Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= P5PG0343
(544 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U50159-1|AAA97892.1| 673|Homo sapiens cAMP-specific phoshodiest... 310 2e-84
U50158-1|AAA97891.1| 507|Homo sapiens cAMP-specific phosphodies... 310 2e-84
U50157-1|AAA97890.1| 585|Homo sapiens cAMP-specific phosphodies... 310 2e-84
L20970-1|AAA03592.1| 673|Homo sapiens phosphodiesterase protein. 310 2e-84
L20969-1|AAC00042.1| 809|Homo sapiens cyclic AMP phosphodiester... 310 2e-84
BC036319-1|AAH36319.1| 518|Homo sapiens PDE4D protein protein. 310 2e-84
AY388960-1|AAQ90404.1| 679|Homo sapiens cAMP-specific phosphodi... 310 2e-84
AY245867-1|AAP75761.1| 679|Homo sapiens cAMP-specific phosphodi... 310 2e-84
AY245866-1|AAP75760.1| 748|Homo sapiens cAMP-specific phosphodi... 310 2e-84
AF536976-1|AAN10118.1| 748|Homo sapiens cAMP-specific phosphodi... 310 2e-84
AF536975-1|AAN10117.1| 518|Homo sapiens cAMP-specific phosphodi... 310 2e-84
AF012074-1|AAC00070.1| 507|Homo sapiens cAMP-specific phosphodi... 310 2e-84
AF012073-1|AAC00069.1| 745|Homo sapiens cAMP-specific phosphodi... 310 2e-84
U85048-1|AAB96381.1| 721|Homo sapiens cyclic AMP specific phosp... 309 4e-84
U02882-1|AAC13745.1| 604|Homo sapiens 3',5'-cyclic AMP phosphod... 309 4e-84
M97515-1|AAA36426.1| 564|Homo sapiens phosphodiesterase protein. 309 4e-84
L20971-1|AAA03593.1| 564|Homo sapiens phosphodiesterase protein. 309 4e-84
L20966-1|AAA03589.1| 736|Homo sapiens phosphodiesterase protein. 309 4e-84
L12686-1|AAA35643.1| 606|Homo sapiens 3',5'-cyclic AMP phosphod... 309 4e-84
EF595686-1|ABQ85407.1| 503|Homo sapiens cAMP-specific phosphodi... 309 4e-84
BC105040-1|AAI05041.1| 736|Homo sapiens phosphodiesterase 4B, c... 309 4e-84
BC101480-1|AAI01481.1| 736|Homo sapiens phosphodiesterase 4B, c... 309 4e-84
AL592285-3|CAH70628.1| 721|Homo sapiens phosphodiesterase 4B, c... 309 4e-84
AL592285-1|CAH70626.1| 736|Homo sapiens phosphodiesterase 4B, c... 309 4e-84
AL359701-3|CAI23101.1| 721|Homo sapiens phosphodiesterase 4B, c... 309 4e-84
AL359701-2|CAI23100.1| 564|Homo sapiens phosphodiesterase 4B, c... 309 4e-84
AL359701-1|CAI23099.1| 736|Homo sapiens phosphodiesterase 4B, c... 309 4e-84
AL357273-3|CAH73004.1| 721|Homo sapiens phosphodiesterase 4B, c... 309 4e-84
AL357273-1|CAH73002.1| 736|Homo sapiens phosphodiesterase 4B, c... 309 4e-84
AL109926-4|CAI21751.1| 721|Homo sapiens phosphodiesterase 4B, c... 309 4e-84
AL109926-3|CAI21750.1| 564|Homo sapiens phosphodiesterase 4B, c... 309 4e-84
AL109926-2|CAI21749.1| 736|Homo sapiens phosphodiesterase 4B, c... 309 4e-84
AB209081-1|BAD92318.1| 726|Homo sapiens phosphodiesterase 4B, c... 309 4e-84
AF536977-1|AAN10119.1| 687|Homo sapiens cAMP-specific phosphodi... 307 1e-83
U97584-1|AAC25679.1| 647|Homo sapiens cyclic AMP-specific phosp... 307 2e-83
U68532-1|AAC63832.1| 647|Homo sapiens cyclic AMP specific phosp... 307 2e-83
U18087-1|AAC50458.1| 686|Homo sapiens 3',5'-cyclic AMP phosphod... 307 2e-83
S75213-1|AAB33798.1| 667|Homo sapiens type-IVA cyclic AMP speci... 307 2e-83
M37744-1|AAA69697.1| 775|Homo sapiens protein ( Human cyclic AM... 307 2e-83
L20965-1|AAA03588.1| 886|Homo sapiens phosphodiesterase protein. 307 2e-83
BC038234-1|AAH38234.1| 647|Homo sapiens phosphodiesterase 4A, c... 307 2e-83
BC019864-1|AAH19864.1| 647|Homo sapiens phosphodiesterase 4A, c... 307 2e-83
AY618547-1|AAU82096.1| 860|Homo sapiens cyclic AMP phosphodiest... 307 2e-83
AY593872-1|AAT00628.1| 864|Homo sapiens cAMP-specific phosphodi... 307 2e-83
AF073745-1|AAD34217.2| 825|Homo sapiens cyclic AMP-specific pho... 307 2e-83
AF069491-3|AAC35013.1| 647|Homo sapiens cAMP specific phosphodi... 307 2e-83
AF069491-2|AAC35015.1| 860|Homo sapiens putative novel cAMP spe... 307 2e-83
AF069491-1|AAC35012.1| 886|Homo sapiens cAMP specific phosphodi... 307 2e-83
Z46632-1|CAA86601.1| 712|Homo sapiens 3',5'-cyclic AMP phosphod... 302 4e-82
U88713-1|AAC51916.1| 700|Homo sapiens phosphodiesterase 4C prot... 302 4e-82
U88712-1|AAC51915.1| 606|Homo sapiens phosphodiesterase 4C prot... 302 4e-82
U66349-1|AAB96878.1| 427|Homo sapiens PDE4C-delta109 protein. 302 4e-82
U66348-1|AAB96877.1| 518|Homo sapiens PDE4C-delta54 protein. 302 4e-82
U66347-1|AAB96876.1| 426|Homo sapiens PDE4C-426 protein. 302 4e-82
U66346-1|AAB96875.1| 791|Homo sapiens PDE4C-791 protein. 302 4e-82
L20968-1|AAA03591.1| 251|Homo sapiens phosphodiesterase protein. 302 4e-82
BC109068-1|AAI09069.1| 549|Homo sapiens PDE4C protein protein. 302 4e-82
BC109067-1|AAI09068.1| 481|Homo sapiens PDE4C protein protein. 302 4e-82
AF157816-3|AAD47055.1| 606|Homo sapiens cAMP specific phosphodi... 302 4e-82
AF157816-2|AAD47054.1| 680|Homo sapiens cAMP specific phosphodi... 302 4e-82
AF157816-1|AAD47053.1| 712|Homo sapiens cAMP specific phosphodi... 302 4e-82
AC005759-5|AAC83049.1| 426|Homo sapiens PDE4C-426 protein. 302 4e-82
AC005759-4|AAC83048.1| 427|Homo sapiens PDE4C-delta109 protein. 302 4e-82
AC005759-3|AAC83051.1| 518|Homo sapiens PDE4C-delta54 protein. 302 4e-82
AC005759-2|AAC83047.1| 710|Homo sapiens CN4C_HUMAN protein. 302 4e-82
AC005759-1|AAC83050.1| 782|Homo sapiens PDE4C-791 protein. 302 4e-82
U18088-1|AAA98540.1| 323|Homo sapiens 3',5'-cyclic AMP phosphod... 226 3e-59
AF069491-4|AAC35014.1| 323|Homo sapiens cAMP specific phosphodi... 226 3e-59
AY266362-1|AAP31234.1| 102|Homo sapiens phosphodiesterase isozy... 190 2e-48
U86078-1|AAC51872.1| 536|Homo sapiens calmodulin-stimulated pho... 125 9e-29
U56976-1|AAC50769.1| 536|Homo sapiens calmodulin dependent phos... 125 9e-29
BX538092-1|CAD98011.1| 399|Homo sapiens hypothetical protein pr... 125 9e-29
BC032226-1|AAH32226.1| 536|Homo sapiens phosphodiesterase 1B, c... 125 9e-29
AJ401609-1|CAC82207.1| 516|Homo sapiens 3'5' cyclic nucleotide ... 125 9e-29
U40370-1|AAC50436.1| 535|Homo sapiens 3',5' cyclic nucleotide p... 119 8e-27
BC022480-1|AAH22480.1| 545|Homo sapiens phosphodiesterase 1A, c... 119 8e-27
AL110263-1|CAB53703.1| 519|Homo sapiens hypothetical protein pr... 119 8e-27
AJ401610-1|CAC82208.1| 519|Homo sapiens 3'5' cyclic nucleotide ... 119 8e-27
AB038224-9|BAB20054.1| 518|Homo sapiens calmodulin-dependent ph... 119 8e-27
AB038224-8|BAB20053.1| 501|Homo sapiens calmodulin-dependent ph... 119 8e-27
AB038224-7|BAB20057.1| 511|Homo sapiens calmodulin-dependent ph... 119 8e-27
AB038224-6|BAB20052.1| 552|Homo sapiens calmodulin-dependent ph... 119 8e-27
AB038224-5|BAB20050.1| 535|Homo sapiens calmodulin-dependent ph... 119 8e-27
AB038224-4|BAB20056.1| 545|Homo sapiens calmodulin-dependent ph... 119 8e-27
AB038224-3|BAB20051.1| 536|Homo sapiens calmodulin-dependent ph... 119 8e-27
AB038224-2|BAB20049.1| 519|Homo sapiens calmodulin-dependent ph... 119 8e-27
AB038224-1|BAB20055.1| 529|Homo sapiens calmodulin-dependent ph... 119 8e-27
U40372-1|AAA96961.1| 564|Homo sapiens PDE1C3 protein. 116 4e-26
U40371-1|AAC50437.1| 634|Homo sapiens 3',5' cyclic nucleotide p... 116 4e-26
BC022525-1|AAH22525.1| 634|Homo sapiens PDE1C protein protein. 116 4e-26
BC022479-1|AAH22479.1| 634|Homo sapiens PDE1C protein protein. 116 4e-26
AK091734-1|BAC03734.1| 769|Homo sapiens (EC 3.1.4.17). protein. 116 4e-26
AC006377-1|AAS07516.1| 591|Homo sapiens unknown protein. 116 4e-26
BC075822-1|AAH75822.1| 829|Homo sapiens phosphodiesterase 8A pr... 108 1e-23
BC060762-1|AAH60762.1| 829|Homo sapiens phosphodiesterase 8A pr... 108 1e-23
BC048317-1|AAH48317.1| 305|Homo sapiens PDE8A protein protein. 108 1e-23
AF388187-1|AAL18614.1| 582|Homo sapiens cAMP phosphodiesterase ... 108 1e-23
AF388186-1|AAL18613.1| 582|Homo sapiens cAMP phosphodiesterase ... 108 1e-23
AF388185-1|AAL18612.1| 449|Homo sapiens cAMP phosphodiesterase ... 108 1e-23
AF388184-1|AAL18611.1| 783|Homo sapiens cAMP phosphodiesterase ... 108 1e-23
AF388183-1|AAL18610.1| 829|Homo sapiens cAMP phosphodiesterase ... 108 1e-23
AF332653-1|AAK57641.1| 829|Homo sapiens cAMP-specific cyclic nu... 108 1e-23
AF056490-1|AAC39763.1| 713|Homo sapiens cAMP-specific phosphodi... 108 1e-23
BT007016-1|AAP35662.1| 533|Homo sapiens phosphodiesterase 9A pr... 105 8e-23
BC009047-1|AAH09047.1| 533|Homo sapiens phosphodiesterase 9A pr... 105 8e-23
AY701187-1|AAV84271.1| 485|Homo sapiens phosphodiesterase PDE9A... 105 8e-23
AY242121-1|AAO88210.1| 492|Homo sapiens type 9 cGMP-specific ph... 105 8e-23
AY196314-1|AAO34700.1| 386|Homo sapiens phosphodiesterase PDE9A... 105 8e-23
AY196313-1|AAO34699.1| 386|Homo sapiens phosphodiesterase PDE9A... 105 8e-23
AY196312-1|AAO34698.1| 567|Homo sapiens phosphodiesterase PDE9A... 105 8e-23
AY196311-1|AAO34697.1| 552|Homo sapiens phosphodiesterase PDE9A... 105 8e-23
AY196310-1|AAO34696.1| 526|Homo sapiens phosphodiesterase PDE9A... 105 8e-23
AY196309-1|AAO34695.1| 376|Homo sapiens phosphodiesterase PDE9A... 105 8e-23
AY196308-1|AAO34694.1| 386|Homo sapiens phosphodiesterase PDE9A... 105 8e-23
AY196307-1|AAO34693.1| 491|Homo sapiens phosphodiesterase PDE9A... 105 8e-23
AY196306-1|AAO34692.1| 459|Homo sapiens phosphodiesterase PDE9A... 105 8e-23
AY196305-1|AAO34691.1| 376|Homo sapiens phosphodiesterase PDE9A... 105 8e-23
AY196304-1|AAO34690.1| 433|Homo sapiens phosphodiesterase PDE9A... 105 8e-23
AY196303-1|AAO34689.1| 507|Homo sapiens phosphodiesterase PDE9A... 105 8e-23
AY196302-1|AAO34688.1| 386|Homo sapiens phosphodiesterase PDE9A... 105 8e-23
AY196301-1|AAO34687.1| 386|Homo sapiens phosphodiesterase PDE9A... 105 8e-23
AY196300-1|AAO34686.1| 492|Homo sapiens phosphodiesterase PDE9A... 105 8e-23
AY196299-1|AAO34685.1| 540|Homo sapiens phosphodiesterase PDE9A... 105 8e-23
AP001747-1|BAA95552.1| 593|Homo sapiens CGMP-specific 3',5'-cyc... 105 8e-23
AF067226-1|AAC26726.1| 465|Homo sapiens cGMP phosphodiesterase ... 105 8e-23
AF067225-1|AAC26725.1| 466|Homo sapiens cGMP phosphodiesterase ... 105 8e-23
AF067224-1|AAC26724.1| 533|Homo sapiens cGMP phosphodiesterase ... 105 8e-23
AF067223-1|AAC26723.1| 593|Homo sapiens cGMP phosphodiesterase ... 105 8e-23
AF048837-1|AAC39778.1| 593|Homo sapiens cGMP-specific phosphodi... 105 8e-23
AB017602-1|BAA88847.1| 593|Homo sapiens cGMP phosphodiesterase ... 105 8e-23
BC035144-1|AAH35144.1| 385|Homo sapiens PDE8B protein protein. 101 2e-21
BC047627-1|AAH47627.1| 241|Homo sapiens PDE8B protein protein. 100 3e-21
AY423729-1|AAS00492.1| 350|Homo sapiens proliferation-inducing ... 100 3e-21
AY129950-3|AAN71727.1| 788|Homo sapiens cAMP-specific phosphodi... 100 3e-21
AY129950-2|AAN71726.1| 838|Homo sapiens cAMP-specific phosphodi... 100 3e-21
AY129950-1|AAN71725.1| 885|Homo sapiens cAMP-specific phosphodi... 100 3e-21
AY129949-1|AAN71724.1| 788|Homo sapiens cAMP-specific phosphodi... 100 3e-21
AY129948-1|AAN71723.1| 838|Homo sapiens cAMP-specific phosphodi... 100 3e-21
AL831924-1|CAD38584.1| 843|Homo sapiens hypothetical protein pr... 100 3e-21
AF079529-1|AAC69564.2| 885|Homo sapiens cAMP-specific phosphodi... 100 3e-21
AB085827-1|BAC53765.1| 865|Homo sapiens phosphodiesterase 8B4 p... 100 3e-21
AB085826-1|BAC53764.1| 830|Homo sapiens phosphodiesterase 8B3 p... 100 3e-21
AB085825-1|BAC53763.1| 788|Homo sapiens phosphodiestearse 8B2 p... 100 3e-21
AB085824-1|BAC53762.1| 885|Homo sapiens phosphodiesterase 8B1 p... 100 3e-21
AL109778-1|CAB52432.1| 178|Homo sapiens PDE8A; phosphodiesteras... 97 3e-20
U67932-1|AAB65772.1| 456|Homo sapiens cAMP phosphodiesterase PD... 97 5e-20
L12052-1|AAA35644.2| 482|Homo sapiens cAMP phosphodiesterase PD... 97 5e-20
BC126360-1|AAI26361.1| 456|Homo sapiens phosphodiesterase 7A pr... 97 5e-20
EF108327-1|ABL14249.1| 502|Homo sapiens phosphodiesterase PDE7B... 91 3e-18
BC075083-1|AAH75083.1| 450|Homo sapiens phosphodiesterase 7B pr... 91 3e-18
BC075082-1|AAH75082.1| 450|Homo sapiens phosphodiesterase 7B pr... 91 3e-18
AL360178-1|CAH73075.1| 450|Homo sapiens phosphodiesterase 7B pr... 91 3e-18
AL138828-4|CAI95287.1| 450|Homo sapiens phosphodiesterase 7B pr... 91 3e-18
AL133319-1|CAH73332.1| 450|Homo sapiens phosphodiesterase 7B pr... 91 3e-18
AJ251860-1|CAB92441.1| 450|Homo sapiens phosphodiesterase 7B pr... 91 3e-18
AB209990-1|BAE06072.1| 586|Homo sapiens PDE7B variant protein p... 91 3e-18
AB038040-1|BAA96537.1| 450|Homo sapiens cyclic nucleotide phosp... 91 3e-18
AK127365-1|BAC86945.1| 129|Homo sapiens protein ( Homo sapiens ... 89 7e-18
AC068499-2|AAF67386.1| 115|Homo sapiens PDE4C [amino acids 597-... 86 7e-17
AL109687-1|CAB52020.1| 160|Homo sapiens PDE8A; phosphodiesteras... 85 2e-16
X95520-1|CAA64774.1| 1112|Homo sapiens cyclic nucleotide phospho... 82 1e-15
U38178-1|AAC50724.1| 1112|Homo sapiens cyclic nucleotide phophod... 82 1e-15
D50640-1|BAA09306.1| 1112|Homo sapiens phosphodiesterase 3B prot... 82 1e-15
BC150307-1|AAI50308.1| 1112|Homo sapiens phosphodiesterase 3B, c... 82 1e-15
AY459346-1|AAR24292.1| 1112|Homo sapiens cGMP-inhibited cAMP pho... 82 1e-15
AF332652-1|AAK57640.1| 424|Homo sapiens cAMP-specific cyclic nu... 81 3e-15
U67733-1|AAC51320.1| 941|Homo sapiens PDE2A3 protein. 79 1e-14
AY495087-1|AAS75513.1| 932|Homo sapiens cGMP-stimulated phospho... 79 1e-14
AK131525-1|BAD18664.1| 685|Homo sapiens protein ( Homo sapiens ... 79 1e-14
BC040974-1|AAH40974.1| 941|Homo sapiens phosphodiesterase 2A, c... 76 9e-14
U36798-1|AAB18673.1| 1141|Homo sapiens platelet cGI-PDE protein. 73 5e-13
M91667-1|AAA35912.2| 1141|Homo sapiens cGMP-inhibited cAMP phosp... 73 5e-13
BC117371-1|AAI17372.1| 1141|Homo sapiens phosphodiesterase 3A, c... 73 5e-13
BC117369-1|AAI17370.1| 1141|Homo sapiens phosphodiesterase 3A, c... 73 5e-13
AJ005036-1|CAA06304.1| 1141|Homo sapiens phosphodiesterase 3A pr... 73 5e-13
D89094-1|BAA28945.1| 875|Homo sapiens 3',5'-cyclic GMP phosphod... 67 4e-11
BC126233-1|AAI26234.1| 875|Homo sapiens phosphodiesterase 5A, c... 67 4e-11
AY264918-1|AAP21809.1| 833|Homo sapiens phosphodiesterase 5A pr... 67 4e-11
AJ004865-1|CAA06170.1| 875|Homo sapiens cGMP-binding, cGMP-spec... 67 4e-11
AF043731-1|AAC63967.1| 875|Homo sapiens cGMP-binding cGMP-speci... 67 4e-11
AC093752-1|AAY40985.1| 331|Homo sapiens unknown protein. 67 4e-11
AB015656-1|BAA81667.1| 833|Homo sapiens cGMP-binding cGMP speci... 67 4e-11
AB001635-1|BAA33372.2| 875|Homo sapiens cGMP-binding cGMP-speci... 67 4e-11
CR536567-1|CAG38804.1| 779|Homo sapiens PDE10A protein. 64 2e-10
BC104860-1|AAI04861.1| 779|Homo sapiens phosphodiesterase 10A p... 64 4e-10
BC104858-1|AAI04859.1| 779|Homo sapiens phosphodiesterase 10A p... 64 4e-10
AL160160-1|CAH72023.1| 779|Homo sapiens phosphodiesterase 10A p... 64 4e-10
AL136130-1|CAI20436.1| 779|Homo sapiens phosphodiesterase 10A p... 64 4e-10
AL117345-1|CAB92797.2| 779|Homo sapiens phosphodiesterase 10A p... 64 4e-10
AF127480-1|AAD32596.1| 807|Homo sapiens 3',5'-cyclic nucleotide... 64 4e-10
AF127479-1|AAD32595.1| 779|Homo sapiens 3',5'-cyclic nucleotide... 64 4e-10
AB041798-3|BAB16383.1| 714|Homo sapiens phosphodiesterase 10A1 ... 64 4e-10
AB026816-1|BAA84467.1| 789|Homo sapiens 3',5'-cyclic nucleotide... 64 4e-10
AB020593-1|BAA78034.1| 779|Homo sapiens 3',5'-Cyclic nucleotide... 64 4e-10
X62692-1|CAA44569.1| 854|Homo sapiens cGMP phosphodiesterase be... 63 5e-10
M26061-1|AAB69155.1| 860|Homo sapiens PDEA protein. 62 9e-10
BC035909-1|AAH35909.1| 860|Homo sapiens phosphodiesterase 6A, c... 62 9e-10
X90587-1|CAA62215.1| 617|Homo sapiens Rod cGMP phosphodiesteras... 62 1e-09
X66142-1|CAA46932.1| 854|Homo sapiens 3',5'-cyclic-nucleotide ... 62 1e-09
S41458-1|AAB22690.1| 854|Homo sapiens rod cGMP phosphodiesteras... 62 1e-09
BT009794-1|AAP88796.1| 853|Homo sapiens phosphodiesterase 6B, c... 61 2e-09
BC000249-1|AAH00249.1| 853|Homo sapiens phosphodiesterase 6B, c... 61 2e-09
BC114431-1|AAI14432.1| 934|Homo sapiens phosphodiesterase 11A p... 61 3e-09
BC112393-1|AAI12394.1| 934|Homo sapiens phosphodiesterase 11A p... 61 3e-09
AJ278682-1|CAC15567.1| 684|Homo sapiens cAMP/cGMP cyclic nucleo... 61 3e-09
AJ251509-1|CAB82573.1| 490|Homo sapiens cyclic nucleotide phosp... 61 3e-09
AF281865-1|AAG32023.1| 576|Homo sapiens cAMP/cGMP phosphodieste... 61 3e-09
AB048423-3|BAB62714.1| 490|Homo sapiens phosphodiesterase 11A1 ... 61 3e-09
AB048423-2|BAB62712.1| 934|Homo sapiens phosphodiesterase 11A4 ... 61 3e-09
AB048423-1|BAB62713.2| 684|Homo sapiens phosphodiesterase 11A3 ... 61 3e-09
AB038041-1|BAB16372.1| 684|Homo sapiens phosphodiesterase 11A3 ... 61 3e-09
AB036704-1|BAB16371.1| 934|Homo sapiens phosphodiesterase 11A p... 61 3e-09
U40584-1|AAB50018.1| 184|Homo sapiens calcium/calmodulin-stimul... 60 4e-09
X94354-1|CAA64079.1| 858|Homo sapiens cone cGMP phosphodiestera... 55 1e-07
U31973-1|AAA96392.1| 858|Homo sapiens phosphodiesterase A' subu... 55 1e-07
U20212-1|AAA92886.1| 858|Homo sapiens cone photoreceptor cGMP-p... 55 1e-07
AL356214-7|CAH72330.1| 858|Homo sapiens phosphodiesterase 6C, c... 55 1e-07
AL157396-4|CAH73839.1| 858|Homo sapiens phosphodiesterase 6C, c... 55 1e-07
AC073834-2|AAX93113.1| 125|Homo sapiens unknown protein. 48 3e-05
M94539-1|AAA58405.1| 116|Homo sapiens cyclic nucleotide phospho... 40 0.006
AB000520-1|BAA22514.1| 632|Homo sapiens APS protein. 29 8.0
>U50159-1|AAA97892.1| 673|Homo sapiens cAMP-specific
phoshodiesterase HPDE4D3 variant protein.
Length = 673
Score = 310 bits (761), Expect = 2e-84
Identities = 141/176 (80%), Positives = 162/176 (92%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL ++QRQ+LRKMVID+VL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 402 VGFKLLQEENCDIFQNL-TKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTS 460
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNY+DRIQVL+N+VHCADLSNPTKPL LY++W +MEEFF+QGDRERE GM+I
Sbjct: 461 SGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEI 520
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+HNA++EKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE+NR++YQS I
Sbjct: 521 SPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTI 576
>U50158-1|AAA97891.1| 507|Homo sapiens cAMP-specific
phosphodiesterase HPDE4D2 variant protein.
Length = 507
Score = 310 bits (761), Expect = 2e-84
Identities = 141/176 (80%), Positives = 162/176 (92%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL ++QRQ+LRKMVID+VL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 236 VGFKLLQEENCDIFQNL-TKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTS 294
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNY+DRIQVL+N+VHCADLSNPTKPL LY++W +MEEFF+QGDRERE GM+I
Sbjct: 295 SGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEI 354
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+HNA++EKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE+NR++YQS I
Sbjct: 355 SPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTI 410
>U50157-1|AAA97890.1| 585|Homo sapiens cAMP-specific
phosphodiesterase HPDE4D1 variant protein.
Length = 585
Score = 310 bits (761), Expect = 2e-84
Identities = 141/176 (80%), Positives = 162/176 (92%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL ++QRQ+LRKMVID+VL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 314 VGFKLLQEENCDIFQNL-TKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTS 372
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNY+DRIQVL+N+VHCADLSNPTKPL LY++W +MEEFF+QGDRERE GM+I
Sbjct: 373 SGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEI 432
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+HNA++EKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE+NR++YQS I
Sbjct: 433 SPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTI 488
>L20970-1|AAA03592.1| 673|Homo sapiens phosphodiesterase protein.
Length = 673
Score = 310 bits (761), Expect = 2e-84
Identities = 141/176 (80%), Positives = 162/176 (92%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL ++QRQ+LRKMVID+VL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 402 VGFKLLQEENCDIFQNL-TKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTS 460
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNY+DRIQVL+N+VHCADLSNPTKPL LY++W +MEEFF+QGDRERE GM+I
Sbjct: 461 SGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEI 520
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+HNA++EKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE+NR++YQS I
Sbjct: 521 SPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTI 576
>L20969-1|AAC00042.1| 809|Homo sapiens cyclic AMP phosphodiesterase
protein.
Length = 809
Score = 310 bits (761), Expect = 2e-84
Identities = 141/176 (80%), Positives = 162/176 (92%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL ++QRQ+LRKMVID+VL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 538 VGFKLLQEENCDIFQNL-TKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTS 596
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNY+DRIQVL+N+VHCADLSNPTKPL LY++W +MEEFF+QGDRERE GM+I
Sbjct: 597 SGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEI 656
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+HNA++EKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE+NR++YQS I
Sbjct: 657 SPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTI 712
>BC036319-1|AAH36319.1| 518|Homo sapiens PDE4D protein protein.
Length = 518
Score = 310 bits (761), Expect = 2e-84
Identities = 141/176 (80%), Positives = 162/176 (92%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL ++QRQ+LRKMVID+VL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 247 VGFKLLQEENCDIFQNL-TKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTS 305
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNY+DRIQVL+N+VHCADLSNPTKPL LY++W +MEEFF+QGDRERE GM+I
Sbjct: 306 SGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEI 365
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+HNA++EKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE+NR++YQS I
Sbjct: 366 SPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTI 421
>AY388960-1|AAQ90404.1| 679|Homo sapiens cAMP-specific
phosphodiesterase PDE4D9 protein.
Length = 679
Score = 310 bits (761), Expect = 2e-84
Identities = 141/176 (80%), Positives = 162/176 (92%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL ++QRQ+LRKMVID+VL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 408 VGFKLLQEENCDIFQNL-TKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTS 466
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNY+DRIQVL+N+VHCADLSNPTKPL LY++W +MEEFF+QGDRERE GM+I
Sbjct: 467 SGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEI 526
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+HNA++EKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE+NR++YQS I
Sbjct: 527 SPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTI 582
>AY245867-1|AAP75761.1| 679|Homo sapiens cAMP-specific
phosphodiesterase variant PDE4D9 protein.
Length = 679
Score = 310 bits (761), Expect = 2e-84
Identities = 141/176 (80%), Positives = 162/176 (92%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL ++QRQ+LRKMVID+VL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 408 VGFKLLQEENCDIFQNL-TKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTS 466
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNY+DRIQVL+N+VHCADLSNPTKPL LY++W +MEEFF+QGDRERE GM+I
Sbjct: 467 SGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEI 526
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+HNA++EKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE+NR++YQS I
Sbjct: 527 SPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTI 582
>AY245866-1|AAP75760.1| 748|Homo sapiens cAMP-specific
phosphodiesterase variant PDE4D7 protein.
Length = 748
Score = 310 bits (761), Expect = 2e-84
Identities = 141/176 (80%), Positives = 162/176 (92%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL ++QRQ+LRKMVID+VL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 477 VGFKLLQEENCDIFQNL-TKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTS 535
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNY+DRIQVL+N+VHCADLSNPTKPL LY++W +MEEFF+QGDRERE GM+I
Sbjct: 536 SGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEI 595
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+HNA++EKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE+NR++YQS I
Sbjct: 596 SPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTI 651
>AF536976-1|AAN10118.1| 748|Homo sapiens cAMP-specific
phosphodiesterase PDE4D7 protein.
Length = 748
Score = 310 bits (761), Expect = 2e-84
Identities = 141/176 (80%), Positives = 162/176 (92%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL ++QRQ+LRKMVID+VL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 477 VGFKLLQEENCDIFQNL-TKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTS 535
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNY+DRIQVL+N+VHCADLSNPTKPL LY++W +MEEFF+QGDRERE GM+I
Sbjct: 536 SGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEI 595
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+HNA++EKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE+NR++YQS I
Sbjct: 596 SPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTI 651
>AF536975-1|AAN10117.1| 518|Homo sapiens cAMP-specific
phosphodiesterase PDE4D6 protein.
Length = 518
Score = 310 bits (761), Expect = 2e-84
Identities = 141/176 (80%), Positives = 162/176 (92%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL ++QRQ+LRKMVID+VL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 247 VGFKLLQEENCDIFQNL-TKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTS 305
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNY+DRIQVL+N+VHCADLSNPTKPL LY++W +MEEFF+QGDRERE GM+I
Sbjct: 306 SGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEI 365
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+HNA++EKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE+NR++YQS I
Sbjct: 366 SPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTI 421
>AF012074-1|AAC00070.1| 507|Homo sapiens cAMP-specific
phosphodiesterase PDE4D2 protein.
Length = 507
Score = 310 bits (761), Expect = 2e-84
Identities = 141/176 (80%), Positives = 162/176 (92%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL ++QRQ+LRKMVID+VL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 236 VGFKLLQEENCDIFQNL-TKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTS 294
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNY+DRIQVL+N+VHCADLSNPTKPL LY++W +MEEFF+QGDRERE GM+I
Sbjct: 295 SGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEI 354
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+HNA++EKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE+NR++YQS I
Sbjct: 355 SPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTI 410
>AF012073-1|AAC00069.1| 745|Homo sapiens cAMP-specific
phosphodiesterase PDE4D5 protein.
Length = 745
Score = 310 bits (761), Expect = 2e-84
Identities = 141/176 (80%), Positives = 162/176 (92%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL ++QRQ+LRKMVID+VL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 474 VGFKLLQEENCDIFQNL-TKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTS 532
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNY+DRIQVL+N+VHCADLSNPTKPL LY++W +MEEFF+QGDRERE GM+I
Sbjct: 533 SGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEI 592
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+HNA++EKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE+NR++YQS I
Sbjct: 593 SPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTI 648
>U85048-1|AAB96381.1| 721|Homo sapiens cyclic AMP specific
phosphodiesterase protein.
Length = 721
Score = 309 bits (759), Expect = 4e-84
Identities = 143/176 (81%), Positives = 160/176 (90%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF+NL ++QRQTLRKMVIDMVL+TDMSKHMSLLADLKTMVETKKV
Sbjct: 467 VGFKLLQEEHCDIFMNL-TKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTS 525
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W +MEEFFQQGD+ERE GM+I
Sbjct: 526 SGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEI 585
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLV PDAQDILDTLE+NR++YQSMI
Sbjct: 586 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMI 641
>U02882-1|AAC13745.1| 604|Homo sapiens 3',5'-cyclic AMP
phosphodiesterase protein.
Length = 604
Score = 309 bits (759), Expect = 4e-84
Identities = 141/176 (80%), Positives = 161/176 (91%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL ++QRQ+LRKMVID+VL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 333 VGFKLLQEENCDIFQNL-TKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTS 391
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNY+DRIQVL+N+VHCADLSNPTKPL LY++W +MEEFF QGDRERE GM+I
Sbjct: 392 SGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFPQGDRERERGMEI 451
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+HNA++EKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE+NR++YQS I
Sbjct: 452 SPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTI 507
>M97515-1|AAA36426.1| 564|Homo sapiens phosphodiesterase protein.
Length = 564
Score = 309 bits (759), Expect = 4e-84
Identities = 143/176 (81%), Positives = 160/176 (90%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF+NL ++QRQTLRKMVIDMVL+TDMSKHMSLLADLKTMVETKKV
Sbjct: 310 VGFKLLQEEHCDIFMNL-TKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTS 368
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W +MEEFFQQGD+ERE GM+I
Sbjct: 369 SGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEI 428
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLV PDAQDILDTLE+NR++YQSMI
Sbjct: 429 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMI 484
>L20971-1|AAA03593.1| 564|Homo sapiens phosphodiesterase protein.
Length = 564
Score = 309 bits (759), Expect = 4e-84
Identities = 143/176 (81%), Positives = 160/176 (90%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF+NL ++QRQTLRKMVIDMVL+TDMSKHMSLLADLKTMVETKKV
Sbjct: 310 VGFKLLQEEHCDIFMNL-TKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTS 368
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W +MEEFFQQGD+ERE GM+I
Sbjct: 369 SGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEI 428
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLV PDAQDILDTLE+NR++YQSMI
Sbjct: 429 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMI 484
>L20966-1|AAA03589.1| 736|Homo sapiens phosphodiesterase protein.
Length = 736
Score = 309 bits (759), Expect = 4e-84
Identities = 143/176 (81%), Positives = 160/176 (90%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF+NL ++QRQTLRKMVIDMVL+TDMSKHMSLLADLKTMVETKKV
Sbjct: 482 VGFKLLQEEHCDIFMNL-TKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTS 540
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W +MEEFFQQGD+ERE GM+I
Sbjct: 541 SGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEI 600
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLV PDAQDILDTLE+NR++YQSMI
Sbjct: 601 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMI 656
>L12686-1|AAA35643.1| 606|Homo sapiens 3',5'-cyclic AMP
phosphodiesterase protein.
Length = 606
Score = 309 bits (759), Expect = 4e-84
Identities = 143/176 (81%), Positives = 160/176 (90%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF+NL ++QRQTLRKMVIDMVL+TDMSKHMSLLADLKTMVETKKV
Sbjct: 352 VGFKLLQEEHCDIFMNL-TKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTS 410
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W +MEEFFQQGD+ERE GM+I
Sbjct: 411 SGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEI 470
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLV PDAQDILDTLE+NR++YQSMI
Sbjct: 471 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMI 526
>EF595686-1|ABQ85407.1| 503|Homo sapiens cAMP-specific
phosphodiesterase-4 B isoform protein.
Length = 503
Score = 309 bits (759), Expect = 4e-84
Identities = 143/176 (81%), Positives = 160/176 (90%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF+NL ++QRQTLRKMVIDMVL+TDMSKHMSLLADLKTMVETKKV
Sbjct: 249 VGFKLLQEEHCDIFMNL-TKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTS 307
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W +MEEFFQQGD+ERE GM+I
Sbjct: 308 SGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEI 367
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLV PDAQDILDTLE+NR++YQSMI
Sbjct: 368 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMI 423
>BC105040-1|AAI05041.1| 736|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog, Drosop
protein.
Length = 736
Score = 309 bits (759), Expect = 4e-84
Identities = 143/176 (81%), Positives = 160/176 (90%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF+NL ++QRQTLRKMVIDMVL+TDMSKHMSLLADLKTMVETKKV
Sbjct: 482 VGFKLLQEEHCDIFMNL-TKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTS 540
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W +MEEFFQQGD+ERE GM+I
Sbjct: 541 SGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEI 600
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLV PDAQDILDTLE+NR++YQSMI
Sbjct: 601 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMI 656
>BC101480-1|AAI01481.1| 736|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog, Drosop
protein.
Length = 736
Score = 309 bits (759), Expect = 4e-84
Identities = 143/176 (81%), Positives = 160/176 (90%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF+NL ++QRQTLRKMVIDMVL+TDMSKHMSLLADLKTMVETKKV
Sbjct: 482 VGFKLLQEEHCDIFMNL-TKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTS 540
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W +MEEFFQQGD+ERE GM+I
Sbjct: 541 SGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEI 600
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLV PDAQDILDTLE+NR++YQSMI
Sbjct: 601 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMI 656
>AL592285-3|CAH70628.1| 721|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog,
Drosop protein.
Length = 721
Score = 309 bits (759), Expect = 4e-84
Identities = 143/176 (81%), Positives = 160/176 (90%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF+NL ++QRQTLRKMVIDMVL+TDMSKHMSLLADLKTMVETKKV
Sbjct: 467 VGFKLLQEEHCDIFMNL-TKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTS 525
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W +MEEFFQQGD+ERE GM+I
Sbjct: 526 SGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEI 585
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLV PDAQDILDTLE+NR++YQSMI
Sbjct: 586 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMI 641
>AL592285-1|CAH70626.1| 736|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog, Drosop
protein.
Length = 736
Score = 309 bits (759), Expect = 4e-84
Identities = 143/176 (81%), Positives = 160/176 (90%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF+NL ++QRQTLRKMVIDMVL+TDMSKHMSLLADLKTMVETKKV
Sbjct: 482 VGFKLLQEEHCDIFMNL-TKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTS 540
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W +MEEFFQQGD+ERE GM+I
Sbjct: 541 SGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEI 600
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLV PDAQDILDTLE+NR++YQSMI
Sbjct: 601 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMI 656
>AL359701-3|CAI23101.1| 721|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog,
Drosop protein.
Length = 721
Score = 309 bits (759), Expect = 4e-84
Identities = 143/176 (81%), Positives = 160/176 (90%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF+NL ++QRQTLRKMVIDMVL+TDMSKHMSLLADLKTMVETKKV
Sbjct: 467 VGFKLLQEEHCDIFMNL-TKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTS 525
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W +MEEFFQQGD+ERE GM+I
Sbjct: 526 SGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEI 585
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLV PDAQDILDTLE+NR++YQSMI
Sbjct: 586 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMI 641
>AL359701-2|CAI23100.1| 564|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog,
Drosop protein.
Length = 564
Score = 309 bits (759), Expect = 4e-84
Identities = 143/176 (81%), Positives = 160/176 (90%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF+NL ++QRQTLRKMVIDMVL+TDMSKHMSLLADLKTMVETKKV
Sbjct: 310 VGFKLLQEEHCDIFMNL-TKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTS 368
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W +MEEFFQQGD+ERE GM+I
Sbjct: 369 SGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEI 428
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLV PDAQDILDTLE+NR++YQSMI
Sbjct: 429 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMI 484
>AL359701-1|CAI23099.1| 736|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog, Drosop
protein.
Length = 736
Score = 309 bits (759), Expect = 4e-84
Identities = 143/176 (81%), Positives = 160/176 (90%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF+NL ++QRQTLRKMVIDMVL+TDMSKHMSLLADLKTMVETKKV
Sbjct: 482 VGFKLLQEEHCDIFMNL-TKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTS 540
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W +MEEFFQQGD+ERE GM+I
Sbjct: 541 SGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEI 600
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLV PDAQDILDTLE+NR++YQSMI
Sbjct: 601 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMI 656
>AL357273-3|CAH73004.1| 721|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog,
Drosop protein.
Length = 721
Score = 309 bits (759), Expect = 4e-84
Identities = 143/176 (81%), Positives = 160/176 (90%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF+NL ++QRQTLRKMVIDMVL+TDMSKHMSLLADLKTMVETKKV
Sbjct: 467 VGFKLLQEEHCDIFMNL-TKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTS 525
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W +MEEFFQQGD+ERE GM+I
Sbjct: 526 SGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEI 585
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLV PDAQDILDTLE+NR++YQSMI
Sbjct: 586 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMI 641
>AL357273-1|CAH73002.1| 736|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog, Drosop
protein.
Length = 736
Score = 309 bits (759), Expect = 4e-84
Identities = 143/176 (81%), Positives = 160/176 (90%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF+NL ++QRQTLRKMVIDMVL+TDMSKHMSLLADLKTMVETKKV
Sbjct: 482 VGFKLLQEEHCDIFMNL-TKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTS 540
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W +MEEFFQQGD+ERE GM+I
Sbjct: 541 SGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEI 600
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLV PDAQDILDTLE+NR++YQSMI
Sbjct: 601 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMI 656
>AL109926-4|CAI21751.1| 721|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog,
Drosop protein.
Length = 721
Score = 309 bits (759), Expect = 4e-84
Identities = 143/176 (81%), Positives = 160/176 (90%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF+NL ++QRQTLRKMVIDMVL+TDMSKHMSLLADLKTMVETKKV
Sbjct: 467 VGFKLLQEEHCDIFMNL-TKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTS 525
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W +MEEFFQQGD+ERE GM+I
Sbjct: 526 SGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEI 585
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLV PDAQDILDTLE+NR++YQSMI
Sbjct: 586 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMI 641
>AL109926-3|CAI21750.1| 564|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog,
Drosop protein.
Length = 564
Score = 309 bits (759), Expect = 4e-84
Identities = 143/176 (81%), Positives = 160/176 (90%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF+NL ++QRQTLRKMVIDMVL+TDMSKHMSLLADLKTMVETKKV
Sbjct: 310 VGFKLLQEEHCDIFMNL-TKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTS 368
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W +MEEFFQQGD+ERE GM+I
Sbjct: 369 SGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEI 428
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLV PDAQDILDTLE+NR++YQSMI
Sbjct: 429 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMI 484
>AL109926-2|CAI21749.1| 736|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog, Drosop
protein.
Length = 736
Score = 309 bits (759), Expect = 4e-84
Identities = 143/176 (81%), Positives = 160/176 (90%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF+NL ++QRQTLRKMVIDMVL+TDMSKHMSLLADLKTMVETKKV
Sbjct: 482 VGFKLLQEEHCDIFMNL-TKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTS 540
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W +MEEFFQQGD+ERE GM+I
Sbjct: 541 SGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEI 600
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLV PDAQDILDTLE+NR++YQSMI
Sbjct: 601 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMI 656
>AB209081-1|BAD92318.1| 726|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog,
Drosop protein.
Length = 726
Score = 309 bits (759), Expect = 4e-84
Identities = 143/176 (81%), Positives = 160/176 (90%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF+NL ++QRQTLRKMVIDMVL+TDMSKHMSLLADLKTMVETKKV
Sbjct: 472 VGFKLLQEEHCDIFMNL-TKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTS 530
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNYTDRIQVL N+VHCADLSNPTK L LY++W +MEEFFQQGD+ERE GM+I
Sbjct: 531 SGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEI 590
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLV PDAQDILDTLE+NR++YQSMI
Sbjct: 591 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMI 646
>AF536977-1|AAN10119.1| 687|Homo sapiens cAMP-specific
phosphodiesterase PDE4D8 protein.
Length = 687
Score = 307 bits (754), Expect = 1e-83
Identities = 140/176 (79%), Positives = 161/176 (91%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + C IF NL ++QRQ+LRKMVID+VL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 416 VGFKLLQEENCGIFQNL-TKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTS 474
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNY+DRIQVL+N+VHCADLSNPTKPL LY++W +MEEFF+QGDRERE GM+I
Sbjct: 475 SGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEI 534
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+HNA++EKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE+NR++YQS I
Sbjct: 535 SPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTI 590
>U97584-1|AAC25679.1| 647|Homo sapiens cyclic AMP-specific
phosphodiesterase HSPDE4A1A protein.
Length = 647
Score = 307 bits (753), Expect = 2e-83
Identities = 141/176 (80%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ D CDIF NL + QRQ+LRKMVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 270 VGFKLLQEDNCDIFQNL-SKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTS 328
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W +M EFFQQGDRERE GM+I
Sbjct: 329 SGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEI 388
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLVHPDAQ+ILDTLE+NRD+Y S I
Sbjct: 389 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI 444
>U68532-1|AAC63832.1| 647|Homo sapiens cyclic AMP specific
phosphodiesterase RD1 protein.
Length = 647
Score = 307 bits (753), Expect = 2e-83
Identities = 141/176 (80%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ D CDIF NL + QRQ+LRKMVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 270 VGFKLLQEDNCDIFQNL-SKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTS 328
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W +M EFFQQGDRERE GM+I
Sbjct: 329 SGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEI 388
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLVHPDAQ+ILDTLE+NRD+Y S I
Sbjct: 389 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI 444
>U18087-1|AAC50458.1| 686|Homo sapiens 3',5'-cyclic AMP
phosphodiesterase HPDE4A6 protein.
Length = 686
Score = 307 bits (753), Expect = 2e-83
Identities = 141/176 (80%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ D CDIF NL + QRQ+LRKMVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 309 VGFKLLQEDNCDIFQNL-SKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTS 367
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W +M EFFQQGDRERE GM+I
Sbjct: 368 SGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEI 427
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLVHPDAQ+ILDTLE+NRD+Y S I
Sbjct: 428 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI 483
>S75213-1|AAB33798.1| 667|Homo sapiens type-IVA cyclic AMP specific
phosphodiesterase protein.
Length = 667
Score = 307 bits (753), Expect = 2e-83
Identities = 141/176 (80%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ D CDIF NL + QRQ+LRKMVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 290 VGFKLLQEDNCDIFQNL-SKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTS 348
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W +M EFFQQGDRERE GM+I
Sbjct: 349 SGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEI 408
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLVHPDAQ+ILDTLE+NRD+Y S I
Sbjct: 409 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI 464
>M37744-1|AAA69697.1| 775|Homo sapiens protein ( Human cyclic AMP
(cAMP)-specific phosphodiesterase mRNA, complete cds. ).
Length = 775
Score = 307 bits (753), Expect = 2e-83
Identities = 141/176 (80%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ D CDIF NL + QRQ+LRKMVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 398 VGFKLLQEDNCDIFQNL-SKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTS 456
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W +M EFFQQGDRERE GM+I
Sbjct: 457 SGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEI 516
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLVHPDAQ+ILDTLE+NRD+Y S I
Sbjct: 517 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI 572
>L20965-1|AAA03588.1| 886|Homo sapiens phosphodiesterase protein.
Length = 886
Score = 307 bits (753), Expect = 2e-83
Identities = 141/176 (80%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ D CDIF NL + QRQ+LRKMVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 509 VGFKLLQEDNCDIFQNL-SKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTS 567
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W +M EFFQQGDRERE GM+I
Sbjct: 568 SGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEI 627
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLVHPDAQ+ILDTLE+NRD+Y S I
Sbjct: 628 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI 683
>BC038234-1|AAH38234.1| 647|Homo sapiens phosphodiesterase 4A,
cAMP-specific (phosphodiesterase E2 dunce homolog,
Drosop protein.
Length = 647
Score = 307 bits (753), Expect = 2e-83
Identities = 141/176 (80%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ D CDIF NL + QRQ+LRKMVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 270 VGFKLLQEDNCDIFQNL-SKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTS 328
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W +M EFFQQGDRERE GM+I
Sbjct: 329 SGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEI 388
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLVHPDAQ+ILDTLE+NRD+Y S I
Sbjct: 389 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI 444
>BC019864-1|AAH19864.1| 647|Homo sapiens phosphodiesterase 4A,
cAMP-specific (phosphodiesterase E2 dunce homolog,
Drosop protein.
Length = 647
Score = 307 bits (753), Expect = 2e-83
Identities = 141/176 (80%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ D CDIF NL + QRQ+LRKMVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 270 VGFKLLQEDNCDIFQNL-SKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTS 328
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W +M EFFQQGDRERE GM+I
Sbjct: 329 SGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEI 388
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLVHPDAQ+ILDTLE+NRD+Y S I
Sbjct: 389 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI 444
>AY618547-1|AAU82096.1| 860|Homo sapiens cyclic AMP phosphodiesterase
PDE4A11 protein.
Length = 860
Score = 307 bits (753), Expect = 2e-83
Identities = 141/176 (80%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ D CDIF NL + QRQ+LRKMVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 483 VGFKLLQEDNCDIFQNL-SKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTS 541
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W +M EFFQQGDRERE GM+I
Sbjct: 542 SGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEI 601
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLVHPDAQ+ILDTLE+NRD+Y S I
Sbjct: 602 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI 657
>AY593872-1|AAT00628.1| 864|Homo sapiens cAMP-specific
phosphodiesterase protein.
Length = 864
Score = 307 bits (753), Expect = 2e-83
Identities = 141/176 (80%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ D CDIF NL + QRQ+LRKMVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 487 VGFKLLQEDNCDIFQNL-SKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTS 545
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W +M EFFQQGDRERE GM+I
Sbjct: 546 SGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEI 605
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLVHPDAQ+ILDTLE+NRD+Y S I
Sbjct: 606 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI 661
>AF073745-1|AAD34217.2| 825|Homo sapiens cyclic AMP-specific
phosphodiesterase HSPDE4A10 protein.
Length = 825
Score = 307 bits (753), Expect = 2e-83
Identities = 141/176 (80%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ D CDIF NL + QRQ+LRKMVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 448 VGFKLLQEDNCDIFQNL-SKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTS 506
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W +M EFFQQGDRERE GM+I
Sbjct: 507 SGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEI 566
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLVHPDAQ+ILDTLE+NRD+Y S I
Sbjct: 567 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI 622
>AF069491-3|AAC35013.1| 647|Homo sapiens cAMP specific
phosphodiesterase 4A variant RD1 protein.
Length = 647
Score = 307 bits (753), Expect = 2e-83
Identities = 141/176 (80%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ D CDIF NL + QRQ+LRKMVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 270 VGFKLLQEDNCDIFQNL-SKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTS 328
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W +M EFFQQGDRERE GM+I
Sbjct: 329 SGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEI 388
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLVHPDAQ+ILDTLE+NRD+Y S I
Sbjct: 389 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI 444
>AF069491-2|AAC35015.1| 860|Homo sapiens putative novel cAMP specific
phosphodiesterase 4A variant protein.
Length = 860
Score = 307 bits (753), Expect = 2e-83
Identities = 141/176 (80%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ D CDIF NL + QRQ+LRKMVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 483 VGFKLLQEDNCDIFQNL-SKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTS 541
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W +M EFFQQGDRERE GM+I
Sbjct: 542 SGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEI 601
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLVHPDAQ+ILDTLE+NRD+Y S I
Sbjct: 602 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI 657
>AF069491-1|AAC35012.1| 886|Homo sapiens cAMP specific
phosphodiesterase 4A variant pde46 protein.
Length = 886
Score = 307 bits (753), Expect = 2e-83
Identities = 141/176 (80%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ D CDIF NL + QRQ+LRKMVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 509 VGFKLLQEDNCDIFQNL-SKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTS 567
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W +M EFFQQGDRERE GM+I
Sbjct: 568 SGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEI 627
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYIVHPLWETWADLVHPDAQ+ILDTLE+NRD+Y S I
Sbjct: 628 SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAI 683
>Z46632-1|CAA86601.1| 712|Homo sapiens 3',5'-cyclic AMP
phosphodiesterase protein.
Length = 712
Score = 302 bits (742), Expect = 4e-82
Identities = 138/176 (78%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL +QR +LR+MVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 464 VGFKLLQAENCDIFQNL-SAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTS 522
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W +M EFFQQGDRERE G+DI
Sbjct: 523 LGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDI 582
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYI HPLWETWADLVHPDAQD+LDTLE+NR++YQS I
Sbjct: 583 SPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKI 638
>U88713-1|AAC51916.1| 700|Homo sapiens phosphodiesterase 4C
protein.
Length = 700
Score = 302 bits (742), Expect = 4e-82
Identities = 138/176 (78%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL +QR +LR+MVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 452 VGFKLLQAENCDIFQNL-SAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTS 510
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W +M EFFQQGDRERE G+DI
Sbjct: 511 LGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDI 570
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYI HPLWETWADLVHPDAQD+LDTLE+NR++YQS I
Sbjct: 571 SPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKI 626
>U88712-1|AAC51915.1| 606|Homo sapiens phosphodiesterase 4C
protein.
Length = 606
Score = 302 bits (742), Expect = 4e-82
Identities = 138/176 (78%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL +QR +LR+MVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 358 VGFKLLQAENCDIFQNL-SAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTS 416
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W +M EFFQQGDRERE G+DI
Sbjct: 417 LGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDI 476
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYI HPLWETWADLVHPDAQD+LDTLE+NR++YQS I
Sbjct: 477 SPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKI 532
>U66349-1|AAB96878.1| 427|Homo sapiens PDE4C-delta109 protein.
Length = 427
Score = 302 bits (742), Expect = 4e-82
Identities = 138/176 (78%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL +QR +LR+MVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 179 VGFKLLQAENCDIFQNL-SAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTS 237
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W +M EFFQQGDRERE G+DI
Sbjct: 238 LGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDI 297
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYI HPLWETWADLVHPDAQD+LDTLE+NR++YQS I
Sbjct: 298 SPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKI 353
>U66348-1|AAB96877.1| 518|Homo sapiens PDE4C-delta54 protein.
Length = 518
Score = 302 bits (742), Expect = 4e-82
Identities = 138/176 (78%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL +QR +LR+MVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 270 VGFKLLQAENCDIFQNL-SAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTS 328
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W +M EFFQQGDRERE G+DI
Sbjct: 329 LGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDI 388
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYI HPLWETWADLVHPDAQD+LDTLE+NR++YQS I
Sbjct: 389 SPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKI 444
>U66347-1|AAB96876.1| 426|Homo sapiens PDE4C-426 protein.
Length = 426
Score = 302 bits (742), Expect = 4e-82
Identities = 138/176 (78%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL +QR +LR+MVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 178 VGFKLLQAENCDIFQNL-SAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTS 236
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W +M EFFQQGDRERE G+DI
Sbjct: 237 LGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDI 296
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYI HPLWETWADLVHPDAQD+LDTLE+NR++YQS I
Sbjct: 297 SPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKI 352
>U66346-1|AAB96875.1| 791|Homo sapiens PDE4C-791 protein.
Length = 791
Score = 302 bits (742), Expect = 4e-82
Identities = 138/176 (78%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL +QR +LR+MVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 543 VGFKLLQAENCDIFQNL-SAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTS 601
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W +M EFFQQGDRERE G+DI
Sbjct: 602 LGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDI 661
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYI HPLWETWADLVHPDAQD+LDTLE+NR++YQS I
Sbjct: 662 SPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKI 717
>L20968-1|AAA03591.1| 251|Homo sapiens phosphodiesterase protein.
Length = 251
Score = 302 bits (742), Expect = 4e-82
Identities = 138/176 (78%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL +QR +LR+MVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 3 VGFKLLQAENCDIFQNL-SAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTS 61
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W +M EFFQQGDRERE G+DI
Sbjct: 62 LGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDI 121
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYI HPLWETWADLVHPDAQD+LDTLE+NR++YQS I
Sbjct: 122 SPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKI 177
>BC109068-1|AAI09069.1| 549|Homo sapiens PDE4C protein protein.
Length = 549
Score = 302 bits (742), Expect = 4e-82
Identities = 138/176 (78%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL +QR +LR+MVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 301 VGFKLLQAENCDIFQNL-SAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTS 359
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W +M EFFQQGDRERE G+DI
Sbjct: 360 LGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDI 419
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYI HPLWETWADLVHPDAQD+LDTLE+NR++YQS I
Sbjct: 420 SPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKI 475
>BC109067-1|AAI09068.1| 481|Homo sapiens PDE4C protein protein.
Length = 481
Score = 302 bits (742), Expect = 4e-82
Identities = 138/176 (78%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL +QR +LR+MVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 233 VGFKLLQAENCDIFQNL-SAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTS 291
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W +M EFFQQGDRERE G+DI
Sbjct: 292 LGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDI 351
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYI HPLWETWADLVHPDAQD+LDTLE+NR++YQS I
Sbjct: 352 SPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKI 407
>AF157816-3|AAD47055.1| 606|Homo sapiens cAMP specific
phosphodiesterase PDE4C2 variant protein.
Length = 606
Score = 302 bits (742), Expect = 4e-82
Identities = 138/176 (78%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL +QR +LR+MVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 358 VGFKLLQAENCDIFQNL-SAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTS 416
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W +M EFFQQGDRERE G+DI
Sbjct: 417 LGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDI 476
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYI HPLWETWADLVHPDAQD+LDTLE+NR++YQS I
Sbjct: 477 SPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKI 532
>AF157816-2|AAD47054.1| 680|Homo sapiens cAMP specific
phosphodiesterase PDE4C3 variant protein.
Length = 680
Score = 302 bits (742), Expect = 4e-82
Identities = 138/176 (78%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL +QR +LR+MVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 432 VGFKLLQAENCDIFQNL-SAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTS 490
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W +M EFFQQGDRERE G+DI
Sbjct: 491 LGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDI 550
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYI HPLWETWADLVHPDAQD+LDTLE+NR++YQS I
Sbjct: 551 SPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKI 606
>AF157816-1|AAD47053.1| 712|Homo sapiens cAMP specific
phosphodiesterase PDE4C1 variant protein.
Length = 712
Score = 302 bits (742), Expect = 4e-82
Identities = 138/176 (78%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL +QR +LR+MVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 464 VGFKLLQAENCDIFQNL-SAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTS 522
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W +M EFFQQGDRERE G+DI
Sbjct: 523 LGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDI 582
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYI HPLWETWADLVHPDAQD+LDTLE+NR++YQS I
Sbjct: 583 SPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKI 638
>AC005759-5|AAC83049.1| 426|Homo sapiens PDE4C-426 protein.
Length = 426
Score = 302 bits (742), Expect = 4e-82
Identities = 138/176 (78%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL +QR +LR+MVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 178 VGFKLLQAENCDIFQNL-SAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTS 236
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W +M EFFQQGDRERE G+DI
Sbjct: 237 LGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDI 296
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYI HPLWETWADLVHPDAQD+LDTLE+NR++YQS I
Sbjct: 297 SPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKI 352
>AC005759-4|AAC83048.1| 427|Homo sapiens PDE4C-delta109 protein.
Length = 427
Score = 302 bits (742), Expect = 4e-82
Identities = 138/176 (78%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL +QR +LR+MVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 179 VGFKLLQAENCDIFQNL-SAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTS 237
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W +M EFFQQGDRERE G+DI
Sbjct: 238 LGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDI 297
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYI HPLWETWADLVHPDAQD+LDTLE+NR++YQS I
Sbjct: 298 SPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKI 353
>AC005759-3|AAC83051.1| 518|Homo sapiens PDE4C-delta54 protein.
Length = 518
Score = 302 bits (742), Expect = 4e-82
Identities = 138/176 (78%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL +QR +LR+MVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 270 VGFKLLQAENCDIFQNL-SAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTS 328
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W +M EFFQQGDRERE G+DI
Sbjct: 329 LGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDI 388
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYI HPLWETWADLVHPDAQD+LDTLE+NR++YQS I
Sbjct: 389 SPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKI 444
>AC005759-2|AAC83047.1| 710|Homo sapiens CN4C_HUMAN protein.
Length = 710
Score = 302 bits (742), Expect = 4e-82
Identities = 138/176 (78%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL +QR +LR+MVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 462 VGFKLLQAENCDIFQNL-SAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTS 520
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W +M EFFQQGDRERE G+DI
Sbjct: 521 LGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDI 580
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYI HPLWETWADLVHPDAQD+LDTLE+NR++YQS I
Sbjct: 581 SPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKI 636
>AC005759-1|AAC83050.1| 782|Homo sapiens PDE4C-791 protein.
Length = 782
Score = 302 bits (742), Expect = 4e-82
Identities = 138/176 (78%), Positives = 157/176 (89%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ + CDIF NL +QR +LR+MVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 534 VGFKLLQAENCDIFQNL-SAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTS 592
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
GVLLLDNY+DRIQVL+NLVHCADLSNPTKPLPLY++W +M EFFQQGDRERE G+DI
Sbjct: 593 LGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDI 652
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
SPMCD+H A++EKSQVGFIDYI HPLWETWADLVHPDAQD+LDTLE+NR++YQS I
Sbjct: 653 SPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKI 708
>U18088-1|AAA98540.1| 323|Homo sapiens 3',5'-cyclic AMP
phosphodiesterase HSPDE4A7A protein.
Length = 323
Score = 226 bits (553), Expect = 3e-59
Identities = 106/136 (77%), Positives = 119/136 (87%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ D CDIF NL + QRQ+LRKMVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 175 VGFKLLQEDNCDIFQNL-SKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTS 233
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W +M EFFQQGDRERE GM+I
Sbjct: 234 SGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEI 293
Query: 377 SPMCDRHNATIEKSQV 424
SPMCD+H A++EKSQV
Sbjct: 294 SPMCDKHTASVEKSQV 309
>AF069491-4|AAC35014.1| 323|Homo sapiens cAMP specific
phosphodiesterase 4A variant 2EL protein.
Length = 323
Score = 226 bits (553), Expect = 3e-59
Identities = 106/136 (77%), Positives = 119/136 (87%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
V FKLLQ D CDIF NL + QRQ+LRKMVIDMVL+TDMSKHM+LLADLKTMVETKKV
Sbjct: 175 VGFKLLQEDNCDIFQNL-SKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTS 233
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W +M EFFQQGDRERE GM+I
Sbjct: 234 SGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEI 293
Query: 377 SPMCDRHNATIEKSQV 424
SPMCD+H A++EKSQV
Sbjct: 294 SPMCDKHTASVEKSQV 309
>AY266362-1|AAP31234.1| 102|Homo sapiens phosphodiesterase isozyme
4 protein.
Length = 102
Score = 190 bits (464), Expect = 2e-48
Identities = 83/102 (81%), Positives = 92/102 (90%)
Frame = +2
Query: 170 MVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGD 349
MVETKKV SGVLLLDNY+DRIQVL N+VHCADLSNPTKPL LY++W +M EFFQQGD
Sbjct: 1 MVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGD 60
Query: 350 REREHGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADL 475
RERE GM+ISPMCD+H A++EKSQVGFIDYIVHPLWETWADL
Sbjct: 61 RERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADL 102
>U86078-1|AAC51872.1| 536|Homo sapiens calmodulin-stimulated
phosphodiesterase PDE1B1 protein.
Length = 536
Score = 125 bits (302), Expect = 9e-29
Identities = 64/161 (39%), Positives = 99/161 (61%)
Frame = +2
Query: 23 FKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSG 202
F+L+Q+D +IF+NL ++E + LR +VI+MVL+TDMS H + +KT ++ +
Sbjct: 301 FRLMQDDEMNIFINLTKDEFVE-LRALVIEMVLATDMSCHFQQVKTMKTALQQLE----- 354
Query: 203 VLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISP 382
D+ + L L+H AD+S+PTK ++ RW LMEEFF+QGD+E E G+ SP
Sbjct: 355 ------RIDKPKALSLLLHAADISHPTKQWLVHSRWTKALMEEFFRQGDKEAELGLPFSP 408
Query: 383 MCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILD 505
+CDR + + +SQ+GFID+IV P + D+ Q + D
Sbjct: 409 LCDRTSTLVAQSQIGFIDFIVEPTFSVLTDVAEKSVQPLAD 449
>U56976-1|AAC50769.1| 536|Homo sapiens calmodulin dependent
phosphodiesterase PDE1B1 protein.
Length = 536
Score = 125 bits (302), Expect = 9e-29
Identities = 64/161 (39%), Positives = 99/161 (61%)
Frame = +2
Query: 23 FKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSG 202
F+L+Q+D +IF+NL ++E + LR +VI+MVL+TDMS H + +KT ++ +
Sbjct: 301 FRLMQDDEMNIFINLTKDEFVE-LRALVIEMVLATDMSCHFQQVKTMKTALQQLE----- 354
Query: 203 VLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISP 382
D+ + L L+H AD+S+PTK ++ RW LMEEFF+QGD+E E G+ SP
Sbjct: 355 ------RIDKPKALSLLLHAADISHPTKQWLVHSRWTKALMEEFFRQGDKEAELGLPFSP 408
Query: 383 MCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILD 505
+CDR + + +SQ+GFID+IV P + D+ Q + D
Sbjct: 409 LCDRTSTLVAQSQIGFIDFIVEPTFSVLTDVAEKSVQPLAD 449
>BX538092-1|CAD98011.1| 399|Homo sapiens hypothetical protein
protein.
Length = 399
Score = 125 bits (302), Expect = 9e-29
Identities = 64/161 (39%), Positives = 99/161 (61%)
Frame = +2
Query: 23 FKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSG 202
F+L+Q+D +IF+NL ++E + LR +VI+MVL+TDMS H + +KT ++ +
Sbjct: 164 FRLMQDDEMNIFINLTKDEFVE-LRALVIEMVLATDMSCHFQQVKTMKTALQQLE----- 217
Query: 203 VLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISP 382
D+ + L L+H AD+S+PTK ++ RW LMEEFF+QGD+E E G+ SP
Sbjct: 218 ------RIDKPKALSLLLHAADISHPTKQWLVHSRWTKALMEEFFRQGDKEAELGLPFSP 271
Query: 383 MCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILD 505
+CDR + + +SQ+GFID+IV P + D+ Q + D
Sbjct: 272 LCDRTSTLVAQSQIGFIDFIVEPTFSVLTDVAEKSVQPLAD 312
>BC032226-1|AAH32226.1| 536|Homo sapiens phosphodiesterase 1B,
calmodulin-dependent protein.
Length = 536
Score = 125 bits (302), Expect = 9e-29
Identities = 64/161 (39%), Positives = 99/161 (61%)
Frame = +2
Query: 23 FKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSG 202
F+L+Q+D +IF+NL ++E + LR +VI+MVL+TDMS H + +KT ++ +
Sbjct: 301 FRLMQDDEMNIFINLTKDEFVE-LRALVIEMVLATDMSCHFQQVKTMKTALQQLE----- 354
Query: 203 VLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISP 382
D+ + L L+H AD+S+PTK ++ RW LMEEFF+QGD+E E G+ SP
Sbjct: 355 ------RIDKPKALSLLLHAADISHPTKQWLVHSRWTKALMEEFFRQGDKEAELGLPFSP 408
Query: 383 MCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILD 505
+CDR + + +SQ+GFID+IV P + D+ Q + D
Sbjct: 409 LCDRTSTLVAQSQIGFIDFIVEPTFSVLTDVAEKSVQPLAD 449
>AJ401609-1|CAC82207.1| 516|Homo sapiens 3'5' cyclic nucleotide
phosphodiesterase 1B2 protein.
Length = 516
Score = 125 bits (302), Expect = 9e-29
Identities = 64/161 (39%), Positives = 99/161 (61%)
Frame = +2
Query: 23 FKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSG 202
F+L+Q+D +IF+NL ++E + LR +VI+MVL+TDMS H + +KT ++ +
Sbjct: 281 FRLMQDDEMNIFINLTKDEFVE-LRALVIEMVLATDMSCHFQQVKTMKTALQQLE----- 334
Query: 203 VLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISP 382
D+ + L L+H AD+S+PTK ++ RW LMEEFF+QGD+E E G+ SP
Sbjct: 335 ------RIDKPKALSLLLHAADISHPTKQWLVHSRWTKALMEEFFRQGDKEAELGLPFSP 388
Query: 383 MCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILD 505
+CDR + + +SQ+GFID+IV P + D+ Q + D
Sbjct: 389 LCDRTSTLVAQSQIGFIDFIVEPTFSVLTDVAEKSVQPLAD 429
>U40370-1|AAC50436.1| 535|Homo sapiens 3',5' cyclic nucleotide
phosphodiesterase protein.
Length = 535
Score = 119 bits (286), Expect = 8e-27
Identities = 59/151 (39%), Positives = 94/151 (62%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A++L+Q + +I +NL +++ R LR +VI+MVLSTDMS H + +++ ++ +
Sbjct: 296 AYRLMQEEEMNILINLSKDDWRD-LRNLVIEMVLSTDMSGHFQQIKNIRNSLQQPE---- 350
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS 379
G+ DR + + ++H AD+S+P K L+ RW LMEEFF QGD+E E G+ S
Sbjct: 351 GI-------DRAKTMSLILHAADISHPAKSWKLHYRWTMALMEEFFLQGDKEAELGLPFS 403
Query: 380 PMCDRHNATIEKSQVGFIDYIVHPLWETWAD 472
P+CDR + + +SQ+GFID+IV P + D
Sbjct: 404 PLCDRKSTMVAQSQIGFIDFIVEPTFSLLTD 434
>BC022480-1|AAH22480.1| 545|Homo sapiens phosphodiesterase 1A,
calmodulin-dependent protein.
Length = 545
Score = 119 bits (286), Expect = 8e-27
Identities = 59/151 (39%), Positives = 94/151 (62%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A++L+Q + +I +NL +++ R LR +VI+MVLSTDMS H + +++ ++ +
Sbjct: 296 AYRLMQEEEMNILINLSKDDWRD-LRNLVIEMVLSTDMSGHFQQIKNIRNSLQQPE---- 350
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS 379
G+ DR + + ++H AD+S+P K L+ RW LMEEFF QGD+E E G+ S
Sbjct: 351 GI-------DRAKTMSLILHAADISHPAKSWKLHYRWTMALMEEFFLQGDKEAELGLPFS 403
Query: 380 PMCDRHNATIEKSQVGFIDYIVHPLWETWAD 472
P+CDR + + +SQ+GFID+IV P + D
Sbjct: 404 PLCDRKSTMVAQSQIGFIDFIVEPTFSLLTD 434
>AL110263-1|CAB53703.1| 519|Homo sapiens hypothetical protein
protein.
Length = 519
Score = 119 bits (286), Expect = 8e-27
Identities = 59/151 (39%), Positives = 94/151 (62%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A++L+Q + +I +NL +++ R LR +VI+MVLSTDMS H + +++ ++ +
Sbjct: 280 AYRLMQEEEMNILINLSKDDWRD-LRNLVIEMVLSTDMSGHFQQIKNIRNSLQQPE---- 334
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS 379
G+ DR + + ++H AD+S+P K L+ RW LMEEFF QGD+E E G+ S
Sbjct: 335 GI-------DRAKTMSLILHAADISHPAKSWKLHYRWTMALMEEFFLQGDKEAELGLPFS 387
Query: 380 PMCDRHNATIEKSQVGFIDYIVHPLWETWAD 472
P+CDR + + +SQ+GFID+IV P + D
Sbjct: 388 PLCDRKSTMVAQSQIGFIDFIVEPTFSLLTD 418
>AJ401610-1|CAC82208.1| 519|Homo sapiens 3'5' cyclic nucleotide
phosphodiesterase 1A5 protein.
Length = 519
Score = 119 bits (286), Expect = 8e-27
Identities = 59/151 (39%), Positives = 94/151 (62%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A++L+Q + +I +NL +++ R LR +VI+MVLSTDMS H + +++ ++ +
Sbjct: 280 AYRLMQEEEMNILINLSKDDWRD-LRNLVIEMVLSTDMSGHFQQIKNIRNSLQQPE---- 334
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS 379
G+ DR + + ++H AD+S+P K L+ RW LMEEFF QGD+E E G+ S
Sbjct: 335 GI-------DRAKTMSLILHAADISHPAKSWKLHYRWTMALMEEFFLQGDKEAELGLPFS 387
Query: 380 PMCDRHNATIEKSQVGFIDYIVHPLWETWAD 472
P+CDR + + +SQ+GFID+IV P + D
Sbjct: 388 PLCDRKSTMVAQSQIGFIDFIVEPTFSLLTD 418
>AB038224-9|BAB20054.1| 518|Homo sapiens calmodulin-dependent
phosphodiesterase protein.
Length = 518
Score = 119 bits (286), Expect = 8e-27
Identities = 59/151 (39%), Positives = 94/151 (62%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A++L+Q + +I +NL +++ R LR +VI+MVLSTDMS H + +++ ++ +
Sbjct: 262 AYRLMQEEEMNILINLSKDDWRD-LRNLVIEMVLSTDMSGHFQQIKNIRNSLQQPE---- 316
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS 379
G+ DR + + ++H AD+S+P K L+ RW LMEEFF QGD+E E G+ S
Sbjct: 317 GI-------DRAKTMSLILHAADISHPAKSWKLHYRWTMALMEEFFLQGDKEAELGLPFS 369
Query: 380 PMCDRHNATIEKSQVGFIDYIVHPLWETWAD 472
P+CDR + + +SQ+GFID+IV P + D
Sbjct: 370 PLCDRKSTMVAQSQIGFIDFIVEPTFSLLTD 400
>AB038224-8|BAB20053.1| 501|Homo sapiens calmodulin-dependent
phosphodiesterase protein.
Length = 501
Score = 119 bits (286), Expect = 8e-27
Identities = 59/151 (39%), Positives = 94/151 (62%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A++L+Q + +I +NL +++ R LR +VI+MVLSTDMS H + +++ ++ +
Sbjct: 262 AYRLMQEEEMNILINLSKDDWRD-LRNLVIEMVLSTDMSGHFQQIKNIRNSLQQPE---- 316
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS 379
G+ DR + + ++H AD+S+P K L+ RW LMEEFF QGD+E E G+ S
Sbjct: 317 GI-------DRAKTMSLILHAADISHPAKSWKLHYRWTMALMEEFFLQGDKEAELGLPFS 369
Query: 380 PMCDRHNATIEKSQVGFIDYIVHPLWETWAD 472
P+CDR + + +SQ+GFID+IV P + D
Sbjct: 370 PLCDRKSTMVAQSQIGFIDFIVEPTFSLLTD 400
>AB038224-7|BAB20057.1| 511|Homo sapiens calmodulin-dependent
phosphodiesterase protein.
Length = 511
Score = 119 bits (286), Expect = 8e-27
Identities = 59/151 (39%), Positives = 94/151 (62%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A++L+Q + +I +NL +++ R LR +VI+MVLSTDMS H + +++ ++ +
Sbjct: 262 AYRLMQEEEMNILINLSKDDWRD-LRNLVIEMVLSTDMSGHFQQIKNIRNSLQQPE---- 316
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS 379
G+ DR + + ++H AD+S+P K L+ RW LMEEFF QGD+E E G+ S
Sbjct: 317 GI-------DRAKTMSLILHAADISHPAKSWKLHYRWTMALMEEFFLQGDKEAELGLPFS 369
Query: 380 PMCDRHNATIEKSQVGFIDYIVHPLWETWAD 472
P+CDR + + +SQ+GFID+IV P + D
Sbjct: 370 PLCDRKSTMVAQSQIGFIDFIVEPTFSLLTD 400
>AB038224-6|BAB20052.1| 552|Homo sapiens calmodulin-dependent
phosphodiesterase protein.
Length = 552
Score = 119 bits (286), Expect = 8e-27
Identities = 59/151 (39%), Positives = 94/151 (62%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A++L+Q + +I +NL +++ R LR +VI+MVLSTDMS H + +++ ++ +
Sbjct: 296 AYRLMQEEEMNILINLSKDDWRD-LRNLVIEMVLSTDMSGHFQQIKNIRNSLQQPE---- 350
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS 379
G+ DR + + ++H AD+S+P K L+ RW LMEEFF QGD+E E G+ S
Sbjct: 351 GI-------DRAKTMSLILHAADISHPAKSWKLHYRWTMALMEEFFLQGDKEAELGLPFS 403
Query: 380 PMCDRHNATIEKSQVGFIDYIVHPLWETWAD 472
P+CDR + + +SQ+GFID+IV P + D
Sbjct: 404 PLCDRKSTMVAQSQIGFIDFIVEPTFSLLTD 434
>AB038224-5|BAB20050.1| 535|Homo sapiens calmodulin-dependent
phosphodiesterase protein.
Length = 535
Score = 119 bits (286), Expect = 8e-27
Identities = 59/151 (39%), Positives = 94/151 (62%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A++L+Q + +I +NL +++ R LR +VI+MVLSTDMS H + +++ ++ +
Sbjct: 296 AYRLMQEEEMNILINLSKDDWRD-LRNLVIEMVLSTDMSGHFQQIKNIRNSLQQPE---- 350
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS 379
G+ DR + + ++H AD+S+P K L+ RW LMEEFF QGD+E E G+ S
Sbjct: 351 GI-------DRAKTMSLILHAADISHPAKSWKLHYRWTMALMEEFFLQGDKEAELGLPFS 403
Query: 380 PMCDRHNATIEKSQVGFIDYIVHPLWETWAD 472
P+CDR + + +SQ+GFID+IV P + D
Sbjct: 404 PLCDRKSTMVAQSQIGFIDFIVEPTFSLLTD 434
>AB038224-4|BAB20056.1| 545|Homo sapiens calmodulin-dependent
phosphodiesterase protein.
Length = 545
Score = 119 bits (286), Expect = 8e-27
Identities = 59/151 (39%), Positives = 94/151 (62%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A++L+Q + +I +NL +++ R LR +VI+MVLSTDMS H + +++ ++ +
Sbjct: 296 AYRLMQEEEMNILINLSKDDWRD-LRNLVIEMVLSTDMSGHFQQIKNIRNSLQQPE---- 350
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS 379
G+ DR + + ++H AD+S+P K L+ RW LMEEFF QGD+E E G+ S
Sbjct: 351 GI-------DRAKTMSLILHAADISHPAKSWKLHYRWTMALMEEFFLQGDKEAELGLPFS 403
Query: 380 PMCDRHNATIEKSQVGFIDYIVHPLWETWAD 472
P+CDR + + +SQ+GFID+IV P + D
Sbjct: 404 PLCDRKSTMVAQSQIGFIDFIVEPTFSLLTD 434
>AB038224-3|BAB20051.1| 536|Homo sapiens calmodulin-dependent
phosphodiesterase protein.
Length = 536
Score = 119 bits (286), Expect = 8e-27
Identities = 59/151 (39%), Positives = 94/151 (62%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A++L+Q + +I +NL +++ R LR +VI+MVLSTDMS H + +++ ++ +
Sbjct: 280 AYRLMQEEEMNILINLSKDDWRD-LRNLVIEMVLSTDMSGHFQQIKNIRNSLQQPE---- 334
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS 379
G+ DR + + ++H AD+S+P K L+ RW LMEEFF QGD+E E G+ S
Sbjct: 335 GI-------DRAKTMSLILHAADISHPAKSWKLHYRWTMALMEEFFLQGDKEAELGLPFS 387
Query: 380 PMCDRHNATIEKSQVGFIDYIVHPLWETWAD 472
P+CDR + + +SQ+GFID+IV P + D
Sbjct: 388 PLCDRKSTMVAQSQIGFIDFIVEPTFSLLTD 418
>AB038224-2|BAB20049.1| 519|Homo sapiens calmodulin-dependent
phosphodiesterase protein.
Length = 519
Score = 119 bits (286), Expect = 8e-27
Identities = 59/151 (39%), Positives = 94/151 (62%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A++L+Q + +I +NL +++ R LR +VI+MVLSTDMS H + +++ ++ +
Sbjct: 280 AYRLMQEEEMNILINLSKDDWRD-LRNLVIEMVLSTDMSGHFQQIKNIRNSLQQPE---- 334
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS 379
G+ DR + + ++H AD+S+P K L+ RW LMEEFF QGD+E E G+ S
Sbjct: 335 GI-------DRAKTMSLILHAADISHPAKSWKLHYRWTMALMEEFFLQGDKEAELGLPFS 387
Query: 380 PMCDRHNATIEKSQVGFIDYIVHPLWETWAD 472
P+CDR + + +SQ+GFID+IV P + D
Sbjct: 388 PLCDRKSTMVAQSQIGFIDFIVEPTFSLLTD 418
>AB038224-1|BAB20055.1| 529|Homo sapiens calmodulin-dependent
phosphodiesterase protein.
Length = 529
Score = 119 bits (286), Expect = 8e-27
Identities = 59/151 (39%), Positives = 94/151 (62%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A++L+Q + +I +NL +++ R LR +VI+MVLSTDMS H + +++ ++ +
Sbjct: 280 AYRLMQEEEMNILINLSKDDWRD-LRNLVIEMVLSTDMSGHFQQIKNIRNSLQQPE---- 334
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS 379
G+ DR + + ++H AD+S+P K L+ RW LMEEFF QGD+E E G+ S
Sbjct: 335 GI-------DRAKTMSLILHAADISHPAKSWKLHYRWTMALMEEFFLQGDKEAELGLPFS 387
Query: 380 PMCDRHNATIEKSQVGFIDYIVHPLWETWAD 472
P+CDR + + +SQ+GFID+IV P + D
Sbjct: 388 PLCDRKSTMVAQSQIGFIDFIVEPTFSLLTD 418
>U40372-1|AAA96961.1| 564|Homo sapiens PDE1C3 protein.
Length = 564
Score = 116 bits (280), Expect = 4e-26
Identities = 60/163 (36%), Positives = 98/163 (60%), Gaps = 1/163 (0%)
Frame = +2
Query: 20 AFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
A++LLQ+D +I +NL +++ R+ R +VI+MV++TDMS H + +KT ++ +
Sbjct: 160 AYRLLQDDEEMNILINLSKDDWRE-FRTLVIEMVMATDMSCHFQQIKAMKTALQQPEAI- 217
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
++ + L ++H AD+S+P K L+ RW L+EEFF+QGDRE E G+
Sbjct: 218 ----------EKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPF 267
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILD 505
SP+CDR + + +SQVGFID+IV P + D+ ++D
Sbjct: 268 SPLCDRKSTMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLID 310
>U40371-1|AAC50437.1| 634|Homo sapiens 3',5' cyclic nucleotide
phosphodiesterase protein.
Length = 634
Score = 116 bits (280), Expect = 4e-26
Identities = 60/163 (36%), Positives = 98/163 (60%), Gaps = 1/163 (0%)
Frame = +2
Query: 20 AFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
A++LLQ+D +I +NL +++ R+ R +VI+MV++TDMS H + +KT ++ +
Sbjct: 305 AYRLLQDDEEMNILINLSKDDWRE-FRTLVIEMVMATDMSCHFQQIKAMKTALQQPEAI- 362
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
++ + L ++H AD+S+P K L+ RW L+EEFF+QGDRE E G+
Sbjct: 363 ----------EKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPF 412
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILD 505
SP+CDR + + +SQVGFID+IV P + D+ ++D
Sbjct: 413 SPLCDRKSTMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLID 455
>BC022525-1|AAH22525.1| 634|Homo sapiens PDE1C protein protein.
Length = 634
Score = 116 bits (280), Expect = 4e-26
Identities = 60/163 (36%), Positives = 98/163 (60%), Gaps = 1/163 (0%)
Frame = +2
Query: 20 AFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
A++LLQ+D +I +NL +++ R+ R +VI+MV++TDMS H + +KT ++ +
Sbjct: 305 AYRLLQDDEEMNILINLSKDDWRE-FRTLVIEMVMATDMSCHFQQIKAMKTALQQPEAI- 362
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
++ + L ++H AD+S+P K L+ RW L+EEFF+QGDRE E G+
Sbjct: 363 ----------EKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPF 412
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILD 505
SP+CDR + + +SQVGFID+IV P + D+ ++D
Sbjct: 413 SPLCDRKSTMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLID 455
>BC022479-1|AAH22479.1| 634|Homo sapiens PDE1C protein protein.
Length = 634
Score = 116 bits (280), Expect = 4e-26
Identities = 60/163 (36%), Positives = 98/163 (60%), Gaps = 1/163 (0%)
Frame = +2
Query: 20 AFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
A++LLQ+D +I +NL +++ R+ R +VI+MV++TDMS H + +KT ++ +
Sbjct: 305 AYRLLQDDEEMNILINLSKDDWRE-FRTLVIEMVMATDMSCHFQQIKAMKTALQQPEAI- 362
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
++ + L ++H AD+S+P K L+ RW L+EEFF+QGDRE E G+
Sbjct: 363 ----------EKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPF 412
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILD 505
SP+CDR + + +SQVGFID+IV P + D+ ++D
Sbjct: 413 SPLCDRKSTMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLID 455
>AK091734-1|BAC03734.1| 769|Homo sapiens (EC 3.1.4.17). protein.
Length = 769
Score = 116 bits (280), Expect = 4e-26
Identities = 60/163 (36%), Positives = 98/163 (60%), Gaps = 1/163 (0%)
Frame = +2
Query: 20 AFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
A++LLQ+D +I +NL +++ R+ R +VI+MV++TDMS H + +KT ++ +
Sbjct: 365 AYRLLQDDEEMNILINLSKDDWRE-FRTLVIEMVMATDMSCHFQQIKAMKTALQQPEAI- 422
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
++ + L ++H AD+S+P K L+ RW L+EEFF+QGDRE E G+
Sbjct: 423 ----------EKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPF 472
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILD 505
SP+CDR + + +SQVGFID+IV P + D+ ++D
Sbjct: 473 SPLCDRKSTMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLID 515
>AC006377-1|AAS07516.1| 591|Homo sapiens unknown protein.
Length = 591
Score = 116 bits (280), Expect = 4e-26
Identities = 60/163 (36%), Positives = 98/163 (60%), Gaps = 1/163 (0%)
Frame = +2
Query: 20 AFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
A++LLQ+D +I +NL +++ R+ R +VI+MV++TDMS H + +KT ++ +
Sbjct: 262 AYRLLQDDEEMNILINLSKDDWRE-FRTLVIEMVMATDMSCHFQQIKAMKTALQQPEAI- 319
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
++ + L ++H AD+S+P K L+ RW L+EEFF+QGDRE E G+
Sbjct: 320 ----------EKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPF 369
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILD 505
SP+CDR + + +SQVGFID+IV P + D+ ++D
Sbjct: 370 SPLCDRKSTMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLID 412
>BC075822-1|AAH75822.1| 829|Homo sapiens phosphodiesterase 8A
protein.
Length = 829
Score = 108 bits (260), Expect = 1e-23
Identities = 65/188 (34%), Positives = 102/188 (54%), Gaps = 13/188 (6%)
Frame = +2
Query: 17 VAFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSL-----------LAD 160
+AF+L D C+IF N+ + R TLR+ +IDMVL+T+M+KH LA
Sbjct: 632 LAFQLTTGDDKCNIFKNMERNDYR-TLRQGIIDMVLATEMTKHFEHVNKFVNSINKPLAT 690
Query: 161 LKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQ 340
L+ ET K +L +R + L+ CAD+SNP +PL W A + EE+F
Sbjct: 691 LEENGETDKNQEVINTMLRTPENRTLIKRMLIKCADVSNPCRPLQYCIEWAARISEEYFS 750
Query: 341 QGDREREHGMD-ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEE 517
Q D E++ G+ + P+ DR+ +I KSQ+ FIDY + +++ W V D D++ L+
Sbjct: 751 QTDEEKQQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFV--DLPDLMQHLDN 808
Query: 518 NRDYYQSM 541
N Y++ +
Sbjct: 809 NFKYWKGL 816
>BC060762-1|AAH60762.1| 829|Homo sapiens phosphodiesterase 8A
protein.
Length = 829
Score = 108 bits (260), Expect = 1e-23
Identities = 65/188 (34%), Positives = 102/188 (54%), Gaps = 13/188 (6%)
Frame = +2
Query: 17 VAFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSL-----------LAD 160
+AF+L D C+IF N+ + R TLR+ +IDMVL+T+M+KH LA
Sbjct: 632 LAFQLTTGDDKCNIFKNMERNDYR-TLRQGIIDMVLATEMTKHFEHVNKFVNSINKPLAT 690
Query: 161 LKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQ 340
L+ ET K +L +R + L+ CAD+SNP +PL W A + EE+F
Sbjct: 691 LEENGETDKNQEVINTMLRTPENRTLIKRMLIKCADVSNPCRPLQYCIEWAARISEEYFS 750
Query: 341 QGDREREHGMD-ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEE 517
Q D E++ G+ + P+ DR+ +I KSQ+ FIDY + +++ W V D D++ L+
Sbjct: 751 QTDEEKQQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFV--DLPDLMQHLDN 808
Query: 518 NRDYYQSM 541
N Y++ +
Sbjct: 809 NFKYWKGL 816
>BC048317-1|AAH48317.1| 305|Homo sapiens PDE8A protein protein.
Length = 305
Score = 108 bits (260), Expect = 1e-23
Identities = 65/188 (34%), Positives = 102/188 (54%), Gaps = 13/188 (6%)
Frame = +2
Query: 17 VAFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSL-----------LAD 160
+AF+L D C+IF N+ + R TLR+ +IDMVL+T+M+KH LA
Sbjct: 108 LAFQLTTGDDKCNIFKNMERNDYR-TLRQGIIDMVLATEMTKHFEHVNKFVNSINKPLAT 166
Query: 161 LKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQ 340
L+ ET K +L +R + L+ CAD+SNP +PL W A + EE+F
Sbjct: 167 LEENGETDKNQEVINTMLRTPENRTLIKRMLIKCADVSNPCRPLQYCIEWAARISEEYFS 226
Query: 341 QGDREREHGMD-ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEE 517
Q D E++ G+ + P+ DR+ +I KSQ+ FIDY + +++ W V D D++ L+
Sbjct: 227 QTDEEKQQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFV--DLPDLMQHLDN 284
Query: 518 NRDYYQSM 541
N Y++ +
Sbjct: 285 NFKYWKGL 292
>AF388187-1|AAL18614.1| 582|Homo sapiens cAMP phosphodiesterase
PDE8A5 protein.
Length = 582
Score = 108 bits (260), Expect = 1e-23
Identities = 65/188 (34%), Positives = 102/188 (54%), Gaps = 13/188 (6%)
Frame = +2
Query: 17 VAFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSL-----------LAD 160
+AF+L D C+IF N+ + R TLR+ +IDMVL+T+M+KH LA
Sbjct: 385 LAFQLTTGDDKCNIFKNMERNDYR-TLRQGIIDMVLATEMTKHFEHVNKFVNSINKPLAT 443
Query: 161 LKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQ 340
L+ ET K +L +R + L+ CAD+SNP +PL W A + EE+F
Sbjct: 444 LEENGETDKNQEVINTMLRTPENRTLIKRMLIKCADVSNPCRPLQYCIEWAARISEEYFS 503
Query: 341 QGDREREHGMD-ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEE 517
Q D E++ G+ + P+ DR+ +I KSQ+ FIDY + +++ W V D D++ L+
Sbjct: 504 QTDEEKQQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFV--DLPDLMQHLDN 561
Query: 518 NRDYYQSM 541
N Y++ +
Sbjct: 562 NFKYWKGL 569
>AF388186-1|AAL18613.1| 582|Homo sapiens cAMP phosphodiesterase
PDE8A4 protein.
Length = 582
Score = 108 bits (260), Expect = 1e-23
Identities = 65/188 (34%), Positives = 102/188 (54%), Gaps = 13/188 (6%)
Frame = +2
Query: 17 VAFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSL-----------LAD 160
+AF+L D C+IF N+ + R TLR+ +IDMVL+T+M+KH LA
Sbjct: 385 LAFQLTTGDDKCNIFKNMERNDYR-TLRQGIIDMVLATEMTKHFEHVNKFVNSINKPLAT 443
Query: 161 LKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQ 340
L+ ET K +L +R + L+ CAD+SNP +PL W A + EE+F
Sbjct: 444 LEENGETDKNQEVINTMLRTPENRTLIKRMLIKCADVSNPCRPLQYCIEWAARISEEYFS 503
Query: 341 QGDREREHGMD-ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEE 517
Q D E++ G+ + P+ DR+ +I KSQ+ FIDY + +++ W V D D++ L+
Sbjct: 504 QTDEEKQQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFV--DLPDLMQHLDN 561
Query: 518 NRDYYQSM 541
N Y++ +
Sbjct: 562 NFKYWKGL 569
>AF388185-1|AAL18612.1| 449|Homo sapiens cAMP phosphodiesterase
PDE8A3 protein.
Length = 449
Score = 108 bits (260), Expect = 1e-23
Identities = 65/188 (34%), Positives = 102/188 (54%), Gaps = 13/188 (6%)
Frame = +2
Query: 17 VAFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSL-----------LAD 160
+AF+L D C+IF N+ + R TLR+ +IDMVL+T+M+KH LA
Sbjct: 252 LAFQLTTGDDKCNIFKNMERNDYR-TLRQGIIDMVLATEMTKHFEHVNKFVNSINKPLAT 310
Query: 161 LKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQ 340
L+ ET K +L +R + L+ CAD+SNP +PL W A + EE+F
Sbjct: 311 LEENGETDKNQEVINTMLRTPENRTLIKRMLIKCADVSNPCRPLQYCIEWAARISEEYFS 370
Query: 341 QGDREREHGMD-ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEE 517
Q D E++ G+ + P+ DR+ +I KSQ+ FIDY + +++ W V D D++ L+
Sbjct: 371 QTDEEKQQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFV--DLPDLMQHLDN 428
Query: 518 NRDYYQSM 541
N Y++ +
Sbjct: 429 NFKYWKGL 436
>AF388184-1|AAL18611.1| 783|Homo sapiens cAMP phosphodiesterase
PDE8A2 protein.
Length = 783
Score = 108 bits (260), Expect = 1e-23
Identities = 65/188 (34%), Positives = 102/188 (54%), Gaps = 13/188 (6%)
Frame = +2
Query: 17 VAFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSL-----------LAD 160
+AF+L D C+IF N+ + R TLR+ +IDMVL+T+M+KH LA
Sbjct: 586 LAFQLTTGDDKCNIFKNMERNDYR-TLRQGIIDMVLATEMTKHFEHVNKFVNSINKPLAT 644
Query: 161 LKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQ 340
L+ ET K +L +R + L+ CAD+SNP +PL W A + EE+F
Sbjct: 645 LEENGETDKNQEVINTMLRTPENRTLIKRMLIKCADVSNPCRPLQYCIEWAARISEEYFS 704
Query: 341 QGDREREHGMD-ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEE 517
Q D E++ G+ + P+ DR+ +I KSQ+ FIDY + +++ W V D D++ L+
Sbjct: 705 QTDEEKQQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFV--DLPDLMQHLDN 762
Query: 518 NRDYYQSM 541
N Y++ +
Sbjct: 763 NFKYWKGL 770
>AF388183-1|AAL18610.1| 829|Homo sapiens cAMP phosphodiesterase
PDE8A1 protein.
Length = 829
Score = 108 bits (260), Expect = 1e-23
Identities = 65/188 (34%), Positives = 102/188 (54%), Gaps = 13/188 (6%)
Frame = +2
Query: 17 VAFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSL-----------LAD 160
+AF+L D C+IF N+ + R TLR+ +IDMVL+T+M+KH LA
Sbjct: 632 LAFQLTTGDDKCNIFKNMERNDYR-TLRQGIIDMVLATEMTKHFEHVNKFVNSINKPLAT 690
Query: 161 LKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQ 340
L+ ET K +L +R + L+ CAD+SNP +PL W A + EE+F
Sbjct: 691 LEENGETDKNQEVINTMLRTPENRTLIKRMLIKCADVSNPCRPLQYCIEWAARISEEYFS 750
Query: 341 QGDREREHGMD-ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEE 517
Q D E++ G+ + P+ DR+ +I KSQ+ FIDY + +++ W V D D++ L+
Sbjct: 751 QTDEEKQQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFV--DLPDLMQHLDN 808
Query: 518 NRDYYQSM 541
N Y++ +
Sbjct: 809 NFKYWKGL 816
>AF332653-1|AAK57641.1| 829|Homo sapiens cAMP-specific cyclic
nucleotide phosphodiesterase PDE8A1 protein.
Length = 829
Score = 108 bits (260), Expect = 1e-23
Identities = 65/188 (34%), Positives = 102/188 (54%), Gaps = 13/188 (6%)
Frame = +2
Query: 17 VAFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSL-----------LAD 160
+AF+L D C+IF N+ + R TLR+ +IDMVL+T+M+KH LA
Sbjct: 632 LAFQLTTGDDKCNIFKNMERNDYR-TLRQGIIDMVLATEMTKHFEHVNKFVNSINKPLAT 690
Query: 161 LKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQ 340
L+ ET K +L +R + L+ CAD+SNP +PL W A + EE+F
Sbjct: 691 LEENGETDKNQEVINTMLRTPENRTLIKRMLIKCADVSNPCRPLQYCIEWAARISEEYFS 750
Query: 341 QGDREREHGMD-ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEE 517
Q D E++ G+ + P+ DR+ +I KSQ+ FIDY + +++ W V D D++ L+
Sbjct: 751 QTDEEKQQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFV--DLPDLMQHLDN 808
Query: 518 NRDYYQSM 541
N Y++ +
Sbjct: 809 NFKYWKGL 816
>AF056490-1|AAC39763.1| 713|Homo sapiens cAMP-specific
phosphodiesterase 8A protein.
Length = 713
Score = 108 bits (260), Expect = 1e-23
Identities = 65/188 (34%), Positives = 102/188 (54%), Gaps = 13/188 (6%)
Frame = +2
Query: 17 VAFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSL-----------LAD 160
+AF+L D C+IF N+ + R TLR+ +IDMVL+T+M+KH LA
Sbjct: 516 LAFQLTTGDDKCNIFKNMERNDYR-TLRQGIIDMVLATEMTKHFEHVNKFVNSINKPLAT 574
Query: 161 LKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQ 340
L+ ET K +L +R + L+ CAD+SNP +PL W A + EE+F
Sbjct: 575 LEENGETDKNQEVINTMLRTPENRTLIKRMLIKCADVSNPCRPLQYCIEWAARISEEYFS 634
Query: 341 QGDREREHGMD-ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEE 517
Q D E++ G+ + P+ DR+ +I KSQ+ FIDY + +++ W V D D++ L+
Sbjct: 635 QTDEEKQQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFV--DLPDLMQHLDN 692
Query: 518 NRDYYQSM 541
N Y++ +
Sbjct: 693 NFKYWKGL 700
>BT007016-1|AAP35662.1| 533|Homo sapiens phosphodiesterase 9A
protein.
Length = 533
Score = 105 bits (253), Expect = 8e-23
Identities = 54/175 (30%), Positives = 101/175 (57%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAF++L C+IF N+ + +Q +R+ +I ++L+TDM++H ++ K +E +
Sbjct: 328 VAFQILAEPECNIFSNIPPDGFKQ-IRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 386
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ L ++++ L+ C D+SN +P+ + + WV L+EE+F Q DRE+ G+ +
Sbjct: 387 EEHMTL------LKMI--LIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPV 438
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+P DR T +Q+GFI +++ P++ET L + +L L E+RD Y+ +
Sbjct: 439 APFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 493
>BC009047-1|AAH09047.1| 533|Homo sapiens phosphodiesterase 9A
protein.
Length = 533
Score = 105 bits (253), Expect = 8e-23
Identities = 54/175 (30%), Positives = 101/175 (57%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAF++L C+IF N+ + +Q +R+ +I ++L+TDM++H ++ K +E +
Sbjct: 328 VAFQILAEPECNIFSNIPPDGFKQ-IRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 386
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ L ++++ L+ C D+SN +P+ + + WV L+EE+F Q DRE+ G+ +
Sbjct: 387 EEHMTL------LKMI--LIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPV 438
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+P DR T +Q+GFI +++ P++ET L + +L L E+RD Y+ +
Sbjct: 439 APFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 493
>AY701187-1|AAV84271.1| 485|Homo sapiens phosphodiesterase PDE9A21
protein.
Length = 485
Score = 105 bits (253), Expect = 8e-23
Identities = 54/175 (30%), Positives = 101/175 (57%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAF++L C+IF N+ + +Q +R+ +I ++L+TDM++H ++ K +E +
Sbjct: 280 VAFQILAEPECNIFSNIPPDGFKQ-IRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 338
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ L ++++ L+ C D+SN +P+ + + WV L+EE+F Q DRE+ G+ +
Sbjct: 339 EEHMTL------LKMI--LIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPV 390
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+P DR T +Q+GFI +++ P++ET L + +L L E+RD Y+ +
Sbjct: 391 APFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 445
>AY242121-1|AAO88210.1| 492|Homo sapiens type 9 cGMP-specific
phosphodiesterase isoform 5 protein.
Length = 492
Score = 105 bits (253), Expect = 8e-23
Identities = 54/175 (30%), Positives = 101/175 (57%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAF++L C+IF N+ + +Q +R+ +I ++L+TDM++H ++ K +E +
Sbjct: 287 VAFQILAEPECNIFSNIPPDGFKQ-IRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 345
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ L ++++ L+ C D+SN +P+ + + WV L+EE+F Q DRE+ G+ +
Sbjct: 346 EEHMTL------LKMI--LIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPV 397
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+P DR T +Q+GFI +++ P++ET L + +L L E+RD Y+ +
Sbjct: 398 APFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 452
>AY196314-1|AAO34700.1| 386|Homo sapiens phosphodiesterase PDE9A20
protein.
Length = 386
Score = 105 bits (253), Expect = 8e-23
Identities = 54/175 (30%), Positives = 101/175 (57%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAF++L C+IF N+ + +Q +R+ +I ++L+TDM++H ++ K +E +
Sbjct: 181 VAFQILAEPECNIFSNIPPDGFKQ-IRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 239
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ L ++++ L+ C D+SN +P+ + + WV L+EE+F Q DRE+ G+ +
Sbjct: 240 EEHMTL------LKMI--LIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPV 291
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+P DR T +Q+GFI +++ P++ET L + +L L E+RD Y+ +
Sbjct: 292 APFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 346
>AY196313-1|AAO34699.1| 386|Homo sapiens phosphodiesterase PDE9A19
protein.
Length = 386
Score = 105 bits (253), Expect = 8e-23
Identities = 54/175 (30%), Positives = 101/175 (57%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAF++L C+IF N+ + +Q +R+ +I ++L+TDM++H ++ K +E +
Sbjct: 181 VAFQILAEPECNIFSNIPPDGFKQ-IRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 239
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ L ++++ L+ C D+SN +P+ + + WV L+EE+F Q DRE+ G+ +
Sbjct: 240 EEHMTL------LKMI--LIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPV 291
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+P DR T +Q+GFI +++ P++ET L + +L L E+RD Y+ +
Sbjct: 292 APFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 346
>AY196312-1|AAO34698.1| 567|Homo sapiens phosphodiesterase PDE9A18
protein.
Length = 567
Score = 105 bits (253), Expect = 8e-23
Identities = 54/175 (30%), Positives = 101/175 (57%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAF++L C+IF N+ + +Q +R+ +I ++L+TDM++H ++ K +E +
Sbjct: 362 VAFQILAEPECNIFSNIPPDGFKQ-IRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 420
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ L ++++ L+ C D+SN +P+ + + WV L+EE+F Q DRE+ G+ +
Sbjct: 421 EEHMTL------LKMI--LIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPV 472
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+P DR T +Q+GFI +++ P++ET L + +L L E+RD Y+ +
Sbjct: 473 APFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 527
>AY196311-1|AAO34697.1| 552|Homo sapiens phosphodiesterase PDE9A17
protein.
Length = 552
Score = 105 bits (253), Expect = 8e-23
Identities = 54/175 (30%), Positives = 101/175 (57%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAF++L C+IF N+ + +Q +R+ +I ++L+TDM++H ++ K +E +
Sbjct: 347 VAFQILAEPECNIFSNIPPDGFKQ-IRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 405
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ L ++++ L+ C D+SN +P+ + + WV L+EE+F Q DRE+ G+ +
Sbjct: 406 EEHMTL------LKMI--LIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPV 457
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+P DR T +Q+GFI +++ P++ET L + +L L E+RD Y+ +
Sbjct: 458 APFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 512
>AY196310-1|AAO34696.1| 526|Homo sapiens phosphodiesterase PDE9A16
protein.
Length = 526
Score = 105 bits (253), Expect = 8e-23
Identities = 54/175 (30%), Positives = 101/175 (57%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAF++L C+IF N+ + +Q +R+ +I ++L+TDM++H ++ K +E +
Sbjct: 321 VAFQILAEPECNIFSNIPPDGFKQ-IRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 379
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ L ++++ L+ C D+SN +P+ + + WV L+EE+F Q DRE+ G+ +
Sbjct: 380 EEHMTL------LKMI--LIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPV 431
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+P DR T +Q+GFI +++ P++ET L + +L L E+RD Y+ +
Sbjct: 432 APFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 486
>AY196309-1|AAO34695.1| 376|Homo sapiens phosphodiesterase PDE9A15
protein.
Length = 376
Score = 105 bits (253), Expect = 8e-23
Identities = 54/175 (30%), Positives = 101/175 (57%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAF++L C+IF N+ + +Q +R+ +I ++L+TDM++H ++ K +E +
Sbjct: 171 VAFQILAEPECNIFSNIPPDGFKQ-IRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 229
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ L ++++ L+ C D+SN +P+ + + WV L+EE+F Q DRE+ G+ +
Sbjct: 230 EEHMTL------LKMI--LIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPV 281
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+P DR T +Q+GFI +++ P++ET L + +L L E+RD Y+ +
Sbjct: 282 APFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 336
>AY196308-1|AAO34694.1| 386|Homo sapiens phosphodiesterase PDE9A14
protein.
Length = 386
Score = 105 bits (253), Expect = 8e-23
Identities = 54/175 (30%), Positives = 101/175 (57%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAF++L C+IF N+ + +Q +R+ +I ++L+TDM++H ++ K +E +
Sbjct: 181 VAFQILAEPECNIFSNIPPDGFKQ-IRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 239
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ L ++++ L+ C D+SN +P+ + + WV L+EE+F Q DRE+ G+ +
Sbjct: 240 EEHMTL------LKMI--LIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPV 291
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+P DR T +Q+GFI +++ P++ET L + +L L E+RD Y+ +
Sbjct: 292 APFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 346
>AY196307-1|AAO34693.1| 491|Homo sapiens phosphodiesterase PDE9A13
protein.
Length = 491
Score = 105 bits (253), Expect = 8e-23
Identities = 54/175 (30%), Positives = 101/175 (57%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAF++L C+IF N+ + +Q +R+ +I ++L+TDM++H ++ K +E +
Sbjct: 286 VAFQILAEPECNIFSNIPPDGFKQ-IRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 344
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ L ++++ L+ C D+SN +P+ + + WV L+EE+F Q DRE+ G+ +
Sbjct: 345 EEHMTL------LKMI--LIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPV 396
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+P DR T +Q+GFI +++ P++ET L + +L L E+RD Y+ +
Sbjct: 397 APFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 451
>AY196306-1|AAO34692.1| 459|Homo sapiens phosphodiesterase PDE9A12
protein.
Length = 459
Score = 105 bits (253), Expect = 8e-23
Identities = 54/175 (30%), Positives = 101/175 (57%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAF++L C+IF N+ + +Q +R+ +I ++L+TDM++H ++ K +E +
Sbjct: 254 VAFQILAEPECNIFSNIPPDGFKQ-IRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 312
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ L ++++ L+ C D+SN +P+ + + WV L+EE+F Q DRE+ G+ +
Sbjct: 313 EEHMTL------LKMI--LIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPV 364
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+P DR T +Q+GFI +++ P++ET L + +L L E+RD Y+ +
Sbjct: 365 APFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 419
>AY196305-1|AAO34691.1| 376|Homo sapiens phosphodiesterase PDE9A11
protein.
Length = 376
Score = 105 bits (253), Expect = 8e-23
Identities = 54/175 (30%), Positives = 101/175 (57%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAF++L C+IF N+ + +Q +R+ +I ++L+TDM++H ++ K +E +
Sbjct: 171 VAFQILAEPECNIFSNIPPDGFKQ-IRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 229
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ L ++++ L+ C D+SN +P+ + + WV L+EE+F Q DRE+ G+ +
Sbjct: 230 EEHMTL------LKMI--LIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPV 281
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+P DR T +Q+GFI +++ P++ET L + +L L E+RD Y+ +
Sbjct: 282 APFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 336
>AY196304-1|AAO34690.1| 433|Homo sapiens phosphodiesterase PDE9A10
protein.
Length = 433
Score = 105 bits (253), Expect = 8e-23
Identities = 54/175 (30%), Positives = 101/175 (57%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAF++L C+IF N+ + +Q +R+ +I ++L+TDM++H ++ K +E +
Sbjct: 228 VAFQILAEPECNIFSNIPPDGFKQ-IRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 286
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ L ++++ L+ C D+SN +P+ + + WV L+EE+F Q DRE+ G+ +
Sbjct: 287 EEHMTL------LKMI--LIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPV 338
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+P DR T +Q+GFI +++ P++ET L + +L L E+RD Y+ +
Sbjct: 339 APFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 393
>AY196303-1|AAO34689.1| 507|Homo sapiens phosphodiesterase PDE9A9
protein.
Length = 507
Score = 105 bits (253), Expect = 8e-23
Identities = 54/175 (30%), Positives = 101/175 (57%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAF++L C+IF N+ + +Q +R+ +I ++L+TDM++H ++ K +E +
Sbjct: 302 VAFQILAEPECNIFSNIPPDGFKQ-IRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 360
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ L ++++ L+ C D+SN +P+ + + WV L+EE+F Q DRE+ G+ +
Sbjct: 361 EEHMTL------LKMI--LIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPV 412
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+P DR T +Q+GFI +++ P++ET L + +L L E+RD Y+ +
Sbjct: 413 APFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 467
>AY196302-1|AAO34688.1| 386|Homo sapiens phosphodiesterase PDE9A8
protein.
Length = 386
Score = 105 bits (253), Expect = 8e-23
Identities = 54/175 (30%), Positives = 101/175 (57%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAF++L C+IF N+ + +Q +R+ +I ++L+TDM++H ++ K +E +
Sbjct: 181 VAFQILAEPECNIFSNIPPDGFKQ-IRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 239
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ L ++++ L+ C D+SN +P+ + + WV L+EE+F Q DRE+ G+ +
Sbjct: 240 EEHMTL------LKMI--LIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPV 291
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+P DR T +Q+GFI +++ P++ET L + +L L E+RD Y+ +
Sbjct: 292 APFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 346
>AY196301-1|AAO34687.1| 386|Homo sapiens phosphodiesterase PDE9A7
protein.
Length = 386
Score = 105 bits (253), Expect = 8e-23
Identities = 54/175 (30%), Positives = 101/175 (57%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAF++L C+IF N+ + +Q +R+ +I ++L+TDM++H ++ K +E +
Sbjct: 181 VAFQILAEPECNIFSNIPPDGFKQ-IRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 239
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ L ++++ L+ C D+SN +P+ + + WV L+EE+F Q DRE+ G+ +
Sbjct: 240 EEHMTL------LKMI--LIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPV 291
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+P DR T +Q+GFI +++ P++ET L + +L L E+RD Y+ +
Sbjct: 292 APFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 346
>AY196300-1|AAO34686.1| 492|Homo sapiens phosphodiesterase PDE9A6
protein.
Length = 492
Score = 105 bits (253), Expect = 8e-23
Identities = 54/175 (30%), Positives = 101/175 (57%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAF++L C+IF N+ + +Q +R+ +I ++L+TDM++H ++ K +E +
Sbjct: 287 VAFQILAEPECNIFSNIPPDGFKQ-IRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 345
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ L ++++ L+ C D+SN +P+ + + WV L+EE+F Q DRE+ G+ +
Sbjct: 346 EEHMTL------LKMI--LIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPV 397
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+P DR T +Q+GFI +++ P++ET L + +L L E+RD Y+ +
Sbjct: 398 APFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 452
>AY196299-1|AAO34685.1| 540|Homo sapiens phosphodiesterase PDE9A5
protein.
Length = 540
Score = 105 bits (253), Expect = 8e-23
Identities = 54/175 (30%), Positives = 101/175 (57%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAF++L C+IF N+ + +Q +R+ +I ++L+TDM++H ++ K +E +
Sbjct: 335 VAFQILAEPECNIFSNIPPDGFKQ-IRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 393
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ L ++++ L+ C D+SN +P+ + + WV L+EE+F Q DRE+ G+ +
Sbjct: 394 EEHMTL------LKMI--LIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPV 445
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+P DR T +Q+GFI +++ P++ET L + +L L E+RD Y+ +
Sbjct: 446 APFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 500
>AP001747-1|BAA95552.1| 593|Homo sapiens CGMP-specific 3',5'-cyclic
phosphodiesterase type 9, EC 3.1.4.17. protein.
Length = 593
Score = 105 bits (253), Expect = 8e-23
Identities = 54/175 (30%), Positives = 101/175 (57%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAF++L C+IF N+ + +Q +R+ +I ++L+TDM++H ++ K +E +
Sbjct: 388 VAFQILAEPECNIFSNIPPDGFKQ-IRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 446
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ L ++++ L+ C D+SN +P+ + + WV L+EE+F Q DRE+ G+ +
Sbjct: 447 EEHMTL------LKMI--LIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPV 498
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+P DR T +Q+GFI +++ P++ET L + +L L E+RD Y+ +
Sbjct: 499 APFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 553
>AF067226-1|AAC26726.1| 465|Homo sapiens cGMP phosphodiesterase A4
protein.
Length = 465
Score = 105 bits (253), Expect = 8e-23
Identities = 54/175 (30%), Positives = 101/175 (57%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAF++L C+IF N+ + +Q +R+ +I ++L+TDM++H ++ K +E +
Sbjct: 260 VAFQILAEPECNIFSNIPPDGFKQ-IRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 318
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ L ++++ L+ C D+SN +P+ + + WV L+EE+F Q DRE+ G+ +
Sbjct: 319 EEHMTL------LKMI--LIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPV 370
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+P DR T +Q+GFI +++ P++ET L + +L L E+RD Y+ +
Sbjct: 371 APFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 425
>AF067225-1|AAC26725.1| 466|Homo sapiens cGMP phosphodiesterase A3
protein.
Length = 466
Score = 105 bits (253), Expect = 8e-23
Identities = 54/175 (30%), Positives = 101/175 (57%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAF++L C+IF N+ + +Q +R+ +I ++L+TDM++H ++ K +E +
Sbjct: 261 VAFQILAEPECNIFSNIPPDGFKQ-IRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 319
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ L ++++ L+ C D+SN +P+ + + WV L+EE+F Q DRE+ G+ +
Sbjct: 320 EEHMTL------LKMI--LIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPV 371
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+P DR T +Q+GFI +++ P++ET L + +L L E+RD Y+ +
Sbjct: 372 APFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 426
>AF067224-1|AAC26724.1| 533|Homo sapiens cGMP phosphodiesterase A2
protein.
Length = 533
Score = 105 bits (253), Expect = 8e-23
Identities = 54/175 (30%), Positives = 101/175 (57%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAF++L C+IF N+ + +Q +R+ +I ++L+TDM++H ++ K +E +
Sbjct: 328 VAFQILAEPECNIFSNIPPDGFKQ-IRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 386
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ L ++++ L+ C D+SN +P+ + + WV L+EE+F Q DRE+ G+ +
Sbjct: 387 EEHMTL------LKMI--LIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPV 438
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+P DR T +Q+GFI +++ P++ET L + +L L E+RD Y+ +
Sbjct: 439 APFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 493
>AF067223-1|AAC26723.1| 593|Homo sapiens cGMP phosphodiesterase A1
protein.
Length = 593
Score = 105 bits (253), Expect = 8e-23
Identities = 54/175 (30%), Positives = 101/175 (57%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAF++L C+IF N+ + +Q +R+ +I ++L+TDM++H ++ K +E +
Sbjct: 388 VAFQILAEPECNIFSNIPPDGFKQ-IRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 446
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ L ++++ L+ C D+SN +P+ + + WV L+EE+F Q DRE+ G+ +
Sbjct: 447 EEHMTL------LKMI--LIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPV 498
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+P DR T +Q+GFI +++ P++ET L + +L L E+RD Y+ +
Sbjct: 499 APFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 553
>AF048837-1|AAC39778.1| 593|Homo sapiens cGMP-specific
phosphodiesterase protein.
Length = 593
Score = 105 bits (253), Expect = 8e-23
Identities = 54/175 (30%), Positives = 101/175 (57%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAF++L C+IF N+ + +Q +R+ +I ++L+TDM++H ++ K +E +
Sbjct: 388 VAFQILAEPECNIFSNIPPDGFKQ-IRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 446
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ L ++++ L+ C D+SN +P+ + + WV L+EE+F Q DRE+ G+ +
Sbjct: 447 EEHMTL------LKMI--LIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPV 498
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+P DR T +Q+GFI +++ P++ET L + +L L E+RD Y+ +
Sbjct: 499 APFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 553
>AB017602-1|BAA88847.1| 593|Homo sapiens cGMP phosphodiesterase
protein.
Length = 593
Score = 105 bits (253), Expect = 8e-23
Identities = 54/175 (30%), Positives = 101/175 (57%)
Frame = +2
Query: 17 VAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAG 196
VAF++L C+IF N+ + +Q +R+ +I ++L+TDM++H ++ K +E +
Sbjct: 388 VAFQILAEPECNIFSNIPPDGFKQ-IRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 446
Query: 197 SGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDI 376
+ L ++++ L+ C D+SN +P+ + + WV L+EE+F Q DRE+ G+ +
Sbjct: 447 EEHMTL------LKMI--LIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPV 498
Query: 377 SPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+P DR T +Q+GFI +++ P++ET L + +L L E+RD Y+ +
Sbjct: 499 APFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 553
>BC035144-1|AAH35144.1| 385|Homo sapiens PDE8B protein protein.
Length = 385
Score = 101 bits (241), Expect = 2e-21
Identities = 60/189 (31%), Positives = 102/189 (53%), Gaps = 12/189 (6%)
Frame = +2
Query: 11 TRVAFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVE--- 178
T +AF+L D C+IF N+ R TLR+ +IDMVL+T+M+KH + +
Sbjct: 189 TALAFQLTVKDTKCNIFKNIDRNHYR-TLRQAIIDMVLATEMTKHFEHVNKFVNSINKPM 247
Query: 179 TKKVAGS-------GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFF 337
++ GS G L+N +I + ++ CAD++NP +PL L W + EE+F
Sbjct: 248 AAEIEGSDCECNPAGKNFLEN---QILIKRMMIKCADVANPCRPLDLCIEWAGRISEEYF 304
Query: 338 QQGDREREHGMD-ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE 514
Q D E+ G+ + P+ DR+ +I KSQ+ FIDY + +++ W H A ++ L
Sbjct: 305 AQTDEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFAHLPA--LMQHLA 362
Query: 515 ENRDYYQSM 541
+N +++++
Sbjct: 363 DNYKHWKTL 371
>BC047627-1|AAH47627.1| 241|Homo sapiens PDE8B protein protein.
Length = 241
Score = 100 bits (240), Expect = 3e-21
Identities = 58/186 (31%), Positives = 101/186 (54%), Gaps = 9/186 (4%)
Frame = +2
Query: 11 TRVAFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVE--- 178
T +AF+L D C+IF N+ R TLR+ +IDMVL+T+M+KH + +
Sbjct: 45 TALAFQLTVKDTKCNIFKNIDRNHYR-TLRQAIIDMVLATEMTKHFEHVNKFVNSINKPM 103
Query: 179 TKKVAGSGVLLLD---NYTD-RIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQG 346
++ GS N+ + +I + ++ CAD++NP +PL L W + EE+F Q
Sbjct: 104 AAEIEGSDCECNPAGKNFPENQILIKRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQT 163
Query: 347 DREREHGMD-ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENR 523
D E+ G+ + P+ DR+ +I KSQ+ FIDY + +++ W H A ++ L +N
Sbjct: 164 DEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFAHLPA--LMQHLADNY 221
Query: 524 DYYQSM 541
+++++
Sbjct: 222 KHWKTL 227
>AY423729-1|AAS00492.1| 350|Homo sapiens proliferation-inducing
gene 22 protein protein.
Length = 350
Score = 100 bits (240), Expect = 3e-21
Identities = 58/186 (31%), Positives = 101/186 (54%), Gaps = 9/186 (4%)
Frame = +2
Query: 11 TRVAFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVE--- 178
T +AF+L D C+IF N+ R TLR+ +IDMVL+T+M+KH + +
Sbjct: 154 TALAFQLTVKDTKCNIFKNIDRNHYR-TLRQAIIDMVLATEMTKHFEHVNKFVNSINKPM 212
Query: 179 TKKVAGSGVLLLD---NYTD-RIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQG 346
++ GS N+ + +I + ++ CAD++NP +PL L W + EE+F Q
Sbjct: 213 AAEIEGSDCECNPAGKNFPENQILIKRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQT 272
Query: 347 DREREHGMD-ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENR 523
D E+ G+ + P+ DR+ +I KSQ+ FIDY + +++ W H A ++ L +N
Sbjct: 273 DEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFAHLPA--LMQHLADNY 330
Query: 524 DYYQSM 541
+++++
Sbjct: 331 KHWKTL 336
>AY129950-3|AAN71727.1| 788|Homo sapiens cAMP-specific
phosphodiesterase 8B3 protein.
Length = 788
Score = 100 bits (240), Expect = 3e-21
Identities = 58/186 (31%), Positives = 101/186 (54%), Gaps = 9/186 (4%)
Frame = +2
Query: 11 TRVAFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVE--- 178
T +AF+L D C+IF N+ R TLR+ +IDMVL+T+M+KH + +
Sbjct: 592 TALAFQLTVKDTKCNIFKNIDRNHYR-TLRQAIIDMVLATEMTKHFEHVNKFVNSINKPM 650
Query: 179 TKKVAGSGVLLLD---NYTD-RIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQG 346
++ GS N+ + +I + ++ CAD++NP +PL L W + EE+F Q
Sbjct: 651 AAEIEGSDCECNPAGKNFPENQILIKRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQT 710
Query: 347 DREREHGMD-ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENR 523
D E+ G+ + P+ DR+ +I KSQ+ FIDY + +++ W H A ++ L +N
Sbjct: 711 DEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFAHLPA--LMQHLADNY 768
Query: 524 DYYQSM 541
+++++
Sbjct: 769 KHWKTL 774
>AY129950-2|AAN71726.1| 838|Homo sapiens cAMP-specific
phosphodiesterase 8B2 protein.
Length = 838
Score = 100 bits (240), Expect = 3e-21
Identities = 58/186 (31%), Positives = 101/186 (54%), Gaps = 9/186 (4%)
Frame = +2
Query: 11 TRVAFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVE--- 178
T +AF+L D C+IF N+ R TLR+ +IDMVL+T+M+KH + +
Sbjct: 642 TALAFQLTVKDTKCNIFKNIDRNHYR-TLRQAIIDMVLATEMTKHFEHVNKFVNSINKPM 700
Query: 179 TKKVAGSGVLLLD---NYTD-RIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQG 346
++ GS N+ + +I + ++ CAD++NP +PL L W + EE+F Q
Sbjct: 701 AAEIEGSDCECNPAGKNFPENQILIKRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQT 760
Query: 347 DREREHGMD-ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENR 523
D E+ G+ + P+ DR+ +I KSQ+ FIDY + +++ W H A ++ L +N
Sbjct: 761 DEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFAHLPA--LMQHLADNY 818
Query: 524 DYYQSM 541
+++++
Sbjct: 819 KHWKTL 824
>AY129950-1|AAN71725.1| 885|Homo sapiens cAMP-specific
phosphodiesterase 8B1 protein.
Length = 885
Score = 100 bits (240), Expect = 3e-21
Identities = 58/186 (31%), Positives = 101/186 (54%), Gaps = 9/186 (4%)
Frame = +2
Query: 11 TRVAFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVE--- 178
T +AF+L D C+IF N+ R TLR+ +IDMVL+T+M+KH + +
Sbjct: 689 TALAFQLTVKDTKCNIFKNIDRNHYR-TLRQAIIDMVLATEMTKHFEHVNKFVNSINKPM 747
Query: 179 TKKVAGSGVLLLD---NYTD-RIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQG 346
++ GS N+ + +I + ++ CAD++NP +PL L W + EE+F Q
Sbjct: 748 AAEIEGSDCECNPAGKNFPENQILIKRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQT 807
Query: 347 DREREHGMD-ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENR 523
D E+ G+ + P+ DR+ +I KSQ+ FIDY + +++ W H A ++ L +N
Sbjct: 808 DEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFAHLPA--LMQHLADNY 865
Query: 524 DYYQSM 541
+++++
Sbjct: 866 KHWKTL 871
>AY129949-1|AAN71724.1| 788|Homo sapiens cAMP-specific
phosphodiesterase 8B3 protein.
Length = 788
Score = 100 bits (240), Expect = 3e-21
Identities = 58/186 (31%), Positives = 101/186 (54%), Gaps = 9/186 (4%)
Frame = +2
Query: 11 TRVAFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVE--- 178
T +AF+L D C+IF N+ R TLR+ +IDMVL+T+M+KH + +
Sbjct: 592 TALAFQLTVKDTKCNIFKNIDRNHYR-TLRQAIIDMVLATEMTKHFEHVNKFVNSINKPM 650
Query: 179 TKKVAGSGVLLLD---NYTD-RIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQG 346
++ GS N+ + +I + ++ CAD++NP +PL L W + EE+F Q
Sbjct: 651 AAEIEGSDCECNPAGKNFPENQILIKRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQT 710
Query: 347 DREREHGMD-ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENR 523
D E+ G+ + P+ DR+ +I KSQ+ FIDY + +++ W H A ++ L +N
Sbjct: 711 DEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFAHLPA--LMQHLADNY 768
Query: 524 DYYQSM 541
+++++
Sbjct: 769 KHWKTL 774
>AY129948-1|AAN71723.1| 838|Homo sapiens cAMP-specific
phosphodiesterase 8B2 protein.
Length = 838
Score = 100 bits (240), Expect = 3e-21
Identities = 58/186 (31%), Positives = 101/186 (54%), Gaps = 9/186 (4%)
Frame = +2
Query: 11 TRVAFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVE--- 178
T +AF+L D C+IF N+ R TLR+ +IDMVL+T+M+KH + +
Sbjct: 642 TALAFQLTVKDTKCNIFKNIDRNHYR-TLRQAIIDMVLATEMTKHFEHVNKFVNSINKPM 700
Query: 179 TKKVAGSGVLLLD---NYTD-RIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQG 346
++ GS N+ + +I + ++ CAD++NP +PL L W + EE+F Q
Sbjct: 701 AAEIEGSDCECNPAGKNFPENQILIKRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQT 760
Query: 347 DREREHGMD-ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENR 523
D E+ G+ + P+ DR+ +I KSQ+ FIDY + +++ W H A ++ L +N
Sbjct: 761 DEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFAHLPA--LMQHLADNY 818
Query: 524 DYYQSM 541
+++++
Sbjct: 819 KHWKTL 824
>AL831924-1|CAD38584.1| 843|Homo sapiens hypothetical protein
protein.
Length = 843
Score = 100 bits (240), Expect = 3e-21
Identities = 58/186 (31%), Positives = 101/186 (54%), Gaps = 9/186 (4%)
Frame = +2
Query: 11 TRVAFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVE--- 178
T +AF+L D C+IF N+ R TLR+ +IDMVL+T+M+KH + +
Sbjct: 647 TALAFQLTVKDTKCNIFKNIDRNHYR-TLRQAIIDMVLATEMTKHFEHVNKFVNSINKPM 705
Query: 179 TKKVAGSGVLLLD---NYTD-RIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQG 346
++ GS N+ + +I + ++ CAD++NP +PL L W + EE+F Q
Sbjct: 706 AAEIEGSDCECNPAGKNFPENQILIKRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQT 765
Query: 347 DREREHGMD-ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENR 523
D E+ G+ + P+ DR+ +I KSQ+ FIDY + +++ W H A ++ L +N
Sbjct: 766 DEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFAHLPA--LMQHLADNY 823
Query: 524 DYYQSM 541
+++++
Sbjct: 824 KHWKTL 829
>AF079529-1|AAC69564.2| 885|Homo sapiens cAMP-specific
phosphodiesterase 8B1 protein.
Length = 885
Score = 100 bits (240), Expect = 3e-21
Identities = 58/186 (31%), Positives = 101/186 (54%), Gaps = 9/186 (4%)
Frame = +2
Query: 11 TRVAFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVE--- 178
T +AF+L D C+IF N+ R TLR+ +IDMVL+T+M+KH + +
Sbjct: 689 TALAFQLTVKDTKCNIFKNIDRNHYR-TLRQAIIDMVLATEMTKHFEHVNKFVNSINKPM 747
Query: 179 TKKVAGSGVLLLD---NYTD-RIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQG 346
++ GS N+ + +I + ++ CAD++NP +PL L W + EE+F Q
Sbjct: 748 AAEIEGSDCECNPAGKNFPENQILIKRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQT 807
Query: 347 DREREHGMD-ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENR 523
D E+ G+ + P+ DR+ +I KSQ+ FIDY + +++ W H A ++ L +N
Sbjct: 808 DEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFAHLPA--LMQHLADNY 865
Query: 524 DYYQSM 541
+++++
Sbjct: 866 KHWKTL 871
>AB085827-1|BAC53765.1| 865|Homo sapiens phosphodiesterase 8B4
protein.
Length = 865
Score = 100 bits (240), Expect = 3e-21
Identities = 58/186 (31%), Positives = 101/186 (54%), Gaps = 9/186 (4%)
Frame = +2
Query: 11 TRVAFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVE--- 178
T +AF+L D C+IF N+ R TLR+ +IDMVL+T+M+KH + +
Sbjct: 669 TALAFQLTVKDTKCNIFKNIDRNHYR-TLRQAIIDMVLATEMTKHFEHVNKFVNSINKPM 727
Query: 179 TKKVAGSGVLLLD---NYTD-RIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQG 346
++ GS N+ + +I + ++ CAD++NP +PL L W + EE+F Q
Sbjct: 728 AAEIEGSDCECNPAGKNFPENQILIKRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQT 787
Query: 347 DREREHGMD-ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENR 523
D E+ G+ + P+ DR+ +I KSQ+ FIDY + +++ W H A ++ L +N
Sbjct: 788 DEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFAHLPA--LMQHLADNY 845
Query: 524 DYYQSM 541
+++++
Sbjct: 846 KHWKTL 851
>AB085826-1|BAC53764.1| 830|Homo sapiens phosphodiesterase 8B3
protein.
Length = 830
Score = 100 bits (240), Expect = 3e-21
Identities = 58/186 (31%), Positives = 101/186 (54%), Gaps = 9/186 (4%)
Frame = +2
Query: 11 TRVAFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVE--- 178
T +AF+L D C+IF N+ R TLR+ +IDMVL+T+M+KH + +
Sbjct: 634 TALAFQLTVKDTKCNIFKNIDRNHYR-TLRQAIIDMVLATEMTKHFEHVNKFVNSINKPM 692
Query: 179 TKKVAGSGVLLLD---NYTD-RIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQG 346
++ GS N+ + +I + ++ CAD++NP +PL L W + EE+F Q
Sbjct: 693 AAEIEGSDCECNPAGKNFPENQILIKRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQT 752
Query: 347 DREREHGMD-ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENR 523
D E+ G+ + P+ DR+ +I KSQ+ FIDY + +++ W H A ++ L +N
Sbjct: 753 DEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFAHLPA--LMQHLADNY 810
Query: 524 DYYQSM 541
+++++
Sbjct: 811 KHWKTL 816
>AB085825-1|BAC53763.1| 788|Homo sapiens phosphodiestearse 8B2
protein.
Length = 788
Score = 100 bits (240), Expect = 3e-21
Identities = 58/186 (31%), Positives = 101/186 (54%), Gaps = 9/186 (4%)
Frame = +2
Query: 11 TRVAFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVE--- 178
T +AF+L D C+IF N+ R TLR+ +IDMVL+T+M+KH + +
Sbjct: 592 TALAFQLTVKDTKCNIFKNIDRNHYR-TLRQAIIDMVLATEMTKHFEHVNKFVNSINKPM 650
Query: 179 TKKVAGSGVLLLD---NYTD-RIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQG 346
++ GS N+ + +I + ++ CAD++NP +PL L W + EE+F Q
Sbjct: 651 AAEIEGSDCECNPAGKNFPENQILIKRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQT 710
Query: 347 DREREHGMD-ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENR 523
D E+ G+ + P+ DR+ +I KSQ+ FIDY + +++ W H A ++ L +N
Sbjct: 711 DEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFAHLPA--LMQHLADNY 768
Query: 524 DYYQSM 541
+++++
Sbjct: 769 KHWKTL 774
>AB085824-1|BAC53762.1| 885|Homo sapiens phosphodiesterase 8B1
protein.
Length = 885
Score = 100 bits (240), Expect = 3e-21
Identities = 58/186 (31%), Positives = 101/186 (54%), Gaps = 9/186 (4%)
Frame = +2
Query: 11 TRVAFKLLQNDG-CDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVE--- 178
T +AF+L D C+IF N+ R TLR+ +IDMVL+T+M+KH + +
Sbjct: 689 TALAFQLTVKDTKCNIFKNIDRNHYR-TLRQAIIDMVLATEMTKHFEHVNKFVNSINKPM 747
Query: 179 TKKVAGSGVLLLD---NYTD-RIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQG 346
++ GS N+ + +I + ++ CAD++NP +PL L W + EE+F Q
Sbjct: 748 AAEIEGSDCECNPAGKNFPENQILIKRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQT 807
Query: 347 DREREHGMD-ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENR 523
D E+ G+ + P+ DR+ +I KSQ+ FIDY + +++ W H A ++ L +N
Sbjct: 808 DEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFAHLPA--LMQHLADNY 865
Query: 524 DYYQSM 541
+++++
Sbjct: 866 KHWKTL 871
>AL109778-1|CAB52432.1| 178|Homo sapiens PDE8A; phosphodiesterase
8A protein.
Length = 178
Score = 97.5 bits (232), Expect = 3e-20
Identities = 56/164 (34%), Positives = 89/164 (54%), Gaps = 12/164 (7%)
Frame = +2
Query: 86 QTLRKMVIDMVLSTDMSKHMSL-----------LADLKTMVETKKVAGSGVLLLDNYTDR 232
+TLR+ +IDMVL+T+M+KH LA L+ ET K +L +R
Sbjct: 4 RTLRQGIIDMVLATEMTKHFEHVNKFVNSINKPLATLEENGETDKNQEVINTMLRTPENR 63
Query: 233 IQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMD-ISPMCDRHNATI 409
+ L+ CAD+SNP +PL W A + EE+F Q D E++ G+ + P+ DR+ +I
Sbjct: 64 TLIKRMLIKCADVSNPCRPLQYCIEWAARISEEYFSQTDEEKQQGLPVVMPVFDRNTCSI 123
Query: 410 EKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
KSQ+ FIDY + +++ W V D D++ L+ N Y++ +
Sbjct: 124 PKSQISFIDYFITDMFDAWDAFV--DLPDLMQHLDNNFKYWKGL 165
>U67932-1|AAB65772.1| 456|Homo sapiens cAMP phosphodiesterase PDE7
protein.
Length = 456
Score = 96.7 bits (230), Expect = 5e-20
Identities = 53/152 (34%), Positives = 87/152 (57%)
Frame = +2
Query: 14 RVAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVA 193
R A LL+ G +F +L E RQ + + ++L+TD+S+ L+ ++ ++
Sbjct: 261 RSAVGLLRESG--LFSHL-PLESRQQMETQIGALILATDISRQNEYLSLFRSHLDR---- 313
Query: 194 GSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMD 373
G L L++ R VL+ + CAD+ NP + L K+W + EEFF QGD E+++ +
Sbjct: 314 --GDLCLEDTRHRHLVLQMALKCADICNPCRTWELSKQWSEKVTEEFFHQGDIEKKYHLG 371
Query: 374 ISPMCDRHNATIEKSQVGFIDYIVHPLWETWA 469
+SP+CDRH +I Q+GF+ Y+V PL+ WA
Sbjct: 372 VSPLCDRHTESIANIQIGFMTYLVEPLFTEWA 403
>L12052-1|AAA35644.2| 482|Homo sapiens cAMP phosphodiesterase PDE7
protein.
Length = 482
Score = 96.7 bits (230), Expect = 5e-20
Identities = 53/152 (34%), Positives = 87/152 (57%)
Frame = +2
Query: 14 RVAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVA 193
R A LL+ G +F +L E RQ + + ++L+TD+S+ L+ ++ ++
Sbjct: 287 RSAVGLLRESG--LFSHL-PLESRQQMETQIGALILATDISRQNEYLSLFRSHLDR---- 339
Query: 194 GSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMD 373
G L L++ R VL+ + CAD+ NP + L K+W + EEFF QGD E+++ +
Sbjct: 340 --GDLCLEDTRHRHLVLQMALKCADICNPCRTWELSKQWSEKVTEEFFHQGDIEKKYHLG 397
Query: 374 ISPMCDRHNATIEKSQVGFIDYIVHPLWETWA 469
+SP+CDRH +I Q+GF+ Y+V PL+ WA
Sbjct: 398 VSPLCDRHTESIANIQIGFMTYLVEPLFTEWA 429
>BC126360-1|AAI26361.1| 456|Homo sapiens phosphodiesterase 7A
protein.
Length = 456
Score = 96.7 bits (230), Expect = 5e-20
Identities = 53/152 (34%), Positives = 87/152 (57%)
Frame = +2
Query: 14 RVAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVA 193
R A LL+ G +F +L E RQ + + ++L+TD+S+ L+ ++ ++
Sbjct: 261 RSAVGLLRESG--LFSHL-PLESRQQMETQIGALILATDISRQNEYLSLFRSHLDR---- 313
Query: 194 GSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMD 373
G L L++ R VL+ + CAD+ NP + L K+W + EEFF QGD E+++ +
Sbjct: 314 --GDLCLEDTRHRHLVLQMALKCADICNPCRTWELSKQWSEKVTEEFFHQGDIEKKYHLG 371
Query: 374 ISPMCDRHNATIEKSQVGFIDYIVHPLWETWA 469
+SP+CDRH +I Q+GF+ Y+V PL+ WA
Sbjct: 372 VSPLCDRHTESIANIQIGFMTYLVEPLFTEWA 403
>EF108327-1|ABL14249.1| 502|Homo sapiens phosphodiesterase PDE7B2
protein.
Length = 502
Score = 90.6 bits (215), Expect = 3e-18
Identities = 46/159 (28%), Positives = 90/159 (56%), Gaps = 2/159 (1%)
Frame = +2
Query: 74 EEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENL 253
+E Q + + + ++L+TD+++ L LK + K L L++ DR +L+
Sbjct: 317 KEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKD------LRLEDAQDRHFMLQIA 370
Query: 254 VHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATIEKSQVGFI 433
+ CAD+ NP + + K+W + EEF++QG+ E++ ++ISP+C++ +I Q+GF+
Sbjct: 371 LKCADICNPCRIWEMSKQWSERVCEEFYRQGELEQKFELEISPLCNQQKDSIPSIQIGFM 430
Query: 434 DYIVHPLWETWADLVHPD--AQDILDTLEENRDYYQSMI 544
YIV PL+ WA ++++L L N+ ++S++
Sbjct: 431 SYIVEPLFREWAHFTGNSTLSENMLGHLAHNKAQWKSLL 469
>BC075083-1|AAH75083.1| 450|Homo sapiens phosphodiesterase 7B
protein.
Length = 450
Score = 90.6 bits (215), Expect = 3e-18
Identities = 46/159 (28%), Positives = 90/159 (56%), Gaps = 2/159 (1%)
Frame = +2
Query: 74 EEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENL 253
+E Q + + + ++L+TD+++ L LK + K L L++ DR +L+
Sbjct: 265 KEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKD------LRLEDAQDRHFMLQIA 318
Query: 254 VHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATIEKSQVGFI 433
+ CAD+ NP + + K+W + EEF++QG+ E++ ++ISP+C++ +I Q+GF+
Sbjct: 319 LKCADICNPCRIWEMSKQWSERVCEEFYRQGELEQKFELEISPLCNQQKDSIPSIQIGFM 378
Query: 434 DYIVHPLWETWADLVHPD--AQDILDTLEENRDYYQSMI 544
YIV PL+ WA ++++L L N+ ++S++
Sbjct: 379 SYIVEPLFREWAHFTGNSTLSENMLGHLAHNKAQWKSLL 417
>BC075082-1|AAH75082.1| 450|Homo sapiens phosphodiesterase 7B
protein.
Length = 450
Score = 90.6 bits (215), Expect = 3e-18
Identities = 46/159 (28%), Positives = 90/159 (56%), Gaps = 2/159 (1%)
Frame = +2
Query: 74 EEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENL 253
+E Q + + + ++L+TD+++ L LK + K L L++ DR +L+
Sbjct: 265 KEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKD------LRLEDAQDRHFMLQIA 318
Query: 254 VHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATIEKSQVGFI 433
+ CAD+ NP + + K+W + EEF++QG+ E++ ++ISP+C++ +I Q+GF+
Sbjct: 319 LKCADICNPCRIWEMSKQWSERVCEEFYRQGELEQKFELEISPLCNQQKDSIPSIQIGFM 378
Query: 434 DYIVHPLWETWADLVHPD--AQDILDTLEENRDYYQSMI 544
YIV PL+ WA ++++L L N+ ++S++
Sbjct: 379 SYIVEPLFREWAHFTGNSTLSENMLGHLAHNKAQWKSLL 417
>AL360178-1|CAH73075.1| 450|Homo sapiens phosphodiesterase 7B
protein.
Length = 450
Score = 90.6 bits (215), Expect = 3e-18
Identities = 46/159 (28%), Positives = 90/159 (56%), Gaps = 2/159 (1%)
Frame = +2
Query: 74 EEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENL 253
+E Q + + + ++L+TD+++ L LK + K L L++ DR +L+
Sbjct: 265 KEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKD------LRLEDAQDRHFMLQIA 318
Query: 254 VHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATIEKSQVGFI 433
+ CAD+ NP + + K+W + EEF++QG+ E++ ++ISP+C++ +I Q+GF+
Sbjct: 319 LKCADICNPCRIWEMSKQWSERVCEEFYRQGELEQKFELEISPLCNQQKDSIPSIQIGFM 378
Query: 434 DYIVHPLWETWADLVHPD--AQDILDTLEENRDYYQSMI 544
YIV PL+ WA ++++L L N+ ++S++
Sbjct: 379 SYIVEPLFREWAHFTGNSTLSENMLGHLAHNKAQWKSLL 417
>AL138828-4|CAI95287.1| 450|Homo sapiens phosphodiesterase 7B
protein.
Length = 450
Score = 90.6 bits (215), Expect = 3e-18
Identities = 46/159 (28%), Positives = 90/159 (56%), Gaps = 2/159 (1%)
Frame = +2
Query: 74 EEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENL 253
+E Q + + + ++L+TD+++ L LK + K L L++ DR +L+
Sbjct: 265 KEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKD------LRLEDAQDRHFMLQIA 318
Query: 254 VHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATIEKSQVGFI 433
+ CAD+ NP + + K+W + EEF++QG+ E++ ++ISP+C++ +I Q+GF+
Sbjct: 319 LKCADICNPCRIWEMSKQWSERVCEEFYRQGELEQKFELEISPLCNQQKDSIPSIQIGFM 378
Query: 434 DYIVHPLWETWADLVHPD--AQDILDTLEENRDYYQSMI 544
YIV PL+ WA ++++L L N+ ++S++
Sbjct: 379 SYIVEPLFREWAHFTGNSTLSENMLGHLAHNKAQWKSLL 417
>AL133319-1|CAH73332.1| 450|Homo sapiens phosphodiesterase 7B
protein.
Length = 450
Score = 90.6 bits (215), Expect = 3e-18
Identities = 46/159 (28%), Positives = 90/159 (56%), Gaps = 2/159 (1%)
Frame = +2
Query: 74 EEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENL 253
+E Q + + + ++L+TD+++ L LK + K L L++ DR +L+
Sbjct: 265 KEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKD------LRLEDAQDRHFMLQIA 318
Query: 254 VHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATIEKSQVGFI 433
+ CAD+ NP + + K+W + EEF++QG+ E++ ++ISP+C++ +I Q+GF+
Sbjct: 319 LKCADICNPCRIWEMSKQWSERVCEEFYRQGELEQKFELEISPLCNQQKDSIPSIQIGFM 378
Query: 434 DYIVHPLWETWADLVHPD--AQDILDTLEENRDYYQSMI 544
YIV PL+ WA ++++L L N+ ++S++
Sbjct: 379 SYIVEPLFREWAHFTGNSTLSENMLGHLAHNKAQWKSLL 417
>AJ251860-1|CAB92441.1| 450|Homo sapiens phosphodiesterase 7B
protein.
Length = 450
Score = 90.6 bits (215), Expect = 3e-18
Identities = 46/159 (28%), Positives = 90/159 (56%), Gaps = 2/159 (1%)
Frame = +2
Query: 74 EEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENL 253
+E Q + + + ++L+TD+++ L LK + K L L++ DR +L+
Sbjct: 265 KEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKD------LRLEDAQDRHFMLQIA 318
Query: 254 VHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATIEKSQVGFI 433
+ CAD+ NP + + K+W + EEF++QG+ E++ ++ISP+C++ +I Q+GF+
Sbjct: 319 LKCADICNPCRIWEMSKQWSERVCEEFYRQGELEQKFELEISPLCNQQKDSIPSIQIGFM 378
Query: 434 DYIVHPLWETWADLVHPD--AQDILDTLEENRDYYQSMI 544
YIV PL+ WA ++++L L N+ ++S++
Sbjct: 379 SYIVEPLFREWAHFTGNSTLSENMLGHLAHNKAQWKSLL 417
>AB209990-1|BAE06072.1| 586|Homo sapiens PDE7B variant protein
protein.
Length = 586
Score = 90.6 bits (215), Expect = 3e-18
Identities = 46/159 (28%), Positives = 90/159 (56%), Gaps = 2/159 (1%)
Frame = +2
Query: 74 EEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENL 253
+E Q + + + ++L+TD+++ L LK + K L L++ DR +L+
Sbjct: 401 KEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKD------LRLEDAQDRHFMLQIA 454
Query: 254 VHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATIEKSQVGFI 433
+ CAD+ NP + + K+W + EEF++QG+ E++ ++ISP+C++ +I Q+GF+
Sbjct: 455 LKCADICNPCRIWEMSKQWSERVCEEFYRQGELEQKFELEISPLCNQQKDSIPSIQIGFM 514
Query: 434 DYIVHPLWETWADLVHPD--AQDILDTLEENRDYYQSMI 544
YIV PL+ WA ++++L L N+ ++S++
Sbjct: 515 SYIVEPLFREWAHFTGNSTLSENMLGHLAHNKAQWKSLL 553
>AB038040-1|BAA96537.1| 450|Homo sapiens cyclic nucleotide
phosphodiesterase 7B protein.
Length = 450
Score = 90.6 bits (215), Expect = 3e-18
Identities = 46/159 (28%), Positives = 90/159 (56%), Gaps = 2/159 (1%)
Frame = +2
Query: 74 EEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENL 253
+E Q + + + ++L+TD+++ L LK + K L L++ DR +L+
Sbjct: 265 KEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKD------LRLEDAQDRHFMLQIA 318
Query: 254 VHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATIEKSQVGFI 433
+ CAD+ NP + + K+W + EEF++QG+ E++ ++ISP+C++ +I Q+GF+
Sbjct: 319 LKCADICNPCRIWEMSKQWSERVCEEFYRQGELEQKFELEISPLCNQQKDSIPSIQIGFM 378
Query: 434 DYIVHPLWETWADLVHPD--AQDILDTLEENRDYYQSMI 544
YIV PL+ WA ++++L L N+ ++S++
Sbjct: 379 SYIVEPLFREWAHFTGNSTLSENMLGHLAHNKAQWKSLL 417
>AK127365-1|BAC86945.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ45439 fis, clone BRSSN2004710, highly similar
to cAMP-dependent 3',5'-cyclic phosphodiesterase 4B (EC
3.1.4.17). ).
Length = 129
Score = 89.4 bits (212), Expect = 7e-18
Identities = 38/42 (90%), Positives = 41/42 (97%)
Frame = +2
Query: 419 QVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
QVGFIDYIVHPLWETWADLV PDAQDILDTLE+NR++YQSMI
Sbjct: 8 QVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMI 49
>AC068499-2|AAF67386.1| 115|Homo sapiens PDE4C [amino acids
597-712] protein.
Length = 115
Score = 86.2 bits (204), Expect = 7e-17
Identities = 35/41 (85%), Positives = 39/41 (95%)
Frame = +2
Query: 422 VGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
VGFIDYI HPLWETWADLVHPDAQD+LDTLE+NR++YQS I
Sbjct: 1 VGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKI 41
>AL109687-1|CAB52020.1| 160|Homo sapiens PDE8A; phosphodiesterase
8A protein.
Length = 160
Score = 84.6 bits (200), Expect = 2e-16
Identities = 44/131 (33%), Positives = 71/131 (54%), Gaps = 1/131 (0%)
Frame = +2
Query: 152 LADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEE 331
LA L+ ET K +L +R + L+ CAD+SNP +PL W A + EE
Sbjct: 19 LATLEENGETDKNQEVINTMLRTPENRTLIKRMLIKCADVSNPCRPLQYCIEWAARISEE 78
Query: 332 FFQQGDREREHGMD-ISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDT 508
+F Q D E++ G+ + P+ DR+ +I KSQ+ FIDY + +++ W V D D++
Sbjct: 79 YFSQTDEEKQQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFV--DLPDLMQH 136
Query: 509 LEENRDYYQSM 541
L+ N Y++ +
Sbjct: 137 LDNNFKYWKGL 147
>X95520-1|CAA64774.1| 1112|Homo sapiens cyclic nucleotide
phosphodiesterase protein.
Length = 1112
Score = 81.8 bits (193), Expect = 1e-15
Identities = 45/133 (33%), Positives = 72/133 (54%)
Frame = +2
Query: 68 HEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLE 247
H E +R R +VI+ +L+TD+ KH LA+ + V +G+ N DR+ V +
Sbjct: 876 HVEFKR--FRFLVIEAILATDLKKHFDFLAEFNA--KANDVNSNGIEW-SNENDRLLVCQ 930
Query: 248 NLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATIEKSQVG 427
+ AD++ P K L+ +W ++ EF++QGD E G+ ISP DR + + K Q
Sbjct: 931 VCIKLADINGPAKVRDLHLKWTEGIVNEFYEQGDEEANLGLPISPFMDRSSPQLAKLQES 990
Query: 428 FIDYIVHPLWETW 466
FI +IV PL ++
Sbjct: 991 FITHIVGPLCNSY 1003
>U38178-1|AAC50724.1| 1112|Homo sapiens cyclic nucleotide
phophodiesterase protein.
Length = 1112
Score = 81.8 bits (193), Expect = 1e-15
Identities = 45/133 (33%), Positives = 72/133 (54%)
Frame = +2
Query: 68 HEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLE 247
H E +R R +VI+ +L+TD+ KH LA+ + V +G+ N DR+ V +
Sbjct: 876 HVEFKR--FRFLVIEAILATDLKKHFDFLAEFNA--KANDVNSNGIEW-SNENDRLLVCQ 930
Query: 248 NLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATIEKSQVG 427
+ AD++ P K L+ +W ++ EF++QGD E G+ ISP DR + + K Q
Sbjct: 931 VCIKLADINGPAKVRDLHLKWTEGIVNEFYEQGDEEANLGLPISPFMDRSSPQLAKLQES 990
Query: 428 FIDYIVHPLWETW 466
FI +IV PL ++
Sbjct: 991 FITHIVGPLCNSY 1003
>D50640-1|BAA09306.1| 1112|Homo sapiens phosphodiesterase 3B protein.
Length = 1112
Score = 81.8 bits (193), Expect = 1e-15
Identities = 45/133 (33%), Positives = 72/133 (54%)
Frame = +2
Query: 68 HEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLE 247
H E +R R +VI+ +L+TD+ KH LA+ + V +G+ N DR+ V +
Sbjct: 876 HVEFKR--FRFLVIEAILATDLKKHFDFLAEFNA--KANDVNSNGIEW-SNENDRLLVCQ 930
Query: 248 NLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATIEKSQVG 427
+ AD++ P K L+ +W ++ EF++QGD E G+ ISP DR + + K Q
Sbjct: 931 VCIKLADINGPAKVRDLHLKWTEGIVNEFYEQGDEEANLGLPISPFMDRSSPQLAKLQES 990
Query: 428 FIDYIVHPLWETW 466
FI +IV PL ++
Sbjct: 991 FITHIVGPLCNSY 1003
>BC150307-1|AAI50308.1| 1112|Homo sapiens phosphodiesterase 3B,
cGMP-inhibited protein.
Length = 1112
Score = 81.8 bits (193), Expect = 1e-15
Identities = 45/133 (33%), Positives = 72/133 (54%)
Frame = +2
Query: 68 HEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLE 247
H E +R R +VI+ +L+TD+ KH LA+ + V +G+ N DR+ V +
Sbjct: 876 HVEFKR--FRFLVIEAILATDLKKHFDFLAEFNA--KANDVNSNGIEW-SNENDRLLVCQ 930
Query: 248 NLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATIEKSQVG 427
+ AD++ P K L+ +W ++ EF++QGD E G+ ISP DR + + K Q
Sbjct: 931 VCIKLADINGPAKVRDLHLKWTEGIVNEFYEQGDEEANLGLPISPFMDRSSPQLAKLQES 990
Query: 428 FIDYIVHPLWETW 466
FI +IV PL ++
Sbjct: 991 FITHIVGPLCNSY 1003
>AY459346-1|AAR24292.1| 1112|Homo sapiens cGMP-inhibited cAMP
phophodiesterase protein.
Length = 1112
Score = 81.8 bits (193), Expect = 1e-15
Identities = 45/133 (33%), Positives = 72/133 (54%)
Frame = +2
Query: 68 HEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLE 247
H E +R R +VI+ +L+TD+ KH LA+ + V +G+ N DR+ V +
Sbjct: 876 HVEFKR--FRFLVIEAILATDLKKHFDFLAEFNA--KANDVNSNGIEW-SNENDRLLVCQ 930
Query: 248 NLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATIEKSQVG 427
+ AD++ P K L+ +W ++ EF++QGD E G+ ISP DR + + K Q
Sbjct: 931 VCIKLADINGPAKVRDLHLKWTEGIVNEFYEQGDEEANLGLPISPFMDRSSPQLAKLQES 990
Query: 428 FIDYIVHPLWETW 466
FI +IV PL ++
Sbjct: 991 FITHIVGPLCNSY 1003
>AF332652-1|AAK57640.1| 424|Homo sapiens cAMP-specific cyclic
nucleotide phosphodiesterase PDE7A3 protein.
Length = 424
Score = 80.6 bits (190), Expect = 3e-15
Identities = 47/143 (32%), Positives = 79/143 (55%)
Frame = +2
Query: 14 RVAFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVA 193
R A LL+ G +F +L E RQ + + ++L+TD+S+ L+ ++ ++
Sbjct: 287 RSAVGLLRESG--LFSHL-PLESRQQMETQIGALILATDISRQNEYLSLFRSHLDR---- 339
Query: 194 GSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMD 373
G L L++ R VL+ + CAD+ NP + L K+W + EEFF QGD E+++ +
Sbjct: 340 --GDLCLEDTRHRHLVLQMALKCADICNPCRTWELSKQWSEKVTEEFFHQGDIEKKYHLG 397
Query: 374 ISPMCDRHNATIEKSQVGFIDYI 442
+SP+CDRH +I Q+G Y+
Sbjct: 398 VSPLCDRHTESIANIQIGNYTYL 420
>U67733-1|AAC51320.1| 941|Homo sapiens PDE2A3 protein.
Length = 941
Score = 78.6 bits (185), Expect = 1e-14
Identities = 48/171 (28%), Positives = 90/171 (52%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A +L GC+IF + ++ ++ L ++ D++L+TD++ H+ + DL+ M E
Sbjct: 734 AIAILNTHGCNIFDHFSRKDYQRML-DLMRDIILATDLAHHLRIFKDLQKMAEV------ 786
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS 379
G + R+ + + C DLS+ TK ++ L+ +EFF QGD E+ G
Sbjct: 787 GYDRNNKQHHRLLLCLLMTSC-DLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPM 845
Query: 380 PMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYY 532
M DR A I + Q+ F+++I P+++ DL P A ++ + + NR+++
Sbjct: 846 EMMDREKAYIPELQISFMEHIAMPIYKLLQDL-FPKAAELYERVASNREHW 895
>AY495087-1|AAS75513.1| 932|Homo sapiens cGMP-stimulated
phosphodiesterase 4 protein.
Length = 932
Score = 78.6 bits (185), Expect = 1e-14
Identities = 48/171 (28%), Positives = 90/171 (52%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A +L GC+IF + ++ ++ L ++ D++L+TD++ H+ + DL+ M E
Sbjct: 725 AIAILNTHGCNIFDHFSRKDYQRML-DLMRDIILATDLAHHLRIFKDLQKMAEV------ 777
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS 379
G + R+ + + C DLS+ TK ++ L+ +EFF QGD E+ G
Sbjct: 778 GYDRNNKQHHRLLLCLLMTSC-DLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPM 836
Query: 380 PMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYY 532
M DR A I + Q+ F+++I P+++ DL P A ++ + + NR+++
Sbjct: 837 EMMDREKAYIPELQISFMEHIAMPIYKLLQDL-FPKAAELYERVASNREHW 886
>AK131525-1|BAD18664.1| 685|Homo sapiens protein ( Homo sapiens
cDNA FLJ16750 fis, clone ADRGL2011190, highly similar
to cGMP-dependent 3',5'-cyclic phosphodiesterase (EC
3.1.4.17). ).
Length = 685
Score = 78.6 bits (185), Expect = 1e-14
Identities = 48/171 (28%), Positives = 90/171 (52%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A +L GC+IF + ++ ++ L ++ D++L+TD++ H+ + DL+ M E
Sbjct: 478 AIAILNTHGCNIFDHFSRKDYQRML-DLMRDIILATDLAHHLRIFKDLQKMAEV------ 530
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS 379
G + R+ + + C DLS+ TK ++ L+ +EFF QGD E+ G
Sbjct: 531 GYDRNNKQHHRLLLCLLMTSC-DLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPM 589
Query: 380 PMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYY 532
M DR A I + Q+ F+++I P+++ DL P A ++ + + NR+++
Sbjct: 590 EMMDREKAYIPELQISFMEHIAMPIYKLLQDL-FPKAAELYERVASNREHW 639
>BC040974-1|AAH40974.1| 941|Homo sapiens phosphodiesterase 2A,
cGMP-stimulated protein.
Length = 941
Score = 75.8 bits (178), Expect = 9e-14
Identities = 47/171 (27%), Positives = 89/171 (52%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A +L GC+IF + ++ ++ L ++ D++L+TD++ H+ + DL+ M E
Sbjct: 734 AIAILNTHGCNIFDHFSRKDYQRML-DLMRDIILATDLAHHLRIFKDLQKMAEV------ 786
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDIS 379
G + R+ + + C DLS+ TK ++ L+ +EFF QGD E+ G
Sbjct: 787 GYDRNNKQHHRLLLCLLMTSC-DLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPM 845
Query: 380 PMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYY 532
M DR A I + Q+ F+++I P+++ DL P A ++ + + N +++
Sbjct: 846 EMMDREKAYIPELQISFMEHIAMPIYKLLQDL-FPKAAELYERVASNGEHW 895
>U36798-1|AAB18673.1| 1141|Homo sapiens platelet cGI-PDE protein.
Length = 1141
Score = 73.3 bits (172), Expect = 5e-13
Identities = 43/139 (30%), Positives = 69/139 (49%)
Frame = +2
Query: 50 DIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTD 229
+ +NL E + R +VI+ +L+TD+ KH +A KV + N D
Sbjct: 884 NFLINLDHVEFKH-FRFLVIEAILATDLKKHFDFVAKFNG-----KVNDDVGIDWTNEND 937
Query: 230 RIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATI 409
R+ V + + AD++ P K L+ +W ++ EF++QGD E G+ ISP DR +
Sbjct: 938 RLLVCQMCIKLADINGPAKCKELHLQWTDGIVNEFYEQGDEEASLGLPISPFMDRSAPQL 997
Query: 410 EKSQVGFIDYIVHPLWETW 466
Q FI +IV PL ++
Sbjct: 998 ANLQESFISHIVGPLCNSY 1016
>M91667-1|AAA35912.2| 1141|Homo sapiens cGMP-inhibited cAMP
phosphodiesterase protein.
Length = 1141
Score = 73.3 bits (172), Expect = 5e-13
Identities = 43/139 (30%), Positives = 69/139 (49%)
Frame = +2
Query: 50 DIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTD 229
+ +NL E + R +VI+ +L+TD+ KH +A KV + N D
Sbjct: 884 NFLINLDHVEFKH-FRFLVIEAILATDLKKHFDFVAKFNG-----KVNDDVGIDWTNEND 937
Query: 230 RIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATI 409
R+ V + + AD++ P K L+ +W ++ EF++QGD E G+ ISP DR +
Sbjct: 938 RLLVCQMCIKLADINGPAKCKELHLQWTDGIVNEFYEQGDEEASLGLPISPFMDRSAPQL 997
Query: 410 EKSQVGFIDYIVHPLWETW 466
Q FI +IV PL ++
Sbjct: 998 ANLQESFISHIVGPLCNSY 1016
>BC117371-1|AAI17372.1| 1141|Homo sapiens phosphodiesterase 3A,
cGMP-inhibited protein.
Length = 1141
Score = 73.3 bits (172), Expect = 5e-13
Identities = 43/139 (30%), Positives = 69/139 (49%)
Frame = +2
Query: 50 DIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTD 229
+ +NL E + R +VI+ +L+TD+ KH +A KV + N D
Sbjct: 884 NFLINLDHVEFKH-FRFLVIEAILATDLKKHFDFVAKFNG-----KVNDDVGIDWTNEND 937
Query: 230 RIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATI 409
R+ V + + AD++ P K L+ +W ++ EF++QGD E G+ ISP DR +
Sbjct: 938 RLLVCQMCIKLADINGPAKCKELHLQWTDGIVNEFYEQGDEEASLGLPISPFMDRSAPQL 997
Query: 410 EKSQVGFIDYIVHPLWETW 466
Q FI +IV PL ++
Sbjct: 998 ANLQESFISHIVGPLCNSY 1016
>BC117369-1|AAI17370.1| 1141|Homo sapiens phosphodiesterase 3A,
cGMP-inhibited protein.
Length = 1141
Score = 73.3 bits (172), Expect = 5e-13
Identities = 43/139 (30%), Positives = 69/139 (49%)
Frame = +2
Query: 50 DIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTD 229
+ +NL E + R +VI+ +L+TD+ KH +A KV + N D
Sbjct: 884 NFLINLDHVEFKH-FRFLVIEAILATDLKKHFDFVAKFNG-----KVNDDVGIDWTNEND 937
Query: 230 RIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATI 409
R+ V + + AD++ P K L+ +W ++ EF++QGD E G+ ISP DR +
Sbjct: 938 RLLVCQMCIKLADINGPAKCKELHLQWTDGIVNEFYEQGDEEASLGLPISPFMDRSAPQL 997
Query: 410 EKSQVGFIDYIVHPLWETW 466
Q FI +IV PL ++
Sbjct: 998 ANLQESFISHIVGPLCNSY 1016
>AJ005036-1|CAA06304.1| 1141|Homo sapiens phosphodiesterase 3A
protein.
Length = 1141
Score = 73.3 bits (172), Expect = 5e-13
Identities = 43/139 (30%), Positives = 69/139 (49%)
Frame = +2
Query: 50 DIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTD 229
+ +NL E + R +VI+ +L+TD+ KH +A KV + N D
Sbjct: 884 NFLINLDHVEFKH-FRFLVIEAILATDLKKHFDFVAKFNG-----KVNDDVGIDWTNEND 937
Query: 230 RIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMCDRHNATI 409
R+ V + + AD++ P K L+ +W ++ EF++QGD E G+ ISP DR +
Sbjct: 938 RLLVCQMCIKLADINGPAKCKELHLQWTDGIVNEFYEQGDEEASLGLPISPFMDRSAPQL 997
Query: 410 EKSQVGFIDYIVHPLWETW 466
Q FI +IV PL ++
Sbjct: 998 ANLQESFISHIVGPLCNSY 1016
>D89094-1|BAA28945.1| 875|Homo sapiens 3',5'-cyclic GMP
phosphodiesterase protein.
Length = 875
Score = 66.9 bits (156), Expect = 4e-11
Identities = 52/173 (30%), Positives = 85/173 (49%), Gaps = 2/173 (1%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+L + G I L EE + TL K++ +L+TD++ ++ + ++ +
Sbjct: 692 ILNSPGNQILSGLSIEEYKTTL-KIIKQAILATDLALYIKRRGEFFELIRKNQFN----- 745
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRER-EHGMDISPM 385
L++ + L L+ DLS TKP P+ +R L+ EFF QGDRER E ++ + +
Sbjct: 746 -LEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFFDQGDRERKELNIEPTDL 804
Query: 386 CDRHNAT-IEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+R I QVGFID I L+E V D +LD +NR +Q++
Sbjct: 805 MNREKKNKIPSMQVGFIDAICLQLYEALTH-VSEDCFPLLDGCRKNRQKWQAL 856
>BC126233-1|AAI26234.1| 875|Homo sapiens phosphodiesterase 5A,
cGMP-specific protein.
Length = 875
Score = 66.9 bits (156), Expect = 4e-11
Identities = 52/173 (30%), Positives = 85/173 (49%), Gaps = 2/173 (1%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+L + G I L EE + TL K++ +L+TD++ ++ + ++ +
Sbjct: 692 ILNSPGNQILSGLSIEEYKTTL-KIIKQAILATDLALYIKRRGEFFELIRKNQFN----- 745
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRER-EHGMDISPM 385
L++ + L L+ DLS TKP P+ +R L+ EFF QGDRER E ++ + +
Sbjct: 746 -LEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFFDQGDRERKELNIEPTDL 804
Query: 386 CDRHNAT-IEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+R I QVGFID I L+E V D +LD +NR +Q++
Sbjct: 805 MNREKKNKIPSMQVGFIDAICLQLYEALTH-VSEDCFPLLDGCRKNRQKWQAL 856
>AY264918-1|AAP21809.1| 833|Homo sapiens phosphodiesterase 5A
protein.
Length = 833
Score = 66.9 bits (156), Expect = 4e-11
Identities = 52/173 (30%), Positives = 85/173 (49%), Gaps = 2/173 (1%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+L + G I L EE + TL K++ +L+TD++ ++ + ++ +
Sbjct: 650 ILNSPGNQILSGLSIEEYKTTL-KIIKQAILATDLALYIKRRGEFFELIRKNQFN----- 703
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRER-EHGMDISPM 385
L++ + L L+ DLS TKP P+ +R L+ EFF QGDRER E ++ + +
Sbjct: 704 -LEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFFDQGDRERKELNIEPTDL 762
Query: 386 CDRHNAT-IEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+R I QVGFID I L+E V D +LD +NR +Q++
Sbjct: 763 MNREKKNKIPSMQVGFIDAICLQLYEALTH-VSEDCFPLLDGCRKNRQKWQAL 814
>AJ004865-1|CAA06170.1| 875|Homo sapiens cGMP-binding, cGMP-specific
phosphodiesterase (HSPDE5A1) protein.
Length = 875
Score = 66.9 bits (156), Expect = 4e-11
Identities = 52/173 (30%), Positives = 85/173 (49%), Gaps = 2/173 (1%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+L + G I L EE + TL K++ +L+TD++ ++ + ++ +
Sbjct: 692 ILNSPGNQILSGLSIEEYKTTL-KIIKQAILATDLALYIKRRGEFFELIRKNQFN----- 745
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRER-EHGMDISPM 385
L++ + L L+ DLS TKP P+ +R L+ EFF QGDRER E ++ + +
Sbjct: 746 -LEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFFDQGDRERKELNIEPTDL 804
Query: 386 CDRHNAT-IEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+R I QVGFID I L+E V D +LD +NR +Q++
Sbjct: 805 MNREKKNKIPSMQVGFIDAICLQLYEALTH-VSEDCFPLLDGCRKNRQKWQAL 856
>AF043731-1|AAC63967.1| 875|Homo sapiens cGMP-binding cGMP-specific
3',5'-cyclic nucleotide phosphodiesterase protein.
Length = 875
Score = 66.9 bits (156), Expect = 4e-11
Identities = 52/173 (30%), Positives = 85/173 (49%), Gaps = 2/173 (1%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+L + G I L EE + TL K++ +L+TD++ ++ + ++ +
Sbjct: 692 ILNSPGNQILSGLSIEEYKTTL-KIIKQAILATDLALYIKRRGEFFELIRKNQFN----- 745
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRER-EHGMDISPM 385
L++ + L L+ DLS TKP P+ +R L+ EFF QGDRER E ++ + +
Sbjct: 746 -LEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFFDQGDRERKELNIEPTDL 804
Query: 386 CDRHNAT-IEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+R I QVGFID I L+E V D +LD +NR +Q++
Sbjct: 805 MNREKKNKIPSMQVGFIDAICLQLYEALTH-VSEDCFPLLDGCRKNRQKWQAL 856
>AC093752-1|AAY40985.1| 331|Homo sapiens unknown protein.
Length = 331
Score = 66.9 bits (156), Expect = 4e-11
Identities = 52/173 (30%), Positives = 85/173 (49%), Gaps = 2/173 (1%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+L + G I L EE + TL K++ +L+TD++ ++ + ++ +
Sbjct: 148 ILNSPGNQILSGLSIEEYKTTL-KIIKQAILATDLALYIKRRGEFFELIRKNQFN----- 201
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRER-EHGMDISPM 385
L++ + L L+ DLS TKP P+ +R L+ EFF QGDRER E ++ + +
Sbjct: 202 -LEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFFDQGDRERKELNIEPTDL 260
Query: 386 CDRHNAT-IEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+R I QVGFID I L+E V D +LD +NR +Q++
Sbjct: 261 MNREKKNKIPSMQVGFIDAICLQLYEALTH-VSEDCFPLLDGCRKNRQKWQAL 312
>AB015656-1|BAA81667.1| 833|Homo sapiens cGMP-binding cGMP specific
phosphodiesterase 5A2 protein.
Length = 833
Score = 66.9 bits (156), Expect = 4e-11
Identities = 52/173 (30%), Positives = 85/173 (49%), Gaps = 2/173 (1%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+L + G I L EE + TL K++ +L+TD++ ++ + ++ +
Sbjct: 650 ILNSPGNQILSGLSIEEYKTTL-KIIKQAILATDLALYIKRRGEFFELIRKNQFN----- 703
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRER-EHGMDISPM 385
L++ + L L+ DLS TKP P+ +R L+ EFF QGDRER E ++ + +
Sbjct: 704 -LEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFFDQGDRERKELNIEPTDL 762
Query: 386 CDRHNAT-IEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+R I QVGFID I L+E V D +LD +NR +Q++
Sbjct: 763 MNREKKNKIPSMQVGFIDAICLQLYEALTH-VSEDCFPLLDGCRKNRQKWQAL 814
>AB001635-1|BAA33372.2| 875|Homo sapiens cGMP-binding cGMP-specific
phosphodiesterase protein.
Length = 875
Score = 66.9 bits (156), Expect = 4e-11
Identities = 52/173 (30%), Positives = 85/173 (49%), Gaps = 2/173 (1%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+L + G I L EE + TL K++ +L+TD++ ++ + ++ +
Sbjct: 692 ILNSPGNQILSGLSIEEYKTTL-KIIKQAILATDLALYIKRRGEFFELIRKNQFN----- 745
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRER-EHGMDISPM 385
L++ + L L+ DLS TKP P+ +R L+ EFF QGDRER E ++ + +
Sbjct: 746 -LEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFFDQGDRERKELNIEPTDL 804
Query: 386 CDRHNAT-IEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+R I QVGFID I L+E V D +LD +NR +Q++
Sbjct: 805 MNREKKNKIPSMQVGFIDAICLQLYEALTH-VSEDCFPLLDGCRKNRQKWQAL 856
>CR536567-1|CAG38804.1| 779|Homo sapiens PDE10A protein.
Length = 779
Score = 64.5 bits (150), Expect = 2e-10
Identities = 44/173 (25%), Positives = 86/173 (49%), Gaps = 1/173 (0%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+LQ +G +IF L E Q L +++ +++TD++ + L+ M +T G L
Sbjct: 592 ILQLEGHNIFSTLSSSEYEQVL-EIIRKAIIATDLALYFGNRKQLEEMYQT------GSL 644
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMC 388
L+N + R +V+ ++ DL + TK P+ K + EF+ +GD ++ G+ PM
Sbjct: 645 NLNNQSHRDRVISLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMM 704
Query: 389 DRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
DR + + Q+GF + + P + T ++ P + +L +N ++ +I
Sbjct: 705 DRDKKDEVPQGQLGFYNAVAIPCYTTLTQIL-PPTEPLLKACRDNLSQWEKVI 756
>BC104860-1|AAI04861.1| 779|Homo sapiens phosphodiesterase 10A
protein.
Length = 779
Score = 63.7 bits (148), Expect = 4e-10
Identities = 44/173 (25%), Positives = 86/173 (49%), Gaps = 1/173 (0%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+LQ +G +IF L E Q L +++ +++TD++ + L+ M +T G L
Sbjct: 592 ILQLEGHNIFSTLSSSEYEQVL-EIIRKAIIATDLALYFGNRKQLEEMYQT------GSL 644
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMC 388
L+N + R +V+ ++ DL + TK P+ K + EF+ +GD ++ G+ PM
Sbjct: 645 NLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMM 704
Query: 389 DRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
DR + + Q+GF + + P + T ++ P + +L +N ++ +I
Sbjct: 705 DRDKKDEVPQGQLGFYNAVAIPCYTTLTQIL-PPTEPLLKACRDNLSQWEKVI 756
>BC104858-1|AAI04859.1| 779|Homo sapiens phosphodiesterase 10A
protein.
Length = 779
Score = 63.7 bits (148), Expect = 4e-10
Identities = 44/173 (25%), Positives = 86/173 (49%), Gaps = 1/173 (0%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+LQ +G +IF L E Q L +++ +++TD++ + L+ M +T G L
Sbjct: 592 ILQLEGHNIFSTLSSSEYEQVL-EIIRKAIIATDLALYFGNRKQLEEMYQT------GSL 644
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMC 388
L+N + R +V+ ++ DL + TK P+ K + EF+ +GD ++ G+ PM
Sbjct: 645 NLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMM 704
Query: 389 DRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
DR + + Q+GF + + P + T ++ P + +L +N ++ +I
Sbjct: 705 DRDKKDEVPQGQLGFYNAVAIPCYTTLTQIL-PPTEPLLKACRDNLSQWEKVI 756
>AL160160-1|CAH72023.1| 779|Homo sapiens phosphodiesterase 10A
protein.
Length = 779
Score = 63.7 bits (148), Expect = 4e-10
Identities = 44/173 (25%), Positives = 86/173 (49%), Gaps = 1/173 (0%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+LQ +G +IF L E Q L +++ +++TD++ + L+ M +T G L
Sbjct: 592 ILQLEGHNIFSTLSSSEYEQVL-EIIRKAIIATDLALYFGNRKQLEEMYQT------GSL 644
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMC 388
L+N + R +V+ ++ DL + TK P+ K + EF+ +GD ++ G+ PM
Sbjct: 645 NLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMM 704
Query: 389 DRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
DR + + Q+GF + + P + T ++ P + +L +N ++ +I
Sbjct: 705 DRDKKDEVPQGQLGFYNAVAIPCYTTLTQIL-PPTEPLLKACRDNLSQWEKVI 756
>AL136130-1|CAI20436.1| 779|Homo sapiens phosphodiesterase 10A
protein.
Length = 779
Score = 63.7 bits (148), Expect = 4e-10
Identities = 44/173 (25%), Positives = 86/173 (49%), Gaps = 1/173 (0%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+LQ +G +IF L E Q L +++ +++TD++ + L+ M +T G L
Sbjct: 592 ILQLEGHNIFSTLSSSEYEQVL-EIIRKAIIATDLALYFGNRKQLEEMYQT------GSL 644
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMC 388
L+N + R +V+ ++ DL + TK P+ K + EF+ +GD ++ G+ PM
Sbjct: 645 NLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMM 704
Query: 389 DRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
DR + + Q+GF + + P + T ++ P + +L +N ++ +I
Sbjct: 705 DRDKKDEVPQGQLGFYNAVAIPCYTTLTQIL-PPTEPLLKACRDNLSQWEKVI 756
>AL117345-1|CAB92797.2| 779|Homo sapiens phosphodiesterase 10A
protein.
Length = 779
Score = 63.7 bits (148), Expect = 4e-10
Identities = 44/173 (25%), Positives = 86/173 (49%), Gaps = 1/173 (0%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+LQ +G +IF L E Q L +++ +++TD++ + L+ M +T G L
Sbjct: 592 ILQLEGHNIFSTLSSSEYEQVL-EIIRKAIIATDLALYFGNRKQLEEMYQT------GSL 644
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMC 388
L+N + R +V+ ++ DL + TK P+ K + EF+ +GD ++ G+ PM
Sbjct: 645 NLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMM 704
Query: 389 DRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
DR + + Q+GF + + P + T ++ P + +L +N ++ +I
Sbjct: 705 DRDKKDEVPQGQLGFYNAVAIPCYTTLTQIL-PPTEPLLKACRDNLSQWEKVI 756
>AF127480-1|AAD32596.1| 807|Homo sapiens 3',5'-cyclic nucleotide
phosphodiesterase 10A2 protein.
Length = 807
Score = 63.7 bits (148), Expect = 4e-10
Identities = 44/173 (25%), Positives = 86/173 (49%), Gaps = 1/173 (0%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+LQ +G +IF L E Q L +++ +++TD++ + L+ M +T G L
Sbjct: 620 ILQLEGHNIFSTLSSSEYEQVL-EIIRKAIIATDLALYFGNRKQLEEMYQT------GSL 672
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMC 388
L+N + R +V+ ++ DL + TK P+ K + EF+ +GD ++ G+ PM
Sbjct: 673 NLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMM 732
Query: 389 DRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
DR + + Q+GF + + P + T ++ P + +L +N ++ +I
Sbjct: 733 DRDKKDEVPQGQLGFYNAVAIPCYTTLTQIL-PPTEPLLKACRDNLSQWEKVI 784
>AF127479-1|AAD32595.1| 779|Homo sapiens 3',5'-cyclic nucleotide
phosphodiesterase 10A1 protein.
Length = 779
Score = 63.7 bits (148), Expect = 4e-10
Identities = 44/173 (25%), Positives = 86/173 (49%), Gaps = 1/173 (0%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+LQ +G +IF L E Q L +++ +++TD++ + L+ M +T G L
Sbjct: 592 ILQLEGHNIFSTLSSSEYEQVL-EIIRKAIIATDLALYFGNRKQLEEMYQT------GSL 644
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMC 388
L+N + R +V+ ++ DL + TK P+ K + EF+ +GD ++ G+ PM
Sbjct: 645 NLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMM 704
Query: 389 DRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
DR + + Q+GF + + P + T ++ P + +L +N ++ +I
Sbjct: 705 DRDKKDEVPQGQLGFYNAVAIPCYTTLTQIL-PPTEPLLKACRDNLSQWEKVI 756
>AB041798-3|BAB16383.1| 714|Homo sapiens phosphodiesterase 10A1
(PDE10A1) protein.
Length = 714
Score = 63.7 bits (148), Expect = 4e-10
Identities = 44/173 (25%), Positives = 86/173 (49%), Gaps = 1/173 (0%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+LQ +G +IF L E Q L +++ +++TD++ + L+ M +T G L
Sbjct: 527 ILQLEGHNIFSTLSSSEYEQVL-EIIRKAIIATDLALYFGNRKQLEEMYQT------GSL 579
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMC 388
L+N + R +V+ ++ DL + TK P+ K + EF+ +GD ++ G+ PM
Sbjct: 580 NLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMM 639
Query: 389 DRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
DR + + Q+GF + + P + T ++ P + +L +N ++ +I
Sbjct: 640 DRDKKDEVPQGQLGFYNAVAIPCYTTLTQIL-PPTEPLLKACRDNLSQWEKVI 691
>AB026816-1|BAA84467.1| 789|Homo sapiens 3',5'-cyclic nucleotide
phosphodiesterase 10A2 protein.
Length = 789
Score = 63.7 bits (148), Expect = 4e-10
Identities = 44/173 (25%), Positives = 86/173 (49%), Gaps = 1/173 (0%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+LQ +G +IF L E Q L +++ +++TD++ + L+ M +T G L
Sbjct: 602 ILQLEGHNIFSTLSSSEYEQVL-EIIRKAIIATDLALYFGNRKQLEEMYQT------GSL 654
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMC 388
L+N + R +V+ ++ DL + TK P+ K + EF+ +GD ++ G+ PM
Sbjct: 655 NLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMM 714
Query: 389 DRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
DR + + Q+GF + + P + T ++ P + +L +N ++ +I
Sbjct: 715 DRDKKDEVPQGQLGFYNAVAIPCYTTLTQIL-PPTEPLLKACRDNLSQWEKVI 766
>AB020593-1|BAA78034.1| 779|Homo sapiens 3',5'-Cyclic nucleotide
phosphodiesterase protein.
Length = 779
Score = 63.7 bits (148), Expect = 4e-10
Identities = 44/173 (25%), Positives = 86/173 (49%), Gaps = 1/173 (0%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSGVL 208
+LQ +G +IF L E Q L +++ +++TD++ + L+ M +T G L
Sbjct: 592 ILQLEGHNIFSTLSSSEYEQVL-EIIRKAIIATDLALYFGNRKQLEEMYQT------GSL 644
Query: 209 LLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDREREHGMDISPMC 388
L+N + R +V+ ++ DL + TK P+ K + EF+ +GD ++ G+ PM
Sbjct: 645 NLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMM 704
Query: 389 DRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 544
DR + + Q+GF + + P + T ++ P + +L +N ++ +I
Sbjct: 705 DRDKKDEVPQGQLGFYNAVAIPCYTTLTQIL-PPTEPLLKACRDNLSQWEKVI 756
>X62692-1|CAA44569.1| 854|Homo sapiens cGMP phosphodiesterase beta
subunit protein.
Length = 854
Score = 63.3 bits (147), Expect = 5e-10
Identities = 49/177 (27%), Positives = 91/177 (51%), Gaps = 6/177 (3%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKV---AGS 199
LL + +I+ NL+ + + M I +++TD++ + A + +V+ K S
Sbjct: 636 LLSEETLNIYQNLNRRQHEHVIHLMDI-AIIATDLALYFKKRAMFQKIVDESKNYQDKKS 694
Query: 200 GVLLLDNYTDRIQVLENLVHCA-DLSNPTKPLPLYKRWVALLMEEFFQQGDRERE-HGMD 373
V +L T R +++ ++ A DLS TKP + + L+ EF++QGD ER
Sbjct: 695 WVEILSLETTRKEIVMAMMMTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLDQQ 754
Query: 374 ISPMCDRHNAT-IEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
PM DR+ A + K QVGFID++ +++ ++ H + + D L+ NR ++++
Sbjct: 755 PIPMMDRNKAAELPKLQVGFIDFVCTFVYKEFSRF-HEEILPMFDRLQNNRKEWKAL 810
>M26061-1|AAB69155.1| 860|Homo sapiens PDEA protein.
Length = 860
Score = 62.5 bits (145), Expect = 9e-10
Identities = 47/178 (26%), Positives = 91/178 (51%), Gaps = 7/178 (3%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSG-- 202
LL+++ +IF NL+ + + M I +++TD++ + + +V+ K S
Sbjct: 638 LLRDESLNIFQNLNRRQHEHAIHMMDI-AIIATDLALYFKKRTMFQKIVDQSKTYESEQE 696
Query: 203 ---VLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRERE-HGM 370
++L+ I V+ ++ DLS TKP + + L+ EF++QGD ER
Sbjct: 697 WTQYMMLEQTRKEI-VMAMMMTACDLSAITKPWEVQSQVALLVAAEFWEQGDLERTVLQQ 755
Query: 371 DISPMCDRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+ PM DR+ A + K QVGFID++ +++ ++ H + +LD + NR ++++
Sbjct: 756 NPIPMMDRNKADELPKLQVGFIDFVCTFVYKEFSRF-HEEITPMLDGITNNRKEWKAL 812
>BC035909-1|AAH35909.1| 860|Homo sapiens phosphodiesterase 6A,
cGMP-specific, rod, alpha protein.
Length = 860
Score = 62.5 bits (145), Expect = 9e-10
Identities = 47/178 (26%), Positives = 91/178 (51%), Gaps = 7/178 (3%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSG-- 202
LL+++ +IF NL+ + + M I +++TD++ + + +V+ K S
Sbjct: 638 LLRDESLNIFQNLNRRQHEHAIHMMDI-AIIATDLALYFKKRTMFQKIVDQSKTYESEQE 696
Query: 203 ---VLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRERE-HGM 370
++L+ I V+ ++ DLS TKP + + L+ EF++QGD ER
Sbjct: 697 WTQYMMLEQTRKEI-VMAMMMTACDLSAITKPWEVQSQVALLVAAEFWEQGDLERTVLQQ 755
Query: 371 DISPMCDRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+ PM DR+ A + K QVGFID++ +++ ++ H + +LD + NR ++++
Sbjct: 756 NPIPMMDRNKADELPKLQVGFIDFVCTFVYKEFSRF-HEEITPMLDGITNNRKEWKAL 812
>X90587-1|CAA62215.1| 617|Homo sapiens Rod cGMP phosphodiesterase
protein.
Length = 617
Score = 62.1 bits (144), Expect = 1e-09
Identities = 49/177 (27%), Positives = 90/177 (50%), Gaps = 6/177 (3%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKV---AGS 199
LL + +I+ NL+ + + M I +++TD++ + A + +V+ K S
Sbjct: 399 LLSEETLNIYQNLNRRQHEHVIHLMDI-AIIATDLALYFKKRAMFQKIVDESKNYQDKKS 457
Query: 200 GVLLLDNYTDRIQVLENLVHCA-DLSNPTKPLPLYKRWVALLMEEFFQQGDRERE-HGMD 373
V L T R +++ ++ A DLS TKP + + L+ EF++QGD ER
Sbjct: 458 WVEYLSLETTRKEIVMAMMMTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLDQQ 517
Query: 374 ISPMCDRHNAT-IEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
PM DR+ A + K QVGFID++ +++ ++ H + + D L+ NR ++++
Sbjct: 518 PIPMMDRNKAAELPKLQVGFIDFVCTFVYKEFSRF-HEEILPMFDRLQNNRKEWKAL 573
>X66142-1|CAA46932.1| 854|Homo sapiens 3',5'-cyclic-nucleotide
phosphodiesterase protein.
Length = 854
Score = 62.1 bits (144), Expect = 1e-09
Identities = 49/177 (27%), Positives = 90/177 (50%), Gaps = 6/177 (3%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKV---AGS 199
LL + +I+ NL+ + + M I +++TD++ + A + +V+ K S
Sbjct: 636 LLSEETLNIYQNLNRRQHEHVIHLMDI-AIIATDLALYFKKRAMFQKIVDESKNYQDKKS 694
Query: 200 GVLLLDNYTDRIQVLENLVHCA-DLSNPTKPLPLYKRWVALLMEEFFQQGDRERE-HGMD 373
V L T R +++ ++ A DLS TKP + + L+ EF++QGD ER
Sbjct: 695 WVEYLSLETTRKEIVMAMMMTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLDQQ 754
Query: 374 ISPMCDRHNAT-IEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
PM DR+ A + K QVGFID++ +++ ++ H + + D L+ NR ++++
Sbjct: 755 PIPMMDRNKAAELPKLQVGFIDFVCTFVYKEFSRF-HEEILPMFDRLQNNRKEWKAL 810
>S41458-1|AAB22690.1| 854|Homo sapiens rod cGMP phosphodiesterase
beta-subunit protein.
Length = 854
Score = 62.1 bits (144), Expect = 1e-09
Identities = 49/177 (27%), Positives = 90/177 (50%), Gaps = 6/177 (3%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKV---AGS 199
LL + +I+ NL+ + + M I +++TD++ + A + +V+ K S
Sbjct: 636 LLSEETLNIYQNLNRRQHEHVIHLMDI-AIIATDLALYFKKRAMFQKIVDESKNYQDKKS 694
Query: 200 GVLLLDNYTDRIQVLENLVHCA-DLSNPTKPLPLYKRWVALLMEEFFQQGDRERE-HGMD 373
V L T R +++ ++ A DLS TKP + + L+ EF++QGD ER
Sbjct: 695 WVEYLSLETTRKEIVMAMMMTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLDQQ 754
Query: 374 ISPMCDRHNAT-IEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
PM DR+ A + K QVGFID++ +++ ++ H + + D L+ NR ++++
Sbjct: 755 PIPMMDRNKAAELPKLQVGFIDFVCTFVYKEFSRF-HEEILPMFDRLQNNRKEWKAL 810
>BT009794-1|AAP88796.1| 853|Homo sapiens phosphodiesterase 6B,
cGMP-specific, rod, beta (congenital stationary night bli
protein.
Length = 853
Score = 61.3 bits (142), Expect = 2e-09
Identities = 49/177 (27%), Positives = 90/177 (50%), Gaps = 6/177 (3%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKV---AGS 199
LL + +I+ NL+ + + M I +++TD++ + A + +V+ K S
Sbjct: 636 LLSEETLNIYQNLNRRQHDHVIHLMDI-AIIATDLALYFKKRAMFQKIVDESKNYQDKKS 694
Query: 200 GVLLLDNYTDRIQVLENLVHCA-DLSNPTKPLPLYKRWVALLMEEFFQQGDRERE-HGMD 373
V L T R +++ ++ A DLS TKP + + L+ EF++QGD ER
Sbjct: 695 WVEYLSLETTRKEIVMAMMMTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLDQQ 754
Query: 374 ISPMCDRHNAT-IEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
PM DR+ A + K QVGFID++ +++ ++ H + + D L+ NR ++++
Sbjct: 755 PIPMMDRNKAAELPKLQVGFIDFVCTFVYKEFSRF-HEEILPMFDRLQNNRKEWKAL 810
>BC000249-1|AAH00249.1| 853|Homo sapiens phosphodiesterase 6B,
cGMP-specific, rod, beta (congenital stationary night bli
protein.
Length = 853
Score = 61.3 bits (142), Expect = 2e-09
Identities = 49/177 (27%), Positives = 90/177 (50%), Gaps = 6/177 (3%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKV---AGS 199
LL + +I+ NL+ + + M I +++TD++ + A + +V+ K S
Sbjct: 636 LLSEETLNIYQNLNRRQHDHVIHLMDI-AIIATDLALYFKKRAMFQKIVDESKNYQDKKS 694
Query: 200 GVLLLDNYTDRIQVLENLVHCA-DLSNPTKPLPLYKRWVALLMEEFFQQGDRERE-HGMD 373
V L T R +++ ++ A DLS TKP + + L+ EF++QGD ER
Sbjct: 695 WVEYLSLETTRKEIVMAMMMTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLDQQ 754
Query: 374 ISPMCDRHNAT-IEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
PM DR+ A + K QVGFID++ +++ ++ H + + D L+ NR ++++
Sbjct: 755 PIPMMDRNKAAELPKLQVGFIDFVCTFVYKEFSRF-HEEILPMFDRLQNNRKEWKAL 810
>BC114431-1|AAI14432.1| 934|Homo sapiens phosphodiesterase 11A
protein.
Length = 934
Score = 60.9 bits (141), Expect = 3e-09
Identities = 47/176 (26%), Positives = 91/176 (51%), Gaps = 2/176 (1%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A +LQ++G +IF NL +E L +++ +L+TD++ + + +V + +
Sbjct: 741 AVMILQSEGHNIFANLSSKEYSD-LMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWN 799
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRER-EHGMDI 376
+ N+ D + + L+ DL TKP + ++ L+ EFF+QGDRER E +
Sbjct: 800 ----IKNHRDIFRSM--LMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTP 853
Query: 377 SPMCDRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
S + DR+ + + Q+ +ID I PL++ V+ + +LD++ NR ++ +
Sbjct: 854 SAIFDRNRKDELPRLQLEWIDSICMPLYQALVK-VNVKLKPMLDSVATNRSKWEEL 908
>BC112393-1|AAI12394.1| 934|Homo sapiens phosphodiesterase 11A
protein.
Length = 934
Score = 60.9 bits (141), Expect = 3e-09
Identities = 47/176 (26%), Positives = 91/176 (51%), Gaps = 2/176 (1%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A +LQ++G +IF NL +E L +++ +L+TD++ + + +V + +
Sbjct: 741 AVMILQSEGHNIFANLSSKEYSD-LMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWN 799
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRER-EHGMDI 376
+ N+ D + + L+ DL TKP + ++ L+ EFF+QGDRER E +
Sbjct: 800 ----IKNHRDIFRSM--LMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTP 853
Query: 377 SPMCDRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
S + DR+ + + Q+ +ID I PL++ V+ + +LD++ NR ++ +
Sbjct: 854 SAIFDRNRKDELPRLQLEWIDSICMPLYQALVK-VNVKLKPMLDSVATNRSKWEEL 908
>AJ278682-1|CAC15567.1| 684|Homo sapiens cAMP/cGMP cyclic
nucleotide phosphodiesterase 11A3 protein.
Length = 684
Score = 60.9 bits (141), Expect = 3e-09
Identities = 47/176 (26%), Positives = 91/176 (51%), Gaps = 2/176 (1%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A +LQ++G +IF NL +E L +++ +L+TD++ + + +V + +
Sbjct: 491 AVMILQSEGHNIFANLSSKEYSD-LMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWN 549
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRER-EHGMDI 376
+ N+ D + + L+ DL TKP + ++ L+ EFF+QGDRER E +
Sbjct: 550 ----IKNHRDIFRSM--LMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTP 603
Query: 377 SPMCDRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
S + DR+ + + Q+ +ID I PL++ V+ + +LD++ NR ++ +
Sbjct: 604 SAIFDRNRKDELPRLQLEWIDSICMPLYQALVK-VNVKLKPMLDSVATNRSKWEEL 658
>AJ251509-1|CAB82573.1| 490|Homo sapiens cyclic nucleotide
phosphodiesterase 11A1 protein.
Length = 490
Score = 60.9 bits (141), Expect = 3e-09
Identities = 47/176 (26%), Positives = 91/176 (51%), Gaps = 2/176 (1%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A +LQ++G +IF NL +E L +++ +L+TD++ + + +V + +
Sbjct: 297 AVMILQSEGHNIFANLSSKEYSD-LMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWN 355
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRER-EHGMDI 376
+ N+ D + + L+ DL TKP + ++ L+ EFF+QGDRER E +
Sbjct: 356 ----IKNHRDIFRSM--LMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTP 409
Query: 377 SPMCDRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
S + DR+ + + Q+ +ID I PL++ V+ + +LD++ NR ++ +
Sbjct: 410 SAIFDRNRKDELPRLQLEWIDSICMPLYQALVK-VNVKLKPMLDSVATNRSKWEEL 464
>AF281865-1|AAG32023.1| 576|Homo sapiens cAMP/cGMP
phosphodiesterase 11A2 protein.
Length = 576
Score = 60.9 bits (141), Expect = 3e-09
Identities = 47/176 (26%), Positives = 91/176 (51%), Gaps = 2/176 (1%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A +LQ++G +IF NL +E L +++ +L+TD++ + + +V + +
Sbjct: 383 AVMILQSEGHNIFANLSSKEYSD-LMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWN 441
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRER-EHGMDI 376
+ N+ D + + L+ DL TKP + ++ L+ EFF+QGDRER E +
Sbjct: 442 ----IKNHRDIFRSM--LMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTP 495
Query: 377 SPMCDRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
S + DR+ + + Q+ +ID I PL++ V+ + +LD++ NR ++ +
Sbjct: 496 SAIFDRNRKDELPRLQLEWIDSICMPLYQALVK-VNVKLKPMLDSVATNRSKWEEL 550
>AB048423-3|BAB62714.1| 490|Homo sapiens phosphodiesterase 11A1
protein.
Length = 490
Score = 60.9 bits (141), Expect = 3e-09
Identities = 47/176 (26%), Positives = 91/176 (51%), Gaps = 2/176 (1%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A +LQ++G +IF NL +E L +++ +L+TD++ + + +V + +
Sbjct: 297 AVMILQSEGHNIFANLSSKEYSD-LMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWN 355
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRER-EHGMDI 376
+ N+ D + + L+ DL TKP + ++ L+ EFF+QGDRER E +
Sbjct: 356 ----IKNHRDIFRSM--LMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTP 409
Query: 377 SPMCDRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
S + DR+ + + Q+ +ID I PL++ V+ + +LD++ NR ++ +
Sbjct: 410 SAIFDRNRKDELPRLQLEWIDSICMPLYQALVK-VNVKLKPMLDSVATNRSKWEEL 464
>AB048423-2|BAB62712.1| 934|Homo sapiens phosphodiesterase 11A4
protein.
Length = 934
Score = 60.9 bits (141), Expect = 3e-09
Identities = 47/176 (26%), Positives = 91/176 (51%), Gaps = 2/176 (1%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A +LQ++G +IF NL +E L +++ +L+TD++ + + +V + +
Sbjct: 741 AVMILQSEGHNIFANLSSKEYSD-LMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWN 799
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRER-EHGMDI 376
+ N+ D + + L+ DL TKP + ++ L+ EFF+QGDRER E +
Sbjct: 800 ----IKNHRDIFRSM--LMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTP 853
Query: 377 SPMCDRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
S + DR+ + + Q+ +ID I PL++ V+ + +LD++ NR ++ +
Sbjct: 854 SAIFDRNRKDELPRLQLEWIDSICMPLYQALVK-VNVKLKPMLDSVATNRSKWEEL 908
>AB048423-1|BAB62713.2| 684|Homo sapiens phosphodiesterase 11A3
protein.
Length = 684
Score = 60.9 bits (141), Expect = 3e-09
Identities = 47/176 (26%), Positives = 91/176 (51%), Gaps = 2/176 (1%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A +LQ++G +IF NL +E L +++ +L+TD++ + + +V + +
Sbjct: 491 AVMILQSEGHNIFANLSSKEYSD-LMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWN 549
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRER-EHGMDI 376
+ N+ D + + L+ DL TKP + ++ L+ EFF+QGDRER E +
Sbjct: 550 ----IKNHRDIFRSM--LMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTP 603
Query: 377 SPMCDRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
S + DR+ + + Q+ +ID I PL++ V+ + +LD++ NR ++ +
Sbjct: 604 SAIFDRNRKDELPRLQLEWIDSICMPLYQALVK-VNVKLKPMLDSVATNRSKWEEL 658
>AB038041-1|BAB16372.1| 684|Homo sapiens phosphodiesterase 11A3
protein.
Length = 684
Score = 60.9 bits (141), Expect = 3e-09
Identities = 47/176 (26%), Positives = 91/176 (51%), Gaps = 2/176 (1%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A +LQ++G +IF NL +E L +++ +L+TD++ + + +V + +
Sbjct: 491 AVMILQSEGHNIFANLSSKEYSD-LMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWN 549
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRER-EHGMDI 376
+ N+ D + + L+ DL TKP + ++ L+ EFF+QGDRER E +
Sbjct: 550 ----IKNHRDIFRSM--LMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTP 603
Query: 377 SPMCDRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
S + DR+ + + Q+ +ID I PL++ V+ + +LD++ NR ++ +
Sbjct: 604 SAIFDRNRKDELPRLQLEWIDSICMPLYQALVK-VNVKLKPMLDSVATNRSKWEEL 658
>AB036704-1|BAB16371.1| 934|Homo sapiens phosphodiesterase 11A
protein.
Length = 934
Score = 60.9 bits (141), Expect = 3e-09
Identities = 47/176 (26%), Positives = 91/176 (51%), Gaps = 2/176 (1%)
Frame = +2
Query: 20 AFKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGS 199
A +LQ++G +IF NL +E L +++ +L+TD++ + + +V + +
Sbjct: 741 AVMILQSEGHNIFANLSSKEYSD-LMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWN 799
Query: 200 GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRER-EHGMDI 376
+ N+ D + + L+ DL TKP + ++ L+ EFF+QGDRER E +
Sbjct: 800 ----IKNHRDIFRSM--LMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTP 853
Query: 377 SPMCDRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
S + DR+ + + Q+ +ID I PL++ V+ + +LD++ NR ++ +
Sbjct: 854 SAIFDRNRKDELPRLQLEWIDSICMPLYQALVK-VNVKLKPMLDSVATNRSKWEEL 908
>U40584-1|AAB50018.1| 184|Homo sapiens
calcium/calmodulin-stimulated cyclic nucleotide
phosphodiesterase protein.
Length = 184
Score = 60.5 bits (140), Expect = 4e-09
Identities = 35/96 (36%), Positives = 58/96 (60%)
Frame = +2
Query: 23 FKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSLLADLKTMVETKKVAGSG 202
F+L+Q+D +IF+NL ++E + LR +VI+MVL+TDMS H + +KT ++ +
Sbjct: 101 FRLMQDDEMNIFINLTKDEFVE-LRALVIEMVLATDMSCHFQQVKTMKTALQQLE----- 154
Query: 203 VLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRW 310
D+ + L L+H AD+S+PTK ++ RW
Sbjct: 155 ------RIDKSKALSLLLHAADISHPTKQWLVHSRW 184
>X94354-1|CAA64079.1| 858|Homo sapiens cone cGMP phosphodiesterase
protein.
Length = 858
Score = 55.2 bits (127), Expect = 1e-07
Identities = 46/179 (25%), Positives = 93/179 (51%), Gaps = 8/179 (4%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSL------LADLKTMVETKKV 190
LLQ++ +IF NL++ Q +T+ + +++TD++ + + D ++T++
Sbjct: 641 LLQDESLNIFQNLNKR-QFETVIHLFEVAIIATDLALYFKKRTMFQKIVDACEQMQTEEE 699
Query: 191 AGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRERE-HG 367
A V + + T + ++ ++ DLS TKP + + ++ EF++QGD ER
Sbjct: 700 AIKYVTV--DPTKKEIIMAMMMTACDLSAITKPWEVQSQVALMVANEFWEQGDLERTVLQ 757
Query: 368 MDISPMCDRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
PM DR+ + K QVGFID++ +++ ++ H + +L L+ NR ++S+
Sbjct: 758 QQPIPMMDRNKRDELPKLQVGFIDFVCTFVYKEFSRF-HKEITPMLSGLQNNRVEWKSL 815
>U31973-1|AAA96392.1| 858|Homo sapiens phosphodiesterase A' subunit
protein.
Length = 858
Score = 55.2 bits (127), Expect = 1e-07
Identities = 46/179 (25%), Positives = 93/179 (51%), Gaps = 8/179 (4%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSL------LADLKTMVETKKV 190
LLQ++ +IF NL++ Q +T+ + +++TD++ + + D ++T++
Sbjct: 641 LLQDESLNIFQNLNKR-QFETVIHLFEVAIIATDLALYFKKRTMFQKIVDACEQMQTEEE 699
Query: 191 AGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRERE-HG 367
A V + + T + ++ ++ DLS TKP + + ++ EF++QGD ER
Sbjct: 700 AIKYVTV--DPTKKEIIMAMMMTACDLSAITKPWEVQSQVALMVANEFWEQGDLERTVLQ 757
Query: 368 MDISPMCDRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
PM DR+ + K QVGFID++ +++ ++ H + +L L+ NR ++S+
Sbjct: 758 QQPIPMMDRNKRDELPKLQVGFIDFVCTFVYKEFSRF-HKEITPMLSGLQNNRVEWKSL 815
>U20212-1|AAA92886.1| 858|Homo sapiens cone photoreceptor
cGMP-phosphodiesterase alpha' subunit protein.
Length = 858
Score = 55.2 bits (127), Expect = 1e-07
Identities = 46/179 (25%), Positives = 93/179 (51%), Gaps = 8/179 (4%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSL------LADLKTMVETKKV 190
LLQ++ +IF NL++ Q +T+ + +++TD++ + + D ++T++
Sbjct: 641 LLQDESLNIFQNLNKR-QFETVIHLFEVAIIATDLALYFKKRTMFQKIVDACEQMQTEEE 699
Query: 191 AGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRERE-HG 367
A V + + T + ++ ++ DLS TKP + + ++ EF++QGD ER
Sbjct: 700 AIKYVTV--DPTKKEIIMAMMMTACDLSAITKPWEVQSQVALMVANEFWEQGDLERTVLQ 757
Query: 368 MDISPMCDRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
PM DR+ + K QVGFID++ +++ ++ H + +L L+ NR ++S+
Sbjct: 758 QQPIPMMDRNKRDELPKLQVGFIDFVCTFVYKEFSRF-HKEITPMLSGLQNNRVEWKSL 815
>AL356214-7|CAH72330.1| 858|Homo sapiens phosphodiesterase 6C,
cGMP-specific, cone, alpha prime protein.
Length = 858
Score = 55.2 bits (127), Expect = 1e-07
Identities = 46/179 (25%), Positives = 93/179 (51%), Gaps = 8/179 (4%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSL------LADLKTMVETKKV 190
LLQ++ +IF NL++ Q +T+ + +++TD++ + + D ++T++
Sbjct: 641 LLQDESLNIFQNLNKR-QFETVIHLFEVAIIATDLALYFKKRTMFQKIVDACEQMQTEEE 699
Query: 191 AGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRERE-HG 367
A V + + T + ++ ++ DLS TKP + + ++ EF++QGD ER
Sbjct: 700 AIKYVTV--DPTKKEIIMAMMMTACDLSAITKPWEVQSQVALMVANEFWEQGDLERTVLQ 757
Query: 368 MDISPMCDRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
PM DR+ + K QVGFID++ +++ ++ H + +L L+ NR ++S+
Sbjct: 758 QQPIPMMDRNKRDELPKLQVGFIDFVCTFVYKEFSRF-HKEITPMLSGLQNNRVEWKSL 815
>AL157396-4|CAH73839.1| 858|Homo sapiens phosphodiesterase 6C,
cGMP-specific, cone, alpha prime protein.
Length = 858
Score = 55.2 bits (127), Expect = 1e-07
Identities = 46/179 (25%), Positives = 93/179 (51%), Gaps = 8/179 (4%)
Frame = +2
Query: 29 LLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMSKHMSL------LADLKTMVETKKV 190
LLQ++ +IF NL++ Q +T+ + +++TD++ + + D ++T++
Sbjct: 641 LLQDESLNIFQNLNKR-QFETVIHLFEVAIIATDLALYFKKRTMFQKIVDACEQMQTEEE 699
Query: 191 AGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRERE-HG 367
A V + + T + ++ ++ DLS TKP + + ++ EF++QGD ER
Sbjct: 700 AIKYVTV--DPTKKEIIMAMMMTACDLSAITKPWEVQSQVALMVANEFWEQGDLERTVLQ 757
Query: 368 MDISPMCDRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
PM DR+ + K QVGFID++ +++ ++ H + +L L+ NR ++S+
Sbjct: 758 QQPIPMMDRNKRDELPKLQVGFIDFVCTFVYKEFSRF-HKEITPMLSGLQNNRVEWKSL 815
>AC073834-2|AAX93113.1| 125|Homo sapiens unknown protein.
Length = 125
Score = 47.6 bits (108), Expect = 3e-05
Identities = 31/99 (31%), Positives = 54/99 (54%), Gaps = 2/99 (2%)
Frame = +2
Query: 251 LVHCADLSNPTKPLPLYKRWVALLMEEFFQQGDRER-EHGMDISPMCDRHNA-TIEKSQV 424
L+ DL TKP + ++ L+ EFF+QGDRER E + S + DR+ + + Q+
Sbjct: 3 LMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQL 62
Query: 425 GFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSM 541
+ID I PL++ V+ + +LD++ NR ++ +
Sbjct: 63 EWIDSICMPLYQALVK-VNVKLKPMLDSVATNRSKWEEL 100
>M94539-1|AAA58405.1| 116|Homo sapiens cyclic nucleotide
phosphodiesterase protein.
Length = 116
Score = 39.9 bits (89), Expect = 0.006
Identities = 19/38 (50%), Positives = 31/38 (81%)
Frame = +2
Query: 23 FKLLQNDGCDIFVNLHEEEQRQTLRKMVIDMVLSTDMS 136
F+L+Q+D +IF+NL ++E + LR +VI+MVL+TDM+
Sbjct: 80 FRLMQDDEMNIFINLTKDEFVE-LRALVIEMVLATDMA 116
>AB000520-1|BAA22514.1| 632|Homo sapiens APS protein.
Length = 632
Score = 29.5 bits (63), Expect = 8.0
Identities = 12/28 (42%), Positives = 17/28 (60%)
Frame = +1
Query: 112 HGPLDRYVETHESAGGSEDDGRNEESRG 195
H PL+ +++T ES GGS D N +G
Sbjct: 372 HVPLETFLQTLESPGGSGSDSNNTGEQG 399
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 84,534,254
Number of Sequences: 237096
Number of extensions: 1834593
Number of successful extensions: 8408
Number of sequences better than 10.0: 221
Number of HSP's better than 10.0 without gapping: 8079
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8199
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 5308067764
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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