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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Nnor0488
         (717 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC066650-1|AAH66650.1|  874|Homo sapiens coatomer protein comple...   277   4e-74
AF100756-1|AAD43020.1|  874|Homo sapiens coat protein gamma-cop ...   277   4e-74
AB047846-1|BAB17657.1|  874|Homo sapiens gamma1-COP protein.          277   4e-74
BC110796-1|AAI10797.1|  726|Homo sapiens COPG2 protein protein.       264   2e-70
AF207598-1|AAF19433.1|  871|Homo sapiens coat protein gamma2-COP...   264   2e-70
AF157833-1|AAF14271.1|  871|Homo sapiens nonclathrin coat protei...   264   2e-70
AB047847-1|BAB17658.1|  871|Homo sapiens gamma2-COP protein.          264   2e-70
BC017443-1|AAH17443.2|  865|Homo sapiens COPG2 protein protein.       264   3e-70
AK022934-1|BAB14315.1|  799|Homo sapiens protein ( Homo sapiens ...   177   2e-44
BC020498-1|AAH20498.2|  699|Homo sapiens COPG protein protein.         69   1e-11
BC014146-1|AAH14146.1|  739|Homo sapiens adaptor-related protein...    42   0.002
AL137856-9|CAI19074.1|  262|Homo sapiens adaptor-related protein...    42   0.002
AL137856-5|CAI19072.1|  739|Homo sapiens adaptor-related protein...    42   0.002
AF092094-1|AAD20448.1|  739|Homo sapiens AP-4 adaptor complex be...    42   0.002
AB209817-1|BAD93054.1|  771|Homo sapiens adaptor-related protein...    42   0.002
U91931-1|AAD03778.1| 1093|Homo sapiens AP-3 complex beta3A subun...    38   0.027
U81504-1|AAB61638.1| 1094|Homo sapiens beta-3A-adaptin subunit o...    38   0.027
BC038444-1|AAH38444.1| 1094|Homo sapiens adaptor-related protein...    38   0.027
AY623424-1|AAT49048.1|  800|Homo sapiens adaptor-related protein...    38   0.027
U37673-1|AAC50219.1| 1081|Homo sapiens beta-NAP protein.               38   0.036
BC093739-1|AAH93739.1| 1082|Homo sapiens adaptor-related protein...    38   0.036
AF022152-1|AAB71894.1| 1082|Homo sapiens AP-3 complex beta3B sub...    38   0.036
U72395-1|AAB68948.1|  890|Homo sapiens MIP protein.                    33   1.4  
U72069-1|AAB58254.1|  890|Homo sapiens karyopherin beta2 protein.      33   1.4  
U70322-1|AAC50723.1|  890|Homo sapiens transportin protein.            33   1.4  
BC040340-1|AAH40340.1|  890|Homo sapiens transportin 1 protein.        33   1.4  
BC072420-1|AAH72420.1|  887|Homo sapiens transportin 2 (importin...    32   2.4  
AF007748-1|AAB71349.1|  887|Homo sapiens karyopherin beta2b homo...    32   2.4  
AB210011-1|BAE06093.1| 1051|Homo sapiens TNPO2 variant protein p...    32   2.4  
AY971956-1|AAY46814.1| 1892|Homo sapiens abnormal spindle-like m...    30   9.5  
AY367065-1|AAR12641.1| 3477|Homo sapiens abnormal spindle-like m...    30   9.5  
AY101201-1|AAM48745.1|  583|Homo sapiens abnormal spindle protein.     30   9.5  
AY099893-1|AAM44122.1|  825|Homo sapiens abnormal spindle protei...    30   9.5  
AY099891-1|AAM44120.1|  826|Homo sapiens abnormal spindle protei...    30   9.5  
AL353809-5|CAH72552.1| 3477|Homo sapiens asp (abnormal spindle) ...    30   9.5  
AF509326-1|AAN40011.1| 3477|Homo sapiens abnormal spindles protein.    30   9.5  

>BC066650-1|AAH66650.1|  874|Homo sapiens coatomer protein complex,
           subunit gamma protein.
          Length = 874

 Score =  277 bits (678), Expect = 4e-74
 Identities = 137/230 (59%), Positives = 170/230 (73%), Gaps = 4/230 (1%)
 Frame = +2

Query: 38  MKARRDGKEEDS----NVFQNLDKTTLLQEARYFNSTPVHPRKCIHILTKILYLLNQGEE 205
           M  + D K+E+S    N FQ+L+K+ +LQEAR FN TP++PRKC HILTKILYL+NQGE 
Sbjct: 1   MLKKFDKKDEESGGGSNPFQHLEKSAVLQEARVFNETPINPRKCAHILTKILYLINQGEH 60

Query: 206 LTTQEATDIFFATTKLFQSKDVVLRRLVYLCIKELSPMAQDVIIVTSSLTKDMTGKDDEY 385
           L T EAT+ FFA TKLFQS D  LRR+ YL IKE+S +A+DVIIVTSSLTKDMTGK+D Y
Sbjct: 61  LGTTEATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAEDVIIVTSSLTKDMTGKEDNY 120

Query: 386 RPAAIRALCSITDSTMLQAIERYMKQAIVDKNPXXXXXXXXXXXXXXXXXPDLVRRWINE 565
           R  A+RALC ITDSTMLQAIERYMKQAIVDK P                  D+V+RW+NE
Sbjct: 121 RGPAVRALCQITDSTMLQAIERYMKQAIVDKVPSVSSSALVSSLHLLKCSFDVVKRWVNE 180

Query: 566 AQEAMTSDHVMVSYHALAVVAGARRNDRLSTVKLITKLARTPVRSPYTLC 715
           AQEA +SD++MV YHAL ++   R+NDRL+  K+I+K+ R  ++SP+  C
Sbjct: 181 AQEAASSDNIMVQYHALGLLYHVRKNDRLAVNKMISKVTRHGLKSPFAYC 230


>AF100756-1|AAD43020.1|  874|Homo sapiens coat protein gamma-cop
           protein.
          Length = 874

 Score =  277 bits (678), Expect = 4e-74
 Identities = 137/230 (59%), Positives = 170/230 (73%), Gaps = 4/230 (1%)
 Frame = +2

Query: 38  MKARRDGKEEDS----NVFQNLDKTTLLQEARYFNSTPVHPRKCIHILTKILYLLNQGEE 205
           M  + D K+E+S    N FQ+L+K+ +LQEAR FN TP++PRKC HILTKILYL+NQGE 
Sbjct: 1   MLKKFDKKDEESGGGSNPFQHLEKSAVLQEARVFNETPINPRKCAHILTKILYLINQGEH 60

Query: 206 LTTQEATDIFFATTKLFQSKDVVLRRLVYLCIKELSPMAQDVIIVTSSLTKDMTGKDDEY 385
           L T EAT+ FFA TKLFQS D  LRR+ YL IKE+S +A+DVIIVTSSLTKDMTGK+D Y
Sbjct: 61  LGTTEATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAEDVIIVTSSLTKDMTGKEDNY 120

Query: 386 RPAAIRALCSITDSTMLQAIERYMKQAIVDKNPXXXXXXXXXXXXXXXXXPDLVRRWINE 565
           R  A+RALC ITDSTMLQAIERYMKQAIVDK P                  D+V+RW+NE
Sbjct: 121 RGPAVRALCQITDSTMLQAIERYMKQAIVDKVPSVSSSALVSSLHLLKCSFDVVKRWVNE 180

Query: 566 AQEAMTSDHVMVSYHALAVVAGARRNDRLSTVKLITKLARTPVRSPYTLC 715
           AQEA +SD++MV YHAL ++   R+NDRL+  K+I+K+ R  ++SP+  C
Sbjct: 181 AQEAASSDNIMVQYHALGLLYHVRKNDRLAVNKMISKVTRHGLKSPFAYC 230


>AB047846-1|BAB17657.1|  874|Homo sapiens gamma1-COP protein.
          Length = 874

 Score =  277 bits (678), Expect = 4e-74
 Identities = 137/230 (59%), Positives = 170/230 (73%), Gaps = 4/230 (1%)
 Frame = +2

Query: 38  MKARRDGKEEDS----NVFQNLDKTTLLQEARYFNSTPVHPRKCIHILTKILYLLNQGEE 205
           M  + D K+E+S    N FQ+L+K+ +LQEAR FN TP++PRKC HILTKILYL+NQGE 
Sbjct: 1   MLKKFDKKDEESGGGSNPFQHLEKSAVLQEARVFNETPINPRKCAHILTKILYLINQGEH 60

Query: 206 LTTQEATDIFFATTKLFQSKDVVLRRLVYLCIKELSPMAQDVIIVTSSLTKDMTGKDDEY 385
           L T EAT+ FFA TKLFQS D  LRR+ YL IKE+S +A+DVIIVTSSLTKDMTGK+D Y
Sbjct: 61  LGTTEATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAEDVIIVTSSLTKDMTGKEDNY 120

Query: 386 RPAAIRALCSITDSTMLQAIERYMKQAIVDKNPXXXXXXXXXXXXXXXXXPDLVRRWINE 565
           R  A+RALC ITDSTMLQAIERYMKQAIVDK P                  D+V+RW+NE
Sbjct: 121 RGPAVRALCQITDSTMLQAIERYMKQAIVDKVPSVSSSALVSSLHLLKCSFDVVKRWVNE 180

Query: 566 AQEAMTSDHVMVSYHALAVVAGARRNDRLSTVKLITKLARTPVRSPYTLC 715
           AQEA +SD++MV YHAL ++   R+NDRL+  K+I+K+ R  ++SP+  C
Sbjct: 181 AQEAASSDNIMVQYHALGLLYHVRKNDRLAVNKMISKVTRHGLKSPFAYC 230


>BC110796-1|AAI10797.1|  726|Homo sapiens COPG2 protein protein.
          Length = 726

 Score =  264 bits (647), Expect = 2e-70
 Identities = 130/225 (57%), Positives = 164/225 (72%), Gaps = 4/225 (1%)
 Frame = +2

Query: 53  DGKEEDS----NVFQNLDKTTLLQEARYFNSTPVHPRKCIHILTKILYLLNQGEELTTQE 220
           D K+E+S    N FQ+L+K+ +LQEAR FN TP++PR+C+HILTKILYLLNQGE   T E
Sbjct: 6   DKKDEESGSGSNPFQHLEKSAVLQEARIFNETPINPRRCLHILTKILYLLNQGEHFGTTE 65

Query: 221 ATDIFFATTKLFQSKDVVLRRLVYLCIKELSPMAQDVIIVTSSLTKDMTGKDDEYRPAAI 400
           AT+ FFA T+LFQS D  LRR+ YL IKE++ +++DVIIVTSSLTKDMTGK+D YR  AI
Sbjct: 66  ATEAFFAMTRLFQSNDQTLRRMCYLTIKEMATISEDVIIVTSSLTKDMTGKEDVYRGPAI 125

Query: 401 RALCSITDSTMLQAIERYMKQAIVDKNPXXXXXXXXXXXXXXXXXPDLVRRWINEAQEAM 580
           RALC ITD TMLQAIERYMKQAIVDK                    D+V+RWINEAQEA 
Sbjct: 126 RALCRITDGTMLQAIERYMKQAIVDKVSSVSSSALVSSLHMMKISYDVVKRWINEAQEAA 185

Query: 581 TSDHVMVSYHALAVVAGARRNDRLSTVKLITKLARTPVRSPYTLC 715
           +SD++MV YHAL V+   R+NDRL+  K++ K  ++ ++S +  C
Sbjct: 186 SSDNIMVQYHALGVLYHLRKNDRLAVSKMLNKFTKSGLKSQFAYC 230


>AF207598-1|AAF19433.1|  871|Homo sapiens coat protein gamma2-COP
           protein.
          Length = 871

 Score =  264 bits (647), Expect = 2e-70
 Identities = 130/225 (57%), Positives = 164/225 (72%), Gaps = 4/225 (1%)
 Frame = +2

Query: 53  DGKEEDS----NVFQNLDKTTLLQEARYFNSTPVHPRKCIHILTKILYLLNQGEELTTQE 220
           D K+E+S    N FQ+L+K+ +LQEAR FN TP++PR+C+HILTKILYLLNQGE   T E
Sbjct: 6   DKKDEESGSGSNPFQHLEKSAVLQEARIFNETPINPRRCLHILTKILYLLNQGEHFGTTE 65

Query: 221 ATDIFFATTKLFQSKDVVLRRLVYLCIKELSPMAQDVIIVTSSLTKDMTGKDDEYRPAAI 400
           AT+ FFA T+LFQS D  LRR+ YL IKE++ +++DVIIVTSSLTKDMTGK+D YR  AI
Sbjct: 66  ATEAFFAMTRLFQSNDQTLRRMCYLTIKEMATISEDVIIVTSSLTKDMTGKEDVYRGPAI 125

Query: 401 RALCSITDSTMLQAIERYMKQAIVDKNPXXXXXXXXXXXXXXXXXPDLVRRWINEAQEAM 580
           RALC ITD TMLQAIERYMKQAIVDK                    D+V+RWINEAQEA 
Sbjct: 126 RALCRITDGTMLQAIERYMKQAIVDKVSSVSSSALVSSLHMMKISYDVVKRWINEAQEAA 185

Query: 581 TSDHVMVSYHALAVVAGARRNDRLSTVKLITKLARTPVRSPYTLC 715
           +SD++MV YHAL V+   R+NDRL+  K++ K  ++ ++S +  C
Sbjct: 186 SSDNIMVQYHALGVLYHLRKNDRLAVSKMLNKFTKSGLKSQFAYC 230


>AF157833-1|AAF14271.1|  871|Homo sapiens nonclathrin coat protein
           gamma2-COP protein.
          Length = 871

 Score =  264 bits (647), Expect = 2e-70
 Identities = 130/225 (57%), Positives = 164/225 (72%), Gaps = 4/225 (1%)
 Frame = +2

Query: 53  DGKEEDS----NVFQNLDKTTLLQEARYFNSTPVHPRKCIHILTKILYLLNQGEELTTQE 220
           D K+E+S    N FQ+L+K+ +LQEAR FN TP++PR+C+HILTKILYLLNQGE   T E
Sbjct: 6   DKKDEESGSGSNPFQHLEKSAVLQEARIFNETPINPRRCLHILTKILYLLNQGEHFGTTE 65

Query: 221 ATDIFFATTKLFQSKDVVLRRLVYLCIKELSPMAQDVIIVTSSLTKDMTGKDDEYRPAAI 400
           AT+ FFA T+LFQS D  LRR+ YL IKE++ +++DVIIVTSSLTKDMTGK+D YR  AI
Sbjct: 66  ATEAFFAMTRLFQSNDQTLRRMCYLTIKEMATISEDVIIVTSSLTKDMTGKEDVYRGPAI 125

Query: 401 RALCSITDSTMLQAIERYMKQAIVDKNPXXXXXXXXXXXXXXXXXPDLVRRWINEAQEAM 580
           RALC ITD TMLQAIERYMKQAIVDK                    D+V+RWINEAQEA 
Sbjct: 126 RALCRITDGTMLQAIERYMKQAIVDKVSSVSSSALVSSLHMMKISYDVVKRWINEAQEAA 185

Query: 581 TSDHVMVSYHALAVVAGARRNDRLSTVKLITKLARTPVRSPYTLC 715
           +SD++MV YHAL V+   R+NDRL+  K++ K  ++ ++S +  C
Sbjct: 186 SSDNIMVQYHALGVLYHLRKNDRLAVSKMLNKFTKSGLKSQFAYC 230


>AB047847-1|BAB17658.1|  871|Homo sapiens gamma2-COP protein.
          Length = 871

 Score =  264 bits (647), Expect = 2e-70
 Identities = 130/225 (57%), Positives = 164/225 (72%), Gaps = 4/225 (1%)
 Frame = +2

Query: 53  DGKEEDS----NVFQNLDKTTLLQEARYFNSTPVHPRKCIHILTKILYLLNQGEELTTQE 220
           D K+E+S    N FQ+L+K+ +LQEAR FN TP++PR+C+HILTKILYLLNQGE   T E
Sbjct: 6   DKKDEESGSGSNPFQHLEKSAVLQEARIFNETPINPRRCLHILTKILYLLNQGEHFGTTE 65

Query: 221 ATDIFFATTKLFQSKDVVLRRLVYLCIKELSPMAQDVIIVTSSLTKDMTGKDDEYRPAAI 400
           AT+ FFA T+LFQS D  LRR+ YL IKE++ +++DVIIVTSSLTKDMTGK+D YR  AI
Sbjct: 66  ATEAFFAMTRLFQSNDQTLRRMCYLTIKEMATISEDVIIVTSSLTKDMTGKEDVYRGPAI 125

Query: 401 RALCSITDSTMLQAIERYMKQAIVDKNPXXXXXXXXXXXXXXXXXPDLVRRWINEAQEAM 580
           RALC ITD TMLQAIERYMKQAIVDK                    D+V+RWINEAQEA 
Sbjct: 126 RALCRITDGTMLQAIERYMKQAIVDKVSSVSSSALVSSLHMMKISYDVVKRWINEAQEAA 185

Query: 581 TSDHVMVSYHALAVVAGARRNDRLSTVKLITKLARTPVRSPYTLC 715
           +SD++MV YHAL V+   R+NDRL+  K++ K  ++ ++S +  C
Sbjct: 186 SSDNIMVQYHALGVLYHLRKNDRLAVSKMLNKFTKSGLKSQFAYC 230


>BC017443-1|AAH17443.2|  865|Homo sapiens COPG2 protein protein.
          Length = 865

 Score =  264 bits (646), Expect = 3e-70
 Identities = 127/215 (59%), Positives = 159/215 (73%)
 Frame = +2

Query: 71  SNVFQNLDKTTLLQEARYFNSTPVHPRKCIHILTKILYLLNQGEELTTQEATDIFFATTK 250
           SN FQ+L+K+ +LQEAR FN TP++PR+C+HILTKILYLLNQGE   T EAT+ FFA T+
Sbjct: 10  SNPFQHLEKSAVLQEARIFNETPINPRRCLHILTKILYLLNQGEHFGTTEATEAFFAMTR 69

Query: 251 LFQSKDVVLRRLVYLCIKELSPMAQDVIIVTSSLTKDMTGKDDEYRPAAIRALCSITDST 430
           LFQS D  LRR+ YL IKE++ +++DVIIVTSSLTKDMTGK+D YR  AIRALC ITD T
Sbjct: 70  LFQSNDQTLRRMCYLTIKEMATISEDVIIVTSSLTKDMTGKEDVYRGPAIRALCRITDGT 129

Query: 431 MLQAIERYMKQAIVDKNPXXXXXXXXXXXXXXXXXPDLVRRWINEAQEAMTSDHVMVSYH 610
           MLQAIERYMKQAIVDK                    D+V+RWINEAQEA +SD++MV YH
Sbjct: 130 MLQAIERYMKQAIVDKVSSVSSSALVSSLHMMKISYDVVKRWINEAQEAASSDNIMVQYH 189

Query: 611 ALAVVAGARRNDRLSTVKLITKLARTPVRSPYTLC 715
           AL V+   R+NDRL+  K++ K  ++ ++S +  C
Sbjct: 190 ALGVLYHLRKNDRLAVSKMLNKFTKSGLKSQFAYC 224


>AK022934-1|BAB14315.1|  799|Homo sapiens protein ( Homo sapiens
           cDNA FLJ12872 fis, clone NT2RP2003760, highly similar to
           COATOMER GAMMA SUBUNIT. ).
          Length = 799

 Score =  177 bits (432), Expect = 2e-44
 Identities = 88/157 (56%), Positives = 110/157 (70%)
 Frame = +2

Query: 245 TKLFQSKDVVLRRLVYLCIKELSPMAQDVIIVTSSLTKDMTGKDDEYRPAAIRALCSITD 424
           T+LFQS D  LRR+ YL IKE++ +++DVIIVTSSLTKDMTGK+D YR  AIRALC ITD
Sbjct: 2   TRLFQSNDQTLRRMCYLTIKEMATISEDVIIVTSSLTKDMTGKEDVYRGPAIRALCRITD 61

Query: 425 STMLQAIERYMKQAIVDKNPXXXXXXXXXXXXXXXXXPDLVRRWINEAQEAMTSDHVMVS 604
            TMLQAIERYMKQAIVDK                    D+V+RWINEAQEA +SD++MV 
Sbjct: 62  GTMLQAIERYMKQAIVDKVSSVSSSALVSSLHMMKISYDVVKRWINEAQEAASSDNIMVQ 121

Query: 605 YHALAVVAGARRNDRLSTVKLITKLARTPVRSPYTLC 715
           YHAL V+   R+NDRL+  K++ K  ++  +S +  C
Sbjct: 122 YHALGVLYHLRKNDRLAVSKMLNKFTKSGPKSQFAYC 158


>BC020498-1|AAH20498.2|  699|Homo sapiens COPG protein protein.
          Length = 699

 Score = 69.3 bits (162), Expect = 1e-11
 Identities = 28/55 (50%), Positives = 42/55 (76%)
 Frame = +2

Query: 551 RWINEAQEAMTSDHVMVSYHALAVVAGARRNDRLSTVKLITKLARTPVRSPYTLC 715
           RW+NEAQEA +SD++MV YHAL ++   R+NDRL+  K+I+K+ R  ++SP+  C
Sbjct: 1   RWVNEAQEAASSDNIMVQYHALGLLYHVRKNDRLAVNKMISKVTRHGLKSPFAYC 55


>BC014146-1|AAH14146.1|  739|Homo sapiens adaptor-related protein
           complex 4, beta 1 subunit protein.
          Length = 739

 Score = 42.3 bits (95), Expect = 0.002
 Identities = 23/106 (21%), Positives = 59/106 (55%), Gaps = 1/106 (0%)
 Frame = +2

Query: 161 HILTKILYLLNQGEELTTQEATDIFFATTKLFQSKDVVLRRLVYLCIKELSPMAQDV-II 337
           +++ +++  + QG +++      +F    K   + D+V ++LVYL +   +P+  D+ ++
Sbjct: 31  NVIQRVIRYMTQGLDMS-----GVFMEMVKASATVDIVQKKLVYLYMCTYAPLKPDLALL 85

Query: 338 VTSSLTKDMTGKDDEYRPAAIRALCSITDSTMLQAIERYMKQAIVD 475
             ++L KD +  +   R  A+R++CS+     +  ++ Y++Q I++
Sbjct: 86  AINTLCKDCSDPNPMVRGLALRSMCSL----RMPGVQEYIQQPILN 127


>AL137856-9|CAI19074.1|  262|Homo sapiens adaptor-related protein
           complex 4, beta 1 subunit protein.
          Length = 262

 Score = 42.3 bits (95), Expect = 0.002
 Identities = 23/106 (21%), Positives = 59/106 (55%), Gaps = 1/106 (0%)
 Frame = +2

Query: 161 HILTKILYLLNQGEELTTQEATDIFFATTKLFQSKDVVLRRLVYLCIKELSPMAQDV-II 337
           +++ +++  + QG +++      +F    K   + D+V ++LVYL +   +P+  D+ ++
Sbjct: 31  NVIQRVIRYMTQGLDMS-----GVFMEMVKASATVDIVQKKLVYLYMCTYAPLKPDLALL 85

Query: 338 VTSSLTKDMTGKDDEYRPAAIRALCSITDSTMLQAIERYMKQAIVD 475
             ++L KD +  +   R  A+R++CS+     +  ++ Y++Q I++
Sbjct: 86  AINTLCKDCSDPNPMVRGLALRSMCSL----RMPGVQEYIQQPILN 127


>AL137856-5|CAI19072.1|  739|Homo sapiens adaptor-related protein
           complex 4, beta 1 subunit protein.
          Length = 739

 Score = 42.3 bits (95), Expect = 0.002
 Identities = 23/106 (21%), Positives = 59/106 (55%), Gaps = 1/106 (0%)
 Frame = +2

Query: 161 HILTKILYLLNQGEELTTQEATDIFFATTKLFQSKDVVLRRLVYLCIKELSPMAQDV-II 337
           +++ +++  + QG +++      +F    K   + D+V ++LVYL +   +P+  D+ ++
Sbjct: 31  NVIQRVIRYMTQGLDMS-----GVFMEMVKASATVDIVQKKLVYLYMCTYAPLKPDLALL 85

Query: 338 VTSSLTKDMTGKDDEYRPAAIRALCSITDSTMLQAIERYMKQAIVD 475
             ++L KD +  +   R  A+R++CS+     +  ++ Y++Q I++
Sbjct: 86  AINTLCKDCSDPNPMVRGLALRSMCSL----RMPGVQEYIQQPILN 127


>AF092094-1|AAD20448.1|  739|Homo sapiens AP-4 adaptor complex beta4
           subunit protein.
          Length = 739

 Score = 42.3 bits (95), Expect = 0.002
 Identities = 23/106 (21%), Positives = 59/106 (55%), Gaps = 1/106 (0%)
 Frame = +2

Query: 161 HILTKILYLLNQGEELTTQEATDIFFATTKLFQSKDVVLRRLVYLCIKELSPMAQDV-II 337
           +++ +++  + QG +++      +F    K   + D+V ++LVYL +   +P+  D+ ++
Sbjct: 31  NVIQRVIRYMTQGLDMS-----GVFMEMVKASATVDIVQKKLVYLYMCTYAPLKPDLALL 85

Query: 338 VTSSLTKDMTGKDDEYRPAAIRALCSITDSTMLQAIERYMKQAIVD 475
             ++L KD +  +   R  A+R++CS+     +  ++ Y++Q I++
Sbjct: 86  AINTLCKDCSDPNPMVRGLALRSMCSL----RMPGVQEYIQQPILN 127


>AB209817-1|BAD93054.1|  771|Homo sapiens adaptor-related protein
           complex 4, beta 1 subunit variant protein.
          Length = 771

 Score = 42.3 bits (95), Expect = 0.002
 Identities = 23/106 (21%), Positives = 59/106 (55%), Gaps = 1/106 (0%)
 Frame = +2

Query: 161 HILTKILYLLNQGEELTTQEATDIFFATTKLFQSKDVVLRRLVYLCIKELSPMAQDV-II 337
           +++ +++  + QG +++      +F    K   + D+V ++LVYL +   +P+  D+ ++
Sbjct: 63  NVIQRVIRYMTQGLDMS-----GVFMEMVKASATVDIVQKKLVYLYMCTYAPLKPDLALL 117

Query: 338 VTSSLTKDMTGKDDEYRPAAIRALCSITDSTMLQAIERYMKQAIVD 475
             ++L KD +  +   R  A+R++CS+     +  ++ Y++Q I++
Sbjct: 118 AINTLCKDCSDPNPMVRGLALRSMCSL----RMPGVQEYIQQPILN 159


>U91931-1|AAD03778.1| 1093|Homo sapiens AP-3 complex beta3A subunit
           protein.
          Length = 1093

 Score = 38.3 bits (85), Expect = 0.027
 Identities = 22/91 (24%), Positives = 50/91 (54%), Gaps = 1/91 (1%)
 Frame = +2

Query: 215 QEATDIFFATTKLFQSKDVVLRRLVYLCIKELSPMAQDVIIVT-SSLTKDMTGKDDEYRP 391
           + A+++F A  K   SK++ +++LVY+ +   +   QD+ +++ S+  + +   +   R 
Sbjct: 74  KNASELFPAVVKNVASKNIEIKKLVYVYLVRYAEEQQDLALLSISTFQRALKDPNQLIRA 133

Query: 392 AAIRALCSITDSTMLQAIERYMKQAIVDKNP 484
           +A+R L SI    ++  +   +K+A  D +P
Sbjct: 134 SALRVLSSIRVPIIVPIMMLAIKEASADLSP 164


>U81504-1|AAB61638.1| 1094|Homo sapiens beta-3A-adaptin subunit of
           the AP-3 complex protein.
          Length = 1094

 Score = 38.3 bits (85), Expect = 0.027
 Identities = 22/91 (24%), Positives = 50/91 (54%), Gaps = 1/91 (1%)
 Frame = +2

Query: 215 QEATDIFFATTKLFQSKDVVLRRLVYLCIKELSPMAQDVIIVT-SSLTKDMTGKDDEYRP 391
           + A+++F A  K   SK++ +++LVY+ +   +   QD+ +++ S+  + +   +   R 
Sbjct: 74  KNASELFPAVVKNVASKNIEIKKLVYVYLVRYAEEQQDLALLSISTFQRALKDPNQLIRA 133

Query: 392 AAIRALCSITDSTMLQAIERYMKQAIVDKNP 484
           +A+R L SI    ++  +   +K+A  D +P
Sbjct: 134 SALRVLSSIRVPIIVPIMMLAIKEASADLSP 164


>BC038444-1|AAH38444.1| 1094|Homo sapiens adaptor-related protein
           complex 3, beta 1 subunit protein.
          Length = 1094

 Score = 38.3 bits (85), Expect = 0.027
 Identities = 22/91 (24%), Positives = 50/91 (54%), Gaps = 1/91 (1%)
 Frame = +2

Query: 215 QEATDIFFATTKLFQSKDVVLRRLVYLCIKELSPMAQDVIIVT-SSLTKDMTGKDDEYRP 391
           + A+++F A  K   SK++ +++LVY+ +   +   QD+ +++ S+  + +   +   R 
Sbjct: 74  KNASELFPAVVKNVASKNIEIKKLVYVYLVRYAEEQQDLALLSISTFQRALKDPNQLIRA 133

Query: 392 AAIRALCSITDSTMLQAIERYMKQAIVDKNP 484
           +A+R L SI    ++  +   +K+A  D +P
Sbjct: 134 SALRVLSSIRVPIIVPIMMLAIKEASADLSP 164


>AY623424-1|AAT49048.1|  800|Homo sapiens adaptor-related protein
           complex 3 beta 1 subunit protein.
          Length = 800

 Score = 38.3 bits (85), Expect = 0.027
 Identities = 22/91 (24%), Positives = 50/91 (54%), Gaps = 1/91 (1%)
 Frame = +2

Query: 215 QEATDIFFATTKLFQSKDVVLRRLVYLCIKELSPMAQDVIIVT-SSLTKDMTGKDDEYRP 391
           + A+++F A  K   SK++ +++LVY+ +   +   QD+ +++ S+  + +   +   R 
Sbjct: 74  KNASELFPAVVKNVASKNIEIKKLVYVYLVRYAEEQQDLALLSISTFQRALKDPNQLIRA 133

Query: 392 AAIRALCSITDSTMLQAIERYMKQAIVDKNP 484
           +A+R L SI    ++  +   +K+A  D +P
Sbjct: 134 SALRVLSSIRVPIIVPIMMLAIKEASADLSP 164


>U37673-1|AAC50219.1| 1081|Homo sapiens beta-NAP protein.
          Length = 1081

 Score = 37.9 bits (84), Expect = 0.036
 Identities = 22/91 (24%), Positives = 49/91 (53%), Gaps = 1/91 (1%)
 Frame = +2

Query: 215 QEATDIFFATTKLFQSKDVVLRRLVYLCIKELSPMAQDVIIVT-SSLTKDMTGKDDEYRP 391
           + A+D+F A  K    K++ +++LVY+ +   +   QD+ +++ S+  + +   +   R 
Sbjct: 69  KNASDLFPAVVKNVACKNIEVKKLVYVYLVRYAEEQQDLALLSISTFQRGLKDPNQLIRA 128

Query: 392 AAIRALCSITDSTMLQAIERYMKQAIVDKNP 484
           +A+R L SI    ++  +   +K+A  D +P
Sbjct: 129 SALRVLSSIRVPIIVPIMMLAIKEAASDMSP 159


>BC093739-1|AAH93739.1| 1082|Homo sapiens adaptor-related protein
           complex 3, beta 2 subunit protein.
          Length = 1082

 Score = 37.9 bits (84), Expect = 0.036
 Identities = 22/91 (24%), Positives = 49/91 (53%), Gaps = 1/91 (1%)
 Frame = +2

Query: 215 QEATDIFFATTKLFQSKDVVLRRLVYLCIKELSPMAQDVIIVT-SSLTKDMTGKDDEYRP 391
           + A+D+F A  K    K++ +++LVY+ +   +   QD+ +++ S+  + +   +   R 
Sbjct: 69  KNASDLFPAVVKNVACKNIEVKKLVYVYLVRYAEEQQDLALLSISTFQRGLKDPNQLIRA 128

Query: 392 AAIRALCSITDSTMLQAIERYMKQAIVDKNP 484
           +A+R L SI    ++  +   +K+A  D +P
Sbjct: 129 SALRVLSSIRVPIIVPIMMLAIKEAASDMSP 159


>AF022152-1|AAB71894.1| 1082|Homo sapiens AP-3 complex beta3B
           subunit protein.
          Length = 1082

 Score = 37.9 bits (84), Expect = 0.036
 Identities = 22/91 (24%), Positives = 49/91 (53%), Gaps = 1/91 (1%)
 Frame = +2

Query: 215 QEATDIFFATTKLFQSKDVVLRRLVYLCIKELSPMAQDVIIVT-SSLTKDMTGKDDEYRP 391
           + A+D+F A  K    K++ +++LVY+ +   +   QD+ +++ S+  + +   +   R 
Sbjct: 69  KNASDLFPAVVKNVACKNIEVKKLVYVYLVRYAEEQQDLALLSISTFQRGLKDPNQLIRA 128

Query: 392 AAIRALCSITDSTMLQAIERYMKQAIVDKNP 484
           +A+R L SI    ++  +   +K+A  D +P
Sbjct: 129 SALRVLSSIRVPIIVPIMMLAIKEAASDMSP 159


>U72395-1|AAB68948.1|  890|Homo sapiens MIP protein.
          Length = 890

 Score = 32.7 bits (71), Expect = 1.4
 Identities = 15/56 (26%), Positives = 34/56 (60%)
 Frame = +2

Query: 251 LFQSKDVVLRRLVYLCIKELSPMAQDVIIVTSSLTKDMTGKDDEYRPAAIRALCSI 418
           L ++  + + RL Y+C +E++PM Q  I    +  +++  +D+E + +A R +C++
Sbjct: 767 LLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNI--RDNEEKDSAFRGICTM 820


>U72069-1|AAB58254.1|  890|Homo sapiens karyopherin beta2 protein.
          Length = 890

 Score = 32.7 bits (71), Expect = 1.4
 Identities = 15/56 (26%), Positives = 34/56 (60%)
 Frame = +2

Query: 251 LFQSKDVVLRRLVYLCIKELSPMAQDVIIVTSSLTKDMTGKDDEYRPAAIRALCSI 418
           L ++  + + RL Y+C +E++PM Q  I    +  +++  +D+E + +A R +C++
Sbjct: 767 LLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNI--RDNEEKDSAFRGICTM 820


>U70322-1|AAC50723.1|  890|Homo sapiens transportin protein.
          Length = 890

 Score = 32.7 bits (71), Expect = 1.4
 Identities = 15/56 (26%), Positives = 34/56 (60%)
 Frame = +2

Query: 251 LFQSKDVVLRRLVYLCIKELSPMAQDVIIVTSSLTKDMTGKDDEYRPAAIRALCSI 418
           L ++  + + RL Y+C +E++PM Q  I    +  +++  +D+E + +A R +C++
Sbjct: 767 LLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNI--RDNEEKDSAFRGICTM 820


>BC040340-1|AAH40340.1|  890|Homo sapiens transportin 1 protein.
          Length = 890

 Score = 32.7 bits (71), Expect = 1.4
 Identities = 15/56 (26%), Positives = 34/56 (60%)
 Frame = +2

Query: 251 LFQSKDVVLRRLVYLCIKELSPMAQDVIIVTSSLTKDMTGKDDEYRPAAIRALCSI 418
           L ++  + + RL Y+C +E++PM Q  I    +  +++  +D+E + +A R +C++
Sbjct: 767 LLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNI--RDNEEKDSAFRGICTM 820


>BC072420-1|AAH72420.1|  887|Homo sapiens transportin 2 (importin 3,
           karyopherin beta 2b) protein.
          Length = 887

 Score = 31.9 bits (69), Expect = 2.4
 Identities = 15/54 (27%), Positives = 32/54 (59%)
 Frame = +2

Query: 251 LFQSKDVVLRRLVYLCIKELSPMAQDVIIVTSSLTKDMTGKDDEYRPAAIRALC 412
           L ++  + + RL Y+C +E++PM Q  I    +  +++  +D+E + +A R +C
Sbjct: 764 LLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNI--RDNEEKDSAFRGIC 815


>AF007748-1|AAB71349.1|  887|Homo sapiens karyopherin beta2b homolog
           protein.
          Length = 887

 Score = 31.9 bits (69), Expect = 2.4
 Identities = 15/54 (27%), Positives = 32/54 (59%)
 Frame = +2

Query: 251 LFQSKDVVLRRLVYLCIKELSPMAQDVIIVTSSLTKDMTGKDDEYRPAAIRALC 412
           L ++  + + RL Y+C +E++PM Q  I    +  +++  +D+E + +A R +C
Sbjct: 764 LLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNI--RDNEEKDSAFRGIC 815


>AB210011-1|BAE06093.1| 1051|Homo sapiens TNPO2 variant protein
            protein.
          Length = 1051

 Score = 31.9 bits (69), Expect = 2.4
 Identities = 15/54 (27%), Positives = 32/54 (59%)
 Frame = +2

Query: 251  LFQSKDVVLRRLVYLCIKELSPMAQDVIIVTSSLTKDMTGKDDEYRPAAIRALC 412
            L ++  + + RL Y+C +E++PM Q  I    +  +++  +D+E + +A R +C
Sbjct: 928  LLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNI--RDNEEKDSAFRGIC 979


>AY971956-1|AAY46814.1| 1892|Homo sapiens abnormal spindle-like
           microcephaly associated splice variant 1 protein.
          Length = 1892

 Score = 29.9 bits (64), Expect = 9.5
 Identities = 19/76 (25%), Positives = 38/76 (50%), Gaps = 5/76 (6%)
 Frame = +2

Query: 41  KARRDGKEEDSNVFQNLDKTTLLQEARYFNSTPVHP-----RKCIHILTKILYLLNQGEE 205
           K + DG  ED+NV   + + T ++E +  + +P  P     +K  ++ T I   ++  E+
Sbjct: 574 KRKSDGSMEDANVRVAITEHTEVREIKRIHFSPSEPKTSAVKKTKNVTTPISKRISNREK 633

Query: 206 LTTQEATDIFFATTKL 253
           L  ++ TD+    T +
Sbjct: 634 LNLKKKTDLSIFRTPI 649


>AY367065-1|AAR12641.1| 3477|Homo sapiens abnormal spindle-like
           microcephaly-associated protein protein.
          Length = 3477

 Score = 29.9 bits (64), Expect = 9.5
 Identities = 19/76 (25%), Positives = 38/76 (50%), Gaps = 5/76 (6%)
 Frame = +2

Query: 41  KARRDGKEEDSNVFQNLDKTTLLQEARYFNSTPVHP-----RKCIHILTKILYLLNQGEE 205
           K + DG  ED+NV   + + T ++E +  + +P  P     +K  ++ T I   ++  E+
Sbjct: 574 KRKSDGSMEDANVRVAITEHTEVREIKRIHFSPSEPKTSAVKKTKNVTTPISKRISNREK 633

Query: 206 LTTQEATDIFFATTKL 253
           L  ++ TD+    T +
Sbjct: 634 LNLKKKTDLSIFRTPI 649


>AY101201-1|AAM48745.1|  583|Homo sapiens abnormal spindle protein.
          Length = 583

 Score = 29.9 bits (64), Expect = 9.5
 Identities = 19/76 (25%), Positives = 38/76 (50%), Gaps = 5/76 (6%)
 Frame = +2

Query: 41  KARRDGKEEDSNVFQNLDKTTLLQEARYFNSTPVHP-----RKCIHILTKILYLLNQGEE 205
           K + DG  ED+NV   + + T ++E +  + +P  P     +K  ++ T I   ++  E+
Sbjct: 463 KRKSDGSMEDANVRVAITEHTEVREIKRIHFSPSEPKTSAVKKTKNVTTPISKRISNREK 522

Query: 206 LTTQEATDIFFATTKL 253
           L  ++ TD+    T +
Sbjct: 523 LNLKKKTDLSIFRTPI 538


>AY099893-1|AAM44122.1|  825|Homo sapiens abnormal spindle protein
           ASP protein.
          Length = 825

 Score = 29.9 bits (64), Expect = 9.5
 Identities = 19/76 (25%), Positives = 38/76 (50%), Gaps = 5/76 (6%)
 Frame = +2

Query: 41  KARRDGKEEDSNVFQNLDKTTLLQEARYFNSTPVHP-----RKCIHILTKILYLLNQGEE 205
           K + DG  ED+NV   + + T ++E +  + +P  P     +K  ++ T I   ++  E+
Sbjct: 168 KRKSDGSMEDANVRVAITEHTEVREIKRIHFSPSEPKTSAVKKTKNVTTPISKRISNREK 227

Query: 206 LTTQEATDIFFATTKL 253
           L  ++ TD+    T +
Sbjct: 228 LNLKKKTDLSIFRTPI 243


>AY099891-1|AAM44120.1|  826|Homo sapiens abnormal spindle protein
           ASP protein.
          Length = 826

 Score = 29.9 bits (64), Expect = 9.5
 Identities = 19/76 (25%), Positives = 38/76 (50%), Gaps = 5/76 (6%)
 Frame = +2

Query: 41  KARRDGKEEDSNVFQNLDKTTLLQEARYFNSTPVHP-----RKCIHILTKILYLLNQGEE 205
           K + DG  ED+NV   + + T ++E +  + +P  P     +K  ++ T I   ++  E+
Sbjct: 168 KRKSDGSMEDANVRVAITEHTEVREIKRIHFSPSEPKTSAVKKTKNVTTPISKRISNREK 227

Query: 206 LTTQEATDIFFATTKL 253
           L  ++ TD+    T +
Sbjct: 228 LNLKKKTDLSIFRTPI 243


>AL353809-5|CAH72552.1| 3477|Homo sapiens asp (abnormal spindle)
           homolog, microcephaly associated (Drosophila) protein.
          Length = 3477

 Score = 29.9 bits (64), Expect = 9.5
 Identities = 19/76 (25%), Positives = 38/76 (50%), Gaps = 5/76 (6%)
 Frame = +2

Query: 41  KARRDGKEEDSNVFQNLDKTTLLQEARYFNSTPVHP-----RKCIHILTKILYLLNQGEE 205
           K + DG  ED+NV   + + T ++E +  + +P  P     +K  ++ T I   ++  E+
Sbjct: 574 KRKSDGSMEDANVRVAITEHTEVREIKRIHFSPSEPKTSAVKKTKNVTTPISKRISNREK 633

Query: 206 LTTQEATDIFFATTKL 253
           L  ++ TD+    T +
Sbjct: 634 LNLKKKTDLSIFRTPI 649


>AF509326-1|AAN40011.1| 3477|Homo sapiens abnormal spindles protein.
          Length = 3477

 Score = 29.9 bits (64), Expect = 9.5
 Identities = 19/76 (25%), Positives = 38/76 (50%), Gaps = 5/76 (6%)
 Frame = +2

Query: 41  KARRDGKEEDSNVFQNLDKTTLLQEARYFNSTPVHP-----RKCIHILTKILYLLNQGEE 205
           K + DG  ED+NV   + + T ++E +  + +P  P     +K  ++ T I   ++  E+
Sbjct: 574 KRKSDGSMEDANVRVAITEHTEVREIKRIHFSPSEPKTSAVKKTKNVTTPISKRISNREK 633

Query: 206 LTTQEATDIFFATTKL 253
           L  ++ TD+    T +
Sbjct: 634 LNLKKKTDLSIFRTPI 649


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 105,000,728
Number of Sequences: 237096
Number of extensions: 2217942
Number of successful extensions: 4450
Number of sequences better than 10.0: 36
Number of HSP's better than 10.0 without gapping: 4333
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4441
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8399192100
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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