Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= P5PG0343
(544 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9W4T4 Cluster: cAMP-specific 3',5'-cyclic phosphodiest... 351 8e-96
UniRef50_Q13945 Cluster: 3',5'-cyclic AMP phosphodiesterase; n=3... 309 2e-83
UniRef50_P27815 Cluster: cAMP-specific 3',5'-cyclic phosphodiest... 307 1e-82
UniRef50_O43851 Cluster: PDE4C-delta109; n=18; Bilateria|Rep: PD... 302 3e-81
UniRef50_UPI000065D378 Cluster: cAMP-specific 3',5'-cyclic phosp... 263 1e-76
UniRef50_Q4SP32 Cluster: Chromosome 15 SCAF14542, whole genome s... 285 3e-76
UniRef50_Q22000 Cluster: Probable 3',5'-cyclic phosphodiesterase... 268 6e-71
UniRef50_Q3UEI1-2 Cluster: Isoform 2 of Q3UEI1 ; n=1; Mus muscul... 131 3e-57
UniRef50_O96078 Cluster: EFPDE4; n=1; Ephydatia fluviatilis|Rep:... 194 1e-48
UniRef50_Q005X2 Cluster: Phosphodiesterase 1; n=1; Strongylocent... 130 3e-29
UniRef50_UPI0000DB7125 Cluster: PREDICTED: similar to Phosphodie... 125 6e-28
UniRef50_UPI00006CBCA5 Cluster: 3''''5''''-cyclic nucleotide pho... 123 3e-27
UniRef50_A4RV03 Cluster: Predicted protein; n=1; Ostreococcus lu... 122 5e-27
UniRef50_UPI000150A113 Cluster: 3''''5''''-cyclic nucleotide pho... 119 4e-26
UniRef50_A7SGA1 Cluster: Predicted protein; n=1; Nematostella ve... 119 4e-26
UniRef50_Q4T098 Cluster: Chromosome undetermined SCAF11274, whol... 118 9e-26
UniRef50_Q23AZ3 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 118 9e-26
UniRef50_Q8SXR0 Cluster: RE69157p; n=9; Coelomata|Rep: RE69157p ... 116 3e-25
UniRef50_Q14123 Cluster: Calcium/calmodulin-dependent 3',5'-cycl... 116 3e-25
UniRef50_UPI0001555C30 Cluster: PREDICTED: hypothetical protein,... 113 2e-24
UniRef50_O18696 Cluster: Probable 3',5'-cyclic phosphodiesterase... 112 4e-24
UniRef50_Q4RH59 Cluster: Chromosome undetermined SCAF15069, whol... 111 8e-24
UniRef50_UPI0000D56A7E Cluster: PREDICTED: similar to High-affin... 110 2e-23
UniRef50_Q23RI8 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 110 2e-23
UniRef50_A0CZ03 Cluster: Chromosome undetermined scaffold_31, wh... 109 4e-23
UniRef50_Q01C40 Cluster: Cyclic GMP phosphodiesterase; n=1; Ostr... 108 7e-23
UniRef50_UPI00015B5210 Cluster: PREDICTED: similar to ENSANGP000... 108 9e-23
UniRef50_Q6S998 Cluster: CAMP-specific phosphodiesterase; n=3; L... 107 2e-22
UniRef50_O96075 Cluster: EFPDE1; n=1; Ephydatia fluviatilis|Rep:... 106 4e-22
UniRef50_O76083 Cluster: High affinity cGMP-specific 3',5'-cycli... 105 5e-22
UniRef50_A2DG30 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 104 1e-21
UniRef50_A2EIP4 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 104 2e-21
UniRef50_A7SVX8 Cluster: Predicted protein; n=1; Nematostella ve... 103 3e-21
UniRef50_A2DJF3 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 102 5e-21
UniRef50_O95263 Cluster: High affinity cAMP-specific and IBMX-in... 100 2e-20
UniRef50_UPI0000519BD4 Cluster: PREDICTED: similar to phosphodie... 100 2e-20
UniRef50_UPI0000E46CDB Cluster: PREDICTED: similar to phosphodie... 100 4e-20
UniRef50_Q8CFW8 Cluster: Phosphodiesterase 8B; n=13; Euteleostom... 100 4e-20
UniRef50_Q6S996 Cluster: Class I phosphodiesterase PDEB1; n=21; ... 100 4e-20
UniRef50_UPI0000E7FF0E Cluster: PREDICTED: similar to cAMP phosp... 99 6e-20
UniRef50_A2ENJ2 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 97 2e-19
UniRef50_Q388U6 Cluster: 3', 5'-cyclic nucleotide phosphodiester... 97 3e-19
UniRef50_Q13946 Cluster: High affinity cAMP-specific 3',5'-cycli... 97 3e-19
UniRef50_UPI00015B4893 Cluster: PREDICTED: similar to camp-speci... 96 4e-19
UniRef50_UPI0000DB6B8B Cluster: PREDICTED: similar to phosphodie... 96 4e-19
UniRef50_UPI0000D577EC Cluster: PREDICTED: similar to CG32648-PA... 96 4e-19
UniRef50_A0EBQ7 Cluster: Chromosome undetermined scaffold_88, wh... 96 4e-19
UniRef50_A0CB76 Cluster: Chromosome undetermined scaffold_163, w... 96 5e-19
UniRef50_Q16J23 Cluster: Camp-specific 3,5-cyclic phosphodiester... 94 2e-18
UniRef50_A2DF08 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 94 2e-18
UniRef50_A7SVS5 Cluster: Predicted protein; n=1; Nematostella ve... 93 4e-18
UniRef50_A0EGK4 Cluster: Chromosome undetermined scaffold_95, wh... 92 7e-18
UniRef50_A2D762 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 92 9e-18
UniRef50_Q6NNF2 Cluster: SD02170p; n=9; Diptera|Rep: SD02170p - ... 91 1e-17
UniRef50_A2EY05 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 91 1e-17
UniRef50_A0DF61 Cluster: Chromosome undetermined scaffold_49, wh... 91 2e-17
UniRef50_Q4SPD6 Cluster: Chromosome 16 SCAF14537, whole genome s... 90 4e-17
UniRef50_Q54HY3 Cluster: Putative uncharacterized protein Pde4; ... 89 5e-17
UniRef50_Q4D500 Cluster: Phosphodiesterase, putative; n=3; Trypa... 89 5e-17
UniRef50_A7RXZ4 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 89 8e-17
UniRef50_Q8I0P7 Cluster: Probable 3',5'-cyclic phosphodiesterase... 88 1e-16
UniRef50_A2FKH2 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 87 2e-16
UniRef50_A2FBN7 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 87 2e-16
UniRef50_A2DYU6 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 87 2e-16
UniRef50_Q23917 Cluster: 3',5'-cyclic-nucleotide phosphodiestera... 87 2e-16
UniRef50_Q7PQX7 Cluster: ENSANGP00000010843; n=6; Coelomata|Rep:... 85 1e-15
UniRef50_A2F408 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 85 1e-15
UniRef50_A2G2M9 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 84 2e-15
UniRef50_A2ERL4 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 84 2e-15
UniRef50_Q9N2V9 Cluster: Probable 3',5'-cyclic phosphodiesterase... 84 2e-15
UniRef50_A4RUJ3 Cluster: Predicted protein; n=1; Ostreococcus lu... 84 2e-15
UniRef50_Q16VA1 Cluster: High-affinity cgmp-specific 3,5-cyclic ... 84 2e-15
UniRef50_A4HHP3 Cluster: Putative uncharacterized protein; n=3; ... 84 2e-15
UniRef50_Q4SI77 Cluster: Chromosome 5 SCAF14581, whole genome sh... 83 3e-15
UniRef50_O96077 Cluster: EFPDE3; n=1; Ephydatia fluviatilis|Rep:... 83 3e-15
UniRef50_A2E8N2 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 83 3e-15
UniRef50_UPI0000660DD6 Cluster: Homolog of Homo sapiens "Phospho... 83 4e-15
UniRef50_UPI00015B464B Cluster: PREDICTED: similar to ENSANGP000... 83 5e-15
UniRef50_Q57V52 Cluster: 3', 5'-cyclic nucleotide phosphodiester... 83 5e-15
UniRef50_Q01CI7 Cluster: Cyclic GMP phosphodiesterase; n=1; Ostr... 82 7e-15
UniRef50_A3FQ29 Cluster: CGMP phosphodiesterase A4; n=2; Cryptos... 82 7e-15
UniRef50_A2FQ29 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 82 7e-15
UniRef50_Q4RSB8 Cluster: Chromosome 13 SCAF15000, whole genome s... 82 9e-15
UniRef50_A5JZK2 Cluster: 3',5'-cyclic-nucleotide phosphodiestera... 82 9e-15
UniRef50_Q13370 Cluster: cGMP-inhibited 3',5'-cyclic phosphodies... 82 9e-15
UniRef50_A7AR41 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 81 1e-14
UniRef50_A2DNV4 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 81 1e-14
UniRef50_A2EHB3 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 80 3e-14
UniRef50_A2F9J4 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 80 4e-14
UniRef50_A0EHP5 Cluster: Chromosome undetermined scaffold_97, wh... 80 4e-14
UniRef50_O00408 Cluster: cGMP-dependent 3',5'-cyclic phosphodies... 79 9e-14
UniRef50_Q9VYJ0 Cluster: CG32648-PA; n=3; Coelomata|Rep: CG32648... 78 1e-13
UniRef50_UPI00015B4531 Cluster: PREDICTED: similar to cyclic GMP... 76 5e-13
UniRef50_UPI0000E48F4D Cluster: PREDICTED: similar to camp and c... 76 5e-13
UniRef50_Q4SV96 Cluster: Chromosome 10 SCAF13771, whole genome s... 65 6e-13
UniRef50_Q8I6Y6 Cluster: CGMP-specific phosphodiesterase; n=3; D... 76 6e-13
UniRef50_Q5CXM2 Cluster: Membrane associated HD superfamily cycl... 76 6e-13
UniRef50_O96076 Cluster: EFPDE2; n=1; Ephydatia fluviatilis|Rep:... 76 6e-13
UniRef50_UPI000065CC62 Cluster: cGMP-inhibited 3',5'-cyclic phos... 64 8e-13
UniRef50_UPI000150A9A4 Cluster: 3''''5''''-cyclic nucleotide pho... 73 3e-12
UniRef50_Q14432 Cluster: cGMP-inhibited 3',5'-cyclic phosphodies... 73 3e-12
UniRef50_Q17L35 Cluster: Cgmp-dependent 3,5-cyclic phosphodieste... 73 4e-12
UniRef50_UPI00006CB6E9 Cluster: 3''''5''''-cyclic nucleotide pho... 72 8e-12
UniRef50_Q4RR95 Cluster: Chromosome 14 SCAF15003, whole genome s... 72 8e-12
UniRef50_A6R1R4 Cluster: Predicted protein; n=1; Ajellomyces cap... 72 8e-12
UniRef50_Q3SBD3 Cluster: Sperm phosphodiesterase 5; n=1; Strongy... 71 1e-11
UniRef50_Q6CHK1 Cluster: Similar to tr|Q8NJP9 Candida albicans H... 71 1e-11
UniRef50_Q1JT10 Cluster: Phosphodiesterase, putative; n=2; Eukar... 71 2e-11
UniRef50_A0BZW8 Cluster: Chromosome undetermined scaffold_14, wh... 71 2e-11
UniRef50_A0D3N1 Cluster: Chromosome undetermined scaffold_36, wh... 70 3e-11
UniRef50_Q5BYM4 Cluster: SJCHGC06481 protein; n=1; Schistosoma j... 70 4e-11
UniRef50_UPI00006CF33D Cluster: 3''''5''''-cyclic nucleotide pho... 68 1e-10
UniRef50_Q3KVL8 Cluster: High-affinity phosphodiesterase; n=4; E... 68 1e-10
UniRef50_A1D4A4 Cluster: High affinity cAMP phosphodiesterase, p... 68 1e-10
UniRef50_A4VDP2 Cluster: Cyclic nucleotide phosphodiesterase; n=... 68 2e-10
UniRef50_A2GFY4 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 67 3e-10
UniRef50_O76074 Cluster: cGMP-specific 3',5'-cyclic phosphodiest... 67 3e-10
UniRef50_Q29FT2 Cluster: GA17041-PA; n=1; Drosophila pseudoobscu... 66 4e-10
UniRef50_Q4KL87 Cluster: MGC116558 protein; n=2; Xenopus|Rep: MG... 66 5e-10
UniRef50_Q53I59 Cluster: Cyclic nucleotide specific phosphodiest... 66 7e-10
UniRef50_A7SW30 Cluster: Predicted protein; n=2; Nematostella ve... 65 9e-10
UniRef50_UPI000023CCA1 Cluster: hypothetical protein FG06914.1; ... 65 1e-09
UniRef50_Q4SVG8 Cluster: Chromosome undetermined SCAF13758, whol... 64 2e-09
UniRef50_A0CZB5 Cluster: Chromosome undetermined scaffold_32, wh... 64 2e-09
UniRef50_P30645 Cluster: Probable 3',5'-cyclic phosphodiesterase... 64 2e-09
UniRef50_Q9Y233 Cluster: cAMP and cAMP-inhibited cGMP 3',5'-cycl... 64 3e-09
UniRef50_UPI0000F1D4E2 Cluster: PREDICTED: similar to Phosphodie... 63 3e-09
UniRef50_A5K0J4 Cluster: 3',5'-cyclic-nucleotide phosphodiestera... 63 5e-09
UniRef50_A0DIM1 Cluster: Chromosome undetermined scaffold_52, wh... 63 5e-09
UniRef50_Q1DXU2 Cluster: Putative uncharacterized protein; n=1; ... 63 5e-09
UniRef50_Q4FXD4 Cluster: Putative uncharacterized protein; n=3; ... 62 6e-09
UniRef50_A0CG66 Cluster: Chromosome undetermined scaffold_179, w... 62 6e-09
UniRef50_P16499 Cluster: Rod cGMP-specific 3',5'-cyclic phosphod... 62 6e-09
UniRef50_Q7QRM3 Cluster: GLP_481_5888_1773; n=1; Giardia lamblia... 62 8e-09
UniRef50_Q7Q8G2 Cluster: ENSANGP00000013023; n=2; Diptera|Rep: E... 62 8e-09
UniRef50_A5JZK3 Cluster: 3',5'-cyclic-nucleotide phosphodiestera... 62 1e-08
UniRef50_A0BZK9 Cluster: Chromosome undetermined scaffold_139, w... 62 1e-08
UniRef50_Q9HCR9 Cluster: Dual 3',5'-cyclic-AMP and -GMP phosphod... 61 2e-08
UniRef50_A0E2C5 Cluster: Chromosome undetermined scaffold_74, wh... 60 3e-08
UniRef50_UPI0000588CD9 Cluster: PREDICTED: hypothetical protein;... 60 4e-08
UniRef50_Q4N6H0 Cluster: Putative uncharacterized protein; n=1; ... 60 4e-08
UniRef50_A2DM90 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 60 4e-08
UniRef50_A6S8A0 Cluster: Putative uncharacterized protein; n=2; ... 59 6e-08
UniRef50_A0D565 Cluster: Chromosome undetermined scaffold_38, wh... 59 7e-08
UniRef50_A0E1V7 Cluster: Chromosome undetermined scaffold_74, wh... 58 1e-07
UniRef50_Q16HU8 Cluster: Camp and camp-inhibited cgmp 3,5-cyclic... 58 1e-07
UniRef50_Q22CV4 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 58 2e-07
UniRef50_UPI0000D8B81A Cluster: UPI0000D8B81A related cluster; n... 57 2e-07
UniRef50_A7AS42 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 56 5e-07
UniRef50_Q7RXW7 Cluster: Putative uncharacterized protein NCU004... 55 9e-07
UniRef50_Q6BSL2 Cluster: Similar to tr|O94034 Candida albicans N... 55 1e-06
UniRef50_A0CU34 Cluster: Chromosome undetermined scaffold_28, wh... 54 2e-06
UniRef50_Q9VFI9 Cluster: CG8279-PA; n=8; Endopterygota|Rep: CG82... 54 2e-06
UniRef50_Q0V6F8 Cluster: Putative uncharacterized protein; n=1; ... 54 2e-06
UniRef50_O94034 Cluster: Nucleotide phosphodiesterase; n=4; Sacc... 54 2e-06
UniRef50_A2DCH1 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 53 4e-06
UniRef50_P91119 Cluster: Probable 3',5'-cyclic phosphodiesterase... 53 4e-06
UniRef50_Q9VJ79 Cluster: Dual 3',5'-cyclic-AMP and -GMP phosphod... 53 4e-06
UniRef50_Q2H9G5 Cluster: Putative uncharacterized protein; n=1; ... 52 7e-06
UniRef50_UPI0001554EBF Cluster: PREDICTED: similar to cyclic nuc... 51 2e-05
UniRef50_Q7YYN8 Cluster: Phosphdiesterase, possible; n=2; Crypto... 51 2e-05
UniRef50_A3FPW6 Cluster: Phosphdiesterase, putative; n=1; Crypto... 51 2e-05
UniRef50_A2G4P7 Cluster: GAF domain containing protein; n=1; Tri... 50 3e-05
UniRef50_UPI000065E700 Cluster: Cone cGMP-specific 3',5'-cyclic ... 50 3e-05
UniRef50_Q2V2M6 Cluster: CGMP-specific phosphodiesterase; n=3; P... 50 5e-05
UniRef50_Q22VA7 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 49 8e-05
UniRef50_UPI0000D555D7 Cluster: PREDICTED: similar to phosphodie... 48 1e-04
UniRef50_UPI00006CD10E Cluster: 3''''5''''-cyclic nucleotide pho... 48 1e-04
UniRef50_A2FQB0 Cluster: GAF domain containing protein; n=1; Tri... 48 2e-04
UniRef50_A0EF18 Cluster: Chromosome undetermined scaffold_92, wh... 48 2e-04
UniRef50_Q53S13 Cluster: Putative uncharacterized protein PDE11A... 48 2e-04
UniRef50_Q4N806 Cluster: 3',5' cyclic nucleotide phosphodiestera... 46 4e-04
UniRef50_A2FK96 Cluster: GAF domain containing protein; n=3; Tri... 46 7e-04
UniRef50_Q4RG61 Cluster: Chromosome 2 SCAF15106, whole genome sh... 45 0.001
UniRef50_A2E0V4 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 45 0.001
UniRef50_Q8IKD3 Cluster: Cyclic nucleotide phosphodiesterase, pu... 44 0.002
UniRef50_Q57ZK5 Cluster: 3', 5'-cyclic nucleotide phosphodiester... 42 0.007
UniRef50_A2E4B2 Cluster: Response regulator receiver domain cont... 42 0.007
UniRef50_A5K353 Cluster: 3',5'-cyclic-nucleotide phosphodiestera... 42 0.009
UniRef50_A2E5S0 Cluster: GAF domain containing protein; n=1; Tri... 42 0.009
UniRef50_Q5C1P7 Cluster: SJCHGC07646 protein; n=1; Schistosoma j... 41 0.021
UniRef50_A7T5L5 Cluster: Predicted protein; n=1; Nematostella ve... 41 0.021
UniRef50_Q4DUD4 Cluster: CAMP-specific phosphodiesterase, putati... 40 0.037
UniRef50_Q758Y3 Cluster: ADR395Cp; n=1; Eremothecium gossypii|Re... 38 0.20
UniRef50_A5DVX9 Cluster: Putative uncharacterized protein; n=1; ... 36 0.60
UniRef50_Q4DJ46 Cluster: Putative uncharacterized protein; n=2; ... 36 0.80
UniRef50_Q6FM93 Cluster: Similar to sp|P06776 Saccharomyces cere... 35 1.1
UniRef50_Q5K8K8 Cluster: Mitochondrion protein, putative; n=2; F... 35 1.4
UniRef50_A2FDY7 Cluster: Putative uncharacterized protein; n=1; ... 34 1.8
UniRef50_Q4RHZ1 Cluster: Chromosome 8 SCAF15044, whole genome sh... 34 2.4
UniRef50_A5N7K8 Cluster: Response regulator-related protein; n=2... 34 2.4
UniRef50_A0YKX3 Cluster: Sensor protein; n=1; Lyngbya sp. PCC 81... 34 2.4
UniRef50_A4C531 Cluster: Sensory box protein; n=1; Pseudoalterom... 33 3.2
UniRef50_Q9NHN7 Cluster: Septin interacting protein; n=12; Dipte... 33 3.2
UniRef50_Q5BVJ4 Cluster: SJCHGC04836 protein; n=1; Schistosoma j... 33 3.2
UniRef50_A2E1P4 Cluster: Beige/BEACH domain containing protein; ... 33 4.3
UniRef50_Q6R988 Cluster: Putative uncharacterized protein orf186... 33 5.6
UniRef50_A5BXR8 Cluster: Putative uncharacterized protein; n=1; ... 33 5.6
UniRef50_Q0E4Y6 Cluster: 16 kDa; n=1; Spodoptera frugiperda asco... 32 7.4
UniRef50_A7MG03 Cluster: Putative uncharacterized protein; n=1; ... 32 7.4
UniRef50_A1GCI9 Cluster: Peptidase U61, LD-carboxypeptidase A; n... 32 7.4
UniRef50_A4RPY9 Cluster: Putative uncharacterized protein; n=1; ... 32 7.4
UniRef50_UPI00006CFB29 Cluster: hypothetical protein TTHERM_0047... 32 9.8
UniRef50_A6TT22 Cluster: GerA spore germination protein; n=1; Al... 32 9.8
UniRef50_Q7R1F8 Cluster: GLP_38_64512_71054; n=1; Giardia lambli... 32 9.8
UniRef50_Q4D8H9 Cluster: Hydrolase, alpha/beta fold family, puta... 32 9.8
UniRef50_Q6CY30 Cluster: Similar to sp|P06776 Saccharomyces cere... 32 9.8
UniRef50_Q58073 Cluster: Uncharacterized protein MJ0659; n=1; Me... 32 9.8
UniRef50_P06776 Cluster: 3',5'-cyclic-nucleotide phosphodiestera... 32 9.8
>UniRef50_Q9W4T4 Cluster: cAMP-specific 3',5'-cyclic
phosphodiesterase, isoform I; n=38; Coelomata|Rep:
cAMP-specific 3',5'-cyclic phosphodiesterase, isoform I -
Drosophila melanogaster (Fruit fly)
Length = 1209
Score = 351 bits (862), Expect = 8e-96
Identities = 165/176 (93%), Positives = 171/176 (97%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAFKLLQN GCDIF N+ +++QRQTLRKMVID+VLSTDMSKHMSLLADLKTMVETKKVAG
Sbjct: 947 VAFKLLQNQGCDIFCNM-QKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAG 1005
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFF QGD+ERE GMDI
Sbjct: 1006 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDI 1065
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI
Sbjct: 1066 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 1121
>UniRef50_Q13945 Cluster: 3',5'-cyclic AMP phosphodiesterase; n=37;
Coelomata|Rep: 3',5'-cyclic AMP phosphodiesterase - Homo
sapiens (Human)
Length = 606
Score = 309 bits (759), Expect = 2e-83
Identities = 143/176 (81%), Positives = 160/176 (90%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF+NL ++QRQTLRKMVIDMVL+TDMSKHMSLLADLKTMVETKKV
Sbjct: 352 VGFKLLQEEHCDIFMNL-TKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTS 410
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W +MEEFFQQGD+ERE GM+I
Sbjct: 411 SGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEI 470
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLV PDAQDILDTLE+NR++YQSMI
Sbjct: 471 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMI 526
>UniRef50_P27815 Cluster: cAMP-specific 3',5'-cyclic phosphodiesterase
4A; n=160; Eumetazoa|Rep: cAMP-specific 3',5'-cyclic
phosphodiesterase 4A - Homo sapiens (Human)
Length = 886
Score = 307 bits (753), Expect = 1e-82
Identities = 141/176 (80%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ D CDIF NL + QRQ+LRKMVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 509 VGFKLLQEDNCDIFQNL-SKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTS 567
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W +M EFFQQGDRERE GM+I
Sbjct: 568 SGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEI 627
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLVHPDAQ+ILDTLE+NRD+Y S I
Sbjct: 628 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI 683
>UniRef50_O43851 Cluster: PDE4C-delta109; n=18; Bilateria|Rep:
PDE4C-delta109 - Homo sapiens (Human)
Length = 427
Score = 302 bits (742), Expect = 3e-81
Identities = 138/176 (78%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL +QR +LR+MVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 179 VGFKLLQAENCDIFQNL-SAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTS 237
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W +M EFFQQGDRERE G+DI
Sbjct: 238 LGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDI 297
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYI HPLWETWADLVHPDAQD+LDTLE+NR++YQS I
Sbjct: 298 SPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKI 353
>UniRef50_UPI000065D378 Cluster: cAMP-specific 3',5'-cyclic
phosphodiesterase 4A (EC 3.1.4.17) (DPDE2) (PDE46).;
n=4; Euteleostomi|Rep: cAMP-specific 3',5'-cyclic
phosphodiesterase 4A (EC 3.1.4.17) (DPDE2) (PDE46). -
Takifugu rubripes
Length = 715
Score = 263 bits (645), Expect(2) = 1e-76
Identities = 117/143 (81%), Positives = 132/143 (92%)
Frame = +2
Query: 116 VLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLP 295
VL+TDMSKHMSLLADLKTMVETKKV SGVLLLD+YTDRIQVL NLVHCADLSNPTKPL
Sbjct: 538 VLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDHYTDRIQVLRNLVHCADLSNPTKPLA 597
Query: 296 LYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADL 475
+Y++W +MEEFF+QGD+ERE GM+ISPMCD+H A++EKSQVGFIDYIVHPLWETW DL
Sbjct: 598 VYRQWTERIMEEFFRQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWGDL 657
Query: 476 VHPDAQDILDTLEENRDYYQSMI 544
VHPDAQ+ILDTLE+NRD+YQS I
Sbjct: 658 VHPDAQEILDTLEDNRDWYQSTI 680
Score = 45.6 bits (103), Expect(2) = 1e-76
Identities = 22/33 (66%), Positives = 25/33 (75%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDM 115
V FKLL D CDIF NL + QRQ+LRK+VIDM
Sbjct: 478 VGFKLLHEDNCDIFQNL-SKRQRQSLRKLVIDM 509
>UniRef50_Q4SP32 Cluster: Chromosome 15 SCAF14542, whole genome
shotgun sequence; n=4; Tetraodontidae|Rep: Chromosome 15
SCAF14542, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 763
Score = 285 bits (700), Expect = 3e-76
Identities = 141/202 (69%), Positives = 160/202 (79%), Gaps = 26/202 (12%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMV-------------------------- 118
V FKLLQ D CDIF NL ++QRQTLR+MVIDMV
Sbjct: 519 VGFKLLQEDNCDIFQNL-TKKQRQTLRRMVIDMVRAARARAQGSRARFPSATLRWSPHQV 577
Query: 119 LSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPL 298
L+TDMSKHMSLLADLKTMVETKKV SGVLLLDNYTDR+QVL N+VHCADLSNPTKPL L
Sbjct: 578 LATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRMQVLRNMVHCADLSNPTKPLDL 637
Query: 299 YKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLV 478
Y++W +M+EFF QGDRERE GM+ISPMCD+H A++E++QVGFIDYIVHPLWETWADLV
Sbjct: 638 YRQWTDRIMDEFFHQGDRERERGMEISPMCDKHTASVERTQVGFIDYIVHPLWETWADLV 697
Query: 479 HPDAQDILDTLEENRDYYQSMI 544
HPDAQDILDTLE+NR++YQSMI
Sbjct: 698 HPDAQDILDTLEDNRNWYQSMI 719
>UniRef50_Q22000 Cluster: Probable 3',5'-cyclic phosphodiesterase
pde-4; n=7; Caenorhabditis elegans|Rep: Probable
3',5'-cyclic phosphodiesterase pde-4 - Caenorhabditis
elegans
Length = 674
Score = 268 bits (657), Expect = 6e-71
Identities = 123/176 (69%), Positives = 151/176 (85%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAFKLLQ+ CD NL +QR RK+VIDMVL+TDMSKHMSLLADLKTMVE KKVAG
Sbjct: 483 VAFKLLQDSNCDFLANL-SRKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAG 541
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ V++LD Y D+IQVL++++H ADLSNPTKP+ LY++W +MEE+++QGD+E+E G++I
Sbjct: 542 NNVIVLDKYNDKIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEKELGLEI 601
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCDR N TIEKSQVGFIDYIVHPL+ETWADLV+PDAQ+ILD LEENR++YQS I
Sbjct: 602 SPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPDAQNILDQLEENREWYQSRI 657
>UniRef50_Q3UEI1-2 Cluster: Isoform 2 of Q3UEI1 ; n=1; Mus
musculus|Rep: Isoform 2 of Q3UEI1 - Mus musculus (Mouse)
Length = 652
Score = 131 bits (317), Expect(2) = 3e-57
Identities = 55/69 (79%), Positives = 64/69 (92%)
Frame = +2
Query: 338 QQGDREREHGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEE 517
QQGDRERE G+DISPMCD+H A++EKSQVGFIDYI PLWETWADLVHPDAQ++LDTLE+
Sbjct: 537 QQGDRERESGLDISPMCDKHTASMEKSQVGFIDYIAQPLWETWADLVHPDAQELLDTLED 596
Query: 518 NRDYYQSMI 544
NR++YQS I
Sbjct: 597 NREWYQSRI 605
Score = 113 bits (271), Expect(2) = 3e-57
Identities = 57/74 (77%), Positives = 63/74 (85%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL +QR +LR+MVIDMVL+TDMSKHMSLLADLKTMVETKKV
Sbjct: 465 VGFKLLQGENCDIFRNL-STKQRLSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVTS 523
Query: 197 SGVLLLDNYTDRIQ 238
GVLLLDNY+DRIQ
Sbjct: 524 LGVLLLDNYSDRIQ 537
>UniRef50_O96078 Cluster: EFPDE4; n=1; Ephydatia fluviatilis|Rep:
EFPDE4 - Ephydatia fluviatilis
Length = 698
Score = 194 bits (472), Expect = 1e-48
Identities = 89/173 (51%), Positives = 130/173 (75%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
+AF+L+++ C+ F+ + Q+Q RK++IDMVL+TDMS+H L LKT++E+ KVA
Sbjct: 491 LAFELMKDPTCN-FLESTCKSQKQAFRKLIIDMVLATDMSRHFKYLGQLKTLLESNKVAN 549
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+G+L LD Y DR++VL+ L+HCADLSN TK + +W +MEE ++QGD ER+ G+ +
Sbjct: 550 NGLLQLDKYHDRVEVLQGLLHCADLSNQTKSFHIASQWSQRIMEESYRQGDEERKLGIPV 609
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQ 535
+P+ DR + +IEK QV FIDYIV+PLWETWA+LV+PDAQDI+ +L + RD +Q
Sbjct: 610 NPLGDR-SVSIEKCQVTFIDYIVYPLWETWAELVYPDAQDIVCSLMDTRDQWQ 661
>UniRef50_Q005X2 Cluster: Phosphodiesterase 1; n=1;
Strongylocentrotus purpuratus|Rep: Phosphodiesterase 1 -
Strongylocentrotus purpuratus (Purple sea urchin)
Length = 680
Score = 130 bits (313), Expect = 3e-29
Identities = 63/153 (41%), Positives = 99/153 (64%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
+F+L+++D +I NL +EE + LR +VIDMVL+TDMS H + +K+M+ T +
Sbjct: 363 SFRLMRDDERNILANLSKEEYTE-LRNLVIDMVLATDMSFHFQQIKQMKSMISTTEAL-- 419
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS 379
D+ +V+ +HCAD+S+P+K + +W LL+ EFF+QGDRERE G+ IS
Sbjct: 420 ---------DKPKVMALTLHCADISHPSKEWKFHYKWTTLLIREFFRQGDREREMGLPIS 470
Query: 380 PMCDRHNATIEKSQVGFIDYIVHPLWETWADLV 478
P+CDR++ + +SQ+GFID+IV P D++
Sbjct: 471 PLCDRNSTLLAESQIGFIDFIVDPSMNICGDMI 503
>UniRef50_UPI0000DB7125 Cluster: PREDICTED: similar to
Phosphodiesterase 1c CG14940-PA; n=1; Apis
mellifera|Rep: PREDICTED: similar to Phosphodiesterase
1c CG14940-PA - Apis mellifera
Length = 731
Score = 125 bits (302), Expect = 6e-28
Identities = 59/153 (38%), Positives = 97/153 (63%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
+F++++ D C+I NL EE R+ R +VIDMVL+TDMS H L ++K ++
Sbjct: 518 SFRIMREDECNILQNLSREEFRE-FRSLVIDMVLATDMSFHFQQLKNMKNILS------- 569
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS 379
L + D+ + + ++HC D+S+P K L+ RW L+EEFF+QGD+E+ G+ S
Sbjct: 570 ---LAEPSVDKSKAVSLVLHCCDISHPAKRWDLHHRWTMQLLEEFFRQGDKEKALGLPFS 626
Query: 380 PMCDRHNATIEKSQVGFIDYIVHPLWETWADLV 478
P+CDR+N + +SQ+GFI++IV P + +D++
Sbjct: 627 PLCDRNNTLVAESQIGFIEFIVEPSMQVCSDML 659
>UniRef50_UPI00006CBCA5 Cluster: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein; n=1; Tetrahymena
thermophila SB210|Rep: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein - Tetrahymena
thermophila SB210
Length = 649
Score = 123 bits (296), Expect = 3e-27
Identities = 60/174 (34%), Positives = 103/174 (59%)
Frame = +2
Query: 23 FKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSG 202
F+L + DI N +E+ R + R+MVI ++LSTDM+KH S +A LK+ + T G
Sbjct: 463 FQLFNDQNLDITANFTKEQYR-SFREMVISIILSTDMAKHFSDIAKLKSRLGTDDYDIKG 521
Query: 203 VLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISP 382
D+ ++ ++H D+SNP K +Y++W ++ EF+ QGD+ER G+ I+
Sbjct: 522 -------KDKQMCIDTIIHACDVSNPVKTWNVYQQWAHRVLSEFWSQGDQERSQGIQITY 574
Query: 383 MCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
+CDR+ KSQVGFID+IV PL+E + + P+ ++ + ++ N+ + ++
Sbjct: 575 LCDRYTTNTAKSQVGFIDFIVKPLYEVICNFL-PELKNYMQQIDSNKQKWNELV 627
>UniRef50_A4RV03 Cluster: Predicted protein; n=1; Ostreococcus
lucimarinus CCE9901|Rep: Predicted protein -
Ostreococcus lucimarinus CCE9901
Length = 401
Score = 122 bits (294), Expect = 5e-27
Identities = 66/174 (37%), Positives = 98/174 (56%), Gaps = 3/174 (1%)
Frame = +2
Query: 23 FKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG-- 196
F L QN+ ++ +E + +R+ +I VL TDM+ H L++ L +V K
Sbjct: 149 FSLCQNNEDANILSAFDESTYKEIRRSIISCVLHTDMAHHFKLVSRLNELVALGKKNNII 208
Query: 197 SGVLLLDNYTDRIQVLEN-LVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMD 373
+G + D Q++ N L+HCAD+SN KP L +W + ++EEFF QGDRER GM
Sbjct: 209 NGSPMKSTTDDERQLMLNVLLHCADISNAVKPNELCVKWASRVLEEFFNQGDRERSRGMS 268
Query: 374 ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQ 535
ISPM DR ++ SQ+ FI++++ PL+ + V P +L L ENR YYQ
Sbjct: 269 ISPMMDRETTSVGLSQINFIEFVIAPLYVQFV-AVFPALNGLLTRLIENRRYYQ 321
>UniRef50_UPI000150A113 Cluster: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein; n=1; Tetrahymena
thermophila SB210|Rep: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein - Tetrahymena
thermophila SB210
Length = 569
Score = 119 bits (287), Expect = 4e-26
Identities = 63/175 (36%), Positives = 102/175 (58%), Gaps = 1/175 (0%)
Frame = +2
Query: 17 VAFKLLQ-NDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVA 193
V FKLL+ N +IF + +++ + +R+ +I M+L TDM++H + LA LK + + +
Sbjct: 344 VTFKLLRDNPSINIFEGI-DKKTYKNVRETLIQMILKTDMNQHFTSLAQLKGRLASNEFD 402
Query: 194 GSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMD 373
D+ L L+H AD+SNP KP +Y+ W ++ EF+ QGD ER G+
Sbjct: 403 AKAA-------DKPLCLNTLLHAADVSNPFKPFHIYQEWTHRVLNEFWIQGDVERSRGLP 455
Query: 374 ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQS 538
IS +CDR+ I KSQ+GFID+IV P +ET + P+ + + E+N+ +Q+
Sbjct: 456 ISYLCDRYTTNIAKSQIGFIDFIVQPYFETICQFI-PELLNYMPLFEQNKQEWQT 509
>UniRef50_A7SGA1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 358
Score = 119 bits (287), Expect = 4e-26
Identities = 64/153 (41%), Positives = 97/153 (63%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
AF++LQ+D +I L+ E Q +R ++ID VL+TDMS H L +K + VAGS
Sbjct: 217 AFRILQDDEKNILSGLNLE-QYADVRSLMIDTVLATDMSSHFEQLRLMKVAL----VAGS 271
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS 379
+ + +V++ L+H AD+SNPTK ++++W +MEEFF QGD E E G+D+S
Sbjct: 272 PI-------ENREVVQLLLHVADISNPTKDWTIHRQWTTKIMEEFFTQGDMEIELGLDVS 324
Query: 380 PMCDRHNATIEKSQVGFIDYIVHPLWETWADLV 478
P+CDR I +SQ+GFID+IV P E ++++
Sbjct: 325 PLCDRSTTLIPESQIGFIDFIVSPALEVCSEVL 357
>UniRef50_Q4T098 Cluster: Chromosome undetermined SCAF11274, whole
genome shotgun sequence; n=4; Tetraodontidae|Rep:
Chromosome undetermined SCAF11274, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 601
Score = 118 bits (284), Expect = 9e-26
Identities = 62/162 (38%), Positives = 98/162 (60%), Gaps = 1/162 (0%)
Frame = +2
Query: 23 FKLLQ-NDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
++LLQ ND +I NL +++ R+ LR +V++MVL+TDMS H + +K
Sbjct: 314 YRLLQTNDDTNILSNLSKDDWRE-LRALVVEMVLATDMSCHFEQIKVMK----------- 361
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS 379
G+L D+ + L L+H AD+S+P KP L+ RW L+EEFF+QGD+E E G+ S
Sbjct: 362 GLLQQPEAIDKAKALSLLLHTADISHPAKPWSLHHRWTFSLLEEFFRQGDKEVELGLPFS 421
Query: 380 PMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILD 505
P+CDR + + +SQ+GFID+IV P + +++ +L+
Sbjct: 422 PLCDRKSTMVAQSQIGFIDFIVEPTFTVMTEMIEKIMTPLLE 463
>UniRef50_Q23AZ3 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein
- Tetrahymena thermophila SB210
Length = 577
Score = 118 bits (284), Expect = 9e-26
Identities = 58/172 (33%), Positives = 103/172 (59%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+L+N +IF N +E +Q R+MV++MVL+TDM+KH + ++ LK+ + G
Sbjct: 394 ILKNHNLNIFSNFSNDEYKQ-FREMVVNMVLATDMTKHFADISKLKSRIAATDFEIDG-- 450
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMC 388
D+ V+E+L+H +D+SNP +P + +W +M EF+ QGD E+ G+ ++ +C
Sbjct: 451 -----KDKKTVMESLLHASDISNPARPWEICYQWTNKVMTEFWAQGDEEKRLGLPVTYLC 505
Query: 389 DRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
DR KSQ GFID++V PL+E ++ + P+ Q + E+N++ + ++
Sbjct: 506 DRVETNTSKSQQGFIDFVVKPLFEIISNFL-PELQQFMINFEQNKEKWAELL 556
>UniRef50_Q8SXR0 Cluster: RE69157p; n=9; Coelomata|Rep: RE69157p -
Drosophila melanogaster (Fruit fly)
Length = 834
Score = 116 bits (280), Expect = 3e-25
Identities = 58/153 (37%), Positives = 95/153 (62%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
+F+LL+ D +I +L EE R+ LR +VI+MVL TDM+ H + ++ ++ ++
Sbjct: 546 SFRLLREDEYNILSHLSREEFRE-LRGLVIEMVLGTDMTNHFQQMKAMRQLLTLQEAT-- 602
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS 379
D+ +VL ++HC D+S+P K ++ RW LL+EEFF+QGD E+E G+ S
Sbjct: 603 --------IDKQKVLSLVLHCCDISHPAKQWGVHHRWTMLLLEEFFRQGDLEKELGLPFS 654
Query: 380 PMCDRHNATIEKSQVGFIDYIVHPLWETWADLV 478
P+CDR+N + +SQ+ FID+IV P +D++
Sbjct: 655 PLCDRNNTLVAESQICFIDFIVEPSMGVMSDML 687
>UniRef50_Q14123 Cluster: Calcium/calmodulin-dependent 3',5'-cyclic
nucleotide phosphodiesterase 1C; n=128;
Euteleostomi|Rep: Calcium/calmodulin-dependent
3',5'-cyclic nucleotide phosphodiesterase 1C - Homo
sapiens (Human)
Length = 709
Score = 116 bits (280), Expect = 3e-25
Identities = 60/163 (36%), Positives = 98/163 (60%), Gaps = 1/163 (0%)
Frame = +2
Query: 20 AFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
A++LLQ+D +I +NL +++ R+ R +VI+MV++TDMS H + +KT ++ +
Sbjct: 305 AYRLLQDDEEMNILINLSKDDWRE-FRTLVIEMVMATDMSCHFQQIKAMKTALQQPEAI- 362
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
++ + L ++H AD+S+P K L+ RW L+EEFF+QGDRE E G+
Sbjct: 363 ----------EKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPF 412
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILD 505
SP+CDR + + +SQVGFID+IV P + D+ ++D
Sbjct: 413 SPLCDRKSTMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLID 455
>UniRef50_UPI0001555C30 Cluster: PREDICTED: hypothetical protein,
partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
hypothetical protein, partial - Ornithorhynchus anatinus
Length = 319
Score = 113 bits (273), Expect = 2e-24
Identities = 56/138 (40%), Positives = 83/138 (60%)
Frame = +2
Query: 92 LRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADL 271
LR +VI+MVLSTDMS H + +KT ++ + D+ + L L+H AD+
Sbjct: 79 LRSLVIEMVLSTDMSCHFQQVKSMKTSLQQLE-----------RIDKSKALSLLLHAADI 127
Query: 272 SNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATIEKSQVGFIDYIVHP 451
S+PTK ++ RW LMEEFF+QGD+E E G+ SP+CDR + + +SQ+GFID+IV P
Sbjct: 128 SHPTKQWSVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQSQIGFIDFIVEP 187
Query: 452 LWETWADLVHPDAQDILD 505
+ D+ Q ++D
Sbjct: 188 TFSVLTDVADKSVQPLVD 205
>UniRef50_O18696 Cluster: Probable 3',5'-cyclic phosphodiesterase
pde-1; n=2; Caenorhabditis|Rep: Probable 3',5'-cyclic
phosphodiesterase pde-1 - Caenorhabditis elegans
Length = 664
Score = 112 bits (270), Expect = 4e-24
Identities = 59/152 (38%), Positives = 90/152 (59%)
Frame = +2
Query: 23 FKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSG 202
F+L++ D +I +L +E ++ LR MVI++VL+TDMS H + +K+M
Sbjct: 411 FRLMKEDDKNILTHLTRDEYKE-LRNMVIEIVLATDMSTHFMQIKTMKSM---------- 459
Query: 203 VLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISP 382
L L D+ + L +VH D+S+P KP L++RW ++EEFF+QGD E G+ SP
Sbjct: 460 -LSLPEGIDKNKALCLIVHACDISHPAKPWNLHERWTEGVLEEFFRQGDLEASMGLPYSP 518
Query: 383 MCDRHNATIEKSQVGFIDYIVHPLWETWADLV 478
+CDRH + SQ+GFID+IV P +L+
Sbjct: 519 LCDRHTVHVADSQIGFIDFIVEPTMVVCGELL 550
>UniRef50_Q4RH59 Cluster: Chromosome undetermined SCAF15069, whole
genome shotgun sequence; n=3; Euteleostomi|Rep:
Chromosome undetermined SCAF15069, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 695
Score = 111 bits (268), Expect = 8e-24
Identities = 59/163 (36%), Positives = 99/163 (60%), Gaps = 1/163 (0%)
Frame = +2
Query: 20 AFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
A++LLQ+D +I NL +++ R+ LR +V++MVL+TDMS H + +K ++ +
Sbjct: 384 AYRLLQDDDEMNILYNLSKDDWRE-LRALVVEMVLATDMSCHFQQVKAMKNFLQQPE--- 439
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
G+ D+ + L L+H AD+S+P K L+ W L+EEFF+QGD+E + G+
Sbjct: 440 -GI-------DKPKALSLLLHTADISHPAKNWDLHHHWTTSLLEEFFRQGDKEADLGLPF 491
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILD 505
SP+CDR + + +SQ+GFID+IV P + D++ ++D
Sbjct: 492 SPLCDRKSTMVAQSQIGFIDFIVVPTFTVLTDMMERIVTPLID 534
>UniRef50_UPI0000D56A7E Cluster: PREDICTED: similar to High-affinity
cAMP-specific and IBMX-insensitive 3,5-cyclic
phosphodiesterase 8A; n=1; Tribolium castaneum|Rep:
PREDICTED: similar to High-affinity cAMP-specific and
IBMX-insensitive 3,5-cyclic phosphodiesterase 8A -
Tribolium castaneum
Length = 862
Score = 110 bits (264), Expect = 2e-23
Identities = 64/175 (36%), Positives = 101/175 (57%), Gaps = 9/175 (5%)
Frame = +2
Query: 23 FKL-LQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
FKL L ++ ++F NL + E + R VIDM+L+T+M+KH LA + TK + S
Sbjct: 657 FKLTLGDERVNVFKNL-DRETYKIARHNVIDMILATEMTKHFEHLAKFVNVFCTK-TSNS 714
Query: 200 GVLLLDNYTDRIQVLENL-------VHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRER 358
+ L D + EN+ + C+D+SNPT+PL L W + EE+FQQ D E+
Sbjct: 715 DIELGDQDFPLLTQPENITLIKRMMIKCSDVSNPTRPLRLCVEWARRIAEEYFQQTDEEK 774
Query: 359 EHGMD-ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEEN 520
E G+ + PM DR+ +I KSQ+GF+DYI++ ++E W + D D++ + +N
Sbjct: 775 ERGLPVVMPMFDRNTCSIPKSQIGFVDYIINDMFEAWNAFI--DMPDLITYMRQN 827
>UniRef50_Q23RI8 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Tetrahymena thermophila SB210
Length = 807
Score = 110 bits (264), Expect = 2e-23
Identities = 56/147 (38%), Positives = 92/147 (62%)
Frame = +2
Query: 23 FKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSG 202
F L+Q + C+IFV+L ++E +++ R+ +I M+L TD S+H + LA LK + ++
Sbjct: 623 FLLMQEENCNIFVHLTKDEFKKS-RERIISMILHTDNSQHFADLAKLKGRLTSQDFDPKD 681
Query: 203 VLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISP 382
D+ + +L+H AD+SNP KP + ++W +++EF+ QGD ER+ G+ I+
Sbjct: 682 -------KDKDICMMSLLHSADVSNPYKPWEICRQWTFKVLDEFWNQGDLERQSGLPITY 734
Query: 383 MCDRHNATIEKSQVGFIDYIVHPLWET 463
+CDR KSQ GFID+IV PL+E+
Sbjct: 735 LCDRFTTNTSKSQAGFIDFIVKPLYES 761
>UniRef50_A0CZ03 Cluster: Chromosome undetermined scaffold_31, whole
genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_31,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 692
Score = 109 bits (262), Expect = 4e-23
Identities = 58/169 (34%), Positives = 101/169 (59%)
Frame = +2
Query: 38 NDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLD 217
N +IF +L ++ R+ +R+ +I MVLSTDM+ H S LA + V G
Sbjct: 520 NQKANIFESLTFQKYRR-IRESIISMVLSTDMAHHASELAITNSRVAAPDFEPYG----- 573
Query: 218 NYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRH 397
D+ ++++ +VH +D+SNPTK +YK+W ++ EF+ QGD+ERE G+ IS +C+R+
Sbjct: 574 --KDKQRLMDLVVHSSDVSNPTKSFEIYKQWTERVLTEFWLQGDKERELGLPISYLCNRY 631
Query: 398 NATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
+ ++Q+GFIDY+V P + + P + L+ L++N+ +Q ++
Sbjct: 632 TTNMAEAQLGFIDYVVKPTFSCVQGFL-PAFEPYLENLDKNKAKWQELV 679
>UniRef50_Q01C40 Cluster: Cyclic GMP phosphodiesterase; n=1;
Ostreococcus tauri|Rep: Cyclic GMP phosphodiesterase -
Ostreococcus tauri
Length = 674
Score = 108 bits (260), Expect = 7e-23
Identities = 68/197 (34%), Positives = 103/197 (52%), Gaps = 26/197 (13%)
Frame = +2
Query: 23 FKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVET------- 181
F L QN+ ++ +E+ +R+ +I VL TDM+ H L++ + MV
Sbjct: 389 FTLCQNNEDANILSAFDEDTYSVVRRTIIGCVLHTDMAHHFKLVSRMNEMVSLGRKTEII 448
Query: 182 KKVAGSGV-------LLLDNYTD------------RIQVLENLVHCADLSNPTKPLPLYK 304
+ GS + ++LD D R +L L+HCAD+SN KP L
Sbjct: 449 RSPIGSPMSSPIKSCVVLDREGDPSVAVSFKTDEERQLMLNVLLHCADISNAVKPNELCV 508
Query: 305 RWVALLMEEFFQQGDREREHGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHP 484
+W + ++EEFF QGDRER GM +SPM DR ++ SQ+ FI++++ PL+ +A + P
Sbjct: 509 KWASRVLEEFFNQGDRERAKGMSVSPMMDRETTSVGLSQINFIEFVIAPLYVQFA-AIFP 567
Query: 485 DAQDILDTLEENRDYYQ 535
+LD L ENR YYQ
Sbjct: 568 AVSHLLDRLIENRRYYQ 584
>UniRef50_UPI00015B5210 Cluster: PREDICTED: similar to
ENSANGP00000018818; n=2; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000018818 - Nasonia
vitripennis
Length = 849
Score = 108 bits (259), Expect = 9e-23
Identities = 60/170 (35%), Positives = 100/170 (58%), Gaps = 2/170 (1%)
Frame = +2
Query: 17 VAFKL-LQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVA 193
+ FK+ L +D +IF NLH + + ++R+ +IDM+L+T+M+KH LA + +T
Sbjct: 655 LTFKVTLSDDNVNIFKNLHADVYK-SMRQNIIDMILATEMTKHFEHLARFVNLFDT---- 709
Query: 194 GSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMD 373
S LL +N T +++ + CAD+SNPT+P LY W + EE+F Q D E++ +
Sbjct: 710 -SAFLLPENVTLTKRMM---IKCADVSNPTRPFRLYVEWTRRIAEEYFDQTDEEKKKKLP 765
Query: 374 -ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEEN 520
+ PM DR I KSQ+GF++YI++ + E W + D +++ + EN
Sbjct: 766 VVMPMFDRACCCIPKSQIGFVEYIINDMMEAWDAFI--DMPEMVGYMSEN 813
>UniRef50_Q6S998 Cluster: CAMP-specific phosphodiesterase; n=3;
Leishmania|Rep: CAMP-specific phosphodiesterase -
Leishmania major
Length = 631
Score = 107 bits (257), Expect = 2e-22
Identities = 59/170 (34%), Positives = 98/170 (57%)
Frame = +2
Query: 23 FKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSG 202
F+L++N +I + +EQ +R+ +I+MVL+TDM H +A LK ++
Sbjct: 465 FELMKNPAFNILASF-SDEQHHEVRETMIEMVLATDMGSHGKYVASLKGKMQEHSS---- 519
Query: 203 VLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISP 382
++ L + AD+SN +PL +Y RW A + +EF+QQGDRER G++ SP
Sbjct: 520 ---FTQTAEQNLCLAIALKMADISNCGRPLDIYLRWGAKVSDEFYQQGDRERNLGLECSP 576
Query: 383 MCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYY 532
DR ++ KSQ+ F++YI+ P +E A+L+ PD + + +EEN+ Y+
Sbjct: 577 FMDRLQPSLAKSQIAFMNYIITPFFEQVAELL-PDMRFAVALVEENKAYW 625
>UniRef50_O96075 Cluster: EFPDE1; n=1; Ephydatia fluviatilis|Rep:
EFPDE1 - Ephydatia fluviatilis
Length = 628
Score = 106 bits (254), Expect = 4e-22
Identities = 57/153 (37%), Positives = 94/153 (61%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
AF LL+ D +I NL E+ R +R +V++MVL+TDMS H L ++ ++ + V
Sbjct: 356 AFTLLKEDELNILKNLKLEDFR-LVRSLVVEMVLATDMSSHSDQLKHMRQLISSPDV--- 411
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS 379
++ R +VL L+H AD+S+P K ++ + + L+EEFF+QGD+E + G S
Sbjct: 412 ---IVQIEKGRSKVLCLLLHMADISHPGKEWETHQEFSSRLVEEFFRQGDQEMQLGRTCS 468
Query: 380 PMCDRHNATIEKSQVGFIDYIVHPLWETWADLV 478
P+C+R+ ++ + Q+GFIDYIV P ++ DL+
Sbjct: 469 PLCNRNTTSVPECQLGFIDYIVSPSFDVCGDLL 501
>UniRef50_O76083 Cluster: High affinity cGMP-specific 3',5'-cyclic
phosphodiesterase 9A; n=62; Eumetazoa|Rep: High affinity
cGMP-specific 3',5'-cyclic phosphodiesterase 9A - Homo
sapiens (Human)
Length = 593
Score = 105 bits (253), Expect = 5e-22
Identities = 54/175 (30%), Positives = 101/175 (57%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAF++L C+IF N+ + +Q +R+ +I ++L+TDM++H ++ K +E +
Sbjct: 388 VAFQILAEPECNIFSNIPPDGFKQ-IRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 446
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ L ++++ L+ C D+SN +P+ + + WV L+EE+F Q DRE+ G+ +
Sbjct: 447 EEHMTL------LKMI--LIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPV 498
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+P DR T +Q+GFI +++ P++ET L + +L L E+RD Y+ +
Sbjct: 499 APFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 553
>UniRef50_A2DG30 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1090
Score = 104 bits (250), Expect = 1e-21
Identities = 57/175 (32%), Positives = 102/175 (58%), Gaps = 1/175 (0%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V ++ ND C++F L ++ +Q +VI+++L+TDM+KH ++L + T+++ K +
Sbjct: 855 VTIDIMSNDQCNLFSALPPQQFKQVWN-LVINLILATDMAKHFTILQEFNTLIDGKTFS- 912
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
++N R +L+ ++ DLSN ++P L RW A+L EEFF+QGD E GM
Sbjct: 913 -----MENENHRHLLLQLIIKVGDLSNVSRPFDLANRWCAVLCEEFFRQGDLEMARGMQY 967
Query: 377 -SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQS 538
S + DR + EKSQ+GF + PL+++ A ++ P + + +E N + ++S
Sbjct: 968 SSALNDREHLNKEKSQIGFYTSVCLPLYQSVAKVL-PQLESNVVQVESNLETWKS 1021
>UniRef50_A2EIP4 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=2; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1334
Score = 104 bits (249), Expect = 2e-21
Identities = 60/177 (33%), Positives = 99/177 (55%), Gaps = 1/177 (0%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V+ +L + C+IF L E + + ++I ++L+TDM+KH +L D+ V+ +
Sbjct: 1161 VSIGILSKEECNIFSKLQPNEYKN-MWILIIRLILATDMAKHFDILKDINQRVDNGEFD- 1218
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMD- 373
L N DR LE L+ C D+SN ++P L +W +L EEFF+QGD E+ GM+
Sbjct: 1219 ----LQKNENDRYSFLEILIKCGDVSNVSRPFELANKWCDVLCEEFFRQGDLEQASGMEY 1274
Query: 374 ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SP+ DR + KSQ+GF + PL++T A ++ P Q +D ++ N +++ I
Sbjct: 1275 TSPLNDRAHLDKPKSQIGFYTAVCLPLFQTAAKIM-PKLQCNVDQVQSNLAQWKAEI 1330
>UniRef50_A7SVX8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 844
Score = 103 bits (247), Expect = 3e-21
Identities = 59/181 (32%), Positives = 99/181 (54%), Gaps = 8/181 (4%)
Frame = +2
Query: 17 VAFKLL-QNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVA 193
+AFKL ++D +IF NL EE R T+R+ +IDMV++T+M++H L+ + ++ +
Sbjct: 657 LAFKLTARDDKSNIFSNLDVEEFR-TVRQAIIDMVMATEMTRHFEHLSKFVNSINKRRSS 715
Query: 194 G------SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRE 355
S L+ +R + L+ CAD++NP +P L K W + EE+F Q D E
Sbjct: 716 STPDSNTSTSTALNTPENRTLIKRMLIKCADIANPARPRYLCKEWAYRIAEEYFSQTDEE 775
Query: 356 REHGMD-ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYY 532
+ G+ + P+ DR + +SQV FIDY V L++ W + + + L +N DY+
Sbjct: 776 KRRGLPVVMPVFDRATCNVPRSQVWFIDYFVSDLYDAWDAFAY--VPETIRHLTDNYDYW 833
Query: 533 Q 535
+
Sbjct: 834 K 834
>UniRef50_A2DJF3 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1006
Score = 102 bits (245), Expect = 5e-21
Identities = 60/176 (34%), Positives = 99/176 (56%), Gaps = 1/176 (0%)
Frame = +2
Query: 14 RVAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVA 193
+VA +++ ND C+IF + +Q + ++I ++L TDM KH S L + ++
Sbjct: 832 QVAIQVVSNDKCNIFSSFDSPLIKQ-IWSLIIALILKTDMGKHHSTLEAINKRLD----- 885
Query: 194 GSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMD 373
G L DN DR ++E ++ C+D+SN ++P L +W +L EEFF+QGD E+ GM+
Sbjct: 886 -EGPLKPDNEQDRFMMMELILKCSDISNVSRPFELADKWCDVLCEEFFRQGDLEKTSGME 944
Query: 374 -ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQS 538
SP+ DR + KSQ+GF ++ PL+ T A + P Q +D + N ++S
Sbjct: 945 YTSPLNDRAHLDKPKSQIGFYTFVCLPLFVTAARAM-PALQVNVDQVNSNLAIWKS 999
>UniRef50_O95263 Cluster: High affinity cAMP-specific and
IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B; n=83;
Euteleostomi|Rep: High affinity cAMP-specific and
IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B - Homo
sapiens (Human)
Length = 885
Score = 100 bits (240), Expect = 2e-20
Identities = 58/186 (31%), Positives = 101/186 (54%), Gaps = 9/186 (4%)
Frame = +2
Query: 11 TRVAFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVE--- 178
T +AF+L D C+IF N+ R TLR+ +IDMVL+T+M+KH + +
Sbjct: 689 TALAFQLTVKDTKCNIFKNIDRNHYR-TLRQAIIDMVLATEMTKHFEHVNKFVNSINKPM 747
Query: 179 TKKVAGSGVLLLD---NYTD-RIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQG 346
++ GS N+ + +I + ++ CAD++NP +PL L W + EE+F Q
Sbjct: 748 AAEIEGSDCECNPAGKNFPENQILIKRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQT 807
Query: 347 DREREHGMD-ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENR 523
D E+ G+ + P+ DR+ +I KSQ+ FIDY + +++ W H A ++ L +N
Sbjct: 808 DEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFAHLPA--LMQHLADNY 865
Query: 524 DYYQSM 541
+++++
Sbjct: 866 KHWKTL 871
>UniRef50_UPI0000519BD4 Cluster: PREDICTED: similar to
phosphodiesterase 8A; n=1; Apis mellifera|Rep: PREDICTED:
similar to phosphodiesterase 8A - Apis mellifera
Length = 820
Score = 100 bits (239), Expect = 2e-20
Identities = 63/182 (34%), Positives = 101/182 (55%), Gaps = 9/182 (4%)
Frame = +2
Query: 17 VAFKL-LQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETK--- 184
+ FKL L +D +IF NL + +Q +R+ VIDM+L+T+M+KH LA T+
Sbjct: 612 LTFKLTLSDDNVNIFKNLERDTYKQ-VRQSVIDMILATEMTKHFEHLAKFMNAFSTRIPE 670
Query: 185 -KVAGSGVLLLDNYT---DRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDR 352
+ GS L L + I V ++ CAD+SNPT+PL W + EE+F Q D
Sbjct: 671 MYIEGSQDLDLSAAILPENVILVKRMIIKCADVSNPTRPLKYCVEWARRIAEEYFSQTDE 730
Query: 353 ERE-HGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDY 529
E++ H + PM DR +I ++Q+GFID+I++ + E W V + +I+ + +N D
Sbjct: 731 EKQLHLPVMMPMFDRITCSIPRAQIGFIDFIINDMVEAWD--VFINMPEIVGFMRQNYDK 788
Query: 530 YQ 535
++
Sbjct: 789 WK 790
>UniRef50_UPI0000E46CDB Cluster: PREDICTED: similar to
phosphodiesterase 9A; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to phosphodiesterase
9A - Strongylocentrotus purpuratus
Length = 526
Score = 99.5 bits (237), Expect = 4e-20
Identities = 55/175 (31%), Positives = 94/175 (53%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAFK+L+ C+IF NL E +Q +R+ +I +L+TDM+KH +L K ++ T +
Sbjct: 272 VAFKILEKPHCNIFKNLSPEIFKQ-VREGIIRCILATDMAKHNEILNGFKDIISTFDFS- 329
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
N + + + + AD+SN +P+ + + W+ L++EFF Q D E+ G+ +
Sbjct: 330 -------NKVHKDLLTKICIKVADISNEARPMDVAEPWIDCLLQEFFNQSDMEKLEGLPV 382
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+P DR T SQ GFI +++ PL+E+ L + I++ + YY M
Sbjct: 383 APFMDREKVTKHTSQTGFIRFVLLPLFESLGLLFPKLDEHIIEPVRTALKYYSEM 437
>UniRef50_Q8CFW8 Cluster: Phosphodiesterase 8B; n=13;
Euteleostomi|Rep: Phosphodiesterase 8B - Mus musculus
(Mouse)
Length = 730
Score = 99.5 bits (237), Expect = 4e-20
Identities = 59/186 (31%), Positives = 99/186 (53%), Gaps = 9/186 (4%)
Frame = +2
Query: 11 TRVAFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKK 187
T + F+L D C+IF N+ R TLR+ +IDMVL+T+M+KH + +
Sbjct: 534 TALVFQLTVKDTKCNIFKNIDRNHYR-TLRQAIIDMVLATEMTKHFEHVNKFVNSINKPL 592
Query: 188 VAGS-GVLLLDNYT------DRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQG 346
A S G N T ++I + ++ CAD++NP +PL L W + EE+F Q
Sbjct: 593 AAESEGSDCECNPTGKNFPENQILIKRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQT 652
Query: 347 DREREHGMD-ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENR 523
D E+ G+ + P+ DR+ +I KSQ+ FIDY + +++ W H A ++ L +N
Sbjct: 653 DEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFAHLPA--LMQHLADNY 710
Query: 524 DYYQSM 541
+++++
Sbjct: 711 KHWKTL 716
>UniRef50_Q6S996 Cluster: Class I phosphodiesterase PDEB1; n=21;
Trypanosomatidae|Rep: Class I phosphodiesterase PDEB1 -
Leishmania major
Length = 940
Score = 99.5 bits (237), Expect = 4e-20
Identities = 58/177 (32%), Positives = 94/177 (53%), Gaps = 1/177 (0%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
+A ++L + D+F L ++ R + ID VL+TDM+KH L+ ++A
Sbjct: 760 LAIEILSDPAADVFEGLSGQDVAYAYRAL-IDCVLATDMAKHADALSRFT------ELAT 812
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SG DN T R V+E L+ D+SN TKP + W + EEF++QGD E+E G+++
Sbjct: 813 SG-FEKDNDTHRRLVMETLIKAGDVSNVTKPFETSRMWAMAVTEEFYRQGDMEKEKGVEV 871
Query: 377 SPMCDR-HNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
PM DR N + + Q+GFID++ + + Q +DT+ NR +Q ++
Sbjct: 872 LPMFDRSKNNELARGQIGFIDFVAGKFFRDIVGNLFHGMQWCVDTVNSNRAKWQEIL 928
>UniRef50_UPI0000E7FF0E Cluster: PREDICTED: similar to cAMP
phosphodiesterase PDE7, partial; n=1; Gallus gallus|Rep:
PREDICTED: similar to cAMP phosphodiesterase PDE7,
partial - Gallus gallus
Length = 482
Score = 99.1 bits (236), Expect = 6e-20
Identities = 52/152 (34%), Positives = 86/152 (56%)
Frame = +2
Query: 14 RVAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVA 193
R A LL+ G ++L E RQ + + D++L+TD+S+ L+ ++ ++
Sbjct: 285 RSAVGLLRESGLFAHMSL---ENRQLMESQIGDLILATDISQQNEYLSMFRSHLDR---- 337
Query: 194 GSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMD 373
G L L++ R +L+ + CAD+ NP + L K+W + EEFF QGD E+++ +
Sbjct: 338 --GDLCLEDANHRHFILQMALKCADICNPCRTWELSKQWSEKVTEEFFHQGDIEKKYHLG 395
Query: 374 ISPMCDRHNATIEKSQVGFIDYIVHPLWETWA 469
+SP+CDR TI Q+GF+ Y+V PL+ WA
Sbjct: 396 VSPLCDRQTETIANIQIGFMTYLVEPLFAEWA 427
Score = 81.4 bits (192), Expect = 1e-14
Identities = 45/138 (32%), Positives = 76/138 (55%)
Frame = +2
Query: 14 RVAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVA 193
R A LL+ G ++L E RQ + + D++L+TD+S+ L+ ++ ++
Sbjct: 88 RSAVGLLRESGLFAHMSL---ENRQLMESQIGDLILATDISQQNEYLSMFRSHLDR---- 140
Query: 194 GSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMD 373
G L L++ R +L+ + CAD+ NP + L K+W + EEFF QGD E+++ +
Sbjct: 141 --GDLCLEDANHRHFILQMALKCADICNPCRTWELSKQWSEKVTEEFFHQGDIEKKYHLG 198
Query: 374 ISPMCDRHNATIEKSQVG 427
+SP+CDR TI Q+G
Sbjct: 199 VSPLCDRQTETIANIQIG 216
>UniRef50_A2ENJ2 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1087
Score = 97.5 bits (232), Expect = 2e-19
Identities = 55/174 (31%), Positives = 98/174 (56%), Gaps = 1/174 (0%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
+A ++ + +IF L+ E+ ++ + +I+++L+TDM+KH + L ++ +++
Sbjct: 909 MAISVISKEETNIFAKLNAEQYKK-IWTTIINLILATDMAKHFTFLKEINGIMD------ 961
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMD- 373
G L +DN D LE ++ CAD+SN ++P L +W +L EEFF+QGD E GM
Sbjct: 962 EGKLSIDNPDDVSYYLELILKCADISNVSRPFELADKWCDVLCEEFFRQGDLEMAQGMQY 1021
Query: 374 ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQ 535
S + DR + KSQ+GF ++ PL+E A + P Q +D + N + ++
Sbjct: 1022 TSDLNDRSHLNKPKSQIGFYTFVCLPLFEAAARAM-PPLQCNVDQIRSNLEVWK 1074
>UniRef50_Q388U6 Cluster: 3', 5'-cyclic nucleotide
phosphodiesterase, putative; n=2; Trypanosoma
brucei|Rep: 3', 5'-cyclic nucleotide phosphodiesterase,
putative - Trypanosoma brucei
Length = 620
Score = 96.7 bits (230), Expect = 3e-19
Identities = 56/152 (36%), Positives = 76/152 (50%)
Frame = +2
Query: 23 FKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSG 202
F+L++N +I EE R R VIDMVL+TDMS H + K + K+
Sbjct: 451 FELMRNPALNILACFSEEHWRD-FRNTVIDMVLATDMSLHEKYMTQFKRRLSEKRP---- 505
Query: 203 VLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISP 382
D+ L + AD+SN +PLPLY +W + +EF+ QGDRER GM SP
Sbjct: 506 ---FTEDCDQNLALAMALKLADISNCCRPLPLYLKWSERVSDEFYTQGDRERSLGMSCSP 562
Query: 383 MCDRHNATIEKSQVGFIDYIVHPLWETWADLV 478
DR I + Q FI+YI P E A+ +
Sbjct: 563 FMDRQTPMIAEGQTSFINYIFIPFLEVMAEFL 594
>UniRef50_Q13946 Cluster: High affinity cAMP-specific 3',5'-cyclic
phosphodiesterase 7A; n=73; Euteleostomi|Rep: High
affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
- Homo sapiens (Human)
Length = 482
Score = 96.7 bits (230), Expect = 3e-19
Identities = 53/152 (34%), Positives = 87/152 (57%)
Frame = +2
Query: 14 RVAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVA 193
R A LL+ G +F +L E RQ + + ++L+TD+S+ L+ ++ ++
Sbjct: 287 RSAVGLLRESG--LFSHL-PLESRQQMETQIGALILATDISRQNEYLSLFRSHLDR---- 339
Query: 194 GSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMD 373
G L L++ R VL+ + CAD+ NP + L K+W + EEFF QGD E+++ +
Sbjct: 340 --GDLCLEDTRHRHLVLQMALKCADICNPCRTWELSKQWSEKVTEEFFHQGDIEKKYHLG 397
Query: 374 ISPMCDRHNATIEKSQVGFIDYIVHPLWETWA 469
+SP+CDRH +I Q+GF+ Y+V PL+ WA
Sbjct: 398 VSPLCDRHTESIANIQIGFMTYLVEPLFTEWA 429
>UniRef50_UPI00015B4893 Cluster: PREDICTED: similar to camp-specific
3,5-cyclic phosphodiesterase; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to camp-specific
3,5-cyclic phosphodiesterase - Nasonia vitripennis
Length = 1229
Score = 96.3 bits (229), Expect = 4e-19
Identities = 45/152 (29%), Positives = 88/152 (57%), Gaps = 1/152 (0%)
Frame = +2
Query: 92 LRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADL 271
L++ + ++L+TD+++ L K ++ ++ L ++ R +L+ + CAD+
Sbjct: 390 LQRHISSLILATDITRQQEFLTRFKRYLDERE------LDMEQPEHRHFILQIALKCADI 443
Query: 272 SNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATIEKSQVGFIDYIVHP 451
SNP +P + ++W + EEFF+QGD ER+ + ++ +CDRH +I K Q GF ++V P
Sbjct: 444 SNPCRPWDISRKWSYKVCEEFFRQGDYERQLNLPVTALCDRHTTSIPKIQAGFFKFVVLP 503
Query: 452 LWETWADLVHPD-AQDILDTLEENRDYYQSMI 544
L+E W + D ++ ++ L N+ +++ MI
Sbjct: 504 LYEEWHRFLDDDFSRSLMRHLRANQQHWELMI 535
>UniRef50_UPI0000DB6B8B Cluster: PREDICTED: similar to
phosphodiesterase 7A isoform a; n=1; Apis mellifera|Rep:
PREDICTED: similar to phosphodiesterase 7A isoform a -
Apis mellifera
Length = 1148
Score = 96.3 bits (229), Expect = 4e-19
Identities = 46/155 (29%), Positives = 87/155 (56%), Gaps = 1/155 (0%)
Frame = +2
Query: 83 RQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHC 262
R L++ + ++L+TD+++ L K ++ +L + DR +L+ + C
Sbjct: 192 RPELQRHISSLILATDITRQQEFLIRFKHYLD------ENLLEMKRADDRHFILQIALKC 245
Query: 263 ADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATIEKSQVGFIDYI 442
AD+SNP +P + ++W + EEFF+QGD ER + ++P+CDRH +I K Q GF ++
Sbjct: 246 ADISNPCRPWDISQKWSHKVCEEFFRQGDYERRLNLPVTPLCDRHTTSIPKIQAGFFKFV 305
Query: 443 VHPLWETWADLVHPD-AQDILDTLEENRDYYQSMI 544
V PL+E W + + +++ L N+ ++++I
Sbjct: 306 VTPLYEEWHRFLGDGLSVSLMEHLRANQKKWEALI 340
>UniRef50_UPI0000D577EC Cluster: PREDICTED: similar to CG32648-PA;
n=2; Coelomata|Rep: PREDICTED: similar to CG32648-PA -
Tribolium castaneum
Length = 938
Score = 96.3 bits (229), Expect = 4e-19
Identities = 54/179 (30%), Positives = 101/179 (56%), Gaps = 4/179 (2%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAF++L+N+ C+IF + E+ + T+R+ +I +L+TDM++H +L + + +
Sbjct: 323 VAFRILENEDCNIFKSFKSEDFK-TVREGIIRCILATDMARHNEILTNFREITPNF---- 377
Query: 197 SGVLLLDNYTDRIQV---LENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHG 367
+Y D+ V L+ +D+SN +P+ + + W+ L++EFF+Q D E+ G
Sbjct: 378 -------DYNDKAHVNLLCMVLIKVSDISNEARPMDVAEPWLDRLLQEFFKQSDAEKLEG 430
Query: 368 MDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQD-ILDTLEENRDYYQSM 541
+ ++P DR T SQ FI +++ PL+E DL+ + QD I+ + E +YY+ +
Sbjct: 431 LPVTPFMDREKITKPSSQCSFIGFVLLPLFEALGDLL-TELQDLIVQPVREALEYYRRL 488
>UniRef50_A0EBQ7 Cluster: Chromosome undetermined scaffold_88, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_88, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 744
Score = 96.3 bits (229), Expect = 4e-19
Identities = 55/173 (31%), Positives = 97/173 (56%), Gaps = 2/173 (1%)
Frame = +2
Query: 23 FKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSG 202
F +L+++ +I N+++ + + RK ++++L TD+ KH LL K + + S
Sbjct: 541 FHVLKDEKANILKNINDVDYKG-FRKYCLNLILDTDLQKHFPLLNKFKNFLALGSDSQS- 598
Query: 203 VLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISP 382
D T ++ +L + CAD+ + K L L+K W ++EEFF QGD E + G+ ++P
Sbjct: 599 ----DEQT-KLLILSIAIKCADVGHGAKQLNLHKIWSRRIIEEFFLQGDLEAQVGIQVTP 653
Query: 383 MCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPD--AQDILDTLEENRDYYQ 535
MCDR + ++ KSQ GF+ IV PL++ + + + + Q LD + N Y+Q
Sbjct: 654 MCDR-SQSVTKSQEGFLKAIVWPLFDAFGEFLKNENFRQTCLDQISVNIQYWQ 705
>UniRef50_A0CB76 Cluster: Chromosome undetermined scaffold_163,
whole genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_163,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 619
Score = 95.9 bits (228), Expect = 5e-19
Identities = 48/150 (32%), Positives = 83/150 (55%)
Frame = +2
Query: 95 RKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLS 274
R+ I+M+LSTD + H LK + + D+ + L+H AD+S
Sbjct: 468 REKSINMILSTDNAMHGKDYNKLKARLASNDFDPGS-------KDKGICFDTLLHAADIS 520
Query: 275 NPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATIEKSQVGFIDYIVHPL 454
NP KP+ Y++W ++ EF+ QGDRE+E G+ ++ +CDR + KSQ+GFID++V P
Sbjct: 521 NPFKPMKNYEQWTFRVLGEFWHQGDREKELGLPVTMLCDRRTTNVAKSQIGFIDFMVLPY 580
Query: 455 WETWADLVHPDAQDILDTLEENRDYYQSMI 544
+ T + ++ P + ++ + EN+ + I
Sbjct: 581 YNTLSQIL-PQLSEFIEQITENKKAWAEKI 609
>UniRef50_Q16J23 Cluster: Camp-specific 3,5-cyclic
phosphodiesterase; n=2; Culicidae|Rep: Camp-specific
3,5-cyclic phosphodiesterase - Aedes aegypti
(Yellowfever mosquito)
Length = 872
Score = 94.3 bits (224), Expect = 2e-18
Identities = 48/170 (28%), Positives = 93/170 (54%), Gaps = 3/170 (1%)
Frame = +2
Query: 44 GCDIFVNLHEEEQ--RQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLD 217
GC + + E+ Q R L K + ++L+TD+++ ++ + + L +
Sbjct: 247 GCLLESGVAEQIQGIRPELEKQISSLILATDITRQQEFISQFRDYLS------HDTLDMR 300
Query: 218 NYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRH 397
N R +L+ + CAD+SNP +P + K+W + EEFF+QGD ER+ + ++ +CDRH
Sbjct: 301 NKEHRHFILQIALKCADISNPCRPWDISKKWSLKVCEEFFRQGDYERQLNLPVTSLCDRH 360
Query: 398 NATIEKSQVGFIDYIVHPLWETWADLVHPD-AQDILDTLEENRDYYQSMI 544
+ ++ K Q GF ++V PL + W + D + +++ L+ N+ ++S +
Sbjct: 361 STSVPKIQTGFFKFVVTPLMDEWHRFLKTDLSYNMMHHLKYNQIQWESKL 410
>UniRef50_A2DF08 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1040
Score = 94.3 bits (224), Expect = 2e-18
Identities = 50/153 (32%), Positives = 89/153 (58%), Gaps = 1/153 (0%)
Frame = +2
Query: 14 RVAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVA 193
+VA ++ + C+IF L+ + R T+ +I ++LSTDM+KH +L + +++
Sbjct: 862 QVAIGVISKEECNIFSALNAGDNR-TMWMTIISLILSTDMAKHFEILKNFNAIMD----- 915
Query: 194 GSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMD 373
+G ++N RI +++ L+ AD+SN ++P + RW +L EEFF+QGD E GM+
Sbjct: 916 -AGEFSMENKDHRILLMQLLLKTADISNVSRPFDIANRWCDILCEEFFRQGDLEMAQGME 974
Query: 374 -ISPMCDRHNATIEKSQVGFIDYIVHPLWETWA 469
S + D+ + KSQ+GF ++ PL++ A
Sbjct: 975 YTSDLNDKAHLDKPKSQIGFYTFVCLPLYQALA 1007
>UniRef50_A7SVS5 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 496
Score = 93.1 bits (221), Expect = 4e-18
Identities = 50/175 (28%), Positives = 97/175 (55%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAF +++ D +I N+ E ++ +R+ +I +LSTDM++H +L K +++
Sbjct: 301 VAFDIMKQDKSNILQNVSAETFKK-IREGMIKCILSTDMARHSDILNKFKELLK------ 353
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SG D+ + +++ ++ +D+SN +P+ + + W+ L++EFF Q D E+ G+ +
Sbjct: 354 SG-FKFDDEAHKSMLMQIMIKVSDVSNEARPMDVAEPWLDCLLQEFFIQSDVEKLEGLPV 412
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+P DR T +Q+GFI +++ PL+E +L I+ + + DYY M
Sbjct: 413 APFMDRDKVTKPSAQIGFIKFVLVPLFEALGELFPILEDHIVSPVRKALDYYVGM 467
>UniRef50_A0EGK4 Cluster: Chromosome undetermined scaffold_95, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_95, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 756
Score = 92.3 bits (219), Expect = 7e-18
Identities = 54/176 (30%), Positives = 94/176 (53%), Gaps = 2/176 (1%)
Frame = +2
Query: 23 FKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSG 202
F++LQ + ++ NL +Q+ RK ++++L TD++KH L+ + ++ +
Sbjct: 561 FQILQQEQFNLIQNLGLPDQKG-FRKYCLNLILDTDLTKHFQLMNRFQNYLDLSE----- 614
Query: 203 VLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISP 382
TD+ V+ + CAD+ + K L ++K W ++EEFF QGD E + ISP
Sbjct: 615 ----SQVTDKSLVMSICIKCADVGHGAKQLKMHKLWSRRIIEEFFLQGDLEDYLKVPISP 670
Query: 383 MCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQD--ILDTLEENRDYYQSMI 544
MCDR + + KSQ GF+ IV P++ +A L+ + + L + +N Y+Q I
Sbjct: 671 MCDRKQSVV-KSQEGFLKAIVLPMFNAFAKLLQNEKVNSICLSQIHQNLQYWQQQI 725
>UniRef50_A2D762 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=2; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1081
Score = 91.9 bits (218), Expect = 9e-18
Identities = 52/157 (33%), Positives = 88/157 (56%), Gaps = 1/157 (0%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VA LL + ++F ++ E QRQ L +I ++L+TDM+ H L+ D T ++A
Sbjct: 907 VAISLLTKEEYNLFHSVDLEHQRQ-LWTTIIQLILATDMANHFKLVKD------TNEIAD 959
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
++ R+ ++ L+ D+SN ++P + +W +L EEFF+QGD E+ G+ +
Sbjct: 960 KAEFDIEKPEHRLLSMKLLLKVGDISNVSRPFQIADKWCDILCEEFFRQGDNEKSLGIGL 1019
Query: 377 -SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHP 484
SP+ DR N KSQ+GF +++ PL++ A L P
Sbjct: 1020 TSPLNDRLNNDKPKSQIGFYNFVCLPLYQVVAKLFPP 1056
>UniRef50_Q6NNF2 Cluster: SD02170p; n=9; Diptera|Rep: SD02170p -
Drosophila melanogaster (Fruit fly)
Length = 914
Score = 91.5 bits (217), Expect = 1e-17
Identities = 52/156 (33%), Positives = 85/156 (54%), Gaps = 2/156 (1%)
Frame = +2
Query: 17 VAFKL-LQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVA 193
+ FKL L +D +IF NL ++E ++ R +IDM+L+T+M++H LA ++ ++
Sbjct: 718 ITFKLTLGDDKINIFKNL-DKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGGEEPR 776
Query: 194 GSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMD 373
D T I + L+ AD+SNP +P+ W + EE+F Q D E++ +
Sbjct: 777 DHNPQT-DEETS-ILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQRHLP 834
Query: 374 I-SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLV 478
I PM DR +I KSQ+GFI+YI+ + W +
Sbjct: 835 IVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWESFI 870
>UniRef50_A2EY05 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 922
Score = 91.5 bits (217), Expect = 1e-17
Identities = 48/173 (27%), Positives = 95/173 (54%), Gaps = 1/173 (0%)
Frame = +2
Query: 5 FGTRVAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETK 184
F +A K+LQ D ++F +L++ + + +I ++L+TDM+KH L+ ++ + ++
Sbjct: 745 FHCAMAIKILQEDDTNLFYSLNDNDL-SNVWSWIIHLILATDMAKHFKLIKEMNDTISSR 803
Query: 185 KVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREH 364
L +++ DR+ +E ++ AD+SN ++P + +W +L +EF++QGD E++H
Sbjct: 804 N------LDMESENDRLCCMEMIMKVADISNVSRPFFIADKWCDVLQDEFWRQGDMEKQH 857
Query: 365 GMDI-SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEEN 520
+ SP+ R K Q+GF + PL+ A + P+ LD++ N
Sbjct: 858 ELSYSSPLMSREGQNKAKGQIGFYKAVCIPLYSLVA-RIFPELNKSLDSVNAN 909
>UniRef50_A0DF61 Cluster: Chromosome undetermined scaffold_49, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_49, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 768
Score = 90.6 bits (215), Expect = 2e-17
Identities = 52/173 (30%), Positives = 93/173 (53%), Gaps = 2/173 (1%)
Frame = +2
Query: 23 FKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSG 202
F++L C+I NL E + RK ++++L TD+++H L+ + + +
Sbjct: 572 FQVLTQSNCNIIENLSINEIKG-FRKYCLNLILDTDLTRHFQLMNKFQNYLNVNESPA-- 628
Query: 203 VLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISP 382
D+ ++ + CAD+ + K L L+K W ++EEFF QGD E + ISP
Sbjct: 629 -------VDQQLIMSIGIKCADVGHGAKELKLHKLWSRRIVEEFFLQGDLENYLKVPISP 681
Query: 383 MCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPD--AQDILDTLEENRDYYQ 535
MCDR N + KSQ GF+ IV P++E ++ ++ + + +D +++N +Y+Q
Sbjct: 682 MCDR-NQNVSKSQEGFLKAIVLPMFEAFSTILKNENIQKTCVDQVKQNIEYWQ 733
>UniRef50_Q4SPD6 Cluster: Chromosome 16 SCAF14537, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 16 SCAF14537, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 560
Score = 89.8 bits (213), Expect = 4e-17
Identities = 42/146 (28%), Positives = 82/146 (56%)
Frame = +2
Query: 104 VIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPT 283
+I ++L+TDM++H +L K V+ + + ++++ L+ C D+SN
Sbjct: 411 IITLILATDMARHGEILDSFKQKVDNFDFTN------EEHVTCLKMV--LIKCCDISNEV 462
Query: 284 KPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATIEKSQVGFIDYIVHPLWET 463
+P + + WV L+EE+F Q DRE+ G+ ++P DR T +Q+GFI +++ P++ET
Sbjct: 463 RPTEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKPTAQIGFIKFVLIPMFET 522
Query: 464 WADLVHPDAQDILDTLEENRDYYQSM 541
L + ++ L ++RD+Y+ +
Sbjct: 523 VMKLFPQIEEIMVQPLRDSRDHYEEL 548
>UniRef50_Q54HY3 Cluster: Putative uncharacterized protein Pde4;
n=2; Dictyostelium discoideum|Rep: Putative
uncharacterized protein Pde4 - Dictyostelium discoideum
AX4
Length = 771
Score = 89.4 bits (212), Expect = 5e-17
Identities = 37/92 (40%), Positives = 57/92 (61%)
Frame = +2
Query: 194 GSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMD 373
GS + L N DR+ +++ + CAD+SNP+KP LY W + EF++QGD+E+E MD
Sbjct: 569 GSSIFLNSNKKDRLLLMKISIKCADISNPSKPWNLYTNWSNRVTSEFYKQGDKEKESNMD 628
Query: 374 ISPMCDRHNATIEKSQVGFIDYIVHPLWETWA 469
+S DR+ K Q+ FI+ V P++E W+
Sbjct: 629 VSAFMDRNKPATTKCQINFINIFVAPIYEIWS 660
Score = 36.7 bits (81), Expect = 0.35
Identities = 18/54 (33%), Positives = 32/54 (59%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVET 181
AF ++ I + L + R+ +R+ +I +VLSTDM+KH +L+ K+M +
Sbjct: 417 AFIIMNEPESGILLKL-SDSVRKEIRETIIALVLSTDMAKHFNLVGRFKSMANS 469
>UniRef50_Q4D500 Cluster: Phosphodiesterase, putative; n=3;
Trypanosoma cruzi|Rep: Phosphodiesterase, putative -
Trypanosoma cruzi
Length = 708
Score = 89.4 bits (212), Expect = 5e-17
Identities = 53/152 (34%), Positives = 85/152 (55%), Gaps = 3/152 (1%)
Frame = +2
Query: 23 FKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSG 202
F+L++N +I + E++Q++ +R+ VI+MVL+TDMS H +A +E
Sbjct: 542 FELMKNPRFNILESFSEDQQKE-IRETVIEMVLATDMSLHGKHIAHFNDRLEEHA----- 595
Query: 203 VLLLDNYTDRIQ---VLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMD 373
++T+R L + AD+SN +PL +Y +W + L +EF+ QGDRER G+
Sbjct: 596 -----SFTERENQNLALVMALKMADISNCGRPLEIYLKWSSKLSDEFYLQGDRERNLGVQ 650
Query: 374 ISPMCDRHNATIEKSQVGFIDYIVHPLWETWA 469
SP DR + K Q+ FI+YI+ P +E A
Sbjct: 651 CSPFMDRMEPALAKGQILFINYIIIPFFEKMA 682
>UniRef50_A7RXZ4 Cluster: Predicted protein; n=3; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 367
Score = 88.6 bits (210), Expect = 8e-17
Identities = 48/151 (31%), Positives = 83/151 (54%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
AF LL +D F+ + + R + I+ +L+TD+ +H +L+D K A
Sbjct: 206 AFTLLMSDPKYNFLCELSPAEFKRFRFLAIEAILATDLKRHFDILSDFNA-----KTAEG 260
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS 379
GV D+ DR+ L+ + +D+S P+K ++ W ++EEF++QGD ER GM +S
Sbjct: 261 GVNW-DSEADRLLTLQFCIKMSDISGPSKRRDIHTLWTERIVEEFYEQGDDERARGMAVS 319
Query: 380 PMCDRHNATIEKSQVGFIDYIVHPLWETWAD 472
P DR + + Q FI+++V PL+ ++A+
Sbjct: 320 PYMDRQQPHVAQLQDSFINHLVAPLYNSYAN 350
>UniRef50_Q8I0P7 Cluster: Probable 3',5'-cyclic phosphodiesterase
pde-3; n=4; Caenorhabditis|Rep: Probable 3',5'-cyclic
phosphodiesterase pde-3 - Caenorhabditis elegans
Length = 578
Score = 88.2 bits (209), Expect = 1e-16
Identities = 48/145 (33%), Positives = 84/145 (57%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
++KLL NL E ++ R +V++ +L+TD+ +H ++ M T+++
Sbjct: 358 SWKLLNKPENHFIENLDPAEMKR-FRYLVLEYILATDLKQHFEII-----MTFTERLTEI 411
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS 379
V + TDR+ + + L+ AD+++PTKP L+++W + EEF++QGD ER G+ I+
Sbjct: 412 DVQV---ETDRLLIGKLLIKMADINSPTKPYGLHRQWTDRICEEFYEQGDDERRRGLPIT 468
Query: 380 PMCDRHNATIEKSQVGFIDYIVHPL 454
P DR +A + K Q FI ++V PL
Sbjct: 469 PYMDRGDAQVAKLQDSFIAHVVSPL 493
>UniRef50_A2FKH2 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1086
Score = 87.4 bits (207), Expect = 2e-16
Identities = 48/169 (28%), Positives = 93/169 (55%), Gaps = 1/169 (0%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
+A ++ + +IF +L+ E ++ + ++I+++L TDM+KH + L + + + +
Sbjct: 888 IAIDIISKEETNIFASLNPAEYKK-MWSLIINLILITDMAKHFTFLKEFNGLFDAGEWKP 946
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMD- 373
+N + +++ L+ C D+SN ++P L +W +L EEFF+QGD E+ GM+
Sbjct: 947 K-----ENPQHFLMLMQMLLKCGDISNVSRPFELADKWCDVLCEEFFRQGDLEQAQGMNY 1001
Query: 374 ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEEN 520
S + DR + KSQ+GF ++ PL++ A + P Q +D + N
Sbjct: 1002 TSDLNDRAHLDKPKSQIGFYTFVCLPLYQATAKAI-PKLQVNVDQVNSN 1049
>UniRef50_A2FBN7 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1090
Score = 87.0 bits (206), Expect = 2e-16
Identities = 48/176 (27%), Positives = 98/176 (55%), Gaps = 1/176 (0%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VA +L C++F ++ EE Q+Q + ++I ++L+TDM+ H ++ ++
Sbjct: 909 VAISILTRKECNLFHSITEEAQKQ-MWTLIIKLILATDMAFHFKMVKAATEFMD------ 961
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+G ++ R+ + ++ AD+SN ++P + +W +L EEFF+QGD+E+ +
Sbjct: 962 AGPFNPNDPEQRLIAFQLVLKTADISNVSRPFKVADKWCDVLCEEFFRQGDKEKAQAFGL 1021
Query: 377 -SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
SP+ DR N KSQ+GF +++ PL+ + P + L++++ N + ++S+
Sbjct: 1022 TSPLNDRDNPDKPKSQIGFYNFVCIPLYSV-ISRIFPKFEVNLNSVKSNLEVWKSL 1076
>UniRef50_A2DYU6 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1091
Score = 87.0 bits (206), Expect = 2e-16
Identities = 51/169 (30%), Positives = 94/169 (55%), Gaps = 1/169 (0%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V+ +L +D ++ +L EE+ ++ + +M+I +L+TDM+KH ++ K +V+
Sbjct: 897 VSIDILSDDSYNLIYSLSEEDTKK-MWQMMIQNILATDMAKHFEMIKTTKALVD------ 949
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+G L+ R + L+ AD+SN ++P L W +L EF++QGD E+ G+ +
Sbjct: 950 AGEFDLNKEEHRRIAMSLLLKVADISNVSRPFELADNWCDILNVEFYRQGDLEKATGIGL 1009
Query: 377 -SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEEN 520
SP+ DR + KSQ+GF +++ PL+ A + P Q D+++ N
Sbjct: 1010 TSPLNDREHPDKPKSQIGFYNFVCLPLYNVVA-TIFPKLQVNADSVKSN 1057
>UniRef50_Q23917 Cluster: 3',5'-cyclic-nucleotide phosphodiesterase
regA; n=2; Dictyostelium discoideum|Rep:
3',5'-cyclic-nucleotide phosphodiesterase regA -
Dictyostelium discoideum (Slime mold)
Length = 793
Score = 87.0 bits (206), Expect = 2e-16
Identities = 48/174 (27%), Positives = 89/174 (51%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
+ FK+L+N C+I L+E++ ++ LR+ V+ ++L+TDM H + +
Sbjct: 563 LTFKILRNSECNILEGLNEDQYKE-LRRSVVQLILATDMQNHFEHTNKFQHHLNNLPFDR 621
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ DR +L L+ C D+SN +P L W + +EFFQQ E G +
Sbjct: 622 N------KKEDRQMILNFLIKCGDISNIARPWHLNFEWSLRVSDEFFQQSHYETICGYPV 675
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQS 538
+P D+ T + FID++ PL+++ A + ++Q +L + +NR+ +Q+
Sbjct: 676 TPFMDKTKTTRARIAADFIDFVASPLFQSMAKFL-KESQFLLKVISKNRENWQA 728
>UniRef50_Q7PQX7 Cluster: ENSANGP00000010843; n=6; Coelomata|Rep:
ENSANGP00000010843 - Anopheles gambiae str. PEST
Length = 547
Score = 85.0 bits (201), Expect = 1e-15
Identities = 52/174 (29%), Positives = 99/174 (56%), Gaps = 1/174 (0%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
+AF+LL++ C+IF N+ +E + +R+ +I +L+TDM++H +L + T +
Sbjct: 176 IAFRLLEHPECNIFRNMSKEMYKD-VREGIIRCILATDMARHNEILTQFQEA--TPEFDY 232
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
S + +T+ + ++ L+ AD+SN +P+ + + WV L++EFF Q E+ G+ +
Sbjct: 233 SNKV----HTNLLCMV--LIKVADISNEARPMDVAEPWVDRLLQEFFAQSAAEKSEGLPV 286
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDT-LEENRDYYQ 535
+P D + SQV FI ++ PL+E +L+ P+ D++ T + DYY+
Sbjct: 287 TPFMDPDKVSKPGSQVRFIGLVLLPLFEALGELL-PELTDLIITPVRVALDYYR 339
>UniRef50_A2F408 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1086
Score = 84.6 bits (200), Expect = 1e-15
Identities = 49/157 (31%), Positives = 87/157 (55%), Gaps = 1/157 (0%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VA ++ + ++F L ++ + + +I+++L+TDMSKH +LL + K + + K
Sbjct: 885 VAIGIISKEETNLFAKLKSQDFK-FMWTTIIELILATDMSKHFTLLKEFKALNDEGKWDK 943
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMD- 373
+ + R+++++ L+ AD+SN ++P L RW +L EEFF+QGD E GM
Sbjct: 944 TQPDI------RLRMMKLLLKTADISNVSRPFELADRWCDVLCEEFFRQGDLEMASGMQY 997
Query: 374 ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHP 484
S + DR + KSQ+GF ++ PL++ A P
Sbjct: 998 TSDLNDREHLDKPKSQIGFYTFVCLPLYQATAQAFPP 1034
>UniRef50_A2G2M9 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=2; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1136
Score = 84.2 bits (199), Expect = 2e-15
Identities = 50/173 (28%), Positives = 94/173 (54%), Gaps = 1/173 (0%)
Frame = +2
Query: 5 FGTRVAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETK 184
F VA ++L ++F +L+ +E + K +I ++L+TDM+ H L+ +E
Sbjct: 929 FHCTVAIRILSQPETNLFHSLNTKELT-VIWKWIIHLILATDMAFHFKLIKQGNEALE-- 985
Query: 185 KVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREH 364
+GV+ L R+ +E ++ +D+SN ++P +W +L EEF++QGD+E+E
Sbjct: 986 ----AGVINLKEEAHRLMCMELVMKVSDISNVSRPFKYADKWCEVLSEEFWRQGDKEKEL 1041
Query: 365 GMDIS-PMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEEN 520
G+ S P+ +R K QVGF +++ PL+ T + P+ L++++ N
Sbjct: 1042 GLPYSGPLMNREGQNKPKGQVGFYNFVCLPLY-TLIARIFPELTVNLESVKSN 1093
>UniRef50_A2ERL4 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=2; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1180
Score = 84.2 bits (199), Expect = 2e-15
Identities = 42/149 (28%), Positives = 83/149 (55%), Gaps = 1/149 (0%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
+A +++ ++ ++ L+++E + + ++I +L+TDM++H +L + +
Sbjct: 889 IAIQIMSHEETNLLAALNQDEYIE-IWSLIIQYILATDMARHFEILKRFNDIYD------ 941
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMD- 373
G + + R+ +L ++ C D+SN ++P L RW +L EEFF+QGD E+ GM
Sbjct: 942 GGDFTMQRHDHRVMLLYMILKCGDISNVSRPFELADRWCDVLCEEFFRQGDLEQAQGMAY 1001
Query: 374 ISPMCDRHNATIEKSQVGFIDYIVHPLWE 460
S + DR + KSQ+GF Y+ P+++
Sbjct: 1002 TSDLNDRSHLDKAKSQIGFYTYVTLPMFQ 1030
>UniRef50_Q9N2V9 Cluster: Probable 3',5'-cyclic phosphodiesterase
pde-6; n=3; Caenorhabditis|Rep: Probable 3',5'-cyclic
phosphodiesterase pde-6 - Caenorhabditis elegans
Length = 760
Score = 84.2 bits (199), Expect = 2e-15
Identities = 57/178 (32%), Positives = 95/178 (53%), Gaps = 3/178 (1%)
Frame = +2
Query: 17 VAFKL-LQ-NDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKV 190
+AF+L LQ N +IF +L EE Q +R +++MVL+TD+S+H LA M T
Sbjct: 578 LAFQLTLQHNANVNIFSSLSREEFIQ-MRHAMVEMVLATDISRHFEYLAKFNKMHVTD-- 634
Query: 191 AGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGM 370
V T+ + + + LV CAD+SNP + L +RW ++EE+F+Q E+E G+
Sbjct: 635 ----VPEEQRDTNSLTICDMLVKCADISNPAREWGLCQRWAHRIVEEYFEQTREEKEKGL 690
Query: 371 DIS-PMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
++ + DR+ + +Q GFID + T+ + ++ D LE N + ++ M
Sbjct: 691 PVTMEVFDRNTCNVPITQCGFIDMFAREAFATFTEFA--KLGELSDQLESNYEKWKVM 746
>UniRef50_A4RUJ3 Cluster: Predicted protein; n=1; Ostreococcus
lucimarinus CCE9901|Rep: Predicted protein -
Ostreococcus lucimarinus CCE9901
Length = 614
Score = 83.8 bits (198), Expect = 2e-15
Identities = 54/171 (31%), Positives = 85/171 (49%), Gaps = 4/171 (2%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
AF LL+ + + EQ L+K + M++ TDM H L + +E ++ +
Sbjct: 431 AFSLLKKHA--VLAKFTDSEQSD-LKKWLQKMIMYTDMEFHGELTQRMLKEIEDEQDEET 487
Query: 200 GVLLLDNYTDRIQV-LENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ I V L +HCAD+SNP +P L W + EF++QGDR+R+ GM +
Sbjct: 488 NSIKPIKQWQNIWVPLAFALHCADISNPARPYELALAWAQAVTAEFYKQGDRQRKLGMRV 547
Query: 377 SPMCDRH---NATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEEN 520
P DR A+ + +Q+GFI +V P + ++ +LDTLEEN
Sbjct: 548 EPFMDRSLAGPASTQSNQLGFIKLVVKPSLCVLEAFMPAASRHLLDTLEEN 598
>UniRef50_Q16VA1 Cluster: High-affinity cgmp-specific 3,5-cyclic
phosphodiesterase; n=1; Aedes aegypti|Rep: High-affinity
cgmp-specific 3,5-cyclic phosphodiesterase - Aedes
aegypti (Yellowfever mosquito)
Length = 1022
Score = 83.8 bits (198), Expect = 2e-15
Identities = 49/176 (27%), Positives = 95/176 (53%), Gaps = 1/176 (0%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
+AF+LL++ C+IF N+ ++ + +R+ +I +L+TDM++H +L +
Sbjct: 181 IAFRLLEHPDCNIFRNMSKDLYKD-VREGIIRCILATDMARHNEILTQFQE--------A 231
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ V +N + L+ AD+SN +P+ + + W+ L++EFF Q E+ G+ +
Sbjct: 232 TPVFDYNNKVHTNLLCMVLIKVADISNEARPMDVAEPWLDRLLQEFFAQSAAEKSEGLPV 291
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDT-LEENRDYYQSM 541
+P D + SQV FI ++ PL+E +L+ P+ D++ T + DYY+ +
Sbjct: 292 TPFMDPDKVSKPGSQVRFIGLVLLPLFEALGELL-PELTDLIITPVRVALDYYKKL 346
>UniRef50_A4HHP3 Cluster: Putative uncharacterized protein; n=3;
Leishmania|Rep: Putative uncharacterized protein -
Leishmania braziliensis
Length = 734
Score = 83.8 bits (198), Expect = 2e-15
Identities = 54/173 (31%), Positives = 88/173 (50%), Gaps = 2/173 (1%)
Frame = +2
Query: 23 FKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSG 202
F+LL+N +IF L +EQR +R+ +++MVL+TDM H + + + + S
Sbjct: 542 FELLRNPRYNIFATL-SDEQRLLVRETILEMVLATDMGNHARIFKNFQVRMSEATEWHS- 599
Query: 203 VLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISP 382
D L + AD+SN +P +Y W + +EF+ QGD ER+ + ISP
Sbjct: 600 -----KKEDVRLALSMSIKMADISNCARPNHIYAEWAKNISKEFYLQGDAERKLNLSISP 654
Query: 383 MCDRHNATIE--KSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQ 535
DR E K QV F+ YIV P+ E + L+ P ++ +N++Y++
Sbjct: 655 FMDRTKEMGEFPKGQVSFMMYIVQPMVEAISALL-PSMTFAVNLCVDNKEYWR 706
>UniRef50_Q4SI77 Cluster: Chromosome 5 SCAF14581, whole genome
shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 5
SCAF14581, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 750
Score = 83.4 bits (197), Expect = 3e-15
Identities = 45/139 (32%), Positives = 75/139 (53%)
Frame = +2
Query: 50 DIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTD 229
+ VNL E ++ R +VI+ +L+TD+ KH LA+ + V G + N D
Sbjct: 502 NFLVNLDHVEFKR-FRFLVIEAILATDLKKHFDFLAEFNSKVNDVNSPG---IDWTNEND 557
Query: 230 RIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATI 409
R+ V + + AD++ P K L+ +W ++ EF++QGD E + G+ +SP DR + +
Sbjct: 558 RLLVCQVCIKLADINGPAKIRDLHLQWTEGIVNEFYEQGDEEAKLGLPVSPFMDRSSPQL 617
Query: 410 EKSQVGFIDYIVHPLWETW 466
K Q FI +IV PL ++
Sbjct: 618 AKLQESFITHIVGPLCNSY 636
>UniRef50_O96077 Cluster: EFPDE3; n=1; Ephydatia fluviatilis|Rep:
EFPDE3 - Ephydatia fluviatilis
Length = 1054
Score = 83.4 bits (197), Expect = 3e-15
Identities = 44/140 (31%), Positives = 79/140 (56%), Gaps = 1/140 (0%)
Frame = +2
Query: 56 FVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRI 235
F+ EE + + R ++++ VL+TD+ H LL+D + V+ ++ G + + DR+
Sbjct: 727 FLGDMEEAELKRFRFLLVEAVLATDLKMHFDLLSDFRAKVDPEEDGG---IDWSSEVDRL 783
Query: 236 QVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDR-HNATIE 412
V++ ++ AD+S PTK L++ W L+ EEF+QQG++E G+ + DR H +
Sbjct: 784 TVMKMIMKMADISTPTKSYELHRAWTKLITEEFYQQGEQEIVLGLPPTIFLDRKHPEKLP 843
Query: 413 KSQVGFIDYIVHPLWETWAD 472
Q+ FI +V PL+ A+
Sbjct: 844 AVQLSFIQNLVSPLFHACAE 863
>UniRef50_A2E8N2 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1103
Score = 83.4 bits (197), Expect = 3e-15
Identities = 48/169 (28%), Positives = 93/169 (55%), Gaps = 1/169 (0%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VA ++ + +IF + EE+ + + ++I M+ +TDM H S++ + +++
Sbjct: 899 VAIGIISKEKTNIFTGIPEEDIPR-IWTIIIHMIKATDMKLHFSIVQKAQELLD------ 951
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SG +++ R+ ++ L+ +D+SN ++P +W +L EEFF+QGD E++ G+ +
Sbjct: 952 SGKFDMNDPACRLLSMQLLLKVSDISNVSRPFDFANKWCDILNEEFFRQGDNEKKLGLGL 1011
Query: 377 -SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEEN 520
SP+ DR NA K Q+GF ++I PL+ + P D++ +N
Sbjct: 1012 SSPLNDRENADKPKGQIGFYNFICLPLYNV-VKRIFPALSVNADSVSDN 1059
>UniRef50_UPI0000660DD6 Cluster: Homolog of Homo sapiens
"Phosphodiesterase PDE9A5; n=1; Takifugu rubripes|Rep:
Homolog of Homo sapiens "Phosphodiesterase PDE9A5 -
Takifugu rubripes
Length = 305
Score = 83.0 bits (196), Expect = 4e-15
Identities = 42/119 (35%), Positives = 69/119 (57%)
Frame = +2
Query: 107 IDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTK 286
I ++L+TDM++H +L K +KV G D+ T VL + C D+SN +
Sbjct: 3 ITLILATDMARHGEILDSFK-----QKVDGFDFADEDHMTCLKMVL---IKCCDISNEVR 54
Query: 287 PLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATIEKSQVGFIDYIVHPLWET 463
P+ + + WV L+EE+F Q DRE+ G+ ++P DR T +Q+GFI +++ P++ET
Sbjct: 55 PMEVAEPWVDCLLEEYFMQSDREKTEGLPVAPFMDREKVTKPTAQIGFIKFVLIPMFET 113
>UniRef50_UPI00015B464B Cluster: PREDICTED: similar to
ENSANGP00000010843; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000010843 - Nasonia
vitripennis
Length = 801
Score = 82.6 bits (195), Expect = 5e-15
Identities = 50/162 (30%), Positives = 84/162 (51%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAF +L+ C+I +L E R +R+ +I +L+TDM++H +LA V +
Sbjct: 623 VAFHILEAPECNILASLQPETYR-IVREGIIRCILATDMARHNEILAQFTDAVPDFDYSS 681
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ L + L+ AD+SN +P+ + + W+ L++EFF+Q D E+ G+ +
Sbjct: 682 KVHINLLSMV--------LIKVADISNEARPMDVAEPWLDSLLQEFFKQSDAEKLEGLPV 733
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDIL 502
+P DR T SQ FI ++ PL+E +L P+ D L
Sbjct: 734 TPFMDRDKVTKPSSQCSFIGLVLLPLFEILGEL-FPELTDAL 774
>UniRef50_Q57V52 Cluster: 3', 5'-cyclic nucleotide
phosphodiesterase, putative; n=3; Trypanosoma|Rep: 3',
5'-cyclic nucleotide phosphodiesterase, putative -
Trypanosoma brucei
Length = 676
Score = 82.6 bits (195), Expect = 5e-15
Identities = 52/170 (30%), Positives = 89/170 (52%), Gaps = 3/170 (1%)
Frame = +2
Query: 23 FKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKT-MVETKKVAGS 199
F+LL++ ++ L++E+ R T+R+ +++MVL+TDMS H ++L ++ +VE +
Sbjct: 511 FQLLKHPSYNVLAPLNDEQFR-TVRETMVEMVLATDMSNHGTILKRFQSRLVEASDWSA- 568
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS 379
N D + L + ADLSN +P +Y W + + +EF++QGD E + IS
Sbjct: 569 ------NKQDVLVALSMSIKTADLSNCIRPYYIYSEWSSYIAQEFYKQGDEEERSNLSIS 622
Query: 380 PMCDRHNA--TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENR 523
P +R + + Q FI Y+V P+ E + P + L E NR
Sbjct: 623 PFMNRKTSDKDFPEGQKSFITYVVAPMMEA-VVMFLPHLRFTLQLCENNR 671
>UniRef50_Q01CI7 Cluster: Cyclic GMP phosphodiesterase; n=1;
Ostreococcus tauri|Rep: Cyclic GMP phosphodiesterase -
Ostreococcus tauri
Length = 526
Score = 82.2 bits (194), Expect = 7e-15
Identities = 51/158 (32%), Positives = 80/158 (50%), Gaps = 4/158 (2%)
Frame = +2
Query: 74 EEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQV-LEN 250
++ R + K++ MVL TDM H L+ + VE + +G+L + + L
Sbjct: 355 DDDRVLVLKLLQKMVLCTDMEVHADLVKKVIEAVEREFDKEAGLLKPVKEWGEVWIPLAF 414
Query: 251 LVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNAT---IEKSQ 421
+HCAD+SNP +P L W ++EEFF+QGD +R M + DR A+ + SQ
Sbjct: 415 ALHCADISNPARPYDLALYWANAIVEEFFKQGDLQRGFQMSVPGFMDRRLASPAGTQSSQ 474
Query: 422 VGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQ 535
+GFI IV P E + A ++L +E N + Y+
Sbjct: 475 LGFIKVIVKPSLELLDSYMPQAAAELLSHIETNIERYE 512
>UniRef50_A3FQ29 Cluster: CGMP phosphodiesterase A4; n=2;
Cryptosporidium|Rep: CGMP phosphodiesterase A4 -
Cryptosporidium parvum Iowa II
Length = 997
Score = 82.2 bits (194), Expect = 7e-15
Identities = 46/182 (25%), Positives = 92/182 (50%), Gaps = 3/182 (1%)
Frame = +2
Query: 5 FGTRVAFKLLQ--NDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVE 178
F + F+++ G F+ + E + R++VI+++L TDM +H ++ + +
Sbjct: 797 FHASLTFRIIYYYGGGAADFLQSWDAELHKEFRRIVIELILETDMHRHFECVSRFRVRRQ 856
Query: 179 TKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRER 358
G + DR+ + + AD+ + + +W ++EEFF QGD E+
Sbjct: 857 AVDWDPYG-----DAQDRLMLARTCLKAADIGHGALKWNQHYKWCRSVVEEFFLQGDEEK 911
Query: 359 EHGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADL-VHPDAQDILDTLEENRDYYQ 535
+ ISP+CDR + + KSQVGF++++ PL++ + V D + +D + EN + ++
Sbjct: 912 ALSLPISPICDRESTDVPKSQVGFLNFVCLPLFQELCYVDVEGDVRRCIDRILENINNWE 971
Query: 536 SM 541
+
Sbjct: 972 DI 973
>UniRef50_A2FQ29 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=2; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1175
Score = 82.2 bits (194), Expect = 7e-15
Identities = 49/177 (27%), Positives = 89/177 (50%), Gaps = 1/177 (0%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V ++ + C++ +L+ + Q + ++I+++L TDM+KH L +L ++ K+
Sbjct: 982 VCISIMTREDCNLLKSLNISDT-QKMWNLIINLILITDMAKHFEFLQELDKIINEKRDW- 1039
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMD- 373
DR +L+ ++ +D+S + L RW A+L EEFF+QGD E+ GM+
Sbjct: 1040 -------RQNDRQTILQMIIKLSDISTIFRKFELADRWTAVLCEEFFRQGDLEKAAGMEY 1092
Query: 374 ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SP+ DR + KSQ+GF + P A ++ D L + EN ++ +
Sbjct: 1093 TSPLNDREHLDKSKSQIGFYTNVCLPFANKAAQIL-DGLDDALKNVNENLQTWKERV 1148
>UniRef50_Q4RSB8 Cluster: Chromosome 13 SCAF15000, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 13 SCAF15000, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 737
Score = 81.8 bits (193), Expect = 9e-15
Identities = 47/139 (33%), Positives = 72/139 (51%)
Frame = +2
Query: 50 DIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTD 229
+ VNL E ++ R +VI+ +L+TD+ KH LA+ V G + N D
Sbjct: 482 NFLVNLDHVEFKR-FRFLVIEAILATDLKKHFDFLAEFNAKVGDDPSTG---IDWSNEND 537
Query: 230 RIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATI 409
R+ V + + AD++ P K L+ +W ++ EF+QQGD E G+ ISP DR +
Sbjct: 538 RLLVCQMCIKLADVNGPLKCKDLHLQWTEGIVNEFYQQGDEESTLGLPISPFMDRAAPQL 597
Query: 410 EKSQVGFIDYIVHPLWETW 466
K Q FI +IV PL ++
Sbjct: 598 AKLQESFITHIVGPLCNSY 616
>UniRef50_A5JZK2 Cluster: 3',5'-cyclic-nucleotide phosphodiesterase,
putative; n=5; Plasmodium|Rep: 3',5'-cyclic-nucleotide
phosphodiesterase, putative - Plasmodium vivax
Length = 1164
Score = 81.8 bits (193), Expect = 9e-15
Identities = 43/150 (28%), Positives = 86/150 (57%), Gaps = 2/150 (1%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
+ FK+LQ + C++ + E++ R +R +I+++LSTDM H +++ + E +
Sbjct: 948 ITFKILQLNQCNLLKSFSEKDFR-LIRSYIIELILSTDMKYHFEIISKFRIRRENEDFD- 1005
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ N D + +++ ++ AD+S+ + + +W ++ EF+ QGD E ++ M +
Sbjct: 1006 ----YVKNNDDLLVLIKMIIKSADISHGSVKWNEHYKWCQRVLCEFYSQGDEELKNKMPL 1061
Query: 377 SPMCDR--HNATIEKSQVGFIDYIVHPLWE 460
SP+CDR HN + SQ+ F+ ++V PL+E
Sbjct: 1062 SPLCDRTKHNEVCQ-SQITFLKFVVMPLFE 1090
>UniRef50_Q13370 Cluster: cGMP-inhibited 3',5'-cyclic
phosphodiesterase B; n=26; Euteleostomi|Rep:
cGMP-inhibited 3',5'-cyclic phosphodiesterase B - Homo
sapiens (Human)
Length = 1112
Score = 81.8 bits (193), Expect = 9e-15
Identities = 45/133 (33%), Positives = 72/133 (54%)
Frame = +2
Query: 68 HEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLE 247
H E +R R +VI+ +L+TD+ KH LA+ + V +G+ N DR+ V +
Sbjct: 876 HVEFKR--FRFLVIEAILATDLKKHFDFLAEFNA--KANDVNSNGIEW-SNENDRLLVCQ 930
Query: 248 NLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATIEKSQVG 427
+ AD++ P K L+ +W ++ EF++QGD E G+ ISP DR + + K Q
Sbjct: 931 VCIKLADINGPAKVRDLHLKWTEGIVNEFYEQGDEEANLGLPISPFMDRSSPQLAKLQES 990
Query: 428 FIDYIVHPLWETW 466
FI +IV PL ++
Sbjct: 991 FITHIVGPLCNSY 1003
>UniRef50_A7AR41 Cluster: 3'5'-cyclic nucleotide phosphodiesterase,
putative; n=1; Babesia bovis|Rep: 3'5'-cyclic nucleotide
phosphodiesterase, putative - Babesia bovis
Length = 777
Score = 81.4 bits (192), Expect = 1e-14
Identities = 51/175 (29%), Positives = 88/175 (50%), Gaps = 1/175 (0%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A ++L GC++F + + +R +I+ +L+TD +++ ++ K+
Sbjct: 575 ALRVLCTPGCNLFPDCDYDY----VRSQIIEHILATDTVDQFHMISQF--VLSCKR---- 624
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS 379
+ Y RI + L+ AD++ PT WV+ L+ EF+ QG E ++ + IS
Sbjct: 625 DDFTFEEYNSRILTSKMLMKAADVAAPTMQWANSLEWVSRLLGEFYAQGAEEVDYCIPIS 684
Query: 380 PMCDR-HNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+CDR H+ KSQ F+ +V PL+E A L P+ I+D LEEN + + M
Sbjct: 685 ALCDRQHHEQSAKSQAAFLRIVVAPLYEAIASLGSPEIDAIMDQLEENAEKWNEM 739
>UniRef50_A2DNV4 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1023
Score = 81.4 bits (192), Expect = 1e-14
Identities = 50/172 (29%), Positives = 93/172 (54%), Gaps = 5/172 (2%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V ++ N+ ++F E +Q + +M+ ++L TDM H +++ +++
Sbjct: 853 VTIGIMTNEMSNVFA-CFEGQQYSKMWQMLFTLILGTDMFHHYTIIKQFNELLD------ 905
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMD- 373
G L + +R+++++ L+ C D+SN ++P + +W +L EEFF+QGD E+ GM+
Sbjct: 906 KGPLDYSDDQNRLKLMQILLKCGDISNVSRPFKIADKWCDVLCEEFFRQGDLEQAQGMEY 965
Query: 374 ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPD----AQDILDTLEE 517
S + DR + KSQ+GF ++ PL+E A+ P+ Q IL L+E
Sbjct: 966 TSNLNDRAHLDKPKSQIGFYKFVCLPLFEV-AERAIPELGVNKQSILINLKE 1016
>UniRef50_A2EHB3 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=2; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1213
Score = 80.2 bits (189), Expect = 3e-14
Identities = 46/148 (31%), Positives = 81/148 (54%), Gaps = 1/148 (0%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V+ +L D +F N ++E ++ + ID+V++TDMSKH ++ +++ +
Sbjct: 993 VSITILSKDESALFNNFPDDEIA-SVWTLFIDLVMATDMSKHFDIVDEMREYL------A 1045
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
G+ D+ R+ ++ L+ AD+SN + RW +L EEFF+QGD ER GM+
Sbjct: 1046 MGLTWKDHPKGRLLFMKLLIKAADISNCVREFETADRWADVLCEEFFRQGDLERALGMEY 1105
Query: 377 -SPMCDRHNATIEKSQVGFIDYIVHPLW 457
P+ +R + +KSQ+GF + PL+
Sbjct: 1106 DGPLHERQHLNKQKSQLGFYKSVALPLY 1133
>UniRef50_A2F9J4 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1119
Score = 79.8 bits (188), Expect = 4e-14
Identities = 54/173 (31%), Positives = 83/173 (47%), Gaps = 1/173 (0%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A +LL DI + + + I ++L+TDM KHM + D + + TK+
Sbjct: 943 AIRLLAMPEHDILEGIESYADKCHFYEFFIKIILATDMEKHMQYIKDFEEV--TKEFDKR 1000
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS 379
N R+ + + ++ DLSN T+ LMEEFF+QGD E + G++I+
Sbjct: 1001 ------NEKHRLLLAQIVIKAGDLSNTTRAFDTAAAMATNLMEEFFKQGDLESKLGVEIT 1054
Query: 380 PMCDRHNAT-IEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQ 535
PMCDR AT I SQVGF + PL + D + LE+N+ ++
Sbjct: 1055 PMCDRSKATHISCSQVGFYGFCASPLLTALGKFI-TSLADNTEQLEKNKRVWE 1106
>UniRef50_A0EHP5 Cluster: Chromosome undetermined scaffold_97, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_97, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 908
Score = 79.8 bits (188), Expect = 4e-14
Identities = 53/177 (29%), Positives = 92/177 (51%), Gaps = 1/177 (0%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
+AFK++Q + +I NL +EQ Q +R+ ++ +L+TDM KH L++ L+ +
Sbjct: 741 MAFKIMQREKYNILSNL-SQEQFQKVRRFMVSNILATDMKKHFDLVSSLEIKYK------ 793
Query: 197 SGVLLLDNYTDRIQVLENL-VHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMD 373
+G + + N D +VL L VH DL+ PTK + K+W + EF Q + ER G+
Sbjct: 794 NGEMNIVNM-DTKRVLSGLIVHTCDLTQPTKRFEITKKWSIRIQNEFDNQVEEERLLGLP 852
Query: 374 ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
I+ N + K ++ FI I+ PL+ + +++ L LEEN + ++
Sbjct: 853 ITQHLVCQN--LPKQELSFIRNIIQPLYALTSSILNNGLSVALKCLEENEKEWTKLL 907
>UniRef50_O00408 Cluster: cGMP-dependent 3',5'-cyclic
phosphodiesterase; n=47; Eumetazoa|Rep: cGMP-dependent
3',5'-cyclic phosphodiesterase - Homo sapiens (Human)
Length = 941
Score = 78.6 bits (185), Expect = 9e-14
Identities = 48/171 (28%), Positives = 90/171 (52%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A +L GC+IF + ++ ++ L ++ D++L+TD++ H+ + DL+ M E
Sbjct: 734 AIAILNTHGCNIFDHFSRKDYQRML-DLMRDIILATDLAHHLRIFKDLQKMAEV------ 786
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS 379
G + R+ + + C DLS+ TK ++ L+ +EFF QGD E+ G
Sbjct: 787 GYDRNNKQHHRLLLCLLMTSC-DLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPM 845
Query: 380 PMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYY 532
M DR A I + Q+ F+++I P+++ DL P A ++ + + NR+++
Sbjct: 846 EMMDREKAYIPELQISFMEHIAMPIYKLLQDL-FPKAAELYERVASNREHW 895
>UniRef50_Q9VYJ0 Cluster: CG32648-PA; n=3; Coelomata|Rep: CG32648-PA
- Drosophila melanogaster (Fruit fly)
Length = 963
Score = 78.2 bits (184), Expect = 1e-13
Identities = 46/175 (26%), Positives = 88/175 (50%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
+AF+LL++ C+IF N + +R+ +I +L+TDM++H +L + +
Sbjct: 187 IAFRLLEHPECNIFKNF-SRDTFNNIREGIIRCILATDMARHNEILTQFMEITPIFDYSN 245
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ L + L+ AD+SN +P+ + + W+ L++EFF Q E+ G+ +
Sbjct: 246 RAHINL--------LCMILIKVADISNEARPMDVAEPWLDRLLQEFFAQSAAEKSEGLPV 297
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+P D + SQV FI ++ PL+E +LV + I+ + +YY+ +
Sbjct: 298 TPFMDPDKVSKPGSQVRFIGLVLLPLFEALGELVPELTELIIIPVRIALEYYRRL 352
>UniRef50_UPI00015B4531 Cluster: PREDICTED: similar to cyclic GMP
stimulated phosphodiesterase; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to cyclic GMP
stimulated phosphodiesterase - Nasonia vitripennis
Length = 1684
Score = 76.2 bits (179), Expect = 5e-13
Identities = 53/170 (31%), Positives = 87/170 (51%), Gaps = 1/170 (0%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+L +GC+IF NL EE + L ++ + +L+TD++ H +++ E + V G
Sbjct: 517 ILNTEGCNIFENLSSEEYSEAL-DLLRNNILATDLASHF------RSVEEQRDVTKQGYD 569
Query: 209 LLDNYTDRIQVLENL-VHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPM 385
N ++L + + C DL++ TK + K+ + +EFF QGD E+ G M
Sbjct: 570 --KNNPKHQKILHAMFMTCCDLNDQTKNWRVSKQTAEQIYDEFFSQGDLEKSMGTAPIEM 627
Query: 386 CDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQ 535
DR A+I QV FI +V PL+ A L P Q I+ +E NR+ ++
Sbjct: 628 MDRERASIPDLQVQFITNLVLPLFTNLATL-FPSMQPIVHIIERNREIWR 676
>UniRef50_UPI0000E48F4D Cluster: PREDICTED: similar to camp and
camp-inhibited cgmp 3,5-cyclic phosphodiesterase; n=2;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
camp and camp-inhibited cgmp 3,5-cyclic
phosphodiesterase - Strongylocentrotus purpuratus
Length = 1197
Score = 76.2 bits (179), Expect = 5e-13
Identities = 55/160 (34%), Positives = 84/160 (52%), Gaps = 1/160 (0%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+LQNDG +IF +L EE +Q L + +L+TD++ A LK +VE K +
Sbjct: 112 ILQNDGHNIFKHLSSEEYKQVLGD-IRHAILATDLALFFPNKAKLKKIVEEKNFSW---- 166
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMC 388
DN R V + DL+ TKP + ++ V ++ +EF+QQGD E+ G + PM
Sbjct: 167 --DNQEHRQCVKALSMTACDLAANTKPWHIQQQTVKVIFDEFYQQGDEEKAAGRNPIPMM 224
Query: 389 DRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILD 505
DR A + +QV FI I P ++ A LV P A+ + +
Sbjct: 225 DRDRAHELPANQVSFIVGICLPCYDLLAQLV-PSAKPMYE 263
>UniRef50_Q4SV96 Cluster: Chromosome 10 SCAF13771, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 10 SCAF13771, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 816
Score = 64.9 bits (151), Expect(2) = 6e-13
Identities = 35/96 (36%), Positives = 52/96 (54%), Gaps = 2/96 (2%)
Frame = +2
Query: 185 KVAGSGVLLLD--NYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRER 358
+V GV +D N DR+ V + + AD++ P K L+ +W ++ EF+QQGD E
Sbjct: 610 QVGDDGVPGIDWTNENDRLLVCQMCIKLADVNGPLKCKELHLQWTEGIVNEFYQQGDEEA 669
Query: 359 EHGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETW 466
G+ ISP DR + K Q FI +IV PL ++
Sbjct: 670 SLGLPISPFMDRSAPQLAKLQESFITHIVGPLCSSY 705
Score = 31.1 bits (67), Expect(2) = 6e-13
Identities = 15/42 (35%), Positives = 24/42 (57%)
Frame = +2
Query: 50 DIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMV 175
+ VNL E ++ R +VI+ +L+TD+ KH LA+ V
Sbjct: 529 NFLVNLEHVEFKR-FRFLVIEAILATDLKKHFDFLAEFNAKV 569
>UniRef50_Q8I6Y6 Cluster: CGMP-specific phosphodiesterase; n=3;
Dictyostelium discoideum|Rep: CGMP-specific
phosphodiesterase - Dictyostelium discoideum (Slime
mold)
Length = 522
Score = 75.8 bits (178), Expect = 6e-13
Identities = 43/165 (26%), Positives = 83/165 (50%)
Frame = +2
Query: 44 GCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNY 223
G ++ L EE++Q R++ I ++L+TDM H + ++ T DN
Sbjct: 355 GNELLSTLTVEEKKQFFRRVKI-LILATDMENHFTYKKQFDDIIST--------FSWDNS 405
Query: 224 TDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNA 403
R +L + AD+SN + + +W LMEEFF Q D E+ + + ++P +R
Sbjct: 406 EHRDLLLIMFLKSADISNELRSFDISNKWANALMEEFFNQSDLEKLNNLPLTPFMEREKV 465
Query: 404 TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQS 538
+ +QV FI+ + P +++ +L+ P +D + + EN++ + +
Sbjct: 466 VLHLTQVSFIEKFLLPSYQSLQNLL-PSLEDFVQRIIENKEIWSN 509
>UniRef50_Q5CXM2 Cluster: Membrane associated HD superfamily cyclic
nucleotide phosphodiesterase domain containing protein;
n=2; Cryptosporidium|Rep: Membrane associated HD
superfamily cyclic nucleotide phosphodiesterase domain
containing protein - Cryptosporidium parvum Iowa II
Length = 1967
Score = 75.8 bits (178), Expect = 6e-13
Identities = 34/103 (33%), Positives = 65/103 (63%), Gaps = 1/103 (0%)
Frame = +2
Query: 227 DRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCD-RHNA 403
D+ ++E L+H AD+SNP P P+ +W +L++EEF Q E + G+ I+P D + +
Sbjct: 1733 DKEFLIETLLHAADISNPITPFPICAKWSSLIVEEFNYQSKLESQFGLPITPFMDLKDDI 1792
Query: 404 TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYY 532
T ++Q+GF+++I+ P W+ + ++ P + +L E+NR+ +
Sbjct: 1793 TKIEAQIGFLEFIIIPQWKLLSRII-PKSIILLKQAEKNRELW 1834
Score = 34.7 bits (76), Expect = 1.4
Identities = 21/54 (38%), Positives = 32/54 (59%), Gaps = 1/54 (1%)
Frame = +2
Query: 23 FKLLQN-DGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVET 181
F LL DI N ++ E++ R++ I VLSTDMS H +LL++L+ + T
Sbjct: 1630 FSLLDKCQDLDIRKNFNDFEKKN-FRRIFIRSVLSTDMSYHNTLLSNLEEFIST 1682
>UniRef50_O96076 Cluster: EFPDE2; n=1; Ephydatia fluviatilis|Rep:
EFPDE2 - Ephydatia fluviatilis
Length = 819
Score = 75.8 bits (178), Expect = 6e-13
Identities = 51/168 (30%), Positives = 87/168 (51%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+L + GC+IF NL + + R T++ ++ D +L TD++ H LK + K++A G
Sbjct: 645 ILNSPGCNIFENLSDSDYRTTIQ-LIQDNILDTDIASH------LKKLKHIKQMANDGYE 697
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMC 388
+ R+ + C DL+ K K L+ +EFF QGD E+ G+ S M
Sbjct: 698 RSNPEHHRLMCSLIMTSC-DLTASCKTWESNKAISDLIYQEFFSQGDLEKALGVTPSEMM 756
Query: 389 DRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYY 532
DR A I + Q+ F+D I P+++ + L+ P++ TL +NR+ +
Sbjct: 757 DRDRAFIPEQQLQFLDNIAGPVYQLLSRLL-PESAAAYHTLLDNREQW 803
>UniRef50_UPI000065CC62 Cluster: cGMP-inhibited 3',5'-cyclic
phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited
phosphodiesterase A) (CGI-PDE A).; n=1; Takifugu
rubripes|Rep: cGMP-inhibited 3',5'-cyclic
phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited
phosphodiesterase A) (CGI-PDE A). - Takifugu rubripes
Length = 706
Score = 64.1 bits (149), Expect(2) = 8e-13
Identities = 31/83 (37%), Positives = 46/83 (55%)
Frame = +2
Query: 218 NYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRH 397
N DR+ V + + AD++ P K L+ +W ++ EF+QQGD E G+ ISP DR
Sbjct: 529 NENDRLLVCQMCIKLADVNGPLKCKDLHLQWTEGIVNEFYQQGDEESSMGLPISPFMDRA 588
Query: 398 NATIEKSQVGFIDYIVHPLWETW 466
+ K Q FI +IV PL ++
Sbjct: 589 APQLAKLQESFITHIVGPLCNSY 611
Score = 31.5 bits (68), Expect(2) = 8e-13
Identities = 16/45 (35%), Positives = 25/45 (55%)
Frame = +2
Query: 50 DIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETK 184
+ VNL E ++ R +VI+ +L+TD+ KH LA+ V K
Sbjct: 445 NFLVNLDHVEFKR-FRFLVIEAILATDLKKHFDFLAEFNAKVMIK 488
>UniRef50_UPI000150A9A4 Cluster: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein; n=1; Tetrahymena
thermophila SB210|Rep: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein - Tetrahymena
thermophila SB210
Length = 929
Score = 73.3 bits (172), Expect = 3e-12
Identities = 50/175 (28%), Positives = 81/175 (46%), Gaps = 2/175 (1%)
Frame = +2
Query: 23 FKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSG 202
FK++Q +IF L E+ + +RK I +LSTDM KH L + + K G+
Sbjct: 737 FKIIQKH--NIFEQLSNEDVKN-IRKYCISNILSTDMKKHQELTKQFEIKLTYLKQEGTD 793
Query: 203 VLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISP 382
L+ + D+ + LVH ADL+ PTK L K W + +EF Q E G+ ++P
Sbjct: 794 --LIKSEADKKLMCGFLVHVADLTGPTKCFELAKEWSMRICKEFTLQVQEEEHLGLPVTP 851
Query: 383 MCD--RHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
I K + F IV PL+ ++ P+ + ++ E N ++ +
Sbjct: 852 YLVGLESMEIISKQEGNFAKIIVLPLYSVLSEFAGPEFKQMVKNCENNISQWEKI 906
>UniRef50_Q14432 Cluster: cGMP-inhibited 3',5'-cyclic
phosphodiesterase A; n=27; Euteleostomi|Rep:
cGMP-inhibited 3',5'-cyclic phosphodiesterase A - Homo
sapiens (Human)
Length = 1141
Score = 73.3 bits (172), Expect = 3e-12
Identities = 43/139 (30%), Positives = 69/139 (49%)
Frame = +2
Query: 50 DIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTD 229
+ +NL E + R +VI+ +L+TD+ KH +A KV + N D
Sbjct: 884 NFLINLDHVEFKH-FRFLVIEAILATDLKKHFDFVAKFNG-----KVNDDVGIDWTNEND 937
Query: 230 RIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATI 409
R+ V + + AD++ P K L+ +W ++ EF++QGD E G+ ISP DR +
Sbjct: 938 RLLVCQMCIKLADINGPAKCKELHLQWTDGIVNEFYEQGDEEASLGLPISPFMDRSAPQL 997
Query: 410 EKSQVGFIDYIVHPLWETW 466
Q FI +IV PL ++
Sbjct: 998 ANLQESFISHIVGPLCNSY 1016
>UniRef50_Q17L35 Cluster: Cgmp-dependent 3,5-cyclic
phosphodiesterase; n=2; Culicidae|Rep: Cgmp-dependent
3,5-cyclic phosphodiesterase - Aedes aegypti
(Yellowfever mosquito)
Length = 502
Score = 72.9 bits (171), Expect = 4e-12
Identities = 48/171 (28%), Positives = 83/171 (48%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A +L + I +L EE ++ + + D++L+TD++ H ++ LK + GS
Sbjct: 319 AICILNDSSSKILDSLSTEEFKECI-DFLRDLILATDLANHFRIMPHLKRLRPENLGEGS 377
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS 379
LL L ++ C DLS+ K + L+ EFF +GD E++ G+ +
Sbjct: 378 NQRLL---------LSLMITCCDLSDQVKSWKTVQHVAHLVYAEFFAEGDLEKQMGLRPN 428
Query: 380 PMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYY 532
M DR A I Q+ F+ +V P +E A + P+ Q L+T++ NR +
Sbjct: 429 AMMDRKKACIPVLQIEFLTMVVRPTFEILAQ-IFPETQHFLETIDCNRQQW 478
>UniRef50_UPI00006CB6E9 Cluster: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein; n=1; Tetrahymena
thermophila SB210|Rep: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein - Tetrahymena
thermophila SB210
Length = 699
Score = 72.1 bits (169), Expect = 8e-12
Identities = 53/181 (29%), Positives = 86/181 (47%), Gaps = 13/181 (7%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETK---- 184
V FK+L+ +I L EQ Q +RK+VI +L+TD+ +H LL D + K
Sbjct: 383 VTFKILRKKEANILTQL-PLEQVQQIRKIVISNILATDIKQHFDLLKDFELRFGNKGLKL 441
Query: 185 ----KVAGSGVLLLDNYTDR-IQVLEN-LVHCADLSNPTKPLPLYKRWVALLMEEFFQQG 346
++ + Y+D + ++ N ++H AD + L K+W L+ +EF Q
Sbjct: 442 KNDFQINEQECQSVTTYSDNDLNLITNMMIHAADFHGNAQEFELSKKWSLLVNQEFQAQY 501
Query: 347 DREREHGMDISPM---CDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEE 517
E E + +P D+ + + KS++GFI+ IV PLWE + D Q + L
Sbjct: 502 KEEAEKNIPQTPYLKDLDKRD-ILAKSEIGFINAIVKPLWELLNKFLGDDLQISTNNLSN 560
Query: 518 N 520
N
Sbjct: 561 N 561
>UniRef50_Q4RR95 Cluster: Chromosome 14 SCAF15003, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 14 SCAF15003, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 456
Score = 72.1 bits (169), Expect = 8e-12
Identities = 34/90 (37%), Positives = 52/90 (57%), Gaps = 2/90 (2%)
Frame = +2
Query: 260 CADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATIEKSQVGFIDY 439
CAD+ NP + L ++W + EEFF+QGD ER+ ++ISP+CD Q GFI Y
Sbjct: 361 CADVCNPCRVWALSRQWSERVCEEFFRQGDLERKFDLEISPLCDSRRLR-PAIQTGFISY 419
Query: 440 IVHPLWETWADLVHPD--AQDILDTLEENR 523
IV PL++ W P ++ ++ L +N+
Sbjct: 420 IVEPLFDEWHRFTEPSPLSRTMMGHLHQNK 449
>UniRef50_A6R1R4 Cluster: Predicted protein; n=1; Ajellomyces
capsulatus NAm1|Rep: Predicted protein - Ajellomyces
capsulatus NAm1
Length = 839
Score = 72.1 bits (169), Expect = 8e-12
Identities = 50/157 (31%), Positives = 77/157 (49%), Gaps = 6/157 (3%)
Frame = +2
Query: 92 LRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNY--TDRIQVLENLVHCA 265
LRK++I +L+TDM H + L + E S DN T+R + L+ CA
Sbjct: 353 LRKLMISSILATDMGVHFKFMESLGKLREKYHETHSTDRWTDNEIETNRALLCGLLMKCA 412
Query: 266 DLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS----PMCDRHNATIEKSQVGFI 433
D+SN + + KRW +L EEF QQG+ E+ GM+ + P + + KSQ+ FI
Sbjct: 413 DISNVARTWDIAKRWTNVLQEEFAQQGNMEKTIGMETALFGGPPELGNVPKLAKSQINFI 472
Query: 434 DYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
PL+E A L+ PD + N+ ++ +I
Sbjct: 473 KLFALPLFENLAYLL-PDMAFTTVEIRRNKSIWREII 508
>UniRef50_Q3SBD3 Cluster: Sperm phosphodiesterase 5; n=1;
Strongylocentrotus purpuratus|Rep: Sperm
phosphodiesterase 5 - Strongylocentrotus purpuratus
(Purple sea urchin)
Length = 949
Score = 71.3 bits (167), Expect = 1e-11
Identities = 54/173 (31%), Positives = 90/173 (52%), Gaps = 2/173 (1%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+L ++G +IF + ++ R+ +R M+ +LSTD++ + AD +VE G
Sbjct: 697 ILNSEGNNIFEFMSPDDYREAIR-MLESAILSTDLAIYFKKRADFFKLVE------KGEH 749
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREH-GMDISPM 385
DN + + L+ D+S KP + ++ L+ EFFQQGD ERE + M
Sbjct: 750 TWDNEEKKGLLRGMLMTACDVSAIAKPWLVQQKVAELVFSEFFQQGDLEREKLKEEPMAM 809
Query: 386 CDRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
DR + K QVGFID I P+++ +A+L PD + + + NRD +Q++
Sbjct: 810 MDRKKKDELPKMQVGFIDGICMPVYKMFAEL-WPDLKPLESGTQLNRDNWQAL 861
>UniRef50_Q6CHK1 Cluster: Similar to tr|Q8NJP9 Candida albicans High
affinity cAMP phosphodiesterase; n=1; Yarrowia
lipolytica|Rep: Similar to tr|Q8NJP9 Candida albicans
High affinity cAMP phosphodiesterase - Yarrowia
lipolytica (Candida lipolytica)
Length = 626
Score = 71.3 bits (167), Expect = 1e-11
Identities = 45/160 (28%), Positives = 86/160 (53%), Gaps = 5/160 (3%)
Frame = +2
Query: 80 QRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLD----NYTDRIQVLE 247
Q L+K++++ VL+TDM++H + + + + G G + + DR V
Sbjct: 468 QEPHLKKLIVESVLATDMAQHFNYVDRWNELSARCRSKGKGRCNEERGNLSPADRQLVGS 527
Query: 248 NLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMD-ISPMCDRHNATIEKSQV 424
++ CAD+SN T+ L L ++W +L EF + D E + + + P C + NA + +SQV
Sbjct: 528 MIMKCADVSNVTRRLDLAEKWGRVLQCEFSEVKDVETDCNVQTLPPNCGK-NANLAQSQV 586
Query: 425 GFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
F++ +PL++ ++D P+ TL+EN+ ++S +
Sbjct: 587 SFLNIFAYPLFQQFSD-AFPEFGYAFKTLQENKAVWESRL 625
>UniRef50_Q1JT10 Cluster: Phosphodiesterase, putative; n=2;
Eukaryota|Rep: Phosphodiesterase, putative - Toxoplasma
gondii RH
Length = 2092
Score = 70.9 bits (166), Expect = 2e-11
Identities = 45/149 (30%), Positives = 75/149 (50%), Gaps = 1/149 (0%)
Frame = +2
Query: 92 LRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADL 271
LRK+VI + STDM +K + K L+ DR ++ L+HCAD+
Sbjct: 1886 LRKIVIQAIFSTDMELFRQHHDAMKRRAQMKTNDREE---LEGEDDRNLLVTCLIHCADI 1942
Query: 272 SNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCD-RHNATIEKSQVGFIDYIVH 448
NP +W +L+ +EF Q D ER +G+ +S D R +SQ+GF+ ++V
Sbjct: 1943 CNPVMSEGRNVQWASLVTQEFNAQVDLERRYGLPVSVFMDARTELQRTQSQIGFLSFVVL 2002
Query: 449 PLWETWADLVHPDAQDILDTLEENRDYYQ 535
+ ADL+ P+ +++ E+N + +Q
Sbjct: 2003 DQFRALADLI-PEVSELVVQGEKNLEMWQ 2030
>UniRef50_A0BZW8 Cluster: Chromosome undetermined scaffold_14, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_14,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 454
Score = 70.5 bits (165), Expect = 2e-11
Identities = 54/194 (27%), Positives = 91/194 (46%), Gaps = 20/194 (10%)
Frame = +2
Query: 23 FKLLQ-NDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
F ++Q N D F + +E+R ++++I +L+TDMSKH LLA + VE+ K
Sbjct: 259 FNIIQLNRQHDFFQYMTNDEERNLAKRLIITSILATDMSKHNKLLAKFQKRVESTKQFEQ 318
Query: 200 GVL--LLD-------NYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGD- 349
G L+D DRI +L +VH D+SNPT Y W LL +EF Q
Sbjct: 319 GEKNELIDMQRFSNERLEDRIFILNIMVHACDISNPTMKFNNYMNWSYLLTQEFNDQVQH 378
Query: 350 --------REREHGMDISP-MCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDIL 502
+E + G+D++ + + Q+ F V PLW ++ +P+ + +
Sbjct: 379 FNNPLQTIKEAKVGVDVTGFLVYKDKPAYYGGQIFFSKTFVFPLWFQIGEM-YPELKYLS 437
Query: 503 DTLEENRDYYQSMI 544
+ + +N + Q +
Sbjct: 438 EEINKNLEILQQKL 451
>UniRef50_A0D3N1 Cluster: Chromosome undetermined scaffold_36, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_36,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 429
Score = 70.1 bits (164), Expect = 3e-11
Identities = 47/176 (26%), Positives = 86/176 (48%), Gaps = 12/176 (6%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMV-------ETKK 187
L QN + F+N Q+Q +++++ +L+TDM +H ++ + K V E++
Sbjct: 243 LAQNQQLN-FLNYLPNAQQQEFKRILVSSILATDMGQHFNIFSCFKDRVNATIELRESQD 301
Query: 188 VAGSGVLLL----DNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRE 355
+ + +N+ DR +L LVH D+SNP Y +W LL +EF Q +E
Sbjct: 302 ITDPLIRYRGFNKENFDDRKFILNVLVHACDISNPCLEWDAYMKWSFLLAQEFQDQTIKE 361
Query: 356 REHGMDISPMCD-RHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEEN 520
G++++ M + T Q F++ V P W+T A L +P ++ + ++ N
Sbjct: 362 AAKGLEVTAMLQYKDKLTFFNGQTFFLNTFVLPQWQTIATL-YPSLIELPNEVKRN 416
>UniRef50_Q5BYM4 Cluster: SJCHGC06481 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC06481 protein - Schistosoma
japonicum (Blood fluke)
Length = 178
Score = 69.7 bits (163), Expect = 4e-11
Identities = 35/108 (32%), Positives = 57/108 (52%)
Frame = +2
Query: 218 NYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRH 397
N + V+ ++ +D+SN +PL + W+ L+ EFF Q D E+ G+ ++P DRH
Sbjct: 34 NKAQKDLVMVIILKISDISNEARPLNVAGPWINRLLAEFFHQSDYEKLVGLPVAPFMDRH 93
Query: 398 NATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
T SQ GFI +++ PL+E+ A L+ I+ E YY +
Sbjct: 94 KVTKSASQCGFIRFVILPLFESLAKLLPEVKPIIVQPALEQLAYYTEL 141
>UniRef50_UPI00006CF33D Cluster: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein; n=1; Tetrahymena
thermophila SB210|Rep: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein - Tetrahymena
thermophila SB210
Length = 354
Score = 68.1 bits (159), Expect = 1e-10
Identities = 38/163 (23%), Positives = 83/163 (50%), Gaps = 3/163 (1%)
Frame = +2
Query: 41 DGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDN 220
D C +F ++ ++Q ++K + +L+TDMSKH ++ + K + + + + + +
Sbjct: 178 DQCGLFDSI-PQDQLVIMKKYIQHNILATDMSKHNQIMNEFKENLPS--LLKEDLAITEQ 234
Query: 221 YTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPM---CD 391
+I + LVH AD+ PT+ + K W + +EF Q + E+++ + ++P D
Sbjct: 235 --QKINLCGALVHAADIGAPTRDFSISKEWSLRIAKEFTAQLELEQQNNLPVTPFYKDLD 292
Query: 392 RHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEEN 520
++ T+ +++GFI++ + P W Q + +E+N
Sbjct: 293 KY-LTLATNEIGFINFFIKPFWVQIEQFGQGKLQQVSKNIEQN 334
>UniRef50_Q3KVL8 Cluster: High-affinity phosphodiesterase; n=4;
Eukaryota|Rep: High-affinity phosphodiesterase -
Cryptococcus neoformans var. neoformans
Length = 555
Score = 68.1 bits (159), Expect = 1e-10
Identities = 43/164 (26%), Positives = 84/164 (51%), Gaps = 17/164 (10%)
Frame = +2
Query: 83 RQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHC 262
+++ R+++ +L+TDMS H + + LK + K +G + +RI + + L+ C
Sbjct: 394 QKSFRQVLYSSILATDMSLHFAWVQRLKEFDDRLKSGEAGAV----EDERILICQALIKC 449
Query: 263 ADLSNP-----------------TKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCD 391
AD+SNP ++P+ + + W ++L+EE+ +Q E++ + +S +
Sbjct: 450 ADISNPVSLIESTVRLSFDTHLQSRPIDVSQHWSSVLLEEWAKQASLEQDLSLPVSVVAS 509
Query: 392 RHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENR 523
A K Q+GFID PL++ +D + P+ Q D+ EN+
Sbjct: 510 ADAALQAKGQIGFIDLFTKPLFQAVSDAL-PELQPYADSCMENQ 552
>UniRef50_A1D4A4 Cluster: High affinity cAMP phosphodiesterase,
putative; n=8; Trichocomaceae|Rep: High affinity cAMP
phosphodiesterase, putative - Neosartorya fischeri
(strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus
fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181))
Length = 1009
Score = 68.1 bits (159), Expect = 1e-10
Identities = 46/154 (29%), Positives = 80/154 (51%), Gaps = 10/154 (6%)
Frame = +2
Query: 92 LRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDR-IQVLENLV---- 256
LRK++I +L+TDM H + L ++ E G V D + + I++ + LV
Sbjct: 475 LRKLLISSILATDMGVHQKFMERLGSLQEKFYANGKSV---DGWKPQDIEIYKTLVCGLL 531
Query: 257 -HCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS----PMCDRHNATIEKSQ 421
CAD+SN +P + ++W +L EEF QG+ ERE GM+ + P + + Q
Sbjct: 532 IKCADISNVARPWDIAEKWTKILQEEFANQGEMEREVGMETALFGGPPELGNVYKLATGQ 591
Query: 422 VGFIDYIVHPLWETWADLVHPDAQDILDTLEENR 523
+GF+ PL+E +DL+ P+ + ++ + N+
Sbjct: 592 IGFMSIFALPLFEGVSDLL-PELRFTVEHIRTNQ 624
>UniRef50_A4VDP2 Cluster: Cyclic nucleotide phosphodiesterase; n=1;
Tetrahymena thermophila SB210|Rep: Cyclic nucleotide
phosphodiesterase - Tetrahymena thermophila SB210
Length = 1074
Score = 67.7 bits (158), Expect = 2e-10
Identities = 50/171 (29%), Positives = 84/171 (49%), Gaps = 5/171 (2%)
Frame = +2
Query: 23 FKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKT--MVETKKVAG 196
FK+L+ +IF NL ++ +Q +R+ VI+ +L+TDMSKH L D + + E K
Sbjct: 863 FKILRQSNANIFKNLTIQKVQQ-IRRYVINNILATDMSKHFDYLKDFQNDFLQEVHKKES 921
Query: 197 SGVLLLDNYTDRIQVLE-NLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGM- 370
+ I +L ++H +D + + L K+W + +EF QQ E + G+
Sbjct: 922 N-----QFEEKEINLLTGTIIHTSDFHHTAQKFELSKQWSVKVNKEFSQQYIEEGKQGVQ 976
Query: 371 DISPMCDRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEEN 520
S + D + K++ GFI IV PLWET ++ + + LE +
Sbjct: 977 QTSYLKDLDKMHVLAKNEAGFIKMIVKPLWETMNKFLNDQLIEPVSNLENS 1027
>UniRef50_A2GFY4 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein
- Trichomonas vaginalis G3
Length = 457
Score = 66.9 bits (156), Expect = 3e-10
Identities = 41/129 (31%), Positives = 67/129 (51%), Gaps = 1/129 (0%)
Frame = +2
Query: 59 VNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQ 238
+ +E R+ K V +++L+TDMSKH + V +AGS D +R+
Sbjct: 302 IQTFNDETRRIYFKFVSNIILATDMSKHQDYI------VSFNNIAGS---YKDTEDERLL 352
Query: 239 VLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNAT-IEK 415
+ ++ ADLSN +P A L EE++ QGD + + G++I+ DR+N T + +
Sbjct: 353 ACQAIMKLADLSNTCRPFGEAATMSAQLQEEWYTQGDEQLKRGLEITKGFDRNNKTPLPQ 412
Query: 416 SQVGFIDYI 442
QVGF Y+
Sbjct: 413 GQVGFYKYV 421
>UniRef50_O76074 Cluster: cGMP-specific 3',5'-cyclic
phosphodiesterase; n=47; Euteleostomi|Rep: cGMP-specific
3',5'-cyclic phosphodiesterase - Homo sapiens (Human)
Length = 875
Score = 66.9 bits (156), Expect = 3e-10
Identities = 52/173 (30%), Positives = 85/173 (49%), Gaps = 2/173 (1%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+L + G I L EE + TL K++ +L+TD++ ++ + ++ +
Sbjct: 692 ILNSPGNQILSGLSIEEYKTTL-KIIKQAILATDLALYIKRRGEFFELIRKNQFN----- 745
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRER-EHGMDISPM 385
L++ + L L+ DLS TKP P+ +R L+ EFF QGDRER E ++ + +
Sbjct: 746 -LEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFFDQGDRERKELNIEPTDL 804
Query: 386 CDRHNAT-IEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+R I QVGFID I L+E V D +LD +NR +Q++
Sbjct: 805 MNREKKNKIPSMQVGFIDAICLQLYEALTH-VSEDCFPLLDGCRKNRQKWQAL 856
>UniRef50_Q29FT2 Cluster: GA17041-PA; n=1; Drosophila
pseudoobscura|Rep: GA17041-PA - Drosophila pseudoobscura
(Fruit fly)
Length = 815
Score = 66.5 bits (155), Expect = 4e-10
Identities = 39/151 (25%), Positives = 75/151 (49%)
Frame = +2
Query: 89 TLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCAD 268
T+R+ +I +L+TDM++H +L + + + L + L+ AD
Sbjct: 24 TIREGIIRCILATDMARHNEILTQFMEITPIFDYSNRAHINL--------LCMILIKVAD 75
Query: 269 LSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATIEKSQVGFIDYIVH 448
+SN +P+ + + W+ L++EFF Q E+ G+ ++P D + SQV FI ++
Sbjct: 76 ISNEARPMDVAEPWLDRLLQEFFAQSAAEKSEGLPVTPFMDPDKVSKPGSQVRFIGLVLL 135
Query: 449 PLWETWADLVHPDAQDILDTLEENRDYYQSM 541
PL+E +LV + I+ + +YY+ +
Sbjct: 136 PLFEALGELVPELTELIIIPVRIALEYYRRL 166
>UniRef50_Q4KL87 Cluster: MGC116558 protein; n=2; Xenopus|Rep:
MGC116558 protein - Xenopus laevis (African clawed frog)
Length = 342
Score = 66.1 bits (154), Expect = 5e-10
Identities = 37/148 (25%), Positives = 74/148 (50%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VA+++L ++ + + +Q +++ +++++L+TDM+ H +L L+ +
Sbjct: 167 VAWRILSQKQSNLLLGA-DPKQVPHIQQEIMELILATDMAHHGEILQTLQNIENFN---- 221
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
N + + L+ D+SN +P + W LMEE+F Q DRE++ G+ +
Sbjct: 222 -----FSNREHVTALKKGLIKICDISNEARPAEQAEIWADALMEEYFLQSDREKDEGLPV 276
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWE 460
+P DR +Q FI +++ PL E
Sbjct: 277 TPYMDRDKVKKADAQSSFISFLLIPLCE 304
>UniRef50_Q53I59 Cluster: Cyclic nucleotide specific
phosphodiesterase; n=3; Trypanosoma cruzi|Rep: Cyclic
nucleotide specific phosphodiesterase - Trypanosoma
cruzi
Length = 924
Score = 65.7 bits (153), Expect = 7e-10
Identities = 47/174 (27%), Positives = 86/174 (49%)
Frame = +2
Query: 11 TRVAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKV 190
T AF+LL D F + + + +V ++ TDMS H +A K+
Sbjct: 443 TVTAFELLNVTEFD-FTSSMDNASFLEFKNIVSHLIGHTDMSLHSETIAK-----HGAKL 496
Query: 191 AGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGM 370
+ G DR++ L L+H AD+ ++ + + ++W+ +L +EF Q + ER G+
Sbjct: 497 SAGGFDCTCK-EDRLEALSLLLHAADIGASSRGVAIARKWLVIL-QEFADQAEDERRRGL 554
Query: 371 DISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYY 532
++P D +++EKSQ+ F+D+ V P ++ L P ++ L L + R+ Y
Sbjct: 555 PVTPGFDT-PSSVEKSQIPFLDFFVIPTFDLLHQL-FPSIEEPLHNLRKLRELY 606
>UniRef50_A7SW30 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 600
Score = 65.3 bits (152), Expect = 9e-10
Identities = 46/163 (28%), Positives = 83/163 (50%), Gaps = 1/163 (0%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+L+++G ++F L E R+ L +++ + +++TD+ +L+T+ E K
Sbjct: 446 ILESEGQNVFGQLDAESYRRVL-ELIQEAIIATDLMLFFGNKKELETLQENKAFRWEE-- 502
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMC 388
+ + I+ L L+ DL KP + V + EEF+ QGD ER+ G+D PM
Sbjct: 503 --EKHRSLIRCL--LMTACDLCTSAKPWDIQVVAVNKVFEEFYIQGDEERKMGLDPLPMM 558
Query: 389 DR-HNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE 514
DR + + ++QVGF+ IV P + D V P+ ++ +E
Sbjct: 559 DRSKHDDLPENQVGFLKGIVRPCYSLLMDFV-PEMAPLITYVE 600
>UniRef50_UPI000023CCA1 Cluster: hypothetical protein FG06914.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG06914.1 - Gibberella zeae PH-1
Length = 886
Score = 64.9 bits (151), Expect = 1e-09
Identities = 45/157 (28%), Positives = 79/157 (50%), Gaps = 9/157 (5%)
Frame = +2
Query: 92 LRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLEN------- 250
+R ++I +L+TDM H + L + E + + + D + R Q+ EN
Sbjct: 426 MRNLMISSILATDMGLHFDYMKKLGDVQERLQASNT----TDGWNGR-QIEENKSLACSL 480
Query: 251 LVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMC--DRHNATIEKSQV 424
L+ CAD+SN + + +W +L EEF +Q E E + S M + A++ K Q+
Sbjct: 481 LIKCADISNVARSHEIALQWTYILSEEFSRQASMESELSIQSSLMTPPKQDMASLAKGQL 540
Query: 425 GFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQ 535
GF++ PL++ AD++ P Q +D LE N+ ++
Sbjct: 541 GFMNLFATPLFQGVADIM-PTMQYTVDELEMNKSLFE 576
>UniRef50_Q4SVG8 Cluster: Chromosome undetermined SCAF13758, whole
genome shotgun sequence; n=4; Tetraodontidae|Rep:
Chromosome undetermined SCAF13758, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 928
Score = 64.1 bits (149), Expect = 2e-09
Identities = 48/173 (27%), Positives = 87/173 (50%), Gaps = 2/173 (1%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+L + G I L +E + TL KM+ +L+TD++ HM + + + +
Sbjct: 752 ILNSPGNQILSGLSLDEYKSTL-KMIERAILATDLALHMKRRGEFFELTKNSQFRWED-- 808
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRE-REHGMDISPM 385
+ + D ++ + L+ D+S TKP P+ +R L+ EFF+QGD+E RE ++ S +
Sbjct: 809 --EGHRDLLRSM--LMTACDISAITKPWPVQQRIAELVATEFFEQGDKERRELNIEPSDL 864
Query: 386 CDRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+R I QV FID I L++T A + +L+ +NR+ ++ +
Sbjct: 865 MNREKKDKIPSMQVSFIDAICTQLYQTLAGM-SEYCSPLLEGCRKNREQWKHL 916
>UniRef50_A0CZB5 Cluster: Chromosome undetermined scaffold_32, whole
genome shotgun sequence; n=4; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_32, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 1270
Score = 64.1 bits (149), Expect = 2e-09
Identities = 45/150 (30%), Positives = 76/150 (50%), Gaps = 5/150 (3%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMV--ETKKVAGSG 202
+L++ + NL +EQ Q R+++ID +L TD+ H +LL D ++ + + K G+G
Sbjct: 1088 MLKDSSLNFLSNL-TKEQHQQFRRILIDNILYTDIKVHFTLLKDFESRIKDDVTKPFGTG 1146
Query: 203 VLLLDNYTDRIQVLENLV-HCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS 379
D +++L ++ H AD + K + + W + +EF Q + E G+ +
Sbjct: 1147 -------DDDLKLLTGMIIHTADFNGGAKVFDISRIWSERVNKEFSAQYEEEGRLGIPQT 1199
Query: 380 PMC-DRHNATI-EKSQVGFIDYIVHPLWET 463
P D H I KS++GF IV PLW T
Sbjct: 1200 PFLKDLHKIHIMAKSEMGFFKVIVRPLWFT 1229
>UniRef50_P30645 Cluster: Probable 3',5'-cyclic phosphodiesterase
pde-2; n=5; Eumetazoa|Rep: Probable 3',5'-cyclic
phosphodiesterase pde-2 - Caenorhabditis elegans
Length = 859
Score = 64.1 bits (149), Expect = 2e-09
Identities = 48/165 (29%), Positives = 83/165 (50%)
Frame = +2
Query: 26 KLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGV 205
KLLQ + C I NL + R T+ + +++L+TD+S H+ +KTM+ G
Sbjct: 504 KLLQQEECSILENLPAADFR-TIVNTIREVILATDISAHLRKQERIKTMISE----GYNP 558
Query: 206 LLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPM 385
+ D+ R ++ ++ +DLS+ K KR + EFF QGD E + G+ M
Sbjct: 559 MSFDH---RYLLMCLVMTASDLSDQAKNFHNAKRIAENIYLEFFAQGDLELQLGVKPLEM 615
Query: 386 CDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEEN 520
DR NA + Q+ F+ I P+++ A +V P+ + + ++ N
Sbjct: 616 MDRTNAYVPTVQIDFLFKIGVPVFQLLASVV-PEGRTTSEAIDAN 659
>UniRef50_Q9Y233 Cluster: cAMP and cAMP-inhibited cGMP 3',5'-cyclic
phosphodiesterase 10A; n=44; Euteleostomi|Rep: cAMP and
cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A -
Homo sapiens (Human)
Length = 779
Score = 63.7 bits (148), Expect = 3e-09
Identities = 44/173 (25%), Positives = 86/173 (49%), Gaps = 1/173 (0%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+LQ +G +IF L E Q L +++ +++TD++ + L+ M +T G L
Sbjct: 592 ILQLEGHNIFSTLSSSEYEQVL-EIIRKAIIATDLALYFGNRKQLEEMYQT------GSL 644
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMC 388
L+N + R +V+ ++ DL + TK P+ K + EF+ +GD ++ G+ PM
Sbjct: 645 NLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMM 704
Query: 389 DRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
DR + + Q+GF + + P + T ++ P + +L +N ++ +I
Sbjct: 705 DRDKKDEVPQGQLGFYNAVAIPCYTTLTQIL-PPTEPLLKACRDNLSQWEKVI 756
>UniRef50_UPI0000F1D4E2 Cluster: PREDICTED: similar to
Phosphodiesterase 5A; n=4; Danio rerio|Rep: PREDICTED:
similar to Phosphodiesterase 5A - Danio rerio
Length = 905
Score = 63.3 bits (147), Expect = 3e-09
Identities = 51/175 (29%), Positives = 89/175 (50%), Gaps = 3/175 (1%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+L N G I +L E L+ M+ +L+TD++ + + +T + K+A +
Sbjct: 727 ILNNPGSQILSSLSVNEYMACLQ-MIEKNILATDLA----IFFEKRT--KFFKLAENNSC 779
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISP-- 382
L + R + L+ +D+ TKP P+ KR L+ EF+ QGDRE+ ++I P
Sbjct: 780 LWKDEGHRELLRSMLMTASDICAITKPWPVQKRIAELVATEFYAQGDREKRE-LNIQPID 838
Query: 383 MCDRHNAT-IEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
+ DR NA+ + + QV +ID I PL+E A + + + +NR ++Q M+
Sbjct: 839 VMDRENASRLPQMQVDYIDGICSPLYEALA-FICESCSPLKEGCSKNRKHWQEMV 892
>UniRef50_A5K0J4 Cluster: 3',5'-cyclic-nucleotide phosphodiesterase,
putative; n=5; Plasmodium|Rep: 3',5'-cyclic-nucleotide
phosphodiesterase, putative - Plasmodium vivax
Length = 1001
Score = 62.9 bits (146), Expect = 5e-09
Identities = 41/148 (27%), Positives = 73/148 (49%), Gaps = 1/148 (0%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
+ FK L+ C+IF N + T +K +I +LSTDM H +++ +T +K+
Sbjct: 803 LVFKTLKEKNCNIFEN-YPYNIFTTCKKNIIRAILSTDMKNHFEYISNFRT---SKEFID 858
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+L D Q+ ++ AD+ + T + W + EEF+ QG E+ M
Sbjct: 859 LDILTSDQTW---QIFSLILKAADIGHATLDWNKHYEWTMKINEEFYLQGLLEKSLNMPN 915
Query: 377 SPMCDRHNA-TIEKSQVGFIDYIVHPLW 457
S +CD ++ + SQ+GF+ ++ PL+
Sbjct: 916 SFLCDINSIDKLANSQIGFLKHLCIPLF 943
>UniRef50_A0DIM1 Cluster: Chromosome undetermined scaffold_52, whole
genome shotgun sequence; n=3; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_52, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 779
Score = 62.9 bits (146), Expect = 5e-09
Identities = 45/173 (26%), Positives = 81/173 (46%), Gaps = 5/173 (2%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FK+LQ + +I +L ++Q Q RK I +L TDM KH ++ ++E K
Sbjct: 604 VMFKILQKEKYNILSSL-SQDQCQIFRKYAIANILGTDMKKHFEIV----KLLELKLSKL 658
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ D+ + +VH DL+ +K + ++W + EF Q E++ + I
Sbjct: 659 PDEPFIQKEEDKKFLSSAIVHTCDLTMQSKTFKMAQKWSNRIATEFSDQVAEEKQLSLPI 718
Query: 377 S----PM-CDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEEN 520
+ P+ N + K ++ FI +IV P ++ A ++ + L LE+N
Sbjct: 719 TQHFLPLGTPNFNQLLAKQEISFIKFIVKPAYDLTAQVLQTGLEVPLKNLEDN 771
>UniRef50_Q1DXU2 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 900
Score = 62.9 bits (146), Expect = 5e-09
Identities = 46/158 (29%), Positives = 75/158 (47%), Gaps = 7/158 (4%)
Frame = +2
Query: 92 LRKMVIDMVLSTDMSKH---MSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHC 262
LRK++ID +L+TDM H M L L+ + G D T R + L+ C
Sbjct: 476 LRKLMIDSILATDMGIHNVFMESLGKLQQSYRSNNRTTWGWEPKDIDTYRTLLCALLIKC 535
Query: 263 ADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS----PMCDRHNATIEKSQVGF 430
AD+SN +P + ++W +L EF QG E E GM+ + P + Q+GF
Sbjct: 536 ADISNVARPFHIAEKWTDILQLEFANQGMMEAEIGMETALFGGPPELGNFVKKANGQIGF 595
Query: 431 IDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
++ PL++ AD++ PD + + N+ +Q +
Sbjct: 596 MNVFALPLFDGVADVL-PDMAFAANEIRRNKCRWQMSV 632
>UniRef50_Q4FXD4 Cluster: Putative uncharacterized protein; n=3;
Leishmania|Rep: Putative uncharacterized protein -
Leishmania major strain Friedlin
Length = 1084
Score = 62.5 bits (145), Expect = 6e-09
Identities = 45/157 (28%), Positives = 74/157 (47%)
Frame = +2
Query: 11 TRVAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKV 190
T AF LL D ++ + +V ++ T M +H SL+ ++ K
Sbjct: 687 TATAFHLLATPELDFTRGNMDDTEALEFHGLVAALIGCTFMGRHASLMEQWSRPLQDGKT 746
Query: 191 AGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGM 370
V DR QVL +H AD+ + L + ++W+ ++EE QGD E G+
Sbjct: 747 YDMAVT-----ADRQQVLSLFLHAADIGAQARGLTVARKWLG-IVEEMRAQGDDEAARGL 800
Query: 371 DISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVH 481
+SP R +A++E+ Q+ F++ V PL+ DLVH
Sbjct: 801 PLSPGSSR-SASLERGQIFFMEMFVVPLF----DLVH 832
>UniRef50_A0CG66 Cluster: Chromosome undetermined scaffold_179, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_179, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 1056
Score = 62.5 bits (145), Expect = 6e-09
Identities = 47/169 (27%), Positives = 77/169 (45%), Gaps = 3/169 (1%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V KLL+ D +I L+ E+ R+ +I+ +L TD+ +H L+ D + V+ K
Sbjct: 871 VTLKLLKQDKYNILQGLNAEDLA-IFRQTLIENILFTDIKQHFGLIKDFEQRVKEGKENQ 929
Query: 197 SGVLLLDNYTDRIQVLENL-VHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMD 373
V +++ + VH +D S K L K W + EF Q D E +
Sbjct: 930 ERVF--GQVDGDVKLFTGMIVHTSDFSGAAKVFELSKAWSEKVNMEFQAQFDEEGTRKLI 987
Query: 374 ISP-MCDRHNATI-EKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE 514
+P M D I K+++GF IV PLW + + Q+++D +E
Sbjct: 988 STPFMKDLDKQEIMAKNEMGFFKVIVRPLWASLNEFYGKQLQNVIDNVE 1036
>UniRef50_P16499 Cluster: Rod cGMP-specific 3',5'-cyclic
phosphodiesterase subunit alpha; n=90; Vertebrata|Rep:
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit
alpha - Homo sapiens (Human)
Length = 860
Score = 62.5 bits (145), Expect = 6e-09
Identities = 47/178 (26%), Positives = 91/178 (51%), Gaps = 7/178 (3%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSG-- 202
LL+++ +IF NL+ + + M I +++TD++ + + +V+ K S
Sbjct: 638 LLRDESLNIFQNLNRRQHEHAIHMMDI-AIIATDLALYFKKRTMFQKIVDQSKTYESEQE 696
Query: 203 ---VLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRERE-HGM 370
++L+ I V+ ++ DLS TKP + + L+ EF++QGD ER
Sbjct: 697 WTQYMMLEQTRKEI-VMAMMMTACDLSAITKPWEVQSQVALLVAAEFWEQGDLERTVLQQ 755
Query: 371 DISPMCDRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+ PM DR+ A + K QVGFID++ +++ ++ H + +LD + NR ++++
Sbjct: 756 NPIPMMDRNKADELPKLQVGFIDFVCTFVYKEFSRF-HEEITPMLDGITNNRKEWKAL 812
>UniRef50_Q7QRM3 Cluster: GLP_481_5888_1773; n=1; Giardia lamblia ATCC
50803|Rep: GLP_481_5888_1773 - Giardia lamblia ATCC 50803
Length = 1371
Score = 62.1 bits (144), Expect = 8e-09
Identities = 44/169 (26%), Positives = 79/169 (46%), Gaps = 15/169 (8%)
Frame = +2
Query: 80 QRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTD------RIQV 241
Q + R + ++++L+TDMS H + L L+++ E + +L+++ D R +
Sbjct: 1198 QYREFRALFLEIILATDMSTHFNFLRRLESLDEDLIIK-----ILEHHNDSEIALLRWYI 1252
Query: 242 LENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMD-----ISPMCDRHNAT 406
L+ + DLSNP +P+ + R+ LM EF+ GD E G++ P +
Sbjct: 1253 LKVCIKFGDLSNPCRPIEISTRYAVALMNEFWSLGDLMLECGLEPDKIKTRPQKGEESLI 1312
Query: 407 IEKSQVGFIDYIVHPLWET----WADLVHPDAQDILDTLEENRDYYQSM 541
I SQ+GF IV W W L + D+ L +++Q++
Sbjct: 1313 IANSQIGFTQSIVKGFWTVVERFWKALAGVEFSDLQANLNATVEHWQNV 1361
>UniRef50_Q7Q8G2 Cluster: ENSANGP00000013023; n=2; Diptera|Rep:
ENSANGP00000013023 - Anopheles gambiae str. PEST
Length = 747
Score = 62.1 bits (144), Expect = 8e-09
Identities = 48/171 (28%), Positives = 83/171 (48%), Gaps = 3/171 (1%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
++ + G I N+ E+ + +R ++ D +LSTD++ + +VE S
Sbjct: 576 IINSPGNQILSNMSSEDYSRVIR-VLEDAILSTDLAVYFRKRGAFLNLVEPASEMSSWQA 634
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISP-- 382
+ ++ + V DLS TKP + KR L+ EFF+QGD ER+ ++I+P
Sbjct: 635 --EEPRSLLRAMSMTV--CDLSAITKPWEIEKRVADLVSSEFFEQGDMERQE-LNITPID 689
Query: 383 -MCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYY 532
M + QVGFID I P++E +A L ++D + EN+ ++
Sbjct: 690 IMNREKEDQLPMMQVGFIDSICIPIYEAFATL-SDKLTPLIDGVRENKQHW 739
>UniRef50_A5JZK3 Cluster: 3',5'-cyclic-nucleotide phosphodiesterase,
putative; n=7; Plasmodium|Rep: 3',5'-cyclic-nucleotide
phosphodiesterase, putative - Plasmodium vivax
Length = 783
Score = 61.7 bits (143), Expect = 1e-08
Identities = 47/160 (29%), Positives = 85/160 (53%), Gaps = 7/160 (4%)
Frame = +2
Query: 62 NLHEEEQRQT---LRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDR 232
N+ + E +T LR+ +I ++L+TDMSKH+ +LA + +++ K+ +Y ++
Sbjct: 588 NIFKNESAKTVLNLRQEIIQVILATDMSKHIKILAQFR--IKSIKIR--------SYIEK 637
Query: 233 --IQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRH-NA 403
I L+ ++ ADLS+ + WV L+ EF+ +GD + E G I+P+ DR+ +
Sbjct: 638 NIILCLKMIIKAADLSHNCVDWSEHYLWVKRLVNEFYYEGDEQLEKGYQINPLFDRNSHD 697
Query: 404 TIEKSQVGFIDYIVHPLWETWADLVHPD-AQDILDTLEEN 520
K Q F+ +V PL + L AQ ++D ++ N
Sbjct: 698 NFIKIQRTFLKELVFPLIISLKTLDRTSIAQFMMDKVKRN 737
>UniRef50_A0BZK9 Cluster: Chromosome undetermined scaffold_139, whole
genome shotgun sequence; n=3; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_139, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 987
Score = 61.7 bits (143), Expect = 1e-08
Identities = 46/178 (25%), Positives = 87/178 (48%), Gaps = 2/178 (1%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
+ ++L+N +I VNL+++E R RK +I +LSTDMS+H +LL D E +
Sbjct: 816 LTIQVLKNPQSNILVNLNQQEFRN-FRKGLIANILSTDMSEHFTLLKDF----ENRPTDF 870
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ +L Y ++H +D K L +W + + +EF Q E E G
Sbjct: 871 NDCKILSGY---------IMHTSDFGGAGKKTNLSIKWSSRVNQEFSIQYKLEGELGYPQ 921
Query: 377 SP-MCDRH-NATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
P M D H + KS++GF+ IV P + +++ + + + +++ +++ ++
Sbjct: 922 QPYMKDLHIPHVMAKSEIGFLKVIVRPCYALFSEFLEDRLKHCMANIDDTIQHWEKIV 979
>UniRef50_Q9HCR9 Cluster: Dual 3',5'-cyclic-AMP and -GMP
phosphodiesterase 11A; n=42; Eumetazoa|Rep: Dual
3',5'-cyclic-AMP and -GMP phosphodiesterase 11A - Homo
sapiens (Human)
Length = 934
Score = 60.9 bits (141), Expect = 2e-08
Identities = 47/176 (26%), Positives = 91/176 (51%), Gaps = 2/176 (1%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A +LQ++G +IF NL +E L +++ +L+TD++ + + +V + +
Sbjct: 741 AVMILQSEGHNIFANLSSKEYSD-LMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWN 799
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRER-EHGMDI 376
+ N+ D + + L+ DL TKP + ++ L+ EFF+QGDRER E +
Sbjct: 800 ----IKNHRDIFRSM--LMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTP 853
Query: 377 SPMCDRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
S + DR+ + + Q+ +ID I PL++ V+ + +LD++ NR ++ +
Sbjct: 854 SAIFDRNRKDELPRLQLEWIDSICMPLYQALVK-VNVKLKPMLDSVATNRSKWEEL 908
>UniRef50_A0E2C5 Cluster: Chromosome undetermined scaffold_74, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_74, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 975
Score = 60.1 bits (139), Expect = 3e-08
Identities = 48/169 (28%), Positives = 85/169 (50%), Gaps = 3/169 (1%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
+ KLL +I + EE R+ R+M I +L TD+++H +L+ + ++ KV+ S
Sbjct: 804 SLKLLCVPATNILQSFKGEEFRK-FRRMFISNILYTDITEHFNLIKNFES-----KVSES 857
Query: 200 GVLLLDNYTDRIQVLENLV-HCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
D + I++L ++ H +D + K L K+W + +EF QQ + E + G
Sbjct: 858 NFGQQD---EDIKLLSGMIIHTSDFTGGAKQFELSKQWSFKVNKEFEQQYELEGKLGYPQ 914
Query: 377 SP-MCDRHNATI-EKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEE 517
P M D + K + GF +IV PLW++ + + Q+ +D L+E
Sbjct: 915 LPYMKDLQKLPVMAKQEAGFFKFIVRPLWQSMSKYLDNRLQEQVDYLDE 963
>UniRef50_UPI0000588CD9 Cluster: PREDICTED: hypothetical protein; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 701
Score = 59.7 bits (138), Expect = 4e-08
Identities = 44/170 (25%), Positives = 86/170 (50%), Gaps = 1/170 (0%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+L +G ++F +L + ++ + ++ D+++STD++ +L ++ VA +
Sbjct: 519 ILHREGFNVFSHLPPDTFKKIV-DLIQDIIMSTDLTNFFPNHKELSKLL----VAQTFDW 573
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMC 388
+D++ R + + DL TK P+ ++ V L EEF+ QGD E+E G M
Sbjct: 574 TIDHH--RWSIRNMCMTACDLCASTKMWPIQQQIVECLYEEFYSQGDIEKERGETPIQML 631
Query: 389 DRHN-ATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQ 535
DR N + Q+ F+ + P + ADL+ P++Q +L ++N +Q
Sbjct: 632 DRDNQPNRAQEQIEFLTNVCLPCFSDIADLL-PESQPLLSGCKDNLQQWQ 680
>UniRef50_Q4N6H0 Cluster: Putative uncharacterized protein; n=1;
Theileria parva|Rep: Putative uncharacterized protein -
Theileria parva
Length = 840
Score = 59.7 bits (138), Expect = 4e-08
Identities = 36/137 (26%), Positives = 71/137 (51%), Gaps = 2/137 (1%)
Frame = +2
Query: 71 EEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLEN 250
++E+ + +R+ +I ++LSTD+ H + + +++ + G + D I +
Sbjct: 698 DKEEMKIVRRKIIQLILSTDLEDHFQTITQFRVRRASREFSVEGEI------DTI--CKM 749
Query: 251 LVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCD--RHNATIEKSQV 424
L+ +D+ + L W L++EF+ QG E G+ I+P+CD +HN + K+Q
Sbjct: 750 LIKASDIGSSCMEWRLTLEWSQRLVQEFYTQGLEELSLGLPITPLCDPNKHN-HLPKAQS 808
Query: 425 GFIDYIVHPLWETWADL 475
GF+ V PL+ A++
Sbjct: 809 GFLAIFVIPLYTEIANI 825
>UniRef50_A2DM90 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=2; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein
- Trichomonas vaginalis G3
Length = 457
Score = 59.7 bits (138), Expect = 4e-08
Identities = 41/130 (31%), Positives = 64/130 (49%), Gaps = 1/130 (0%)
Frame = +2
Query: 74 EEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENL 253
+EQ++ + + + +++ STDM KH L K + K GS L RI + +
Sbjct: 307 DEQKENMFRFITEIIFSTDMGKHKFYLE--KIVANIGKFDGSIEL-------RILTCQAI 357
Query: 254 VHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDR-HNATIEKSQVGF 430
+ ADLSN +P + L +E+F QGD E++ G+ IS DR H + K Q+GF
Sbjct: 358 MKLADLSNTCRPFDDSCKMAKRLNDEWFIQGDDEKKLGLPISNGMDRDHPTPLPKGQIGF 417
Query: 431 IDYIVHPLWE 460
+ L E
Sbjct: 418 YKFCTQQLLE 427
>UniRef50_A6S8A0 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 945
Score = 59.3 bits (137), Expect = 6e-08
Identities = 43/160 (26%), Positives = 72/160 (45%), Gaps = 5/160 (3%)
Frame = +2
Query: 80 QRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYT---DRIQVLEN 250
+ + +R ++I +L+TDM H + L + E G + T R
Sbjct: 488 EERDMRHLMISTILATDMGLHFDYMKKLGYLQEKLHENGGVTDGWNGRTIEDQRTLACSL 547
Query: 251 LVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATIE--KSQV 424
L+ CAD+SN + RW +L +EF +Q E++ G+ + IE KSQ+
Sbjct: 548 LIKCADISNVARKFDTATRWTEILTDEFARQASMEQDLGIPTALYAAPVREVIELGKSQI 607
Query: 425 GFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
GF++ PL+ D V P ++ LE N+ ++S I
Sbjct: 608 GFMNMFAIPLFGGVTD-VMPGMAFCVEELERNKAAWESRI 646
>UniRef50_A0D565 Cluster: Chromosome undetermined scaffold_38, whole
genome shotgun sequence; n=5; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_38, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 964
Score = 58.8 bits (136), Expect = 7e-08
Identities = 47/169 (27%), Positives = 77/169 (45%), Gaps = 3/169 (1%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
+ KLL +I N E R RK+ I +L TD+++H +L+ + + + K
Sbjct: 795 SIKLLCAPSTNIIPNFTSVEFRD-FRKLFISNILYTDITEHFNLIKNFEARI---KELNF 850
Query: 200 GVLLLDNYTDRIQVLENLV-HCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
G D I+++ ++ H +D + KP L + W + EF +Q + E + G
Sbjct: 851 GT------EDDIKLMTGMIIHTSDFTGGAKPFNLSREWSTRVNMEFQEQYNLEGKFGYPQ 904
Query: 377 SP-MCDRHNATI-EKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEE 517
P M D I KS+VGF +IV PLW + Q ++ LE+
Sbjct: 905 LPYMKDLDQQPIMAKSEVGFFKFIVRPLWSIMSKFAEDRLQKSVENLEQ 953
>UniRef50_A0E1V7 Cluster: Chromosome undetermined scaffold_74, whole
genome shotgun sequence; n=3; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_74, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 1007
Score = 58.4 bits (135), Expect = 1e-07
Identities = 44/167 (26%), Positives = 78/167 (46%), Gaps = 3/167 (1%)
Frame = +2
Query: 26 KLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGV 205
K+L++D +I N +++ R T RK +I +LSTDM +H +L + ++ +E
Sbjct: 830 KILRDDQTNILCNFSDQDFR-TFRKQLISNILSTDMQEHFKMLKEFESRIEQ-------- 880
Query: 206 LLLDNYTDRIQVLENLV-HCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISP 382
N + + +L ++ H AD + + P + W + +E+ Q E + G P
Sbjct: 881 --YGNDPEDLSLLCGMITHAADFNGTARKWPQSRLWSDKINQEYRAQYAEEGKKGYPQQP 938
Query: 383 -MCDRHNATI-EKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEE 517
M D + K+++GFI IV PL+ Q +D L+E
Sbjct: 939 FMKDLDKLHVMSKNEIGFIKVIVRPLYHQMNQFGKGAFQVCVDNLDE 985
>UniRef50_Q16HU8 Cluster: Camp and camp-inhibited cgmp 3,5-cyclic
phosphodiesterase; n=5; Eumetazoa|Rep: Camp and
camp-inhibited cgmp 3,5-cyclic phosphodiesterase - Aedes
aegypti (Yellowfever mosquito)
Length = 767
Score = 58.0 bits (134), Expect = 1e-07
Identities = 45/172 (26%), Positives = 84/172 (48%), Gaps = 1/172 (0%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+LQ +G +IF L+ E +Q L ++ +L+TD++ L +V+ ++ + +
Sbjct: 592 ILQQEGHNIFSKLNSNEYKQVL-SLIKHCILATDLALFFPNKDKLSKLVDNEQFSWT--- 647
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMC 388
+ + IQ + + ADLS KP + V ++ EF+ QGD E++ G M
Sbjct: 648 -VAEHRMLIQTIA--MTGADLSASAKPWAVQTETVKVIFAEFYDQGDEEKKAGRQPIAMM 704
Query: 389 DRHNATIE-KSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
DR + SQ+GF++ I P + L+ P+ + +L EN + +Q +
Sbjct: 705 DRDQPEQQAASQLGFLNGICIPCYTLLHRLI-PETKPMLTMCNENLERWQQI 755
>UniRef50_Q22CV4 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Tetrahymena thermophila SB210
Length = 1258
Score = 57.6 bits (133), Expect = 2e-07
Identities = 46/170 (27%), Positives = 79/170 (46%), Gaps = 4/170 (2%)
Frame = +2
Query: 23 FKLL-QNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
FK++ Q+ +I NL Q R M+ + +L TD+ +H L+ D +T +
Sbjct: 972 FKIMKQSLDYNILQNLEPITYNQVRRSMISN-ILYTDIKQHFKLILDFETQWKNYDEQ-- 1028
Query: 200 GVLLLDNYTDRIQVLENLV-HCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMD- 373
L N I +L ++ H AD + KP PL ++W + EF Q E + G++
Sbjct: 1029 --LKTTNSEGEIDLLTGMIIHTADFTGAAKPFPLSRQWSEKVNREFHNQYIEEGKRGVEQ 1086
Query: 374 ISPMCDRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEEN 520
S M D + K++ GF+ IV PLW++ D + ++ L ++
Sbjct: 1087 TSFMKDLDILHVMAKAEKGFLSVIVLPLWKSLNDFYKGELNTQIEYLTDS 1136
>UniRef50_UPI0000D8B81A Cluster: UPI0000D8B81A related cluster; n=1;
Mus musculus|Rep: UPI0000D8B81A UniRef100 entry - Mus
musculus
Length = 746
Score = 57.2 bits (132), Expect = 2e-07
Identities = 48/177 (27%), Positives = 91/177 (51%), Gaps = 3/177 (1%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A +LQ++G +IF NL +E L +++ +L+TD++ + L + + +
Sbjct: 573 AVMILQSEGHNIFANLSSKEYSD-LMQLLKQSILATDLTLYFDEKI-LFSRIILQCPLHD 630
Query: 200 GVLLLDNYTDRIQVLENLVHCA-DLSNPTKPLPLYKRWVALLMEEFFQQGDRER-EHGMD 373
G +Y +L +++ A DL TKP + ++ L+ EFF+QGDRER E +
Sbjct: 631 GEAEPGHYKQCDPLLRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERSELKLT 690
Query: 374 ISPMCDRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
S + DR+ + + Q+ +ID I PL++ V+ + +LD++ NR ++ +
Sbjct: 691 PSAIFDRNRKDELPRLQLEWIDSICMPLYQALVK-VNAKLKPMLDSVAANRRKWEEL 746
>UniRef50_A7AS42 Cluster: 3'5'-cyclic nucleotide phosphodiesterase,
putative; n=1; Babesia bovis|Rep: 3'5'-cyclic nucleotide
phosphodiesterase, putative - Babesia bovis
Length = 485
Score = 56.0 bits (129), Expect = 5e-07
Identities = 40/134 (29%), Positives = 66/134 (49%), Gaps = 1/134 (0%)
Frame = +2
Query: 56 FVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRI 235
F L ++ + +RK +I +VL+TDM H + + ++K ++++G+ ++N D
Sbjct: 298 FFGLFNQQDWEIIRKRIIQLVLATDMMTHFTHVNNVK----ERRLSGT-FDYVNNPEDLW 352
Query: 236 QVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDR-HNATIE 412
L LV AD+ + P + W L +EF QGD ER + + DR +A I
Sbjct: 353 FCLVLLVKTADIGHNFLPWCEHLPWTNALFDEFHMQGDEERLLSLPLLLFFDRTRSADIP 412
Query: 413 KSQVGFIDYIVHPL 454
SQ+GF PL
Sbjct: 413 DSQLGFFQGFTSPL 426
>UniRef50_Q7RXW7 Cluster: Putative uncharacterized protein
NCU00478.1; n=1; Neurospora crassa|Rep: Putative
uncharacterized protein NCU00478.1 - Neurospora crassa
Length = 806
Score = 55.2 bits (127), Expect = 9e-07
Identities = 42/160 (26%), Positives = 78/160 (48%), Gaps = 7/160 (4%)
Frame = +2
Query: 80 QRQTLRKMVIDMVLSTDMSKHMSLLADL----KTMVETKKVAGSGVLLLDNYTDRIQVLE 247
+ + LR ++I +L+TDM+ H +A L K + + G +D R+ V
Sbjct: 416 ENRRLRTLMISCILATDMALHFDYMAKLGNLQKLQAQKPDLDGWNEKAVDEA--RVLVCA 473
Query: 248 NLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMD---ISPMCDRHNATIEKS 418
++ CAD+SN + + +W+ LL +E Q E + G I+P + I +S
Sbjct: 474 LIIKCADISNVARRHDIGAQWMHLLNDELILQTQIEMDMGQKTALIAPPSTSLDGRI-RS 532
Query: 419 QVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQS 538
Q+ F++ PL+ AD++ P Q +D +E N ++++
Sbjct: 533 QLKFMELFAFPLFRGVADIL-PGLQFSVDEMELNLTHFEN 571
>UniRef50_Q6BSL2 Cluster: Similar to tr|O94034 Candida albicans
Nucleotide phosphodiesterase; n=2;
Saccharomycetaceae|Rep: Similar to tr|O94034 Candida
albicans Nucleotide phosphodiesterase - Debaryomyces
hansenii (Yeast) (Torulaspora hansenii)
Length = 611
Score = 54.8 bits (126), Expect = 1e-06
Identities = 45/175 (25%), Positives = 86/175 (49%), Gaps = 15/175 (8%)
Frame = +2
Query: 59 VNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQ 238
VN+ + + + +L+ ++I +L+TDM++H + L + +L N + I
Sbjct: 446 VNI-DRKTKISLKNLIISCILATDMAEHFEYIDKLAHFKADR------YMLEVNRVNLIS 498
Query: 239 VLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMD-ISPMCDRH------ 397
L L+ CAD+SN T+PL + +W +L EF + E++ + ++P D H
Sbjct: 499 SL--LIKCADISNVTRPLRVSSQWALVLGREFCEVSTLEKKLAHNQLTPELDIHYDKVPS 556
Query: 398 --------NATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQS 538
N I K Q+ FI+ L+ A+L+ P+ + D ++EN++++ S
Sbjct: 557 ALPDILQANPDIHKGQIFFINTFAENLFNNIAELL-PELRYTCDIVQENKEFWLS 610
>UniRef50_A0CU34 Cluster: Chromosome undetermined scaffold_28, whole
genome shotgun sequence; n=4; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_28, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 903
Score = 54.4 bits (125), Expect = 2e-06
Identities = 39/152 (25%), Positives = 71/152 (46%), Gaps = 3/152 (1%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V +KLL + CD F+ + +RK +++ VL+TD H +L D +E K
Sbjct: 724 VTYKLLALEQCD-FLESVPRADKLMIRKYIVNNVLATDNQFHFKILND----IEIKFAQS 778
Query: 197 SG-VLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMD 373
G + ++ +++ + L H AD K + + W L EF Q E G+
Sbjct: 779 QGDPKIFESDDNKLLLSGFLTHAADFFGAAKSYQVARTWSERLRREFQAQSQLEDIVGIA 838
Query: 374 ISPMCDRHNATIE--KSQVGFIDYIVHPLWET 463
+P + ++ K+++GF+ IV P++E+
Sbjct: 839 QTPYLRNLDDEVQYAKNEIGFLKVIVKPIYES 870
>UniRef50_Q9VFI9 Cluster: CG8279-PA; n=8; Endopterygota|Rep: CG8279-PA
- Drosophila melanogaster (Fruit fly)
Length = 1131
Score = 54.0 bits (124), Expect = 2e-06
Identities = 49/174 (28%), Positives = 80/174 (45%), Gaps = 3/174 (1%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+L ++G +IF L E+ R + K V +LSTD++ + +VE + G
Sbjct: 810 ILNSEGNNIFQALSPEDYRSVM-KTVESAILSTDLAMYFKKRNAFLELVENGEFDWQG-- 866
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISP-- 382
+ D + + ++ D+S KP + + L+ +EFF QGD E+ ++ P
Sbjct: 867 --EEKKDLLCGM--MMTACDVSAIAKPWEVQHKVAKLVADEFFDQGDLEKLQ-LNTQPVA 921
Query: 383 MCDRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
M DR + K QVGFID I PL+ D P + + ENR +Q +
Sbjct: 922 MMDRERKDELPKMQVGFIDVICLPLYRVLCD-TFPWITPLYEGTLENRRNWQDL 974
>UniRef50_Q0V6F8 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 953
Score = 54.0 bits (124), Expect = 2e-06
Identities = 40/161 (24%), Positives = 76/161 (47%), Gaps = 10/161 (6%)
Frame = +2
Query: 92 LRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLEN------L 253
+RK++I+ +L+TDM H + DL + + K G D + +++ + L
Sbjct: 461 MRKLMINNILATDMGLHFKYMTDLGNL-QQKIAHDQGDT--DGWNSKMKEEQKDLACGVL 517
Query: 254 VHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI----SPMCDRHNATIEKSQ 421
+ CAD+ N + +W +L +EF QG E+E M P + +SQ
Sbjct: 518 IKCADICNVARKFDTAAKWANILTDEFSNQGIMEQELQMPSCLFGGPPVRDDLIKLGESQ 577
Query: 422 VGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
+GF++ PL+E D++ P + +D + N+ +++ I
Sbjct: 578 IGFMNIFACPLFEAVTDIL-PAMRFAVDEILANKTVWENKI 617
>UniRef50_O94034 Cluster: Nucleotide phosphodiesterase; n=4;
Saccharomycetales|Rep: Nucleotide phosphodiesterase -
Candida albicans (Yeast)
Length = 571
Score = 54.0 bits (124), Expect = 2e-06
Identities = 46/177 (25%), Positives = 80/177 (45%), Gaps = 16/177 (9%)
Frame = +2
Query: 50 DIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTD 229
D+ EE+ T+R ++I +L+TDM +H + LK+ ++ DN
Sbjct: 397 DLLTCTIEEKSELTIRSLIISSILATDMGEHNEYVNRLKSFKTHNEILNH-----DNTVK 451
Query: 230 RIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQ--------QGDREREHGMDISPM 385
I L L+ CAD+SN T+PL + +W +L EF + + D + + D++
Sbjct: 452 LISAL--LIKCADISNVTRPLRVSAQWAMVLSREFAEVELLKSVIKKDIDLDFTKDLTYD 509
Query: 386 CDRH--------NATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYY 532
H I K Q+ FI+ L+ + +DL+ P Q D + EN+ ++
Sbjct: 510 HVPHELREILEIQPDIHKGQIFFINLFAENLFNSVSDLL-PQLQYTCDIIMENKLFW 565
>UniRef50_A2DCH1 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1106
Score = 53.2 bits (122), Expect = 4e-06
Identities = 45/156 (28%), Positives = 76/156 (48%), Gaps = 1/156 (0%)
Frame = +2
Query: 56 FVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRI 235
F L E++ + L +L+TDMSKH L+ E KK+A S ++ R+
Sbjct: 953 FEFLTEKDAKNELLSEASRFILATDMSKHFDLIE------EAKKLADSDNFSFEDKETRM 1006
Query: 236 QVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPM-CDRHNATIE 412
+ E L+ ADL + + K L +EFF +GD + + +R N
Sbjct: 1007 KTTEILIKSADLGSANRNGD--KADKKGLPDEFFAEGDLSKVKDIVYDKEGNERKNIHWG 1064
Query: 413 KSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEEN 520
S++ F++ ++ P +ET A L+ PD +D+L ++EN
Sbjct: 1065 DSEIPFMNDVLVPTFETLAMLL-PDLEDMLKQVKEN 1099
>UniRef50_P91119 Cluster: Probable 3',5'-cyclic phosphodiesterase
pde-5; n=3; Caenorhabditis|Rep: Probable 3',5'-cyclic
phosphodiesterase pde-5 - Caenorhabditis elegans
Length = 710
Score = 53.2 bits (122), Expect = 4e-06
Identities = 35/125 (28%), Positives = 61/125 (48%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+LQ DG +I +L E+ ++TL ++ +L+TD++ S A L +++ +
Sbjct: 562 ILQQDGHNILKSLSSEDYKKTL-SLIKHCILATDLALFFSNKAKLNVILD------NNTF 614
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMC 388
++ R+ ++ DL KP + V ++ EEF+ QGD ER G + PM
Sbjct: 615 DINRQEHRLLTQAVMMTGCDLVASAKPWNIQTETVKVIFEEFYDQGDAERLSGKEPIPMM 674
Query: 389 DRHNA 403
DR A
Sbjct: 675 DRQQA 679
>UniRef50_Q9VJ79 Cluster: Dual 3',5'-cyclic-AMP and -GMP
phosphodiesterase 11; n=9; Eumetazoa|Rep: Dual
3',5'-cyclic-AMP and -GMP phosphodiesterase 11 -
Drosophila melanogaster (Fruit fly)
Length = 1451
Score = 53.2 bits (122), Expect = 4e-06
Identities = 44/171 (25%), Positives = 82/171 (47%), Gaps = 3/171 (1%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+L + G I NL ++ + +R ++ D +LSTD++ + V +
Sbjct: 939 ILNSPGNQILANLSSDDYCRVIR-VLEDAILSTDLAVYFKKRGPFLESVSQP----TSYW 993
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISP-- 382
+ + ++ + V DLS TKP + KR L+ EFF+QGD E++ ++I+P
Sbjct: 994 VAEEPRALLRAMSMTV--CDLSAITKPWEIEKRVADLVSSEFFEQGDMEKQE-LNITPID 1050
Query: 383 -MCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYY 532
M + QV FID I P++E +A L + +++ + +NR ++
Sbjct: 1051 IMNREKEDELPMMQVNFIDSICLPIYEAFATL-SDKLEPLVEGVRDNRGHW 1100
>UniRef50_Q2H9G5 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 894
Score = 52.4 bits (120), Expect = 7e-06
Identities = 41/152 (26%), Positives = 73/152 (48%), Gaps = 5/152 (3%)
Frame = +2
Query: 92 LRKMVIDMVLSTDMSKH---MSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHC 262
+R ++I +L+TDM H M L DL+ + + N + L+ C
Sbjct: 456 MRHLMISSILATDMGLHFDYMRKLGDLQGKLRPNNSTEDWDEGVKN-EQKALTCALLIKC 514
Query: 263 ADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCD--RHNATIEKSQVGFID 436
AD+SN T+ +W+ +L EEF +Q E E + S M + + ++ SQ+ F++
Sbjct: 515 ADISNVTRRHDAAIQWMKILSEEFSRQATMENELEIKTSLMSEPKQDKLSLTTSQLKFMN 574
Query: 437 YIVHPLWETWADLVHPDAQDILDTLEENRDYY 532
PL++ AD++ P Q +D L N++ +
Sbjct: 575 LFALPLFQGVADIL-PAMQYCVDELFLNKELF 605
>UniRef50_UPI0001554EBF Cluster: PREDICTED: similar to cyclic
nucleotide phophodiesterase, partial; n=1;
Ornithorhynchus anatinus|Rep: PREDICTED: similar to
cyclic nucleotide phophodiesterase, partial -
Ornithorhynchus anatinus
Length = 340
Score = 51.2 bits (117), Expect = 2e-05
Identities = 29/92 (31%), Positives = 49/92 (53%)
Frame = +2
Query: 68 HEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLE 247
H E +R R +VI+ +L+TD+ KH LA+ + V SG+ N DR+ V +
Sbjct: 254 HVEFKR--FRFLVIEAILATDLKKHFDFLAEFNA--KANDVNSSGIEW-SNENDRLLVCQ 308
Query: 248 NLVHCADLSNPTKPLPLYKRWVALLMEEFFQQ 343
+ AD++ P K L+ +W ++ EF++Q
Sbjct: 309 VCIKLADINGPAKVRDLHLKWTEGIVNEFYEQ 340
>UniRef50_Q7YYN8 Cluster: Phosphdiesterase, possible; n=2;
Cryptosporidium|Rep: Phosphdiesterase, possible -
Cryptosporidium parvum
Length = 1001
Score = 51.2 bits (117), Expect = 2e-05
Identities = 38/147 (25%), Positives = 66/147 (44%)
Frame = +2
Query: 92 LRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADL 271
L KM+I+ +L TDM +H L DL + S + ++ ++ +L L+H D+
Sbjct: 848 LHKMMINSILFTDMFQH-KYLRDLVLNFNKNYSSNSRSIEVEAQKKKLYLLI-LLHSVDI 905
Query: 272 SNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATIEKSQVGFIDYIVHP 451
SNP +Y +W L+ EE Q + + ++ D ++ T K Q FI I P
Sbjct: 906 SNPLMNTNIYLKWSRLVYEELENQKKLKLMLNISLNDTTDTYDYT--KLQTSFISSICIP 963
Query: 452 LWETWADLVHPDAQDILDTLEENRDYY 532
++ Q+ + L N +Y+
Sbjct: 964 YFQALLKFDPEIVQECIQNLYFNNEYF 990
>UniRef50_A3FPW6 Cluster: Phosphdiesterase, putative; n=1;
Cryptosporidium parvum Iowa II|Rep: Phosphdiesterase,
putative - Cryptosporidium parvum Iowa II
Length = 1206
Score = 51.2 bits (117), Expect = 2e-05
Identities = 38/147 (25%), Positives = 66/147 (44%)
Frame = +2
Query: 92 LRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADL 271
L KM+I+ +L TDM +H L DL + S + ++ ++ +L L+H D+
Sbjct: 1053 LHKMMINSILFTDMFQH-KYLRDLVLNFNKNYSSNSRSIEVEAQKKKLYLLI-LLHSVDI 1110
Query: 272 SNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATIEKSQVGFIDYIVHP 451
SNP +Y +W L+ EE Q + + ++ D ++ T K Q FI I P
Sbjct: 1111 SNPLMNTNIYLKWSRLVYEELENQKKLKLMLNISLNDTTDTYDYT--KLQTSFISSICIP 1168
Query: 452 LWETWADLVHPDAQDILDTLEENRDYY 532
++ Q+ + L N +Y+
Sbjct: 1169 YFQALLKFDPEIVQECIQNLYFNNEYF 1195
>UniRef50_A2G4P7 Cluster: GAF domain containing protein; n=1;
Trichomonas vaginalis G3|Rep: GAF domain containing
protein - Trichomonas vaginalis G3
Length = 1554
Score = 50.4 bits (115), Expect = 3e-05
Identities = 41/174 (23%), Positives = 77/174 (44%), Gaps = 3/174 (1%)
Frame = +2
Query: 26 KLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGV 205
++++ + C+I N+ E+EQR + K +TD+S+H ++ L+ +E + S
Sbjct: 1152 EIIRVEECNILENIKEDEQRN-IWKDTFRFAHATDLSRHFEIMDTLQQCLEEEDGFDSS- 1209
Query: 206 LLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPM 385
T +L+ ++ CADL + PL + +FF G+ R GM
Sbjct: 1210 ----KETHLNAMLDAVMKCADLHDVILPLNELEEKRYEFSRDFFMFGEILRCKGMFFDGE 1265
Query: 386 CDRHNATIEKSQVGFIDYIVHPLWETWADLV---HPDAQDILDTLEENRDYYQS 538
R ++S +GF YI PL+ + PD ++L + R+ ++
Sbjct: 1266 ASRTTINQKESNLGFFMYICLPLFAAVGKSIAGFEPDVDNLLAAIAHFREQLEN 1319
>UniRef50_UPI000065E700 Cluster: Cone cGMP-specific 3',5'-cyclic
phosphodiesterase subunit alpha' (EC 3.1.4.35) (cGMP
phosphodiesterase 6C).; n=1; Takifugu rubripes|Rep: Cone
cGMP-specific 3',5'-cyclic phosphodiesterase subunit
alpha' (EC 3.1.4.35) (cGMP phosphodiesterase 6C). -
Takifugu rubripes
Length = 937
Score = 50.0 bits (114), Expect = 3e-05
Identities = 30/94 (31%), Positives = 50/94 (53%), Gaps = 2/94 (2%)
Frame = +2
Query: 266 DLSNPTKPLPLYKRWVALLMEEFFQQGDRERE-HGMDISPMCDRHNA-TIEKSQVGFIDY 439
DLS TKP + + ++ EF++QGD ER PM DR+ A + K Q GFID+
Sbjct: 830 DLSAITKPWEVQSKVALMVAAEFWEQGDLERSVLDQQPIPMMDRNCAEQLPKMQCGFIDF 889
Query: 440 IVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+ +++ ++ H + Q + D L NR ++ +
Sbjct: 890 VCSFVYKEFSRF-HKEIQPMFDGLNNNRSHWNEL 922
>UniRef50_Q2V2M6 Cluster: CGMP-specific phosphodiesterase; n=3;
Plasmodium|Rep: CGMP-specific phosphodiesterase -
Plasmodium falciparum
Length = 884
Score = 49.6 bits (113), Expect = 5e-05
Identities = 39/148 (26%), Positives = 72/148 (48%), Gaps = 3/148 (2%)
Frame = +2
Query: 23 FKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSG 202
FK L+N +IF + + + +K +I +LSTDM H ++D +T E
Sbjct: 688 FKTLKNPNYNIFEH-YPYHIFISCKKNIIKAILSTDMKNHFEYISDFRTSKE-------- 738
Query: 203 VLLLDNYT-DRI-QVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ DN + D+I Q+ ++ +D+ + T + W + EEF+ QG E+ +
Sbjct: 739 FIDYDNLSNDQIWQIFCLILKASDIGHSTLEWNKHLEWTLKINEEFYLQGLLEKSLNIQN 798
Query: 377 SPMCDRHNAT-IEKSQVGFIDYIVHPLW 457
S +CD + + SQ+ F+ ++ PL+
Sbjct: 799 SFLCDINTMNKLALSQIDFLKHLCIPLF 826
>UniRef50_Q22VA7 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein
- Tetrahymena thermophila SB210
Length = 624
Score = 48.8 bits (111), Expect = 8e-05
Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 1/90 (1%)
Frame = +2
Query: 215 DNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISP-MCD 391
+N+ DR +L ++H D+ NP Y W L+ +EF Q +E ++ + ++ +
Sbjct: 505 ENFEDRRFLLNIILHACDIGNPCLEYNNYMNWSYLITQEFSDQTQKEEQYNLPVTGFLIY 564
Query: 392 RHNATIEKSQVGFIDYIVHPLWETWADLVH 481
+ T Q F +V P+W+ D H
Sbjct: 565 KDKLTFLNGQTFFCKAMVLPIWQEIGDFFH 594
Score = 38.7 bits (86), Expect = 0.086
Identities = 17/53 (32%), Positives = 32/53 (60%), Gaps = 1/53 (1%)
Frame = +2
Query: 23 FKLLQ-NDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVE 178
F++LQ N+ + F L ++ + Q +++++ + STDM KH L A LK ++
Sbjct: 394 FQILQSNNELNYFTALKDQNKIQQFKRIIVSCITSTDMQKHSKLTAKLKRRIQ 446
>UniRef50_UPI0000D555D7 Cluster: PREDICTED: similar to
phosphodiesterase 10A; n=4; Tribolium castaneum|Rep:
PREDICTED: similar to phosphodiesterase 10A - Tribolium
castaneum
Length = 745
Score = 48.4 bits (110), Expect = 1e-04
Identities = 43/155 (27%), Positives = 70/155 (45%), Gaps = 1/155 (0%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VA LL ++ + +L +EE + LR + +++TD L + +K+
Sbjct: 579 VAMLLLDHN--KVLTHLSKEEY-EVLRTEIKQAIIATDP------LVYFANQINLEKICN 629
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ N T R + ++ ADLS KP + KR L E + QGD E+E G+
Sbjct: 630 THSFDWGNETHRYYLKGTMMMVADLSGMCKPFLVSKRITDNLYAECYLQGDLEKEMGLCP 689
Query: 377 SPMCDRHNAT-IEKSQVGFIDYIVHPLWETWADLV 478
M DR + I + QV FI ++ P + A L+
Sbjct: 690 LSMMDRDKSNFIPEDQVTFITTVILPCLDILAQLL 724
>UniRef50_UPI00006CD10E Cluster: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein; n=1; Tetrahymena
thermophila SB210|Rep: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein - Tetrahymena
thermophila SB210
Length = 516
Score = 48.4 bits (110), Expect = 1e-04
Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 2/97 (2%)
Frame = +2
Query: 236 QVLENL-VHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCD-RHNATI 409
Q L N+ +H D+ NP Y W LL +EF Q +E + G+ ++
Sbjct: 410 QFLTNIMIHACDIGNPCYSFDNYMNWCYLLSQEFHDQTIKEEQKGVPVTTFLQYTGKQAF 469
Query: 410 EKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEEN 520
K Q+ F ++ PLW+ +L+ P Q + + L +N
Sbjct: 470 RKGQIFFSSSLLMPLWKELGNLI-PQLQVLPEQLAKN 505
Score = 32.3 bits (70), Expect = 7.4
Identities = 13/45 (28%), Positives = 24/45 (53%)
Frame = +2
Query: 35 QNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKT 169
+N DI + + +K+++ +L+TDM +H + DLKT
Sbjct: 314 RNPQFDIASKFQDAAKLNKFKKLLVSNILATDMGRHGQFITDLKT 358
>UniRef50_A2FQB0 Cluster: GAF domain containing protein; n=1;
Trichomonas vaginalis G3|Rep: GAF domain containing
protein - Trichomonas vaginalis G3
Length = 1042
Score = 47.6 bits (108), Expect = 2e-04
Identities = 37/151 (24%), Positives = 71/151 (47%), Gaps = 1/151 (0%)
Frame = +2
Query: 26 KLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGV 205
+++ + C+IF N+ + M+I M++ TD+ ++++
Sbjct: 880 RVVNSPECNIFSNMTHATMAK-FWAMMIRMIIDTDLEVFSQVMSNNSL----------NN 928
Query: 206 LLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPM 385
L + N RI+VL ++ +++SN +P + RW+ L E+++QGD E+ GM + +
Sbjct: 929 LDMKNQNSRIKVLSLILILSNISNVARPFDVAMRWLDCLSTEYYKQGDIEKSLGMKYTNV 988
Query: 386 C-DRHNATIEKSQVGFIDYIVHPLWETWADL 475
+R K Q FI+ PL + A L
Sbjct: 989 ANNRALPDKPKEQSNFINTYALPLSKVVATL 1019
>UniRef50_A0EF18 Cluster: Chromosome undetermined scaffold_92, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_92, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 929
Score = 47.6 bits (108), Expect = 2e-04
Identities = 24/91 (26%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
Frame = +2
Query: 251 LVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISP-MCDRHNATI-EKSQV 424
++H +D + + P+ K+W + +EF Q + E G+ P M D ++ KS++
Sbjct: 823 IIHTSDFAGASAKWPISKQWSLRVNQEFQAQFEEEGRLGLPQQPFMKDLQKISVLSKSEI 882
Query: 425 GFIDYIVHPLWETWADLVHPDAQDILDTLEE 517
GF + V PL+ + + + QD +D ++E
Sbjct: 883 GFYKFFVRPLYVSLSKFMDHQLQDRIDNIDE 913
>UniRef50_Q53S13 Cluster: Putative uncharacterized protein PDE11A;
n=4; Deuterostomia|Rep: Putative uncharacterized protein
PDE11A - Homo sapiens (Human)
Length = 125
Score = 47.6 bits (108), Expect = 2e-04
Identities = 31/99 (31%), Positives = 54/99 (54%), Gaps = 2/99 (2%)
Frame = +2
Query: 251 LVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRER-EHGMDISPMCDRHNA-TIEKSQV 424
L+ DL TKP + ++ L+ EFF+QGDRER E + S + DR+ + + Q+
Sbjct: 3 LMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQL 62
Query: 425 GFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+ID I PL++ V+ + +LD++ NR ++ +
Sbjct: 63 EWIDSICMPLYQALVK-VNVKLKPMLDSVATNRSKWEEL 100
>UniRef50_Q4N806 Cluster: 3',5' cyclic nucleotide phosphodiesterase,
putative; n=2; Theileria|Rep: 3',5' cyclic nucleotide
phosphodiesterase, putative - Theileria parva
Length = 450
Score = 46.4 bits (105), Expect = 4e-04
Identities = 30/105 (28%), Positives = 52/105 (49%)
Frame = +2
Query: 89 TLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCAD 268
+LRK +I ++LSTDM H + ++K K++ G + N D +L + AD
Sbjct: 268 SLRKRIIQLILSTDMINHFLHIDNVKE----KRLQGK--FDIKNDDDFWLLLVLCIKAAD 321
Query: 269 LSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNA 403
+ + P + W +L EEF++QGD E+ + DR+ +
Sbjct: 322 IGHNFLPWADHLPWTQVLFEEFYKQGDEEKMQSISPLMFFDRNES 366
>UniRef50_A2FK96 Cluster: GAF domain containing protein; n=3;
Trichomonas vaginalis G3|Rep: GAF domain containing
protein - Trichomonas vaginalis G3
Length = 1174
Score = 45.6 bits (103), Expect = 7e-04
Identities = 29/114 (25%), Positives = 54/114 (47%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A K + C+I +L+ + Q +VID +LST+ S+H ++ D K A
Sbjct: 1009 AIKTIGKPSCNILSSLNAD-QLHDFWVLVIDTILSTETSQHQKIIDDAKL-----SFAPD 1062
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRERE 361
L L N R ++++ ++ +L++ +P K W ++L +EF + E
Sbjct: 1063 ETLPLANTQQRARMMKLILRIGNLASCARPFDSTKSWSSVLSDEFTDDSENAGE 1116
>UniRef50_Q4RG61 Cluster: Chromosome 2 SCAF15106, whole genome shotgun
sequence; n=3; Tetraodontidae|Rep: Chromosome 2
SCAF15106, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 899
Score = 45.2 bits (102), Expect = 0.001
Identities = 37/144 (25%), Positives = 71/144 (49%), Gaps = 6/144 (4%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMS---KHMSLLADLKTMVETKKVAGS 199
L+ + +IF NL ++ Q + ++ + +++TD++ K ++ ++ E
Sbjct: 687 LMAEETLNIFCNL-QKRQFEHVQHLFDVCIIATDLALYFKKRTMFQNIVNATEPMADEKE 745
Query: 200 GVLLLDNYTDRIQ-VLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRERE-HGMD 373
+ + N R + V+ ++ DLS TKP + + ++ EF++QGD ER
Sbjct: 746 AIGYVSNNPIRKEIVMAMMMTGCDLSAITKPWEVQSKVALMVAAEFWEQGDLERNVLDQQ 805
Query: 374 ISPMCDRHNA-TIEKSQVGFIDYI 442
PM DR+ A + K Q GFID++
Sbjct: 806 PIPMMDRNCAEQLPKMQCGFIDFV 829
>UniRef50_A2E0V4 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein
- Trichomonas vaginalis G3
Length = 438
Score = 45.2 bits (102), Expect = 0.001
Identities = 21/98 (21%), Positives = 52/98 (53%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
+A +++ ++ ++ L+++E + + ++I +L+TDM++H +L K ++ +
Sbjct: 288 IAIQIMSHEETNLLATLNQDECNE-IWSLIIQYILATDMARHFEIL---KRFID---IYD 340
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 310
+ R+ +L ++ C D+SN ++P L RW
Sbjct: 341 DSDFTTQRHDHRVMLLYMILKCGDISNVSRPFELVDRW 378
>UniRef50_Q8IKD3 Cluster: Cyclic nucleotide phosphodiesterase,
putative; n=1; Plasmodium falciparum 3D7|Rep: Cyclic
nucleotide phosphodiesterase, putative - Plasmodium
falciparum (isolate 3D7)
Length = 813
Score = 44.4 bits (100), Expect = 0.002
Identities = 35/129 (27%), Positives = 58/129 (44%), Gaps = 6/129 (4%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVN-----LHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVET 181
+ F +LQ G D +N L E+ +RK +I++++STDM H + K +
Sbjct: 533 ITFSILQLIGFDFLINNEDTKLVEKNNYTNMRKFIIELIISTDMKLHFEYVDIFK---KR 589
Query: 182 KKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRERE 361
KK + + TD I + + AD+ + + +W L+ EEFF Q E
Sbjct: 590 KKSQNFDI----SDTDAINLGTINIKLADIGHTCLKWKDHAKWTMLVSEEFFSQKRVEEL 645
Query: 362 H-GMDISPM 385
H +I P+
Sbjct: 646 HKNKNIDPL 654
>UniRef50_Q57ZK5 Cluster: 3', 5'-cyclic nucleotide
phosphodiesterase, putative; n=1; Trypanosoma
brucei|Rep: 3', 5'-cyclic nucleotide phosphodiesterase,
putative - Trypanosoma brucei
Length = 909
Score = 42.3 bits (95), Expect = 0.007
Identities = 23/77 (29%), Positives = 41/77 (53%)
Frame = +2
Query: 227 DRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNAT 406
DR+ L L+ AD ++ + +W+ +L EE Q ER G+ ++P D +
Sbjct: 506 DRVDALSLLLLAADFGVISRGADIAAKWL-VLTEEHAAQAQEERRRGLPVTPGFDL-PTS 563
Query: 407 IEKSQVGFIDYIVHPLW 457
+ +SQ+ F+D +V PL+
Sbjct: 564 VGRSQIAFLDSVVIPLF 580
>UniRef50_A2E4B2 Cluster: Response regulator receiver domain
containing protein; n=1; Trichomonas vaginalis G3|Rep:
Response regulator receiver domain containing protein -
Trichomonas vaginalis G3
Length = 637
Score = 42.3 bits (95), Expect = 0.007
Identities = 42/166 (25%), Positives = 71/166 (42%), Gaps = 2/166 (1%)
Frame = +2
Query: 50 DIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTD 229
++F +++ TLR + VL+TD SK LA A + + +N
Sbjct: 407 EVFSFSIDDQDFSTLRATFLSNVLATDYSKLQKFLAK----------AANIKMDWENKEH 456
Query: 230 RIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDR--HNA 403
R L+ L +DLS + W ++ +E + QGD ER+ M P+ DR +
Sbjct: 457 RQIALQLLTLMSDLSFAIRNWKTTSYWYGMMRDEHYIQGDMERKRNMKSIPLMDRRANRP 516
Query: 404 TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
E + F + +V P+++ A + Q +L L+ N D M
Sbjct: 517 NTELIKTHF-EIMVMPVFQLGAKIFPEFEQLLLLQLQVNHDIILEM 561
>UniRef50_A5K353 Cluster: 3',5'-cyclic-nucleotide phosphodiesterase,
putative; n=5; Plasmodium|Rep: 3',5'-cyclic-nucleotide
phosphodiesterase, putative - Plasmodium vivax
Length = 803
Score = 41.9 bits (94), Expect = 0.009
Identities = 33/121 (27%), Positives = 52/121 (42%), Gaps = 5/121 (4%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVN-----LHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVET 181
+ F +LQ G D +N L E+ LRK +I++++STDM H + K
Sbjct: 512 ITFSILQLIGHDFLINSEDTKLVEKNSYANLRKFIIELIISTDMKLHFEYVDIFK----- 566
Query: 182 KKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRERE 361
K+ + D D I + + AD+ + + +W L+ EEFF Q E
Sbjct: 567 KRKRSENFDISDR--DAINLGTINIKVADIGHTCLKWRDHAKWTMLVSEEFFSQKKVEEL 624
Query: 362 H 364
H
Sbjct: 625 H 625
>UniRef50_A2E5S0 Cluster: GAF domain containing protein; n=1;
Trichomonas vaginalis G3|Rep: GAF domain containing
protein - Trichomonas vaginalis G3
Length = 1275
Score = 41.9 bits (94), Expect = 0.009
Identities = 35/171 (20%), Positives = 82/171 (47%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+L+ +I L+ ++ Q+ KM+I ++L T+M+KH + + L++++ K+ +
Sbjct: 1119 ILERSEENILETLNADDS-QSCWKMIISLILGTNMAKHFNTVTTLQSLIFPNKMIN---M 1174
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMC 388
L+ + R+ +++ ++ +D S + P+ +R +G + + D + +
Sbjct: 1175 KLEEH--RLLIMQFIIKASDASYACRNFPVCQR-----------EGTKAYKMFTDKTAIG 1221
Query: 389 DRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+ SQVGFI P++ T V P +L+ ++ N Y++ +
Sbjct: 1222 KLFQRYLVNSQVGFIILYAEPMF-TLLTHVFPSVDPLLEQVKLNLQYWKQL 1271
>UniRef50_Q5C1P7 Cluster: SJCHGC07646 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC07646 protein - Schistosoma
japonicum (Blood fluke)
Length = 219
Score = 40.7 bits (91), Expect = 0.021
Identities = 21/47 (44%), Positives = 33/47 (70%), Gaps = 1/47 (2%)
Frame = +2
Query: 17 VAFKL-LQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLL 154
VAF+L L++ +IF NL EE R T+R ++DMVL+T+M +H ++
Sbjct: 62 VAFELTLRSPDINIFQNLTREEYR-TMRSYIVDMVLATEMVRHFDIV 107
Score = 39.9 bits (89), Expect = 0.037
Identities = 15/44 (34%), Positives = 26/44 (59%)
Frame = +2
Query: 212 LDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQ 343
L +R + ++ C+D++NPT+PL + K W + EE+F Q
Sbjct: 165 LSTVENRSLIKRLIIKCSDVNNPTRPLSICKEWAMRIAEEYFCQ 208
>UniRef50_A7T5L5 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 269
Score = 40.7 bits (91), Expect = 0.021
Identities = 15/39 (38%), Positives = 26/39 (66%)
Frame = +2
Query: 347 DREREHGMDISPMCDRHNATIEKSQVGFIDYIVHPLWET 463
DRE+ G+ ++P DR T +Q+GFI +++ PL+E+
Sbjct: 104 DREKAEGLPVAPFMDRDKVTKPTAQIGFIKFVLTPLFES 142
>UniRef50_Q4DUD4 Cluster: CAMP-specific phosphodiesterase, putative;
n=2; Trypanosoma|Rep: CAMP-specific phosphodiesterase,
putative - Trypanosoma cruzi
Length = 654
Score = 39.9 bits (89), Expect = 0.037
Identities = 45/168 (26%), Positives = 77/168 (45%), Gaps = 4/168 (2%)
Frame = +2
Query: 35 QNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLL 214
+N D+F N + Q LR+++++ VL T SLL DL +KVA + + L
Sbjct: 267 ENRFIDLFANSGTQPFSQFLREILVETVLGTAPRLRSSLLRDL------EKVAVADAVEL 320
Query: 215 DNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDR 394
+ D +L +V AD + +P + L++ E+ ++ E + GMD P+
Sbjct: 321 N---DIPILLAAVVILADNALALRPHAQFVNLAGLMVTEWLREAYEEEQRGMD--PLVPN 375
Query: 395 HNATIEKSQVGF-IDYI---VHPLWETWADLVHPDAQDILDTLEENRD 526
I ++ +G +DY + PL LV QD+ D +E N +
Sbjct: 376 LRKQIYENGLGMAVDYCKVWLRPLITNIRALV---PQDLYDNMEGNTE 420
>UniRef50_Q758Y3 Cluster: ADR395Cp; n=1; Eremothecium gossypii|Rep:
ADR395Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 480
Score = 37.5 bits (83), Expect = 0.20
Identities = 31/107 (28%), Positives = 55/107 (51%), Gaps = 5/107 (4%)
Frame = +2
Query: 29 LLQNDGCDIFVNL---HEEEQRQTLRKMVI-DMVLSTDMSKHMSLLADLKTMVETKKVAG 196
+L+N D+F+++ H E +++ I D ++STDM+ H L L++ G
Sbjct: 300 VLENFHSDVFISILGQHWPEFSDVVQRQAIRDAIISTDMALHEQYLLKLRS-------CG 352
Query: 197 SGVLLLDNYTDRIQVLENLV-HCADLSNPTKPLPLYKRWVALLMEEF 334
+ L D I +L +L+ AD+SN ++PL + +W L+ EF
Sbjct: 353 TRSLRED-----IPLLTSLIIKAADISNVSRPLIISAQWAVLISYEF 394
>UniRef50_A5DVX9 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 638
Score = 35.9 bits (79), Expect = 0.60
Identities = 23/88 (26%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Frame = +2
Query: 74 EEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENL 253
EE + + +V +L+TDMS H L + ++ + + +I++L +L
Sbjct: 446 EESKLLIHDVVSATILATDMSNHFEYLHQVDSLSKEEDYGPCS-------DRKIKLLGSL 498
Query: 254 V-HCADLSNPTKPLPLYKRWVALLMEEF 334
+ AD+SN +PL + +W +L EF
Sbjct: 499 LLKAADISNVARPLKISCQWAVVLQREF 526
>UniRef50_Q4DJ46 Cluster: Putative uncharacterized protein; n=2;
Trypanosoma cruzi|Rep: Putative uncharacterized protein
- Trypanosoma cruzi
Length = 754
Score = 35.5 bits (78), Expect = 0.80
Identities = 28/113 (24%), Positives = 54/113 (47%), Gaps = 3/113 (2%)
Frame = +2
Query: 77 EQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLV 256
E+ L +M +++STD +H LL L+ ++ G+G ++ +++ + +L+N++
Sbjct: 482 EKGVELYEMTAQLIISTDERRHQVLLNQLQQILRE----GAGNVVRESHL--MIILQNVL 535
Query: 257 HCADLSNPTKPLPLYKRWVALLMEEFFQQGDRE---REHGMDISPMCDRHNAT 406
H AD + +Y+ A + E +QQ E G+ P H AT
Sbjct: 536 HAADFCYVFRLSSVYRIAAACAVAEVYQQNQTRIWLTERGLRQWPWNGPHAAT 588
>UniRef50_Q6FM93 Cluster: Similar to sp|P06776 Saccharomyces
cerevisiae YOR360c PDE2 high affinity 3; n=1; Candida
glabrata|Rep: Similar to sp|P06776 Saccharomyces
cerevisiae YOR360c PDE2 high affinity 3 - Candida
glabrata (Yeast) (Torulopsis glabrata)
Length = 575
Score = 35.1 bits (77), Expect = 1.1
Identities = 22/92 (23%), Positives = 47/92 (51%)
Frame = +2
Query: 59 VNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQ 238
+N +++ ++ ++ + +L+TDM+ H + L +++ + LL T
Sbjct: 374 INENDDNDKKMTINVITNAILATDMAMHAKYVDKLDELLKVPQH------LLPLPT---- 423
Query: 239 VLENLVHCADLSNPTKPLPLYKRWVALLMEEF 334
++ ++ AD+SN T+PL + RW L+ EF
Sbjct: 424 LIAVIIKAADISNVTRPLSISARWAFLITLEF 455
>UniRef50_Q5K8K8 Cluster: Mitochondrion protein, putative; n=2;
Filobasidiella neoformans|Rep: Mitochondrion protein,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 725
Score = 34.7 bits (76), Expect = 1.4
Identities = 25/84 (29%), Positives = 45/84 (53%), Gaps = 2/84 (2%)
Frame = +2
Query: 74 EEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENL 253
E+QRQ++ + + + V+S + L +KT VET++ G + LD+ T ++ LE +
Sbjct: 470 EQQRQSIEQRLREEVVSQGIELQRRWLRSIKTQVETER--GGRLAKLDSLTTSLKQLERI 527
Query: 254 V--HCADLSNPTKPLPLYKRWVAL 319
+ A L + + L+K W AL
Sbjct: 528 TLDNSATLDDNVR---LHKIWSAL 548
>UniRef50_A2FDY7 Cluster: Putative uncharacterized protein; n=1;
Trichomonas vaginalis G3|Rep: Putative uncharacterized
protein - Trichomonas vaginalis G3
Length = 151
Score = 34.3 bits (75), Expect = 1.8
Identities = 19/72 (26%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
Frame = +3
Query: 309 GWHY*WKSSSSKAIVNVNMAWISVQCVTDIMLL*KNLKSVSLTISCILCGKLGQIWYIL- 485
GW WK+ S ++ + A + + C+ ++++ KS +L + C++C + Q++YI+
Sbjct: 75 GWKKQWKNIKS-SVPCLIAAIVVIVCILLLLIVGIITKSKALCVICVICQWVAQVFYIIC 133
Query: 486 TLKIFWTP*KKT 521
+ WT K T
Sbjct: 134 SFPGGWTAIKTT 145
>UniRef50_Q4RHZ1 Cluster: Chromosome 8 SCAF15044, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 8 SCAF15044, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 884
Score = 33.9 bits (74), Expect = 2.4
Identities = 15/31 (48%), Positives = 20/31 (64%)
Frame = +2
Query: 266 DLSNPTKPLPLYKRWVALLMEEFFQQGDRER 358
DL T+P + K+ L+ EFF+QGDRER
Sbjct: 748 DLGAVTRPWKISKQVAELVTSEFFEQGDRER 778
>UniRef50_A5N7K8 Cluster: Response regulator-related protein; n=2;
Clostridium|Rep: Response regulator-related protein -
Clostridium kluyveri DSM 555
Length = 759
Score = 33.9 bits (74), Expect = 2.4
Identities = 23/96 (23%), Positives = 52/96 (54%), Gaps = 7/96 (7%)
Frame = +2
Query: 125 TDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRI---QVLENLVHCADLSNPTKPL- 292
TD+ K ++ D+K M+ +KV + V + Y +I Q +E ++ ++ + K L
Sbjct: 503 TDLHKARQIINDIKGMLLKEKVNSAYVDVSFGYECKISNEQKIEEVLKKSEDNMYKKKLF 562
Query: 293 --PLY-KRWVALLMEEFFQQGDREREHGMDISPMCD 391
P+ K+ +A +++ +++ +RE +H +S +C+
Sbjct: 563 ESPIMRKKTLASIIKALYERNEREEQHAQKVSELCE 598
>UniRef50_A0YKX3 Cluster: Sensor protein; n=1; Lyngbya sp. PCC
8106|Rep: Sensor protein - Lyngbya sp. PCC 8106
Length = 947
Score = 33.9 bits (74), Expect = 2.4
Identities = 13/39 (33%), Positives = 26/39 (66%), Gaps = 1/39 (2%)
Frame = +2
Query: 413 KSQVGFIDYIVHPLWETWADLVHPDAQD-ILDTLEENRD 526
K+ +G+ D+ + +E W +HPD +D +LDT++++ D
Sbjct: 182 KADLGYKDHELESNFEAWRSRIHPDDRDRVLDTVQKHLD 220
>UniRef50_A4C531 Cluster: Sensory box protein; n=1;
Pseudoalteromonas tunicata D2|Rep: Sensory box protein -
Pseudoalteromonas tunicata D2
Length = 725
Score = 33.5 bits (73), Expect = 3.2
Identities = 12/33 (36%), Positives = 19/33 (57%)
Frame = +2
Query: 422 VGFIDYIVHPLWETWADLVHPDAQDILDTLEEN 520
+GF + + W +W D +HPD DI +T +N
Sbjct: 197 LGFDNLLFGTSWSSWTDQIHPDDLDIFETQLQN 229
>UniRef50_Q9NHN7 Cluster: Septin interacting protein; n=12;
Diptera|Rep: Septin interacting protein - Drosophila
melanogaster (Fruit fly)
Length = 839
Score = 33.5 bits (73), Expect = 3.2
Identities = 17/42 (40%), Positives = 23/42 (54%)
Frame = +2
Query: 251 LVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
LV L NPT+PLPL K+W +L QQGD + ++
Sbjct: 455 LVQWQPLENPTEPLPLIKKWRGML-----QQGDAAEQQPRNV 491
>UniRef50_Q5BVJ4 Cluster: SJCHGC04836 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC04836 protein - Schistosoma
japonicum (Blood fluke)
Length = 198
Score = 33.5 bits (73), Expect = 3.2
Identities = 22/56 (39%), Positives = 24/56 (42%)
Frame = -2
Query: 414 FSIVALCLSHIGLISMPCSRSRSPCWKNSSISNATHRLYSGNGLVGLLRSAQCTRF 247
FS +CLS I LIS PC S S +SS H L N L G C F
Sbjct: 128 FSYCGVCLSSINLISDPCINSHSNESSDSSQHQTNHHLVHIN-LAGRHYHISCANF 182
>UniRef50_A2E1P4 Cluster: Beige/BEACH domain containing protein; n=1;
Trichomonas vaginalis G3|Rep: Beige/BEACH domain
containing protein - Trichomonas vaginalis G3
Length = 2423
Score = 33.1 bits (72), Expect = 4.3
Identities = 16/44 (36%), Positives = 25/44 (56%)
Frame = +2
Query: 53 IFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETK 184
+F N H + + ++K VID V+STD+ LL+ K + E K
Sbjct: 2043 LFDNDHPQRNMEIVKKSVIDKVISTDLRAKSLLLSQSKLVGENK 2086
>UniRef50_Q6R988 Cluster: Putative uncharacterized protein orf186;
n=4; Zea mays|Rep: Putative uncharacterized protein
orf186 - Zea mays (Maize)
Length = 186
Score = 32.7 bits (71), Expect = 5.6
Identities = 15/52 (28%), Positives = 29/52 (55%)
Frame = -1
Query: 535 LVIVSVFF*GVQNILSVRMYQICPSFPQRMHDIVNETDLRFFYSSIMSVTHW 380
L+++ VF V +L ++ CP + R+ +++ T F+YSS+M+ W
Sbjct: 32 LILILVF---VSRMLVRALWPRCPVWAARVFTLLSVTTALFYYSSLMTTAEW 80
>UniRef50_A5BXR8 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 405
Score = 32.7 bits (71), Expect = 5.6
Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Frame = +2
Query: 68 HEEEQR-QTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVL 244
HE +QR QT + + +V S + K+M + L++MV + +G L+ DNYT L
Sbjct: 18 HEIQQREQTFQNSSLSVVYS--LVKYMKIKDRLRSMVLEIEDLSAGYLVSDNYTFTFWEL 75
Query: 245 ENLVHCADLSNPTKPLPL 298
L C + + + L L
Sbjct: 76 GGLAACYGMFSSIRELGL 93
>UniRef50_Q0E4Y6 Cluster: 16 kDa; n=1; Spodoptera frugiperda
ascovirus 1a|Rep: 16 kDa - Spodoptera frugiperda
ascovirus 1a
Length = 152
Score = 32.3 bits (70), Expect = 7.4
Identities = 24/75 (32%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
Frame = -2
Query: 402 ALCLSHIGLISMPCSRSRSPCWKN-SSISNATHRLYSGNGLVGLLRSAQCTRFSNT*ILS 226
++C S +++ CS + SP N SS SN+ HR+ S L+ S Q T S++ L
Sbjct: 46 SVCFSSTSSVALTCSSASSPAPVNSSSSSNSLHRVVS-EELLPSSSSLQSTSSSSSSSLQ 104
Query: 225 V*LSSNKTPLPATFF 181
SS +T +++F
Sbjct: 105 STSSSAETSSSSSYF 119
>UniRef50_A7MG03 Cluster: Putative uncharacterized protein; n=1;
Enterobacter sakazakii ATCC BAA-894|Rep: Putative
uncharacterized protein - Enterobacter sakazakii ATCC
BAA-894
Length = 85
Score = 32.3 bits (70), Expect = 7.4
Identities = 10/25 (40%), Positives = 19/25 (76%)
Frame = +2
Query: 470 DLVHPDAQDILDTLEENRDYYQSMI 544
D VHP+ + ++ +E+N +YYQS++
Sbjct: 24 DEVHPEVKSYIENIEDNLEYYQSLL 48
>UniRef50_A1GCI9 Cluster: Peptidase U61, LD-carboxypeptidase A; n=3;
Bacteria|Rep: Peptidase U61, LD-carboxypeptidase A -
Salinispora arenicola CNS205
Length = 396
Score = 32.3 bits (70), Expect = 7.4
Identities = 17/41 (41%), Positives = 22/41 (53%)
Frame = -3
Query: 194 PRLSSFRPSSSDPPADSCVSTYLSRGPCR*PFS*GSVFAPP 72
PR ++ RP S+ PPAD+ + SR P R P G PP
Sbjct: 39 PRTAATRPRSATPPADARRRSGRSRSPARLPRRRGYPVPPP 79
>UniRef50_A4RPY9 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 862
Score = 32.3 bits (70), Expect = 7.4
Identities = 16/47 (34%), Positives = 29/47 (61%)
Frame = +2
Query: 404 TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
++ K+Q+GF++ PL++ AD++ P Q +D LE N+ + MI
Sbjct: 557 SLSKAQLGFMNLFAIPLFQGVADIL-PAMQYCVDELEINKALFDQMI 602
>UniRef50_UPI00006CFB29 Cluster: hypothetical protein
TTHERM_00471770; n=1; Tetrahymena thermophila SB210|Rep:
hypothetical protein TTHERM_00471770 - Tetrahymena
thermophila SB210
Length = 560
Score = 31.9 bits (69), Expect = 9.8
Identities = 39/154 (25%), Positives = 70/154 (45%), Gaps = 1/154 (0%)
Frame = +2
Query: 53 IFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMS-LLADLKTMVETKKVAGSGVLLLDNYTD 229
I VNL EE+ + + + M +M+K S L DLK++V+ K SG LLL++ T
Sbjct: 359 IGVNLEEEKNKYQHKAQNL-MFEKHEMAKQFSEFLYDLKSVVDGKLEIFSGELLLNDVTQ 417
Query: 230 RIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATI 409
L + + +DL K +++ + + F + + E+ + D+ D H I
Sbjct: 418 NTIFLFDYLK-SDLQYTKK---IFETCQEINAKIFIMKKNVEKCNQKDLVESIDAHIKQI 473
Query: 410 EKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL 511
+ +Q + I + + + L Q ILD +
Sbjct: 474 QSTQFRLLRNIENSIVRVFISL-----QQILDCM 502
>UniRef50_A6TT22 Cluster: GerA spore germination protein; n=1;
Alkaliphilus metalliredigens QYMF|Rep: GerA spore
germination protein - Alkaliphilus metalliredigens QYMF
Length = 538
Score = 31.9 bits (69), Expect = 9.8
Identities = 15/55 (27%), Positives = 33/55 (60%)
Frame = +2
Query: 77 EQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQV 241
E+R L + D++ ST + ++ L D+ V+ + ++G+G++L+ NY + I +
Sbjct: 110 EERTYLSSHIDDLIESTLPNSNICFLQDVNEAVD-ELLSGNGIILIQNYANVISI 163
>UniRef50_Q7R1F8 Cluster: GLP_38_64512_71054; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_38_64512_71054 - Giardia lamblia ATCC
50803
Length = 2180
Score = 31.9 bits (69), Expect = 9.8
Identities = 25/90 (27%), Positives = 38/90 (42%)
Frame = -3
Query: 395 VCHTLD*YPCHVHVHDRLAGRTLPSVMPPIVYTVATA**DCSDRHSVRDSLILEFYQCSC 216
+C TLD Y ++ + R P + P + S + SV+ + I+ CSC
Sbjct: 892 ICSTLDCYNITLYASSVTSSRPGPVIAHPCFPQQCK---EVSHKVSVKITEIIPDSDCSC 948
Query: 215 LAIRHRYPRLSSFRPSSSDPPADSCVSTYL 126
+ + L +FR S P CVS YL
Sbjct: 949 VDLVLNSRTLYTFRLSGKAMPYLPCVSQYL 978
>UniRef50_Q4D8H9 Cluster: Hydrolase, alpha/beta fold family,
putative; n=3; Trypanosoma|Rep: Hydrolase, alpha/beta
fold family, putative - Trypanosoma cruzi
Length = 312
Score = 31.9 bits (69), Expect = 9.8
Identities = 27/112 (24%), Positives = 50/112 (44%)
Frame = +2
Query: 2 EFGTRVAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVET 181
EF R+A ++ DG I + E ++ + + D ST + +H+S + ++ VE
Sbjct: 187 EFKCRLALRMA-GDGYPIDRDKQREFMKKIIERAPDD---STSLRRHLSAVQRAESRVEG 242
Query: 182 KKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFF 337
+ + L++ DR+ EN + A L + L L+ + EE F
Sbjct: 243 LRGLKTPTLVIHGMLDRLVPYENGIEIAKLIGRSAKLVLFPLMGHSIPEELF 294
>UniRef50_Q6CY30 Cluster: Similar to sp|P06776 Saccharomyces
cerevisiae YOR360c PDE2 high affinity 3; n=1;
Kluyveromyces lactis|Rep: Similar to sp|P06776
Saccharomyces cerevisiae YOR360c PDE2 high affinity 3 -
Kluyveromyces lactis (Yeast) (Candida sphaerica)
Length = 516
Score = 31.9 bits (69), Expect = 9.8
Identities = 12/28 (42%), Positives = 19/28 (67%)
Frame = +2
Query: 251 LVHCADLSNPTKPLPLYKRWVALLMEEF 334
++ AD+SN T+PL + +W AL+ EF
Sbjct: 392 IIKAADISNVTRPLLISAKWAALISMEF 419
>UniRef50_Q58073 Cluster: Uncharacterized protein MJ0659; n=1;
Methanocaldococcus jannaschii|Rep: Uncharacterized
protein MJ0659 - Methanococcus jannaschii
Length = 138
Score = 31.9 bits (69), Expect = 9.8
Identities = 20/84 (23%), Positives = 44/84 (52%), Gaps = 5/84 (5%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQR-----QTLRKMVIDMVLSTDMSKHMSLLADLKTMVET 181
+A L++ CD V + E+ + LRK+ I + + ++ K M+L+ +KT +
Sbjct: 33 IALTLIEKGYCDEAVKVAEKISSFGLKDEVLRKVAIAYIENGEIDKAMALVEKIKTETDL 92
Query: 182 KKVAGSGVLLLDNYTDRIQVLENL 253
+K+A ++ + Y + ++V E +
Sbjct: 93 EKIA-MKLIEIKKYREALKVAEKI 115
>UniRef50_P06776 Cluster: 3',5'-cyclic-nucleotide phosphodiesterase
2; n=2; Saccharomyces cerevisiae|Rep:
3',5'-cyclic-nucleotide phosphodiesterase 2 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 526
Score = 31.9 bits (69), Expect = 9.8
Identities = 14/43 (32%), Positives = 25/43 (58%)
Frame = +2
Query: 206 LLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEF 334
L+ +N +I ++ ++ AD+SN T+ L + RW L+ EF
Sbjct: 380 LMHENPMKQITLISLIIKAADISNVTRTLSISARWAYLITLEF 422
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 577,633,218
Number of Sequences: 1657284
Number of extensions: 11827979
Number of successful extensions: 36330
Number of sequences better than 10.0: 209
Number of HSP's better than 10.0 without gapping: 35038
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 36146
length of database: 575,637,011
effective HSP length: 96
effective length of database: 416,537,747
effective search space used: 34989170748
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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