Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= P5PG0587
(584 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Y18024-1|CAB65055.3| 946|Homo sapiens inositol 1,4,5-trisphosph... 169 5e-42
X57206-1|CAA40491.1| 472|Homo sapiens 1D-myo-inositol-trisphosp... 169 5e-42
AY513281-1|AAT08034.1| 472|Homo sapiens proliferation-inducing ... 169 5e-42
AL365444-3|CAH70188.1| 946|Homo sapiens inositol 1,4,5-trisphos... 169 5e-42
AJ242780-1|CAC40650.1| 946|Homo sapiens inositol 1,4,5-trisphos... 169 5e-42
X54938-1|CAA38700.1| 461|Homo sapiens inositol 1,4,5-triphospha... 155 1e-37
BC026331-1|AAH26331.1| 461|Homo sapiens inositol 1,4,5-trisphos... 155 1e-37
Y11999-1|CAA72728.1| 137|Homo sapiens inositol 1,4,5-trisphosph... 137 3e-32
D38169-1|BAA22524.1| 604|Homo sapiens inositol 1,4,5-trisphosph... 137 3e-32
BC060788-1|AAH60788.1| 683|Homo sapiens inositol 1,4,5-trisphos... 137 3e-32
AJ290975-1|CAC40815.1| 683|Homo sapiens inositol 1,4,5-trisphos... 137 3e-32
AK023227-1|BAB14478.1| 744|Homo sapiens protein ( Homo sapiens ... 30 5.2
>Y18024-1|CAB65055.3| 946|Homo sapiens inositol 1,4,5-trisphosphate
3-kinase B protein.
Length = 946
Score = 169 bits (412), Expect = 5e-42
Identities = 74/127 (58%), Positives = 98/127 (77%), Gaps = 1/127 (0%)
Frame = +2
Query: 206 YMIWRETISSTSTLGFRIDGVKKADGTSSKDFKTTKTRQQIAEAFKDFTSSCPNAAVRYL 385
YM WRETISST+TLGFRI+G+KK DGT ++DFK TKTR+Q+ EAF++FT N + Y
Sbjct: 796 YMQWRETISSTATLGFRIEGIKKEDGTVNRDFKKTKTREQVTEAFREFTKGNHNILIAYR 855
Query: 386 ERLRSIRATLTESHFFRTHELIGSSLLFVHDKR-KASIWMIDFAKTVPVPENVSIDHNTT 562
+RL++IR TL S FF+ HE+IGSSLLF+HDK+ +A +WMIDF KT P+PE ++ H+
Sbjct: 856 DRLKAIRTTLEVSPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGKTTPLPEGQTLQHDVP 915
Query: 563 WKVGNHE 583
W+ GN E
Sbjct: 916 WQEGNRE 922
Score = 69.3 bits (162), Expect = 9e-12
Identities = 30/57 (52%), Positives = 38/57 (66%)
Frame = +1
Query: 34 PGVMDCKIGVRTYXXXXXXXXXXXXXXRKDMYEKMIQIDPKAPSEEEHRSKGVTKPR 204
P VMDCK+G+RTY RKDMY+KMI++DP+AP+EEE + VTKPR
Sbjct: 739 PCVMDCKMGIRTYLEEELTKARKKPSLRKDMYQKMIEVDPEAPTEEEKAQRAVTKPR 795
>X57206-1|CAA40491.1| 472|Homo sapiens
1D-myo-inositol-trisphosphate 3-kinase protein.
Length = 472
Score = 169 bits (412), Expect = 5e-42
Identities = 74/127 (58%), Positives = 98/127 (77%), Gaps = 1/127 (0%)
Frame = +2
Query: 206 YMIWRETISSTSTLGFRIDGVKKADGTSSKDFKTTKTRQQIAEAFKDFTSSCPNAAVRYL 385
YM WRETISST+TLGFRI+G+KK DGT ++DFK TKTR+Q+ EAF++FT N + Y
Sbjct: 322 YMQWRETISSTATLGFRIEGIKKEDGTVNRDFKKTKTREQVTEAFREFTKGNHNILIAYR 381
Query: 386 ERLRSIRATLTESHFFRTHELIGSSLLFVHDKR-KASIWMIDFAKTVPVPENVSIDHNTT 562
+RL++IR TL S FF+ HE+IGSSLLF+HDK+ +A +WMIDF KT P+PE ++ H+
Sbjct: 382 DRLKAIRTTLEVSPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGKTTPLPEGQTLQHDVP 441
Query: 563 WKVGNHE 583
W+ GN E
Sbjct: 442 WQEGNRE 448
Score = 69.3 bits (162), Expect = 9e-12
Identities = 30/57 (52%), Positives = 38/57 (66%)
Frame = +1
Query: 34 PGVMDCKIGVRTYXXXXXXXXXXXXXXRKDMYEKMIQIDPKAPSEEEHRSKGVTKPR 204
P VMDCK+G+RTY RKDMY+KMI++DP+AP+EEE + VTKPR
Sbjct: 265 PCVMDCKMGIRTYLEEELTKARKKPSLRKDMYQKMIEVDPEAPTEEEKAQRAVTKPR 321
>AY513281-1|AAT08034.1| 472|Homo sapiens proliferation-inducing
protein 37 protein.
Length = 472
Score = 169 bits (412), Expect = 5e-42
Identities = 74/127 (58%), Positives = 98/127 (77%), Gaps = 1/127 (0%)
Frame = +2
Query: 206 YMIWRETISSTSTLGFRIDGVKKADGTSSKDFKTTKTRQQIAEAFKDFTSSCPNAAVRYL 385
YM WRETISST+TLGFRI+G+KK DGT ++DFK TKTR+Q+ EAF++FT N + Y
Sbjct: 322 YMQWRETISSTATLGFRIEGIKKEDGTVNRDFKKTKTREQVTEAFREFTKGNHNILIAYR 381
Query: 386 ERLRSIRATLTESHFFRTHELIGSSLLFVHDKR-KASIWMIDFAKTVPVPENVSIDHNTT 562
+RL++IR TL S FF+ HE+IGSSLLF+HDK+ +A +WMIDF KT P+PE ++ H+
Sbjct: 382 DRLKAIRTTLEVSPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGKTTPLPEGQTLQHDVP 441
Query: 563 WKVGNHE 583
W+ GN E
Sbjct: 442 WQEGNRE 448
Score = 69.3 bits (162), Expect = 9e-12
Identities = 30/57 (52%), Positives = 38/57 (66%)
Frame = +1
Query: 34 PGVMDCKIGVRTYXXXXXXXXXXXXXXRKDMYEKMIQIDPKAPSEEEHRSKGVTKPR 204
P VMDCK+G+RTY RKDMY+KMI++DP+AP+EEE + VTKPR
Sbjct: 265 PCVMDCKMGIRTYLEEELTKARKKPSLRKDMYQKMIEVDPEAPTEEEKAQRAVTKPR 321
>AL365444-3|CAH70188.1| 946|Homo sapiens inositol 1,4,5-trisphosphate
3-kinase B protein.
Length = 946
Score = 169 bits (412), Expect = 5e-42
Identities = 74/127 (58%), Positives = 98/127 (77%), Gaps = 1/127 (0%)
Frame = +2
Query: 206 YMIWRETISSTSTLGFRIDGVKKADGTSSKDFKTTKTRQQIAEAFKDFTSSCPNAAVRYL 385
YM WRETISST+TLGFRI+G+KK DGT ++DFK TKTR+Q+ EAF++FT N + Y
Sbjct: 796 YMQWRETISSTATLGFRIEGIKKEDGTVNRDFKKTKTREQVTEAFREFTKGNHNILIAYR 855
Query: 386 ERLRSIRATLTESHFFRTHELIGSSLLFVHDKR-KASIWMIDFAKTVPVPENVSIDHNTT 562
+RL++IR TL S FF+ HE+IGSSLLF+HDK+ +A +WMIDF KT P+PE ++ H+
Sbjct: 856 DRLKAIRTTLEVSPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGKTTPLPEGQTLQHDVP 915
Query: 563 WKVGNHE 583
W+ GN E
Sbjct: 916 WQEGNRE 922
Score = 69.3 bits (162), Expect = 9e-12
Identities = 30/57 (52%), Positives = 38/57 (66%)
Frame = +1
Query: 34 PGVMDCKIGVRTYXXXXXXXXXXXXXXRKDMYEKMIQIDPKAPSEEEHRSKGVTKPR 204
P VMDCK+G+RTY RKDMY+KMI++DP+AP+EEE + VTKPR
Sbjct: 739 PCVMDCKMGIRTYLEEELTKARKKPSLRKDMYQKMIEVDPEAPTEEEKAQRAVTKPR 795
>AJ242780-1|CAC40650.1| 946|Homo sapiens inositol 1,4,5-trisphosphate
3-kinase, isoform B protein.
Length = 946
Score = 169 bits (412), Expect = 5e-42
Identities = 74/127 (58%), Positives = 98/127 (77%), Gaps = 1/127 (0%)
Frame = +2
Query: 206 YMIWRETISSTSTLGFRIDGVKKADGTSSKDFKTTKTRQQIAEAFKDFTSSCPNAAVRYL 385
YM WRETISST+TLGFRI+G+KK DGT ++DFK TKTR+Q+ EAF++FT N + Y
Sbjct: 796 YMQWRETISSTATLGFRIEGIKKEDGTVNRDFKKTKTREQVTEAFREFTKGNHNILIAYR 855
Query: 386 ERLRSIRATLTESHFFRTHELIGSSLLFVHDKR-KASIWMIDFAKTVPVPENVSIDHNTT 562
+RL++IR TL S FF+ HE+IGSSLLF+HDK+ +A +WMIDF KT P+PE ++ H+
Sbjct: 856 DRLKAIRTTLEVSPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGKTTPLPEGQTLQHDVP 915
Query: 563 WKVGNHE 583
W+ GN E
Sbjct: 916 WQEGNRE 922
Score = 69.3 bits (162), Expect = 9e-12
Identities = 30/57 (52%), Positives = 38/57 (66%)
Frame = +1
Query: 34 PGVMDCKIGVRTYXXXXXXXXXXXXXXRKDMYEKMIQIDPKAPSEEEHRSKGVTKPR 204
P VMDCK+G+RTY RKDMY+KMI++DP+AP+EEE + VTKPR
Sbjct: 739 PCVMDCKMGIRTYLEEELTKARKKPSLRKDMYQKMIEVDPEAPTEEEKAQRAVTKPR 795
>X54938-1|CAA38700.1| 461|Homo sapiens inositol 1,4,5-triphosphate
3-kinase protein.
Length = 461
Score = 155 bits (376), Expect = 1e-37
Identities = 70/127 (55%), Positives = 90/127 (70%), Gaps = 1/127 (0%)
Frame = +2
Query: 206 YMIWRETISSTSTLGFRIDGVKKADGTSSKDFKTTKTRQQIAEAFKDFTSSCPNAAVRYL 385
YM WRE ISS++TLGFRI+G+KKADG+ S DFKTT++R+Q+ F++F RYL
Sbjct: 315 YMQWREGISSSTTLGFRIEGIKKADGSCSTDFKTTRSREQVLRVFEEFVQGDEEVLRRYL 374
Query: 386 ERLRSIRATLTESHFFRTHELIGSSLLFVHDK-RKASIWMIDFAKTVPVPENVSIDHNTT 562
RL+ IR TL S FFR HE+IGSSLLFVHD +A +W+IDF KT P+P+ +DH
Sbjct: 375 NRLQQIRDTLEVSEFFRRHEVIGSSLLFVHDHCHRAGVWLIDFGKTTPLPDGQILDHRRP 434
Query: 563 WKVGNHE 583
W+ GN E
Sbjct: 435 WEEGNRE 441
Score = 69.7 bits (163), Expect = 7e-12
Identities = 30/57 (52%), Positives = 38/57 (66%)
Frame = +1
Query: 34 PGVMDCKIGVRTYXXXXXXXXXXXXXXRKDMYEKMIQIDPKAPSEEEHRSKGVTKPR 204
P V+DCK+GVRTY RKDMY+KM+ +DP+AP+EEEH + VTKPR
Sbjct: 258 PCVLDCKMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAPTEEEHAQRAVTKPR 314
>BC026331-1|AAH26331.1| 461|Homo sapiens inositol
1,4,5-trisphosphate 3-kinase A protein.
Length = 461
Score = 155 bits (376), Expect = 1e-37
Identities = 70/127 (55%), Positives = 90/127 (70%), Gaps = 1/127 (0%)
Frame = +2
Query: 206 YMIWRETISSTSTLGFRIDGVKKADGTSSKDFKTTKTRQQIAEAFKDFTSSCPNAAVRYL 385
YM WRE ISS++TLGFRI+G+KKADG+ S DFKTT++R+Q+ F++F RYL
Sbjct: 315 YMQWREGISSSTTLGFRIEGIKKADGSCSTDFKTTRSREQVLRVFEEFVQGDEEVLRRYL 374
Query: 386 ERLRSIRATLTESHFFRTHELIGSSLLFVHDK-RKASIWMIDFAKTVPVPENVSIDHNTT 562
RL+ IR TL S FFR HE+IGSSLLFVHD +A +W+IDF KT P+P+ +DH
Sbjct: 375 NRLQQIRDTLEVSEFFRRHEVIGSSLLFVHDHCHRAGVWLIDFGKTTPLPDGQILDHRRP 434
Query: 563 WKVGNHE 583
W+ GN E
Sbjct: 435 WEEGNRE 441
Score = 69.7 bits (163), Expect = 7e-12
Identities = 30/57 (52%), Positives = 38/57 (66%)
Frame = +1
Query: 34 PGVMDCKIGVRTYXXXXXXXXXXXXXXRKDMYEKMIQIDPKAPSEEEHRSKGVTKPR 204
P V+DCK+GVRTY RKDMY+KM+ +DP+AP+EEEH + VTKPR
Sbjct: 258 PCVLDCKMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAPTEEEHAQRAVTKPR 314
>Y11999-1|CAA72728.1| 137|Homo sapiens inositol 1,4,5-trisphosphate
3-kinase protein.
Length = 137
Score = 137 bits (331), Expect = 3e-32
Identities = 63/127 (49%), Positives = 85/127 (66%), Gaps = 1/127 (0%)
Frame = +2
Query: 206 YMIWRETISSTSTLGFRIDGVKKADGTSSKDFKTTKTRQQIAEAFKDFTSSCPNAAVRYL 385
YM WRET+SSTSTLGFRI+G+KKADGT + +FK T+ +Q+ + +DF +Y+
Sbjct: 7 YMQWRETMSSTSTLGFRIEGIKKADGTCNTNFKKTQALEQVTKVLEDFVDGDHVILQKYV 66
Query: 386 ERLRSIRATLTESHFFRTHELIGSSLLFVHDKR-KASIWMIDFAKTVPVPENVSIDHNTT 562
L +R L S FF+THE++GSSLLFVHD A +WMIDF KTV +P++ ++ H
Sbjct: 67 ACLEELREALEISPFFKTHEVVGSSLLFVHDHTGLAKVWMIDFGKTVALPDHQTLSHRLP 126
Query: 563 WKVGNHE 583
W GN E
Sbjct: 127 WAEGNRE 133
>D38169-1|BAA22524.1| 604|Homo sapiens inositol 1,4,5-trisphosphate
3-kinase isoenzyme protein.
Length = 604
Score = 137 bits (331), Expect = 3e-32
Identities = 63/127 (49%), Positives = 85/127 (66%), Gaps = 1/127 (0%)
Frame = +2
Query: 206 YMIWRETISSTSTLGFRIDGVKKADGTSSKDFKTTKTRQQIAEAFKDFTSSCPNAAVRYL 385
YM WRET+SSTSTLGFRI+G+KKADGT + +FK T+ +Q+ + +DF +Y+
Sbjct: 458 YMQWRETMSSTSTLGFRIEGIKKADGTCNTNFKKTQALEQVTKVLEDFVDGDHVILQKYV 517
Query: 386 ERLRSIRATLTESHFFRTHELIGSSLLFVHDKR-KASIWMIDFAKTVPVPENVSIDHNTT 562
L +R L S FF+THE++GSSLLFVHD A +WMIDF KTV +P++ ++ H
Sbjct: 518 ACLEELREALEISPFFKTHEVVGSSLLFVHDHTGLAKVWMIDFGKTVALPDHQTLSHRLP 577
Query: 563 WKVGNHE 583
W GN E
Sbjct: 578 WAEGNRE 584
Score = 66.1 bits (154), Expect = 9e-11
Identities = 29/57 (50%), Positives = 34/57 (59%)
Frame = +1
Query: 34 PGVMDCKIGVRTYXXXXXXXXXXXXXXRKDMYEKMIQIDPKAPSEEEHRSKGVTKPR 204
P +MDCK+G RTY RKDMYEKM+ +DP AP+ EEH VTKPR
Sbjct: 401 PSIMDCKMGSRTYLEEELVKARERPRPRKDMYEKMVAVDPGAPTPEEHAQGAVTKPR 457
>BC060788-1|AAH60788.1| 683|Homo sapiens inositol
1,4,5-trisphosphate 3-kinase C protein.
Length = 683
Score = 137 bits (331), Expect = 3e-32
Identities = 63/127 (49%), Positives = 85/127 (66%), Gaps = 1/127 (0%)
Frame = +2
Query: 206 YMIWRETISSTSTLGFRIDGVKKADGTSSKDFKTTKTRQQIAEAFKDFTSSCPNAAVRYL 385
YM WRET+SSTSTLGFRI+G+KKADGT + +FK T+ +Q+ + +DF +Y+
Sbjct: 537 YMQWRETMSSTSTLGFRIEGIKKADGTCNTNFKKTQALEQVTKVLEDFVDGDHVILQKYV 596
Query: 386 ERLRSIRATLTESHFFRTHELIGSSLLFVHDKR-KASIWMIDFAKTVPVPENVSIDHNTT 562
L +R L S FF+THE++GSSLLFVHD A +WMIDF KTV +P++ ++ H
Sbjct: 597 ACLEELREALEISPFFKTHEVVGSSLLFVHDHTGLAKVWMIDFGKTVALPDHQTLSHRLP 656
Query: 563 WKVGNHE 583
W GN E
Sbjct: 657 WAEGNRE 663
Score = 66.1 bits (154), Expect = 9e-11
Identities = 29/57 (50%), Positives = 34/57 (59%)
Frame = +1
Query: 34 PGVMDCKIGVRTYXXXXXXXXXXXXXXRKDMYEKMIQIDPKAPSEEEHRSKGVTKPR 204
P +MDCK+G RTY RKDMYEKM+ +DP AP+ EEH VTKPR
Sbjct: 480 PSIMDCKMGSRTYLEEELVKARERPRPRKDMYEKMVAVDPGAPTPEEHAQGAVTKPR 536
>AJ290975-1|CAC40815.1| 683|Homo sapiens inositol
1,4,5-trisphosphate 3-kinase C protein.
Length = 683
Score = 137 bits (331), Expect = 3e-32
Identities = 63/127 (49%), Positives = 85/127 (66%), Gaps = 1/127 (0%)
Frame = +2
Query: 206 YMIWRETISSTSTLGFRIDGVKKADGTSSKDFKTTKTRQQIAEAFKDFTSSCPNAAVRYL 385
YM WRET+SSTSTLGFRI+G+KKADGT + +FK T+ +Q+ + +DF +Y+
Sbjct: 537 YMQWRETMSSTSTLGFRIEGIKKADGTCNTNFKKTQALEQVTKVLEDFVDGDHVILQKYV 596
Query: 386 ERLRSIRATLTESHFFRTHELIGSSLLFVHDKR-KASIWMIDFAKTVPVPENVSIDHNTT 562
L +R L S FF+THE++GSSLLFVHD A +WMIDF KTV +P++ ++ H
Sbjct: 597 ACLEELREALEISPFFKTHEVVGSSLLFVHDHTGLAKVWMIDFGKTVALPDHQTLSHRLP 656
Query: 563 WKVGNHE 583
W GN E
Sbjct: 657 WAEGNRE 663
Score = 66.1 bits (154), Expect = 9e-11
Identities = 29/57 (50%), Positives = 34/57 (59%)
Frame = +1
Query: 34 PGVMDCKIGVRTYXXXXXXXXXXXXXXRKDMYEKMIQIDPKAPSEEEHRSKGVTKPR 204
P +MDCK+G RTY RKDMYEKM+ +DP AP+ EEH VTKPR
Sbjct: 480 PSIMDCKMGSRTYLEEELVKARERPRPRKDMYEKMVAVDPGAPTPEEHAQGAVTKPR 536
>AK023227-1|BAB14478.1| 744|Homo sapiens protein ( Homo sapiens
cDNA FLJ13165 fis, clone NT2RP3003686. ).
Length = 744
Score = 30.3 bits (65), Expect = 5.2
Identities = 15/47 (31%), Positives = 26/47 (55%)
Frame = +2
Query: 263 GVKKADGTSSKDFKTTKTRQQIAEAFKDFTSSCPNAAVRYLERLRSI 403
G +K +GT T + ++ AF+ FTS +A +++L RL+ I
Sbjct: 10 GAEKHEGTGQSSGITDQEKELSTNAFQAFTSGNYDACLQHLARLQDI 56
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 77,645,905
Number of Sequences: 237096
Number of extensions: 1453190
Number of successful extensions: 4129
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 3965
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4118
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 6098631048
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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