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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= P5PG0227
         (428 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q6IDD9 Cluster: Sterile alpha and TIR motif-containing ...   207   9e-53
UniRef50_Q16F20 Cluster: Sarm1; n=3; Endopterygota|Rep: Sarm1 - ...   204   6e-52
UniRef50_UPI0000E4735D Cluster: PREDICTED: similar to ENSANGP000...   113   1e-24
UniRef50_Q6SZW1 Cluster: Sterile alpha and TIR motif-containing ...    99   3e-20
UniRef50_Q5BXY1 Cluster: SJCHGC09437 protein; n=1; Schistosoma j...    48   8e-05
UniRef50_Q86DA5 Cluster: Sterile alpha and TIR motif-containing ...    44   0.001
UniRef50_UPI0000361F1F Cluster: Angiopoietin-related protein 4 p...    35   0.62 
UniRef50_A6C787 Cluster: Serine/threonine kinase family protein;...    34   1.4  
UniRef50_Q6AP70 Cluster: 50S ribosomal protein L4; n=2; Desulfob...    33   3.3  
UniRef50_UPI0000DAE763 Cluster: hypothetical protein Rgryl_01001...    32   4.4  
UniRef50_A5B7U3 Cluster: Putative uncharacterized protein; n=1; ...    32   4.4  
UniRef50_UPI0000F2D088 Cluster: PREDICTED: similar to retinoblas...    32   5.8  
UniRef50_A4U2P0 Cluster: Large exoproteins involved in heme util...    32   5.8  
UniRef50_Q5UR18 Cluster: Putative t-SNARE coiled-coil homology d...    32   5.8  
UniRef50_Q4Q6D1 Cluster: Putative uncharacterized protein; n=3; ...    31   7.7  
UniRef50_A2EG43 Cluster: Putative uncharacterized protein; n=1; ...    31   7.7  
UniRef50_A7DSC1 Cluster: Type I site-specific deoxyribonuclease,...    31   7.7  

>UniRef50_Q6IDD9 Cluster: Sterile alpha and TIR motif-containing
           protein 1; n=6; Endopterygota|Rep: Sterile alpha and TIR
           motif-containing protein 1 - Drosophila melanogaster
           (Fruit fly)
          Length = 1360

 Score =  207 bits (505), Expect = 9e-53
 Identities = 96/121 (79%), Positives = 110/121 (90%)
 Frame = +1

Query: 13  TRGHELGYSLCNTLRTSGGLDILMANCLESNNPELQFSSAKLLEQCLTTENRAHVVENGL 192
           T GHELGYSLCN+LR SGGLD+LM NC++   P+LQFSSA+LLEQCLTTENR HVV+NGL
Sbjct: 389 THGHELGYSLCNSLRQSGGLDLLMKNCVK---PDLQFSSAQLLEQCLTTENRKHVVDNGL 445

Query: 193 EKVVNVACVCTKNANSVDHSRVGTGILEHLFKHSESTCDDVIKLGGLDAVLFECRKNDVE 372
           +KVVNVACVCTKN+N ++HSRVGTGILEHLFKHSE TC DVI+LGGLDAVLFECR +D+E
Sbjct: 446 DKVVNVACVCTKNSN-MEHSRVGTGILEHLFKHSEGTCSDVIRLGGLDAVLFECRTSDLE 504

Query: 373 T 375
           T
Sbjct: 505 T 505



 Score = 37.9 bits (84), Expect = 0.088
 Identities = 16/17 (94%), Positives = 17/17 (100%)
 Frame = +2

Query: 377 LRHCATALANLSLYGGA 427
           LRHCA+ALANLSLYGGA
Sbjct: 506 LRHCASALANLSLYGGA 522


>UniRef50_Q16F20 Cluster: Sarm1; n=3; Endopterygota|Rep: Sarm1 -
           Aedes aegypti (Yellowfever mosquito)
          Length = 1401

 Score =  204 bits (498), Expect = 6e-52
 Identities = 95/121 (78%), Positives = 109/121 (90%)
 Frame = +1

Query: 13  TRGHELGYSLCNTLRTSGGLDILMANCLESNNPELQFSSAKLLEQCLTTENRAHVVENGL 192
           T GHELG SLC+TLR +GGLD+LM NC+ +N+  +QFSSAKLLEQCLTTENR+HVV+NGL
Sbjct: 469 THGHELGASLCDTLRNTGGLDLLMKNCI-NNDSAVQFSSAKLLEQCLTTENRSHVVKNGL 527

Query: 193 EKVVNVACVCTKNANSVDHSRVGTGILEHLFKHSESTCDDVIKLGGLDAVLFECRKNDVE 372
           EKVVNVAC CTKN+ + DHSRVGTGIL+HLFKHSE TC +VI+LGGLDAVLFECRKNDVE
Sbjct: 528 EKVVNVACFCTKNSGT-DHSRVGTGILQHLFKHSEDTCSNVIRLGGLDAVLFECRKNDVE 586

Query: 373 T 375
           T
Sbjct: 587 T 587



 Score = 38.3 bits (85), Expect = 0.067
 Identities = 24/50 (48%), Positives = 28/50 (56%)
 Frame = +2

Query: 278 TCSSTARAPAMTSSN*EVWMRCCSNAEKTTWKPLRHCATALANLSLYGGA 427
           TCS+  R   + +    V   C  N  +T    LRHCA ALANLSLYGGA
Sbjct: 563 TCSNVIRLGGLDA----VLFECRKNDVET----LRHCAGALANLSLYGGA 604


>UniRef50_UPI0000E4735D Cluster: PREDICTED: similar to
           ENSANGP00000013511, partial; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to
           ENSANGP00000013511, partial - Strongylocentrotus
           purpuratus
          Length = 556

 Score =  113 bits (273), Expect = 1e-24
 Identities = 59/116 (50%), Positives = 76/116 (65%)
 Frame = +1

Query: 19  GHELGYSLCNTLRTSGGLDILMANCLESNNPELQFSSAKLLEQCLTTENRAHVVENGLEK 198
           G +L YS+ + LR  GGLDIL+ NC +S++  LQ +SA+LLEQ +T  NR  VV  GLE 
Sbjct: 206 GRDLAYSISDALRMEGGLDILLKNC-KSDDRALQLNSARLLEQIMTANNRDFVVRKGLES 264

Query: 199 VVNVACVCTKNANSVDHSRVGTGILEHLFKHSESTCDDVIKLGGLDAVLFECRKND 366
           VV +AC    +       ++G GILE+LFKHSE TC  VI  GGL AVL+ CR +D
Sbjct: 265 VVKLAC----SRKEPTLLQIGMGILENLFKHSEDTCTKVIDRGGLQAVLYSCRMSD 316



 Score = 32.3 bits (70), Expect = 4.4
 Identities = 12/17 (70%), Positives = 15/17 (88%)
 Frame = +2

Query: 377 LRHCATALANLSLYGGA 427
           LRHCA ALAN ++YGG+
Sbjct: 320 LRHCAAALANCAMYGGS 336


>UniRef50_Q6SZW1 Cluster: Sterile alpha and TIR motif-containing
           protein 1; n=23; Tetrapoda|Rep: Sterile alpha and TIR
           motif-containing protein 1 - Homo sapiens (Human)
          Length = 724

 Score = 99.1 bits (236), Expect = 3e-20
 Identities = 51/116 (43%), Positives = 71/116 (61%)
 Frame = +1

Query: 19  GHELGYSLCNTLRTSGGLDILMANCLESNNPELQFSSAKLLEQCLTTENRAHVVENGLEK 198
           G E+   LC+ +R  GGLD+L+   L++   E +  +A+LLEQ L  ENR  V   GL  
Sbjct: 109 GREVAQGLCDAIRLDGGLDLLL-RLLQAPELETRVQAARLLEQILVAENRDRVARIGLGV 167

Query: 199 VVNVACVCTKNANSVDHSRVGTGILEHLFKHSESTCDDVIKLGGLDAVLFECRKND 366
           ++N+A    K    V+ +R   GILEH+FKHSE TC  ++  GGLDAVL+ CR+ D
Sbjct: 168 ILNLA----KEREPVELARSVAGILEHMFKHSEETCQRLVAAGGLDAVLYWCRRTD 219


>UniRef50_Q5BXY1 Cluster: SJCHGC09437 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC09437 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 236

 Score = 48.0 bits (109), Expect = 8e-05
 Identities = 21/50 (42%), Positives = 32/50 (64%)
 Frame = +1

Query: 220 CTKNANSVDHSRVGTGILEHLFKHSESTCDDVIKLGGLDAVLFECRKNDV 369
           C +    VD  R   GILE L KH+E+ CD V++ GGL ++++ CR +D+
Sbjct: 2   CWEYREDVDIYREYLGILEPLLKHTETMCDAVVENGGLRSLIYACRSSDL 51


>UniRef50_Q86DA5 Cluster: Sterile alpha and TIR motif-containing
           protein tir-1; n=9; Caenorhabditis|Rep: Sterile alpha
           and TIR motif-containing protein tir-1 - Caenorhabditis
           elegans
          Length = 1000

 Score = 44.4 bits (100), Expect = 0.001
 Identities = 32/134 (23%), Positives = 62/134 (46%), Gaps = 3/134 (2%)
 Frame = +1

Query: 25  ELGYSLCNTLRTSGGLDILMANCLESNNP---ELQFSSAKLLEQCLTTENRAHVVENGLE 195
           +L  +LC+ LR     D L+   +  N     +++    K+LE+C ++ N  ++V     
Sbjct: 309 DLANALCDYLRDRDYFDKLIKMFISPNTAACDQVRMECGKVLEECTSSANLEYIVNKSYT 368

Query: 196 KVVNVACVCTKNANSVDHSRVGTGILEHLFKHSESTCDDVIKLGGLDAVLFECRKNDVET 375
           K + +  V  K   + D  R+   ++ +LFKHS +    +I+   +D ++    K   E 
Sbjct: 369 KKIMI--VAMKLNKTPDQQRLSLSLIGNLFKHSNAVSLSLIETDVIDHIILTF-KRAPEC 425

Query: 376 FETLRDGSSELISI 417
            + LR  +  L +I
Sbjct: 426 PDILRHAALALANI 439


>UniRef50_UPI0000361F1F Cluster: Angiopoietin-related protein 4
           precursor (Angiopoietin-like 4) (Hepatic
           fibrinogen/angiopoietin-related protein) (HFARP).; n=1;
           Takifugu rubripes|Rep: Angiopoietin-related protein 4
           precursor (Angiopoietin-like 4) (Hepatic
           fibrinogen/angiopoietin-related protein) (HFARP). -
           Takifugu rubripes
          Length = 412

 Score = 35.1 bits (77), Expect = 0.62
 Identities = 22/61 (36%), Positives = 30/61 (49%), Gaps = 2/61 (3%)
 Frame = +1

Query: 229 NANSVDHS--RVGTGILEHLFKHSESTCDDVIKLGGLDAVLFECRKNDVETFETLRDGSS 402
           + N V H   ++G G+ EH+ K    T D   KL  LDA + E  +   +  E LR GS 
Sbjct: 9   DVNVVSHGLLQLGQGLKEHVDKTKAQTRDVNAKLKSLDAAVEEVERRQRKQDEALRAGSK 68

Query: 403 E 405
           E
Sbjct: 69  E 69


>UniRef50_A6C787 Cluster: Serine/threonine kinase family protein;
           n=1; Planctomyces maris DSM 8797|Rep: Serine/threonine
           kinase family protein - Planctomyces maris DSM 8797
          Length = 1729

 Score = 33.9 bits (74), Expect = 1.4
 Identities = 17/55 (30%), Positives = 26/55 (47%)
 Frame = -1

Query: 407 SSLEPSRSVSKVSTSFFLHSNSTASRPPNLMTSSQVLSLCLNRCSKMPVPTREWS 243
           S + PS +  K +T FF  SNS  S+ P    +    +L  +  S + +P   WS
Sbjct: 503 SVINPSENGEKTATPFFAKSNSDGSKTPGTSGTKGKYALQFDGSSVVIIPNTNWS 557


>UniRef50_Q6AP70 Cluster: 50S ribosomal protein L4; n=2;
           Desulfobacterales|Rep: 50S ribosomal protein L4 -
           Desulfotalea psychrophila
          Length = 211

 Score = 32.7 bits (71), Expect = 3.3
 Identities = 15/38 (39%), Positives = 22/38 (57%)
 Frame = -3

Query: 309 IAGALAVLEQVLQNACTNSRVVHGIRILRTNTCDVYDL 196
           +A AL V++   +N   + R VHG RIL     +VYD+
Sbjct: 152 LANALIVMDDASENLSKSCRNVHGYRILPAEGLNVYDI 189


>UniRef50_UPI0000DAE763 Cluster: hypothetical protein
           Rgryl_01001156; n=1; Rickettsiella grylli|Rep:
           hypothetical protein Rgryl_01001156 - Rickettsiella
           grylli
          Length = 341

 Score = 32.3 bits (70), Expect = 4.4
 Identities = 21/74 (28%), Positives = 37/74 (50%)
 Frame = +1

Query: 193 EKVVNVACVCTKNANSVDHSRVGTGILEHLFKHSESTCDDVIKLGGLDAVLFECRKNDVE 372
           E V  + C+C      ++   + + +L+H+F   E+    VI L GL AV  E  KN ++
Sbjct: 41  EVVDRLECICKFRLKFIEGDILDSNLLDHIF--FENNISAVIHLAGLKAV-SESIKNPLK 97

Query: 373 TFETLRDGSSELIS 414
            +    +G+  LI+
Sbjct: 98  CYNNNVEGTLTLIN 111


>UniRef50_A5B7U3 Cluster: Putative uncharacterized protein; n=1;
           Vitis vinifera|Rep: Putative uncharacterized protein -
           Vitis vinifera (Grape)
          Length = 1162

 Score = 32.3 bits (70), Expect = 4.4
 Identities = 28/115 (24%), Positives = 47/115 (40%), Gaps = 4/115 (3%)
 Frame = +1

Query: 25  ELGYSLCNTLRTSG-GLDILMANCLESNNPELQFSSAKLLEQCLTTENRAHVVENGLEKV 201
           ++G S  N   + G   +++    L  NN  + FS    L   +    +   ++  +   
Sbjct: 353 DIGPSFQNVFVSPGLSANLISVGQLVDNNCNVSFSHGGCLGPKV---GQLFPLQFSIPSA 409

Query: 202 VNVACVCTKNANSVDHSRVG---TGILEHLFKHSESTCDDVIKLGGLDAVLFECR 357
           +++AC    N + V H R+G   + IL HLFKH      D     GL      C+
Sbjct: 410 LSLACSTVSNQSEVWHKRLGHPNSLILHHLFKHGFLGNKDQFSAHGLSIDCTSCK 464


>UniRef50_UPI0000F2D088 Cluster: PREDICTED: similar to retinoblastoma
            protein-binding zinc finger protein; n=1; Monodelphis
            domestica|Rep: PREDICTED: similar to retinoblastoma
            protein-binding zinc finger protein - Monodelphis
            domestica
          Length = 1822

 Score = 31.9 bits (69), Expect = 5.8
 Identities = 20/57 (35%), Positives = 30/57 (52%)
 Frame = -1

Query: 407  SSLEPSRSVSKVSTSFFLHSNSTASRPPNLMTSSQVLSLCLNRCSKMPVPTREWSTE 237
            SS   S S S  S+SF   S+S++  PP L   S V+S   N  + +P+  ++  TE
Sbjct: 1191 SSSSSSSSSSSSSSSFSSSSSSSSPSPPPLSVVSSVISSGDNLEAPLPISFKQEDTE 1247


>UniRef50_A4U2P0 Cluster: Large exoproteins involved in heme
           utilization or adhesion; n=1; Magnetospirillum
           gryphiswaldense|Rep: Large exoproteins involved in heme
           utilization or adhesion - Magnetospirillum
           gryphiswaldense
          Length = 201

 Score = 31.9 bits (69), Expect = 5.8
 Identities = 13/31 (41%), Positives = 16/31 (51%)
 Frame = +3

Query: 216 CLYEECEFRGPLSSWYRHFGAPVQAQREHLR 308
           C   E +FRG  S+W   FG  + A   HLR
Sbjct: 52  CQGTEVDFRGKWSTWVNRFGTTMNANATHLR 82


>UniRef50_Q5UR18 Cluster: Putative t-SNARE coiled-coil homology
           domain-containing protein L657; n=1; Acanthamoeba
           polyphaga mimivirus|Rep: Putative t-SNARE coiled-coil
           homology domain-containing protein L657 - Mimivirus
          Length = 204

 Score = 31.9 bits (69), Expect = 5.8
 Identities = 17/50 (34%), Positives = 27/50 (54%), Gaps = 1/50 (2%)
 Frame = +1

Query: 103 NNPELQFSSAK-LLEQCLTTENRAHVVENGLEKVVNVACVCTKNANSVDH 249
           NN E+Q + A   L+     +N  H  E+ +EK+ N+ CV  K AN + +
Sbjct: 122 NNSEIQDNFANNFLDN--PPDNSRHFSEDNIEKLHNIVCVLEKQANDISN 169


>UniRef50_Q4Q6D1 Cluster: Putative uncharacterized protein; n=3;
           Leishmania|Rep: Putative uncharacterized protein -
           Leishmania major
          Length = 2563

 Score = 31.5 bits (68), Expect = 7.7
 Identities = 19/66 (28%), Positives = 30/66 (45%), Gaps = 1/66 (1%)
 Frame = -1

Query: 413 EISSLEPSRSVSKVSTSFFLHSNSTASRPPNLMTSSQVLSLCLNRCSKM-PVPTREWSTE 237
           + S L  +RS+S++  +    + S    PP L T+   L+  L RC+   P        +
Sbjct: 455 DTSELPATRSLSRLPLAKLTATESVRPSPPPLATAPPALASHLKRCTPSGPSAPASTKPQ 514

Query: 236 FAFFVQ 219
           F FF Q
Sbjct: 515 FRFFAQ 520


>UniRef50_A2EG43 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 499

 Score = 31.5 bits (68), Expect = 7.7
 Identities = 15/53 (28%), Positives = 29/53 (54%)
 Frame = +1

Query: 43  CNTLRTSGGLDILMANCLESNNPELQFSSAKLLEQCLTTENRAHVVENGLEKV 201
           C+    +G L+IL  N + S +PE+ + + K+L      EN+  + E+  +K+
Sbjct: 101 CSQFIQNGLLEILCENIINSTSPEMSYYNLKILHHIAGHENK-EIFESLFQKI 152


>UniRef50_A7DSC1 Cluster: Type I site-specific deoxyribonuclease,
           HsdR family; n=1; Candidatus Nitrosopumilus maritimus
           SCM1|Rep: Type I site-specific deoxyribonuclease, HsdR
           family - Candidatus Nitrosopumilus maritimus SCM1
          Length = 1006

 Score = 31.5 bits (68), Expect = 7.7
 Identities = 14/33 (42%), Positives = 19/33 (57%)
 Frame = +1

Query: 262 TGILEHLFKHSESTCDDVIKLGGLDAVLFECRK 360
           T   +HL   +E  CD VI + G+  VL EC+K
Sbjct: 147 TNQFKHLGNRTEIECDIVIFVNGIPLVLIECKK 179


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.317    0.133    0.395 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 457,267,951
Number of Sequences: 1657284
Number of extensions: 8846221
Number of successful extensions: 26889
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 26096
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 26869
length of database: 575,637,011
effective HSP length: 93
effective length of database: 421,509,599
effective search space used: 20653970351
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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