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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= P5PG0648
         (570 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI0000D56C93 Cluster: PREDICTED: similar to CG3400-PG,...   161   1e-38
UniRef50_UPI000051A380 Cluster: PREDICTED: similar to 6-phosphof...   153   4e-36
UniRef50_A7SNT5 Cluster: Predicted protein; n=1; Nematostella ve...   135   8e-31
UniRef50_Q16875 Cluster: 6-phosphofructo-2-kinase/fructose-2,6-b...   120   2e-26
UniRef50_Q4SSV4 Cluster: Chromosome undetermined SCAF14347, whol...   114   2e-24
UniRef50_Q9LL39 Cluster: Fructose-6-phosphate 2-kinase/fructose-...   113   4e-24
UniRef50_Q16877 Cluster: 6-phosphofructo-2-kinase/fructose-2,6-b...   112   6e-24
UniRef50_Q9NKN9 Cluster: 6-phosphofructo-2-kinase/fructose-2,6-b...   103   4e-21
UniRef50_Q4T6Q0 Cluster: Chromosome undetermined SCAF8673, whole...   102   7e-21
UniRef50_Q54SI2 Cluster: Putative uncharacterized protein; n=1; ...   101   1e-20
UniRef50_Q4DRA6 Cluster: 6-phosphofructo-2-kinase/fructose-2, 6-...    98   1e-19
UniRef50_UPI0000E1FC87 Cluster: PREDICTED: 6-phosphofructo-2-kin...    96   6e-19
UniRef50_A4H3P1 Cluster: 6-phosphofructo-2-kinase/fructose-2,6-b...    96   6e-19
UniRef50_A0DV08 Cluster: Chromosome undetermined scaffold_65, wh...    94   2e-18
UniRef50_Q75B14 Cluster: ADL237Cp; n=1; Eremothecium gossypii|Re...    94   2e-18
UniRef50_Q4PB80 Cluster: Putative uncharacterized protein; n=1; ...    91   1e-17
UniRef50_Q8MMY0 Cluster: Similar to Solanum tuberosum (Potato). ...    91   2e-17
UniRef50_Q6PY95 Cluster: 6-phosphofructo-2-kinase; n=2; Trypanos...    90   4e-17
UniRef50_Q01H81 Cluster: Fructose-6-phosphate 2-kinase/fructose-...    87   3e-16
UniRef50_Q8TFH0 Cluster: 6-phosphofructo-2-kinase; n=1; Schizosa...    85   8e-16
UniRef50_A3AGY1 Cluster: Putative uncharacterized protein; n=3; ...    85   1e-15
UniRef50_Q6C045 Cluster: Yarrowia lipolytica chromosome F of str...    85   1e-15
UniRef50_Q9UTK9 Cluster: 6-phosphofructo-2-kinase; n=1; Schizosa...    84   3e-15
UniRef50_Q9UTE1 Cluster: 6-phosphofructo-2-kinase; n=1; Schizosa...    83   3e-15
UniRef50_Q5KB65 Cluster: 6-phosphofructo-2-kinase/fructose-2, 6-...    82   8e-15
UniRef50_Q726G1 Cluster: 6-phosphofructo-2-kinase/fructose-2, 6-...    81   2e-14
UniRef50_P32604 Cluster: Fructose-2,6-bisphosphatase; n=40; Fung...    80   3e-14
UniRef50_P40433 Cluster: 6-phosphofructo-2-kinase 1; n=6; Ascomy...    80   4e-14
UniRef50_A3LR80 Cluster: 6-phosphofructo-2-kinase; n=6; Saccharo...    78   2e-13
UniRef50_Q5KNM5 Cluster: Cytoplasm protein, putative; n=4; Filob...    77   4e-13
UniRef50_Q6BT67 Cluster: Similar to CA2215|CaPFK26 Candida albic...    49   5e-13
UniRef50_Q06137 Cluster: Putative 6-phosphofructo-2-kinase/fruct...    76   5e-13
UniRef50_Q6FWD2 Cluster: Similar to sp|P40433 Saccharomyces cere...    75   1e-12
UniRef50_Q4PFU8 Cluster: Putative uncharacterized protein; n=1; ...    73   4e-12
UniRef50_Q6C8B6 Cluster: Similar to KLLA0B05709g Kluyveromyces l...    70   4e-11
UniRef50_A3LYR6 Cluster: 6-phosphofructose-2-kinase; n=3; Saccha...    70   4e-11
UniRef50_Q17A04 Cluster: 6-phosphofructo-2-kinase/fructose-2, 6-...    69   8e-11
UniRef50_A0BXN8 Cluster: Chromosome undetermined scaffold_135, w...    69   8e-11
UniRef50_Q6BVZ2 Cluster: Debaryomyces hansenii chromosome B of s...    65   1e-09
UniRef50_A7TP12 Cluster: Putative uncharacterized protein; n=1; ...    65   1e-09
UniRef50_Q75CV1 Cluster: ACL185Cp; n=2; Saccharomycetaceae|Rep: ...    62   9e-09
UniRef50_Q59WJ3 Cluster: Putative uncharacterized protein; n=1; ...    62   9e-09
UniRef50_Q4Q9G0 Cluster: 6-phosphofructo-2-kinase/fructose-2,6-b...    62   1e-08
UniRef50_A3GFN4 Cluster: 6-phosphofructo-2-kinase; n=2; Pichia s...    59   8e-08
UniRef50_A5DTU6 Cluster: Putative uncharacterized protein; n=1; ...    56   4e-07
UniRef50_A5DGB7 Cluster: Putative uncharacterized protein; n=1; ...    56   4e-07
UniRef50_Q4VBA9 Cluster: PFKFB1 protein; n=6; Eutheria|Rep: PFKF...    56   6e-07
UniRef50_Q6CVK4 Cluster: Kluyveromyces lactis strain NRRL Y-1140...    56   6e-07
UniRef50_A7EQN2 Cluster: Putative uncharacterized protein; n=1; ...    53   4e-06
UniRef50_Q0URN0 Cluster: Putative uncharacterized protein; n=1; ...    53   5e-06
UniRef50_A1CQU3 Cluster: 6-phosphofructo-2-kinase 1; n=7; Euroti...    52   7e-06
UniRef50_Q1E4N6 Cluster: 6-phosphofructo-2-kinase; n=1; Coccidio...    52   1e-05
UniRef50_A6RRU2 Cluster: Putative uncharacterized protein; n=1; ...    52   1e-05
UniRef50_Q9URZ7 Cluster: 6-phosphofructo-2-kinase; n=1; Schizosa...    51   2e-05
UniRef50_Q1E494 Cluster: Putative uncharacterized protein; n=1; ...    50   3e-05
UniRef50_Q9P522 Cluster: Related to 6-phosphofructo-2-kinase; n=...    48   2e-04
UniRef50_Q57VQ2 Cluster: 6-phosphofructo-2-kinase/fructose-2, 6-...    46   5e-04
UniRef50_Q4DA36 Cluster: 6-phosphofructo-2-kinase/fructose-2, 6-...    46   6e-04
UniRef50_A7THC8 Cluster: Putative uncharacterized protein; n=1; ...    45   0.001
UniRef50_Q8X0M5 Cluster: Related to 6-phosphofructo-2-kinase/fru...    45   0.001
UniRef50_A7EUT1 Cluster: Putative uncharacterized protein; n=1; ...    44   0.003
UniRef50_Q4QIL3 Cluster: 6-phosphofructo-2-kinase-like protein; ...    41   0.023
UniRef50_Q75AV3 Cluster: ADL183Cp; n=1; Eremothecium gossypii|Re...    41   0.023
UniRef50_Q73Y75 Cluster: Putative uncharacterized protein; n=1; ...    39   0.072
UniRef50_A0LQR4 Cluster: Putative uncharacterized protein; n=1; ...    39   0.072
UniRef50_A3YZI7 Cluster: Putative uncharacterized protein; n=1; ...    37   0.29 
UniRef50_Q8BRU8 Cluster: Adult male aorta and vein cDNA, RIKEN f...    37   0.38 
UniRef50_Q0LCD2 Cluster: Putative uncharacterized protein; n=1; ...    37   0.38 
UniRef50_Q6FVI9 Cluster: Similar to sp|Q12471 Saccharomyces cere...    37   0.38 
UniRef50_Q8XUM1 Cluster: Adenylyl-sulfate kinase; n=2; Ralstonia...    36   0.51 
UniRef50_Q15XY1 Cluster: AAA ATPase, central region; n=1; Pseudo...    36   0.67 
UniRef50_Q382A0 Cluster: Putative uncharacterized protein; n=1; ...    36   0.88 
UniRef50_Q12471 Cluster: 6-phosphofructo-2-kinase 2; n=2; Saccha...    36   0.88 
UniRef50_A1ZHR3 Cluster: Putative uncharacterized protein; n=1; ...    35   1.2  
UniRef50_Q8YNC2 Cluster: All4644 protein; n=6; Cyanobacteria|Rep...    35   1.5  
UniRef50_O46079 Cluster: CG3587-PA; n=3; Diptera|Rep: CG3587-PA ...    35   1.5  
UniRef50_A0CEM5 Cluster: Chromosome undetermined scaffold_172, w...    35   1.5  
UniRef50_UPI0000D9C495 Cluster: PREDICTED: similar to pleckstrin...    34   2.0  
UniRef50_UPI0000DC2245 Cluster: integrin, alpha D; n=4; Eutheria...    34   2.0  
UniRef50_Q8IVG0 Cluster: Pleckstrin and Sec7 domain-containing p...    34   2.0  
UniRef50_A2QCT7 Cluster: Similarity to hypothetical protein EAA5...    34   2.0  
UniRef50_Q0SJ89 Cluster: Possible hydrolase; n=3; Bacteria|Rep: ...    34   2.7  
UniRef50_Q0M695 Cluster: Protein-tyrosine kinase; n=1; Caulobact...    33   3.6  
UniRef50_Q4PD00 Cluster: Putative uncharacterized protein; n=1; ...    33   3.6  
UniRef50_A5DQ35 Cluster: Putative uncharacterized protein; n=1; ...    33   3.6  
UniRef50_Q6ZSZ6 Cluster: Teashirt homolog 1; n=27; Tetrapoda|Rep...    33   3.6  
UniRef50_Q4SUU0 Cluster: Chromosome undetermined SCAF13842, whol...    33   4.7  
UniRef50_A4ZPY4 Cluster: DepD; n=3; Chromobacterium violaceum|Re...    33   4.7  
UniRef50_Q7QBY9 Cluster: ENSANGP00000014942; n=1; Anopheles gamb...    33   4.7  
UniRef50_Q6CP70 Cluster: Kluyveromyces lactis strain NRRL Y-1140...    33   4.7  
UniRef50_Q99456 Cluster: Keratin, type I cytoskeletal 12; n=251;...    33   4.7  
UniRef50_UPI00015B551A Cluster: PREDICTED: hypothetical protein;...    33   6.2  
UniRef50_Q98P10 Cluster: Sensor histidine kinase of two-componen...    33   6.2  
UniRef50_A4E6S7 Cluster: Putative uncharacterized protein; n=1; ...    33   6.2  
UniRef50_A0VJZ9 Cluster: Adenylyl-sulfate kinase; n=7; Proteobac...    33   6.2  
UniRef50_Q4DTE1 Cluster: Putative uncharacterized protein; n=2; ...    33   6.2  
UniRef50_P19532 Cluster: Transcription factor E3; n=32; Euteleos...    33   6.2  
UniRef50_UPI0000EBEE4D Cluster: PREDICTED: hypothetical protein;...    32   8.2  
UniRef50_Q72F24 Cluster: Putative uncharacterized protein; n=2; ...    32   8.2  
UniRef50_A6LX20 Cluster: Conserved hypothetical membrane spannin...    32   8.2  
UniRef50_A3A1N0 Cluster: Putative uncharacterized protein; n=1; ...    32   8.2  

>UniRef50_UPI0000D56C93 Cluster: PREDICTED: similar to CG3400-PG,
           isoform G; n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to CG3400-PG, isoform G - Tribolium castaneum
          Length = 476

 Score =  161 bits (391), Expect = 1e-38
 Identities = 74/136 (54%), Positives = 100/136 (73%), Gaps = 1/136 (0%)
 Frame = +2

Query: 158 ISQFAPLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYGSHDIFR 337
           + QFAPL++A+VGLP RGKS +A RL+R+LN+ G+  KV+D S+YRR+H+  Y SH+IFR
Sbjct: 25  LRQFAPLMVAMVGLPGRGKSLMAKRLSRYLNYTGDVCKVYDISDYRRKHIKTYASHEIFR 84

Query: 338 ADNQQGSAIRRQSAHEAVQDAVIWLKDGN-SVAIFDVTNITREQRRELSDYCLSDMGFRI 514
           ADN     IR+QS  EA+++A  WL++ N  VAI D  N++R QR E+ D     +GFR+
Sbjct: 85  ADNLPAWRIRQQSFREALEEAASWLQEPNHHVAILDGPNVSRAQREEIYDLVYCQLGFRV 144

Query: 515 LFIECVCEDQELLERN 562
           +FIECVCED  LLERN
Sbjct: 145 MFIECVCEDPVLLERN 160


>UniRef50_UPI000051A380 Cluster: PREDICTED: similar to
           6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
           (6PF-2-K/Fru-2,6-P2ASE liver isozyme) isoform 1; n=2;
           Apocrita|Rep: PREDICTED: similar to
           6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
           (6PF-2-K/Fru-2,6-P2ASE liver isozyme) isoform 1 - Apis
           mellifera
          Length = 476

 Score =  153 bits (370), Expect = 4e-36
 Identities = 73/154 (47%), Positives = 103/154 (66%), Gaps = 3/154 (1%)
 Frame = +2

Query: 110 EDKEKLLAPATIRSRRISQFAPLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSE 289
           +DK  +     ++S R  +FA ++IA+ GLP RGKSQ+A  L+R LNWNG+STK+   S+
Sbjct: 8   KDKISIRTQGIMKSPR--KFAGVVIAMCGLPGRGKSQVAQCLSRRLNWNGDSTKIMSVSD 65

Query: 290 YRRRHMALYG---SHDIFRADNQQGSAIRRQSAHEAVQDAVIWLKDGNSVAIFDVTNITR 460
           YRR+ +  YG   SH++FR D+   +A+R  +  +A+ D   WL  GNSVAI D T +TR
Sbjct: 66  YRRKRLEPYGEAVSHELFRPDHTANTALRALAQRDAMHDCAAWLTAGNSVAILDATLVTR 125

Query: 461 EQRRELSDYCLSDMGFRILFIECVCEDQELLERN 562
            QR E+ DY    +G+R+LFIECVC+D  +LERN
Sbjct: 126 AQRAEVFDYFSGQLGYRVLFIECVCDDPVVLERN 159


>UniRef50_A7SNT5 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 481

 Score =  135 bits (326), Expect = 8e-31
 Identities = 63/131 (48%), Positives = 85/131 (64%)
 Frame = +2

Query: 173 PLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYGSHDIFRADNQQ 352
           P +I LVGLPARGK+ +A +L R+LNW G   KVF+  EYRR+ + +   HD F+ DNQ+
Sbjct: 73  PTVIVLVGLPARGKTYMAKKLGRYLNWIGIQCKVFNVGEYRRKAVGMDKLHDFFKVDNQE 132

Query: 353 GSAIRRQSAHEAVQDAVIWLKDGNSVAIFDVTNITREQRRELSDYCLSDMGFRILFIECV 532
             AIRRQ A + + D   WL +G   AIFD TN TRE+RR + DYC    G++  F+E V
Sbjct: 133 AQAIRRQCAIDCLNDVSSWLDEGVQAAIFDATNTTRERRRMVLDYC-RRRGYKTFFMESV 191

Query: 533 CEDQELLERNI 565
           C + E++  NI
Sbjct: 192 CNNSEIVASNI 202


>UniRef50_Q16875 Cluster:
           6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
           (6PF-2-K/Fru- 2,6-P2ASE brain/placenta-type isozyme)
           (iPFK-2) (Renal carcinoma antigen NY-REN-56) [Includes:
           6-phosphofructo-2-kinase (EC 2.7.1.105);
           Fructose-2,6-bisphosphatase (EC 3.1.3.46)]; n=143;
           Deuterostomia|Rep:
           6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
           (6PF-2-K/Fru- 2,6-P2ASE brain/placenta-type isozyme)
           (iPFK-2) (Renal carcinoma antigen NY-REN-56) [Includes:
           6-phosphofructo-2-kinase (EC 2.7.1.105);
           Fructose-2,6-bisphosphatase (EC 3.1.3.46)] - Homo
           sapiens (Human)
          Length = 520

 Score =  120 bits (289), Expect = 2e-26
 Identities = 56/134 (41%), Positives = 87/134 (64%), Gaps = 1/134 (0%)
 Frame = +2

Query: 170 APLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYGSHDIFRADNQ 349
           +P +I +VGLPARGK+ ++ +L R+LNW G  TKVF+  EYRR  +  Y S++ FR DN+
Sbjct: 34  SPTVIVMVGLPARGKTYISKKLTRYLNWIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNE 93

Query: 350 QGSAIRRQSAHEAVQDAVIWL-KDGNSVAIFDVTNITREQRRELSDYCLSDMGFRILFIE 526
           +   +R+Q A  A++D   +L K+G  +A+FD TN TRE+R  +  +   +  F+  FIE
Sbjct: 94  EAMKVRKQCALAALRDVKSYLAKEGGQIAVFDATNTTRERRHMILHFA-KENDFKAFFIE 152

Query: 527 CVCEDQELLERNII 568
            VC+D  ++  NI+
Sbjct: 153 SVCDDPTVVASNIM 166


>UniRef50_Q4SSV4 Cluster: Chromosome undetermined SCAF14347, whole
           genome shotgun sequence; n=2; Tetraodontidae|Rep:
           Chromosome undetermined SCAF14347, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 610

 Score =  114 bits (274), Expect = 2e-24
 Identities = 64/156 (41%), Positives = 93/156 (59%), Gaps = 11/156 (7%)
 Frame = +2

Query: 134 PATIRSRRISQFA--PLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHM 307
           PA  R+     FA  P +I +VGLPARGK+ ++ +L R+LNW G  TKVF+  EYRR  +
Sbjct: 22  PAPRRAAGAPHFANPPTVIVMVGLPARGKTYISKKLTRYLNWIGMPTKVFNVGEYRREAV 81

Query: 308 ALYGSHDIFRADNQQGSAIRRQSAHEAVQDAVIWLKD-GNSVAIFDVTNITREQRRELSD 484
             Y S+D F+ DN+    IR+Q A  A++D   +LKD G  VA+FD TN TRE+R  + +
Sbjct: 82  KNYSSYDFFKPDNECAVKIRQQCALAALRDVKSYLKDEGGQVAVFDATNTTRERRSMILN 141

Query: 485 YCLSD--------MGFRILFIECVCEDQELLERNII 568
           +   +        +  +I FIE VC+D  ++  NI+
Sbjct: 142 FGAENDFKATVCFVCAQIFFIESVCDDPSVIASNIM 177


>UniRef50_Q9LL39 Cluster: Fructose-6-phosphate
           2-kinase/fructose-2,6-bisphosphatase; n=20;
           Magnoliophyta|Rep: Fructose-6-phosphate
           2-kinase/fructose-2,6-bisphosphatase - Arabidopsis
           thaliana (Mouse-ear cress)
          Length = 745

 Score =  113 bits (271), Expect = 4e-24
 Identities = 56/130 (43%), Positives = 81/130 (62%)
 Frame = +2

Query: 176 LLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYGSHDIFRADNQQG 355
           L I LVGLPARGK+  A +L R+L W G  TK F+  +YRR    +  S D FRADN +G
Sbjct: 344 LAIVLVGLPARGKTFTAAKLTRYLRWLGHDTKHFNVGKYRRLKHGVNMSADFFRADNPEG 403

Query: 356 SAIRRQSAHEAVQDAVIWLKDGNSVAIFDVTNITREQRRELSDYCLSDMGFRILFIECVC 535
              R + A  A++D + W+++G  V IFD TN TR +R  L    +++   +I+F+E +C
Sbjct: 404 VEARTEVAALAMEDMIAWMQEGGQVGIFDATNSTRVRRNMLMK--MAEGKCKIIFLETLC 461

Query: 536 EDQELLERNI 565
            D+ ++ERNI
Sbjct: 462 NDERIIERNI 471


>UniRef50_Q16877 Cluster:
           6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
           (6PF-2-K/Fru- 2,6-P2ASE testis-type isozyme) [Includes:
           6-phosphofructo-2-kinase (EC 2.7.1.105);
           Fructose-2,6-bisphosphatase (EC 3.1.3.46)]; n=78;
           Eumetazoa|Rep:
           6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
           (6PF-2-K/Fru- 2,6-P2ASE testis-type isozyme) [Includes:
           6-phosphofructo-2-kinase (EC 2.7.1.105);
           Fructose-2,6-bisphosphatase (EC 3.1.3.46)] - Homo
           sapiens (Human)
          Length = 469

 Score =  112 bits (269), Expect = 6e-24
 Identities = 54/133 (40%), Positives = 85/133 (63%), Gaps = 1/133 (0%)
 Frame = +2

Query: 173 PLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYGSHDIFRADNQQ 352
           P LI +VGLPARGK+ ++ +L R+LNW G  T+ F+  +YRR  +  Y S + F  DN++
Sbjct: 39  PTLIVMVGLPARGKTYISKKLTRYLNWIGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEE 98

Query: 353 GSAIRRQSAHEAVQDAVIWL-KDGNSVAIFDVTNITREQRRELSDYCLSDMGFRILFIEC 529
           G  IR+Q A  A++D   +L ++G  VA+FD TN TRE+R  + ++     G++  F+E 
Sbjct: 99  GLKIRKQCALAALRDVRRFLSEEGGHVAVFDATNTTRERRATIFNFG-EQNGYKTFFVES 157

Query: 530 VCEDQELLERNII 568
           +C D E++  NI+
Sbjct: 158 ICVDPEVIAANIV 170


>UniRef50_Q9NKN9 Cluster:
            6-phosphofructo-2-kinase/fructose-2,6-biphospha ta
            se,putative; n=2; Leishmania|Rep:
            6-phosphofructo-2-kinase/fructose-2,6-biphospha ta
            se,putative - Leishmania major
          Length = 2422

 Score =  103 bits (246), Expect = 4e-21
 Identities = 55/145 (37%), Positives = 85/145 (58%), Gaps = 8/145 (5%)
 Frame = +2

Query: 158  ISQFAPLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYGS--HDI 331
            IS    +++ +VGLP RGKS ++ RL R++NW G   KVF+   YRR+ + +  +   D 
Sbjct: 1755 ISDTVSVIVCMVGLPGRGKSFISKRLVRYMNWKGVPCKVFNAGNYRRQLLGVEATAGADF 1814

Query: 332  FRADNQQGSAIRRQSAHEAVQDAVIWLKDGN-SVAIFDVTNITREQRRELSDYCLSD--- 499
            F  DN QG+ +R + A  A +D V ++   + +V I D TN TR++R  LSDY   +   
Sbjct: 1815 FNPDNPQGAQLRERMAELACEDLVNFIASHSLAVGILDATNTTRKRRAWLSDYFQKEAQQ 1874

Query: 500  --MGFRILFIECVCEDQELLERNII 568
              + +R+LFIE VC D  ++  NI+
Sbjct: 1875 YAVPYRLLFIESVCTDDTIVTENIL 1899


>UniRef50_Q4T6Q0 Cluster: Chromosome undetermined SCAF8673, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF8673,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 476

 Score =  102 bits (244), Expect = 7e-21
 Identities = 59/155 (38%), Positives = 88/155 (56%), Gaps = 22/155 (14%)
 Frame = +2

Query: 170 APLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYGSHDIFRADNQ 349
           +P +I ++GLPARGK+ ++ +L R+LNW G  TKVF+   YRR  +  Y S+D FR DN+
Sbjct: 4   SPTVIVMIGLPARGKTYMSKKLTRYLNWIGVPTKVFNLGVYRREAVGTYKSYDFFRHDNE 63

Query: 350 QGSAIR---------------------RQSAHEAVQDAVIW-LKDGNSVAIFDVTNITRE 463
           +   IR                     RQ A  A+QD   + L++G  +A+FD TN TRE
Sbjct: 64  EAMKIRNAWGLGVCVCVFAEVACDCSCRQCALVALQDLKSYLLREGGQIAVFDATNTTRE 123

Query: 464 QRRELSDYCLSDMGFRILFIECVCEDQELLERNII 568
            RR+L      +  F++ F+E VC+D E++  NI+
Sbjct: 124 -RRDLILAFGKENAFKVFFVESVCDDPEVIAANIM 157


>UniRef50_Q54SI2 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 488

 Score =  101 bits (242), Expect = 1e-20
 Identities = 47/130 (36%), Positives = 73/130 (56%)
 Frame = +2

Query: 176 LLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYGSHDIFRADNQQG 355
           +++ +VGLPARGK+ +A ++ R LNW     KVF+  EYRR  +     HD F   N +G
Sbjct: 170 IVLVMVGLPARGKTYVARKICRMLNWMLVPAKVFNVGEYRRLRIGAGQPHDFFDPHNPEG 229

Query: 356 SAIRRQSAHEAVQDAVIWLKDGNSVAIFDVTNITREQRRELSDYCLSDMGFRILFIECVC 535
              R   A  A+ D + WL +G  V I+D TN T E+R+ +   C  +    ++++E +C
Sbjct: 230 IKARLHMAVAALDDMISWLHNGGRVGIYDATNSTNERRQLVEKRCTREK-MTVVYVESIC 288

Query: 536 EDQELLERNI 565
            D  ++E NI
Sbjct: 289 NDASVIEHNI 298


>UniRef50_Q4DRA6 Cluster: 6-phosphofructo-2-kinase/fructose-2,
           6-biphosphatase, putative; n=2; Trypanosoma cruzi|Rep:
           6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase,
           putative - Trypanosoma cruzi
          Length = 1023

 Score = 97.9 bits (233), Expect = 1e-19
 Identities = 51/145 (35%), Positives = 83/145 (57%), Gaps = 8/145 (5%)
 Frame = +2

Query: 158 ISQFAPLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYGSHD--I 331
           IS   PL++ +VGLP RGKS +A R++R+LNW G   +VF+   YRRR + + G+ D   
Sbjct: 495 ISGTVPLVVCMVGLPGRGKSFIAQRISRYLNWKGVPCRVFNAGNYRRRLLGVEGTSDAGF 554

Query: 332 FRADNQQGSAIRRQSAHEAVQDAVIWL-KDGNSVAIFDVTNITREQRRELSDYC-----L 493
           +  +N  G  +R + A  A +D V ++ +   +V +FD TN T+ +R  L ++       
Sbjct: 555 YDPNNANGKQMREKMAEFACEDLVEFISRHRIAVGVFDATNTTKARREHLVEFFNKAFKQ 614

Query: 494 SDMGFRILFIECVCEDQELLERNII 568
             M  R++FIE +C D  ++  NI+
Sbjct: 615 RHMESRVMFIESICNDDTIITENIL 639


>UniRef50_UPI0000E1FC87 Cluster: PREDICTED:
           6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
           isoform 9; n=2; Pan troglodytes|Rep: PREDICTED:
           6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
           isoform 9 - Pan troglodytes
          Length = 450

 Score = 95.9 bits (228), Expect = 6e-19
 Identities = 46/106 (43%), Positives = 70/106 (66%), Gaps = 1/106 (0%)
 Frame = +2

Query: 173 PLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYGSHDIFRADNQQ 352
           P LI +VGLPARGK+ ++ +L R+LNW G  T+ F+  +YRR  +  Y S + F  DN++
Sbjct: 39  PTLIVMVGLPARGKTYISKKLTRYLNWIGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEE 98

Query: 353 GSAIRRQSAHEAVQDAVIWL-KDGNSVAIFDVTNITREQRRELSDY 487
           G  IR+Q A  A++D   +L ++G  VA+FD TN TRE+R  + ++
Sbjct: 99  GLKIRKQCALAALRDVRRFLSEEGGHVAVFDATNTTRERRATIFNF 144


>UniRef50_A4H3P1 Cluster:
            6-phosphofructo-2-kinase/fructose-2,6-biphospha ta
            se,putative; n=1; Leishmania braziliensis|Rep:
            6-phosphofructo-2-kinase/fructose-2,6-biphospha ta
            se,putative - Leishmania braziliensis
          Length = 1972

 Score = 95.9 bits (228), Expect = 6e-19
 Identities = 51/145 (35%), Positives = 83/145 (57%), Gaps = 8/145 (5%)
 Frame = +2

Query: 158  ISQFAPLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYGS--HDI 331
            IS    +++ +VGLP RGKS ++ RL R++NW G   + F+   YRR+ +   G+   + 
Sbjct: 1217 ISDTVSVIVCMVGLPGRGKSFISKRLVRYMNWKGVPCRAFNAGNYRRQLLGAEGTAGAEF 1276

Query: 332  FRADNQQGSAIRRQSAHEAVQDAVIWLKDGN-SVAIFDVTNITREQRRELSDYCLSD--- 499
            F  DN QG+ +R + A  A +D V ++   + +V I D TN TR +R  L++Y   +   
Sbjct: 1277 FNPDNPQGAQLRERMAEFACEDLVRFIAAHSLAVGILDATNTTRRRRAWLAEYFQHEAQR 1336

Query: 500  --MGFRILFIECVCEDQELLERNII 568
              + +R+LFIE VC D  ++  NI+
Sbjct: 1337 HAVPYRLLFIESVCTDDTIVTENIL 1361


>UniRef50_A0DV08 Cluster: Chromosome undetermined scaffold_65, whole
           genome shotgun sequence; n=6; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_65,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 447

 Score = 94.3 bits (224), Expect = 2e-18
 Identities = 48/132 (36%), Positives = 75/132 (56%), Gaps = 2/132 (1%)
 Frame = +2

Query: 176 LLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYGSHDIFRADNQQG 355
           + I +VGLPARGK+ ++ +L R+LNW G + KVF+   YRR           F + N+Q 
Sbjct: 10  IAICMVGLPARGKTYISRKLHRYLNWLGYNCKVFNIGNYRREICGTECDKTFFDSKNEQA 69

Query: 356 SAIRRQSAHEAVQDAVIWLKDGNSVAIFDVTNITREQRRELSDYCLSD--MGFRILFIEC 529
           +  R + A  A+ D + +L     +AIFD TN T+ QRR +    LS      + L+IE 
Sbjct: 70  TKARNECAQMALNDLISFLNSDGEIAIFDGTNTTK-QRRNMVQCSLSQQCQNVQTLWIES 128

Query: 530 VCEDQELLERNI 565
           +C+D ++++ NI
Sbjct: 129 ICDDADVIQNNI 140


>UniRef50_Q75B14 Cluster: ADL237Cp; n=1; Eremothecium gossypii|Rep:
           ADL237Cp - Ashbya gossypii (Yeast) (Eremothecium
           gossypii)
          Length = 756

 Score = 94.3 bits (224), Expect = 2e-18
 Identities = 62/187 (33%), Positives = 98/187 (52%), Gaps = 10/187 (5%)
 Frame = +2

Query: 35  GFSEKTLVQENSNGARDLARATAMME-DKEKLLAPATIRSRRISQFAP---LLIALVGLP 202
           G   KT  + + NG     R  A    D   L    T     IS+  P   L++ +VGLP
Sbjct: 112 GLDNKTEARASGNGGLPRVRRKAPTTMDVPGLTRSKTSPDGMISKHDPGSKLVVVMVGLP 171

Query: 203 ARGKSQLAHRLARHLNWNGESTKVFDCS----EYRRRHMALYGSHDIFRADNQQGSAIRR 370
           A GKS + ++L+R LN++    KVF+      EY ++H  +      F   N +  A+R 
Sbjct: 172 ATGKSFITNKLSRFLNYSFYYCKVFNVGNTRREYGKQHELMEQDSRFFDPSNDEAKALRE 231

Query: 371 QSAHEAVQDAVIWLKDG-NSVAIFDVTNITREQRRELSDYCLS-DMGFRILFIECVCEDQ 544
           + A + + + + +L DG  SVAIFD TN T+E+RR++ D   S +    +LF+E +C D+
Sbjct: 232 KWAMDTLNELLDYLLDGPGSVAIFDATNSTQERRRKIYDKIKSRNSQLNVLFLESICSDR 291

Query: 545 ELLERNI 565
           + +E+NI
Sbjct: 292 QTVEKNI 298


>UniRef50_Q4PB80 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 648

 Score = 91.5 bits (217), Expect = 1e-17
 Identities = 46/141 (32%), Positives = 79/141 (56%), Gaps = 9/141 (6%)
 Frame = +2

Query: 170 APLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRR-HMALYGSHDI----- 331
           A +++ +VGLPARGKS +A+R+ ++L W     KVF+  + RR    A Y +  +     
Sbjct: 315 AKIVVCMVGLPARGKSYVANRVLKYLRWLEYDVKVFNVGQLRRALARAKYNTSGVKEDHT 374

Query: 332 ---FRADNQQGSAIRRQSAHEAVQDAVIWLKDGNSVAIFDVTNITREQRRELSDYCLSDM 502
              F   N     +R Q A E ++  + WLK G +V I D TN T+ +R+E++D    + 
Sbjct: 375 ASFFDPSNPSAYKLRSQMAEECLEQLIGWLKRGGNVGIHDATNSTQARRKEIADRIAKEP 434

Query: 503 GFRILFIECVCEDQELLERNI 565
             +++F+E +C D ++++ NI
Sbjct: 435 DLKLVFLESICTDPKVIDANI 455


>UniRef50_Q8MMY0 Cluster: Similar to Solanum tuberosum (Potato).
           Fructose-6-phosphate 2-
           kinase/fructose-2,6-bisphosphatase; n=2; Dictyostelium
           discoideum|Rep: Similar to Solanum tuberosum (Potato).
           Fructose-6-phosphate 2-
           kinase/fructose-2,6-bisphosphatase - Dictyostelium
           discoideum (Slime mold)
          Length = 501

 Score = 91.1 bits (216), Expect = 2e-17
 Identities = 42/131 (32%), Positives = 70/131 (53%)
 Frame = +2

Query: 176 LLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYGSHDIFRADNQQG 355
           +++ +VGLPA GK+ ++ ++   LNW G   KVF   +YRR  +      + F   N   
Sbjct: 110 IVVVMVGLPASGKTYISRKVRNLLNWMGVPAKVFTVGDYRRLRLGAKQPAEFFDPGNIDA 169

Query: 356 SAIRRQSAHEAVQDAVIWLKDGNSVAIFDVTNITREQRRELSDYCLSDMGFRILFIECVC 535
           S +R   A  A+ D + WL  G    IFD TN+T E+R+ +   C  +   +++F+E   
Sbjct: 170 SRVRLHMAVAAIDDMMAWLNSGAQAGIFDATNLTTERRQLILSRCAREGIEKVIFVESFM 229

Query: 536 EDQELLERNII 568
            D++ +E N+I
Sbjct: 230 TDKKKIETNMI 240


>UniRef50_Q6PY95 Cluster: 6-phosphofructo-2-kinase; n=2; Trypanosoma
           brucei|Rep: 6-phosphofructo-2-kinase - Trypanosoma
           brucei
          Length = 1023

 Score = 89.8 bits (213), Expect = 4e-17
 Identities = 51/146 (34%), Positives = 80/146 (54%), Gaps = 9/146 (6%)
 Frame = +2

Query: 158 ISQFAPLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYG--SHDI 331
           +S    L++ +VGLP RGKS +  R+AR+LNW G   +VF+   YRRR + + G  S D 
Sbjct: 512 VSDAVSLIVCMVGLPGRGKSFIGRRIARYLNWKGVPCRVFNVGNYRRRLLGVEGTCSADF 571

Query: 332 FRADNQQGSAIRRQSAHEAVQDAVIWLKDGN-SVAIFDVTNITREQRRELSDYCLS---- 496
           +   N Q   +R + A  A  D + ++     +  +FD TN T+ +R+ L + CL     
Sbjct: 572 YDPQNLQAKQMRDKVATLAFGDLIHFIAHHRVACGVFDATNTTKARRKYLLE-CLQQEAE 630

Query: 497 --DMGFRILFIECVCEDQELLERNII 568
             ++  R++FIE VC D  L+  NI+
Sbjct: 631 KHNINCRVIFIESVCNDLNLITENIL 656


>UniRef50_Q01H81 Cluster: Fructose-6-phosphate
           2-kinase/fructose-2,6-biphosphatase; n=2;
           Ostreococcus|Rep: Fructose-6-phosphate
           2-kinase/fructose-2,6-biphosphatase - Ostreococcus tauri
          Length = 650

 Score = 87.0 bits (206), Expect = 3e-16
 Identities = 53/143 (37%), Positives = 85/143 (59%), Gaps = 14/143 (9%)
 Frame = +2

Query: 179 LIALVGLPARGKSQLAHRLARHLN-WNGESTKVFDCSEYRRRHMALYGSHDIFRADNQQG 355
           ++ +VGLPARGK+ +A RL ++L  ++G +T+VF+  EYRRR      + D F  +N+  
Sbjct: 205 VLVMVGLPARGKTHMAKRLCQYLRFFHGANTRVFNVGEYRRRFAGAGQTADFFTKENK-- 262

Query: 356 SAIRRQSAHEAVQDAVIWL-------------KDGNSVAIFDVTNITREQRRELSDYCLS 496
            A R + A EA++D V +L              D   VAIFD TN T+E+RR L +  + 
Sbjct: 263 -AQRMKFAQEALKDMVDFLFQEDSMSNLEQRGVDSGRVAIFDATNSTKERRRWLVNQ-IG 320

Query: 497 DMGFRILFIECVCEDQELLERNI 565
            +  ++LFIE +C D++++E N+
Sbjct: 321 SLPLKLLFIESICTDEKVVEHNV 343


>UniRef50_Q8TFH0 Cluster: 6-phosphofructo-2-kinase; n=1;
           Schizosaccharomyces pombe|Rep: 6-phosphofructo-2-kinase
           - Schizosaccharomyces pombe (Fission yeast)
          Length = 474

 Score = 85.4 bits (202), Expect = 8e-16
 Identities = 44/130 (33%), Positives = 73/130 (56%), Gaps = 4/130 (3%)
 Frame = +2

Query: 188 LVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYGSHD---IFRADNQQGS 358
           +VGLPARGKS + ++L R+ NW   + K F+   +RR+H +   SHD    F   N++ S
Sbjct: 1   MVGLPARGKSYIVNKLVRYYNWLQYNCKAFNVGNFRRKHAS--HSHDDASFFDPSNEEAS 58

Query: 359 AIRRQSAHEAVQDAVIWLKDGNS-VAIFDVTNITREQRRELSDYCLSDMGFRILFIECVC 535
            +R   A + +   + W ++ +  V IFD TN T ++R+ + D+         LFIE +C
Sbjct: 59  KLRESFAMDTLDALLQWFEEEDGVVGIFDATNSTSKRRKAIVDHLSKVPYVTTLFIESIC 118

Query: 536 EDQELLERNI 565
            D++L+  N+
Sbjct: 119 NDEQLIAANM 128


>UniRef50_A3AGY1 Cluster: Putative uncharacterized protein; n=3; Oryza
            sativa|Rep: Putative uncharacterized protein - Oryza
            sativa subsp. japonica (Rice)
          Length = 1068

 Score = 85.0 bits (201), Expect = 1e-15
 Identities = 60/164 (36%), Positives = 83/164 (50%), Gaps = 34/164 (20%)
 Frame = +2

Query: 176  LLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRR-RH----MALYGSH----- 325
            L I LVGLPARGK+  A +L R+L W G  TK F+  +YRR +H     +L  S+     
Sbjct: 681  LAIVLVGLPARGKTFTAAKLTRYLRWLGHETKHFNVGKYRRLKHGINQTSLSASNSVEQT 740

Query: 326  -DIFRADNQQGSAIRRQSAHEAVQDAVIWLKDGNSVAIFDVTNITREQRREL----SDYC 490
             D FR DN++G   R + A  A++D + W+++G  V IFD TN TR +R  L       C
Sbjct: 741  ADFFRGDNKEGVEARNEVAALAMEDMLSWMQEGGQVGIFDATNSTRNRRNMLMKMAEGKC 800

Query: 491  LSD-------------------MGFRILFIECVCEDQELLERNI 565
             S                        I+F+E +C DQ +LERN+
Sbjct: 801  KSPKLIIVPIMNINRKRRTYKAYSCTIIFLETICNDQNVLERNM 844


>UniRef50_Q6C045 Cluster: Yarrowia lipolytica chromosome F of strain
           CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
           lipolytica|Rep: Yarrowia lipolytica chromosome F of
           strain CLIB122 of Yarrowia lipolytica - Yarrowia
           lipolytica (Candida lipolytica)
          Length = 816

 Score = 84.6 bits (200), Expect = 1e-15
 Identities = 68/213 (31%), Positives = 104/213 (48%), Gaps = 26/213 (12%)
 Frame = +2

Query: 5   ATVSSHETRSGF--SEKTLVQENSNGARDLARATAMM---EDKEKLLAPATIRSRRISQF 169
           A V +H T+     S  TL   +  G +   RAT +    + + K+     I SR +   
Sbjct: 140 AEVQTHPTKPVLQHSSSTLHIPDYTGHKRKPRATTLDVPGQTRSKVSPDGMISSRDVG-- 197

Query: 170 APLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRR-HMALYG--------- 319
           + L++ +VGLPARGKS + ++L R+LNW    T++F+    RR    A  G         
Sbjct: 198 SKLIVVMVGLPARGKSYITNKLCRYLNWQQHKTRIFNVGNTRREAKEAAVGSAGVEDPNE 257

Query: 320 ------SHD--IFRADNQQGSAIRRQSAHEAVQDAVIWLKDGN-SVAIFDVTNITREQRR 472
                 SHD   F  DN Q +A R   A E +Q  + ++  GN SV I D TN TR++R+
Sbjct: 258 EHHNETSHDASFFSPDNPQSTAQREIWAMETLQQCLDYVLHGNGSVGILDATNTTRDRRK 317

Query: 473 ELSDYC--LSDMGFRILFIECVCEDQELLERNI 565
            + +     S    ++LF+E VC D +++  NI
Sbjct: 318 NVFEKIQQQSKGQLKVLFLESVCTDIDIINSNI 350


>UniRef50_Q9UTK9 Cluster: 6-phosphofructo-2-kinase; n=1;
           Schizosaccharomyces pombe|Rep: 6-phosphofructo-2-kinase
           - Schizosaccharomyces pombe (Fission yeast)
          Length = 432

 Score = 83.8 bits (198), Expect = 3e-15
 Identities = 54/170 (31%), Positives = 85/170 (50%), Gaps = 3/170 (1%)
 Frame = +2

Query: 65  NSNGARDLARATAMMEDKEKL--LAPATIRSRRISQFAPLLIALVGLPARGKSQLAHRLA 238
           N N  R   R++  + D EK   + P +  S  +     L+I + GLPARGKS +A  + 
Sbjct: 14  NPNMLRAANRSSEALLDNEKFGGVQPYSTESGMLFHAGKLVIIMSGLPARGKSNIAVSID 73

Query: 239 RHLNWNGESTKVFDCSEYRRRHMALYGSHDIFRADNQQGSAIRRQSAHEAVQDAVIW-LK 415
           R+L W G + + +  ++Y         S  +  A ++     R  +    + D  I+ LK
Sbjct: 74  RYLRWLGFNCRFYSLAKYIDERTREMTSSPVKSAASENHVFSRNDTIERCLADLEIFLLK 133

Query: 416 DGNSVAIFDVTNITREQRRELSDYCLSDMGFRILFIECVCEDQELLERNI 565
           +   VAI+D TN TR  RR L D    + GF+ILFIE +C  ++++  NI
Sbjct: 134 EKGQVAIYDATNGTRRTRRILYDR-FKNCGFKILFIESLCNKEDVINANI 182


>UniRef50_Q9UTE1 Cluster: 6-phosphofructo-2-kinase; n=1;
           Schizosaccharomyces pombe|Rep: 6-phosphofructo-2-kinase
           - Schizosaccharomyces pombe (Fission yeast)
          Length = 592

 Score = 83.4 bits (197), Expect = 3e-15
 Identities = 48/133 (36%), Positives = 69/133 (51%), Gaps = 3/133 (2%)
 Frame = +2

Query: 176 LLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMA-LYG-SHDIFRADNQ 349
           L+I LVG+PA GKS +  +L+R+ NW   + + F   + RR   A  Y  S D F   N+
Sbjct: 144 LIIILVGIPATGKSYIGSKLSRYYNWLKYNCRFFSVGDKRREEGASTYSMSADFFDIKNE 203

Query: 350 QGSAIRRQSAHEAVQDAVIWLKDGNSV-AIFDVTNITREQRRELSDYCLSDMGFRILFIE 526
           +    R   A E ++D + W+   N V  I D TN T E+R+ L D    +    I+F+E
Sbjct: 204 ETFKFRENVALETLEDLLHWMIHENGVIGILDATNSTHERRKHLYDRISKEADIGIMFLE 263

Query: 527 CVCEDQELLERNI 565
            +C D  L E NI
Sbjct: 264 SLCTDDILFEENI 276


>UniRef50_Q5KB65 Cluster: 6-phosphofructo-2-kinase/fructose-2,
           6-bisphosphatase bifunctional enzyme, putative; n=1;
           Filobasidiella neoformans|Rep:
           6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase
           bifunctional enzyme, putative - Cryptococcus neoformans
           (Filobasidiella neoformans)
          Length = 658

 Score = 82.2 bits (194), Expect = 8e-15
 Identities = 45/141 (31%), Positives = 77/141 (54%), Gaps = 9/141 (6%)
 Frame = +2

Query: 170 APLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRR--RHMALYG-------S 322
           A +++A+VGLPARGKS L++RL R+L W   + +VF+  + RR     AL         S
Sbjct: 170 AKIVVAMVGLPARGKSYLSNRLMRYLRWLEYNVQVFNVGQLRRSKARSALQAGQGKVDHS 229

Query: 323 HDIFRADNQQGSAIRRQSAHEAVQDAVIWLKDGNSVAIFDVTNITREQRRELSDYCLSDM 502
              F   + + +  R + A E+++  + WLK   +V I D TN T ++R ++      + 
Sbjct: 230 ATYFSHSDAEATKKREELAEESLESLIAWLKKEGNVGIMDATNSTIDRREKIKKRIDKEP 289

Query: 503 GFRILFIECVCEDQELLERNI 565
           G ++L++E  C+D  ++  NI
Sbjct: 290 GLQVLYLESFCDDPVVIATNI 310


>UniRef50_Q726G1 Cluster: 6-phosphofructo-2-kinase/fructose-2,
           6-biphosphatase; n=4; Desulfovibrionaceae|Rep:
           6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase -
           Desulfovibrio vulgaris (strain Hildenborough / ATCC
           29579 / NCIMB8303)
          Length = 420

 Score = 80.6 bits (190), Expect = 2e-14
 Identities = 53/144 (36%), Positives = 77/144 (53%), Gaps = 1/144 (0%)
 Frame = +2

Query: 137 ATIRSRRISQFAPLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALY 316
           +TI + R      L +A+VGLPARGKS LA R+   L   G    +F+  E RR  +   
Sbjct: 9   STISASRGLTVKKLYVAMVGLPARGKSTLAKRIREGLEAEGLRVGIFNNGELRRTRLGRD 68

Query: 317 G-SHDIFRADNQQGSAIRRQSAHEAVQDAVIWLKDGNSVAIFDVTNITREQRRELSDYCL 493
             + + +  DN +G A R + A E V  A  +L  G +VAI D TN +R  RR + +  L
Sbjct: 69  STAPEFYHPDNAEGRARREELAQENVAHARAFLAGGGNVAILDATNASR-ARRAMLEARL 127

Query: 494 SDMGFRILFIECVCEDQELLERNI 565
           +D    +LF+EC  +D  LLE ++
Sbjct: 128 TD--HPLLFVECRNDDPVLLEASL 149


>UniRef50_P32604 Cluster: Fructose-2,6-bisphosphatase; n=40;
           Fungi/Metazoa group|Rep: Fructose-2,6-bisphosphatase -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 452

 Score = 80.2 bits (189), Expect = 3e-14
 Identities = 44/129 (34%), Positives = 71/129 (55%), Gaps = 2/129 (1%)
 Frame = +2

Query: 182 IALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMA-LYGSHDIFRADNQQGS 358
           + +VGLPARGKS ++ ++ R+L+W     K F+   YRR     +    + F  +N    
Sbjct: 16  VIMVGLPARGKSFISQKIIRYLSWLSIKAKCFNVGNYRRDVSGNVPMDAEFFNFENTDNF 75

Query: 359 AIRRQSAHEAVQDAV-IWLKDGNSVAIFDVTNITREQRRELSDYCLSDMGFRILFIECVC 535
            +R  +A  A++D V  + K+  SVA+FD TN TR++R+ L D C  +   + +F+E   
Sbjct: 76  KLRELAAQNAIKDIVNFFTKEDGSVAVFDATNSTRKRRKWLKDICEKN-NIQPMFLESWS 134

Query: 536 EDQELLERN 562
            D EL+  N
Sbjct: 135 NDHELIINN 143


>UniRef50_P40433 Cluster: 6-phosphofructo-2-kinase 1; n=6;
           Ascomycota|Rep: 6-phosphofructo-2-kinase 1 -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 827

 Score = 79.8 bits (188), Expect = 4e-14
 Identities = 47/136 (34%), Positives = 78/136 (57%), Gaps = 6/136 (4%)
 Frame = +2

Query: 176 LLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYGSHD----IFRAD 343
           L+I +VGLPA GKS + ++L+R LN++    KVF+    RR+    +G  D     F   
Sbjct: 184 LVIVMVGLPATGKSFITNKLSRFLNYSLYYCKVFNVGNTRRKFAKEHGLKDQDSKFFEPK 243

Query: 344 NQQGSAIRRQSAHEAVQDAVIWLKDGN-SVAIFDVTNITREQRRE-LSDYCLSDMGFRIL 517
           N   + +R + A + + + + +L +G+ SV IFD TN +RE+R+  L+         ++L
Sbjct: 244 NADSTRLRDKWAMDTLDELLDYLLEGSGSVGIFDATNTSRERRKNVLARIRKRSPHLKVL 303

Query: 518 FIECVCEDQELLERNI 565
           F+E VC D  L+++NI
Sbjct: 304 FLESVCSDHALVQKNI 319


>UniRef50_A3LR80 Cluster: 6-phosphofructo-2-kinase; n=6;
           Saccharomycetales|Rep: 6-phosphofructo-2-kinase - Pichia
           stipitis (Yeast)
          Length = 547

 Score = 77.8 bits (183), Expect = 2e-13
 Identities = 47/142 (33%), Positives = 72/142 (50%), Gaps = 3/142 (2%)
 Frame = +2

Query: 149 SRRISQFAPLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYGSHD 328
           S R+     + IAL GLP RGK+ L+  L R+L W G  T  F    YRR       +HD
Sbjct: 88  SGRLFHAGKICIALAGLPGRGKTHLSVSLTRYLRWLGVKTHSFHLGNYRRASAEDDVTHD 147

Query: 329 IF--RADNQQGSAIRRQSAHEAVQDAVIWLK-DGNSVAIFDVTNITREQRRELSDYCLSD 499
           +F    ++++ + IR +   E + D + + K D   VAI+D  N   E R  L     +D
Sbjct: 148 LFVPSPNSKRANEIRNKIVDECLNDMLNFFKNDKGQVAIYDAVNALPEYRLALQKK-FTD 206

Query: 500 MGFRILFIECVCEDQELLERNI 565
           M  ++LFIE +  D  ++ +N+
Sbjct: 207 MNIQVLFIESLVTDDAIIMKNM 228


>UniRef50_Q5KNM5 Cluster: Cytoplasm protein, putative; n=4;
           Filobasidiella neoformans|Rep: Cytoplasm protein,
           putative - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 605

 Score = 76.6 bits (180), Expect = 4e-13
 Identities = 44/153 (28%), Positives = 82/153 (53%), Gaps = 6/153 (3%)
 Frame = +2

Query: 125 LLAPATI-RSRRISQFAPLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRR 301
           + AP  + +S R+     +LI  VGLPARGK+ ++  L R+L W G  T+V+   +YRR+
Sbjct: 1   MAAPLYVTQSGRLWHAGLILIVTVGLPARGKTHISRALERYLRWLGVKTRVYSIGDYRRK 60

Query: 302 HM--ALYGSHDIFRAD---NQQGSAIRRQSAHEAVQDAVIWLKDGNSVAIFDVTNITREQ 466
            +  A    HD F+     ++  +A+RR+   E     + +   G  V I+D  N +  +
Sbjct: 61  VLGGAHNVPHDYFQTKTPRSEATNALRRRIKAELEDQIMDFFTQGGQVVIYDANNGSVAE 120

Query: 467 RRELSDYCLSDMGFRILFIECVCEDQELLERNI 565
           R+  S+    + G  ++++E +C+ ++++  NI
Sbjct: 121 RKITSEK-FGNRGVHVIYLESLCDQEDIITANI 152


>UniRef50_Q6BT67 Cluster: Similar to CA2215|CaPFK26 Candida albicans
           CaPFK26 6-phosphofructose- 2-kinase; n=3;
           Saccharomycetaceae|Rep: Similar to CA2215|CaPFK26
           Candida albicans CaPFK26 6-phosphofructose- 2-kinase -
           Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
          Length = 938

 Score = 48.8 bits (111), Expect(2) = 5e-13
 Identities = 26/83 (31%), Positives = 47/83 (56%), Gaps = 3/83 (3%)
 Frame = +2

Query: 326 DIFRADNQQGSAIRRQSAHEAVQDAVIWLKDGN-SVAIFDVTNITREQRRELSDYCL--S 496
           D F  DN+  + +R + A + +   + ++ DG+ SV IFD TN T+++R ++       S
Sbjct: 422 DFFSPDNKSTNMLREKWAMDTLDQLLNYVIDGSGSVGIFDATNSTKKRRMKILKKIKERS 481

Query: 497 DMGFRILFIECVCEDQELLERNI 565
               ++LF+E +C D  ++E NI
Sbjct: 482 KGELKVLFLESICSDPAIIESNI 504



 Score = 47.6 bits (108), Expect(2) = 5e-13
 Identities = 20/42 (47%), Positives = 29/42 (69%)
 Frame = +2

Query: 176 LLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRR 301
           L+I +VGLPARGKS + ++L R+LNW     +VF+    RR+
Sbjct: 340 LVIVMVGLPARGKSYITNKLTRYLNWLQHDCRVFNVGNTRRK 381


>UniRef50_Q06137 Cluster: Putative
           6-phosphofructo-2-kinase/fructose-2,6-biphosphatase
           YLR345W [Includes: 6-phosphofructo-2-kinase (EC
           2.7.1.105); Fructose-2,6- bisphosphatase (EC 3.1.3.46)];
           n=3; Saccharomycetales|Rep: Putative
           6-phosphofructo-2-kinase/fructose-2,6-biphosphatase
           YLR345W [Includes: 6-phosphofructo-2-kinase (EC
           2.7.1.105); Fructose-2,6- bisphosphatase (EC 3.1.3.46)]
           - Saccharomyces cerevisiae (Baker's yeast)
          Length = 509

 Score = 76.2 bits (179), Expect = 5e-13
 Identities = 41/131 (31%), Positives = 70/131 (53%), Gaps = 1/131 (0%)
 Frame = +2

Query: 176 LLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYGSHDIFRADNQQG 355
           +L+ LVGLPA  K+ L+  + R+  W G  TK F  SEY+     +   +      +++G
Sbjct: 84  ILVVLVGLPATSKTLLSVAITRYTRWLGVRTKSFHFSEYKESAKNIPSDYFCVVPTSKEG 143

Query: 356 SAIRRQSAHEAVQDAVIWLKD-GNSVAIFDVTNITREQRRELSDYCLSDMGFRILFIECV 532
            A   +   + + D + +  D    +AI+D  NI +  R+ L +   S++G ++LFIE +
Sbjct: 144 VAFVEKLRMQMLNDILAFFNDLSGQLAIYDALNIRKIDRKNL-ETTFSEIGVKVLFIESI 202

Query: 533 CEDQELLERNI 565
             DQE++ RNI
Sbjct: 203 VSDQEIMNRNI 213


>UniRef50_Q6FWD2 Cluster: Similar to sp|P40433 Saccharomyces
           cerevisiae YIL107c 6-phosphofructo- 2-kinase 1; n=2;
           Candida glabrata|Rep: Similar to sp|P40433 Saccharomyces
           cerevisiae YIL107c 6-phosphofructo- 2-kinase 1 - Candida
           glabrata (Yeast) (Torulopsis glabrata)
          Length = 806

 Score = 74.9 bits (176), Expect = 1e-12
 Identities = 42/136 (30%), Positives = 81/136 (59%), Gaps = 6/136 (4%)
 Frame = +2

Query: 176 LLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYG----SHDIFRAD 343
           L+I +VGLPA GKS + ++L+R+LN++    +VF+    RR++    G        F   
Sbjct: 245 LVIVMVGLPATGKSFITNKLSRYLNYSMYYCQVFNVGNTRRKYAKQMGLSEQDSSFFDPT 304

Query: 344 NQQGSAIRRQSAHEAVQDAVIWLKDG-NSVAIFDVTNITREQRRELSDYCLS-DMGFRIL 517
           N + +A+R + A + +++ + +L DG  SV IFD TN ++ +R+++ +   +     ++L
Sbjct: 305 NTEYTALRDKWALDTLEELMDYLLDGPGSVGIFDATNTSKARRKQVLERIRNRSPHLKVL 364

Query: 518 FIECVCEDQELLERNI 565
           F+E +C ++ ++E NI
Sbjct: 365 FLESICTNKAVVESNI 380


>UniRef50_Q4PFU8 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 508

 Score = 73.3 bits (172), Expect = 4e-12
 Identities = 42/138 (30%), Positives = 73/138 (52%), Gaps = 8/138 (5%)
 Frame = +2

Query: 176 LLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYGSHDIFRAD---- 343
           +LIA VGLPARGK+ L+H + R+L W G  + VF   ++RR+   + G  D   AD    
Sbjct: 41  ILIATVGLPARGKTHLSHAIERYLTWLGVKSGVFSLGDHRRK---VLGGADKIPADYFST 97

Query: 344 --NQQGSAIRRQSAHEAVQDAVI--WLKDGNSVAIFDVTNITREQRRELSDYCLSDMGFR 511
               + +   R+S  +   D VI  + + G  V ++D  N  + +R  + +     +G  
Sbjct: 98  GPKSESTEKLRKSILDDFDDTVIDFFFEQGGQVVLYDANNSVQSRRYAIREK-YGKLGVH 156

Query: 512 ILFIECVCEDQELLERNI 565
           ++F+E +C D +++E N+
Sbjct: 157 VMFLESICTDPKVVEANV 174


>UniRef50_Q6C8B6 Cluster: Similar to KLLA0B05709g Kluyveromyces
           lactis IPF 7503.1; n=1; Yarrowia lipolytica|Rep: Similar
           to KLLA0B05709g Kluyveromyces lactis IPF 7503.1 -
           Yarrowia lipolytica (Candida lipolytica)
          Length = 592

 Score = 69.7 bits (163), Expect = 4e-11
 Identities = 49/141 (34%), Positives = 68/141 (48%), Gaps = 13/141 (9%)
 Frame = +2

Query: 182 IALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRR----HMALYGSHDI--FRAD 343
           I LVGLPARGK+ LA  L R+L W G  T  F   +YRR     H    G  D     +D
Sbjct: 66  IVLVGLPARGKTHLAVSLTRYLRWLGVKTHAFHLGDYRRAQFPDHETQTGKADAESLPSD 125

Query: 344 ------NQQGSAIRRQSAHEAVQDA-VIWLKDGNSVAIFDVTNITREQRRELSDYCLSDM 502
                 +++   +R Q     + D  V + K    VAI+D  N T + R++L D   +  
Sbjct: 126 YFDLNPSEKTKKLRSQIVDACLADMDVFFDKHNGQVAIYDAVNPTYQIRQDLVDKLTTRS 185

Query: 503 GFRILFIECVCEDQELLERNI 565
             ++LF+E  C D  L+ RNI
Sbjct: 186 ERQVLFVESYCTDDSLVARNI 206


>UniRef50_A3LYR6 Cluster: 6-phosphofructose-2-kinase; n=3;
           Saccharomycetales|Rep: 6-phosphofructose-2-kinase -
           Pichia stipitis (Yeast)
          Length = 892

 Score = 69.7 bits (163), Expect = 4e-11
 Identities = 46/155 (29%), Positives = 77/155 (49%), Gaps = 25/155 (16%)
 Frame = +2

Query: 176 LLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYGSH---------- 325
           L+I +VGLPARGKS + ++L R+LNW     +VF+    RR+     G            
Sbjct: 338 LVIVMVGLPARGKSYITNKLTRYLNWLQHDCRVFNVGNTRRKDKNNAGPEKKPLPDAVTP 397

Query: 326 ------------DIFRADNQQGSAIRRQSAHEAVQDAVIWLKDG-NSVAIFDVTNITREQ 466
                       D F  DN+  +A+R + A + + + + ++ DG  SV IFD TN T+ +
Sbjct: 398 TNQPSSPSQHNADFFSPDNKSSNALREKWAMDTLDNLLDYIVDGPGSVGIFDATNSTKSR 457

Query: 467 RRELSDYC--LSDMGFRILFIECVCEDQELLERNI 565
           R  +       ++   ++L++E +C D  ++E NI
Sbjct: 458 RLHVLKRINERTNGELKVLYLESICSDPAIIESNI 492


>UniRef50_Q17A04 Cluster: 6-phosphofructo-2-kinase/fructose-2,
           6-bisphosphatase; n=2; Culicidae|Rep:
           6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase -
           Aedes aegypti (Yellowfever mosquito)
          Length = 458

 Score = 68.9 bits (161), Expect = 8e-11
 Identities = 46/129 (35%), Positives = 68/129 (52%)
 Frame = +2

Query: 170 APLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYGSHDIFRADNQ 349
           APL++  VGLP RGKS  +H++ARHL+W GES KVF                      N 
Sbjct: 39  APLVVTTVGLPCRGKSLASHKVARHLSWRGESAKVF----------------------NV 76

Query: 350 QGSAIRRQSAHEAVQDAVIWLKDGNSVAIFDVTNITREQRRELSDYCLSDMGFRILFIEC 529
            G+A       + +++   + K+GN+VAI D  ++TR+ R+ L ++C  +  +  L IE 
Sbjct: 77  DGNA-----TADTLREISAFFKEGNNVAIIDGMHLTRQSRQLLINFC-GEQLYHHLLIEF 130

Query: 530 VCEDQELLE 556
            C DQ L E
Sbjct: 131 SCNDQCLRE 139


>UniRef50_A0BXN8 Cluster: Chromosome undetermined scaffold_135,
           whole genome shotgun sequence; n=2; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_135,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 414

 Score = 68.9 bits (161), Expect = 8e-11
 Identities = 36/135 (26%), Positives = 74/135 (54%), Gaps = 5/135 (3%)
 Frame = +2

Query: 176 LLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYGSHDI---FRADN 346
           L++ LVGLPARGK+ + ++L R+LNW G  +++F     ++ +  L  + D       +N
Sbjct: 11  LILVLVGLPARGKTHITYKLNRYLNWIGYKSEIFSIKGAQQNNDQLDQNIDYELEIDPNN 70

Query: 347 QQGSAIRRQSAHEAVQDAVIWLKDGNSVAIFDVTNITREQRRELSDYCLS--DMGFRILF 520
            Q + +R+  +  A Q  V +L+    +A+++    T+  R++L  +      + ++  +
Sbjct: 71  PQFAEVRQHLSTTAAQQLVAFLQSDGDIALYNGLTSTKADRQKLKSFFKETLKLEYQTFW 130

Query: 521 IECVCEDQELLERNI 565
           IE +C+D +++  NI
Sbjct: 131 IESICDDPQVILNNI 145


>UniRef50_Q6BVZ2 Cluster: Debaryomyces hansenii chromosome B of
           strain CBS767 of Debaryomyces hansenii; n=1;
           Debaryomyces hansenii|Rep: Debaryomyces hansenii
           chromosome B of strain CBS767 of Debaryomyces hansenii -
           Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
          Length = 360

 Score = 64.9 bits (151), Expect = 1e-09
 Identities = 43/147 (29%), Positives = 74/147 (50%), Gaps = 5/147 (3%)
 Frame = +2

Query: 140 TIRSRRISQFAPLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRR--HMAL 313
           T+ S++++ F   +I LVGLPA GKS ++ +L  + +     +K+++  + RRR  H + 
Sbjct: 94  TLISKKLN-FNKTIIILVGLPASGKSTISKQLCSYFDQKNFKSKIYNAGDIRRRLKHNS- 151

Query: 314 YGSHDIFRADNQQGSAIRRQSAHEAVQDAVIWLKDGN-SVAIFDVTNITREQRRELSDYC 490
           + S D F  +N +    R   A  ++   +  L  GN SV   D TN T E+R ++  Y 
Sbjct: 152 FNSSDFFDPNNLKAKHEREVFATTSLSTLIHDLNQGNISVGFLDATNTTLERRNKIMQYI 211

Query: 491 --LSDMGFRILFIECVCEDQELLERNI 565
                    ++ ++  C DQ L+  NI
Sbjct: 212 RETPTRADNVILMDIQCNDQTLINFNI 238


>UniRef50_A7TP12 Cluster: Putative uncharacterized protein; n=1;
           Vanderwaltozyma polyspora DSM 70294|Rep: Putative
           uncharacterized protein - Vanderwaltozyma polyspora DSM
           70294
          Length = 502

 Score = 64.9 bits (151), Expect = 1e-09
 Identities = 37/142 (26%), Positives = 72/142 (50%), Gaps = 1/142 (0%)
 Frame = +2

Query: 146 RSRRISQFAPLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYGSH 325
           +S ++     ++I LVGLPA  K+ L+  ++R+  W G  T+ F  SEYR+    +   +
Sbjct: 77  QSGKLFHAGKIMIVLVGLPASSKTLLSVAISRYSRWLGVRTESFHASEYRKDKEHIPDDY 136

Query: 326 DIFRADNQQGSAIRRQSAHEAVQDAVIWLKDGN-SVAIFDVTNITREQRRELSDYCLSDM 502
                  Q+G   +             + ++ N  +AI+D  NI R  R+ + +   S +
Sbjct: 137 YSAVPQTQEGRDFKTNIIESTYNAMANFYQNLNGQLAIYDALNIRRSDRKNI-ETVFSKL 195

Query: 503 GFRILFIECVCEDQELLERNII 568
             ++LFIE +  +++L+++NI+
Sbjct: 196 NVKVLFIESIINNEQLMKQNIM 217


>UniRef50_Q75CV1 Cluster: ACL185Cp; n=2; Saccharomycetaceae|Rep:
           ACL185Cp - Ashbya gossypii (Yeast) (Eremothecium
           gossypii)
          Length = 566

 Score = 62.1 bits (144), Expect = 9e-09
 Identities = 44/144 (30%), Positives = 71/144 (49%), Gaps = 5/144 (3%)
 Frame = +2

Query: 149 SRRISQFAPLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHM---ALYG 319
           S R+     +LI LVGLPA  K+ ++  + R+  W G  T+ F  SEYRR  +    +  
Sbjct: 83  SGRLFHAGKILIVLVGLPATSKTLVSVAITRYTRWLGVRTQSFHVSEYRRARVPQGMVKL 142

Query: 320 SHDIF--RADNQQGSAIRRQSAHEAVQDAVIWLKDGNSVAIFDVTNITREQRRELSDYCL 493
             D F  R    +G  +RR    E   D   + + G  +A++D  NI RE+RR L++   
Sbjct: 143 PLDYFSARPVTPEGIRLRRTLIAEIQADMKKFFEQG-QLAVYDGMNIMREERRMLAEE-F 200

Query: 494 SDMGFRILFIECVCEDQELLERNI 565
           + +  ++ F+E V  +  L  R +
Sbjct: 201 AALNVKVFFVESVVSESILRARTV 224


>UniRef50_Q59WJ3 Cluster: Putative uncharacterized protein; n=1;
           Candida albicans|Rep: Putative uncharacterized protein -
           Candida albicans (Yeast)
          Length = 361

 Score = 62.1 bits (144), Expect = 9e-09
 Identities = 41/134 (30%), Positives = 67/134 (50%), Gaps = 4/134 (2%)
 Frame = +2

Query: 176 LLIALVGLPARGKSQLAHRLARHLNWNGE-STKVFDCSEYRRRHMAL-YGSHDIFRADNQ 349
           L++ LVGLPA GKS +  +    +N N E + ++++  + RRR  A  +     F  +N+
Sbjct: 133 LILLLVGLPASGKSTICKQFQEFINENSEYNAQIYNAGDVRRRRSASEFNDAQFFDPNNE 192

Query: 350 QGSAIRRQSAHEAVQDAVIWLKDG-NSVAIFDVTNITREQRRELSDYCLSDM-GFRILFI 523
           QG   R   A   V + +  L+     V   D TN T E+R+ + +     +   RI+  
Sbjct: 193 QGKKDRELYATITVNNLINDLQSNVIDVGFLDATNTTLERRQRMINLINEQVPNGRIVIF 252

Query: 524 ECVCEDQELLERNI 565
           +  C +Q+LLE NI
Sbjct: 253 DVQCNNQKLLEYNI 266


>UniRef50_Q4Q9G0 Cluster:
           6-phosphofructo-2-kinase/fructose-2,6-biphospha ta
           se1-like protein; n=7; Trypanosomatidae|Rep:
           6-phosphofructo-2-kinase/fructose-2,6-biphospha ta
           se1-like protein - Leishmania major
          Length = 667

 Score = 61.7 bits (143), Expect = 1e-08
 Identities = 40/138 (28%), Positives = 68/138 (49%), Gaps = 7/138 (5%)
 Frame = +2

Query: 176 LLIALVGLPARGKSQLAHRLARHLNWNGESTKVF---DCSEYRRRHMALYGSHDIFRADN 346
           L++ +VGLP RGK+ +A ++ R+  WNG + K+F    C     R M      D   +  
Sbjct: 220 LIVIMVGLPGRGKTYVAEQIRRYFQWNGLTCKIFFHQACRRRVERAMTDRADRDADVSSP 279

Query: 347 QQGSAIRRQSAHEAVQDAVIWLKDGNSVAIFDVTNITREQR----RELSDYCLSDMGFRI 514
              + +  + + E   D   ++   + VAI D T  T  +R    R + D  L +M  R+
Sbjct: 280 TGATELEFRISKELAHDLTTYVCKTSGVAILDGTQTTHARRQYLLRAIRDTRLINM-TRV 338

Query: 515 LFIECVCEDQELLERNII 568
           +F+E V  ++E + RNI+
Sbjct: 339 VFVELVNNNKETIHRNIL 356


>UniRef50_A3GFN4 Cluster: 6-phosphofructo-2-kinase; n=2; Pichia
           stipitis|Rep: 6-phosphofructo-2-kinase - Pichia stipitis
           (Yeast)
          Length = 374

 Score = 58.8 bits (136), Expect = 8e-08
 Identities = 36/116 (31%), Positives = 59/116 (50%), Gaps = 2/116 (1%)
 Frame = +2

Query: 143 IRSRRISQFAPLLIALVGLPARGKSQLAHRLARHLNWNGEST-KVFDCSEYRRRHMALYG 319
           +  + ISQ   L+I L GLPA GKS ++ +L  ++N     T ++++    RR + + + 
Sbjct: 119 VNEKLISQHEKLVIMLSGLPASGKSTISRQLKNYINATSNFTAEIYNAGNVRRMNKS-FD 177

Query: 320 SHDIFRADNQQGSAIRRQSAHEAVQDAVIWLKDG-NSVAIFDVTNITREQRRELSD 484
           + D F+ DN QG   R + A   V + +  L      V   D TN T E+R+ + D
Sbjct: 178 NSDYFKPDNVQGKIDREKYADITVNNLINDLNSNVIQVGFLDATNTTIERRKRMMD 233


>UniRef50_A5DTU6 Cluster: Putative uncharacterized protein; n=1;
           Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
           uncharacterized protein - Lodderomyces elongisporus
           (Yeast) (Saccharomyces elongisporus)
          Length = 453

 Score = 56.4 bits (130), Expect = 4e-07
 Identities = 34/142 (23%), Positives = 73/142 (51%), Gaps = 12/142 (8%)
 Frame = +2

Query: 176 LLIALVGLPARGKSQLAHRLARHL-NWNGESTKVFDCSEYRRR-HMALYGSHDIFRADNQ 349
           L++ LVGLPA GKS L H+L  ++ N+   ++++++  + RRR  + ++     F   N+
Sbjct: 187 LVVLLVGLPASGKSTLCHQLNSYINNYTQYTSRIYNAGDVRRRKSLGIFNDSRFFDPKNK 246

Query: 350 QGSAIRRQSAHEAVQDAVIWL------KDGNSVAIFDVTNITREQRRELSDYC----LSD 499
           +    R   A  A+ + +  +      K+   +  FD TN T+++R+ + +        +
Sbjct: 247 EARQDRELYASIAISNLIKDITSPPQNKNSIDIGFFDATNTTKDRRQRMLETIHTNNTQN 306

Query: 500 MGFRILFIECVCEDQELLERNI 565
           +  R + ++  C +Q +++ NI
Sbjct: 307 VQLRTVILDVQCNNQHMIDYNI 328


>UniRef50_A5DGB7 Cluster: Putative uncharacterized protein; n=1;
           Pichia guilliermondii|Rep: Putative uncharacterized
           protein - Pichia guilliermondii (Yeast) (Candida
           guilliermondii)
          Length = 301

 Score = 56.4 bits (130), Expect = 4e-07
 Identities = 37/131 (28%), Positives = 65/131 (49%), Gaps = 2/131 (1%)
 Frame = +2

Query: 179 LIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYGSHDIFRADNQQGS 358
           ++ LVGLPA GKS +A +L+R L  +G    +F+  + RR+      + + F  DN    
Sbjct: 69  VVMLVGLPASGKSTIARQLSRFLQKSGYKCDIFNAGDVRRKMHQQLSTSEFFDPDNVTAK 128

Query: 359 AIRRQSAHEAVQDAVIWLKDG-NSVAIFDVTNITREQRRELSDYC-LSDMGFRILFIECV 532
             R   A  A+ D +  L+D   +V   D TN + E+R+ + +    + +    + ++  
Sbjct: 129 RQRDTFATMAMTDLLSNLQDEVINVGFLDATNTSIERRKSMIEMSRQAGIVDHFIILDVA 188

Query: 533 CEDQELLERNI 565
           C+ +E L  NI
Sbjct: 189 CDIEEYLLFNI 199


>UniRef50_Q4VBA9 Cluster: PFKFB1 protein; n=6; Eutheria|Rep: PFKFB1
           protein - Homo sapiens (Human)
          Length = 271

 Score = 56.0 bits (129), Expect = 6e-07
 Identities = 40/111 (36%), Positives = 57/111 (51%), Gaps = 3/111 (2%)
 Frame = +2

Query: 146 RSRRISQF--APLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYG 319
           R   I QF  +P ++ +VGLPARGK+ ++ +L R+LNW G  TK                
Sbjct: 31  RGSSIPQFTNSPTMVIMVGLPARGKTYISTKLTRYLNWIGTPTK---------------- 74

Query: 320 SHDIFRADNQQGSAIRRQSAHEAVQDAVIWLK-DGNSVAIFDVTNITREQR 469
                  DN +   IR+Q A  A++D   +L  +   VA+FD TN TRE+R
Sbjct: 75  -------DNMEALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTRERR 118


>UniRef50_Q6CVK4 Cluster: Kluyveromyces lactis strain NRRL Y-1140
           chromosome B of strain NRRL Y- 1140 of Kluyveromyces
           lactis; n=1; Kluyveromyces lactis|Rep: Kluyveromyces
           lactis strain NRRL Y-1140 chromosome B of strain NRRL Y-
           1140 of Kluyveromyces lactis - Kluyveromyces lactis
           (Yeast) (Candida sphaerica)
          Length = 272

 Score = 56.0 bits (129), Expect = 6e-07
 Identities = 37/136 (27%), Positives = 73/136 (53%), Gaps = 7/136 (5%)
 Frame = +2

Query: 179 LIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRR---HMALYGSHDIFRADNQ 349
           +I +VGLPARGKS +A ++   ++ N    ++F+  + RR+         +  +F   + 
Sbjct: 19  VIVMVGLPARGKSTIAKQIESTISGN---CRIFNAGQRRRQLENDANSLPNDQLFDMSDP 75

Query: 350 QGSAIRRQSAHEAVQDAVIWLKD--GNSVAIFDVTNITREQRRELSDYC--LSDMGFRIL 517
                R + A ++++D + WL+    N V IFD TN T ++R  + D     S++  R++
Sbjct: 76  LSVKSRDEIALKSLKDLLSWLQADYDNHVGIFDATNSTIKRRNLILDTLQEYSNVPIRVV 135

Query: 518 FIECVCEDQELLERNI 565
           FIE + + + ++E ++
Sbjct: 136 FIEVIVDSEHIIEEHL 151


>UniRef50_A7EQN2 Cluster: Putative uncharacterized protein; n=1;
           Sclerotinia sclerotiorum 1980|Rep: Putative
           uncharacterized protein - Sclerotinia sclerotiorum 1980
          Length = 695

 Score = 53.2 bits (122), Expect = 4e-06
 Identities = 33/84 (39%), Positives = 49/84 (58%), Gaps = 2/84 (2%)
 Frame = +2

Query: 320 SHDIFRADNQQGSAIRRQSAHEAVQDAVIWLKDGN-SVAIFDVTNITREQRRELSDYCLS 496
           S + F   N + +AIR Q A + + + + +L  G+ +V I D TN T E+RR L ++   
Sbjct: 294 SANFFDPMNSKAAAIREQVAMDTLDELLDFLLLGSGAVGILDATNSTIERRRHLFNHVKE 353

Query: 497 -DMGFRILFIECVCEDQELLERNI 565
            +    ILFIE VCED+ LLE N+
Sbjct: 354 REPKLGILFIESVCEDESLLEANM 377



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 17/41 (41%), Positives = 28/41 (68%)
 Frame = +2

Query: 176 LLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRR 298
           L++ +VGLPARGKS +  ++ R+L+W    T++F+    RR
Sbjct: 169 LVVIMVGLPARGKSYITKKIQRYLSWQQHETRIFNVGNRRR 209


>UniRef50_Q0URN0 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 406

 Score = 52.8 bits (121), Expect = 5e-06
 Identities = 26/61 (42%), Positives = 37/61 (60%)
 Frame = +2

Query: 116 KEKLLAPATIRSRRISQFAPLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYR 295
           K K+     I  R +   + L+I +VGLPARGKS +  ++AR+LNW    TK+F+  E R
Sbjct: 191 KSKVSPDGKIAQRDVG--SKLVIVMVGLPARGKSYITKKMARYLNWLQHDTKIFNVGEKR 248

Query: 296 R 298
           R
Sbjct: 249 R 249


>UniRef50_A1CQU3 Cluster: 6-phosphofructo-2-kinase 1; n=7;
           Eurotiomycetidae|Rep: 6-phosphofructo-2-kinase 1 -
           Aspergillus clavatus
          Length = 709

 Score = 52.4 bits (120), Expect = 7e-06
 Identities = 35/96 (36%), Positives = 52/96 (54%)
 Frame = +2

Query: 116 KEKLLAPATIRSRRISQFAPLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYR 295
           K K+     I  R +   + L+I +VGLPARGKS +  +LAR+LNW    T++F+  E  
Sbjct: 119 KSKVSPDGRIAQRDLG--SKLVIVMVGLPARGKSYVTKKLARYLNWLQHDTEIFNVGE-- 174

Query: 296 RRHMALYGSHDIFRADNQQGSAIRRQSAHEAVQDAV 403
           RR +A   S    RA        +R+S H+ + D+V
Sbjct: 175 RRRVAAGKSPSPARA---MAPRDKRESMHKDLVDSV 207



 Score = 45.6 bits (103), Expect = 8e-04
 Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 3/85 (3%)
 Frame = +2

Query: 320 SHDIFRADNQQGSAIRRQSAHEAVQDAVIW-LKDGNSVAIFDVTNITREQRRELSDYCLS 496
           S   F   NQ+   +R Q A + + + + + L  G SV I D TN T E+R+ + D+   
Sbjct: 295 SASFFDPQNQRAVKLREQVALDTLDELLDYILVRGGSVGILDATNSTLERRKLIVDHVRK 354

Query: 497 DMG--FRILFIECVCEDQELLERNI 565
             G    +LF+E  C D  LLE N+
Sbjct: 355 IAGPELGVLFLESSCMDPALLEANM 379


>UniRef50_Q1E4N6 Cluster: 6-phosphofructo-2-kinase; n=1;
           Coccidioides immitis|Rep: 6-phosphofructo-2-kinase -
           Coccidioides immitis
          Length = 705

 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 33/102 (32%), Positives = 52/102 (50%), Gaps = 3/102 (2%)
 Frame = +2

Query: 2   NATVSSHETRSGFSEKTLVQENSNGARDLARATAMMEDKEKLLAPATIRSRRISQF---A 172
           NA   +  + +  S + + +  S+GA    +  A   D   L         RI+Q    +
Sbjct: 34  NALTDTPVSTAPPSPQIIPRSYSSGASTPGKIRATTLDIPGLTKSKVSPDGRIAQRDVGS 93

Query: 173 PLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRR 298
            L+I +VGLPARGKS +  +L+R+LNW    T++F+  E RR
Sbjct: 94  KLVIVMVGLPARGKSYITKKLSRYLNWLQHDTRIFNVGERRR 135



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 26/82 (31%), Positives = 46/82 (56%), Gaps = 3/82 (3%)
 Frame = +2

Query: 332 FRADNQQGSAIRRQSAHEAVQDAVIWLKD-GNSVAIFDVTNITREQRRELSDYCLSDMG- 505
           F   N++   +R + A E + + + ++ D G SV I D TN T ++R+ + ++  +  G 
Sbjct: 293 FDPKNERALQLRERVALETLDELLDYILDQGGSVGILDATNSTIKRRKTIMEHIRAKAGP 352

Query: 506 -FRILFIECVCEDQELLERNII 568
              +LF+E  C DQ LLE N++
Sbjct: 353 ALNVLFVESQCLDQNLLESNML 374


>UniRef50_A6RRU2 Cluster: Putative uncharacterized protein; n=1;
           Botryotinia fuckeliana B05.10|Rep: Putative
           uncharacterized protein - Botryotinia fuckeliana B05.10
          Length = 672

 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 33/84 (39%), Positives = 47/84 (55%), Gaps = 2/84 (2%)
 Frame = +2

Query: 320 SHDIFRADNQQGSAIRRQSAHEAVQDAVIWLKDGN-SVAIFDVTNITREQRRELSDYC-L 493
           S + F   N + + IR Q A   + + + +L  GN +V I D TN T E+R+ L D+   
Sbjct: 254 SANFFDPLNSKAALIREQVAMATLDELLDFLLLGNGAVGILDATNSTIERRKLLFDHVKF 313

Query: 494 SDMGFRILFIECVCEDQELLERNI 565
            +    ILFIE VCED+ LLE N+
Sbjct: 314 REPKLGILFIESVCEDESLLEANM 337



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 17/41 (41%), Positives = 28/41 (68%)
 Frame = +2

Query: 176 LLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRR 298
           L++ +VGLPARGKS +  ++ R+L+W    T++F+    RR
Sbjct: 134 LVVIMVGLPARGKSYITKKIQRYLSWQQHETRIFNVGNRRR 174


>UniRef50_Q9URZ7 Cluster: 6-phosphofructo-2-kinase; n=1;
           Schizosaccharomyces pombe|Rep: 6-phosphofructo-2-kinase
           - Schizosaccharomyces pombe (Fission yeast)
          Length = 408

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 33/130 (25%), Positives = 59/130 (45%)
 Frame = +2

Query: 176 LLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYGSHDIFRADNQQG 355
           L +  VGLPA GK+  A +L+R+L W   ST ++D  E           + +    N   
Sbjct: 10  LCVCFVGLPASGKTSSAMKLSRYLTWMSVSTHLYDTKEI---------DNSLSENSNSDS 60

Query: 356 SAIRRQSAHEAVQDAVIWLKDGNSVAIFDVTNITREQRRELSDYCLSDMGFRILFIECVC 535
             + + +      +     K G  VAI D    T + R+ + +   +     ++F+E VC
Sbjct: 61  ENLAK-TLSPIFDNLESVFKKGTDVAILDFNQCTLKFRKSIVELAKA-RNMLLMFVEVVC 118

Query: 536 EDQELLERNI 565
            +Q++++ NI
Sbjct: 119 TNQKIIDENI 128


>UniRef50_Q1E494 Cluster: Putative uncharacterized protein; n=1;
           Coccidioides immitis|Rep: Putative uncharacterized
           protein - Coccidioides immitis
          Length = 457

 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 26/67 (38%), Positives = 41/67 (61%), Gaps = 3/67 (4%)
 Frame = +2

Query: 107 MEDKEKLLAPATI---RSRRISQFAPLLIALVGLPARGKSQLAHRLARHLNWNGESTKVF 277
           + DK ++ APA +    S R+     ++I  VGLPARGK+ ++  +AR+L W G  T++F
Sbjct: 30  LPDKPEI-APAQLYSTESGRLFHSGRIVIITVGLPARGKTHISVAIARYLRWLGVKTRIF 88

Query: 278 DCSEYRR 298
              +YRR
Sbjct: 89  HLGDYRR 95


>UniRef50_Q9P522 Cluster: Related to 6-phosphofructo-2-kinase; n=4;
           Sordariomycetes|Rep: Related to 6-phosphofructo-2-kinase
           - Neurospora crassa
          Length = 804

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 19/43 (44%), Positives = 30/43 (69%)
 Frame = +2

Query: 170 APLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRR 298
           A L++ +VGLPARGKS +  ++ R+L+W   +TK+F+    RR
Sbjct: 273 AKLVVIMVGLPARGKSYITKKIQRYLSWQQHNTKIFNVGNRRR 315



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 28/84 (33%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
 Frame = +2

Query: 320 SHDIFRADNQQGSAIRRQSAHEAVQDAVIWL-KDGNSVAIFDVTNITREQRRELSDYCLS 496
           S   F   N+  + +R Q A + + + + +L   G SV I D TN    +R+ L ++   
Sbjct: 388 SAKFFDPKNEIAAKLREQVAIDTLDELLNYLLHQGGSVGILDATNSNVHRRKLLVEHIQQ 447

Query: 497 -DMGFRILFIECVCEDQELLERNI 565
            +    ILFIE +C DQ LLE N+
Sbjct: 448 REPKLGILFIESICHDQNLLEANM 471


>UniRef50_Q57VQ2 Cluster: 6-phosphofructo-2-kinase/fructose-2,
           6-biphosphatase, putative; n=2; Trypanosoma brucei|Rep:
           6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase,
           putative - Trypanosoma brucei
          Length = 702

 Score = 46.4 bits (105), Expect = 5e-04
 Identities = 27/75 (36%), Positives = 39/75 (52%), Gaps = 2/75 (2%)
 Frame = +2

Query: 134 PATIRSRRISQFAPLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCS-EYRRRHMA 310
           P     +  S    L + +VGLPARGK+ LAH++ R L W+G   KV +    +RR  M 
Sbjct: 174 PVHFDDKTHSYTTTLCVIMVGLPARGKTFLAHKVCRLLGWHGHRAKVLNVQVAWRRLLMN 233

Query: 311 LY-GSHDIFRADNQQ 352
            Y G  D  R++  +
Sbjct: 234 YYNGQGDESRSERSR 248


>UniRef50_Q4DA36 Cluster: 6-phosphofructo-2-kinase/fructose-2,
           6-biphosphatase, putative; n=2; Trypanosoma cruzi|Rep:
           6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase,
           putative - Trypanosoma cruzi
          Length = 749

 Score = 46.0 bits (104), Expect = 6e-04
 Identities = 23/49 (46%), Positives = 30/49 (61%)
 Frame = +2

Query: 170 APLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALY 316
           A L I +VGLPARGK+ LA R+ R+L W+G   KV +     RR +  Y
Sbjct: 187 ASLCIIMVGLPARGKTFLAQRICRNLGWHGYRAKVLNIQVAWRRLLLEY 235


>UniRef50_A7THC8 Cluster: Putative uncharacterized protein; n=1;
           Vanderwaltozyma polyspora DSM 70294|Rep: Putative
           uncharacterized protein - Vanderwaltozyma polyspora DSM
           70294
          Length = 394

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 43/147 (29%), Positives = 70/147 (47%), Gaps = 21/147 (14%)
 Frame = +2

Query: 188 LVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYR----RRHMALYG---------SHD 328
           L+GLPA GKS ++  L ++ N N +STK   CS Y     RR+++  G         S D
Sbjct: 91  LIGLPASGKSSISSHLIKYFNSN-DSTKHLRCSIYNAGQVRRNLSNNGLPMKLANDSSED 149

Query: 329 IFRADN-QQGSAIRRQSAHEAVQDAVIWLKDGNSVAIFDVTNITREQRR----ELSDYCL 493
           +F   N  +     + + +  ++D      D   +AIFD TN T+ +R+    E S Y  
Sbjct: 150 LFNPKNSNKKEKFAKITLNNLLRDV---NNDACDIAIFDATNSTKARRKFLISEFSYYNS 206

Query: 494 S-DMGFRI--LFIECVCEDQELLERNI 565
           + +  F I  +F++  C D   +  N+
Sbjct: 207 NVNSSFHIIPIFLQISCNDINFIRYNV 233


>UniRef50_Q8X0M5 Cluster: Related to
           6-phosphofructo-2-kinase/fructose-2, 6-bisphosphate 2-
           phosphatase; n=5; Pezizomycotina|Rep: Related to
           6-phosphofructo-2-kinase/fructose-2, 6-bisphosphate 2-
           phosphatase - Neurospora crassa
          Length = 528

 Score = 44.8 bits (101), Expect = 0.001
 Identities = 44/153 (28%), Positives = 69/153 (45%), Gaps = 8/153 (5%)
 Frame = +2

Query: 128 LAPATIRSR---RISQFAPLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRR 298
           +APA + S    R+     + I +VGLPARGK+             G  T++F   +YRR
Sbjct: 36  MAPAQLYSTMSGRLFHSGRIAIVMVGLPARGKTL------------GVKTRIFHLGDYRR 83

Query: 299 RHMALYGS--HDIFRADNQQGSAIRRQS-AHEAVQDAVIWLKDGN-SVAIFDVTNITREQ 466
             +   G+   D F  +    S + RQ    +  +D   WL   N  VAI+D  N T   
Sbjct: 84  ATVGEGGNVPQDYFYPNASPASTMLRQKILKKCREDIYAWLNHENGQVAIYDAVNPTAAG 143

Query: 467 RRELS-DYCLSDMGFRILFIECVCEDQELLERN 562
           RR L+ ++   D       ++   +D+E+L+ N
Sbjct: 144 RRALAKEFAKHD-------VQSYVDDEEILKEN 169


>UniRef50_A7EUT1 Cluster: Putative uncharacterized protein; n=1;
           Sclerotinia sclerotiorum 1980|Rep: Putative
           uncharacterized protein - Sclerotinia sclerotiorum 1980
          Length = 531

 Score = 43.6 bits (98), Expect = 0.003
 Identities = 43/142 (30%), Positives = 62/142 (43%), Gaps = 8/142 (5%)
 Frame = +2

Query: 107 MEDKEKLLAPATI---RSRRISQFAPLLIALVGLPARGKSQLAHRLARHLNWNGESTKVF 277
           + D++  LAPA +    S R+     + I LVGLPARGK+             G  T++F
Sbjct: 43  LPDEKATLAPAQLYSTESGRLFHSGRIAIVLVGLPARGKTL------------GVKTRIF 90

Query: 278 DCSEYRRRHMALYGS--HDIFRADNQQGSAIRRQS-AHEAVQDAVIWLKDGN-SVAIFDV 445
              +YRR  M        D F  +    S + RQ    +  +D   WL   N  VAI+D 
Sbjct: 91  HLGDYRRATMGPGQDVPDDYFFINASAASVMLRQKILKKCREDIYAWLNHENGQVAIYDA 150

Query: 446 TNITREQRRELS-DYCLSDMGF 508
            N     RR L+ ++   D+ F
Sbjct: 151 VNPLSGGRRSLAKEFAKHDVQF 172


>UniRef50_Q4QIL3 Cluster: 6-phosphofructo-2-kinase-like protein;
           n=3; Leishmania|Rep: 6-phosphofructo-2-kinase-like
           protein - Leishmania major
          Length = 1241

 Score = 40.7 bits (91), Expect = 0.023
 Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
 Frame = +2

Query: 176 LLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCS-EYRRRHMALYGSHDIFRADNQQ 352
           L+I ++GLPARGK+ LA ++ R L W+G   K+ +    +RR  +    +H    A +  
Sbjct: 428 LIIVMMGLPARGKTFLAQKICRLLRWHGSRAKMQNIQVAWRRMLLDWEAAHPEMAACSAH 487

Query: 353 GSAIRRQSAHEAVQDA 400
             A   + A E  Q+A
Sbjct: 488 AEA---EQAEEQEQEA 500


>UniRef50_Q75AV3 Cluster: ADL183Cp; n=1; Eremothecium gossypii|Rep:
           ADL183Cp - Ashbya gossypii (Yeast) (Eremothecium
           gossypii)
          Length = 396

 Score = 40.7 bits (91), Expect = 0.023
 Identities = 43/148 (29%), Positives = 65/148 (43%), Gaps = 19/148 (12%)
 Frame = +2

Query: 179 LIALVGLPARGKSQLAHRLARHLNWNGESTK----VFDCSEYRR------RHMALYGS-- 322
           L+ LVGLPA GKS ++  L R L  N   +     VF+  + RR      R M L  S  
Sbjct: 86  LVVLVGLPAVGKSTISGHLIRFLQNNPRLSHLRCGVFNAGQVRRDLTYSGRSMKLANSSG 145

Query: 323 HDIFRADNQQGSAIRRQSAHEAVQDAVIWLKDGNSVAIFDVTNITREQRR----ELSDYC 490
            D+F   N     +  +   E +   +    D   +AIFD TN T  +RR    ++ +Y 
Sbjct: 146 EDLFNPKNSDKKNMYARITLERLFRELD--ADRCDIAIFDATNSTISRRRFIFQQVHEYN 203

Query: 491 L---SDMGFRILFIECVCEDQELLERNI 565
               SD+    + ++  C D+  +  NI
Sbjct: 204 TRLGSDINITPIVLQVTCNDENFIRFNI 231


>UniRef50_Q73Y75 Cluster: Putative uncharacterized protein; n=1;
           Mycobacterium avium subsp. paratuberculosis|Rep:
           Putative uncharacterized protein - Mycobacterium
           paratuberculosis
          Length = 479

 Score = 39.1 bits (87), Expect = 0.072
 Identities = 39/134 (29%), Positives = 59/134 (44%), Gaps = 5/134 (3%)
 Frame = +2

Query: 173 PLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYGSHDIFRADNQQ 352
           PL++  +GLPA GK+ LA  LA      G    V   S+  R+ MA  G     R  ++ 
Sbjct: 294 PLMVVTMGLPASGKTTLARALA------GRLGLVHLSSDVARKRMA--GIPPTRRGSDEF 345

Query: 353 GS-----AIRRQSAHEAVQDAVIWLKDGNSVAIFDVTNITREQRRELSDYCLSDMGFRIL 517
           GS     A+ R +     +DA  WL+ G  V + D T     +R +L       +G  + 
Sbjct: 346 GSGLYDPAMTRNTYAALRRDAARWLRRGRGVVV-DATFGNPGERAQLRQLA-HRLGVDLH 403

Query: 518 FIECVCEDQELLER 559
            + C  +D  L+ R
Sbjct: 404 VVLCDADDDTLIAR 417


>UniRef50_A0LQR4 Cluster: Putative uncharacterized protein; n=1;
           Syntrophobacter fumaroxidans MPOB|Rep: Putative
           uncharacterized protein - Syntrophobacter fumaroxidans
           (strain DSM 10017 / MPOB)
          Length = 529

 Score = 39.1 bits (87), Expect = 0.072
 Identities = 46/157 (29%), Positives = 66/157 (42%)
 Frame = +2

Query: 89  ARATAMMEDKEKLLAPATIRSRRISQFAPLLIALVGLPARGKSQLAHRLARHLNWNGEST 268
           A A A++   E+L     IR  R     P L    GLPA GK+ LA  ++  L     S+
Sbjct: 319 ANAAALVRTYEELAYRYAIRFSR-----PTLWVFCGLPATGKTSLAAAVSGPLRLRRFSS 373

Query: 269 KVFDCSEYRRRHMALYGSHDIFRADNQQGSAIRRQSAHEAVQDAVIWLKDGNSVAIFDVT 448
                      H+  YG   I+R +  +G    R  A    QD    LK G+SV I D T
Sbjct: 374 DSVRKQTIPGEHVVPYG-QGIYRPE-MRGRVYSRLLA--LAQDQ---LKSGHSV-ILDAT 425

Query: 449 NITREQRRELSDYCLSDMGFRILFIECVCEDQELLER 559
              R  R E +     D+   ++F+EC    + + +R
Sbjct: 426 FGERHWRDEAARLA-RDLDANLVFVECAARMESIRDR 461


>UniRef50_A3YZI7 Cluster: Putative uncharacterized protein; n=1;
           Synechococcus sp. WH 5701|Rep: Putative uncharacterized
           protein - Synechococcus sp. WH 5701
          Length = 565

 Score = 37.1 bits (82), Expect = 0.29
 Identities = 37/133 (27%), Positives = 58/133 (43%), Gaps = 4/133 (3%)
 Frame = +2

Query: 173 PLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYGSHDIFRADNQQ 352
           P L+ L G+   GKS LA RLA  L    + + +      R+R   LYG   + R   QQ
Sbjct: 371 PALVLLHGVSGSGKSHLAARLAPWLLAEHQRSDLI-----RKR---LYGLSPLQRPSAQQ 422

Query: 353 GSAIRRQSAHEAVQDAVIWLKDGNSV----AIFDVTNITREQRRELSDYCLSDMGFRILF 520
              I    +H   +DA++   + + V     + D T++ R   RE +      +G   L 
Sbjct: 423 RRTIYSPESHSRTEDALLAAAEASLVQGQWVLLDATHL-RAASRERATQLARQLGAVPLL 481

Query: 521 IECVCEDQELLER 559
           +E   +   LL+R
Sbjct: 482 LEVRADQTLLLQR 494


>UniRef50_Q8BRU8 Cluster: Adult male aorta and vein cDNA, RIKEN
           full-length enriched library, clone:A530095I07
           product:hypothetical protein, full insert sequence; n=1;
           Mus musculus|Rep: Adult male aorta and vein cDNA, RIKEN
           full-length enriched library, clone:A530095I07
           product:hypothetical protein, full insert sequence - Mus
           musculus (Mouse)
          Length = 146

 Score = 36.7 bits (81), Expect = 0.38
 Identities = 27/89 (30%), Positives = 35/89 (39%), Gaps = 3/89 (3%)
 Frame = +1

Query: 85  SSTGHGNDGGQRETSSTRNDPLASYQSICAAPHSPGWSASSWQESAGTPT--CQTSQLEW 258
           SS   G  GG+R    +RN P +    IC   H PG S  SW  +AG      +     W
Sbjct: 33  SSVYGGGAGGERMAQGSRNQPQSFLWRICHLGHLPGLS-RSWTTAAGQSAHPARPRVPLW 91

Query: 259 RKHQSVRLQRVSSPAYGL-VRQPRHLPRG 342
            +H        S P  G+ V    H  +G
Sbjct: 92  DRHTPESADAPSVPTQGIGVAAAAHCSQG 120


>UniRef50_Q0LCD2 Cluster: Putative uncharacterized protein; n=1;
           Herpetosiphon aurantiacus ATCC 23779|Rep: Putative
           uncharacterized protein - Herpetosiphon aurantiacus ATCC
           23779
          Length = 238

 Score = 36.7 bits (81), Expect = 0.38
 Identities = 31/95 (32%), Positives = 43/95 (45%), Gaps = 3/95 (3%)
 Frame = +2

Query: 125 LLAPATIRSRRISQFAPLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRH 304
           L A A    R    F P +  ++GL  RG+S +A +  R L   G+  K    +E+RR  
Sbjct: 81  LYAGAPFDERLTIGFVPRMAEVLGL--RGRSPMADKSGRPLGMVGDLPKPVTTAEWRRLV 138

Query: 305 MALYGSHDIFRADNQQG---SAIRRQSAHEAVQDA 400
           M +YG  D    +N Q     AI  Q     VQ+A
Sbjct: 139 MDMYGGVDEVWENNVQSIRKVAIVNQITPTLVQEA 173


>UniRef50_Q6FVI9 Cluster: Similar to sp|Q12471 Saccharomyces
           cerevisiae YOL136c 6- phosphofructose-2-kinase; n=1;
           Candida glabrata|Rep: Similar to sp|Q12471 Saccharomyces
           cerevisiae YOL136c 6- phosphofructose-2-kinase - Candida
           glabrata (Yeast) (Torulopsis glabrata)
          Length = 386

 Score = 36.7 bits (81), Expect = 0.38
 Identities = 53/206 (25%), Positives = 88/206 (42%), Gaps = 26/206 (12%)
 Frame = +2

Query: 26  TRSGFSEKTLVQ---ENSNGARDLARATAMMEDKEKLLAPATIRSR--RISQFAPLLIAL 190
           T S FS K++       +   R      AM  + +  L+ A+IR    R S+    ++ L
Sbjct: 11  TNSLFSMKSISSMDISRNTTPRPSPLGAAMSTNDQSFLSLASIRREMDRESKKDKFIVIL 70

Query: 191 VGLPARGKSQLAHRLARHLNWNGES----TKVFDCSEYRRR----------HMALYGSHD 328
           VGLPA GKS ++  L + L  N  +    + V++  + RR            +A   S D
Sbjct: 71  VGLPASGKSSISSHLIQSLKNNTATAHLRSTVYNAGKVRRMLCNGEKKKSIQIANDPSED 130

Query: 329 IFRADNQQGSAIRRQSAHEAVQDAVIWLKDGNSVAIFDVTNITREQR----RELSDY-CL 493
           +F   N +   +  +   E + + +    D    AIFD TN T ++R    RE+  Y   
Sbjct: 131 LFNPANAERKEVYAKITLENLINELD--SDICDFAIFDATNSTVQRRSFVFREIYKYNDR 188

Query: 494 SDMGFRILFI--ECVCEDQELLERNI 565
               F ++ I  +  C +Q+ +  NI
Sbjct: 189 EGANFNLIPIVFQVTCSNQDFIRYNI 214


>UniRef50_Q8XUM1 Cluster: Adenylyl-sulfate kinase; n=2; Ralstonia
           solanacearum|Rep: Adenylyl-sulfate kinase - Ralstonia
           solanacearum (Pseudomonas solanacearum)
          Length = 192

 Score = 36.3 bits (80), Expect = 0.51
 Identities = 37/102 (36%), Positives = 44/102 (43%)
 Frame = +2

Query: 170 APLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYGSHDIFRADNQ 349
           AP  + L GL A GK+ LAH LA  L   G + +V D    R+   AL       RAD  
Sbjct: 4   APSTLWLTGLSAAGKTTLAHALAEALTAAGAACQVLDGDVVRQ---ALSRDLGFSRADRS 60

Query: 350 QGSAIRRQSAHEAVQDAVIWLKDGNSVAIFDVTNITREQRRE 475
           Q   IRR      V D    L D  S AI  V +  R  R +
Sbjct: 61  QN--IRR------VADRCRQLNDAGSWAIAAVISPYRADREQ 94


>UniRef50_Q15XY1 Cluster: AAA ATPase, central region; n=1;
           Pseudoalteromonas atlantica T6c|Rep: AAA ATPase, central
           region - Pseudoalteromonas atlantica (strain T6c /
           BAA-1087)
          Length = 668

 Score = 35.9 bits (79), Expect = 0.67
 Identities = 23/71 (32%), Positives = 39/71 (54%), Gaps = 2/71 (2%)
 Frame = +2

Query: 158 ISQFAPLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYGSH--DI 331
           ++Q AP+ I L G P  GK+  AH LA+  ++N  S +   CS+   +++    S+  +I
Sbjct: 456 LAQHAPIRILLSGEPGTGKTAFAHHLAKQHDFNLVSVR---CSDVLSKYIGESESNIANI 512

Query: 332 FRADNQQGSAI 364
           F    Q G+A+
Sbjct: 513 FYDAQQHGNAL 523


>UniRef50_Q382A0 Cluster: Putative uncharacterized protein; n=1;
           Trypanosoma brucei|Rep: Putative uncharacterized protein
           - Trypanosoma brucei
          Length = 936

 Score = 35.5 bits (78), Expect = 0.88
 Identities = 18/49 (36%), Positives = 24/49 (48%)
 Frame = +1

Query: 121 ETSSTRNDPLASYQSICAAPHSPGWSASSWQESAGTPTCQTSQLEWRKH 267
           E S   + P+ S  S C   HS G   +S Q S  + T QT+  + RKH
Sbjct: 753 EASEEAHQPITSETSCCTPSHSQGNDQASGQLSGSSSTAQTAASQPRKH 801


>UniRef50_Q12471 Cluster: 6-phosphofructo-2-kinase 2; n=2;
           Saccharomyces cerevisiae|Rep: 6-phosphofructo-2-kinase 2
           - Saccharomyces cerevisiae (Baker's yeast)
          Length = 397

 Score = 35.5 bits (78), Expect = 0.88
 Identities = 41/164 (25%), Positives = 71/164 (43%), Gaps = 19/164 (11%)
 Frame = +2

Query: 131 APATIRSRRISQFAPLLIALVGLPARGKSQLAHRLARHLN----WNGESTKVFDCSEYRR 298
           A  T  + ++++F   +I L+GLPA GKS ++  L + L      N    KVF+  + RR
Sbjct: 85  ADPTYTNGKVNKF---MIVLIGLPATGKSTISSHLIQCLKNNPLTNSLRCKVFNAGKIRR 141

Query: 299 RHMALYGSHDIFRADNQQGSAIRRQSAHEAVQDAVIWLK--------DGNSVAIFDVTNI 454
           +      S  +  ++         ++  +    A I L+        D   V IFD TN 
Sbjct: 142 QISCATISKPLLLSNTSSEDLFNPKNNDKKETYARITLQKLFHEINNDECDVGIFDATNS 201

Query: 455 TREQRREL-SDYC------LSDMGFRILFIECVCEDQELLERNI 565
           T E+RR +  + C      LS      + ++  C ++  ++ NI
Sbjct: 202 TIERRRFIFEEVCSFNTDELSSFNLVPIILQVSCFNRSFIKYNI 245


>UniRef50_A1ZHR3 Cluster: Putative uncharacterized protein; n=1;
           Microscilla marina ATCC 23134|Rep: Putative
           uncharacterized protein - Microscilla marina ATCC 23134
          Length = 529

 Score = 35.1 bits (77), Expect = 1.2
 Identities = 34/131 (25%), Positives = 65/131 (49%), Gaps = 4/131 (3%)
 Frame = +2

Query: 179 LIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYGSHDIFRADNQQG- 355
           L+ + G  A GK+ LA ++A+H+N      + F+ S+  R+ MA   +++  R+++ Q  
Sbjct: 345 LVVVYGGVATGKTTLAQKIAKHMN-----IQHFN-SDLIRKKMAGIPTYERTRSEDLQRV 398

Query: 356 -SAIRRQSAHEAVQDAVIWLKDGNSVAIFDVT--NITREQRRELSDYCLSDMGFRILFIE 526
            S    +  +E + +  I        +I D T  +IT+ +R  L          R++FIE
Sbjct: 399 YSTEMTEKVYETLIEEGINCAFQEGTSILDATFRDITKLER--LLKKVREAQPLRVVFIE 456

Query: 527 CVCEDQELLER 559
            +  D+E+ +R
Sbjct: 457 AIAPDEEIKQR 467


>UniRef50_Q8YNC2 Cluster: All4644 protein; n=6; Cyanobacteria|Rep:
           All4644 protein - Anabaena sp. (strain PCC 7120)
          Length = 190

 Score = 34.7 bits (76), Expect = 1.5
 Identities = 37/111 (33%), Positives = 51/111 (45%), Gaps = 1/111 (0%)
 Frame = +2

Query: 179 LIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYGSHDIFRADNQQGS 358
           LI L+GLP  GKS LA +L           ++      R +   L+GS  I      QGS
Sbjct: 11  LILLIGLPGSGKSTLAKQLVAQC----PQMQLISTDAIRGQ---LFGSEAI------QGS 57

Query: 359 -AIRRQSAHEAVQDAVIWLKDGNSVAIFDVTNITREQRRELSDYCLSDMGF 508
             +  +   + +Q  VI  K    +A+FD TN  R  RREL     S++GF
Sbjct: 58  WLLIWREIEQQLQQTVITGK----IALFDATNAQRRHRRELITLA-SELGF 103


>UniRef50_O46079 Cluster: CG3587-PA; n=3; Diptera|Rep: CG3587-PA -
           Drosophila melanogaster (Fruit fly)
          Length = 299

 Score = 34.7 bits (76), Expect = 1.5
 Identities = 35/123 (28%), Positives = 49/123 (39%)
 Frame = +2

Query: 179 LIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYGSHDIFRADNQQGS 358
           L+ + GLPA GKS  A +L  H    G   KV   SE      A +G +     D+Q+  
Sbjct: 3   LVVITGLPASGKSTRARQLRDHFVERGR--KVHLISENEAVPKAGFGKNS-HTGDSQKEK 59

Query: 359 AIRRQSAHEAVQDAVIWLKDGNSVAIFDVTNITREQRRELSDYCLSDMGFRILFIECVCE 538
            +R     EA +       +   + I D  N  +  R EL  YC+S +          C 
Sbjct: 60  VVRSDLKSEASRHL-----NQEDLVILDAGNYIKGYRYEL--YCMSKVSRTTQCTVFTCI 112

Query: 539 DQE 547
            QE
Sbjct: 113 PQE 115


>UniRef50_A0CEM5 Cluster: Chromosome undetermined scaffold_172,
           whole genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_172,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 150

 Score = 34.7 bits (76), Expect = 1.5
 Identities = 17/52 (32%), Positives = 27/52 (51%)
 Frame = +2

Query: 395 DAVIWLKDGNSVAIFDVTNITREQRRELSDYCLSDMGFRILFIECVCEDQEL 550
           D +I+L + N   I +   I  + +R++  YC S    R  FIEC+ +  EL
Sbjct: 39  DKIIYLMNLNDSQIVEYQQIQNKYQRKVLKYCWSSQSNREQFIECMLKKNEL 90


>UniRef50_UPI0000D9C495 Cluster: PREDICTED: similar to pleckstrin
           and Sec7 domain containing; n=1; Macaca mulatta|Rep:
           PREDICTED: similar to pleckstrin and Sec7 domain
           containing - Macaca mulatta
          Length = 972

 Score = 34.3 bits (75), Expect = 2.0
 Identities = 32/105 (30%), Positives = 43/105 (40%), Gaps = 5/105 (4%)
 Frame = +1

Query: 52  PRTRE**WRPGSSTGHGNDGGQRETSSTRNDPLASYQSICAAPHSPGWSASSWQESAGTP 231
           PR     W P S TG    G Q      R    AS + +   P +PG  + SW     +P
Sbjct: 181 PRVAPSPWAPSSPTGQPPPGAQSSVVIFRFVEKASVRPLNGLP-APGGLSRSWDLGGVSP 239

Query: 232 TCQTSQLEWRKHQSVRLQRVSS---PAYGLVRQP--RHLPRGQPA 351
              T  L    ++ +RL+  +S   PA G    P  R+L  G PA
Sbjct: 240 PRPTPALGPGSNRKLRLEASTSDPLPARGGSALPGSRNLVHGPPA 284


>UniRef50_UPI0000DC2245 Cluster: integrin, alpha D; n=4;
           Eutheria|Rep: integrin, alpha D - Rattus norvegicus
          Length = 1199

 Score = 34.3 bits (75), Expect = 2.0
 Identities = 13/30 (43%), Positives = 19/30 (63%)
 Frame = -2

Query: 158 YDASGSLRVLEVSLCPPSLPWPVLDPGRHY 69
           Y A+G   V++++   P   WP L+PGRHY
Sbjct: 233 YTATGIRTVVDLNTLLPLCVWPALEPGRHY 262


>UniRef50_Q8IVG0 Cluster: Pleckstrin and Sec7 domain-containing
           protein; n=21; Theria|Rep: Pleckstrin and Sec7
           domain-containing protein - Homo sapiens (Human)
          Length = 1091

 Score = 34.3 bits (75), Expect = 2.0
 Identities = 32/105 (30%), Positives = 43/105 (40%), Gaps = 5/105 (4%)
 Frame = +1

Query: 52  PRTRE**WRPGSSTGHGNDGGQRETSSTRNDPLASYQSICAAPHSPGWSASSWQESAGTP 231
           PR     W P S TG    G Q      R    AS + +   P +PG  + SW     +P
Sbjct: 143 PRVAPSPWAPSSPTGQPPPGAQSSVVIFRFVEKASVRPLNGLP-APGGLSRSWDLGGVSP 201

Query: 232 TCQTSQLEWRKHQSVRLQRVSS---PAYGLVRQP--RHLPRGQPA 351
              T  L    ++ +RL+  +S   PA G    P  R+L  G PA
Sbjct: 202 PRPTPALGPGSNRKLRLEASTSDPLPARGGSALPGSRNLVHGPPA 246


>UniRef50_A2QCT7 Cluster: Similarity to hypothetical protein
           EAA59178.1 - Aspergillus nidulans; n=1; Aspergillus
           niger|Rep: Similarity to hypothetical protein EAA59178.1
           - Aspergillus nidulans - Aspergillus niger
          Length = 400

 Score = 34.3 bits (75), Expect = 2.0
 Identities = 38/123 (30%), Positives = 50/123 (40%), Gaps = 15/123 (12%)
 Frame = +2

Query: 95  ATAMMEDKEKLLAPATIRSRRISQFAPLL-----IALVGL-----PARGKSQLAHRLAR- 241
           AT    D E+   P TI + R  + A +      +ALVGL     PAR       RL   
Sbjct: 220 ATPPHLDDEQPTTPITITTARERKDASICHQTYNVALVGLVPQLRPARLLDPTLFRLFHY 279

Query: 242 -HLNWNGESTKVF-DCSEYRRR--HMALYGSHDIFRADNQQGSAIRRQSAHEAVQDAVIW 409
            HL W G +  +  D  E   R   + L G+      D ++    R     EAVQ   +W
Sbjct: 280 THLTWTGSAAAIRQDLIELSDRWAELGLQGTCPYSLTDEERERHAREYEDFEAVQGLKLW 339

Query: 410 LKD 418
           LKD
Sbjct: 340 LKD 342


>UniRef50_Q0SJ89 Cluster: Possible hydrolase; n=3; Bacteria|Rep:
           Possible hydrolase - Rhodococcus sp. (strain RHA1)
          Length = 489

 Score = 33.9 bits (74), Expect = 2.7
 Identities = 24/61 (39%), Positives = 32/61 (52%)
 Frame = +1

Query: 121 ETSSTRNDPLASYQSICAAPHSPGWSASSWQESAGTPTCQTSQLEWRKHQSVRLQRVSSP 300
           ETS  R+ P  +     AAP +P  S SSW +++ T TC TS       +S RL   SSP
Sbjct: 249 ETSPVRSVPTVTASRSTAAP-APRRSNSSWPKASRTTTCTTSPT-----RSGRLSTPSSP 302

Query: 301 A 303
           +
Sbjct: 303 S 303


>UniRef50_Q0M695 Cluster: Protein-tyrosine kinase; n=1; Caulobacter
           sp. K31|Rep: Protein-tyrosine kinase - Caulobacter sp.
           K31
          Length = 750

 Score = 33.5 bits (73), Expect = 3.6
 Identities = 34/117 (29%), Positives = 54/117 (46%), Gaps = 7/117 (5%)
 Frame = +2

Query: 170 APLLIALVG-LPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYGSHDIFRADN 346
           AP +I +   LP  GKS  +  LAR +  +G S  + DC   RR   AL+ +      D 
Sbjct: 552 APQVIVITSALPREGKSMTSVCLARSIAMSGSSVVLVDCDLRRRGSSALFDAAPHGLVDV 611

Query: 347 QQGSA-IRRQSAHEAVQDA-VIWLKDG-NSVA-IFDVTNITR--EQRRELSDYCLSD 499
            +G   +R     +   DA ++ ++ G NS+  +F   N+ +  +  R   DY L D
Sbjct: 612 LEGKVPLRDALVKDDRTDAWILPVRSGPNSIRDLFATPNMDQVLQSLRASFDYVLLD 668


>UniRef50_Q4PD00 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 173

 Score = 33.5 bits (73), Expect = 3.6
 Identities = 25/86 (29%), Positives = 43/86 (50%)
 Frame = +2

Query: 23  ETRSGFSEKTLVQENSNGARDLARATAMMEDKEKLLAPATIRSRRISQFAPLLIALVGLP 202
           + R+G S+++    + +  R+ AR +A  +  ++L     + SRR      LL+ + G+P
Sbjct: 5   DNRTGESDRSDAGPSRSAGRESARKSARAQCHDRL-----VPSRR------LLVGVSGIP 53

Query: 203 ARGKSQLAHRLARHLNWNGESTKVFD 280
             GKS LA +L   LN     T+  D
Sbjct: 54  GSGKSSLAVKLVASLNARSRCTQSTD 79


>UniRef50_A5DQ35 Cluster: Putative uncharacterized protein; n=1;
           Pichia guilliermondii|Rep: Putative uncharacterized
           protein - Pichia guilliermondii (Yeast) (Candida
           guilliermondii)
          Length = 218

 Score = 33.5 bits (73), Expect = 3.6
 Identities = 13/27 (48%), Positives = 21/27 (77%)
 Frame = +2

Query: 176 LLIALVGLPARGKSQLAHRLARHLNWN 256
           +LIAL G+P  GKS +A+R++ ++N N
Sbjct: 21  VLIALAGVPGSGKSTIANRISNYMNTN 47


>UniRef50_Q6ZSZ6 Cluster: Teashirt homolog 1; n=27; Tetrapoda|Rep:
           Teashirt homolog 1 - Homo sapiens (Human)
          Length = 1077

 Score = 33.5 bits (73), Expect = 3.6
 Identities = 26/86 (30%), Positives = 41/86 (47%), Gaps = 3/86 (3%)
 Frame = +1

Query: 76  RPGSSTGHGNDGGQRETSS-TRNDPLASYQSICAAPHSPGWS-ASSWQESAGTPTCQTSQ 249
           +   ST   ND  Q+E+S+ T   P     +      +P  S +SS   S+ T T  +S 
Sbjct: 137 KKSGSTTSTNDASQKESSAPTPTPPTCPVSTTGPTTSTPSTSCSSSTSHSSTTSTSSSSG 196

Query: 250 LEWRKHQSVR-LQRVSSPAYGLVRQP 324
            +W +    + LQ+ SS  YGL+ +P
Sbjct: 197 YDWHQAALAKTLQQTSS--YGLLPEP 220


>UniRef50_Q4SUU0 Cluster: Chromosome undetermined SCAF13842, whole
           genome shotgun sequence; n=2; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF13842,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 783

 Score = 33.1 bits (72), Expect = 4.7
 Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 4/78 (5%)
 Frame = +1

Query: 82  GSSTGHGNDGGQRETSSTRNDPLASYQSICAAPHSPGWSASSWQESAGT----PTCQTSQ 249
           G   G G  GGQ   SS  N+  +S  S+ AAP  P  +AS   E   +      C +SQ
Sbjct: 583 GGGGGGGGGGGQDSPSSCCNNSSSSRPSLSAAPR-PSRAASRSSELVESLKLMSLCLSSQ 641

Query: 250 LEWRKHQSVRLQRVSSPA 303
           L+ ++ Q  + Q++   A
Sbjct: 642 LQLQQQQQQQQQQLQQRA 659


>UniRef50_A4ZPY4 Cluster: DepD; n=3; Chromobacterium violaceum|Rep:
           DepD - Chromobacterium violaceum
          Length = 3057

 Score = 33.1 bits (72), Expect = 4.7
 Identities = 32/126 (25%), Positives = 44/126 (34%), Gaps = 9/126 (7%)
 Frame = +2

Query: 74  GARDLARATAMMEDKEKLLAPATIRSRRISQFAPLLIALVG-----LPARGKSQLAHRLA 238
           GA D A    + E KE+LL        R +  AP      G      P + +   A RL 
Sbjct: 31  GALDAALVARLREAKEELLRVLDDEGARAAPLAPAQPGEAGDAAALSPGQARLVAATRLG 90

Query: 239 RHLNWNGEST----KVFDCSEYRRRHMALYGSHDIFRADNQQGSAIRRQSAHEAVQDAVI 406
               +N ++        D     R   AL   HDI R     G  +R+    E +     
Sbjct: 91  DPAMYNEQAAIELADAVDAEAVARAFAALARRHDILRTVFSDGEPVRQTVLPEPIVTLQA 150

Query: 407 WLKDGN 424
           W  DG+
Sbjct: 151 WTVDGD 156


>UniRef50_Q7QBY9 Cluster: ENSANGP00000014942; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000014942 - Anopheles gambiae
           str. PEST
          Length = 409

 Score = 33.1 bits (72), Expect = 4.7
 Identities = 22/59 (37%), Positives = 31/59 (52%), Gaps = 2/59 (3%)
 Frame = +1

Query: 76  RPGSSTGHGNDGGQRETSSTRNDPLASYQSICAAPHSPG--WSASSWQESAGTPTCQTS 246
           RP   +G+GN GG  + SST N    S  S  A+  SP    S S+   S+G P+ Q++
Sbjct: 345 RPSQHSGNGNVGGSYQVSSTGNG--FSQASFSASSFSPNGRTSLSAGGFSSGAPSAQSA 401


>UniRef50_Q6CP70 Cluster: Kluyveromyces lactis strain NRRL Y-1140
           chromosome E of strain NRRL Y- 1140 of Kluyveromyces
           lactis; n=1; Kluyveromyces lactis|Rep: Kluyveromyces
           lactis strain NRRL Y-1140 chromosome E of strain NRRL Y-
           1140 of Kluyveromyces lactis - Kluyveromyces lactis
           (Yeast) (Candida sphaerica)
          Length = 455

 Score = 33.1 bits (72), Expect = 4.7
 Identities = 31/111 (27%), Positives = 55/111 (49%), Gaps = 15/111 (13%)
 Frame = +2

Query: 182 IALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYR----------RRHMALYGSHDI 331
           + L+GLPA GKS ++  L   L+ +  ST    CS +           RR ++ + + ++
Sbjct: 109 VILIGLPATGKSTISRHLINFLH-SSRSTAHLRCSIFNAGNVRRKLSTRRQVSPFMAPEL 167

Query: 332 FRAD----NQQGSAIRRQSAHEAVQDAVIWLK-DGNSVAIFDVTNITREQR 469
            +++    N + S  + + A  A+   +  LK D   +AIFD TN T ++R
Sbjct: 168 NKSEEDVFNPKNSHKKEEYARIALSKLLNDLKQDRCDLAIFDATNSTLQRR 218


>UniRef50_Q99456 Cluster: Keratin, type I cytoskeletal 12; n=251;
           Euteleostomi|Rep: Keratin, type I cytoskeletal 12 - Homo
           sapiens (Human)
          Length = 494

 Score = 33.1 bits (72), Expect = 4.7
 Identities = 25/73 (34%), Positives = 32/73 (43%), Gaps = 11/73 (15%)
 Frame = +1

Query: 82  GSSTG--HGNDGG-----QRETSSTRNDPLASYQSICAAPHSPGWSASS----WQESAGT 228
           G S G   GNDGG     ++ET    ND LASY     A         +    W E+ GT
Sbjct: 107 GGSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGT 166

Query: 229 PTCQTSQLEWRKH 267
            T   SQ ++ K+
Sbjct: 167 GTADASQSDYSKY 179


>UniRef50_UPI00015B551A Cluster: PREDICTED: hypothetical protein;
           n=1; Nasonia vitripennis|Rep: PREDICTED: hypothetical
           protein - Nasonia vitripennis
          Length = 641

 Score = 32.7 bits (71), Expect = 6.2
 Identities = 19/63 (30%), Positives = 35/63 (55%), Gaps = 4/63 (6%)
 Frame = +2

Query: 128 LAPATIRSRR---ISQFAPLLIALVGLPARGKSQLAHRLARHLNWNGESTKV-FDCSEYR 295
           +  +TIR +    I +  PL+   +G    GK++LA +LA +++ N   + +  D SEY+
Sbjct: 296 IVASTIRRKENGWIDEEHPLVFLFLGSSGIGKTELAKQLAAYIHRNKPDSFIRLDMSEYQ 355

Query: 296 RRH 304
            +H
Sbjct: 356 EKH 358


>UniRef50_Q98P10 Cluster: Sensor histidine kinase of two-component;
           n=1; Mesorhizobium loti|Rep: Sensor histidine kinase of
           two-component - Rhizobium loti (Mesorhizobium loti)
          Length = 604

 Score = 32.7 bits (71), Expect = 6.2
 Identities = 26/98 (26%), Positives = 46/98 (46%)
 Frame = +2

Query: 95  ATAMMEDKEKLLAPATIRSRRISQFAPLLIALVGLPARGKSQLAHRLARHLNWNGESTKV 274
           AT  +    K+    T  +R   Q   +L+  V    + +  +   + R  N   E+ K 
Sbjct: 379 ATGQIVGASKIARDIT-SARENEQRIRMLMREVNHRVKNQYSVILSMIRETNKRSETPKQ 437

Query: 275 FDCSEYRRRHMALYGSHDIFRADNQQGSAIRRQSAHEA 388
           F+ ++ R+R MAL  SHD+  + + +G+ IR   A +A
Sbjct: 438 FE-AQVRQRIMALSRSHDLLVSADWKGATIRELLAAQA 474


>UniRef50_A4E6S7 Cluster: Putative uncharacterized protein; n=1;
           Collinsella aerofaciens ATCC 25986|Rep: Putative
           uncharacterized protein - Collinsella aerofaciens ATCC
           25986
          Length = 461

 Score = 32.7 bits (71), Expect = 6.2
 Identities = 30/88 (34%), Positives = 39/88 (44%), Gaps = 6/88 (6%)
 Frame = +2

Query: 173 PLLIALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYR---RRHMALYGSH---DIF 334
           P +I LVGL   GK+  A +LA  L   G S  +  C  YR      +A  G      +F
Sbjct: 70  PNVIMLVGLQGSGKTTAAVKLAYLLKKQGRSPLLVACDVYRPAAADQLATLGGEIGVPVF 129

Query: 335 RADNQQGSAIRRQSAHEAVQDAVIWLKD 418
           R D      I    A  A+Q+AV  L+D
Sbjct: 130 RGDGAHPVDI----AKGAIQEAVDHLRD 153


>UniRef50_A0VJZ9 Cluster: Adenylyl-sulfate kinase; n=7;
           Proteobacteria|Rep: Adenylyl-sulfate kinase - Delftia
           acidovorans SPH-1
          Length = 228

 Score = 32.7 bits (71), Expect = 6.2
 Identities = 21/55 (38%), Positives = 26/55 (47%)
 Frame = +2

Query: 182 IALVGLPARGKSQLAHRLARHLNWNGESTKVFDCSEYRRRHMALYGSHDIFRADN 346
           I L GL   GKS +A+ L  HL+  G  T V D    R R     G  +  RA+N
Sbjct: 35  IWLTGLSGSGKSTIANALQAHLHAAGRRTYVLDGDNIRSRLNRDLGFSEEDRAEN 89


>UniRef50_Q4DTE1 Cluster: Putative uncharacterized protein; n=2;
           Trypanosoma cruzi|Rep: Putative uncharacterized protein
           - Trypanosoma cruzi
          Length = 994

 Score = 32.7 bits (71), Expect = 6.2
 Identities = 20/64 (31%), Positives = 31/64 (48%)
 Frame = -3

Query: 502 HIREAVVAQLTALLPSYIGNVKYSNTVPILEPDDGVLYGLVCALTTNCGPLLVVRAEDVV 323
           H+    V     L+   IG+VK       LE     L+G++ AL +   PLL++ +E VV
Sbjct: 542 HVGFKQVNVFLGLVRDIIGDVKMLENEKSLEAIKASLFGMLSALFSVVNPLLLLESEHVV 601

Query: 322 AAVQ 311
             +Q
Sbjct: 602 TLLQ 605


>UniRef50_P19532 Cluster: Transcription factor E3; n=32;
           Euteleostomi|Rep: Transcription factor E3 - Homo sapiens
           (Human)
          Length = 743

 Score = 32.7 bits (71), Expect = 6.2
 Identities = 33/119 (27%), Positives = 46/119 (38%), Gaps = 4/119 (3%)
 Frame = +1

Query: 100 GNDGGQRETSSTRNDPLASYQSICAAPHSPGWSASSWQESAGTPTCQTSQLEW----RKH 267
           G  GG        +DPL S  S+ +   +   +AS+W+ S      Q S L W    RK 
Sbjct: 535 GLSGGALSPLRAASDPLLSSVSLLSPRPAAAAAASAWKRSPD----QASPLPWTFPPRKG 590

Query: 268 QSVRLQRVSSPAYGLVRQPRHLPRGQPARVXXXXXXXXXXXXXXXHLAQGWEQCCYI*R 444
             VR++    P +  +R PR+L RG   R                   +G  QC Y  R
Sbjct: 591 GPVRMRPRLFP-HPPMRLPRYLGRGDVIRPHPCNQARRRSQMRPCTFPKGTAQCRYFRR 648


>UniRef50_UPI0000EBEE4D Cluster: PREDICTED: hypothetical protein;
           n=1; Bos taurus|Rep: PREDICTED: hypothetical protein -
           Bos taurus
          Length = 110

 Score = 32.3 bits (70), Expect = 8.2
 Identities = 18/56 (32%), Positives = 25/56 (44%)
 Frame = +1

Query: 121 ETSSTRNDPLASYQSICAAPHSPGWSASSWQESAGTPTCQTSQLEWRKHQSVRLQR 288
           ET     DP    +++ A   S   S +  QE    P C T+Q  W++    RLQR
Sbjct: 47  ETCGLERDPREDQEAVAAGHESGPLSVAKSQEGWPKPKCWTAQ-HWKRLPDSRLQR 101


>UniRef50_Q72F24 Cluster: Putative uncharacterized protein; n=2;
           Desulfovibrio vulgaris subsp. vulgaris|Rep: Putative
           uncharacterized protein - Desulfovibrio vulgaris (strain
           Hildenborough / ATCC 29579 / NCIMB8303)
          Length = 313

 Score = 32.3 bits (70), Expect = 8.2
 Identities = 16/43 (37%), Positives = 20/43 (46%)
 Frame = +1

Query: 76  RPGSSTGHGNDGGQRETSSTRNDPLASYQSICAAPHSPGWSAS 204
           R   S  HG  G  R T   +NDP    +S  A P SP  +A+
Sbjct: 89  RAAGSITHGESGVSRRTGPPKNDPFRHGRSANATPQSPFGTAT 131


>UniRef50_A6LX20 Cluster: Conserved hypothetical membrane spanning
           protein; n=2; Firmicutes|Rep: Conserved hypothetical
           membrane spanning protein - Clostridium beijerinckii
           NCIMB 8052
          Length = 279

 Score = 32.3 bits (70), Expect = 8.2
 Identities = 21/78 (26%), Positives = 36/78 (46%), Gaps = 4/78 (5%)
 Frame = +2

Query: 209 GKSQLAHRLARHLN---WNGESTKV-FDCSEYRRRHMALYGSHDIFRADNQQGSAIRRQS 376
           GK QL   +    N   W GE  ++ FD  E  R   +L  +H++F+        IR  +
Sbjct: 145 GKFQLDKGIKTFQNDIIWAGEEGRLYFDLDEEERMKDSLKTAHELFKNQKDWSDRIRAYA 204

Query: 377 AHEAVQDAVIWLKDGNSV 430
           A E ++ A  W+ + + +
Sbjct: 205 ASELLELANDWIDEEDEI 222


>UniRef50_A3A1N0 Cluster: Putative uncharacterized protein; n=1;
           Oryza sativa (japonica cultivar-group)|Rep: Putative
           uncharacterized protein - Oryza sativa subsp. japonica
           (Rice)
          Length = 481

 Score = 32.3 bits (70), Expect = 8.2
 Identities = 17/58 (29%), Positives = 31/58 (53%)
 Frame = +1

Query: 82  GSSTGHGNDGGQRETSSTRNDPLASYQSICAAPHSPGWSASSWQESAGTPTCQTSQLE 255
           G S G+ N   +R T++   + + +  SI A+P +  W+ASS +   G  T + S ++
Sbjct: 392 GGSGGNTNGSHRRITAAAAINIIRTLLSILASPAAVDWTASSGRRLTGCSTLRCSSVD 449


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 577,039,844
Number of Sequences: 1657284
Number of extensions: 11600851
Number of successful extensions: 42786
Number of sequences better than 10.0: 102
Number of HSP's better than 10.0 without gapping: 40929
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 42709
length of database: 575,637,011
effective HSP length: 96
effective length of database: 416,537,747
effective search space used: 38738010471
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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