIMYGLKTVLSQIEIAVARRSKDLPQIAPRLVAVSKIKPVELIVEAYNA 241
           +L T     ++D  + ++ + +Q +   A  +K++  +  +L+ V  IK  E  +EA  +
Sbjct: 398 ELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKV--IKEKENSLEAIRS 455

Query: 242 GQRHFGENYVNELSD---KASDPLIL-EKCKDIKWHFIGHLQTNK--INKLLGSPGLFMV 403
                 + ++ E+ D   K  +  I  EK  +     +   ++ +  +NKL      F +
Sbjct: 456 KLDKAEDQHLVEMEDTLNKLQEAEIKKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNM 515

Query: 404 ETVDSEKLADNLNKQWLKYRKEKERLRVMVQ 496
            + D EKL +NL     K+R++ ER   +++
Sbjct: 516 LSSDLEKLRENLADMEAKFREKDEREEQLIK 546


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 80,167,087
Number of Sequences: 237096
Number of extensions: 1647323
Number of successful extensions: 3124
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 3043
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3121
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 6268037466
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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