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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Nnor0459
         (484 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC126356-1|AAI26357.1| 1115|Homo sapiens eukaryotic translation ...    45   1e-04
BC126354-1|AAI26355.1| 1116|Homo sapiens eukaryotic translation ...    45   1e-04
AF284615-1|AAF91480.1| 1115|Homo sapiens initiation factor 2-alp...    45   1e-04
AF193339-1|AAF61199.1| 1115|Homo sapiens eukaryotic translation ...    45   1e-04
AF110146-1|AAD19961.1| 1115|Homo sapiens eukaryotic translation ...    45   1e-04
AC104134-2|AAY24331.1|  970|Homo sapiens unknown protein.              45   1e-04
BC006524-1|AAH06524.1|  630|Homo sapiens eukaryotic translation ...    41   0.002
AF255050-1|AAF70289.1|  629|Homo sapiens heme-regulated eukaryot...    41   0.002
AF183414-1|AAG09683.1|  630|Homo sapiens hemin-sensitive initiat...    41   0.002
AF181071-1|AAF18391.1|  630|Homo sapiens heme-regulated initiati...    41   0.002
AF147094-1|AAF66736.1|  629|Homo sapiens heme-regulated initiati...    41   0.002
AF100784-1|AAP97223.1|  630|Homo sapiens hemin-sensitive initita...    41   0.002
AC005995-1|AAS00388.1|  386|Homo sapiens unknown protein.              41   0.002
AB037790-1|BAA92607.1|  653|Homo sapiens KIAA1369 protein protein.     41   0.002
AK075192-1|BAC11461.1|  630|Homo sapiens protein ( Homo sapiens ...    41   0.003
AF053754-1|AAF21719.1| 1079|Homo sapiens electrogenic Na+ bicarb...    30   3.7  
DQ092367-1|AAY96755.1|  172|Homo sapiens cellular nucleic acid b...    29   8.6  
AF310248-1|AAG47773.1| 1079|Homo sapiens sodium bicarbonate cotr...    29   8.6  
AF157492-1|AAF80343.1|  995|Homo sapiens sodium bicarbonate cotr...    29   8.6  
AF069510-1|AAD42020.1| 1079|Homo sapiens sodium bicarbonate cotr...    29   8.6  
AF053753-1|AAF21718.1| 1079|Homo sapiens electrogenic Na+ bicarb...    29   8.6  
AF011390-1|AAC39840.1| 1079|Homo sapiens pancreas sodium bicarbo...    29   8.6  
AF007216-1|AAC51645.1| 1035|Homo sapiens sodium bicarbonate cotr...    29   8.6  
AB209119-1|BAD92356.1| 1780|Homo sapiens eukaryotic translation ...    29   8.6  

>BC126356-1|AAI26357.1| 1115|Homo sapiens eukaryotic translation
            initiation factor 2-alpha kinase 3 protein.
          Length = 1115

 Score = 45.2 bits (102), Expect = 1e-04
 Identities = 23/50 (46%), Positives = 28/50 (56%)
 Frame = -3

Query: 476  YSYKVDIYSXXXXXXXXLQPFGTEAERAACLTRVRDQVYPDSFEDKYPKE 327
            YS+KVDI+S        L PF T+ ER   LT VR+  +P  F  KYP E
Sbjct: 1000 YSHKVDIFSLGLILFELLYPFSTQMERVRTLTDVRNLKFPPLFTQKYPCE 1049


>BC126354-1|AAI26355.1| 1116|Homo sapiens eukaryotic translation
            initiation factor 2-alpha kinase 3 protein.
          Length = 1116

 Score = 45.2 bits (102), Expect = 1e-04
 Identities = 23/50 (46%), Positives = 28/50 (56%)
 Frame = -3

Query: 476  YSYKVDIYSXXXXXXXXLQPFGTEAERAACLTRVRDQVYPDSFEDKYPKE 327
            YS+KVDI+S        L PF T+ ER   LT VR+  +P  F  KYP E
Sbjct: 1001 YSHKVDIFSLGLILFELLYPFSTQMERVRTLTDVRNLKFPPLFTQKYPCE 1050


>AF284615-1|AAF91480.1| 1115|Homo sapiens initiation factor 2-alpha
            kinase 3 protein.
          Length = 1115

 Score = 45.2 bits (102), Expect = 1e-04
 Identities = 23/50 (46%), Positives = 28/50 (56%)
 Frame = -3

Query: 476  YSYKVDIYSXXXXXXXXLQPFGTEAERAACLTRVRDQVYPDSFEDKYPKE 327
            YS+KVDI+S        L PF T+ ER   LT VR+  +P  F  KYP E
Sbjct: 1000 YSHKVDIFSLGLILFELLYPFSTQMERVRTLTDVRNLKFPPLFTQKYPCE 1049


>AF193339-1|AAF61199.1| 1115|Homo sapiens eukaryotic translation
            initiation factor 2 alpha kinase PEK protein.
          Length = 1115

 Score = 45.2 bits (102), Expect = 1e-04
 Identities = 23/50 (46%), Positives = 28/50 (56%)
 Frame = -3

Query: 476  YSYKVDIYSXXXXXXXXLQPFGTEAERAACLTRVRDQVYPDSFEDKYPKE 327
            YS+KVDI+S        L PF T+ ER   LT VR+  +P  F  KYP E
Sbjct: 1000 YSHKVDIFSLGLILFELLYPFSTQMERVRTLTDVRNLKFPPLFTQKYPCE 1049


>AF110146-1|AAD19961.1| 1115|Homo sapiens eukaryotic translation
            initiation factor 2 alpha kinase PEK protein.
          Length = 1115

 Score = 45.2 bits (102), Expect = 1e-04
 Identities = 23/50 (46%), Positives = 28/50 (56%)
 Frame = -3

Query: 476  YSYKVDIYSXXXXXXXXLQPFGTEAERAACLTRVRDQVYPDSFEDKYPKE 327
            YS+KVDI+S        L PF T+ ER   LT VR+  +P  F  KYP E
Sbjct: 1000 YSHKVDIFSLGLILFELLYPFSTQMERVRTLTDVRNLKFPPLFTQKYPCE 1049


>AC104134-2|AAY24331.1|  970|Homo sapiens unknown protein.
          Length = 970

 Score = 45.2 bits (102), Expect = 1e-04
 Identities = 23/50 (46%), Positives = 28/50 (56%)
 Frame = -3

Query: 476  YSYKVDIYSXXXXXXXXLQPFGTEAERAACLTRVRDQVYPDSFEDKYPKE 327
            YS+KVDI+S        L PF T+ ER   LT VR+  +P  F  KYP E
Sbjct: 855  YSHKVDIFSLGLILFELLYPFSTQMERVRTLTDVRNLKFPPLFTQKYPCE 904


>BC006524-1|AAH06524.1|  630|Homo sapiens eukaryotic translation
           initiation factor 2-alpha kinase 1 protein.
          Length = 630

 Score = 41.1 bits (92), Expect = 0.002
 Identities = 20/54 (37%), Positives = 28/54 (51%)
 Frame = -3

Query: 476 YSYKVDIYSXXXXXXXXLQPFGTEAERAACLTRVRDQVYPDSFEDKYPKEMEHL 315
           Y  K D+YS         QPFGTE ERA  LT +R    P+S   + P + +++
Sbjct: 507 YDAKSDMYSLGVVLLELFQPFGTEMERAEVLTGLRTGQLPESLRKRCPVQAKYI 560


>AF255050-1|AAF70289.1|  629|Homo sapiens heme-regulated eukaryotic
           initiation factor 2 alpha kinase protein.
          Length = 629

 Score = 41.1 bits (92), Expect = 0.002
 Identities = 20/54 (37%), Positives = 28/54 (51%)
 Frame = -3

Query: 476 YSYKVDIYSXXXXXXXXLQPFGTEAERAACLTRVRDQVYPDSFEDKYPKEMEHL 315
           Y  K D+YS         QPFGTE ERA  LT +R    P+S   + P + +++
Sbjct: 506 YDAKSDMYSLGVVLLELFQPFGTEMERAEVLTGLRTGQLPESLRKRCPVQAKYI 559


>AF183414-1|AAG09683.1|  630|Homo sapiens hemin-sensitive initiation
           factor 2a kinase protein.
          Length = 630

 Score = 41.1 bits (92), Expect = 0.002
 Identities = 20/54 (37%), Positives = 28/54 (51%)
 Frame = -3

Query: 476 YSYKVDIYSXXXXXXXXLQPFGTEAERAACLTRVRDQVYPDSFEDKYPKEMEHL 315
           Y  K D+YS         QPFGTE ERA  LT +R    P+S   + P + +++
Sbjct: 507 YDAKSDMYSLGVVLLELFQPFGTEMERAEVLTGLRTGQLPESLRKRCPVQAKYI 560


>AF181071-1|AAF18391.1|  630|Homo sapiens heme-regulated initiation
           factor 2-alpha kinase protein.
          Length = 630

 Score = 41.1 bits (92), Expect = 0.002
 Identities = 20/54 (37%), Positives = 28/54 (51%)
 Frame = -3

Query: 476 YSYKVDIYSXXXXXXXXLQPFGTEAERAACLTRVRDQVYPDSFEDKYPKEMEHL 315
           Y  K D+YS         QPFGTE ERA  LT +R    P+S   + P + +++
Sbjct: 507 YDAKSDMYSLGVVLLELFQPFGTEMERAEVLTGLRTGQLPESLRKRCPVQAKYI 560


>AF147094-1|AAF66736.1|  629|Homo sapiens heme-regulated initiation
           factor 2 alpha kinase protein.
          Length = 629

 Score = 41.1 bits (92), Expect = 0.002
 Identities = 20/54 (37%), Positives = 28/54 (51%)
 Frame = -3

Query: 476 YSYKVDIYSXXXXXXXXLQPFGTEAERAACLTRVRDQVYPDSFEDKYPKEMEHL 315
           Y  K D+YS         QPFGTE ERA  LT +R    P+S   + P + +++
Sbjct: 506 YDAKSDMYSLGVVLLELFQPFGTEMERAEVLTGLRTGQLPESLRKRCPVQAKYI 559


>AF100784-1|AAP97223.1|  630|Homo sapiens hemin-sensitive
           inititation factor 2a kinase protein.
          Length = 630

 Score = 41.1 bits (92), Expect = 0.002
 Identities = 20/54 (37%), Positives = 28/54 (51%)
 Frame = -3

Query: 476 YSYKVDIYSXXXXXXXXLQPFGTEAERAACLTRVRDQVYPDSFEDKYPKEMEHL 315
           Y  K D+YS         QPFGTE ERA  LT +R    P+S   + P + +++
Sbjct: 507 YDAKSDMYSLGVVLLELFQPFGTEMERAEVLTGLRTGQLPESLRKRCPVQAKYI 560


>AC005995-1|AAS00388.1|  386|Homo sapiens unknown protein.
          Length = 386

 Score = 41.1 bits (92), Expect = 0.002
 Identities = 20/54 (37%), Positives = 28/54 (51%)
 Frame = -3

Query: 476 YSYKVDIYSXXXXXXXXLQPFGTEAERAACLTRVRDQVYPDSFEDKYPKEMEHL 315
           Y  K D+YS         QPFGTE ERA  LT +R    P+S   + P + +++
Sbjct: 263 YDAKSDMYSLGVVLLELFQPFGTEMERAEVLTGLRTGQLPESLRKRCPVQAKYI 316


>AB037790-1|BAA92607.1|  653|Homo sapiens KIAA1369 protein protein.
          Length = 653

 Score = 41.1 bits (92), Expect = 0.002
 Identities = 20/54 (37%), Positives = 28/54 (51%)
 Frame = -3

Query: 476 YSYKVDIYSXXXXXXXXLQPFGTEAERAACLTRVRDQVYPDSFEDKYPKEMEHL 315
           Y  K D+YS         QPFGTE ERA  LT +R    P+S   + P + +++
Sbjct: 530 YDAKSDMYSLGVVLLELFQPFGTEMERAEVLTGLRTGQLPESLRKRCPVQAKYI 583


>AK075192-1|BAC11461.1|  630|Homo sapiens protein ( Homo sapiens
           cDNA FLJ90711 fis, clone PLACE1008282, highly similar to
           HEME-REGULATED EUKARYOTIC INITIATION FACTOR EIF-2-ALPHA
           KINASE ).
          Length = 630

 Score = 40.7 bits (91), Expect = 0.003
 Identities = 20/54 (37%), Positives = 27/54 (50%)
 Frame = -3

Query: 476 YSYKVDIYSXXXXXXXXLQPFGTEAERAACLTRVRDQVYPDSFEDKYPKEMEHL 315
           Y  K D+YS         QPFGTE ERA  LT +R    P+S   + P +  ++
Sbjct: 507 YDAKSDMYSLGVVLLELFQPFGTEMERAEVLTGLRTGQLPESLRKRCPVQARYI 560


>AF053754-1|AAF21719.1| 1079|Homo sapiens electrogenic Na+ bicarbonate
            cotransporter form 2 protein.
          Length = 1079

 Score = 30.3 bits (65), Expect = 3.7
 Identities = 20/54 (37%), Positives = 30/54 (55%), Gaps = 3/54 (5%)
 Frame = +1

Query: 100  KKRRKKKEDVEGDSEESAAVRDSKLDSIISE*DAVKYLPFKLSD---YDRFYPP 252
            KK++KKK  ++ D+++S      K+ SI    D ++  PF LSD    DR  PP
Sbjct: 1018 KKKKKKKGSLDSDNDDSDCPYSEKVPSIKIPMDIMEQQPF-LSDSKPSDRERPP 1070


>DQ092367-1|AAY96755.1|  172|Homo sapiens cellular nucleic acid
           binding protein beta variant 2 protein.
          Length = 172

 Score = 29.1 bits (62), Expect = 8.6
 Identities = 12/22 (54%), Positives = 15/22 (68%)
 Frame = +1

Query: 253 VKQCLRCLR*GHIAKFCKKAER 318
           V+ C  C R GHIAK CK+ +R
Sbjct: 66  VEACYNCGRGGHIAKDCKEPKR 87


>AF310248-1|AAG47773.1| 1079|Homo sapiens sodium bicarbonate
            cotransporter protein.
          Length = 1079

 Score = 29.1 bits (62), Expect = 8.6
 Identities = 16/44 (36%), Positives = 26/44 (59%)
 Frame = +1

Query: 100  KKRRKKKEDVEGDSEESAAVRDSKLDSIISE*DAVKYLPFKLSD 231
            KK++KKK  ++ D+++S      K+ SI    D ++  PF LSD
Sbjct: 1018 KKKKKKKGSLDSDNDDSDCPYSEKVPSIKIPMDIMEQQPF-LSD 1060


>AF157492-1|AAF80343.1|  995|Homo sapiens sodium bicarbonate
            cotransporter NBC1 protein.
          Length = 995

 Score = 29.1 bits (62), Expect = 8.6
 Identities = 16/44 (36%), Positives = 26/44 (59%)
 Frame = +1

Query: 100  KKRRKKKEDVEGDSEESAAVRDSKLDSIISE*DAVKYLPFKLSD 231
            KK++KKK  ++ D+++S      K+ SI    D ++  PF LSD
Sbjct: 934  KKKKKKKGSLDSDNDDSDCPYSEKVPSIKIPMDIMEQQPF-LSD 976


>AF069510-1|AAD42020.1| 1079|Homo sapiens sodium bicarbonate
            cotransporter protein.
          Length = 1079

 Score = 29.1 bits (62), Expect = 8.6
 Identities = 16/44 (36%), Positives = 26/44 (59%)
 Frame = +1

Query: 100  KKRRKKKEDVEGDSEESAAVRDSKLDSIISE*DAVKYLPFKLSD 231
            KK++KKK  ++ D+++S      K+ SI    D ++  PF LSD
Sbjct: 1018 KKKKKKKGSLDSDNDDSDCPYSEKVPSIKIPMDIMEQQPF-LSD 1060


>AF053753-1|AAF21718.1| 1079|Homo sapiens electrogenic Na+ bicarbonate
            cotransporter protein.
          Length = 1079

 Score = 29.1 bits (62), Expect = 8.6
 Identities = 16/44 (36%), Positives = 26/44 (59%)
 Frame = +1

Query: 100  KKRRKKKEDVEGDSEESAAVRDSKLDSIISE*DAVKYLPFKLSD 231
            KK++KKK  ++ D+++S      K+ SI    D ++  PF LSD
Sbjct: 1018 KKKKKKKGSLDSDNDDSDCPYSEKVPSIKIPMDIMEQQPF-LSD 1060


>AF011390-1|AAC39840.1| 1079|Homo sapiens pancreas sodium bicarbonate
            cotransporter protein.
          Length = 1079

 Score = 29.1 bits (62), Expect = 8.6
 Identities = 16/44 (36%), Positives = 26/44 (59%)
 Frame = +1

Query: 100  KKRRKKKEDVEGDSEESAAVRDSKLDSIISE*DAVKYLPFKLSD 231
            KK++KKK  ++ D+++S      K+ SI    D ++  PF LSD
Sbjct: 1018 KKKKKKKGSLDSDNDDSDCPYSEKVPSIKIPMDIMEQQPF-LSD 1060


>AF007216-1|AAC51645.1| 1035|Homo sapiens sodium bicarbonate
            cotransporter protein.
          Length = 1035

 Score = 29.1 bits (62), Expect = 8.6
 Identities = 16/44 (36%), Positives = 26/44 (59%)
 Frame = +1

Query: 100  KKRRKKKEDVEGDSEESAAVRDSKLDSIISE*DAVKYLPFKLSD 231
            KK++KKK  ++ D+++S      K+ SI    D ++  PF LSD
Sbjct: 974  KKKKKKKGSLDSDNDDSDCPYSEKVPSIKIPMDIMEQQPF-LSD 1016


>AB209119-1|BAD92356.1| 1780|Homo sapiens eukaryotic translation
           initiation factor 4 gamma, 3 variant protein.
          Length = 1780

 Score = 29.1 bits (62), Expect = 8.6
 Identities = 10/22 (45%), Positives = 13/22 (59%)
 Frame = -1

Query: 175 PTSSPAPQRFPRSLPRHLPFSY 110
           PTS+P P + P  +P H P  Y
Sbjct: 370 PTSTPTPPQLPSQVPEHSPVVY 391


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 58,631,282
Number of Sequences: 237096
Number of extensions: 1054274
Number of successful extensions: 3497
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 3187
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3473
length of database: 76,859,062
effective HSP length: 84
effective length of database: 56,942,998
effective search space used: 4327667848
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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