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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= P5PG0179
         (694 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_P07954 Cluster: Fumarate hydratase, mitochondrial precu...   256   5e-67
UniRef50_Q0DS22 Cluster: Os03g0337900 protein; n=4; Eukaryota|Re...   229   5e-59
UniRef50_Q2U6Q8 Cluster: Fumarase; n=9; cellular organisms|Rep: ...   225   1e-57
UniRef50_UPI0000D99F3D Cluster: PREDICTED: fumarate hydratase is...   214   2e-54
UniRef50_Q29NH7 Cluster: GA16542-PA; n=1; Drosophila pseudoobscu...   203   4e-51
UniRef50_Q83ML8 Cluster: Fumarate hydratase class II; n=75; cell...   182   6e-45
UniRef50_Q89XM2 Cluster: Fumarate hydratase class II 2; n=9; Bac...   178   1e-43
UniRef50_Q92GW0 Cluster: Fumarate hydratase class II; n=35; cell...   176   4e-43
UniRef50_Q11C85 Cluster: Fumarate lyase; n=2; Proteobacteria|Rep...   171   1e-41
UniRef50_Q9PD25 Cluster: Fumarate hydratase class II; n=78; Prot...   146   3e-34
UniRef50_Q7UNE6 Cluster: Fumarate hydratase FumC; n=2; Planctomy...   144   2e-33
UniRef50_Q5H160 Cluster: Fumarate hydratase; n=13; Gammaproteoba...   143   3e-33
UniRef50_A5UYJ9 Cluster: Fumarate lyase; n=22; Bacteria|Rep: Fum...   141   2e-32
UniRef50_Q9RFN4 Cluster: L-aspartase; n=26; Bacteria|Rep: L-aspa...   140   2e-32
UniRef50_Q82ID7 Cluster: Fumarate hydratase class II; n=20; cell...   140   4e-32
UniRef50_Q1IN60 Cluster: Fumarate lyase; n=2; Bacteria|Rep: Fuma...   136   4e-31
UniRef50_Q8G7D1 Cluster: Aspartate ammonia-lyase; n=2; Bifidobac...   135   1e-30
UniRef50_Q978Q5 Cluster: Fumarase; n=4; Thermoplasmatales|Rep: F...   133   3e-30
UniRef50_Q938V7 Cluster: Aspartate ammonium lyase; n=1; Bradyrhi...   132   1e-29
UniRef50_Q8FQP8 Cluster: Fumarate hydratase class II; n=35; Bact...   131   2e-29
UniRef50_A6DXB5 Cluster: Fumarate hydratase; n=1; Roseovarius sp...   130   4e-29
UniRef50_P56149 Cluster: Aspartate ammonia-lyase; n=86; cellular...   127   3e-28
UniRef50_Q010D6 Cluster: Fumarase; n=2; Eukaryota|Rep: Fumarase ...   125   1e-27
UniRef50_A0RW57 Cluster: Fumarate hydratase/fumarase; n=3; Crena...   124   2e-27
UniRef50_Q9KNN3 Cluster: Aspartate ammonia-lyase; n=27; Bacteria...   122   6e-27
UniRef50_P26899 Cluster: Aspartate ammonia-lyase; n=44; Bacteria...   122   1e-26
UniRef50_Q9WYS5 Cluster: Aspartate ammonia-lyase; n=4; Thermotog...   120   3e-26
UniRef50_Q30VF1 Cluster: Aspartate ammonia-lyase, putative; n=1;...   120   4e-26
UniRef50_A1B109 Cluster: Aspartate ammonia-lyase; n=1; Paracoccu...   119   8e-26
UniRef50_Q00SM0 Cluster: Aspartate ammonia-lyase; n=4; cellular ...   118   1e-25
UniRef50_P07346 Cluster: Aspartate ammonia-lyase; n=22; Bacteria...   118   1e-25
UniRef50_P39461 Cluster: Fumarate hydratase class II; n=10; Ther...   115   1e-24
UniRef50_Q88TT7 Cluster: Aspartate ammonia-lyase; n=2; Lactobaci...   112   7e-24
UniRef50_Q74IW1 Cluster: Fumarate hydratase; n=4; Bacteria|Rep: ...   110   3e-23
UniRef50_Q59200 Cluster: Aspartate ammonia-lyase; n=117; Bacteri...   110   4e-23
UniRef50_A3Y7G3 Cluster: Hypothetical aspartate ammonia-lyase; n...   101   2e-20
UniRef50_UPI0000510540 Cluster: COG1027: Aspartate ammonia-lyase...    94   3e-18
UniRef50_A3SJ56 Cluster: Aspartate ammonia-lyase; n=1; Roseovari...    90   4e-17
UniRef50_A4NYC4 Cluster: Fumarate hydratase; n=1; Haemophilus in...    83   8e-15
UniRef50_UPI0000499E1B Cluster: aspartase-related; n=1; Entamoeb...    78   2e-13
UniRef50_A0VSJ0 Cluster: Putative uncharacterized protein; n=3; ...    77   3e-13
UniRef50_Q1LB63 Cluster: Fumarate hydratase, class II; n=1; Rals...    75   1e-12
UniRef50_Q12ZL4 Cluster: Fumarate hydratase class II; n=1; Metha...    71   3e-11
UniRef50_Q4J197 Cluster: Putative uncharacterized protein; n=1; ...    59   1e-07
UniRef50_A4NYC9 Cluster: Fumarate hydratase; n=1; Haemophilus in...    54   3e-06
UniRef50_A5NX44 Cluster: Putative uncharacterized protein; n=1; ...    53   6e-06
UniRef50_A0U0K7 Cluster: Putative uncharacterized protein; n=1; ...    53   8e-06
UniRef50_A7DHF3 Cluster: Putative uncharacterized protein precur...    44   0.005
UniRef50_UPI0000499F8A Cluster: aspartate ammonia-lyase; n=1; En...    42   0.019
UniRef50_A5NPW1 Cluster: Putative uncharacterized protein; n=1; ...    40   0.044
UniRef50_A1G5B1 Cluster: Putative uncharacterized protein; n=1; ...    40   0.044
UniRef50_A0VGM0 Cluster: Putative uncharacterized protein; n=3; ...    39   0.10 
UniRef50_A3HI19 Cluster: Putative uncharacterized protein; n=2; ...    38   0.23 
UniRef50_A0TG73 Cluster: RNA binding protein, putative; n=2; Bur...    38   0.23 
UniRef50_UPI00015B53F3 Cluster: PREDICTED: hypothetical protein;...    36   0.94 
UniRef50_A7D1M8 Cluster: Putative uncharacterized protein; n=1; ...    36   1.2  
UniRef50_Q0CRV8 Cluster: Predicted protein; n=1; Aspergillus ter...    33   5.0  
UniRef50_Q6UWB1 Cluster: Interleukin-27 receptor subunit alpha p...    33   6.6  
UniRef50_Q39PM2 Cluster: Putative uncharacterized protein; n=1; ...    33   8.8  
UniRef50_Q2SCH6 Cluster: Putative uncharacterized protein; n=2; ...    33   8.8  
UniRef50_Q22441 Cluster: Putative uncharacterized protein; n=2; ...    33   8.8  

>UniRef50_P07954 Cluster: Fumarate hydratase, mitochondrial
           precursor; n=500; cellular organisms|Rep: Fumarate
           hydratase, mitochondrial precursor - Homo sapiens
           (Human)
          Length = 510

 Score =  256 bits (626), Expect = 5e-67
 Identities = 122/170 (71%), Positives = 142/170 (83%)
 Frame = +2

Query: 185 RKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVAFGILKKAAAKVNIEY 364
           R E DTFGEL VP+DK YGAQTVRS MNF IGG+ ERMP PVI AFGILK+AAA+VN +Y
Sbjct: 51  RIEYDTFGELKVPNDKYYGAQTVRSTMNFKIGGVTERMPTPVIKAFGILKRAAAEVNQDY 110

Query: 365 GLEKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIANRAIQILGGK 544
           GL+ KIA+AIM+A D+V  GKL    HFPLV+WQTGSGTQ+NMN NEVI+NRAI++LGG+
Sbjct: 111 GLDPKIANAIMKAADEVAEGKL--NDHFPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGE 168

Query: 545 LGSKDPVHPNDHVNKSQSSNDTYPTXMHIAVAMELRDRLMPGLVXLRDTL 694
           LGSK PVHPNDHVNKSQSSNDT+PT MHIA A+E+ + L+PGL  L D L
Sbjct: 169 LGSKIPVHPNDHVNKSQSSNDTFPTAMHIAAAIEVHEVLLPGLQKLHDAL 218


>UniRef50_Q0DS22 Cluster: Os03g0337900 protein; n=4; Eukaryota|Rep:
           Os03g0337900 protein - Oryza sativa subsp. japonica
           (Rice)
          Length = 469

 Score =  229 bits (560), Expect = 5e-59
 Identities = 112/170 (65%), Positives = 131/170 (77%)
 Frame = +2

Query: 185 RKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVAFGILKKAAAKVNIEY 364
           R+E+DTFG + VP+DKL+GAQT RS+ NF IGG  ERMP P+I AFG+LKK AAKVN+EY
Sbjct: 43  REERDTFGPIRVPNDKLWGAQTQRSLQNFDIGGERERMPVPIIRAFGVLKKCAAKVNMEY 102

Query: 365 GLEKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIANRAIQILGGK 544
           GL+  I  AIMQA  +V  G+L  + HFPLVIWQTGSGTQSNMN NEVIANRA +ILG K
Sbjct: 103 GLDPTIGKAIMQAAQEVAEGQL--DDHFPLVIWQTGSGTQSNMNANEVIANRAAEILGHK 160

Query: 545 LGSKDPVHPNDHVNKSQSSNDTYPTXMHIAVAMELRDRLMPGLVXLRDTL 694
            G K  VHPNDHVN+SQSSNDT+PT MHIA A E+  R +P L  L  +L
Sbjct: 161 RGEKF-VHPNDHVNRSQSSNDTFPTVMHIAAATEINSRFVPSLQQLHKSL 209


>UniRef50_Q2U6Q8 Cluster: Fumarase; n=9; cellular organisms|Rep:
           Fumarase - Aspergillus oryzae
          Length = 549

 Score =  225 bits (549), Expect = 1e-57
 Identities = 112/185 (60%), Positives = 137/185 (74%), Gaps = 3/185 (1%)
 Frame = +2

Query: 149 NKRNISTTSVTA---RKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVA 319
           +KR   TT+  A   R E D FGE++VP DK +GAQT RS+ NF I   ++RMP  V+ A
Sbjct: 72  SKRTFGTTARMASETRVETDAFGEIEVPADKYWGAQTQRSLGNFDINQPQDRMPEGVVKA 131

Query: 320 FGILKKAAAKVNIEYGLEKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNT 499
           FGILK AAA VN+++GL+ KI +AI +A  +V  GKL    HFPLV+WQTGSGTQSNMN+
Sbjct: 132 FGILKGAAATVNMKFGLDPKIGEAIQKAAAEVAEGKLM--DHFPLVVWQTGSGTQSNMNS 189

Query: 500 NEVIANRAIQILGGKLGSKDPVHPNDHVNKSQSSNDTYPTXMHIAVAMELRDRLMPGLVX 679
           NEVI+NRAI+ILGGK+GSK PVHPNDHVN S SSND++PT MHIA  +EL   L+P L  
Sbjct: 190 NEVISNRAIEILGGKMGSKKPVHPNDHVNMSASSNDSFPTAMHIAAVLELEGTLLPSLKS 249

Query: 680 LRDTL 694
           LRD L
Sbjct: 250 LRDAL 254


>UniRef50_UPI0000D99F3D Cluster: PREDICTED: fumarate hydratase
           isoform 1; n=2; Eutheria|Rep: PREDICTED: fumarate
           hydratase isoform 1 - Macaca mulatta
          Length = 449

 Score =  214 bits (522), Expect = 2e-54
 Identities = 102/137 (74%), Positives = 117/137 (85%)
 Frame = +2

Query: 185 RKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVAFGILKKAAAKVNIEY 364
           R E DTFGEL VP+DK YGAQTVRS MNF IGG+ ERMP PVI AFGILK+AAA+VN +Y
Sbjct: 51  RIEYDTFGELKVPNDKYYGAQTVRSTMNFKIGGVTERMPTPVIKAFGILKRAAAEVNQDY 110

Query: 365 GLEKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIANRAIQILGGK 544
           GL+ KIA+AIM+A D+V  GKL    HFPLV+WQTGSGTQ+NMN NEVI+NRAI++LGG+
Sbjct: 111 GLDPKIANAIMKAADEVAEGKL--NDHFPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGE 168

Query: 545 LGSKDPVHPNDHVNKSQ 595
           LGSK PVHPNDHVNKSQ
Sbjct: 169 LGSKIPVHPNDHVNKSQ 185


>UniRef50_Q29NH7 Cluster: GA16542-PA; n=1; Drosophila
           pseudoobscura|Rep: GA16542-PA - Drosophila pseudoobscura
           (Fruit fly)
          Length = 501

 Score =  203 bits (495), Expect = 4e-51
 Identities = 101/188 (53%), Positives = 130/188 (69%), Gaps = 18/188 (9%)
 Frame = +2

Query: 185 RKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPY------------------PV 310
           R E D+ G + VP D+LYG QT+RS++ FPIGG+ ERMP                   P+
Sbjct: 24  RVEYDSMGAVHVPLDRLYGPQTMRSLLKFPIGGVNERMPVGQMHFCEVFIVNRFTLQRPI 83

Query: 311 IVAFGILKKAAAKVNIEYGLEKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSN 490
           I+A  I+KKA A+ N   GLE+++ DAI +ACDD+ISGKLY E HFPLVIWQ GSG  +N
Sbjct: 84  IIALAIVKKAVAETNKMSGLEERLCDAISKACDDIISGKLYDEDHFPLVIWQAGSGRHTN 143

Query: 491 MNTNEVIANRAIQILGGKLGSKDPVHPNDHVNKSQSSNDTYPTXMHIAVAMELRDRLMPG 670
           MN NEVI NRAI+ILGG+ G+K PV P+ HVN SQSSND++   ++IAVAM+LRD+L P 
Sbjct: 144 MNVNEVICNRAIEILGGQKGTKTPVDPDQHVNLSQSSNDSFSAAINIAVAMQLRDKLYPA 203

Query: 671 LVXLRDTL 694
           L  + + L
Sbjct: 204 LTLIIEVL 211


>UniRef50_Q83ML8 Cluster: Fumarate hydratase class II; n=75;
           cellular organisms|Rep: Fumarate hydratase class II -
           Shigella flexneri
          Length = 467

 Score =  182 bits (444), Expect = 6e-45
 Identities = 95/173 (54%), Positives = 121/173 (69%), Gaps = 1/173 (0%)
 Frame = +2

Query: 179 TARKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVAFGILKKAAAKVNI 358
           T R EKD+ G +DVP DKL+GAQT RS+ +F I    E+MP  +I A  + K+AAAKVN 
Sbjct: 3   TVRSEKDSMGAIDVPADKLWGAQTQRSLEHFRIS--TEKMPTSLIHALALTKRAAAKVNE 60

Query: 359 EYGL-EKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIANRAIQIL 535
           +  L  ++ A AI QA D+V++G+   +  FPL IWQTGSGTQSNMN NEV+ANRA ++L
Sbjct: 61  DLDLLSEEKASAIRQAADEVLAGQ--HDDEFPLAIWQTGSGTQSNMNMNEVLANRASELL 118

Query: 536 GGKLGSKDPVHPNDHVNKSQSSNDTYPTXMHIAVAMELRDRLMPGLVXLRDTL 694
           GG  G +  VHPND VNKSQSSND +PT MH+A  + LR +L+P L  L  TL
Sbjct: 119 GGVRGMERKVHPNDDVNKSQSSNDVFPTAMHVAALLALRKQLIPQLKTLTQTL 171


>UniRef50_Q89XM2 Cluster: Fumarate hydratase class II 2; n=9;
           Bacteria|Rep: Fumarate hydratase class II 2 -
           Bradyrhizobium japonicum
          Length = 478

 Score =  178 bits (433), Expect = 1e-43
 Identities = 90/171 (52%), Positives = 118/171 (69%), Gaps = 1/171 (0%)
 Frame = +2

Query: 185 RKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVAFGILKKAAAKVNIEY 364
           RKE D+ GE++VP DKL+GAQT RS+ +F IG   + MP  +I ++ ILKKAAA  N   
Sbjct: 5   RKETDSLGEVNVPADKLWGAQTQRSLEHFSIG--RDLMPREMIQSYAILKKAAANANYAG 62

Query: 365 G-LEKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIANRAIQILGG 541
           G L+ KI   I+  CD++++G+      FPL +W TGSGTQ NMN NEVI+NR  Q+ G 
Sbjct: 63  GRLDGKIHKLIVHTCDEILAGQ--HHDMFPLHVWMTGSGTQFNMNVNEVISNRCCQLAGT 120

Query: 542 KLGSKDPVHPNDHVNKSQSSNDTYPTXMHIAVAMELRDRLMPGLVXLRDTL 694
            LGSK PVHPNDHVN SQSSND++P+ M+IA AM +  RL+P +  L D +
Sbjct: 121 ALGSKLPVHPNDHVNMSQSSNDSFPSAMYIAAAMNVTQRLVPAVEALHDAI 171


>UniRef50_Q92GW0 Cluster: Fumarate hydratase class II; n=35;
           cellular organisms|Rep: Fumarate hydratase class II -
           Rickettsia conorii
          Length = 463

 Score =  176 bits (429), Expect = 4e-43
 Identities = 90/164 (54%), Positives = 118/164 (71%), Gaps = 1/164 (0%)
 Frame = +2

Query: 185 RKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVAFGILKKAAAKVNIEY 364
           R E D+FGE+ + +   +GAQT RS+ NF IG  +++MP  +I A  ILKK AA+VN E+
Sbjct: 5   RTESDSFGEIQIEEKFYWGAQTQRSLENFKIG--KQKMPEILIRALAILKKCAAQVNHEF 62

Query: 365 G-LEKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIANRAIQILGG 541
           G LE KIA +I +A D ++ G+   E +FPLV+WQTGSGTQ+NMN NEVIA+ A + L G
Sbjct: 63  GDLEAKIAISIDKATDRILEGEF--EDNFPLVVWQTGSGTQTNMNMNEVIASIANEELTG 120

Query: 542 KLGSKDPVHPNDHVNKSQSSNDTYPTXMHIAVAMELRDRLMPGL 673
           K G K PVHPNDHVNK QSSND++PT MHIA  +  + +L+P L
Sbjct: 121 KKGGKSPVHPNDHVNKGQSSNDSFPTAMHIATVLATKQQLIPAL 164


>UniRef50_Q11C85 Cluster: Fumarate lyase; n=2; Proteobacteria|Rep:
           Fumarate lyase - Mesorhizobium sp. (strain BNC1)
          Length = 470

 Score =  171 bits (416), Expect = 1e-41
 Identities = 81/167 (48%), Positives = 116/167 (69%), Gaps = 1/167 (0%)
 Frame = +2

Query: 176 VTARKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVAFGILKKAAAKVN 355
           +T R E D  G +++P D+ +GAQT R++  FP  G   R+P   + AFG+ K AAA+ N
Sbjct: 1   MTIRSESDANGPIEIPADRYWGAQTARALRLFPQEG--PRLPVSFLRAFGLQKAAAARAN 58

Query: 356 IEYG-LEKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIANRAIQI 532
           +  G L+++  + I+ A  ++  G+   + HFPL IWQTGSGTQ+NMN NEV+ANRA ++
Sbjct: 59  MALGVLDRERGERILAAAVELRDGRF--DDHFPLSIWQTGSGTQTNMNANEVLANRANEL 116

Query: 533 LGGKLGSKDPVHPNDHVNKSQSSNDTYPTXMHIAVAMELRDRLMPGL 673
            G  LG++DP+HPNDHVN  QSSNDT+PT MH+A  +EL+D ++P L
Sbjct: 117 SGQPLGTRDPIHPNDHVNLGQSSNDTFPTVMHVAAVLELQDGVLPAL 163


>UniRef50_Q9PD25 Cluster: Fumarate hydratase class II; n=78;
           Proteobacteria|Rep: Fumarate hydratase class II -
           Xylella fastidiosa
          Length = 473

 Score =  146 bits (355), Expect = 3e-34
 Identities = 83/168 (49%), Positives = 106/168 (63%), Gaps = 1/168 (0%)
 Frame = +2

Query: 185 RKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVAFGILKKAAAKVNIEY 364
           R E D+ G+L VP D L+GAQT R++ NFPI G    MP   I A G +K AAAKVN E 
Sbjct: 12  RIEHDSMGDLRVPIDALWGAQTQRAIENFPISG--RSMPQGFIHALGFIKAAAAKVNAEL 69

Query: 365 GL-EKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIANRAIQILGG 541
           GL  K +A  I  A  DV +G+   +  FP+ I+QTGSGT SNMN NEVIA  A++    
Sbjct: 70  GLLPKPMAKEIEAAALDVAAGRY--DADFPVDIYQTGSGTSSNMNANEVIATLAMR---- 123

Query: 542 KLGSKDPVHPNDHVNKSQSSNDTYPTXMHIAVAMELRDRLMPGLVXLR 685
              +K+P+HPNDHVN  QSSND  PT + I+  + ++ RL+P L  LR
Sbjct: 124 --ATKEPIHPNDHVNLGQSSNDVVPTAIRISATLAVQGRLLPALKHLR 169


>UniRef50_Q7UNE6 Cluster: Fumarate hydratase FumC; n=2;
           Planctomycetaceae|Rep: Fumarate hydratase FumC -
           Rhodopirellula baltica
          Length = 543

 Score =  144 bits (348), Expect = 2e-33
 Identities = 75/180 (41%), Positives = 114/180 (63%), Gaps = 10/180 (5%)
 Frame = +2

Query: 185 RKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVAFGILKKAAAKVNIEY 364
           R E+D+ GE+ VP +  YGAQT R+V NFP+ G +  +P  +I A G +K A    N + 
Sbjct: 74  RTERDSMGEVRVPQNAYYGAQTQRAVENFPVSGWQ--LPPSMIAAMGRVKLACGIANRDL 131

Query: 365 G---------LEKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIAN 517
           G         L     ++++ A  +V  G+L  +  FP+ ++QTGSGT SNMN NEV++N
Sbjct: 132 GKLTGSGKNPLSDGQVESMLSAAKEVAEGQLADQ--FPVDVFQTGSGTSSNMNINEVLSN 189

Query: 518 RAIQILGG-KLGSKDPVHPNDHVNKSQSSNDTYPTXMHIAVAMELRDRLMPGLVXLRDTL 694
           RAI+I GG ++  +  +HPNDH+N  QS+NDT+PT +H+A A E+ +RL+P L  + ++L
Sbjct: 190 RAIEIDGGDRMAEEKSIHPNDHINMGQSTNDTFPTAIHVAAAYEIENRLLPALRRMHESL 249


>UniRef50_Q5H160 Cluster: Fumarate hydratase; n=13;
           Gammaproteobacteria|Rep: Fumarate hydratase -
           Xanthomonas oryzae pv. oryzae
          Length = 472

 Score =  143 bits (347), Expect = 3e-33
 Identities = 80/171 (46%), Positives = 100/171 (58%), Gaps = 1/171 (0%)
 Frame = +2

Query: 185 RKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVAFGILKKAAAKVNIEY 364
           R E D  GEL VP D L+GAQT R+V NFP+ G  + MP   I A G++K AAA VN E 
Sbjct: 11  RTEHDCMGELQVPADALWGAQTQRAVQNFPVSG--QPMPRGFIRALGLIKAAAAGVNAEL 68

Query: 365 GL-EKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIANRAIQILGG 541
           GL  K I   +  A   V  G    +  FP+ ++QTGSGT SNMN NEVIA  A +    
Sbjct: 69  GLLPKSICKTVQAAALQVAEGSF--DAQFPIDVYQTGSGTSSNMNANEVIATLATR---- 122

Query: 542 KLGSKDPVHPNDHVNKSQSSNDTYPTXMHIAVAMELRDRLMPGLVXLRDTL 694
               KD VHPNDHVN  QSSND  PT + ++  + +++ L P L  LR T+
Sbjct: 123 --AGKDAVHPNDHVNLGQSSNDVVPTAIRVSALLAVQEHLQPALKHLRKTI 171


>UniRef50_A5UYJ9 Cluster: Fumarate lyase; n=22; Bacteria|Rep:
           Fumarate lyase - Roseiflexus sp. RS-1
          Length = 484

 Score =  141 bits (341), Expect = 2e-32
 Identities = 87/184 (47%), Positives = 113/184 (61%), Gaps = 14/184 (7%)
 Frame = +2

Query: 185 RKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIV-AFGILKKAAAKVNIE 361
           R EKD+ GE+ VP + LYGAQT R+VMNFP+ G+    PYP  V A  ++K+AAA+VN +
Sbjct: 6   RIEKDSLGEVRVPANALYGAQTQRAVMNFPVSGMR---PYPAFVWAQAMIKRAAAEVNRD 62

Query: 362 YGL------------EKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNE 505
            GL             ++IADAI+QA D+V+ G+      F +  +Q G+GT  NMN NE
Sbjct: 63  LGLFNDVTIGDRTISGRQIADAIIQAADEVLDGQ--HADQFVVDPFQAGAGTSHNMNLNE 120

Query: 506 VIANRAIQILGGKLGS-KDPVHPNDHVNKSQSSNDTYPTXMHIAVAMELRDRLMPGLVXL 682
           VIANRA QILG  L   K PV PNDHVN +QS+NDT PT + +     L D L+  +  L
Sbjct: 121 VIANRANQILGFALDDPKKPVSPNDHVNMAQSTNDTIPTAIRLGCLWRL-DELLAAIDRL 179

Query: 683 RDTL 694
            D L
Sbjct: 180 ADAL 183


>UniRef50_Q9RFN4 Cluster: L-aspartase; n=26; Bacteria|Rep:
           L-aspartase - Rhizobium etli
          Length = 475

 Score =  140 bits (340), Expect = 2e-32
 Identities = 78/176 (44%), Positives = 111/176 (63%), Gaps = 3/176 (1%)
 Frame = +2

Query: 167 TTS--VTARKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVAFGILKKA 340
           TTS   T R E D  G+ DVP    YG  TVR+V NFPI G   +    +I +   +K+A
Sbjct: 2   TTSDMTTIRVEHDLIGDRDVPASAYYGVHTVRAVENFPITGQTLKESADLIASLAAIKQA 61

Query: 341 AAKVNIEYGL-EKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIAN 517
           AA+VN+  GL +++ ADAI+ AC ++  G L+ +  F + + Q G+GT +NMN NEVIAN
Sbjct: 62  AAEVNVSLGLLDQQRADAIVAACIEIRDGALHDQ--FVVDLIQGGAGTSTNMNANEVIAN 119

Query: 518 RAIQILGGKLGSKDPVHPNDHVNKSQSSNDTYPTXMHIAVAMELRDRLMPGLVXLR 685
           RA++ILG + G    +HPN+HVN SQS+ND YPT + +A  + +  RL+  +  LR
Sbjct: 120 RALEILGHRRGEYQHLHPNEHVNLSQSTNDVYPTALKLAAWIGVH-RLVDAMAILR 174


>UniRef50_Q82ID7 Cluster: Fumarate hydratase class II; n=20;
           cellular organisms|Rep: Fumarate hydratase class II -
           Streptomyces avermitilis
          Length = 467

 Score =  140 bits (338), Expect = 4e-32
 Identities = 83/171 (48%), Positives = 107/171 (62%), Gaps = 1/171 (0%)
 Frame = +2

Query: 185 RKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVAFGILKKAAAKVNIEY 364
           R E D+ GE+ VP D  + AQT R+V NFPI G  +R+    I A   +K AAAKVN E 
Sbjct: 11  RVEHDSMGEVRVPADAKWRAQTQRAVENFPISG--QRLERAHIEALARIKGAAAKVNAEL 68

Query: 365 G-LEKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIANRAIQILGG 541
           G L+K +A+AI +A  +V  G+   + HFP+ ++QTGSGT SNMN NEVIA  A + LG 
Sbjct: 69  GVLDKDVAEAIQEAAAEVAEGRW--DEHFPVDVFQTGSGTSSNMNANEVIATLATERLG- 125

Query: 542 KLGSKDPVHPNDHVNKSQSSNDTYPTXMHIAVAMELRDRLMPGLVXLRDTL 694
               +D VHPNDHVN SQSSND +P+ +HIA    +   L+P L  L   L
Sbjct: 126 ----RD-VHPNDHVNASQSSNDVFPSSIHIAATAAVTRDLVPALEHLAAAL 171


>UniRef50_Q1IN60 Cluster: Fumarate lyase; n=2; Bacteria|Rep:
           Fumarate lyase - Acidobacteria bacterium (strain
           Ellin345)
          Length = 476

 Score =  136 bits (330), Expect = 4e-31
 Identities = 72/167 (43%), Positives = 108/167 (64%), Gaps = 1/167 (0%)
 Frame = +2

Query: 176 VTARKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVAFGILKKAAAKVN 355
           +  R+EKD+ G  DVP D  YG QT R+V N+PI G+  R    +I A  ++K+AAA+ N
Sbjct: 1   MATRQEKDSLGYKDVPADAYYGIQTARAVENYPISGM--RAHATLIRAIAMVKQAAAEAN 58

Query: 356 IEYGL-EKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIANRAIQI 532
           +E  L + ++A+A++ A  ++  G+   +  F + ++Q G+G   ++N NEVIANRA ++
Sbjct: 59  LELDLIDARVAEALILAAKEMQEGRW--DDQFVVDVFQAGAGVSFHINANEVIANRAEEL 116

Query: 533 LGGKLGSKDPVHPNDHVNKSQSSNDTYPTXMHIAVAMELRDRLMPGL 673
            GGKLG    VHPNDHVN  QS+ND +PT M +A  +EL ++L P L
Sbjct: 117 TGGKLGEYKIVHPNDHVNYGQSTNDVFPTAMRLATLLEL-EKLYPVL 162


>UniRef50_Q8G7D1 Cluster: Aspartate ammonia-lyase; n=2;
           Bifidobacterium longum|Rep: Aspartate ammonia-lyase -
           Bifidobacterium longum
          Length = 490

 Score =  135 bits (326), Expect = 1e-30
 Identities = 71/161 (44%), Positives = 102/161 (63%), Gaps = 1/161 (0%)
 Frame = +2

Query: 158 NISTTSVTARKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVAFGILKK 337
           ++S TS   R E D  G+++VP +  +G  T R++ NFP+ GI +     +I A+  +K+
Sbjct: 13  SMSETSNKTRLEHDCIGQMEVPANVYWGIHTQRAIGNFPVSGITDSQHPELIRAYATVKR 72

Query: 338 AAAKVNIEYGL-EKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIA 514
           A A  N E GL +   A+AI  AC ++ +GKL  +  FP+ + Q G+GT SNMN NEVIA
Sbjct: 73  ACAIANEELGLIDPAKAEAIRAACLEIEAGKLADQ--FPVDVMQGGAGTSSNMNMNEVIA 130

Query: 515 NRAIQILGGKLGSKDPVHPNDHVNKSQSSNDTYPTXMHIAV 637
           NRA++I G + G    +HPND VNKSQS+NDTYP    +A+
Sbjct: 131 NRALEIAGRQRGDYTYIHPNDDVNKSQSTNDTYPAACKLAL 171


>UniRef50_Q978Q5 Cluster: Fumarase; n=4; Thermoplasmatales|Rep:
           Fumarase - Thermoplasma volcanium
          Length = 457

 Score =  133 bits (322), Expect = 3e-30
 Identities = 68/157 (43%), Positives = 98/157 (62%), Gaps = 1/157 (0%)
 Frame = +2

Query: 185 RKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVAFGILKKAAAKVNIEY 364
           R E+D  GE+ + D   YG  T R+  NF I G+     +  IV+   +KKAAA  N E 
Sbjct: 2   RTERDVIGEIQLEDTVFYGINTARAKENFRITGLTSDSDH--IVSIAQIKKAAAMANAEA 59

Query: 365 G-LEKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIANRAIQILGG 541
           G L+K+ A+ I +ACD++ISG+ + +  F + ++Q G+GT  NMN NEVIAN A+ ++G 
Sbjct: 60  GALDKEKAEFIEKACDEIISGRYHDQ--FVIDVYQAGAGTSFNMNANEVIANVALTLMGK 117

Query: 542 KLGSKDPVHPNDHVNKSQSSNDTYPTXMHIAVAMELR 652
             G    +HPNDHVN SQS+ND YPT M + V  +++
Sbjct: 118 NKGDYSVIHPNDHVNMSQSTNDVYPTMMRLTVTKKVK 154


>UniRef50_Q938V7 Cluster: Aspartate ammonium lyase; n=1;
           Bradyrhizobium japonicum|Rep: Aspartate ammonium lyase -
           Bradyrhizobium japonicum
          Length = 466

 Score =  132 bits (318), Expect = 1e-29
 Identities = 70/157 (44%), Positives = 95/157 (60%), Gaps = 1/157 (0%)
 Frame = +2

Query: 182 ARKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVAFGILKKAAAKVNIE 361
           +R E+D  G+ ++ DD  YG QT+R   NF I GI        + A G +KKAAA  N +
Sbjct: 2   SRTEQDFLGQREIADDIYYGVQTIRGKENFHITGIPMNQEPYFVKALGYVKKAAAMANRD 61

Query: 362 YG-LEKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIANRAIQILG 538
            G ++ ++ADAI+  CD VI+G +  +  F     Q G+GT +NMN NEVIAN A++ LG
Sbjct: 62  LGVIDARVADAIILGCDRVIAGDMMDQ--FVTDFIQGGAGTSTNMNANEVIANLALESLG 119

Query: 539 GKLGSKDPVHPNDHVNKSQSSNDTYPTXMHIAVAMEL 649
            K G    V PNDHVN  QS+NDTYPT   +A+ + L
Sbjct: 120 FKKGDYQHVSPNDHVNYGQSTNDTYPTAFRLALILRL 156


>UniRef50_Q8FQP8 Cluster: Fumarate hydratase class II; n=35;
           Bacteria|Rep: Fumarate hydratase class II -
           Corynebacterium efficiens
          Length = 473

 Score =  131 bits (316), Expect = 2e-29
 Identities = 80/171 (46%), Positives = 104/171 (60%), Gaps = 1/171 (0%)
 Frame = +2

Query: 185 RKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVAFGILKKAAAKVNIEY 364
           R E DT GE+ VP   L+ AQT R+V NFPI G    +    I A G+LK A A+VN + 
Sbjct: 11  RIEHDTMGEVKVPAQALWRAQTQRAVENFPISG--RGLESAQIRAMGLLKAACAQVNKDS 68

Query: 365 G-LEKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIANRAIQILGG 541
           G L+   ADAI+ A  ++ +GK   +  FP+ ++QTGSGT SNMNTNEVIA+ A      
Sbjct: 69  GALDAAKADAIIAAGKEIATGK--HDAEFPIDVFQTGSGTSSNMNTNEVIASIA------ 120

Query: 542 KLGSKDPVHPNDHVNKSQSSNDTYPTXMHIAVAMELRDRLMPGLVXLRDTL 694
           K    + VHPND VN  QSSNDT+PT  H+A      + L+PGL  L ++L
Sbjct: 121 KANGTE-VHPNDDVNMGQSSNDTFPTATHVAATEAAVNDLIPGLKVLHESL 170


>UniRef50_A6DXB5 Cluster: Fumarate hydratase; n=1; Roseovarius sp.
           TM1035|Rep: Fumarate hydratase - Roseovarius sp. TM1035
          Length = 462

 Score =  130 bits (313), Expect = 4e-29
 Identities = 71/158 (44%), Positives = 98/158 (62%), Gaps = 2/158 (1%)
 Frame = +2

Query: 176 VTARKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIV-AFGILKKAAAKV 352
           +T R E D+ G++ +PDD LYG+ T R++ NF   G+     YP  + A  ++K+AAA  
Sbjct: 1   MTYRTESDSLGDVQLPDDTLYGSNTARALENFAGMGLP-LSAYPDFMRAMALVKRAAAMA 59

Query: 353 NIEYG-LEKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIANRAIQ 529
           N E G L   +ADAI+ ACD++++G       FP  + +   GT +NMN NEVIANRA Q
Sbjct: 60  NQEVGALASDVADAIIAACDEIVAGG--HADQFPTALLEGSGGTSTNMNFNEVIANRAGQ 117

Query: 530 ILGGKLGSKDPVHPNDHVNKSQSSNDTYPTXMHIAVAM 643
           ILG K G    V+PNDHVN SQS+ND  PT + +A  +
Sbjct: 118 ILGDKPGCYVRVNPNDHVNCSQSTNDALPTAVKLACVL 155


>UniRef50_P56149 Cluster: Aspartate ammonia-lyase; n=86; cellular
           organisms|Rep: Aspartate ammonia-lyase - Helicobacter
           pylori (Campylobacter pylori)
          Length = 468

 Score =  127 bits (306), Expect = 3e-28
 Identities = 71/170 (41%), Positives = 107/170 (62%), Gaps = 2/170 (1%)
 Frame = +2

Query: 185 RKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIV-AFGILKKAAAKVNIE 361
           R E D  G++++ D+  YG QT+R+  NF I   ++   YPV + +F  +KKAA   N++
Sbjct: 2   RIEHDFIGQMEISDEVYYGIQTLRASENFFITN-DKLCSYPVFIKSFAQVKKAATLANVQ 60

Query: 362 YGL-EKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIANRAIQILG 538
            GL ++K+  AI  ACD +I GK + +  F + + Q G+GT +NMN NEVIAN A++ +G
Sbjct: 61  LGLIDEKLKIAICHACDLLIDGKYHDQ--FIVDMIQGGAGTSTNMNMNEVIANLALEYMG 118

Query: 539 GKLGSKDPVHPNDHVNKSQSSNDTYPTXMHIAVAMELRDRLMPGLVXLRD 688
            + G     HPNDHVN+SQS+ND YP+ + IA+   L + + P +  LRD
Sbjct: 119 HQKGEYQFCHPNDHVNRSQSTNDAYPSALKIAIYERLSNLVAP-MKALRD 167


>UniRef50_Q010D6 Cluster: Fumarase; n=2; Eukaryota|Rep: Fumarase -
           Ostreococcus tauri
          Length = 524

 Score =  125 bits (301), Expect = 1e-27
 Identities = 78/175 (44%), Positives = 101/175 (57%)
 Frame = +2

Query: 170 TSVTARKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVAFGILKKAAAK 349
           T    R+E DT G +DVP  KL+GAQT RS+ NF IGG  E+MP  ++ +  I+K AAA 
Sbjct: 79  TEGETRRESDTMGVVDVPMHKLWGAQTQRSLENFKIGG--EKMPIAIVRSLAIVKYAAAT 136

Query: 350 VNIEYGLEKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIANRAIQ 529
           VN   G        ++ +C+D      +    FPLV      GTQ+NMN NEVI N    
Sbjct: 137 VNEREG-------RLLGSCED------HWMNTFPLVRVPNRIGTQTNMNLNEVICN---- 179

Query: 530 ILGGKLGSKDPVHPNDHVNKSQSSNDTYPTXMHIAVAMELRDRLMPGLVXLRDTL 694
                     P+HPNDHVN SQSSNDT+PT M IA A E+++RL+P L  L++ L
Sbjct: 180 ---------SPIHPNDHVNMSQSSNDTFPTAMSIATAHEVQERLIPALKMLQEAL 225


>UniRef50_A0RW57 Cluster: Fumarate hydratase/fumarase; n=3;
           Crenarchaeota|Rep: Fumarate hydratase/fumarase -
           Cenarchaeum symbiosum
          Length = 482

 Score =  124 bits (299), Expect = 2e-27
 Identities = 64/156 (41%), Positives = 101/156 (64%), Gaps = 2/156 (1%)
 Frame = +2

Query: 176 VTARKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIV-AFGILKKAAAKV 352
           V  R ++D+ G + +P D  YG  T R+   + + G      +P ++ A+ ++K++AA  
Sbjct: 30  VRYRTDEDSLGRVKIPADAYYGPFTARAAEQYRVTGTAA---HPALIEAYSMIKRSAAAA 86

Query: 353 NIEYG-LEKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIANRAIQ 529
           N + G L+ +   AI +ACD V+SG+ +R+  F + +  +G+GT  NMN NEVIAN A++
Sbjct: 87  NTKAGALDARRGRAITRACDMVLSGR-FRD-QFVIDMINSGAGTAFNMNANEVIANVALE 144

Query: 530 ILGGKLGSKDPVHPNDHVNKSQSSNDTYPTXMHIAV 637
           I G KLG  + +HPNDHVN SQS+NDT+PT MH+++
Sbjct: 145 IAGRKLGDYEYIHPNDHVNMSQSTNDTFPTAMHVSI 180


>UniRef50_Q9KNN3 Cluster: Aspartate ammonia-lyase; n=27;
           Bacteria|Rep: Aspartate ammonia-lyase - Vibrio cholerae
          Length = 483

 Score =  122 bits (295), Expect = 6e-27
 Identities = 68/159 (42%), Positives = 96/159 (60%), Gaps = 2/159 (1%)
 Frame = +2

Query: 167 TTSVTARKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVAFGILKKAAA 346
           T +   R E+D  G+  VP D  YG  T+R+V NF I  +        +    + KKAA 
Sbjct: 10  TATPATRVEEDLLGQRHVPADAYYGIHTLRAVENFNISNVTISDVPEFVRGMIMTKKAAT 69

Query: 347 KVNIEYG-LEKKIADAIMQACDDVI-SGKLYREGHFPLVIWQTGSGTQSNMNTNEVIANR 520
             N E G + K +A+ I+QACD ++ +GK   +  FP  ++Q G+GT  NMNTNEVIAN 
Sbjct: 70  LANKELGVIPKDVANYILQACDLILETGKCMDQ--FPSDVFQGGAGTSVNMNTNEVIANV 127

Query: 521 AIQILGGKLGSKDPVHPNDHVNKSQSSNDTYPTXMHIAV 637
           A++++G + G  + ++PNDHVNKSQS+N  YPT   IAV
Sbjct: 128 ALELMGKQKGQYEFINPNDHVNKSQSTNCAYPTGFRIAV 166


>UniRef50_P26899 Cluster: Aspartate ammonia-lyase; n=44;
           Bacteria|Rep: Aspartate ammonia-lyase - Bacillus
           subtilis
          Length = 475

 Score =  122 bits (293), Expect = 1e-26
 Identities = 70/161 (43%), Positives = 100/161 (62%), Gaps = 1/161 (0%)
 Frame = +2

Query: 185 RKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVAFGILKKAAAKVNIEY 364
           R EKD  GE  +  D  YG QT+R+  NFPI G   ++   +I A  I+KKAAA  N++ 
Sbjct: 9   RVEKDFLGEKQIEADVYYGIQTLRASENFPITGY--KIHEEMINALAIVKKAAALANMDV 66

Query: 365 G-LEKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIANRAIQILGG 541
             L + I  AI+QA D+++ GK + +  F +   Q G+GT  NMN NEVI NRA++I+G 
Sbjct: 67  KRLYEGIGQAIVQAADEILEGKWHDQ--FIVDPIQGGAGTSMNMNANEVIGNRALEIMGH 124

Query: 542 KLGSKDPVHPNDHVNKSQSSNDTYPTXMHIAVAMELRDRLM 664
           K G    + PN HVN SQS ND +PT +HI+  ++L ++L+
Sbjct: 125 KKGDYIHLSPNTHVNMSQSQNDVFPTAIHIS-TLKLLEKLL 164


>UniRef50_Q9WYS5 Cluster: Aspartate ammonia-lyase; n=4;
           Thermotogaceae|Rep: Aspartate ammonia-lyase - Thermotoga
           maritima
          Length = 458

 Score =  120 bits (290), Expect = 3e-26
 Identities = 73/171 (42%), Positives = 107/171 (62%), Gaps = 1/171 (0%)
 Frame = +2

Query: 185 RKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVAFGILKKAAAKVNIEY 364
           RKE+D  G+L++  +  YG  T R++MNFP  G  E++    I A+ ++KKA A +N E 
Sbjct: 2   RKERDYLGKLEIEGEVYYGIHTKRALMNFPSTG--EKLDETFIWAYFMVKKACALLNTEL 59

Query: 365 G-LEKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIANRAIQILGG 541
           G L+++  +AI++ACD+    K     H  +     G+GT  NMN NEVIANRA +ILGG
Sbjct: 60  GYLDERTGNAIVKACDEWEDLKK----HVVVDPLSGGAGTSINMNVNEVIANRATEILGG 115

Query: 542 KLGSKDPVHPNDHVNKSQSSNDTYPTXMHIAVAMELRDRLMPGLVXLRDTL 694
           K G +  V P DHVN  QS+NDT+PT   IA  ++LR RL+  ++ L++ +
Sbjct: 116 KKG-EYLVDPIDHVNLHQSTNDTFPTSAKIATIVKLR-RLIDEVINLQEKI 164


>UniRef50_Q30VF1 Cluster: Aspartate ammonia-lyase, putative; n=1;
           Desulfovibrio desulfuricans G20|Rep: Aspartate
           ammonia-lyase, putative - Desulfovibrio desulfuricans
           (strain G20)
          Length = 490

 Score =  120 bits (288), Expect = 4e-26
 Identities = 65/156 (41%), Positives = 92/156 (58%), Gaps = 1/156 (0%)
 Frame = +2

Query: 185 RKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVAFGILKKAAAKVNIEY 364
           R E D  G  ++P D LYG  T+R+  NFP+     R+  P+I A   +K A A+ N   
Sbjct: 2   RTEHDALGSRELPADALYGIHTLRAAENFPVSPY--RLAPPLIRALAQVKLACARTNARL 59

Query: 365 G-LEKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIANRAIQILGG 541
           G L+ ++A+AI  AC ++I G    +  F    +Q G+GT +NMN NEV+ANRA Q+LGG
Sbjct: 60  GYLDNRLAEAIETACLEIIGGS--HQDSFITDPFQGGAGTSANMNMNEVVANRACQLLGG 117

Query: 542 KLGSKDPVHPNDHVNKSQSSNDTYPTXMHIAVAMEL 649
             G    V P +HVN  QS+ND +PT + +A+  EL
Sbjct: 118 VPGQHSLVSPLNHVNMHQSTNDVFPTALRVAMLHEL 153


>UniRef50_A1B109 Cluster: Aspartate ammonia-lyase; n=1; Paracoccus
           denitrificans PD1222|Rep: Aspartate ammonia-lyase -
           Paracoccus denitrificans (strain Pd 1222)
          Length = 455

 Score =  119 bits (286), Expect = 8e-26
 Identities = 60/152 (39%), Positives = 92/152 (60%), Gaps = 1/152 (0%)
 Frame = +2

Query: 185 RKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVAFGILKKAAAKVNIEY 364
           R E D  G   +P + LYG  T+R+  NFP+ G++     P+I A  + KKAAA  N   
Sbjct: 9   RIESDELGSRRLPGEALYGINTLRAAENFPVSGMKIGSLAPLIRAMALTKKAAAAANYRL 68

Query: 365 G-LEKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIANRAIQILGG 541
           G L  + A+ I + CD++++G+    GHF + ++Q G GT S+MN NEVIANR ++++G 
Sbjct: 69  GKLSARKAEVIGRVCDELMAGQ--HAGHFVIDVFQGGGGTSSHMNLNEVIANRGLELMGR 126

Query: 542 KLGSKDPVHPNDHVNKSQSSNDTYPTXMHIAV 637
             G  + +HP   VN+SQS+ D + T + IA+
Sbjct: 127 ACGQYEHLHPIRDVNRSQSTTDVHATALRIAL 158


>UniRef50_Q00SM0 Cluster: Aspartate ammonia-lyase; n=4; cellular
           organisms|Rep: Aspartate ammonia-lyase - Ostreococcus
           tauri
          Length = 559

 Score =  118 bits (285), Expect = 1e-25
 Identities = 65/157 (41%), Positives = 90/157 (57%), Gaps = 2/157 (1%)
 Frame = +2

Query: 179 TARKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIV-AFGILKKAAAKVN 355
           + R E D  G +++P   LYG  T R++ N+ I G      YP +V A  + KKA A  N
Sbjct: 76  STRTESDLLGTMEIPSHALYGIATARAMENYDITG-NRLSKYPELVRALALTKKACATAN 134

Query: 356 IEYGL-EKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIANRAIQI 532
              GL + ++ +AI  ACD +I    +   HF + + Q G+GT +NMN NEVIAN A + 
Sbjct: 135 RRIGLLDNEVYEAITHACDALIESSEHHH-HFTVDVIQGGAGTSTNMNANEVIANLAARK 193

Query: 533 LGGKLGSKDPVHPNDHVNKSQSSNDTYPTXMHIAVAM 643
           LG  +G    V+PNDHVN  QS+ND YPT   +AV +
Sbjct: 194 LGLPIGDYAVVNPNDHVNLCQSTNDAYPTAAKLAVVL 230


>UniRef50_P07346 Cluster: Aspartate ammonia-lyase; n=22;
           Bacteria|Rep: Aspartate ammonia-lyase - Pseudomonas
           fluorescens
          Length = 478

 Score =  118 bits (285), Expect = 1e-25
 Identities = 65/173 (37%), Positives = 103/173 (59%), Gaps = 1/173 (0%)
 Frame = +2

Query: 158 NISTTSVTARKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVAFGILKK 337
           ++ +++ + R EKD  G L+VP    YG QT+R+V NF + G+       ++V   ++K+
Sbjct: 3   SVMSSAASFRTEKDLLGVLEVPAQAYYGIQTLRAVNNFRLSGVPISHYPKLVVGLAMVKQ 62

Query: 338 AAAKVNIEYG-LEKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIA 514
           AAA  N E G L ++   AI +AC  +I G  + E  F + + Q G+GT +NMN NEVIA
Sbjct: 63  AAADANRELGQLSERKHAAISEACARLIRGDFHEE--FVVDMIQGGAGTSTNMNANEVIA 120

Query: 515 NRAIQILGGKLGSKDPVHPNDHVNKSQSSNDTYPTXMHIAVAMELRDRLMPGL 673
           N A++ +G + G    +HPN+ VN +QS+ND YPT + + + +   D L+  L
Sbjct: 121 NIALEAMGHQKGEYQYLHPNNDVNMAQSTNDAYPTAIRLGLLLG-HDALLASL 172


>UniRef50_P39461 Cluster: Fumarate hydratase class II; n=10;
           Thermoprotei|Rep: Fumarate hydratase class II -
           Sulfolobus solfataricus
          Length = 438

 Score =  115 bits (276), Expect = 1e-24
 Identities = 66/135 (48%), Positives = 86/135 (63%), Gaps = 1/135 (0%)
 Frame = +2

Query: 293 RMPYPVIVAFGILKKAAAKVNIEYGL-EKKIADAIMQACDDVISGKLYREGHFPLVIWQT 469
           + P  +I + G+LKK+ AKVN + GL +KKIAD+I++A DD+I GKL  +    L ++QT
Sbjct: 17  KFPRRIIWSMGVLKKSCAKVNADLGLLDKKIADSIIKASDDLIDGKL--DDKIVLDVFQT 74

Query: 470 GSGTQSNMNTNEVIANRAIQILGGKLGSKDPVHPNDHVNKSQSSNDTYPTXMHIAVAMEL 649
           GSGT  NMN NEVIA  A      K      VHPNDHVN  QSSNDT PT + IA   E+
Sbjct: 75  GSGTGLNMNVNEVIAEVASSYSNLK------VHPNDHVNFGQSSNDTVPTAIRIAAVAEV 128

Query: 650 RDRLMPGLVXLRDTL 694
            +RL+P L  +  +L
Sbjct: 129 TNRLLPALQQIISSL 143


>UniRef50_Q88TT7 Cluster: Aspartate ammonia-lyase; n=2;
           Lactobacillus|Rep: Aspartate ammonia-lyase -
           Lactobacillus plantarum
          Length = 466

 Score =  112 bits (270), Expect = 7e-24
 Identities = 74/172 (43%), Positives = 104/172 (60%), Gaps = 2/172 (1%)
 Frame = +2

Query: 185 RKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVAFGI-LKKAAAKVNIE 361
           R E D  G+L VPDD LYG  T+R+V NFPI      + +P+I+   + +KKAAA VN  
Sbjct: 2   RIEADCIGKLAVPDDALYGIHTLRAVHNFPI---TTELMHPLIMQSLVQIKKAAASVNAA 58

Query: 362 YG-LEKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIANRAIQILG 538
            G L    A AI+ AC+ ++ G+ Y + +F +   Q G+GT +NMN NEV+AN A +++ 
Sbjct: 59  AGTLSNDKAHAIIAACNQLLLGR-YAD-NFIVPAIQGGAGTSANMNVNEVVANLAHRLMP 116

Query: 539 GKLGSKDPVHPNDHVNKSQSSNDTYPTXMHIAVAMELRDRLMPGLVXLRDTL 694
                   VHPND VN+SQS+NDT+PT   +A+ M+L   L+  L  L  TL
Sbjct: 117 AVA-----VHPNDDVNQSQSTNDTFPTAGKMALCMQL-PGLLTALSRLVQTL 162


>UniRef50_Q74IW1 Cluster: Fumarate hydratase; n=4; Bacteria|Rep:
           Fumarate hydratase - Lactobacillus johnsonii
          Length = 468

 Score =  110 bits (265), Expect = 3e-23
 Identities = 71/168 (42%), Positives = 97/168 (57%), Gaps = 2/168 (1%)
 Frame = +2

Query: 185 RKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVAFGILKKAAAKVNIEY 364
           R E DT G +++P   L+G QT RS  NF  G +   MP  +I A   +K AAA+ NIE 
Sbjct: 7   RVESDTLGPVEIPKKALWGPQTQRSKDNFHTGAL---MPIGIIRALLQIKLAAAQANIEA 63

Query: 365 GLE-KKIADAIMQACDDVIS-GKLYREGHFPLVIWQTGSGTQSNMNTNEVIANRAIQILG 538
           G E ++   AI++A   ++       + +FPL ++QTGSGTQ+NMN NEV+AN     L 
Sbjct: 64  GTETEEKGRAIIEAIHQLLDLNNEELQPYFPLHVYQTGSGTQTNMNVNEVVAN-----LA 118

Query: 539 GKLGSKDPVHPNDHVNKSQSSNDTYPTXMHIAVAMELRDRLMPGLVXL 682
            K      + PND VN  QSSNDT+PT M++ VA +  D L P +  L
Sbjct: 119 NKNHPGLDILPNDDVNMGQSSNDTFPTAMNL-VATQALDDLKPSIKHL 165


>UniRef50_Q59200 Cluster: Aspartate ammonia-lyase; n=117;
           Bacteria|Rep: Aspartate ammonia-lyase - Corynebacterium
           glutamicum (Brevibacterium flavum)
          Length = 526

 Score =  110 bits (264), Expect = 4e-23
 Identities = 62/159 (38%), Positives = 88/159 (55%), Gaps = 1/159 (0%)
 Frame = +2

Query: 164 STTSVTARKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVAFGILKKAA 343
           +T     R E D  GEL +P    YG  T+R+V NF I           I     +KKAA
Sbjct: 50  TTVQKKFRIESDLLGELQIPSHAYYGVHTLRAVDNFQISRTTINHVPDFIRGMVQVKKAA 109

Query: 344 AKVNIE-YGLEKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIANR 520
           A  N   + L  + A+AI+ ACD ++  +   +  FP+ ++Q G+GT  NMNTNEV+AN 
Sbjct: 110 ALANRRLHTLPAQKAEAIVWACDQILIEERCMD-QFPIDVFQGGAGTSLNMNTNEVVANL 168

Query: 521 AIQILGGKLGSKDPVHPNDHVNKSQSSNDTYPTXMHIAV 637
           A++ LG + G    +HP D VN SQS+ND+YPT   + +
Sbjct: 169 ALEFLGHEKGEYHILHPMDDVNMSQSTNDSYPTGFRLGI 207


>UniRef50_A3Y7G3 Cluster: Hypothetical aspartate ammonia-lyase; n=2;
           Proteobacteria|Rep: Hypothetical aspartate ammonia-lyase
           - Marinomonas sp. MED121
          Length = 473

 Score =  101 bits (241), Expect = 2e-20
 Identities = 62/158 (39%), Positives = 86/158 (54%), Gaps = 1/158 (0%)
 Frame = +2

Query: 185 RKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVAFGILKKAAAKVNIEY 364
           R E D  GE  + +   YG QT+R+  NF I G         + +   +KKAAA  N + 
Sbjct: 2   RIEHDALGERQLEETLYYGIQTLRAKENFDISGKTISNIPSFVESIIQIKKAAAMANHKA 61

Query: 365 G-LEKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIANRAIQILGG 541
             L++ +  AI QA D++++       +F + I+  G GT +NMN NEV+ANRA +I+ G
Sbjct: 62  QVLDENLCKAICQAADEMLANP--DPANFVVDIYHGGGGTSANMNINEVLANRANEIMTG 119

Query: 542 KLGSKDPVHPNDHVNKSQSSNDTYPTXMHIAVAMELRD 655
             G  D VHPN HVN  QS+ND  P  M +AV   L D
Sbjct: 120 HKGY-DQVHPNTHVNMGQSTNDVIPAAMKMAVFNSLND 156


>UniRef50_UPI0000510540 Cluster: COG1027: Aspartate ammonia-lyase;
           n=1; Brevibacterium linens BL2|Rep: COG1027: Aspartate
           ammonia-lyase - Brevibacterium linens BL2
          Length = 160

 Score = 93.9 bits (223), Expect = 3e-18
 Identities = 53/138 (38%), Positives = 83/138 (60%), Gaps = 2/138 (1%)
 Frame = +2

Query: 167 TTSVTARKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIV-AFGILKKAA 343
           + S   R E D+ G L++P    +G  T R++ NFPI      + YP  V AF  +K+AA
Sbjct: 23  SVSTPTRTETDSIGSLEIPAAAYWGVHTARAMENFPIARRPVSV-YPDFVRAFACVKQAA 81

Query: 344 AKVNIEYG-LEKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIANR 520
           A+ N+E G L+++ A+ I  AC+++  G+L+ +  F + + Q G+GT +NMN NEVI NR
Sbjct: 82  ARANLEIGALDEQRANLIDAACEEIKGGRLHDQ--FTVGVIQGGAGTSTNMNANEVITNR 139

Query: 521 AIQILGGKLGSKDPVHPN 574
           A++I G   G    ++PN
Sbjct: 140 ALEIGGHAKGDYSFINPN 157


>UniRef50_A3SJ56 Cluster: Aspartate ammonia-lyase; n=1; Roseovarius
           nubinhibens ISM|Rep: Aspartate ammonia-lyase -
           Roseovarius nubinhibens ISM
          Length = 446

 Score = 90.2 bits (214), Expect = 4e-17
 Identities = 58/144 (40%), Positives = 78/144 (54%), Gaps = 2/144 (1%)
 Frame = +2

Query: 218 VPDDKLYGAQTVRSVMNFP-IGGIEERMPYPVIVAFGILKKAAAKVNIEYG-LEKKIADA 391
           +P+  LYGA T R   NF   G      PY +    G+ K+AAA+ N   G L  + ADA
Sbjct: 1   MPEASLYGANTARGAANFKGFGPTLADYPYFMRAMAGV-KQAAARANQSVGALIDRHADA 59

Query: 392 IMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIANRAIQILGGKLGSKDPVHP 571
           I  ACD++  G  + +   PL   +   GT +NMN NEVIA RA QI+G    +   V  
Sbjct: 60  IADACDEIRDGAHWDQFIVPLA--EGSGGTSTNMNFNEVIAARANQIMGLAQDAPGGVTA 117

Query: 572 NDHVNKSQSSNDTYPTXMHIAVAM 643
           NDHVN +QS+ND  PT + +A  +
Sbjct: 118 NDHVNLAQSTNDCVPTGIKLACVL 141


>UniRef50_A4NYC4 Cluster: Fumarate hydratase; n=1; Haemophilus
           influenzae 22.4-21|Rep: Fumarate hydratase - Haemophilus
           influenzae 22.4-21
          Length = 139

 Score = 82.6 bits (195), Expect = 8e-15
 Identities = 39/67 (58%), Positives = 48/67 (71%)
 Frame = +2

Query: 491 MNTNEVIANRAIQILGGKLGSKDPVHPNDHVNKSQSSNDTYPTXMHIAVAMELRDRLMPG 670
           MN NEV+ANRA  I GGKLG K  +HPND VNKSQSSNDT+PT MHIA   ++ +  +P 
Sbjct: 1   MNVNEVVANRAHVINGGKLGEKSIIHPNDDVNKSQSSNDTFPTAMHIAAYKKVVEHTIPC 60

Query: 671 LVXLRDT 691
           +  L+ T
Sbjct: 61  VERLQKT 67


>UniRef50_UPI0000499E1B Cluster: aspartase-related; n=1; Entamoeba
           histolytica HM-1:IMSS|Rep: aspartase-related - Entamoeba
           histolytica HM-1:IMSS
          Length = 152

 Score = 77.8 bits (183), Expect = 2e-13
 Identities = 47/113 (41%), Positives = 65/113 (57%), Gaps = 1/113 (0%)
 Frame = +2

Query: 182 ARKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVAFGILKKAAAKVNIE 361
           ++  KD+ GE+ VP D  YGAQT+R+  NFPI     ++    I AFG +K+A A  N  
Sbjct: 42  SKNMKDSLGEVQVPKDAYYGAQTMRATKNFPI--THHKVDPDFIHAFGYVKEATAYANCV 99

Query: 362 YG-LEKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIAN 517
            G L+K+ AD IM+A  ++  GK         +  Q G+GT  NMN NE+IAN
Sbjct: 100 DGILDKEKADYIMKAARELAEGKFDESVVVDPI--QGGAGTSLNMNCNEIIAN 150


>UniRef50_A0VSJ0 Cluster: Putative uncharacterized protein; n=3;
           Rhodobacteraceae|Rep: Putative uncharacterized protein -
           Dinoroseobacter shibae DFL 12
          Length = 697

 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 54/127 (42%), Positives = 68/127 (53%), Gaps = 1/127 (0%)
 Frame = -1

Query: 568 MHRVLAAQFPAQYLYGAVRNHLVRVHVGLSTGASLPDDEGEVTLAVELPADDVIAGLHDR 389
           MHRVL A   AQ L  AV +HLV VHVGL  GA LPD + EV   VEL  D +  GL DR
Sbjct: 410 MHRVLGADHAAQDLDRAVGDHLVGVHVGLGAGAGLPDHQREV--VVELAVDHLARGLDDR 467

Query: 388 VGNF-LFKSIFDIDFGGCFL*YTESDNHGIRHAFLNSTDREVHHRTHGLRAI*LVIWHVQ 212
           +G   +  + F +  G   L + E  N   RH  L  +D EVH R   LRA  LV  +++
Sbjct: 468 IGQAGVELAAFLVGHGAGLLDHAEGAND--RHGLLFPSDGEVHDRALRLRAPILVGRNLE 525

Query: 211 LPKGIFF 191
             + + F
Sbjct: 526 RAEAVGF 532


>UniRef50_Q1LB63 Cluster: Fumarate hydratase, class II; n=1;
           Ralstonia metallidurans CH34|Rep: Fumarate hydratase,
           class II - Ralstonia metallidurans (strain CH34 / ATCC
           43123 / DSM 2839)
          Length = 98

 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 44/89 (49%), Positives = 57/89 (64%), Gaps = 1/89 (1%)
 Frame = +2

Query: 161 ISTTSVTARKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVAFGILKKA 340
           +S  S   R EKD+ G++ VP D L+GAQT RS  NF IG   E+MP  +I AF ILK  
Sbjct: 1   MSEKSSATRIEKDSLGDVAVPADHLWGAQTERSRQNFRIG--SEKMPPALIEAFAILKLC 58

Query: 341 AAKVNIEYG-LEKKIADAIMQACDDVISG 424
           AA+ N E G L+  +ADAI +A ++VI G
Sbjct: 59  AARANRELGVLKPDLADAIERAAEEVIGG 87


>UniRef50_Q12ZL4 Cluster: Fumarate hydratase class II; n=1;
           Methanococcoides burtonii DSM 6242|Rep: Fumarate
           hydratase class II - Methanococcoides burtonii (strain
           DSM 6242)
          Length = 92

 Score = 70.9 bits (166), Expect = 3e-11
 Identities = 38/83 (45%), Positives = 53/83 (63%), Gaps = 1/83 (1%)
 Frame = +2

Query: 185 RKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVAFGILKKAAAKVNIEY 364
           R E+DT GE++VP+D  YG QTVR++ NF I    +R+P   I A   +K A+A+ N+E 
Sbjct: 7   RSERDTLGEIEVPEDVYYGPQTVRTINNFKIS--RQRLPSSFIRAQAAIKLASARANLEA 64

Query: 365 G-LEKKIADAIMQACDDVISGKL 430
           G LE +IA AI+ A  +V  G L
Sbjct: 65  GKLEPEIAKAIISAASEVREGNL 87


>UniRef50_Q4J197 Cluster: Putative uncharacterized protein; n=1;
           Azotobacter vinelandii AvOP|Rep: Putative
           uncharacterized protein - Azotobacter vinelandii AvOP
          Length = 489

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 42/106 (39%), Positives = 54/106 (50%), Gaps = 2/106 (1%)
 Frame = -1

Query: 568 MHRVLAAQFPAQYLYGAVRNHLVRVHVGLSTGASLPDDEGEVTLAVELPADDVIAGLHDR 389
           +HR LA    A  L GA  +H V VHV L   A LPD + E  L V L  + ++ GL D+
Sbjct: 356 VHRALAPARAAGQLVGAPGDHFVDVHVALGAAAGLPDHQRE--LPVVLAGEYLVGGLLDQ 413

Query: 388 VGNFLFKSIFD--IDFGGCFL*YTESDNHGIRHAFLNSTDREVHHR 257
            G+F  + + D  +D GG  L   +   HG RHA L   D EV  R
Sbjct: 414 PGDFR-RQLADAVVDSGGGLLDQRQGVQHGERHALL--ADGEVDQR 456


>UniRef50_A4NYC9 Cluster: Fumarate hydratase; n=1; Haemophilus
           influenzae 22.4-21|Rep: Fumarate hydratase - Haemophilus
           influenzae 22.4-21
          Length = 61

 Score = 54.4 bits (125), Expect = 3e-06
 Identities = 29/51 (56%), Positives = 33/51 (64%)
 Frame = +2

Query: 185 RKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVAFGILKK 337
           R EKDT GE+ VP DK + AQT RS  NF IG     MP+ +I AFG LKK
Sbjct: 4   RIEKDTMGEVQVPADKYWAAQTERSRNNFKIGPAAS-MPHEIIEAFGYLKK 53


>UniRef50_A5NX44 Cluster: Putative uncharacterized protein; n=1;
           Methylobacterium sp. 4-46|Rep: Putative uncharacterized
           protein - Methylobacterium sp. 4-46
          Length = 537

 Score = 53.2 bits (122), Expect = 6e-06
 Identities = 35/97 (36%), Positives = 43/97 (44%)
 Frame = -1

Query: 673 EARHEPVPEXXXXXXXXXXXXXXXXXXXXXXXXXGMHRVLAAQFPAQYLYGAVRNHLVRV 494
           E RH+PV +                          +HR LAA  PA+ L G  R+HLV V
Sbjct: 358 ERRHQPVADLAGHRDVHRGRERVVRGLAAVDVVVRVHRRLAAALPAEPLVGEARDHLVGV 417

Query: 493 HVGLSTGASLPDDEGEVTLAVELPADDVIAGLHDRVG 383
           HV L   A LPD + E  LAV  P D +  G  D +G
Sbjct: 418 HVRLRARAGLPDHQRE--LAVVAPLDHLGGGGRDGLG 452


>UniRef50_A0U0K7 Cluster: Putative uncharacterized protein; n=1;
           Burkholderia cenocepacia MC0-3|Rep: Putative
           uncharacterized protein - Burkholderia cenocepacia MC0-3
          Length = 495

 Score = 52.8 bits (121), Expect = 8e-06
 Identities = 47/126 (37%), Positives = 56/126 (44%), Gaps = 2/126 (1%)
 Frame = -1

Query: 550 AQFPAQYLYGAVRNHLVRVHVGLSTGASLPDDEGEVTLAVELPADDVIAGLHDRVGNFLF 371
           A   AQ L  AVRNHLV VHVGL  GA LP  + E   A  L  DD++ G  DRV   + 
Sbjct: 307 AALAAQQLARAVRNHLVEVHVGLRAGARLPHRQRE--FARMLAGDDLVGGFDDRVRLVVG 364

Query: 370 KSIFDIDFG--GCFL*YTESDNHGIRHAFLNSTDREVHHRTHGLRAI*LVIWHVQLPKGI 197
           +    +  G  G        D  G     L   D E+  R  GLRA   V  H  L + +
Sbjct: 365 EHAERLVDGRRGALDDRERVDQLG---RLLLRRDPEILQRALGLRAPEPVGRHGDLAERV 421

Query: 196 FFLPRC 179
            F P C
Sbjct: 422 AFHPNC 427


>UniRef50_A7DHF3 Cluster: Putative uncharacterized protein
           precursor; n=2; Methylobacterium extorquens PA1|Rep:
           Putative uncharacterized protein precursor -
           Methylobacterium extorquens PA1
          Length = 574

 Score = 43.6 bits (98), Expect = 0.005
 Identities = 36/117 (30%), Positives = 52/117 (44%), Gaps = 1/117 (0%)
 Frame = -1

Query: 688 VPEXHEARHEPVPEXXXXXXXXXXXXXXXXXXXXXXXXXGMHRVLAAQFPAQYLYGAVRN 509
           VP+  + R EP+P+                         GMH +LA +     L G VR+
Sbjct: 323 VPQLGDGRREPLPDCDRGGHVHRRREGVVRRLGHVDVVVGMHGILAPERLTGDLAGPVRD 382

Query: 508 HLVRVHVGLSTGASLPDDEGEVTLAVELPADDVIAGLHDR-VGNFLFKSIFDIDFGG 341
           HLV VHV L   A  PD + +  L V L   +++A L+D  V      +I ++D GG
Sbjct: 383 HLVDVHVELGAAARHPDVQRK-HLRV-LSGQNLVADLNDELVLGLAEAAIREVDVGG 437


>UniRef50_UPI0000499F8A Cluster: aspartate ammonia-lyase; n=1;
           Entamoeba histolytica HM-1:IMSS|Rep: aspartate
           ammonia-lyase - Entamoeba histolytica HM-1:IMSS
          Length = 344

 Score = 41.5 bits (93), Expect = 0.019
 Identities = 19/36 (52%), Positives = 25/36 (69%)
 Frame = +2

Query: 557 DPVHPNDHVNKSQSSNDTYPTXMHIAVAMELRDRLM 664
           D + PN HVN SQS+ND +PT  HIA   ++ DRL+
Sbjct: 9   DIISPNTHVNMSQSTNDAFPTAFHIAGLWKI-DRLI 43


>UniRef50_A5NPW1 Cluster: Putative uncharacterized protein; n=1;
           Methylobacterium sp. 4-46|Rep: Putative uncharacterized
           protein - Methylobacterium sp. 4-46
          Length = 581

 Score = 40.3 bits (90), Expect = 0.044
 Identities = 22/44 (50%), Positives = 29/44 (65%)
 Frame = -1

Query: 517 VRNHLVRVHVGLSTGASLPDDEGEVTLAVELPADDVIAGLHDRV 386
           V +HLV VHVG   GA+L  D+ +  L VE PA D++AG  DR+
Sbjct: 398 VGDHLVGVHVGRGAGAAL--DQVDHELVVERPAADLLAGRDDRL 439


>UniRef50_A1G5B1 Cluster: Putative uncharacterized protein; n=1;
           Salinispora arenicola CNS205|Rep: Putative
           uncharacterized protein - Salinispora arenicola CNS205
          Length = 523

 Score = 40.3 bits (90), Expect = 0.044
 Identities = 41/129 (31%), Positives = 55/129 (42%), Gaps = 1/129 (0%)
 Frame = -1

Query: 568 MHRVLAAQFPAQYLYGAVRNHLVRVHVGLSTGASLPDDEGEVTLAVELPADDVIAGLHDR 389
           +H V+     AQ   G   +HLV VHV   TG  L D + E  L V      V +G  DR
Sbjct: 366 VHIVVGVHVGAQLTTGQSGDHLVGVHVRRRTGTGLEDVDRE--LVVVPAVGHVRSGGGDR 423

Query: 388 VGNF-LFKSIFDIDFGGCFL*YTESDNHGIRHAFLNSTDREVHHRTHGLRAI*LVIWHVQ 212
            G+  +    F +D G   L   +  + G    +    DREV HR  GLR    +  H+ 
Sbjct: 424 GGHIRIDHPQFTVDLGRGSLDLRQRPDLG--RFYPPPGDREVLHRALGLRPPQRLGGHLH 481

Query: 211 LPKGIFFLP 185
           L   + F P
Sbjct: 482 LTHRVTFDP 490


>UniRef50_A0VGM0 Cluster: Putative uncharacterized protein; n=3;
           Burkholderiales|Rep: Putative uncharacterized protein -
           Delftia acidovorans SPH-1
          Length = 513

 Score = 39.1 bits (87), Expect = 0.10
 Identities = 39/112 (34%), Positives = 50/112 (44%), Gaps = 1/112 (0%)
 Frame = -1

Query: 520 AVRNHLVRVHVGLSTGASLPDDEGEVTLAVELPADDVIAGLHDRVGNFLFKSI-FDIDFG 344
           AV  HLV VHVGL   A LPD + E  L   L  D ++ G  D +G  L +     +D G
Sbjct: 357 AVGQHLVDVHVGLRARAGLPDHQRE--LVRVLAGDHLVGGGQDGLGLLLVQQAQLVVDGG 414

Query: 343 GCFL*YTESDNHGIRHAFLNSTDREVHHRTHGLRAI*LVIWHVQLPKGIFFL 188
              L   +  +   R   L + D EV  RT  LR   LV       + +FFL
Sbjct: 415 RGLLDLGQRVDDLAR--LLLAADVEVLQRTLRLRTPELVCGDGYGSESVFFL 464


>UniRef50_A3HI19 Cluster: Putative uncharacterized protein; n=2;
           Pseudomonas putida|Rep: Putative uncharacterized protein
           - Pseudomonas putida (strain GB-1)
          Length = 591

 Score = 37.9 bits (84), Expect = 0.23
 Identities = 39/115 (33%), Positives = 52/115 (45%), Gaps = 2/115 (1%)
 Frame = -1

Query: 535 QYLYGAVRNHLVRVHVGLSTGASLPDDEGEVTLAV--ELPADDVIAGLHDRVGNFLFKSI 362
           QY  G  R+H V VHV    GA L   + E+   V  +   D +  GL  R G  LF+  
Sbjct: 363 QYAAGQGRDHFVGVHVRAGAGAGLEHIDREMLDEVFGQQLLDSLDDGLALR-GGQLFQ-- 419

Query: 361 FDIDFGGCFL*YTESDNHGIRHAFLNSTDREVHHRTHGLRAI*LVIWHVQLPKGI 197
            D+  G   L   +S N   RHA   + DREV  R  GL A+  +  H+Q    +
Sbjct: 420 LDVGLGRGCLGQQQSTNELGRHAL--AADREVVDRALGLGAVQGLGRHLQFTHAV 472


>UniRef50_A0TG73 Cluster: RNA binding protein, putative; n=2;
           Burkholderia cepacia complex|Rep: RNA binding protein,
           putative - Burkholderia ambifaria MC40-6
          Length = 514

 Score = 37.9 bits (84), Expect = 0.23
 Identities = 21/56 (37%), Positives = 26/56 (46%)
 Frame = +1

Query: 433 PRGSLPPRHLADWLRYSVQHEHERGDCEPRHTNTGRETGQQGPGASQRPREQVAEL 600
           P G  P  H AD  R   +H  E  D +P H   GRE G++ PG  +  R    EL
Sbjct: 164 PVGEDPAEHHAD-RRGDERHHREEADLQPAHVALGREIGRE-PGQEEHERRVAGEL 217


>UniRef50_UPI00015B53F3 Cluster: PREDICTED: hypothetical protein;
           n=1; Nasonia vitripennis|Rep: PREDICTED: hypothetical
           protein - Nasonia vitripennis
          Length = 709

 Score = 35.9 bits (79), Expect = 0.94
 Identities = 20/89 (22%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
 Frame = +2

Query: 392 IMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIANR--AIQILGGKLGSKDPV 565
           IM    + + G L++E  +P + W TGS  +  + +   +AN   AI ++G  L     +
Sbjct: 481 IMDEVSETLKGLLFQEAGYPWIHWSTGSVDKPRLASTLKVANASVAIAMMGMMLPGTPSI 540

Query: 566 HPNDHVNKSQSSNDTYPTXMHIAVAMELR 652
              D +    S +  +    H+   + +R
Sbjct: 541 FYGDEIGMLNSESKEHQDLNHLYQLVPMR 569


>UniRef50_A7D1M8 Cluster: Putative uncharacterized protein; n=1;
           Halorubrum lacusprofundi ATCC 49239|Rep: Putative
           uncharacterized protein - Halorubrum lacusprofundi ATCC
           49239
          Length = 584

 Score = 35.5 bits (78), Expect = 1.2
 Identities = 24/56 (42%), Positives = 29/56 (51%)
 Frame = -1

Query: 550 AQFPAQYLYGAVRNHLVRVHVGLSTGASLPDDEGEVTLAVELPADDVIAGLHDRVG 383
           A   A+ L GAV + LV VHV    GA L   + E  L V +  DD + G  DRVG
Sbjct: 374 ADLRARDLGGAVGDDLVCVHVRRGAGACLEHVDRE--LVVVVAGDDFVGGSDDRVG 427


>UniRef50_Q0CRV8 Cluster: Predicted protein; n=1; Aspergillus
           terreus NIH2624|Rep: Predicted protein - Aspergillus
           terreus (strain NIH 2624)
          Length = 2558

 Score = 33.5 bits (73), Expect = 5.0
 Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 1/83 (1%)
 Frame = +2

Query: 155 RNISTTSVTARKEKDTFGELDVPDDKLYGAQTVRSVM-NFPIGGIEERMPYPVIVAFGIL 331
           R     +V A   + T+ ELDV  D L     +R +    PI    ER    V+   GI+
Sbjct: 338 RRPDAAAVHAWDGQATYHELDVMSDNLAHELLLRKISPEVPIAFTLERSLSAVVAVLGIM 397

Query: 332 KKAAAKVNIEYGLEKKIADAIMQ 400
           K   A + IE    +   DAI++
Sbjct: 398 KAGGACLPIELSFPRARKDAIVR 420


>UniRef50_Q6UWB1 Cluster: Interleukin-27 receptor subunit alpha
           precursor; n=19; Eutheria|Rep: Interleukin-27 receptor
           subunit alpha precursor - Homo sapiens (Human)
          Length = 636

 Score = 33.1 bits (72), Expect = 6.6
 Identities = 14/30 (46%), Positives = 17/30 (56%), Gaps = 2/30 (6%)
 Frame = -3

Query: 572 WDAPGPCCPVSRPVFVWRGSQ--SPRSCSC 489
           W APGPC  VS  V+ W G +  SP   +C
Sbjct: 255 WKAPGPCVQVSYKVWFWVGGRELSPEGITC 284


>UniRef50_Q39PM2 Cluster: Putative uncharacterized protein; n=1;
           Burkholderia sp. 383|Rep: Putative uncharacterized
           protein - Burkholderia sp. (strain 383) (Burkholderia
           cepacia (strain ATCC 17760/ NCIB 9086 / R18194))
          Length = 649

 Score = 32.7 bits (71), Expect = 8.8
 Identities = 17/50 (34%), Positives = 26/50 (52%), Gaps = 2/50 (4%)
 Frame = +1

Query: 418 QREALPRGSLPPRHLADWLRYSVQHEHERG--DCEPRHTNTGRETGQQGP 561
           +R A   G+L P +   + R+  +++H R   D  PRH N GR    +GP
Sbjct: 115 RRVACEVGALTPPNYRTFCRWKKRYQHSRDVMDVVPRHENKGRREILEGP 164


>UniRef50_Q2SCH6 Cluster: Putative uncharacterized protein; n=2;
           root|Rep: Putative uncharacterized protein - Hahella
           chejuensis (strain KCTC 2396)
          Length = 1383

 Score = 32.7 bits (71), Expect = 8.8
 Identities = 14/29 (48%), Positives = 17/29 (58%)
 Frame = +1

Query: 451 PRHLADWLRYSVQHEHERGDCEPRHTNTG 537
           P+ LADW  + V H+H   DC P H  TG
Sbjct: 30  PQQLADWSGW-VLHDHIDKDCTPAHDGTG 57


>UniRef50_Q22441 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis elegans|Rep: Putative uncharacterized
           protein - Caenorhabditis elegans
          Length = 161

 Score = 32.7 bits (71), Expect = 8.8
 Identities = 12/29 (41%), Positives = 15/29 (51%)
 Frame = -3

Query: 563 PGPCCPVSRPVFVWRGSQSPRSCSCWTEY 477
           P PCC V    +  RG + P+ CSC   Y
Sbjct: 93  PRPCCAVCHDSYASRGPKKPKVCSCLHTY 121


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 671,062,650
Number of Sequences: 1657284
Number of extensions: 13965194
Number of successful extensions: 42509
Number of sequences better than 10.0: 61
Number of HSP's better than 10.0 without gapping: 40819
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 42417
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 54545459628
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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