BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= P5PG0587 (584 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q16JY0 Cluster: Inositol triphosphate 3-kinase c; n=1; ... 198 8e-50 UniRef50_Q8SXS8 Cluster: RE35745p; n=5; Endopterygota|Rep: RE357... 192 4e-48 UniRef50_Q963D5 Cluster: 1D-myo-inositol-trisphosphate 3-kinase ... 179 5e-44 UniRef50_Q5RGF8 Cluster: Novel protein similar to vertebrate ino... 175 8e-43 UniRef50_UPI0000EB3685 Cluster: UPI0000EB3685 related cluster; n... 170 2e-41 UniRef50_P27987 Cluster: Inositol-trisphosphate 3-kinase B; n=19... 169 3e-41 UniRef50_P42335 Cluster: Inositol-trisphosphate 3-kinase B; n=28... 168 1e-40 UniRef50_P23677 Cluster: Inositol-trisphosphate 3-kinase A; n=12... 155 7e-37 UniRef50_UPI0000F2D259 Cluster: PREDICTED: similar to inositol 1... 151 1e-35 UniRef50_Q2TAE4 Cluster: LOC494865 protein; n=6; Euteleostomi|Re... 142 5e-33 UniRef50_Q96DU7 Cluster: Inositol-trisphosphate 3-kinase C; n=7;... 137 2e-31 UniRef50_Q8JFU9 Cluster: Novel protein similar to vertebrate ino... 134 2e-30 UniRef50_UPI0000F21BCC Cluster: PREDICTED: similar to inositol 1... 132 8e-30 UniRef50_Q95Q62 Cluster: Let-23 fertility effector/regulator pro... 118 8e-26 UniRef50_Q9VL83 Cluster: CG4026-PA; n=5; Diptera|Rep: CG4026-PA ... 108 8e-23 UniRef50_A3EXV5 Cluster: Inositol 1,4,5-triphosphate kinase 1-li... 108 1e-22 UniRef50_Q5DHU6 Cluster: SJCHGC06700 protein; n=1; Schistosoma j... 107 1e-22 UniRef50_UPI0001556459 Cluster: PREDICTED: similar to Inositol 1... 67 2e-10 UniRef50_UPI00015B4C69 Cluster: PREDICTED: similar to inositol t... 61 2e-08 UniRef50_A2ELN6 Cluster: Putative uncharacterized protein; n=1; ... 34 2.8 UniRef50_A6CXX6 Cluster: YkgB; n=1; Vibrio shilonii AK1|Rep: Ykg... 33 3.8 UniRef50_Q4N2C0 Cluster: Putative uncharacterized protein; n=2; ... 33 5.0 UniRef50_Q39VQ4 Cluster: Putative uncharacterized protein; n=3; ... 33 6.6 UniRef50_A6C743 Cluster: Putative uncharacterized protein; n=1; ... 33 6.6 UniRef50_UPI00006CE914 Cluster: hypothetical protein TTHERM_0055... 32 8.7 UniRef50_Q82Z99 Cluster: HD/KH domain protein; n=11; Bacilli|Rep... 32 8.7 UniRef50_A6RXF1 Cluster: Putative uncharacterized protein; n=3; ... 32 8.7 >UniRef50_Q16JY0 Cluster: Inositol triphosphate 3-kinase c; n=1; Aedes aegypti|Rep: Inositol triphosphate 3-kinase c - Aedes aegypti (Yellowfever mosquito) Length = 387 Score = 198 bits (483), Expect = 8e-50 Identities = 86/126 (68%), Positives = 108/126 (85%) Frame = +2 Query: 206 YMIWRETISSTSTLGFRIDGVKKADGTSSKDFKTTKTRQQIAEAFKDFTSSCPNAAVRYL 385 YM+WRETISSTSTLGFRI+G+KK+DGTSSKDFKTTK+R+QI EAF++FT P+A +Y+ Sbjct: 126 YMVWRETISSTSTLGFRIEGIKKSDGTSSKDFKTTKSREQIIEAFREFTEGFPHALPKYI 185 Query: 386 ERLRSIRATLTESHFFRTHELIGSSLLFVHDKRKASIWMIDFAKTVPVPENVSIDHNTTW 565 +RL++IRATL+ S FF+ HE+IGSSLLFVHD+ AS+W+IDFAKTV +P+ V I H W Sbjct: 186 QRLKAIRATLSYSDFFKRHEVIGSSLLFVHDRHNASVWLIDFAKTVTLPDKVDITHENKW 245 Query: 566 KVGNHE 583 KVGNHE Sbjct: 246 KVGNHE 251 Score = 83.4 bits (197), Expect = 4e-15 Identities = 39/57 (68%), Positives = 41/57 (71%) Frame = +1 Query: 34 PGVMDCKIGVRTYXXXXXXXXXXXXXXRKDMYEKMIQIDPKAPSEEEHRSKGVTKPR 204 P VMDCKIGVRTY RKDMYEKMIQIDP AP+EEEHR+KGVTKPR Sbjct: 69 PCVMDCKIGVRTYLEEELSKAKEKPKLRKDMYEKMIQIDPNAPTEEEHRAKGVTKPR 125 >UniRef50_Q8SXS8 Cluster: RE35745p; n=5; Endopterygota|Rep: RE35745p - Drosophila melanogaster (Fruit fly) Length = 669 Score = 192 bits (469), Expect = 4e-48 Identities = 87/126 (69%), Positives = 106/126 (84%) Frame = +2 Query: 206 YMIWRETISSTSTLGFRIDGVKKADGTSSKDFKTTKTRQQIAEAFKDFTSSCPNAAVRYL 385 YM+WRETISST+TLGFRI+G+KK+DGTSSKDFKTTK+R+QI AF +F S P+ RY+ Sbjct: 489 YMVWRETISSTATLGFRIEGIKKSDGTSSKDFKTTKSREQIKLAFLEFLSGHPHILPRYI 548 Query: 386 ERLRSIRATLTESHFFRTHELIGSSLLFVHDKRKASIWMIDFAKTVPVPENVSIDHNTTW 565 +RLR+IRATL S FF+THE+IGSSLLFVHD+ ASIW+IDFAKTV +P + IDH + W Sbjct: 549 QRLRAIRATLAVSEFFQTHEVIGSSLLFVHDQTHASIWLIDFAKTVELPPQLRIDHYSAW 608 Query: 566 KVGNHE 583 KVGNHE Sbjct: 609 KVGNHE 614 Score = 71.3 bits (167), Expect = 2e-11 Identities = 33/59 (55%), Positives = 38/59 (64%) Frame = +1 Query: 28 IVPGVMDCKIGVRTYXXXXXXXXXXXXXXRKDMYEKMIQIDPKAPSEEEHRSKGVTKPR 204 + P VMDCK+GVRTY RKDMY+KMIQID AP+ EEH +K VTKPR Sbjct: 430 VQPCVMDCKVGVRTYLEEELSKAKEKPKLRKDMYDKMIQIDSHAPTAEEHAAKAVTKPR 488 >UniRef50_Q963D5 Cluster: 1D-myo-inositol-trisphosphate 3-kinase isoform A; n=4; Apocrita|Rep: 1D-myo-inositol-trisphosphate 3-kinase isoform A - Apis mellifera (Honeybee) Length = 782 Score = 179 bits (435), Expect = 5e-44 Identities = 78/127 (61%), Positives = 103/127 (81%), Gaps = 1/127 (0%) Frame = +2 Query: 206 YMIWRETISSTSTLGFRIDGVKKADGTSSKDFKTTKTRQQIAEAFKDFTSSCPNAAVRYL 385 YM+WRETISST+TLGFR++G+K A G SSKDFKTT+TR+Q+ EA + F P+A +Y+ Sbjct: 633 YMVWRETISSTATLGFRVEGIKLAHGGSSKDFKTTRTREQVTEALRRFVEGYPHAVPKYI 692 Query: 386 ERLRSIRATLTESHFFRTHELIGSSLLFVHDKRKASIWMIDFAKTVPVPENV-SIDHNTT 562 +RL++IRATL S FF +HE++GSSLLFVHD + A IWMIDFAKT+P+P+++ I H+ Sbjct: 693 QRLKAIRATLKASPFFASHEVVGSSLLFVHDTKNAGIWMIDFAKTLPLPQHLPRIHHDAE 752 Query: 563 WKVGNHE 583 WKVGNHE Sbjct: 753 WKVGNHE 759 Score = 73.3 bits (172), Expect = 4e-12 Identities = 33/57 (57%), Positives = 38/57 (66%) Frame = +1 Query: 34 PGVMDCKIGVRTYXXXXXXXXXXXXXXRKDMYEKMIQIDPKAPSEEEHRSKGVTKPR 204 P VMDCK+GVRTY RKDMYEKM+Q+DP AP+ EE R +GVTKPR Sbjct: 576 PCVMDCKVGVRTYLESELAKAKERPKLRKDMYEKMVQVDPTAPNAEERRVQGVTKPR 632 >UniRef50_Q5RGF8 Cluster: Novel protein similar to vertebrate inositol 1,4,5-trisphosphate 3- kinase B; n=2; Danio rerio|Rep: Novel protein similar to vertebrate inositol 1,4,5-trisphosphate 3- kinase B - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 395 Score = 175 bits (425), Expect = 8e-43 Identities = 82/140 (58%), Positives = 98/140 (70%), Gaps = 1/140 (0%) Frame = +2 Query: 167 KKSTEVKESRSQGYMIWRETISSTSTLGFRIDGVKKADGTSSKDFKTTKTRQQIAEAFKD 346 +K E K YM WRETISST+TLGFRI+G+KK DGT ++DFK TKTR+Q+ EAF+D Sbjct: 233 EKENEQKAVTKPRYMQWRETISSTATLGFRIEGIKKEDGTVNRDFKKTKTREQVTEAFQD 292 Query: 347 FTSSCPNAAVRYLERLRSIRATLTESHFFRTHELIGSSLLFVHDKRK-ASIWMIDFAKTV 523 F N YL RL+ IR TL S FF+THE+IGSSLLFVHDKR+ A +WMIDF KT Sbjct: 293 FVKGNKNILHSYLNRLKEIRDTLEMSPFFKTHEVIGSSLLFVHDKRELAKVWMIDFGKTT 352 Query: 524 PVPENVSIDHNTTWKVGNHE 583 P+PE + H TW GN E Sbjct: 353 PLPEGQELSHRATWMEGNRE 372 Score = 67.3 bits (157), Expect = 2e-10 Identities = 29/58 (50%), Positives = 38/58 (65%) Frame = +1 Query: 31 VPGVMDCKIGVRTYXXXXXXXXXXXXXXRKDMYEKMIQIDPKAPSEEEHRSKGVTKPR 204 +P VMDCK+G+RTY R DMY+KMI++DP AP+E+E+ K VTKPR Sbjct: 188 LPCVMDCKMGIRTYLEEELTKARKKPSLRADMYQKMIEVDPDAPTEKENEQKAVTKPR 245 >UniRef50_UPI0000EB3685 Cluster: UPI0000EB3685 related cluster; n=1; Canis lupus familiaris|Rep: UPI0000EB3685 UniRef100 entry - Canis familiaris Length = 887 Score = 170 bits (414), Expect = 2e-41 Identities = 75/127 (59%), Positives = 97/127 (76%), Gaps = 1/127 (0%) Frame = +2 Query: 206 YMIWRETISSTSTLGFRIDGVKKADGTSSKDFKTTKTRQQIAEAFKDFTSSCPNAAVRYL 385 YM WRETISST+TLGFRI+G+KK DG+ ++DFK TKTR+Q+ +AFK+FT N + Y Sbjct: 737 YMQWRETISSTATLGFRIEGIKKEDGSVNRDFKKTKTREQVTQAFKEFTKGNRNILIAYR 796 Query: 386 ERLRSIRATLTESHFFRTHELIGSSLLFVHD-KRKASIWMIDFAKTVPVPENVSIDHNTT 562 +RL+ IRATL S FF+ HE+IGSSLLF+HD K +A +WMIDF KT P+PE ++ HN Sbjct: 797 DRLKDIRATLEVSPFFKCHEVIGSSLLFIHDQKEQAKVWMIDFGKTTPLPEGQTLQHNVP 856 Query: 563 WKVGNHE 583 W+ GN E Sbjct: 857 WQEGNRE 863 Score = 68.5 bits (160), Expect = 1e-10 Identities = 30/57 (52%), Positives = 37/57 (64%) Frame = +1 Query: 34 PGVMDCKIGVRTYXXXXXXXXXXXXXXRKDMYEKMIQIDPKAPSEEEHRSKGVTKPR 204 P VMDCK+G+RTY RKDMY+KMI++DP AP+EEE + VTKPR Sbjct: 680 PCVMDCKMGIRTYLEEELTKARKKPSLRKDMYQKMIEVDPDAPTEEEKAQRAVTKPR 736 >UniRef50_P27987 Cluster: Inositol-trisphosphate 3-kinase B; n=19; Euteleostomi|Rep: Inositol-trisphosphate 3-kinase B - Homo sapiens (Human) Length = 946 Score = 169 bits (412), Expect = 3e-41 Identities = 74/127 (58%), Positives = 98/127 (77%), Gaps = 1/127 (0%) Frame = +2 Query: 206 YMIWRETISSTSTLGFRIDGVKKADGTSSKDFKTTKTRQQIAEAFKDFTSSCPNAAVRYL 385 YM WRETISST+TLGFRI+G+KK DGT ++DFK TKTR+Q+ EAF++FT N + Y Sbjct: 796 YMQWRETISSTATLGFRIEGIKKEDGTVNRDFKKTKTREQVTEAFREFTKGNHNILIAYR 855 Query: 386 ERLRSIRATLTESHFFRTHELIGSSLLFVHDKR-KASIWMIDFAKTVPVPENVSIDHNTT 562 +RL++IR TL S FF+ HE+IGSSLLF+HDK+ +A +WMIDF KT P+PE ++ H+ Sbjct: 856 DRLKAIRTTLEVSPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGKTTPLPEGQTLQHDVP 915 Query: 563 WKVGNHE 583 W+ GN E Sbjct: 916 WQEGNRE 922 Score = 69.3 bits (162), Expect = 6e-11 Identities = 30/57 (52%), Positives = 38/57 (66%) Frame = +1 Query: 34 PGVMDCKIGVRTYXXXXXXXXXXXXXXRKDMYEKMIQIDPKAPSEEEHRSKGVTKPR 204 P VMDCK+G+RTY RKDMY+KMI++DP+AP+EEE + VTKPR Sbjct: 739 PCVMDCKMGIRTYLEEELTKARKKPSLRKDMYQKMIEVDPEAPTEEEKAQRAVTKPR 795 >UniRef50_P42335 Cluster: Inositol-trisphosphate 3-kinase B; n=28; Eumetazoa|Rep: Inositol-trisphosphate 3-kinase B - Rattus norvegicus (Rat) Length = 934 Score = 168 bits (408), Expect = 1e-40 Identities = 73/127 (57%), Positives = 98/127 (77%), Gaps = 1/127 (0%) Frame = +2 Query: 206 YMIWRETISSTSTLGFRIDGVKKADGTSSKDFKTTKTRQQIAEAFKDFTSSCPNAAVRYL 385 YM WRETISST+TLGFRI+G+KK DG+ ++DFK TKTR+Q+ EAF++FT N + Y Sbjct: 784 YMQWRETISSTATLGFRIEGIKKEDGSVNRDFKKTKTREQVTEAFREFTKGNQNILIAYR 843 Query: 386 ERLRSIRATLTESHFFRTHELIGSSLLFVHDKR-KASIWMIDFAKTVPVPENVSIDHNTT 562 +RL++IR TL S FF+ HE+IGSSLLF+HDK+ +A +WMIDF KT P+PE ++ H+ Sbjct: 844 DRLKAIRETLEVSPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGKTTPLPEGQTLQHDVP 903 Query: 563 WKVGNHE 583 W+ GN E Sbjct: 904 WQEGNRE 910 Score = 68.9 bits (161), Expect = 8e-11 Identities = 29/57 (50%), Positives = 38/57 (66%) Frame = +1 Query: 34 PGVMDCKIGVRTYXXXXXXXXXXXXXXRKDMYEKMIQIDPKAPSEEEHRSKGVTKPR 204 P VMDCK+G+RTY RKDMY+KM+++DP+AP+EEE + VTKPR Sbjct: 727 PCVMDCKMGIRTYLEEELTKARKKPSLRKDMYQKMVEVDPEAPTEEEKAQRAVTKPR 783 >UniRef50_P23677 Cluster: Inositol-trisphosphate 3-kinase A; n=12; Amniota|Rep: Inositol-trisphosphate 3-kinase A - Homo sapiens (Human) Length = 461 Score = 155 bits (376), Expect = 7e-37 Identities = 70/127 (55%), Positives = 90/127 (70%), Gaps = 1/127 (0%) Frame = +2 Query: 206 YMIWRETISSTSTLGFRIDGVKKADGTSSKDFKTTKTRQQIAEAFKDFTSSCPNAAVRYL 385 YM WRE ISS++TLGFRI+G+KKADG+ S DFKTT++R+Q+ F++F RYL Sbjct: 315 YMQWREGISSSTTLGFRIEGIKKADGSCSTDFKTTRSREQVLRVFEEFVQGDEEVLRRYL 374 Query: 386 ERLRSIRATLTESHFFRTHELIGSSLLFVHDK-RKASIWMIDFAKTVPVPENVSIDHNTT 562 RL+ IR TL S FFR HE+IGSSLLFVHD +A +W+IDF KT P+P+ +DH Sbjct: 375 NRLQQIRDTLEVSEFFRRHEVIGSSLLFVHDHCHRAGVWLIDFGKTTPLPDGQILDHRRP 434 Query: 563 WKVGNHE 583 W+ GN E Sbjct: 435 WEEGNRE 441 Score = 69.7 bits (163), Expect = 5e-11 Identities = 30/57 (52%), Positives = 38/57 (66%) Frame = +1 Query: 34 PGVMDCKIGVRTYXXXXXXXXXXXXXXRKDMYEKMIQIDPKAPSEEEHRSKGVTKPR 204 P V+DCK+GVRTY RKDMY+KM+ +DP+AP+EEEH + VTKPR Sbjct: 258 PCVLDCKMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAPTEEEHAQRAVTKPR 314 >UniRef50_UPI0000F2D259 Cluster: PREDICTED: similar to inositol 1,4,5-trisphosphate 3-kinase C; n=6; Mammalia|Rep: PREDICTED: similar to inositol 1,4,5-trisphosphate 3-kinase C - Monodelphis domestica Length = 719 Score = 151 bits (366), Expect = 1e-35 Identities = 68/127 (53%), Positives = 90/127 (70%), Gaps = 1/127 (0%) Frame = +2 Query: 206 YMIWRETISSTSTLGFRIDGVKKADGTSSKDFKTTKTRQQIAEAFKDFTSSCPNAAVRYL 385 YM WRET+SST+TLGFRI+G+KKADGT + +FK T+ +Q+ A +DF + +Y+ Sbjct: 573 YMQWRETVSSTATLGFRIEGIKKADGTCNTNFKKTQGTEQVTRALEDFVDGDRSLLRKYV 632 Query: 386 ERLRSIRATLTESHFFRTHELIGSSLLFVHDKR-KASIWMIDFAKTVPVPENVSIDHNTT 562 ERL +R TL S FFRTHE++GSSLLFVHD+ A +WMIDF KTVP+P ++ H Sbjct: 633 ERLEELRGTLETSPFFRTHEVVGSSLLFVHDQTGLAKVWMIDFGKTVPLPAPQTLSHRLP 692 Query: 563 WKVGNHE 583 W+ GN E Sbjct: 693 WEEGNRE 699 Score = 65.7 bits (153), Expect = 8e-10 Identities = 28/57 (49%), Positives = 34/57 (59%) Frame = +1 Query: 34 PGVMDCKIGVRTYXXXXXXXXXXXXXXRKDMYEKMIQIDPKAPSEEEHRSKGVTKPR 204 P +MDCK+G RTY R+DMYEKM+ +DP AP+ EEH VTKPR Sbjct: 516 PSIMDCKMGSRTYLEEELAKARERPRPRRDMYEKMVAVDPSAPTPEEHAQGAVTKPR 572 >UniRef50_Q2TAE4 Cluster: LOC494865 protein; n=6; Euteleostomi|Rep: LOC494865 protein - Xenopus laevis (African clawed frog) Length = 516 Score = 142 bits (344), Expect = 5e-33 Identities = 62/127 (48%), Positives = 89/127 (70%), Gaps = 1/127 (0%) Frame = +2 Query: 206 YMIWRETISSTSTLGFRIDGVKKADGTSSKDFKTTKTRQQIAEAFKDFTSSCPNAAVRYL 385 YM WRET+SST+T+GFRI+G+K+ADG+ +FK T+ ++Q+ A ++F N +YL Sbjct: 370 YMQWRETLSSTATMGFRIEGIKRADGSCDTNFKKTRCKEQVISALRNFVDGNKNILRKYL 429 Query: 386 ERLRSIRATLTESHFFRTHELIGSSLLFVHD-KRKASIWMIDFAKTVPVPENVSIDHNTT 562 RL+ +R L +S FF++HE++GSSLLFVHD +A +WMIDF KTV +P ++H T Sbjct: 430 VRLKELRTALEKSEFFQSHEVVGSSLLFVHDSSEQAKVWMIDFGKTVRLPCTQLLNHRTP 489 Query: 563 WKVGNHE 583 W GN E Sbjct: 490 WVEGNRE 496 Score = 74.5 bits (175), Expect = 2e-12 Identities = 32/57 (56%), Positives = 37/57 (64%) Frame = +1 Query: 34 PGVMDCKIGVRTYXXXXXXXXXXXXXXRKDMYEKMIQIDPKAPSEEEHRSKGVTKPR 204 P +MDCK+GVRTY RKDMYEKMI +DP AP+EEEHR K + KPR Sbjct: 313 PSIMDCKMGVRTYLEEELVKAKEKPKLRKDMYEKMIAVDPNAPTEEEHRQKAILKPR 369 >UniRef50_Q96DU7 Cluster: Inositol-trisphosphate 3-kinase C; n=7; Eutheria|Rep: Inositol-trisphosphate 3-kinase C - Homo sapiens (Human) Length = 683 Score = 137 bits (331), Expect = 2e-31 Identities = 63/127 (49%), Positives = 85/127 (66%), Gaps = 1/127 (0%) Frame = +2 Query: 206 YMIWRETISSTSTLGFRIDGVKKADGTSSKDFKTTKTRQQIAEAFKDFTSSCPNAAVRYL 385 YM WRET+SSTSTLGFRI+G+KKADGT + +FK T+ +Q+ + +DF +Y+ Sbjct: 537 YMQWRETMSSTSTLGFRIEGIKKADGTCNTNFKKTQALEQVTKVLEDFVDGDHVILQKYV 596 Query: 386 ERLRSIRATLTESHFFRTHELIGSSLLFVHDKR-KASIWMIDFAKTVPVPENVSIDHNTT 562 L +R L S FF+THE++GSSLLFVHD A +WMIDF KTV +P++ ++ H Sbjct: 597 ACLEELREALEISPFFKTHEVVGSSLLFVHDHTGLAKVWMIDFGKTVALPDHQTLSHRLP 656 Query: 563 WKVGNHE 583 W GN E Sbjct: 657 WAEGNRE 663 Score = 66.1 bits (154), Expect = 6e-10 Identities = 29/57 (50%), Positives = 34/57 (59%) Frame = +1 Query: 34 PGVMDCKIGVRTYXXXXXXXXXXXXXXRKDMYEKMIQIDPKAPSEEEHRSKGVTKPR 204 P +MDCK+G RTY RKDMYEKM+ +DP AP+ EEH VTKPR Sbjct: 480 PSIMDCKMGSRTYLEEELVKARERPRPRKDMYEKMVAVDPGAPTPEEHAQGAVTKPR 536 >UniRef50_Q8JFU9 Cluster: Novel protein similar to vertebrate inositol 1,4,5-triphosphate 3- kinase; n=8; Danio rerio|Rep: Novel protein similar to vertebrate inositol 1,4,5-triphosphate 3- kinase - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 298 Score = 134 bits (323), Expect = 2e-30 Identities = 59/127 (46%), Positives = 84/127 (66%), Gaps = 1/127 (0%) Frame = +2 Query: 206 YMIWRETISSTSTLGFRIDGVKKADGTSSKDFKTTKTRQQIAEAFKDFTSSCPNAAVRYL 385 YM WRE++SST TLGFRI+G+K+ + T + DFK T++++ + + FKDF N Y+ Sbjct: 152 YMQWRESLSSTHTLGFRIEGIKRGE-TCNTDFKKTRSKEDVTQVFKDFIEGNKNIINSYI 210 Query: 386 ERLRSIRATLTESHFFRTHELIGSSLLFVHD-KRKASIWMIDFAKTVPVPENVSIDHNTT 562 RL I+ L S FF+ HE+IGSSLLF+HD +A +W+IDF KT +P+ +DH Sbjct: 211 TRLEEIKRALKASEFFKKHEVIGSSLLFIHDHTERAEVWLIDFGKTTALPDGQYLDHYRP 270 Query: 563 WKVGNHE 583 W+ GN E Sbjct: 271 WEEGNRE 277 Score = 63.3 bits (147), Expect = 4e-09 Identities = 35/98 (35%), Positives = 50/98 (51%), Gaps = 2/98 (2%) Frame = +1 Query: 34 PGVMDCKIGVRTYXXXXXXXXXXXXXXRKDMYEKMIQIDPKAPSEEEHRSKGVTKPRVHD 213 P VMDCK+GVRTY R+D+Y KM+++D AP+ EE + K VTKPR Sbjct: 95 PNVMDCKMGVRTYLEDELVRARVKPKLREDLYNKMLEVDSGAPTAEERQQKAVTKPRYMQ 154 Query: 214 LEGDYQL--YLNFRLQDRRGEES*WNKF*RLQNHEDET 321 L FR++ + E+ F + ++ ED T Sbjct: 155 WRESLSSTHTLGFRIEGIKRGETCNTDFKKTRSKEDVT 192 >UniRef50_UPI0000F21BCC Cluster: PREDICTED: similar to inositol 1,4,5-trisphosphate 3-kinase,; n=2; Danio rerio|Rep: PREDICTED: similar to inositol 1,4,5-trisphosphate 3-kinase, - Danio rerio Length = 596 Score = 132 bits (318), Expect = 8e-30 Identities = 66/145 (45%), Positives = 91/145 (62%), Gaps = 1/145 (0%) Frame = +2 Query: 152 QKHLQKKSTEVKESRSQGYMIWRETISSTSTLGFRIDGVKKADGTSSKDFKTTKTRQQIA 331 ++H QK T+++ Y+ WR+ SSTS+LGFRI+G+ +G +DF T T Q+ Sbjct: 428 EEHEQKGITKLR------YLQWRDNSSSTSSLGFRIEGIVVGNGKVLRDFYKTCTEAQVT 481 Query: 332 EAFKDFTSSCPNAAVRYLERLRSIRATLTESHFFRTHELIGSSLLFVHDK-RKASIWMID 508 E FT + Y RL+++ TL +S FF HE+IGSSLLFVHD+ KA+IWMID Sbjct: 482 ETLLSFTRRQIHILEAYESRLQALYETLKQSSFFNKHEIIGSSLLFVHDRNNKANIWMID 541 Query: 509 FAKTVPVPENVSIDHNTTWKVGNHE 583 F KT+PVPE+V + H+ W GN E Sbjct: 542 FGKTIPVPEDVQLSHDVPWVEGNRE 566 Score = 67.3 bits (157), Expect = 2e-10 Identities = 28/57 (49%), Positives = 37/57 (64%) Frame = +1 Query: 34 PGVMDCKIGVRTYXXXXXXXXXXXXXXRKDMYEKMIQIDPKAPSEEEHRSKGVTKPR 204 P +MDCK+GVRTY R DMY+KM+++DP AP++EEH KG+TK R Sbjct: 383 PVIMDCKMGVRTYQEAEIIKARINPSVRTDMYQKMVKVDPAAPTDEEHEQKGITKLR 439 >UniRef50_Q95Q62 Cluster: Let-23 fertility effector/regulator protein 2, isoform a; n=7; Caenorhabditis|Rep: Let-23 fertility effector/regulator protein 2, isoform a - Caenorhabditis elegans Length = 494 Score = 118 bits (285), Expect = 8e-26 Identities = 56/127 (44%), Positives = 80/127 (62%), Gaps = 1/127 (0%) Frame = +2 Query: 206 YMIWRETISSTSTLGFRIDGVKKADGTSSKDFKTTKTRQQIAEAFKDFTSSCPNAAVRYL 385 YM +RE SST+ LGFRI+ K+ +G K+FK +T + + F DF + + + L Sbjct: 325 YMQFRERESSTAQLGFRIEAAKRLEGALEKNFKKVRTVEDVTTTFMDFFGTQRSRVRQQL 384 Query: 386 -ERLRSIRATLTESHFFRTHELIGSSLLFVHDKRKASIWMIDFAKTVPVPENVSIDHNTT 562 ERL+S+R + S FF +HE++GSS+L V D K WMIDFAK+ PVP +++H TT Sbjct: 385 IERLKSMRKAIEHSSFFNSHEVVGSSILIVFDTEKVGCWMIDFAKSSPVPNGRTLNHRTT 444 Query: 563 WKVGNHE 583 W GN+E Sbjct: 445 WIPGNNE 451 Score = 41.5 bits (93), Expect = 0.014 Identities = 22/55 (40%), Positives = 29/55 (52%) Frame = +1 Query: 40 VMDCKIGVRTYXXXXXXXXXXXXXXRKDMYEKMIQIDPKAPSEEEHRSKGVTKPR 204 +MD KIG RT+ R D+YEKM+ ID P+EEE + +TK R Sbjct: 274 IMDIKIGTRTFLESEVSNTKK----RADLYEKMVAIDNDEPTEEERKCGAITKLR 324 >UniRef50_Q9VL83 Cluster: CG4026-PA; n=5; Diptera|Rep: CG4026-PA - Drosophila melanogaster (Fruit fly) Length = 441 Score = 108 bits (260), Expect = 8e-23 Identities = 47/126 (37%), Positives = 79/126 (62%) Frame = +2 Query: 206 YMIWRETISSTSTLGFRIDGVKKADGTSSKDFKTTKTRQQIAEAFKDFTSSCPNAAVRYL 385 YM +RE++SS+ + GFRI+ ++ KD KT ++ +QIA+ + F ++ + L Sbjct: 286 YMTFRESLSSSHSKGFRIEALRLRGRPPVKDLKTCRSSEQIAQTIEQFLAARRSVQKELL 345 Query: 386 ERLRSIRATLTESHFFRTHELIGSSLLFVHDKRKASIWMIDFAKTVPVPENVSIDHNTTW 565 +RL+ +R + +S FF +HE+IGSS+ V+D + +W+IDFAK +P +V +DH + W Sbjct: 346 KRLKHMRLVIEQSTFFASHEIIGSSIFIVYDDDRVGVWLIDFAKCRELPPHVRVDHRSAW 405 Query: 566 KVGNHE 583 GN E Sbjct: 406 APGNRE 411 Score = 42.3 bits (95), Expect = 0.008 Identities = 22/57 (38%), Positives = 31/57 (54%) Frame = +1 Query: 34 PGVMDCKIGVRTYXXXXXXXXXXXXXXRKDMYEKMIQIDPKAPSEEEHRSKGVTKPR 204 P VMD K+G RT+ R D+Y+KMI +D AP+ EH ++ +TK R Sbjct: 233 PCVMDIKMGSRTFLESEVSNATL----RPDLYQKMIAVDAGAPTPAEHEARAITKLR 285 >UniRef50_A3EXV5 Cluster: Inositol 1,4,5-triphosphate kinase 1-like protein; n=3; Neoptera|Rep: Inositol 1,4,5-triphosphate kinase 1-like protein - Maconellicoccus hirsutus (hibiscus mealybug) Length = 185 Score = 108 bits (259), Expect = 1e-22 Identities = 52/126 (41%), Positives = 72/126 (57%) Frame = +2 Query: 206 YMIWRETISSTSTLGFRIDGVKKADGTSSKDFKTTKTRQQIAEAFKDFTSSCPNAAVRYL 385 YM +RE SSTSTLGFRI+ ++ D K K Q++ + F + R Sbjct: 24 YMQFREEQSSTSTLGFRIEAMEFRGSKPVTDLKKVKNSQEVCDTLSLFFGDREDIRQRLA 83 Query: 386 ERLRSIRATLTESHFFRTHELIGSSLLFVHDKRKASIWMIDFAKTVPVPENVSIDHNTTW 565 RL IRA L +S +F+ HE++GSS+L ++D K W+IDFAKT PVP + ++ H W Sbjct: 84 TRLIEIRARLEQSLYFKKHEVVGSSILIIYDDVKVGAWLIDFAKTRPVPSDKNLTHRLPW 143 Query: 566 KVGNHE 583 GNHE Sbjct: 144 SPGNHE 149 Score = 33.9 bits (74), Expect = 2.8 Identities = 14/23 (60%), Positives = 17/23 (73%) Frame = +1 Query: 136 MIQIDPKAPSEEEHRSKGVTKPR 204 MI +DP AP+ EEH +K VTK R Sbjct: 1 MIAVDPSAPTAEEHAAKAVTKLR 23 >UniRef50_Q5DHU6 Cluster: SJCHGC06700 protein; n=1; Schistosoma japonicum|Rep: SJCHGC06700 protein - Schistosoma japonicum (Blood fluke) Length = 308 Score = 107 bits (258), Expect = 1e-22 Identities = 55/130 (42%), Positives = 77/130 (59%), Gaps = 4/130 (3%) Frame = +2 Query: 206 YMIWRETISSTSTLGFRIDGVKKADGTSSKDFKTTKTRQQIAEAFKDFTSSCPNAAVRYL 385 Y+ WR+TISST+ GFRI+ +K ++ +DF+ T+ +I K F A YL Sbjct: 157 YLQWRDTISSTAEFGFRIEAIKLPSESTRRDFQHTRKWDEIINHCKLFIQGRKIIAQNYL 216 Query: 386 ERLRSIRATLTESHFFRTHELIGSSLLFVHDKR-KASIWMIDFAKTV---PVPENVSIDH 553 RL +R L S FF HE IGSSLLFVHD+ A+IW+IDFAK P+ + ++H Sbjct: 217 LRLLKLRTILEVSDFFAKHEFIGSSLLFVHDESGYANIWLIDFAKVTSPSPLDHKIRVNH 276 Query: 554 NTTWKVGNHE 583 + W+ GN+E Sbjct: 277 RSKWQCGNYE 286 Score = 57.6 bits (133), Expect = 2e-07 Identities = 29/57 (50%), Positives = 32/57 (56%) Frame = +1 Query: 34 PGVMDCKIGVRTYXXXXXXXXXXXXXXRKDMYEKMIQIDPKAPSEEEHRSKGVTKPR 204 P VMDCKIG RTY RKD+Y KMI P P+E EHR KGV+K R Sbjct: 101 PSVMDCKIGQRTYSESEVIADSSENF-RKDLYLKMISTSPNVPTEREHREKGVSKLR 156 >UniRef50_UPI0001556459 Cluster: PREDICTED: similar to Inositol 1,4,5-trisphosphate 3-kinase A, partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to Inositol 1,4,5-trisphosphate 3-kinase A, partial - Ornithorhynchus anatinus Length = 473 Score = 67.3 bits (157), Expect = 2e-10 Identities = 29/57 (50%), Positives = 37/57 (64%) Frame = +1 Query: 34 PGVMDCKIGVRTYXXXXXXXXXXXXXXRKDMYEKMIQIDPKAPSEEEHRSKGVTKPR 204 P V+DCK+GVRTY RKDMY+KM+++DP AP+ EEH + VTKPR Sbjct: 185 PCVLDCKMGVRTYLEEELSKARERPKLRKDMYKKMLEVDPGAPTAEEHAQRAVTKPR 241 Score = 41.5 bits (93), Expect = 0.014 Identities = 17/26 (65%), Positives = 22/26 (84%) Frame = +2 Query: 206 YMIWRETISSTSTLGFRIDGVKKADG 283 YM WRE+ISS++TLGFRI+G+K G Sbjct: 242 YMQWRESISSSTTLGFRIEGIKGPTG 267 >UniRef50_UPI00015B4C69 Cluster: PREDICTED: similar to inositol triphosphate 3-kinase c; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to inositol triphosphate 3-kinase c - Nasonia vitripennis Length = 310 Score = 61.3 bits (142), Expect = 2e-08 Identities = 23/49 (46%), Positives = 31/49 (63%) Frame = +2 Query: 437 THELIGSSLLFVHDKRKASIWMIDFAKTVPVPENVSIDHNTTWKVGNHE 583 T +IGSS+ ++D K +W+IDFAKT VPE + H W+ GNHE Sbjct: 243 TSNVIGSSIFMIYDNEKVGVWLIDFAKTYEVPEGCKLTHRREWQQGNHE 291 >UniRef50_A2ELN6 Cluster: Putative uncharacterized protein; n=1; Trichomonas vaginalis G3|Rep: Putative uncharacterized protein - Trichomonas vaginalis G3 Length = 291 Score = 33.9 bits (74), Expect = 2.8 Identities = 24/87 (27%), Positives = 45/87 (51%), Gaps = 6/87 (6%) Frame = +2 Query: 278 DGTSS---KDFKTTKTRQQIAEAFKDFTSSCPNAAVRYLERLRSIRATLTESHFFRTHEL 448 DG +S +DF TT T++++ + F DF + +++++++ I +T + Sbjct: 170 DGDASLLKRDFGTTCTKEELMKFFSDF-FHVKDLVPKFIDKIKKIIEGITILRQEADVRI 228 Query: 449 IGSSLLFVHDKRKASIW---MIDFAKT 520 SS LFV+D S + ++DF KT Sbjct: 229 YSSSALFVYDAEDPSKFDCRLLDFEKT 255 >UniRef50_A6CXX6 Cluster: YkgB; n=1; Vibrio shilonii AK1|Rep: YkgB - Vibrio shilonii AK1 Length = 393 Score = 33.5 bits (73), Expect = 3.8 Identities = 13/26 (50%), Positives = 17/26 (65%) Frame = -2 Query: 508 IYHPNGSFPFVMNEQQRTPDQFVCSE 431 + HPNG F FV+NE T D F+ +E Sbjct: 227 VNHPNGQFAFVLNELSSTLDVFIVNE 252 >UniRef50_Q4N2C0 Cluster: Putative uncharacterized protein; n=2; Theileria|Rep: Putative uncharacterized protein - Theileria parva Length = 601 Score = 33.1 bits (72), Expect = 5.0 Identities = 23/80 (28%), Positives = 39/80 (48%), Gaps = 1/80 (1%) Frame = +2 Query: 152 QKHLQKKSTEVKESRSQGYMIWRETISSTSTLGFRIDGVKKADGTSSKDFKTTKTRQ-QI 328 +KH + KS ++K S++ I +T+S S R + K+D KDF+ ++ Q Sbjct: 11 KKHSKDKSKKIKVSKNLIKNINHDTVSKDSVTKPRKIKI-KSDKVRKKDFENVNIKKFQT 69 Query: 329 AEAFKDFTSSCPNAAVRYLE 388 E +K + S A+ Y E Sbjct: 70 LEEYKSYISQICTQAITYPE 89 >UniRef50_Q39VQ4 Cluster: Putative uncharacterized protein; n=3; Desulfuromonadales|Rep: Putative uncharacterized protein - Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210) Length = 448 Score = 32.7 bits (71), Expect = 6.6 Identities = 17/50 (34%), Positives = 27/50 (54%) Frame = +2 Query: 350 TSSCPNAAVRYLERLRSIRATLTESHFFRTHELIGSSLLFVHDKRKASIW 499 T + P+ A RYL +L + T+T+ F +H+ +L H RK+S W Sbjct: 396 TKTYPHGA-RYLRKLDKLAGTITDWRTFESHDFYKENLRLNHG-RKSSFW 443 >UniRef50_A6C743 Cluster: Putative uncharacterized protein; n=1; Planctomyces maris DSM 8797|Rep: Putative uncharacterized protein - Planctomyces maris DSM 8797 Length = 233 Score = 32.7 bits (71), Expect = 6.6 Identities = 16/47 (34%), Positives = 28/47 (59%), Gaps = 1/47 (2%) Frame = -1 Query: 218 SRSCTLGFVTPLL-LCSSSEGAFGSIWIIFSYISFLNLVFSFALANS 81 S +C +GFV L+ L + F ++W+ S I+F L+FS+ ++ S Sbjct: 16 SAACLIGFVLALVTLLAIETKRFRAVWLFCSLITFCFLLFSYEISAS 62 >UniRef50_UPI00006CE914 Cluster: hypothetical protein TTHERM_00559890; n=1; Tetrahymena thermophila SB210|Rep: hypothetical protein TTHERM_00559890 - Tetrahymena thermophila SB210 Length = 467 Score = 32.3 bits (70), Expect = 8.7 Identities = 20/70 (28%), Positives = 32/70 (45%) Frame = +2 Query: 221 ETISSTSTLGFRIDGVKKADGTSSKDFKTTKTRQQIAEAFKDFTSSCPNAAVRYLERLRS 400 + + S+S+ G I+G S + QQI + + FT CPN RY+ L S Sbjct: 382 QNLFSSSSFGIFINGFA-CFKLSYLTLVNSTLPQQINSSLQVFTDQCPNQTFRYINFLYS 440 Query: 401 IRATLTESHF 430 I T ++ + Sbjct: 441 IITTSSQDQY 450 >UniRef50_Q82Z99 Cluster: HD/KH domain protein; n=11; Bacilli|Rep: HD/KH domain protein - Enterococcus faecalis (Streptococcus faecalis) Length = 518 Score = 32.3 bits (70), Expect = 8.7 Identities = 23/98 (23%), Positives = 45/98 (45%) Frame = +2 Query: 152 QKHLQKKSTEVKESRSQGYMIWRETISSTSTLGFRIDGVKKADGTSSKDFKTTKTRQQIA 331 QK+ + +E+KESR + I TL + D ++K +G+ + + RQQ+ Sbjct: 65 QKYRSEIESELKESRLELKSQENRLIQREQTLDRKDDSLEKREGSLEEKEEKLGARQQLI 124 Query: 332 EAFKDFTSSCPNAAVRYLERLRSIRATLTESHFFRTHE 445 + + + N + LER+ S+ +S ++ E Sbjct: 125 DEREKEVENLINQQHQELERIASLSKEEAKSIIMKSTE 162 >UniRef50_A6RXF1 Cluster: Putative uncharacterized protein; n=3; Sclerotiniaceae|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 932 Score = 32.3 bits (70), Expect = 8.7 Identities = 15/54 (27%), Positives = 25/54 (46%) Frame = -3 Query: 318 LVFVVLKSLELVPSAFFTPSILKPKVEVELIVSLQIMYPWLRDSFTSVLFF*RC 157 ++ +L+ L L+ A+FT I K + + L PWLR + + F C Sbjct: 81 IICAILRQLHLIVQAYFTSEISNLKPDAFFVDQLSAGLPWLRYFYPNTRIFFYC 134 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 540,680,213 Number of Sequences: 1657284 Number of extensions: 9736071 Number of successful extensions: 29181 Number of sequences better than 10.0: 27 Number of HSP's better than 10.0 without gapping: 28409 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 29161 length of database: 575,637,011 effective HSP length: 96 effective length of database: 416,537,747 effective search space used: 40820699206 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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