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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Nnor0486
         (759 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q2F664 Cluster: Phospholipid scramblase; n=1; Bombyx mo...   305   5e-82
UniRef50_UPI0000F2E10C Cluster: PREDICTED: similar to phospholip...    77   5e-13
UniRef50_A0PG75 Cluster: Phospholipid scramblase family memmber ...    73   6e-12
UniRef50_Q9NRQ2 Cluster: Phospholipid scramblase 4 (PL scramblas...    72   1e-11
UniRef50_Q9NRY7 Cluster: Phospholipid scramblase 2 (PL scramblas...    71   2e-11
UniRef50_O15162 Cluster: Phospholipid scramblase 1 (PL scramblas...    68   2e-10
UniRef50_Q7T1Q9 Cluster: Phospholipid scramblase 1; n=4; Euteleo...    67   5e-10
UniRef50_UPI0000D5613B Cluster: PREDICTED: similar to CG9084-PB;...    66   1e-09
UniRef50_Q4S505 Cluster: Chromosome 6 SCAF14737, whole genome sh...    64   5e-09
UniRef50_Q5DH68 Cluster: SJCHGC02545 protein; n=2; Schistosoma j...    63   6e-09
UniRef50_Q9NRY6 Cluster: Phospholipid scramblase 3 (PL scramblas...    63   8e-09
UniRef50_Q9VZW1 Cluster: CG1893-PA; n=3; Sophophora|Rep: CG1893-...    62   1e-08
UniRef50_Q4SF70 Cluster: Chromosome undetermined SCAF14608, whol...    60   4e-08
UniRef50_A7RR56 Cluster: Predicted protein; n=5; Nematostella ve...    57   4e-07
UniRef50_A6QPD9 Cluster: Putative uncharacterized protein; n=3; ...    56   9e-07
UniRef50_Q7PSZ6 Cluster: ENSANGP00000020188; n=2; Culicidae|Rep:...    54   3e-06
UniRef50_Q0IEZ5 Cluster: Phospholipid scramblase, putative; n=1;...    54   3e-06
UniRef50_UPI00015A4F52 Cluster: UPI00015A4F52 related cluster; n...    51   3e-05
UniRef50_UPI00015B52CD Cluster: PREDICTED: similar to Plscr1 pro...    49   1e-04
UniRef50_UPI0000E80B84 Cluster: PREDICTED: similar to phospholip...    48   2e-04
UniRef50_A5WVT5 Cluster: Novel protein similar to vertebrate pho...    46   0.001
UniRef50_UPI0000DB785A Cluster: PREDICTED: similar to Phospholip...    44   0.003
UniRef50_A1Z8F5 Cluster: CG9084-PB; n=3; Sophophora|Rep: CG9084-...    44   0.005
UniRef50_Q4RV80 Cluster: Chromosome 15 SCAF14992, whole genome s...    41   0.038
UniRef50_UPI0000E4A125 Cluster: PREDICTED: hypothetical protein;...    39   0.12 
UniRef50_Q3A051 Cluster: Putative uncharacterized protein; n=1; ...    38   0.27 
UniRef50_A6G8H8 Cluster: Putative uncharacterized protein; n=1; ...    36   1.1  
UniRef50_Q6ZR73 Cluster: CDNA FLJ46585 fis, clone THYMU3043779, ...    35   1.9  
UniRef50_Q64D05 Cluster: Putative uncharacterized protein; n=1; ...    34   4.4  
UniRef50_UPI0000F1D9B7 Cluster: PREDICTED: hypothetical protein;...    33   5.8  
UniRef50_Q0FPK4 Cluster: Hydrolase, alpha/beta hydrolase fold fa...    33   5.8  
UniRef50_Q69HQ5 Cluster: Sphingomyelin phosphodiesterase 1; n=1;...    33   5.8  
UniRef50_A1TBL4 Cluster: Putative uncharacterized protein precur...    33   7.7  

>UniRef50_Q2F664 Cluster: Phospholipid scramblase; n=1; Bombyx
           mori|Rep: Phospholipid scramblase - Bombyx mori (Silk
           moth)
          Length = 249

 Score =  305 bits (750), Expect = 5e-82
 Identities = 144/144 (100%), Positives = 144/144 (100%)
 Frame = +3

Query: 57  QIPVVASPPSLLQDLASVDRLFITKRLRVKNVLFLRGKKNRFYVRTPDQKLLYSIEEINS 236
           QIPVVASPPSLLQDLASVDRLFITKRLRVKNVLFLRGKKNRFYVRTPDQKLLYSIEEINS
Sbjct: 29  QIPVVASPPSLLQDLASVDRLFITKRLRVKNVLFLRGKKNRFYVRTPDQKLLYSIEEINS 88

Query: 237 WWVGYLFYGLRPLQLRVNNAQGVEVMRIVRPYACTARVLPCQLQRLQVFSPPGQLVGTVE 416
           WWVGYLFYGLRPLQLRVNNAQGVEVMRIVRPYACTARVLPCQLQRLQVFSPPGQLVGTVE
Sbjct: 89  WWVGYLFYGLRPLQLRVNNAQGVEVMRIVRPYACTARVLPCQLQRLQVFSPPGQLVGTVE 148

Query: 417 QQWTAVKPLYVIRNKERDVVFWIR 488
           QQWTAVKPLYVIRNKERDVVFWIR
Sbjct: 149 QQWTAVKPLYVIRNKERDVVFWIR 172



 Score =  122 bits (295), Expect = 7e-27
 Identities = 55/75 (73%), Positives = 57/75 (76%)
 Frame = +2

Query: 476 VLDTGCFKDIKFDIFRPDGSPVGGTCKRWQGVTHALFLAPVTDRFGVAFERNXXXXXXXX 655
           ++   CFKDIKFDIFRPDGSPVGGTCKRWQGVTHALFLAPVTDRFGVAFERN        
Sbjct: 175 LITISCFKDIKFDIFRPDGSPVGGTCKRWQGVTHALFLAPVTDRFGVAFERNLTLEEKAL 234

Query: 656 XXXXXXXMDYMYYDA 700
                  MDYMYYDA
Sbjct: 235 LLAATWLMDYMYYDA 249


>UniRef50_UPI0000F2E10C Cluster: PREDICTED: similar to phospholipid
           scramblase 4,; n=1; Monodelphis domestica|Rep:
           PREDICTED: similar to phospholipid scramblase 4, -
           Monodelphis domestica
          Length = 469

 Score = 77.0 bits (181), Expect = 5e-13
 Identities = 40/140 (28%), Positives = 74/140 (52%), Gaps = 2/140 (1%)
 Frame = +3

Query: 63  PVVASPPSLLQDLASVDRLFITKRLRVKNVLFLRGKKNRFYVRTPDQKLLYSIEEINSWW 242
           P+   PP L + L+ +D++ + +++ +  ++      NR+ V+    +++Y + E     
Sbjct: 153 PLPNCPPGL-EYLSQLDKVMVHQQVNILEMMTHFETNNRYEVKNSTGQMIYMVIEDTDDV 211

Query: 243 VGYLFYGLRPLQLRVNNAQGVEVMRIVRPYACTARVL--PCQLQRLQVFSPPGQLVGTVE 416
               ++ LRP  LRV +  G E+MR+ RP+ CT       C +Q L+V SPPG  +G + 
Sbjct: 212 TRNAYHSLRPFVLRVTDCMGREIMRMQRPFRCTCCCFCCSCAMQELEVQSPPGVSLGYIR 271

Query: 417 QQWTAVKPLYVIRNKERDVV 476
           Q W   K  + I N++++ V
Sbjct: 272 QHWGCCKANFSIENEKKEHV 291


>UniRef50_A0PG75 Cluster: Phospholipid scramblase family memmber 5;
           n=13; Mammalia|Rep: Phospholipid scramblase family
           memmber 5 - Homo sapiens (Human)
          Length = 271

 Score = 73.3 bits (172), Expect = 6e-12
 Identities = 42/147 (28%), Positives = 79/147 (53%), Gaps = 2/147 (1%)
 Frame = +3

Query: 51  TSQIPVVASPPSLLQDLASVDRLFITKRLRVKNVLFLRGKKNRFYVRTP-DQKLLYSIEE 227
           +S +P V+ PP L + L+ +D + I +++ +  ++      N++ ++    Q++ +++EE
Sbjct: 46  SSFLPTVSLPPGL-EYLSQLDLIIIHQQVELLGMILGAETSNKYEIKNSLGQRIYFAVEE 104

Query: 228 INSWWVGYLFYG-LRPLQLRVNNAQGVEVMRIVRPYACTARVLPCQLQRLQVFSPPGQLV 404
             S      F   LR   LR+ +  G EV+ + RP  C +   PC LQ L++ +PPG +V
Sbjct: 105 --SICFNRTFCSTLRSCTLRITDNSGREVITVNRPLRCNSCWCPCYLQELEIQAPPGTIV 162

Query: 405 GTVEQQWTAVKPLYVIRNKERDVVFWI 485
           G V Q+W    P + I+N  ++ +  I
Sbjct: 163 GYVTQKWDPFLPKFTIQNANKEDILKI 189


>UniRef50_Q9NRQ2 Cluster: Phospholipid scramblase 4 (PL scramblase
           4) (Ca(2+)-dependent phospholipid scramblase 4); n=17;
           Theria|Rep: Phospholipid scramblase 4 (PL scramblase 4)
           (Ca(2+)-dependent phospholipid scramblase 4) - Homo
           sapiens (Human)
          Length = 329

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 38/144 (26%), Positives = 70/144 (48%), Gaps = 2/144 (1%)
 Frame = +3

Query: 63  PVVASPPSLLQDLASVDRLFITKRLRVKNVLFLRGKKNRFYVRTPDQKLLYSIEEINSWW 242
           P+   PP L + L  +D + + +      ++      NR+ ++    +++Y + E    +
Sbjct: 105 PMANCPPGL-EYLVQLDNIHVLQHFEPLEMMTCFETNNRYDIKNNSDQMVYVVTEDTDDF 163

Query: 243 VGYLFYGLRPLQLRVNNAQGVEVMRIVRPYACTARVL--PCQLQRLQVFSPPGQLVGTVE 416
               +  LRP  LRV +  G E+M + RP+ CT      P   Q L+V  PPG  +G V 
Sbjct: 164 TRNAYRTLRPFVLRVTDCMGREIMTMQRPFRCTCCCFCCPSARQELEVQCPPGVTIGFVA 223

Query: 417 QQWTAVKPLYVIRNKERDVVFWIR 488
           + W   + +Y I+N++++ V  +R
Sbjct: 224 EHWNLCRAVYSIQNEKKENVMRVR 247


>UniRef50_Q9NRY7 Cluster: Phospholipid scramblase 2 (PL scramblase
           2) (Ca(2+)-dependent phospholipid scramblase 2); n=30;
           Euteleostomi|Rep: Phospholipid scramblase 2 (PL
           scramblase 2) (Ca(2+)-dependent phospholipid scramblase
           2) - Homo sapiens (Human)
          Length = 224

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 40/141 (28%), Positives = 70/141 (49%)
 Frame = +3

Query: 63  PVVASPPSLLQDLASVDRLFITKRLRVKNVLFLRGKKNRFYVRTPDQKLLYSIEEINSWW 242
           P +  PP L + L+ +D + I +++ +  VLF     N + ++    + +Y   E  ++ 
Sbjct: 6   PPLNCPPGL-EYLSQIDMILIHQQIELLEVLFSFESSNMYEIKNSFGQRIYFAAEDTNFC 64

Query: 243 VGYLFYGLRPLQLRVNNAQGVEVMRIVRPYACTARVLPCQLQRLQVFSPPGQLVGTVEQQ 422
           +       RP  LR+ +  G EV+ + RP  C     PC LQ +++ +PPG  VG V Q 
Sbjct: 65  IRNCCGRSRPFTLRITDNVGREVITLERPLRCNCCCCPCCLQEIEIQAPPGVPVGYVTQT 124

Query: 423 WTAVKPLYVIRNKERDVVFWI 485
           W      + I+N++R+ V  I
Sbjct: 125 WHPCLTKFTIKNQKREDVLKI 145


>UniRef50_O15162 Cluster: Phospholipid scramblase 1 (PL scramblase
           1) (Ca(2+)-dependent phospholipid scramblase 1); n=39;
           Eumetazoa|Rep: Phospholipid scramblase 1 (PL scramblase
           1) (Ca(2+)-dependent phospholipid scramblase 1) - Homo
           sapiens (Human)
          Length = 318

 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 39/141 (27%), Positives = 71/141 (50%)
 Frame = +3

Query: 63  PVVASPPSLLQDLASVDRLFITKRLRVKNVLFLRGKKNRFYVRTPDQKLLYSIEEINSWW 242
           P +  PP L + L+ +D++ I +++ +  VL      N++ ++    + +Y   E     
Sbjct: 91  PPLNCPPGL-EYLSQIDQILIHQQIELLEVLTGFETNNKYEIKNSFGQRVYFAAEDTDCC 149

Query: 243 VGYLFYGLRPLQLRVNNAQGVEVMRIVRPYACTARVLPCQLQRLQVFSPPGQLVGTVEQQ 422
                   RP  LR+ +  G EV+ + RP  C++   PC LQ +++ +PPG  +G V Q 
Sbjct: 150 TRNCCGPSRPFTLRIIDNMGQEVITLERPLRCSSCCCPCCLQEIEIQAPPGVPIGYVIQT 209

Query: 423 WTAVKPLYVIRNKERDVVFWI 485
           W    P + I+N++R+ V  I
Sbjct: 210 WHPCLPKFTIQNEKREDVLKI 230


>UniRef50_Q7T1Q9 Cluster: Phospholipid scramblase 1; n=4;
           Euteleostomi|Rep: Phospholipid scramblase 1 - Oryzias
           latipes (Medaka fish) (Japanese ricefish)
          Length = 196

 Score = 66.9 bits (156), Expect = 5e-10
 Identities = 39/127 (30%), Positives = 63/127 (49%), Gaps = 1/127 (0%)
 Frame = +3

Query: 108 VDRLFITKRLRVKNVLFLRGKKNRFYVRTP-DQKLLYSIEEINSWWVGYLFYGLRPLQLR 284
           VD+L + +++ +   L      N++ +R    Q + Y++EE N          LR   + 
Sbjct: 1   VDQLLMKQKVELVEALVGFESNNKYEIRNVMGQNVFYAVEE-NDCLSRQCCGPLRSFTIH 59

Query: 285 VNNAQGVEVMRIVRPYACTARVLPCQLQRLQVFSPPGQLVGTVEQQWTAVKPLYVIRNKE 464
           V +  G E++ + RP  C +   PC LQ L+V SPPG  VG V QQW    P +++ N+ 
Sbjct: 60  VLDNFGQEIITVTRPLKCMSCFFPCCLQELEVQSPPGNTVGYVIQQWHPFFPKFIVANEH 119

Query: 465 RDVVFWI 485
            + V  I
Sbjct: 120 NEPVLKI 126


>UniRef50_UPI0000D5613B Cluster: PREDICTED: similar to CG9084-PB;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG9084-PB - Tribolium castaneum
          Length = 279

 Score = 65.7 bits (153), Expect = 1e-09
 Identities = 39/138 (28%), Positives = 73/138 (52%), Gaps = 1/138 (0%)
 Frame = +3

Query: 75  SPPSLLQDLASVDRLFITKRLRVKNVLFLRGKKNRFYVRTPDQKLLYSIEEINSWWVGYL 254
           SP   L  L  V ++ I + + + +++     +NR+ V+ P  + +Y   E ++ +    
Sbjct: 56  SPLHGLDFLKDVHQIIIQQTVELTDLMASLESENRYTVKVPRGETIYYATESSTSFQRTC 115

Query: 255 FYGLRPLQLRVNNAQGVEVMRIVRPYAC-TARVLPCQLQRLQVFSPPGQLVGTVEQQWTA 431
           F   R   +R+ +    E ++  R  AC +   +   LQ L+V+ PPG+ VG V+Q++ A
Sbjct: 116 FGSSRAFAMRLYDPTQQEAIQFRRRLACGSCCSIFLYLQELEVWIPPGEYVGKVKQKFNA 175

Query: 432 VKPLYVIRNKERDVVFWI 485
            KP +VI NK+ D+++ I
Sbjct: 176 TKPCFVIYNKQMDIIYRI 193


>UniRef50_Q4S505 Cluster: Chromosome 6 SCAF14737, whole genome
           shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 6
           SCAF14737, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 268

 Score = 63.7 bits (148), Expect = 5e-09
 Identities = 45/154 (29%), Positives = 72/154 (46%), Gaps = 13/154 (8%)
 Frame = +3

Query: 63  PVVASPPSLLQDLASVDRLFITKRLRVKNVLFLRGKKNRFYVR-TPDQKLLYSIEEINSW 239
           P +   P  L+ L  VD+L I +++ +   L      N++ VR T  Q + Y++EE N  
Sbjct: 9   PGIPGCPPGLEYLIQVDQLLIKQKVELIEALIGFESNNKYEVRNTLGQNVFYAVEE-NDC 67

Query: 240 WVGYLFYGLRPLQLRVNNAQGVEVMRIVRPYACTARVLPCQLQ------------RLQVF 383
                   LRP  + + +  G EV+ + RP  C +   PC LQ            +L+V 
Sbjct: 68  LNRQCCGPLRPFSIHILDNFGQEVITVTRPLKCMSCFFPCCLQEHVDANLARPPPQLEVQ 127

Query: 384 SPPGQLVGTVEQQWTAVKPLYVIRNKERDVVFWI 485
           +PPG  VG + QQW    P +++ N+  + V  I
Sbjct: 128 APPGNPVGYIIQQWHPFSPKFIVANEHNEPVLKI 161


>UniRef50_Q5DH68 Cluster: SJCHGC02545 protein; n=2; Schistosoma
           japonicum|Rep: SJCHGC02545 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 230

 Score = 63.3 bits (147), Expect = 6e-09
 Identities = 42/148 (28%), Positives = 70/148 (47%), Gaps = 4/148 (2%)
 Frame = +3

Query: 57  QIPVVASPPSLLQDLASVDRLFITKRLRVKNVLFLRGKKNRFYVRTPDQKLLYSIEEINS 236
           Q P V + P  L+ L  VD+LFI +++ V         +NR+       +++Y   E +S
Sbjct: 2   QRPFVLNYPPGLEHLTQVDQLFIKQKVDVIESFVPFEAQNRYICLNKSGQVVYKCYEESS 61

Query: 237 WWVGYLFYGLRPLQLRVNNAQGVEVMRIVRPYACTAR----VLPCQLQRLQVFSPPGQLV 404
               Y+    R   L + N    EV+R+ RPY C        L C  + L+V SP G  +
Sbjct: 62  LCSRYICGSSRSFVLHIVNDNNAEVIRVTRPYRCDCHPCCSFLDCCQEELEVQSPVGNTI 121

Query: 405 GTVEQQWTAVKPLYVIRNKERDVVFWIR 488
           G V++ +++    Y IR++  + V  +R
Sbjct: 122 GFVKRVFSSCNLDYHIRDRNGNTVLQLR 149


>UniRef50_Q9NRY6 Cluster: Phospholipid scramblase 3 (PL scramblase
           3) (Ca(2+)-dependent phospholipid scramblase 3); n=27;
           Tetrapoda|Rep: Phospholipid scramblase 3 (PL scramblase
           3) (Ca(2+)-dependent phospholipid scramblase 3) - Homo
           sapiens (Human)
          Length = 295

 Score = 62.9 bits (146), Expect = 8e-09
 Identities = 42/134 (31%), Positives = 67/134 (50%), Gaps = 2/134 (1%)
 Frame = +3

Query: 81  PSLLQDLASVDRLFITKRLRVKNVLFLRGKKNRFYVRT-PDQKLLYSIEEINSWWVGYLF 257
           PS L+ L  +D++ I ++             NR+ +R+   Q L  + EE N      L 
Sbjct: 73  PSGLEFLVQIDQILIHQKAERVETFLGWETCNRYELRSGAGQPLGQAAEESNC--CARLC 130

Query: 258 YGLR-PLQLRVNNAQGVEVMRIVRPYACTARVLPCQLQRLQVFSPPGQLVGTVEQQWTAV 434
            G R PL++R+ +    EV+R++RP  C     PC LQ ++V +PPG  +G V Q W   
Sbjct: 131 CGARRPLRVRLADPGDREVLRLLRPLHCGCSCCPCGLQEMEVQAPPGTTIGHVLQTWHPF 190

Query: 435 KPLYVIRNKERDVV 476
            P + I++ +R  V
Sbjct: 191 LPKFSIQDADRQTV 204


>UniRef50_Q9VZW1 Cluster: CG1893-PA; n=3; Sophophora|Rep: CG1893-PA
           - Drosophila melanogaster (Fruit fly)
          Length = 263

 Score = 62.5 bits (145), Expect = 1e-08
 Identities = 40/144 (27%), Positives = 76/144 (52%), Gaps = 2/144 (1%)
 Frame = +3

Query: 60  IPV-VASPPSLLQDLASVDRLFITKRLRVKNVLFLRGKKNRFYVRTPDQKLLYSIEEINS 236
           IPV + + P  L+ L ++D+L +++++    +L     KNRF V+    + +Y   E + 
Sbjct: 44  IPVGMPNCPQGLEYLTALDQLLVSQKIEKLELLTGFETKNRFKVKNSLGQNVYFAYEESD 103

Query: 237 WWVGYLFYGLRPLQLRVNNAQGVEVMRIVRPYACTARV-LPCQLQRLQVFSPPGQLVGTV 413
                +    RP ++++ +    EV+ + RP+ C      P  +  ++V +PPGQ++G+V
Sbjct: 104 CCTRNMLGRSRPFEMKILDNFQNEVLHLYRPFKCDILCCFPSCMNAVEVSAPPGQVIGSV 163

Query: 414 EQQWTAVKPLYVIRNKERDVVFWI 485
           EQ  T ++P + I+N   D V  I
Sbjct: 164 EQVCTFMRPKFNIKNTCGDTVLQI 187



 Score = 34.7 bits (76), Expect = 2.5
 Identities = 18/69 (26%), Positives = 26/69 (37%)
 Frame = +2

Query: 491 CFKDIKFDIFRPDGSPVGGTCKRWQGVTHALFLAPVTDRFGVAFERNXXXXXXXXXXXXX 670
           CF D  F +   +   +G   K+W G+   LF     D F V F  N             
Sbjct: 196 CFSDTNFKVLSANNEEIGKISKQWSGLGRELFTD--ADYFSVTFPLNLDVRMKALIFAAL 253

Query: 671 XXMDYMYYD 697
             +D +YY+
Sbjct: 254 FLIDAVYYE 262


>UniRef50_Q4SF70 Cluster: Chromosome undetermined SCAF14608, whole
           genome shotgun sequence; n=5; Euteleostomi|Rep:
           Chromosome undetermined SCAF14608, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 301

 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 26/101 (25%), Positives = 52/101 (51%)
 Frame = +3

Query: 174 NRFYVRTPDQKLLYSIEEINSWWVGYLFYGLRPLQLRVNNAQGVEVMRIVRPYACTARVL 353
           N++ ++    + +Y  +E N          LR   +++ +    EV+R++RP+ C +   
Sbjct: 109 NQYEIKNSLGQKIYKAKEKNDCCTRNCCGSLRSFDMKIKDNMDREVIRLIRPFRCVSCWC 168

Query: 354 PCQLQRLQVFSPPGQLVGTVEQQWTAVKPLYVIRNKERDVV 476
           PC LQ ++V +PPG  +G ++Q W    P + I+   ++ V
Sbjct: 169 PCCLQEMEVQAPPGTTIGYIKQDWHPFLPRFSIQGANKETV 209



 Score = 35.5 bits (78), Expect = 1.4
 Identities = 18/70 (25%), Positives = 32/70 (45%), Gaps = 1/70 (1%)
 Frame = +2

Query: 491 CFKDIKFDIFRPDG-SPVGGTCKRWQGVTHALFLAPVTDRFGVAFERNXXXXXXXXXXXX 667
           C  D+ F++   D  SP+G   K+W G+   +F    TD FG+ F  +            
Sbjct: 221 CCGDVNFELRGKDSDSPIGRISKQWSGLLKEVFTD--TDNFGIQFPLDMDVKMKAVLLGA 278

Query: 668 XXXMDYMYYD 697
              +D+M+++
Sbjct: 279 CFLIDFMFFE 288


>UniRef50_A7RR56 Cluster: Predicted protein; n=5; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 1617

 Score = 57.2 bits (132), Expect = 4e-07
 Identities = 34/138 (24%), Positives = 63/138 (45%)
 Frame = +3

Query: 72  ASPPSLLQDLASVDRLFITKRLRVKNVLFLRGKKNRFYVRTPDQKLLYSIEEINSWWVGY 251
           A+ P  L+ L  VD+L I +++ +          N++ +     + ++   E        
Sbjct: 81  ANCPPGLEYLTMVDQLLIKQQVELLEAFTGFETNNKYKITNNLGQQVFFAAEDTDCCTRQ 140

Query: 252 LFYGLRPLQLRVNNAQGVEVMRIVRPYACTARVLPCQLQRLQVFSPPGQLVGTVEQQWTA 431
                RP  +++ +    EV+ + RP  C++   PC LQ ++V SPPG +VG   Q W+ 
Sbjct: 141 CCGPSRPFDIKIMDNTQREVIHLTRPLRCSSCWFPCCLQEVEVQSPPGTVVGYCCQSWSI 200

Query: 432 VKPLYVIRNKERDVVFWI 485
             P Y +++  R  +  I
Sbjct: 201 CIPKYTLQDANRQTILQI 218


>UniRef50_A6QPD9 Cluster: Putative uncharacterized protein; n=3;
           Eutheria|Rep: Putative uncharacterized protein - Bos
           taurus (Bovine)
          Length = 247

 Score = 56.0 bits (129), Expect = 9e-07
 Identities = 37/140 (26%), Positives = 73/140 (52%), Gaps = 1/140 (0%)
 Frame = +3

Query: 72  ASPPSLLQDLASVDRLFITKRLRVKNVLFLRGKKNRFY-VRTPDQKLLYSIEEINSWWVG 248
           A+ P  L+ L  ++ LF+ +R  +  V F   + N+ Y V     + LY  EE ++ ++ 
Sbjct: 8   ANCPPGLEYLTQINHLFVCQRFDLLEV-FSPFETNKTYDVMNNQGQRLYFAEEKSNCFIR 66

Query: 249 YLFYGLRPLQLRVNNAQGVEVMRIVRPYACTARVLPCQLQRLQVFSPPGQLVGTVEQQWT 428
           +L    RP  + + +  G +V+ + +    +     C LQ+L+V +PPG+++G V Q + 
Sbjct: 67  HLCGPSRPFTMTIYDNVGCDVITLHKALRWSCCWSNCCLQKLKVEAPPGEIIGYVYQYYH 126

Query: 429 AVKPLYVIRNKERDVVFWIR 488
              P++ I N+ ++ +  IR
Sbjct: 127 PFLPMFKITNENKENLMKIR 146


>UniRef50_Q7PSZ6 Cluster: ENSANGP00000020188; n=2; Culicidae|Rep:
           ENSANGP00000020188 - Anopheles gambiae str. PEST
          Length = 311

 Score = 54.4 bits (125), Expect = 3e-06
 Identities = 38/138 (27%), Positives = 65/138 (47%), Gaps = 1/138 (0%)
 Frame = +3

Query: 75  SPPSLLQDLASVDRLFITKRLRVKNVLFLRGKKNRFYVRTPDQKLLYSIEEINSWWVGYL 254
           SP + L  L  +  +FI +   +  +L      NRF VR P  + LY   E +       
Sbjct: 100 SPRAGLDFLYGLPSVFIQQSYELNELLSGVASDNRFTVRGPSNEALYGASETSD--PKDR 157

Query: 255 FYG-LRPLQLRVNNAQGVEVMRIVRPYACTARVLPCQLQRLQVFSPPGQLVGTVEQQWTA 431
           F+G LRP  L + +    EV+   +   C      C+ Q L+V++ PG+L+G ++Q +  
Sbjct: 158 FWGSLRPFSLSLVDRSHQEVLLFRKNLGCGVFCCFCKNQFLEVWAAPGELIGCIQQDYGV 217

Query: 432 VKPLYVIRNKERDVVFWI 485
           +    V+ N + + +F I
Sbjct: 218 LSQEIVLLNSDINTMFRI 235


>UniRef50_Q0IEZ5 Cluster: Phospholipid scramblase, putative; n=1;
           Aedes aegypti|Rep: Phospholipid scramblase, putative -
           Aedes aegypti (Yellowfever mosquito)
          Length = 204

 Score = 54.4 bits (125), Expect = 3e-06
 Identities = 31/123 (25%), Positives = 56/123 (45%)
 Frame = +3

Query: 90  LQDLASVDRLFITKRLRVKNVLFLRGKKNRFYVRTPDQKLLYSIEEINSWWVGYLFYGLR 269
           +++L   D+L + +R             N + +     + +Y   E  ++W    F   R
Sbjct: 4   IENLKHTDQLLVVRRRESLETEDGPPLTNHYVIENKANETVYWAAEGPAFWARTCFGHNR 63

Query: 270 PLQLRVNNAQGVEVMRIVRPYACTARVLPCQLQRLQVFSPPGQLVGTVEQQWTAVKPLYV 449
           P +L + + Q  + M   RP    +    C+L+R+ +F+P G  VG ++Q W   KP YV
Sbjct: 64  PFELALLDNQRRKTMVFKRPLFYKSWRFLCRLKRMDIFAPEGDHVGRIQQGWFFGKPWYV 123

Query: 450 IRN 458
           + N
Sbjct: 124 VMN 126


>UniRef50_UPI00015A4F52 Cluster: UPI00015A4F52 related cluster; n=1;
           Danio rerio|Rep: UPI00015A4F52 UniRef100 entry - Danio
           rerio
          Length = 199

 Score = 51.2 bits (117), Expect = 3e-05
 Identities = 34/129 (26%), Positives = 58/129 (44%)
 Frame = +3

Query: 99  LASVDRLFITKRLRVKNVLFLRGKKNRFYVRTPDQKLLYSIEEINSWWVGYLFYGLRPLQ 278
           L  +D+ FI K   +   +      N + V+      ++SI E + +    +  G R   
Sbjct: 4   LGRIDQFFIYKERNMDECIDEGLYHNTYTVKDDIGNHVFSILEDSDYCSRNIHTG-RSFT 62

Query: 279 LRVNNAQGVEVMRIVRPYACTARVLPCQLQRLQVFSPPGQLVGTVEQQWTAVKPLYVIRN 458
           + + N    EV+R+  P+ C +    C    ++V SPPG  VG V Q W   +P + + N
Sbjct: 63  MNIVNDSNKEVIRLEHPFICWS----CSGHEVEVQSPPGVPVGHVRQNWHVCQPKFTVEN 118

Query: 459 KERDVVFWI 485
            +R+  F I
Sbjct: 119 NQREPEFKI 127


>UniRef50_UPI00015B52CD Cluster: PREDICTED: similar to Plscr1
           protein; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to Plscr1 protein - Nasonia vitripennis
          Length = 251

 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 21/51 (41%), Positives = 31/51 (60%)
 Frame = +3

Query: 306 EVMRIVRPYACTARVLPCQLQRLQVFSPPGQLVGTVEQQWTAVKPLYVIRN 458
           EV+R+ R   C +   PC LQR+ V +  G+L+G+V Q W   +P Y IR+
Sbjct: 105 EVLRVRRALRCASCCFPCCLQRVTVHTDHGELLGSVTQNWNVWRPSYTIRD 155


>UniRef50_UPI0000E80B84 Cluster: PREDICTED: similar to phospholipid
           scramblase PLSCR isoform 2; n=1; Gallus gallus|Rep:
           PREDICTED: similar to phospholipid scramblase PLSCR
           isoform 2 - Gallus gallus
          Length = 251

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 28/122 (22%), Positives = 57/122 (46%)
 Frame = +3

Query: 63  PVVASPPSLLQDLASVDRLFITKRLRVKNVLFLRGKKNRFYVRTPDQKLLYSIEEINSWW 242
           P+   PP L + L  +D++ I ++L +  +       N++ ++    + +Y   E     
Sbjct: 77  PLPNCPPGL-EYLTQIDQILIHQQLELLEIFIGLESNNKYEIKNSLGQRVYFAAEDTDCC 135

Query: 243 VGYLFYGLRPLQLRVNNAQGVEVMRIVRPYACTARVLPCQLQRLQVFSPPGQLVGTVEQQ 422
                   RP  +++ +  G EV+R+ RP  C++ + PC LQ ++        VG + +Q
Sbjct: 136 TRNCCGPARPFTIKIMDNLGHEVIRLERPLRCSSCLFPCCLQEVKSLDEVSN-VGRISKQ 194

Query: 423 WT 428
           W+
Sbjct: 195 WS 196


>UniRef50_A5WVT5 Cluster: Novel protein similar to vertebrate
           phosopholipid scramblase family; n=1; Danio rerio|Rep:
           Novel protein similar to vertebrate phosopholipid
           scramblase family - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 200

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 25/76 (32%), Positives = 36/76 (47%)
 Frame = +3

Query: 258 YGLRPLQLRVNNAQGVEVMRIVRPYACTARVLPCQLQRLQVFSPPGQLVGTVEQQWTAVK 437
           Y  R   + V +    EV+R+V P  CT     C    L+V SPPG  +G V Q W  + 
Sbjct: 50  YAERFFVMNVTDNLNREVIRLVHPSVCTR----CSSHELEVQSPPGTPIGYVRQNWHILL 105

Query: 438 PLYVIRNKERDVVFWI 485
           P + + N+  +  F I
Sbjct: 106 PKFTVENERGEPEFKI 121


>UniRef50_UPI0000DB785A Cluster: PREDICTED: similar to Phospholipid
           scramblase 3 (PL scramblase 3) (Ca(2+)-dependent
           phospholipid scramblase 3); n=1; Apis mellifera|Rep:
           PREDICTED: similar to Phospholipid scramblase 3 (PL
           scramblase 3) (Ca(2+)-dependent phospholipid scramblase
           3) - Apis mellifera
          Length = 182

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 33/136 (24%), Positives = 63/136 (46%)
 Frame = +3

Query: 81  PSLLQDLASVDRLFITKRLRVKNVLFLRGKKNRFYVRTPDQKLLYSIEEINSWWVGYLFY 260
           P+ L+ L  +D L I K  R   V      KN F+V     + ++++ E + WW      
Sbjct: 13  PTGLEYLIVLDYLGIRKNTR--EVDHFWDVKNEFFVLNIRGETIFNVTEQSDWWGRLCLG 70

Query: 261 GLRPLQLRVNNAQGVEVMRIVRPYACTARVLPCQLQRLQVFSPPGQLVGTVEQQWTAVKP 440
                +  V ++ G +++R+V+P+ C+        Q LQV+S    L+G++ Q    ++P
Sbjct: 71  SSSTCEFHVTDSYGRKLLRMVQPFTCS-------FQTLQVYS-EDVLLGSISQNCYFLRP 122

Query: 441 LYVIRNKERDVVFWIR 488
            + I +     V  ++
Sbjct: 123 TFSINDSTGKTVLRLK 138


>UniRef50_A1Z8F5 Cluster: CG9084-PB; n=3; Sophophora|Rep: CG9084-PB
           - Drosophila melanogaster (Fruit fly)
          Length = 275

 Score = 43.6 bits (98), Expect = 0.005
 Identities = 29/121 (23%), Positives = 60/121 (49%)
 Frame = +3

Query: 99  LASVDRLFITKRLRVKNVLFLRGKKNRFYVRTPDQKLLYSIEEINSWWVGYLFYGLRPLQ 278
           LA +  + I +   + + L     +NR+ VR+P    +++  E ++     L+   RP Q
Sbjct: 71  LADLPSVHIEQTFELNDALTGVSSENRYVVRSPLGDAIFAANESSTEKNRLLWGAGRPFQ 130

Query: 279 LRVNNAQGVEVMRIVRPYACTARVLPCQLQRLQVFSPPGQLVGTVEQQWTAVKPLYVIRN 458
           + + +    E +   +  A  +  + CQ + L+++ PPG L+G V Q  T ++P + I +
Sbjct: 131 MHLLDKTHQEALVFRKKLAMGS--MCCQAKSLEIWIPPGNLLGKVVQSPTFMQPEFFIED 188

Query: 459 K 461
           +
Sbjct: 189 E 189


>UniRef50_Q4RV80 Cluster: Chromosome 15 SCAF14992, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 15
           SCAF14992, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 280

 Score = 40.7 bits (91), Expect = 0.038
 Identities = 21/59 (35%), Positives = 30/59 (50%)
 Frame = +3

Query: 267 RPLQLRVNNAQGVEVMRIVRPYACTARVLPCQLQRLQVFSPPGQLVGTVEQQWTAVKPL 443
           R   L+  + QG +V    RP    A  L C L  + V++P   L+GTV Q+W+   PL
Sbjct: 118 RACSLQGFDCQGRQVFYFERPLRVDACCLGCCLMEMGVYTPQKHLMGTVRQRWSMFTPL 176


>UniRef50_UPI0000E4A125 Cluster: PREDICTED: hypothetical protein;
           n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 229

 Score = 39.1 bits (87), Expect = 0.12
 Identities = 32/109 (29%), Positives = 52/109 (47%), Gaps = 7/109 (6%)
 Frame = +3

Query: 183 YVRTPDQKLLYSIEEINSWWVGYLFYGLRPLQLRVNNA--QGVEVMRIVRPYACTARV-- 350
           Y+   DQ L++  +++  + VG    G+R   + VN +  Q  EVMR+ R + C A    
Sbjct: 42  YLTNVDQILVH--QQVEFFEVGRRVTGIRLKIVLVNKSTSQWKEVMRVTREFKCCAGCCW 99

Query: 351 ---LPCQLQRLQVFSPPGQLVGTVEQQWTAVKPLYVIRNKERDVVFWIR 488
              + C    + V +P GQ++G V Q  +   P Y I +  R  V  +R
Sbjct: 100 CANIDCCGMEITVEAPVGQVMGYVRQAQSGWYPNYNILDASRSCVLKVR 148


>UniRef50_Q3A051 Cluster: Putative uncharacterized protein; n=1;
           Pelobacter carbinolicus DSM 2380|Rep: Putative
           uncharacterized protein - Pelobacter carbinolicus
           (strain DSM 2380 / Gra Bd 1)
          Length = 197

 Score = 37.9 bits (84), Expect = 0.27
 Identities = 27/130 (20%), Positives = 61/130 (46%), Gaps = 2/130 (1%)
 Frame = +3

Query: 90  LQDLASVDRLFITKRLRVKNVLFLRGKKNRFYVR-TPDQKLLYSIEEINSWWVGYLFYGL 266
           ++ L S + L ++++     +L     +NR+ +  T  Q LL + EE  +  + +    L
Sbjct: 1   MERLTSAEGLVVSQKKEWGEILTGFETRNRYRIMDTQGQDLLLAAEEGGNLLLRWFLKAL 60

Query: 267 RPLQLRVNNAQGVEVMRIVRPYACTARVLPCQLQRLQVFSPPGQLVGTVEQQWTAVKPLY 446
           RP  ++V       ++R+ RP+              Q+    G+ +GT+ +Q+  ++ +Y
Sbjct: 61  RPFTVQVRGMDNNSMLRVRRPFRFF-------FHEAQISDAAGKPLGTIRRQFALLRRIY 113

Query: 447 VIRNKE-RDV 473
            + + + RD+
Sbjct: 114 TVTDAQGRDL 123


>UniRef50_A6G8H8 Cluster: Putative uncharacterized protein; n=1;
           Plesiocystis pacifica SIR-1|Rep: Putative
           uncharacterized protein - Plesiocystis pacifica SIR-1
          Length = 204

 Score = 35.9 bits (79), Expect = 1.1
 Identities = 26/119 (21%), Positives = 53/119 (44%), Gaps = 5/119 (4%)
 Frame = +3

Query: 111 DRLFITKRLRVKNVLFLRGKKNRFYVRTPDQ-KLLYSIEEINSWWVGYLFYGL----RPL 275
           D L + ++  +  +      +N + + +P    +LY+ E      +G+L        RP 
Sbjct: 10  DSLVVRQKKELTEMFTDLESRNNYAIESPTGGTMLYAAESGKDGVMGFLVRSALKSSRPF 69

Query: 276 QLRVNNAQGVEVMRIVRPYACTARVLPCQLQRLQVFSPPGQLVGTVEQQWTAVKPLYVI 452
           ++ + +A+G  V+ + RP+          L RL VF   G   G ++Q+W+ +   + I
Sbjct: 70  KISIRDARGASVLELDRPWRWF-------LARLDVFDGKGVAQGAIQQRWSLLAKRFSI 121


>UniRef50_Q6ZR73 Cluster: CDNA FLJ46585 fis, clone THYMU3043779,
           highly similar to Phospholipid scramblase 4; n=3;
           Eutheria|Rep: CDNA FLJ46585 fis, clone THYMU3043779,
           highly similar to Phospholipid scramblase 4 - Homo
           sapiens (Human)
          Length = 224

 Score = 35.1 bits (77), Expect = 1.9
 Identities = 14/42 (33%), Positives = 26/42 (61%)
 Frame = +3

Query: 363 LQRLQVFSPPGQLVGTVEQQWTAVKPLYVIRNKERDVVFWIR 488
           L +L+V  PPG  +G V + W   + +Y I+N++++ V  +R
Sbjct: 101 LVQLEVQCPPGVTIGFVAEHWNLCRAVYSIQNEKKENVMRVR 142


>UniRef50_Q64D05 Cluster: Putative uncharacterized protein; n=1;
           uncultured archaeon GZfos19C7|Rep: Putative
           uncharacterized protein - uncultured archaeon GZfos19C7
          Length = 154

 Score = 33.9 bits (74), Expect = 4.4
 Identities = 18/65 (27%), Positives = 36/65 (55%), Gaps = 5/65 (7%)
 Frame = +3

Query: 99  LASVDRLFITKRLRVKNVLFLRGKKNRF---YVRT--PDQKLLYSIEEINSWWVGYLFYG 263
           +  + R+ ++K+L   N +F RG  NR    Y+ +  PD++  ++  +  S W+  L+  
Sbjct: 78  VTKLSRMALSKKLSGTNWMFFRGVYNRLLTCYINSLEPDERFFFARLKTASLWMEALYGS 137

Query: 264 LRPLQ 278
           +RPL+
Sbjct: 138 IRPLK 142


>UniRef50_UPI0000F1D9B7 Cluster: PREDICTED: hypothetical protein;
           n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
           Danio rerio
          Length = 273

 Score = 33.5 bits (73), Expect = 5.8
 Identities = 31/125 (24%), Positives = 50/125 (40%)
 Frame = +3

Query: 90  LQDLASVDRLFITKRLRVKNVLFLRGKKNRFYVRTPDQKLLYSIEEINSWWVGYLFYGLR 269
           L  L +V RL IT R  ++    +  +         DQ L  ++EE +S          R
Sbjct: 67  LTALRTVTRLHITARPELQGPQCVARRTYSICSENRDQ-LFVAVEE-SSCMCMQCCGPAR 124

Query: 270 PLQLRVNNAQGVEVMRIVRPYACTARVLPCQLQRLQVFSPPGQLVGTVEQQWTAVKPLYV 449
              LR  +     V    RP       L C L  ++ ++   +L+GTV Q+W+   P   
Sbjct: 125 SCSLRGFDKDSECVFLFERPLRADMCCLGCCLMEIRAYTAERELIGTVHQRWSMFTPYLE 184

Query: 450 IRNKE 464
           + + E
Sbjct: 185 VCDSE 189


>UniRef50_Q0FPK4 Cluster: Hydrolase, alpha/beta hydrolase fold
           family protein; n=2; Rhodobacteraceae|Rep: Hydrolase,
           alpha/beta hydrolase fold family protein - Roseovarius
           sp. HTCC2601
          Length = 662

 Score = 33.5 bits (73), Expect = 5.8
 Identities = 16/44 (36%), Positives = 23/44 (52%)
 Frame = +2

Query: 404 RHSRTAMDCGQTSVRDPE*GTRCGVLDTGCFKDIKFDIFRPDGS 535
           R S+ A D     + DPE     G LDT C +D++  +  PDG+
Sbjct: 618 RFSQCAKDITAAFIEDPE-----GALDTSCVEDLRLPVMLPDGT 656


>UniRef50_Q69HQ5 Cluster: Sphingomyelin phosphodiesterase 1; n=1;
           Ciona intestinalis|Rep: Sphingomyelin phosphodiesterase
           1 - Ciona intestinalis (Transparent sea squirt)
          Length = 599

 Score = 33.5 bits (73), Expect = 5.8
 Identities = 15/53 (28%), Positives = 24/53 (45%), Gaps = 1/53 (1%)
 Frame = -3

Query: 514 VELNVLEAARIQNTTSRSLFRITYRGLTAVHCCSTV-PTSCPGGEKTWSRCSW 359
           +E N +    I    + +LF +    LT    C  + PTSCP  + +W+   W
Sbjct: 118 IETNSVCEGMIHELQNETLFLLNKLQLTGSQLCGLIFPTSCPANDLSWNNNKW 170


>UniRef50_A1TBL4 Cluster: Putative uncharacterized protein
           precursor; n=1; Mycobacterium vanbaalenii PYR-1|Rep:
           Putative uncharacterized protein precursor -
           Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1)
          Length = 335

 Score = 33.1 bits (72), Expect = 7.7
 Identities = 21/51 (41%), Positives = 28/51 (54%)
 Frame = -1

Query: 624 SKATPNLSVTGARNNACVTPCQRLQVPPTGEPSGLKMSNLMSLKQPVSKTP 472
           S A    +VTGA   A  TP +R  VPPTG+P   K+ NL +  +P+   P
Sbjct: 8   SAAMAVAAVTGAAVMA--TPMER-PVPPTGDPGSSKLVNLAASSRPLYPWP 55


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 759,115,587
Number of Sequences: 1657284
Number of extensions: 15265397
Number of successful extensions: 40637
Number of sequences better than 10.0: 33
Number of HSP's better than 10.0 without gapping: 38970
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 40626
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 62969581935
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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