Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Nnor0341
(545 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_A2QMH9 Cluster: Malate dehydrogenase; n=7; Fungi/Metazo... 93 4e-18
UniRef50_Q9SN86 Cluster: Malate dehydrogenase, chloroplast precu... 93 4e-18
UniRef50_A7SQS1 Cluster: Predicted protein; n=1; Nematostella ve... 93 5e-18
UniRef50_Q42972 Cluster: Malate dehydrogenase, glyoxysomal precu... 91 2e-17
UniRef50_P08249 Cluster: Malate dehydrogenase, mitochondrial pre... 91 2e-17
UniRef50_P40926 Cluster: Malate dehydrogenase, mitochondrial pre... 90 3e-17
UniRef50_Q9Y7R8 Cluster: Malate dehydrogenase; n=13; Dikarya|Rep... 88 1e-16
UniRef50_Q6BM17 Cluster: Malate dehydrogenase; n=4; Eukaryota|Re... 88 1e-16
UniRef50_Q4QDF0 Cluster: Glycosomal malate dehydrogenase; n=9; T... 81 2e-14
UniRef50_Q4Q3J3 Cluster: Malate dehydrogenase, putative; n=3; Le... 78 1e-13
UniRef50_P32419 Cluster: Malate dehydrogenase, peroxisomal; n=24... 77 3e-13
UniRef50_Q6FL22 Cluster: Malate dehydrogenase; n=1; Candida glab... 75 8e-13
UniRef50_P22133 Cluster: Malate dehydrogenase, cytoplasmic; n=3;... 75 1e-12
UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep: A... 73 3e-12
UniRef50_A7TSF5 Cluster: Putative uncharacterized protein; n=1; ... 73 4e-12
UniRef50_Q5ENS5 Cluster: Malate dehydrogenase; n=1; Heterocapsa ... 71 2e-11
UniRef50_UPI00005A0834 Cluster: PREDICTED: similar to Malate deh... 71 2e-11
UniRef50_Q9VU29 Cluster: Malate dehydrogenase; n=5; Protostomia|... 70 3e-11
UniRef50_A3BMG8 Cluster: Putative uncharacterized protein; n=3; ... 70 4e-11
UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3; Acti... 69 9e-11
UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces cere... 66 7e-10
UniRef50_A7TL95 Cluster: Putative uncharacterized protein; n=1; ... 65 1e-09
UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular o... 64 2e-09
UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Re... 64 3e-09
UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2... 63 4e-09
UniRef50_Q9VU28 Cluster: Malate dehydrogenase; n=3; Sophophora|R... 63 5e-09
UniRef50_Q64P62 Cluster: Malate dehydrogenase; n=28; Bacteroidet... 63 5e-09
UniRef50_Q017A6 Cluster: Malate dehydrogenase; n=2; cellular org... 61 1e-08
UniRef50_Q8TWG5 Cluster: Malate dehydrogenase; n=2; Euryarchaeot... 61 1e-08
UniRef50_Q3J7E7 Cluster: Malate dehydrogenase; n=5; Gammaproteob... 61 2e-08
UniRef50_O08349 Cluster: Malate dehydrogenase; n=1; Archaeoglobu... 60 3e-08
UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD bindi... 59 6e-08
UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|R... 59 6e-08
UniRef50_Q8ZVB2 Cluster: Malate dehydrogenase; n=14; Thermoprote... 59 6e-08
UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|R... 59 6e-08
UniRef50_P16115 Cluster: L-lactate dehydrogenase; n=4; Thermotog... 59 8e-08
UniRef50_Q86DP2 Cluster: Malate dehydrogenase; n=11; Fungi/Metaz... 58 1e-07
UniRef50_Q979N9 Cluster: Malate dehydrogenase; n=4; Thermoplasma... 58 1e-07
UniRef50_A6Q7S2 Cluster: Malate dehydrogenase, NAD-dependent; n=... 57 2e-07
UniRef50_A7I2F1 Cluster: Malate dehydrogenase; n=1; Campylobacte... 57 3e-07
UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;... 56 4e-07
UniRef50_A3EWH3 Cluster: Malate/lactate dehydrogenase; n=1; Lept... 56 4e-07
UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter... 56 7e-07
UniRef50_Q18WQ6 Cluster: Malate dehydrogenase, NAD-dependent; n=... 55 1e-06
UniRef50_P11386 Cluster: Malate dehydrogenase; n=6; Sulfolobacea... 55 1e-06
UniRef50_A4BB89 Cluster: Lactate dehydrogenase; n=2; Gammaproteo... 54 2e-06
UniRef50_Q7NHJ3 Cluster: Malate dehydrogenase; n=13; cellular or... 54 2e-06
UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1; ... 54 3e-06
UniRef50_A4L2P0 Cluster: L-lactate dehydrogenase; n=4; Lactobaci... 54 3e-06
UniRef50_A0RPE9 Cluster: Malate dehydrogenase; n=1; Campylobacte... 53 4e-06
UniRef50_Q7M9A7 Cluster: Malate dehydrogenase; n=4; Epsilonprote... 53 5e-06
UniRef50_O26290 Cluster: Malate dehydrogenase; n=2; Methanobacte... 52 7e-06
UniRef50_A0RXX8 Cluster: Malate/L-lactate dehydrogenase; n=1; Ce... 52 9e-06
UniRef50_Q3ZZJ7 Cluster: Malate dehydrogenase; n=5; cellular org... 51 2e-05
UniRef50_Q892U0 Cluster: L-lactate dehydrogenase; n=12; Bacteria... 51 2e-05
UniRef50_Q6A9C3 Cluster: L-lactate dehydrogenase; n=2; Propionib... 51 2e-05
UniRef50_Q8XP62 Cluster: L-lactate dehydrogenase; n=11; Clostrid... 51 2e-05
UniRef50_P59390 Cluster: L-lactate dehydrogenase 2; n=8; Lactoba... 51 2e-05
UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;... 50 4e-05
UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3; Methanomi... 50 4e-05
UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasm... 50 4e-05
UniRef50_Q81K80 Cluster: L-lactate dehydrogenase 2; n=12; Firmic... 50 4e-05
UniRef50_P50933 Cluster: L-lactate dehydrogenase; n=7; Bacteria|... 50 5e-05
UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex ae... 49 8e-05
UniRef50_Q7UY63 Cluster: L-lactate/malate dehydrogenase; n=2; Pl... 48 1e-04
UniRef50_Q07841 Cluster: Malate dehydrogenase; n=7; Halobacteria... 48 1e-04
UniRef50_A2SNY0 Cluster: Malate/lactate dehydrogenases-like prot... 48 1e-04
UniRef50_A1HSK3 Cluster: Lactate/malate dehydrogenase; n=1; Ther... 48 1e-04
UniRef50_A7DRG3 Cluster: Lactate/malate dehydrogenase; n=1; Cand... 48 1e-04
UniRef50_Q6KIP9 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm... 48 1e-04
UniRef50_Q838C9 Cluster: L-lactate dehydrogenase 2; n=9; Bacilli... 48 1e-04
UniRef50_Q1FID3 Cluster: L-lactate dehydrogenase precursor; n=1;... 48 2e-04
UniRef50_A3DCA4 Cluster: L-lactate dehydrogenase precursor; n=2;... 48 2e-04
UniRef50_P19869 Cluster: L-lactate dehydrogenase 2; n=17; Bacter... 48 2e-04
UniRef50_P0A3M9 Cluster: L-lactate dehydrogenase; n=140; Bacteri... 47 2e-04
UniRef50_A3JXA9 Cluster: L-lactate dehydrogenase; n=1; Sagittula... 46 6e-04
UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=... 46 6e-04
UniRef50_O51114 Cluster: L-lactate dehydrogenase; n=4; Borrelia ... 46 6e-04
UniRef50_Q98PG4 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm... 46 8e-04
UniRef50_P62051 Cluster: L-lactate dehydrogenase; n=2; Desulfovi... 46 8e-04
UniRef50_A5KJY5 Cluster: Putative uncharacterized protein; n=2; ... 45 0.001
UniRef50_UPI0000DB76D8 Cluster: PREDICTED: similar to CG7998-PA;... 45 0.001
UniRef50_UPI0000D571DB Cluster: PREDICTED: similar to CG7998-PA;... 45 0.001
UniRef50_UPI0000D55CD8 Cluster: PREDICTED: similar to Malate DeH... 44 0.002
UniRef50_Q87JV1 Cluster: Lactate dehydrogenase; n=4; Vibrio|Rep:... 44 0.002
UniRef50_Q6F0L9 Cluster: L-lactate dehydrogenase; n=6; Mollicute... 44 0.002
UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2; ... 44 0.002
UniRef50_UPI000038D9FF Cluster: COG0039: Malate/lactate dehydrog... 44 0.003
UniRef50_Q03BE6 Cluster: L-lactate dehydrogenase; n=1; Lactobaci... 44 0.003
UniRef50_Q8I8U4 Cluster: Lactate dehydrogenase; n=3; Eimeriorina... 44 0.003
UniRef50_Q27743 Cluster: L-lactate dehydrogenase; n=17; Apicompl... 44 0.003
UniRef50_A6M0Q2 Cluster: L-lactate dehydrogenase; n=1; Clostridi... 43 0.005
UniRef50_Q23CW4 Cluster: Malate dehydrogenase, cytoplasmic, puta... 43 0.005
UniRef50_UPI00015B5ACF Cluster: PREDICTED: similar to ENSANGP000... 42 0.009
UniRef50_Q2S4R2 Cluster: L-lactate dehydrogenase; n=1; Salinibac... 42 0.012
UniRef50_UPI0000D56DC5 Cluster: PREDICTED: similar to Malate deh... 41 0.016
UniRef50_Q9EVR0 Cluster: L-lactate dehydrogenase; n=1; Selenomon... 41 0.016
UniRef50_Q4Q3J5 Cluster: Malate dehydrogenase, putative; n=5; Tr... 41 0.021
UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4; Bacteroidale... 40 0.028
UniRef50_A1U9V0 Cluster: Lactate/malate dehydrogenase; n=6; Acti... 40 0.028
UniRef50_Q6JH30 Cluster: Lactate dehydrogenase; n=3; Plasmodium ... 40 0.038
UniRef50_Q9PHY2 Cluster: Probable malate dehydrogenase; n=12; Ca... 39 0.066
UniRef50_Q1IRL5 Cluster: L-lactate dehydrogenase; n=6; Bacteria|... 39 0.087
UniRef50_A4A2L6 Cluster: L-lactate dehydrogenase; n=4; Bacteria|... 39 0.087
UniRef50_Q4UJ29 Cluster: L-lactate dehydrogenase, putative; n=2;... 39 0.087
UniRef50_P20619 Cluster: L-lactate dehydrogenase X; n=14; Bacill... 38 0.11
UniRef50_A2UB98 Cluster: Lactate/malate dehydrogenase precursor;... 38 0.15
UniRef50_A0D8T3 Cluster: Malate dehydrogenase; n=2; Paramecium t... 38 0.20
UniRef50_Q4JY42 Cluster: L-lactate dehydrogenase; n=1; Corynebac... 38 0.20
UniRef50_Q9P4B6 Cluster: L-lactate dehydrogenase A; n=48; Rhizop... 37 0.26
UniRef50_Q81XJ7 Cluster: L-lactate dehydrogenase 3; n=13; Firmic... 37 0.26
UniRef50_Q017A7 Cluster: Chromosome 06 contig 1, DNA sequence; n... 36 0.46
UniRef50_P61973 Cluster: Malate dehydrogenase; n=43; Bacteria|Re... 36 0.46
UniRef50_UPI0001554DCB Cluster: PREDICTED: similar to Zinc finge... 36 0.81
UniRef50_Q0UX88 Cluster: L-lactate dehydrogenase; n=2; Phaeospha... 35 1.1
UniRef50_A2QJT7 Cluster: Catalytic activity: precursor; n=1; Asp... 35 1.1
UniRef50_Q0PQR8 Cluster: Malate dehydrogenase NAD-dependent; n=1... 35 1.4
UniRef50_O61865 Cluster: Putative uncharacterized protein; n=9; ... 34 1.9
UniRef50_A3CTN0 Cluster: Lactate/malate dehydrogenase; n=1; Meth... 34 1.9
UniRef50_Q97DC6 Cluster: L-lactate dehydrogenase 2; n=1; Clostri... 34 1.9
UniRef50_UPI0000DD82B5 Cluster: PREDICTED: hypothetical protein;... 34 2.5
UniRef50_Q4S3J0 Cluster: Chromosome 1 SCAF14749, whole genome sh... 33 3.3
UniRef50_Q64YY6 Cluster: Malate dehydrogenase; n=5; Bacteroidale... 33 3.3
UniRef50_Q9GPV2 Cluster: Cytosolic malate dehydrogenase; n=4; Tr... 33 4.3
UniRef50_UPI00015B4591 Cluster: PREDICTED: similar to mitochondr... 33 5.7
UniRef50_Q8NHM5 Cluster: JmjC domain-containing histone demethyl... 33 5.7
UniRef50_UPI0000DD849E Cluster: PREDICTED: hypothetical protein;... 32 7.5
UniRef50_Q6ABA1 Cluster: DNA polymerase III subunit gamma; n=2; ... 32 7.5
UniRef50_P83778 Cluster: Malate dehydrogenase, cytoplasmic; n=1;... 32 7.5
UniRef50_UPI000023EEAF Cluster: hypothetical protein FG02077.1; ... 32 9.9
UniRef50_Q3MGZ6 Cluster: Putative uncharacterized protein precur... 32 9.9
UniRef50_A5CM82 Cluster: Putative uncharacterized protein; n=1; ... 32 9.9
UniRef50_Q47706 Cluster: Membrane-associated protein uidC precur... 32 9.9
UniRef50_P55735 Cluster: Protein SEC13 homolog; n=84; Eukaryota|... 32 9.9
UniRef50_Q9Z6N1 Cluster: Malate dehydrogenase; n=8; Chlamydiacea... 32 9.9
UniRef50_A1W9K7 Cluster: Malate dehydrogenase; n=95; cellular or... 32 9.9
>UniRef50_A2QMH9 Cluster: Malate dehydrogenase; n=7; Fungi/Metazoa
group|Rep: Malate dehydrogenase - Aspergillus niger
Length = 340
Score = 93.1 bits (221), Expect = 4e-18
Identities = 43/62 (69%), Positives = 54/62 (87%)
Frame = +1
Query: 358 ADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNSTVPIDS 537
+++++IPAGVPRKPGMTRDDLFNTNA IVRD+A + A AP+A + +I+NPVNSTVPI S
Sbjct: 93 SEIILIPAGVPRKPGMTRDDLFNTNASIVRDLAKAAAEAAPEANILVISNPVNSTVPIVS 152
Query: 538 EV 543
EV
Sbjct: 153 EV 154
Score = 70.1 bits (164), Expect = 3e-11
Identities = 39/79 (49%), Positives = 52/79 (65%), Gaps = 1/79 (1%)
Frame = +2
Query: 122 KNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNT 301
++FS ++ + K IGQPL+LL+KQNPLVT LALYDI PGVAAD+SH+NT
Sbjct: 14 RSFSASASQASKVAVLGAAGGIGQPLSLLMKQNPLVTDLALYDIRG-GPGVAADISHINT 72
Query: 302 PAKVSGHK-GPEELSAAIK 355
+ V G++ P L A+K
Sbjct: 73 NSTVKGYEPTPSGLRDALK 91
>UniRef50_Q9SN86 Cluster: Malate dehydrogenase, chloroplast
precursor; n=41; cellular organisms|Rep: Malate
dehydrogenase, chloroplast precursor - Arabidopsis
thaliana (Mouse-ear cress)
Length = 403
Score = 93.1 bits (221), Expect = 4e-18
Identities = 42/64 (65%), Positives = 52/64 (81%)
Frame = +1
Query: 352 QDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNSTVPI 531
+D +VVVIPAGVPRKPGMTRDDLFN NA IV+ + ++A N P A + +I+NPVNSTVPI
Sbjct: 149 KDVNVVVIPAGVPRKPGMTRDDLFNINANIVKTLVEAVAENCPNAFIHIISNPVNSTVPI 208
Query: 532 DSEV 543
+EV
Sbjct: 209 AAEV 212
Score = 69.3 bits (162), Expect = 5e-11
Identities = 35/57 (61%), Positives = 43/57 (75%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIK 355
IGQPL+LL+K +PLV+ L LYDIA V GVAADLSH NTP++V GP EL+ +K
Sbjct: 94 IGQPLSLLIKMSPLVSTLHLYDIANV-KGVAADLSHCNTPSQVRDFTGPSELADCLK 149
>UniRef50_A7SQS1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 254
Score = 92.7 bits (220), Expect = 5e-18
Identities = 43/64 (67%), Positives = 53/64 (82%)
Frame = +1
Query: 352 QDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNSTVPI 531
+ VV IPAGVPRKPGMTRDDLFNTNA IV++++ + A + PKAI+ +I+NPVNSTVPI
Sbjct: 35 EGCSVVAIPAGVPRKPGMTRDDLFNTNASIVKNLSEACAKHCPKAIICIISNPVNSTVPI 94
Query: 532 DSEV 543
SEV
Sbjct: 95 ASEV 98
Score = 44.4 bits (100), Expect = 0.002
Identities = 18/29 (62%), Positives = 26/29 (89%)
Frame = +2
Query: 269 GVAADLSHMNTPAKVSGHKGPEELSAAIK 355
GVAADLSH++T AKV+ H+GP++L AA++
Sbjct: 7 GVAADLSHISTRAKVTSHQGPDDLKAALE 35
>UniRef50_Q42972 Cluster: Malate dehydrogenase, glyoxysomal
precursor; n=11; Eukaryota|Rep: Malate dehydrogenase,
glyoxysomal precursor - Oryza sativa subsp. japonica
(Rice)
Length = 356
Score = 91.1 bits (216), Expect = 2e-17
Identities = 43/61 (70%), Positives = 50/61 (81%)
Frame = +1
Query: 361 DVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNSTVPIDSE 540
D+V+IPAGVPRKPGMTRDDLFN NA IVR + IA P AIV++I+NPVNSTVPI +E
Sbjct: 114 DLVIIPAGVPRKPGMTRDDLFNINAGIVRTLCEGIAKCCPNAIVNVISNPVNSTVPIAAE 173
Query: 541 V 543
V
Sbjct: 174 V 174
Score = 67.3 bits (157), Expect = 2e-10
Identities = 36/67 (53%), Positives = 42/67 (62%)
Frame = +2
Query: 152 FKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGP 331
FK IGQPLALL+K NPLV+ L LYD+ TPGV AD+SHMNT A V G G
Sbjct: 45 FKVAILGASGGIGQPLALLMKMNPLVSVLHLYDVVN-TPGVTADISHMNTGAVVRGFLGQ 103
Query: 332 EELSAAI 352
+L A+
Sbjct: 104 PQLENAL 110
>UniRef50_P08249 Cluster: Malate dehydrogenase, mitochondrial
precursor; n=514; cellular organisms|Rep: Malate
dehydrogenase, mitochondrial precursor - Mus musculus
(Mouse)
Length = 338
Score = 90.6 bits (215), Expect = 2e-17
Identities = 42/61 (68%), Positives = 50/61 (81%)
Frame = +1
Query: 361 DVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNSTVPIDSE 540
DVVVIPAGVPRKPGMTRDDLFNTNA IV + + A + P+A+V +I NPVNST+PI +E
Sbjct: 94 DVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMVCIIANPVNSTIPITAE 153
Query: 541 V 543
V
Sbjct: 154 V 154
Score = 90.2 bits (214), Expect = 3e-17
Identities = 49/95 (51%), Positives = 63/95 (66%)
Frame = +2
Query: 71 MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYD 250
M S +PA A++ ++FST++Q N K IGQPL+LLLK +PLV+RL LYD
Sbjct: 1 MLSALARPAGAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYD 57
Query: 251 IAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIK 355
IA TPGVAADLSH+ T A V G+ GPE+L +K
Sbjct: 58 IAH-TPGVAADLSHIETRANVKGYLGPEQLPDCLK 91
>UniRef50_P40926 Cluster: Malate dehydrogenase, mitochondrial
precursor; n=119; cellular organisms|Rep: Malate
dehydrogenase, mitochondrial precursor - Homo sapiens
(Human)
Length = 338
Score = 90.2 bits (214), Expect = 3e-17
Identities = 41/61 (67%), Positives = 50/61 (81%)
Frame = +1
Query: 361 DVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNSTVPIDSE 540
DVVVIPAGVPRKPGMTRDDLFNTNA IV + + A + P+A++ +I NPVNST+PI +E
Sbjct: 94 DVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVIANPVNSTIPITAE 153
Query: 541 V 543
V
Sbjct: 154 V 154
Score = 89.0 bits (211), Expect = 6e-17
Identities = 48/95 (50%), Positives = 63/95 (66%)
Frame = +2
Query: 71 MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYD 250
M S +P + A++ ++FST++Q N K IGQPL+LLLK +PLV+RL LYD
Sbjct: 1 MLSALARPVSAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYD 57
Query: 251 IAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIK 355
IA TPGVAADLSH+ T A V G+ GPE+L +K
Sbjct: 58 IAH-TPGVAADLSHIETKAAVKGYLGPEQLPDCLK 91
>UniRef50_Q9Y7R8 Cluster: Malate dehydrogenase; n=13; Dikarya|Rep:
Malate dehydrogenase - Schizosaccharomyces pombe
(Fission yeast)
Length = 341
Score = 88.2 bits (209), Expect = 1e-16
Identities = 41/58 (70%), Positives = 47/58 (81%)
Frame = +1
Query: 358 ADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNSTVPI 531
ADVV+IPAGVPRKPGMTRDDLF TNA IVRD+A + P+A ++TNPVNSTVPI
Sbjct: 98 ADVVIIPAGVPRKPGMTRDDLFATNASIVRDLAFAAGETCPEAKYLVVTNPVNSTVPI 155
Score = 66.1 bits (154), Expect = 5e-10
Identities = 34/67 (50%), Positives = 44/67 (65%)
Frame = +2
Query: 122 KNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNT 301
++FSTTS R FK IGQPL++LLK N V+ LAL+DI PGVAAD+ H+NT
Sbjct: 19 RSFSTTSSRAFKVAVLGAGGGIGQPLSMLLKLNDKVSELALFDIRG-APGVAADIGHINT 77
Query: 302 PAKVSGH 322
+ V G+
Sbjct: 78 TSNVVGY 84
>UniRef50_Q6BM17 Cluster: Malate dehydrogenase; n=4; Eukaryota|Rep:
Malate dehydrogenase - Debaryomyces hansenii (Yeast)
(Torulaspora hansenii)
Length = 346
Score = 87.8 bits (208), Expect = 1e-16
Identities = 42/63 (66%), Positives = 50/63 (79%)
Frame = +1
Query: 355 DADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNSTVPID 534
++D+VVIPAGVPRKPGMTR DLFN NA I+RDI SI P A + +I+NPVNSTVPI
Sbjct: 74 NSDLVVIPAGVPRKPGMTRADLFNINASIIRDIVGSIGKACPNAAILIISNPVNSTVPIA 133
Query: 535 SEV 543
+EV
Sbjct: 134 AEV 136
Score = 58.4 bits (135), Expect = 1e-07
Identities = 28/47 (59%), Positives = 38/47 (80%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHK 325
IGQPL+LLLK NP V+ L+L+D+ GVAADLSH+ +PAKV+G++
Sbjct: 13 IGQPLSLLLKLNPQVSELSLFDVVNAN-GVAADLSHICSPAKVTGYQ 58
>UniRef50_Q4QDF0 Cluster: Glycosomal malate dehydrogenase; n=9;
Trypanosomatidae|Rep: Glycosomal malate dehydrogenase -
Leishmania major
Length = 322
Score = 80.6 bits (190), Expect = 2e-14
Identities = 37/60 (61%), Positives = 47/60 (78%)
Frame = +1
Query: 361 DVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNSTVPIDSE 540
DV V+ AGVPRKPGMTRDDLF NA I+ D+ L+ A ++PKA+ ++TNPVNSTV I +E
Sbjct: 79 DVFVMVAGVPRKPGMTRDDLFKINAGIILDLVLTCASSSPKAVFCIVTNPVNSTVAIAAE 138
Score = 35.1 bits (77), Expect = 1.1
Identities = 20/39 (51%), Positives = 28/39 (71%), Gaps = 1/39 (2%)
Frame = +2
Query: 185 IGQPLALLL-KQNPLVTRLALYDIAPVTPGVAADLSHMN 298
IGQ L+LLL +Q P + L+L+D+ GVAADLSH++
Sbjct: 13 IGQSLSLLLVRQLPYGSTLSLFDVVGAA-GVAADLSHVD 50
>UniRef50_Q4Q3J3 Cluster: Malate dehydrogenase, putative; n=3;
Leishmania|Rep: Malate dehydrogenase, putative -
Leishmania major
Length = 331
Score = 78.2 bits (184), Expect = 1e-13
Identities = 32/61 (52%), Positives = 50/61 (81%)
Frame = +1
Query: 358 ADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNSTVPIDS 537
AD+V++ AG+PR+PGMT DDLFNTNA V +++ ++A APK+++ +I+NP+NS VP+ +
Sbjct: 76 ADLVLMSAGMPRRPGMTHDDLFNTNALTVNELSAAVARYAPKSVLAIISNPLNSMVPVAA 135
Query: 538 E 540
E
Sbjct: 136 E 136
Score = 50.4 bits (115), Expect = 3e-05
Identities = 31/58 (53%), Positives = 34/58 (58%), Gaps = 1/58 (1%)
Frame = +2
Query: 152 FKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHMNTPAKVSGH 322
FK IGQPLAL L QN V+ LALYDI V P GVA DLSH KV+G+
Sbjct: 9 FKVTVLGASGAIGQPLALALVQNKRVSELALYDI--VQPRGVAVDLSHFPRKVKVTGY 64
>UniRef50_P32419 Cluster: Malate dehydrogenase, peroxisomal; n=24;
Eukaryota|Rep: Malate dehydrogenase, peroxisomal -
Saccharomyces cerevisiae (Baker's yeast)
Length = 343
Score = 77.0 bits (181), Expect = 3e-13
Identities = 36/62 (58%), Positives = 46/62 (74%)
Frame = +1
Query: 355 DADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNSTVPID 534
+A VV+IPAGVPRKPG+TRDDLF NA IV+ + ++ AP A + +I+NPVNS VPI
Sbjct: 68 NAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIA 127
Query: 535 SE 540
E
Sbjct: 128 VE 129
Score = 50.4 bits (115), Expect = 3e-05
Identities = 24/46 (52%), Positives = 32/46 (69%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGH 322
+GQPL+LLLK +P V+ LALYDI G+ DLSH+NT + G+
Sbjct: 13 VGQPLSLLLKLSPYVSELALYDIR-AAEGIGKDLSHINTNSSCVGY 57
>UniRef50_Q6FL22 Cluster: Malate dehydrogenase; n=1; Candida
glabrata|Rep: Malate dehydrogenase - Candida glabrata
(Yeast) (Torulopsis glabrata)
Length = 373
Score = 75.4 bits (177), Expect = 8e-13
Identities = 34/61 (55%), Positives = 47/61 (77%)
Frame = +1
Query: 358 ADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNSTVPIDS 537
A VVVIPAGVPR+PG+TRDDLF NA IV+++ ++A + P A + +I+NPVNS +P+
Sbjct: 69 AAVVVIPAGVPRRPGITRDDLFKLNAGIVKNLVSNVAKHCPNARLLIISNPVNSLIPVAV 128
Query: 538 E 540
E
Sbjct: 129 E 129
Score = 55.2 bits (127), Expect = 9e-07
Identities = 28/57 (49%), Positives = 40/57 (70%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIK 355
+GQPL+LLLK N +++ LALYDI + GVA DLSH+NT A G+ +++ A+K
Sbjct: 13 VGQPLSLLLKLNTMISELALYDI-KLAEGVATDLSHINTNADCVGY-STDDIGQALK 67
>UniRef50_P22133 Cluster: Malate dehydrogenase, cytoplasmic; n=3;
Saccharomycetaceae|Rep: Malate dehydrogenase,
cytoplasmic - Saccharomyces cerevisiae (Baker's yeast)
Length = 377
Score = 74.5 bits (175), Expect = 1e-12
Identities = 37/61 (60%), Positives = 45/61 (73%), Gaps = 2/61 (3%)
Frame = +1
Query: 355 DADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIA--XNAPKAIVDMITNPVNSTVP 528
+A +VVIPAGVPRKPGMTRDDLFN NA I+ + SIA + K V +I+NPVNS VP
Sbjct: 94 NASIVVIPAGVPRKPGMTRDDLFNVNAGIISQLGDSIAECCDLSKVFVLVISNPVNSLVP 153
Query: 529 I 531
+
Sbjct: 154 V 154
Score = 37.9 bits (84), Expect = 0.15
Identities = 28/58 (48%), Positives = 32/58 (55%), Gaps = 12/58 (20%)
Frame = +2
Query: 185 IGQPLALLLK---------QNPLVTR--LALYDI-APVTPGVAADLSHMNTPAKVSGH 322
IGQ L+LLLK N VT LALYD+ GV ADLSH++TP VS H
Sbjct: 25 IGQSLSLLLKAQLQYQLKESNRSVTHIHLALYDVNQEAINGVTADLSHIDTPISVSSH 82
>UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep:
ADL164Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 381
Score = 73.3 bits (172), Expect = 3e-12
Identities = 37/60 (61%), Positives = 44/60 (73%), Gaps = 2/60 (3%)
Frame = +1
Query: 358 ADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSI--AXNAPKAIVDMITNPVNSTVPI 531
A VVVIPAGVPRKPGMTRDDL N NA I++ +A I A + K V +I+NPVNS VP+
Sbjct: 107 ASVVVIPAGVPRKPGMTRDDLININAGIIKTLAKGIAGACDLEKVFVLVISNPVNSLVPV 166
Score = 46.0 bits (104), Expect = 6e-04
Identities = 29/55 (52%), Positives = 33/55 (60%), Gaps = 9/55 (16%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVT--------RLALYDIAP-VTPGVAADLSHMNTPAKVSGH 322
IGQPL+LLLK LALYD+A GVAADLSH+NTP +VS H
Sbjct: 35 IGQPLSLLLKTQLAQVLGDANASLELALYDVAADALAGVAADLSHVNTPVEVSHH 89
>UniRef50_A7TSF5 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 387
Score = 72.9 bits (171), Expect = 4e-12
Identities = 33/59 (55%), Positives = 44/59 (74%)
Frame = +1
Query: 355 DADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNSTVPI 531
D+++V+IPAGVPRKPGMTRDDLFN NA I++ IA + V +I+NPVNS +P+
Sbjct: 112 DSNLVIIPAGVPRKPGMTRDDLFNINAGIIKGIAQELNTIDSTPFVLLISNPVNSLLPV 170
Score = 37.1 bits (82), Expect = 0.26
Identities = 25/52 (48%), Positives = 31/52 (59%), Gaps = 6/52 (11%)
Frame = +2
Query: 185 IGQPLALLLK-----QNPLVTRLALYDI-APVTPGVAADLSHMNTPAKVSGH 322
IGQ L+LLL+ N LAL+D+ V GV ADLSH+NT K+S H
Sbjct: 52 IGQSLSLLLRTSLQNNNDNQLHLALFDVNMKVLNGVHADLSHVNTNMKLSLH 103
>UniRef50_Q5ENS5 Cluster: Malate dehydrogenase; n=1; Heterocapsa
triquetra|Rep: Malate dehydrogenase - Heterocapsa
triquetra (Dinoflagellate)
Length = 402
Score = 70.9 bits (166), Expect = 2e-11
Identities = 33/60 (55%), Positives = 42/60 (70%)
Frame = +1
Query: 364 VVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNSTVPIDSEV 543
+V+IPAG+PRKPG TRDDLF NA I + I + A P A++ MI NPVNS VP +E+
Sbjct: 161 LVLIPAGMPRKPGQTRDDLFKINADIAKGIVEACAKYCPDAMLGMIVNPVNSVVPAMAEL 220
Score = 40.7 bits (91), Expect = 0.021
Identities = 23/60 (38%), Positives = 31/60 (51%), Gaps = 3/60 (5%)
Frame = +2
Query: 152 FKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDI-APVTP--GVAADLSHMNTPAKVSGH 322
FK IGQPL LL+ +P V L ++D+ + P GVA DL H+ A V G+
Sbjct: 81 FKVCVCGGAGGIGQPLCLLMAMDPNVKELCVFDLNVAMVPAQGVATDLGHLEKKAAVKGY 140
>UniRef50_UPI00005A0834 Cluster: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor; n=1; Canis lupus
familiaris|Rep: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor - Canis
familiaris
Length = 245
Score = 70.5 bits (165), Expect = 2e-11
Identities = 31/52 (59%), Positives = 41/52 (78%)
Frame = +1
Query: 388 PRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNSTVPIDSEV 543
PRKPGMTRDDLFNTNA +V + A + P+A++ +I+NPVNST+PI +EV
Sbjct: 61 PRKPGMTRDDLFNTNASVVATPTAACAQHCPEAMICVISNPVNSTIPIATEV 112
>UniRef50_Q9VU29 Cluster: Malate dehydrogenase; n=5;
Protostomia|Rep: Malate dehydrogenase - Drosophila
melanogaster (Fruit fly)
Length = 347
Score = 70.1 bits (164), Expect = 3e-11
Identities = 32/70 (45%), Positives = 46/70 (65%)
Frame = +1
Query: 322 QGT*GAISSHQDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMI 501
+G G + AD+VVIPAG+PRKPGM R+DL + NA + ++A + + P A++ I
Sbjct: 84 EGKNGLKKAMDKADIVVIPAGLPRKPGMKREDLVDVNASVACEVAFAASEVCPGAMLAFI 143
Query: 502 TNPVNSTVPI 531
TNP+N VPI
Sbjct: 144 TNPINVIVPI 153
Score = 58.0 bits (134), Expect = 1e-07
Identities = 32/69 (46%), Positives = 39/69 (56%)
Frame = +2
Query: 146 RNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHK 325
R K IGQPL+LLLK NP ++ L+LYDI T GV DLSH+NT A V +
Sbjct: 26 RGLKVAVVGSVGGIGQPLSLLLKHNPQISTLSLYDIKNTT-GVGVDLSHINTRASVCPFE 84
Query: 326 GPEELSAAI 352
G L A+
Sbjct: 85 GKNGLKKAM 93
>UniRef50_A3BMG8 Cluster: Putative uncharacterized protein; n=3;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 405
Score = 69.7 bits (163), Expect = 4e-11
Identities = 35/56 (62%), Positives = 42/56 (75%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAI 352
IGQPL+LL+K +PLV+ L LYDIA V GV ADL H NTPAKV+G G EEL+ +
Sbjct: 89 IGQPLSLLVKMSPLVSALHLYDIANVD-GVTADLGHCNTPAKVAGFTGKEELAGCL 143
Score = 64.9 bits (151), Expect = 1e-09
Identities = 29/40 (72%), Positives = 34/40 (85%)
Frame = +1
Query: 361 DVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAP 480
DVVVIPAGVPRKPGMTRDDLF NA IVR++ ++A +AP
Sbjct: 147 DVVVIPAGVPRKPGMTRDDLFGINAGIVRELVEAVADHAP 186
>UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3;
Actinomycetales|Rep: Lactate/malate dehydrogenase -
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 330
Score = 68.5 bits (160), Expect = 9e-11
Identities = 31/54 (57%), Positives = 42/54 (77%)
Frame = +1
Query: 355 DADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVN 516
DA +V+I AGVPRKPGM+R DL TNA IVR +A +IA AP A+V +++NP++
Sbjct: 87 DASIVIITAGVPRKPGMSRMDLLETNARIVRGVAENIAKYAPSAVVIVVSNPLD 140
>UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces
cerevisiae YOL126c MDH2 malate dehydrogenase; n=1;
Kluyveromyces lactis|Rep: Similar to sp|P22133
Saccharomyces cerevisiae YOL126c MDH2 malate
dehydrogenase - Kluyveromyces lactis (Yeast) (Candida
sphaerica)
Length = 404
Score = 65.7 bits (153), Expect = 7e-10
Identities = 32/61 (52%), Positives = 43/61 (70%), Gaps = 2/61 (3%)
Frame = +1
Query: 355 DADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIA--XNAPKAIVDMITNPVNSTVP 528
+A VV+IPAGVPRKPGM+RDDL NA I++ + IA + K V +I+NP+NS VP
Sbjct: 128 NASVVIIPAGVPRKPGMSRDDLIGVNAKIIKSLGEDIAKYCDLNKVHVLVISNPINSLVP 187
Query: 529 I 531
+
Sbjct: 188 L 188
Score = 38.3 bits (85), Expect = 0.11
Identities = 28/66 (42%), Positives = 37/66 (56%), Gaps = 10/66 (15%)
Frame = +2
Query: 185 IGQPLALLLKQN-----PLVT----RLALYDI-APVTPGVAADLSHMNTPAKVSGHKGPE 334
IGQ L+LLLK N P T RL+LYD+ G AADLSH++TP + H P+
Sbjct: 58 IGQSLSLLLKSNAGFLLPHETSTHIRLSLYDVNKDAIVGTAADLSHIDTPITTTAHY-PD 116
Query: 335 ELSAAI 352
+ + I
Sbjct: 117 DSNGGI 122
>UniRef50_A7TL95 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 365
Score = 64.9 bits (151), Expect = 1e-09
Identities = 28/61 (45%), Positives = 45/61 (73%), Gaps = 1/61 (1%)
Frame = +1
Query: 352 QDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAP-KAIVDMITNPVNSTVP 528
+ +++V++ AG+PRKPGMTRDDLF NA I++++ + A AP + +I+NPVNS +P
Sbjct: 69 EGSELVIVTAGIPRKPGMTRDDLFKINAKIIQNLTVKYAKFAPVHCKLLIISNPVNSLIP 128
Query: 529 I 531
+
Sbjct: 129 V 129
Score = 63.7 bits (148), Expect = 3e-09
Identities = 30/51 (58%), Positives = 38/51 (74%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEE 337
IGQPL+LLLK NP V+ LALYDI+ +T GVA DLSH+NT + G+ E+
Sbjct: 13 IGQPLSLLLKLNPYVSDLALYDISDITAGVAKDLSHINTNSDSEGYNKDED 63
>UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular
organisms|Rep: Malate dehydrogenase - Silicibacter
pomeroyi
Length = 320
Score = 64.1 bits (149), Expect = 2e-09
Identities = 34/89 (38%), Positives = 51/89 (57%), Gaps = 2/89 (2%)
Frame = +1
Query: 265 PRRRSRPFPHEHPSQG--QRPQGT*GAISSHQDADVVVIPAGVPRKPGMTRDDLFNTNAX 438
P ++ PS+G + +GT + + ADV ++ AGVPRKPGM+RDDL N
Sbjct: 40 PEGKALDIAESGPSEGFDAKLKGT-QSYADIAGADVCIVTAGVPRKPGMSRDDLLGINLK 98
Query: 439 IVRDIALSIAXNAPKAIVDMITNPVNSTV 525
+++ + I NAP A V ITNP+++ V
Sbjct: 99 VMKSVGEGIRDNAPDAFVICITNPLDAMV 127
>UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Rep:
Malate dehydrogenase - Brucella melitensis
Length = 320
Score = 63.7 bits (148), Expect = 3e-09
Identities = 28/58 (48%), Positives = 39/58 (67%)
Frame = +1
Query: 352 QDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNSTV 525
+ ADVV++ AGVPRKPGM+RDDL N ++ + I AP+A V ITNP+++ V
Sbjct: 70 EGADVVIVTAGVPRKPGMSRDDLLGINLKVMEQVGAGIKKYAPEAFVICITNPLDAMV 127
>UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2;
Toxoplasma gondii|Rep: Mitochondrial
malate-dehydrogenase - Toxoplasma gondii
Length = 470
Score = 63.3 bits (147), Expect = 4e-09
Identities = 30/60 (50%), Positives = 40/60 (66%)
Frame = +1
Query: 352 QDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNSTVPI 531
+DADV+++ AGVPRKPGM+RDDL NA I+ + +I P A V ITNP++ V I
Sbjct: 224 KDADVIIVTAGVPRKPGMSRDDLLAINAKIMGQVGEAIKQYCPNAFVICITNPLDVMVYI 283
>UniRef50_Q9VU28 Cluster: Malate dehydrogenase; n=3; Sophophora|Rep:
Malate dehydrogenase - Drosophila melanogaster (Fruit
fly)
Length = 349
Score = 62.9 bits (146), Expect = 5e-09
Identities = 31/67 (46%), Positives = 42/67 (62%)
Frame = +1
Query: 343 SSHQDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNST 522
S+ ADVVV+ AG+PR PGM RD L N + +A +I+ +P+A + ITNPVN
Sbjct: 86 SAVSGADVVVVAAGMPRLPGMQRDHLMAANGNVAVKVATAISNASPRAHLAFITNPVNMI 145
Query: 523 VPIDSEV 543
VP +EV
Sbjct: 146 VPAAAEV 152
Score = 54.4 bits (125), Expect = 2e-06
Identities = 28/69 (40%), Positives = 42/69 (60%)
Frame = +2
Query: 146 RNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHK 325
R K IGQPL+LLL++ P + LAL+D++ + G+A DLSH++ KV G
Sbjct: 21 RTLKVAVVGAGGGIGQPLSLLLRRCPGIDELALHDLSEMK-GIATDLSHISQTGKVIGFT 79
Query: 326 GPEELSAAI 352
G +EL +A+
Sbjct: 80 GEKELESAV 88
>UniRef50_Q64P62 Cluster: Malate dehydrogenase; n=28;
Bacteroidetes|Rep: Malate dehydrogenase - Bacteroides
fragilis
Length = 313
Score = 62.9 bits (146), Expect = 5e-09
Identities = 26/55 (47%), Positives = 43/55 (78%)
Frame = +1
Query: 355 DADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNS 519
++DVVVI +G+PRKPGMTR++L NA IV+ +A ++ +P AI+ +I+NP+++
Sbjct: 71 NSDVVVITSGIPRKPGMTREELIGVNAGIVKSVAENLLKYSPNAIIVVISNPMDT 125
>UniRef50_Q017A6 Cluster: Malate dehydrogenase; n=2; cellular
organisms|Rep: Malate dehydrogenase - Ostreococcus tauri
Length = 477
Score = 61.3 bits (142), Expect = 1e-08
Identities = 28/47 (59%), Positives = 36/47 (76%)
Frame = +1
Query: 403 MTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNSTVPIDSEV 543
MTRDDLF N IV+ + +IA N P A+++MI+NPVNSTVPI +EV
Sbjct: 1 MTRDDLFAINGGIVKGLVEAIADNCPNAMINMISNPVNSTVPIAAEV 47
>UniRef50_Q8TWG5 Cluster: Malate dehydrogenase; n=2;
Euryarchaeota|Rep: Malate dehydrogenase - Methanopyrus
kandleri
Length = 317
Score = 61.3 bits (142), Expect = 1e-08
Identities = 28/54 (51%), Positives = 38/54 (70%)
Frame = +1
Query: 355 DADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVN 516
DADV+V+ AG+PRKPG TR DL NA I++ +A P+AIV ++TNPV+
Sbjct: 73 DADVIVMTAGIPRKPGQTRLDLTKDNAAIIKKYLEGVAEENPEAIVLVVTNPVD 126
>UniRef50_Q3J7E7 Cluster: Malate dehydrogenase; n=5;
Gammaproteobacteria|Rep: Malate dehydrogenase -
Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
Length = 311
Score = 60.9 bits (141), Expect = 2e-08
Identities = 26/54 (48%), Positives = 41/54 (75%)
Frame = +1
Query: 355 DADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVN 516
D+D+VVI AG PRKPGM+R D+ ++N I+ DI ++ AP+++V ++TNPV+
Sbjct: 72 DSDLVVITAGKPRKPGMSRSDVLDSNLPIITDIMNNVMRFAPQSLVMIVTNPVD 125
>UniRef50_O08349 Cluster: Malate dehydrogenase; n=1; Archaeoglobus
fulgidus|Rep: Malate dehydrogenase - Archaeoglobus
fulgidus
Length = 294
Score = 60.1 bits (139), Expect = 3e-08
Identities = 25/53 (47%), Positives = 41/53 (77%)
Frame = +1
Query: 358 ADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVN 516
++++V+ AG+ RKPGMTR DL + NA I++DIA I NAP++ + ++TNP++
Sbjct: 70 SEIIVVTAGLARKPGMTRLDLAHKNAGIIKDIAKKIVENAPESKILVVTNPMD 122
>UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD binding
domain protein; n=2; Campylobacter|Rep: Lactate/malate
dehydrogenase, NAD binding domain protein -
Campylobacter curvus 525.92
Length = 297
Score = 59.3 bits (137), Expect = 6e-08
Identities = 28/56 (50%), Positives = 39/56 (69%)
Frame = +1
Query: 358 ADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNSTV 525
+D+VV+ AG PRK G TR+DL NA +V+ A +IA AP AIV ++TNP++ V
Sbjct: 70 SDIVVVTAGSPRKEGQTREDLLLKNAQVVKQTAQNIAKFAPNAIVIIVTNPLDVMV 125
>UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|Rep:
Malate dehydrogenase - Plasmodium falciparum
Length = 313
Score = 59.3 bits (137), Expect = 6e-08
Identities = 27/64 (42%), Positives = 41/64 (64%)
Frame = +1
Query: 340 ISSHQDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNS 519
I +DAD++VI AGV RK GMTR+DL N I++ +A S+ + KA V ++NP++
Sbjct: 64 IEDIKDADIIVITAGVQRKEGMTREDLIGVNGKIMKSVAESVKLHCSKAFVICVSNPLDI 123
Query: 520 TVPI 531
V +
Sbjct: 124 MVNV 127
>UniRef50_Q8ZVB2 Cluster: Malate dehydrogenase; n=14;
Thermoprotei|Rep: Malate dehydrogenase - Pyrobaculum
aerophilum
Length = 309
Score = 59.3 bits (137), Expect = 6e-08
Identities = 25/56 (44%), Positives = 39/56 (69%)
Frame = +1
Query: 352 QDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNS 519
+ +D++++ AG+PRKPGMTR+ L NA IV +I I AP +IV + TNP+++
Sbjct: 67 EGSDLIIVTAGLPRKPGMTREQLLEANAKIVAEIGREIKKYAPDSIVILTTNPLDA 122
>UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|Rep:
Malate dehydrogenase 1 - Aquifex aeolicus
Length = 335
Score = 59.3 bits (137), Expect = 6e-08
Identities = 28/55 (50%), Positives = 38/55 (69%)
Frame = +1
Query: 352 QDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVN 516
+ +D+VVI AG PR+PGM+R+DL N I+ IA I AP AIV ++TNPV+
Sbjct: 84 EGSDIVVITAGFPRRPGMSREDLLEANIRIISVIADRIKRYAPDAIVIVVTNPVD 138
>UniRef50_P16115 Cluster: L-lactate dehydrogenase; n=4;
Thermotogaceae|Rep: L-lactate dehydrogenase - Thermotoga
maritima
Length = 319
Score = 58.8 bits (136), Expect = 8e-08
Identities = 26/61 (42%), Positives = 43/61 (70%)
Frame = +1
Query: 334 GAISSHQDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPV 513
G + + +DVV++ AGVP+KPG TR L NA ++++IA +++ AP +IV ++TNPV
Sbjct: 60 GDYADLKGSDVVIVAAGVPQKPGETRLQLLGRNARVMKEIARNVSKYAPDSIVIVVTNPV 119
Query: 514 N 516
+
Sbjct: 120 D 120
>UniRef50_Q86DP2 Cluster: Malate dehydrogenase; n=11; Fungi/Metazoa
group|Rep: Malate dehydrogenase - Plicopurpura patula
Length = 229
Score = 58.4 bits (135), Expect = 1e-07
Identities = 29/43 (67%), Positives = 33/43 (76%)
Frame = +1
Query: 415 DLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNSTVPIDSEV 543
DLFNTNA IVRD+ IA P A++ +ITNPVNSTVPI SEV
Sbjct: 1 DLFNTNAGIVRDLTDRIAKVCPTAMLGIITNPVNSTVPIASEV 43
>UniRef50_Q979N9 Cluster: Malate dehydrogenase; n=4;
Thermoplasmatales|Rep: Malate dehydrogenase -
Thermoplasma volcanium
Length = 325
Score = 58.0 bits (134), Expect = 1e-07
Identities = 22/55 (40%), Positives = 41/55 (74%)
Frame = +1
Query: 352 QDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVN 516
+ +DV+V+ AG+ RKPGM+R+DLF+ N I+ D++ +I +P +I+ +++NP +
Sbjct: 75 EGSDVIVVTAGMARKPGMSREDLFDKNVEIIADVSKNIKKYSPDSIIVVVSNPAD 129
>UniRef50_A6Q7S2 Cluster: Malate dehydrogenase, NAD-dependent; n=1;
Sulfurovum sp. NBC37-1|Rep: Malate dehydrogenase,
NAD-dependent - Sulfurovum sp. (strain NBC37-1)
Length = 320
Score = 57.2 bits (132), Expect = 2e-07
Identities = 27/55 (49%), Positives = 38/55 (69%)
Frame = +1
Query: 352 QDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVN 516
+ +DVV+I AG PR PGM+RDDL NA IV+ + I AP AIV +++NP++
Sbjct: 72 EGSDVVIITAGAPRTPGMSRDDLLFKNADIVKCYSREIKEYAPDAIVIVVSNPLD 126
>UniRef50_A7I2F1 Cluster: Malate dehydrogenase; n=1; Campylobacter
hominis ATCC BAA-381|Rep: Malate dehydrogenase -
Campylobacter hominis (strain ATCC BAA-381 / LMG 19568 /
NCTC 13146 /CH001A)
Length = 297
Score = 56.8 bits (131), Expect = 3e-07
Identities = 26/56 (46%), Positives = 40/56 (71%)
Frame = +1
Query: 352 QDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNS 519
+++D+VVI AG R+ G +R DL N NA I+ A ++A AP+AI+ +ITNPV++
Sbjct: 69 KNSDIVVITAGKTRQAGQSRADLLNDNAKIISSCAKNVAKYAPEAIIILITNPVDT 124
>UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;
Ignicoccus hospitalis KIN4/I|Rep: malate dehydrogenase
(NAD) - Ignicoccus hospitalis KIN4/I
Length = 311
Score = 56.4 bits (130), Expect = 4e-07
Identities = 30/68 (44%), Positives = 40/68 (58%)
Frame = +1
Query: 340 ISSHQDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNS 519
+S ++AD +VI AG PRK M+R DL NA I+RDI + P A +ITNPV+
Sbjct: 69 VSKVENADAIVITAGKPRKADMSRRDLAKVNAQIIRDIGDKLRDRNPGAFYMVITNPVDV 128
Query: 520 TVPIDSEV 543
I S+V
Sbjct: 129 MTMILSDV 136
>UniRef50_A3EWH3 Cluster: Malate/lactate dehydrogenase; n=1;
Leptospirillum sp. Group II UBA|Rep: Malate/lactate
dehydrogenase - Leptospirillum sp. Group II UBA
Length = 320
Score = 56.4 bits (130), Expect = 4e-07
Identities = 25/61 (40%), Positives = 41/61 (67%)
Frame = +1
Query: 334 GAISSHQDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPV 513
G + + + VVV+ AG RKPGM+R+DL + N I+ ++A I +AP ++V M+TNP+
Sbjct: 67 GNYETIEGSSVVVVTAGFSRKPGMSREDLLHKNGDIMIEVAEKIRKHAPDSVVIMVTNPM 126
Query: 514 N 516
+
Sbjct: 127 D 127
>UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter
hepaticus|Rep: Malate dehydrogenase - Helicobacter
hepaticus
Length = 315
Score = 55.6 bits (128), Expect = 7e-07
Identities = 22/55 (40%), Positives = 43/55 (78%)
Frame = +1
Query: 355 DADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNS 519
+++VV+I AG PR P MTR+DL NA I+++I+ ++A AP++++ +++NP+++
Sbjct: 72 ESEVVIITAGFPRTPNMTRNDLLLKNASIIQEISSNVARIAPQSLLIVVSNPLDA 126
>UniRef50_Q18WQ6 Cluster: Malate dehydrogenase, NAD-dependent; n=2;
Desulfitobacterium hafniense|Rep: Malate dehydrogenase,
NAD-dependent - Desulfitobacterium hafniense (strain
DCB-2)
Length = 320
Score = 54.8 bits (126), Expect = 1e-06
Identities = 23/54 (42%), Positives = 39/54 (72%)
Frame = +1
Query: 355 DADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVN 516
D+DVVVI AG+ RKPGM+R++L + NA IV + + ++P + + +++NPV+
Sbjct: 71 DSDVVVITAGIARKPGMSRNELCDINAGIVTHVVRQVVQHSPNSTLIILSNPVD 124
>UniRef50_P11386 Cluster: Malate dehydrogenase; n=6;
Sulfolobaceae|Rep: Malate dehydrogenase - Sulfolobus
acidocaldarius
Length = 306
Score = 54.8 bits (126), Expect = 1e-06
Identities = 27/53 (50%), Positives = 35/53 (66%)
Frame = +1
Query: 358 ADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVN 516
AD+VVI AG PRKPGM+R DLF NA I+ D+A + A+ M+ NPV+
Sbjct: 71 ADIVVITAGKPRKPGMSRRDLFIDNAKIMIDLAKKLPKKNKGAMYIMVANPVD 123
>UniRef50_A4BB89 Cluster: Lactate dehydrogenase; n=2;
Gammaproteobacteria|Rep: Lactate dehydrogenase -
Reinekea sp. MED297
Length = 319
Score = 54.4 bits (125), Expect = 2e-06
Identities = 28/52 (53%), Positives = 33/52 (63%)
Frame = +1
Query: 355 DADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNP 510
DAD+VVI AG K G TRDDL N+ I DIA I AP AI+ ++TNP
Sbjct: 70 DADIVVITAGAQIKEGQTRDDLAEINSRITVDIAQKIETVAPNAILLVVTNP 121
>UniRef50_Q7NHJ3 Cluster: Malate dehydrogenase; n=13; cellular
organisms|Rep: Malate dehydrogenase - Gloeobacter
violaceus
Length = 325
Score = 54.0 bits (124), Expect = 2e-06
Identities = 23/54 (42%), Positives = 38/54 (70%)
Frame = +1
Query: 358 ADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNS 519
+DV+V+ AG R+PGM+RDDL TN IV ++ ++P+A V ++TNP+++
Sbjct: 77 SDVLVVAAGFARQPGMSRDDLLLTNTRIVFEVTQKAVAHSPEATVVVVTNPLDA 130
>UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 312
Score = 53.6 bits (123), Expect = 3e-06
Identities = 27/61 (44%), Positives = 37/61 (60%)
Frame = +1
Query: 334 GAISSHQDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPV 513
G S +DAD++VI AGVPR PG TR D+ + + VRDI ++ K I+ ITNP
Sbjct: 65 GDYSDCKDADIIVISAGVPRLPGQTRLDVLDGSVECVRDIVSNLNKIEIKGIIITITNPA 124
Query: 514 N 516
+
Sbjct: 125 D 125
>UniRef50_A4L2P0 Cluster: L-lactate dehydrogenase; n=4;
Lactobacillus|Rep: L-lactate dehydrogenase -
Lactobacillus reuteri
Length = 312
Score = 53.6 bits (123), Expect = 3e-06
Identities = 28/70 (40%), Positives = 37/70 (52%)
Frame = +1
Query: 334 GAISSHQDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPV 513
G DADVVVI AG+PRKPG TR DL N N I++ I I + + + +NPV
Sbjct: 67 GTYEDAADADVVVITAGIPRKPGETRLDLVNKNTTILKSIIKPIVKSGFTGVFVISSNPV 126
Query: 514 NSTVPIDSEV 543
+ I +
Sbjct: 127 DILTTIAQRI 136
>UniRef50_A0RPE9 Cluster: Malate dehydrogenase; n=1; Campylobacter
fetus subsp. fetus 82-40|Rep: Malate dehydrogenase -
Campylobacter fetus subsp. fetus (strain 82-40)
Length = 306
Score = 53.2 bits (122), Expect = 4e-06
Identities = 26/58 (44%), Positives = 38/58 (65%)
Frame = +1
Query: 352 QDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNSTV 525
+D D+VVI AG RK G +RDDL NA IV + ++ APK+I+ ++TNP++ V
Sbjct: 68 KDFDIVVITAGFARKDGQSRDDLAMMNAKIVSHSSKMVSKFAPKSIIIVVTNPLDIMV 125
>UniRef50_Q7M9A7 Cluster: Malate dehydrogenase; n=4;
Epsilonproteobacteria|Rep: Malate dehydrogenase -
Wolinella succinogenes
Length = 314
Score = 52.8 bits (121), Expect = 5e-06
Identities = 23/61 (37%), Positives = 39/61 (63%)
Frame = +1
Query: 343 SSHQDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNST 522
S + DVVV AG PR+PGM+RDDL NA ++R + + ++++ M++NP+++
Sbjct: 63 SDLRGCDVVVFCAGSPRQPGMSRDDLLLANAKVIRTVLSEVKPYIQESVLVMVSNPLDAM 122
Query: 523 V 525
V
Sbjct: 123 V 123
>UniRef50_O26290 Cluster: Malate dehydrogenase; n=2;
Methanobacteriaceae|Rep: Malate dehydrogenase -
Methanobacterium thermoautotrophicum
Length = 325
Score = 52.4 bits (120), Expect = 7e-06
Identities = 27/51 (52%), Positives = 33/51 (64%)
Frame = +1
Query: 364 VVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVN 516
+VVI AGVPR M RDDL N IV D A IA AP +I+ ++TNPV+
Sbjct: 75 IVVITAGVPRTADMDRDDLAFKNGRIVADYARQIARFAPDSIILVVTNPVD 125
>UniRef50_A0RXX8 Cluster: Malate/L-lactate dehydrogenase; n=1;
Cenarchaeum symbiosum|Rep: Malate/L-lactate
dehydrogenase - Cenarchaeum symbiosum
Length = 302
Score = 52.0 bits (119), Expect = 9e-06
Identities = 23/58 (39%), Positives = 37/58 (63%)
Frame = +1
Query: 343 SSHQDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVN 516
S + +D+VV+ AG RKPGMTR DL NA IV+ + + +A +++ +TNP++
Sbjct: 64 SDMEGSDIVVVVAGAGRKPGMTRMDLLKINAGIVKGVVEKVKEHAKDSMIIPVTNPLD 121
>UniRef50_Q3ZZJ7 Cluster: Malate dehydrogenase; n=5; cellular
organisms|Rep: Malate dehydrogenase - Dehalococcoides
sp. (strain CBDB1)
Length = 307
Score = 51.2 bits (117), Expect = 2e-05
Identities = 21/54 (38%), Positives = 38/54 (70%)
Frame = +1
Query: 358 ADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNS 519
+++VVI AG+ RKPGMTR++L N I+ D+ + +P+A + +++NPV++
Sbjct: 70 SEIVVITAGIARKPGMTREELLAINQKIMTDVVSNCLKYSPEATLVVVSNPVDT 123
>UniRef50_Q892U0 Cluster: L-lactate dehydrogenase; n=12;
Bacteria|Rep: L-lactate dehydrogenase - Clostridium
tetani
Length = 316
Score = 51.2 bits (117), Expect = 2e-05
Identities = 24/61 (39%), Positives = 37/61 (60%)
Frame = +1
Query: 334 GAISSHQDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPV 513
G +D+D+V+I AG KPG TR DL N N I + I + +PK+I+ +++NPV
Sbjct: 65 GDYEDTKDSDIVIITAGAGPKPGETRLDLINKNYEIFKGIVPEVVKYSPKSILLVVSNPV 124
Query: 514 N 516
+
Sbjct: 125 D 125
>UniRef50_Q6A9C3 Cluster: L-lactate dehydrogenase; n=2;
Propionibacterium acnes|Rep: L-lactate dehydrogenase -
Propionibacterium acnes
Length = 319
Score = 50.8 bits (116), Expect = 2e-05
Identities = 24/62 (38%), Positives = 35/62 (56%)
Frame = +1
Query: 355 DADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNSTVPID 534
D+DVV I AG +KPG TR DL NA I+R + + +P A+ ++TNP + +
Sbjct: 77 DSDVVFITAGARQKPGQTRLDLAGVNANILRSLMPQLVEQSPNALFVLVTNPCDVLTVVA 136
Query: 535 SE 540
E
Sbjct: 137 QE 138
>UniRef50_Q8XP62 Cluster: L-lactate dehydrogenase; n=11;
Clostridium|Rep: L-lactate dehydrogenase - Clostridium
perfringens
Length = 317
Score = 50.8 bits (116), Expect = 2e-05
Identities = 23/61 (37%), Positives = 38/61 (62%)
Frame = +1
Query: 334 GAISSHQDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPV 513
G + +D+D+V+I AGV KPG TR D+ N N I + I + +P +I+ +++NPV
Sbjct: 66 GDYADTKDSDIVIITAGVGPKPGETRLDIINKNLKIFQSIVPEVVKYSPNSILLVVSNPV 125
Query: 514 N 516
+
Sbjct: 126 D 126
>UniRef50_P59390 Cluster: L-lactate dehydrogenase 2; n=8;
Lactobacillus|Rep: L-lactate dehydrogenase 2 -
Lactobacillus plantarum
Length = 309
Score = 50.8 bits (116), Expect = 2e-05
Identities = 25/61 (40%), Positives = 35/61 (57%)
Frame = +1
Query: 334 GAISSHQDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPV 513
G + +DAD+VVI AGVPRKPG +R DL N N I+ I + + + +NPV
Sbjct: 65 GEYADARDADIVVITAGVPRKPGESRLDLINRNTKILESIVKPVVASGFNGCFVISSNPV 124
Query: 514 N 516
+
Sbjct: 125 D 125
>UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;
Candidatus Methanoregula boonei 6A8|Rep: L-lactate
dehydrogenase precursor - Methanoregula boonei (strain
6A8)
Length = 332
Score = 50.0 bits (114), Expect = 4e-05
Identities = 25/53 (47%), Positives = 33/53 (62%)
Frame = +1
Query: 358 ADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVN 516
+D+VVI AG PR PG R DL NA I+ +A +I AP + M+TNPV+
Sbjct: 74 SDIVVITAGTPRGPGQNRLDLALGNARIIAPMARTIGTIAPDTKIIMVTNPVD 126
>UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3;
Methanomicrobiales|Rep: L-lactate dehydrogenase -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 319
Score = 50.0 bits (114), Expect = 4e-05
Identities = 24/53 (45%), Positives = 36/53 (67%)
Frame = +1
Query: 358 ADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVN 516
+D++V+ +GVPRK TR DL NA IV+ A + AP+AI+ ++TNPV+
Sbjct: 74 SDIIVLTSGVPRKATQTRLDLALENARIVKVFAEQVGRMAPEAILLVVTNPVD 126
>UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasma
hyopneumoniae|Rep: L-lactate dehydrogenase - Mycoplasma
hyopneumoniae
Length = 315
Score = 50.0 bits (114), Expect = 4e-05
Identities = 24/55 (43%), Positives = 35/55 (63%)
Frame = +1
Query: 352 QDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVN 516
+DAD +VI AG P+KPG TR +L N I+R+IAL + + I ++ NPV+
Sbjct: 70 KDADFIVITAGRPQKPGETRLELVADNIRIIREIALKVKESGFSGISIIVANPVD 124
>UniRef50_Q81K80 Cluster: L-lactate dehydrogenase 2; n=12;
Firmicutes|Rep: L-lactate dehydrogenase 2 - Bacillus
anthracis
Length = 314
Score = 50.0 bits (114), Expect = 4e-05
Identities = 26/61 (42%), Positives = 36/61 (59%)
Frame = +1
Query: 334 GAISSHQDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPV 513
G+ + +DAD+VVI AG+P+KPG TR DL N I + I I + I + TNPV
Sbjct: 66 GSYADCKDADLVVITAGLPQKPGETRLDLVEKNTKIFKQIVRGIMDSGFDGIFLIATNPV 125
Query: 514 N 516
+
Sbjct: 126 D 126
>UniRef50_P50933 Cluster: L-lactate dehydrogenase; n=7;
Bacteria|Rep: L-lactate dehydrogenase - Deinococcus
radiodurans
Length = 304
Score = 49.6 bits (113), Expect = 5e-05
Identities = 25/61 (40%), Positives = 36/61 (59%)
Frame = +1
Query: 334 GAISSHQDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPV 513
G S DA VV++ AG +KPG +R DL NA I R++ I AP A++ + +NPV
Sbjct: 60 GGHSELADAQVVILTAGANQKPGESRLDLLEKNADIFRELVPQITRAAPDAVLLVTSNPV 119
Query: 514 N 516
+
Sbjct: 120 D 120
>UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex
aeolicus|Rep: Malate dehydrogenase 2 - Aquifex aeolicus
Length = 334
Score = 48.8 bits (111), Expect = 8e-05
Identities = 21/54 (38%), Positives = 37/54 (68%)
Frame = +1
Query: 358 ADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNS 519
+D+VVI AG+PR+ GM+R+DL N I++ +I A +I+ +++NPV++
Sbjct: 89 SDIVVITAGIPRREGMSREDLLYENLKILKKFTDAIKEYAKDSIIIVVSNPVDT 142
>UniRef50_Q7UY63 Cluster: L-lactate/malate dehydrogenase; n=2;
Planctomycetaceae|Rep: L-lactate/malate dehydrogenase -
Rhodopirellula baltica
Length = 304
Score = 48.4 bits (110), Expect = 1e-04
Identities = 25/63 (39%), Positives = 39/63 (61%), Gaps = 1/63 (1%)
Frame = +1
Query: 334 GAISSHQDADVVVIPAGVP-RKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNP 510
G I+ +D+DV++ A VP R P TR ++ N I+RD +A +P AIV M++NP
Sbjct: 61 GEIADSKDSDVIIFTASVPFRYPNQTRLEMGIDNMPILRDWMPGLAKASPNAIVVMVSNP 120
Query: 511 VNS 519
V++
Sbjct: 121 VDA 123
>UniRef50_Q07841 Cluster: Malate dehydrogenase; n=7;
Halobacteriaceae|Rep: Malate dehydrogenase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 304
Score = 48.4 bits (110), Expect = 1e-04
Identities = 26/61 (42%), Positives = 34/61 (55%)
Frame = +1
Query: 334 GAISSHQDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPV 513
G +DVVVI AG+PR+PG TR DL NA I+ DI S+ + I +NPV
Sbjct: 64 GGYEDTAGSDVVVITAGIPRQPGQTRIDLAGDNAPIMEDIQSSLDEHNDDYISLTTSNPV 123
Query: 514 N 516
+
Sbjct: 124 D 124
>UniRef50_A2SNY0 Cluster: Malate/lactate dehydrogenases-like
protein; n=1; Methylibium petroleiphilum PM1|Rep:
Malate/lactate dehydrogenases-like protein - Methylibium
petroleiphilum (strain PM1)
Length = 432
Score = 48.0 bits (109), Expect = 1e-04
Identities = 21/52 (40%), Positives = 34/52 (65%)
Frame = +1
Query: 358 ADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPV 513
A+ +VI AG PR+PGM+R DL NA I+ + I +AP + + +++NP+
Sbjct: 193 AEYIVITAGKPRQPGMSRTDLTVVNAEIMTSVCRGIRTHAPNSTLVIVSNPL 244
>UniRef50_A1HSK3 Cluster: Lactate/malate dehydrogenase; n=1;
Thermosinus carboxydivorans Nor1|Rep: Lactate/malate
dehydrogenase - Thermosinus carboxydivorans Nor1
Length = 303
Score = 48.0 bits (109), Expect = 1e-04
Identities = 22/61 (36%), Positives = 35/61 (57%)
Frame = +1
Query: 334 GAISSHQDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPV 513
G ++ AD+VVI AG+PRK R L + NA ++ D+ +P I+ M+TNP+
Sbjct: 60 GEMADTAGADIVVITAGIPRKADEPRVLLLSRNAALIADLVRQAVHYSPNCIIFMVTNPL 119
Query: 514 N 516
+
Sbjct: 120 D 120
>UniRef50_A7DRG3 Cluster: Lactate/malate dehydrogenase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
Lactate/malate dehydrogenase - Candidatus Nitrosopumilus
maritimus SCM1
Length = 304
Score = 48.0 bits (109), Expect = 1e-04
Identities = 23/62 (37%), Positives = 38/62 (61%)
Frame = +1
Query: 358 ADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNSTVPIDS 537
+++VV+ AG RKPGMTR DL NA IV+ + ++ A +++ +TNP++ I
Sbjct: 69 SNIVVVVAGSGRKPGMTRMDLLKINASIVKSVVENVKKYADDSMIIPVTNPLDPMAYITY 128
Query: 538 EV 543
+V
Sbjct: 129 KV 130
>UniRef50_Q6KIP9 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
mobile|Rep: L-lactate dehydrogenase - Mycoplasma mobile
Length = 318
Score = 48.0 bits (109), Expect = 1e-04
Identities = 25/58 (43%), Positives = 37/58 (63%)
Frame = +1
Query: 343 SSHQDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVN 516
S +D DVVVI AG P+KPG TR ++ NA I+ +IA +I + K + ++ NPV+
Sbjct: 69 SDLKDYDVVVITAGRPQKPGETRLEMVADNAKIMSNIAKNIKKSGFKGVSIVVANPVD 126
>UniRef50_Q838C9 Cluster: L-lactate dehydrogenase 2; n=9;
Bacilli|Rep: L-lactate dehydrogenase 2 - Enterococcus
faecalis (Streptococcus faecalis)
Length = 317
Score = 48.0 bits (109), Expect = 1e-04
Identities = 24/55 (43%), Positives = 36/55 (65%)
Frame = +1
Query: 352 QDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVN 516
QDAD+VVI AG +KPG +R DL + NA I++ I +I + I+ + +NPV+
Sbjct: 72 QDADIVVITAGANQKPGQSRLDLVSINAEIMKTIVNNIMKSGFDGILVIASNPVD 126
>UniRef50_Q1FID3 Cluster: L-lactate dehydrogenase precursor; n=1;
Clostridium phytofermentans ISDg|Rep: L-lactate
dehydrogenase precursor - Clostridium phytofermentans
ISDg
Length = 325
Score = 47.6 bits (108), Expect = 2e-04
Identities = 26/64 (40%), Positives = 36/64 (56%)
Frame = +1
Query: 328 T*GAISSHQDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITN 507
T G + +DAD+VVI AG P KPG +R D +A IV I + + I ++TN
Sbjct: 66 TEGDYTDCKDADIVVITAGPPPKPGQSRLDTLGLSADIVSTIVEPVMKSGFNGIFLVVTN 125
Query: 508 PVNS 519
PV+S
Sbjct: 126 PVDS 129
>UniRef50_A3DCA4 Cluster: L-lactate dehydrogenase precursor; n=2;
Clostridium|Rep: L-lactate dehydrogenase precursor -
Clostridium thermocellum (strain ATCC 27405 / DSM 1237)
Length = 318
Score = 47.6 bits (108), Expect = 2e-04
Identities = 26/75 (34%), Positives = 39/75 (52%)
Frame = +1
Query: 292 HEHPSQGQRPQGT*GAISSHQDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAX 471
H P GQ G S +D DV+V+ AG RKPG TR DL N I +++ +I
Sbjct: 54 HGLPFMGQMSLYA-GDYSDVKDCDVIVVTAGANRKPGETRLDLAKKNVMIAKEVTQNIMK 112
Query: 472 NAPKAIVDMITNPVN 516
++ +++NPV+
Sbjct: 113 YYNHGVILVVSNPVD 127
>UniRef50_P19869 Cluster: L-lactate dehydrogenase 2; n=17;
Bacteria|Rep: L-lactate dehydrogenase 2 -
Bifidobacterium longum
Length = 320
Score = 47.6 bits (108), Expect = 2e-04
Identities = 24/55 (43%), Positives = 35/55 (63%)
Frame = +1
Query: 352 QDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVN 516
+DAD+VVI AG +KPG +R +L I++ I ++ AP AI +ITNPV+
Sbjct: 75 RDADMVVITAGPRQKPGQSRLELVGATVNILKAIMPNLVKVAPNAIYMLITNPVD 129
>UniRef50_P0A3M9 Cluster: L-lactate dehydrogenase; n=140;
Bacteria|Rep: L-lactate dehydrogenase - Streptococcus
pneumoniae
Length = 328
Score = 47.2 bits (107), Expect = 2e-04
Identities = 24/54 (44%), Positives = 31/54 (57%)
Frame = +1
Query: 355 DADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVN 516
DAD+VVI AG P+KPG TR DL N I + I + + K I + NPV+
Sbjct: 76 DADLVVITAGAPQKPGETRLDLVGKNLAINKSIVTQVVESGFKGIFLVAANPVD 129
>UniRef50_A3JXA9 Cluster: L-lactate dehydrogenase; n=1; Sagittula
stellata E-37|Rep: L-lactate dehydrogenase - Sagittula
stellata E-37
Length = 300
Score = 46.0 bits (104), Expect = 6e-04
Identities = 22/61 (36%), Positives = 35/61 (57%)
Frame = +1
Query: 334 GAISSHQDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPV 513
G ADVV++ GV +KPG +R +L + NA + R + + AP AI+ + +NPV
Sbjct: 51 GGYDDLSGADVVILACGVSQKPGESRLELLSRNAEVFRAVVGDVTRAAPDAILLIASNPV 110
Query: 514 N 516
+
Sbjct: 111 D 111
>UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=1;
Entamoeba histolytica|Rep: NAD-specific malate
dehydrogenase 2 - Entamoeba histolytica
Length = 329
Score = 46.0 bits (104), Expect = 6e-04
Identities = 22/56 (39%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
Frame = +1
Query: 355 DADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAI-VDMITNPVNS 519
+ DV +I AGVPRKPGM R DL N N ++ ++ + K + V ++ NP N+
Sbjct: 87 NVDVAIIVAGVPRKPGMQRSDLINVNKKVMEMNGKALGTYSNKDVRVVVVANPANT 142
>UniRef50_O51114 Cluster: L-lactate dehydrogenase; n=4; Borrelia
burgdorferi group|Rep: L-lactate dehydrogenase -
Borrelia burgdorferi (Lyme disease spirochete)
Length = 316
Score = 46.0 bits (104), Expect = 6e-04
Identities = 23/61 (37%), Positives = 36/61 (59%)
Frame = +1
Query: 334 GAISSHQDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPV 513
G +AD+VVI AG+ +KPG TR DL + N+ I +DI ++ + I + +NPV
Sbjct: 66 GTYKDCANADIVVITAGLNQKPGETRLDLVDKNSKIFKDIITNVVSSGFDGIFVVASNPV 125
Query: 514 N 516
+
Sbjct: 126 D 126
>UniRef50_Q98PG4 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
pulmonis|Rep: L-lactate dehydrogenase - Mycoplasma
pulmonis
Length = 315
Score = 45.6 bits (103), Expect = 8e-04
Identities = 22/70 (31%), Positives = 40/70 (57%)
Frame = +1
Query: 334 GAISSHQDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPV 513
G + + AD++++ AG P+K G TR ++ N+ I++DIAL I + +I+NPV
Sbjct: 63 GTYADAKGADLLIVAAGRPQKQGETRLEMIADNSKIMKDIALEIKKSGFNGFTIVISNPV 122
Query: 514 NSTVPIDSEV 543
+ + +V
Sbjct: 123 DILATVFQKV 132
>UniRef50_P62051 Cluster: L-lactate dehydrogenase; n=2;
Desulfovibrio vulgaris subsp. vulgaris|Rep: L-lactate
dehydrogenase - Desulfovibrio vulgaris (strain
Hildenborough / ATCC 29579 / NCIMB8303)
Length = 309
Score = 45.6 bits (103), Expect = 8e-04
Identities = 23/61 (37%), Positives = 32/61 (52%)
Frame = +1
Query: 334 GAISSHQDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPV 513
G + A +VV+ AG + PG +R DL NA I RDI ++ A + M TNPV
Sbjct: 61 GGYEQCEGARIVVVTAGAKQMPGQSRLDLVRVNAGITRDILTAVMQYADDPLYIMATNPV 120
Query: 514 N 516
+
Sbjct: 121 D 121
>UniRef50_A5KJY5 Cluster: Putative uncharacterized protein; n=2;
Ruminococcus|Rep: Putative uncharacterized protein -
Ruminococcus torques ATCC 27756
Length = 316
Score = 45.2 bits (102), Expect = 0.001
Identities = 24/54 (44%), Positives = 33/54 (61%)
Frame = +1
Query: 355 DADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVN 516
DA VV+I AG +KPG TR DL NA I+R I I + I+ +++NPV+
Sbjct: 71 DASVVIITAGANQKPGETRLDLVQKNAAIMRSIIKEIKRVNCEGILLIVSNPVD 124
>UniRef50_UPI0000DB76D8 Cluster: PREDICTED: similar to CG7998-PA;
n=2; Apis mellifera|Rep: PREDICTED: similar to CG7998-PA
- Apis mellifera
Length = 333
Score = 44.8 bits (101), Expect = 0.001
Identities = 22/50 (44%), Positives = 33/50 (66%)
Frame = +2
Query: 188 GQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEE 337
G L+L LKQ+PL+ LA++D T G+A DL++++T KVS PE+
Sbjct: 13 GNCLSLFLKQSPLIDELAIFDNNSSTYGLALDLNYIDTKCKVSTCNHPEK 62
Score = 36.7 bits (81), Expect = 0.35
Identities = 18/64 (28%), Positives = 38/64 (59%)
Frame = +1
Query: 352 QDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNSTVPI 531
Q A +V+I V + +++ +NA I+ D+ +I +P+A++ ++ NP+NS +P+
Sbjct: 69 QGAKIVMI---VTDRTSNESNEVLKSNAIILSDLLPNIIKFSPQAMLAIVMNPINSLIPL 125
Query: 532 DSEV 543
E+
Sbjct: 126 TMEM 129
>UniRef50_UPI0000D571DB Cluster: PREDICTED: similar to CG7998-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG7998-PA - Tribolium castaneum
Length = 376
Score = 44.8 bits (101), Expect = 0.001
Identities = 21/42 (50%), Positives = 30/42 (71%)
Frame = +1
Query: 418 LFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNSTVPIDSEV 543
LF+ NA IV+D+A SIA +PK+ V + P+NS VP+ SE+
Sbjct: 117 LFDRNAPIVKDLATSIAKFSPKSTVAIGVEPINSVVPMFSEI 158
Score = 39.5 bits (88), Expect = 0.050
Identities = 18/55 (32%), Positives = 35/55 (63%)
Frame = +2
Query: 188 GQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAI 352
G+ ++L+LKQ+P + L LYD + G A DL++++T +V+ G +++ A+
Sbjct: 41 GKSVSLMLKQSPFIDELCLYDTQSL-EGFANDLNYVDTKCRVTSFFGNKDIQKAL 94
>UniRef50_UPI0000D55CD8 Cluster: PREDICTED: similar to Malate
DeHydrogenase family member (mdh-1); n=1; Tribolium
castaneum|Rep: PREDICTED: similar to Malate
DeHydrogenase family member (mdh-1) - Tribolium
castaneum
Length = 374
Score = 44.4 bits (100), Expect = 0.002
Identities = 23/61 (37%), Positives = 36/61 (59%)
Frame = +1
Query: 358 ADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNSTVPIDS 537
A VV+ G KPG ++ +LF+ N VR++A+ +A P+AI + PV + VP+ S
Sbjct: 97 AHVVISTGGCQEKPGSSQRELFDKNLDNVRNVAMFLAEFNPEAIYCIAKPPVEALVPMVS 156
Query: 538 E 540
E
Sbjct: 157 E 157
Score = 33.1 bits (72), Expect = 4.3
Identities = 18/43 (41%), Positives = 25/43 (58%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKV 313
+G LALLLKQN + L L+D T A DL+ ++T K+
Sbjct: 40 VGSNLALLLKQNLDIYELRLFDEENNTNAFACDLNEIDTRTKL 82
>UniRef50_Q87JV1 Cluster: Lactate dehydrogenase; n=4; Vibrio|Rep:
Lactate dehydrogenase - Vibrio parahaemolyticus
Length = 317
Score = 44.4 bits (100), Expect = 0.002
Identities = 23/51 (45%), Positives = 32/51 (62%)
Frame = +1
Query: 358 ADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNP 510
AD+VVI AG + G TR D+ NA I +IA I APKA++ +++NP
Sbjct: 71 ADIVVITAGAQIQQGQTRLDIAEINAKIGVEIARKIERVAPKAVLIVVSNP 121
>UniRef50_Q6F0L9 Cluster: L-lactate dehydrogenase; n=6;
Mollicutes|Rep: L-lactate dehydrogenase - Mesoplasma
florum (Acholeplasma florum)
Length = 317
Score = 44.4 bits (100), Expect = 0.002
Identities = 22/70 (31%), Positives = 39/70 (55%)
Frame = +1
Query: 334 GAISSHQDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPV 513
G +DAD++VI AG P++PG TR +L N+ I++ IA +I + + + +NP
Sbjct: 66 GTYEDCKDADLIVITAGRPQRPGETRLELIADNSRIMKGIAEAIKASGFNGVTVIASNPC 125
Query: 514 NSTVPIDSEV 543
+ + +V
Sbjct: 126 DVLTTVYQQV 135
>UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2;
Ascomycota|Rep: Probable L-lactate dehydrogenase -
Schizosaccharomyces pombe (Fission yeast)
Length = 330
Score = 44.0 bits (99), Expect = 0.002
Identities = 23/55 (41%), Positives = 31/55 (56%)
Frame = +1
Query: 352 QDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVN 516
+DA VVI AG +KPG TR DL N I ++I + AI+ + TNPV+
Sbjct: 86 KDATAVVITAGKNQKPGETRMDLLKANISIFKEILREVTKYTKDAILLVATNPVD 140
>UniRef50_UPI000038D9FF Cluster: COG0039: Malate/lactate
dehydrogenases; n=2; Nostoc punctiforme PCC 73102|Rep:
COG0039: Malate/lactate dehydrogenases - Nostoc
punctiforme PCC 73102
Length = 317
Score = 43.6 bits (98), Expect = 0.003
Identities = 23/55 (41%), Positives = 34/55 (61%), Gaps = 1/55 (1%)
Frame = +1
Query: 355 DADVVVI-PAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVN 516
D+D+++I AGV K G TR D + NA I+R + AP +IV +I+NPV+
Sbjct: 73 DSDIIIIVTAGVQPKLGQTRLDTLSDNAEIIRSTIKELDRVAPNSIVIIISNPVD 127
>UniRef50_Q03BE6 Cluster: L-lactate dehydrogenase; n=1;
Lactobacillus casei ATCC 334|Rep: L-lactate
dehydrogenase - Lactobacillus casei (strain ATCC 334)
Length = 312
Score = 43.6 bits (98), Expect = 0.003
Identities = 20/53 (37%), Positives = 33/53 (62%)
Frame = +1
Query: 358 ADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVN 516
AD++VI AG+ +KPG TR L NA I+++I +I + + + +NPV+
Sbjct: 72 ADIIVITAGIAQKPGQTRLQLLAINAKIMKEITHNIMASGFNGFILVASNPVD 124
>UniRef50_Q8I8U4 Cluster: Lactate dehydrogenase; n=3;
Eimeriorina|Rep: Lactate dehydrogenase - Eimeria tenella
Length = 331
Score = 43.6 bits (98), Expect = 0.003
Identities = 28/77 (36%), Positives = 41/77 (53%), Gaps = 5/77 (6%)
Frame = +1
Query: 310 GQRPQGT*GAISSHQDADVVVIPAGVPRKPG-----MTRDDLFNTNAXIVRDIALSIAXN 474
G R QG + +S + ADVV+I AG+ + G +R DL N I+R++ +I
Sbjct: 63 GVRVQGA-NSYASLEGADVVIITAGITKAAGKSDQEWSRKDLLPVNVKILREVGAAIKQF 121
Query: 475 APKAIVDMITNPVNSTV 525
P A V ITNP++ V
Sbjct: 122 CPHAFVINITNPLDVMV 138
>UniRef50_Q27743 Cluster: L-lactate dehydrogenase; n=17;
Apicomplexa|Rep: L-lactate dehydrogenase - Plasmodium
falciparum (isolate CDC / Honduras)
Length = 316
Score = 43.6 bits (98), Expect = 0.003
Identities = 24/63 (38%), Positives = 35/63 (55%), Gaps = 5/63 (7%)
Frame = +1
Query: 358 ADVVVIPAGVPRKPGMT-----RDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNST 522
ADVV++ AG + PG + RDDL N I+ +I I N P A + ++TNPV+
Sbjct: 73 ADVVIVTAGFTKAPGKSDKEWNRDDLLPLNNKIMIEIGGHIKKNCPNAFIIVVTNPVDVM 132
Query: 523 VPI 531
V +
Sbjct: 133 VQL 135
>UniRef50_A6M0Q2 Cluster: L-lactate dehydrogenase; n=1; Clostridium
beijerinckii NCIMB 8052|Rep: L-lactate dehydrogenase -
Clostridium beijerinckii NCIMB 8052
Length = 316
Score = 42.7 bits (96), Expect = 0.005
Identities = 23/61 (37%), Positives = 33/61 (54%)
Frame = +1
Query: 334 GAISSHQDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPV 513
G DAD+VVI A +P G TR D+ A I+ +I +I + I+ +ITNPV
Sbjct: 66 GEYEECNDADIVVIAAALPYITGQTRLDMLEKAAGIMNNIVPNIMKSGFSGIIVVITNPV 125
Query: 514 N 516
+
Sbjct: 126 D 126
>UniRef50_Q23CW4 Cluster: Malate dehydrogenase, cytoplasmic,
putative; n=3; Oligohymenophorea|Rep: Malate
dehydrogenase, cytoplasmic, putative - Tetrahymena
thermophila SB210
Length = 365
Score = 42.7 bits (96), Expect = 0.005
Identities = 24/64 (37%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Frame = +1
Query: 352 QDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDM-ITNPVNSTVP 528
QD DV V G PRKPGM R DL N I + ++ A K + + NP N+
Sbjct: 119 QDVDVAVFIGGFPRKPGMERKDLLTINGNIFKKQGQALDTVAKKTCKSLVVANPANTNCL 178
Query: 529 IDSE 540
I +E
Sbjct: 179 ILAE 182
>UniRef50_UPI00015B5ACF Cluster: PREDICTED: similar to
ENSANGP00000020184; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000020184 - Nasonia
vitripennis
Length = 352
Score = 41.9 bits (94), Expect = 0.009
Identities = 22/57 (38%), Positives = 34/57 (59%)
Frame = +2
Query: 131 STTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNT 301
++++ RN K G+ LAL LKQ+ L+ LA+YD P T G+ +LSHM++
Sbjct: 29 TSSNSRNLKVAIVGATGQTGRSLALCLKQSALIDELAVYDSHP-TRGLLLELSHMDS 84
>UniRef50_Q2S4R2 Cluster: L-lactate dehydrogenase; n=1; Salinibacter
ruber DSM 13855|Rep: L-lactate dehydrogenase -
Salinibacter ruber (strain DSM 13855)
Length = 316
Score = 41.5 bits (93), Expect = 0.012
Identities = 23/64 (35%), Positives = 37/64 (57%), Gaps = 1/64 (1%)
Frame = +1
Query: 355 DADVVVIPAGVPRK-PGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNSTVPI 531
+A ++V+ AG ++ P TR L NA I R+I + + +AP AI+ + TNPV+ I
Sbjct: 71 NAQIIVLSAGASQQSPDETRLGLLQRNAEIFREIIIQLDKHAPNAILVVATNPVDVLTYI 130
Query: 532 DSEV 543
E+
Sbjct: 131 CQEL 134
>UniRef50_UPI0000D56DC5 Cluster: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor; n=1; Tribolium
castaneum|Rep: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor - Tribolium
castaneum
Length = 349
Score = 41.1 bits (92), Expect = 0.016
Identities = 21/79 (26%), Positives = 42/79 (53%)
Frame = +2
Query: 119 AKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMN 298
+++F + Q++ + +GQ LA L+KQNP ++ L L + V +A D +H +
Sbjct: 11 SRHFCSKPQKHVQVCILGADTLLGQSLAFLIKQNPAISGLHLQGTSKV-ESMALDFNHFD 69
Query: 299 TPAKVSGHKGPEELSAAIK 355
T +V + + +S ++K
Sbjct: 70 TRCRVHSYYDMDSVSKSVK 88
>UniRef50_Q9EVR0 Cluster: L-lactate dehydrogenase; n=1; Selenomonas
ruminantium|Rep: L-lactate dehydrogenase - Selenomonas
ruminantium
Length = 318
Score = 41.1 bits (92), Expect = 0.016
Identities = 22/57 (38%), Positives = 34/57 (59%), Gaps = 2/57 (3%)
Frame = +1
Query: 352 QDADVVVIPAGVPRKPGMTRD--DLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVN 516
+DA+++VI AG +PG T D L TNA I+ + I +A++ MITNP++
Sbjct: 72 KDANIIVITAGPSIRPGETPDRLKLAGTNAKIMSSVMGEIVKRTKEAMIIMITNPLD 128
>UniRef50_Q4Q3J5 Cluster: Malate dehydrogenase, putative; n=5;
Trypanosomatidae|Rep: Malate dehydrogenase, putative -
Leishmania major
Length = 342
Score = 40.7 bits (91), Expect = 0.021
Identities = 26/65 (40%), Positives = 34/65 (52%), Gaps = 4/65 (6%)
Frame = +2
Query: 131 STTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAP----VTPGVAADLSHMN 298
S T+ + K +GQPL+LLLK NP V L + A G+AADLSH++
Sbjct: 8 SLTALKKGKVVLFGCSNAVGQPLSLLLKMNPHVEELVCCNTAADDDVPGSGIAADLSHID 67
Query: 299 TPAKV 313
T KV
Sbjct: 68 TLPKV 72
>UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4;
Bacteroidales|Rep: Malate dehydrogenase - Porphyromonas
gingivalis (Bacteroides gingivalis)
Length = 334
Score = 40.3 bits (90), Expect = 0.028
Identities = 23/57 (40%), Positives = 28/57 (49%), Gaps = 1/57 (1%)
Frame = +1
Query: 355 DADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKA-IVDMITNPVNST 522
DA +V G PRK GMTR+DL NA I + I P V +I NP + T
Sbjct: 74 DAKYIVSSGGAPRKEGMTREDLLKGNAEIAAQLGKDIKSYCPDCKHVIIIFNPADIT 130
>UniRef50_A1U9V0 Cluster: Lactate/malate dehydrogenase; n=6;
Actinomycetales|Rep: Lactate/malate dehydrogenase -
Mycobacterium sp. (strain KMS)
Length = 329
Score = 40.3 bits (90), Expect = 0.028
Identities = 17/51 (33%), Positives = 30/51 (58%)
Frame = +1
Query: 364 VVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVN 516
+VV+ AG + PG +R DL N + + + + ++P A+V +TNPV+
Sbjct: 89 IVVVTAGAKQHPGQSRLDLAAANVAMAQTLTPQLLEHSPDAVVIFVTNPVD 139
>UniRef50_Q6JH30 Cluster: Lactate dehydrogenase; n=3; Plasmodium
(Plasmodium)|Rep: Lactate dehydrogenase - Plasmodium
vivax
Length = 299
Score = 39.9 bits (89), Expect = 0.038
Identities = 23/63 (36%), Positives = 34/63 (53%), Gaps = 5/63 (7%)
Frame = +1
Query: 358 ADVVVIPAGVPRKPGMT-----RDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNST 522
ADVV++ AG + PG + RDDL N I+ +I I P A + ++TNPV+
Sbjct: 66 ADVVIVTAGFTKAPGKSDKEWNRDDLLPLNNKIMIEIGGHIKNLCPNAFIIVVTNPVDVM 125
Query: 523 VPI 531
V +
Sbjct: 126 VQL 128
>UniRef50_Q9PHY2 Cluster: Probable malate dehydrogenase; n=12;
Campylobacter|Rep: Probable malate dehydrogenase -
Campylobacter jejuni
Length = 300
Score = 39.1 bits (87), Expect = 0.066
Identities = 18/55 (32%), Positives = 31/55 (56%)
Frame = +1
Query: 352 QDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVN 516
+++D+V+ AG RK G +R++L N I+ D A I + ++TNPV+
Sbjct: 68 KNSDIVLFSAGFARKDGQSREELLQLNTSIMLDCAKKIKDFTEDPLFIILTNPVD 122
>UniRef50_Q1IRL5 Cluster: L-lactate dehydrogenase; n=6;
Bacteria|Rep: L-lactate dehydrogenase - Acidobacteria
bacterium (strain Ellin345)
Length = 321
Score = 38.7 bits (86), Expect = 0.087
Identities = 20/61 (32%), Positives = 32/61 (52%)
Frame = +1
Query: 334 GAISSHQDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPV 513
G + + A V VI AG ++PG TR L + N I + I + + P ++ + TNPV
Sbjct: 70 GEYADCRGAAVTVITAGAAQRPGETRLQLLDRNLAIFQQIVPEVVKHNPDGLLLIATNPV 129
Query: 514 N 516
+
Sbjct: 130 D 130
>UniRef50_A4A2L6 Cluster: L-lactate dehydrogenase; n=4;
Bacteria|Rep: L-lactate dehydrogenase - Blastopirellula
marina DSM 3645
Length = 313
Score = 38.7 bits (86), Expect = 0.087
Identities = 24/65 (36%), Positives = 34/65 (52%), Gaps = 2/65 (3%)
Frame = +1
Query: 328 T*GAISSHQDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPK--AIVDMI 501
T G D+DV+ I AG+ RKP +R DL N N + I S+ K AI ++
Sbjct: 59 TSGGYEHIPDSDVICITAGLRRKPDESRLDLINRNVDLFLSILDSVKSAGVKKDAICFVV 118
Query: 502 TNPVN 516
+NPV+
Sbjct: 119 SNPVD 123
>UniRef50_Q4UJ29 Cluster: L-lactate dehydrogenase, putative; n=2;
Theileria|Rep: L-lactate dehydrogenase, putative -
Theileria annulata
Length = 367
Score = 38.7 bits (86), Expect = 0.087
Identities = 18/39 (46%), Positives = 26/39 (66%)
Frame = +1
Query: 409 RDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNSTV 525
RDDL N+ I+RD+ +I AP+A V +ITNP++ V
Sbjct: 143 RDDLVGYNSKIIRDVGENIKKYAPEAFVIVITNPMDVMV 181
>UniRef50_P20619 Cluster: L-lactate dehydrogenase X; n=14;
Bacillales|Rep: L-lactate dehydrogenase X - Bacillus
psychrosaccharolyticus
Length = 319
Score = 38.3 bits (85), Expect = 0.11
Identities = 20/55 (36%), Positives = 30/55 (54%)
Frame = +1
Query: 352 QDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVN 516
++AD+V I AG +KPG TR DL N I + + + + I + TNPV+
Sbjct: 73 KEADIVCICAGANQKPGETRLDLVEKNLKIFKSLVDQVMASGFDGIFLIATNPVD 127
>UniRef50_A2UB98 Cluster: Lactate/malate dehydrogenase precursor;
n=2; Bacteria|Rep: Lactate/malate dehydrogenase
precursor - Bacillus coagulans 36D1
Length = 327
Score = 37.9 bits (84), Expect = 0.15
Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 5/71 (7%)
Frame = +1
Query: 334 GAISSHQDADVVVIPAGVPRKPGMT-----RDDLFNTNAXIVRDIALSIAXNAPKAIVDM 498
G S DADV++ AG P R L TNA +VR++ I +A++
Sbjct: 65 GDYSECADADVIICAAGPSVLPSEKDEMPDRAGLARTNAAVVREVMAGITKYTKEAVIIF 124
Query: 499 ITNPVNSTVPI 531
ITNP+++ V I
Sbjct: 125 ITNPLDTIVYI 135
>UniRef50_A0D8T3 Cluster: Malate dehydrogenase; n=2; Paramecium
tetraurelia|Rep: Malate dehydrogenase - Paramecium
tetraurelia
Length = 322
Score = 37.5 bits (83), Expect = 0.20
Identities = 20/57 (35%), Positives = 28/57 (49%), Gaps = 1/57 (1%)
Frame = +1
Query: 352 QDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAI-VDMITNPVNS 519
+DADV + +PRKPGM R DL N I + A + V ++ NP N+
Sbjct: 81 KDADVAIFLGAMPRKPGMERSDLLQMNREIFIQQGQILNEQAKSTVKVLVVANPSNT 137
>UniRef50_Q4JY42 Cluster: L-lactate dehydrogenase; n=1;
Corynebacterium jeikeium K411|Rep: L-lactate
dehydrogenase - Corynebacterium jeikeium (strain K411)
Length = 326
Score = 37.5 bits (83), Expect = 0.20
Identities = 24/75 (32%), Positives = 34/75 (45%)
Frame = +1
Query: 292 HEHPSQGQRPQGT*GAISSHQDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAX 471
H P + T G +DA +V I AG +KPG TR DL N I + I +
Sbjct: 62 HAVPWSHHNTRVTVGTYEDCRDAAMVCICAGAAQKPGETRLDLVAKNTAIFKTIVGDVMS 121
Query: 472 NAPKAIVDMITNPVN 516
+ I + +NPV+
Sbjct: 122 HGFNGIFLVASNPVD 136
>UniRef50_Q9P4B6 Cluster: L-lactate dehydrogenase A; n=48; Rhizopus
oryzae|Rep: L-lactate dehydrogenase A - Rhizopus oryzae
(Rhizopus delemar)
Length = 320
Score = 37.1 bits (82), Expect = 0.26
Identities = 18/61 (29%), Positives = 31/61 (50%)
Frame = +1
Query: 334 GAISSHQDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPV 513
G+ AD+VVI AG ++ G R L N +++ I + P A++ ++ NPV
Sbjct: 63 GSAEEAGQADIVVITAGAKQREGEPRTKLIERNFRVLQSIIGGMQPIRPDAVILVVANPV 122
Query: 514 N 516
+
Sbjct: 123 D 123
>UniRef50_Q81XJ7 Cluster: L-lactate dehydrogenase 3; n=13;
Firmicutes|Rep: L-lactate dehydrogenase 3 - Bacillus
anthracis
Length = 316
Score = 37.1 bits (82), Expect = 0.26
Identities = 18/61 (29%), Positives = 31/61 (50%)
Frame = +1
Query: 334 GAISSHQDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPV 513
G+ +D D+V+I AG KPG +R D +A I+ + + + I + +NPV
Sbjct: 66 GSYEDCKDMDIVIITAGPAPKPGQSRLDTLGASAKIMESVVGGVMESGFDGIFLLASNPV 125
Query: 514 N 516
+
Sbjct: 126 D 126
>UniRef50_Q017A7 Cluster: Chromosome 06 contig 1, DNA sequence; n=1;
Ostreococcus tauri|Rep: Chromosome 06 contig 1, DNA
sequence - Ostreococcus tauri
Length = 131
Score = 36.3 bits (80), Expect = 0.46
Identities = 17/28 (60%), Positives = 19/28 (67%)
Frame = -3
Query: 348 AADSSSGPLWPLTLAGVFMWERSAATPG 265
AA SS+ P +P T A VF E SAATPG
Sbjct: 10 AAPSSASPAYPFTCAAVFTCETSAATPG 37
>UniRef50_P61973 Cluster: Malate dehydrogenase; n=43; Bacteria|Rep:
Malate dehydrogenase - Bdellovibrio bacteriovorus
Length = 335
Score = 36.3 bits (80), Expect = 0.46
Identities = 22/61 (36%), Positives = 29/61 (47%), Gaps = 1/61 (1%)
Frame = +1
Query: 352 QDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNA-PKAIVDMITNPVNSTVP 528
+DADV ++ PR PGM R DL N I +I A P V ++ NP N+
Sbjct: 81 KDADVALLVGARPRGPGMERKDLLTANGQIFTVQGEAIGKYANPNVKVLVVGNPANTNAY 140
Query: 529 I 531
I
Sbjct: 141 I 141
>UniRef50_UPI0001554DCB Cluster: PREDICTED: similar to Zinc finger
protein 160, partial; n=1; Ornithorhynchus anatinus|Rep:
PREDICTED: similar to Zinc finger protein 160, partial -
Ornithorhynchus anatinus
Length = 912
Score = 35.5 bits (78), Expect = 0.81
Identities = 17/43 (39%), Positives = 21/43 (48%)
Frame = +1
Query: 199 GPSTEAESSGDQAGFIRHSACDPRRRSRPFPHEHPSQGQRPQG 327
GP S G G +R+SA DP RRS P P +R +G
Sbjct: 143 GPGEPVRSGGAGEGAVRNSALDPTRRSHPSPIPPRGSRERDEG 185
>UniRef50_Q0UX88 Cluster: L-lactate dehydrogenase; n=2;
Phaeosphaeria nodorum|Rep: L-lactate dehydrogenase -
Phaeosphaeria nodorum (Septoria nodorum)
Length = 326
Score = 35.1 bits (77), Expect = 1.1
Identities = 21/63 (33%), Positives = 34/63 (53%), Gaps = 3/63 (4%)
Frame = +1
Query: 346 SHQDA---DVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVN 516
+HQ+A D+VVI AG +K G +R L N I+ I S+ + ++ ++ NPV+
Sbjct: 66 THQEAGQADIVVITAGAKQKTGESRLSLLTRNLNILSSIFDSMKPISAHTVLLLVANPVD 125
Query: 517 STV 525
V
Sbjct: 126 ILV 128
>UniRef50_A2QJT7 Cluster: Catalytic activity: precursor; n=1;
Aspergillus niger|Rep: Catalytic activity: precursor -
Aspergillus niger
Length = 307
Score = 35.1 bits (77), Expect = 1.1
Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 3/70 (4%)
Frame = +1
Query: 343 SSHQDA---DVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPV 513
++HQ+A DVV+I AGV PG T I++ I + P AI+ ++ NPV
Sbjct: 62 ATHQEASQADVVIITAGVNYTPGETTLQHLYHKFSILKSILNEMRPFNPNAIILVVANPV 121
Query: 514 NSTVPIDSEV 543
++ + ++
Sbjct: 122 DTLTTLAQDI 131
>UniRef50_Q0PQR8 Cluster: Malate dehydrogenase NAD-dependent; n=1;
Endoriftia persephone 'Hot96_1+Hot96_2'|Rep: Malate
dehydrogenase NAD-dependent - Endoriftia persephone
'Hot96_1+Hot96_2'
Length = 170
Score = 34.7 bits (76), Expect = 1.4
Identities = 14/38 (36%), Positives = 24/38 (63%)
Frame = +1
Query: 412 DDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNSTV 525
DDL + N + + +A ++ +AP A V + TNP++S V
Sbjct: 16 DDLLDINLSVTKKVATAVKQHAPDAFVILTTNPLDSIV 53
>UniRef50_O61865 Cluster: Putative uncharacterized protein; n=9;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 488
Score = 34.3 bits (75), Expect = 1.9
Identities = 16/38 (42%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
Frame = -3
Query: 114 FCTARAAGFRARENIFVVC-LTCIYVYI*TIST*PSRP 4
FC+ R F R +F+ C LTC+Y + IST P+ P
Sbjct: 320 FCSKRIKNFGMRPTMFIGCFLTCLYCALVVISTPPTAP 357
>UniRef50_A3CTN0 Cluster: Lactate/malate dehydrogenase; n=1;
Methanoculleus marisnigri JR1|Rep: Lactate/malate
dehydrogenase - Methanoculleus marisnigri (strain ATCC
35101 / DSM 1498 / JR1)
Length = 288
Score = 34.3 bits (75), Expect = 1.9
Identities = 18/57 (31%), Positives = 31/57 (54%), Gaps = 1/57 (1%)
Frame = +1
Query: 352 QDADVVVIPAGVPRKPGM-TRDDLFNTNAXIVRDIALSIAXNAPKAIVDMITNPVNS 519
+DAD+ V AG PR P + TR DL N + + + + P ++ +TNP+++
Sbjct: 63 RDADIFVFAAGTPRTPDIKTRADLLEANIPVAKRCS-ELLEGFPGVVIS-VTNPMDA 117
>UniRef50_Q97DC6 Cluster: L-lactate dehydrogenase 2; n=1;
Clostridium acetobutylicum|Rep: L-lactate dehydrogenase
2 - Clostridium acetobutylicum
Length = 320
Score = 34.3 bits (75), Expect = 1.9
Identities = 20/56 (35%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
Frame = +1
Query: 355 DADVVVIPAGVPRKPGMTRDDLF--NTNAXIVRDIALSIAXNAPKAIVDMITNPVN 516
DA ++VI AG KP D L +TN + I +I AI+ ++TNPV+
Sbjct: 74 DAQIIVITAGPSLKPDDKLDRLVLADTNVKVTDSIMKNICKYTKDAIIIVVTNPVD 129
>UniRef50_UPI0000DD82B5 Cluster: PREDICTED: hypothetical protein;
n=1; Homo sapiens|Rep: PREDICTED: hypothetical protein -
Homo sapiens
Length = 258
Score = 33.9 bits (74), Expect = 2.5
Identities = 20/41 (48%), Positives = 20/41 (48%), Gaps = 1/41 (2%)
Frame = +1
Query: 217 ESSGDQAGFIRHSACDPRRRSRPFPHE-HPSQGQRPQGT*G 336
E GDQ RH AC R S P E P GQRP GT G
Sbjct: 6 EGRGDQERTRRHRACPGCRGSEVSPGEGAPGSGQRPAGTSG 46
>UniRef50_Q4S3J0 Cluster: Chromosome 1 SCAF14749, whole genome
shotgun sequence; n=2; Tetraodon nigroviridis|Rep:
Chromosome 1 SCAF14749, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 778
Score = 33.5 bits (73), Expect = 3.3
Identities = 18/47 (38%), Positives = 21/47 (44%)
Frame = +1
Query: 160 GGRWCRRWYRPAFGPSTEAESSGDQAGFIRHSACDPRRRSRPFPHEH 300
G R R + P GP E G Q +RH A P RR R P +H
Sbjct: 554 GVRAPRGLHHPGAGPQRAHEGRGRQPAAVRHPAEPPGRRHRERPGDH 600
>UniRef50_Q64YY6 Cluster: Malate dehydrogenase; n=5;
Bacteroidales|Rep: Malate dehydrogenase - Bacteroides
fragilis
Length = 333
Score = 33.5 bits (73), Expect = 3.3
Identities = 20/56 (35%), Positives = 25/56 (44%), Gaps = 1/56 (1%)
Frame = +1
Query: 358 ADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKA-IVDMITNPVNST 522
A +V G RK GMTR+DL NA I I P V ++ NP + T
Sbjct: 75 AKYIVSSGGAARKAGMTREDLLKGNAEIAAQFGKDIRQYCPDVKHVVVVFNPADIT 130
>UniRef50_Q9GPV2 Cluster: Cytosolic malate dehydrogenase; n=4;
Trichomonadida|Rep: Cytosolic malate dehydrogenase -
Tetratrichomonas gallinarum
Length = 314
Score = 33.1 bits (72), Expect = 4.3
Identities = 19/57 (33%), Positives = 28/57 (49%), Gaps = 1/57 (1%)
Frame = +1
Query: 352 QDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAI-VDMITNPVNS 519
+D DV + PRK GM R DL N I +++ A K + V ++ NP N+
Sbjct: 60 KDVDVAFLVGSFPRKDGMDRSDLLAKNGGIFTVQGKALSDFAKKDVKVLVVGNPANT 116
>UniRef50_UPI00015B4591 Cluster: PREDICTED: similar to mitochondrial
malate dehydrogenase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to mitochondrial malate dehydrogenase
- Nasonia vitripennis
Length = 299
Score = 32.7 bits (71), Expect = 5.7
Identities = 14/41 (34%), Positives = 26/41 (63%)
Frame = +1
Query: 421 FNTNAXIVRDIALSIAXNAPKAIVDMITNPVNSTVPIDSEV 543
F ++ V+ +A + PKA+V + T+PV +T+P+ SE+
Sbjct: 74 FVNSSNYVKSVAECMINVCPKALVAVFTHPVTATLPLVSEI 114
>UniRef50_Q8NHM5 Cluster: JmjC domain-containing histone
demethylation protein 1B; n=56; Euteleostomi|Rep: JmjC
domain-containing histone demethylation protein 1B -
Homo sapiens (Human)
Length = 1336
Score = 32.7 bits (71), Expect = 5.7
Identities = 14/22 (63%), Positives = 16/22 (72%)
Frame = -1
Query: 167 RPPL*SSSVMWWKSSLHHFVQQ 102
RPPL SS WW+SSL +F QQ
Sbjct: 834 RPPLGSSLSPWWRSSLTYFQQQ 855
>UniRef50_UPI0000DD849E Cluster: PREDICTED: hypothetical protein;
n=1; Homo sapiens|Rep: PREDICTED: hypothetical protein -
Homo sapiens
Length = 431
Score = 32.3 bits (70), Expect = 7.5
Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 5/115 (4%)
Frame = +1
Query: 70 NVLPRPKT-CRPCCTKWCKELFHHITEEL*SGGRWC----RRWYRPAFGPSTEAESSGDQ 234
N+ PRP T C CT+ H E GR C +R +R P + ++SG
Sbjct: 160 NISPRPPTSCPSSCTQRGDSAGHQTAE-----GRRCLQPSQRGWRTR--PDSHRKNSGVG 212
Query: 235 AGFIRHSACDPRRRSRPFPHEHPSQGQRPQGT*GAISSHQDADVVVIPAGVPRKP 399
G IR + P E PS+ + P + GA+++ Q+ PA P++P
Sbjct: 213 RGQIRLARKSFSDTLASAPKERPSRTRSPGSSRGAVATAQE------PAASPKEP 261
>UniRef50_Q6ABA1 Cluster: DNA polymerase III subunit gamma; n=2;
cellular organisms|Rep: DNA polymerase III subunit gamma
- Propionibacterium acnes
Length = 957
Score = 32.3 bits (70), Expect = 7.5
Identities = 13/22 (59%), Positives = 15/22 (68%)
Frame = +1
Query: 262 DPRRRSRPFPHEHPSQGQRPQG 327
+P RRS P H+ PS GQRP G
Sbjct: 534 NPERRSAPEHHDAPSPGQRPSG 555
>UniRef50_P83778 Cluster: Malate dehydrogenase, cytoplasmic; n=1;
Candida albicans|Rep: Malate dehydrogenase, cytoplasmic
- Candida albicans (Yeast)
Length = 51
Score = 32.3 bits (70), Expect = 7.5
Identities = 18/29 (62%), Positives = 21/29 (72%)
Frame = +2
Query: 227 VTRLALYDIAPVTPGVAADLSHMNTPAKV 313
VT LALYDI P GVAAD+SH+ T + V
Sbjct: 1 VTDLALYDIRP---GVAADVSHVPTNSTV 26
>UniRef50_UPI000023EEAF Cluster: hypothetical protein FG02077.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG02077.1 - Gibberella zeae PH-1
Length = 184
Score = 31.9 bits (69), Expect = 9.9
Identities = 15/40 (37%), Positives = 22/40 (55%)
Frame = +2
Query: 230 TRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAA 349
T A +AP+ P AA+ +TPA + KGPE+ + A
Sbjct: 126 TAAATTTVAPIIPTTAAEEPATSTPAAATPTKGPEQANGA 165
>UniRef50_Q3MGZ6 Cluster: Putative uncharacterized protein
precursor; n=1; Anabaena variabilis ATCC 29413|Rep:
Putative uncharacterized protein precursor - Anabaena
variabilis (strain ATCC 29413 / PCC 7937)
Length = 303
Score = 31.9 bits (69), Expect = 9.9
Identities = 18/51 (35%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
Frame = +1
Query: 370 VIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAIVDM-ITNPVNS 519
++P G P KP T D+ +T + + L NA KAI+++ NPVN+
Sbjct: 116 LVPEG-PSKPNPTAQDIVSTLGNLNLNSILVTRENADKAIIEVSFANPVNT 165
>UniRef50_A5CM82 Cluster: Putative uncharacterized protein; n=1;
Clavibacter michiganensis subsp. michiganensis NCPPB
382|Rep: Putative uncharacterized protein - Clavibacter
michiganensis subsp. michiganensis (strain NCPPB 382)
Length = 210
Score = 31.9 bits (69), Expect = 9.9
Identities = 15/58 (25%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Frame = -3
Query: 378 WDDYNISILMAADSS-SGPLWPLTLAGVFMWERSAATPGVTGAMSYKASLVTRGFCFS 208
W D ++I D++ SG W +T+ +WER++ P + + +TR F+
Sbjct: 127 WSDDRLAIQTKGDNNPSGDPWIVTIGDDAVWERTSVVPFLGWPFVWLGDPITRAIAFA 184
>UniRef50_Q47706 Cluster: Membrane-associated protein uidC
precursor; n=22; Enterobacteriaceae|Rep:
Membrane-associated protein uidC precursor - Escherichia
coli (strain K12)
Length = 421
Score = 31.9 bits (69), Expect = 9.9
Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Frame = +3
Query: 99 PLLYKMVQRTFPPHHRGTLKWWSLVPPVVSASLWPFY*SRI-LW 227
PL+ QRT P G L +W+L P + LW + SR+ LW
Sbjct: 141 PLMAGSSQRTLPTVSEGALGYWALTPNI---DLWGMWRSRVFLW 181
>UniRef50_P55735 Cluster: Protein SEC13 homolog; n=84;
Eukaryota|Rep: Protein SEC13 homolog - Homo sapiens
(Human)
Length = 322
Score = 31.9 bits (69), Expect = 9.9
Identities = 13/41 (31%), Positives = 19/41 (46%)
Frame = -3
Query: 408 GHSRFTGYSCWDDYNISILMAADSSSGPLWPLTLAGVFMWE 286
GH CW ++ +++A SS G + LT G WE
Sbjct: 101 GHDSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGEGQWE 141
>UniRef50_Q9Z6N1 Cluster: Malate dehydrogenase; n=8;
Chlamydiaceae|Rep: Malate dehydrogenase - Chlamydia
pneumoniae (Chlamydophila pneumoniae)
Length = 328
Score = 31.9 bits (69), Expect = 9.9
Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
Frame = +1
Query: 361 DVVVIPAGVPRKPGMTRDDLFNTNAXI--VRDIALSIAXNAPKAIVDMITNPVNS 519
D + VPR PGM R DL N I ++ AL+ A A + ++ NPVN+
Sbjct: 84 DAAFLIGAVPRGPGMERGDLLKQNGQIFSLQGAALNTAAKR-DAKIFVVGNPVNT 137
>UniRef50_A1W9K7 Cluster: Malate dehydrogenase; n=95; cellular
organisms|Rep: Malate dehydrogenase - Acidovorax sp.
(strain JS42)
Length = 328
Score = 31.9 bits (69), Expect = 9.9
Identities = 19/65 (29%), Positives = 32/65 (49%), Gaps = 1/65 (1%)
Frame = +1
Query: 340 ISSHQDADVVVIPAGVPRKPGMTRDDLFNTNAXIVRDIALSIAXNAPKAI-VDMITNPVN 516
+++ +D D ++ PR PGM R DL NA I ++ A + + V ++ NP N
Sbjct: 78 MTAFKDTDYALLVGARPRGPGMERADLLAANAQIFTAQGKALNAVASRNVKVLVVGNPAN 137
Query: 517 STVPI 531
+ I
Sbjct: 138 TNAYI 142
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 558,815,626
Number of Sequences: 1657284
Number of extensions: 12333344
Number of successful extensions: 34627
Number of sequences better than 10.0: 136
Number of HSP's better than 10.0 without gapping: 33103
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 34574
length of database: 575,637,011
effective HSP length: 96
effective length of database: 416,537,747
effective search space used: 35405708495
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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