Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Nnor0473
(680 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P08249 Cluster: Malate dehydrogenase, mitochondrial pre... 239 4e-62
UniRef50_P40926 Cluster: Malate dehydrogenase, mitochondrial pre... 237 2e-61
UniRef50_Q42972 Cluster: Malate dehydrogenase, glyoxysomal precu... 215 8e-55
UniRef50_A2QMH9 Cluster: Malate dehydrogenase; n=7; Fungi/Metazo... 211 1e-53
UniRef50_Q9SN86 Cluster: Malate dehydrogenase, chloroplast precu... 208 7e-53
UniRef50_Q6BM17 Cluster: Malate dehydrogenase; n=4; Eukaryota|Re... 188 1e-46
UniRef50_A7SQS1 Cluster: Predicted protein; n=1; Nematostella ve... 186 3e-46
UniRef50_Q9Y7R8 Cluster: Malate dehydrogenase; n=13; Dikarya|Rep... 185 8e-46
UniRef50_Q9VU29 Cluster: Malate dehydrogenase; n=5; Protostomia|... 184 2e-45
UniRef50_Q6FL22 Cluster: Malate dehydrogenase; n=1; Candida glab... 167 2e-40
UniRef50_Q4Q3J3 Cluster: Malate dehydrogenase, putative; n=3; Le... 167 3e-40
UniRef50_P32419 Cluster: Malate dehydrogenase, peroxisomal; n=24... 158 1e-37
UniRef50_Q9VU28 Cluster: Malate dehydrogenase; n=3; Sophophora|R... 156 4e-37
UniRef50_A7TL95 Cluster: Putative uncharacterized protein; n=1; ... 156 4e-37
UniRef50_Q4QDF0 Cluster: Glycosomal malate dehydrogenase; n=9; T... 149 5e-35
UniRef50_Q5ENS5 Cluster: Malate dehydrogenase; n=1; Heterocapsa ... 132 6e-30
UniRef50_P22133 Cluster: Malate dehydrogenase, cytoplasmic; n=3;... 132 8e-30
UniRef50_A3BMG8 Cluster: Putative uncharacterized protein; n=3; ... 130 3e-29
UniRef50_UPI0000D571DB Cluster: PREDICTED: similar to CG7998-PA;... 126 4e-28
UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep: A... 126 4e-28
UniRef50_UPI00005A0834 Cluster: PREDICTED: similar to Malate deh... 125 1e-27
UniRef50_A7TSF5 Cluster: Putative uncharacterized protein; n=1; ... 122 1e-26
UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces cere... 120 4e-26
UniRef50_Q86DP2 Cluster: Malate dehydrogenase; n=11; Fungi/Metaz... 118 1e-25
UniRef50_UPI0000DB76D8 Cluster: PREDICTED: similar to CG7998-PA;... 111 2e-23
UniRef50_UPI0000D55CD8 Cluster: PREDICTED: similar to Malate DeH... 107 2e-22
UniRef50_Q017A6 Cluster: Malate dehydrogenase; n=2; cellular org... 106 4e-22
UniRef50_UPI0000D56DC5 Cluster: PREDICTED: similar to Malate deh... 96 6e-19
UniRef50_Q4Q3J5 Cluster: Malate dehydrogenase, putative; n=5; Tr... 96 8e-19
UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2... 84 3e-15
UniRef50_Q8ZVB2 Cluster: Malate dehydrogenase; n=14; Thermoprote... 84 3e-15
UniRef50_P16115 Cluster: L-lactate dehydrogenase; n=4; Thermotog... 82 1e-14
UniRef50_UPI00015B4591 Cluster: PREDICTED: similar to mitochondr... 81 2e-14
UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3; Acti... 81 2e-14
UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|R... 80 6e-14
UniRef50_A6Q7S2 Cluster: Malate dehydrogenase, NAD-dependent; n=... 79 1e-13
UniRef50_Q3J7E7 Cluster: Malate dehydrogenase; n=5; Gammaproteob... 78 2e-13
UniRef50_UPI00015B5ACF Cluster: PREDICTED: similar to ENSANGP000... 77 3e-13
UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular o... 77 4e-13
UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|R... 77 5e-13
UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;... 76 7e-13
UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Re... 76 9e-13
UniRef50_Q64P62 Cluster: Malate dehydrogenase; n=28; Bacteroidet... 76 9e-13
UniRef50_A0RXX8 Cluster: Malate/L-lactate dehydrogenase; n=1; Ce... 75 1e-12
UniRef50_A2SNY0 Cluster: Malate/lactate dehydrogenases-like prot... 75 2e-12
UniRef50_A7DRG3 Cluster: Lactate/malate dehydrogenase; n=1; Cand... 74 4e-12
UniRef50_O08349 Cluster: Malate dehydrogenase; n=1; Archaeoglobu... 73 5e-12
UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD bindi... 73 6e-12
UniRef50_Q979N9 Cluster: Malate dehydrogenase; n=4; Thermoplasma... 73 6e-12
UniRef50_Q8TWG5 Cluster: Malate dehydrogenase; n=2; Euryarchaeot... 73 6e-12
UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=... 73 9e-12
UniRef50_Q7M9A7 Cluster: Malate dehydrogenase; n=4; Epsilonprote... 73 9e-12
UniRef50_A7I2F1 Cluster: Malate dehydrogenase; n=1; Campylobacte... 71 3e-11
UniRef50_Q81K80 Cluster: L-lactate dehydrogenase 2; n=12; Firmic... 71 3e-11
UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter... 70 6e-11
UniRef50_Q3ZZJ7 Cluster: Malate dehydrogenase; n=5; cellular org... 69 8e-11
UniRef50_Q7UY63 Cluster: L-lactate/malate dehydrogenase; n=2; Pl... 69 1e-10
UniRef50_Q1FID3 Cluster: L-lactate dehydrogenase precursor; n=1;... 69 1e-10
UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1; ... 69 1e-10
UniRef50_Q892U0 Cluster: L-lactate dehydrogenase; n=12; Bacteria... 69 1e-10
UniRef50_Q7NHJ3 Cluster: Malate dehydrogenase; n=13; cellular or... 68 2e-10
UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex ae... 68 2e-10
UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2; ... 68 2e-10
UniRef50_A5KJY5 Cluster: Putative uncharacterized protein; n=2; ... 67 3e-10
UniRef50_A3EWH3 Cluster: Malate/lactate dehydrogenase; n=1; Lept... 67 3e-10
UniRef50_A4L2P0 Cluster: L-lactate dehydrogenase; n=4; Lactobaci... 66 6e-10
UniRef50_Q18WQ6 Cluster: Malate dehydrogenase, NAD-dependent; n=... 66 7e-10
UniRef50_P19869 Cluster: L-lactate dehydrogenase 2; n=17; Bacter... 66 7e-10
UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3; Methanomi... 66 1e-09
UniRef50_Q6A9C3 Cluster: L-lactate dehydrogenase; n=2; Propionib... 66 1e-09
UniRef50_Q2S4R2 Cluster: L-lactate dehydrogenase; n=1; Salinibac... 65 1e-09
UniRef50_Q27743 Cluster: L-lactate dehydrogenase; n=17; Apicompl... 65 2e-09
UniRef50_Q8XP62 Cluster: L-lactate dehydrogenase; n=11; Clostrid... 65 2e-09
UniRef50_P59390 Cluster: L-lactate dehydrogenase 2; n=8; Lactoba... 64 2e-09
UniRef50_A4BB89 Cluster: Lactate dehydrogenase; n=2; Gammaproteo... 64 3e-09
UniRef50_A0RPE9 Cluster: Malate dehydrogenase; n=1; Campylobacte... 64 3e-09
UniRef50_P11386 Cluster: Malate dehydrogenase; n=6; Sulfolobacea... 64 3e-09
UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasm... 64 3e-09
UniRef50_O26290 Cluster: Malate dehydrogenase; n=2; Methanobacte... 64 4e-09
UniRef50_P62056 Cluster: L-lactate dehydrogenase; n=2; Bacteria|... 63 5e-09
UniRef50_Q81XJ7 Cluster: L-lactate dehydrogenase 3; n=13; Firmic... 62 2e-08
UniRef50_Q6JH30 Cluster: Lactate dehydrogenase; n=3; Plasmodium ... 61 2e-08
UniRef50_Q6F0L9 Cluster: L-lactate dehydrogenase; n=6; Mollicute... 61 2e-08
UniRef50_P0A3M9 Cluster: L-lactate dehydrogenase; n=140; Bacteri... 61 3e-08
UniRef50_Q98PG4 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm... 61 3e-08
UniRef50_P62051 Cluster: L-lactate dehydrogenase; n=2; Desulfovi... 61 3e-08
UniRef50_Q8I8U4 Cluster: Lactate dehydrogenase; n=3; Eimeriorina... 60 4e-08
UniRef50_A3DCA4 Cluster: L-lactate dehydrogenase precursor; n=2;... 60 5e-08
UniRef50_Q838C9 Cluster: L-lactate dehydrogenase 2; n=9; Bacilli... 60 6e-08
UniRef50_Q8ELF0 Cluster: L-lactate dehydrogenase; n=5; Bacillace... 59 9e-08
UniRef50_Q6KIP9 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm... 59 9e-08
UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;... 58 1e-07
UniRef50_A6M0Q2 Cluster: L-lactate dehydrogenase; n=1; Clostridi... 58 2e-07
UniRef50_Q9P4B6 Cluster: L-lactate dehydrogenase A; n=48; Rhizop... 58 2e-07
UniRef50_A3JXA9 Cluster: L-lactate dehydrogenase; n=1; Sagittula... 58 3e-07
UniRef50_P50933 Cluster: L-lactate dehydrogenase; n=7; Bacteria|... 57 3e-07
UniRef50_Q1IRL5 Cluster: L-lactate dehydrogenase; n=6; Bacteria|... 57 5e-07
UniRef50_O51114 Cluster: L-lactate dehydrogenase; n=4; Borrelia ... 57 5e-07
UniRef50_UPI0000DB6C4F Cluster: PREDICTED: similar to Malate DeH... 56 6e-07
UniRef50_Q03BE6 Cluster: L-lactate dehydrogenase; n=1; Lactobaci... 56 8e-07
UniRef50_A4A2L6 Cluster: L-lactate dehydrogenase; n=4; Bacteria|... 56 8e-07
UniRef50_Q9EVR0 Cluster: L-lactate dehydrogenase; n=1; Selenomon... 56 8e-07
UniRef50_Q87JV1 Cluster: Lactate dehydrogenase; n=4; Vibrio|Rep:... 55 1e-06
UniRef50_A1HSK3 Cluster: Lactate/malate dehydrogenase; n=1; Ther... 55 1e-06
UniRef50_P07864 Cluster: L-lactate dehydrogenase C chain; n=371;... 55 1e-06
UniRef50_Q64YY6 Cluster: Malate dehydrogenase; n=5; Bacteroidale... 54 3e-06
UniRef50_A2UB98 Cluster: Lactate/malate dehydrogenase precursor;... 53 7e-06
UniRef50_Q07841 Cluster: Malate dehydrogenase; n=7; Halobacteria... 53 7e-06
UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4; Bacteroidale... 52 1e-05
UniRef50_A3CTN0 Cluster: Lactate/malate dehydrogenase; n=1; Meth... 52 2e-05
UniRef50_A1U9V0 Cluster: Lactate/malate dehydrogenase; n=6; Acti... 51 2e-05
UniRef50_Q4JY42 Cluster: L-lactate dehydrogenase; n=1; Corynebac... 51 2e-05
UniRef50_P20619 Cluster: L-lactate dehydrogenase X; n=14; Bacill... 51 2e-05
UniRef50_Q4UJ29 Cluster: L-lactate dehydrogenase, putative; n=2;... 51 3e-05
UniRef50_UPI000038D9FF Cluster: COG0039: Malate/lactate dehydrog... 50 4e-05
UniRef50_UPI0000DB7268 Cluster: PREDICTED: similar to L-lactate ... 50 5e-05
UniRef50_Q97DC6 Cluster: L-lactate dehydrogenase 2; n=1; Clostri... 50 5e-05
UniRef50_Q23CW4 Cluster: Malate dehydrogenase, cytoplasmic, puta... 49 1e-04
UniRef50_P61973 Cluster: Malate dehydrogenase; n=43; Bacteria|Re... 48 2e-04
UniRef50_Q0UX88 Cluster: L-lactate dehydrogenase; n=2; Phaeospha... 48 3e-04
UniRef50_Q9PHY2 Cluster: Probable malate dehydrogenase; n=12; Ca... 47 4e-04
UniRef50_P47698 Cluster: L-lactate dehydrogenase; n=2; Mycoplasm... 47 4e-04
UniRef50_Q4L941 Cluster: L-lactate dehydrogenase; n=1; Staphyloc... 47 5e-04
UniRef50_Q5M0L6 Cluster: L-2-hydroxyisocaproate dehydrogenase; n... 46 6e-04
UniRef50_O52354 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm... 46 6e-04
UniRef50_Q7QQW5 Cluster: Malate dehydrogenase; n=2; Giardia inte... 46 0.001
UniRef50_Q5B0T8 Cluster: Putative uncharacterized protein; n=1; ... 45 0.001
UniRef50_P59050 Cluster: L-lactate dehydrogenase 1; n=3; Bifidob... 45 0.001
UniRef50_Q014D4 Cluster: Chromosome 08 contig 1, DNA sequence; n... 45 0.002
UniRef50_Q0PQR8 Cluster: Malate dehydrogenase NAD-dependent; n=1... 44 0.003
UniRef50_Q017A7 Cluster: Chromosome 06 contig 1, DNA sequence; n... 44 0.003
UniRef50_A2E124 Cluster: Malate dehydrogenase; n=6; Trichomonadi... 44 0.003
UniRef50_A0D8T3 Cluster: Malate dehydrogenase; n=2; Paramecium t... 44 0.003
UniRef50_Q9GPV2 Cluster: Cytosolic malate dehydrogenase; n=4; Tr... 44 0.005
UniRef50_Q5FIY9 Cluster: L-LDH; n=6; Lactobacillus|Rep: L-LDH - ... 43 0.006
UniRef50_O34358 Cluster: Probable serine protease do-like htrA; ... 43 0.006
UniRef50_UPI00015974E8 Cluster: HtrA; n=1; Bacillus amyloliquefa... 43 0.008
UniRef50_UPI0000DB7267 Cluster: PREDICTED: similar to Ecdysone-i... 43 0.008
UniRef50_A2QJT7 Cluster: Catalytic activity: precursor; n=1; Asp... 43 0.008
UniRef50_A2SR33 Cluster: Lactate/malate dehydrogenase; n=1; Meth... 42 0.014
UniRef50_A1W9K7 Cluster: Malate dehydrogenase; n=95; cellular or... 42 0.018
UniRef50_Q6A6E3 Cluster: L-lactate dehydrogenase; n=1; Propionib... 41 0.024
UniRef50_P14295 Cluster: L-2-hydroxyisocaproate dehydrogenase; n... 40 0.056
UniRef50_Q03ZZ4 Cluster: Enzyme with possible activities of L-2-... 39 0.098
UniRef50_A7DSJ4 Cluster: Lactate/malate dehydrogenase; n=1; Cand... 39 0.098
UniRef50_Q9CGG8 Cluster: L-lactate dehydrogenase 3; n=3; Lactoco... 38 0.30
UniRef50_Q4DTK0 Cluster: Putative uncharacterized protein; n=1; ... 37 0.52
UniRef50_Q9Z6N1 Cluster: Malate dehydrogenase; n=8; Chlamydiacea... 36 0.69
UniRef50_Q46780 Cluster: BfpF; n=4; Enterobacteriaceae|Rep: BfpF... 36 0.91
UniRef50_UPI0001554DCB Cluster: PREDICTED: similar to Zinc finge... 36 1.2
UniRef50_A6W5C7 Cluster: D-alanyl-D-alanine carboxypeptidase/D-a... 36 1.2
UniRef50_Q8IE66 Cluster: Oxidoreductase, putative; n=6; Plasmodi... 36 1.2
UniRef50_A5IYS9 Cluster: L-lactate dehydrogenase; n=2; Mycoplasm... 35 1.6
UniRef50_Q91PS6 Cluster: ORF4; n=2; Torque teno virus|Rep: ORF4 ... 35 2.1
UniRef50_Q8NQ95 Cluster: Predicted nucleoside-diphosphate-sugar ... 35 2.1
UniRef50_UPI000049A32B Cluster: protein kinase; n=1; Entamoeba h... 34 2.8
UniRef50_UPI0000D8BD94 Cluster: UPI0000D8BD94 related cluster; n... 34 2.8
UniRef50_Q0JLJ7 Cluster: Os01g0595100 protein; n=6; Oryza sativa... 34 2.8
UniRef50_O61865 Cluster: Putative uncharacterized protein; n=9; ... 34 2.8
UniRef50_UPI0000DD82B5 Cluster: PREDICTED: hypothetical protein;... 34 3.7
UniRef50_Q81Y95 Cluster: Serine protease; n=16; Bacillaceae|Rep:... 34 3.7
UniRef50_Q608X6 Cluster: Hydrophobe/amphiphile Efflux-1 (HAE1) f... 34 3.7
UniRef50_A6ESK5 Cluster: LysM-repeat protein; n=1; unidentified ... 34 3.7
UniRef50_A6CMQ6 Cluster: HtrA; n=1; Bacillus sp. SG-1|Rep: HtrA ... 34 3.7
UniRef50_Q9VY98 Cluster: CG9941-PA; n=5; Drosophila|Rep: CG9941-... 34 3.7
UniRef50_Q4S3J0 Cluster: Chromosome 1 SCAF14749, whole genome sh... 33 4.9
UniRef50_Q3MGZ6 Cluster: Putative uncharacterized protein precur... 33 4.9
UniRef50_A3VG30 Cluster: Putative uncharacterized protein; n=1; ... 33 4.9
UniRef50_A0VEV1 Cluster: Putative uncharacterized protein; n=1; ... 33 4.9
UniRef50_A2XSM8 Cluster: Putative uncharacterized protein; n=2; ... 33 4.9
UniRef50_Q2UFR5 Cluster: Predicted protein; n=2; Aspergillus|Rep... 33 4.9
UniRef50_A2R1L8 Cluster: Contig An13c0060, complete genome; n=2;... 33 4.9
UniRef50_Q4T0R0 Cluster: Chromosome undetermined SCAF10884, whol... 33 6.4
UniRef50_Q0SBH8 Cluster: Pyruvate dehydrogenase E1 component; n=... 33 6.4
UniRef50_UPI0000D9F76A Cluster: PREDICTED: hypothetical protein,... 33 8.5
UniRef50_Q91LF0 Cluster: ORF90; n=1; Shrimp white spot syndrome ... 33 8.5
UniRef50_Q9XVM1 Cluster: Putative uncharacterized protein tag-65... 33 8.5
UniRef50_A7SI71 Cluster: Predicted protein; n=1; Nematostella ve... 33 8.5
UniRef50_Q8NHM5 Cluster: JmjC domain-containing histone demethyl... 33 8.5
>UniRef50_P08249 Cluster: Malate dehydrogenase, mitochondrial
precursor; n=514; cellular organisms|Rep: Malate
dehydrogenase, mitochondrial precursor - Mus musculus
(Mouse)
Length = 338
Score = 239 bits (585), Expect = 4e-62
Identities = 119/199 (59%), Positives = 147/199 (73%)
Frame = +3
Query: 72 MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYD 251
M S +PA A++ ++FST++Q N K IGQPL+LLLK +PLV+RL LYD
Sbjct: 1 MLSALARPAGAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYD 57
Query: 252 IAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNT 431
IA TPGVAADLSH+ T A V G+ GPE+L +K DVVVIPAGVPRKPGMTRDDLFNT
Sbjct: 58 IAH-TPGVAADLSHIETRANVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNT 116
Query: 432 NASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVR 611
NA+IV + + AQ+ P+A+V II NPVNST+PI +EV KK GVY+PN++ GVTTLD+VR
Sbjct: 117 NATIVATLTAACAQHCPEAMVCIIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVR 176
Query: 612 AATFVGEINGVDPTSVAVP 668
A TFV E+ G+DP V VP
Sbjct: 177 ANTFVAELKGLDPARVNVP 195
>UniRef50_P40926 Cluster: Malate dehydrogenase, mitochondrial
precursor; n=119; cellular organisms|Rep: Malate
dehydrogenase, mitochondrial precursor - Homo sapiens
(Human)
Length = 338
Score = 237 bits (580), Expect = 2e-61
Identities = 116/199 (58%), Positives = 147/199 (73%)
Frame = +3
Query: 72 MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYD 251
M S +P + A++ ++FST++Q N K IGQPL+LLLK +PLV+RL LYD
Sbjct: 1 MLSALARPVSAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYD 57
Query: 252 IAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNT 431
IA TPGVAADLSH+ T A V G+ GPE+L +K DVVVIPAGVPRKPGMTRDDLFNT
Sbjct: 58 IAH-TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNT 116
Query: 432 NASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVR 611
NA+IV + + AQ+ P+A++ +I NPVNST+PI +EV KK GVY+PN++ GVTTLD+VR
Sbjct: 117 NATIVATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVR 176
Query: 612 AATFVGEINGVDPTSVAVP 668
A TFV E+ G+DP V VP
Sbjct: 177 ANTFVAELKGLDPARVNVP 195
>UniRef50_Q42972 Cluster: Malate dehydrogenase, glyoxysomal
precursor; n=11; Eukaryota|Rep: Malate dehydrogenase,
glyoxysomal precursor - Oryza sativa subsp. japonica
(Rice)
Length = 356
Score = 215 bits (525), Expect = 8e-55
Identities = 109/172 (63%), Positives = 125/172 (72%)
Frame = +3
Query: 153 FKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGP 332
FK IGQPLALL+K NPLV+ L LYD+ TPGV AD+SHMNT A V G G
Sbjct: 45 FKVAILGASGGIGQPLALLMKMNPLVSVLHLYDVVN-TPGVTADISHMNTGAVVRGFLGQ 103
Query: 333 EELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNP 512
+L A+ D+V+IPAGVPRKPGMTRDDLFN NA IVR + IA+ P AIV +I+NP
Sbjct: 104 PQLENALTGMDLVIIPAGVPRKPGMTRDDLFNINAGIVRTLCEGIAKCCPNAIVNVISNP 163
Query: 513 VNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVRAATFVGEINGVDPTSVAVP 668
VNSTVPIA+EV KKAG YDP R+LGVTTLDVVRA TFV E+ G+DP V VP
Sbjct: 164 VNSTVPIAAEVFKKAGTYDPKRLLGVTTLDVVRANTFVAEVLGLDPRDVNVP 215
>UniRef50_A2QMH9 Cluster: Malate dehydrogenase; n=7; Fungi/Metazoa
group|Rep: Malate dehydrogenase - Aspergillus niger
Length = 340
Score = 211 bits (516), Expect = 1e-53
Identities = 104/182 (57%), Positives = 137/182 (75%), Gaps = 1/182 (0%)
Frame = +3
Query: 123 KNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNT 302
++FS ++ + K IGQPL+LL+KQNPLVT LALYDI PGVAAD+SH+NT
Sbjct: 14 RSFSASASQASKVAVLGAAGGIGQPLSLLMKQNPLVTDLALYDIRG-GPGVAADISHINT 72
Query: 303 PAKVSGHKG-PEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 479
+ V G++ P L A+K +++++IPAGVPRKPGMTRDDLFNTNASIVRD+A + A+ A
Sbjct: 73 NSTVKGYEPTPSGLRDALKGSEIILIPAGVPRKPGMTRDDLFNTNASIVRDLAKAAAEAA 132
Query: 480 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVRAATFVGEINGVDPTSV 659
P+A + +I+NPVNSTVPI SEV K GVY+P R+ GVTTLDVVRA+ F+ ++ G +P +
Sbjct: 133 PEANILVISNPVNSTVPIVSEVYKSKGVYNPKRLFGVTTLDVVRASRFISQVKGTNPANE 192
Query: 660 AV 665
AV
Sbjct: 193 AV 194
>UniRef50_Q9SN86 Cluster: Malate dehydrogenase, chloroplast
precursor; n=41; cellular organisms|Rep: Malate
dehydrogenase, chloroplast precursor - Arabidopsis
thaliana (Mouse-ear cress)
Length = 403
Score = 208 bits (509), Expect = 7e-53
Identities = 103/161 (63%), Positives = 125/161 (77%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDAD 365
IGQPL+LL+K +PLV+ L LYDIA V GVAADLSH NTP++V GP EL+ +KD +
Sbjct: 94 IGQPLSLLIKMSPLVSTLHLYDIANVK-GVAADLSHCNTPSQVRDFTGPSELADCLKDVN 152
Query: 366 VVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEV 545
VVVIPAGVPRKPGMTRDDLFN NA+IV+ + ++A+N P A + II+NPVNSTVPIA+EV
Sbjct: 153 VVVIPAGVPRKPGMTRDDLFNINANIVKTLVEAVAENCPNAFIHIISNPVNSTVPIAAEV 212
Query: 546 LKKAGVYDPNRVLGVTTLDVVRAATFVGEINGVDPTSVAVP 668
LKK GVYDP ++ GVTTLDVVRA TFV + + V VP
Sbjct: 213 LKKKGVYDPKKLFGVTTLDVVRANTFVSQKKNLKLIDVDVP 253
>UniRef50_Q6BM17 Cluster: Malate dehydrogenase; n=4; Eukaryota|Rep:
Malate dehydrogenase - Debaryomyces hansenii (Yeast)
(Torulaspora hansenii)
Length = 346
Score = 188 bits (457), Expect = 1e-46
Identities = 96/163 (58%), Positives = 124/163 (76%), Gaps = 5/163 (3%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEE-----LSAA 350
IGQPL+LLLK NP V+ L+L+D+ GVAADLSH+ +PAKV+G++ + + A
Sbjct: 13 IGQPLSLLLKLNPQVSELSLFDVVNAN-GVAADLSHICSPAKVTGYQPSSKEDRDTIQKA 71
Query: 351 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 530
+ ++D+VVIPAGVPRKPGMTR DLFN NASI+RDI SI + P A + II+NPVNSTVP
Sbjct: 72 LVNSDLVVIPAGVPRKPGMTRADLFNINASIIRDIVGSIGKACPNAAILIISNPVNSTVP 131
Query: 531 IASEVLKKAGVYDPNRVLGVTTLDVVRAATFVGEINGVDPTSV 659
IA+EVLKK GV++P ++ GVTTLD VRA TF+GE+ PTS+
Sbjct: 132 IAAEVLKKLGVFNPKKLFGVTTLDSVRAETFLGELIKETPTSL 174
>UniRef50_A7SQS1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 254
Score = 186 bits (454), Expect = 3e-46
Identities = 87/121 (71%), Positives = 106/121 (87%)
Frame = +3
Query: 270 GVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVR 449
GVAADLSH++T AKV+ H+GP++L AA++ VV IPAGVPRKPGMTRDDLFNTNASIV+
Sbjct: 7 GVAADLSHISTRAKVTSHQGPDDLKAALEGCSVVAIPAGVPRKPGMTRDDLFNTNASIVK 66
Query: 450 DIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVRAATFVG 629
+++ + A++ PKAI+ II+NPVNSTVPIASEV KKAGVYDP R+LGVTTLD+VRA TFV
Sbjct: 67 NLSEACAKHCPKAIICIISNPVNSTVPIASEVYKKAGVYDPARILGVTTLDIVRAHTFVA 126
Query: 630 E 632
E
Sbjct: 127 E 127
>UniRef50_Q9Y7R8 Cluster: Malate dehydrogenase; n=13; Dikarya|Rep:
Malate dehydrogenase - Schizosaccharomyces pombe
(Fission yeast)
Length = 341
Score = 185 bits (451), Expect = 8e-46
Identities = 94/175 (53%), Positives = 122/175 (69%), Gaps = 2/175 (1%)
Frame = +3
Query: 123 KNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNT 302
++FSTTS R FK IGQPL++LLK N V+ LAL+DI PGVAAD+ H+NT
Sbjct: 19 RSFSTTSSRAFKVAVLGAGGGIGQPLSMLLKLNDKVSELALFDIRGA-PGVAADIGHINT 77
Query: 303 PAKVSGHKGPEE-LSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 479
+ V G+ ++ L A+ ADVV+IPAGVPRKPGMTRDDLF TNASIVRD+A + +
Sbjct: 78 TSNVVGYAPDDKGLEKALNGADVVIIPAGVPRKPGMTRDDLFATNASIVRDLAFAAGETC 137
Query: 480 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVRAATFVGEI-NG 641
P+A ++TNPVNSTVPI + L++ GV+ P + GVTTLD VRA+ F ++ NG
Sbjct: 138 PEAKYLVVTNPVNSTVPIFKKALERVGVHQPKHLFGVTTLDSVRASRFTSQVTNG 192
>UniRef50_Q9VU29 Cluster: Malate dehydrogenase; n=5;
Protostomia|Rep: Malate dehydrogenase - Drosophila
melanogaster (Fruit fly)
Length = 347
Score = 184 bits (447), Expect = 2e-45
Identities = 91/174 (52%), Positives = 116/174 (66%)
Frame = +3
Query: 147 RNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHK 326
R K IGQPL+LLLK NP ++ L+LYDI T GV DLSH+NT A V +
Sbjct: 26 RGLKVAVVGSVGGIGQPLSLLLKHNPQISTLSLYDIKNTT-GVGVDLSHINTRASVCPFE 84
Query: 327 GPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIIT 506
G L A+ AD+VVIPAG+PRKPGM R+DL + NAS+ ++A + ++ P A++A IT
Sbjct: 85 GKNGLKKAMDKADIVVIPAGLPRKPGMKREDLVDVNASVACEVAFAASEVCPGAMLAFIT 144
Query: 507 NPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVRAATFVGEINGVDPTSVAVP 668
NP+N VPI + +LK G YDPNR+ GVTTLDVVRA TFV +I VDP V +P
Sbjct: 145 NPINVIVPIVATILKAKGTYDPNRLFGVTTLDVVRAQTFVADILNVDPQKVNIP 198
>UniRef50_Q6FL22 Cluster: Malate dehydrogenase; n=1; Candida
glabrata|Rep: Malate dehydrogenase - Candida glabrata
(Yeast) (Torulopsis glabrata)
Length = 373
Score = 167 bits (407), Expect = 2e-40
Identities = 81/149 (54%), Positives = 111/149 (74%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDAD 365
+GQPL+LLLK N +++ LALYDI + GVA DLSH+NT A G+ +++ A+K A
Sbjct: 13 VGQPLSLLLKLNTMISELALYDIK-LAEGVATDLSHINTNADCVGYS-TDDIGQALKGAA 70
Query: 366 VVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEV 545
VVVIPAGVPR+PG+TRDDLF NA IV+++ ++A++ P A + II+NPVNS +P+A E
Sbjct: 71 VVVIPAGVPRRPGITRDDLFKLNAGIVKNLVSNVAKHCPNARLLIISNPVNSLIPVAVET 130
Query: 546 LKKAGVYDPNRVLGVTTLDVVRAATFVGE 632
LK+ GV+ V+GVTTLD+VRA TF+ E
Sbjct: 131 LKRCGVFQAGNVMGVTTLDLVRAETFLAE 159
>UniRef50_Q4Q3J3 Cluster: Malate dehydrogenase, putative; n=3;
Leishmania|Rep: Malate dehydrogenase, putative -
Leishmania major
Length = 331
Score = 167 bits (405), Expect = 3e-40
Identities = 84/173 (48%), Positives = 120/173 (69%), Gaps = 1/173 (0%)
Frame = +3
Query: 153 FKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHMNTPAKVSGHKG 329
FK IGQPLAL L QN V+ LALYDI V P GVA DLSH KV+G+
Sbjct: 9 FKVTVLGASGAIGQPLALALVQNKRVSELALYDI--VQPRGVAVDLSHFPRKVKVTGYP- 65
Query: 330 PEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITN 509
+ + A+ AD+V++ AG+PR+PGMT DDLFNTNA V +++ ++A+ APK+++AII+N
Sbjct: 66 TKWIHKALDGADLVLMSAGMPRRPGMTHDDLFNTNALTVNELSAAVARYAPKSVLAIISN 125
Query: 510 PVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVRAATFVGEINGVDPTSVAVP 668
P+NS VP+A+E L++AGVYDP ++ G+ +L+++RA +G+ G DP + VP
Sbjct: 126 PLNSMVPVAAETLQRAGVYDPRKLFGIISLNMMRARKMLGDFTGQDPEMLDVP 178
>UniRef50_P32419 Cluster: Malate dehydrogenase, peroxisomal; n=24;
Eukaryota|Rep: Malate dehydrogenase, peroxisomal -
Saccharomyces cerevisiae (Baker's yeast)
Length = 343
Score = 158 bits (383), Expect = 1e-37
Identities = 77/147 (52%), Positives = 103/147 (70%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDAD 365
+GQPL+LLLK +P V+ LALYDI G+ DLSH+NT + G+ + + + +A
Sbjct: 13 VGQPLSLLLKLSPYVSELALYDIR-AAEGIGKDLSHINTNSSCVGYD-KDSIENTLSNAQ 70
Query: 366 VVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEV 545
VV+IPAGVPRKPG+TRDDLF NA IV+ + ++ + AP A + +I+NPVNS VPIA E
Sbjct: 71 VVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAVET 130
Query: 546 LKKAGVYDPNRVLGVTTLDVVRAATFV 626
LKK G + P V+GVT LD+VRA TF+
Sbjct: 131 LKKMGKFKPGNVMGVTNLDLVRAETFL 157
>UniRef50_Q9VU28 Cluster: Malate dehydrogenase; n=3; Sophophora|Rep:
Malate dehydrogenase - Drosophila melanogaster (Fruit
fly)
Length = 349
Score = 156 bits (379), Expect = 4e-37
Identities = 77/174 (44%), Positives = 110/174 (63%)
Frame = +3
Query: 147 RNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHK 326
R K IGQPL+LLL++ P + LAL+D++ + G+A DLSH++ KV G
Sbjct: 21 RTLKVAVVGAGGGIGQPLSLLLRRCPGIDELALHDLSEMK-GIATDLSHISQTGKVIGFT 79
Query: 327 GPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIIT 506
G +EL +A+ ADVVV+ AG+PR PGM RD L N ++ +A +I+ +P+A +A IT
Sbjct: 80 GEKELESAVSGADVVVVAAGMPRLPGMQRDHLMAANGNVAVKVATAISNASPRAHLAFIT 139
Query: 507 NPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVRAATFVGEINGVDPTSVAVP 668
NPVN VP A+EVL G +D R+ G+TTLDVVR+ F+G+ + P V +P
Sbjct: 140 NPVNMIVPAAAEVLMAHGTFDSRRLFGITTLDVVRSKKFIGDSMNISPDDVNIP 193
>UniRef50_A7TL95 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 365
Score = 156 bits (379), Expect = 4e-37
Identities = 72/151 (47%), Positives = 108/151 (71%), Gaps = 1/151 (0%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDAD 365
IGQPL+LLLK NP V+ LALYDI+ +T GVA DLSH+NT + G+ E+ ++ ++
Sbjct: 13 IGQPLSLLLKLNPYVSDLALYDISDITAGVAKDLSHINTNSDSEGYNKDEDFKNLLEGSE 72
Query: 366 VVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAP-KAIVAIITNPVNSTVPIASE 542
+V++ AG+PRKPGMTRDDLF NA I++++ + A+ AP + II+NPVNS +P+ E
Sbjct: 73 LVIVTAGIPRKPGMTRDDLFKINAKIIQNLTVKYAKFAPVHCKLLIISNPVNSLIPVVIE 132
Query: 543 VLKKAGVYDPNRVLGVTTLDVVRAATFVGEI 635
LK G +P++V G+T LD++R+ TF+ ++
Sbjct: 133 TLKINGRLNPSQVFGITMLDIIRSQTFLNDL 163
>UniRef50_Q4QDF0 Cluster: Glycosomal malate dehydrogenase; n=9;
Trypanosomatidae|Rep: Glycosomal malate dehydrogenase -
Leishmania major
Length = 322
Score = 149 bits (362), Expect = 5e-35
Identities = 83/157 (52%), Positives = 105/157 (66%), Gaps = 8/157 (5%)
Frame = +3
Query: 186 IGQPLALLL-KQNPLVTRLALYDIAPVTPGVAADLSHM-NTPAKVS------GHKGPEEL 341
IGQ L+LLL +Q P + L+L+D+ GVAADLSH+ N +V GHK L
Sbjct: 13 IGQSLSLLLVRQLPYGSTLSLFDVVGAA-GVAADLSHVDNAGVQVKFAEGKIGHKRDPAL 71
Query: 342 SAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNS 521
+ K DV V+ AGVPRKPGMTRDDLF NA I+ D+ L+ A ++PKA+ I+TNPVNS
Sbjct: 72 AELAKGVDVFVMVAGVPRKPGMTRDDLFKINAGIILDLVLTCASSSPKAVFCIVTNPVNS 131
Query: 522 TVPIASEVLKKAGVYDPNRVLGVTTLDVVRAATFVGE 632
TV IA+E LK GVYD NR+LGV+ LD +RA F+ E
Sbjct: 132 TVAIAAEALKSLGVYDRNRLLGVSLLDGLRATCFINE 168
>UniRef50_Q5ENS5 Cluster: Malate dehydrogenase; n=1; Heterocapsa
triquetra|Rep: Malate dehydrogenase - Heterocapsa
triquetra (Dinoflagellate)
Length = 402
Score = 132 bits (320), Expect = 6e-30
Identities = 77/181 (42%), Positives = 104/181 (57%), Gaps = 9/181 (4%)
Frame = +3
Query: 153 FKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDI-APVTP--GVAADLSHMNTPAKVSGH 323
FK IGQPL LL+ +P V L ++D+ + P GVA DL H+ A V G+
Sbjct: 81 FKVCVCGGAGGIGQPLCLLMAMDPNVKELCVFDLNVAMVPAQGVATDLGHLEKKAAVKGY 140
Query: 324 ------KGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPK 485
K + L + +V+IPAG+PRKPG TRDDLF NA I + I + A+ P
Sbjct: 141 VMEVGQKPVDNLEECLTGCHLVLIPAGMPRKPGQTRDDLFKINADIAKGIVEACAKYCPD 200
Query: 486 AIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVRAATFVGEINGVDPTSVAV 665
A++ +I NPVNS VP +E+ KK G+ DP +++G+TTLDVVRA FV + P V V
Sbjct: 201 AMLGMIVNPVNSVVPAMAELYKKKGL-DPMKIVGITTLDVVRANKFVVRL-PAPPDRVNV 258
Query: 666 P 668
P
Sbjct: 259 P 259
>UniRef50_P22133 Cluster: Malate dehydrogenase, cytoplasmic; n=3;
Saccharomycetaceae|Rep: Malate dehydrogenase,
cytoplasmic - Saccharomyces cerevisiae (Baker's yeast)
Length = 377
Score = 132 bits (319), Expect = 8e-30
Identities = 86/185 (46%), Positives = 112/185 (60%), Gaps = 24/185 (12%)
Frame = +3
Query: 186 IGQPLALLLK---------QNPLVTR--LALYDI-APVTPGVAADLSHMNTPAKVSGHKG 329
IGQ L+LLLK N VT LALYD+ GV ADLSH++TP VS H
Sbjct: 25 IGQSLSLLLKAQLQYQLKESNRSVTHIHLALYDVNQEAINGVTADLSHIDTPISVSSHSP 84
Query: 330 PEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQ--NAPKAIVAII 503
+ + +A +VVIPAGVPRKPGMTRDDLFN NA I+ + SIA+ + K V +I
Sbjct: 85 AGGIENCLHNASIVVIPAGVPRKPGMTRDDLFNVNAGIISQLGDSIAECCDLSKVFVLVI 144
Query: 504 TNPVNSTVPI-ASEVLK------KAGVYDPNRVLGVTTLDVVRAATFVGEIN---GVDPT 653
+NPVNS VP+ S +LK +G+ R++GVT LD+VRA+TF+ EIN G+ P
Sbjct: 145 SNPVNSLVPVMVSNILKNHPQSRNSGI--ERRIMGVTKLDIVRASTFLREINIESGLTPR 202
Query: 654 SVAVP 668
++P
Sbjct: 203 VNSMP 207
>UniRef50_A3BMG8 Cluster: Putative uncharacterized protein; n=3;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 405
Score = 130 bits (314), Expect = 3e-29
Identities = 64/99 (64%), Positives = 76/99 (76%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDAD 365
IGQPL+LL+K +PLV+ L LYDIA V GV ADL H NTPAKV+G G EEL+ + D
Sbjct: 89 IGQPLSLLVKMSPLVSALHLYDIANVD-GVTADLGHCNTPAKVAGFTGKEELAGCLAGVD 147
Query: 366 VVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAP 482
VVVIPAGVPRKPGMTRDDLF NA IVR++ ++A +AP
Sbjct: 148 VVVIPAGVPRKPGMTRDDLFGINAGIVRELVEAVADHAP 186
Score = 40.7 bits (91), Expect = 0.032
Identities = 24/55 (43%), Positives = 30/55 (54%)
Frame = +2
Query: 500 HHKPC*LYSAYCL*SAQEGGSVRPEPRARRHHSGRSPRCHLRRRDQWRGPDLRRR 664
H +P L+ A A+ G VRP RRH +GR R H+RR D+ GP RRR
Sbjct: 193 HLQPGELHRADRRRGAEAEGRVRPAEAVRRHDAGRRARQHVRRGDE--GPPARRR 245
>UniRef50_UPI0000D571DB Cluster: PREDICTED: similar to CG7998-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG7998-PA - Tribolium castaneum
Length = 376
Score = 126 bits (305), Expect = 4e-28
Identities = 63/160 (39%), Positives = 102/160 (63%)
Frame = +3
Query: 189 GQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADV 368
G+ ++L+LKQ+P + L LYD + G A DL++++T +V+ G +++ A+ +++
Sbjct: 41 GKSVSLMLKQSPFIDELCLYDTQSLE-GFANDLNYVDTKCRVTSFFGNKDIQKALTKSNI 99
Query: 369 VVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVL 548
+V+ + LF+ NA IV+D+A SIA+ +PK+ VAI P+NS VP+ SE++
Sbjct: 100 IVVLSCCHAAEPTNYASLFDRNAPIVKDLATSIAKFSPKSTVAIGVEPINSVVPMFSEIM 159
Query: 549 KKAGVYDPNRVLGVTTLDVVRAATFVGEINGVDPTSVAVP 668
KK G Y+P + G+TT+DVVR FV EI G++P V VP
Sbjct: 160 KKYGHYNPYSIFGITTVDVVRTNKFVAEILGLEPECVTVP 199
>UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep:
ADL164Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 381
Score = 126 bits (305), Expect = 4e-28
Identities = 86/189 (45%), Positives = 108/189 (57%), Gaps = 26/189 (13%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVT--------RLALYDIAP-VTPGVAADLSHMNTPAKVSGH----- 323
IGQPL+LLLK LALYD+A GVAADLSH+NTP +VS H
Sbjct: 35 IGQPLSLLLKTQLAQVLGDANASLELALYDVAADALAGVAADLSHVNTPVEVSHHVPSSR 94
Query: 324 KGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQ--NAPKAIVA 497
+ E L A+ A VVVIPAGVPRKPGMTRDDL N NA I++ +A IA + K V
Sbjct: 95 EDEEALREALTGASVVVIPAGVPRKPGMTRDDLININAGIIKTLAKGIAGACDLEKVFVL 154
Query: 498 IITNPVNSTVPI-ASEVLKKAGVYD------PNRVLGVTTLDVVRAATFV---GEINGVD 647
+I+NPVNS VP+ ++++ A RV GVT LD+VRA+ FV GE+
Sbjct: 155 VISNPVNSLVPVMVRQLIRHAEAKQAPHAGVERRVFGVTQLDMVRASAFVRSLGELGNEV 214
Query: 648 PTSVAVPRH 674
P+ + H
Sbjct: 215 PSVPVIGGH 223
>UniRef50_UPI00005A0834 Cluster: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor; n=1; Canis lupus
familiaris|Rep: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor - Canis
familiaris
Length = 245
Score = 125 bits (301), Expect = 1e-27
Identities = 54/84 (64%), Positives = 69/84 (82%)
Frame = +3
Query: 390 PRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYD 569
PRKPGMTRDDLFNTNAS+V + AQ+ P+A++ +I+NPVNST+PIA+EV KK G YD
Sbjct: 61 PRKPGMTRDDLFNTNASVVATPTAACAQHCPEAMICVISNPVNSTIPIATEVFKKHGAYD 120
Query: 570 PNRVLGVTTLDVVRAATFVGEING 641
PN++ VTTLD+VRA TF+ E+NG
Sbjct: 121 PNKIFRVTTLDIVRANTFIAELNG 144
>UniRef50_A7TSF5 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 387
Score = 122 bits (293), Expect = 1e-26
Identities = 74/153 (48%), Positives = 97/153 (63%), Gaps = 6/153 (3%)
Frame = +3
Query: 186 IGQPLALLLK-----QNPLVTRLALYDI-APVTPGVAADLSHMNTPAKVSGHKGPEELSA 347
IGQ L+LLL+ N LAL+D+ V GV ADLSH+NT K+S H + L
Sbjct: 52 IGQSLSLLLRTSLQNNNDNQLHLALFDVNMKVLNGVHADLSHVNTNMKLSLH---DNLRD 108
Query: 348 AIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTV 527
++ D+++V+IPAGVPRKPGMTRDDLFN NA I++ IA + V +I+NPVNS +
Sbjct: 109 SLVDSNLVIIPAGVPRKPGMTRDDLFNINAGIIKGIAQELNTIDSTPFVLLISNPVNSLL 168
Query: 528 PIASEVLKKAGVYDPNRVLGVTTLDVVRAATFV 626
P+ VL VY R G+T LD+VRA+TFV
Sbjct: 169 PVLQSVLN--DVY-LGRCFGITELDLVRASTFV 198
>UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces
cerevisiae YOL126c MDH2 malate dehydrogenase; n=1;
Kluyveromyces lactis|Rep: Similar to sp|P22133
Saccharomyces cerevisiae YOL126c MDH2 malate
dehydrogenase - Kluyveromyces lactis (Yeast) (Candida
sphaerica)
Length = 404
Score = 120 bits (288), Expect = 4e-26
Identities = 75/181 (41%), Positives = 107/181 (59%), Gaps = 20/181 (11%)
Frame = +3
Query: 186 IGQPLALLLKQN-----PLVT----RLALYDI-APVTPGVAADLSHMNTPAKVSGHKGPE 335
IGQ L+LLLK N P T RL+LYD+ G AADLSH++TP + H +
Sbjct: 58 IGQSLSLLLKSNAGFLLPHETSTHIRLSLYDVNKDAIVGTAADLSHIDTPITTTAHYPDD 117
Query: 336 E---LSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQ--NAPKAIVAI 500
+ + +A VV+IPAGVPRKPGM+RDDL NA I++ + IA+ + K V +
Sbjct: 118 SNGGIGQCLSNASVVIIPAGVPRKPGMSRDDLIGVNAKIIKSLGEDIAKYCDLNKVHVLV 177
Query: 501 ITNPVNSTVPIASEVLKKAGVYD----PNRVLGVTTLDVVRAATFVGEINGV-DPTSVAV 665
I+NP+NS VP+ + L ++ +RV G+T LD+VR++TFV ++NG TS +
Sbjct: 178 ISNPINSLVPLLTNTLIRSDANGNSNIESRVYGITQLDLVRSSTFVQQLNGFKSNTSPVI 237
Query: 666 P 668
P
Sbjct: 238 P 238
>UniRef50_Q86DP2 Cluster: Malate dehydrogenase; n=11; Fungi/Metazoa
group|Rep: Malate dehydrogenase - Plicopurpura patula
Length = 229
Score = 118 bits (285), Expect = 1e-25
Identities = 58/84 (69%), Positives = 65/84 (77%)
Frame = +3
Query: 417 DLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTT 596
DLFNTNA IVRD+ IA+ P A++ IITNPVNSTVPIASEVLKK GVYDP RV GVTT
Sbjct: 1 DLFNTNAGIVRDLTDRIAKVCPTAMLGIITNPVNSTVPIASEVLKKRGVYDPKRVFGVTT 60
Query: 597 LDVVRAATFVGEINGVDPTSVAVP 668
LDVVR+ TF+ E G+D T VP
Sbjct: 61 LDVVRSNTFIAEAKGLDVTKTNVP 84
>UniRef50_UPI0000DB76D8 Cluster: PREDICTED: similar to CG7998-PA;
n=2; Apis mellifera|Rep: PREDICTED: similar to CG7998-PA
- Apis mellifera
Length = 333
Score = 111 bits (267), Expect = 2e-23
Identities = 55/161 (34%), Positives = 100/161 (62%), Gaps = 1/161 (0%)
Frame = +3
Query: 189 GQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEE-LSAAIKDAD 365
G L+L LKQ+PL+ LA++D T G+A DL++++T KVS PE+ L ++ A
Sbjct: 13 GNCLSLFLKQSPLIDELAIFDNNSSTYGLALDLNYIDTKCKVSTCNHPEKCLEETLQGAK 72
Query: 366 VVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEV 545
+V+I V + +++ +NA I+ D+ +I + +P+A++AI+ NP+NS +P+ E+
Sbjct: 73 IVMI---VTDRTSNESNEVLKSNAIILSDLLPNIIKFSPQAMLAIVMNPINSLIPLTMEM 129
Query: 546 LKKAGVYDPNRVLGVTTLDVVRAATFVGEINGVDPTSVAVP 668
KKAG+Y+ NR+ GV + ++A +F ++ ++P +P
Sbjct: 130 YKKAGIYEYNRIFGVMNFECLKANSFTADLINIEPECTMIP 170
>UniRef50_UPI0000D55CD8 Cluster: PREDICTED: similar to Malate
DeHydrogenase family member (mdh-1); n=1; Tribolium
castaneum|Rep: PREDICTED: similar to Malate
DeHydrogenase family member (mdh-1) - Tribolium
castaneum
Length = 374
Score = 107 bits (257), Expect = 2e-22
Identities = 61/161 (37%), Positives = 89/161 (55%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDAD 365
+G LALLLKQN + L L+D T A DL+ ++T K+ + L AI A
Sbjct: 40 VGSNLALLLKQNLDIYELRLFDEENNTNAFACDLNEIDTRTKLKSFSC-KSLKNAIVGAH 98
Query: 366 VVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEV 545
VV+ G KPG ++ +LF+ N VR++A+ +A+ P+AI I PV + VP+ SE
Sbjct: 99 VVISTGGCQEKPGSSQRELFDKNLDNVRNVAMFLAEFNPEAIYCIAKPPVEALVPMVSEE 158
Query: 546 LKKAGVYDPNRVLGVTTLDVVRAATFVGEINGVDPTSVAVP 668
KKA YDP +++GV T+ + A TF+ E +P V P
Sbjct: 159 YKKAETYDPRKIIGVATVASMIANTFIAEHTNQNPADVLCP 199
>UniRef50_Q017A6 Cluster: Malate dehydrogenase; n=2; cellular
organisms|Rep: Malate dehydrogenase - Ostreococcus tauri
Length = 477
Score = 106 bits (255), Expect = 4e-22
Identities = 51/88 (57%), Positives = 64/88 (72%)
Frame = +3
Query: 405 MTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVL 584
MTRDDLF N IV+ + +IA N P A++ +I+NPVNSTVPIA+EVLK G YDP ++
Sbjct: 1 MTRDDLFAINGGIVKGLVEAIADNCPNAMINMISNPVNSTVPIAAEVLKAKGKYDPKKLF 60
Query: 585 GVTTLDVVRAATFVGEINGVDPTSVAVP 668
GVTTLDVVRA TF E G++ + V VP
Sbjct: 61 GVTTLDVVRAKTFYAEKAGLETSKVDVP 88
>UniRef50_UPI0000D56DC5 Cluster: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor; n=1; Tribolium
castaneum|Rep: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor - Tribolium
castaneum
Length = 349
Score = 96.3 bits (229), Expect = 6e-19
Identities = 55/183 (30%), Positives = 94/183 (51%)
Frame = +3
Query: 120 AKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMN 299
+++F + Q++ + +GQ LA L+KQNP ++ L L + V +A D +H +
Sbjct: 11 SRHFCSKPQKHVQVCILGADTLLGQSLAFLIKQNPAISGLHLQGTSKVE-SMALDFNHFD 69
Query: 300 TPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 479
T +V + + +S ++K AD+VV+ M+ L V +A + A+ A
Sbjct: 70 TRCRVHSYYDMDSVSKSVKCADIVVMLGLNTSTSKMSIPKLVMAEGVRVAKLAETCAKYA 129
Query: 480 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVRAATFVGEINGVDPTSV 659
PKA++ + P++ T+PI +EV K++ Y P R+LG L V+A G +DP V
Sbjct: 130 PKAVIVVAVTPISVTLPIVAEVYKQSDWYHPGRLLGSAALAEVKANAIAGHYQTLDPQMV 189
Query: 660 AVP 668
VP
Sbjct: 190 HVP 192
>UniRef50_Q4Q3J5 Cluster: Malate dehydrogenase, putative; n=5;
Trypanosomatidae|Rep: Malate dehydrogenase, putative -
Leishmania major
Length = 342
Score = 95.9 bits (228), Expect = 8e-19
Identities = 60/184 (32%), Positives = 94/184 (51%), Gaps = 5/184 (2%)
Frame = +3
Query: 132 STTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTP----GVAADLSHMN 299
S T+ + K +GQPL+LLLK NP V L + A G+AADLSH++
Sbjct: 8 SLTALKKGKVVLFGCSNAVGQPLSLLLKMNPHVEELVCCNTAADDDVPGSGIAADLSHID 67
Query: 300 TPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKP-GMTRDDLFNTNASIVRDIALSIAQN 476
T KV + A ++DA ++++ G RD A +R + ++A +
Sbjct: 68 TLPKVHYATDEGQWPALLRDAQLILVCFGSSFDLLREDRDIALKAAAPTMRRVMAAVASS 127
Query: 477 APKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVRAATFVGEINGVDPTS 656
VA++++PVN+ P +E+LK +G +DP ++ GVTTLDV+R V ++P
Sbjct: 128 DTTGNVAVVSSPVNALTPFCAELLKASGKFDPRKLFGVTTLDVIRTRKLVAGTLHMNPYD 187
Query: 657 VAVP 668
V VP
Sbjct: 188 VNVP 191
>UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2;
Toxoplasma gondii|Rep: Mitochondrial
malate-dehydrogenase - Toxoplasma gondii
Length = 470
Score = 83.8 bits (198), Expect = 3e-15
Identities = 59/152 (38%), Positives = 82/152 (53%), Gaps = 3/152 (1%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHMNTPAKVSGH-KGPEELSAAIKD 359
IG LALL L + ++D+ P G DL + + V +G + S +KD
Sbjct: 168 IGATLALLSAVKELGD-VVMFDVVQDLPQGKCLDLYQLTPISGVDVRFEGSNDYSV-LKD 225
Query: 360 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 539
ADV+++ AGVPRKPGM+RDDL NA I+ + +I Q P A V ITNP++ V I
Sbjct: 226 ADVIIVTAGVPRKPGMSRDDLLAINAKIMGQVGEAIKQYCPNAFVICITNPLDVMVYILR 285
Query: 540 EVLKKAGVYDPNRVLGVT-TLDVVRAATFVGE 632
E K G+ P++V G+ LD R TF+ E
Sbjct: 286 E---KCGL-PPHKVCGMAGVLDSARLRTFLSE 313
>UniRef50_Q8ZVB2 Cluster: Malate dehydrogenase; n=14;
Thermoprotei|Rep: Malate dehydrogenase - Pyrobaculum
aerophilum
Length = 309
Score = 83.8 bits (198), Expect = 3e-15
Identities = 53/161 (32%), Positives = 89/161 (55%), Gaps = 3/161 (1%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHMNTPAKVS-GHKGPEELSAAIKD 359
+G A+++ L ++ L DI P G A D++HM++ + + G E I+
Sbjct: 10 VGTAAAVIMGLMKLDNKILLIDIVKGLPQGEALDMNHMSSILGLDVEYVGSNEYKD-IEG 68
Query: 360 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 539
+D++++ AG+PRKPGMTR+ L NA IV +I I + AP +IV + TNP+++ +
Sbjct: 69 SDLIIVTAGLPRKPGMTREQLLEANAKIVAEIGREIKKYAPDSIVILTTNPLDA----MT 124
Query: 540 EVLKKAGVYDPNRVLGVT-TLDVVRAATFVGEINGVDPTSV 659
V+ KA + RV+G + LD R A + + G+ P S+
Sbjct: 125 YVMWKATGFPRERVIGFSGVLDAGRLAFYAAKKLGISPASI 165
>UniRef50_P16115 Cluster: L-lactate dehydrogenase; n=4;
Thermotogaceae|Rep: L-lactate dehydrogenase - Thermotoga
maritima
Length = 319
Score = 82.2 bits (194), Expect = 1e-14
Identities = 56/162 (34%), Positives = 85/162 (52%), Gaps = 2/162 (1%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAPV-TPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 362
+G A L + L D+ G A DL H TP + + A +K +
Sbjct: 11 VGSSTAFALLMKGFAREMVLIDVDKKRAEGDALDLIH-GTPFTRRANIYAGDY-ADLKGS 68
Query: 363 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 542
DVV++ AGVP+KPG TR L NA ++++IA ++++ AP +IV ++TNPV+ +
Sbjct: 69 DVVIVAAGVPQKPGETRLQLLGRNARVMKEIARNVSKYAPDSIVIVVTNPVD---VLTYF 125
Query: 543 VLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSVAV 665
LK++G+ DP +V G T LD R T + + G P SV V
Sbjct: 126 FLKESGM-DPRKVFGSGTVLDTARLRTLIAQHCGFSPRSVHV 166
>UniRef50_UPI00015B4591 Cluster: PREDICTED: similar to mitochondrial
malate dehydrogenase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to mitochondrial malate dehydrogenase
- Nasonia vitripennis
Length = 299
Score = 81.4 bits (192), Expect = 2e-14
Identities = 42/156 (26%), Positives = 81/156 (51%), Gaps = 1/156 (0%)
Frame = +3
Query: 204 LLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPA 383
+LLKQNP + + L D D+ H++T + H + +++ D+V +
Sbjct: 1 MLLKQNPAIKEIRLIDTDNSLMSPVCDMRHIDTSTTIR-HFRKNSILDGLRNTDIVALMD 59
Query: 384 GVPRKPGMTRDDL-FNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAG 560
G + F +++ V+ +A + PKA+VA+ T+PV +T+P+ SE+ K +G
Sbjct: 60 ETDFMMGNKGPFMQFVNSSNYVKSVAECMINVCPKALVAVFTHPVTATLPLVSEIYKYSG 119
Query: 561 VYDPNRVLGVTTLDVVRAATFVGEINGVDPTSVAVP 668
+DPNR+ G L+ +R + + ++P+ ++VP
Sbjct: 120 DWDPNRIFGSAALESMRISAMTATLLDLNPSFISVP 155
>UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3;
Actinomycetales|Rep: Lactate/malate dehydrogenase -
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 330
Score = 81.4 bits (192), Expect = 2e-14
Identities = 59/160 (36%), Positives = 82/160 (51%), Gaps = 8/160 (5%)
Frame = +3
Query: 189 GQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHMNT----PAKVSGHK-GPEELS-A 347
G A L + + + L DI P G+A D++ KV G P+
Sbjct: 24 GSTTAQRLAEYDIFETVVLTDIIEGRPEGLALDINQSRPIEGFETKVIGKTTSPDGAGYE 83
Query: 348 AIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTV 527
I DA +V+I AGVPRKPGM+R DL TNA IVR +A +IA+ AP A+V +++NP++
Sbjct: 84 VIADASIVIITAGVPRKPGMSRMDLLETNARIVRGVAENIAKYAPSAVVIVVSNPLDEMT 143
Query: 528 PIASEVLKKAGVYDPNRVLG-VTTLDVVRAATFVGEINGV 644
+ V + NRV+G LD R + FV E GV
Sbjct: 144 ALTQLVTG----FPKNRVMGQAGMLDTARFSHFVAEELGV 179
>UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|Rep:
Malate dehydrogenase 1 - Aquifex aeolicus
Length = 335
Score = 79.8 bits (188), Expect = 6e-14
Identities = 50/128 (39%), Positives = 74/128 (57%), Gaps = 3/128 (2%)
Frame = +3
Query: 285 LSHMNTPAKVSGHK-GPE-ELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIA 458
L+ M+ A+V G+ PE E ++ +D+VVI AG PR+PGM+R+DL N I+ IA
Sbjct: 59 LAAMDIDARVEGYTVTPEGEGYEPLEGSDIVVITAGFPRRPGMSREDLLEANIRIISVIA 118
Query: 459 LSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVT-TLDVVRAATFVGEI 635
I + AP AIV ++TNPV+ +A ++L + NRV+G+ LD R TF+ E
Sbjct: 119 DRIKRYAPDAIVIVVTNPVDVMTYVAYKLLN----FPKNRVMGMAGVLDSARFKTFISEE 174
Query: 636 NGVDPTSV 659
V P +
Sbjct: 175 LMVSPKDI 182
>UniRef50_A6Q7S2 Cluster: Malate dehydrogenase, NAD-dependent; n=1;
Sulfurovum sp. NBC37-1|Rep: Malate dehydrogenase,
NAD-dependent - Sulfurovum sp. (strain NBC37-1)
Length = 320
Score = 79.0 bits (186), Expect = 1e-13
Identities = 59/157 (37%), Positives = 83/157 (52%), Gaps = 9/157 (5%)
Frame = +3
Query: 189 GQPLALLLKQNPLVTRLAL----YDIAPVTPGVAADLSHMNTPAK----VSGHKGPEELS 344
G +A +L N + L YD+A G A D+S A+ V KGPE++
Sbjct: 16 GSTVAFILAMNGSCHHVMLRGRNYDVAK---GKALDMSQAANAARQHTIVKAAKGPEDME 72
Query: 345 AAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNST 524
+ DVV+I AG PR PGM+RDDL NA IV+ + I + AP AIV +++NP++
Sbjct: 73 GS----DVVIITAGAPRTPGMSRDDLLFKNADIVKCYSREIKEYAPDAIVIVVSNPLDVM 128
Query: 525 VPIASEVLKKAGVYDPNRVLGVT-TLDVVRAATFVGE 632
+A LK+ G + RVLG+ LD R A F+ E
Sbjct: 129 TYVA---LKETG-FPRQRVLGMAGILDAARMAHFIYE 161
>UniRef50_Q3J7E7 Cluster: Malate dehydrogenase; n=5;
Gammaproteobacteria|Rep: Malate dehydrogenase -
Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
Length = 311
Score = 77.8 bits (183), Expect = 2e-13
Identities = 55/165 (33%), Positives = 85/165 (51%), Gaps = 6/165 (3%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSH----MNTPAKVSGHKGPEELSAA 350
+G+ A L +N L L L D V G A D+ + A+V+G E
Sbjct: 14 VGEATAQFLVKNELCRELVLLDAQEGVAQGAALDIQQSAPLFDFDARVTGSTNYE----L 69
Query: 351 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 530
I D+D+VVI AG PRKPGM+R D+ ++N I+ DI ++ + AP+++V I+TNPV+
Sbjct: 70 IADSDLVVITAGKPRKPGMSRSDVLDSNLPIITDIMNNVMRFAPQSLVMIVTNPVD---V 126
Query: 531 IASEVLKKAGVYDPNRVLG-VTTLDVVRAATFVGEINGVDPTSVA 662
+ + G +D RV G LD R A+F+ G+ ++
Sbjct: 127 LTYHAWRHCG-WDRARVFGQAGVLDSARMASFIAGETGLSVKDIS 170
>UniRef50_UPI00015B5ACF Cluster: PREDICTED: similar to
ENSANGP00000020184; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000020184 - Nasonia
vitripennis
Length = 352
Score = 77.4 bits (182), Expect = 3e-13
Identities = 54/181 (29%), Positives = 88/181 (48%), Gaps = 2/181 (1%)
Frame = +3
Query: 132 STTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAK 311
++++ RN K G+ LAL LKQ+ L+ LA+YD P T G+ +LSHM++ +
Sbjct: 29 TSSNSRNLKVAIVGATGQTGRSLALCLKQSALIDELAVYDSHP-TRGLLLELSHMDSRCR 87
Query: 312 VSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRD-DLFNTNASIVRDIALSIAQNAPKA 488
SA D+ G + +T D + A + I + PKA
Sbjct: 88 TIVEDEASTTSACNGKRDLERALTGA-KIVAITLDGESIREEAEYLEKILSGLLGCCPKA 146
Query: 489 IVAIITNPVNSTVPIASEVLKKAGVYD-PNRVLGVTTLDVVRAATFVGEINGVDPTSVAV 665
+VA+++ VNS VP+ E+ K+AG+++ +R+ GV +L RA E + P +V
Sbjct: 147 LVALVSRRVNSLVPMLYELYKRAGLFEASSRIFGVVSLFATRANGLAAETLKIQPELSSV 206
Query: 666 P 668
P
Sbjct: 207 P 207
>UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular
organisms|Rep: Malate dehydrogenase - Silicibacter
pomeroyi
Length = 320
Score = 77.0 bits (181), Expect = 4e-13
Identities = 54/151 (35%), Positives = 75/151 (49%), Gaps = 2/151 (1%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHMNTPAKVSGHKGPEELSAAIKDA 362
IG LA L+ L + L+DIA TP G A D++ + A I A
Sbjct: 14 IGGTLAHLVALKELGD-VVLFDIAEGTPEGKALDIAESGPSEGFDAKLKGTQSYADIAGA 72
Query: 363 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 542
DV ++ AGVPRKPGM+RDDL N +++ + I NAP A V ITNP+++ V
Sbjct: 73 DVCIVTAGVPRKPGMSRDDLLGINLKVMKSVGEGIRDNAPDAFVICITNPLDAMV----W 128
Query: 543 VLKKAGVYDPNRVLGVT-TLDVVRAATFVGE 632
L++ N+V G+ LD R F+ E
Sbjct: 129 ALQQFSGLPANKVCGMAGVLDSARFRHFLAE 159
>UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|Rep:
Malate dehydrogenase - Plasmodium falciparum
Length = 313
Score = 76.6 bits (180), Expect = 5e-13
Identities = 41/100 (41%), Positives = 58/100 (58%), Gaps = 1/100 (1%)
Frame = +3
Query: 237 LALYDIAPVTP-GVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTR 413
L LYD+ P P G A DL H +T V+ + IKDAD++VI AGV RK GMTR
Sbjct: 28 LILYDVVPGIPQGKALDLKHFSTILGVNRNILGTNQIEDIKDADIIVITAGVQRKEGMTR 87
Query: 414 DDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 533
+DL N I++ +A S+ + KA V ++NP++ V +
Sbjct: 88 EDLIGVNGKIMKSVAESVKLHCSKAFVICVSNPLDIMVNV 127
>UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;
Ignicoccus hospitalis KIN4/I|Rep: malate dehydrogenase
(NAD) - Ignicoccus hospitalis KIN4/I
Length = 311
Score = 76.2 bits (179), Expect = 7e-13
Identities = 51/152 (33%), Positives = 75/152 (49%), Gaps = 2/152 (1%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 362
+G A + P V R+ L D P ++ GV D+ H + S + + +++A
Sbjct: 16 VGATFAYTMAIVPGVARMVLVDAVPGLSKGVMEDIKHAAAVFRRSIQVEAYDDVSKVENA 75
Query: 363 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 542
D +VI AG PRK M+R DL NA I+RDI + P A +ITNPV+ I S+
Sbjct: 76 DAIVITAGKPRKADMSRRDLAKVNAQIIRDIGDKLRDRNPGAFYMVITNPVDVMTMILSD 135
Query: 543 VLKKAGVYDPNRVLGV-TTLDVVRAATFVGEI 635
V+ G V+G T+LD R + V E+
Sbjct: 136 VIGNKGT-----VIGTGTSLDTYRFRSAVSEL 162
>UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Rep:
Malate dehydrogenase - Brucella melitensis
Length = 320
Score = 75.8 bits (178), Expect = 9e-13
Identities = 48/134 (35%), Positives = 71/134 (52%), Gaps = 2/134 (1%)
Frame = +3
Query: 237 LALYDIAPVTP-GVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTR 413
+ L+DIA TP G D++ + AAI+ ADVV++ AGVPRKPGM+R
Sbjct: 30 VVLFDIAEGTPQGKGLDIAESSPVDGFDAKFTGANDYAAIEGADVVIVTAGVPRKPGMSR 89
Query: 414 DDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVT 593
DDL N ++ + I + AP+A V ITNP+++ V L+K ++V+G+
Sbjct: 90 DDLLGINLKVMEQVGAGIKKYAPEAFVICITNPLDAMV----WALQKFSGLPAHKVVGMA 145
Query: 594 -TLDVVRAATFVGE 632
LD R F+ E
Sbjct: 146 GVLDSARFRYFLSE 159
>UniRef50_Q64P62 Cluster: Malate dehydrogenase; n=28;
Bacteroidetes|Rep: Malate dehydrogenase - Bacteroides
fragilis
Length = 313
Score = 75.8 bits (178), Expect = 9e-13
Identities = 55/164 (33%), Positives = 90/164 (54%), Gaps = 6/164 (3%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHMNTPAKVSGHK----GPEELSAA 350
+G A +L N + + + D+ V+ G A D+ M T A++ G G A
Sbjct: 12 VGATCANVLAFNEVADEVVMLDVKEGVSEGKAMDM--MQT-AQLLGFDTTIVGCTNDYAQ 68
Query: 351 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 530
++DVVVI +G+PRKPGMTR++L NA IV+ +A ++ + +P AI+ +I+NP+++
Sbjct: 69 TANSDVVVITSGIPRKPGMTREELIGVNAGIVKSVAENLLKYSPNAIIVVISNPMDTMTY 128
Query: 531 IASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
+A LK G+ NRV+G+ LD R F+ + G + V
Sbjct: 129 LA---LKSLGL-PKNRVIGMGGALDSSRFKYFLSQALGCNANEV 168
>UniRef50_A0RXX8 Cluster: Malate/L-lactate dehydrogenase; n=1;
Cenarchaeum symbiosum|Rep: Malate/L-lactate
dehydrogenase - Cenarchaeum symbiosum
Length = 302
Score = 75.4 bits (177), Expect = 1e-12
Identities = 51/161 (31%), Positives = 83/161 (51%), Gaps = 3/161 (1%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHMNTPAKVSGH-KGPEELSAAIKD 359
+G A+ L + + L DI P G A D++HM + +G + S ++
Sbjct: 10 VGGDAAMFCALRRLDSEILLLDIVEGLPQGEAMDINHMLAEQGIDTEVRGSNDYSD-MEG 68
Query: 360 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 539
+D+VV+ AG RKPGMTR DL NA IV+ + + ++A +++ +TNP++ PI
Sbjct: 69 SDIVVVVAGAGRKPGMTRMDLLKINAGIVKGVVEKVKEHAKDSMIIPVTNPLD---PITY 125
Query: 540 EVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
K +G ++ NRV G+ LD+ R F+ E G S+
Sbjct: 126 IAYKTSG-FEKNRVFGMGGMLDLSRFRQFIHEATGYSRDSI 165
>UniRef50_A2SNY0 Cluster: Malate/lactate dehydrogenases-like
protein; n=1; Methylibium petroleiphilum PM1|Rep:
Malate/lactate dehydrogenases-like protein - Methylibium
petroleiphilum (strain PM1)
Length = 432
Score = 74.5 bits (175), Expect = 2e-12
Identities = 50/160 (31%), Positives = 79/160 (49%), Gaps = 2/160 (1%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 362
+G AL L ++ L + +AL D+ P + G+A D+ H S + A+ A
Sbjct: 134 VGAMTALRLAESDLFSEVALVDVVPGLAAGLALDMWHGAGLYGFSTRLSGSDDLVALAGA 193
Query: 363 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 542
+ +VI AG PR+PGM+R DL NA I+ + I +AP + + I++NP+ +A++
Sbjct: 194 EYIVITAGKPRQPGMSRTDLTVVNAEIMTSVCRGIRTHAPNSTLVIVSNPLEEMTHLAAQ 253
Query: 543 VLKKAGVYDPNRVLGVT-TLDVVRAATFVGEINGVDPTSV 659
+ G + RVLG+ LD R VG P V
Sbjct: 254 ---QTG-FPEERVLGMAGVLDSARFCALVGLTGKARPQEV 289
>UniRef50_A7DRG3 Cluster: Lactate/malate dehydrogenase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
Lactate/malate dehydrogenase - Candidatus Nitrosopumilus
maritimus SCM1
Length = 304
Score = 73.7 bits (173), Expect = 4e-12
Identities = 51/160 (31%), Positives = 83/160 (51%), Gaps = 2/160 (1%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHMNTPAKVSGHKGPEELSAAIKDA 362
+G AL L ++ L D+A P G A D++HM + + +K +
Sbjct: 10 VGGDAALFSALKRLDDQILLLDVAEGLPQGEAMDINHMLSEQGIDVEVKGSNNFEDMKGS 69
Query: 363 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 542
++VV+ AG RKPGMTR DL NASIV+ + ++ + A +++ +TNP++ P+A
Sbjct: 70 NIVVVVAGSGRKPGMTRMDLLKINASIVKSVVENVKKYADDSMIIPVTNPLD---PMAYI 126
Query: 543 VLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
K +G +D +RV G+ LD+ R F+ E G S+
Sbjct: 127 TYKVSG-FDRSRVFGMGGMLDLSRFRQFIHEATGHSRDSI 165
>UniRef50_O08349 Cluster: Malate dehydrogenase; n=1; Archaeoglobus
fulgidus|Rep: Malate dehydrogenase - Archaeoglobus
fulgidus
Length = 294
Score = 73.3 bits (172), Expect = 5e-12
Identities = 44/116 (37%), Positives = 68/116 (58%), Gaps = 5/116 (4%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHMNTPAKVSGHKGPEELSAA---- 350
+G A N V +AL DIA + G A DL+H A K P+ + A
Sbjct: 11 VGSTSAFTCLLNLDVDEIALVDIAEDLAVGEAMDLAH----AAAGIDKYPKIVGGADYSL 66
Query: 351 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 518
+K ++++V+ AG+ RKPGMTR DL + NA I++DIA I +NAP++ + ++TNP++
Sbjct: 67 LKGSEIIVVTAGLARKPGMTRLDLAHKNAGIIKDIAKKIVENAPESKILVVTNPMD 122
>UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD binding
domain protein; n=2; Campylobacter|Rep: Lactate/malate
dehydrogenase, NAD binding domain protein -
Campylobacter curvus 525.92
Length = 297
Score = 72.9 bits (171), Expect = 6e-12
Identities = 53/162 (32%), Positives = 83/162 (51%), Gaps = 3/162 (1%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHMNTP-AKVSGHKGPEELSAAIKD 359
+G +A L + +AL DI V A D++ G ++ A I+
Sbjct: 11 VGASIAYALAMRGVCDEIALVDIFGDVARAKAIDIAQAGCVFCGCLSTAGGDDF-ALIEA 69
Query: 360 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 539
+D+VV+ AG PRK G TR+DL NA +V+ A +IA+ AP AIV I+TNP++ V
Sbjct: 70 SDIVVVTAGSPRKEGQTREDLLLKNAQVVKQTAQNIAKFAPNAIVIIVTNPLDVMV---W 126
Query: 540 EVLKKAGVYDPNRVLGVT-TLDVVRAATFVGEINGVDPTSVA 662
VL+ +G +D +RV+G+ LD R + + + V+
Sbjct: 127 TVLRYSG-FDRSRVIGMAGELDSARCRYEIASLKDISAKDVS 167
>UniRef50_Q979N9 Cluster: Malate dehydrogenase; n=4;
Thermoplasmatales|Rep: Malate dehydrogenase -
Thermoplasma volcanium
Length = 325
Score = 72.9 bits (171), Expect = 6e-12
Identities = 34/95 (35%), Positives = 63/95 (66%), Gaps = 1/95 (1%)
Frame = +3
Query: 351 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 530
++ +DV+V+ AG+ RKPGM+R+DLF+ N I+ D++ +I + +P +I+ +++NP +
Sbjct: 74 MEGSDVIVVTAGMARKPGMSREDLFDKNVEIIADVSKNIKKYSPDSIIVVVSNPAD---- 129
Query: 531 IASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGE 632
I + L+K DP R++G+ +LD R TF+ +
Sbjct: 130 IMAYALQKISGVDPQRIMGLGGSLDSSRFRTFLAK 164
>UniRef50_Q8TWG5 Cluster: Malate dehydrogenase; n=2;
Euryarchaeota|Rep: Malate dehydrogenase - Methanopyrus
kandleri
Length = 317
Score = 72.9 bits (171), Expect = 6e-12
Identities = 40/93 (43%), Positives = 60/93 (64%), Gaps = 1/93 (1%)
Frame = +3
Query: 357 DADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIA 536
DADV+V+ AG+PRKPG TR DL NA+I++ +A+ P+AIV ++TNPV+ +A
Sbjct: 73 DADVIVMTAGIPRKPGQTRLDLTKDNAAIIKKYLEGVAEENPEAIVLVVTNPVDVLTYVA 132
Query: 537 SEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGE 632
LK +G+ NRV+G+ T LD +R + +
Sbjct: 133 ---LKVSGL-PKNRVIGLGTHLDSMRFKVLIAK 161
>UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=1;
Entamoeba histolytica|Rep: NAD-specific malate
dehydrogenase 2 - Entamoeba histolytica
Length = 329
Score = 72.5 bits (170), Expect = 9e-12
Identities = 47/143 (32%), Positives = 72/143 (50%), Gaps = 2/143 (1%)
Frame = +3
Query: 237 LALYDIAPVT-PGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTR 413
L LYD+ + G++ +L+ P K+ G E++ A + DV +I AGVPRKPGM R
Sbjct: 47 LHLYDLNDMALKGLSMELTDCCLP-KLKGIISTTEIALAFSNVDVAIIVAGVPRKPGMQR 105
Query: 414 DDLFNTNASIVRDIALSIAQNAPKAI-VAIITNPVNSTVPIASEVLKKAGVYDPNRVLGV 590
DL N N ++ ++ + K + V ++ NP N+ A + K +G+ P + +
Sbjct: 106 SDLINVNKKVMEMNGKALGTYSNKDVRVVVVANPANTN---AYVICKTSGI-PPEHITAL 161
Query: 591 TTLDVVRAATFVGEINGVDPTSV 659
T LD RA FV G P V
Sbjct: 162 TRLDQNRATAFVANEVGCQPEFV 184
>UniRef50_Q7M9A7 Cluster: Malate dehydrogenase; n=4;
Epsilonproteobacteria|Rep: Malate dehydrogenase -
Wolinella succinogenes
Length = 314
Score = 72.5 bits (170), Expect = 9e-12
Identities = 44/151 (29%), Positives = 81/151 (53%), Gaps = 2/151 (1%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHMNTPAKVSGHKGPEELSAAIKDA 362
+G +A +L + + + D+ T G+A D+ H + K + ++
Sbjct: 9 VGSTVAFILATQGICQEIIIKDLNLDTARGIALDMGHAASATKTHTIVRVANEPSDLRGC 68
Query: 363 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 542
DVVV AG PR+PGM+RDDL NA ++R + + ++++ +++NP+++ V A
Sbjct: 69 DVVVFCAGSPRQPGMSRDDLLLANAKVIRTVLSEVKPYIQESVLVMVSNPLDAMVYTA-- 126
Query: 543 VLKKAGVYDPNRVLGVT-TLDVVRAATFVGE 632
+K++G+ P +VLG+ LD R A+F+ E
Sbjct: 127 -IKESGL-SPLQVLGMAGILDSARMASFIFE 155
>UniRef50_A7I2F1 Cluster: Malate dehydrogenase; n=1; Campylobacter
hominis ATCC BAA-381|Rep: Malate dehydrogenase -
Campylobacter hominis (strain ATCC BAA-381 / LMG 19568 /
NCTC 13146 /CH001A)
Length = 297
Score = 70.5 bits (165), Expect = 3e-11
Identities = 49/150 (32%), Positives = 82/150 (54%), Gaps = 6/150 (4%)
Frame = +3
Query: 228 VTRLALYDI-APVTPGVAADLSHM----NTPAKVSGHKGPEELSAAIKDADVVVIPAGVP 392
++++AL DI + A DLSH+ N ++SG E L +K++D+VVI AG
Sbjct: 26 ISQIALIDIFGDLAKARALDLSHLASVYNKKTEISG-SSDETL---LKNSDIVVITAGKT 81
Query: 393 RKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDP 572
R+ G +R DL N NA I+ A ++A+ AP+AI+ +ITNPV++ +A KA +
Sbjct: 82 RQAGQSRADLLNDNAKIISSCAKNVAKYAPEAIIILITNPVDTLAFVA----YKASGFKK 137
Query: 573 NRVLGVT-TLDVVRAATFVGEINGVDPTSV 659
+++ + LD R + + V+ T +
Sbjct: 138 EKIIAMAGELDSARLRYEIAKSENVNVTDI 167
>UniRef50_Q81K80 Cluster: L-lactate dehydrogenase 2; n=12;
Firmicutes|Rep: L-lactate dehydrogenase 2 - Bacillus
anthracis
Length = 314
Score = 70.5 bits (165), Expect = 3e-11
Identities = 53/131 (40%), Positives = 64/131 (48%), Gaps = 1/131 (0%)
Frame = +3
Query: 270 GVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVR 449
G A DLSH P S K A KDAD+VVI AG+P+KPG TR DL N I +
Sbjct: 45 GEAMDLSHA-VPFSPSPTKVWSGSYADCKDADLVVITAGLPQKPGETRLDLVEKNTKIFK 103
Query: 450 DIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFV 626
I I + I I TNPV+ I + V K RV+G TTLD R +
Sbjct: 104 QIVRGIMDSGFDGIFLIATNPVD----ILTYVTWKESGLPKERVIGSGTTLDSARFRYML 159
Query: 627 GEINGVDPTSV 659
G+ VDP +V
Sbjct: 160 GDYLDVDPRNV 170
>UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter
hepaticus|Rep: Malate dehydrogenase - Helicobacter
hepaticus
Length = 315
Score = 69.7 bits (163), Expect = 6e-11
Identities = 46/149 (30%), Positives = 84/149 (56%), Gaps = 7/149 (4%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALY--DIAPVTPGVAADLSH----MNTPAKVSGHKGPEELSA 347
+G +A L + + L+ DI P GV D+S + P + G EE++
Sbjct: 14 VGSHIAFLGAMRHIAKEILLFSNDI-PRCKGVGLDISQAAAIFDIPILIKGCNSYEEIA- 71
Query: 348 AIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTV 527
+++VV+I AG PR P MTR+DL NASI+++I+ ++A+ AP++++ +++NP+++
Sbjct: 72 ---ESEVVIITAGFPRTPNMTRNDLLLKNASIIQEISSNVARIAPQSLLIVVSNPLDAMC 128
Query: 528 PIASEVLKKAGVYDPNRVLGVT-TLDVVR 611
+A + K ++ RV+G+ LD R
Sbjct: 129 LVAKQWSK----FEKERVIGMAGILDSAR 153
>UniRef50_Q3ZZJ7 Cluster: Malate dehydrogenase; n=5; cellular
organisms|Rep: Malate dehydrogenase - Dehalococcoides
sp. (strain CBDB1)
Length = 307
Score = 69.3 bits (162), Expect = 8e-11
Identities = 52/163 (31%), Positives = 87/163 (53%), Gaps = 4/163 (2%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELS---AAIK 356
+G LA L + + L + + G A D+S A V G + S A
Sbjct: 12 VGATLAQRLIEKDFADVVMLDVVEGIPQGKALDISQS---ASVLGFRHTITGSNDYAQTA 68
Query: 357 DADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIA 536
+++VVI AG+ RKPGMTR++L N I+ D+ + + +P+A + +++NPV++ +A
Sbjct: 69 GSEIVVITAGIARKPGMTREELLAINQKIMTDVVSNCLKYSPEATLVVVSNPVDTMTYLA 128
Query: 537 SEVLKKAGVYDPNRVLGVT-TLDVVRAATFVGEINGVDPTSVA 662
K +G+ RV+G++ LD R ATFV GV+P++V+
Sbjct: 129 ---WKLSGL-PRKRVVGLSGVLDGGRLATFVARELGVNPSAVS 167
>UniRef50_Q7UY63 Cluster: L-lactate/malate dehydrogenase; n=2;
Planctomycetaceae|Rep: L-lactate/malate dehydrogenase -
Rhodopirellula baltica
Length = 304
Score = 68.9 bits (161), Expect = 1e-10
Identities = 49/145 (33%), Positives = 79/145 (54%), Gaps = 3/145 (2%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIA-PVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 362
+G +A L NPL + L L + + G A DL+H + E++ + KD+
Sbjct: 11 VGSAIAFALTINPLASELLLLNRSREKAEGDALDLTHAAALVDSNIKISSGEIADS-KDS 69
Query: 363 DVVVIPAGVP-RKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 539
DV++ A VP R P TR ++ N I+RD +A+ +P AIV +++NPV++ +A
Sbjct: 70 DVIIFTASVPFRYPNQTRLEMGIDNMPILRDWMPGLAKASPNAIVVMVSNPVDA---LAY 126
Query: 540 EVLKKAGVYDPNRVLGVTTL-DVVR 611
E ++ G +DP RV+G TL D +R
Sbjct: 127 ETIRLTG-FDPKRVIGTGTLVDSIR 150
>UniRef50_Q1FID3 Cluster: L-lactate dehydrogenase precursor; n=1;
Clostridium phytofermentans ISDg|Rep: L-lactate
dehydrogenase precursor - Clostridium phytofermentans
ISDg
Length = 325
Score = 68.9 bits (161), Expect = 1e-10
Identities = 42/103 (40%), Positives = 59/103 (57%), Gaps = 1/103 (0%)
Frame = +3
Query: 354 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 533
KDAD+VVI AG P KPG +R D +A IV I + ++ I ++TNPV+S I
Sbjct: 74 KDADIVVITAGPPPKPGQSRLDTLGLSADIVSTIVEPVMKSGFNGIFLVVTNPVDS---I 130
Query: 534 ASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
A V + +G+ +VLG T +D R F+G+I VDP S+
Sbjct: 131 AQYVYQLSGL-PKQQVLGTGTAIDSARLKHFIGDILHVDPRSI 172
>UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 312
Score = 68.5 bits (160), Expect = 1e-10
Identities = 40/103 (38%), Positives = 58/103 (56%), Gaps = 1/103 (0%)
Frame = +3
Query: 354 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 533
KDAD++VI AGVPR PG TR D+ + + VRDI ++ + K I+ ITNP + I
Sbjct: 71 KDADIIVISAGVPRLPGQTRLDVLDGSVECVRDIVSNLNKIEIKGIIITITNPAD----I 126
Query: 534 ASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
++ ++KA NRV T+LD R V ++ + P SV
Sbjct: 127 IADFVRKATGLPKNRVFSTGTSLDTARMRRTVADLCNIAPQSV 169
>UniRef50_Q892U0 Cluster: L-lactate dehydrogenase; n=12;
Bacteria|Rep: L-lactate dehydrogenase - Clostridium
tetani
Length = 316
Score = 68.5 bits (160), Expect = 1e-10
Identities = 54/161 (33%), Positives = 79/161 (49%), Gaps = 3/161 (1%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHMNTPAK-VSGHKGPEELSAAIKD 359
+G A L L + + + DI G A DLSH + K V G E + KD
Sbjct: 16 VGSTTAYALMMEGLASEIVIVDINKEKAKGEAMDLSHGVSFVKPVDIIAGDYEDT---KD 72
Query: 360 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 539
+D+V+I AG KPG TR DL N N I + I + + +PK+I+ +++NPV+ I +
Sbjct: 73 SDIVIITAGAGPKPGETRLDLINKNYEIFKGIVPEVVKYSPKSILLVVSNPVD----ILT 128
Query: 540 EVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
V K + RV+G T LD R +GE +D +V
Sbjct: 129 YVTYKLSGFPQERVIGSGTVLDTSRFRYLLGEHFKIDVRNV 169
>UniRef50_Q7NHJ3 Cluster: Malate dehydrogenase; n=13; cellular
organisms|Rep: Malate dehydrogenase - Gloeobacter
violaceus
Length = 325
Score = 68.1 bits (159), Expect = 2e-10
Identities = 53/153 (34%), Positives = 76/153 (49%), Gaps = 6/153 (3%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHMNTPAKVSGHK----GPEELSAA 350
+G LA L Q V + L DI P G+ DL V GH G + A
Sbjct: 19 VGSALAQRLIQGN-VADVVLLDIVEGRPQGITLDLLEA---CGVEGHTCRITGTNDY-AQ 73
Query: 351 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 530
+DV+V+ AG R+PGM+RDDL TN IV ++ ++P+A V ++TNP+++
Sbjct: 74 TAGSDVLVVAAGFARQPGMSRDDLLLTNTRIVFEVTQKAVAHSPEATVVVVTNPLDA--- 130
Query: 531 IASEVLKKAGVYDPNRVLGVT-TLDVVRAATFV 626
S V +A P RV+G+ LD R TF+
Sbjct: 131 -MSHVAWRASGLVPERVMGMAGVLDAARFETFI 162
>UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex
aeolicus|Rep: Malate dehydrogenase 2 - Aquifex aeolicus
Length = 334
Score = 68.1 bits (159), Expect = 2e-10
Identities = 39/123 (31%), Positives = 67/123 (54%), Gaps = 1/123 (0%)
Frame = +3
Query: 294 MNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQ 473
M+ V G +E +K +D+VVI AG+PR+ GM+R+DL N I++ +I +
Sbjct: 67 MDIDINVKGISYDKEGFEELKGSDIVVITAGIPRREGMSREDLLYENLKILKKFTDAIKE 126
Query: 474 NAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVT-TLDVVRAATFVGEINGVDP 650
A +I+ +++NPV++ + +K G ++P RV+G+ LD R FV E G+
Sbjct: 127 YAKDSIIIVVSNPVDT---LTYATIKLTG-FEPRRVIGMAGVLDSARFKNFVKEKIGISN 182
Query: 651 TSV 659
+
Sbjct: 183 ADI 185
>UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2;
Ascomycota|Rep: Probable L-lactate dehydrogenase -
Schizosaccharomyces pombe (Fission yeast)
Length = 330
Score = 68.1 bits (159), Expect = 2e-10
Identities = 61/189 (32%), Positives = 86/189 (45%), Gaps = 8/189 (4%)
Frame = +3
Query: 117 GAKNFSTTSQRN--FKXXXXXXXXX--IGQPLALLLKQNPLVTRLALYDI-APVTPGVAA 281
G+K FS S R+ FK +G A L + L + + D+ G A
Sbjct: 4 GSKVFSNDSVRSSSFKSIKIVIVGAGNVGSTTAFTLLLSGLAAEIVIIDLNKKKAEGEAM 63
Query: 282 DLSHMNTPAKVSGHKGPEELS--AAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDI 455
DL+H A H+ L KDA VVI AG +KPG TR DL N SI ++I
Sbjct: 64 DLNH----AAPLSHETRVYLGDYKDCKDATAVVITAGKNQKPGETRMDLLKANISIFKEI 119
Query: 456 ALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGE 632
+ + AI+ + TNPV+ + LK G + RV+G T +D R +G+
Sbjct: 120 LREVTKYTKDAILLVATNPVD---VLTYATLKLTG-FPAERVIGSGTIIDTARFQYLIGK 175
Query: 633 INGVDPTSV 659
+ G+DP SV
Sbjct: 176 LYGLDPQSV 184
>UniRef50_A5KJY5 Cluster: Putative uncharacterized protein; n=2;
Ruminococcus|Rep: Putative uncharacterized protein -
Ruminococcus torques ATCC 27756
Length = 316
Score = 67.3 bits (157), Expect = 3e-10
Identities = 54/161 (33%), Positives = 78/161 (48%), Gaps = 3/161 (1%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAPV-TPGVAADLSH-MNTPAKVSGHKGPEELSAAIKD 359
+G +A L Q L + + L D G A D+SH + + + G E I D
Sbjct: 15 VGSTIAYTLMQKGLFSEMVLLDANKAKAEGEAMDISHGLPFTHAMDIYAGEYE---DIAD 71
Query: 360 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 539
A VV+I AG +KPG TR DL NA+I+R I I + + I+ I++NPV+ I +
Sbjct: 72 ASVVIITAGANQKPGETRLDLVQKNAAIMRSIIKEIKRVNCEGILLIVSNPVD----ILT 127
Query: 540 EVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
EV + + RV+G T LD R + E VD +V
Sbjct: 128 EVALRESGFPKERVIGSGTVLDTARLKYIISEKLDVDSRNV 168
>UniRef50_A3EWH3 Cluster: Malate/lactate dehydrogenase; n=1;
Leptospirillum sp. Group II UBA|Rep: Malate/lactate
dehydrogenase - Leptospirillum sp. Group II UBA
Length = 320
Score = 67.3 bits (157), Expect = 3e-10
Identities = 36/104 (34%), Positives = 63/104 (60%), Gaps = 1/104 (0%)
Frame = +3
Query: 351 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 530
I+ + VVV+ AG RKPGM+R+DL + N I+ ++A I ++AP ++V ++TNP++
Sbjct: 72 IEGSSVVVVTAGFSRKPGMSREDLLHKNGDIMIEVAEKIRKHAPDSVVIMVTNPMD---- 127
Query: 531 IASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
+ + +L K + RV+G+ LD R A FV E+ +++
Sbjct: 128 LMAYILWKVTGFPRERVIGMGGALDSSRFAYFVSEVTNTSVSNI 171
>UniRef50_A4L2P0 Cluster: L-lactate dehydrogenase; n=4;
Lactobacillus|Rep: L-lactate dehydrogenase -
Lactobacillus reuteri
Length = 312
Score = 66.5 bits (155), Expect = 6e-10
Identities = 44/112 (39%), Positives = 65/112 (58%), Gaps = 1/112 (0%)
Frame = +3
Query: 279 ADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIA 458
AD++ + P K+ + G E +A DADVVVI AG+PRKPG TR DL N N +I++ I
Sbjct: 53 ADITPLTNPVKI--YAGTYEDAA---DADVVVITAGIPRKPGETRLDLVNKNTTILKSII 107
Query: 459 LSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGV-TTLDVVR 611
I ++ + I +NPV+ IA + +G + RV+G T+LD +R
Sbjct: 108 KPIVKSGFTGVFVISSNPVDILTTIAQRI---SG-FPKERVIGTGTSLDSMR 155
>UniRef50_Q18WQ6 Cluster: Malate dehydrogenase, NAD-dependent; n=2;
Desulfitobacterium hafniense|Rep: Malate dehydrogenase,
NAD-dependent - Desulfitobacterium hafniense (strain
DCB-2)
Length = 320
Score = 66.1 bits (154), Expect = 7e-10
Identities = 36/91 (39%), Positives = 58/91 (63%), Gaps = 1/91 (1%)
Frame = +3
Query: 357 DADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIA 536
D+DVVVI AG+ RKPGM+R++L + NA IV + + Q++P + + I++NPV+ +A
Sbjct: 71 DSDVVVITAGIARKPGMSRNELCDINAGIVTHVVRQVVQHSPNSTLIILSNPVDIMTYVA 130
Query: 537 SEVLKKAGVYDPNRVLGVT-TLDVVRAATFV 626
K++G + NR++G + LD R FV
Sbjct: 131 ---FKESG-FKRNRIIGQSGVLDSARFRYFV 157
>UniRef50_P19869 Cluster: L-lactate dehydrogenase 2; n=17;
Bacteria|Rep: L-lactate dehydrogenase 2 -
Bifidobacterium longum
Length = 320
Score = 66.1 bits (154), Expect = 7e-10
Identities = 50/163 (30%), Positives = 78/163 (47%), Gaps = 5/163 (3%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAPV-TPGVAADLSHMNT---PAKVSGHKGPEELSAAI 353
+G LA Q + + L DIA D+ H ++ + G PE
Sbjct: 19 VGSTLAFAAAQRGIAREIVLEDIAKERVEAEVLDMQHGSSFYPTVSIDGSDDPE----IC 74
Query: 354 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 533
+DAD+VVI AG +KPG +R +L +I++ I ++ + AP AI +ITNPV+ I
Sbjct: 75 RDADMVVITAGPRQKPGQSRLELVGATVNILKAIMPNLVKVAPNAIYMLITNPVD----I 130
Query: 534 ASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
A+ V +K N++ G T LD R + + GV+ +V
Sbjct: 131 ATHVAQKLTGLPENQIFGSGTNLDSARLRFLIAQQTGVNVKNV 173
>UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3;
Methanomicrobiales|Rep: L-lactate dehydrogenase -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 319
Score = 65.7 bits (153), Expect = 1e-09
Identities = 53/166 (31%), Positives = 86/166 (51%), Gaps = 8/166 (4%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIA---PVTPGVAADL----SHMNTPAKVSGHKGPEELS 344
+G +A + Q P V + LY G+A D+ + T +V+ P+EL
Sbjct: 13 VGSYVAHAVSQFPHVQEMCLYGRPGNEQYLDGLAHDMMDSFAARGTNTRVTFGTTPKEL- 71
Query: 345 AAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNST 524
+ +D++V+ +GVPRK TR DL NA IV+ A + + AP+AI+ ++TNPV+
Sbjct: 72 ---RGSDIIVLTSGVPRKATQTRLDLALENARIVKVFAEQVGRMAPEAILLVVTNPVDIM 128
Query: 525 VPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
+A LK +G+ P+RV G+ T LD +R + E V + +
Sbjct: 129 TTVA---LKYSGMM-PHRVFGLGTHLDSMRLKACLAEFFNVHVSEI 170
>UniRef50_Q6A9C3 Cluster: L-lactate dehydrogenase; n=2;
Propionibacterium acnes|Rep: L-lactate dehydrogenase -
Propionibacterium acnes
Length = 319
Score = 65.7 bits (153), Expect = 1e-09
Identities = 51/145 (35%), Positives = 71/145 (48%), Gaps = 4/145 (2%)
Frame = +3
Query: 237 LALYDIAP-VTPGVAADLSHMN--TPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGM 407
++LYDIA ADL+H TPA V G G + A D+DVV I AG +KPG
Sbjct: 38 VSLYDIAKDKVEAEVADLAHGTQFTPASVMG--GADVHDTA--DSDVVFITAGARQKPGQ 93
Query: 408 TRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLG 587
TR DL NA+I+R + + + +P A+ ++TNP + +A E A NRV
Sbjct: 94 TRLDLAGVNANILRSLMPQLVEQSPNALFVLVTNPCDVLTVVAQE----ATGLPANRVFS 149
Query: 588 V-TTLDVVRAATFVGEINGVDPTSV 659
T LD R + + V+ V
Sbjct: 150 TGTMLDTSRLRWLIRQWANVEQRHV 174
>UniRef50_Q2S4R2 Cluster: L-lactate dehydrogenase; n=1; Salinibacter
ruber DSM 13855|Rep: L-lactate dehydrogenase -
Salinibacter ruber (strain DSM 13855)
Length = 316
Score = 65.3 bits (152), Expect = 1e-09
Identities = 41/108 (37%), Positives = 60/108 (55%), Gaps = 3/108 (2%)
Frame = +3
Query: 345 AAIKDADVVVIPAGVPRK-PGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNS 521
AA+ +A ++V+ AG ++ P TR L NA I R+I + + ++AP AI+ + TNPV+
Sbjct: 67 AALSNAQIIVLSAGASQQSPDETRLGLLQRNAEIFREIIIQLDKHAPNAILVVATNPVDV 126
Query: 522 TVPIASEVLKKAGVYDPN-RVLGV-TTLDVVRAATFVGEINGVDPTSV 659
I E+ + PN R+LG T LD R +G GVDP SV
Sbjct: 127 LTYICQELSSR-----PNRRILGTGTLLDTARFRALLGRHYGVDPRSV 169
>UniRef50_Q27743 Cluster: L-lactate dehydrogenase; n=17;
Apicomplexa|Rep: L-lactate dehydrogenase - Plasmodium
falciparum (isolate CDC / Honduras)
Length = 316
Score = 64.9 bits (151), Expect = 2e-09
Identities = 56/169 (33%), Positives = 84/169 (49%), Gaps = 11/169 (6%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHMNTPA----KVSGHKGPEELSAA 350
IG +A L+ Q L + L+DI P G A D SH N A KVSG ++L+ A
Sbjct: 15 IGGVMATLIVQKNLGD-VVLFDIVKNMPHGKALDTSHTNVMAYSNCKVSGSNTYDDLAGA 73
Query: 351 IKDADVVVIPAGVPRKPGMT-----RDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPV 515
DVV++ AG + PG + RDDL N I+ +I I +N P A + ++TNPV
Sbjct: 74 ----DVVIVTAGFTKAPGKSDKEWNRDDLLPLNNKIMIEIGGHIKKNCPNAFIIVVTNPV 129
Query: 516 NSTVPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
+ V + + +GV N+++G+ LD R ++ + V P V
Sbjct: 130 DVMVQLLHQ---HSGV-PKNKIIGLGGVLDTSRLKYYISQKLNVCPRDV 174
>UniRef50_Q8XP62 Cluster: L-lactate dehydrogenase; n=11;
Clostridium|Rep: L-lactate dehydrogenase - Clostridium
perfringens
Length = 317
Score = 64.9 bits (151), Expect = 2e-09
Identities = 48/160 (30%), Positives = 76/160 (47%), Gaps = 2/160 (1%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 362
+G A L Q+ L + + + DI A DL+ K K + A KD+
Sbjct: 17 VGSTTAFALMQDGLASEIVIVDINKDKAHAEAMDLAQGAAFVKSVDIKSGDY--ADTKDS 74
Query: 363 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 542
D+V+I AGV KPG TR D+ N N I + I + + +P +I+ +++NPV+ I +
Sbjct: 75 DIVIITAGVGPKPGETRLDIINKNLKIFQSIVPEVVKYSPNSILLVVSNPVD----ILTY 130
Query: 543 VLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
+ K + RV+G T LD R + E +D +V
Sbjct: 131 ITYKLSGFPKERVIGSGTVLDTSRLKYMLSEHFDIDARNV 170
>UniRef50_P59390 Cluster: L-lactate dehydrogenase 2; n=8;
Lactobacillus|Rep: L-lactate dehydrogenase 2 -
Lactobacillus plantarum
Length = 309
Score = 64.5 bits (150), Expect = 2e-09
Identities = 48/160 (30%), Positives = 73/160 (45%), Gaps = 2/160 (1%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAPV-TPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 362
+G A L QN + L + D+ G DL + + E A +DA
Sbjct: 16 VGSSFAFSLVQNCALDELVIVDLVKTHAEGDVKDLEDVAAFTNATNIHTGEYADA--RDA 73
Query: 363 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 542
D+VVI AGVPRKPG +R DL N N I+ I + + I +NPV+ I +
Sbjct: 74 DIVVITAGVPRKPGESRLDLINRNTKILESIVKPVVASGFNGCFVISSNPVD----ILTS 129
Query: 543 VLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
+ ++ + +RV+G T+LD R + + V T+V
Sbjct: 130 MTQRLSGFPRHRVIGTGTSLDTARLRVALAQKLNVATTAV 169
>UniRef50_A4BB89 Cluster: Lactate dehydrogenase; n=2;
Gammaproteobacteria|Rep: Lactate dehydrogenase -
Reinekea sp. MED297
Length = 319
Score = 64.1 bits (149), Expect = 3e-09
Identities = 40/105 (38%), Positives = 56/105 (53%), Gaps = 1/105 (0%)
Frame = +3
Query: 351 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 530
+ DAD+VVI AG K G TRDDL N+ I DIA I AP AI+ ++TNP +
Sbjct: 68 LTDADIVVITAGAQIKEGQTRDDLAEINSRITVDIAQKIETVAPNAILLVVTNPCD---- 123
Query: 531 IASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSVA 662
IA+ + + + +RV+ +D R V E VDP +V+
Sbjct: 124 IATYFITQNTGFPADRVISAGCIIDTARLMKLVSEKVDVDPKNVS 168
>UniRef50_A0RPE9 Cluster: Malate dehydrogenase; n=1; Campylobacter
fetus subsp. fetus 82-40|Rep: Malate dehydrogenase -
Campylobacter fetus subsp. fetus (strain 82-40)
Length = 306
Score = 64.1 bits (149), Expect = 3e-09
Identities = 47/156 (30%), Positives = 81/156 (51%), Gaps = 2/156 (1%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 362
+G A LL + ++ L DI + A DL+ M + + +KD
Sbjct: 11 VGASCASLLISRKVCKKVTLIDINKNLAIAKAMDLAQMAAVLNLDIDIFGGDNYELLKDF 70
Query: 363 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 542
D+VVI AG RK G +RDDL NA IV + +++ APK+I+ ++TNP++ V +A
Sbjct: 71 DIVVITAGFARKDGQSRDDLAMMNAKIVSHSSKMVSKFAPKSIIIVVTNPLDIMVYVA-- 128
Query: 543 VLKKAGVYDPNRVLGVT-TLDVVRAATFVGEINGVD 647
K++G + ++V+G+ LD R ++ + G++
Sbjct: 129 -FKESG-FARHKVIGMAGELDSARFRYYMSQKLGLN 162
>UniRef50_P11386 Cluster: Malate dehydrogenase; n=6;
Sulfolobaceae|Rep: Malate dehydrogenase - Sulfolobus
acidocaldarius
Length = 306
Score = 64.1 bits (149), Expect = 3e-09
Identities = 42/126 (33%), Positives = 62/126 (49%), Gaps = 1/126 (0%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAPVTPG-VAADLSHMNTPAKVSGHKGPEELSAAIKDA 362
+GQ +A N + LYD+ P P ++ H +V I A
Sbjct: 12 VGQTIAYNTIVNGYADEVMLYDVVPELPEKFEHEIRHALAALRVKTELLSTNNIDDISGA 71
Query: 363 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 542
D+VVI AG PRKPGM+R DLF NA I+ D+A + + A+ ++ NPV+ +AS
Sbjct: 72 DIVVITAGKPRKPGMSRRDLFIDNAKIMIDLAKKLPKKNKGAMYIMVANPVDM---MASV 128
Query: 543 VLKKAG 560
+K +G
Sbjct: 129 FMKYSG 134
>UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasma
hyopneumoniae|Rep: L-lactate dehydrogenase - Mycoplasma
hyopneumoniae
Length = 315
Score = 64.1 bits (149), Expect = 3e-09
Identities = 38/104 (36%), Positives = 56/104 (53%), Gaps = 1/104 (0%)
Frame = +3
Query: 351 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 530
+KDAD +VI AG P+KPG TR +L N I+R+IAL + ++ I I+ NPV+
Sbjct: 69 LKDADFIVITAGRPQKPGETRLELVADNIRIIREIALKVKESGFSGISIIVANPVD---- 124
Query: 531 IASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
I + + A + +V+G T LD R + + V P SV
Sbjct: 125 IITRAYRDASGFSDQKVIGSGTVLDTARLQFAIAKRAKVSPNSV 168
>UniRef50_O26290 Cluster: Malate dehydrogenase; n=2;
Methanobacteriaceae|Rep: Malate dehydrogenase -
Methanobacterium thermoautotrophicum
Length = 325
Score = 63.7 bits (148), Expect = 4e-09
Identities = 50/151 (33%), Positives = 75/151 (49%), Gaps = 4/151 (2%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKD-- 359
+G+ AL L + V L L ++ M+ G E SA I++
Sbjct: 12 VGRATALCLAEEEAVKTLHLISRKESLEQNLGEVLDMSDALAAKGVSVKLENSADIENVY 71
Query: 360 -ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIA 536
+ +VVI AGVPR M RDDL N IV D A IA+ AP +I+ ++TNPV+ +A
Sbjct: 72 GSRIVVITAGVPRTADMDRDDLAFKNGRIVADYARQIARFAPDSIILVVTNPVDVMTYVA 131
Query: 537 SEVLKKAGVYDPNRVLGV-TTLDVVRAATFV 626
L+ +G + P+RV G+ LD +R ++
Sbjct: 132 ---LRYSG-FHPSRVFGLGNHLDSLRLKNYM 158
>UniRef50_P62056 Cluster: L-lactate dehydrogenase; n=2;
Bacteria|Rep: L-lactate dehydrogenase - Treponema
denticola
Length = 315
Score = 63.3 bits (147), Expect = 5e-09
Identities = 50/161 (31%), Positives = 79/161 (49%), Gaps = 3/161 (1%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSH-MNTPAKVSGHKGPEELSAAIKD 359
+G A L Q+ +A+ D+ G A DL + +V H G + A D
Sbjct: 16 VGSTFAYALAQSGYADEIAITDMNKNFAEGQALDLVQGLPFLPQVDIHAGDKTDYA---D 72
Query: 360 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 539
+D+VV+ AG ++ G TR DL NASI+ IA IA++ ++ I++NPV+ I +
Sbjct: 73 SDIVVVTAGAKQQSGETRIDLLKRNASIITGIAKDIAESGCSGVMLIVSNPVD----ILT 128
Query: 540 EVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
KA ++ RV+G T LD R + + GVD ++
Sbjct: 129 RAALKASGWERGRVIGSGTVLDTARFRYTLSKECGVDARNI 169
>UniRef50_Q81XJ7 Cluster: L-lactate dehydrogenase 3; n=13;
Firmicutes|Rep: L-lactate dehydrogenase 3 - Bacillus
anthracis
Length = 316
Score = 61.7 bits (143), Expect = 2e-08
Identities = 54/164 (32%), Positives = 78/164 (47%), Gaps = 6/164 (3%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHM----NTPAKVSGHKGPEELSAA 350
+G A + + L L DI G A DLSH NT KV + G E
Sbjct: 16 VGSSCAYSIVNQGICEELLLIDINHERAVGEAMDLSHCINFTNTRTKV--YAGSYE---D 70
Query: 351 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 530
KD D+V+I AG KPG +R D +A I+ + + ++ I + +NPV+
Sbjct: 71 CKDMDIVIITAGPAPKPGQSRLDTLGASAKIMESVVGGVMESGFDGIFLLASNPVDI--- 127
Query: 531 IASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
I +V K +G+ NRV+G T+LD R T + E+ VDP S+
Sbjct: 128 ITYQVWKLSGL-PRNRVIGTGTSLDSSRLRTILSEMLHVDPRSI 170
>UniRef50_Q6JH30 Cluster: Lactate dehydrogenase; n=3; Plasmodium
(Plasmodium)|Rep: Lactate dehydrogenase - Plasmodium
vivax
Length = 299
Score = 61.3 bits (142), Expect = 2e-08
Identities = 53/169 (31%), Positives = 83/169 (49%), Gaps = 11/169 (6%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHMNTPA----KVSGHKGPEELSAA 350
IG +A L+ Q L + ++D+ P G A D SH N A KV+G ++L
Sbjct: 8 IGGVMATLIVQKNLGD-VVMFDVVKNMPQGKALDTSHSNVMAYSNCKVTGSNSYDDL--- 63
Query: 351 IKDADVVVIPAGVPRKPGMT-----RDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPV 515
K ADVV++ AG + PG + RDDL N I+ +I I P A + ++TNPV
Sbjct: 64 -KGADVVIVTAGFTKAPGKSDKEWNRDDLLPLNNKIMIEIGGHIKNLCPNAFIIVVTNPV 122
Query: 516 NSTVPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
+ V + + + +GV N+++G+ LD R ++ + V P V
Sbjct: 123 DVMVQL---LFEHSGV-PKNKIIGLGGVLDTSRLKYYISQKLNVCPRDV 167
>UniRef50_Q6F0L9 Cluster: L-lactate dehydrogenase; n=6;
Mollicutes|Rep: L-lactate dehydrogenase - Mesoplasma
florum (Acholeplasma florum)
Length = 317
Score = 61.3 bits (142), Expect = 2e-08
Identities = 38/103 (36%), Positives = 57/103 (55%), Gaps = 1/103 (0%)
Frame = +3
Query: 354 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 533
KDAD++VI AG P++PG TR +L N+ I++ IA +I + + I +NP + +
Sbjct: 72 KDADLIVITAGRPQRPGETRLELIADNSRIMKGIAEAIKASGFNGVTVIASNPCD----V 127
Query: 534 ASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
+ V ++ YD + V+G TTLD R V E V P SV
Sbjct: 128 LTTVYQQVTGYDEHSVVGAGTTLDSARLRRLVAEKLNVAPKSV 170
>UniRef50_P0A3M9 Cluster: L-lactate dehydrogenase; n=140;
Bacteria|Rep: L-lactate dehydrogenase - Streptococcus
pneumoniae
Length = 328
Score = 60.9 bits (141), Expect = 3e-08
Identities = 55/178 (30%), Positives = 77/178 (43%), Gaps = 4/178 (2%)
Frame = +3
Query: 138 TSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPV---TPGVAADLSHMNTPA 308
TS + K +G A L + L + +I + G A DLSH A
Sbjct: 2 TSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLHEKAVGDALDLSH--ALA 59
Query: 309 KVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKA 488
S K + DAD+VVI AG P+KPG TR DL N +I + I + ++ K
Sbjct: 60 FTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNLAINKSIVTQVVESGFKG 119
Query: 489 IVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
I + NPV+ + K +G + RV+G T+LD R + E VD SV
Sbjct: 120 IFLVAANPVD---VLTYSTWKFSG-FPKERVIGSGTSLDSARFRQALAEKLDVDARSV 173
>UniRef50_Q98PG4 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
pulmonis|Rep: L-lactate dehydrogenase - Mycoplasma
pulmonis
Length = 315
Score = 60.9 bits (141), Expect = 3e-08
Identities = 42/131 (32%), Positives = 65/131 (49%), Gaps = 1/131 (0%)
Frame = +3
Query: 270 GVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVR 449
G A D+S +G K A K AD++++ AG P+K G TR ++ N+ I++
Sbjct: 41 GHAMDMSDAIALNSTTGSKIRTGTYADAKGADLLIVAAGRPQKQGETRLEMIADNSKIMK 100
Query: 450 DIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFV 626
DIAL I ++ +I+NPV+ I + V +K + +V+ T LD R F+
Sbjct: 101 DIALEIKKSGFNGFTIVISNPVD----ILATVFQKVTNFPKEKVMSSGTFLDTSRFRKFL 156
Query: 627 GEINGVDPTSV 659
E GV SV
Sbjct: 157 SEKTGVPTNSV 167
>UniRef50_P62051 Cluster: L-lactate dehydrogenase; n=2;
Desulfovibrio vulgaris subsp. vulgaris|Rep: L-lactate
dehydrogenase - Desulfovibrio vulgaris (strain
Hildenborough / ATCC 29579 / NCIMB8303)
Length = 309
Score = 60.9 bits (141), Expect = 3e-08
Identities = 41/101 (40%), Positives = 52/101 (51%), Gaps = 1/101 (0%)
Frame = +3
Query: 360 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 539
A +VV+ AG + PG +R DL NA I RDI ++ Q A + + TNPV+ +A
Sbjct: 69 ARIVVVTAGAKQMPGQSRLDLVRVNAGITRDILTAVMQYADDPLYIMATNPVDVLTHVAR 128
Query: 540 EVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
V GV P RV+G T LD R V EI GVD V
Sbjct: 129 TV---TGV-APGRVIGSGTVLDSARFRGHVAEILGVDVRGV 165
>UniRef50_Q8I8U4 Cluster: Lactate dehydrogenase; n=3;
Eimeriorina|Rep: Lactate dehydrogenase - Eimeria tenella
Length = 331
Score = 60.5 bits (140), Expect = 4e-08
Identities = 48/148 (32%), Positives = 71/148 (47%), Gaps = 7/148 (4%)
Frame = +3
Query: 237 LALYDIAPVTP-GVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPG--- 404
+ L+D+ P P G A DL H A A+++ ADVV+I AG+ + G
Sbjct: 36 VVLFDVVPNMPAGKALDLCHTAAVADNGVRVQGANSYASLEGADVVIITAGITKAAGKSD 95
Query: 405 --MTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNR 578
+R DL N I+R++ +I Q P A V ITNP++ V +A+ L++A R
Sbjct: 96 QEWSRKDLLPVNVKILREVGAAIKQFCPHAFVINITNPLD--VMVAA--LREAAGLPAAR 151
Query: 579 VLGVT-TLDVVRAATFVGEINGVDPTSV 659
V G+ LD R + + GV P V
Sbjct: 152 VCGMAGVLDSARFRRLLADRLGVSPRDV 179
>UniRef50_A3DCA4 Cluster: L-lactate dehydrogenase precursor; n=2;
Clostridium|Rep: L-lactate dehydrogenase precursor -
Clostridium thermocellum (strain ATCC 27405 / DSM 1237)
Length = 318
Score = 60.1 bits (139), Expect = 5e-08
Identities = 45/161 (27%), Positives = 78/161 (48%), Gaps = 3/161 (1%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSH-MNTPAKVSGHKGPEELSAAIKD 359
+G A + L L D+ G A D++H + ++S + G + +KD
Sbjct: 18 VGASAAFTMALRQTANELVLIDVFKEKAIGEAMDINHGLPFMGQMSLYAGDY---SDVKD 74
Query: 360 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 539
DV+V+ AG RKPG TR DL N I +++ +I + ++ +++NPV+ I +
Sbjct: 75 CDVIVVTAGANRKPGETRLDLAKKNVMIAKEVTQNIMKYYNHGVILVVSNPVD----IIT 130
Query: 540 EVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
+++K +V+G T LD +R + E GVD +V
Sbjct: 131 YMIQKWSGLPVGKVIGSGTVLDSIRFRYLLSEKLGVDVKNV 171
>UniRef50_Q838C9 Cluster: L-lactate dehydrogenase 2; n=9;
Bacilli|Rep: L-lactate dehydrogenase 2 - Enterococcus
faecalis (Streptococcus faecalis)
Length = 317
Score = 59.7 bits (138), Expect = 6e-08
Identities = 37/103 (35%), Positives = 59/103 (57%), Gaps = 1/103 (0%)
Frame = +3
Query: 354 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 533
+DAD+VVI AG +KPG +R DL + NA I++ I +I ++ I+ I +NPV+ +
Sbjct: 72 QDADIVVITAGANQKPGQSRLDLVSINAEIMKTIVNNIMKSGFDGILVIASNPVD----V 127
Query: 534 ASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
+ V +A +RV+G TTLD R + + +DP +V
Sbjct: 128 LTYVAWQASGLPVSRVIGTGTTLDTTRFRKELSQRLAIDPRNV 170
>UniRef50_Q8ELF0 Cluster: L-lactate dehydrogenase; n=5;
Bacillaceae|Rep: L-lactate dehydrogenase -
Oceanobacillus iheyensis
Length = 321
Score = 59.3 bits (137), Expect = 9e-08
Identities = 52/176 (29%), Positives = 77/176 (43%), Gaps = 2/176 (1%)
Frame = +3
Query: 138 TSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHMNTPAKV 314
TSQ+ +G A L + LA+ D+ A G DL+H A
Sbjct: 3 TSQQAVNRVVLIGGGSVGVSYAFALMNQGVTEELAIIDLDADKALGDVMDLNHGKAFAPS 62
Query: 315 SGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIV 494
+ E KDAD+V I AG ++ G TR DL N I ++I + + I
Sbjct: 63 LTNVWLGEYGDC-KDADIVCICAGANQQSGETRLDLVEKNMKIFKEIVTDVMNSGFNGIF 121
Query: 495 AIITNPVNSTVPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
I TNPV+ + V+ +G+ P+RV+G TTLD R +GE + P ++
Sbjct: 122 LIATNPVDI---LTQAVISFSGL-PPHRVIGSGTTLDTARLRYELGEYFHLSPKNI 173
>UniRef50_Q6KIP9 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
mobile|Rep: L-lactate dehydrogenase - Mycoplasma mobile
Length = 318
Score = 59.3 bits (137), Expect = 9e-08
Identities = 37/104 (35%), Positives = 59/104 (56%), Gaps = 1/104 (0%)
Frame = +3
Query: 351 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 530
+KD DVVVI AG P+KPG TR ++ NA I+ +IA +I ++ K + ++ NPV+
Sbjct: 71 LKDYDVVVITAGRPQKPGETRLEMVADNAKIMSNIAKNIKKSGFKGVSIVVANPVD---- 126
Query: 531 IASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
+ + + + +D NRV+ T+LD R + + V P SV
Sbjct: 127 VMTFIYQHETGFDKNRVISSGTSLDSARLRFEISKKLKVHPKSV 170
>UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;
Candidatus Methanoregula boonei 6A8|Rep: L-lactate
dehydrogenase precursor - Methanoregula boonei (strain
6A8)
Length = 332
Score = 58.4 bits (135), Expect = 1e-07
Identities = 36/93 (38%), Positives = 54/93 (58%), Gaps = 1/93 (1%)
Frame = +3
Query: 351 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 530
+ +D+VVI AG PR PG R DL NA I+ +A +I AP + ++TNPV+
Sbjct: 71 VAGSDIVVITAGTPRGPGQNRLDLALGNARIIAPMARTIGTIAPDTKIIMVTNPVDVMTC 130
Query: 531 IASEVLKKAGVYDPNRVLGV-TTLDVVRAATFV 626
+A LK +G+ PN+V G+ T LD +R + +
Sbjct: 131 VA---LKYSGL-KPNQVFGLGTHLDSMRLKSLI 159
>UniRef50_A6M0Q2 Cluster: L-lactate dehydrogenase; n=1; Clostridium
beijerinckii NCIMB 8052|Rep: L-lactate dehydrogenase -
Clostridium beijerinckii NCIMB 8052
Length = 316
Score = 58.0 bits (134), Expect = 2e-07
Identities = 49/162 (30%), Positives = 75/162 (46%), Gaps = 4/162 (2%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAPVTPGV-AADLSHM--NTPAKVSGHKGPEELSAAIK 356
+G +A + N + L L DI A DL H + +K+ G E
Sbjct: 16 VGAAVAFDMVMNHVCDDLILIDINKEKSWAEATDLQHSLGYSGSKMRVKDGEYE---ECN 72
Query: 357 DADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIA 536
DAD+VVI A +P G TR D+ A I+ +I +I ++ I+ +ITNPV+ +
Sbjct: 73 DADIVVIAAALPYITGQTRLDMLEKAAGIMNNIVPNIMKSGFSGIIVVITNPVD----VM 128
Query: 537 SEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
S + K ++V+G T LD R + ++ VDP SV
Sbjct: 129 SYYVHKLSGLPASKVIGTGTALDSARLKYHLADVMSVDPQSV 170
>UniRef50_Q9P4B6 Cluster: L-lactate dehydrogenase A; n=48; Rhizopus
oryzae|Rep: L-lactate dehydrogenase A - Rhizopus oryzae
(Rhizopus delemar)
Length = 320
Score = 58.0 bits (134), Expect = 2e-07
Identities = 42/160 (26%), Positives = 72/160 (45%), Gaps = 2/160 (1%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 362
+G A L + T + + D+ P + DL+ + + G E + A
Sbjct: 15 VGASTAYALMFKNICTEIIIVDVNPDIVQAQVLDLADAASISHTPIRAGSAEEAG---QA 71
Query: 363 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 542
D+VVI AG ++ G R L N +++ I + P A++ ++ NPV+ I +
Sbjct: 72 DIVVITAGAKQREGEPRTKLIERNFRVLQSIIGGMQPIRPDAVILVVANPVD----ILTH 127
Query: 543 VLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
+ K PN+V+G T LD R +G++ V+P SV
Sbjct: 128 IAKTLSGLPPNQVIGSGTYLDTTRLRVHLGDVFDVNPQSV 167
>UniRef50_A3JXA9 Cluster: L-lactate dehydrogenase; n=1; Sagittula
stellata E-37|Rep: L-lactate dehydrogenase - Sagittula
stellata E-37
Length = 300
Score = 57.6 bits (133), Expect = 3e-07
Identities = 48/163 (29%), Positives = 75/163 (46%), Gaps = 5/163 (3%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAPV-TPGVAADLSHMNTPAKVSGH---KGPEELSAAI 353
+G A + + + L D+ A D++H P VS G ++LS A
Sbjct: 2 VGSAAAFACIMRGVASEIVLVDLDTARAQAEAEDIAHA-VPFSVSARIVAGGYDDLSGA- 59
Query: 354 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 533
DVV++ GV +KPG +R +L + NA + R + + + AP AI+ I +NPV+ I
Sbjct: 60 ---DVVILACGVSQKPGESRLELLSRNAEVFRAVVGDVTRAAPDAILLIASNPVD----I 112
Query: 534 ASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
+ V + RV+G T LD R +G + P SV
Sbjct: 113 MTHVTQALSGLPAGRVIGSGTILDTARFRWLLGRHLNIAPRSV 155
>UniRef50_P50933 Cluster: L-lactate dehydrogenase; n=7;
Bacteria|Rep: L-lactate dehydrogenase - Deinococcus
radiodurans
Length = 304
Score = 57.2 bits (132), Expect = 3e-07
Identities = 37/111 (33%), Positives = 56/111 (50%)
Frame = +3
Query: 321 HKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAI 500
H G EL+ DA VV++ AG +KPG +R DL NA I R++ I + AP A++ +
Sbjct: 59 HGGHSELA----DAQVVILTAGANQKPGESRLDLLEKNADIFRELVPQITRAAPDAVLLV 114
Query: 501 ITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVRAATFVGEINGVDPT 653
+NPV+ +A+++ V T LD R + + GVD T
Sbjct: 115 TSNPVDLLTDLATQLAPGQPVIGSG-----TVLDSARFRHLMAQHAGVDGT 160
>UniRef50_Q1IRL5 Cluster: L-lactate dehydrogenase; n=6;
Bacteria|Rep: L-lactate dehydrogenase - Acidobacteria
bacterium (strain Ellin345)
Length = 321
Score = 56.8 bits (131), Expect = 5e-07
Identities = 51/160 (31%), Positives = 70/160 (43%), Gaps = 2/160 (1%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIA-PVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 362
+G A L Q L + L D G A DL+H P + E A + A
Sbjct: 21 VGASFAFALLQRRLAAEIVLIDANHKKAEGEAMDLNHA-VPFGAATRIWAGEY-ADCRGA 78
Query: 363 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 542
V VI AG ++PG TR L + N +I + I + ++ P ++ I TNPV+ I S
Sbjct: 79 AVTVITAGAAQRPGETRLQLLDRNLAIFQQIVPEVVKHNPDGLLLIATNPVD----IISY 134
Query: 543 VLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
K +RVLG T LD R +G+ VD SV
Sbjct: 135 ASYKISGLPAHRVLGSGTILDTARFRYLLGQHFSVDARSV 174
>UniRef50_O51114 Cluster: L-lactate dehydrogenase; n=4; Borrelia
burgdorferi group|Rep: L-lactate dehydrogenase -
Borrelia burgdorferi (Lyme disease spirochete)
Length = 316
Score = 56.8 bits (131), Expect = 5e-07
Identities = 50/164 (30%), Positives = 76/164 (46%), Gaps = 6/164 (3%)
Frame = +3
Query: 186 IGQPLALLLK-QNPLVTRLALYDIAP-VTPGVAADLSHMNTPAKVSGHKGPEELSAAIKD 359
+G A L N LV L + D+ G DL+H K K L KD
Sbjct: 15 VGSSFAYALTIDNSLVHELVIIDVNENKAKGEVMDLNHGQMFLK----KNINVLFGTYKD 70
Query: 360 ---ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 530
AD+VVI AG+ +KPG TR DL + N+ I +DI ++ + I + +NPV+
Sbjct: 71 CANADIVVITAGLNQKPGETRLDLVDKNSKIFKDIITNVVSSGFDGIFVVASNPVD---- 126
Query: 531 IASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
I + V K + ++V+G T LD R F+ + V+ ++
Sbjct: 127 IMTYVTMKYSKFPIHKVIGTGTILDTSRLRYFLSDHFNVNTQNI 170
>UniRef50_UPI0000DB6C4F Cluster: PREDICTED: similar to Malate
DeHydrogenase family member (mdh-1); n=1; Apis
mellifera|Rep: PREDICTED: similar to Malate
DeHydrogenase family member (mdh-1) - Apis mellifera
Length = 221
Score = 56.4 bits (130), Expect = 6e-07
Identities = 25/72 (34%), Positives = 44/72 (61%)
Frame = +3
Query: 453 IALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVRAATFVGE 632
+A +AQ +++VA+ PV +T+P SE+ K AG +DP+R++G T LD +R
Sbjct: 1 MAEQMAQFNSESLVAVFVRPVTATLPTVSEIYKLAGWWDPDRIIGSTALDRMRMEALTAN 60
Query: 633 INGVDPTSVAVP 668
+ ++P ++VP
Sbjct: 61 LLDLNPAFLSVP 72
>UniRef50_Q03BE6 Cluster: L-lactate dehydrogenase; n=1;
Lactobacillus casei ATCC 334|Rep: L-lactate
dehydrogenase - Lactobacillus casei (strain ATCC 334)
Length = 312
Score = 56.0 bits (129), Expect = 8e-07
Identities = 36/99 (36%), Positives = 57/99 (57%), Gaps = 1/99 (1%)
Frame = +3
Query: 354 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 533
K AD++VI AG+ +KPG TR L NA I+++I +I + + + +NPV+ +
Sbjct: 70 KYADIIVITAGIAQKPGQTRLQLLAINAKIMKEITHNIMASGFNGFILVASNPVD---VL 126
Query: 534 ASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVD 647
A VL+++G+ N+VLG T LD R + +G VD
Sbjct: 127 AELVLQESGL-PRNQVLGSGTALDSARLRSEIGLRYNVD 164
>UniRef50_A4A2L6 Cluster: L-lactate dehydrogenase; n=4;
Bacteria|Rep: L-lactate dehydrogenase - Blastopirellula
marina DSM 3645
Length = 313
Score = 56.0 bits (129), Expect = 8e-07
Identities = 49/162 (30%), Positives = 77/162 (47%), Gaps = 4/162 (2%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 362
+G A L+ + +AL D+ A + G A DL H P+ V+ I D+
Sbjct: 12 VGSCAAFALQCGGIAREIALLDLNADLAGGHALDLLH-GAPS-VADQVITSGGYEHIPDS 69
Query: 363 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPK--AIVAIITNPVNSTVPIA 536
DV+ I AG+ RKP +R DL N N + I S+ K AI +++NPV+ +A
Sbjct: 70 DVICITAGLRRKPDESRLDLINRNVDLFLSILDSVKSAGVKKDAICFVVSNPVDILTYLA 129
Query: 537 SEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
++ L +RV+G+ T LD +R + + + PT V
Sbjct: 130 AQRLN----LPTSRVIGLGTQLDTIRFRALIAQEMKLPPTQV 167
>UniRef50_Q9EVR0 Cluster: L-lactate dehydrogenase; n=1; Selenomonas
ruminantium|Rep: L-lactate dehydrogenase - Selenomonas
ruminantium
Length = 318
Score = 56.0 bits (129), Expect = 8e-07
Identities = 48/165 (29%), Positives = 77/165 (46%), Gaps = 7/165 (4%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHMNT---PAKVSGHKGPEELSAAI 353
+G +A + L T + L D+ G A D SH + + H G E
Sbjct: 15 VGSAVANKIADFQLATEVVLIDLNEDKAWGEAKDSSHATSCIYSTNIKFHLGDYE---DC 71
Query: 354 KDADVVVIPAGVPRKPGMTRD--DLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTV 527
KDA+++VI AG +PG T D L TNA I+ + I + +A++ +ITNP++
Sbjct: 72 KDANIIVITAGPSIRPGETPDRLKLAGTNAKIMSSVMGEIVKRTKEAMIIMITNPLD--- 128
Query: 528 PIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
+A+ V+ Y N +LG T L+ R + + VDP ++
Sbjct: 129 -VATYVVSTQFDYPRNLILGTGTMLETYRFRRILADKYQVDPKNI 172
>UniRef50_Q87JV1 Cluster: Lactate dehydrogenase; n=4; Vibrio|Rep:
Lactate dehydrogenase - Vibrio parahaemolyticus
Length = 317
Score = 55.2 bits (127), Expect = 1e-06
Identities = 33/101 (32%), Positives = 55/101 (54%), Gaps = 1/101 (0%)
Frame = +3
Query: 360 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 539
AD+VVI AG + G TR D+ NA I +IA I + APKA++ +++NP + +A
Sbjct: 71 ADIVVITAGAQIQQGQTRLDIAEINAKIGVEIARKIERVAPKAVLIVVSNPCDI---VAH 127
Query: 540 EVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
+ G ++PN+V+ +D R + V +DP ++
Sbjct: 128 FITTNTG-FEPNKVISSGCVIDTARLMSIVANRVDLDPKNI 167
>UniRef50_A1HSK3 Cluster: Lactate/malate dehydrogenase; n=1;
Thermosinus carboxydivorans Nor1|Rep: Lactate/malate
dehydrogenase - Thermosinus carboxydivorans Nor1
Length = 303
Score = 55.2 bits (127), Expect = 1e-06
Identities = 31/90 (34%), Positives = 53/90 (58%), Gaps = 1/90 (1%)
Frame = +3
Query: 360 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 539
AD+VVI AG+PRK R L + NA+++ D+ +P I+ ++TNP++ +A
Sbjct: 68 ADIVVITAGIPRKADEPRVLLLSRNAALIADLVRQAVHYSPNCIIFMVTNPLDVMTQLAY 127
Query: 540 EVLKKAGVYDPNRVLGV-TTLDVVRAATFV 626
+V +G+ NRV+G+ T LD R +++
Sbjct: 128 QV---SGL-PANRVIGMGTVLDTARYRSYL 153
>UniRef50_P07864 Cluster: L-lactate dehydrogenase C chain; n=371;
Eukaryota|Rep: L-lactate dehydrogenase C chain - Homo
sapiens (Human)
Length = 332
Score = 55.2 bits (127), Expect = 1e-06
Identities = 44/159 (27%), Positives = 74/159 (46%), Gaps = 2/159 (1%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIA-PVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 362
+G A+ + L LAL D+A G DL H + S ++ S + ++
Sbjct: 31 VGMACAISILLKDLADELALVDVALDKLKGEMMDLQHGSLFFSTSKITSGKDYSVSA-NS 89
Query: 363 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 542
+V++ AG ++ G TR L N +I++ I +I +P + +++NPV+ I +
Sbjct: 90 RIVIVTAGARQQEGETRLALVQRNVAIMKSIIPAIVHYSPDCKILVVSNPVD----ILTY 145
Query: 543 VLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTS 656
++ K RV+G LD R +GE GV PTS
Sbjct: 146 IVWKISGLPVTRVIGSGCNLDSARFRYLIGEKLGVHPTS 184
>UniRef50_Q64YY6 Cluster: Malate dehydrogenase; n=5;
Bacteroidales|Rep: Malate dehydrogenase - Bacteroides
fragilis
Length = 333
Score = 54.0 bits (124), Expect = 3e-06
Identities = 46/144 (31%), Positives = 62/144 (43%), Gaps = 2/144 (1%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYD-IAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 362
IG +A L + LYD AP GVA +L H + ++ A+ A
Sbjct: 18 IGSNMAQTALMMKLTPNICLYDPYAPALEGVAEELYHCAFEGVNLTYTS--DIKEALSGA 75
Query: 363 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKA-IVAIITNPVNSTVPIAS 539
+V G RK GMTR+DL NA I I Q P V ++ NP + T I
Sbjct: 76 KYIVSSGGAARKAGMTREDLLKGNAEIAAQFGKDIRQYCPDVKHVVVVFNPADITGLI-- 133
Query: 540 EVLKKAGVYDPNRVLGVTTLDVVR 611
VL AG+ P++V + LD R
Sbjct: 134 -VLLYAGL-KPSQVSTLAALDSTR 155
>UniRef50_A2UB98 Cluster: Lactate/malate dehydrogenase precursor;
n=2; Bacteria|Rep: Lactate/malate dehydrogenase
precursor - Bacillus coagulans 36D1
Length = 327
Score = 52.8 bits (121), Expect = 7e-06
Identities = 40/130 (30%), Positives = 59/130 (45%), Gaps = 2/130 (1%)
Frame = +3
Query: 276 AADLSHM-NTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRD 452
A L++M NT K + + I A V+P+ P R L TNA++VR+
Sbjct: 51 ATALTYMPNTSVKAGDYSECADADVIICAAGPSVLPSEKDEMPD--RAGLARTNAAVVRE 108
Query: 453 IALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVG 629
+ I + +A++ ITNP+++ V IA Y R+ G T LD R V
Sbjct: 109 VMAGITKYTKEAVIIFITNPLDTIVYIAENEFG----YSKGRIFGTGTMLDSARLRQLVA 164
Query: 630 EINGVDPTSV 659
E +DP SV
Sbjct: 165 ENYSIDPKSV 174
>UniRef50_Q07841 Cluster: Malate dehydrogenase; n=7;
Halobacteriaceae|Rep: Malate dehydrogenase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 304
Score = 52.8 bits (121), Expect = 7e-06
Identities = 39/109 (35%), Positives = 58/109 (53%), Gaps = 1/109 (0%)
Frame = +3
Query: 264 TPGVAADLSH-MNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNAS 440
T G AAD +H + + +G E +A +DVVVI AG+PR+PG TR DL NA
Sbjct: 42 TVGQAADTNHGIAYDSNTRVRQGGYEDTAG---SDVVVITAGIPRQPGQTRIDLAGDNAP 98
Query: 441 IVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLG 587
I+ DI S+ ++ I +NPV+ + + L +AG +V+G
Sbjct: 99 IMEDIQSSLDEHNDDYISLTTSNPVD----LLNRHLYEAGDRSREQVIG 143
>UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4;
Bacteroidales|Rep: Malate dehydrogenase - Porphyromonas
gingivalis (Bacteroides gingivalis)
Length = 334
Score = 52.0 bits (119), Expect = 1e-05
Identities = 48/164 (29%), Positives = 69/164 (42%), Gaps = 2/164 (1%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYD-IAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 362
IG +A L L LYD A GVA ++ H ++ A+ DA
Sbjct: 18 IGSNMAQTAAMMRLTPNLCLYDPFAVGLEGVAEEIRHCGFEGL--NLTFTSDIKEALTDA 75
Query: 363 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKA-IVAIITNPVNSTVPIAS 539
+V G PRK GMTR+DL NA I + I P V II NP + T +
Sbjct: 76 KYIVSSGGAPRKEGMTREDLLKGNAEIAAQLGKDIKSYCPDCKHVIIIFNPADITGLV-- 133
Query: 540 EVLKKAGVYDPNRVLGVTTLDVVRAATFVGEINGVDPTSVAVPR 671
L +G+ P++V + LD R + + + G+ + V R
Sbjct: 134 -TLIYSGL-KPSQVTTLAGLDSTRLQSELAKHFGIKQSLVTNTR 175
>UniRef50_A3CTN0 Cluster: Lactate/malate dehydrogenase; n=1;
Methanoculleus marisnigri JR1|Rep: Lactate/malate
dehydrogenase - Methanoculleus marisnigri (strain ATCC
35101 / DSM 1498 / JR1)
Length = 288
Score = 51.6 bits (118), Expect = 2e-05
Identities = 45/161 (27%), Positives = 74/161 (45%), Gaps = 3/161 (1%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 362
+G A L LV + +YD+ P+ DL H +S +AA++DA
Sbjct: 12 VGGETAFLSAALGLVDEIVVYDVYEPLLRAQVLDLQHTGIDVAISTE------TAAMRDA 65
Query: 363 DVVVIPAGVPRKPGM-TRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 539
D+ V AG PR P + TR DL N + + + + + P +++ +TNP+++
Sbjct: 66 DIFVFAAGTPRTPDIKTRADLLEANIPVAKRCS-ELLEGFPGVVIS-VTNPMDAN---NY 120
Query: 540 EVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
+ K G+ D R +G + LD R A F+ E+ P V
Sbjct: 121 GLWKMMGI-DRRRCIGFGSQLDSARFAGFLREVGIPGPAWV 160
>UniRef50_A1U9V0 Cluster: Lactate/malate dehydrogenase; n=6;
Actinomycetales|Rep: Lactate/malate dehydrogenase -
Mycobacterium sp. (strain KMS)
Length = 329
Score = 51.2 bits (117), Expect = 2e-05
Identities = 40/135 (29%), Positives = 65/135 (48%), Gaps = 3/135 (2%)
Frame = +3
Query: 237 LALYDI--APVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMT 410
LALYD A V V DL+H + G ++++ A +VV+ AG + PG +
Sbjct: 46 LALYDTNSAKVRAEVL-DLNHGSQFVPECRVGGSDDIAVTAGSA-IVVVTAGAKQHPGQS 103
Query: 411 RDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGV 590
R DL N ++ + + + +++P A+V +TNPV+ AS V+ P ++ G
Sbjct: 104 RLDLAAANVAMAQTLTPQLLEHSPDAVVIFVTNPVDVVTYAASSVVDA----QPGQIFGT 159
Query: 591 -TTLDVVRAATFVGE 632
T LD R V +
Sbjct: 160 GTVLDSSRFRYLVAQ 174
>UniRef50_Q4JY42 Cluster: L-lactate dehydrogenase; n=1;
Corynebacterium jeikeium K411|Rep: L-lactate
dehydrogenase - Corynebacterium jeikeium (strain K411)
Length = 326
Score = 51.2 bits (117), Expect = 2e-05
Identities = 49/160 (30%), Positives = 68/160 (42%), Gaps = 2/160 (1%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 362
+G A L L LA+ D+ T G DL+H P + +DA
Sbjct: 26 VGIAYAYTLVNQGLTDHLAIIDLDERKTWGHVQDLNHA-VPWSHHNTRVTVGTYEDCRDA 84
Query: 363 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 542
+V I AG +KPG TR DL N +I + I + + I + +NPV+ I S
Sbjct: 85 AMVCICAGAAQKPGETRLDLVAKNTAIFKTIVGDVMSHGFNGIFLVASNPVD----ILSY 140
Query: 543 VLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
K D +RV+G T LD R +G + PTSV
Sbjct: 141 ATWKFSGMDSSRVIGSGTILDTARFRYALGRYFDLAPTSV 180
>UniRef50_P20619 Cluster: L-lactate dehydrogenase X; n=14;
Bacillales|Rep: L-lactate dehydrogenase X - Bacillus
psychrosaccharolyticus
Length = 319
Score = 51.2 bits (117), Expect = 2e-05
Identities = 50/176 (28%), Positives = 70/176 (39%), Gaps = 4/176 (2%)
Frame = +3
Query: 144 QRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSH--MNTPAKV 314
QRN +G A L + L + D+ G A DL+H + P
Sbjct: 3 QRNINRVALIGAGSVGSSYAFALLNQSITEELVIIDVNEDKAMGDAMDLNHGKIFAPNPT 62
Query: 315 SGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIV 494
G + K+AD+V I AG +KPG TR DL N I + + + + I
Sbjct: 63 KTWYGNYD---DCKEADIVCICAGANQKPGETRLDLVEKNLKIFKSLVDQVMASGFDGIF 119
Query: 495 AIITNPVNSTVPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
I TNPV+ I + K RV+G T LD R +GE + P +V
Sbjct: 120 LIATNPVD----ILTYATWKFSGLPKERVIGSGTILDSGRFRFLLGEYFDIAPANV 171
>UniRef50_Q4UJ29 Cluster: L-lactate dehydrogenase, putative; n=2;
Theileria|Rep: L-lactate dehydrogenase, putative -
Theileria annulata
Length = 367
Score = 50.8 bits (116), Expect = 3e-05
Identities = 32/84 (38%), Positives = 49/84 (58%), Gaps = 1/84 (1%)
Frame = +3
Query: 411 RDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGV 590
RDDL N+ I+RD+ +I + AP+A V +ITNP++ V + +LK G + N V+G+
Sbjct: 143 RDDLVGYNSKIIRDVGENIKKYAPEAFVIVITNPMDVMVHL---MLKVTG-FPKNMVVGM 198
Query: 591 -TTLDVVRAATFVGEINGVDPTSV 659
LD R ++ E GV+P V
Sbjct: 199 GGLLDSSRMNCYIAEKLGVNPKYV 222
>UniRef50_UPI000038D9FF Cluster: COG0039: Malate/lactate
dehydrogenases; n=2; Nostoc punctiforme PCC 73102|Rep:
COG0039: Malate/lactate dehydrogenases - Nostoc
punctiforme PCC 73102
Length = 317
Score = 50.4 bits (115), Expect = 4e-05
Identities = 34/96 (35%), Positives = 50/96 (52%), Gaps = 2/96 (2%)
Frame = +3
Query: 351 IKDADVVVI-PAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTV 527
+ D+D+++I AGV K G TR D + NA I+R + + AP +IV II+NPV+
Sbjct: 71 LADSDIIIIVTAGVQPKLGQTRLDTLSDNAEIIRSTIKELDRVAPNSIVIIISNPVDVLT 130
Query: 528 PIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGE 632
IA +A N + G T LD R +G+
Sbjct: 131 RIAQATSTRA----ENLIFGSGTVLDTARLRYQLGK 162
>UniRef50_UPI0000DB7268 Cluster: PREDICTED: similar to L-lactate
dehydrogenase A chain (LDH-A) (LDH muscle subunit)
(LDH-M); n=2; Apis mellifera|Rep: PREDICTED: similar to
L-lactate dehydrogenase A chain (LDH-A) (LDH muscle
subunit) (LDH-M) - Apis mellifera
Length = 348
Score = 50.0 bits (114), Expect = 5e-05
Identities = 45/156 (28%), Positives = 72/156 (46%), Gaps = 2/156 (1%)
Frame = +3
Query: 198 LALLLKQNPLVTRLALYDI-APVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVV 374
+A+L K+ L + L D+ + A D+SH G ++ S A +DA V V
Sbjct: 49 IAILFKR--LASELVFIDVNEELAKAEAEDISHGAAFLGNPKIIGTKDYSLA-RDATVCV 105
Query: 375 IPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKK 554
I G L N +I +D+ + + AP +I+ I+T PV+ I S K
Sbjct: 106 ITIGDRSTNEQDPSTLLEQNLNIFKDVIPKVCKYAPNSILLIVTAPVD----ILSYAAMK 161
Query: 555 AGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
+ P+RV+G+ T LD R F+ + G+ +SV
Sbjct: 162 LSGFPPHRVVGLGTFLDSCRFQYFIAQKLGISASSV 197
>UniRef50_Q97DC6 Cluster: L-lactate dehydrogenase 2; n=1;
Clostridium acetobutylicum|Rep: L-lactate dehydrogenase
2 - Clostridium acetobutylicum
Length = 320
Score = 50.0 bits (114), Expect = 5e-05
Identities = 43/149 (28%), Positives = 66/149 (44%), Gaps = 4/149 (2%)
Frame = +3
Query: 225 LVTRLALYDIAP-VTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKP 401
L++ + + DI G A D SH + A K DA ++VI AG KP
Sbjct: 29 LLSEVVIIDINDNKAKGEALDASHTTSFAYSPNVKVRAGNYEDCADAQIIVITAGPSLKP 88
Query: 402 GMTRDDLF--NTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPN 575
D L +TN + I +I + AI+ ++TNPV+ IA+ + Y N
Sbjct: 89 DDKLDRLVLADTNVKVTDSIMKNICKYTKDAIIIVVTNPVD----IATYYCQNNFDYPKN 144
Query: 576 RVLGV-TTLDVVRAATFVGEINGVDPTSV 659
+++G T LD R +G+ VD +V
Sbjct: 145 KIIGTGTLLDTARMRKIIGKKYNVDSKNV 173
>UniRef50_Q23CW4 Cluster: Malate dehydrogenase, cytoplasmic,
putative; n=3; Oligohymenophorea|Rep: Malate
dehydrogenase, cytoplasmic, putative - Tetrahymena
thermophila SB210
Length = 365
Score = 48.8 bits (111), Expect = 1e-04
Identities = 32/98 (32%), Positives = 44/98 (44%), Gaps = 1/98 (1%)
Frame = +3
Query: 261 VTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNAS 440
+ GV +L P S G E S +D DV V G PRKPGM R DL N +
Sbjct: 89 ILQGVELELQDGAYPLLKSIKTGSNE-SILFQDVDVAVFIGGFPRKPGMERKDLLTINGN 147
Query: 441 IVRDIALSIAQNAPKAIVA-IITNPVNSTVPIASEVLK 551
I + ++ A K + ++ NP N+ I +E K
Sbjct: 148 IFKKQGQALDTVAKKTCKSLVVANPANTNCLILAETAK 185
>UniRef50_P61973 Cluster: Malate dehydrogenase; n=43; Bacteria|Rep:
Malate dehydrogenase - Bdellovibrio bacteriovorus
Length = 335
Score = 48.4 bits (110), Expect = 2e-04
Identities = 31/92 (33%), Positives = 41/92 (44%), Gaps = 1/92 (1%)
Frame = +3
Query: 342 SAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA-PKAIVAIITNPVN 518
+ A KDADV ++ PR PGM R DL N I +I + A P V ++ NP N
Sbjct: 77 AVAFKDADVALLVGARPRGPGMERKDLLTANGQIFTVQGEAIGKYANPNVKVLVVGNPAN 136
Query: 519 STVPIASEVLKKAGVYDPNRVLGVTTLDVVRA 614
+ IA + K G + LD RA
Sbjct: 137 TNAYIAMKSAMKHGRVKAKNFTAMLRLDHNRA 168
>UniRef50_Q0UX88 Cluster: L-lactate dehydrogenase; n=2;
Phaeosphaeria nodorum|Rep: L-lactate dehydrogenase -
Phaeosphaeria nodorum (Septoria nodorum)
Length = 326
Score = 47.6 bits (108), Expect = 3e-04
Identities = 46/160 (28%), Positives = 73/160 (45%), Gaps = 2/160 (1%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 362
+G LA L + T + L D + G DLS T G + + A
Sbjct: 18 VGATLAYTLILQSICTEVLLVDPKTSLLDGQVRDLSDA-TSRSTKVRSGTHQEAG---QA 73
Query: 363 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 542
D+VVI AG +K G +R L N +I+ I S+ + ++ ++ NPV+ V A
Sbjct: 74 DIVVITAGAKQKTGESRLSLLTRNLNILSSIFDSMKPISAHTVLLLVANPVDILVYFARM 133
Query: 543 VLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
+ +G+ + N+VLG T+LD R + GV P+S+
Sbjct: 134 M---SGLPE-NQVLGTGTSLDSARLRGVLAGKAGVSPSSI 169
>UniRef50_Q9PHY2 Cluster: Probable malate dehydrogenase; n=12;
Campylobacter|Rep: Probable malate dehydrogenase -
Campylobacter jejuni
Length = 300
Score = 47.2 bits (107), Expect = 4e-04
Identities = 26/87 (29%), Positives = 46/87 (52%), Gaps = 1/87 (1%)
Frame = +3
Query: 354 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 533
K++D+V+ AG RK G +R++L N SI+ D A I + I+TNPV+ +
Sbjct: 68 KNSDIVLFSAGFARKDGQSREELLQLNTSIMLDCAKKIKDFTEDPLFIILTNPVDFLL-- 125
Query: 534 ASEVLKKAGVYDPNRVLGVT-TLDVVR 611
L ++G++ +++ + LD R
Sbjct: 126 --NTLYESGIFSSKKIIAMAGVLDNAR 150
>UniRef50_P47698 Cluster: L-lactate dehydrogenase; n=2;
Mycoplasma|Rep: L-lactate dehydrogenase - Mycoplasma
genitalium
Length = 312
Score = 47.2 bits (107), Expect = 4e-04
Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Frame = +3
Query: 351 IKDADVVVIPAGVPRKPG-MTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTV 527
+KD D + I AG P+K G TR L N I++ IA I ++ + I +NPV+
Sbjct: 69 LKDYDFIFISAGRPQKQGGETRLQLLEGNVEIMKSIAKEIKKSGFNGVTLIASNPVD--- 125
Query: 528 PIASEVLKKAGVYDPNRVLGVTTL 599
I S K ++PN+V+G TL
Sbjct: 126 -IMSYTYLKVTGFEPNKVIGSGTL 148
>UniRef50_Q4L941 Cluster: L-lactate dehydrogenase; n=1;
Staphylococcus haemolyticus JCSC1435|Rep: L-lactate
dehydrogenase - Staphylococcus haemolyticus (strain
JCSC1435)
Length = 318
Score = 46.8 bits (106), Expect = 5e-04
Identities = 49/166 (29%), Positives = 69/166 (41%), Gaps = 5/166 (3%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHMNTPAK---VSGHKGPEELSAAI 353
+G A + LV +A+ DI DL+H TP V+ H G E
Sbjct: 14 VGSAFAHAIVAKGLVDEMAIIDIDEDKAKADVWDLNHA-TPFGDNFVNVHVGQYE---DF 69
Query: 354 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 533
KDAD+VVI A G TR L N I + I + + +NPV+ I
Sbjct: 70 KDADIVVICASAKLAKGETRLKLLEDNVDIFVPMIQRIVDSGFDGYFVLPSNPVD----I 125
Query: 534 ASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSVAVP 668
S V+K+ + N+++G T+LD R F+ V P V P
Sbjct: 126 MSYVVKRVSNFPKNKIIGSGTSLDTARFQFFLSREFDVAPNQVYAP 171
>UniRef50_Q5M0L6 Cluster: L-2-hydroxyisocaproate dehydrogenase; n=3;
Streptococcus thermophilus|Rep: L-2-hydroxyisocaproate
dehydrogenase - Streptococcus thermophilus (strain CNRZ
1066)
Length = 316
Score = 46.4 bits (105), Expect = 6e-04
Identities = 35/109 (32%), Positives = 52/109 (47%), Gaps = 4/109 (3%)
Frame = +3
Query: 348 AIKDADVVVIPAG---VPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 518
A+KDADV++ G + G R F V +A + Q K I+ +I+NPV+
Sbjct: 67 ALKDADVIISALGNIQLQHNAGEDRFAEFPFTREAVYQVAQELKQLDFKGILLVISNPVD 126
Query: 519 STVPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSVA 662
+ + E + RV+G T LD R T VGE+ V+P SV+
Sbjct: 127 AVTALYQEFTG----WPKERVIGTGTLLDTARMKTAVGEVLEVNPKSVS 171
>UniRef50_O52354 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
gallisepticum|Rep: L-lactate dehydrogenase - Mycoplasma
gallisepticum
Length = 323
Score = 46.4 bits (105), Expect = 6e-04
Identities = 33/110 (30%), Positives = 53/110 (48%), Gaps = 7/110 (6%)
Frame = +3
Query: 351 IKDADVVVIPAGVPRKPG------MTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNP 512
+KDADVV I A +P P R L N I+ +IAL + + K + I TNP
Sbjct: 68 LKDADVVAITASIPTVPTADGEVFTDRLQLMTANVKILNEIALELKRVGFKGLSIIPTNP 127
Query: 513 VNSTVPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
+ + + V +K +DP++++ L+ +R + E GV+ SV
Sbjct: 128 CD----VMAGVYQKVTGFDPHKIISTGCQLETMRTRKMISEALGVNSDSV 173
>UniRef50_Q7QQW5 Cluster: Malate dehydrogenase; n=2; Giardia
intestinalis|Rep: Malate dehydrogenase - Giardia lamblia
ATCC 50803
Length = 331
Score = 45.6 bits (103), Expect = 0.001
Identities = 38/125 (30%), Positives = 58/125 (46%), Gaps = 1/125 (0%)
Frame = +3
Query: 270 GVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVR 449
GVA +L P +SG + + A KD D ++ PRK GM R +L + N I +
Sbjct: 53 GVAMELVDCAFPL-LSGFTLTSDNAEAFKDVDYCLLFGAFPRKAGMERAELLSKNKGIFQ 111
Query: 450 DIALSIAQNA-PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVRAATFV 626
+I ++A P + +I NP N+ + S L K V ++ LD RA V
Sbjct: 112 IQGAAINEHAKPTCRILVIGNPANTNALVLSTQLTK---IPKTNVTAMSRLDHNRA---V 165
Query: 627 GEING 641
G++ G
Sbjct: 166 GQVAG 170
>UniRef50_Q5B0T8 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 237
Score = 45.2 bits (102), Expect = 0.001
Identities = 48/170 (28%), Positives = 68/170 (40%), Gaps = 5/170 (2%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 362
+G A L + L L D A G DLS A + SA ++A
Sbjct: 18 VGAAAAYALVLGSIADELLLVDTRAAWRDGQVRDLSD----AAYASRSKTRVYSATYREA 73
Query: 363 ---DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 533
D+VVI AG G T D N SIVR I + ++ I+ NPV+ +
Sbjct: 74 SQCDIVVITAGSKYLYGQTSMDYLYRNTSIVRSIINEMKPFRSDTVLLIVANPVDLMTSL 133
Query: 534 ASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSVAVPRHRR 680
A E+ +VLG T LD +R + + GV+ + +P H R
Sbjct: 134 AKELSNLPSA----QVLGSGTFLDSIRLRGLLADETGVNKNWLLLPLHPR 179
>UniRef50_P59050 Cluster: L-lactate dehydrogenase 1; n=3;
Bifidobacterium longum|Rep: L-lactate dehydrogenase 1 -
Bifidobacterium longum
Length = 316
Score = 45.2 bits (102), Expect = 0.001
Identities = 31/106 (29%), Positives = 52/106 (49%), Gaps = 1/106 (0%)
Frame = +3
Query: 345 AAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNST 524
A KDAD+VVI G R +V ++ ++ + ++ +++NPV+
Sbjct: 70 ADCKDADIVVITVGRKPPANSNRMAELGFTVGLVGEVVDNVMASGFDGVIVMVSNPVD-- 127
Query: 525 VPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
+A K++G+ +VLG T LD R T +GE G+DP +V
Sbjct: 128 -VMAWYAWKRSGL-PRTQVLGTGTALDTSRLKTIIGEETGLDPRNV 171
>UniRef50_Q014D4 Cluster: Chromosome 08 contig 1, DNA sequence; n=3;
Eukaryota|Rep: Chromosome 08 contig 1, DNA sequence -
Ostreococcus tauri
Length = 1453
Score = 44.8 bits (101), Expect = 0.002
Identities = 38/133 (28%), Positives = 60/133 (45%)
Frame = -1
Query: 572 RVVHSRLLEHFRGNRHCRVNRVCDDGHNSFGCILSNGQSNVTDNGSISVE*VITGHSRFT 393
RVV + LEH RG+ + V+ V D H G S+ + ++ + E V+ H+R
Sbjct: 5 RVVTTASLEHLRGDGNRGVHGVGYDVHQRVGTRTSDRFAERANDPGVDAEQVVPRHARLA 64
Query: 392 GYSCWDDYNISIFDGC**LLRSLVAADLGWGVHVGKVGCDAGGHRRYVV*SQPGHQRILL 213
+ DD ++ L S V A ++V +V H R VV S+ H R+ L
Sbjct: 65 RHPGGDDDQVAPSQTRVQLGVSHVRAHFRSRINVRQVHPHPSDHGRDVVQSELSHARVRL 124
Query: 212 Q*KGQRLADTTGG 174
+ +RL D + G
Sbjct: 125 DERRERLTDPSRG 137
>UniRef50_Q0PQR8 Cluster: Malate dehydrogenase NAD-dependent; n=1;
Endoriftia persephone 'Hot96_1+Hot96_2'|Rep: Malate
dehydrogenase NAD-dependent - Endoriftia persephone
'Hot96_1+Hot96_2'
Length = 170
Score = 44.4 bits (100), Expect = 0.003
Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Frame = +3
Query: 414 DDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVT 593
DDL + N S+ + +A ++ Q+AP A V + TNP++S V K R++G+
Sbjct: 16 DDLLDINLSVTKKVATAVKQHAPDAFVILTTNPLDSIV----YAFHKLSGLPAERIIGMA 71
Query: 594 -TLDVVRAATFVGEINGVDPTSVA 662
LD R T++ G+ V+
Sbjct: 72 GALDTARFRTYIAMETGLSVKDVS 95
>UniRef50_Q017A7 Cluster: Chromosome 06 contig 1, DNA sequence; n=1;
Ostreococcus tauri|Rep: Chromosome 06 contig 1, DNA
sequence - Ostreococcus tauri
Length = 131
Score = 44.4 bits (100), Expect = 0.003
Identities = 22/37 (59%), Positives = 24/37 (64%)
Frame = -2
Query: 376 MTTTSASLMAADSSSGPLWPLTLAGVFMWERSAATPG 266
M TTS S AA SS+ P +P T A VF E SAATPG
Sbjct: 1 MITTSQSFSAAPSSASPAYPFTCAAVFTCETSAATPG 37
>UniRef50_A2E124 Cluster: Malate dehydrogenase; n=6;
Trichomonadidae|Rep: Malate dehydrogenase - Trichomonas
vaginalis G3
Length = 332
Score = 44.4 bits (100), Expect = 0.003
Identities = 32/112 (28%), Positives = 48/112 (42%), Gaps = 1/112 (0%)
Frame = +3
Query: 327 GPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA-PKAIVAII 503
G +L A +D DV + P+KP D F NASI + +++ A P V +I
Sbjct: 69 GTSDLEEAFRDVDVAFLVGSFPKKPSTKLVDYFQRNASIYSEHGRALSDFAKPTVKVLVI 128
Query: 504 TNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVRAATFVGEINGVDPTSV 659
P N+ +A + A P +T LD RA + + GV + V
Sbjct: 129 GMPTNTNALVA---MTAAVNLSPKNFCAMTRLDHNRAVYSIAQKLGVHHSKV 177
>UniRef50_A0D8T3 Cluster: Malate dehydrogenase; n=2; Paramecium
tetraurelia|Rep: Malate dehydrogenase - Paramecium
tetraurelia
Length = 322
Score = 44.4 bits (100), Expect = 0.003
Identities = 22/59 (37%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Frame = +3
Query: 348 AIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAI-VAIITNPVNS 521
A KDADV + +PRKPGM R DL N I + + A + V ++ NP N+
Sbjct: 79 AFKDADVAIFLGAMPRKPGMERSDLLQMNREIFIQQGQILNEQAKSTVKVLVVANPSNT 137
>UniRef50_Q9GPV2 Cluster: Cytosolic malate dehydrogenase; n=4;
Trichomonadida|Rep: Cytosolic malate dehydrogenase -
Tetratrichomonas gallinarum
Length = 314
Score = 43.6 bits (98), Expect = 0.005
Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +3
Query: 312 VSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAI 491
V+G +++ A KD DV + PRK GM R DL N I +++ A K +
Sbjct: 46 VAGIVWTDKIEEAFKDVDVAFLVGSFPRKDGMDRSDLLAKNGGIFTVQGKALSDFAKKDV 105
Query: 492 -VAIITNPVNSTVPIA 536
V ++ NP N+ IA
Sbjct: 106 KVLVVGNPANTNCLIA 121
>UniRef50_Q5FIY9 Cluster: L-LDH; n=6; Lactobacillus|Rep: L-LDH -
Lactobacillus acidophilus
Length = 304
Score = 43.2 bits (97), Expect = 0.006
Identities = 31/106 (29%), Positives = 50/106 (47%), Gaps = 3/106 (2%)
Frame = +3
Query: 351 IKDADVVVIPAGVPRKPGMTRDDL--FNTNASIVRDIALSIAQNAPKAIVAIITNPVNST 524
+KDAD++V G T D F NA +++ I K ++ I+NP ++
Sbjct: 67 LKDADIIVTAFGDIAASVKTGDRFGEFELNAKNAKEVGEKIKNTGFKGVLLNISNPCDAV 126
Query: 525 VPIASEVLKKAGVYDPNRVLGVTT-LDVVRAATFVGEINGVDPTSV 659
+++L++ N+VLG T LD R +GE G DP +V
Sbjct: 127 ----AQILQETTGLSKNQVLGTGTFLDTARMQRIIGEKLGQDPKNV 168
>UniRef50_O34358 Cluster: Probable serine protease do-like htrA;
n=1; Bacillus subtilis|Rep: Probable serine protease
do-like htrA - Bacillus subtilis
Length = 449
Score = 43.2 bits (97), Expect = 0.006
Identities = 33/108 (30%), Positives = 50/108 (46%)
Frame = +3
Query: 282 DLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIAL 461
DLS T VSG +S + + + VI PG + L NT+ IV ++
Sbjct: 248 DLSRTVTQGIVSGVDRTVSMSTSAGETSINVIQTDAAINPGNSGGPLLNTDGKIVGINSM 307
Query: 462 SIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDV 605
I+++ + I I P N PIA E+L K + P +GV+ LD+
Sbjct: 308 KISEDDVEGIGFAI--PSNDVKPIAEELLSKGQIERP--YIGVSMLDL 351
>UniRef50_UPI00015974E8 Cluster: HtrA; n=1; Bacillus
amyloliquefaciens FZB42|Rep: HtrA - Bacillus
amyloliquefaciens FZB42
Length = 450
Score = 42.7 bits (96), Expect = 0.008
Identities = 32/108 (29%), Positives = 51/108 (47%)
Frame = +3
Query: 282 DLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIAL 461
DLS T VSG +S + ++ + VI PG + L NT+ I+ ++
Sbjct: 249 DLSRTVTQGIVSGLNRTVSISTSAGESSINVIQTDAAINPGNSGGPLLNTDGKIIGINSM 308
Query: 462 SIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDV 605
I+++ + I I P N PIA E+L K V P +GV+ +D+
Sbjct: 309 KISESDVEGIGFAI--PSNDVKPIAEELLTKGQVERP--YIGVSMIDL 352
>UniRef50_UPI0000DB7267 Cluster: PREDICTED: similar to
Ecdysone-inducible gene L3 CG10160-PA; n=1; Apis
mellifera|Rep: PREDICTED: similar to Ecdysone-inducible
gene L3 CG10160-PA - Apis mellifera
Length = 368
Score = 42.7 bits (96), Expect = 0.008
Identities = 42/161 (26%), Positives = 70/161 (43%), Gaps = 2/161 (1%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 362
IG A+ + + + + L D A A D+ H+ G E+S + A
Sbjct: 59 IGIACAIAILMRRMASEVCLIDHDANKASAEAEDIQHVGFFLGCPLVTGTSEISTVKESA 118
Query: 363 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 542
V++ P PG ++ N + + I +IA+ A K+++ I+T P + + S
Sbjct: 119 VVIICTPETP--PGENQN--VKHNLKVFKKIIPAIARFAAKSVLLIVTRPAD----VMSY 170
Query: 543 VLKKAGVYDPNRVLGVTTL-DVVRAATFVGEINGVDPTSVA 662
+ K + NRVLG+ TL D R FV V +SV+
Sbjct: 171 IAWKLSGFPSNRVLGIGTLIDCARLQDFVSRRLNVARSSVS 211
>UniRef50_A2QJT7 Cluster: Catalytic activity: precursor; n=1;
Aspergillus niger|Rep: Catalytic activity: precursor -
Aspergillus niger
Length = 307
Score = 42.7 bits (96), Expect = 0.008
Identities = 31/95 (32%), Positives = 48/95 (50%), Gaps = 1/95 (1%)
Frame = +3
Query: 360 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 539
ADVV+I AGV PG T SI++ I + P AI+ ++ NPV++ +A
Sbjct: 70 ADVVIITAGVNYTPGETTLQHLYHKFSILKSILNEMRPFNPNAIILVVANPVDTLTTLAQ 129
Query: 540 EVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEING 641
++ AG+ +V+GV T +D +R V G
Sbjct: 130 DI---AGL-PRKQVIGVGTCIDSLRLQDEVSRFLG 160
>UniRef50_A2SR33 Cluster: Lactate/malate dehydrogenase; n=1;
Methanocorpusculum labreanum Z|Rep: Lactate/malate
dehydrogenase - Methanocorpusculum labreanum (strain
ATCC 43576 / DSM 4855 / Z)
Length = 283
Score = 41.9 bits (94), Expect = 0.014
Identities = 44/166 (26%), Positives = 72/166 (43%), Gaps = 3/166 (1%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIA-PVTPGVAADLSH-MNTPAKVSGHKGPEELSAAIKD 359
IG +A + L L+DI+ P+ D+ H M+ P + A +KD
Sbjct: 12 IGGEVAYVSALRKFADELVLFDISEPLQHAQKLDIIHGMDIPVSTN--------PADLKD 63
Query: 360 ADVVVIPAGVPRKPGM-TRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIA 536
AD + AG R P + TR DLF+ N I ++ + + + K IV +TNP++ +
Sbjct: 64 ADYCIFSAGYSRSPNIKTRADLFDKNLPIAKESSELLKGFSGKLIV--VTNPMD----VF 117
Query: 537 SEVLKKAGVYDPNRVLGVTTLDVVRAATFVGEINGVDPTSVAVPRH 674
+ K D ++V+G L R T V G++ + H
Sbjct: 118 TWYFAKKSCLDESQVVGFGGLLDSRRFTVVLRSIGIEAEGQVLGEH 163
>UniRef50_A1W9K7 Cluster: Malate dehydrogenase; n=95; cellular
organisms|Rep: Malate dehydrogenase - Acidovorax sp.
(strain JS42)
Length = 328
Score = 41.5 bits (93), Expect = 0.018
Identities = 34/118 (28%), Positives = 51/118 (43%), Gaps = 1/118 (0%)
Frame = +3
Query: 270 GVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVR 449
GV +L P ++G + + A KD D ++ PR PGM R DL NA I
Sbjct: 55 GVIMELEDCAFPL-LAGIEAHSDPMTAFKDTDYALLVGARPRGPGMERADLLAANAQIFT 113
Query: 450 DIALSIAQNAPKAI-VAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVRAAT 620
++ A + + V ++ NP N+ IA +K A + LD RAA+
Sbjct: 114 AQGKALNAVASRNVKVLVVGNPANTNAYIA---MKSAPDLPAKNFTAMLRLDHNRAAS 168
>UniRef50_Q6A6E3 Cluster: L-lactate dehydrogenase; n=1;
Propionibacterium acnes|Rep: L-lactate dehydrogenase -
Propionibacterium acnes
Length = 321
Score = 41.1 bits (92), Expect = 0.024
Identities = 35/110 (31%), Positives = 49/110 (44%), Gaps = 7/110 (6%)
Frame = +3
Query: 351 IKDADVVVIPAG----VPRKP--GMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNP 512
+ +ADV+++ AG P G R +L TN I+R I A + I +NP
Sbjct: 72 LSNADVIIMTAGPSIDASNGPATGAARRELAATNGKIIRSTMTQITSRNHDAAIIICSNP 131
Query: 513 VNSTVPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
+++ V IAS + VLG T LD R V + GVDP V
Sbjct: 132 LDALVHIASTEFD----HPQGLVLGTGTILDSARMCRVVADHLGVDPDYV 177
>UniRef50_P14295 Cluster: L-2-hydroxyisocaproate dehydrogenase;
n=15; Lactobacillales|Rep: L-2-hydroxyisocaproate
dehydrogenase - Lactobacillus confusus
Length = 310
Score = 39.9 bits (89), Expect = 0.056
Identities = 29/111 (26%), Positives = 56/111 (50%), Gaps = 5/111 (4%)
Frame = +3
Query: 345 AAIKDADVVVIPAG-VPRKPGMTRDDLF---NTNASIVRDIALSIAQNAPKAIVAIITNP 512
AA+ DADVV+ G + + D F +S+V+ + ++ ++ ++ +I+NP
Sbjct: 66 AALADADVVISTLGNIKLQQDNPTGDRFAELKFTSSMVQSVGTNLKESGFHGVLVVISNP 125
Query: 513 VNSTVPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSVA 662
V+ + + + + + ++V+G T LD R VGE +DP SV+
Sbjct: 126 VD----VITALFQHVTGFPAHKVIGTGTLLDTARMQRAVGEAFDLDPRSVS 172
>UniRef50_Q03ZZ4 Cluster: Enzyme with possible activities of L-2-
hydroxyisocaproate/malate/lactate dehydrogenase; n=3;
Lactobacillales|Rep: Enzyme with possible activities of
L-2- hydroxyisocaproate/malate/lactate dehydrogenase -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 304
Score = 39.1 bits (87), Expect = 0.098
Identities = 28/107 (26%), Positives = 49/107 (45%), Gaps = 3/107 (2%)
Frame = +3
Query: 351 IKDADVVVIPAGVPR--KPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNST 524
+ DA+VV+ G KPG R N V+ + + Q ++ +I+NPV+
Sbjct: 67 LTDAEVVISALGHIELIKPGGDRFTELKANTPEVQQVGSDLKQAGFNGVLIVISNPVD-- 124
Query: 525 VPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSVA 662
+ + + +KA N+V G T LD R +G+ +DP ++
Sbjct: 125 --VITGIYQKATGLPANQVFGTGTYLDTARLKRALGDTLAIDPRGIS 169
>UniRef50_A7DSJ4 Cluster: Lactate/malate dehydrogenase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
Lactate/malate dehydrogenase - Candidatus Nitrosopumilus
maritimus SCM1
Length = 303
Score = 39.1 bits (87), Expect = 0.098
Identities = 35/160 (21%), Positives = 75/160 (46%), Gaps = 1/160 (0%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDAD 365
+G +A L N L L + G + D++ +G ++ S I +D
Sbjct: 13 VGASIAFLCVSNGLDDVLLVNTTKEKAIGESLDVASAIPANSKFSIRGTDDYSELI-GSD 71
Query: 366 VVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEV 545
+V+I A V +++ + +++++IA I + P AIV +++NP++ + +
Sbjct: 72 IVIIAASVGIYTKHRAENI-DHQVAMIKNIAKKIKKYCPSAIVLLVSNPLD----VLTYF 126
Query: 546 LKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSVA 662
+K + +V+G+ ++LD R ++ E V +SV+
Sbjct: 127 FQKTTGFSRFKVIGIASSLDTSRFRYYISETLSVPQSSVS 166
>UniRef50_Q9CGG8 Cluster: L-lactate dehydrogenase 3; n=3;
Lactococcus lactis|Rep: L-lactate dehydrogenase 3 -
Lactococcus lactis subsp. lactis (Streptococcus lactis)
Length = 323
Score = 37.5 bits (83), Expect = 0.30
Identities = 30/107 (28%), Positives = 48/107 (44%), Gaps = 4/107 (3%)
Frame = +3
Query: 351 IKDADVVVIPAGVPRKP-GMTRD--DLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNS 521
+ DAD+VV+ A P G D L ++RDI I + +NPV+
Sbjct: 72 VSDADIVVLSANAPSATFGKNPDRLQLLENKVEMIRDITRKTMDAGFDGIFLVASNPVDV 131
Query: 522 TVPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVDPTSV 659
+ +EV +G+ +RV+G T L+ R V E ++P S+
Sbjct: 132 LAQVVAEV---SGL-PKHRVIGTGTLLETSRMRQIVAEKLQINPKSI 174
>UniRef50_Q4DTK0 Cluster: Putative uncharacterized protein; n=1;
Trypanosoma cruzi|Rep: Putative uncharacterized protein
- Trypanosoma cruzi
Length = 492
Score = 36.7 bits (81), Expect = 0.52
Identities = 19/74 (25%), Positives = 36/74 (48%)
Frame = +3
Query: 333 EELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNP 512
++LS A+ D D VV G +D+ S ++D+ LSI +N ++ +P
Sbjct: 173 DDLSLAVADCDGVVYVNGPDTSEISNENDIERLFVSSIQDVFLSIKRNGKSVRRVVLISP 232
Query: 513 VNSTVPIASEVLKK 554
+S P+ + ++ K
Sbjct: 233 ASSIFPVETTLVAK 246
>UniRef50_Q9Z6N1 Cluster: Malate dehydrogenase; n=8;
Chlamydiaceae|Rep: Malate dehydrogenase - Chlamydia
pneumoniae (Chlamydophila pneumoniae)
Length = 328
Score = 36.3 bits (80), Expect = 0.69
Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 2/68 (2%)
Frame = +3
Query: 339 LSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASI--VRDIALSIAQNAPKAIVAIITNP 512
L+ A D + VPR PGM R DL N I ++ AL+ A A + ++ NP
Sbjct: 76 LNDAFDGIDAAFLIGAVPRGPGMERGDLLKQNGQIFSLQGAALNTAAKR-DAKIFVVGNP 134
Query: 513 VNSTVPIA 536
VN+ IA
Sbjct: 135 VNTNCWIA 142
>UniRef50_Q46780 Cluster: BfpF; n=4; Enterobacteriaceae|Rep: BfpF -
Escherichia coli
Length = 331
Score = 35.9 bits (79), Expect = 0.91
Identities = 25/94 (26%), Positives = 44/94 (46%), Gaps = 3/94 (3%)
Frame = -1
Query: 671 TGHGDG--GRVHAID-LADEGGSADYVQSGDAEHAVRVVHSRLLEHFRGNRHCRVNRVCD 501
T HG G ++A+ +A G AD V+S A+ + +VH L G R N +C+
Sbjct: 235 TIHGSSVQGAIYALQQIASAEGEADLVRSIIADGLLGIVHQELRFTENGQRSLSANILCN 294
Query: 500 DGHNSFGCILSNGQSNVTDNGSISVE*VITGHSR 399
DG S + +G+ + + I + ++ H +
Sbjct: 295 DGSASISSKIRSGKLELL-SSEIEQQRIMLSHGK 327
>UniRef50_UPI0001554DCB Cluster: PREDICTED: similar to Zinc finger
protein 160, partial; n=1; Ornithorhynchus anatinus|Rep:
PREDICTED: similar to Zinc finger protein 160, partial -
Ornithorhynchus anatinus
Length = 912
Score = 35.5 bits (78), Expect = 1.2
Identities = 17/43 (39%), Positives = 21/43 (48%)
Frame = +2
Query: 200 GPSTEAESSGDQAGFIRHSACDPRRRSRPFPHEHPSQGQRPQG 328
GP S G G +R+SA DP RRS P P +R +G
Sbjct: 143 GPGEPVRSGGAGEGAVRNSALDPTRRSHPSPIPPRGSRERDEG 185
>UniRef50_A6W5C7 Cluster: D-alanyl-D-alanine
carboxypeptidase/D-alanyl-D-alanine-endopeptidase
precursor; n=1; Kineococcus radiotolerans SRS30216|Rep:
D-alanyl-D-alanine
carboxypeptidase/D-alanyl-D-alanine-endopeptidase
precursor - Kineococcus radiotolerans SRS30216
Length = 478
Score = 35.5 bits (78), Expect = 1.2
Identities = 45/164 (27%), Positives = 65/164 (39%), Gaps = 7/164 (4%)
Frame = +3
Query: 195 PLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAI-KDADVV 371
P A L P TR D PV P + D + PA + G P A+
Sbjct: 40 PTAAPLPTAPGATRPTQADTPPVLPALDPDAPRPD-PAALGGVVAPLLADPALGASVSTS 98
Query: 372 VIPAGVPRKPGMTRDDLFNTNASIVRDI----ALSIAQNAPKAIVAIITNPVNSTVPIAS 539
V+ A T D+ T AS+ + + AL +A +++ V + +
Sbjct: 99 VVDALTGETLLATAADVPRTPASVAKLLTAVAALHTLGPTSRATTSVVDGATPDEVVLVA 158
Query: 540 --EVLKKAGVYDPNRVLGVTTLDVVRAATFVGEINGVDPTSVAV 665
+VL AG DP+ V G LD + AAT E+ T+VAV
Sbjct: 159 GGDVLLAAGAGDPDAVDGHAGLDDLAAAT-AAELLAAGRTAVAV 201
>UniRef50_Q8IE66 Cluster: Oxidoreductase, putative; n=6;
Plasmodium|Rep: Oxidoreductase, putative - Plasmodium
falciparum (isolate 3D7)
Length = 334
Score = 35.5 bits (78), Expect = 1.2
Identities = 37/144 (25%), Positives = 72/144 (50%), Gaps = 9/144 (6%)
Frame = +3
Query: 186 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHMNTPAKVSGHK--GPEELSAAIK 356
IG LA ++ + L + L+D P G A D+ H P S G E++ IK
Sbjct: 17 IGCALAHMICEKNLGD-VVLHDFRKDLPKGRALDILHTR-PLNRSRINILGTNEITD-IK 73
Query: 357 DADVVVIPAGVPRKPGMTRDD------LFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 518
D+ VVV+ V + D+ ++ +N +++++A S+ ++ P+A V + T+PV+
Sbjct: 74 DSLVVVVTIEVSEREFAEFDEEDLEKQVYTSNVKLLKEVAKSLKKHCPQAFVVVTTSPVD 133
Query: 519 STVPIASEVLKKAGVYDPNRVLGV 590
++VL++ P+++ G+
Sbjct: 134 ----CMAKVLQEHANIPPHKICGM 153
>UniRef50_A5IYS9 Cluster: L-lactate dehydrogenase; n=2;
Mycoplasma|Rep: L-lactate dehydrogenase - Mycoplasma
agalactiae
Length = 323
Score = 35.1 bits (77), Expect = 1.6
Identities = 23/62 (37%), Positives = 29/62 (46%), Gaps = 1/62 (1%)
Frame = +3
Query: 330 PEELSAAIKDADVVVIPAGVPR-KPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIIT 506
P L KDADVVVI A +P K R L NA +++ A + K IV +
Sbjct: 62 PGTLLEDSKDADVVVITASIPADKTFSDRMALAGANAKLMQSFAKDLDAAGFKGIVVVAA 121
Query: 507 NP 512
NP
Sbjct: 122 NP 123
>UniRef50_Q91PS6 Cluster: ORF4; n=2; Torque teno virus|Rep: ORF4 -
Torque teno virus
Length = 279
Score = 34.7 bits (76), Expect = 2.1
Identities = 25/60 (41%), Positives = 33/60 (55%), Gaps = 6/60 (10%)
Frame = -1
Query: 680 PPMTGHGDGGRVHAIDLADEGGSA--DYVQSGDAEHAVRVVH----SRLLEHFRGNRHCR 519
PP G G GGR D AD+GG A D QSGD + ++ S+ ++ RG+RHCR
Sbjct: 82 PPSCG-GTGGRGAGGDRADDGGRADGDDFQSGDVGELLDMLDDAEPSKKIK-IRGSRHCR 139
>UniRef50_Q8NQ95 Cluster: Predicted nucleoside-diphosphate-sugar
epimerases; n=4; Corynebacterium|Rep: Predicted
nucleoside-diphosphate-sugar epimerases -
Corynebacterium glutamicum (Brevibacterium flavum)
Length = 221
Score = 34.7 bits (76), Expect = 2.1
Identities = 34/110 (30%), Positives = 52/110 (47%), Gaps = 5/110 (4%)
Frame = +3
Query: 333 EELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVR-DIALSIAQNAPKAI-VAIIT 506
E+ + +KD DVVV AG K G + +A+I D A S+ + AP+ I V+ I
Sbjct: 62 EDWADLLKDFDVVVWSAGNGGKNGADATYAIDRDAAIASIDGAASLGEKAPRYIMVSYIG 121
Query: 507 NPVNSTVPIASEVLKKAGVYDPNRVLGVTTLD---VVRAATFVGEINGVD 647
+ ++ P AS + L T LD + AA + E+NGV+
Sbjct: 122 SSTHTIDPSASFYPYAESKKAADEHLSSTNLDYLILAPAALTLDEVNGVE 171
>UniRef50_UPI000049A32B Cluster: protein kinase; n=1; Entamoeba
histolytica HM-1:IMSS|Rep: protein kinase - Entamoeba
histolytica HM-1:IMSS
Length = 1054
Score = 34.3 bits (75), Expect = 2.8
Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 3/40 (7%)
Frame = -1
Query: 551 LEHFRGNRHCRVNRVCDDGHNS---FGCILSNGQSNVTDN 441
+E F N HC N C DG+N+ F C+ S+ + + DN
Sbjct: 457 VECFSYNNHCLTNCKCQDGYNATSLFSCVTSSCGNGINDN 496
>UniRef50_UPI0000D8BD94 Cluster: UPI0000D8BD94 related cluster; n=2;
Danio rerio|Rep: UPI0000D8BD94 UniRef100 entry - Danio
rerio
Length = 732
Score = 34.3 bits (75), Expect = 2.8
Identities = 30/116 (25%), Positives = 49/116 (42%), Gaps = 4/116 (3%)
Frame = +3
Query: 189 GQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHK---GPEELSAAIKD 359
G P A+LL NP T+L + P+ H N A+++GH + S +
Sbjct: 285 GMPNAVLLSSNPNQTQLNQLTLNPLQLN-----HHPNCSAQLTGHPLTLPRPKFSYMNTN 339
Query: 360 ADVVVIPAGVPRKPGMTRDDLFN-TNASIVRDIALSIAQNAPKAIVAIITNPVNST 524
V+ G + + D FN TN ++ ++ I+ PK ++ PVN T
Sbjct: 340 GSAAVVFLGYTAMENLLKADFFNATNDTVNTMMSSVISVTLPKTTNTALSKPVNFT 395
>UniRef50_Q0JLJ7 Cluster: Os01g0595100 protein; n=6; Oryza
sativa|Rep: Os01g0595100 protein - Oryza sativa subsp.
japonica (Rice)
Length = 837
Score = 34.3 bits (75), Expect = 2.8
Identities = 37/125 (29%), Positives = 57/125 (45%), Gaps = 1/125 (0%)
Frame = +3
Query: 288 SHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRK-PGMTRDDLFNTNASIVRDIALS 464
+H N P KV +GP A K+ VV G RK P +R+ +AS VR+ +
Sbjct: 264 NHQNRPQKVVRGRGPRRYEAVAKNNRDVV---GFQRKQPARSRESA--ASASAVRESGQT 318
Query: 465 IAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVRAATFVGEINGV 644
+ NA + N VNS++ AS +G +P+ + D ++A G N V
Sbjct: 319 L--NAQSEMAPPKKNVVNSSLNSASPPFYPSGASNPDFSVPAQRRDNMQA----GGSNKV 372
Query: 645 DPTSV 659
P+S+
Sbjct: 373 FPSSM 377
>UniRef50_O61865 Cluster: Putative uncharacterized protein; n=9;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 488
Score = 34.3 bits (75), Expect = 2.8
Identities = 16/38 (42%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
Frame = -2
Query: 115 FCTARAAGFRARENIFVVC-LTCIYVYI*TIST*PSRP 5
FC+ R F R +F+ C LTC+Y + IST P+ P
Sbjct: 320 FCSKRIKNFGMRPTMFIGCFLTCLYCALVVISTPPTAP 357
>UniRef50_UPI0000DD82B5 Cluster: PREDICTED: hypothetical protein;
n=1; Homo sapiens|Rep: PREDICTED: hypothetical protein -
Homo sapiens
Length = 258
Score = 33.9 bits (74), Expect = 3.7
Identities = 20/41 (48%), Positives = 20/41 (48%), Gaps = 1/41 (2%)
Frame = +2
Query: 218 ESSGDQAGFIRHSACDPRRRSRPFPHE-HPSQGQRPQGT*G 337
E GDQ RH AC R S P E P GQRP GT G
Sbjct: 6 EGRGDQERTRRHRACPGCRGSEVSPGEGAPGSGQRPAGTSG 46
>UniRef50_Q81Y95 Cluster: Serine protease; n=16; Bacillaceae|Rep:
Serine protease - Bacillus anthracis
Length = 413
Score = 33.9 bits (74), Expect = 3.7
Identities = 26/86 (30%), Positives = 38/86 (44%)
Frame = +3
Query: 357 DADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIA 536
D + VI PG + LFN N I+ + IAQ + I I P+N P+
Sbjct: 238 DWNAQVIQTDAAINPGNSGGALFNQNGEIIGINSSKIAQQEVEGIGFAI--PINIAKPVI 295
Query: 537 SEVLKKAGVYDPNRVLGVTTLDVVRA 614
+ K V P +GV +L+ V+A
Sbjct: 296 ESLEKDGVVKRPALGVGVVSLEDVQA 321
>UniRef50_Q608X6 Cluster: Hydrophobe/amphiphile Efflux-1 (HAE1)
family protein; n=17; Proteobacteria|Rep:
Hydrophobe/amphiphile Efflux-1 (HAE1) family protein -
Methylococcus capsulatus
Length = 1054
Score = 33.9 bits (74), Expect = 3.7
Identities = 18/50 (36%), Positives = 28/50 (56%)
Frame = -2
Query: 379 GMTTTSASLMAADSSSGPLWPLTLAGVFMWERSAATPGVTGAMSYKASLV 230
G+T AS+ A +GP+ +TL ++ SA PG+TG M + +LV
Sbjct: 436 GLTPKEASIKAMSEMTGPVIGITLVLTAVFLPSAFLPGITGQMFRQFALV 485
>UniRef50_A6ESK5 Cluster: LysM-repeat protein; n=1; unidentified
eubacterium SCB49|Rep: LysM-repeat protein -
unidentified eubacterium SCB49
Length = 669
Score = 33.9 bits (74), Expect = 3.7
Identities = 18/75 (24%), Positives = 36/75 (48%)
Frame = +3
Query: 384 GVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGV 563
G+ R G+T D+L N + +D+++ N P V N ++ + V +K G
Sbjct: 199 GIARMYGITMDELITMNPGLTKDLSMGSVLNVPSKTVTGSAN-IDDELYSFYTVKQKEGF 257
Query: 564 YDPNRVLGVTTLDVV 608
Y + LG++ +++
Sbjct: 258 YRLEKNLGLSEEEII 272
>UniRef50_A6CMQ6 Cluster: HtrA; n=1; Bacillus sp. SG-1|Rep: HtrA -
Bacillus sp. SG-1
Length = 423
Score = 33.9 bits (74), Expect = 3.7
Identities = 29/111 (26%), Positives = 51/111 (45%), Gaps = 1/111 (0%)
Frame = +3
Query: 282 DLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIAL 461
DLS T VS + + ++++ VI PG + L N+N +V +L
Sbjct: 227 DLSRTVTQGIVSAVDRTISVPTSAGESELNVIQTDAAINPGNSGGALINSNGELVGINSL 286
Query: 462 SIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTL-DVVR 611
I+ + + + I P +PI +E+++ V P +G+T+L DV R
Sbjct: 287 KISTSGVEGLGFAI--PSKDFLPIVNEIIETGKVERPYIGIGMTSLADVPR 335
>UniRef50_Q9VY98 Cluster: CG9941-PA; n=5; Drosophila|Rep: CG9941-PA
- Drosophila melanogaster (Fruit fly)
Length = 789
Score = 33.9 bits (74), Expect = 3.7
Identities = 25/119 (21%), Positives = 46/119 (38%)
Frame = +3
Query: 240 ALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDD 419
AL I V G++ + H NTP +G P ++ ++ G P+ R+
Sbjct: 363 ALLQIRAVQKGISTHVLHQNTPTSAAGEPAPVDVPPGYIPVSLIEALNGPPQYVARARNS 422
Query: 420 LFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTT 596
+ V D A ++A + + T+P+ S+ ++ K A +G T
Sbjct: 423 EHD-----VTDSAATVAASTMTSADIKATSPIKSSSQRRPKIKKNASTCTSTSEVGTIT 476
>UniRef50_Q4S3J0 Cluster: Chromosome 1 SCAF14749, whole genome
shotgun sequence; n=2; Tetraodon nigroviridis|Rep:
Chromosome 1 SCAF14749, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 778
Score = 33.5 bits (73), Expect = 4.9
Identities = 18/47 (38%), Positives = 21/47 (44%)
Frame = +2
Query: 161 GGRWCRRWYRPAFGPSTEAESSGDQAGFIRHSACDPRRRSRPFPHEH 301
G R R + P GP E G Q +RH A P RR R P +H
Sbjct: 554 GVRAPRGLHHPGAGPQRAHEGRGRQPAAVRHPAEPPGRRHRERPGDH 600
>UniRef50_Q3MGZ6 Cluster: Putative uncharacterized protein
precursor; n=1; Anabaena variabilis ATCC 29413|Rep:
Putative uncharacterized protein precursor - Anabaena
variabilis (strain ATCC 29413 / PCC 7937)
Length = 303
Score = 33.5 bits (73), Expect = 4.9
Identities = 18/51 (35%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Frame = +3
Query: 372 VIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAI-ITNPVNS 521
++P G P KP T D+ +T ++ + L +NA KAI+ + NPVN+
Sbjct: 116 LVPEG-PSKPNPTAQDIVSTLGNLNLNSILVTRENADKAIIEVSFANPVNT 165
>UniRef50_A3VG30 Cluster: Putative uncharacterized protein; n=1;
Rhodobacterales bacterium HTCC2654|Rep: Putative
uncharacterized protein - Rhodobacterales bacterium
HTCC2654
Length = 348
Score = 33.5 bits (73), Expect = 4.9
Identities = 25/61 (40%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Frame = +3
Query: 501 ITNPVNSTVPIASEVLKKAGVYDP-NRVLGVTTLDVVRAATFVGEINGVDPTSVAVPRHR 677
IT T PIA+E L +G+ DP NRV+ V TLD V G I D T+ P
Sbjct: 22 ITFTYGKTSPIATEYLP-SGMLDPMNRVILVATLDGVSRVLADGPIKRHDITATRQPGQN 80
Query: 678 R 680
R
Sbjct: 81 R 81
>UniRef50_A0VEV1 Cluster: Putative uncharacterized protein; n=1;
Delftia acidovorans SPH-1|Rep: Putative uncharacterized
protein - Delftia acidovorans SPH-1
Length = 415
Score = 33.5 bits (73), Expect = 4.9
Identities = 16/28 (57%), Positives = 18/28 (64%)
Frame = -1
Query: 668 GHGDGGRVHAIDLADEGGSADYVQSGDA 585
GHG RVHA+DLA AD VQ+G A
Sbjct: 283 GHGAVARVHALDLARHQAVADIVQAGAA 310
>UniRef50_A2XSM8 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. indica (Rice)
Length = 692
Score = 33.5 bits (73), Expect = 4.9
Identities = 33/117 (28%), Positives = 54/117 (46%), Gaps = 5/117 (4%)
Frame = +3
Query: 285 LSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALS 464
L + T + G+KG E +K V+ + PG+TR + + + I I
Sbjct: 88 LQLLETDKEAGGNKGVSEKQIRLKIFSPNVLDITLVDLPGITRVPVGDQPSDIESRIRSM 147
Query: 465 IAQ--NAPKAIVAIITNPVNSTVPIASEVLKKAGVYDP--NRVLGV-TTLDVVRAAT 620
I Q P I+ +T P N+ + S+ L+ A + DP +R +GV T LD++ T
Sbjct: 148 IMQYIKHPSCIILAVT-PANADL-ANSDALQLAKLADPDGSRTIGVITKLDIMDRGT 202
>UniRef50_Q2UFR5 Cluster: Predicted protein; n=2; Aspergillus|Rep:
Predicted protein - Aspergillus oryzae
Length = 299
Score = 33.5 bits (73), Expect = 4.9
Identities = 25/101 (24%), Positives = 41/101 (40%)
Frame = +3
Query: 333 EELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNP 512
+ L+AA++ DVVV GV + N N I IA + + P ++ TNP
Sbjct: 58 KSLTAALQGVDVVVSTVGVAA--------VDNQNVLIDAAIAAGVKRFIPSEFSSVTTNP 109
Query: 513 VNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVRAATFVGEI 635
T+P+ S + K G + V+ F+ +
Sbjct: 110 KLETLPLYSSMFKIRNYLQEKTAAGELSWTVLACGAFLDSV 150
>UniRef50_A2R1L8 Cluster: Contig An13c0060, complete genome; n=2;
Aspergillus|Rep: Contig An13c0060, complete genome -
Aspergillus niger
Length = 332
Score = 33.5 bits (73), Expect = 4.9
Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +3
Query: 198 LALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVI 377
L +L ++ L + +IA + PGVA L ++ ++ +E+ +D DV+V
Sbjct: 51 LIILASRDILKAQQTAQEIANIAPGVATRLLELDLRSQAQVRNAAKEVLTYKEDIDVLVN 110
Query: 378 PAGVPRKP-GMTRDDL 422
AGV P +T D +
Sbjct: 111 NAGVMASPFSLTEDGI 126
>UniRef50_Q4T0R0 Cluster: Chromosome undetermined SCAF10884, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF10884,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 284
Score = 33.1 bits (72), Expect = 6.4
Identities = 18/38 (47%), Positives = 22/38 (57%)
Frame = +2
Query: 551 EGGSVRPEPRARRHHSGRSPRCHLRRRDQWRGPDLRRR 664
EGG VRP+ R H G+ P LRR+ + GP RRR
Sbjct: 171 EGGRVRPQGRELLH--GQRPGLQLRRQPRLPGPQGRRR 206
>UniRef50_Q0SBH8 Cluster: Pyruvate dehydrogenase E1 component; n=7;
Actinobacteria (class)|Rep: Pyruvate dehydrogenase E1
component - Rhodococcus sp. (strain RHA1)
Length = 817
Score = 33.1 bits (72), Expect = 6.4
Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 2/68 (2%)
Frame = +3
Query: 378 PAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIIT-NP-VNSTVPIASEVLK 551
P VP G T T A++ R + L +++ AP A ++T +P V+ST +A L
Sbjct: 439 PPAVPADIGRTPSGTSTTQAALGRAL-LDLSREAPDAAKRVVTVSPDVSSTTNLAGW-LN 496
Query: 552 KAGVYDPN 575
K GV+ PN
Sbjct: 497 KVGVWSPN 504
>UniRef50_UPI0000D9F76A Cluster: PREDICTED: hypothetical protein,
partial; n=2; Macaca mulatta|Rep: PREDICTED:
hypothetical protein, partial - Macaca mulatta
Length = 517
Score = 32.7 bits (71), Expect = 8.5
Identities = 24/110 (21%), Positives = 43/110 (39%), Gaps = 1/110 (0%)
Frame = +3
Query: 222 PLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKP 401
P+ + + A PG D + TP +SA+++ ++ P + P
Sbjct: 183 PVTGEVTITTAAGEVPGRDKDDADATTPIATETATVATTISASVEPTTIMTSPQPLGEAP 242
Query: 402 GMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNP-VNSTVPIASEVL 548
G +DD + + + A + +AP IT P ST + EV+
Sbjct: 243 GRDKDD-SDATTPVATETATATTIDAPVEPTTTITTPQPASTAAVTDEVV 291
>UniRef50_Q91LF0 Cluster: ORF90; n=1; Shrimp white spot syndrome
virus|Rep: ORF90 - White spot syndrome virus (WSSV)
Length = 759
Score = 32.7 bits (71), Expect = 8.5
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
Frame = +3
Query: 246 YDIAPVTPG--VAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPA-GVPRKPGMTRD 416
+D+ P TPG V + K +G +G EE ++ + + P PR PG RD
Sbjct: 664 FDLPPATPGRNVEEIIKAQRQAVKETGVRGEEE-----EEEEAFIAPIIRQPRTPGNFRD 718
Query: 417 DLFNTNASI 443
+L + N SI
Sbjct: 719 ELLDVNESI 727
>UniRef50_Q9XVM1 Cluster: Putative uncharacterized protein tag-65;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein tag-65 - Caenorhabditis elegans
Length = 675
Score = 32.7 bits (71), Expect = 8.5
Identities = 17/40 (42%), Positives = 22/40 (55%)
Frame = +2
Query: 560 SVRPEPRARRHHSGRSPRCHLRRRDQWRGPDLRRRAPSSA 679
++R + ARR +S PR H R R R P RRR SS+
Sbjct: 509 NLREDSEARRSNSRSPPRDHKRSRSPSRSPSPRRRQRSSS 548
>UniRef50_A7SI71 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 1647
Score = 32.7 bits (71), Expect = 8.5
Identities = 23/57 (40%), Positives = 34/57 (59%), Gaps = 1/57 (1%)
Frame = -2
Query: 394 RGTPAGMTTTSASLMAADSSSGPLWPLTLAGVFMWERSAATPGVTGAMS-YKASLVT 227
RG P+GM+TT++S ++D S L +T G + S+ TPG GA++ SLVT
Sbjct: 931 RGLPSGMSTTNSSTQSSDPS--VLGSVTSVGNLV--TSSLTPGFLGALAELVRSLVT 983
>UniRef50_Q8NHM5 Cluster: JmjC domain-containing histone
demethylation protein 1B; n=56; Euteleostomi|Rep: JmjC
domain-containing histone demethylation protein 1B -
Homo sapiens (Human)
Length = 1336
Score = 32.7 bits (71), Expect = 8.5
Identities = 14/22 (63%), Positives = 16/22 (72%)
Frame = -3
Query: 168 RPPL*SSSVMWWKSSLHHFVQQ 103
RPPL SS WW+SSL +F QQ
Sbjct: 834 RPPLGSSLSPWWRSSLTYFQQQ 855
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 758,374,471
Number of Sequences: 1657284
Number of extensions: 17395396
Number of successful extensions: 60359
Number of sequences better than 10.0: 179
Number of HSP's better than 10.0 without gapping: 56118
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 60218
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 52892566912
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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