Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Nnor0154
(695 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 81 4e-15
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 79 1e-14
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 79 1e-14
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 79 1e-14
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 79 1e-14
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 79 1e-14
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 79 1e-14
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 75 3e-13
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 73 1e-12
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 73 1e-12
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 73 1e-12
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 73 1e-12
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 72 2e-12
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 72 2e-12
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 72 2e-12
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 72 2e-12
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 72 2e-12
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 72 2e-12
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 72 2e-12
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 72 2e-12
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 71 3e-12
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 71 3e-12
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 71 3e-12
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 71 3e-12
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 71 3e-12
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 71 3e-12
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 71 3e-12
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 71 3e-12
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 71 3e-12
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 71 3e-12
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 71 3e-12
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 71 3e-12
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 71 5e-12
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 70 7e-12
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 70 7e-12
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 70 9e-12
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 70 9e-12
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 70 9e-12
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 70 9e-12
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 69 1e-11
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 69 1e-11
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 69 1e-11
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 69 1e-11
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 69 1e-11
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 69 1e-11
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 69 1e-11
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 69 2e-11
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 69 2e-11
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 69 2e-11
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 69 2e-11
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 69 2e-11
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 69 2e-11
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 69 2e-11
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 69 2e-11
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 69 2e-11
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 65 3e-10
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 65 3e-10
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 65 3e-10
DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit ... 64 3e-10
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 64 3e-10
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 64 3e-10
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 64 3e-10
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 64 6e-10
X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor ep... 63 8e-10
AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor ... 63 8e-10
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 63 1e-09
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 63 1e-09
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 63 1e-09
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 63 1e-09
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 63 1e-09
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 63 1e-09
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 62 1e-09
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 62 1e-09
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 62 1e-09
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 62 1e-09
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 62 1e-09
BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor, n... 60 6e-09
BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor, n... 60 6e-09
AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine... 60 6e-09
AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine... 60 6e-09
AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine... 60 6e-09
AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein. 60 6e-09
AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic acet... 60 1e-08
AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic acet... 60 1e-08
AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine... 60 1e-08
AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine... 60 1e-08
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 56 9e-08
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 56 9e-08
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 56 9e-08
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 56 9e-08
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 56 9e-08
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 56 9e-08
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 56 9e-08
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 56 9e-08
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 56 9e-08
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 55 2e-07
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 55 2e-07
S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2 sub... 55 3e-07
S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2 sub... 55 3e-07
S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A... 55 3e-07
BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein. 55 3e-07
BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein. 55 3e-07
BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein. 55 3e-07
M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid r... 54 4e-07
BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channe... 54 4e-07
AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channe... 54 4e-07
L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine recep... 54 5e-07
BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid... 54 5e-07
BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid... 54 5e-07
BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid... 54 5e-07
AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channe... 54 5e-07
X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1 su... 54 6e-07
BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein. 53 9e-07
S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type ... 52 1e-06
AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor prot... 52 1e-06
D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor ... 52 3e-06
BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine (se... 52 3e-06
BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine (se... 52 3e-06
BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine (se... 52 3e-06
AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor pr... 52 3e-06
AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3 re... 52 3e-06
AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor prot... 52 3e-06
AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine rec... 52 3e-06
BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid... 51 3e-06
AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa) (... 51 3e-06
S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3 su... 51 5e-06
S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA ... 51 5e-06
AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3 ... 51 5e-06
AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3 ... 51 5e-06
AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit a... 51 5e-06
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 50 8e-06
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 50 8e-06
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 50 8e-06
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 50 1e-05
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 50 1e-05
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 50 1e-05
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 50 1e-05
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 50 1e-05
S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid t... 49 1e-05
BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid... 49 1e-05
BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid... 49 1e-05
BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid... 49 1e-05
BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid... 49 1e-05
BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid... 49 1e-05
U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit al... 48 2e-05
BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid... 48 2e-05
U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subuni... 47 7e-05
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 47 7e-05
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 47 7e-05
BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid... 47 7e-05
BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid... 47 7e-05
BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein. 47 7e-05
BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein. 47 7e-05
BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid... 47 7e-05
BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid... 47 7e-05
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 47 7e-05
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 47 7e-05
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 47 7e-05
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 47 7e-05
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 47 7e-05
AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subu... 47 7e-05
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 46 1e-04
BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid... 46 1e-04
BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid... 46 1e-04
BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid... 46 1e-04
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 46 1e-04
AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid... 46 1e-04
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 46 1e-04
X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2 s... 45 2e-04
BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid... 45 2e-04
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 45 3e-04
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 45 3e-04
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 45 3e-04
AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor, n... 44 5e-04
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 44 7e-04
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 44 7e-04
BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein. 43 0.001
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 42 0.002
BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein. 31 5.2
AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled recep... 31 5.2
AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein. 31 5.2
AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marke... 31 5.2
AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein. 31 5.2
U90661-1|AAB50242.1| 1441|Homo sapiens steroid receptor coactiva... 30 9.1
U59302-1|AAC50631.1| 1440|Homo sapiens steroid receptor coactiva... 30 9.1
U40396-1|AAC50305.1| 1061|Homo sapiens steroid receptor coactiva... 30 9.1
EF660499-1|ABS29266.1| 1441|Homo sapiens nuclear receptor coacti... 30 9.1
BC111534-1|AAI11535.1| 1399|Homo sapiens nuclear receptor coacti... 30 9.1
BC111533-1|AAI11534.1| 1441|Homo sapiens nuclear receptor coacti... 30 9.1
BC039695-1|AAH39695.1| 1129|Homo sapiens JAK2 protein protein. 30 9.1
AY973034-1|AAY22962.1| 1132|Homo sapiens Janus kinase 2 protein. 30 9.1
AL161450-1|CAD13329.1| 1132|Homo sapiens Janus kinase 2 (a prote... 30 9.1
AK093764-1|BAC04222.1| 360|Homo sapiens protein ( Homo sapiens ... 30 9.1
AJ000882-1|CAA04372.1| 1399|Homo sapiens steroid receptor coacti... 30 9.1
AJ000881-1|CAA04371.1| 1441|Homo sapiens steroid receptor coacti... 30 9.1
AF058925-1|AAC23982.1| 1132|Homo sapiens Jak2 kinase protein. 30 9.1
AF005216-1|AAB82092.1| 1132|Homo sapiens receptor-associated tyr... 30 9.1
AF001362-1|AAC23653.1| 1132|Homo sapiens Jak2 kinase protein. 30 9.1
AC013459-1|AAX93184.1| 1441|Homo sapiens unknown protein. 30 9.1
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 81.0 bits (191), Expect = 4e-15
Identities = 61/215 (28%), Positives = 98/215 (45%), Gaps = 13/215 (6%)
Frame = +1
Query: 16 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 177
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 178 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 351
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNDGTYE 125
Query: 352 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVID 531
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 126 VSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLM 185
Query: 532 KRIYSMFE---SGAWDVTDLSS--AVQSQDRGEVE 621
SM + SG WD+ L V QD V+
Sbjct: 186 TPTASMDDFTPSGEWDIVALPGRRTVNPQDPSYVD 220
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 79.0 bits (186), Expect = 1e-14
Identities = 62/216 (28%), Positives = 99/216 (45%), Gaps = 14/216 (6%)
Frame = +1
Query: 16 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 177
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 178 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATT 348
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 349 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 528
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
Query: 529 DKRIYSMFE---SGAWDVTDLSS--AVQSQDRGEVE 621
SM + SG WD+ L V QD V+
Sbjct: 186 MTPTASMDDFTPSGEWDIVALPGRRTVNPQDPSYVD 221
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 79.0 bits (186), Expect = 1e-14
Identities = 62/216 (28%), Positives = 99/216 (45%), Gaps = 14/216 (6%)
Frame = +1
Query: 16 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 177
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 178 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATT 348
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 349 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 528
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
Query: 529 DKRIYSMFE---SGAWDVTDLSS--AVQSQDRGEVE 621
SM + SG WD+ L V QD V+
Sbjct: 186 MTPTASMDDFTPSGEWDIVALPGRRTVNPQDPSYVD 221
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 79.0 bits (186), Expect = 1e-14
Identities = 62/216 (28%), Positives = 99/216 (45%), Gaps = 14/216 (6%)
Frame = +1
Query: 16 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 177
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 178 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATT 348
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 349 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 528
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
Query: 529 DKRIYSMFE---SGAWDVTDLSS--AVQSQDRGEVE 621
SM + SG WD+ L V QD V+
Sbjct: 186 MTPTASMDDFTPSGEWDIVALPGRRTVNPQDPSYVD 221
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 79.0 bits (186), Expect = 1e-14
Identities = 62/216 (28%), Positives = 99/216 (45%), Gaps = 14/216 (6%)
Frame = +1
Query: 16 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 177
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 178 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATT 348
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 349 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 528
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
Query: 529 DKRIYSMFE---SGAWDVTDLSS--AVQSQDRGEVE 621
SM + SG WD+ L V QD V+
Sbjct: 186 MTPTASMDDFTPSGEWDIVALPGRRTVNPQDPSYVD 221
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 79.0 bits (186), Expect = 1e-14
Identities = 62/216 (28%), Positives = 99/216 (45%), Gaps = 14/216 (6%)
Frame = +1
Query: 16 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 177
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 178 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATT 348
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 349 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 528
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
Query: 529 DKRIYSMFE---SGAWDVTDLSS--AVQSQDRGEVE 621
SM + SG WD+ L V QD V+
Sbjct: 186 MTPTASMDDFTPSGEWDIVALPGRRTVNPQDPSYVD 221
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 79.0 bits (186), Expect = 1e-14
Identities = 62/216 (28%), Positives = 99/216 (45%), Gaps = 14/216 (6%)
Frame = +1
Query: 16 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 177
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 178 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATT 348
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTY 125
Query: 349 AGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI 528
V +NGSV W+ + +++ +P D Q CT KF S ++ E+D V+
Sbjct: 126 EVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
Query: 529 DKRIYSMFE---SGAWDVTDLSS--AVQSQDRGEVE 621
SM + SG WD+ L V QD V+
Sbjct: 186 MTPTASMDDFTPSGEWDIVALPGRRTVNPQDPSYVD 221
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 74.5 bits (175), Expect = 3e-13
Identities = 50/168 (29%), Positives = 79/168 (47%), Gaps = 8/168 (4%)
Frame = +1
Query: 142 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 315
I + L L L ++ E + + L+ W D RL+WN+ + G + + ++R+W P
Sbjct: 7 ISIKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 66
Query: 316 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 492
D+VL N A T V +NGSV W+ + +++ +P D Q CT KF S
Sbjct: 67 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 126
Query: 493 RMHNSDEMDFVIDKRIYSMFE---SGAWDVTDLSS--AVQSQDRGEVE 621
++ E+D V+ SM + SG WD+ L V QD V+
Sbjct: 127 WTYDHTEIDMVLMTPTASMDDFTPSGEWDIVALPGRRTVNPQDPSYVD 174
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 72.9 bits (171), Expect = 1e-12
Identities = 43/179 (24%), Positives = 85/179 (47%), Gaps = 11/179 (6%)
Frame = +1
Query: 88 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 252
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 253 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 429
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 430 ISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-----IDKRIYSMFESGAWDVTDLSSA 591
++ + +P D+Q C+ KFGS ++ ++D + +DKR F++G W++ + +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKR--DFFDNGEWEIVSATGS 226
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 72.9 bits (171), Expect = 1e-12
Identities = 43/179 (24%), Positives = 85/179 (47%), Gaps = 11/179 (6%)
Frame = +1
Query: 88 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 252
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 253 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 429
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 430 ISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-----IDKRIYSMFESGAWDVTDLSSA 591
++ + +P D+Q C+ KFGS ++ ++D + +DKR F++G W++ + +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKR--DFFDNGEWEIVSATGS 226
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 72.9 bits (171), Expect = 1e-12
Identities = 43/179 (24%), Positives = 85/179 (47%), Gaps = 11/179 (6%)
Frame = +1
Query: 88 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 252
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 253 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 429
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 430 ISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-----IDKRIYSMFESGAWDVTDLSSA 591
++ + +P D+Q C+ KFGS ++ ++D + +DKR F++G W++ + +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKR--DFFDNGEWEIVSATGS 226
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 72.9 bits (171), Expect = 1e-12
Identities = 43/179 (24%), Positives = 85/179 (47%), Gaps = 11/179 (6%)
Frame = +1
Query: 88 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 252
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 253 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 429
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 430 ISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-----IDKRIYSMFESGAWDVTDLSSA 591
++ + +P D+Q C+ KFGS ++ ++D + +DKR F++G W++ + +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKR--DFFDNGEWEIVSATGS 226
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 71.7 bits (168), Expect = 2e-12
Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +1
Query: 220 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 393
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 394 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESGA 564
V W + +M + +P D Q C+ KFGS ++ +D + I++ + F++G
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 200
Query: 565 WDV 573
W++
Sbjct: 201 WEI 203
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 71.7 bits (168), Expect = 2e-12
Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +1
Query: 220 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 393
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 46 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 105
Query: 394 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESGA 564
V W + +M + +P D Q C+ KFGS ++ +D + I++ + F++G
Sbjct: 106 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 165
Query: 565 WDV 573
W++
Sbjct: 166 WEI 168
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 71.7 bits (168), Expect = 2e-12
Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +1
Query: 220 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 393
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 394 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESGA 564
V W + +M + +P D Q C+ KFGS ++ +D + I++ + F++G
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 200
Query: 565 WDV 573
W++
Sbjct: 201 WEI 203
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 71.7 bits (168), Expect = 2e-12
Identities = 43/179 (24%), Positives = 84/179 (46%), Gaps = 11/179 (6%)
Frame = +1
Query: 88 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 252
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 253 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 429
WN ++G V S+ W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSSWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 430 ISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-----IDKRIYSMFESGAWDVTDLSSA 591
++ + +P D+Q C+ KFGS ++ ++D + +DKR F++G W++ + +
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKR--DFFDNGEWEIVSATGS 226
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 71.7 bits (168), Expect = 2e-12
Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +1
Query: 220 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 393
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 394 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESGA 564
V W + +M + +P D Q C+ KFGS ++ +D + I++ + F++G
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 200
Query: 565 WDV 573
W++
Sbjct: 201 WEI 203
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 71.7 bits (168), Expect = 2e-12
Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +1
Query: 220 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 393
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 394 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESGA 564
V W + +M + +P D Q C+ KFGS ++ +D + I++ + F++G
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 200
Query: 565 WDV 573
W++
Sbjct: 201 WEI 203
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 71.7 bits (168), Expect = 2e-12
Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +1
Query: 220 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 393
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 394 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESGA 564
V W + +M + +P D Q C+ KFGS ++ +D + I++ + F++G
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 200
Query: 565 WDV 573
W++
Sbjct: 201 WEI 203
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 71.7 bits (168), Expect = 2e-12
Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Frame = +1
Query: 220 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 393
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 394 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESGA 564
V W + +M + +P D Q C+ KFGS ++ +D + I++ + F++G
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 200
Query: 565 WDV 573
W++
Sbjct: 201 WEI 203
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 71.3 bits (167), Expect = 3e-12
Identities = 49/194 (25%), Positives = 90/194 (46%), Gaps = 6/194 (3%)
Frame = +1
Query: 10 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-ANIR 186
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 17 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 73
Query: 187 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDY 360
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 74 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 133
Query: 361 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---D 531
+A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 134 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSS 193
Query: 532 KRIYSMFESGAWDV 573
+ +ESG W +
Sbjct: 194 MNLKDYWESGEWAI 207
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 71.3 bits (167), Expect = 3e-12
Identities = 49/194 (25%), Positives = 90/194 (46%), Gaps = 6/194 (3%)
Frame = +1
Query: 10 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-ANIR 186
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 18 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 74
Query: 187 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDY 360
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 75 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 134
Query: 361 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---D 531
+A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 135 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSS 194
Query: 532 KRIYSMFESGAWDV 573
+ +ESG W +
Sbjct: 195 MNLKDYWESGEWAI 208
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 71.3 bits (167), Expect = 3e-12
Identities = 49/194 (25%), Positives = 90/194 (46%), Gaps = 6/194 (3%)
Frame = +1
Query: 10 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-ANIR 186
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 17 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 73
Query: 187 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDY 360
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 74 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 133
Query: 361 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---D 531
+A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 134 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSS 193
Query: 532 KRIYSMFESGAWDV 573
+ +ESG W +
Sbjct: 194 MNLKDYWESGEWAI 207
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 71.3 bits (167), Expect = 3e-12
Identities = 49/194 (25%), Positives = 90/194 (46%), Gaps = 6/194 (3%)
Frame = +1
Query: 10 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-ANIR 186
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 19 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 75
Query: 187 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDY 360
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 76 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 135
Query: 361 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---D 531
+A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 136 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSS 195
Query: 532 KRIYSMFESGAWDV 573
+ +ESG W +
Sbjct: 196 MNLKDYWESGEWAI 209
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 71.3 bits (167), Expect = 3e-12
Identities = 49/194 (25%), Positives = 90/194 (46%), Gaps = 6/194 (3%)
Frame = +1
Query: 10 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-ANIR 186
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 19 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 75
Query: 187 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDY 360
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 76 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 135
Query: 361 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---D 531
+A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 136 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSS 195
Query: 532 KRIYSMFESGAWDV 573
+ +ESG W +
Sbjct: 196 MNLKDYWESGEWAI 209
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 71.3 bits (167), Expect = 3e-12
Identities = 49/194 (25%), Positives = 90/194 (46%), Gaps = 6/194 (3%)
Frame = +1
Query: 10 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-ANIR 186
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 18 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 74
Query: 187 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDY 360
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 75 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 134
Query: 361 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---D 531
+A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 135 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSS 194
Query: 532 KRIYSMFESGAWDV 573
+ +ESG W +
Sbjct: 195 MNLKDYWESGEWAI 208
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 71.3 bits (167), Expect = 3e-12
Identities = 49/194 (25%), Positives = 90/194 (46%), Gaps = 6/194 (3%)
Frame = +1
Query: 10 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-ANIR 186
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 19 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 75
Query: 187 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDY 360
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 76 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 135
Query: 361 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---D 531
+A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 136 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSS 195
Query: 532 KRIYSMFESGAWDV 573
+ +ESG W +
Sbjct: 196 MNLKDYWESGEWAI 209
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 71.3 bits (167), Expect = 3e-12
Identities = 49/194 (25%), Positives = 90/194 (46%), Gaps = 6/194 (3%)
Frame = +1
Query: 10 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-ANIR 186
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 19 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 75
Query: 187 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDY 360
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 76 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 135
Query: 361 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---D 531
+A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 136 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSS 195
Query: 532 KRIYSMFESGAWDV 573
+ +ESG W +
Sbjct: 196 MNLKDYWESGEWAI 209
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 71.3 bits (167), Expect = 3e-12
Identities = 49/194 (25%), Positives = 90/194 (46%), Gaps = 6/194 (3%)
Frame = +1
Query: 10 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-ANIR 186
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 19 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 75
Query: 187 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDY 360
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 76 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 135
Query: 361 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---D 531
+A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 136 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSS 195
Query: 532 KRIYSMFESGAWDV 573
+ +ESG W +
Sbjct: 196 MNLKDYWESGEWAI 209
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 71.3 bits (167), Expect = 3e-12
Identities = 49/194 (25%), Positives = 90/194 (46%), Gaps = 6/194 (3%)
Frame = +1
Query: 10 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-ANIR 186
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 19 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 75
Query: 187 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDY 360
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 76 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 135
Query: 361 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---D 531
+A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 136 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSS 195
Query: 532 KRIYSMFESGAWDV 573
+ +ESG W +
Sbjct: 196 MNLKDYWESGEWAI 209
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 71.3 bits (167), Expect = 3e-12
Identities = 49/194 (25%), Positives = 90/194 (46%), Gaps = 6/194 (3%)
Frame = +1
Query: 10 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-ANIR 186
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 18 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 74
Query: 187 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDY 360
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 75 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 134
Query: 361 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---D 531
+A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 135 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSS 194
Query: 532 KRIYSMFESGAWDV 573
+ +ESG W +
Sbjct: 195 MNLKDYWESGEWAI 208
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 71.3 bits (167), Expect = 3e-12
Identities = 49/194 (25%), Positives = 90/194 (46%), Gaps = 6/194 (3%)
Frame = +1
Query: 10 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-ANIR 186
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 13 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 69
Query: 187 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDY 360
E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D
Sbjct: 70 EVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD 129
Query: 361 ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---D 531
+A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 130 KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSS 189
Query: 532 KRIYSMFESGAWDV 573
+ +ESG W +
Sbjct: 190 MNLKDYWESGEWAI 203
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 70.5 bits (165), Expect = 5e-12
Identities = 36/123 (29%), Positives = 64/123 (52%), Gaps = 5/123 (4%)
Frame = +1
Query: 220 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 393
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 56 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 115
Query: 394 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI---DKRIYSMFESGA 564
V+WI + + + +P D Q CT KFGS ++ ++D V+ + +ESG
Sbjct: 116 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 175
Query: 565 WDV 573
W +
Sbjct: 176 WAI 178
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 70.1 bits (164), Expect = 7e-12
Identities = 41/135 (30%), Positives = 69/135 (51%), Gaps = 7/135 (5%)
Frame = +1
Query: 220 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 393
L+ W D +L WN ++G T L V SE +W PD+VL N A A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 394 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNS-----DEMDFVIDKRIYSMFES 558
V W+ + S+ + +P D Q C KFGS ++ ++M+ +D + Y +ES
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQMEQTVDLKDY--WES 228
Query: 559 GAWDVTDLSSAVQSQ 603
G W + + + S+
Sbjct: 229 GEWAIVNATGTYNSK 243
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 70.1 bits (164), Expect = 7e-12
Identities = 41/135 (30%), Positives = 69/135 (51%), Gaps = 7/135 (5%)
Frame = +1
Query: 220 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 393
L+ W D +L WN ++G T L V SE +W PD+VL N A A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 394 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNS-----DEMDFVIDKRIYSMFES 558
V W+ + S+ + +P D Q C KFGS ++ ++M+ +D + Y +ES
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQMEQTVDLKDY--WES 228
Query: 559 GAWDVTDLSSAVQSQ 603
G W + + + S+
Sbjct: 229 GEWAIVNATGTYNSK 243
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 69.7 bits (163), Expect = 9e-12
Identities = 47/188 (25%), Positives = 88/188 (46%), Gaps = 13/188 (6%)
Frame = +1
Query: 61 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 225
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 226 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 390
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 391 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD-FVIDKRI--YSMFESG 561
++W + M + +P D Q C+ KFGS ++ E+D +I ++ +E+
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENS 204
Query: 562 AWDVTDLS 585
W++ D S
Sbjct: 205 EWEIIDAS 212
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 69.7 bits (163), Expect = 9e-12
Identities = 47/188 (25%), Positives = 88/188 (46%), Gaps = 13/188 (6%)
Frame = +1
Query: 61 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 225
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 226 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 390
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 391 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD-FVIDKRI--YSMFESG 561
++W + M + +P D Q C+ KFGS ++ E+D +I ++ +E+
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENS 204
Query: 562 AWDVTDLS 585
W++ D S
Sbjct: 205 EWEIIDAS 212
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 69.7 bits (163), Expect = 9e-12
Identities = 47/188 (25%), Positives = 88/188 (46%), Gaps = 13/188 (6%)
Frame = +1
Query: 61 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 225
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 226 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 390
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 391 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD-FVIDKRI--YSMFESG 561
++W + M + +P D Q C+ KFGS ++ E+D +I ++ +E+
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENS 204
Query: 562 AWDVTDLS 585
W++ D S
Sbjct: 205 EWEIIDAS 212
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 69.7 bits (163), Expect = 9e-12
Identities = 47/188 (25%), Positives = 88/188 (46%), Gaps = 13/188 (6%)
Frame = +1
Query: 61 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 225
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 226 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 390
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 391 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD-FVIDKRI--YSMFESG 561
++W + M + +P D Q C+ KFGS ++ E+D +I ++ +E+
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENS 204
Query: 562 AWDVTDLS 585
W++ D S
Sbjct: 205 EWEIIDAS 212
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 69.3 bits (162), Expect = 1e-11
Identities = 55/202 (27%), Positives = 101/202 (50%), Gaps = 14/202 (6%)
Frame = +1
Query: 16 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANIR 186
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A +
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 187 ESESTVRILAD---LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 354
+ + +++ ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 355 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 522
D+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 523 V-IDKRI--YSMFESGAWDVTD 579
V + R+ +ESG W + D
Sbjct: 192 VNMHSRVDQLDFWESGEWVIVD 213
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 69.3 bits (162), Expect = 1e-11
Identities = 55/202 (27%), Positives = 101/202 (50%), Gaps = 14/202 (6%)
Frame = +1
Query: 16 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANIR 186
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A +
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 187 ESESTVRILAD---LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 354
+ + +++ ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 355 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 522
D+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 523 V-IDKRI--YSMFESGAWDVTD 579
V + R+ +ESG W + D
Sbjct: 192 VNMHSRVDQLDFWESGEWVIVD 213
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 69.3 bits (162), Expect = 1e-11
Identities = 55/202 (27%), Positives = 101/202 (50%), Gaps = 14/202 (6%)
Frame = +1
Query: 16 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANIR 186
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A +
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 187 ESESTVRILAD---LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 354
+ + +++ ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 355 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 522
D+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 523 V-IDKRI--YSMFESGAWDVTD 579
V + R+ +ESG W + D
Sbjct: 192 VNMHSRVDQLDFWESGEWVIVD 213
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 69.3 bits (162), Expect = 1e-11
Identities = 55/202 (27%), Positives = 101/202 (50%), Gaps = 14/202 (6%)
Frame = +1
Query: 16 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANIR 186
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A +
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 187 ESESTVRILAD---LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 354
+ + +++ ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 355 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 522
D+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 523 V-IDKRI--YSMFESGAWDVTD 579
V + R+ +ESG W + D
Sbjct: 192 VNMHSRVDQLDFWESGEWVIVD 213
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 69.3 bits (162), Expect = 1e-11
Identities = 55/202 (27%), Positives = 101/202 (50%), Gaps = 14/202 (6%)
Frame = +1
Query: 16 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANIR 186
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A +
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 187 ESESTVRILAD---LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 354
+ + +++ ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 355 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 522
D+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 523 V-IDKRI--YSMFESGAWDVTD 579
V + R+ +ESG W + D
Sbjct: 192 VNMHSRVDQLDFWESGEWVIVD 213
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 69.3 bits (162), Expect = 1e-11
Identities = 55/202 (27%), Positives = 101/202 (50%), Gaps = 14/202 (6%)
Frame = +1
Query: 16 LLPFLLTCAIASAAECEN-ATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANIR 186
LL L T + +++ E A + ++ L + Y++ S P + I VV + L A +
Sbjct: 15 LLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLI 74
Query: 187 ESESTVRILAD---LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 354
+ + +++ ++ W D +L W+ ++ T + + SE +WRPD+VL N A G
Sbjct: 75 DVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNAD---G 131
Query: 355 DYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 522
D+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 132 DFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL 191
Query: 523 V-IDKRI--YSMFESGAWDVTD 579
V + R+ +ESG W + D
Sbjct: 192 VNMHSRVDQLDFWESGEWVIVD 213
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 69.3 bits (162), Expect = 1e-11
Identities = 56/199 (28%), Positives = 90/199 (45%), Gaps = 9/199 (4%)
Frame = +1
Query: 13 ILLPF--LLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIV-VNLTLHLRHA-N 180
+LL F L C+ A+ E L+ S R + S++V V L + L +
Sbjct: 10 LLLGFGLLRLCSGVWGADTEERLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLIS 69
Query: 181 IRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAG 354
+ E E + L W D RL+W E+ + S+ +W PDVVL N A
Sbjct: 70 VHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYEV 129
Query: 355 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK 534
+ A VS +GS+ W+ + +++ ++P D Q CT KF S ++ E+D V+
Sbjct: 130 SFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLKS 189
Query: 535 RIYSMFE---SGAWDVTDL 582
+ S+ + SG WD+ L
Sbjct: 190 EVASLDDFTPSGEWDIVAL 208
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 68.9 bits (161), Expect = 2e-11
Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 6/153 (3%)
Frame = +1
Query: 142 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 315
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 316 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 492
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 493 RMHNSDEMDFVIDKRIYSMFE---SGAWDVTDL 582
++ E+D V+ + S+ + SG WD+ L
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 68.9 bits (161), Expect = 2e-11
Identities = 49/177 (27%), Positives = 90/177 (50%), Gaps = 13/177 (7%)
Frame = +1
Query: 88 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 252
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 15 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 74
Query: 253 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 417
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 75 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 131
Query: 418 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFESGAWDVTD 579
+ S+ + +P D Q CT KFGS ++ ++D V + R+ +ESG W + D
Sbjct: 132 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 188
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 68.9 bits (161), Expect = 2e-11
Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 6/153 (3%)
Frame = +1
Query: 142 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 315
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 316 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 492
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 493 RMHNSDEMDFVIDKRIYSMFE---SGAWDVTDL 582
++ E+D V+ + S+ + SG WD+ L
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 68.9 bits (161), Expect = 2e-11
Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 6/153 (3%)
Frame = +1
Query: 142 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 315
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 316 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 492
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 493 RMHNSDEMDFVIDKRIYSMFE---SGAWDVTDL 582
++ E+D V+ + S+ + SG WD+ L
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 68.9 bits (161), Expect = 2e-11
Identities = 50/197 (25%), Positives = 92/197 (46%), Gaps = 9/197 (4%)
Frame = +1
Query: 10 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-ANIR 186
++LL LL A AS AE L + ++ S P ++++ + + +
Sbjct: 16 LLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLVKVD 72
Query: 187 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 363
E + L+ W D +L WN +G + ++ V ++++W+PD+VL N A GD+
Sbjct: 73 EVNQIMETNLWLKQIWNDYKLKWNPSGYGGAEFMRVPAQKIWKPDIVLYNNAV---GDFQ 129
Query: 364 L----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVI- 528
+ +A + G V+WI + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 130 VTTKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLI 189
Query: 529 --DKRIYSMFESGAWDV 573
+ +ESG W +
Sbjct: 190 GSSMNLKDYWESGEWAI 206
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 68.9 bits (161), Expect = 2e-11
Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 6/153 (3%)
Frame = +1
Query: 142 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 315
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 316 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 492
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 493 RMHNSDEMDFVIDKRIYSMFE---SGAWDVTDL 582
++ E+D V+ + S+ + SG WD+ L
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 68.9 bits (161), Expect = 2e-11
Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 6/153 (3%)
Frame = +1
Query: 142 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 315
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 316 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 492
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 493 RMHNSDEMDFVIDKRIYSMFE---SGAWDVTDL 582
++ E+D V+ + S+ + SG WD+ L
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 68.9 bits (161), Expect = 2e-11
Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 6/153 (3%)
Frame = +1
Query: 142 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 315
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 316 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 492
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 493 RMHNSDEMDFVIDKRIYSMFE---SGAWDVTDL 582
++ E+D V+ + S+ + SG WD+ L
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 68.9 bits (161), Expect = 2e-11
Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 6/153 (3%)
Frame = +1
Query: 142 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 315
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 316 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 492
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 493 RMHNSDEMDFVIDKRIYSMFE---SGAWDVTDL 582
++ E+D V+ + S+ + SG WD+ L
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 64.9 bits (151), Expect = 3e-10
Identities = 47/137 (34%), Positives = 70/137 (51%), Gaps = 4/137 (2%)
Frame = +1
Query: 118 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 291
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 292 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDM 465
++E +W PDVVLLN D AL VS++GSV W + S+Q+ +P D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 466 QTCTFKFGSRMHNSDEM 516
Q CT F S ++S E+
Sbjct: 163 QNCTMVFSSYSYDSSEV 179
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 64.9 bits (151), Expect = 3e-10
Identities = 36/149 (24%), Positives = 71/149 (47%), Gaps = 9/149 (6%)
Frame = +1
Query: 220 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 396
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 20 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 79
Query: 397 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES------ 558
+ K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 80 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQ 139
Query: 559 --GAWDVTDLSSAVQSQDRGEVEARVAMF 639
G W++ LS A R + R +++
Sbjct: 140 THGEWELLGLSKATAKLSRVAIRRRPSLY 168
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 64.9 bits (151), Expect = 3e-10
Identities = 47/137 (34%), Positives = 70/137 (51%), Gaps = 4/137 (2%)
Frame = +1
Query: 118 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 291
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 292 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDM 465
++E +W PDVVLLN D AL VS++GSV W + S+Q+ +P D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 466 QTCTFKFGSRMHNSDEM 516
Q CT F S ++S E+
Sbjct: 163 QNCTMVFSSYSYDSSEV 179
>DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit E
splice variant HTR3Ea protein.
Length = 456
Score = 64.5 bits (150), Expect = 3e-10
Identities = 36/140 (25%), Positives = 67/140 (47%), Gaps = 9/140 (6%)
Frame = +1
Query: 220 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 396
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 91 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 150
Query: 397 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES------ 558
+ K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 151 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQ 210
Query: 559 --GAWDVTDLSSAVQSQDRG 612
G W++ LS A RG
Sbjct: 211 THGEWELLGLSKATAKLSRG 230
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 64.5 bits (150), Expect = 3e-10
Identities = 36/140 (25%), Positives = 67/140 (47%), Gaps = 9/140 (6%)
Frame = +1
Query: 220 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 396
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 397 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES------ 558
+ K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQ 225
Query: 559 --GAWDVTDLSSAVQSQDRG 612
G W++ LS A RG
Sbjct: 226 THGEWELLGLSKATAKLSRG 245
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 64.5 bits (150), Expect = 3e-10
Identities = 36/140 (25%), Positives = 67/140 (47%), Gaps = 9/140 (6%)
Frame = +1
Query: 220 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 396
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 397 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES------ 558
+ K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQ 225
Query: 559 --GAWDVTDLSSAVQSQDRG 612
G W++ LS A RG
Sbjct: 226 THGEWELLGLSKATAKLSRG 245
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 64.5 bits (150), Expect = 3e-10
Identities = 36/140 (25%), Positives = 67/140 (47%), Gaps = 9/140 (6%)
Frame = +1
Query: 220 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 396
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 397 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES------ 558
+ K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQ 225
Query: 559 --GAWDVTDLSSAVQSQDRG 612
G W++ LS A RG
Sbjct: 226 THGEWELLGLSKATAKLSRG 245
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 63.7 bits (148), Expect = 6e-10
Identities = 45/139 (32%), Positives = 71/139 (51%), Gaps = 6/139 (4%)
Frame = +1
Query: 118 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 291
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 292 SSERLWRPDVVLLNAAATTAGDY----ALRARVSNNGSVSWIKRLDISTPISMQLDNWPN 459
++E +W PDVVLLN G++ + VS++GSV W + S+Q+ +P
Sbjct: 104 TAESVWLPDVVLLN---NNDGNFYVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPF 160
Query: 460 DMQTCTFKFGSRMHNSDEM 516
D Q CT F S ++S E+
Sbjct: 161 DWQNCTMVFSSYSYDSSEV 179
>X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit CHRNE protein.
Length = 493
Score = 63.3 bits (147), Expect = 8e-10
Identities = 36/134 (26%), Positives = 71/134 (52%), Gaps = 3/134 (2%)
Frame = +1
Query: 130 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 303
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 304 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 480
+W P++VL N G Y V GSV+W+ + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 481 KFGSRMHNSDEMDF 522
F S+ +N++E++F
Sbjct: 165 IFRSQTYNAEEVEF 178
>AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit protein.
Length = 493
Score = 63.3 bits (147), Expect = 8e-10
Identities = 36/134 (26%), Positives = 71/134 (52%), Gaps = 3/134 (2%)
Frame = +1
Query: 130 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 303
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 304 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 480
+W P++VL N G Y V GSV+W+ + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 481 KFGSRMHNSDEMDF 522
F S+ +N++E++F
Sbjct: 165 IFRSQTYNAEEVEF 178
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 62.9 bits (146), Expect = 1e-09
Identities = 51/199 (25%), Positives = 91/199 (45%), Gaps = 13/199 (6%)
Frame = +1
Query: 22 PFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIR 186
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 187 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 363
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 364 L----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSD--EMDFV 525
+ + + G ++W + + + ++P D Q C+ K G+ ++ ++
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINPE 181
Query: 526 IDKRIYSMF-ESGAWDVTD 579
D+ S F ESG W + +
Sbjct: 182 SDQPDLSNFMESGEWVIKE 200
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 62.9 bits (146), Expect = 1e-09
Identities = 51/199 (25%), Positives = 91/199 (45%), Gaps = 13/199 (6%)
Frame = +1
Query: 22 PFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIR 186
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 187 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 363
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 364 L----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSD--EMDFV 525
+ + + G ++W + + + ++P D Q C+ K G+ ++ ++
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINPE 181
Query: 526 IDKRIYSMF-ESGAWDVTD 579
D+ S F ESG W + +
Sbjct: 182 SDQPDLSNFMESGEWVIKE 200
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 62.9 bits (146), Expect = 1e-09
Identities = 51/199 (25%), Positives = 91/199 (45%), Gaps = 13/199 (6%)
Frame = +1
Query: 22 PFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIR 186
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 187 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 363
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 364 L----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSD--EMDFV 525
+ + + G ++W + + + ++P D Q C+ K G+ ++ ++
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINPE 181
Query: 526 IDKRIYSMF-ESGAWDVTD 579
D+ S F ESG W + +
Sbjct: 182 SDQPDLSNFMESGEWVIKE 200
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 62.9 bits (146), Expect = 1e-09
Identities = 37/135 (27%), Positives = 67/135 (49%), Gaps = 1/135 (0%)
Frame = +1
Query: 220 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 396
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 397 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAWDVT 576
+ K + +++ ++ + +P D Q CTF F S ++ D M +DK + W++T
Sbjct: 151 KYDKPMRVTSICNLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEV--------WEIT 202
Query: 577 DLSSAVQSQDRGEVE 621
D S V Q +GE E
Sbjct: 203 DTSRKV-IQTQGEWE 216
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 62.9 bits (146), Expect = 1e-09
Identities = 51/199 (25%), Positives = 91/199 (45%), Gaps = 13/199 (6%)
Frame = +1
Query: 22 PFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIR 186
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 187 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 363
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 364 L----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSD--EMDFV 525
+ + + G ++W + + + ++P D Q C+ K G+ ++ ++
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINPE 181
Query: 526 IDKRIYSMF-ESGAWDVTD 579
D+ S F ESG W + +
Sbjct: 182 SDQPDLSNFMESGEWVIKE 200
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 62.9 bits (146), Expect = 1e-09
Identities = 51/199 (25%), Positives = 91/199 (45%), Gaps = 13/199 (6%)
Frame = +1
Query: 22 PFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIR 186
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 187 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYA 363
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 364 L----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSD--EMDFV 525
+ + + G ++W + + + ++P D Q C+ K G+ ++ ++
Sbjct: 122 IVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINPE 181
Query: 526 IDKRIYSMF-ESGAWDVTD 579
D+ S F ESG W + +
Sbjct: 182 SDQPDLSNFMESGEWVIKE 200
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 62.5 bits (145), Expect = 1e-09
Identities = 50/183 (27%), Positives = 84/183 (45%), Gaps = 8/183 (4%)
Frame = +1
Query: 10 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANI 183
++LL L C + N L+ D L+ YD P + VVN++L L N+
Sbjct: 8 LLLLLLLAVCLGGTQRNLRNQEE-RLLAD-LMQNYDPNLRPAERDSDVVNVSLKLTLTNL 65
Query: 184 ---RESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 351
E E + ++M W D RL W+ ++ G V S +WRPD+VL N
Sbjct: 66 ISLNEREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF 125
Query: 352 GDYALRARV--SNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 525
+ AL V S +G + W+ + S+ + +P D Q C+ F S+ ++++E+D
Sbjct: 126 -EVALYCNVLVSPDGCIYWLPPAIFRSACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQ 184
Query: 526 IDK 534
+ +
Sbjct: 185 LSQ 187
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 62.5 bits (145), Expect = 1e-09
Identities = 36/142 (25%), Positives = 67/142 (47%), Gaps = 9/142 (6%)
Frame = +1
Query: 214 ADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 390
A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 89 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 148
Query: 391 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES---- 558
+ + K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 149 RIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASRNI 208
Query: 559 ----GAWDVTDLSSAVQSQDRG 612
G W++ LS A RG
Sbjct: 209 LQTHGEWELLGLSKATAKLSRG 230
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 62.5 bits (145), Expect = 1e-09
Identities = 36/142 (25%), Positives = 67/142 (47%), Gaps = 9/142 (6%)
Frame = +1
Query: 214 ADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 390
A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 74 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 133
Query: 391 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFES---- 558
+ + K + + + ++ + +P D Q CT F S ++ D M ++K ++ + ++
Sbjct: 134 RIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASRNI 193
Query: 559 ----GAWDVTDLSSAVQSQDRG 612
G W++ LS A RG
Sbjct: 194 LQTHGEWELLGLSKATAKLSRG 215
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 62.5 bits (145), Expect = 1e-09
Identities = 37/135 (27%), Positives = 66/135 (48%), Gaps = 1/135 (0%)
Frame = +1
Query: 220 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 396
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 397 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAWDVT 576
+ K + +++ + + +P D Q CTF F S ++ D M +DK + W++T
Sbjct: 151 KYDKPMRVTSICKLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEV--------WEIT 202
Query: 577 DLSSAVQSQDRGEVE 621
D S V Q +GE E
Sbjct: 203 DTSRKV-IQTQGEWE 216
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 62.5 bits (145), Expect = 1e-09
Identities = 50/183 (27%), Positives = 84/183 (45%), Gaps = 8/183 (4%)
Frame = +1
Query: 10 IILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANI 183
++LL L C + N L+ D L+ YD P + VVN++L L N+
Sbjct: 8 LLLLLLLAVCLGGTQRNLRNQEE-RLLAD-LMQNYDPNLRPAERDSDVVNVSLKLTLTNL 65
Query: 184 ---RESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 351
E E + ++M W D RL W+ ++ G V S +WRPD+VL N
Sbjct: 66 ISLNEREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF 125
Query: 352 GDYALRARV--SNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 525
+ AL V S +G + W+ + S+ + +P D Q C+ F S+ ++++E+D
Sbjct: 126 -EVALYCNVLVSPDGCIYWLPPAIFRSACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQ 184
Query: 526 IDK 534
+ +
Sbjct: 185 LSQ 187
>BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 60.5 bits (140), Expect = 6e-09
Identities = 45/184 (24%), Positives = 84/184 (45%), Gaps = 10/184 (5%)
Frame = +1
Query: 52 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 219
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 220 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 390
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 391 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF--VIDKRIYSMF-ESG 561
++W + + + +P D Q C FGS +N +++D +D S F E
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDV 201
Query: 562 AWDV 573
W+V
Sbjct: 202 EWEV 205
>BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 60.5 bits (140), Expect = 6e-09
Identities = 45/184 (24%), Positives = 84/184 (45%), Gaps = 10/184 (5%)
Frame = +1
Query: 52 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 219
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 220 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 390
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 391 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF--VIDKRIYSMF-ESG 561
++W + + + +P D Q C FGS +N +++D +D S F E
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDV 201
Query: 562 AWDV 573
W+V
Sbjct: 202 EWEV 205
>AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 9 protein.
Length = 479
Score = 60.5 bits (140), Expect = 6e-09
Identities = 45/184 (24%), Positives = 84/184 (45%), Gaps = 10/184 (5%)
Frame = +1
Query: 52 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 219
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 220 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 390
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 391 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF--VIDKRIYSMF-ESG 561
++W + + + +P D Q C FGS +N +++D +D S F E
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDV 201
Query: 562 AWDV 573
W+V
Sbjct: 202 EWEV 205
>AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 479
Score = 60.5 bits (140), Expect = 6e-09
Identities = 45/184 (24%), Positives = 84/184 (45%), Gaps = 10/184 (5%)
Frame = +1
Query: 52 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 219
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 220 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 390
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 391 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF--VIDKRIYSMF-ESG 561
++W + + + +P D Q C FGS +N +++D +D S F E
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDV 201
Query: 562 AWDV 573
W+V
Sbjct: 202 EWEV 205
>AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 470
Score = 60.5 bits (140), Expect = 6e-09
Identities = 45/184 (24%), Positives = 84/184 (45%), Gaps = 10/184 (5%)
Frame = +1
Query: 52 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 219
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 16 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 75
Query: 220 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 390
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 76 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 135
Query: 391 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF--VIDKRIYSMF-ESG 561
++W + + + +P D Q C FGS +N +++D +D S F E
Sbjct: 136 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDV 195
Query: 562 AWDV 573
W+V
Sbjct: 196 EWEV 199
>AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 60.5 bits (140), Expect = 6e-09
Identities = 45/184 (24%), Positives = 84/184 (45%), Gaps = 10/184 (5%)
Frame = +1
Query: 52 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 219
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 220 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 390
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 391 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF--VIDKRIYSMF-ESG 561
++W + + + +P D Q C FGS +N +++D +D S F E
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDV 201
Query: 562 AWDV 573
W+V
Sbjct: 202 EWEV 205
>AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic
acetylcholine receptor subunit4 protein.
Length = 450
Score = 59.7 bits (138), Expect = 1e-08
Identities = 48/176 (27%), Positives = 77/176 (43%), Gaps = 7/176 (3%)
Frame = +1
Query: 13 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIR 186
+LL FLL A E +L L D L A Y P D+ +N+TL + + I
Sbjct: 12 LLLLFLLPAECLGA---EGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQII 67
Query: 187 ESESTVRILAD---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTA 351
+ + ++L ++ W D L W+ +G + S +WRPD+VL N A A
Sbjct: 68 DMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPP 127
Query: 352 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 519
G + + ++G+V W + + + +P D Q C FGS H ++D
Sbjct: 128 GSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic
acetylcholine alpha10 subunit protein.
Length = 450
Score = 59.7 bits (138), Expect = 1e-08
Identities = 48/176 (27%), Positives = 77/176 (43%), Gaps = 7/176 (3%)
Frame = +1
Query: 13 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIR 186
+LL FLL A E +L L D L A Y P D+ +N+TL + + I
Sbjct: 12 LLLLFLLPAECLGA---EGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQII 67
Query: 187 ESESTVRILAD---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTA 351
+ + ++L ++ W D L W+ +G + S +WRPD+VL N A A
Sbjct: 68 DMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPP 127
Query: 352 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 519
G + + ++G+V W + + + +P D Q C FGS H ++D
Sbjct: 128 GSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 59.7 bits (138), Expect = 1e-08
Identities = 48/176 (27%), Positives = 77/176 (43%), Gaps = 7/176 (3%)
Frame = +1
Query: 13 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIR 186
+LL FLL A E +L L D L A Y P D+ +N+TL + + I
Sbjct: 12 LLLLFLLPAECLGA---EGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQII 67
Query: 187 ESESTVRILAD---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTA 351
+ + ++L ++ W D L W+ +G + S +WRPD+VL N A A
Sbjct: 68 DMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPP 127
Query: 352 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 519
G + + ++G+V W + + + +P D Q C FGS H ++D
Sbjct: 128 GSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 59.7 bits (138), Expect = 1e-08
Identities = 48/176 (27%), Positives = 77/176 (43%), Gaps = 7/176 (3%)
Frame = +1
Query: 13 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIR 186
+LL FLL A E +L L D L A Y P D+ +N+TL + + I
Sbjct: 12 LLLLFLLPAECLGA---EGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQII 67
Query: 187 ESESTVRILAD---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTA 351
+ + ++L ++ W D L W+ +G + S +WRPD+VL N A A
Sbjct: 68 DMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPP 127
Query: 352 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 519
G + + ++G+V W + + + +P D Q C FGS H ++D
Sbjct: 128 GSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 56.4 bits (130), Expect = 9e-08
Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 3/124 (2%)
Frame = +1
Query: 220 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 393
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 55 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 114
Query: 394 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYSMFESGAWD 570
++ + + + +P D+Q C KFGS + +D + + I +G WD
Sbjct: 115 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 174
Query: 571 VTDL 582
+ +
Sbjct: 175 LVGI 178
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 56.4 bits (130), Expect = 9e-08
Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 3/124 (2%)
Frame = +1
Query: 220 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 393
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 394 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYSMFESGAWD 570
++ + + + +P D+Q C KFGS + +D + + I +G WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 571 VTDL 582
+ +
Sbjct: 198 LVGI 201
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 56.4 bits (130), Expect = 9e-08
Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 3/124 (2%)
Frame = +1
Query: 220 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 393
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 394 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYSMFESGAWD 570
++ + + + +P D+Q C KFGS + +D + + I +G WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 571 VTDL 582
+ +
Sbjct: 198 LVGI 201
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 56.4 bits (130), Expect = 9e-08
Identities = 38/142 (26%), Positives = 67/142 (47%), Gaps = 7/142 (4%)
Frame = +1
Query: 112 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 273
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 274 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 450
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 451 WPNDMQTCTFKFGSRMHNSDEM 516
+P D Q C+ KF S + + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 56.4 bits (130), Expect = 9e-08
Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 3/124 (2%)
Frame = +1
Query: 220 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 393
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 394 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYSMFESGAWD 570
++ + + + +P D+Q C KFGS + +D + + I +G WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 571 VTDL 582
+ +
Sbjct: 198 LVGI 201
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 56.4 bits (130), Expect = 9e-08
Identities = 38/142 (26%), Positives = 67/142 (47%), Gaps = 7/142 (4%)
Frame = +1
Query: 112 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 273
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 274 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 450
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 451 WPNDMQTCTFKFGSRMHNSDEM 516
+P D Q C+ KF S + + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 56.4 bits (130), Expect = 9e-08
Identities = 38/142 (26%), Positives = 67/142 (47%), Gaps = 7/142 (4%)
Frame = +1
Query: 112 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 273
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 274 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 450
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 451 WPNDMQTCTFKFGSRMHNSDEM 516
+P D Q C+ KF S + + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 56.4 bits (130), Expect = 9e-08
Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 3/124 (2%)
Frame = +1
Query: 220 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 393
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 394 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYSMFESGAWD 570
++ + + + +P D+Q C KFGS + +D + + I +G WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 571 VTDL 582
+ +
Sbjct: 198 LVGI 201
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 56.4 bits (130), Expect = 9e-08
Identities = 38/142 (26%), Positives = 67/142 (47%), Gaps = 7/142 (4%)
Frame = +1
Query: 112 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 273
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 274 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 450
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 451 WPNDMQTCTFKFGSRMHNSDEM 516
+P D Q C+ KF S + + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 55.2 bits (127), Expect = 2e-07
Identities = 32/124 (25%), Positives = 57/124 (45%), Gaps = 3/124 (2%)
Frame = +1
Query: 220 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 393
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 394 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYSMFESGAWD 570
++ + + + +P D+Q C KFGS + +D + + I +G WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 571 VTDL 582
+ +
Sbjct: 198 LVGI 201
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 55.2 bits (127), Expect = 2e-07
Identities = 32/124 (25%), Positives = 57/124 (45%), Gaps = 3/124 (2%)
Frame = +1
Query: 220 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 393
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 394 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYSMFESGAWD 570
++ + + + +P D+Q C KFGS + +D + + I +G WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 571 VTDL 582
+ +
Sbjct: 198 LVGI 201
>S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 474
Score = 54.8 bits (126), Expect = 3e-07
Identities = 44/182 (24%), Positives = 79/182 (43%), Gaps = 10/182 (5%)
Frame = +1
Query: 7 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 168
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 169 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 345
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 346 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 516
++ R+ +G+V + R+ + M L +P D Q CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 517 DF 522
+F
Sbjct: 189 EF 190
>S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 512
Score = 54.8 bits (126), Expect = 3e-07
Identities = 44/182 (24%), Positives = 79/182 (43%), Gaps = 10/182 (5%)
Frame = +1
Query: 7 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 168
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 169 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 345
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 346 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 516
++ R+ +G+V + R+ + M L +P D Q CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 517 DF 522
+F
Sbjct: 189 EF 190
>S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A
receptor beta 2 subunit protein.
Length = 474
Score = 54.8 bits (126), Expect = 3e-07
Identities = 44/182 (24%), Positives = 79/182 (43%), Gaps = 10/182 (5%)
Frame = +1
Query: 7 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 168
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 169 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 345
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 346 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 516
++ R+ +G+V + R+ + M L +P D Q CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 517 DF 522
+F
Sbjct: 189 EF 190
>BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 54.8 bits (126), Expect = 3e-07
Identities = 44/182 (24%), Positives = 79/182 (43%), Gaps = 10/182 (5%)
Frame = +1
Query: 7 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 168
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 169 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 345
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 346 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 516
++ R+ +G+V + R+ + M L +P D Q CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 517 DF 522
+F
Sbjct: 189 EF 190
>BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 54.8 bits (126), Expect = 3e-07
Identities = 44/182 (24%), Positives = 79/182 (43%), Gaps = 10/182 (5%)
Frame = +1
Query: 7 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 168
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 169 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 345
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 346 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 516
++ R+ +G+V + R+ + M L +P D Q CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 517 DF 522
+F
Sbjct: 189 EF 190
>BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 54.8 bits (126), Expect = 3e-07
Identities = 44/182 (24%), Positives = 79/182 (43%), Gaps = 10/182 (5%)
Frame = +1
Query: 7 YIILLPFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 168
Y + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 169 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 345
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 346 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 516
++ R+ +G+V + R+ + M L +P D Q CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 517 DF 522
+F
Sbjct: 189 EF 190
>M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid
receptor beta-1 subunit protein.
Length = 474
Score = 54.4 bits (125), Expect = 4e-07
Identities = 42/180 (23%), Positives = 79/180 (43%), Gaps = 9/180 (5%)
Frame = +1
Query: 10 IILLPFLLT--CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRH 174
++ P ++T C S E N + + +D LL YD PD + V + + +
Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71
Query: 175 AN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTA 351
+ + E + Q +W DKRLS++ + +++LW PD LN +
Sbjct: 72 IDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFV 131
Query: 352 GDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 522
++ R+ +G+V + R+ + M L +P D Q CT + S + +D+++F
Sbjct: 132 HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channel,
zinc activated 1 protein.
Length = 411
Score = 54.4 bits (125), Expect = 4e-07
Identities = 28/101 (27%), Positives = 49/101 (48%)
Frame = +1
Query: 220 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 399
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 400 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 522
L T + +L ++P D C+ F + + + E++F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channel
subunit protein.
Length = 411
Score = 54.4 bits (125), Expect = 4e-07
Identities = 28/101 (27%), Positives = 49/101 (48%)
Frame = +1
Query: 220 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 399
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 400 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 522
L T + +L ++P D C+ F + + + E++F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine receptor
alpha-5-subunit protein.
Length = 462
Score = 54.0 bits (124), Expect = 5e-07
Identities = 39/161 (24%), Positives = 73/161 (45%), Gaps = 7/161 (4%)
Frame = +1
Query: 64 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 231
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 232 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 402
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 403 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 525
RL IS MQL+++P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 54.0 bits (124), Expect = 5e-07
Identities = 39/161 (24%), Positives = 73/161 (45%), Gaps = 7/161 (4%)
Frame = +1
Query: 64 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 231
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 232 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 402
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 403 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 525
RL IS MQL+++P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 54.0 bits (124), Expect = 5e-07
Identities = 39/161 (24%), Positives = 73/161 (45%), Gaps = 7/161 (4%)
Frame = +1
Query: 64 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 231
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 232 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 402
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 403 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 525
RL IS MQL+++P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5, precursor protein.
Length = 462
Score = 54.0 bits (124), Expect = 5e-07
Identities = 39/161 (24%), Positives = 73/161 (45%), Gaps = 7/161 (4%)
Frame = +1
Query: 64 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 231
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 232 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 402
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 403 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFV 525
RL IS MQL+++P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channel
receptor L2 protein.
Length = 411
Score = 54.0 bits (124), Expect = 5e-07
Identities = 28/101 (27%), Positives = 49/101 (48%)
Frame = +1
Query: 220 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 399
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 400 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 522
L T + +L ++P D C+ F + + + E++F
Sbjct: 146 LNLALATETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1
subunit protein.
Length = 474
Score = 53.6 bits (123), Expect = 6e-07
Identities = 42/180 (23%), Positives = 78/180 (43%), Gaps = 9/180 (5%)
Frame = +1
Query: 10 IILLPFLLT--CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRH 174
++ P ++T C S E N + +D LL YD PD + V + + +
Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMPYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71
Query: 175 AN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTA 351
+ + E + Q +W DKRLS++ + +++LW PD LN +
Sbjct: 72 IDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFV 131
Query: 352 GDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 522
++ R+ +G+V + R+ + M L +P D Q CT + S + +D+++F
Sbjct: 132 HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein.
Length = 465
Score = 53.2 bits (122), Expect = 9e-07
Identities = 37/135 (27%), Positives = 60/135 (44%), Gaps = 7/135 (5%)
Frame = +1
Query: 22 PFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---R 186
P LL +A + ++ L+ YD P + VVN++L L N+
Sbjct: 7 PLLLLLLLAVCLGAQGRNQEERLLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLN 66
Query: 187 ESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAAT-TAGDY 360
E E + ++M W D RL W+ ++ G V S +WRPD+VL N + T + +
Sbjct: 67 EREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENKSQTYSTNEI 126
Query: 361 ALRARVSNNGSVSWI 405
L+ + S+ WI
Sbjct: 127 DLQLSQEDGQSIEWI 141
>S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type 3AS
receptor subunit protein.
Length = 478
Score = 52.4 bits (120), Expect = 1e-06
Identities = 39/175 (22%), Positives = 74/175 (42%), Gaps = 6/175 (3%)
Frame = +1
Query: 13 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHL---RHA 177
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYTKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 178 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 354
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINELVDVGKS 131
Query: 355 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 519
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor
protein.
Length = 238
Score = 52.4 bits (120), Expect = 1e-06
Identities = 40/171 (23%), Positives = 72/171 (42%), Gaps = 6/171 (3%)
Frame = +1
Query: 13 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHL---RHA 177
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 178 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 354
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 355 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNS 507
+ + G V K L + T S+ + N+P D+Q C+ F S +H S
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTS 182
>D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor
protein.
Length = 478
Score = 51.6 bits (118), Expect = 3e-06
Identities = 39/175 (22%), Positives = 74/175 (42%), Gaps = 6/175 (3%)
Frame = +1
Query: 13 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHL---RHA 177
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 178 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 354
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 355 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 519
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 484
Score = 51.6 bits (118), Expect = 3e-06
Identities = 39/175 (22%), Positives = 74/175 (42%), Gaps = 6/175 (3%)
Frame = +1
Query: 13 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHL---RHA 177
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 18 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 77
Query: 178 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 354
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 78 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 137
Query: 355 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 519
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 138 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 192
>BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 51.6 bits (118), Expect = 3e-06
Identities = 39/175 (22%), Positives = 74/175 (42%), Gaps = 6/175 (3%)
Frame = +1
Query: 13 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHL---RHA 177
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 178 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 354
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 355 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 519
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 51.6 bits (118), Expect = 3e-06
Identities = 39/175 (22%), Positives = 74/175 (42%), Gaps = 6/175 (3%)
Frame = +1
Query: 13 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHL---RHA 177
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 178 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 354
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 355 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 519
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor
protein.
Length = 478
Score = 51.6 bits (118), Expect = 3e-06
Identities = 39/175 (22%), Positives = 74/175 (42%), Gaps = 6/175 (3%)
Frame = +1
Query: 13 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHL---RHA 177
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 178 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 354
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 355 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 519
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3
receptor protein.
Length = 478
Score = 51.6 bits (118), Expect = 3e-06
Identities = 39/175 (22%), Positives = 74/175 (42%), Gaps = 6/175 (3%)
Frame = +1
Query: 13 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHL---RHA 177
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 178 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 354
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 355 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 519
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor
protein.
Length = 510
Score = 51.6 bits (118), Expect = 3e-06
Identities = 39/175 (22%), Positives = 74/175 (42%), Gaps = 6/175 (3%)
Frame = +1
Query: 13 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHL---RHA 177
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 178 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 354
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 355 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 519
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine
receptor 3A protein.
Length = 478
Score = 51.6 bits (118), Expect = 3e-06
Identities = 39/175 (22%), Positives = 74/175 (42%), Gaps = 6/175 (3%)
Frame = +1
Query: 13 ILLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHL---RHA 177
+LLP LL A + +L + D LL Y + P D + +++ +
Sbjct: 12 LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAIL 71
Query: 178 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 354
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 355 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 519
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 3 protein.
Length = 492
Score = 51.2 bits (117), Expect = 3e-06
Identities = 36/158 (22%), Positives = 70/158 (44%), Gaps = 7/158 (4%)
Frame = +1
Query: 64 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 231
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 232 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 402
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLPY 181
Query: 403 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 516
RL I M L+++P D+ C KFGS + + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa)
(LCP2). protein.
Length = 266
Score = 51.2 bits (117), Expect = 3e-06
Identities = 36/138 (26%), Positives = 56/138 (40%)
Frame = +1
Query: 220 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 399
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 87 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 146
Query: 400 WIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAWDVTD 579
L T + +L ++P D C+ F + + + R G W
Sbjct: 147 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTGADRAGAAGLR----RGGGRWGRGT 202
Query: 580 LSSAVQSQDRGEVEARVA 633
S VQ Q G+ E A
Sbjct: 203 PRSVVQGQGAGQGEGAKA 220
>S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 50.8 bits (116), Expect = 5e-06
Identities = 39/172 (22%), Positives = 73/172 (42%), Gaps = 7/172 (4%)
Frame = +1
Query: 73 TSLSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHAN-IRESESTVRILADLQMNWID 240
T ++L+++ LL YD++ PD I V+++ +++ + +I W D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 241 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 411
RL +N+ + +W PD + N+ A R+ N+G + + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 412 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 567
L I+ +QL N+P D +C F S + +EM + K + +W
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSW 216
>S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA
receptor alpha 3 subunit protein.
Length = 492
Score = 50.8 bits (116), Expect = 5e-06
Identities = 36/158 (22%), Positives = 70/158 (44%), Gaps = 7/158 (4%)
Frame = +1
Query: 64 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 231
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 232 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 402
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 403 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 516
RL I M L+++P D+ C KFGS + + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 50.8 bits (116), Expect = 5e-06
Identities = 39/172 (22%), Positives = 73/172 (42%), Gaps = 7/172 (4%)
Frame = +1
Query: 73 TSLSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHAN-IRESESTVRILADLQMNWID 240
T ++L+++ LL YD++ PD I V+++ +++ + +I W D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 241 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 411
RL +N+ + +W PD + N+ A R+ N+G + + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 412 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 567
L I+ +QL N+P D +C F S + +EM + K + +W
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSW 216
>AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 449
Score = 50.8 bits (116), Expect = 5e-06
Identities = 39/172 (22%), Positives = 73/172 (42%), Gaps = 7/172 (4%)
Frame = +1
Query: 73 TSLSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHAN-IRESESTVRILADLQMNWID 240
T ++L+++ LL YD++ PD I V+++ +++ + +I W D
Sbjct: 27 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 86
Query: 241 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 411
RL +N+ + +W PD + N+ A R+ N+G + + R
Sbjct: 87 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 146
Query: 412 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 567
L I+ +QL N+P D +C F S + +EM + K + +W
Sbjct: 147 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSW 198
>AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit
alpha 3 protein.
Length = 492
Score = 50.8 bits (116), Expect = 5e-06
Identities = 36/158 (22%), Positives = 70/158 (44%), Gaps = 7/158 (4%)
Frame = +1
Query: 64 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 231
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 232 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 402
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 403 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 516
RL I M L+++P D+ C KFGS + + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 50.0 bits (114), Expect = 8e-06
Identities = 39/145 (26%), Positives = 65/145 (44%), Gaps = 8/145 (5%)
Frame = +1
Query: 112 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 279
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 280 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 447
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 448 NWPNDMQTCTFKFGSRMHNSDEMDF 522
N+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 50.0 bits (114), Expect = 8e-06
Identities = 39/145 (26%), Positives = 65/145 (44%), Gaps = 8/145 (5%)
Frame = +1
Query: 112 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 279
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 280 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 447
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 448 NWPNDMQTCTFKFGSRMHNSDEMDF 522
N+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 50.0 bits (114), Expect = 8e-06
Identities = 39/145 (26%), Positives = 65/145 (44%), Gaps = 8/145 (5%)
Frame = +1
Query: 112 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 279
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 280 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 447
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 448 NWPNDMQTCTFKFGSRMHNSDEMDF 522
N+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 49.6 bits (113), Expect = 1e-05
Identities = 38/145 (26%), Positives = 65/145 (44%), Gaps = 8/145 (5%)
Frame = +1
Query: 112 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 279
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 280 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 447
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 448 NWPNDMQTCTFKFGSRMHNSDEMDF 522
N+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 49.6 bits (113), Expect = 1e-05
Identities = 38/145 (26%), Positives = 65/145 (44%), Gaps = 8/145 (5%)
Frame = +1
Query: 112 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 279
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 280 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 447
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 448 NWPNDMQTCTFKFGSRMHNSDEMDF 522
N+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 49.6 bits (113), Expect = 1e-05
Identities = 38/145 (26%), Positives = 65/145 (44%), Gaps = 8/145 (5%)
Frame = +1
Query: 112 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 279
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 280 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 447
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 448 NWPNDMQTCTFKFGSRMHNSDEMDF 522
N+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 49.6 bits (113), Expect = 1e-05
Identities = 38/145 (26%), Positives = 65/145 (44%), Gaps = 8/145 (5%)
Frame = +1
Query: 112 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 279
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 280 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 447
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 448 NWPNDMQTCTFKFGSRMHNSDEMDF 522
N+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 49.6 bits (113), Expect = 1e-05
Identities = 38/145 (26%), Positives = 65/145 (44%), Gaps = 8/145 (5%)
Frame = +1
Query: 112 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 279
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 280 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 447
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 448 NWPNDMQTCTFKFGSRMHNSDEMDF 522
N+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid type
A receptor alpha 6 subunit protein.
Length = 453
Score = 49.2 bits (112), Expect = 1e-05
Identities = 39/166 (23%), Positives = 71/166 (42%), Gaps = 8/166 (4%)
Frame = +1
Query: 76 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 243
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 244 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 414
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 415 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK-RIYSM 549
I+ M+L N+P D C KFGS + E+ + K +YS+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSV 196
>BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 49.2 bits (112), Expect = 1e-05
Identities = 39/166 (23%), Positives = 71/166 (42%), Gaps = 8/166 (4%)
Frame = +1
Query: 76 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 243
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 244 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 414
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 415 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK-RIYSM 549
I+ M+L N+P D C KFGS + E+ + K +YS+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSV 196
>BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 49.2 bits (112), Expect = 1e-05
Identities = 39/166 (23%), Positives = 71/166 (42%), Gaps = 8/166 (4%)
Frame = +1
Query: 76 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 243
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 244 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 414
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 415 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK-RIYSM 549
I+ M+L N+P D C KFGS + E+ + K +YS+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSV 196
>BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 49.2 bits (112), Expect = 1e-05
Identities = 39/166 (23%), Positives = 71/166 (42%), Gaps = 8/166 (4%)
Frame = +1
Query: 76 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 243
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 244 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 414
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 415 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK-RIYSM 549
I+ M+L N+P D C KFGS + E+ + K +YS+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSV 196
>BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 49.2 bits (112), Expect = 1e-05
Identities = 39/166 (23%), Positives = 71/166 (42%), Gaps = 8/166 (4%)
Frame = +1
Query: 76 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 243
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 244 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 414
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 415 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK-RIYSM 549
I+ M+L N+P D C KFGS + E+ + K +YS+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSV 196
>BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 1 protein.
Length = 474
Score = 49.2 bits (112), Expect = 1e-05
Identities = 41/180 (22%), Positives = 78/180 (43%), Gaps = 9/180 (5%)
Frame = +1
Query: 10 IILLPFLLT--CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRH 174
++ P ++T C S E N + + +D LL YD PD + V + + +
Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71
Query: 175 AN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTA 351
+ + E + Q +W DKRLS++ + +++L PD LN +
Sbjct: 72 IDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLCVPDTYFLNDKKSFV 131
Query: 352 GDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 522
++ R+ +G+V + R+ + M L +P D Q CT + S + +D+++F
Sbjct: 132 HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit
alpha4 protein.
Length = 554
Score = 48.4 bits (110), Expect = 2e-05
Identities = 32/119 (26%), Positives = 52/119 (43%), Gaps = 3/119 (2%)
Frame = +1
Query: 187 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL 366
E E T+ + + WIDKRL ++ + ++W PD N + + +
Sbjct: 90 EMEYTMDVF--FRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTA 147
Query: 367 RA---RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK 534
R+ NG++ + RL IS M+L ++P D C KFGS + EM + K
Sbjct: 148 PNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTK 206
>BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 4 protein.
Length = 554
Score = 48.4 bits (110), Expect = 2e-05
Identities = 32/119 (26%), Positives = 52/119 (43%), Gaps = 3/119 (2%)
Frame = +1
Query: 187 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL 366
E E T+ + + WIDKRL ++ + ++W PD N + + +
Sbjct: 90 EMEYTMDVF--FRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTA 147
Query: 367 RA---RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDK 534
R+ NG++ + RL IS M+L ++P D C KFGS + EM + K
Sbjct: 148 PNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTK 206
>U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 46.8 bits (106), Expect = 7e-05
Identities = 40/164 (24%), Positives = 78/164 (47%), Gaps = 9/164 (5%)
Frame = +1
Query: 58 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 222
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 223 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 390
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 391 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 522
+V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 46.8 bits (106), Expect = 7e-05
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +1
Query: 61 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 228
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 229 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 399
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 400 WIKRLDISTPISMQLDNWPNDMQTC 474
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 46.8 bits (106), Expect = 7e-05
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +1
Query: 61 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 228
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 229 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 399
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 400 WIKRLDISTPISMQLDNWPNDMQTC 474
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 46.8 bits (106), Expect = 7e-05
Identities = 40/164 (24%), Positives = 78/164 (47%), Gaps = 9/164 (5%)
Frame = +1
Query: 58 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 222
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 223 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 390
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 391 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 522
+V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 46.8 bits (106), Expect = 7e-05
Identities = 40/164 (24%), Positives = 78/164 (47%), Gaps = 9/164 (5%)
Frame = +1
Query: 58 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 222
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 223 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 390
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 391 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 522
+V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.8 bits (106), Expect = 7e-05
Identities = 33/123 (26%), Positives = 58/123 (47%), Gaps = 8/123 (6%)
Frame = +1
Query: 16 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 177
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 178 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 351
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N + T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTG 125
Query: 352 GDY 360
+
Sbjct: 126 STW 128
>BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.8 bits (106), Expect = 7e-05
Identities = 33/123 (26%), Positives = 58/123 (47%), Gaps = 8/123 (6%)
Frame = +1
Query: 16 LLPFLLTCAIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA-- 177
L+ F L A+ C A + ++D LL Y+ P S ++++ L L A
Sbjct: 7 LVLFFLV-ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQL 65
Query: 178 -NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTA 351
++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N + T
Sbjct: 66 ISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTG 125
Query: 352 GDY 360
+
Sbjct: 126 STW 128
>BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 46.8 bits (106), Expect = 7e-05
Identities = 40/164 (24%), Positives = 78/164 (47%), Gaps = 9/164 (5%)
Frame = +1
Query: 58 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 222
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 223 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 390
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 391 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 522
+V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 46.8 bits (106), Expect = 7e-05
Identities = 40/164 (24%), Positives = 78/164 (47%), Gaps = 9/164 (5%)
Frame = +1
Query: 58 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 222
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 223 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 390
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 391 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 522
+V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 46.8 bits (106), Expect = 7e-05
Identities = 38/149 (25%), Positives = 64/149 (42%), Gaps = 7/149 (4%)
Frame = +1
Query: 91 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 258
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 259 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 429
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 430 ISMQLDNWPNDMQTCTFKFGSRMHNSDEM 516
M L +P D Q C S ++S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 46.8 bits (106), Expect = 7e-05
Identities = 38/149 (25%), Positives = 64/149 (42%), Gaps = 7/149 (4%)
Frame = +1
Query: 91 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 258
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 259 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 429
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 430 ISMQLDNWPNDMQTCTFKFGSRMHNSDEM 516
M L +P D Q C S ++S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 46.8 bits (106), Expect = 7e-05
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +1
Query: 61 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 228
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 229 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 399
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 400 WIKRLDISTPISMQLDNWPNDMQTC 474
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 46.8 bits (106), Expect = 7e-05
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +1
Query: 61 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 228
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 48 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 107
Query: 229 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 399
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 108 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 167
Query: 400 WIKRLDISTPISMQLDNWPNDMQTC 474
+ RL + S+ L +P D Q C
Sbjct: 168 YGIRLTTTAACSLDLHKFPMDKQAC 192
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 46.8 bits (106), Expect = 7e-05
Identities = 38/149 (25%), Positives = 64/149 (42%), Gaps = 7/149 (4%)
Frame = +1
Query: 91 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 258
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 259 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 429
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 430 ISMQLDNWPNDMQTCTFKFGSRMHNSDEM 516
M L +P D Q C S ++S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 46.8 bits (106), Expect = 7e-05
Identities = 40/164 (24%), Positives = 78/164 (47%), Gaps = 9/164 (5%)
Frame = +1
Query: 58 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 222
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 223 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 390
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 391 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 522
+V + R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 46.0 bits (104), Expect = 1e-04
Identities = 45/181 (24%), Positives = 77/181 (42%), Gaps = 11/181 (6%)
Frame = +1
Query: 13 ILLPFLLTCAIASAAECENATSLSLMIDSLLAT---YDRESPPDSK-IVVNLTLHL---R 171
+LL + T SA S S +D L+ YD P+ K VN+T ++
Sbjct: 21 LLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINS 80
Query: 172 HANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATT 348
+I E+ R+ L+ W D RL+++ S + +W+PD+ N
Sbjct: 81 FGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGAN 140
Query: 349 AGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 519
+ R+ NG+V + RL ++ M L N+P D+QTC + S + +++
Sbjct: 141 FHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLI 200
Query: 520 F 522
F
Sbjct: 201 F 201
>BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 467
Score = 46.0 bits (104), Expect = 1e-04
Identities = 38/178 (21%), Positives = 77/178 (43%), Gaps = 9/178 (5%)
Frame = +1
Query: 79 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 240
+++++++LL YD + PD + +++ +++ N E T+ I W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIF--FAQTWYD 123
Query: 241 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKR 411
+RL +N+ ++W PD N+ A R+ N+G V + R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 412 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAWDVTDLS 585
L I +QL N+P D +C +F S + +E+ + + + ++ +W + S
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFS 241
>BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor, gamma 2, isoform 2 precursor protein.
Length = 467
Score = 46.0 bits (104), Expect = 1e-04
Identities = 38/178 (21%), Positives = 77/178 (43%), Gaps = 9/178 (5%)
Frame = +1
Query: 79 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 240
+++++++LL YD + PD + +++ +++ N E T+ I W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIF--FAQTWYD 123
Query: 241 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKR 411
+RL +N+ ++W PD N+ A R+ N+G V + R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 412 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAWDVTDLS 585
L I +QL N+P D +C +F S + +E+ + + + ++ +W + S
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFS 241
>BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 475
Score = 46.0 bits (104), Expect = 1e-04
Identities = 38/178 (21%), Positives = 77/178 (43%), Gaps = 9/178 (5%)
Frame = +1
Query: 79 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 240
+++++++LL YD + PD + +++ +++ N E T+ I W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIF--FAQTWYD 123
Query: 241 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKR 411
+RL +N+ ++W PD N+ A R+ N+G V + R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 412 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAWDVTDLS 585
L I +QL N+P D +C +F S + +E+ + + + ++ +W + S
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFS 241
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 46.0 bits (104), Expect = 1e-04
Identities = 45/181 (24%), Positives = 77/181 (42%), Gaps = 11/181 (6%)
Frame = +1
Query: 13 ILLPFLLTCAIASAAECENATSLSLMIDSLLAT---YDRESPPDSK-IVVNLTLHL---R 171
+LL + T SA S S +D L+ YD P+ K VN+T ++
Sbjct: 21 LLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINS 80
Query: 172 HANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATT 348
+I E+ R+ L+ W D RL+++ S + +W+PD+ N
Sbjct: 81 FGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGAN 140
Query: 349 AGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 519
+ R+ NG+V + RL ++ M L N+P D+QTC + S + +++
Sbjct: 141 FHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLI 200
Query: 520 F 522
F
Sbjct: 201 F 201
>AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor gamma 2 protein.
Length = 467
Score = 46.0 bits (104), Expect = 1e-04
Identities = 38/178 (21%), Positives = 77/178 (43%), Gaps = 9/178 (5%)
Frame = +1
Query: 79 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 240
+++++++LL YD + PD + +++ +++ N E T+ I W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIF--FAQTWYD 123
Query: 241 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKR 411
+RL +N+ ++W PD N+ A R+ N+G V + R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 412 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAWDVTDLS 585
L I +QL N+P D +C +F S + +E+ + + + ++ +W + S
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFS 241
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 46.0 bits (104), Expect = 1e-04
Identities = 45/181 (24%), Positives = 77/181 (42%), Gaps = 11/181 (6%)
Frame = +1
Query: 13 ILLPFLLTCAIASAAECENATSLSLMIDSLLAT---YDRESPPDSK-IVVNLTLHL---R 171
+LL + T SA S S +D L+ YD P+ K VN+T ++
Sbjct: 21 LLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINS 80
Query: 172 HANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATT 348
+I E+ R+ L+ W D RL+++ S + +W+PD+ N
Sbjct: 81 FGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGAN 140
Query: 349 AGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 519
+ R+ NG+V + RL ++ M L N+P D+QTC + S + +++
Sbjct: 141 FHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLI 200
Query: 520 F 522
F
Sbjct: 201 F 201
>X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2
subunit protein.
Length = 467
Score = 45.2 bits (102), Expect = 2e-04
Identities = 40/178 (22%), Positives = 79/178 (44%), Gaps = 9/178 (5%)
Frame = +1
Query: 79 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 240
+++++++LL YD + PD + +++ +++ N E T+ I QM W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFF-AQM-WYD 123
Query: 241 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKR 411
+RL +N+ ++W PD N+ A R+ N+G V + R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYSLR 183
Query: 412 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAWDVTDLS 585
L I +QL N+P D +C +F S + +E+ + + + ++ +W + S
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFS 241
>BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 1 protein.
Length = 465
Score = 45.2 bits (102), Expect = 2e-04
Identities = 39/172 (22%), Positives = 74/172 (43%), Gaps = 9/172 (5%)
Frame = +1
Query: 79 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHANIRES---ESTVRILADLQMNWID 240
++ +++SLL YD + PD + V+ +++ + E T+ I+ W D
Sbjct: 64 ITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDII--FAQTWFD 121
Query: 241 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 411
RL +N+ ++W PD N+ + A R+ N+G V + R
Sbjct: 122 SRLKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLR 181
Query: 412 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFESGAW 567
L I+ +QL N+P D +C +F S + +E+++ K + + W
Sbjct: 182 LTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYW 233
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 44.8 bits (101), Expect = 3e-04
Identities = 30/119 (25%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Frame = +1
Query: 178 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 354
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 355 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 522
+ R+S NG+V + R+ ++ M L N+P D+QTC + S + +++ F
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 196
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 44.8 bits (101), Expect = 3e-04
Identities = 30/119 (25%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Frame = +1
Query: 178 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 354
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 355 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 522
+ R+S NG+V + R+ ++ M L N+P D+QTC + S + +++ F
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 196
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia) protein.
Length = 449
Score = 44.8 bits (101), Expect = 3e-04
Identities = 30/119 (25%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Frame = +1
Query: 178 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 354
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 355 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 522
+ R+S NG+V + R+ ++ M L N+P D+QTC + S + +++ F
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 196
>AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 precursor variant
protein.
Length = 533
Score = 44.0 bits (99), Expect = 5e-04
Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 3/95 (3%)
Frame = +1
Query: 304 LWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 483
LW +A A + +A + ++G V W + S+ + +P D Q CT K
Sbjct: 25 LWLCCCTFTSADGDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMK 84
Query: 484 FGSRMHNSDEMDFV-IDKRI--YSMFESGAWDVTD 579
FGS ++ ++D V + R+ +ESG W + D
Sbjct: 85 FGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 119
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 43.6 bits (98), Expect = 7e-04
Identities = 37/145 (25%), Positives = 63/145 (43%), Gaps = 8/145 (5%)
Frame = +1
Query: 112 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 279
YD P+ K VN+T ++ ++I ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 280 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 447
S + +W+PD+ N + R+ NG+V + RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 448 NWPNDMQTCTFKFGSRMHNSDEMDF 522
N+P D+QTCT + S + ++ F
Sbjct: 137 NFPMDIQTCTMQLESFGYTMKDLVF 161
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 43.6 bits (98), Expect = 7e-04
Identities = 37/145 (25%), Positives = 63/145 (43%), Gaps = 8/145 (5%)
Frame = +1
Query: 112 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 279
YD P+ K VN+T ++ ++I ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 280 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 447
S + +W+PD+ N + R+ NG+V + RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 448 NWPNDMQTCTFKFGSRMHNSDEMDF 522
N+P D+QTCT + S + ++ F
Sbjct: 137 NFPMDIQTCTMQLESFGYTMKDLVF 161
>BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein.
Length = 556
Score = 43.2 bits (97), Expect = 0.001
Identities = 25/83 (30%), Positives = 43/83 (51%), Gaps = 7/83 (8%)
Frame = +1
Query: 352 GDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 519
GD+A+ +A + ++G V W + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 60 GDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 119
Query: 520 FV-IDKRI--YSMFESGAWDVTD 579
V + R+ +ESG W + D
Sbjct: 120 LVNMHSRVDQLDFWESGEWVIVD 142
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 42.3 bits (95), Expect = 0.002
Identities = 28/110 (25%), Positives = 50/110 (45%), Gaps = 4/110 (3%)
Frame = +1
Query: 205 RILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAGDYALR---A 372
R+ L+ W D RL++N S + +W+PD+ N +
Sbjct: 4 RVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLL 63
Query: 373 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDF 522
R+S NG+V + R+ ++ M L N+P D+QTC + S + +++ F
Sbjct: 64 RISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 113
>BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein.
Length = 1114
Score = 30.7 bits (66), Expect = 5.2
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +1
Query: 253 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 414
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled receptor
124 protein.
Length = 1331
Score = 30.7 bits (66), Expect = 5.2
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +1
Query: 253 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 414
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein.
Length = 1310
Score = 30.7 bits (66), Expect = 5.2
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +1
Query: 253 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 414
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 293 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 343
>AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marker 5
precursor protein.
Length = 1331
Score = 30.7 bits (66), Expect = 5.2
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +1
Query: 253 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 414
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein.
Length = 1206
Score = 30.7 bits (66), Expect = 5.2
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +1
Query: 253 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 414
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 406 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 456
>U90661-1|AAB50242.1| 1441|Homo sapiens steroid receptor
coactivator-1 protein.
Length = 1441
Score = 29.9 bits (64), Expect = 9.1
Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 1/53 (1%)
Frame = -2
Query: 358 SPRRWLQPRLAV-PRQASTSVPRTPAKCCSPIPLRSNSVVCRSNSFEDLPVSA 203
SPRR + LA PR + S P + SP+ + S++ + S+ ++PV++
Sbjct: 488 SPRRQVTSGLATRPRMPNNSFPPNISTLSSPVGMTSSACNNNNRSYSNIPVTS 540
>U59302-1|AAC50631.1| 1440|Homo sapiens steroid receptor
coactivator-1 F-SRC-1 protein.
Length = 1440
Score = 29.9 bits (64), Expect = 9.1
Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 1/53 (1%)
Frame = -2
Query: 358 SPRRWLQPRLAV-PRQASTSVPRTPAKCCSPIPLRSNSVVCRSNSFEDLPVSA 203
SPRR + LA PR + S P + SP+ + S++ + S+ ++PV++
Sbjct: 488 SPRRQVTSGLATRPRMPNNSFPPNISTLSSPVGMTSSACNNNNRSYSNIPVTS 540
>U40396-1|AAC50305.1| 1061|Homo sapiens steroid receptor coactivator
protein.
Length = 1061
Score = 29.9 bits (64), Expect = 9.1
Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 1/53 (1%)
Frame = -2
Query: 358 SPRRWLQPRLAV-PRQASTSVPRTPAKCCSPIPLRSNSVVCRSNSFEDLPVSA 203
SPRR + LA PR + S P + SP+ + S++ + S+ ++PV++
Sbjct: 108 SPRRQVTSGLATRPRMPNNSFPPNISTLSSPVGMTSSACNNNNRSYSNIPVTS 160
>EF660499-1|ABS29266.1| 1441|Homo sapiens nuclear receptor
coactivator 1 protein.
Length = 1441
Score = 29.9 bits (64), Expect = 9.1
Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 1/53 (1%)
Frame = -2
Query: 358 SPRRWLQPRLAV-PRQASTSVPRTPAKCCSPIPLRSNSVVCRSNSFEDLPVSA 203
SPRR + LA PR + S P + SP+ + S++ + S+ ++PV++
Sbjct: 488 SPRRQVTSGLATRPRMPNNSFPPNISTLSSPVGMTSSACNNNNRSYSNIPVTS 540
>BC111534-1|AAI11535.1| 1399|Homo sapiens nuclear receptor
coactivator 1 protein.
Length = 1399
Score = 29.9 bits (64), Expect = 9.1
Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 1/53 (1%)
Frame = -2
Query: 358 SPRRWLQPRLAV-PRQASTSVPRTPAKCCSPIPLRSNSVVCRSNSFEDLPVSA 203
SPRR + LA PR + S P + SP+ + S++ + S+ ++PV++
Sbjct: 488 SPRRQVTSGLATRPRMPNNSFPPNISTLSSPVGMTSSACNNNNRSYSNIPVTS 540
>BC111533-1|AAI11534.1| 1441|Homo sapiens nuclear receptor
coactivator 1 protein.
Length = 1441
Score = 29.9 bits (64), Expect = 9.1
Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 1/53 (1%)
Frame = -2
Query: 358 SPRRWLQPRLAV-PRQASTSVPRTPAKCCSPIPLRSNSVVCRSNSFEDLPVSA 203
SPRR + LA PR + S P + SP+ + S++ + S+ ++PV++
Sbjct: 488 SPRRQVTSGLATRPRMPNNSFPPNISTLSSPVGMTSSACNNNNRSYSNIPVTS 540
>BC039695-1|AAH39695.1| 1129|Homo sapiens JAK2 protein protein.
Length = 1129
Score = 29.9 bits (64), Expect = 9.1
Identities = 16/35 (45%), Positives = 20/35 (57%), Gaps = 2/35 (5%)
Frame = -2
Query: 283 KCCSPIPL-RSNSVVCRSNSFEDLPVSARWTR-TH 185
KCC P P +SN +V R+N D+P S R TH
Sbjct: 494 KCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTH 528
>AY973034-1|AAY22962.1| 1132|Homo sapiens Janus kinase 2 protein.
Length = 1132
Score = 29.9 bits (64), Expect = 9.1
Identities = 16/35 (45%), Positives = 20/35 (57%), Gaps = 2/35 (5%)
Frame = -2
Query: 283 KCCSPIPL-RSNSVVCRSNSFEDLPVSARWTR-TH 185
KCC P P +SN +V R+N D+P S R TH
Sbjct: 497 KCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTH 531
>AL161450-1|CAD13329.1| 1132|Homo sapiens Janus kinase 2 (a protein
tyrosine kinase) protein.
Length = 1132
Score = 29.9 bits (64), Expect = 9.1
Identities = 16/35 (45%), Positives = 20/35 (57%), Gaps = 2/35 (5%)
Frame = -2
Query: 283 KCCSPIPL-RSNSVVCRSNSFEDLPVSARWTR-TH 185
KCC P P +SN +V R+N D+P S R TH
Sbjct: 497 KCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTH 531
>AK093764-1|BAC04222.1| 360|Homo sapiens protein ( Homo sapiens
cDNA FLJ36445 fis, clone THYMU2013047. ).
Length = 360
Score = 29.9 bits (64), Expect = 9.1
Identities = 22/75 (29%), Positives = 36/75 (48%), Gaps = 4/75 (5%)
Frame = -3
Query: 375 TGAESVVPGGGCSRV*QYHVRPPQAF----RGHQPSAAAPFPCVPTQSFVDPIHLKICQY 208
+G ES P + Q + PP+ F RG++P+A P P+ S+ DP K C++
Sbjct: 37 SGEESTSPEQA-QTLGQDSLGPPEHFQGGPRGNEPAAHPPRWSTPS-SYEDPAGGKHCEH 94
Query: 207 PHGGLGLTNVSMSQM 163
P GL + + +
Sbjct: 95 PISGLEVLEAEQNSL 109
>AJ000882-1|CAA04372.1| 1399|Homo sapiens steroid receptor
coactivator 1e protein.
Length = 1399
Score = 29.9 bits (64), Expect = 9.1
Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 1/53 (1%)
Frame = -2
Query: 358 SPRRWLQPRLAV-PRQASTSVPRTPAKCCSPIPLRSNSVVCRSNSFEDLPVSA 203
SPRR + LA PR + S P + SP+ + S++ + S+ ++PV++
Sbjct: 488 SPRRQVTSGLATRPRMPNNSFPPNISTLSSPVGMTSSACNNNNRSYSNIPVTS 540
>AJ000881-1|CAA04371.1| 1441|Homo sapiens steroid receptor
coactivator protein.
Length = 1441
Score = 29.9 bits (64), Expect = 9.1
Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 1/53 (1%)
Frame = -2
Query: 358 SPRRWLQPRLAV-PRQASTSVPRTPAKCCSPIPLRSNSVVCRSNSFEDLPVSA 203
SPRR + LA PR + S P + SP+ + S++ + S+ ++PV++
Sbjct: 488 SPRRQVTSGLATRPRMPNNSFPPNISTLSSPVGMTSSACNNNNRSYSNIPVTS 540
>AF058925-1|AAC23982.1| 1132|Homo sapiens Jak2 kinase protein.
Length = 1132
Score = 29.9 bits (64), Expect = 9.1
Identities = 16/35 (45%), Positives = 20/35 (57%), Gaps = 2/35 (5%)
Frame = -2
Query: 283 KCCSPIPL-RSNSVVCRSNSFEDLPVSARWTR-TH 185
KCC P P +SN +V R+N D+P S R TH
Sbjct: 497 KCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTH 531
>AF005216-1|AAB82092.1| 1132|Homo sapiens receptor-associated
tyrosine kinase protein.
Length = 1132
Score = 29.9 bits (64), Expect = 9.1
Identities = 16/35 (45%), Positives = 20/35 (57%), Gaps = 2/35 (5%)
Frame = -2
Query: 283 KCCSPIPL-RSNSVVCRSNSFEDLPVSARWTR-TH 185
KCC P P +SN +V R+N D+P S R TH
Sbjct: 497 KCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTH 531
>AF001362-1|AAC23653.1| 1132|Homo sapiens Jak2 kinase protein.
Length = 1132
Score = 29.9 bits (64), Expect = 9.1
Identities = 16/35 (45%), Positives = 20/35 (57%), Gaps = 2/35 (5%)
Frame = -2
Query: 283 KCCSPIPL-RSNSVVCRSNSFEDLPVSARWTR-TH 185
KCC P P +SN +V R+N D+P S R TH
Sbjct: 497 KCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTH 531
>AC013459-1|AAX93184.1| 1441|Homo sapiens unknown protein.
Length = 1441
Score = 29.9 bits (64), Expect = 9.1
Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 1/53 (1%)
Frame = -2
Query: 358 SPRRWLQPRLAV-PRQASTSVPRTPAKCCSPIPLRSNSVVCRSNSFEDLPVSA 203
SPRR + LA PR + S P + SP+ + S++ + S+ ++PV++
Sbjct: 488 SPRRQVTSGLATRPRMPNNSFPPNISTLSSPVGMTSSACNNNNRSYSNIPVTS 540
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 112,874,494
Number of Sequences: 237096
Number of extensions: 2738675
Number of successful extensions: 8362
Number of sequences better than 10.0: 199
Number of HSP's better than 10.0 without gapping: 7607
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8205
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8007229802
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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