BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= P5PG0140 (673 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q9PTW9 Cluster: Proteasome subunit alpha type-7; n=24; ... 319 4e-86 UniRef50_Q8TAA3 Cluster: Proteasome subunit alpha type-7-like; n... 304 1e-81 UniRef50_Q27575 Cluster: Proteasome subunit alpha type-7-1B; n=1... 272 5e-72 UniRef50_Q10329 Cluster: Probable proteasome subunit alpha type-... 226 4e-58 UniRef50_Q9NDA2 Cluster: Proteasome subunit alpha type-7; n=13; ... 215 8e-55 UniRef50_UPI0000E49FB5 Cluster: PREDICTED: hypothetical protein;... 205 9e-52 UniRef50_Q7RM37 Cluster: Proteasome subunit alpha type; n=7; Aco... 203 3e-51 UniRef50_Q23TC6 Cluster: Proteasome subunit alpha type 7-like, p... 200 2e-50 UniRef50_Q7QXH1 Cluster: Proteasome subunit alpha type; n=2; Gia... 181 1e-44 UniRef50_UPI0000D9E814 Cluster: PREDICTED: similar to proteasome... 177 2e-43 UniRef50_A2E5C0 Cluster: Family T1, proteasome alpha subunit, th... 171 1e-41 UniRef50_Q60177 Cluster: Proteasome subunit alpha; n=29; Archaea... 165 1e-39 UniRef50_Q4JB24 Cluster: Proteasome subunit alpha; n=6; Thermopr... 164 2e-39 UniRef50_A5BFH7 Cluster: Proteasome subunit alpha type; n=1; Vit... 163 5e-39 UniRef50_Q8ZVM1 Cluster: Proteasome subunit alpha; n=7; Thermopr... 160 2e-38 UniRef50_Q6M0L9 Cluster: Proteasome subunit alpha; n=8; Euryarch... 157 3e-37 UniRef50_Q5V2X8 Cluster: Proteasome subunit alpha 1; n=8; Haloba... 151 1e-35 UniRef50_Q6L0W3 Cluster: Proteasome subunit alpha; n=4; Thermopl... 145 1e-33 UniRef50_Q9YC01 Cluster: Proteasome subunit alpha; n=1; Aeropyru... 143 3e-33 UniRef50_Q74M45 Cluster: NEQ521; n=1; Nanoarchaeum equitans|Rep:... 141 2e-32 UniRef50_P40301 Cluster: Proteasome subunit alpha type-2; n=48; ... 140 4e-32 UniRef50_O81148 Cluster: Proteasome subunit alpha type-4; n=5; M... 139 5e-32 UniRef50_P25787 Cluster: Proteasome subunit alpha type-2; n=54; ... 139 6e-32 UniRef50_A0RWA6 Cluster: 20S proteasome, alpha and beta subunit;... 135 8e-31 UniRef50_A2BKB7 Cluster: Proteasome alpha subunit; n=1; Hyperthe... 135 1e-30 UniRef50_Q017X9 Cluster: Alpha 2 subunit of 20S proteasome; n=6;... 134 2e-30 UniRef50_Q27562 Cluster: Proteasome subunit alpha type-1; n=6; E... 134 2e-30 UniRef50_A2ST52 Cluster: Proteasome alpha subunit; n=1; Methanoc... 133 4e-30 UniRef50_A7D1R0 Cluster: Proteasome endopeptidase complex; n=2; ... 132 7e-30 UniRef50_P23638 Cluster: Proteasome component Y13; n=3; Saccharo... 130 2e-29 UniRef50_Q7QZC5 Cluster: GLP_43_57537_58271; n=3; Giardia intest... 130 3e-29 UniRef50_Q09682 Cluster: Probable proteasome subunit alpha type-... 130 3e-29 UniRef50_Q94561 Cluster: Proteasome subunit alpha type-5; n=2; E... 129 7e-29 UniRef50_Q5CQL5 Cluster: Proteasome subunit alpha type; n=9; Euk... 127 2e-28 UniRef50_P34119 Cluster: Proteasome subunit alpha type-4; n=4; E... 126 4e-28 UniRef50_P34066 Cluster: Proteasome subunit alpha type-1-A; n=4;... 126 6e-28 UniRef50_P25786 Cluster: Proteasome subunit alpha type-1; n=77; ... 123 3e-27 UniRef50_A0CZU2 Cluster: Chromosome undetermined scaffold_32, wh... 121 1e-26 UniRef50_P25789 Cluster: Proteasome subunit alpha type-4; n=113;... 121 1e-26 UniRef50_Q4CKY8 Cluster: Proteasome alpha 2 subunit, putative; n... 121 2e-26 UniRef50_P28066 Cluster: Proteasome subunit alpha type-5; n=115;... 120 3e-26 UniRef50_A2FCM7 Cluster: Proteasome subunit alpha type; n=2; Tri... 120 4e-26 UniRef50_Q5CTQ7 Cluster: Proteasome subunit alpha type; n=3; Cry... 119 6e-26 UniRef50_Q55YJ2 Cluster: Proteasome subunit alpha type; n=3; Bas... 118 1e-25 UniRef50_P52428 Cluster: Proteasome subunit alpha type-1; n=4; O... 118 2e-25 UniRef50_Q2GW78 Cluster: Proteasome subunit alpha type; n=4; Pez... 117 2e-25 UniRef50_A5K435 Cluster: Proteosome subunit alpha type 1, putati... 111 1e-23 UniRef50_O96788 Cluster: Proteasome subunit alpha type-1; n=10; ... 111 1e-23 UniRef50_Q4QFV4 Cluster: Proteasome subunit alpha type; n=7; Try... 110 3e-23 UniRef50_UPI0000E48E53 Cluster: PREDICTED: similar to Proteasome... 109 5e-23 UniRef50_P21242 Cluster: Proteasome component C1; n=18; Eukaryot... 109 6e-23 UniRef50_O81146 Cluster: Proteasome subunit alpha type-6-A; n=15... 107 2e-22 UniRef50_A7AV06 Cluster: Proteasome subunit alpha type 1; n=1; B... 106 4e-22 UniRef50_Q8SRU3 Cluster: 26S PROTEASOME ZETA CHAIN; n=4; Microsp... 106 4e-22 UniRef50_A7AW04 Cluster: Proteasome alpha 5 subunit, putative; n... 106 6e-22 UniRef50_Q4N3Q8 Cluster: Proteasome subunit alpha type 1, putati... 104 2e-21 UniRef50_O23715 Cluster: Proteasome subunit alpha type-3; n=12; ... 103 4e-21 UniRef50_A2E1I9 Cluster: Family T1, proteasome alpha subunit, th... 103 5e-21 UniRef50_Q4P0X9 Cluster: Proteasome subunit alpha type; n=3; Fun... 103 5e-21 UniRef50_Q7QYA1 Cluster: GLP_387_56144_56881; n=2; Giardia intes... 102 7e-21 UniRef50_Q9VK14 Cluster: Proteasome subunit alpha type; n=2; Sop... 101 1e-20 UniRef50_Q6CBM3 Cluster: Yarrowia lipolytica chromosome C of str... 101 1e-20 UniRef50_Q22WB3 Cluster: Proteasome A-type and B-type family pro... 100 4e-20 UniRef50_Q8SRJ0 Cluster: 26S PROTEASOME SUBUNIT ALPHA-4; n=1; En... 100 4e-20 UniRef50_P60900 Cluster: Proteasome subunit alpha type-6; n=69; ... 99 8e-20 UniRef50_UPI0000498A1A Cluster: proteasome alpha subunit; n=2; E... 98 2e-19 UniRef50_A2FJV7 Cluster: Family T1, proteasome alpha subunit, th... 97 3e-19 UniRef50_Q27563 Cluster: Proteasome subunit alpha type-3; n=11; ... 97 3e-19 UniRef50_Q751N3 Cluster: AGL336Wp; n=7; Ascomycota|Rep: AGL336Wp... 96 8e-19 UniRef50_Q0MYX3 Cluster: Proteasome subunit alpha type; n=3; Euk... 95 1e-18 UniRef50_A4UHA5 Cluster: Proteasome subunit alpha type; n=8; Euk... 95 1e-18 UniRef50_Q5CUM6 Cluster: Proteasome subunit alpha type; n=2; Cry... 94 3e-18 UniRef50_A6R382 Cluster: Proteasome component C1; n=3; Pezizomyc... 92 1e-17 UniRef50_Q7QUL1 Cluster: GLP_436_20835_20083; n=2; Giardia intes... 91 2e-17 UniRef50_A0CDQ2 Cluster: Chromosome undetermined scaffold_17, wh... 90 5e-17 UniRef50_A5E6Y2 Cluster: Proteasome component Y7; n=4; Saccharom... 89 9e-17 UniRef50_A4RHU7 Cluster: Proteasome subunit alpha type; n=16; Fu... 86 6e-16 UniRef50_O17586 Cluster: Proteasome subunit alpha type-6; n=9; B... 86 8e-16 UniRef50_Q0CFX9 Cluster: Proteasome subunit alpha type; n=12; Pe... 84 3e-15 UniRef50_A0CF33 Cluster: Chromosome undetermined scaffold_174, w... 84 3e-15 UniRef50_A0NHA5 Cluster: Proteasome subunit alpha type; n=1; Ano... 83 8e-15 UniRef50_UPI0000499E10 Cluster: proteasome alpha subunit; n=1; E... 81 3e-14 UniRef50_Q94II8 Cluster: Proteasome subunit alpha type; n=3; Ory... 80 6e-14 UniRef50_A5K7Q6 Cluster: 20S proteasome alpha subunit G, putativ... 79 1e-13 UniRef50_Q8SR59 Cluster: PROTEASOME ALPHA SUBUNIT C6; n=1; Encep... 78 2e-13 UniRef50_Q9NDA3 Cluster: 20S proteasome alpha 7 subunit; n=1; Tr... 77 4e-13 UniRef50_Q09583 Cluster: Proteasome subunit alpha type-3; n=2; C... 76 7e-13 UniRef50_A4RSN5 Cluster: Proteasome subunit alpha type; n=2; Ost... 76 9e-13 UniRef50_Q7QUP6 Cluster: GLP_47_22543_21776; n=2; Giardia intest... 76 9e-13 UniRef50_Q00ZK2 Cluster: Proteasome subunit alpha type; n=2; Ost... 75 2e-12 UniRef50_Q98RW3 Cluster: Similar to proteasome A-type submit; n=... 75 2e-12 UniRef50_Q8SRU7 Cluster: 26S PROTEASOME ALPHA-TYPE SUBUNIT C9; n... 74 4e-12 UniRef50_UPI000150A654 Cluster: Proteasome A-type and B-type fam... 73 6e-12 UniRef50_Q98S57 Cluster: 26S proteasome SU; n=1; Guillardia thet... 72 1e-11 UniRef50_Q98RV9 Cluster: 26S proteasome SU A5; n=1; Guillardia t... 71 3e-11 UniRef50_Q8SR95 Cluster: 20S PROTEASOME COMPONENT C3; n=1; Encep... 69 8e-11 UniRef50_Q5CUM9 Cluster: Proteasome subunit alpha1; n=3; Cryptos... 68 2e-10 UniRef50_Q7QSC8 Cluster: GLP_105_6759_5881; n=2; Giardia intesti... 65 2e-09 UniRef50_Q9YER0 Cluster: Proteasome beta subunit; n=1; Aeropyrum... 64 4e-09 UniRef50_Q4N061 Cluster: Proteasome subunit alpha type 3, putati... 62 2e-08 UniRef50_Q8TW10 Cluster: Protease subunit of the proteasome; n=2... 60 6e-08 UniRef50_Q7QW44 Cluster: GLP_457_25625_26368; n=2; Giardia intes... 59 8e-08 UniRef50_A3DN21 Cluster: 20S proteasome, A and B subunits; n=1; ... 59 8e-08 UniRef50_Q9YES4 Cluster: Proteasome beta subunit; n=1; Aeropyrum... 59 1e-07 UniRef50_Q3TEL1 Cluster: 2 days neonate thymus thymic cells cDNA... 58 1e-07 UniRef50_A2D8G5 Cluster: Family T1, proteasome alpha subunit, th... 58 2e-07 UniRef50_Q4U9U5 Cluster: Proteasome subunit alpha type; n=3; Pir... 58 3e-07 UniRef50_Q9GU37 Cluster: Proteasome subunit alpha type-1; n=8; T... 58 3e-07 UniRef50_Q8ZST5 Cluster: Proteasome, beta subunit; n=5; Thermopr... 57 4e-07 UniRef50_A2BN24 Cluster: Proteasome beta subunit; n=2; Desulfuro... 56 8e-07 UniRef50_Q9P996 Cluster: Proteasome subunit beta precursor; n=10... 56 1e-06 UniRef50_A0RXV1 Cluster: 20S proteasome, alpha and beta subunit;... 55 1e-06 UniRef50_Q58634 Cluster: Proteasome subunit beta precursor; n=9;... 55 2e-06 UniRef50_Q98S33 Cluster: 26S proteasome SU alpha7; n=1; Guillard... 54 2e-06 UniRef50_A7DQ84 Cluster: Proteasome endopeptidase complex; n=1; ... 54 2e-06 UniRef50_A2F568 Cluster: Family T1, proteasome alpha subunit, th... 53 5e-06 UniRef50_P28061 Cluster: Proteasome subunit beta precursor; n=4;... 50 5e-05 UniRef50_Q5KFP2 Cluster: Proteasome subunit beta type; n=3; Fung... 48 2e-04 UniRef50_A7SI53 Cluster: Predicted protein; n=1; Nematostella ve... 47 4e-04 UniRef50_Q8SQP9 Cluster: PROTEASOME REGULATORY SUBUNIT 8; n=1; E... 47 4e-04 UniRef50_P22141 Cluster: Proteasome component C11; n=36; Ascomyc... 47 4e-04 UniRef50_O23370 Cluster: Cell wall protein like; n=15; Magnoliop... 46 6e-04 UniRef50_Q8ZYF2 Cluster: Proteasome beta subunit; n=5; Thermopro... 46 8e-04 UniRef50_A2BN27 Cluster: Proteasome beta; n=3; Desulfurococcales... 46 0.001 UniRef50_Q8IAR3 Cluster: Proteasome subunit alpha, putative; n=5... 44 0.003 UniRef50_UPI0000499449 Cluster: proteasome beta subunit; n=1; En... 44 0.004 UniRef50_Q98RN2 Cluster: 26s proteasome SU A6; n=1; Guillardia t... 44 0.004 UniRef50_A1RX71 Cluster: Proteasome endopeptidase complex; n=1; ... 43 0.006 UniRef50_Q9UXF3 Cluster: Proteasome subunit beta precursor; n=5;... 43 0.006 UniRef50_A6R393 Cluster: Proteasome component C5; n=5; Ascomycot... 43 0.008 UniRef50_Q23FB2 Cluster: Proteasome, putative; n=5; Oligohymenop... 42 0.018 UniRef50_Q8T8V8 Cluster: Proteasome subunit beta type; n=13; Neo... 41 0.024 UniRef50_A2DD57 Cluster: Proteasome subunit beta type; n=1; Tric... 41 0.024 UniRef50_Q966I8 Cluster: Proteasome subunit beta type; n=2; Caen... 41 0.031 UniRef50_P23724 Cluster: Proteasome component C5; n=23; Fungi/Me... 40 0.041 UniRef50_Q6CA23 Cluster: Yarrowia lipolytica chromosome D of str... 39 0.096 UniRef50_A2F8W4 Cluster: Family T1, proteasome beta subunit, thr... 37 0.51 UniRef50_P40306 Cluster: Proteasome subunit beta type-10 precurs... 37 0.51 UniRef50_UPI000023D2A5 Cluster: hypothetical protein FG06803.1; ... 36 0.67 UniRef50_Q1YM98 Cluster: Putative uncharacterized protein; n=1; ... 36 0.89 UniRef50_O24079 Cluster: Proteasome subunit; n=1; Medicago sativ... 35 1.6 UniRef50_Q0UWV2 Cluster: Predicted protein; n=4; Pezizomycotina|... 35 1.6 UniRef50_Q9VNA5 Cluster: Probable proteasome subunit beta type-4... 35 1.6 UniRef50_A2DSN0 Cluster: Cellulosomal scaffoldin anchoring prote... 34 3.6 UniRef50_O23717 Cluster: Proteasome subunit beta type-5-A precur... 34 3.6 UniRef50_Q00826 Cluster: Probable proteasome subunit beta type-2... 34 3.6 UniRef50_Q0HJB8 Cluster: Exodeoxyribonuclease V, gamma subunit; ... 33 4.8 UniRef50_A4RRA7 Cluster: Proteasome subunit beta type; n=2; Ostr... 33 4.8 UniRef50_Q2J9Q3 Cluster: 20S proteasome, A and B subunits; n=23;... 33 6.3 UniRef50_Q7QXH2 Cluster: GLP_14_13300_13022; n=1; Giardia lambli... 33 6.3 UniRef50_Q5CU00 Cluster: Pre3p/proteasome regulatory subunit bet... 33 6.3 UniRef50_A0CW62 Cluster: Proteasome subunit beta type; n=3; Olig... 33 6.3 UniRef50_A0P0V6 Cluster: Putative uncharacterized protein; n=2; ... 33 8.3 UniRef50_Q9XG34 Cluster: 26S proteasome IOTA SU; n=1; Guillardia... 33 8.3 UniRef50_Q8T915 Cluster: AT05866p; n=1; Drosophila melanogaster|... 33 8.3 UniRef50_Q8T8U1 Cluster: Proteasome subunit beta type; n=1; Dros... 33 8.3 UniRef50_Q22MS9 Cluster: Proteasome subunit beta type; n=2; Olig... 33 8.3 UniRef50_Q59F72 Cluster: Proteasome alpha 6 subunit variant; n=1... 33 8.3 UniRef50_Q5A9K1 Cluster: Possible intermediate filament protein ... 33 8.3 >UniRef50_Q9PTW9 Cluster: Proteasome subunit alpha type-7; n=24; Bilateria|Rep: Proteasome subunit alpha type-7 - Carassius auratus (Goldfish) Length = 251 Score = 319 bits (783), Expect = 4e-86 Identities = 152/197 (77%), Positives = 171/197 (86%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 AITVFSPDGHL QVEYAQEAV+KGSTA EKKSVAKLQEERTVRKIC L Sbjct: 8 AITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGKDIVVLGVEKKSVAKLQEERTVRKICAL 67 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 D+HV MAFAGLTADARI+INRA++ECQSH+LTVEDPVT+EYITRYIA LKQ+YTQSNGRR Sbjct: 68 DEHVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIATLKQRYTQSNGRR 127 Query: 441 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATEN 620 PFGIS LI GFD+DG+P L+QT+PSG Y+ WKANA GRSAKTVREFLEKNYT + +A++N Sbjct: 128 PFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTDEAIASDN 187 Query: 621 GAVKLAIRALLEVVQSG 671 A+KLAI+ALLEVVQSG Sbjct: 188 DAIKLAIKALLEVVQSG 204 >UniRef50_Q8TAA3 Cluster: Proteasome subunit alpha type-7-like; n=116; Eukaryota|Rep: Proteasome subunit alpha type-7-like - Homo sapiens (Human) Length = 256 Score = 304 bits (746), Expect = 1e-81 Identities = 151/203 (74%), Positives = 168/203 (82%), Gaps = 6/203 (2%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 AITVFSPDGHL QVEYAQEAV+KGSTA EKKSVAKLQ+ERTVRKIC L Sbjct: 8 AITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGTNIVVLGVEKKSVAKLQDERTVRKICAL 67 Query: 261 DDHVVMAFA------GLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYT 422 DDHV MAFA GLTADAR++INRA++ECQSHKLTVEDPVT+EYITR+IA LKQKYT Sbjct: 68 DDHVCMAFAVLTIFIGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYT 127 Query: 423 QSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTAD 602 QSNGRRPFGIS LI GFD DG L+QT+PSG Y+ WKANA GRSAKTVREFLEKNYT D Sbjct: 128 QSNGRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTED 187 Query: 603 EVATENGAVKLAIRALLEVVQSG 671 +A+++ A+KLAI+ALLEVVQSG Sbjct: 188 AIASDSEAIKLAIKALLEVVQSG 210 >UniRef50_Q27575 Cluster: Proteasome subunit alpha type-7-1B; n=16; Drosophila|Rep: Proteasome subunit alpha type-7-1B - Drosophila melanogaster (Fruit fly) Length = 252 Score = 272 bits (667), Expect = 5e-72 Identities = 128/196 (65%), Positives = 156/196 (79%), Gaps = 3/196 (1%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 A+T++SPDGHLLQVEYAQEAVR+GST EK+SV LQEER VRKIC+L Sbjct: 8 AVTIYSPDGHLLQVEYAQEAVRRGSTVMGLRTNNAIVIGVEKRSVGDLQEERMVRKICML 67 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 DDHVVM F+GLTADARIL++RAQ+E QSH+L E P T+EYITRYIA LKQ YTQSNGRR Sbjct: 68 DDHVVMTFSGLTADARILVSRAQMEAQSHRLNFEKPTTVEYITRYIAQLKQNYTQSNGRR 127 Query: 441 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVAT-- 614 PFG+SCL+GGFD DG+PHLFQT+PSGI+YEW+AN TGRS++ VR+++EK+ ADE+ T Sbjct: 128 PFGLSCLVGGFDEDGTPHLFQTDPSGIFYEWRANTTGRSSQPVRDYMEKH--ADEILTIA 185 Query: 615 -ENGAVKLAIRALLEV 659 E A+K +R L+ V Sbjct: 186 DEAAAIKHIVRTLVSV 201 >UniRef50_Q10329 Cluster: Probable proteasome subunit alpha type-7; n=3; Ascomycota|Rep: Probable proteasome subunit alpha type-7 - Schizosaccharomyces pombe (Fission yeast) Length = 259 Score = 226 bits (552), Expect = 4e-58 Identities = 108/197 (54%), Positives = 146/197 (74%), Gaps = 1/197 (0%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 A++VFSPDG LLQVEY QEAVR+G+TA E+K+V KLQ +KI ++ Sbjct: 7 ALSVFSPDGRLLQVEYGQEAVRRGTTAIALRGNECIVIGVERKNVPKLQNVSNFQKIAMV 66 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 D+HV +AFAGL ADARILI++A++E Q+HKL + DPV++EY+TRY+AG++QKYTQS G R Sbjct: 67 DNHVCLAFAGLNADARILIDKARVEAQNHKLNLADPVSIEYLTRYVAGVQQKYTQSGGVR 126 Query: 441 PFGISCLIGGFDY-DGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATE 617 PFG+S LI GFD D +P ++QTEP+GIY WKA A GR++K RE+LEKN+ E + Sbjct: 127 PFGVSTLIAGFDVGDNTPRVYQTEPAGIYNAWKATAIGRASKAAREYLEKNW--KEGLSR 184 Query: 618 NGAVKLAIRALLEVVQS 668 + + LA+ +LLEVVQ+ Sbjct: 185 DETIHLAVSSLLEVVQT 201 >UniRef50_Q9NDA2 Cluster: Proteasome subunit alpha type-7; n=13; Eukaryota|Rep: Proteasome subunit alpha type-7 - Trypanosoma brucei brucei Length = 247 Score = 215 bits (525), Expect = 8e-55 Identities = 105/197 (53%), Positives = 138/197 (70%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 AITVFSPDGHL QVEYAQEAVRKG A EKKSV KLQ+ RT RKI L Sbjct: 6 AITVFSPDGHLFQVEYAQEAVRKGLCAVGVKGKDSIIFAVEKKSVQKLQDSRTTRKIYKL 65 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 D+H+ +A AGL+ADAR+++N AQ+ECQ +L+ ED + ++ + RY+A ++Q+ TQS+G R Sbjct: 66 DEHIYLASAGLSADARVVVNHAQLECQRFRLSYEDAIDVDLLVRYVARVQQRSTQSSGSR 125 Query: 441 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATEN 620 P+G+S +IGGF+ +G P L++TEPSG W A A GR+ K V EF+EKNY + T + Sbjct: 126 PYGVSTIIGGFNENGQPQLWKTEPSGTSSAWNAAAIGRNDKVVLEFMEKNY--QDGMTRD 183 Query: 621 GAVKLAIRALLEVVQSG 671 V AI+ALLE V+SG Sbjct: 184 RCVHFAIKALLEAVESG 200 >UniRef50_UPI0000E49FB5 Cluster: PREDICTED: hypothetical protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 266 Score = 205 bits (500), Expect = 9e-52 Identities = 93/112 (83%), Positives = 105/112 (93%) Frame = +3 Query: 201 EKKSVAKLQEERTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLE 380 EKKSVAKLQEERTVRKIC+LDDHV MAFAGLTADARILINRA+IECQSH+LTVEDPVT+E Sbjct: 19 EKKSVAKLQEERTVRKICVLDDHVCMAFAGLTADARILINRARIECQSHRLTVEDPVTVE 78 Query: 381 YITRYIAGLKQKYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWK 536 YITR++A LKQ+YTQSNGRRPFG+S LI GFDYDGSP L+QT+P+G Y+ WK Sbjct: 79 YITRFMAQLKQRYTQSNGRRPFGLSTLIVGFDYDGSPRLYQTDPAGTYHSWK 130 Score = 139 bits (336), Expect = 6e-32 Identities = 63/87 (72%), Positives = 76/87 (87%) Frame = +3 Query: 411 QKYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKN 590 ++YTQSNGRRPFG+S LI GFDYDGSP L+QT+P+G Y+ WKANA GRSAKTVREFLEK+ Sbjct: 130 KRYTQSNGRRPFGLSTLIVGFDYDGSPRLYQTDPAGTYHSWKANAIGRSAKTVREFLEKH 189 Query: 591 YTADEVATENGAVKLAIRALLEVVQSG 671 Y+ + V +E+ VKLA+RALLEVVQSG Sbjct: 190 YSDEVVESESETVKLAVRALLEVVQSG 216 >UniRef50_Q7RM37 Cluster: Proteasome subunit alpha type; n=7; Aconoidasida|Rep: Proteasome subunit alpha type - Plasmodium yoelii yoelii Length = 278 Score = 203 bits (496), Expect = 3e-51 Identities = 98/195 (50%), Positives = 133/195 (68%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 AITVFSPDGHLLQVE+A EAV+KG A EKK++ KLQ RT K+ L Sbjct: 43 AITVFSPDGHLLQVEHALEAVKKGGCAVAIKSSNFAVLAVEKKNIPKLQNPRTTEKLVKL 102 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 D+H +AF+GL ADARIL+N+ ++ECQ + L ++ P ++YI +Y+A ++QK+T G R Sbjct: 103 DEHTCLAFSGLNADARILVNKTRLECQRYYLNMDQPAPVDYIAKYVARIQQKFTHRGGVR 162 Query: 441 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATEN 620 PFGI+ LI GF + ++QTEPSGIY WKA A G++AK V+EFLEKNY E +N Sbjct: 163 PFGIATLITGFKNNKEICIYQTEPSGIYASWKAQAIGKNAKVVQEFLEKNY--QENMEKN 220 Query: 621 GAVKLAIRALLEVVQ 665 + LA++A+ EVV+ Sbjct: 221 ECLLLALKAIFEVVE 235 >UniRef50_Q23TC6 Cluster: Proteasome subunit alpha type 7-like, putative; n=5; Oligohymenophorea|Rep: Proteasome subunit alpha type 7-like, putative - Tetrahymena thermophila SB210 Length = 242 Score = 200 bits (489), Expect = 2e-50 Identities = 104/197 (52%), Positives = 126/197 (63%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 AITVF G+L QVEYA AV +G + EK LQE RT+RK+ L Sbjct: 6 AITVFGKIGNLFQVEYAMAAVNQGLCSIGIRGTDCIVMGVEKNPTTILQETRTIRKVQRL 65 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 DD + ++GLT DARIL N A++ECQS+ L +D V + YI RYIA ++QKYTQ +G R Sbjct: 66 DDATCICYSGLTPDARILTNIAKVECQSYSLNYDDRVPINYIARYIASVQQKYTQKSGAR 125 Query: 441 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATEN 620 PFGIS L+GGFD G P LFQT+PSG EWKA A G+ KTV E LEKNY +E E Sbjct: 126 PFGISTLVGGFDSKGQPRLFQTDPSGACTEWKAVALGKHRKTVMENLEKNY-QEEYLAEE 184 Query: 621 GAVKLAIRALLEVVQSG 671 ++LA R LLEVVQSG Sbjct: 185 KCLELACRVLLEVVQSG 201 >UniRef50_Q7QXH1 Cluster: Proteasome subunit alpha type; n=2; Giardia intestinalis|Rep: Proteasome subunit alpha type - Giardia lamblia ATCC 50803 Length = 214 Score = 181 bits (441), Expect = 1e-44 Identities = 86/194 (44%), Positives = 127/194 (65%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 ++TVFSPDGHL+QVE+A +AV +G++A E+K A+LQ+ R +KI + Sbjct: 8 SLTVFSPDGHLIQVEHAHKAVERGTSAVAVRSAAGIVLAIERKQTARLQDPRASQKIFDV 67 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 DDH++ FAGLTADAR+LI+RA++ECQ++++T + ++E I + +A + Q +T G R Sbjct: 68 DDHIIATFAGLTADARVLIDRARLECQAYRMTYDVAPSVEIIAKAVASILQSHTHRGGTR 127 Query: 441 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATEN 620 PFG+S ++ G D +GS H+F +PSG+Y EWKA A G T+ EFLEK E N Sbjct: 128 PFGVSIILAGNDLNGS-HVFMCDPSGVYTEWKALAIGNQCVTIIEFLEKKLKEGEPQNTN 186 Query: 621 GAVKLAIRALLEVV 662 A+ LA AL E++ Sbjct: 187 DALSLAKAALSELI 200 >UniRef50_UPI0000D9E814 Cluster: PREDICTED: similar to proteasome (prosome, macropain) subunit, alpha type, 8 isoform 2; n=1; Macaca mulatta|Rep: PREDICTED: similar to proteasome (prosome, macropain) subunit, alpha type, 8 isoform 2 - Macaca mulatta Length = 261 Score = 177 bits (431), Expect = 2e-43 Identities = 86/111 (77%), Positives = 94/111 (84%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 AITVFSPDGHL QVEYAQEAV+KGSTA EKKSVAKLQ+ERTVRKIC L Sbjct: 8 AITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGTNIVVLGVEKKSVAKLQDERTVRKICAL 67 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQ 413 DDHV MAFAGLTADAR++INRA++ECQSHKLTVEDPVT+EYITR+IA LKQ Sbjct: 68 DDHVCMAFAGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQ 118 >UniRef50_A2E5C0 Cluster: Family T1, proteasome alpha subunit, threonine peptidase; n=2; Trichomonas vaginalis G3|Rep: Family T1, proteasome alpha subunit, threonine peptidase - Trichomonas vaginalis G3 Length = 238 Score = 171 bits (416), Expect = 1e-41 Identities = 84/193 (43%), Positives = 119/193 (61%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 A+T FS DG L Q+EYA A G+T EK+ + KLQ++ + +CLL Sbjct: 6 ALTRFSSDGRLFQIEYAAAAAHNGTTVLAIQAPGIIVAAIEKRDMMKLQKQDSSNNMCLL 65 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 D H++ AF GL ADAR+L+ +AQ E QS++LT ED + +E I RYIA ++ YTQS G R Sbjct: 66 DKHILCAFTGLPADARVLVEKAQFEAQSYRLTFEDAIPIENIARYIATVQLTYTQSGGVR 125 Query: 441 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATEN 620 PFG++ LI GFD PH+++T PSGI EWKA GR V+E++EK Y + +E+ Sbjct: 126 PFGVTTLICGFDPLDKPHIYETLPSGILSEWKARGIGRFGHPVQEYIEKYYV--DNLSED 183 Query: 621 GAVKLAIRALLEV 659 ++ I +L E+ Sbjct: 184 DVKRITIGSLREI 196 >UniRef50_Q60177 Cluster: Proteasome subunit alpha; n=29; Archaea|Rep: Proteasome subunit alpha - Methanococcus jannaschii Length = 261 Score = 165 bits (400), Expect = 1e-39 Identities = 86/190 (45%), Positives = 121/190 (63%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 AITVFSP+G L QVEYA+EAVR+G+TA +++ +KL + R++ KI + Sbjct: 12 AITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIEKIFQI 71 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 DDHV A +GL ADAR+LI+RA++E Q ++LT + +++E + + I +KQ YTQ G R Sbjct: 72 DDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVR 131 Query: 441 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATEN 620 PFG+S LI G D LF+T+PSG E+KA A G V E LEK Y D++ + Sbjct: 132 PFGVSLLIAGID-KNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKEY-RDDITLDE 189 Query: 621 GAVKLAIRAL 650 G ++LAI AL Sbjct: 190 G-LELAITAL 198 >UniRef50_Q4JB24 Cluster: Proteasome subunit alpha; n=6; Thermoprotei|Rep: Proteasome subunit alpha - Sulfolobus acidocaldarius Length = 242 Score = 164 bits (399), Expect = 2e-39 Identities = 82/197 (41%), Positives = 118/197 (59%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 AIT+FSPDG L QV+YA EAV++G T EK+ +L + + KI +L Sbjct: 13 AITIFSPDGSLYQVDYAFEAVKRGWTTLGVKTKSGVVLLAEKRKATQLLDVDGIEKIFML 72 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 DDHV FAGL +D RILI+ A+ + H+L ++P+++EY+T+ I+ +KQ YTQ G R Sbjct: 73 DDHVGCTFAGLASDGRILIDYARSQALQHRLIYDEPISIEYLTKVISDVKQAYTQHGGVR 132 Query: 441 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATEN 620 PFG++ ++GG D P L TEPSG + + A A G+ T E+LEKNY D Sbjct: 133 PFGVALIVGGIDKGKQPKLLMTEPSGQFMPYYAVAIGQGGYTATEYLEKNYKED--LDIQ 190 Query: 621 GAVKLAIRALLEVVQSG 671 + LA+RAL+ ++ G Sbjct: 191 STILLALRALMATLKPG 207 >UniRef50_A5BFH7 Cluster: Proteasome subunit alpha type; n=1; Vitis vinifera|Rep: Proteasome subunit alpha type - Vitis vinifera (Grape) Length = 219 Score = 163 bits (395), Expect = 5e-39 Identities = 80/112 (71%), Positives = 89/112 (79%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 AITVFSPDGHL QVEYA EAVRKG+ A EKKS AKLQ+ RTVRKI L Sbjct: 7 AITVFSPDGHLFQVEYALEAVRKGNAAVGVRGTDTIVLGVEKKSTAKLQDSRTVRKIVNL 66 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQK 416 DDH+ +A AGL ADAR+LINRA+IECQSH+LTVEDPVT+EYITRYIAGL+QK Sbjct: 67 DDHIALACAGLKADARVLINRARIECQSHRLTVEDPVTVEYITRYIAGLQQK 118 Score = 39.1 bits (87), Expect = 0.096 Identities = 23/34 (67%), Positives = 26/34 (76%) Frame = +3 Query: 570 REFLEKNYTADEVATENGAVKLAIRALLEVVQSG 671 REFLEKNY E + + VKLAIRALLEVV+SG Sbjct: 141 REFLEKNYK--ETSGQE-TVKLAIRALLEVVESG 171 >UniRef50_Q8ZVM1 Cluster: Proteasome subunit alpha; n=7; Thermoprotei|Rep: Proteasome subunit alpha - Pyrobaculum aerophilum Length = 243 Score = 160 bits (389), Expect = 2e-38 Identities = 81/195 (41%), Positives = 122/195 (62%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 AIT+FSP+G + QVEYA EAV++G EK+ ++ L + ++ KI L+ Sbjct: 12 AITIFSPEGKIYQVEYAGEAVKRGWPTVGVKCKAGVVLTAEKRKISALFDSSSLEKIYLI 71 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 D+HV + +GL ADARILI+ A+ SH+ ++P+ +E++T+ + LKQ+YTQ G R Sbjct: 72 DEHVAASPSGLLADARILIDYARDVALSHRFIYDEPIDVEFLTKAVCNLKQQYTQFGGAR 131 Query: 441 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATEN 620 PFG++ LI G D G+ L+QT+PSG+Y + A A G + T+ EFLEKNY D E Sbjct: 132 PFGVALLIAGVDRHGA-RLYQTDPSGVYIGYFATAIGAESGTITEFLEKNYKFDMEMGE- 189 Query: 621 GAVKLAIRALLEVVQ 665 ++LA++AL V+ Sbjct: 190 -CIELALKALASAVE 203 >UniRef50_Q6M0L9 Cluster: Proteasome subunit alpha; n=8; Euryarchaeota|Rep: Proteasome subunit alpha - Methanococcus maripaludis Length = 259 Score = 157 bits (380), Expect = 3e-37 Identities = 82/195 (42%), Positives = 121/195 (62%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 AIT+FSP+G L QVEYA+EAVR+G+TA +++ +KL + ++ KI + Sbjct: 13 AITIFSPEGRLYQVEYAREAVRRGTTAVGIKCKDGVVLAVDRRITSKLIDVSSIEKIFQI 72 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 DDH+V A +GL ADAR+LI+RA+IE Q ++++ + +T+E + + I +KQ YTQ G R Sbjct: 73 DDHIVAATSGLVADARVLIDRARIEAQMNRVSYGEAITVEALAKKICDIKQAYTQHGGAR 132 Query: 441 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATEN 620 PFG++ LI G D S LF+T+PSG E+KA A G E LE Y DE T + Sbjct: 133 PFGLALLITGIDRH-SARLFETDPSGALIEYKATAIGSGRPIAMEVLESKY--DENMTVS 189 Query: 621 GAVKLAIRALLEVVQ 665 ++LA+ AL + + Sbjct: 190 EGMELALYALSKTTE 204 >UniRef50_Q5V2X8 Cluster: Proteasome subunit alpha 1; n=8; Halobacteriaceae|Rep: Proteasome subunit alpha 1 - Haloarcula marismortui (Halobacterium marismortui) Length = 260 Score = 151 bits (366), Expect = 1e-35 Identities = 82/192 (42%), Positives = 117/192 (60%) Frame = +3 Query: 84 ITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLD 263 IT+FSPDG L QVEYA+EAV++G+ + +K+ + L E +V KI D Sbjct: 14 ITIFSPDGRLYQVEYAREAVKRGTASIGVRTSDGVVLAVDKRIRSPLMERSSVEKIHKAD 73 Query: 264 DHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRP 443 DH+ +A AG ADAR LI+ A+ + Q ++L +PV +E +T+ I Q+YTQ G RP Sbjct: 74 DHIGIASAGHVADARQLIDFARRQAQVNQLRYGEPVGVETLTKEITDYIQQYTQVGGARP 133 Query: 444 FGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENG 623 FG++ +IGG +G P LF+T+PSG YEWKA A G +R++LE++Y DE + Sbjct: 134 FGVALIIGGI-VNGEPRLFETDPSGTPYEWKALAVGADRGDIRDYLEEHY--DEGMDLDE 190 Query: 624 AVKLAIRALLEV 659 V LA+ AL V Sbjct: 191 GVDLALAALASV 202 >UniRef50_Q6L0W3 Cluster: Proteasome subunit alpha; n=4; Thermoplasmatales|Rep: Proteasome subunit alpha - Picrophilus torridus Length = 234 Score = 145 bits (351), Expect = 1e-33 Identities = 81/194 (41%), Positives = 113/194 (58%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 AITVFSPDG L QVEYA+EAV+KGSTA EKK ++L E+ ++ KI L+ Sbjct: 11 AITVFSPDGRLFQVEYAREAVKKGSTALGIKFKDGVALISEKKVRSRLVEKTSLEKIQLI 70 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 DD V +GL ADAR+LI+ A+I Q K+T + +E + + +A Q+YTQ G R Sbjct: 71 DDRVAAVTSGLVADARVLIDFARISDQQEKVTYGSLMNIENLVKRVADQMQQYTQYGGVR 130 Query: 441 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATEN 620 P+G+S + G D G P LF +P+G E+K + G V +LEK Y E +E+ Sbjct: 131 PYGVSIIFAGLDSIG-PRLFDCDPAGTINEYKCVSIGAGKDQVTAYLEKEY--KENLSED 187 Query: 621 GAVKLAIRALLEVV 662 A+++ I AL V Sbjct: 188 EAIRMGIAALKSAV 201 >UniRef50_Q9YC01 Cluster: Proteasome subunit alpha; n=1; Aeropyrum pernix|Rep: Proteasome subunit alpha - Aeropyrum pernix Length = 258 Score = 143 bits (347), Expect = 3e-33 Identities = 72/195 (36%), Positives = 113/195 (57%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 A T+FSP+G L QV YA EAV+KG T+ EK+ + L + + KI + Sbjct: 15 AATIFSPEGDLYQVRYAFEAVKKGWTSLGIKTNEGVVIAAEKRFIGPLVDIDDIDKIYKI 74 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 DDH+ +AFAG+ D RILI+ A++ H+L +P +E + + +A +KQ YTQ G R Sbjct: 75 DDHIGVAFAGMGGDGRILIDYARVFTVRHRLLYGEPPPVELVAKVVADVKQAYTQHGGVR 134 Query: 441 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATEN 620 PFG++ + G + DG+ +++T+P G Y+ +KA A G + E EK+Y +D E Sbjct: 135 PFGVALIFAGVNPDGTTKVYRTDPGGQYFSFKAIAIGSGEQVANEMFEKHYRSDMSLEE- 193 Query: 621 GAVKLAIRALLEVVQ 665 A KLA++ L +++ Sbjct: 194 -ATKLALKILYAIIR 207 >UniRef50_Q74M45 Cluster: NEQ521; n=1; Nanoarchaeum equitans|Rep: NEQ521 - Nanoarchaeum equitans Length = 250 Score = 141 bits (341), Expect = 2e-32 Identities = 72/190 (37%), Positives = 111/190 (58%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 A T+FSPDG LLQVEYA+ V++ TA +KK V K ++ K+ ++ Sbjct: 15 ASTLFSPDGRLLQVEYARTTVKQSPTAIGMLYKTGVLVIGDKKIVEKFVIPSSIEKVYIV 74 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 DDHV+ A AG+ D R+LI RA++ Q++K P+ + + + IA +KQ+YTQ G R Sbjct: 75 DDHVIAAPAGIIGDGRVLIERARVIAQTYKYFYGHPIDIRGLVKEIADIKQEYTQIGGVR 134 Query: 441 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATEN 620 PFG+S + G D D H+F TEP G+++E+K G + V ++L K Y +E + Sbjct: 135 PFGVSIIFAGID-DTGKHIFVTEPGGMFWEYKLAVIGEGEQKVLDYLGKEY--NENLSLK 191 Query: 621 GAVKLAIRAL 650 A++L ++AL Sbjct: 192 KAIELGLKAL 201 >UniRef50_P40301 Cluster: Proteasome subunit alpha type-2; n=48; Eukaryota|Rep: Proteasome subunit alpha type-2 - Drosophila melanogaster (Fruit fly) Length = 234 Score = 140 bits (338), Expect = 4e-32 Identities = 72/192 (37%), Positives = 116/192 (60%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 ++T FSP G L+Q+EYA AV G+ + E K + L E+ +V ++ ++ Sbjct: 9 SLTTFSPSGKLVQLEYALAAVSGGAPSVGIIASNGVVIATENKHKSPLYEQHSVHRVEMI 68 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 +H+ M ++G+ D R+L+ +A+ Q++ LT ++P+ + + + +A L Q+YTQS G R Sbjct: 69 YNHIGMVYSGMGPDYRLLVKQARKIAQTYYLTYKEPIPVSQLVQRVATLMQEYTQSGGVR 128 Query: 441 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATEN 620 PFG+S LI G+D D P+L+Q++PSG Y+ WKA A G++A + FLEK Y+ D + Sbjct: 129 PFGVSLLICGWDND-RPYLYQSDPSGAYFAWKATAMGKNAVNGKTFLEKRYSED--LELD 185 Query: 621 GAVKLAIRALLE 656 AV AI L E Sbjct: 186 DAVHTAILTLKE 197 >UniRef50_O81148 Cluster: Proteasome subunit alpha type-4; n=5; Magnoliophyta|Rep: Proteasome subunit alpha type-4 - Arabidopsis thaliana (Mouse-ear cress) Length = 250 Score = 139 bits (337), Expect = 5e-32 Identities = 73/195 (37%), Positives = 110/195 (56%), Gaps = 1/195 (0%) Frame = +3 Query: 87 TVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKL-QEERTVRKICLLD 263 T+FSP+G L QVEYA EA+ +A EKK +KL Q + K+ +D Sbjct: 10 TIFSPEGRLYQVEYAMEAIGNAGSAIGILSKDGVVLIGEKKVTSKLLQTSTSAEKMYKID 69 Query: 264 DHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRP 443 DHV A AG+ +DA ILIN A+++ Q + ++P+ +E + + + KQ YTQ G RP Sbjct: 70 DHVACAVAGIMSDANILINTARVQAQRYTFMYQEPMPVEQLVQSLCDTKQGYTQFGGLRP 129 Query: 444 FGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENG 623 FG+S L G+D L+ ++PSG Y WKA A G + + + L+++Y D AT Sbjct: 130 FGVSFLFAGWDKHHGFQLYMSDPSGNYGGWKAAAVGANNQAAQSILKQDYKDD--ATREE 187 Query: 624 AVKLAIRALLEVVQS 668 AV+LA++ L + + S Sbjct: 188 AVELALKVLTKTMDS 202 >UniRef50_P25787 Cluster: Proteasome subunit alpha type-2; n=54; Eukaryota|Rep: Proteasome subunit alpha type-2 - Homo sapiens (Human) Length = 234 Score = 139 bits (336), Expect = 6e-32 Identities = 72/192 (37%), Positives = 115/192 (59%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 ++T FSP G L+Q+EYA AV G+ + EKK + L +ER+V K+ + Sbjct: 9 SLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDERSVHKVEPI 68 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 H+ + ++G+ D R+L++RA+ Q + L ++P+ + + +A + Q+YTQS G R Sbjct: 69 TKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQSGGVR 128 Query: 441 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATEN 620 PFG+S LI G++ +G P+LFQ++PSG Y+ WKA A G++ + FLEK Y D + E+ Sbjct: 129 PFGVSLLICGWN-EGRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNED-LELED 186 Query: 621 GAVKLAIRALLE 656 A+ AI L E Sbjct: 187 -AIHTAILTLKE 197 >UniRef50_A0RWA6 Cluster: 20S proteasome, alpha and beta subunit; n=4; Thermoprotei|Rep: 20S proteasome, alpha and beta subunit - Cenarchaeum symbiosum Length = 245 Score = 135 bits (327), Expect = 8e-31 Identities = 72/171 (42%), Positives = 103/171 (60%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 AITVFSPDG L QVEYA E VR+G+ A E+K +LQ T++KI + Sbjct: 11 AITVFSPDGRLYQVEYAIETVRRGTIAVGVKSTGGIVIAVEEKP-RRLQISDTIQKIFQV 69 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 DDH+ +A AG DAR + A+ QS+++ ++ V +E + +++A Q++TQ G R Sbjct: 70 DDHLGVAAAGYIPDARSQVENARFFSQSNRMMYDESVEVEAVAKHLADQCQQFTQYAGVR 129 Query: 441 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 593 PFG++ +IGG D G LF T+PSG Y + A A G ++ V EFLEK+Y Sbjct: 130 PFGVALIIGGVDDGGKGQLFLTDPSGTYISYDAIAIGAGSEQVTEFLEKSY 180 >UniRef50_A2BKB7 Cluster: Proteasome alpha subunit; n=1; Hyperthermus butylicus DSM 5456|Rep: Proteasome alpha subunit - Hyperthermus butylicus (strain DSM 5456 / JCM 9403) Length = 243 Score = 135 bits (326), Expect = 1e-30 Identities = 73/192 (38%), Positives = 106/192 (55%) Frame = +3 Query: 90 VFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDDH 269 +FSPDG L QVEYA EA ++G T EKK + L + + K+ ++D+H Sbjct: 18 MFSPDGRLFQVEYAMEAAKRGWTMVGVRARDGVVIVAEKKKTSPLIDIEQLEKVYMVDEH 77 Query: 270 VVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFG 449 + F G +D R+LI+ A+ +K + + +EY+TR I L Q YTQ G RPFG Sbjct: 78 IGAGFVGFGSDGRVLIDYARQLAIQYKFIYGEKIPVEYLTRQICDLMQLYTQHGGVRPFG 137 Query: 450 ISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENGAV 629 ++ LI G D D P LF EPSG Y +KA+ G+ E L++ Y D++ E GA+ Sbjct: 138 VTLLIVGVD-DSGPKLFVAEPSGQYMSYKAHGLGQGGGQAIEILQREY-RDDIDVE-GAI 194 Query: 630 KLAIRALLEVVQ 665 L IRA+ V++ Sbjct: 195 LLGIRAVASVME 206 >UniRef50_Q017X9 Cluster: Alpha 2 subunit of 20S proteasome; n=6; Eukaryota|Rep: Alpha 2 subunit of 20S proteasome - Ostreococcus tauri Length = 270 Score = 134 bits (324), Expect = 2e-30 Identities = 69/192 (35%), Positives = 113/192 (58%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 ++T FSP G L+Q+++A A+ G+T+ EKK + L + TV+KI L Sbjct: 44 SLTTFSPSGELVQIKHALAAISAGATSLGIKAVDGVVLATEKKLPSTLVDASTVKKIATL 103 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 D + +A++G+ D R+L A+ E Q++ T ++ + + + R A + Q++TQ G R Sbjct: 104 TDDIGIAYSGMGPDFRVLTRMARKETQTYYRTYKESIPVSQLVRETATVMQEFTQQGGVR 163 Query: 441 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATEN 620 PFG+S L+ G+D G P L+Q +PSG Y+ WKA+A G++ + FLEK Y +D++ E+ Sbjct: 164 PFGVSLLMAGYDESG-PSLYQVDPSGSYFAWKASAIGKNMVNAKTFLEKRY-SDDIELED 221 Query: 621 GAVKLAIRALLE 656 A+ AI L E Sbjct: 222 -AIHTAILTLKE 232 >UniRef50_Q27562 Cluster: Proteasome subunit alpha type-1; n=6; Eukaryota|Rep: Proteasome subunit alpha type-1 - Dictyostelium discoideum (Slime mold) Length = 248 Score = 134 bits (323), Expect = 2e-30 Identities = 69/193 (35%), Positives = 114/193 (59%) Frame = +3 Query: 84 ITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLD 263 IT FSP G + Q+EYA EAV++G A K+S ++L + +KI ++D Sbjct: 10 ITTFSPSGRIHQIEYAMEAVKQGGAAVALKSKQFAVLVSLKRSSSELGSYQ--KKIFVVD 67 Query: 264 DHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRP 443 DHV +A +GLTADAR+L N + EC ++ E + +E + +A Q +TQ GRRP Sbjct: 68 DHVGIAISGLTADARMLCNYMRNECSNYNYVYESQMRVERLVTKVADKHQVHTQRYGRRP 127 Query: 444 FGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENG 623 +G+ L+ G+D G+ H++QT PSG +Y++K+ + G +++ + +LEK++ + E T Sbjct: 128 YGVGLLVAGYDQLGA-HIYQTCPSGNFYDYKSISIGSRSQSAKTYLEKHFESFEECTLEQ 186 Query: 624 AVKLAIRALLEVV 662 + +RAL E + Sbjct: 187 LITHGLRALRETI 199 >UniRef50_A2ST52 Cluster: Proteasome alpha subunit; n=1; Methanocorpusculum labreanum Z|Rep: Proteasome alpha subunit - Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z) Length = 272 Score = 133 bits (321), Expect = 4e-30 Identities = 72/193 (37%), Positives = 112/193 (58%), Gaps = 3/193 (1%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 AIT+FSPDG L QVEYA+EAV++G+TA +K+ ++L E ++ KI + Sbjct: 14 AITMFSPDGRLYQVEYAREAVKRGTTAVGIKCKTGVVLLVDKRVNSRLLEPSSIEKIFRI 73 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 D+H+ +A +GL DARIL++RA+IE Q ++++ +PV +E + + + Q YT G R Sbjct: 74 DEHIGVASSGLVGDARILVDRARIEAQINRVSYGEPVDVETLAKKLCDHMQSYTLFGGAR 133 Query: 441 PFGISCLIGGFDYDGSP---HLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVA 611 P+G + LI G + + HLF+T+PSG E+ A G V + E+ Y E Sbjct: 134 PYGTALLIAGAESSPTGTKYHLFETDPSGTLLEYSATGIGIGRPAVIKLFEQEY--KETC 191 Query: 612 TENGAVKLAIRAL 650 + AV L ++AL Sbjct: 192 SAEEAVLLGLKAL 204 >UniRef50_A7D1R0 Cluster: Proteasome endopeptidase complex; n=2; Halorubrum lacusprofundi ATCC 49239|Rep: Proteasome endopeptidase complex - Halorubrum lacusprofundi ATCC 49239 Length = 268 Score = 132 bits (319), Expect = 7e-30 Identities = 73/188 (38%), Positives = 111/188 (59%) Frame = +3 Query: 87 TVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDD 266 ++FSPDG + QVEYA+EAV +G+ + + + L E ++ K+ LDD Sbjct: 15 SLFSPDGRIYQVEYAREAVSRGAPSVGVRTADGVVFVAMSRPSSTLMEAESIEKLHKLDD 74 Query: 267 HVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPF 446 H+ A AG ADAR LI+ A+ + Q ++L +PV +E +T+++ Q+ TQ G RP+ Sbjct: 75 HLGTASAGHVADARQLIDLARRQSQGNRLRYGEPVGVETLTKFVTDHIQENTQRGGTRPY 134 Query: 447 GISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENGA 626 G + LIGG D +G P LF +PSG EWKA G ++ LE+N+T +E++ + G Sbjct: 135 GAALLIGGID-NGEPRLFAADPSGTPNEWKATVIGGGRSDIQGHLEENWT-EELSLDAG- 191 Query: 627 VKLAIRAL 650 V+LAI AL Sbjct: 192 VELAIAAL 199 >UniRef50_P23638 Cluster: Proteasome component Y13; n=3; Saccharomycetaceae|Rep: Proteasome component Y13 - Saccharomyces cerevisiae (Baker's yeast) Length = 258 Score = 130 bits (315), Expect = 2e-29 Identities = 70/195 (35%), Positives = 110/195 (56%), Gaps = 1/195 (0%) Frame = +3 Query: 87 TVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERT-VRKICLLD 263 T+FSP+G L QVEYA E++ TA E+K + L E+ T K+ L+ Sbjct: 11 TIFSPEGRLYQVEYALESISHAGTAIGIMASDGIVLAAERKVTSTLLEQDTSTEKLYKLN 70 Query: 264 DHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRP 443 D + +A AGLTADA ILIN A+I Q++ T + + +E + R ++ +KQ YTQ G RP Sbjct: 71 DKIAVAVAGLTADAEILINTARIHAQNYLKTYNEDIPVEILVRRLSDIKQGYTQHGGLRP 130 Query: 444 FGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENG 623 FG+S + G+D L+ + PSG Y WKA + G + + L+ +Y D++ ++ Sbjct: 131 FGVSFIYAGYDDRYGYQLYTSNPSGNYTGWKAISVGANTSAAQTLLQMDY-KDDMKVDD- 188 Query: 624 AVKLAIRALLEVVQS 668 A++LA++ L + S Sbjct: 189 AIELALKTLSKTTDS 203 >UniRef50_Q7QZC5 Cluster: GLP_43_57537_58271; n=3; Giardia intestinalis|Rep: GLP_43_57537_58271 - Giardia lamblia ATCC 50803 Length = 244 Score = 130 bits (314), Expect = 3e-29 Identities = 70/191 (36%), Positives = 107/191 (56%), Gaps = 1/191 (0%) Frame = +3 Query: 87 TVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDD 266 T+FS DG LLQVEYA +AV + +KK +KL +++T KI +D Sbjct: 9 TLFSQDGRLLQVEYAIKAVTIAAPCLAILAQDGIVFVAQKKLPSKLSDQQTSEKIYKIDS 68 Query: 267 HVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPF 446 H+V A +GLT+DA ILI+ A+ Q ++P+ +E + +YI+ +KQ YT G RP+ Sbjct: 69 HIVCAVSGLTSDANILIDEARTYSQKWLAVYDEPIPVEVLVQYISDVKQNYTHHGGLRPY 128 Query: 447 GISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYT-ADEVATENG 623 G+S L GG+D L+QT+PSG Y W A + G SA + L++N + + Sbjct: 129 GVSFLFGGWDAHLGFQLYQTDPSGNYSAWVATSIGGSAPEIASALKQNIADSSQKILLKE 188 Query: 624 AVKLAIRALLE 656 A + A+ AL++ Sbjct: 189 AQQYAVSALIK 199 >UniRef50_Q09682 Cluster: Probable proteasome subunit alpha type-4; n=5; Eukaryota|Rep: Probable proteasome subunit alpha type-4 - Schizosaccharomyces pombe (Fission yeast) Length = 248 Score = 130 bits (314), Expect = 3e-29 Identities = 73/195 (37%), Positives = 108/195 (55%), Gaps = 1/195 (0%) Frame = +3 Query: 87 TVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKL-QEERTVRKICLLD 263 T+FSP+G L QVEYA EA+ A EKK +KL ++E + K+ + Sbjct: 10 TIFSPEGRLYQVEYALEAINHAGVALGIVAKDGIVLAAEKKVTSKLLEQEESAEKLYHIG 69 Query: 264 DHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRP 443 D+++ A AGLTADA ILIN A+ Q + T + + E + R + LKQ YTQ G RP Sbjct: 70 DNMLCAVAGLTADANILINYARRVGQQYLQTFNEEMPCEQLVRRVCDLKQGYTQYGGLRP 129 Query: 444 FGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENG 623 FG+S L G+D+ LFQ+ PSG Y W+AN+ G ++ +V+ + + Y D E Sbjct: 130 FGVSFLYAGWDHIRGYQLFQSNPSGNYGSWQANSIGGNSTSVQSLMRQEYKDDINLDEAS 189 Query: 624 AVKLAIRALLEVVQS 668 A +A++ L + + S Sbjct: 190 A--MAVKFLSKTLDS 202 >UniRef50_Q94561 Cluster: Proteasome subunit alpha type-5; n=2; Eukaryota|Rep: Proteasome subunit alpha type-5 - Entamoeba histolytica Length = 247 Score = 129 bits (311), Expect = 7e-29 Identities = 70/199 (35%), Positives = 111/199 (55%), Gaps = 5/199 (2%) Frame = +3 Query: 84 ITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLD 263 + FS +G L QVEYA EA++ GST EK+ + L ++ KI +D Sbjct: 12 VNTFSSEGRLFQVEYATEAMKLGSTVIGIQTKEGVVLAVEKRISSPLMLGSSIEKIIEID 71 Query: 264 DHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGR-- 437 DH+ A +GLTADAR LI+ A++E Q+H+ ++P+ +E + + I+ L ++ + + + Sbjct: 72 DHIGAAVSGLTADARTLIDNARLEAQNHRFMYDEPINVEVVAQAISDLSLRFGEGSRKKK 131 Query: 438 ---RPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEV 608 RPFG++ LI G D G P LFQT+PSG++ E+ A ATG + + L + Y Sbjct: 132 VMSRPFGVALLIAGVDETG-PRLFQTDPSGMFIEFYAKATGAGTEAAQSILHEKYNKSMT 190 Query: 609 ATENGAVKLAIRALLEVVQ 665 E A LA+ L +V++ Sbjct: 191 LRE--AEILALSTLKQVME 207 >UniRef50_Q5CQL5 Cluster: Proteasome subunit alpha type; n=9; Eukaryota|Rep: Proteasome subunit alpha type - Cryptosporidium parvum Iowa II Length = 271 Score = 127 bits (307), Expect = 2e-28 Identities = 65/173 (37%), Positives = 99/173 (57%), Gaps = 1/173 (0%) Frame = +3 Query: 87 TVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEE-RTVRKICLLD 263 T FSP+G L QVEYA EA+ + +K V+KL ++ +++ KI +D Sbjct: 20 TTFSPEGRLYQVEYALEAINNAAPTVGILCKEGVILGADKAIVSKLLDQGKSLEKIYTID 79 Query: 264 DHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRP 443 H++ A AGLTADA ILI +A+I+ Q ++ T + +E + I KQ YTQ G RP Sbjct: 80 RHIIAAVAGLTADANILIAQARIDSQRYQYTYGEEQPVEQLVTQICDRKQSYTQFGGLRP 139 Query: 444 FGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTAD 602 FG+S L G+D + L+Q++PSG + WKA A G++ +T L++ + D Sbjct: 140 FGVSFLFAGYDKNYGYQLYQSDPSGNFSGWKATAIGQNNQTATSLLKQEWNED 192 >UniRef50_P34119 Cluster: Proteasome subunit alpha type-4; n=4; Eukaryota|Rep: Proteasome subunit alpha type-4 - Dictyostelium discoideum (Slime mold) Length = 250 Score = 126 bits (305), Expect = 4e-28 Identities = 71/195 (36%), Positives = 106/195 (54%), Gaps = 3/195 (1%) Frame = +3 Query: 87 TVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTV--RKICLL 260 T+FSP+G + QVEYA A+R EKK+ AKL + T K+ + Sbjct: 10 TIFSPEGRVYQVEYAMTAIRHAGATVGILAKDGIVLAAEKKTTAKLLDSSTSISEKMFKI 69 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 D+HVV A AG+T+DA ILIN A++ Q ++P+ +E + I KQ YTQ G R Sbjct: 70 DEHVVCAVAGITSDANILINYARLSSQRFFYQYQEPMPVEQLVSQICDTKQGYTQYGGLR 129 Query: 441 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANAT-GRSAKTVREFLEKNYTADEVATE 617 PFG+S L G+D L+Q++PSG + WKA + G +++ + L NY D E Sbjct: 130 PFGVSFLYAGWDRHYGFQLYQSDPSGNFAGWKATSIGGENSQVAQSVLRSNYKPDISLKE 189 Query: 618 NGAVKLAIRALLEVV 662 A++LA++ L + + Sbjct: 190 --ALQLALKVLTKTM 202 >UniRef50_P34066 Cluster: Proteasome subunit alpha type-1-A; n=4; core eudicotyledons|Rep: Proteasome subunit alpha type-1-A - Arabidopsis thaliana (Mouse-ear cress) Length = 278 Score = 126 bits (303), Expect = 6e-28 Identities = 68/194 (35%), Positives = 109/194 (56%) Frame = +3 Query: 84 ITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLD 263 +T +SP G L QVEYA EAV++GS A K+ ++L + RKI +D Sbjct: 10 VTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLACVNKAQSELSSHQ--RKIFKVD 67 Query: 264 DHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRP 443 DH+ +A AGLTAD R+L + E +H T E P+ + + ++A Q TQ + +RP Sbjct: 68 DHIGVAIAGLTADGRVLSRYMRSESINHSFTYESPLPVGRLVVHLADKAQVCTQRSWKRP 127 Query: 444 FGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENG 623 +G+ L+GG D G+ HL+ PSG Y+E++A A G ++ + +LE+ + + ++ Sbjct: 128 YGVGLLVGGLDESGA-HLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERRFESFGDSSRED 186 Query: 624 AVKLAIRALLEVVQ 665 +K AI A+ E +Q Sbjct: 187 LIKDAILAVRETLQ 200 >UniRef50_P25786 Cluster: Proteasome subunit alpha type-1; n=77; Fungi/Metazoa group|Rep: Proteasome subunit alpha type-1 - Homo sapiens (Human) Length = 263 Score = 123 bits (297), Expect = 3e-27 Identities = 67/193 (34%), Positives = 108/193 (55%) Frame = +3 Query: 84 ITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLD 263 +TV+SP G + Q+EYA EAV++GS K++ ++L + +KI +D Sbjct: 10 VTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQ--KKILHVD 67 Query: 264 DHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRP 443 +H+ ++ AGLTADAR+L N + EC + + P+ + + I Q TQ GRRP Sbjct: 68 NHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRYGRRP 127 Query: 444 FGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENG 623 +G+ LI G+D D PH+FQT PS Y++ +A + G +++ R +LE++ + N Sbjct: 128 YGVGLLIAGYD-DMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMECNLNE 186 Query: 624 AVKLAIRALLEVV 662 VK +RAL E + Sbjct: 187 LVKHGLRALRETL 199 >UniRef50_A0CZU2 Cluster: Chromosome undetermined scaffold_32, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_32, whole genome shotgun sequence - Paramecium tetraurelia Length = 249 Score = 121 bits (292), Expect = 1e-26 Identities = 69/193 (35%), Positives = 104/193 (53%), Gaps = 1/193 (0%) Frame = +3 Query: 93 FSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEE-RTVRKICLLDDH 269 F+PDG L QVEYA EA+ + +A EK+ V+ L E + KI +D H Sbjct: 12 FTPDGRLKQVEYAIEAINQTGSALGVLTNEGMILATEKQEVSHLLEHSKHSEKIYPIDRH 71 Query: 270 VVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFG 449 + +G TADA ILIN A+ +H+ +D + LE + I KQ TQ G+RPFG Sbjct: 72 IFSVVSGHTADANILINYAREAAANHRYQFQDNIALEQLIINICDYKQNKTQVGGQRPFG 131 Query: 450 ISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENGAV 629 + L G+D LF T+PSG Y WKA A G++ +L+++Y + + E G + Sbjct: 132 TAFLFAGYDKKNGFQLFSTDPSGNYAGWKATAIGKNNLAANSYLKQDY-KENLTLEQG-L 189 Query: 630 KLAIRALLEVVQS 668 +AI+AL++ + + Sbjct: 190 DIAIKALVKTMDT 202 >UniRef50_P25789 Cluster: Proteasome subunit alpha type-4; n=113; Eukaryota|Rep: Proteasome subunit alpha type-4 - Homo sapiens (Human) Length = 261 Score = 121 bits (292), Expect = 1e-26 Identities = 65/189 (34%), Positives = 103/189 (54%), Gaps = 1/189 (0%) Frame = +3 Query: 87 TVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTV-RKICLLD 263 T+FSP+G L QVEYA EA+ T E++++ KL +E KI L+ Sbjct: 10 TIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEKIYKLN 69 Query: 264 DHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRP 443 + + + AG+T+DA +L N ++ Q + L ++P+ E + + +KQ YTQ G+RP Sbjct: 70 EDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRP 129 Query: 444 FGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENG 623 FG+S L G+D L+Q++PSG Y WKA G ++ L+++Y E+ T Sbjct: 130 FGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEM-TLKS 188 Query: 624 AVKLAIRAL 650 A+ LAI+ L Sbjct: 189 ALALAIKVL 197 >UniRef50_Q4CKY8 Cluster: Proteasome alpha 2 subunit, putative; n=1; Trypanosoma cruzi|Rep: Proteasome alpha 2 subunit, putative - Trypanosoma cruzi Length = 179 Score = 121 bits (291), Expect = 2e-26 Identities = 58/140 (41%), Positives = 91/140 (65%) Frame = +3 Query: 237 TVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQK 416 TV+K+ +LDDHV ++G+ D R+L++ A+ CQ ++LT +P+ + + R I+ L Q+ Sbjct: 7 TVQKVFVLDDHVGCTYSGIGPDCRVLVDAARKACQKYRLTYHEPMPVSQLVRQISSLYQE 66 Query: 417 YTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYT 596 +TQS G RPFG S L+ G D G+ HL+Q +PSG ++ WKA + G+ + + FLEK YT Sbjct: 67 FTQSGGVRPFGCSLLVAGADSQGN-HLYQVDPSGTFWAWKATSIGKGSTDAKTFLEKRYT 125 Query: 597 ADEVATENGAVKLAIRALLE 656 +E+ E+ AV A+ L E Sbjct: 126 -NEMEIED-AVHTALLTLKE 143 >UniRef50_P28066 Cluster: Proteasome subunit alpha type-5; n=115; Eukaryota|Rep: Proteasome subunit alpha type-5 - Homo sapiens (Human) Length = 241 Score = 120 bits (289), Expect = 3e-26 Identities = 66/199 (33%), Positives = 111/199 (55%), Gaps = 5/199 (2%) Frame = +3 Query: 84 ITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLD 263 + FSP+G L QVEYA EA++ GSTA EK+ + L E ++ KI +D Sbjct: 12 VNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSIEKIVEID 71 Query: 264 DHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNG--- 434 H+ A +GL ADA+ LI++A++E Q+H T + +T+E +T+ ++ L ++ + + Sbjct: 72 AHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLALQFGEEDADPG 131 Query: 435 --RRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEV 608 RPFG++ L GG D G P LF +PSG + + A A G +++ + L++ Y Sbjct: 132 AMSRPFGVALLFGGVDEKG-PQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHKSMT 190 Query: 609 ATENGAVKLAIRALLEVVQ 665 E A+K ++ L +V++ Sbjct: 191 LKE--AIKSSLIILKQVME 207 >UniRef50_A2FCM7 Cluster: Proteasome subunit alpha type; n=2; Trichomonas vaginalis|Rep: Proteasome subunit alpha type - Trichomonas vaginalis G3 Length = 251 Score = 120 bits (288), Expect = 4e-26 Identities = 68/201 (33%), Positives = 108/201 (53%), Gaps = 7/201 (3%) Frame = +3 Query: 84 ITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLD 263 + FSPDG LLQVEYA EAV+ GS+A EK+ ++L +V K+ +D Sbjct: 12 VNTFSPDGRLLQVEYAIEAVKLGSSAVAILCPEGVIFAVEKRLSSQLLIASSVEKVYAID 71 Query: 264 DHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGL-------KQKYT 422 DHV + AGL AD R ++ ++E Q+H+ + ++P+ ++ +T+ + L ++K Sbjct: 72 DHVGVVMAGLAADGRTMVEHMRVEAQNHRFSFDEPIGIKAVTQSVCDLALAFGEGRRKKG 131 Query: 423 QSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTAD 602 RPFG + L+ G + +G HLF T+PSG Y E +A A G ++ L Y Sbjct: 132 DGQMSRPFGTALLVAGIE-NGKCHLFHTDPSGTYTECRARAIGGGSEGAEALLRDLY--K 188 Query: 603 EVATENGAVKLAIRALLEVVQ 665 + T + A LA+ L +V+Q Sbjct: 189 DGMTLHEAEDLALSTLRQVIQ 209 >UniRef50_Q5CTQ7 Cluster: Proteasome subunit alpha type; n=3; Cryptosporidium|Rep: Proteasome subunit alpha type - Cryptosporidium parvum Iowa II Length = 288 Score = 119 bits (287), Expect = 6e-26 Identities = 61/195 (31%), Positives = 108/195 (55%) Frame = +3 Query: 84 ITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLD 263 + +SP G + Q+EYA EAV++G+ K+S ++L + +K+ +D Sbjct: 39 VVTWSPQGRVFQIEYAMEAVKQGTAVVGARNDEIVVLACIKRSTSRLAGYQ--KKLYKID 96 Query: 264 DHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRP 443 +H+ +A +G+TADA+++ N + EC ++ T + P+ L + + Q TQ GRRP Sbjct: 97 NHIGVAVSGITADAKVICNYLRSECLNYSFTYDSPIPLNTLVNRLVLKSQVNTQEYGRRP 156 Query: 444 FGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENG 623 FG+ L+ GFD G PHLF+T PSG +E+ + A G ++ + +LEK++ +++ Sbjct: 157 FGVGLLLAGFDESG-PHLFETCPSGNCFEYYSIAIGSRSQASKTYLEKHFKEFANCSKDQ 215 Query: 624 AVKLAIRALLEVVQS 668 + +RAL + S Sbjct: 216 LILHTLRALRSSLSS 230 >UniRef50_Q55YJ2 Cluster: Proteasome subunit alpha type; n=3; Basidiomycota|Rep: Proteasome subunit alpha type - Cryptococcus neoformans (Filobasidiella neoformans) Length = 299 Score = 118 bits (285), Expect = 1e-25 Identities = 68/193 (35%), Positives = 105/193 (54%) Frame = +3 Query: 87 TVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDD 266 T FSP G L QVEYA EAV++GS A K+S +L + +K+ +DD Sbjct: 11 TTFSPQGKLFQVEYALEAVKQGSAAIGLRSNTHAVLLTLKRSTGELATYQ--KKLIRIDD 68 Query: 267 HVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPF 446 HV +A AGLT+DAR+L N + + ++T + + + IA Q TQ GRRP+ Sbjct: 69 HVGVAIAGLTSDARVLSNYMRQKAMQSRMTYGRATPVARLVQSIADRAQTNTQEYGRRPY 128 Query: 447 GISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENGA 626 G+ L+ G D G PHLF+ P+G +E+ A++ G +++ + +LEKNY A+ Sbjct: 129 GVGFLVIGKDETG-PHLFEFSPAGTAFEYYAHSIGARSQSAKTYLEKNYHLFPNASLEEL 187 Query: 627 VKLAIRALLEVVQ 665 + + AL + +Q Sbjct: 188 INHGLSALHDTLQ 200 >UniRef50_P52428 Cluster: Proteasome subunit alpha type-1; n=4; Oryza sativa|Rep: Proteasome subunit alpha type-1 - Oryza sativa subsp. japonica (Rice) Length = 270 Score = 118 bits (283), Expect = 2e-25 Identities = 64/194 (32%), Positives = 102/194 (52%) Frame = +3 Query: 84 ITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLD 263 +T +SP G L QVEYA EAV++GS K+ ++L + RK+ + Sbjct: 10 VTTWSPAGRLFQVEYAMEAVKQGSACVGLRSRTHAVLAAANKAASELSSHQ--RKVFRVA 67 Query: 264 DHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRP 443 DH +A AGLTAD R+L + EC +H + P+ + + +A Q TQ + +RP Sbjct: 68 DHAGVALAGLTADGRVLSRFLRSECINHAFVYDAPLPVSRLALRLADKAQVCTQRSWKRP 127 Query: 444 FGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENG 623 +G+ L+ G D G+ HL+ PSG Y+E++A A G ++ + FLE+ + T Sbjct: 128 YGVGLLVAGLDESGA-HLYYNCPSGNYFEYQAFAIGSRSQAAKTFLERRFEGYNDYTPEQ 186 Query: 624 AVKLAIRALLEVVQ 665 +K A+ A+ E +Q Sbjct: 187 LIKDALSAIKETLQ 200 >UniRef50_Q2GW78 Cluster: Proteasome subunit alpha type; n=4; Pezizomycotina|Rep: Proteasome subunit alpha type - Chaetomium globosum (Soil fungus) Length = 267 Score = 117 bits (282), Expect = 2e-25 Identities = 66/188 (35%), Positives = 99/188 (52%) Frame = +3 Query: 93 FSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDDHV 272 FSP G + QVEYA EAV++GS K++ +L + +K+ +D+HV Sbjct: 13 FSPQGRIFQVEYAAEAVKQGSVVVGIASKTHVVLVAIKRNAEELSSYQ--KKLFPIDEHV 70 Query: 273 VMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFGI 452 +A AGLT+DAR+L N + +C H+LT + + + I Q TQ G+RP+G+ Sbjct: 71 GIAIAGLTSDARVLSNFMKQQCLGHRLTFGRSMPVRTLVEIIGSKAQINTQHYGKRPYGV 130 Query: 453 SCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENGAVK 632 L+ G D D PHLF+ +PSG+ E A A G ++ R +LEKN ++ Sbjct: 131 GLLVAGVD-DHGPHLFEFQPSGMTEEMVAFAIGARSQMARTYLEKNIDKFADCDREELIR 189 Query: 633 LAIRALLE 656 +RAL E Sbjct: 190 HGLRALKE 197 >UniRef50_A5K435 Cluster: Proteosome subunit alpha type 1, putative; n=5; Plasmodium|Rep: Proteosome subunit alpha type 1, putative - Plasmodium vivax Length = 269 Score = 111 bits (268), Expect = 1e-23 Identities = 55/166 (33%), Positives = 97/166 (58%) Frame = +3 Query: 93 FSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDDHV 272 +SP+G L QVEYA EA+++G+ A KK ++KL + K+ +DD++ Sbjct: 13 YSPEGRLYQVEYANEAIKQGTCAVAIKSKDFVVVCGLKKRISKLSFHQ--EKLFKIDDYI 70 Query: 273 VMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFGI 452 + +G+T+DA++L + EC SHK ++ + +E + + +A Q+ TQ + RR FG+ Sbjct: 71 GVTMSGITSDAKVLTKYMRNECLSHKFLFDENMNIEKLVKKVADKYQQNTQRSSRRAFGV 130 Query: 453 SCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKN 590 +I G Y P++F+T+P+G Y+E+ A + G + + +LEKN Sbjct: 131 GLIIAG--YFKEPYIFETKPNGSYFEYIALSFGARSHASKTYLEKN 174 >UniRef50_O96788 Cluster: Proteasome subunit alpha type-1; n=10; Trypanosomatidae|Rep: Proteasome subunit alpha type-1 - Trypanosoma brucei rhodesiense Length = 266 Score = 111 bits (267), Expect = 1e-23 Identities = 67/196 (34%), Positives = 98/196 (50%), Gaps = 1/196 (0%) Frame = +3 Query: 87 TVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKS-VAKLQEERTVRKICLLD 263 T +SP G L QVEYA EAV GS A K++ V+ L + K LD Sbjct: 11 TTWSPTGRLFQVEYANEAVNNGSAAVGVKGADYVVLTALKRNPVSGLSSYQ--EKAFKLD 68 Query: 264 DHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRP 443 +HV MA +GL AD R L + EC +++ + L + + Q++ Q G+RP Sbjct: 69 EHVGMAISGLVADGRALSRFLRTECMNYRYMHDSDAPLVMLADIVGAKHQRHIQFAGKRP 128 Query: 444 FGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENG 623 FG+ LI G+D G P L+QT PSG +++KA A G ++ R +LE+++ + Sbjct: 129 FGVGLLIAGYDRQG-PRLYQTVPSGDVFDFKATAMGLRSQAARTYLERHFRGFPACDLDE 187 Query: 624 AVKLAIRALLEVVQSG 671 V A+RAL G Sbjct: 188 LVMHALRALGAATSGG 203 >UniRef50_Q4QFV4 Cluster: Proteasome subunit alpha type; n=7; Trypanosomatidae|Rep: Proteasome subunit alpha type - Leishmania major Length = 285 Score = 110 bits (265), Expect = 3e-23 Identities = 64/195 (32%), Positives = 104/195 (53%), Gaps = 7/195 (3%) Frame = +3 Query: 87 TVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVR------- 245 T FSP+G L QVEYA EA+++ T EK L + ++ Sbjct: 10 TTFSPEGRLYQVEYAVEAIQQAGTVIGVCTKDGVVLAGEKMVPHPLFDSENMQDKNISGE 69 Query: 246 KICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQ 425 K+ + +H+ + AG+T+DA L+N A++ H+ T ++P+ +E + R + KQ YTQ Sbjct: 70 KMYKIAEHIGCSVAGVTSDAYALLNYARLSALRHQYTFQEPIAIEDLCRILCDEKQLYTQ 129 Query: 426 SNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADE 605 G RP+G+S L+ G+D L+ TEPSG Y W A A G++ + L+K++ + Sbjct: 130 YGGVRPYGVSFLLVGWDRYYGYQLYSTEPSGDYSAWSAYAIGQNDQVAHSLLKKDW-HEN 188 Query: 606 VATENGAVKLAIRAL 650 + E+G + LA+R L Sbjct: 189 MTLEDGML-LALRVL 202 >UniRef50_UPI0000E48E53 Cluster: PREDICTED: similar to Proteasome (prosome macropain) subunit alpha type 4; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Proteasome (prosome macropain) subunit alpha type 4 - Strongylocentrotus purpuratus Length = 257 Score = 109 bits (263), Expect = 5e-23 Identities = 59/189 (31%), Positives = 101/189 (53%), Gaps = 1/189 (0%) Frame = +3 Query: 87 TVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVR-KICLLD 263 T+FSP+G L QVEYA EA+ T+ E+++ KL ++ KI L+ Sbjct: 10 TIFSPEGRLYQVEYAMEAIGHAGTSLGILASDGVLLAAERRNTHKLLDDVVFSDKIYKLN 69 Query: 264 DHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRP 443 + + +G+T+DA +L + ++ Q + L ++ + E + + +KQ YTQ+ G+RP Sbjct: 70 SDMACSVSGITSDANVLTSELRLAGQRYFLQYQENIPNEQLVSTLCDIKQFYTQAGGKRP 129 Query: 444 FGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENG 623 FG+S L G+D L+Q++PSG Y WKA G ++ L++ Y + + G Sbjct: 130 FGVSILYMGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAISMLKQEYKEGDTDLK-G 188 Query: 624 AVKLAIRAL 650 A+ LA++ L Sbjct: 189 ALALAVKVL 197 >UniRef50_P21242 Cluster: Proteasome component C1; n=18; Eukaryota|Rep: Proteasome component C1 - Saccharomyces cerevisiae (Baker's yeast) Length = 288 Score = 109 bits (262), Expect = 6e-23 Identities = 60/167 (35%), Positives = 89/167 (53%) Frame = +3 Query: 87 TVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDD 266 +VFSPDG QVEYA +AV G+T+ EK +KL + KI ++D Sbjct: 13 SVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVKIQVVDR 72 Query: 267 HVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPF 446 H+ ++GL D R L+NR + E S K + P+ + + Q +T N RPF Sbjct: 73 HIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPF 132 Query: 447 GISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 587 G+S + GG D +G+ HL+ EPSG Y+ +K ATG+ ++ + LEK Sbjct: 133 GVSTIFGGVDKNGA-HLYMLEPSGSYWGYKGAATGKGRQSAKAELEK 178 >UniRef50_O81146 Cluster: Proteasome subunit alpha type-6-A; n=15; Eukaryota|Rep: Proteasome subunit alpha type-6-A - Arabidopsis thaliana (Mouse-ear cress) Length = 246 Score = 107 bits (257), Expect = 2e-22 Identities = 61/195 (31%), Positives = 102/195 (52%), Gaps = 1/195 (0%) Frame = +3 Query: 84 ITVFSPDGHLLQVEYAQEAVRK-GSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 IT+FSP+G L QVEYA +AV+ G T+ +KK KL ++ +V + + Sbjct: 13 ITIFSPEGRLFQVEYAFKAVKTAGITSIGVRGKDSVCVVTQKKVPDKLLDQSSVTHLFPI 72 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 ++ + G+TADAR L+ +A+ + + T + ++ + ++IA Q YTQ R Sbjct: 73 TKYIGLVATGITADARSLVQQARNQAAEFRFTYGYEMPVDILAKWIADKSQVYTQHAYMR 132 Query: 441 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATEN 620 P G+ ++ G D + P L++ +P+G +Y KA + G + FLEK + T + Sbjct: 133 PLGVVAMVMGVDEENGPLLYKCDPAGHFYGHKATSAGMKEQEAVNFLEKKMKENPSFTFD 192 Query: 621 GAVKLAIRALLEVVQ 665 V+ AI AL V+Q Sbjct: 193 ETVQTAISALQSVLQ 207 >UniRef50_A7AV06 Cluster: Proteasome subunit alpha type 1; n=1; Babesia bovis|Rep: Proteasome subunit alpha type 1 - Babesia bovis Length = 257 Score = 106 bits (255), Expect = 4e-22 Identities = 56/192 (29%), Positives = 100/192 (52%) Frame = +3 Query: 93 FSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDDHV 272 +SP G L QVEYA EAV++G+ ++ +KL E + KI + +H+ Sbjct: 13 WSPQGRLFQVEYAMEAVKQGTCCVGIKSQTHIVLCAVRRKSSKLAEYQD--KIFCIGEHI 70 Query: 273 VMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFGI 452 + +G+T+DA++++N + EC ++K +T + IA Q TQ++ +RPFG+ Sbjct: 71 AVVMSGITSDAKMIVNYMRNECLNNKFLYGCDITATKLVSLIAQKSQANTQTSSKRPFGV 130 Query: 453 SCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENGAVK 632 L+ G+D HL++T PSG E+ A A G ++ + +LE+ E + + Sbjct: 131 GLLVAGYDDRTGLHLYETCPSGNVVEYNATAFGARCQSAKTYLERKIANFEECNIDSLIY 190 Query: 633 LAIRALLEVVQS 668 A++A+ + S Sbjct: 191 HAVKAVKMTIPS 202 >UniRef50_Q8SRU3 Cluster: 26S PROTEASOME ZETA CHAIN; n=4; Microsporidia|Rep: 26S PROTEASOME ZETA CHAIN - Encephalitozoon cuniculi Length = 232 Score = 106 bits (255), Expect = 4e-22 Identities = 53/176 (30%), Positives = 96/176 (54%), Gaps = 5/176 (2%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 ++ +S +G + Q+EYA +A+ G+T EKK ++ LQ ++V K + Sbjct: 7 SVNTYSSEGRIHQIEYAMKAMNLGTTTIGVRTKEFVILCSEKKILSTLQNPKSVVKHYKI 66 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNG-- 434 DH+V+ F+G++ D + ++ R++ C SH + +++E + +Y++ L ++ + + Sbjct: 67 YDHIVLGFSGISGDTKTIVKRSRDFCISHTHMYGENISVERLLKYLSSLSLRFGEEDEAK 126 Query: 435 ---RRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 593 RRPFG+S +I GFD + P L+ +PSG Y +KA A G + V LE Y Sbjct: 127 MIFRRPFGVSLIIAGFDTE--PRLYSLDPSGSYISYKAKAIGSGHEVVEGILENEY 180 >UniRef50_A7AW04 Cluster: Proteasome alpha 5 subunit, putative; n=1; Babesia bovis|Rep: Proteasome alpha 5 subunit, putative - Babesia bovis Length = 250 Score = 106 bits (254), Expect = 6e-22 Identities = 56/180 (31%), Positives = 93/180 (51%), Gaps = 7/180 (3%) Frame = +3 Query: 84 ITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLD 263 + FSP+G + QVEYA A++ GSTA E + + L E ++ KI +D Sbjct: 12 VNTFSPEGRIFQVEYALGAIKLGSTALAIATKEGVIFASEHRVNSPLMESVSLEKIMEID 71 Query: 264 DHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYT------- 422 H+ +GL ADAR LI+ ++EC +H+ +P+ + IA + ++ Sbjct: 72 THIGCTMSGLIADARTLIDHGRLECANHRFVYNEPLAIRSCVESIADMALDFSDIFDTRK 131 Query: 423 QSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTAD 602 + RPFG++ L+GG D DG P ++ +PSG ++KA+A G + + L++ Y D Sbjct: 132 KKTMSRPFGVALLVGGIDIDG-PSIWCVDPSGTSIKYKASAIGSAQEGAESVLQERYRDD 190 >UniRef50_Q4N3Q8 Cluster: Proteasome subunit alpha type 1, putative; n=2; Theileria|Rep: Proteasome subunit alpha type 1, putative - Theileria parva Length = 252 Score = 104 bits (250), Expect = 2e-21 Identities = 55/186 (29%), Positives = 100/186 (53%) Frame = +3 Query: 93 FSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDDHV 272 +SP G L QVEYA E+V++G+ K+ ++KL + + K+ + +++ Sbjct: 13 WSPQGRLFQVEYAMESVKQGTCCVGIKSNTHLVLCALKRKISKLAQVQD--KLYKVGEYI 70 Query: 273 VMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFGI 452 +A +G+T+DA+++I+ + EC S++ +T + ++ Q TQ + +RPFG+ Sbjct: 71 GVAMSGITSDAKMIISYMRNECLSNRFLYGCDITASQLVSLVSEKSQANTQVSSKRPFGV 130 Query: 453 SCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENGAVK 632 L+ G+D HLF+T PSG E+ A A G ++ + +LE+ + NG + Sbjct: 131 GLLVAGYDETTGLHLFETCPSGNVVEFNATAFGARCQSAKTYLERKIVNFSESDLNGLIY 190 Query: 633 LAIRAL 650 AI+AL Sbjct: 191 HAIKAL 196 >UniRef50_O23715 Cluster: Proteasome subunit alpha type-3; n=12; Magnoliophyta|Rep: Proteasome subunit alpha type-3 - Arabidopsis thaliana (Mouse-ear cress) Length = 249 Score = 103 bits (247), Expect = 4e-21 Identities = 59/186 (31%), Positives = 94/186 (50%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 ++T FSPDG + Q+EYA +AV T EK +K+ + R+I + Sbjct: 11 SVTTFSPDGRVFQIEYAAKAVDNSGTVVGIKCKDGIVMGVEKLIASKMMLPGSNRRIHSV 70 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 H MA AGL AD R ++ RA+ E +S++ D V ++ ++ +A T R Sbjct: 71 HRHAGMAVAGLAADGRQIVARAKSEARSYESVYGDAVPVKELSERVASYVHLCTLYWWLR 130 Query: 441 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATEN 620 PFG ++GG+D DG P L+ EPSGI Y + A G+ + + +EK E+ + Sbjct: 131 PFGCGVILGGYDRDG-PQLYMIEPSGISYRYFGAAIGKGKQAAKTEIEK-LNLSEMTCKE 188 Query: 621 GAVKLA 638 G +++A Sbjct: 189 GVIEVA 194 >UniRef50_A2E1I9 Cluster: Family T1, proteasome alpha subunit, threonine peptidase; n=1; Trichomonas vaginalis G3|Rep: Family T1, proteasome alpha subunit, threonine peptidase - Trichomonas vaginalis G3 Length = 233 Score = 103 bits (246), Expect = 5e-21 Identities = 62/188 (32%), Positives = 94/188 (50%) Frame = +3 Query: 87 TVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDD 266 T FSP+G +LQVE A +AV++G S ++ + KI +D Sbjct: 11 TTFSPEGRILQVENAMKAVQQGMPTVGLKSKTHAVIAGVMHSPSEFSSHQP--KIFKIDQ 68 Query: 267 HVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPF 446 H+ +A +GLTAD R L + EC H + + + +A QK T G+RP+ Sbjct: 69 HIGVAISGLTADGRGLCKFLRNECLHHTFCFGTEIRVADLADTVALQSQKKTSKVGKRPY 128 Query: 447 GISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENGA 626 G+ L+ G DG P LF+T PSG ++E+ A A GR A+ + +LE N T + Sbjct: 129 GVGLLMIGAGVDG-PRLFETCPSGQHWEYNAQAIGRRAQAAKTYLETNLNEFPDCTRDQL 187 Query: 627 VKLAIRAL 650 ++ A+RAL Sbjct: 188 IRHALRAL 195 >UniRef50_Q4P0X9 Cluster: Proteasome subunit alpha type; n=3; Fungi/Metazoa group|Rep: Proteasome subunit alpha type - Ustilago maydis (Smut fungus) Length = 305 Score = 103 bits (246), Expect = 5e-21 Identities = 57/182 (31%), Positives = 87/182 (47%), Gaps = 1/182 (0%) Frame = +3 Query: 84 ITVFSPDGHLLQVEYAQEAVRK-GSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 +T+FSPDG L QVEYA +A+ G T+ +KK KL + +V I L Sbjct: 10 LTIFSPDGRLYQVEYAFKAINTAGLTSIAVRGKDCSVVVGQKKVPDKLIDASSVTNIFNL 69 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 + G ADAR + RA++E K +T + + + +A + Q YTQ R Sbjct: 70 TPEIGCIMTGRVADARAQVQRAKMEAADFKYKYGYAITPDLLAKRMANMNQVYTQRAAMR 129 Query: 441 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATEN 620 P+G+S ++ G D + P +F+ +P+G Y ++A A G FLEK + T Sbjct: 130 PYGVSMILVGIDAERGPQIFKIDPAGYYVGFRATAAGVKQTEATNFLEKQFKKSSTTTTG 189 Query: 621 GA 626 A Sbjct: 190 DA 191 >UniRef50_Q7QYA1 Cluster: GLP_387_56144_56881; n=2; Giardia intestinalis|Rep: GLP_387_56144_56881 - Giardia lamblia ATCC 50803 Length = 245 Score = 102 bits (245), Expect = 7e-21 Identities = 61/195 (31%), Positives = 104/195 (53%), Gaps = 2/195 (1%) Frame = +3 Query: 90 VFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDDH 269 VFSPDG + Q+EYA ++V TA E+++ + L+ + +I +DDH Sbjct: 12 VFSPDGRIFQIEYALKSVTLSPTALAIRTHTGIVFAVERRTSSPLRLQTRFERIMHVDDH 71 Query: 270 VVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGR--RP 443 + AG +D+++L+ A+ E QSH+ ++ V L+ ++ ++ + + + + RP Sbjct: 72 AMACVAGHASDSKLLLQSARTEAQSHRFLYDEFVPLQALSESLSEVFINFGRGKKKLGRP 131 Query: 444 FGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENG 623 FG S LIGG D +P LF EPSG E A + G + T ++ L+ +Y D T + Sbjct: 132 FGCSLLIGGLD-GSTPRLFCAEPSGSVTEAMARSLGAGSTTAQQTLQDSYRDD--MTLDD 188 Query: 624 AVKLAIRALLEVVQS 668 A LA+ L +V++S Sbjct: 189 AKLLALEILRDVMES 203 >UniRef50_Q9VK14 Cluster: Proteasome subunit alpha type; n=2; Sophophora|Rep: Proteasome subunit alpha type - Drosophila melanogaster (Fruit fly) Length = 289 Score = 101 bits (243), Expect = 1e-20 Identities = 60/189 (31%), Positives = 98/189 (51%), Gaps = 1/189 (0%) Frame = +3 Query: 87 TVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTV-RKICLLD 263 T +SP G L QVEYA EAV++G+ ++ ++ T+ RKI +D Sbjct: 11 TTWSPQGRLFQVEYAMEAVKQGAATVGLKGTDYAVLAALCRTS---KDTNTLQRKIMPVD 67 Query: 264 DHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRP 443 DHV M+ AGLTADAR++ + EC +++ + + + + Q TQ RRP Sbjct: 68 DHVGMSIAGLTADARVVCQYMRTECMAYRHSYNAEFPVRRLVSNLGNKLQTTTQRYDRRP 127 Query: 444 FGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENG 623 +G+ L+ G+D G PH++Q P+ KA A G +++ R +LE+N + E + Sbjct: 128 YGVGLLVAGYDEQG-PHIYQVMPTANVLNCKAMAIGSRSQSARTYLERNMESFEDCDMDE 186 Query: 624 AVKLAIRAL 650 + AI+A+ Sbjct: 187 LICHAIQAI 195 >UniRef50_Q6CBM3 Cluster: Yarrowia lipolytica chromosome C of strain CLIB122 of Yarrowia lipolytica; n=6; Ascomycota|Rep: Yarrowia lipolytica chromosome C of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 289 Score = 101 bits (243), Expect = 1e-20 Identities = 57/167 (34%), Positives = 89/167 (53%) Frame = +3 Query: 93 FSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDDHV 272 +SP G L QVEYA EA+++GS K++ +L + +KI +D+H+ Sbjct: 12 YSPTGRLFQVEYALEAIKQGSAVVGLVSKTHAVVVALKRNAEELGSYQ--KKIIKVDNHL 69 Query: 273 VMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFGI 452 +A AGL DAR+L N + + S ++ + P+ + IA Q TQ GRRP+G+ Sbjct: 70 GVALAGLAPDARVLSNFLRQQAMSSQMVYKRPLAVSRAVYAIADKAQGNTQQYGRRPYGV 129 Query: 453 SCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 593 LI G D + PHL++ PSG E++ A G ++ R +LEK + Sbjct: 130 GLLIIGHD-EAGPHLYEFLPSGSALEYRGAAIGARSQAARTYLEKKF 175 >UniRef50_Q22WB3 Cluster: Proteasome A-type and B-type family protein; n=5; Oligohymenophorea|Rep: Proteasome A-type and B-type family protein - Tetrahymena thermophila SB210 Length = 267 Score = 100 bits (239), Expect = 4e-20 Identities = 57/168 (33%), Positives = 90/168 (53%) Frame = +3 Query: 87 TVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDD 266 + +S +G LLQV+YA +A+ +GS +K+S +KL + KI +DD Sbjct: 28 STWSTNGKLLQVDYATKAIDQGSITIGLRSQKFAVLVAQKRSNSKLSGYQ--EKIFQVDD 85 Query: 267 HVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPF 446 + M AG+TADAR++ + EC +HK + + I+ Q TQ+ G+RP+ Sbjct: 86 KIGMGVAGITADARVICKYMRTECLNHKYVYGSQHPAQRLVIKISEKSQHKTQTYGKRPY 145 Query: 447 GISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKN 590 G+ LI + DG P LFQT PSG +YE+ + G ++ + +LE N Sbjct: 146 GVGTLIIAQESDG-PKLFQTLPSGDFYEFYGQSIGSRSQAAKTYLENN 192 >UniRef50_Q8SRJ0 Cluster: 26S PROTEASOME SUBUNIT ALPHA-4; n=1; Encephalitozoon cuniculi|Rep: 26S PROTEASOME SUBUNIT ALPHA-4 - Encephalitozoon cuniculi Length = 224 Score = 100 bits (239), Expect = 4e-20 Identities = 62/195 (31%), Positives = 101/195 (51%) Frame = +3 Query: 84 ITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLD 263 + VFSPDG L+QVEYAQ+A +GS E+KS +L E Sbjct: 7 LAVFSPDGRLIQVEYAQQASEQGSLVVFGVDSEKISVSIERKSGNRLLLEEEKLFPISES 66 Query: 264 DHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRP 443 + M+++G DA +++N A++ C S+K + + + ++ + R ++ KQ+YT +RP Sbjct: 67 QKIWMSYSGFKPDAYLVMNVARMICFSYKNSTGEDIAIDQLARMLSEYKQRYTVVYHQRP 126 Query: 444 FGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENG 623 FG+ ++ F + P + EP G + E+ A G+ ++ V E+LEK D Sbjct: 127 FGVRTVL--FGLEPRPVAYVLEPDGNFSEFFCGAIGQKSQKVCEYLEKGEKGD------- 177 Query: 624 AVKLAIRALLEVVQS 668 V+L I L+EVVQS Sbjct: 178 LVRLTILGLMEVVQS 192 >UniRef50_P60900 Cluster: Proteasome subunit alpha type-6; n=69; Eukaryota|Rep: Proteasome subunit alpha type-6 - Homo sapiens (Human) Length = 246 Score = 99.1 bits (236), Expect = 8e-20 Identities = 59/194 (30%), Positives = 95/194 (48%), Gaps = 1/194 (0%) Frame = +3 Query: 84 ITVFSPDGHLLQVEYAQEAVRKGS-TAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 IT+FSP+G L QVEYA +A+ +G T+ +KK KL + TV + + Sbjct: 13 ITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKI 72 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 +++ G+TAD+R + RA+ E + K + ++ + + IA + Q YTQ+ R Sbjct: 73 TENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMR 132 Query: 441 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATEN 620 P G ++ G D + P +++ +P+G Y +KA A G FLEK T Sbjct: 133 PLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFE 192 Query: 621 GAVKLAIRALLEVV 662 V+ AI L V+ Sbjct: 193 QTVETAITCLSTVL 206 >UniRef50_UPI0000498A1A Cluster: proteasome alpha subunit; n=2; Entamoeba histolytica HM-1:IMSS|Rep: proteasome alpha subunit - Entamoeba histolytica HM-1:IMSS Length = 247 Score = 97.9 bits (233), Expect = 2e-19 Identities = 61/183 (33%), Positives = 89/183 (48%) Frame = +3 Query: 87 TVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDD 266 T FSPDG + Q++YA +AV +TA EK ++K+ E+ + ++I + Sbjct: 13 TTFSPDGKVFQIDYATKAVENSATALSIKCIDGVVFGVEKLIISKMIEKSSNKRIFNVGT 72 Query: 267 HVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPF 446 HV + AG DAR L+ +A E +S K + ++ + IA Q +T RPF Sbjct: 73 HVGITCAGFLPDARKLVKKANEEAESFKENYGMNIPVKVLAEKIAMYMQNHTLYGSLRPF 132 Query: 447 GISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENGA 626 G S LIGG D G L EPSG Y + AN G+ + + LEK ++ E Sbjct: 133 GCSLLIGGVDQHGY-SLHYIEPSGTTYGYFANGIGKGKQICKNELEK-INFSQITCEEAL 190 Query: 627 VKL 635 VKL Sbjct: 191 VKL 193 >UniRef50_A2FJV7 Cluster: Family T1, proteasome alpha subunit, threonine peptidase; n=1; Trichomonas vaginalis G3|Rep: Family T1, proteasome alpha subunit, threonine peptidase - Trichomonas vaginalis G3 Length = 232 Score = 97.5 bits (232), Expect = 3e-19 Identities = 59/192 (30%), Positives = 98/192 (51%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 ++T FS G L Q+E A +AV G E K + L E+ T K+ + Sbjct: 7 SLTTFSSGGKLNQIESALKAVSLGGQCVGVKAKNGAVIACESKPSSPLVEKVTNLKVQKI 66 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 +D+V + ++G+ D +++ + + L + + + ++ A Q YTQ G R Sbjct: 67 NDNVGIVYSGVNTDFHVILKSLRKASIKYSLRLGVEMPTREVVKHAAHKMQYYTQIGGVR 126 Query: 441 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATEN 620 PFG+S LI G++ G P L+Q +PSG ++ WKA A G+ + R FLE+ Y+ D+ + + Sbjct: 127 PFGVSLLIIGWEELG-PTLWQVDPSGTFWAWKATALGKRSDGSRTFLERRYSEDQ--SVD 183 Query: 621 GAVKLAIRALLE 656 A+ AI L E Sbjct: 184 DAIHTAISTLKE 195 >UniRef50_Q27563 Cluster: Proteasome subunit alpha type-3; n=11; Eukaryota|Rep: Proteasome subunit alpha type-3 - Dictyostelium discoideum (Slime mold) Length = 248 Score = 97.1 bits (231), Expect = 3e-19 Identities = 61/192 (31%), Positives = 94/192 (48%) Frame = +3 Query: 84 ITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLD 263 ++ +SPDG L QV+YA +AV T EK +K+ + R++ +D Sbjct: 12 VSTYSPDGKLFQVDYANKAVENSGTLVAIKAKDGVVLGVEKLVPSKMLCSGSNRRVHHID 71 Query: 264 DHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRP 443 HV +A AG ADAR LI RA+ E +++K T P+ ++ +++ IA +T RP Sbjct: 72 THVGVAIAGFLADARQLITRARSEAKNYKSTYGQPIPIKVLSQRIASYNHMHTLYGSVRP 131 Query: 444 FGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENG 623 FG S I G D G P LF EPSG + + G+ + + LE+ ++ E Sbjct: 132 FGCSIAITGIDQYG-PQLFLVEPSGSCVGYFGASLGKGKQAAKNELEEIRFSEMTCRE-- 188 Query: 624 AVKLAIRALLEV 659 A+K R + V Sbjct: 189 AIKEVSRIIYSV 200 >UniRef50_Q751N3 Cluster: AGL336Wp; n=7; Ascomycota|Rep: AGL336Wp - Ashbya gossypii (Yeast) (Eremothecium gossypii) Length = 306 Score = 95.9 bits (228), Expect = 8e-19 Identities = 58/187 (31%), Positives = 95/187 (50%), Gaps = 1/187 (0%) Frame = +3 Query: 93 FSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDDHV 272 FSP G L QVEYA EA+++GS K++ +L + +KI DDH+ Sbjct: 86 FSPTGRLFQVEYALEAIKQGSATVGLRSNKYVVLVALKRNADELSSYQ--KKIIKCDDHM 143 Query: 273 VMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFGI 452 ++ AGL DAR+L N + +C +L +++ + ++ QK TQS G RP+G+ Sbjct: 144 GLSLAGLAPDARVLSNFLRQQCNYSQLVYARDLSVVKAGQLLSDKAQKNTQSYGGRPYGV 203 Query: 453 SCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTAD-EVATENGAV 629 L+ G+D G+ HL + +PSG E A G ++ + +LE+ E+ + + Sbjct: 204 GLLLAGYDNSGA-HLLEFQPSGNTLELYGAAIGARSQGAKTYLERVMEEYLEIEDADALI 262 Query: 630 KLAIRAL 650 K + AL Sbjct: 263 KHGVEAL 269 >UniRef50_Q0MYX3 Cluster: Proteasome subunit alpha type; n=3; Eukaryota|Rep: Proteasome subunit alpha type - Emiliania huxleyi Length = 264 Score = 95.5 bits (227), Expect = 1e-18 Identities = 59/205 (28%), Positives = 96/205 (46%), Gaps = 12/205 (5%) Frame = +3 Query: 84 ITVFSPDGHLLQVEYAQEAVR-KGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 IT+FSP+G L QVEYA +A++ G T+ ++K KL + +V + + Sbjct: 13 ITIFSPEGRLYQVEYAFKAIKTSGLTSVGVRGADPCVVLTQRKVPDKLYDPESVTNMYAI 72 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 ++ + G+ DAR + + + E K + + Y+ + A Q YTQ R Sbjct: 73 TPNIGLVMTGIVPDARASVKKLREEAAKFKFNNGYDIPVSYLAKRAADTAQVYTQHANMR 132 Query: 441 PFGISCLIGGFDYDGS---PHLFQTEPSGIYYEWKANATGRSAKTVREFLEK-------- 587 P GI+ +I G D +G P LF+ +P+G Y +KA + G + FLEK Sbjct: 133 PLGIAMIIIGIDVEGEKKVPQLFRCDPAGYYVGYKATSAGAKEQEANNFLEKRFKPPAGS 192 Query: 588 NYTADEVATENGAVKLAIRALLEVV 662 N D + + V+LA+ L V+ Sbjct: 193 NVAVDPKLSHDDTVQLALACLQNVL 217 >UniRef50_A4UHA5 Cluster: Proteasome subunit alpha type; n=8; Eukaryota|Rep: Proteasome subunit alpha type - Alexandrium fundyense (Dinoflagellate) Length = 254 Score = 95.1 bits (226), Expect = 1e-18 Identities = 52/170 (30%), Positives = 86/170 (50%), Gaps = 1/170 (0%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 ++T FSPDG + QVEYAQ+AV T EK ++K+ + T ++I + Sbjct: 11 SVTTFSPDGRVFQVEYAQKAVENSGTTVAICCKDGVIFAVEKFLLSKMLVQGTNKRIFPV 70 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 H M+ AG +AD+R ++ RA+ E +K + + + E + + YT R Sbjct: 71 HRHAGMSIAGFSADSRQIVARARSEAHQYKNSYNEEIPPELLAERLGLFVHAYTLYWSIR 130 Query: 441 PFGISCLIGGFDYD-GSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 587 PFG S L+G D D P LF +P+G+ +++ A G+ + + +EK Sbjct: 131 PFGCSVLLGCVDQDTKKPSLFCVDPAGMVFKYSGTAIGKGKQAAKTEIEK 180 >UniRef50_Q5CUM6 Cluster: Proteasome subunit alpha type; n=2; Cryptosporidium|Rep: Proteasome subunit alpha type - Cryptosporidium parvum Iowa II Length = 251 Score = 93.9 bits (223), Expect = 3e-18 Identities = 54/197 (27%), Positives = 94/197 (47%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 +++ FSPDG + QVEYA +AV T +K +K+ T R++ + Sbjct: 11 SVSTFSPDGRVFQVEYANKAVDNSGTTIAMIYNSGIVFAVDKYVASKMMVAGTNRRVFAI 70 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 D+ + AG D+ +++ A+ E +++ +P+ + + IA +T R Sbjct: 71 DNQIGCCVAGFVTDSNKIVSIARSESLNYQKIYGNPIPIRVLAERIAMYMHNFTLYGSVR 130 Query: 441 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATEN 620 PFG S L+GG D D L+ PSG Y++ A A G+ + R LEK ++ +E Sbjct: 131 PFGCSILLGGLDQDRGVELYCIHPSGSCYKYCAMAVGKGRQFARTDLEK--LMEKNLSEE 188 Query: 621 GAVKLAIRALLEVVQSG 671 A+ A R +++ + G Sbjct: 189 DALYEAARVIIQSREEG 205 >UniRef50_A6R382 Cluster: Proteasome component C1; n=3; Pezizomycotina|Rep: Proteasome component C1 - Ajellomyces capsulatus NAm1 Length = 426 Score = 91.9 bits (218), Expect = 1e-17 Identities = 62/214 (28%), Positives = 99/214 (46%), Gaps = 26/214 (12%) Frame = +3 Query: 87 TVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDD 266 ++FSPDG QVEYA +AV G T+ EK +KL + ++I +D Sbjct: 142 SIFSPDGRNFQVEYAVKAVENGGTSIGIRCKDGVVLAVEKIISSKLLKPGANKRIATVDR 201 Query: 267 HVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPF 446 H+ + +GL D R ++RA+ E + ++T + P++ + + G Q YT + RPF Sbjct: 202 HIGIVSSGLLPDGRHFVSRARDEADNWRITYKGPISTHVLASRLGGYAQAYTLYSSVRPF 261 Query: 447 GISCLIGGFDYD--------------------------GSPHLFQTEPSGIYYEWKANAT 548 G++ +IGG+D + G P L+ EPSG+Y+ + AT Sbjct: 262 GVTSIIGGWDSELELPVDGEVGAGPKSGAGGKVASAKAGGPGLYMIEPSGLYWGYYGAAT 321 Query: 549 GRSAKTVREFLEKNYTADEVATENGAVKLAIRAL 650 G+ + + LEK A T VK A R + Sbjct: 322 GKGRQAAKAELEKLDLASGNFTLLQGVKEAARII 355 >UniRef50_Q7QUL1 Cluster: GLP_436_20835_20083; n=2; Giardia intestinalis|Rep: GLP_436_20835_20083 - Giardia lamblia ATCC 50803 Length = 250 Score = 91.5 bits (217), Expect = 2e-17 Identities = 62/206 (30%), Positives = 100/206 (48%), Gaps = 12/206 (5%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 ++T FSP GHL Q+ YA AV G + K + L + T+ + + Sbjct: 9 SLTTFSPSGHLRQITYALAAVDGGRLSIGIKCANGVVLMCHKAAENPLVDYPTISLVDNV 68 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 + + ++G +AD R L+N + + + ++ + + + R IA Q+YTQ G R Sbjct: 69 SPSLGITYSGFSADFRNLLNLGRKSYEQYWNEFQESMPVNMLARDIASTMQEYTQRGGVR 128 Query: 441 PFGISCLIGG--------FDYDGS---PH-LFQTEPSGIYYEWKANATGRSAKTVREFLE 584 PFG S L+ G + +GS P+ L+Q + SG YY WKA A G + R+FLE Sbjct: 129 PFGCSVLLAGKSMATEHETEANGSRINPYILYQVDSSGSYYTWKACANGNQSSQARDFLE 188 Query: 585 KNYTADEVATENGAVKLAIRALLEVV 662 K Y + V+ +G + + + L E V Sbjct: 189 KRYN-ESVSISDG-ILIGLTCLHEYV 212 >UniRef50_A0CDQ2 Cluster: Chromosome undetermined scaffold_17, whole genome shotgun sequence; n=3; Eukaryota|Rep: Chromosome undetermined scaffold_17, whole genome shotgun sequence - Paramecium tetraurelia Length = 245 Score = 89.8 bits (213), Expect = 5e-17 Identities = 56/194 (28%), Positives = 97/194 (50%), Gaps = 1/194 (0%) Frame = +3 Query: 84 ITVFSPDGHLLQVEYAQEAVR-KGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 IT+FSP+G L QVEYA +AV+ G T+ EK+ KL +E++V + + Sbjct: 12 ITLFSPEGRLYQVEYAFKAVKTSGLTSIGVKGTDTVCLITEKRVPDKLIDEKSVTNLFNV 71 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 + + G+ +DAR L+ R + E +L ++ +++ +A L Q TQ R Sbjct: 72 SEKIGALTTGIPSDARALVTRMRYEAGEFRLKNGYYCPVDVLSKRMADLAQTNTQYYQMR 131 Query: 441 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATEN 620 +G+ ++ +D + P L++ +PSG Y +KA A+G + +LEK + Sbjct: 132 SYGVETILCQYDDELGPLLYKLDPSGHYSGYKATASGVKEQEAINYLEKQIKKKADLNYD 191 Query: 621 GAVKLAIRALLEVV 662 + LAI+ L V+ Sbjct: 192 ETIMLAIQTLQNVI 205 >UniRef50_A5E6Y2 Cluster: Proteasome component Y7; n=4; Saccharomycetales|Rep: Proteasome component Y7 - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 178 Score = 89.0 bits (211), Expect = 9e-17 Identities = 48/131 (36%), Positives = 82/131 (62%), Gaps = 2/131 (1%) Frame = +3 Query: 276 MAFAGLTADARILINRAQIECQS-HKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFGI 452 M ++G+ D R+L+++A+ Q+ +KL + + + + IA + Q+ TQS G RPFG+ Sbjct: 1 MTYSGMGPDFRVLVDKARKLAQTNYKLIYNEYPPVRIMVQEIAKVMQESTQSGGIRPFGV 60 Query: 453 SCLIGGFD-YDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENGAV 629 S L+GG+D Y L+Q +PSG Y+ WKA A G+++ + + FLEK + + + E+ A+ Sbjct: 61 SLLVGGYDEYLDKFQLYQVDPSGSYFPWKATAIGKTSNSAKTFLEKRWN-ENLQLED-AI 118 Query: 630 KLAIRALLEVV 662 +A+ AL E V Sbjct: 119 HVALLALKESV 129 >UniRef50_A4RHU7 Cluster: Proteasome subunit alpha type; n=16; Fungi/Metazoa group|Rep: Proteasome subunit alpha type - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 283 Score = 86.2 bits (204), Expect = 6e-16 Identities = 47/138 (34%), Positives = 78/138 (56%), Gaps = 1/138 (0%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 ++T FSP G L+Q+EYA AV +G TA EKKS + L + ++ KI L+ Sbjct: 8 SLTTFSPSGKLVQIEYALNAVNQGVTALGIKATNGIVLATEKKSSSPLTDPSSLSKISLV 67 Query: 261 DDHVVMAFAGLTADARILINRA-QIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGR 437 ++ M +AG+ D R+L+++A ++ +K + + + +A + Q+ TQS G Sbjct: 68 TPNIGMVYAGMGPDYRVLVDKARKVSHSGYKRIYNEYPPTRILVQDVARVVQEATQSGGV 127 Query: 438 RPFGISCLIGGFDYDGSP 491 RP+G+S LI G+D +G P Sbjct: 128 RPYGVSLLIAGWD-EGIP 144 Score = 56.4 bits (130), Expect = 6e-07 Identities = 31/72 (43%), Positives = 41/72 (56%) Frame = +3 Query: 450 ISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENGAV 629 IS GG G P L+Q +PSG Y+ WKA A G+SA + + FLEK YT E AV Sbjct: 166 ISGKTGGI-LKGGPMLYQVDPSGSYFPWKATAIGKSAASAKTFLEKRYT--EGLELEDAV 222 Query: 630 KLAIRALLEVVQ 665 +A+ L E ++ Sbjct: 223 HIALLTLKETIE 234 >UniRef50_O17586 Cluster: Proteasome subunit alpha type-6; n=9; Bilateria|Rep: Proteasome subunit alpha type-6 - Caenorhabditis elegans Length = 246 Score = 85.8 bits (203), Expect = 8e-16 Identities = 57/190 (30%), Positives = 85/190 (44%), Gaps = 1/190 (0%) Frame = +3 Query: 84 ITVFSPDGHLLQVEYAQEAVRKGS-TAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 IT+FSP+G + QVEYA +A+ + TA +K+ L TV + + Sbjct: 13 ITIFSPEGRVYQVEYAFKAINSTNLTAVAVKGADAAVIAVQKRVPDSLIVADTVTSVYQI 72 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 V G+ DA+ I RAQ E S K + E + + +A L Q YTQ+ R Sbjct: 73 SQSVGCCAIGMIPDAKFQIKRAQGEAASWKYKNGYDMPCELLAKKMADLNQYYTQNAEMR 132 Query: 441 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATEN 620 G + L +D + P +++ +P+G Y K + G FLEK T Sbjct: 133 SLGCALLFISYDDEKGPEVYRVDPAGYYRGMKGVSVGVKQLPATSFLEKKIKKKSELTST 192 Query: 621 GAVKLAIRAL 650 A++LAI AL Sbjct: 193 EAIELAIEAL 202 >UniRef50_Q0CFX9 Cluster: Proteasome subunit alpha type; n=12; Pezizomycotina|Rep: Proteasome subunit alpha type - Aspergillus terreus (strain NIH 2624) Length = 311 Score = 84.2 bits (199), Expect = 3e-15 Identities = 45/130 (34%), Positives = 68/130 (52%) Frame = +3 Query: 87 TVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDD 266 +VFSPDG QVEYA +AV G TA EK +KL + ++I +D Sbjct: 13 SVFSPDGRNFQVEYAVKAVENGGTAIGIRCKDGVVLAVEKIITSKLLKPGANKRIATVDR 72 Query: 267 HVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPF 446 HV + +GL D R ++RA+ E S + + P+ + ++ + Q YT + RPF Sbjct: 73 HVGIVSSGLVPDGRHFVSRARDEASSWRGVYKSPIPVSALSNRLGSYVQAYTLYSSVRPF 132 Query: 447 GISCLIGGFD 476 GI+ +IGG+D Sbjct: 133 GITAIIGGWD 142 >UniRef50_A0CF33 Cluster: Chromosome undetermined scaffold_174, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_174, whole genome shotgun sequence - Paramecium tetraurelia Length = 249 Score = 83.8 bits (198), Expect = 3e-15 Identities = 48/172 (27%), Positives = 79/172 (45%), Gaps = 1/172 (0%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 ++ +S +G + QVEYA +AV T EK+ ++L E+ T ++I + Sbjct: 9 SVATYSQEGRIYQVEYATKAVENSETVIGVKCKDGVILAGEKQKFSRLLEDNTNKRIYNI 68 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 D MA G D R ++ RA+ E ++ PV+ ++ +A YT +G R Sbjct: 69 DTQTGMAICGKLPDGRNILQRAKAESSQYQDMYAIPVSANVLSDRVAQYVHAYTMYSGAR 128 Query: 441 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVR-EFLEKNY 593 PFG + I ++ LF EPSG Y + A G+ + EF +N+ Sbjct: 129 PFGSATFIASYNTFDGYELFMIEPSGNKYAYHACTHGKGRAVCKSEFERRNF 180 >UniRef50_A0NHA5 Cluster: Proteasome subunit alpha type; n=1; Anopheles gambiae str. PEST|Rep: Proteasome subunit alpha type - Anopheles gambiae str. PEST Length = 278 Score = 82.6 bits (195), Expect = 8e-15 Identities = 48/189 (25%), Positives = 83/189 (43%), Gaps = 1/189 (0%) Frame = +3 Query: 93 FSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDDHV 272 FSPDG + Q+EYA +AV T EK +KL E +I +D + Sbjct: 15 FSPDGRVFQIEYAAKAVENSGTVIGLRGKDGVVLAVEKLITSKLYEPDCGTRIFTIDTSI 74 Query: 273 VMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFGI 452 MA +G+ D R +++ A+ E S++ P+ L+ + ++ YT + RPFG+ Sbjct: 75 GMAISGMITDGRAVVDIARQEAASYRQQNNRPIPLKQLNDRLSSYFHAYTLYSAVRPFGV 134 Query: 453 SCLIGGFDYDGSPHLFQTEPSGI-YYEWKANATGRSAKTVREFLEKNYTADEVATENGAV 629 S ++ + + P ++ +PSG+ TG S+ T+ + Y G Sbjct: 135 SVILASWSEEKGPEMYMIDPSGVSCVSLSQKQTGESSTTLATIVMYYYFQGYFGCAVGKA 194 Query: 630 KLAIRALLE 656 K + +E Sbjct: 195 KQTAKTEIE 203 >UniRef50_UPI0000499E10 Cluster: proteasome alpha subunit; n=1; Entamoeba histolytica HM-1:IMSS|Rep: proteasome alpha subunit - Entamoeba histolytica HM-1:IMSS Length = 242 Score = 80.6 bits (190), Expect = 3e-14 Identities = 54/196 (27%), Positives = 89/196 (45%), Gaps = 1/196 (0%) Frame = +3 Query: 84 ITVFSPDGHLLQVEYAQEAVRKGS-TAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 +T+FSP+G L QVEYA +A + S T +KK +L + TV + + Sbjct: 10 LTIFSPEGRLYQVEYALKATKCESLTTVGVCSDEAACIITQKKLPDRLVDPSTVTHLHRI 69 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 HV +G+ AD +++ R+Q +L + + + + A Q TQ R Sbjct: 70 SKHVGCCMSGIYADGKVIAQRSQYYASKFQLDYGYEMPVSLVAKKTADFAQMLTQHAYMR 129 Query: 441 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATEN 620 PFG+S + G+D P L++++P+G ++ A G + LEK E+ T + Sbjct: 130 PFGVSSMFIGWDEVSGPQLWRSDPAGSVAAFRGCAAGEKEQEAFNNLEKKKITKEL-TVD 188 Query: 621 GAVKLAIRALLEVVQS 668 V A+ L V S Sbjct: 189 QVVCQALDCLQTVTSS 204 >UniRef50_Q94II8 Cluster: Proteasome subunit alpha type; n=3; Oryza sativa|Rep: Proteasome subunit alpha type - Oryza sativa subsp. japonica (Rice) Length = 253 Score = 79.8 bits (188), Expect = 6e-14 Identities = 52/195 (26%), Positives = 88/195 (45%), Gaps = 4/195 (2%) Frame = +3 Query: 84 ITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLD 263 IT+FSP+G L Q++YA AV+ + KL + T+ + + Sbjct: 27 ITLFSPEGRLCQLDYAFNAVKLAGITSVGVRGDDSVYVLTHRKEDKLHDPTTITNLFAIT 86 Query: 264 DHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRP 443 D + + G+ D R + A+ + ++ + ++IA Q TQ RP Sbjct: 87 DRIGLLATGMPGDGRAIAQEARNAAAEFRFKWGYKMSPCMLAQWIADRAQIRTQHAQIRP 146 Query: 444 FGISCLIGGFDYD-GSPHLFQTEPSGIYYEWKANATGRSAKTVREFLE---KNYTADEVA 611 +G+ +I G D + G+P LF +P+G ++ KA + G K V FLE K+ + Sbjct: 147 YGVVSMIFGIDEEKGTPELFTCDPAGQFFAHKATSAGPKEKEVMNFLEERMKSKPSLSSG 206 Query: 612 TENGAVKLAIRALLE 656 T G K A++ +LE Sbjct: 207 TTKGLAKSALKHVLE 221 >UniRef50_A5K7Q6 Cluster: 20S proteasome alpha subunit G, putative; n=6; Plasmodium|Rep: 20S proteasome alpha subunit G, putative - Plasmodium vivax Length = 253 Score = 78.6 bits (185), Expect = 1e-13 Identities = 45/174 (25%), Positives = 85/174 (48%), Gaps = 3/174 (1%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAK--LQEERTVRKIC 254 +++ FSPDG L QVEY +A+ +TA ++ K + + + +I Sbjct: 11 SVSTFSPDGRLYQVEYIYKAINSNNTALSLECKDGLLTCCVNSNLLKNKMIKHSSYSRIH 70 Query: 255 LLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNG 434 ++++V++ +AGL DAR +I+RA+ E S+ L + L + ++ +T Sbjct: 71 HINNNVIVTYAGLDGDARNIIDRAKYEANSYYLNFHTNIPLHILANRVSLYLHSFTLYWH 130 Query: 435 RRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK-NY 593 RPF S ++ FD ++ EP+G Y++ G++ + + +EK NY Sbjct: 131 LRPFASSIILASFDEKEKGEIYCVEPNGACYKYSGVVIGKNKEMFKTEIEKRNY 184 >UniRef50_Q8SR59 Cluster: PROTEASOME ALPHA SUBUNIT C6; n=1; Encephalitozoon cuniculi|Rep: PROTEASOME ALPHA SUBUNIT C6 - Encephalitozoon cuniculi Length = 234 Score = 78.2 bits (184), Expect = 2e-13 Identities = 54/191 (28%), Positives = 85/191 (44%) Frame = +3 Query: 90 VFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDDH 269 +F+ DG LLQ+EY EAV G +K KL+E + + Sbjct: 10 IFNSDGKLLQIEYGLEAVNNGLPVVTAKSKDMIVCVSKKIPQDKLEESEAT-SFHRVSEK 68 Query: 270 VVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFG 449 +A GL D ++ R ++ + VT + + R A Q+ QS+ R Sbjct: 69 CYVAITGLPGDTDYVVKRIKMVANRKAFSFGFEVTPDILCRSFADKVQQLIQSSAERSAA 128 Query: 450 ISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENGAV 629 + I GFD + P ++QT+ SGI Y A A G + +F+EKNY +D + Sbjct: 129 FNASIFGFDKE-RPMIYQTDMSGISYPCYATAAGEKHGKMTKFIEKNYRSD--IDDKELF 185 Query: 630 KLAIRALLEVV 662 ++A+ ALLE + Sbjct: 186 EVAVGALLESI 196 >UniRef50_Q9NDA3 Cluster: 20S proteasome alpha 7 subunit; n=1; Trypanosoma brucei|Rep: 20S proteasome alpha 7 subunit - Trypanosoma brucei Length = 237 Score = 77.0 bits (181), Expect = 4e-13 Identities = 48/166 (28%), Positives = 75/166 (45%) Frame = +3 Query: 90 VFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDDH 269 +FS DG + QVEYA +AV GSTA EK +++ EE + +I +D Sbjct: 12 IFSADGRVFQVEYACKAVDNGSTAVAACCKDGVVVAVEKILTSRMLEEGSNNRIHAVDRQ 71 Query: 270 VVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFG 449 + G+ D +++RA+ E ++ + P+ + I YT RPFG Sbjct: 72 AGICVCGVLPDGLAVVSRARGEAENSRDIFSTPILGSLLASRIGEFMHVYTTHYAYRPFG 131 Query: 450 ISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 587 S +I + DG P L+ +PSG + A G+ + LEK Sbjct: 132 CSVIIASYADDG-PQLYVADPSGAVAGYYGIALGKGKTVAKTELEK 176 >UniRef50_Q09583 Cluster: Proteasome subunit alpha type-3; n=2; Caenorhabditis|Rep: Proteasome subunit alpha type-3 - Caenorhabditis elegans Length = 250 Score = 76.2 bits (179), Expect = 7e-13 Identities = 57/193 (29%), Positives = 85/193 (44%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 A + FSPDG + QVEYAQ+AV T +K +KL + ++ + Sbjct: 11 AASTFSPDGRIFQVEYAQKAVDNAGTMIAIRGKNGVVVVADKLISSKLYTDNANPRMFNV 70 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 +D+V +A AG D L N A E +P+ ++ I +A +T R Sbjct: 71 NDNVGVAVAGNYPDGFALKNYAYGEAMKWLKDYREPMPIQNIANSVAEYIHIHTLGIS-R 129 Query: 441 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATEN 620 PFG ++ LF EPSG+ YE+KA A G+ + + +EK E N Sbjct: 130 PFGAGAFFMSWNKQTGGRLFLVEPSGLNYEYKAWAVGKHRQAAKAEIEK--LKIEELDVN 187 Query: 621 GAVKLAIRALLEV 659 VK A R ++ V Sbjct: 188 QLVKEAARIIMVV 200 >UniRef50_A4RSN5 Cluster: Proteasome subunit alpha type; n=2; Ostreococcus|Rep: Proteasome subunit alpha type - Ostreococcus lucimarinus CCE9901 Length = 236 Score = 75.8 bits (178), Expect = 9e-13 Identities = 53/188 (28%), Positives = 86/188 (45%) Frame = +3 Query: 93 FSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDDHV 272 +SP G L QVEYA EAV++GST K+ +KL + KI ++ V Sbjct: 13 WSPQGRLHQVEYAMEAVKQGSTVVACGNKKCAVLAALKRKQSKLSSMQ--EKIFAINTRV 70 Query: 273 VMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFGI 452 +A +GL+ D L+ + E + + + Q + + RP G+ Sbjct: 71 GVAVSGLSTDGAKLVKLLREESTREEFVYGRSACPGRLAAAASKSLQISMRKSSGRPCGV 130 Query: 453 SCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENGAVK 632 ++ G +FQT PSG ++ A G +++ R +LEKN A E A+ + + Sbjct: 131 GLVLVGSSEQLGCQIFQTCPSGEVHQMSCTAIGGRSQSARTYLEKNMEALETASVDEMIM 190 Query: 633 LAIRALLE 656 +A+RAL E Sbjct: 191 IALRALNE 198 >UniRef50_Q7QUP6 Cluster: GLP_47_22543_21776; n=2; Giardia intestinalis|Rep: GLP_47_22543_21776 - Giardia lamblia ATCC 50803 Length = 255 Score = 75.8 bits (178), Expect = 9e-13 Identities = 50/192 (26%), Positives = 88/192 (45%), Gaps = 3/192 (1%) Frame = +3 Query: 84 ITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLD 263 + FSP G L Q+ YA EA GS + ++ L + K+ +D Sbjct: 7 VATFSPTGKLNQITYAMEAPSFGSPSVGLASKDAVVLVAVRRQTTPLSSFQD--KLFEVD 64 Query: 264 DHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRP 443 H+ + +G+ ADA ++ + EC + + P + + +A Q TQ G RP Sbjct: 65 KHIGICISGIYADAYKMLRLLRDECTEYTYVYDTPHPVGPLVAKLAEDAQARTQFWGYRP 124 Query: 444 FGISCLIGGFDYDG---SPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVAT 614 +G S LIGG D +P L+ P+ ++ E++A + G ++T+ L+ + E A+ Sbjct: 125 YGASLLIGGIDTRNNKQTPRLYVLSPNAVFKEYRAVSLGMGSQTINTHLKSHVDEYENAS 184 Query: 615 ENGAVKLAIRAL 650 + LA+ +L Sbjct: 185 VERLIALALDSL 196 >UniRef50_Q00ZK2 Cluster: Proteasome subunit alpha type; n=2; Ostreococcus|Rep: Proteasome subunit alpha type - Ostreococcus tauri Length = 262 Score = 74.9 bits (176), Expect = 2e-12 Identities = 48/167 (28%), Positives = 76/167 (45%) Frame = +3 Query: 87 TVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDD 266 T +SPDG + QVEYA +AV G EK +KL + T R+ + Sbjct: 73 TTYSPDGRVFQVEYAGKAVDAGGLTVGVKCVDGVVIACEKLVPSKLHKPGTNRRTRAVAR 132 Query: 267 HVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPF 446 H + +G T D + +RA+ EC ++K D + + + +A +T RPF Sbjct: 133 HAGVGGSGYTPDLAAVADRARAECANYKSFYGDAIPGKVLAERMAHYYHLFTLYWSVRPF 192 Query: 447 GISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 587 G S L+G D+DG HL+ E +G + + G+ + +EK Sbjct: 193 GCSTLLGCKDFDGY-HLYLVEQNGECAKMRGACIGKGKNAAKTEVEK 238 >UniRef50_Q98RW3 Cluster: Similar to proteasome A-type submit; n=1; Guillardia theta|Rep: Similar to proteasome A-type submit - Guillardia theta (Cryptomonas phi) Length = 233 Score = 74.5 bits (175), Expect = 2e-12 Identities = 46/189 (24%), Positives = 98/189 (51%) Frame = +3 Query: 84 ITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLD 263 ++ F+ G + Q+EYA +AV + +T S K + K+ +++ Sbjct: 6 LSSFNSKGKISQIEYASKAVLQSNTVISVKGNNLLLTLTLDISNKKNIFTQIEPKVFIIN 65 Query: 264 DHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRP 443 +++++ +GL +D I+I++A+ C+ + ++ +++ ++ Q +T S+G RP Sbjct: 66 KYIILSASGLKSDIIIVISKARSICRDFQHKYGHQISTASLSKDLSSFLQNFTSSSGFRP 125 Query: 444 FGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENG 623 G+S I G D DG P LF+ SG + ++ G+S+K ++E++ + ++ + T+ Sbjct: 126 LGVSLNILGIDKDG-PELFEINTSGEINDVNFSSIGKSSKDIKEYIRARWCSN-LETKT- 182 Query: 624 AVKLAIRAL 650 +KL I L Sbjct: 183 LLKLVINCL 191 >UniRef50_Q8SRU7 Cluster: 26S PROTEASOME ALPHA-TYPE SUBUNIT C9; n=1; Encephalitozoon cuniculi|Rep: 26S PROTEASOME ALPHA-TYPE SUBUNIT C9 - Encephalitozoon cuniculi Length = 232 Score = 73.7 bits (173), Expect = 4e-12 Identities = 53/183 (28%), Positives = 81/183 (44%), Gaps = 2/183 (1%) Frame = +3 Query: 93 FSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDDHV 272 F+ +G L QVE+A + V + T V K + KI L D + Sbjct: 11 FTDEGRLPQVEFAIKNVSRAGTIIGYVCSDGVVLM----GVNKEPTNGPMEKIYQLSDSI 66 Query: 273 VMAFAGLTADARILINRAQIECQS--HKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPF 446 GL DA L A+I+ Q + VE P+T + +++ KQ +TQ G RPF Sbjct: 67 YCVLCGLFGDAMELKRYARIKAQEVLERFGVECPLTT--LCKFVGQRKQAFTQYAGTRPF 124 Query: 447 GISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENGA 626 G+S L G DG L T+PSG WK G + + + L+ ++ DE+ + Sbjct: 125 GVSFLYAGV-IDGKYALMSTDPSGTSNRWKGMCYGENEEAINRGLKNDFPEDEMDMKTAT 183 Query: 627 VKL 635 V++ Sbjct: 184 VEI 186 >UniRef50_UPI000150A654 Cluster: Proteasome A-type and B-type family protein; n=1; Tetrahymena thermophila SB210|Rep: Proteasome A-type and B-type family protein - Tetrahymena thermophila SB210 Length = 244 Score = 72.9 bits (171), Expect = 6e-12 Identities = 47/172 (27%), Positives = 79/172 (45%), Gaps = 1/172 (0%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 ++T F+ DG++ QVEYAQ+AV T EKK KL E + R+I + Sbjct: 5 SVTTFTQDGYIKQVEYAQKAVSDSETILGVRCKDGVILGAEKKLQTKLMVEDSDRRIYNI 64 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 ++ M G D R +++RA+ E Q ++ P++ ++ +T R Sbjct: 65 QKNIGMIVGGRIPDGRNVVHRARKEAQEYEKYFSMPISGRILSERTGQYLHAHTLYGAYR 124 Query: 441 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTV-REFLEKNY 593 PFG S +I +D L Q++ +G + A A G+ + V F +N+ Sbjct: 125 PFGCSVIISSYDPIDGLQLHQSDNAGYCLGYYACAQGQGKQEVMAHFGRRNF 176 >UniRef50_Q98S57 Cluster: 26S proteasome SU; n=1; Guillardia theta|Rep: 26S proteasome SU - Guillardia theta (Cryptomonas phi) Length = 232 Score = 72.1 bits (169), Expect = 1e-11 Identities = 44/169 (26%), Positives = 84/169 (49%), Gaps = 1/169 (0%) Frame = +3 Query: 90 VFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICL-LDD 266 ++S DG + Q+E+A E + K ++A +K+ K E+ + L+ Sbjct: 5 LYSHDGRVEQLEFALELIDKSNSAIGIIYEKGILFATMEKN--KHNSEKEYQNFTFALEK 62 Query: 267 HVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPF 446 +++ +G DA ++ + +KL ++ V +E I Y++ + K TQ +RP Sbjct: 63 NIICIASGNIPDANTILFYLKSFADEYKLMFQETVPIEKIVGYLSDIMHKPTQMIYQRPL 122 Query: 447 GISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 593 G+S +IGG+D LF+ +PSG + W+A + G + + +E+NY Sbjct: 123 GVSFIIGGWDEFRGFQLFKIDPSGNFSGWRATSIGFNNILNQTLIEENY 171 >UniRef50_Q98RV9 Cluster: 26S proteasome SU A5; n=1; Guillardia theta|Rep: 26S proteasome SU A5 - Guillardia theta (Cryptomonas phi) Length = 232 Score = 70.5 bits (165), Expect = 3e-11 Identities = 56/196 (28%), Positives = 90/196 (45%), Gaps = 5/196 (2%) Frame = +3 Query: 96 SPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDDHVV 275 SP+G L +EYAQEA GST+ E+K L + +KI +LD + Sbjct: 8 SPEGRLKDLEYAQEAANLGSTSCGIKTKDFIFILSERKKKKSL-DYLNDQKIYVLDKNKG 66 Query: 276 MAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN-----GRR 440 +GL +D+R +I+ +I C++ + ++E + I L Y +N R Sbjct: 67 CCVSGLISDSRKIIDNVRIYCENKYFLINSYPSIEECSNLINNLITSYNTNNDVNKISPR 126 Query: 441 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATEN 620 P G S L+ G + L + +PSG Y + K A G +K V L++ Y ++ E Sbjct: 127 PLGTSFLLFG-KSNKKLELIKVDPSGRYIKDKILAIGEGSKDVLIILQEGYRSNMKKIE- 184 Query: 621 GAVKLAIRALLEVVQS 668 A LA + L + +S Sbjct: 185 -AKTLAFKTLRAISES 199 >UniRef50_Q8SR95 Cluster: 20S PROTEASOME COMPONENT C3; n=1; Encephalitozoon cuniculi|Rep: 20S PROTEASOME COMPONENT C3 - Encephalitozoon cuniculi Length = 233 Score = 69.3 bits (162), Expect = 8e-11 Identities = 50/169 (29%), Positives = 78/169 (46%), Gaps = 1/169 (0%) Frame = +3 Query: 84 ITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLD 263 +T+FS +G L Q + A A GS + K V L VRK+ + Sbjct: 9 VTLFSSEGKLGQCDNALRAAVNGSLSIGASAADGAVLM-SFKDVPPLVIREEVRKVFKIC 67 Query: 264 DHVVMAFAGLTADARILIN-RAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 D + ++GL D RI +N QI + + + P ++ T + + + Q+YTQ +G R Sbjct: 68 DTIGCTYSGLQPDCRIQVNIGCQIAEEYYDVYGRYP-DVDVFTAHFSSVVQEYTQKSGYR 126 Query: 441 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 587 PFG + G G P L+Q +PSG Y A+G R+F+E+ Sbjct: 127 PFGTLMIFAG-PVRGVPRLYQVDPSGSYQTADVCASGVGYSDARKFVER 174 >UniRef50_Q5CUM9 Cluster: Proteasome subunit alpha1; n=3; Cryptosporidium|Rep: Proteasome subunit alpha1 - Cryptosporidium parvum Iowa II Length = 252 Score = 67.7 bits (158), Expect = 2e-10 Identities = 47/175 (26%), Positives = 75/175 (42%), Gaps = 7/175 (4%) Frame = +3 Query: 84 ITVFSPDGHLLQVEYAQEAVRKGS-TAXXXXXXXXXXXXXEKK------SVAKLQEERTV 242 IT+FSP+G L Q+EY AV+ + TA EKK KL + V Sbjct: 13 ITIFSPEGKLYQIEYTFRAVKNSNITAIAIKGKDTVCIVCEKKVPNQQGQQDKLLDPAYV 72 Query: 243 RKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYT 422 + + H+ GL D R +I++ + + + Y++ IA + Q YT Sbjct: 73 TSLYKVRKHIGAVMLGLAPDCRSIISKCREIAGKFAFEKGVEIPVSYLSHKIADVNQLYT 132 Query: 423 QSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 587 Q R G S + D + P L++ +P+G + ++A A G + LEK Sbjct: 133 QHASMRLLGASGMFISIDDEDGPSLYKIDPAGYFASYRACAVGTKEREGNNALEK 187 >UniRef50_Q7QSC8 Cluster: GLP_105_6759_5881; n=2; Giardia intestinalis|Rep: GLP_105_6759_5881 - Giardia lamblia ATCC 50803 Length = 292 Score = 64.9 bits (151), Expect = 2e-09 Identities = 50/186 (26%), Positives = 80/186 (43%), Gaps = 10/186 (5%) Frame = +3 Query: 93 FSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDDHV 272 +SPDG + QV+YA +AV + +K ++ + E + ++D + Sbjct: 35 YSPDGKIFQVDYALKAVEQHGLCVGIRTSGGVALAVQK-NIHDILEIDSAPCFYQIEDSI 93 Query: 273 VMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFGI 452 V+A AGL D +L+++A+ +S++ V + I+G Q YT RPFG Sbjct: 94 VIAVAGLQPDGMVLVSKAREVAESYRENYSRIVPTGVLANSISGYMQLYTHYGEVRPFGC 153 Query: 453 SCLIGGFDYDGSP----------HLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTAD 602 S LI G+D S L+ +PSG A A GR + LE + Sbjct: 154 SLLIAGYDSIASADEPTTLKTKYSLYLLQPSGDITNCFATAAGRHTSQAKVELENHMGPA 213 Query: 603 EVATEN 620 E T + Sbjct: 214 EKDTND 219 >UniRef50_Q9YER0 Cluster: Proteasome beta subunit; n=1; Aeropyrum pernix|Rep: Proteasome beta subunit - Aeropyrum pernix Length = 219 Score = 63.7 bits (148), Expect = 4e-09 Identities = 50/178 (28%), Positives = 84/178 (47%), Gaps = 1/178 (0%) Frame = +3 Query: 132 QEAVRKGSTAXXXXXXXXXXXXXEKKSVAK-LQEERTVRKICLLDDHVVMAFAGLTADAR 308 + VR G+T +K++ A L R V+KI +L ++V M +GL ADA+ Sbjct: 19 ERVVRSGTTTVGLIASDHVILAADKRATAGFLIASRRVKKIVMLSNYVAMTVSGLVADAQ 78 Query: 309 ILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFGISCLIGGFDYDGS 488 IL + + E + +++T + ++ R++A L S+ P+ + ++GG YD Sbjct: 79 ILSDVLREEIRLYEMTNK----VKPSVRFVASLLSNILFSSKFFPYIVQLIVGG--YDTQ 132 Query: 489 PHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENGAVKLAIRALLEVV 662 P L+ + G E K ATG + LE+ Y D E A+K+A A+ V Sbjct: 133 PRLYTLDLFGSITEDKYTATGSGSPIAYGVLEERYREDLSVEE--AIKVATTAIRSAV 188 >UniRef50_Q4N061 Cluster: Proteasome subunit alpha type 3, putative; n=3; Piroplasmida|Rep: Proteasome subunit alpha type 3, putative - Theileria parva Length = 267 Score = 61.7 bits (143), Expect = 2e-08 Identities = 50/189 (26%), Positives = 80/189 (42%), Gaps = 20/189 (10%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSV--------AKLQEER 236 +++ FSPDG + QVEYA +AV TA + + A + + + Sbjct: 11 SVSTFSPDGRVFQVEYATKAVDSAPTAVAAVFSDGIVFAADSLACGAQDDSPYANVLQAK 70 Query: 237 TVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQK 416 ++ +D+ + A AGL DA+ ++ RAQ EC+S + I +A Sbjct: 71 PAWRVFAVDERMGAAVAGLLPDAKCVVRRAQEECKSFLKEYGTKAPVRVIAERVALFVHA 130 Query: 417 YTQSNGRRPFGISCLIGGFDYDGSP------------HLFQTEPSGIYYEWKANATGRSA 560 YT RPFG+S L+ G + + S L+ E SG Y++ A G+ Sbjct: 131 YTLYWHVRPFGVSILLAGTNENNSRTTYSVLQLFTSYELYCIEGSGACYKYGGMAIGKGK 190 Query: 561 KTVREFLEK 587 + LEK Sbjct: 191 HIAKTELEK 199 >UniRef50_Q8TW10 Cluster: Protease subunit of the proteasome; n=2; Euryarchaeota|Rep: Protease subunit of the proteasome - Methanopyrus kandleri Length = 210 Score = 59.7 bits (138), Expect = 6e-08 Identities = 41/178 (23%), Positives = 87/178 (48%), Gaps = 1/178 (0%) Frame = +3 Query: 135 EAVRKGSTAXXXXXXXXXXXXXEKKSV-AKLQEERTVRKICLLDDHVVMAFAGLTADARI 311 + + KG+T ++++V L + V+KI + D++ + AG ADA+ Sbjct: 5 DQLTKGTTTVGILADKGVVLAADRRAVMGNLIAGKQVKKIFRIHDYIGVTTAGSVADAQK 64 Query: 312 LINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFGISCLIGGFDYDGSP 491 +++ + E + ++L ++ + I+ + ++ RP+ + ++GGF+ D P Sbjct: 65 IVDLMRAEARLYELRHNRMISARALANMISHVL--HSSLKAFRPYLVQLIVGGFN-DDDP 121 Query: 492 HLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENGAVKLAIRALLEVVQ 665 L+ +PSG E ATG + T LE Y +E + + A+++A+RA+ ++ Sbjct: 122 ALYNLDPSGSIIEEDYTATGSGSPTAYGVLEAEY--EEGMSLDDAIEVAVRAVKSALE 177 >UniRef50_Q7QW44 Cluster: GLP_457_25625_26368; n=2; Giardia intestinalis|Rep: GLP_457_25625_26368 - Giardia lamblia ATCC 50803 Length = 247 Score = 59.3 bits (137), Expect = 8e-08 Identities = 45/159 (28%), Positives = 72/159 (45%), Gaps = 2/159 (1%) Frame = +3 Query: 81 AITVFSPDGHLLQVEYAQEAVR-KGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICL 257 A+TVF+P+G L QVEYA AV+ G + + +S +L + I Sbjct: 10 ALTVFNPEGKLFQVEYAFRAVKTSGLSHVAIRCLDGVVLVSQLQSADRLVDTANNTFIHE 69 Query: 258 LDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGR 437 +++ G AD R +I+R + E T + + +A + Q YTQ + Sbjct: 70 INETSACMICGRIADGRRVIDRVRSEAVDFFRKWNYQPTADILCTRLADINQIYTQEAWQ 129 Query: 438 RPFGISCLIGGFDYDGSPH-LFQTEPSGIYYEWKANATG 551 RPFG + G+D + LF+T+P+G + A A G Sbjct: 130 RPFGNIAVFAGWDPEQDRSLLFKTDPAGTNTGYFAIAVG 168 >UniRef50_A3DN21 Cluster: 20S proteasome, A and B subunits; n=1; Staphylothermus marinus F1|Rep: 20S proteasome, A and B subunits - Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / F1) Length = 213 Score = 59.3 bits (137), Expect = 8e-08 Identities = 38/144 (26%), Positives = 69/144 (47%) Frame = +3 Query: 234 RTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQ 413 + RK+ + HV + FAGL DA+ +I ++E ++++L + + + + + ++ + Sbjct: 46 KNTRKVHPITKHVGIGFAGLVGDAQFIIRALRMEAENYELQLGREIRVRGLAKILSLILY 105 Query: 414 KYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 593 Y + P ++GGFD G P ++ +P G E K A G +EK Y Sbjct: 106 SYKLA----PLMTEVVVGGFDEKG-PQIYVLDPVGSLIEDKYVALGSGGPIALGIIEKEY 160 Query: 594 TADEVATENGAVKLAIRALLEVVQ 665 D E A KLA+ A+ E ++ Sbjct: 161 REDIDVDE--AEKLAVSAIREAIE 182 >UniRef50_Q9YES4 Cluster: Proteasome beta subunit; n=1; Aeropyrum pernix|Rep: Proteasome beta subunit - Aeropyrum pernix Length = 203 Score = 58.8 bits (136), Expect = 1e-07 Identities = 40/139 (28%), Positives = 62/139 (44%) Frame = +3 Query: 234 RTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQ 413 R +KI +++D + +AFAGL D L+ + + + L P T+ + ++++ L Sbjct: 34 RNFKKIFVINDRIGIAFAGLYGDMGGLVRIVEGQMRLASLETGKPATVRNVAKFLSSLLY 93 Query: 414 KYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 593 Y PF + ++GG D G P L+ +P G E A G A T LE Y Sbjct: 94 SYKFF----PFNVEAIVGGIDPGGEPKLYVLDPLGSIIEEDYVAAGTGATTAFGLLEHVY 149 Query: 594 TADEVATENGAVKLAIRAL 650 E A K A+ AL Sbjct: 150 KRGMSLEE--AKKAAVEAL 166 >UniRef50_Q3TEL1 Cluster: 2 days neonate thymus thymic cells cDNA, RIKEN full-length enriched library, clone:C920013M15 product:proteasome (prosome, macropain) subunit, alpha type 3, full insert sequence; n=13; Euteleostomi|Rep: 2 days neonate thymus thymic cells cDNA, RIKEN full-length enriched library, clone:C920013M15 product:proteasome (prosome, macropain) subunit, alpha type 3, full insert sequence - Mus musculus (Mouse) Length = 180 Score = 58.4 bits (135), Expect = 1e-07 Identities = 31/104 (29%), Positives = 54/104 (51%) Frame = +3 Query: 276 MAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFGIS 455 MA AGL ADAR L + A+ E + + + L+++ +A YT + RPFG S Sbjct: 1 MAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYSAVRPFGCS 60 Query: 456 CLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 587 ++G + + L+ +PSG+ Y + A G++ + + +EK Sbjct: 61 FMLGSYSANDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEK 104 >UniRef50_A2D8G5 Cluster: Family T1, proteasome alpha subunit, threonine peptidase; n=1; Trichomonas vaginalis G3|Rep: Family T1, proteasome alpha subunit, threonine peptidase - Trichomonas vaginalis G3 Length = 240 Score = 58.0 bits (134), Expect = 2e-07 Identities = 40/165 (24%), Positives = 69/165 (41%) Frame = +3 Query: 93 FSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDDHV 272 FSPDG QVEYA +AV K S A EK + L +I ++D + Sbjct: 15 FSPDGRQFQVEYATKAVEKDSLALGVKCKDGILLAAEKNLTSTLLTPGGNPRIFWINDSI 74 Query: 273 VMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFGI 452 A G D ++ +++ ++ +T+ + ++ RPFG Sbjct: 75 ACATIGHRPDCYSIVEQSRNRAETFTSNFGIKITVPQLASEVSQQFHLAHYYQAYRPFGC 134 Query: 453 SCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 587 + + + D L+ EPSG +Y + A+ G+++ R L+K Sbjct: 135 TVIFASYKDDA---LYAIEPSGAFYGYFASCFGKNSNLARAELQK 176 >UniRef50_Q4U9U5 Cluster: Proteasome subunit alpha type; n=3; Piroplasmida|Rep: Proteasome subunit alpha type - Theileria annulata Length = 276 Score = 57.6 bits (133), Expect = 3e-07 Identities = 54/203 (26%), Positives = 86/203 (42%), Gaps = 9/203 (4%) Frame = +3 Query: 84 ITVFSPDGHLLQVEYAQEAVRK-GSTAXXXXXXXXXXXXXEKKSVAK------LQEERTV 242 IT+FSP+G L Q+EYA +AV+ T +KK A+ L + +V Sbjct: 13 ITIFSPEGKLFQLEYALKAVKNCNLTGLAIKDDSAIAVVAQKKLPAQQGNQDVLLDTSSV 72 Query: 243 RKICLLDDHVVMAFAGLTADA-RILINRAQIECQ-SHKLTVEDPVTLEYITRYIAGLKQK 416 + + D + GL D IL Q+ S+K + P ++ + + I+ L Q Sbjct: 73 TSLYHITDEIFALLVGLPGDCLSILYKARQVALDYSYKYGINIPASV--LCQKISDLNQV 130 Query: 417 YTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYT 596 YTQ R + LI + D P +++ + SG + +KA G + LEK Sbjct: 131 YTQHAYMRLHACTGLILSIEPDVGPKIYKFDSSGWFAGYKACGIGAKEQESENALEKTLK 190 Query: 597 ADEVATENGAVKLAIRALLEVVQ 665 E + A+K + EV Q Sbjct: 191 RREAMSLQDAMKSNLHVNTEVHQ 213 >UniRef50_Q9GU37 Cluster: Proteasome subunit alpha type-1; n=8; Trypanosomatidae|Rep: Proteasome subunit alpha type-1 - Trypanosoma brucei brucei Length = 266 Score = 57.6 bits (133), Expect = 3e-07 Identities = 48/174 (27%), Positives = 73/174 (41%), Gaps = 6/174 (3%) Frame = +3 Query: 84 ITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVA-KLQEERTVRKICLL 260 ITVFSP+G L QVEYA +AV + SV KL T+ + + Sbjct: 10 ITVFSPEGSLYQVEYAFKAVTYAGLLTVAIRCKDAVLVFTQHSVPDKLMRPETITSLYNV 69 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 +D+ + G D + L+ +A+ E +K P+ + + + + Q TQ G R Sbjct: 70 NDNTGVCITGRAPDGKALVQKARNEASEYKYRYGMPMLVSVLAKPWQDMAQVRTQQAGMR 129 Query: 441 PFGISCLIGGF---DYDGS--PHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 587 G G D DG+ P ++ +P+G A A G+ FLEK Sbjct: 130 LMGTIMTFVGMEQNDEDGAWIPQIYCVDPAG-GAAVHACAVGKKQIEACAFLEK 182 >UniRef50_Q8ZST5 Cluster: Proteasome, beta subunit; n=5; Thermoproteaceae|Rep: Proteasome, beta subunit - Pyrobaculum aerophilum Length = 203 Score = 56.8 bits (131), Expect = 4e-07 Identities = 49/178 (27%), Positives = 78/178 (43%), Gaps = 1/178 (0%) Frame = +3 Query: 135 EAVRKGSTAXXXXXXXXXXXXXEKK-SVAKLQEERTVRKICLLDDHVVMAFAGLTADARI 311 E V+ G+TA EK+ S +K+ ++DD + +A AG+ AD + Sbjct: 3 EEVQIGATAVGIKAKDGVVLAAEKRVSYGFYTLSSAGKKVFVIDDKLAIASAGIIADMQT 62 Query: 312 LINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFGISCLIGGFDYDGSP 491 L ++ ++++L ++ + T +A L S PF L+GG D +G P Sbjct: 63 LAKILKLNAKAYELEMKRKPS----THSMARLLSVIMFSRRFMPFFAEVLVGGIDEEG-P 117 Query: 492 HLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENGAVKLAIRALLEVVQ 665 HL +P G E A G AK L+ Y D E A KLA++AL ++ Sbjct: 118 HLIVMDPLGSLIEDNYAALGTGAKLAVAVLDTGYRPDITVEE--AKKLAVQALKAAIE 173 >UniRef50_A2BN24 Cluster: Proteasome beta subunit; n=2; Desulfurococcales|Rep: Proteasome beta subunit - Hyperthermus butylicus (strain DSM 5456 / JCM 9403) Length = 204 Score = 56.0 bits (129), Expect = 8e-07 Identities = 38/144 (26%), Positives = 67/144 (46%) Frame = +3 Query: 234 RTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQ 413 +T RK+ + D++ +A AGL AD + + + E + + + +++ + R +A + Sbjct: 37 KTARKVYKITDYLGLALAGLFADLQAISKILRAEIEYYNIVTGRRISVRAVARLLATILY 96 Query: 414 KYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 593 Y PF L+GG + DG+ L+ +P G E A G A LE Y Sbjct: 97 SYKYY----PFLSETLVGGLEADGTAKLYVMDPLGSLIEDDYAAIGSGAPIAIGILENGY 152 Query: 594 TADEVATENGAVKLAIRALLEVVQ 665 + D + + A KLAI A+ ++ Sbjct: 153 SKD--MSVDDAKKLAIAAVRAAIE 174 >UniRef50_Q9P996 Cluster: Proteasome subunit beta precursor; n=10; Euryarchaeota|Rep: Proteasome subunit beta precursor - Archaeoglobus fulgidus Length = 213 Score = 55.6 bits (128), Expect = 1e-06 Identities = 47/180 (26%), Positives = 79/180 (43%), Gaps = 2/180 (1%) Frame = +3 Query: 132 QEAVRKGSTAXXXXXXXXXXXXXEKKS-VAKLQEERTVRKICLLDDHVVMAFAGLTADAR 308 +E + KG+T EK++ + + +KI + D + M AG DA+ Sbjct: 5 EEKIYKGTTTVGLVCKDGVVMATEKRATMGNFIASKAAKKIYQIADRMAMTTAGSVGDAQ 64 Query: 309 ILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFGISCLIGGFDYDGS 488 L +IE +++ E T+ I + L Y P+ + LIGG D +G Sbjct: 65 FLARIIKIEANLYEIRRERKPTVRAIATLTSNLLNSYRYF----PYLVQLLIGGIDSEGK 120 Query: 489 PHLFQTEPSGIYYEWK-ANATGRSAKTVREFLEKNYTADEVATENGAVKLAIRALLEVVQ 665 ++ +P G E K ATG + T LE +T E+ + AV+LA+RA+ ++ Sbjct: 121 -SIYSIDPIGGAIEEKDIVATGSGSLTAYGVLEDRFT-PEIGVDE-AVELAVRAIYSAMK 177 >UniRef50_A0RXV1 Cluster: 20S proteasome, alpha and beta subunit; n=1; Cenarchaeum symbiosum|Rep: 20S proteasome, alpha and beta subunit - Cenarchaeum symbiosum Length = 195 Score = 55.2 bits (127), Expect = 1e-06 Identities = 40/137 (29%), Positives = 66/137 (48%), Gaps = 1/137 (0%) Frame = +3 Query: 246 KICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQ 425 KI +DDH + AG ADA+ +++ + H++ + P+ ++ + R + + + Q Sbjct: 30 KIQRIDDHAGLTLAGGVADAQNIVDVLRYHASLHRIRKQGPIPIKSLARLTSLI---FHQ 86 Query: 426 SNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADE 605 + G PF L+GGFD G P L+ + G E TG + LE+ Y AD Sbjct: 87 NRG-YPFMADILMGGFDAVG-PALYNIDMFGSVEEKSYVTTGSGSPVAYGTLEEEYRADL 144 Query: 606 VATENGAVKL-AIRALL 653 A E V L A++A + Sbjct: 145 TADEAKGVALRAVKAAI 161 >UniRef50_Q58634 Cluster: Proteasome subunit beta precursor; n=9; Euryarchaeota|Rep: Proteasome subunit beta precursor - Methanococcus jannaschii Length = 224 Score = 54.8 bits (126), Expect = 2e-06 Identities = 46/177 (25%), Positives = 75/177 (42%), Gaps = 2/177 (1%) Frame = +3 Query: 141 VRKGSTAXXXXXXXXXXXXXEKK-SVAKLQEERTVRKICLLDDHVVMAFAGLTADARILI 317 V KG+T +K+ S+ L ++ +K+ +DD++ M AG DA+ ++ Sbjct: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 Query: 318 NRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFGISCLIGGFDYDGSPHL 497 E + +K+ + A L S+ PF +IGG+D L Sbjct: 63 RLLIAEAKLYKMRTGRNIP----PLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKL 118 Query: 498 FQTEPSGIYYEWKA-NATGRSAKTVREFLEKNYTADEVATENGAVKLAIRALLEVVQ 665 F +P G E K ATG + LE Y D ++ E G +KLA+ AL ++ Sbjct: 119 FSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRD-MSVEEG-IKLALNALKSAME 173 >UniRef50_Q98S33 Cluster: 26S proteasome SU alpha7; n=1; Guillardia theta|Rep: 26S proteasome SU alpha7 - Guillardia theta (Cryptomonas phi) Length = 241 Score = 54.4 bits (125), Expect = 2e-06 Identities = 47/196 (23%), Positives = 83/196 (42%), Gaps = 2/196 (1%) Frame = +3 Query: 87 TVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDD 266 T+F+P+G LLQ+EY+ + + K + A E S + I L+ Sbjct: 13 TIFTPEGKLLQLEYSSKCINKSNIALGIKCNDGLIIFKEIDSNQYNNDIIECNMIFCLNH 72 Query: 267 HVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPF 446 ++ M +G+T D R L NR E K + +Y+T ++ L + S RP Sbjct: 73 YMAMTSSGITGDFRSLCNRLVDENLIEKYRYGLELNSKYLTHLLSRLFHLNSNSWSLRPL 132 Query: 447 GISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENGA 626 ++G DY S +F G + +TG + + + LE + +E++ Sbjct: 133 ACDIILGFIDY-SSLEIFFISNQGSIIKTNNISTGSACELINFELESIF-KEELSCRKVI 190 Query: 627 VKL--AIRALLEVVQS 668 +K+ + AL +QS Sbjct: 191 LKIIKKLSALTRDLQS 206 >UniRef50_A7DQ84 Cluster: Proteasome endopeptidase complex; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: Proteasome endopeptidase complex - Candidatus Nitrosopumilus maritimus SCM1 Length = 210 Score = 54.4 bits (125), Expect = 2e-06 Identities = 38/135 (28%), Positives = 65/135 (48%) Frame = +3 Query: 246 KICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQ 425 KI +DDH + AG ADA+ +++ + H++ P+++ + R + + + Q Sbjct: 45 KIQKIDDHAGLTLAGGVADAQNIVDILRYHSNLHRVEKHGPISIHSLARLCSLI---FHQ 101 Query: 426 SNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADE 605 + G PF L+GG+D +G P LF + G + TG + LE+ Y D Sbjct: 102 NRG-YPFMADILVGGYDAEG-PALFNIDMFGSVEKKAYVTTGSGSPVAYGLLEEEYREDL 159 Query: 606 VATENGAVKLAIRAL 650 E A K+A+RA+ Sbjct: 160 TVEE--AKKIALRAV 172 >UniRef50_A2F568 Cluster: Family T1, proteasome alpha subunit, threonine peptidase; n=1; Trichomonas vaginalis G3|Rep: Family T1, proteasome alpha subunit, threonine peptidase - Trichomonas vaginalis G3 Length = 241 Score = 53.2 bits (122), Expect = 5e-06 Identities = 44/170 (25%), Positives = 75/170 (44%), Gaps = 2/170 (1%) Frame = +3 Query: 84 ITVFSPDGHLLQVEYAQEAVRKGS-TAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 260 +TVFS +G L QVEY+ +AV++ TA +KK KL + TV + + Sbjct: 9 LTVFSAEGRLWQVEYSFKAVKQAEVTAVAVKSKNAVCVAVQKKVSDKLIDPSTVTHMYRI 68 Query: 261 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 440 D+V GL +D ++ + + + + + + + ++ Q +Q R Sbjct: 69 TDNVGACLVGLPSDVNFIVMLLRSFANNFEYKQGFSIPVSILAQMLSERHQLESQLVYVR 128 Query: 441 PFGISCLIGGFD-YDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 587 P +S ++ G D S L++ EPSG ++A A G LEK Sbjct: 129 PSAVSAILFGLDGPSDSFALYKIEPSGYSNGFRAVACGVKEIEAMSALEK 178 >UniRef50_P28061 Cluster: Proteasome subunit beta precursor; n=4; Thermoplasmatales|Rep: Proteasome subunit beta precursor - Thermoplasma acidophilum Length = 211 Score = 50.0 bits (114), Expect = 5e-05 Identities = 35/136 (25%), Positives = 65/136 (47%) Frame = +3 Query: 243 RKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYT 422 +K+ +D + M AGL DA++L+ + E + ++L + +E + ++ + + Sbjct: 40 KKLFQIDTYTGMTIAGLVGDAQVLVRYMKAELELYRLQRRVNMPIEAVATLLSNMLNQVK 99 Query: 423 QSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTAD 602 P+ + L+GG D +PH+F + +G E +TG + V LE Y+ Sbjct: 100 YM----PYMVQLLVGGIDT--APHVFSIDAAGGSVEDIYASTGSGSPFVYGVLESQYS-- 151 Query: 603 EVATENGAVKLAIRAL 650 E T + V L IRA+ Sbjct: 152 EKMTVDEGVDLVIRAI 167 >UniRef50_Q5KFP2 Cluster: Proteasome subunit beta type; n=3; Fungi/Metazoa group|Rep: Proteasome subunit beta type - Cryptococcus neoformans (Filobasidiella neoformans) Length = 272 Score = 48.0 bits (109), Expect = 2e-04 Identities = 35/135 (25%), Positives = 58/135 (42%), Gaps = 2/135 (1%) Frame = +3 Query: 228 EERTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGL 407 + R RK+ L D VV+A G AD + R + + ++ + L+ I R I Sbjct: 58 QTRYARKVWQLTDKVVLATNGFAADGNNFVKRVKQRLEWYEHAHNKAMGLKSIARMIQ-- 115 Query: 408 KQKYTQSNGRR--PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFL 581 T G+R P+ + ++GG + DGS ++ +P G Y A G + ++ FL Sbjct: 116 ----TMLYGKRFFPYYVYNILGGIEEDGSGAVYSFDPVGSYEREACRAAGAAQSLIQPFL 171 Query: 582 EKNYTADEVATENGA 626 + E GA Sbjct: 172 DNQVYFKNQQPEPGA 186 >UniRef50_A7SI53 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 1628 Score = 47.2 bits (107), Expect = 4e-04 Identities = 26/70 (37%), Positives = 40/70 (57%) Frame = +3 Query: 105 GHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDDHVVMAF 284 G + Q+EYA EAV++GS K++ ++L + +KI +D HV ++ Sbjct: 705 GRIHQIEYAMEAVKQGSATVALKSKTHAVIVALKRAPSELSAHQ--KKILPIDTHVGVSI 762 Query: 285 AGLTADARIL 314 AGLTADAR+L Sbjct: 763 AGLTADARLL 772 >UniRef50_Q8SQP9 Cluster: PROTEASOME REGULATORY SUBUNIT 8; n=1; Encephalitozoon cuniculi|Rep: PROTEASOME REGULATORY SUBUNIT 8 - Encephalitozoon cuniculi Length = 242 Score = 47.2 bits (107), Expect = 4e-04 Identities = 38/167 (22%), Positives = 69/167 (41%) Frame = +3 Query: 87 TVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDD 266 T+++ G + Q+ YAQ+A G T EK V+ L + KI + + Sbjct: 8 TIYTTTGQIDQLSYAQKAADSGDTCIGMKSKHGVVLLAEKPRVSPLYILESDEKIRKIGN 67 Query: 267 HVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPF 446 + + G+++D + + HK + T + Y+ + +T+ R Sbjct: 68 TIGVVCTGMSSDTFYVGCAIKDYVFHHKENFNEDPTPGMMKVYLNDIFHYFTRGINLRVL 127 Query: 447 GISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 587 G + L + DGS L T+ SG +KA G+ + ++ LEK Sbjct: 128 GANTLTSVYK-DGSFSLLHTDCSGKTLSYKAACIGKGTRRIKTELEK 173 >UniRef50_P22141 Cluster: Proteasome component C11; n=36; Ascomycota|Rep: Proteasome component C11 - Saccharomyces cerevisiae (Baker's yeast) Length = 198 Score = 47.2 bits (107), Expect = 4e-04 Identities = 36/135 (26%), Positives = 63/135 (46%), Gaps = 4/135 (2%) Frame = +3 Query: 258 LDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQS-NG 434 L H +M+FAG D Q Q + + + ++ + ++ ++ +Q+ +S Sbjct: 38 LSPHTLMSFAGEAGDTVQFAEYIQANIQLYSIREDYELSPQAVSSFV---RQELAKSIRS 94 Query: 435 RRPFGISCLIGGFD-YDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVA 611 RRP+ ++ LIGG+D P L+Q + G E A G S L+ +Y D + Sbjct: 95 RRPYQVNVLIGGYDKKKNKPELYQIDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPD-MT 153 Query: 612 TENG--AVKLAIRAL 650 TE G +KL ++ L Sbjct: 154 TEEGLDLLKLCVQEL 168 >UniRef50_O23370 Cluster: Cell wall protein like; n=15; Magnoliophyta|Rep: Cell wall protein like - Arabidopsis thaliana (Mouse-ear cress) Length = 428 Score = 46.4 bits (105), Expect = 6e-04 Identities = 22/67 (32%), Positives = 39/67 (58%) Frame = +3 Query: 450 ISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENGAV 629 ++C + G+D + L+ ++PSG Y W+A A G + + + L+++Y D AT V Sbjct: 354 VACAVAGWDRNHGFQLYMSDPSGNYGGWQAAAVGANNQAAQSILKQDYKDD--ATREEVV 411 Query: 630 KLAIRAL 650 +LAI+ L Sbjct: 412 QLAIKVL 418 >UniRef50_Q8ZYF2 Cluster: Proteasome beta subunit; n=5; Thermoproteaceae|Rep: Proteasome beta subunit - Pyrobaculum aerophilum Length = 202 Score = 46.0 bits (104), Expect = 8e-04 Identities = 35/141 (24%), Positives = 66/141 (46%) Frame = +3 Query: 246 KICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQ 425 KI +DDHV +G AD + +++ + +K+ + P+ + + Y++ L Y++ Sbjct: 34 KIWKIDDHVAATMSGGVADLQSVLSFLTLRAHEYKIEYKRPIPISALVNYMS-LILFYSR 92 Query: 426 SNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADE 605 + + +IGG D + L+ + G + K ATG + + LE Y D Sbjct: 93 P---YIYIVHSIIGGVDEEEGAVLYMVDWLGTVTKEKYIATGSGSPYAKGALEVGYRED- 148 Query: 606 VATENGAVKLAIRALLEVVQS 668 T AV LAI+A+ +++ Sbjct: 149 -MTLEDAVDLAIKAVKAAIRN 168 >UniRef50_A2BN27 Cluster: Proteasome beta; n=3; Desulfurococcales|Rep: Proteasome beta - Hyperthermus butylicus (strain DSM 5456 / JCM 9403) Length = 212 Score = 45.6 bits (103), Expect = 0.001 Identities = 37/144 (25%), Positives = 68/144 (47%) Frame = +3 Query: 234 RTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQ 413 + +KI + D++ M AGL ADA++L +++ + +++ +Y++ + Sbjct: 44 KRTKKIIKITDYMAMTTAGLVADAQMLAEWLANHTHYYEIVNKRRMSIHAAAQYLSII-- 101 Query: 414 KYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 593 S P+ + L+GG YD P L+ + G E K ATG + T +E Y Sbjct: 102 --LHSAKFYPYIVQLLLGG--YDTQPRLYNIDWFGSVTEEKYVATGSGSPTAIGVIEDQY 157 Query: 594 TADEVATENGAVKLAIRALLEVVQ 665 + + E AV+LA RA+ ++ Sbjct: 158 SPNLSMEE--AVELAKRAVASSIR 179 >UniRef50_Q8IAR3 Cluster: Proteasome subunit alpha, putative; n=5; Plasmodium|Rep: Proteasome subunit alpha, putative - Plasmodium falciparum (isolate 3D7) Length = 284 Score = 44.4 bits (100), Expect = 0.003 Identities = 31/121 (25%), Positives = 52/121 (42%), Gaps = 7/121 (5%) Frame = +3 Query: 84 ITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVA-------KLQEERTV 242 +T+FSPDG+L Q+EYA +AV+ + +K +A KL + + Sbjct: 13 LTIFSPDGNLYQIEYAIKAVKNTNITSVGVKGENCAVIISQKKMATQYISQDKLLDYNNI 72 Query: 243 RKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYT 422 I + D + + G+ D ++ +A+ E + V E + R I Q YT Sbjct: 73 TNIYNITDEIGCSMVGMPGDCLSMVYKARSEASEFLYSNGYNVNAETLCRNICDKIQVYT 132 Query: 423 Q 425 Q Sbjct: 133 Q 133 >UniRef50_UPI0000499449 Cluster: proteasome beta subunit; n=1; Entamoeba histolytica HM-1:IMSS|Rep: proteasome beta subunit - Entamoeba histolytica HM-1:IMSS Length = 252 Score = 43.6 bits (98), Expect = 0.004 Identities = 30/138 (21%), Positives = 60/138 (43%) Frame = +3 Query: 237 TVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQK 416 +V+K + H++ AG AD +C+ +L + P+++ ++ +A + + Sbjct: 68 SVQKYIPITSHIIGTMAGGAADCAYWERELTRQCRLFELRNKPPISVAAASKMLANILYQ 127 Query: 417 YTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYT 596 Y N + +I G+D G PH+F E G+ + G + ++ Y Sbjct: 128 YRNYN----LSVGSMICGYDKTG-PHIFYVEDGGVRIPGHLFSVGSGSPYAVSLIDSEY- 181 Query: 597 ADEVATENGAVKLAIRAL 650 D + A++LA RA+ Sbjct: 182 -DYNMPKEKAIELARRAI 198 >UniRef50_Q98RN2 Cluster: 26s proteasome SU A6; n=1; Guillardia theta|Rep: 26s proteasome SU A6 - Guillardia theta (Cryptomonas phi) Length = 235 Score = 43.6 bits (98), Expect = 0.004 Identities = 35/157 (22%), Positives = 66/157 (42%) Frame = +3 Query: 87 TVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDD 266 T+F DG +LQ+E+A + +G E K + + +D+ Sbjct: 6 TLFDSDGKILQLEFALKIPNQGKMIFSFKSINHSYIISEIHE--KKTNNKFFNRFYSIDN 63 Query: 267 HVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPF 446 ++ + +G+ DA+ + N K ++ ++EYI++ I+ T +RP+ Sbjct: 64 NIGLGISGIFFDAKKIFNFCVELNIKIKQAFKNFCSVEYISKKISEAFSNNTLKINQRPY 123 Query: 447 GISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRS 557 I+ I GF D P +F+ G+ K +G S Sbjct: 124 AINVFIIGFS-DKGPIIFEISTDGLMTYKKTCLSGSS 159 >UniRef50_A1RX71 Cluster: Proteasome endopeptidase complex; n=1; Thermofilum pendens Hrk 5|Rep: Proteasome endopeptidase complex - Thermofilum pendens (strain Hrk 5) Length = 204 Score = 43.2 bits (97), Expect = 0.006 Identities = 36/136 (26%), Positives = 63/136 (46%) Frame = +3 Query: 243 RKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYT 422 +K+ + D + MA AGL AD + L + E + ++L + ++ + T +A L Sbjct: 37 KKVYRILDKMGMASAGLMADMQTLARIVEAEMRLYEL--DSNISPKVWT--VAKLLSYIL 92 Query: 423 QSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTAD 602 P+ ++GG D +GS HL+ +P G E A G + +E NY D Sbjct: 93 YERRLFPYYAEIVVGGLDEEGS-HLYSLDPIGAIIEDDYVALGSGTQLAISIVESNYKKD 151 Query: 603 EVATENGAVKLAIRAL 650 E A+ LA++++ Sbjct: 152 MSLDE--ALSLALKSV 165 >UniRef50_Q9UXF3 Cluster: Proteasome subunit beta precursor; n=5; Sulfolobaceae|Rep: Proteasome subunit beta precursor - Sulfolobus solfataricus Length = 208 Score = 43.2 bits (97), Expect = 0.006 Identities = 44/188 (23%), Positives = 77/188 (40%), Gaps = 1/188 (0%) Frame = +3 Query: 105 GHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKL-QEERTVRKICLLDDHVVMA 281 G+ LQ+E + KG+T ++++ A + VRK+ + D + + Sbjct: 2 GNELQLE---NKILKGTTTVGIRVNDGVILAADRRASAGFFVANKMVRKVLYITDKIGIT 58 Query: 282 FAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFGISCL 461 AG AD + + + + + +T P++++ I +A + + P+ + L Sbjct: 59 TAGSVADLQFIYDVLKNIYHYNSITKYGPISIKGIATRLANV----LSATKYFPYIVQIL 114 Query: 462 IGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENGAVKLAI 641 IGG YD P LF + G E ATG + LE Y E A LA Sbjct: 115 IGG--YDDQPRLFNLDYLGDITEENYVATGSGSPVAMGVLEDEYNPKMTLDE--AADLAK 170 Query: 642 RALLEVVQ 665 RA+ ++ Sbjct: 171 RAVFSAIK 178 >UniRef50_A6R393 Cluster: Proteasome component C5; n=5; Ascomycota|Rep: Proteasome component C5 - Ajellomyces capsulatus NAm1 Length = 266 Score = 42.7 bits (96), Expect = 0.008 Identities = 26/106 (24%), Positives = 46/106 (43%) Frame = +3 Query: 267 HVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPF 446 H+V++ G AD R L R + +K P+++ + +A + S P+ Sbjct: 89 HLVLSVVGFAADGRALKERLDAIVKMYKYKHGKPMSVNACAQRLATI----LYSKRFFPY 144 Query: 447 GISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLE 584 + ++ G D DG L+ +P G Y A G +A + FL+ Sbjct: 145 YVHAILAGMDEDGKGALYSYDPVGSYEREYCRAAGAAASLIMPFLD 190 >UniRef50_Q23FB2 Cluster: Proteasome, putative; n=5; Oligohymenophorea|Rep: Proteasome, putative - Tetrahymena thermophila SB210 Length = 297 Score = 41.5 bits (93), Expect = 0.018 Identities = 23/95 (24%), Positives = 48/95 (50%) Frame = +3 Query: 204 KKSVAKLQEERTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEY 383 + S TVRKI ++D ++ AG AD + IEC+ ++L + V++ Sbjct: 93 RASQGSFDASETVRKIIEINDQLLGTMAGGAADCQFWEQYLAIECRKYQLQNREKVSVAA 152 Query: 384 ITRYIAGLKQKYTQSNGRRPFGISCLIGGFDYDGS 488 +R + + Y +++G + C++ G+D++G+ Sbjct: 153 ASRILINILYSY-RNHG---LSMGCMLTGWDHEGA 183 >UniRef50_Q8T8V8 Cluster: Proteasome subunit beta type; n=13; Neoptera|Rep: Proteasome subunit beta type - Drosophila melanogaster (Fruit fly) Length = 315 Score = 41.1 bits (92), Expect = 0.024 Identities = 34/139 (24%), Positives = 60/139 (43%) Frame = +3 Query: 234 RTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQ 413 +T+RKI L+D+++ AG AD EC+ H+L +T++ R I + Sbjct: 100 QTMRKIVELNDYMLGTLAGGAADCVYWDRVLAKECRLHQLRYRKRMTVDTAARIICNIST 159 Query: 414 KYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 593 +Y + ++ GFD +G P L + G+ + + G + L+ Y Sbjct: 160 EYKGMG----LVMGMMLAGFDDEG-PKLIYVDSEGMRSHGQVFSVGSGSPYALGVLDTGY 214 Query: 594 TADEVATENGAVKLAIRAL 650 D ++ A LA RA+ Sbjct: 215 RYD--LSDQEAYDLARRAI 231 >UniRef50_A2DD57 Cluster: Proteasome subunit beta type; n=1; Trichomonas vaginalis G3|Rep: Proteasome subunit beta type - Trichomonas vaginalis G3 Length = 256 Score = 41.1 bits (92), Expect = 0.024 Identities = 35/139 (25%), Positives = 58/139 (41%) Frame = +3 Query: 234 RTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQ 413 +TV KI L +++ AG AD + + Q HK + P+T+ ++ + Sbjct: 82 QTVMKILPLAPNMIGTMAGGAADCQYWLRNLSRLIQLHKFRYQQPLTVAAASKILVNELY 141 Query: 414 KYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 593 +Y N I +I G+D G PH+F + G K + G + L+ Y Sbjct: 142 RYKGYN----LSIGSMICGYDNTG-PHIFYIDNHGSRIAGKRFSVGSGSTHAYGVLDTCY 196 Query: 594 TADEVATENGAVKLAIRAL 650 D T+ A +L RA+ Sbjct: 197 RED--MTKEEACELGRRAI 213 >UniRef50_Q966I8 Cluster: Proteasome subunit beta type; n=2; Caenorhabditis|Rep: Proteasome subunit beta type - Caenorhabditis elegans Length = 239 Score = 40.7 bits (91), Expect = 0.031 Identities = 33/169 (19%), Positives = 65/169 (38%), Gaps = 1/169 (0%) Frame = +3 Query: 126 YAQEAVRKGSTAXXXXXXXXXXXXXEKK-SVAKLQEERTVRKICLLDDHVVMAFAGLTAD 302 Y QE + G+T + + S R KI + D++V+ +G AD Sbjct: 15 YPQEEISTGTTLIAMEYNGGVVVGTDSRTSAGSFITSRATNKITPITDNMVVCRSGSAAD 74 Query: 303 ARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFGISCLIGGFDYD 482 + + + A+ + +T PVT+ ++ Y R S L+ G+D + Sbjct: 75 TQAIADIAKYHIDVYTMTENKPVTIYRSSQIFRQFLYNY-----REQLSASVLVAGWDEE 129 Query: 483 GSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENGAV 629 ++ G ++ A+G + V+ FL+ + + E A+ Sbjct: 130 LGGQVYAIPIGGFVSRQRSTASGSGSTFVQGFLDSQWRPNLTLEECKAI 178 >UniRef50_P23724 Cluster: Proteasome component C5; n=23; Fungi/Metazoa group|Rep: Proteasome component C5 - Saccharomyces cerevisiae (Baker's yeast) Length = 241 Score = 40.3 bits (90), Expect = 0.041 Identities = 34/134 (25%), Positives = 58/134 (43%), Gaps = 5/134 (3%) Frame = +3 Query: 264 DHVVMAFAGLTADARILINRAQIECQSHKLTVEDP-VTLEYITRYIAGLKQKYTQSNGRR 440 D++VM+ G AD L+ R + + + D +++ R I L G+R Sbjct: 67 DNIVMSANGFAADGDALVKRFKNSVKWYHFDHNDKKLSINSAARNIQHLLY------GKR 120 Query: 441 --PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK--NYTADEV 608 P+ + +I G D DG ++ +P G Y + A G +A + FL+ N+ Sbjct: 121 FFPYYVHTIIAGLDEDGKGAVYSFDPVGSYEREQCRAGGAAASLIMPFLDNQVNFKNQYE 180 Query: 609 ATENGAVKLAIRAL 650 NG VK ++ L Sbjct: 181 PGTNGKVKKPLKYL 194 >UniRef50_Q6CA23 Cluster: Yarrowia lipolytica chromosome D of strain CLIB122 of Yarrowia lipolytica; n=1; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome D of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 238 Score = 39.1 bits (87), Expect = 0.096 Identities = 31/140 (22%), Positives = 57/140 (40%) Frame = +3 Query: 246 KICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQ 425 K+ + D++++ G +AD LI + + + P+ ++ R I Q Sbjct: 67 KVFDVGDNILVTANGFSADGDALIENIKQHVELYHYQNNKPLKVQSCARAI----QHMLY 122 Query: 426 SNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADE 605 + P+ + +I G D +G ++ +P G Y A G +A V FL+ Sbjct: 123 NKRFFPYYVHTIIAGLDEEGKGAVYSYDPVGSYEREFCRAGGSAASLVMPFLDSQVNKKN 182 Query: 606 VATENGAVKLAIRALLEVVQ 665 EN L + L+VV+ Sbjct: 183 QQVEN-PPPLTLEEALKVVK 201 >UniRef50_A2F8W4 Cluster: Family T1, proteasome beta subunit, threonine peptidase; n=2; Trichomonas vaginalis G3|Rep: Family T1, proteasome beta subunit, threonine peptidase - Trichomonas vaginalis G3 Length = 191 Score = 36.7 bits (81), Expect = 0.51 Identities = 33/137 (24%), Positives = 58/137 (42%), Gaps = 2/137 (1%) Frame = +3 Query: 246 KICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQ 425 +I LDD +A +G T D L Q +K ++ + + +I K + Sbjct: 34 RIAQLDDRHALAMSGETGDCLQLSEYLQGNVALYKFRNGVELSSDALAHFIRHTMAKAVR 93 Query: 426 SNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADE 605 + P+ ++ L+ G YDG PHL+ + G A G V +K+Y + Sbjct: 94 KS---PYEVNMLLSG--YDGKPHLYFMDYLGTLQSIPYGAQGYCQYFVMSVFDKHY-KEG 147 Query: 606 VATENG--AVKLAIRAL 650 + E+G +KLA+ + Sbjct: 148 LTLEDGKELMKLALNQI 164 >UniRef50_P40306 Cluster: Proteasome subunit beta type-10 precursor; n=28; Eukaryota|Rep: Proteasome subunit beta type-10 precursor - Homo sapiens (Human) Length = 273 Score = 36.7 bits (81), Expect = 0.51 Identities = 29/121 (23%), Positives = 47/121 (38%) Frame = +3 Query: 231 ERTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLK 410 +++ KI + + AG+ ADA + + + H L+ + +TR L+ Sbjct: 67 DKSCEKIHFIAPKIYCCGAGVAADAEMTTRMVASKMELHALSTGREPRVATVTRI---LR 123 Query: 411 QKYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKN 590 Q + G G S ++GG D G P L+ P G Y A G LE Sbjct: 124 QTLFRYQGH--VGASLIVGGVDLTG-PQLYGVHPHGSYSRLPFTALGSGQDAALAVLEDR 180 Query: 591 Y 593 + Sbjct: 181 F 181 >UniRef50_UPI000023D2A5 Cluster: hypothetical protein FG06803.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG06803.1 - Gibberella zeae PH-1 Length = 235 Score = 36.3 bits (80), Expect = 0.67 Identities = 20/82 (24%), Positives = 38/82 (46%), Gaps = 1/82 (1%) Frame = +3 Query: 258 LDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGR 437 L+ H ++AF+G D Q Q + + E ++ + ++ G + T R Sbjct: 43 LNKHTLLAFSGEAGDTVQFAEYIQRNAQLYSMRNESDLSPSALAHFVRG--ELATSLRSR 100 Query: 438 RPFGISCLIGGFD-YDGSPHLF 500 +P+ ++ L+GG D G P L+ Sbjct: 101 KPYNVNLLMGGVDPITGKPSLY 122 >UniRef50_Q1YM98 Cluster: Putative uncharacterized protein; n=1; Aurantimonas sp. SI85-9A1|Rep: Putative uncharacterized protein - Aurantimonas sp. SI85-9A1 Length = 352 Score = 35.9 bits (79), Expect = 0.89 Identities = 20/73 (27%), Positives = 40/73 (54%) Frame = +3 Query: 210 SVAKLQEERTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYIT 389 ++ ++ E T R + D H VMAFAGL +A +L R ++ C L + P +++ Sbjct: 64 ALTRIAGEETRRWLEAFDPHKVMAFAGLVLEACVLDERWRVACWRLDLDEKTP----HLS 119 Query: 390 RYIAGLKQKYTQS 428 ++ L+Q ++++ Sbjct: 120 VFVVPLRQSHSKT 132 >UniRef50_O24079 Cluster: Proteasome subunit; n=1; Medicago sativa|Rep: Proteasome subunit - Medicago sativa (Alfalfa) Length = 101 Score = 35.1 bits (77), Expect = 1.6 Identities = 18/48 (37%), Positives = 27/48 (56%) Frame = +3 Query: 507 EPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENGAVKLAIRAL 650 +PSG Y WKA A G + + + L+++Y D T AV LA++ L Sbjct: 2 DPSGNYGGWKAGAIGANNQAAQSILKQDYKDD--ITREEAVNLALKVL 47 >UniRef50_Q0UWV2 Cluster: Predicted protein; n=4; Pezizomycotina|Rep: Predicted protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 260 Score = 35.1 bits (77), Expect = 1.6 Identities = 34/153 (22%), Positives = 65/153 (42%), Gaps = 1/153 (0%) Frame = +3 Query: 210 SVAKLQEERTVRKICLLDDHVVMAFAGLTADARILINRAQ-IECQSHKLTVEDPVTLEYI 386 S+A+ + + +RK +D VV+ F G +D + L ++ + + E + + + Sbjct: 64 SLARFTDVKRLRKF---NDEVVVGFGGDVSDMQYLDRLLNSLDIRETYSSNETALNAKNL 120 Query: 387 TRYIAGLKQKYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKT 566 Y+A K Y + + P LI G D + P L + G + + ATG A Sbjct: 121 HTYLA--KVMYNRRSKFDPLWNHLLIAGMDGESKPFLASADLLGTTFSSPSLATGFGAHL 178 Query: 567 VREFLEKNYTADEVATENGAVKLAIRALLEVVQ 665 + L + DE + E + A+ + E ++ Sbjct: 179 AQPIL-RTILPDEASVEKVTKEQAVEKIKECMK 210 >UniRef50_Q9VNA5 Cluster: Probable proteasome subunit beta type-4; n=3; Sophophora|Rep: Probable proteasome subunit beta type-4 - Drosophila melanogaster (Fruit fly) Length = 268 Score = 35.1 bits (77), Expect = 1.6 Identities = 33/156 (21%), Positives = 69/156 (44%), Gaps = 5/156 (3%) Frame = +3 Query: 210 SVAKLQEERTVRKICLLDDHVVMAFAGLTADARIL---INRAQIE--CQSHKLTVEDPVT 374 S + + + ++ ++ ++++ +G AD + + I++ IE C + ++ Sbjct: 78 SYGSMARYQNIERVFKVNKNILLGGSGDFADIQSIKRNIDQKMIEDQCCDDNIEMKPKSL 137 Query: 375 LEYITRYIAGLKQKYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGR 554 ++TR + Y + + P I ++GG D +G+P+L + G YE ATG Sbjct: 138 ASWMTRVL------YNRRSRMNPLYIDVVVGGVDNEGTPYLANVDLRGRSYEDYVVATGF 191 Query: 555 SAKTVREFLEKNYTADEVATENGAVKLAIRALLEVV 662 + + + D T A +L IR +EV+ Sbjct: 192 ARHLAVPLVREKKPKDRDFTAVEASEL-IRTCMEVL 226 >UniRef50_A2DSN0 Cluster: Cellulosomal scaffoldin anchoring protein, putative; n=1; Trichomonas vaginalis G3|Rep: Cellulosomal scaffoldin anchoring protein, putative - Trichomonas vaginalis G3 Length = 637 Score = 33.9 bits (74), Expect = 3.6 Identities = 13/37 (35%), Positives = 24/37 (64%) Frame = -2 Query: 528 HNIYQKVQFGTSVVNHHSRILLSNTKYQMVDDHCSEY 418 H ++Q V F S +NH+ + ++++ KY + +HCS Y Sbjct: 36 HYLFQYVTF--SNINHYGKYIINSAKYMLKMEHCSMY 70 >UniRef50_O23717 Cluster: Proteasome subunit beta type-5-A precursor; n=13; Viridiplantae|Rep: Proteasome subunit beta type-5-A precursor - Arabidopsis thaliana (Mouse-ear cress) Length = 274 Score = 33.9 bits (74), Expect = 3.6 Identities = 29/139 (20%), Positives = 61/139 (43%) Frame = +3 Query: 234 RTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQ 413 ++V+KI ++ +++ AG AD + I+C+ H+L + +++ ++ +A + Sbjct: 86 QSVKKIIEINPYMLGTMAGGAADCQFWHRNLGIKCRLHELANKRRISVSGASKLLANMLY 145 Query: 414 KYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 593 Y + +I G+D G P L+ + G + + G + L+ Y Sbjct: 146 SYRGMG----LSVGTMIAGWDETG-PGLYYVDNEGGRLKGDRFSVGSGSPYAYGVLDSGY 200 Query: 594 TADEVATENGAVKLAIRAL 650 D E A +LA R++ Sbjct: 201 KYDMSVEE--ASELARRSI 217 >UniRef50_Q00826 Cluster: Probable proteasome subunit beta type-2; n=2; Filobasidiella neoformans|Rep: Probable proteasome subunit beta type-2 - Cryptococcus neoformans (Filobasidiella neoformans) Length = 224 Score = 33.9 bits (74), Expect = 3.6 Identities = 22/99 (22%), Positives = 46/99 (46%), Gaps = 1/99 (1%) Frame = +3 Query: 207 KSVAKLQEERTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYI 386 +S+ +++ + K+ L H+ MAF+G D + + + + P+ Sbjct: 23 RSIVRMKSDEN--KLKTLGPHLAMAFSGEPGDTNNFAEYIERNMRLYNIRNHFPLLPPAA 80 Query: 387 TRYIAGLKQKYTQSNGRRPFGISCLIGGFDYDGS-PHLF 500 + ++ + +S R P+ ++ L+GGFD S PHL+ Sbjct: 81 SAWVRRTLAEAIRS--RHPYAVNLLLGGFDTTTSKPHLY 117 >UniRef50_Q0HJB8 Cluster: Exodeoxyribonuclease V, gamma subunit; n=5; Shewanella|Rep: Exodeoxyribonuclease V, gamma subunit - Shewanella sp. (strain MR-4) Length = 1236 Score = 33.5 bits (73), Expect = 4.8 Identities = 21/74 (28%), Positives = 33/74 (44%) Frame = +3 Query: 444 FGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATENG 623 FGI LI G+ L+Q+ P G++Y A G+SA+ + + L DE Sbjct: 548 FGIKRLILGYALRDDAPLYQSSPPGMHYLTVAGVEGQSAQALGKLLNFIEVLDETTQVLA 607 Query: 624 AVKLAIRALLEVVQ 665 + LLE+ + Sbjct: 608 KAQAPSLRLLELTE 621 >UniRef50_A4RRA7 Cluster: Proteasome subunit beta type; n=2; Ostreococcus|Rep: Proteasome subunit beta type - Ostreococcus lucimarinus CCE9901 Length = 246 Score = 33.5 bits (73), Expect = 4.8 Identities = 20/120 (16%), Positives = 47/120 (39%) Frame = +3 Query: 234 RTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQ 413 R K+C L+D +M +G AD L + H++ +++ ++ + + Sbjct: 46 RASDKMCALNDRTIMCRSGSAADTEALAGYVRNIVSQHEMELDEIADVKTVATIANQIGY 105 Query: 414 KYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 593 + +N R ++GG+D ++ G + + G + + FL+ + Sbjct: 106 QNKGANRGRGLSAYTIVGGWDKRRGSQVYACTAGGNMIKERWTTDGSGSTYIWGFLDSGW 165 >UniRef50_Q2J9Q3 Cluster: 20S proteasome, A and B subunits; n=23; Actinomycetales|Rep: 20S proteasome, A and B subunits - Frankia sp. (strain CcI3) Length = 304 Score = 33.1 bits (72), Expect = 6.3 Identities = 29/144 (20%), Positives = 64/144 (44%), Gaps = 2/144 (1%) Frame = +3 Query: 231 ERTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLK 410 +R V K+ DD+ + +AG LI Q+E + ++ ++L+ +A + Sbjct: 110 QRDVEKVHHADDYSCVGYAGTAGVGAELIRLFQVELEHYEKIEGSTLSLDAKANRLAAM- 168 Query: 411 QKYTQSNGRRPFGISCLIGGFDYD-GSPHLFQTEPSGIYYEWKA-NATGRSAKTVREFLE 584 K + + L G+D D G +F + + E + + G + + L+ Sbjct: 169 VKGNLPMALQGLAVVPLFAGYDLDTGKGRIFSYDIAAAKSEERTYESIGSGSVFAKGSLK 228 Query: 585 KNYTADEVATENGAVKLAIRALLE 656 K + +D +++ AV++++ AL + Sbjct: 229 KRFRSD--LSQDDAVRISVEALYD 250 >UniRef50_Q7QXH2 Cluster: GLP_14_13300_13022; n=1; Giardia lamblia ATCC 50803|Rep: GLP_14_13300_13022 - Giardia lamblia ATCC 50803 Length = 92 Score = 33.1 bits (72), Expect = 6.3 Identities = 25/60 (41%), Positives = 26/60 (43%) Frame = -1 Query: 265 SSKRHIFLTVRSSCNLATDFFSXXXXXXXXXXXXTAVDPFLTAS*AYSTCNKCPSGENTV 86 SS IF R SCNLA S TA P TA A ST +CPSG TV Sbjct: 4 SSTSKIFWEARGSCNLAVCLRSMASTMPAAERTATADVPRSTALCACSTWIRCPSGLKTV 63 >UniRef50_Q5CU00 Cluster: Pre3p/proteasome regulatory subunit beta type 6, NTN hydrolase fold; n=3; Cryptosporidium|Rep: Pre3p/proteasome regulatory subunit beta type 6, NTN hydrolase fold - Cryptosporidium parvum Iowa II Length = 248 Score = 33.1 bits (72), Expect = 6.3 Identities = 30/168 (17%), Positives = 65/168 (38%), Gaps = 1/168 (0%) Frame = +3 Query: 102 DGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXE-KKSVAKLQEERTVRKICLLDDHVVM 278 D ++++++ + G+T + + S + R RKI + D V M Sbjct: 35 DQKIMELDFLNGEIETGTTIVALKYKDGLVLAADGRTSTGPIIAFRAARKITQITDKVFM 94 Query: 279 AFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFGISC 458 +G AD +I+ + Q H+L + + + +A + + + N + Sbjct: 95 CRSGSAADTQIISRYVRRIVQDHELETGEDTKV----KSVASVARLISYQN-KEHLLADM 149 Query: 459 LIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTAD 602 +I G D +G +F+ G E +G + + L+ Y ++ Sbjct: 150 IIAGMDPNGEFKVFRIPLGGTLIEGSYAISGSGSGYIYSMLDSKYHSE 197 >UniRef50_A0CW62 Cluster: Proteasome subunit beta type; n=3; Oligohymenophorea|Rep: Proteasome subunit beta type - Paramecium tetraurelia Length = 194 Score = 33.1 bits (72), Expect = 6.3 Identities = 33/130 (25%), Positives = 54/130 (41%), Gaps = 2/130 (1%) Frame = +3 Query: 210 SVAKLQEERTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYIT 389 S+ K++E T KI LDDH + +G AD +I ++H L + Sbjct: 24 SILKIKE--TEDKILKLDDHKIFGISGEGADRNSF---GEIVHKNHCLIRYKTGGYMNLQ 78 Query: 390 RYIAGLKQKYTQSNGRR--PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAK 563 ++ Y Q+ R P + L+GG D DG+P L+ + G + A G + Sbjct: 79 ETAHFVRSMYAQAIRSRDGPHQCNGLLGGVDSDGTPSLYWLDYLGSLQKITRGAQGYANY 138 Query: 564 TVREFLEKNY 593 + L+ Y Sbjct: 139 FLLGLLDNQY 148 >UniRef50_A0P0V6 Cluster: Putative uncharacterized protein; n=2; Stappia aggregata IAM 12614|Rep: Putative uncharacterized protein - Stappia aggregata IAM 12614 Length = 82 Score = 32.7 bits (71), Expect = 8.3 Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 6/58 (10%) Frame = +3 Query: 453 SCLI-GGF--DYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKN---YTADEV 608 +CL+ GF D DG+P LF+ +P G W + R+ + +R F++KN +T D++ Sbjct: 22 ACLVRAGFAQDKDGTP-LFKYDPCGSEAFWDKQSIARNGEGLRLFVDKNGQVWTEDQI 78 >UniRef50_Q9XG34 Cluster: 26S proteasome IOTA SU; n=1; Guillardia theta|Rep: 26S proteasome IOTA SU - Guillardia theta (Cryptomonas phi) Length = 237 Score = 32.7 bits (71), Expect = 8.3 Identities = 31/144 (21%), Positives = 51/144 (35%) Frame = +3 Query: 93 FSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDDHV 272 F+P G + Q+EYA + +KGS K E I LDD Sbjct: 10 FAPSGRIFQIEYAVKK-KKGSICIGIKNNSFLIFLLYKSQ--NSSSESNESDIIFLDDKT 66 Query: 273 VMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFGI 452 GL D I + ++ + Y+++ I Q T + RP Sbjct: 67 GCLCNGLAIDVYEQIEEIKNIFFNYYSQYRSKIQTSYLSKLITFKNQYLTHYSFSRPRST 126 Query: 453 SCLIGGFDYDGSPHLFQTEPSGIY 524 + +I D + LF+ + +G + Sbjct: 127 NLIIFNLDNELGGQLFKGDNTGSF 150 >UniRef50_Q8T915 Cluster: AT05866p; n=1; Drosophila melanogaster|Rep: AT05866p - Drosophila melanogaster (Fruit fly) Length = 322 Score = 32.7 bits (71), Expect = 8.3 Identities = 33/139 (23%), Positives = 55/139 (39%) Frame = +3 Query: 234 RTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQ 413 +T RKI L ++ A AG D + L+ + + + H++ + ++Q Sbjct: 78 KTCRKIIELQANIFAAGAGTARDTKALVELTRAQLELHRMNTGFRKVPVCCANQM--IRQ 135 Query: 414 KYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 593 + NG +IGG D G+ HLF T G + G + LE + Sbjct: 136 LLFRFNGN--IDADMIIGGADNTGA-HLFCTRSDGSTDTAPFTSIGSGYQVSMSILESRW 192 Query: 594 TADEVATENGAVKLAIRAL 650 + D +E A LA A+ Sbjct: 193 SED--LSEESACALACDAV 209 >UniRef50_Q8T8U1 Cluster: Proteasome subunit beta type; n=1; Drosophila melanogaster|Rep: Proteasome subunit beta type - Drosophila melanogaster (Fruit fly) Length = 215 Score = 32.7 bits (71), Expect = 8.3 Identities = 32/132 (24%), Positives = 52/132 (39%) Frame = +3 Query: 207 KSVAKLQEERTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYI 386 KS L +E VRK + D+ +M+ AG D + +K+T +T+ Sbjct: 23 KSAMWLDDE--VRKTHRISDYCMMSTAGDGGDCLKFSDFILRNMDLYKITNGYDLTVRGA 80 Query: 387 TRYIAGLKQKYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKT 566 +I Y +S+ F +S L+GG+D P L + G + G + Sbjct: 81 VHFIRRHLSAYLKSDCT--FQVSLLVGGYDLTSGPELHYIDYLGNSVPVRYGGHGAAMNF 138 Query: 567 VREFLEKNYTAD 602 LE+ Y D Sbjct: 139 CTPILEEFYKPD 150 >UniRef50_Q22MS9 Cluster: Proteasome subunit beta type; n=2; Oligohymenophorea|Rep: Proteasome subunit beta type - Tetrahymena thermophila SB210 Length = 227 Score = 32.7 bits (71), Expect = 8.3 Identities = 24/138 (17%), Positives = 60/138 (43%), Gaps = 1/138 (0%) Frame = +3 Query: 231 ERTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLK 410 +R K+ L + + +G AD + L + + H + ++ T++ + + L Sbjct: 53 DRAQDKVDYLHERIYCLRSGSAADTQTLCSYVRYYLDVHSMELQRRPTVKTAAKLFSNLI 112 Query: 411 QKYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKN 590 +Y Q N + ++ G D + P ++ +PSG + + G + + +++ N Sbjct: 113 YQY-QDN----LSAAVIVAGIDDNEGPSIYACQPSGSCIKQQVAIGGSGSGFIFSYVDAN 167 Query: 591 YTAD-EVATENGAVKLAI 641 + + ++ + VK A+ Sbjct: 168 FRPNMDLESAKKLVKTAL 185 >UniRef50_Q59F72 Cluster: Proteasome alpha 6 subunit variant; n=1; Homo sapiens|Rep: Proteasome alpha 6 subunit variant - Homo sapiens (Human) Length = 80 Score = 32.7 bits (71), Expect = 8.3 Identities = 14/46 (30%), Positives = 24/46 (52%) Frame = +3 Query: 450 ISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 587 + ++ G D + P +++ +P+G Y +KA A G FLEK Sbjct: 7 LGMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEK 52 >UniRef50_Q5A9K1 Cluster: Possible intermediate filament protein Mdm1p; n=2; Candida albicans|Rep: Possible intermediate filament protein Mdm1p - Candida albicans (Yeast) Length = 1032 Score = 32.7 bits (71), Expect = 8.3 Identities = 12/27 (44%), Positives = 17/27 (62%) Frame = -3 Query: 479 IVESSYQTRNTKWSTTIALSIFLFETC 399 ++ S YQ NT+ + L IF+FETC Sbjct: 960 VIRSLYQQSNTRQEAKVLLEIFIFETC 986 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 625,407,599 Number of Sequences: 1657284 Number of extensions: 12291613 Number of successful extensions: 29420 Number of sequences better than 10.0: 159 Number of HSP's better than 10.0 without gapping: 28423 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 29306 length of database: 575,637,011 effective HSP length: 98 effective length of database: 413,223,179 effective search space used: 51652897375 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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