BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Nnor0116 (706 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_UPI0000D5551D Cluster: PREDICTED: similar to Pyruvate k... 260 3e-68 UniRef50_Q4SVB7 Cluster: Pyruvate kinase; n=1; Tetraodon nigrovi... 242 5e-63 UniRef50_P30613 Cluster: Pyruvate kinase isozymes R/L; n=167; Fu... 242 5e-63 UniRef50_Q9VD23 Cluster: Pyruvate kinase; n=5; Coelomata|Rep: Py... 198 8e-50 UniRef50_Q27686 Cluster: Pyruvate kinase; n=16; Kinetoplastida|R... 193 4e-48 UniRef50_Q9VQH0 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: P... 176 4e-43 UniRef50_Q7RVA8 Cluster: Pyruvate kinase; n=11; Ascomycota|Rep: ... 168 1e-40 UniRef50_Q42806 Cluster: Pyruvate kinase, cytosolic isozyme; n=6... 162 9e-39 UniRef50_Q9M057 Cluster: Pyruvate kinase; n=11; Magnoliophyta|Re... 157 3e-37 UniRef50_Q8EX62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr... 152 7e-36 UniRef50_A4E9R2 Cluster: Pyruvate kinase; n=1; Collinsella aerof... 150 3e-35 UniRef50_P77983 Cluster: Pyruvate kinase I; n=29; Bacteria|Rep: ... 147 3e-34 UniRef50_O44006 Cluster: Pyruvate kinase; n=10; cellular organis... 146 5e-34 UniRef50_P80885 Cluster: Pyruvate kinase; n=161; Bacteria|Rep: P... 145 8e-34 UniRef50_Q2TSW8 Cluster: Pyruvate kinase; n=4; stramenopiles|Rep... 145 1e-33 UniRef50_Q1FK29 Cluster: Pyruvate kinase; n=4; Clostridiales|Rep... 141 1e-32 UniRef50_Q2TSW6 Cluster: Pyruvate kinase; n=1; Achlya bisexualis... 140 4e-32 UniRef50_P52489 Cluster: Pyruvate kinase 2; n=33; Dikarya|Rep: P... 138 9e-32 UniRef50_Q22Z06 Cluster: Pyruvate kinase family protein; n=3; Ol... 138 1e-31 UniRef50_Q4U977 Cluster: Pyruvate kinase, putative; n=3; Piropla... 136 4e-31 UniRef50_Q9KUN0 Cluster: Pyruvate kinase; n=24; cellular organis... 135 9e-31 UniRef50_Q747D6 Cluster: Pyruvate kinase; n=6; Desulfuromonadale... 133 5e-30 UniRef50_Q55863 Cluster: Pyruvate kinase 1; n=5; Cyanobacteria|R... 131 2e-29 UniRef50_Q8TJ98 Cluster: Pyruvate kinase; n=2; Methanomicrobia|R... 130 2e-29 UniRef50_Q46078 Cluster: Pyruvate kinase; n=19; Actinobacteria (... 130 3e-29 UniRef50_A3I0G9 Cluster: Pyruvate kinase; n=3; Flexibacteraceae|... 129 6e-29 UniRef50_Q8PYY4 Cluster: Pyruvate kinase; n=3; Methanosarcinacea... 129 8e-29 UniRef50_Q090R5 Cluster: Pyruvate kinase; n=1; Stigmatella auran... 128 1e-28 UniRef50_Q81N35 Cluster: Pyruvate kinase; n=11; Bacillus cereus ... 127 2e-28 UniRef50_A7HIL5 Cluster: Pyruvate kinase; n=9; Bacteria|Rep: Pyr... 126 5e-28 UniRef50_Q6MLB5 Cluster: Pyruvate kinase; n=1; Bdellovibrio bact... 123 5e-27 UniRef50_Q1K4D5 Cluster: Pyruvate kinase; n=1; Desulfuromonas ac... 122 7e-27 UniRef50_Q08SK3 Cluster: Pyruvate kinase; n=2; Cystobacterineae|... 122 9e-27 UniRef50_Q2S3S2 Cluster: Pyruvate kinase; n=1; Salinibacter rube... 121 2e-26 UniRef50_Q2IHE2 Cluster: Pyruvate kinase; n=1; Anaeromyxobacter ... 120 3e-26 UniRef50_Q3JCE7 Cluster: Pyruvate kinase; n=1; Nitrosococcus oce... 120 5e-26 UniRef50_Q6A9P1 Cluster: Pyruvate kinase; n=4; Actinomycetales|R... 118 1e-25 UniRef50_O06134 Cluster: Pyruvate kinase; n=29; Bacteria|Rep: Py... 118 1e-25 UniRef50_Q5V4I8 Cluster: Pyruvate kinase; n=4; Halobacteriaceae|... 118 1e-25 UniRef50_A7CUA8 Cluster: Pyruvate kinase; n=1; Opitutaceae bacte... 118 2e-25 UniRef50_Q0W8N0 Cluster: Pyruvate kinase; n=7; cellular organism... 117 2e-25 UniRef50_A5C814 Cluster: Pyruvate kinase; n=1; Vitis vinifera|Re... 116 6e-25 UniRef50_Q1IJ65 Cluster: Pyruvate kinase; n=6; Bacteria|Rep: Pyr... 115 1e-24 UniRef50_Q1IHI1 Cluster: Pyruvate kinase; n=2; Bacteria|Rep: Pyr... 115 1e-24 UniRef50_Q56301 Cluster: Pyruvate kinase; n=5; Thermococcaceae|R... 115 1e-24 UniRef50_Q2I6K6 Cluster: Pyruvate kinase; n=1; uncultured delta ... 114 2e-24 UniRef50_Q1NTW3 Cluster: Pyruvate kinase; n=1; delta proteobacte... 114 2e-24 UniRef50_A1BQT0 Cluster: Pyruvate kinase; n=2; Eukaryota|Rep: Py... 114 2e-24 UniRef50_UPI0000DB6F59 Cluster: PREDICTED: similar to Pyruvate k... 113 3e-24 UniRef50_Q8F253 Cluster: Pyruvate kinase; n=4; Leptospira|Rep: P... 113 4e-24 UniRef50_Q40546 Cluster: Pyruvate kinase isozyme G, chloroplast ... 113 4e-24 UniRef50_UPI00015BD1E0 Cluster: UPI00015BD1E0 related cluster; n... 113 5e-24 UniRef50_A4MK73 Cluster: Pyruvate kinase; n=1; Petrotoga mobilis... 112 7e-24 UniRef50_Q9RR62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr... 112 9e-24 UniRef50_Q6MAN9 Cluster: Pyruvate kinase; n=1; Candidatus Protoc... 111 1e-23 UniRef50_Q56XD5 Cluster: Pyruvate kinase; n=14; Magnoliophyta|Re... 111 2e-23 UniRef50_Q1AXJ8 Cluster: Pyruvate kinase; n=1; Rubrobacter xylan... 111 2e-23 UniRef50_UPI0000D56D72 Cluster: PREDICTED: similar to CG7070-PB,... 110 3e-23 UniRef50_Q8YTZ8 Cluster: Pyruvate kinase; n=3; Nostocaceae|Rep: ... 109 5e-23 UniRef50_Q44473 Cluster: Pyruvate kinase; n=4; Proteobacteria|Re... 109 5e-23 UniRef50_Q1Q4I4 Cluster: Strongly similar to pyruvate kinase; n=... 109 9e-23 UniRef50_A7D456 Cluster: Pyruvate kinase; n=2; Halobacteriaceae|... 108 2e-22 UniRef50_A6LH43 Cluster: Pyruvate kinase; n=2; Parabacteroides|R... 107 3e-22 UniRef50_A0QNT2 Cluster: Pyruvate kinase; n=1; Mycobacterium sme... 107 3e-22 UniRef50_P94685 Cluster: Pyruvate kinase; n=8; Chlamydiaceae|Rep... 106 6e-22 UniRef50_Q82XE9 Cluster: Pyruvate kinase family; n=130; Proteoba... 105 1e-21 UniRef50_Q2JLA2 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep... 105 1e-21 UniRef50_A6Q7D7 Cluster: Pyruvate kinase; n=19; cellular organis... 105 1e-21 UniRef50_P73534 Cluster: Pyruvate kinase 2; n=37; Bacteria|Rep: ... 105 1e-21 UniRef50_A4APL1 Cluster: Pyruvate kinase; n=15; Bacteroidetes|Re... 104 2e-21 UniRef50_Q8G5M1 Cluster: Pyruvate kinase; n=23; Actinobacteridae... 103 3e-21 UniRef50_Q8SQP0 Cluster: Pyruvate kinase; n=1; Encephalitozoon c... 103 3e-21 UniRef50_A6FYT4 Cluster: Pyruvate kinase; n=1; Plesiocystis paci... 103 4e-21 UniRef50_Q7UF82 Cluster: Pyruvate kinase; n=1; Pirellula sp.|Rep... 102 1e-20 UniRef50_A0L7K0 Cluster: Pyruvate kinase; n=1; Magnetococcus sp.... 101 1e-20 UniRef50_A7CAK5 Cluster: Pyruvate kinase; n=3; Ralstonia pickett... 100 3e-20 UniRef50_Q6YQT6 Cluster: Pyruvate kinase; n=6; Candidatus Phytop... 100 4e-20 UniRef50_A6DH47 Cluster: Pyruvate kinase; n=1; Lentisphaera aran... 100 4e-20 UniRef50_Q6AII5 Cluster: Pyruvate kinase; n=1; Desulfotalea psyc... 100 7e-20 UniRef50_O05118 Cluster: Pyruvate kinase; n=44; Proteobacteria|R... 98 2e-19 UniRef50_Q04668 Cluster: Pyruvate kinase; n=2; Leishmania brazil... 97 3e-19 UniRef50_A6C474 Cluster: Pyruvate kinase; n=1; Planctomyces mari... 96 6e-19 UniRef50_A6Q5W9 Cluster: Pyruvate kinase; n=2; Epsilonproteobact... 96 9e-19 UniRef50_A1WED1 Cluster: Pyruvate kinase; n=1; Verminephrobacter... 96 9e-19 UniRef50_Q6KHW9 Cluster: Pyruvate kinase; n=3; Mycoplasma|Rep: P... 95 1e-18 UniRef50_A0L5K6 Cluster: Pyruvate kinase; n=5; Proteobacteria|Re... 95 1e-18 UniRef50_Q64MR8 Cluster: Pyruvate kinase; n=6; Bacteroides|Rep: ... 95 2e-18 UniRef50_Q63P20 Cluster: Pyruvate kinase; n=74; Proteobacteria|R... 93 6e-18 UniRef50_Q2TSX0 Cluster: Pyruvate kinase; n=2; cellular organism... 92 1e-17 UniRef50_Q9WY51 Cluster: Pyruvate kinase; n=3; Thermotogaceae|Re... 92 1e-17 UniRef50_Q9YEU2 Cluster: Pyruvate kinase; n=1; Aeropyrum pernix|... 91 2e-17 UniRef50_O51323 Cluster: Pyruvate kinase; n=5; cellular organism... 89 7e-17 UniRef50_Q7QVW2 Cluster: Pyruvate kinase; n=1; Giardia lamblia A... 89 1e-16 UniRef50_UPI0000DA20CA Cluster: PREDICTED: similar to Pyruvate k... 89 1e-16 UniRef50_Q5C2V0 Cluster: Pyruvate kinase; n=1; Schistosoma japon... 89 1e-16 UniRef50_Q8ZNW0 Cluster: Pyruvate kinase II; n=173; Proteobacter... 88 2e-16 UniRef50_A1IEN3 Cluster: Pyruvate kinase; n=1; Candidatus Desulf... 86 7e-16 UniRef50_Q9VFG4 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: P... 85 2e-15 UniRef50_Q6F1U1 Cluster: Pyruvate kinase; n=10; Mollicutes|Rep: ... 84 3e-15 UniRef50_Q40545 Cluster: Pyruvate kinase isozyme A, chloroplast ... 84 3e-15 UniRef50_Q0C0E8 Cluster: Pyruvate kinase; n=1; Hyphomonas neptun... 84 4e-15 UniRef50_Q1MPC8 Cluster: Pyruvate kinase; n=4; Desulfovibrionace... 83 6e-15 UniRef50_Q1ZJ78 Cluster: Pyruvate kinase; n=1; Psychromonas sp. ... 83 9e-15 UniRef50_A3ZTM3 Cluster: Pyruvate kinase; n=1; Blastopirellula m... 83 9e-15 UniRef50_Q5IX04 Cluster: Pyruvate kinase; n=1; Prototheca wicker... 83 9e-15 UniRef50_Q5ZZ75 Cluster: Pyruvate kinase II; n=4; Legionella pne... 82 1e-14 UniRef50_Q0PQH4 Cluster: Pyruvate kinase; n=1; Endoriftia persep... 82 1e-14 UniRef50_Q94KE3 Cluster: Pyruvate kinase; n=25; Magnoliophyta|Re... 82 1e-14 UniRef50_Q4YDL9 Cluster: Putative uncharacterized protein; n=1; ... 81 2e-14 UniRef50_A7APT5 Cluster: Pyruvate kinase family protein; n=1; Ba... 81 2e-14 UniRef50_Q07637 Cluster: Pyruvate kinase; n=44; Streptococcaceae... 81 2e-14 UniRef50_Q9PF54 Cluster: Pyruvate kinase; n=11; Xanthomonadaceae... 81 3e-14 UniRef50_A7PC98 Cluster: Chromosome chr2 scaffold_11, whole geno... 81 3e-14 UniRef50_Q2FMN4 Cluster: Pyruvate kinase; n=1; Methanospirillum ... 80 5e-14 UniRef50_Q7P1G4 Cluster: Pyruvate kinase; n=4; Bacteria|Rep: Pyr... 80 6e-14 UniRef50_P78031 Cluster: Pyruvate kinase; n=6; Mycoplasma|Rep: P... 80 6e-14 UniRef50_Q0AHE3 Cluster: Pyruvate kinase; n=2; Nitrosomonadaceae... 78 2e-13 UniRef50_Q8IJ37 Cluster: Pyruvate kinase; n=7; Plasmodium|Rep: P... 78 2e-13 UniRef50_A3DMY9 Cluster: Pyruvate kinase; n=1; Staphylothermus m... 74 3e-12 UniRef50_Q8EWX2 Cluster: Pyruvate kinase; n=1; Mycoplasma penetr... 74 4e-12 UniRef50_Q6L281 Cluster: Pyruvate kinase; n=2; Thermoplasmatales... 73 5e-12 UniRef50_P32044 Cluster: Pyruvate kinase; n=2; Thermoplasma|Rep:... 73 5e-12 UniRef50_Q4N603 Cluster: Pyruvate kinase; n=2; Theileria|Rep: Py... 72 2e-11 UniRef50_A7QH42 Cluster: Chromosome chr3 scaffold_95, whole geno... 70 6e-11 UniRef50_A2BLH1 Cluster: Pyruvate kinase; n=1; Hyperthermus buty... 66 8e-10 UniRef50_Q97ZD7 Cluster: Pyruvate kinase; n=4; Sulfolobaceae|Rep... 64 3e-09 UniRef50_P19680 Cluster: Pyruvate kinase; n=1; Spiroplasma citri... 64 3e-09 UniRef50_UPI00006CE5D4 Cluster: pyruvate kinase family protein; ... 64 4e-09 UniRef50_A7QTW5 Cluster: Chromosome undetermined scaffold_171, w... 62 1e-08 UniRef50_A3ALA5 Cluster: Pyruvate kinase; n=3; Oryza sativa|Rep:... 62 1e-08 UniRef50_A5JEK8 Cluster: Pyruvate kinase; n=1; Nosema bombycis|R... 62 2e-08 UniRef50_Q8MR79 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: P... 59 1e-07 UniRef50_Q7NJ33 Cluster: Pyruvate kinase; n=1; Gloeobacter viola... 58 2e-07 UniRef50_UPI0000E481DE Cluster: PREDICTED: hypothetical protein;... 57 5e-07 UniRef50_Q3J5D7 Cluster: Pyruvate kinase; n=2; Rhodobacter sphae... 54 5e-06 UniRef50_P46614 Cluster: Pyruvate kinase; n=1; Candida albicans|... 54 5e-06 UniRef50_A1RX09 Cluster: Pyruvate kinase; n=1; Thermofilum pende... 53 8e-06 UniRef50_Q9PQV7 Cluster: Pyruvate kinase; n=1; Ureaplasma parvum... 52 1e-05 UniRef50_Q2JJ60 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr... 50 7e-05 UniRef50_A6LTB0 Cluster: Pyruvate kinase; n=1; Clostridium beije... 49 1e-04 UniRef50_UPI000155B976 Cluster: PREDICTED: similar to pyruvate k... 48 3e-04 UniRef50_A0NLM6 Cluster: Pyruvate kinase; n=2; Alphaproteobacter... 47 5e-04 UniRef50_Q22CT0 Cluster: Pyruvate kinase, barrel domain containi... 47 5e-04 UniRef50_A3PTF7 Cluster: Pyruvate kinase; n=5; Mycobacterium|Rep... 45 0.002 UniRef50_A4ARB8 Cluster: Pyruvate kinase; n=1; Flavobacteriales ... 44 0.005 UniRef50_A7QZ91 Cluster: Chromosome undetermined scaffold_267, w... 43 0.008 UniRef50_Q5KVI2 Cluster: Pyruvate kinase; n=2; Geobacillus|Rep: ... 42 0.015 UniRef50_A6PU80 Cluster: Pyruvate kinase; n=1; Victivallis vaden... 42 0.015 UniRef50_A1U5Q4 Cluster: Pyruvate kinase; n=2; Marinobacter aqua... 42 0.020 UniRef50_Q59ZE3 Cluster: Putative uncharacterized protein; n=1; ... 42 0.020 UniRef50_Q57572 Cluster: Pyruvate kinase; n=6; Methanococcales|R... 42 0.020 UniRef50_Q4IUP8 Cluster: Pyruvate kinase; n=1; Azotobacter vinel... 41 0.034 UniRef50_A6PUS2 Cluster: Pyruvate kinase; n=1; Victivallis vaden... 40 0.045 UniRef50_Q9V2V8 Cluster: Pyruvate kinase; n=1; Thermoproteus ten... 40 0.045 UniRef50_A4VPY3 Cluster: Pyruvate kinase; n=1; Pseudomonas stutz... 40 0.060 UniRef50_Q8DLH6 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep... 40 0.079 UniRef50_Q9VVH0 Cluster: CG12229-PA; n=2; Sophophora|Rep: CG1222... 40 0.079 UniRef50_Q5M6U9 Cluster: Pyruvate kinase; n=2; Campylobacter jej... 39 0.14 UniRef50_Q9M3B6 Cluster: Pyruvate kinase; n=1; Arabidopsis thali... 37 0.42 UniRef50_UPI00006CB055 Cluster: hypothetical protein TTHERM_0023... 37 0.55 UniRef50_Q8XLL6 Cluster: Pyruvate kinase; n=3; Clostridium perfr... 36 0.97 UniRef50_A0V3R8 Cluster: S-layer-like region; n=1; Clostridium c... 36 1.3 UniRef50_UPI0000DB7164 Cluster: PREDICTED: similar to CG31559-PA... 35 1.7 UniRef50_Q8FLV7 Cluster: Pyruvate kinase; n=6; Corynebacterium|R... 35 1.7 UniRef50_A2STG1 Cluster: Putative anti-sigma regulatory factor, ... 35 1.7 UniRef50_A3CQV6 Cluster: Conserved uncharacterized protein; n=9;... 35 2.2 UniRef50_Q89VQ2 Cluster: ABC transporter peptide-binding protein... 34 3.0 UniRef50_A5NL17 Cluster: ATP-dependent Clp protease, ATP-binding... 34 3.0 UniRef50_Q4CYW8 Cluster: Putative uncharacterized protein; n=3; ... 34 3.0 UniRef50_A3CLR6 Cluster: Fibril-like structure subunit FibA, put... 33 5.2 UniRef50_Q58MH8 Cluster: Putative uncharacterized protein; n=1; ... 33 5.2 UniRef50_Q8EYH8 Cluster: MutS-like mismatch repair protein, ATPa... 33 6.8 UniRef50_Q2AHN9 Cluster: Radical SAM; n=1; Halothermothrix oreni... 33 6.8 UniRef50_Q3EBL2 Cluster: Uncharacterized protein At2g37440.1; n=... 33 6.8 UniRef50_Q46513 Cluster: ORF 2 gene product; n=1; Desulfurococcu... 33 9.0 >UniRef50_UPI0000D5551D Cluster: PREDICTED: similar to Pyruvate kinase (PK); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Pyruvate kinase (PK) - Tribolium castaneum Length = 557 Score = 260 bits (636), Expect = 3e-68 Identities = 121/199 (60%), Positives = 151/199 (75%) Frame = +1 Query: 109 SQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYH 288 +QL H LDI S +RL+GIICT+GP++ +V LE+M+E GMN+AR+ SHG+ E H Sbjct: 32 TQLDHNSLLDIQSHPPQVRLTGIICTLGPSTTDVETLERMIEAGMNIARLTLSHGTQEMH 91 Query: 289 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 468 E I+N R A ++YS +LG + L++ALD KGPE+RTG +EGG +AEVELKKGE IKLTT Sbjct: 92 TELIQNVRTAVENYSKRLGVMYPLSLALDIKGPEVRTGYMEGGIAAEVELKKGEQIKLTT 151 Query: 469 SPDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLG 648 Y EKG++ IYVDY NI VV+PGNRIF+DDGLIS+IC SV LTC++ENGGMLG Sbjct: 152 DKAYLEKGSSSVIYVDYDNIQKVVQPGNRIFLDDGLISLICTSVQGSVLTCSVENGGMLG 211 Query: 649 SRKGVNLPGIPVDLPAVSE 705 S K VNLPGI +DLP VSE Sbjct: 212 SCKNVNLPGIDIDLPVVSE 230 >UniRef50_Q4SVB7 Cluster: Pyruvate kinase; n=1; Tetraodon nigroviridis|Rep: Pyruvate kinase - Tetraodon nigroviridis (Green puffer) Length = 569 Score = 242 bits (593), Expect = 5e-63 Identities = 119/204 (58%), Positives = 153/204 (75%), Gaps = 7/204 (3%) Frame = +1 Query: 115 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 294 L+HMC LDIDS + R +GIICTIGPASR+V +L++M+++GMN+AR+NFSHG+HEYHAE Sbjct: 25 LEHMCLLDIDSAPTTARNTGIICTIGPASRSVGMLKEMIKSGMNIARLNFSHGTHEYHAE 84 Query: 295 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSP 474 TI+N REA +S+ + IALDTKGPEIRTGL+ G G+AEVELKKG IK+T Sbjct: 85 TIKNVREACESFEPGSIQYRPIGIALDTKGPEIRTGLIHGSGTAEVELKKGNVIKITLDD 144 Query: 475 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSV-------SADTLTCTIEN 633 Y EK + + +++DYKNIT VV G++I+IDDGLIS+ + + +D L C IEN Sbjct: 145 AYVEKCSEEILWLDYKNITKVVDVGSKIYIDDGLISLQVKEIGNSSISSGSDYLMCEIEN 204 Query: 634 GGMLGSRKGVNLPGIPVDLPAVSE 705 GG LGS+KGVNLPG VDLPAVS+ Sbjct: 205 GGTLGSKKGVNLPGAAVDLPAVSD 228 >UniRef50_P30613 Cluster: Pyruvate kinase isozymes R/L; n=167; Fungi/Metazoa group|Rep: Pyruvate kinase isozymes R/L - Homo sapiens (Human) Length = 574 Score = 242 bits (593), Expect = 5e-63 Identities = 117/200 (58%), Positives = 152/200 (76%), Gaps = 3/200 (1%) Frame = +1 Query: 115 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 294 L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE Sbjct: 70 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 129 Query: 295 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 465 +I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T Sbjct: 130 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 186 Query: 466 TSPDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 645 P ++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +ENGG+L Sbjct: 187 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 246 Query: 646 GSRKGVNLPGIPVDLPAVSE 705 GSRKGVNLPG VDLP +SE Sbjct: 247 GSRKGVNLPGAQVDLPGLSE 266 >UniRef50_Q9VD23 Cluster: Pyruvate kinase; n=5; Coelomata|Rep: Pyruvate kinase - Drosophila melanogaster (Fruit fly) Length = 744 Score = 198 bits (484), Expect = 8e-50 Identities = 90/156 (57%), Positives = 115/156 (73%), Gaps = 1/156 (0%) Frame = +1 Query: 241 MNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGG 420 M V RMNFSHGSHEYH +TI+ R+A Y + G P +LAIALDTKGPEIRTG L GG Sbjct: 1 MRVVRMNFSHGSHEYHCQTIQAARKAIAMYVEQTGLPRTLAIALDTKGPEIRTGKLAGGN 60 Query: 421 S-AEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQS 597 AE+ELK G+ + L+T + +K N D IYVDY+ + +VKPGNR+F+DDGLI++I + Sbjct: 61 DRAEIELKTGDKVTLSTKKEMADKSNKDNIYVDYQRLPQLVKPGNRVFVDDGLIALIVKE 120 Query: 598 VSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 D + C +ENGG LGS KG+NLPG+PVDLP+V+E Sbjct: 121 SKGDEVICQVENGGKLGSHKGINLPGVPVDLPSVTE 156 >UniRef50_Q27686 Cluster: Pyruvate kinase; n=16; Kinetoplastida|Rep: Pyruvate kinase - Leishmania mexicana Length = 499 Score = 193 bits (470), Expect = 4e-48 Identities = 99/199 (49%), Positives = 135/199 (67%), Gaps = 1/199 (0%) Frame = +1 Query: 109 SQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYH 288 SQL H L I + R + IICTIGP++++V L+ ++++GM+VARMNFSHGSHEYH Sbjct: 2 SQLAHNLTLSIFDPVANYRAARIICTIGPSTQSVEALKGLIQSGMSVARMNFSHGSHEYH 61 Query: 289 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 468 TI N R+A +A+LG ++AIALDTKGPEIRTG GG + +++G T +TT Sbjct: 62 QTTINNVRQA----AAELG--VNIAIALDTKGPEIRTGQFVGG---DAVMERGATCYVTT 112 Query: 469 SPDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQS-VSADTLTCTIENGGML 645 P + +KG D Y+DY+N++ VV+PGN I+IDDG++ + QS TL CT+ N + Sbjct: 113 DPAFADKGTKDKFYIDYQNLSKVVRPGNYIYIDDGILILQVQSHEDEQTLECTVTNSHTI 172 Query: 646 GSRKGVNLPGIPVDLPAVS 702 R+GVNLPG VDLPAVS Sbjct: 173 SDRRGVNLPGCDVDLPAVS 191 >UniRef50_Q9VQH0 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: Pyruvate kinase - Drosophila melanogaster (Fruit fly) Length = 554 Score = 176 bits (429), Expect = 4e-43 Identities = 88/207 (42%), Positives = 130/207 (62%) Frame = +1 Query: 85 KPTVANVGSQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNF 264 K + +QL H+C LD+ ++S+ RL +I TI +SRN + M+ G+N+ R+NF Sbjct: 6 KSVLKEGSTQLSHICELDLAQQASHQRLVSLIATISVSSRNADTIYTMIMRGVNIFRLNF 65 Query: 265 SHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKK 444 SH SHE H++TI EA + + G ++AIA DT+GP+IRTGLL+G +V L+ Sbjct: 66 SHESHEMHSKTIELINEALERIHKETGQIRTVAIAADTRGPQIRTGLLDG----DVFLRS 121 Query: 445 GETIKLTTSPDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCT 624 G+ ++L+ + D +KGN + +YVDY NI N+ K G+R+FIDDG + + V D L C Sbjct: 122 GDNLRLSINRDLYDKGNKEAVYVDYPNIINLTKTGDRLFIDDGRLLLHILEVGVDGLLCE 181 Query: 625 IENGGMLGSRKGVNLPGIPVDLPAVSE 705 + +GG L + V LP I +DLPAVSE Sbjct: 182 VIHGGQLNNNCNVILPEIEIDLPAVSE 208 >UniRef50_Q7RVA8 Cluster: Pyruvate kinase; n=11; Ascomycota|Rep: Pyruvate kinase - Neurospora crassa Length = 527 Score = 168 bits (409), Expect = 1e-40 Identities = 86/204 (42%), Positives = 128/204 (62%), Gaps = 2/204 (0%) Frame = +1 Query: 100 NVGSQLQHMCGLDIDSKSSY-IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGS 276 ++G ++Q + L+ + + + R + IICTIGP + +V + K+ + G+NV RMNFSHGS Sbjct: 10 SLGGKIQWLAQLNTEFQPAREFRRTSIICTIGPKTNSVEAINKLRDAGLNVVRMNFSHGS 69 Query: 277 HEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETI 456 +EYH I N R+AEK + G P +AIALDTKGPEIRTG + ++ + G + Sbjct: 70 YEYHQSVIDNARQAEKVHP---GRP--IAIALDTKGPEIRTGNTK--NDEDIPISAGTIL 122 Query: 457 KLTTSPDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISI-ICQSVSADTLTCTIEN 633 +TT Y+++ + +YVDY NIT V+ PG I++DDG+++ + + V T+ N Sbjct: 123 NITTDEKYKDECTIEHMYVDYVNITKVIAPGRIIYVDDGVLAFEVLEIVDDKTIKVKARN 182 Query: 634 GGMLGSRKGVNLPGIPVDLPAVSE 705 G + SRKGVNLP VDLPA+SE Sbjct: 183 NGYISSRKGVNLPNTDVDLPALSE 206 >UniRef50_Q42806 Cluster: Pyruvate kinase, cytosolic isozyme; n=62; Eukaryota|Rep: Pyruvate kinase, cytosolic isozyme - Glycine max (Soybean) Length = 511 Score = 162 bits (393), Expect = 9e-39 Identities = 83/179 (46%), Positives = 114/179 (63%), Gaps = 2/179 (1%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 I+CT+GPASR+V + EK++ GMNVAR NFSHG+H+YH ET+ N + +A + Sbjct: 25 IVCTLGPASRSVEMTEKLLRAGMNVARFNFSHGTHDYHQETLNNLK------TAMHNTGI 78 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 A+ LDTKGPEIRTG L+ G ++LK+G+ + +TT DY KG+ + I + YK + Sbjct: 79 LCAVMLDTKGPEIRTGFLKDG--KPIQLKEGQEVTITT--DYDIKGDPEMISMSYKKLPV 134 Query: 535 VVKPGNRIFIDDGLISIICQSVSAD--TLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 +KPGN I DG I++ S D T+ C EN LG RK VNLPG+ VDLP ++E Sbjct: 135 HLKPGNTILCSDGTITLTVLSCDPDAGTVRCRCENTATLGERKNVNLPGVVVDLPTLTE 193 >UniRef50_Q9M057 Cluster: Pyruvate kinase; n=11; Magnoliophyta|Rep: Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress) Length = 510 Score = 157 bits (380), Expect = 3e-37 Identities = 84/179 (46%), Positives = 114/179 (63%), Gaps = 2/179 (1%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 IICT+GP SR+V ++EK+++ GMNVAR NFSHGSH YH ET+ N R A + + Sbjct: 20 IICTLGPVSRSVEMIEKLLKAGMNVARFNFSHGSHSYHQETLDNLRTAMDN------TGI 73 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 A+ LDTKGPEIRTG L+ G ++L +G+ ++T S DY +G+++ I + YK + Sbjct: 74 LSAVMLDTKGPEIRTGFLKEG--KPIQLNQGQ--EITISIDYMIEGDSNVISMSYKKLAE 129 Query: 535 VVKPGNRIFIDDGLISIICQSV--SADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 VKPG+ I DG IS+ S S + C EN +LG RK VNLPGI VDLP ++E Sbjct: 130 DVKPGDVILCSDGTISLTVLSCDKSFGLVRCRCENSAILGERKNVNLPGIVVDLPTLTE 188 >UniRef50_Q8EX62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyruvate kinase - Leptospira interrogans Length = 486 Score = 152 bits (369), Expect = 7e-36 Identities = 78/186 (41%), Positives = 121/186 (65%) Frame = +1 Query: 145 SKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEK 324 S+SS R + IICTIGPA+ + +++ + E GMNVAR+N SHG+H++H IRN + K Sbjct: 3 SESSVFRKTKIICTIGPATSDKKMIQALAEAGMNVARLNMSHGNHDFHRSIIRNIKSLNK 62 Query: 325 SYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADT 504 L +P +AI LDT+GPEIRTG L+ ++LK GET P E+ + Sbjct: 63 DV---LKNP--IAILLDTQGPEIRTGDLQVD---HLDLKVGETFTFHIIPG--EESEEQS 112 Query: 505 IYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPV 684 ++V+YK+I +K G+ + +D+GLI+++ + ++ L C + +GG LGSRK +NLPGI V Sbjct: 113 VFVNYKDIVKDLKVGDPVTVDNGLINLVVEEINDSALKCKVLDGGRLGSRKHINLPGIRV 172 Query: 685 DLPAVS 702 +LP+++ Sbjct: 173 NLPSIT 178 >UniRef50_A4E9R2 Cluster: Pyruvate kinase; n=1; Collinsella aerofaciens ATCC 25986|Rep: Pyruvate kinase - Collinsella aerofaciens ATCC 25986 Length = 486 Score = 150 bits (364), Expect = 3e-35 Identities = 76/178 (42%), Positives = 114/178 (64%), Gaps = 1/178 (0%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 I+CT+GPA + + +M++ GMNVAR NFSHGS++ H I R K +LG P Sbjct: 7 IVCTMGPACDSDETIREMIKAGMNVARFNFSHGSYDEHHGRIERVRRISK----ELGLP- 61 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQE-KGNADTIYVDYKNIT 531 + I LDTKGPE+RTGLL G +V +K G+ I +T P ++ G A+ I +DY + Sbjct: 62 -VGILLDTKGPEVRTGLLVDG--KKVAVKTGDKIVVTAQPTSEDFHGTAEHISLDYLALP 118 Query: 532 NVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 + V+ G+ I IDDGL+++ +SV +TC ++N G++G RKGVN+P + + LPA++E Sbjct: 119 SEVEKGSLILIDDGLVALEVESVDGQDMTCVVKNDGLIGERKGVNMPNVNISLPAITE 176 >UniRef50_P77983 Cluster: Pyruvate kinase I; n=29; Bacteria|Rep: Pyruvate kinase I - Salmonella typhimurium Length = 470 Score = 147 bits (356), Expect = 3e-34 Identities = 77/177 (43%), Positives = 107/177 (60%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 I+CTIGP + + +L KM++ GMNV R+NFSHG + H + I+N R +K G Sbjct: 6 IVCTIGPKTESEEMLSKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNV----MSKTGK-- 59 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 AI LDTKGPEIRT LEGG +V LK G+T TT D GN + + V Y+ T+ Sbjct: 60 KAAILLDTKGPEIRTIKLEGGN--DVSLKAGQTFTFTT--DKSVVGNNEIVAVTYEGFTS 115 Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 + GN + +DDGLI + ++ + + C + N G LG KGVNLPG+ + LPA++E Sbjct: 116 DLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNLPGVSIALPALAE 172 >UniRef50_O44006 Cluster: Pyruvate kinase; n=10; cellular organisms|Rep: Pyruvate kinase - Eimeria tenella Length = 531 Score = 146 bits (354), Expect = 5e-34 Identities = 73/177 (41%), Positives = 107/177 (60%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 I+CT+GP+ +V + ++++ GMNV R+NFSHG HE H ++N +EA K K Sbjct: 60 IVCTMGPSCWDVDKMVQLIDAGMNVCRLNFSHGDHEAHGRVVKNLQEALKQRPGK----- 114 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 +A+ LDTKGPEIRTG+LEG +EL G+ +K+ T DY GN I Y+ + + Sbjct: 115 RVALLLDTKGPEIRTGMLEG--DKPIELHAGDMLKIVT--DYSFVGNKSCIACSYEKLPS 170 Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 VKPGN I I DG +S+ D + + N ++G++K +NLPG+ VDLP + E Sbjct: 171 SVKPGNTILIADGSLSVEVVECGKDYVMTRVMNPAIIGNKKNMNLPGVKVDLPVIGE 227 >UniRef50_P80885 Cluster: Pyruvate kinase; n=161; Bacteria|Rep: Pyruvate kinase - Bacillus subtilis Length = 585 Score = 145 bits (352), Expect = 8e-34 Identities = 83/184 (45%), Positives = 117/184 (63%), Gaps = 2/184 (1%) Frame = +1 Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339 +R + I+CTIGPAS ++ +L K+ME+GMNVAR+NFSHG E H I+N REA K K Sbjct: 1 MRKTKIVCTIGPASESIEMLTKLMESGMNVARLNFSHGDFEEHGARIKNIREASK----K 56 Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519 LG ++ I LDTKGPEIRT +E GG +EL+ G+ +L S D + G D I V Y Sbjct: 57 LGK--NVGILLDTKGPEIRTHTMENGG---IELETGK--ELIISMD-EVVGTTDKISVTY 108 Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSA--DTLTCTIENGGMLGSRKGVNLPGIPVDLP 693 + + + V+ G+ I +DDGLI + V A + + N G L ++KGVN+PG+ V+LP Sbjct: 109 EGLVHDVEQGSTILLDDGLIGLEVLDVDAAKREIKTKVLNNGTLKNKKGVNVPGVSVNLP 168 Query: 694 AVSE 705 ++E Sbjct: 169 GITE 172 >UniRef50_Q2TSW8 Cluster: Pyruvate kinase; n=4; stramenopiles|Rep: Pyruvate kinase - Phaeodactylum tricornutum Length = 543 Score = 145 bits (351), Expect = 1e-33 Identities = 78/183 (42%), Positives = 111/183 (60%), Gaps = 2/183 (1%) Frame = +1 Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342 R + I+CTIGPA NV LE ++E+GMNVAR NFSHG H H + R+A ++ Sbjct: 31 RRTKIVCTIGPACWNVDQLEILIESGMNVARFNFSHGDHAGHGAVLERVRQAAQNKGR-- 88 Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522 ++AI LDTKGPEIRTG G S ++EL KGETI LT+ DY+ KG+ + Y Sbjct: 89 ----NIAILLDTKGPEIRTGFFANGAS-KIELVKGETIVLTS--DYKFKGDQHKLACSYP 141 Query: 523 NITNVVKPGNRIFIDDG--LISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPA 696 + V G +I + DG +++++ +A ++C I+N +G RK +NLPG+ VDLP Sbjct: 142 ALAQSVTQGQQILVADGSLVLTVLQTDEAAGEVSCRIDNNASMGERKNMNLPGVKVDLPT 201 Query: 697 VSE 705 +E Sbjct: 202 FTE 204 >UniRef50_Q1FK29 Cluster: Pyruvate kinase; n=4; Clostridiales|Rep: Pyruvate kinase - Clostridium phytofermentans ISDg Length = 580 Score = 141 bits (342), Expect = 1e-32 Identities = 75/182 (41%), Positives = 111/182 (60%) Frame = +1 Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339 +R + I+CT+GPA+ + AVL ++M GM+VAR NFSHG +E H R SA+ Sbjct: 1 MRKTKIVCTLGPATEDDAVLRQLMIEGMDVARFNFSHGDYEQHTRNYERIRRL----SAE 56 Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519 L P +A LDTKGPEIR G E G ++ELKKG+ LTT+ G+ + + Y Sbjct: 57 LKLP--IATLLDTKGPEIRIGTFENG---KIELKKGQIFTLTTNDIV---GDETQVSITY 108 Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699 KN+ +K G +I IDDGLI + +++ + C + NGGM+ + KGVN+PG+ + +P + Sbjct: 109 KNLIRDIKNGVKILIDDGLIELKVFNITDTDIICEVLNGGMISNHKGVNVPGVELSMPFI 168 Query: 700 SE 705 S+ Sbjct: 169 SK 170 >UniRef50_Q2TSW6 Cluster: Pyruvate kinase; n=1; Achlya bisexualis|Rep: Pyruvate kinase - Achlya bisexualis (Water mold) Length = 517 Score = 140 bits (338), Expect = 4e-32 Identities = 71/189 (37%), Positives = 114/189 (60%), Gaps = 3/189 (1%) Frame = +1 Query: 145 SKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEK 324 SK+ ++ I+ T+GP S N +++ G+ + R+NFSH +++ + + R ++ Sbjct: 23 SKNDAFSMTKIVGTVGPVSENAKTTQELTNAGLKIMRINFSHATYDEAHLRMSHLRASKG 82 Query: 325 SYSAKLGSPFSL-AIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNAD 501 ++ G F++ A+ LDT+GPEIR G ++ L KG+ I LTT Y+E D Sbjct: 83 VHAKHTGKEFNVRAVLLDTQGPEIRGGAFP---EKKINLTKGDMITLTTDVQYKEASTKD 139 Query: 502 TIYVDYKNITNVVKPGNRIFIDDGLISIICQS--VSADTLTCTIENGGMLGSRKGVNLPG 675 +YV Y+ + VK G+ + +DDGLIS+ +S V++ + C IEN +LGSRKGVNLPG Sbjct: 140 MLYVTYEQLPATVKVGDTVLLDDGLISLTVKSIDVASGQVRCLIENSEVLGSRKGVNLPG 199 Query: 676 IPVDLPAVS 702 + VDLPA++ Sbjct: 200 LVVDLPALT 208 >UniRef50_P52489 Cluster: Pyruvate kinase 2; n=33; Dikarya|Rep: Pyruvate kinase 2 - Saccharomyces cerevisiae (Baker's yeast) Length = 506 Score = 138 bits (335), Expect = 9e-32 Identities = 75/199 (37%), Positives = 111/199 (55%), Gaps = 1/199 (0%) Frame = +1 Query: 109 SQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYH 288 S+LQ + L I + +R + II TIGP + + + + + G+N+ R+NFSHGS+E+H Sbjct: 4 SRLQRLANLKIGTPQQ-LRRTSIIGTIGPKTNSCEAITALRKAGLNIIRLNFSHGSYEFH 62 Query: 289 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 468 I N ++E+ + G P LAIALDTKGPEIRTG ++ + + TT Sbjct: 63 QSVIENAVKSEQQFP---GRP--LAIALDTKGPEIRTG--RTLNDQDLYIPVDHQMIFTT 115 Query: 469 SPDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGML 645 + N +Y+DY N+T V+ PG I++DDG++S + Q + L N G + Sbjct: 116 DASFANTSNDKIMYIDYANLTKVIVPGRFIYVDDGILSFKVLQIIDESNLRVQAVNSGYI 175 Query: 646 GSRKGVNLPGIPVDLPAVS 702 S KGVNLP VDLP +S Sbjct: 176 ASHKGVNLPNTDVDLPPLS 194 >UniRef50_Q22Z06 Cluster: Pyruvate kinase family protein; n=3; Oligohymenophorea|Rep: Pyruvate kinase family protein - Tetrahymena thermophila SB210 Length = 505 Score = 138 bits (334), Expect = 1e-31 Identities = 71/181 (39%), Positives = 107/181 (59%) Frame = +1 Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342 R + I+CTIGP+ + L +++E GMNVAR+NFSHG H H ET+R +EA K+ Sbjct: 22 RKTKIVCTIGPSCWDHDNLVQLLENGMNVARLNFSHGDHAGHGETVRRLKEAFKA----- 76 Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522 A+ LDTKGPEIRTGL++ + L G+ +++TT DY G+ + YK Sbjct: 77 RKNIQCALMLDTKGPEIRTGLVKDQTKKLINLVAGQELEITT--DYSVLGDEKVLACSYK 134 Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702 ++ VK G ++ I DG + I + + D++ ++N +G +K +NLPG VDLP V+ Sbjct: 135 SLPKSVKVGGQVLIADGTLVCIVKEIKQDSIIVNVQNTCSIGEKKNMNLPGAIVDLPTVT 194 Query: 703 E 705 E Sbjct: 195 E 195 >UniRef50_Q4U977 Cluster: Pyruvate kinase, putative; n=3; Piroplasmida|Rep: Pyruvate kinase, putative - Theileria annulata Length = 513 Score = 136 bits (330), Expect = 4e-31 Identities = 72/177 (40%), Positives = 106/177 (59%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 I+CT+GPA NV + +M+++GMN+ R NFSHG+HE H +T+ +EA KS Sbjct: 42 IVCTMGPACGNVETIIQMVKSGMNICRFNFSHGNHETHTKTLNLVKEALKSVPEA----- 96 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 ++ + LDTKGPEIRTG L+ + L++G T+K+TT DY +G+ I YK + Sbjct: 97 NIGLMLDTKGPEIRTGFLK--NHTPITLEEGSTLKITT--DYTIEGDETIISCSYKKLPQ 152 Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 VK GN I I DG +S +V D + + N +G K +NLPG+ V+LP ++E Sbjct: 153 SVKVGNIILIADGSLSCEVLAVFDDYIEVKVLNNAKIGEYKNMNLPGVKVELPVLTE 209 >UniRef50_Q9KUN0 Cluster: Pyruvate kinase; n=24; cellular organisms|Rep: Pyruvate kinase - Vibrio cholerae Length = 470 Score = 135 bits (327), Expect = 9e-31 Identities = 75/177 (42%), Positives = 102/177 (57%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 I+CTIGP + +V L +++ GMNV R+NFSHG + H I N R+ + +L Sbjct: 6 IVCTIGPKTESVEKLTELVNAGMNVMRLNFSHGDYVEHGTRITNFRKVMEVTGKQL---- 61 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 AI LDTKGPEIRT LE G +V+L G+ TT D + GN + + V Y Sbjct: 62 --AILLDTKGPEIRTIKLENGD--DVDLVAGQEFTFTT--DTKVVGNKERVAVTYSGFAK 115 Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 + GNRI +DDGLI + + + + C + N G LG KGVNLPG+ V+LPA+SE Sbjct: 116 DLNVGNRILVDDGLIEMEVLATTDTEVKCKVLNNGALGENKGVNLPGVSVNLPALSE 172 >UniRef50_Q747D6 Cluster: Pyruvate kinase; n=6; Desulfuromonadales|Rep: Pyruvate kinase - Geobacter sulfurreducens Length = 480 Score = 133 bits (321), Expect = 5e-30 Identities = 73/181 (40%), Positives = 110/181 (60%) Frame = +1 Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342 R + II T+GP S + ++ ++M+ G++V R+NFSHGS++ E I R SA+ Sbjct: 6 RKTKIIATLGPVSSSPDMIRQLMDAGVDVFRLNFSHGSNDQRREVIAAIRRL----SAER 61 Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522 G + I D +GP+IRTG +E G + L +G+++ +TT G TIY + Sbjct: 62 GK--EIGILADLQGPKIRTGRMENGA---IPLVRGDSLDITTDEVLGRPGLISTIY---Q 113 Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702 ++ + VKPG+RI +DDGLI + QSVS T+ CT+ GGML KG+NLPG+ V P++S Sbjct: 114 SLPHDVKPGSRILLDDGLIELRVQSVSGATVRCTVVQGGMLKDLKGINLPGVKVSAPSLS 173 Query: 703 E 705 E Sbjct: 174 E 174 >UniRef50_Q55863 Cluster: Pyruvate kinase 1; n=5; Cyanobacteria|Rep: Pyruvate kinase 1 - Synechocystis sp. (strain PCC 6803) Length = 483 Score = 131 bits (316), Expect = 2e-29 Identities = 71/176 (40%), Positives = 108/176 (61%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 I+ TIGPAS +V V+ +M++ GMNVAR+NFSHGS+E HA +R R E+ ++ +P Sbjct: 20 IVATIGPASSSVEVIRQMVDAGMNVARLNFSHGSYEDHATMVRLLRSVEQ----EMDTPI 75 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 +L D +GP+IR G L GG E +L++GE + L P + + +DY ++ Sbjct: 76 TL--LQDLQGPKIRIGQLPGG---EKQLREGEKVSLV--PVEIGDRHPGAVGIDYPHLAT 128 Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702 K G RI +DDGL+ + S+ + C + GG+L SRKGVNLPG+ + LP+++ Sbjct: 129 EAKVGERILLDDGLLEMKVVSIQDPEVICEVVTGGILKSRKGVNLPGLVLTLPSMT 184 >UniRef50_Q8TJ98 Cluster: Pyruvate kinase; n=2; Methanomicrobia|Rep: Pyruvate kinase - Methanosarcina acetivorans Length = 489 Score = 130 bits (315), Expect = 2e-29 Identities = 72/177 (40%), Positives = 101/177 (57%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 I+CTIGPAS + VL K++ GMNVAR+NFSHG E H + IR R+ + Sbjct: 22 IVCTIGPASFSEEVLRKLVLAGMNVARINFSHGDFESHGKVIRRVRKVAEELDR------ 75 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 ++AI D GP+IR G L+ + L KG I LTT + G+ D I V+YK + Sbjct: 76 TVAILADLPGPKIRVGKLK---KEPLMLHKGNRITLTTD---ETSGSEDRIPVNYKQLPE 129 Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 V PG+ I++ DG I ++C +S + C + GG L S KG+NLPG + L +V+E Sbjct: 130 SVSPGSLIYLSDGFIQLLCLEISGKDVVCEVMVGGQLYSHKGLNLPGAKIYLDSVTE 186 >UniRef50_Q46078 Cluster: Pyruvate kinase; n=19; Actinobacteria (class)|Rep: Pyruvate kinase - Corynebacterium glutamicum (Brevibacterium flavum) Length = 475 Score = 130 bits (314), Expect = 3e-29 Identities = 65/181 (35%), Positives = 104/181 (57%) Frame = +1 Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342 R + I+CT+GPA + + +++E GM+VAR+NFSHG H H + + REA + + Sbjct: 3 RRTKIVCTLGPAVASADGILRLVEDGMDVARLNFSHGDHPDHEQNYKWVREAAEKTGRAV 62 Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522 G I D +GP+IR G G + + GETI++T +G D + YK Sbjct: 63 G------ILADLQGPKIRLGRFTDGATV---WENGETIRITVD---DVEGTHDRVSTTYK 110 Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702 N+ KPG+R+ +DDG + ++C SV + + C + GG + + KGV+LPG+ + +PA+S Sbjct: 111 NLAKDAKPGDRLLVDDGKVGLVCVSVEGNDVICEVVEGGPVSNNKGVSLPGMDISVPALS 170 Query: 703 E 705 E Sbjct: 171 E 171 >UniRef50_A3I0G9 Cluster: Pyruvate kinase; n=3; Flexibacteraceae|Rep: Pyruvate kinase - Algoriphagus sp. PR1 Length = 476 Score = 129 bits (312), Expect = 6e-29 Identities = 69/177 (38%), Positives = 97/177 (54%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 I+ TIGPAS N + + G NV R+NFSHGSH+ H E I R+ K + LG Sbjct: 11 ILATIGPASNNYETISSLAAAGANVFRLNFSHGSHDIHQEVIEIIRKINKEQNLNLG--- 67 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 I D +GP+IR G +E G VE+K GE I +T P G + + Y+N+ Sbjct: 68 ---ILQDLQGPKIRVGEVENNG---VEIKPGEKITITNDPVV---GTSTLVSTVYQNLPQ 118 Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 V G+RI IDDG + ++ + CT+ +GG+L SRKG+NLP V P+++E Sbjct: 119 DVVSGDRILIDDGNLEVVVNDTDGKNVNCTVIHGGILKSRKGINLPNTKVSAPSLTE 175 >UniRef50_Q8PYY4 Cluster: Pyruvate kinase; n=3; Methanosarcinaceae|Rep: Pyruvate kinase - Methanosarcina mazei (Methanosarcina frisia) Length = 477 Score = 129 bits (311), Expect = 8e-29 Identities = 74/177 (41%), Positives = 102/177 (57%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 I+CTIGPAS + ++ K+M GMNVAR+NFSHG E H+ +R R+ + +LG Sbjct: 10 IVCTIGPASSSEEMIRKLMLAGMNVARINFSHGDFESHSRVVRIIRKV----ADELGR-- 63 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 ++AI D GP+IR G LE V L KG I LT GN + I V YK + Sbjct: 64 TIAILADLPGPKIRIGKLE---KEPVMLHKGNPITLTID---DTPGNEERIPVSYKQLPE 117 Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 V PG+ I++ DG I ++C+ V+ + C + GG L S KG+NLPG + L AV+E Sbjct: 118 SVTPGSLIYLSDGFIQLLCKEVTGKDVLCEVLIGGELYSHKGLNLPGAKIFLDAVTE 174 >UniRef50_Q090R5 Cluster: Pyruvate kinase; n=1; Stigmatella aurantiaca DW4/3-1|Rep: Pyruvate kinase - Stigmatella aurantiaca DW4/3-1 Length = 515 Score = 128 bits (309), Expect = 1e-28 Identities = 74/182 (40%), Positives = 108/182 (59%), Gaps = 1/182 (0%) Frame = +1 Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339 +R + I+CT+GPAS++ +LE ++E GM+VAR+NFSHGSHE HAE I R A S K Sbjct: 10 MRRAKIVCTLGPASQSQDMLEALIEAGMDVARLNFSHGSHEQHAENIAKLRAA----SLK 65 Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519 L ++ I D +GP+IRTG G + LK+G +TT D KGN D + Y Sbjct: 66 LRK--AVGILGDLQGPKIRTGRFITGSTV---LKEGAIFSITT--DESVKGNDDIVSTTY 118 Query: 520 KNITNVVKPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPA 696 ++ V PG+RI +DDGL+ + + ++ L + GG L + KG+NLPG+ V A Sbjct: 119 AHLAADVNPGDRILLDDGLLELKVLETDKKQLLRTQVVIGGTLKNNKGINLPGVAVRADA 178 Query: 697 VS 702 ++ Sbjct: 179 LT 180 >UniRef50_Q81N35 Cluster: Pyruvate kinase; n=11; Bacillus cereus group|Rep: Pyruvate kinase - Bacillus anthracis Length = 352 Score = 127 bits (307), Expect = 2e-28 Identities = 68/176 (38%), Positives = 102/176 (57%) Frame = +1 Query: 178 ICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 357 +CTIGPAS N L K++ GM + R+N SHG+HE H + IR + + S Sbjct: 6 VCTIGPASNNKETLAKLINNGMKIVRLNLSHGTHESHKDIIRLVKSLDDS---------- 55 Query: 358 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITNV 537 + I D +GP+IR G ++G ++ L+ G++ L T P G++ VDY+ I N Sbjct: 56 IKILGDVQGPKIRLGEIKG---EQITLQAGDSFMLRTQP---VTGSSTEASVDYEGIAND 109 Query: 538 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 VK G+RI ++DG + +I + VS D + ++ GG + S KGVNLPG V LPA++E Sbjct: 110 VKVGSRILMNDGEVELIVEKVSTDKIETKVKTGGNISSHKGVNLPGAIVSLPAITE 165 >UniRef50_A7HIL5 Cluster: Pyruvate kinase; n=9; Bacteria|Rep: Pyruvate kinase - Anaeromyxobacter sp. Fw109-5 Length = 491 Score = 126 bits (304), Expect = 5e-28 Identities = 69/182 (37%), Positives = 106/182 (58%) Frame = +1 Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339 +R + I+ T+GPAS + VL++M+ G++VAR+NFSHG HE HA+ + R A S Sbjct: 4 MRRAKIVATLGPASSDPDVLQRMLAAGVDVARLNFSHGRHEDHAQMLDRIRTA----SRH 59 Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519 LG ++A+ D +GP+IRTG L G V L+ G + + T D + KG+A + Y Sbjct: 60 LGR--AVAVLQDLQGPKIRTGPLAAGREG-VRLEAGAELVIAT--DAEVKGDAKLVSTTY 114 Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699 ++ V+PG+R+ +DDGLI + C + GG+L KG+NLPG+ + A+ Sbjct: 115 PHLAEDVRPGDRLLVDDGLIELRVLETDGVRARCQVVEGGVLREHKGINLPGVALRAEAL 174 Query: 700 SE 705 SE Sbjct: 175 SE 176 >UniRef50_Q6MLB5 Cluster: Pyruvate kinase; n=1; Bdellovibrio bacteriovorus|Rep: Pyruvate kinase - Bdellovibrio bacteriovorus Length = 495 Score = 123 bits (296), Expect = 5e-27 Identities = 69/177 (38%), Positives = 102/177 (57%), Gaps = 2/177 (1%) Frame = +1 Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342 R + I+ TIGPA+R+ LEK ++ GMNVAR+NFSHGSHE H + + + R+ K A Sbjct: 5 RRAKIVATIGPATRDEKNLEKAIKAGMNVARLNFSHGSHEDHLKVVHSLRKLSKELQA-- 62 Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522 +AI D +GP+IR G E G +E+K GE + +TT+ + G + D++ Sbjct: 63 ----PVAILQDLQGPKIRVGKFENG---SIEIKPGEKLVVTTA---KVLGKPGLVPSDFQ 112 Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGI--PVD 687 + PG RI +DDGL+ + V + + + GG+L RKG+NLPG+ PVD Sbjct: 113 ELPLACVPGTRILLDDGLMEVKVLQVRGEEIDVEVVYGGILKDRKGMNLPGVNLPVD 169 >UniRef50_Q1K4D5 Cluster: Pyruvate kinase; n=1; Desulfuromonas acetoxidans DSM 684|Rep: Pyruvate kinase - Desulfuromonas acetoxidans DSM 684 Length = 474 Score = 122 bits (295), Expect = 7e-27 Identities = 69/182 (37%), Positives = 108/182 (59%) Frame = +1 Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339 +R + I+CT+GPAS + A LE+M+ +GMNVAR+NFSHG H+ H + I R K + Sbjct: 1 MRRTKIVCTVGPASADEATLEQMISSGMNVARLNFSHGDHDSHQQLIERIRAVAK----R 56 Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519 L P +AI D GP+IR G L G V L +G+ + L ++ + G D + VDY Sbjct: 57 LNQP--VAILQDLCGPKIRLGQLPEQG---VRLHQGDAVSLCST---GQAGEGD-LPVDY 107 Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699 ++ V+ G+ I + DGL+ + + + A + C++ +GG+ SRKGVN+P + +PA Sbjct: 108 PSLHEDVQVGDSIMLSDGLMELQVERIDAPQVQCSVISGGVAYSRKGVNMPSSHLSIPAF 167 Query: 700 SE 705 +E Sbjct: 168 TE 169 >UniRef50_Q08SK3 Cluster: Pyruvate kinase; n=2; Cystobacterineae|Rep: Pyruvate kinase - Stigmatella aurantiaca DW4/3-1 Length = 481 Score = 122 bits (294), Expect = 9e-27 Identities = 69/182 (37%), Positives = 105/182 (57%) Frame = +1 Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339 +R + IICT+GPAS V+E ++ GMNVAR+NFSHG +E H + R+ S K Sbjct: 16 MRKAKIICTLGPASDTPEVIEGLVRAGMNVARINFSHGVYEDHRRRVNTLRKV----SRK 71 Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519 LG P +AI D +GP+IR G EGG ++ ++ G+T+ +TT G I Sbjct: 72 LGIP--VAILQDIQGPKIRLGRFEGG---QLLVQAGQTVTVTTR---AVLGQGTLIPTPV 123 Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699 +++T V G+ I +DDG + + V+ +T T+E GG+L KG+NLPG + +P + Sbjct: 124 RSLTRDVTRGDMILLDDGRVRLRVVRVAGRDVTATVEVGGLLKDHKGLNLPGAAISVPTI 183 Query: 700 SE 705 +E Sbjct: 184 TE 185 >UniRef50_Q2S3S2 Cluster: Pyruvate kinase; n=1; Salinibacter ruber DSM 13855|Rep: Pyruvate kinase - Salinibacter ruber (strain DSM 13855) Length = 476 Score = 121 bits (291), Expect = 2e-26 Identities = 62/181 (34%), Positives = 102/181 (56%) Frame = +1 Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342 R + I+CT+GPA+ + L +++ GM+VARMNFSHG+HE H E + RE ++ Sbjct: 3 RRTKIVCTLGPATTDPETLRRLVAAGMDVARMNFSHGTHEEHRERVETVREVAEAEGK-- 60 Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522 + + D +GP+IR G ++ + V L +G+ ++++T D + + I++DY+ Sbjct: 61 ----GITVLQDLQGPKIRVGAVQ---NDSVMLAEGDEVRVST--DTPRESTNEHIFIDYE 111 Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702 + + G RI IDDGL+ + + L T+ GG L SRKGVNLP + P ++ Sbjct: 112 ALARDAREGERILIDDGLLELRVIETNGSQLRATVVEGGPLRSRKGVNLPDLQASTPPMT 171 Query: 703 E 705 E Sbjct: 172 E 172 >UniRef50_Q2IHE2 Cluster: Pyruvate kinase; n=1; Anaeromyxobacter dehalogenans 2CP-C|Rep: Pyruvate kinase - Anaeromyxobacter dehalogenans (strain 2CP-C) Length = 489 Score = 120 bits (289), Expect = 3e-26 Identities = 66/182 (36%), Positives = 106/182 (58%) Frame = +1 Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339 +R + I+ T+GPAS VL +++E G++VAR+NFSHG HE HA + R A S Sbjct: 1 MRRAKIVATLGPASGEPDVLARLLEQGVDVARLNFSHGRHEDHARMLDKIRAA----SRH 56 Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519 LG ++A+ D +GP+IRTG L+ G A V+++ G+ + +TT + G+A + Y Sbjct: 57 LGK--AVAVLQDLQGPKIRTGPLK-AGKAGVQVEAGQELVITTEGEL--PGDAHLVSTTY 111 Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699 ++ V+ G+R+ +DDGL+ + + + GG LG KG+NLPG+ + A+ Sbjct: 112 PHLAEDVRAGDRLLVDDGLLEFRVLATDGVRVRTEVVEGGWLGEHKGINLPGVALRAEAL 171 Query: 700 SE 705 SE Sbjct: 172 SE 173 >UniRef50_Q3JCE7 Cluster: Pyruvate kinase; n=1; Nitrosococcus oceani ATCC 19707|Rep: Pyruvate kinase - Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848) Length = 492 Score = 120 bits (288), Expect = 5e-26 Identities = 70/181 (38%), Positives = 105/181 (58%) Frame = +1 Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342 R I+CTIGPASR+ A+L KM+ +GMNVAR+NFSHG+HE H REA + +L Sbjct: 24 RACRIVCTIGPASRSPAILRKMLLSGMNVARLNFSHGNHESHGRIACEIREA----AQRL 79 Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522 P +AI D +G ++R G ++ S + L++G+ I L + E ++ I +DY+ Sbjct: 80 MKP--VAILQDLQGHKVRVGKVQHPPS--LSLEEGQEILL----GHGETISSKRIGIDYQ 131 Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702 +I V PG ++F+DD I + S+ L C ++ GG L SRKGV P + P ++ Sbjct: 132 DIIQYVTPGQKVFLDDASIELEVLSIEEKDLHCQVKFGGQLRSRKGVIFPDSQLSFPLLN 191 Query: 703 E 705 E Sbjct: 192 E 192 >UniRef50_Q6A9P1 Cluster: Pyruvate kinase; n=4; Actinomycetales|Rep: Pyruvate kinase - Propionibacterium acnes Length = 477 Score = 118 bits (285), Expect = 1e-25 Identities = 65/185 (35%), Positives = 106/185 (57%), Gaps = 3/185 (1%) Frame = +1 Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339 +R + I+ T+GPA + ++++ME GMN+AR+N SHG + H E + + +S S + Sbjct: 1 MRRAKIVNTLGPAVTSHDAMKELMEAGMNIARLNMSHGDYSEHQERL----DLVRSVSKE 56 Query: 340 LGSPFSLAIALDTKGPEIRTGLLE---GGGSAEVELKKGETIKLTTSPDYQEKGNADTIY 510 LG ++A D +GP+IRTGL E G + +++LK G+ +TT GN + + Sbjct: 57 LG--LNVAALADLQGPKIRTGLFEKAEGESNGKIDLKIGDKFTITTDDIV---GNQERVS 111 Query: 511 VDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDL 690 +K + KPG+ I IDDG + SVS + + C G +G KG+NLPG+ V + Sbjct: 112 TTFKGLPQDCKPGDVILIDDGKTVLQVDSVSGNDVNCHCTVAGPVGDHKGINLPGVAVSI 171 Query: 691 PAVSE 705 PA+++ Sbjct: 172 PALTK 176 >UniRef50_O06134 Cluster: Pyruvate kinase; n=29; Bacteria|Rep: Pyruvate kinase - Mycobacterium tuberculosis Length = 472 Score = 118 bits (285), Expect = 1e-25 Identities = 60/181 (33%), Positives = 99/181 (54%) Frame = +1 Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342 R I+CT+GPA++ ++ ++E GM+VARMNFSHG ++ H R A + + Sbjct: 3 RRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAV 62 Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522 G + D +GP+IR G G + E GET+++T +G+ D + YK Sbjct: 63 G------VLADLQGPKIRLGRFASGATHWAE---GETVRITVGAC---EGSHDRVSTTYK 110 Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702 + G+R+ +DDG ++++ +V D + CT+ GG + KG++LPG+ V PA+S Sbjct: 111 RLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALS 170 Query: 703 E 705 E Sbjct: 171 E 171 >UniRef50_Q5V4I8 Cluster: Pyruvate kinase; n=4; Halobacteriaceae|Rep: Pyruvate kinase - Haloarcula marismortui (Halobacterium marismortui) Length = 610 Score = 118 bits (284), Expect = 1e-25 Identities = 65/182 (35%), Positives = 102/182 (56%) Frame = +1 Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339 +R + I+CT+GPAS +V + + + GM+VAR+N SHGS E+ E I R+ +++ Sbjct: 15 MRSAKIVCTLGPASDSVDDIASLAKAGMSVARLNASHGSPEHRREMIDRIRQVDEAVEEP 74 Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519 + A LD GPE+RT ++ ++L +G TI+ D A V Sbjct: 75 V------AAMLDMPGPEVRTAEID----EPIQLTEGSTIRYVVGDD------ATPEEVGL 118 Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699 V+PG+R+ +DDG I + V +T+ T+ENGG L +RKGVN+PG+ +DLP + Sbjct: 119 SQSITAVEPGDRVLLDDGRIETTVERVEDETVFATVENGGELAARKGVNVPGVELDLPTI 178 Query: 700 SE 705 +E Sbjct: 179 TE 180 >UniRef50_A7CUA8 Cluster: Pyruvate kinase; n=1; Opitutaceae bacterium TAV2|Rep: Pyruvate kinase - Opitutaceae bacterium TAV2 Length = 480 Score = 118 bits (283), Expect = 2e-25 Identities = 65/184 (35%), Positives = 109/184 (59%), Gaps = 2/184 (1%) Frame = +1 Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339 IR + I+ T+GPA+ + +LEK++ G +VAR+N +H +HE+ IR RE K + Sbjct: 10 IRRTKIVFTLGPATESEEMLEKLIRAGADVARLNMAHANHEWTRMIIRRIREVSK----R 65 Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNAD--TIYV 513 +G +AI +D KGPEIRTG + S+ +ELK GE T P + + + ++ V Sbjct: 66 VGR--EIAIMMDIKGPEIRTGDV----SSPIELKAGEIFDFTIRPGAAQDSSEEVRSVDV 119 Query: 514 DYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLP 693 +YK++ N ++ G+ + +D+GLI + + C + G L SR+ +NLPG+ V+LP Sbjct: 120 NYKDLVNDIRVGDTVLVDNGLIRLEVLEKQNTRIRCRVLIPGELKSRRHINLPGVKVNLP 179 Query: 694 AVSE 705 +++E Sbjct: 180 SLTE 183 >UniRef50_Q0W8N0 Cluster: Pyruvate kinase; n=7; cellular organisms|Rep: Pyruvate kinase - Uncultured methanogenic archaeon RC-I Length = 583 Score = 117 bits (282), Expect = 2e-25 Identities = 66/182 (36%), Positives = 100/182 (54%) Frame = +1 Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339 +R + I+CTIGPA + +LEK+ GMNVAR+N SH HE+ +TI N R S Sbjct: 1 MRKTKIVCTIGPACDSQDMLEKLAVAGMNVARLNMSHADHEHTVQTINNIR----MVSEA 56 Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519 +G P + I +D +GP+IR G L+ LK G T LTT G++ + V + Sbjct: 57 IGKP--IGILMDLQGPKIRVGTLQ----QPANLKPGGTFTLTTR---DVPGDSQEVNVPF 107 Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699 K + V G + +DDGLI + +V+ + + GG L S+KG+NLP + +P++ Sbjct: 108 KELPQSVSTGQTLLLDDGLIELKVDAVTETDIRTKVVRGGELKSKKGINLPQSTIRIPSI 167 Query: 700 SE 705 +E Sbjct: 168 TE 169 >UniRef50_A5C814 Cluster: Pyruvate kinase; n=1; Vitis vinifera|Rep: Pyruvate kinase - Vitis vinifera (Grape) Length = 621 Score = 116 bits (279), Expect = 6e-25 Identities = 63/181 (34%), Positives = 107/181 (59%) Frame = +1 Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342 R + I+CTIGP++ + ++ K+ ETGMNVAR+N SHG H H +TI +E + K+ Sbjct: 166 RKTKIVCTIGPSTSSREMIWKLAETGMNVARLNMSHGDHASHKKTIDLVKEYNAQFEDKV 225 Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522 +AI LDTKGPE+R+G + + LK+G+ T + + +T+ V+Y Sbjct: 226 -----IAIMLDTKGPEVRSGDV----PKPIMLKEGQEFNFTIK---RGVSSENTVSVNYD 273 Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702 + N V+ G+ + +D G++S+ +S S D + C + +GG L SR+ +N+ G LP+++ Sbjct: 274 DFVNDVEVGDILLVDGGMMSLAVKSKSKDLVKCQVIDGGELKSRRHLNVRGKSATLPSIT 333 Query: 703 E 705 + Sbjct: 334 D 334 >UniRef50_Q1IJ65 Cluster: Pyruvate kinase; n=6; Bacteria|Rep: Pyruvate kinase - Acidobacteria bacterium (strain Ellin345) Length = 485 Score = 115 bits (277), Expect = 1e-24 Identities = 63/177 (35%), Positives = 104/177 (58%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 I+ TIGPAS + +LE+++ TG++VAR+NFSHG H E I N R A S + G Sbjct: 10 IVGTIGPASESPEMLERLIRTGLDVARLNFSHGDFSGHRERIANLRAA----SDRAGR-- 63 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 ++A+ D GP++R G ++ + + L+ G+ LTT G+ + + + Sbjct: 64 AVAVLADLPGPKMRLGTIQ---NEPIHLRAGDPFTLTTDSIV---GDNRRCSMSFAALPQ 117 Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 VVKPG+R++++DGL+ ++ + + + C + GG L SRKG+NLPGI + + A +E Sbjct: 118 VVKPGDRLYLNDGLVHLLVERIEGTDVHCVVAVGGELRSRKGLNLPGINLGISAFTE 174 >UniRef50_Q1IHI1 Cluster: Pyruvate kinase; n=2; Bacteria|Rep: Pyruvate kinase - Acidobacteria bacterium (strain Ellin345) Length = 509 Score = 115 bits (276), Expect = 1e-24 Identities = 62/180 (34%), Positives = 99/180 (55%) Frame = +1 Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342 R + I+CTIGPA A ++++M GM+VAR+NFSHG+H+ H I+ R+ Sbjct: 20 RRAKIVCTIGPACNTEAAMQELMRAGMDVARLNFSHGTHDEHLVVIQRLRKVAAEEQR-- 77 Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522 S+ I D +GP+IRTGLL+ V L+ G T+ +T G+A + ++ Sbjct: 78 ----SICILQDLQGPKIRTGLLK--DHKPVMLETGNTVTITPR---DIVGDASLLATTFQ 128 Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702 + V+PG+RI + DG I + + + C I NGG L +G+N+PG + +PA++ Sbjct: 129 TLALDVQPGSRILLSDGKIELSVSRIEGADVECHIVNGGELKEHQGINIPGAILSIPALT 188 >UniRef50_Q56301 Cluster: Pyruvate kinase; n=5; Thermococcaceae|Rep: Pyruvate kinase - Thermococcus litoralis Length = 220 Score = 115 bits (276), Expect = 1e-24 Identities = 63/176 (35%), Positives = 105/176 (59%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 II TIGPAS+ ++KM++ GM+VAR+NFSHG+ E HA+TI R+ + + Sbjct: 14 IIATIGPASKQKESIKKMIKAGMSVARINFSHGTLEEHAKTIETVRDVAEKLERR----- 68 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 +AI D G ++R G ++G V L+KG+ + LTT +G+ TI V++K++ Sbjct: 69 -VAILGDLPGLKMRVGKIKGD---SVTLRKGDKVVLTTR---DIEGDETTIPVEFKDLPK 121 Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702 +V G+ I++ DG I + + V + + C + NGG+L S KG+N+P + + A++ Sbjct: 122 LVSKGDTIYLSDGYIMLRVEEVRENEVECVVVNGGILFSHKGINIPKANLPIEAIT 177 >UniRef50_Q2I6K6 Cluster: Pyruvate kinase; n=1; uncultured delta proteobacterium DeepAnt-32C6|Rep: Pyruvate kinase - uncultured delta proteobacterium DeepAnt-32C6 Length = 466 Score = 114 bits (275), Expect = 2e-24 Identities = 65/182 (35%), Positives = 98/182 (53%) Frame = +1 Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339 +R + I+CTIGPA+ + +++ GM+ AR+NFSHG+ + HA RE + + Sbjct: 1 MRRAKIVCTIGPATHTREGIRALIDAGMDCARLNFSHGTQQGHARVAALVREL----ATE 56 Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519 G P +A+ D GP+IR G G VEL +G LTT G ++Y Sbjct: 57 AGRP--IALLADLCGPKIRVGRFPEGA---VELVEGTAFTLTTR---DVAGTDKQASINY 108 Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699 + V PG+ I IDDGLI ++ + V + C +E GGML RKG+N+PG + PA+ Sbjct: 109 AALPQDVDPGDAIMIDDGLIRLVVREVEGPDIHCIVEVGGMLSERKGINVPGSALSTPAL 168 Query: 700 SE 705 ++ Sbjct: 169 TD 170 >UniRef50_Q1NTW3 Cluster: Pyruvate kinase; n=1; delta proteobacterium MLMS-1|Rep: Pyruvate kinase - delta proteobacterium MLMS-1 Length = 493 Score = 114 bits (275), Expect = 2e-24 Identities = 66/181 (36%), Positives = 102/181 (56%) Frame = +1 Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342 R + I+CTIGPA+ + + ++ E GMNVAR+N SHGS E+H I N + K Y+ Sbjct: 16 RRTKIVCTIGPATASFEAICRLAEQGMNVARLNMSHGSREWHRGVIGNIKRYNKKYAG-- 73 Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522 SLA+ LDT+G EIR+G L+ ++EL+ G+ + LTT Q + + V + Sbjct: 74 ----SLAVLLDTRGAEIRSGDLK----QDLELRVGDGLTLTTR--RQAELEPGCVEVSHD 123 Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702 V PG+ I +D G++ + V + C + G+LGSR+ +N+ G DLPA++ Sbjct: 124 GFVAEVTPGDIILVDGGMLRLKVVEVGRTDVRCQSLDEGVLGSRRHLNIRGKSADLPAIT 183 Query: 703 E 705 E Sbjct: 184 E 184 >UniRef50_A1BQT0 Cluster: Pyruvate kinase; n=2; Eukaryota|Rep: Pyruvate kinase - Monocercomonoides sp. PA203 Length = 516 Score = 114 bits (275), Expect = 2e-24 Identities = 63/186 (33%), Positives = 105/186 (56%), Gaps = 1/186 (0%) Frame = +1 Query: 151 SSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSY 330 +S+ L+ I+ T+GPA+ + +++ G+NV RMNFSHG+HE+H + + R+ + Sbjct: 32 ASFTPLTKIVATLGPATSTYETISQVVTAGVNVIRMNFSHGTHEFHEQLYKIVRKVAED- 90 Query: 331 SAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIY 510 LG +AI D +GP++RT GG ++ +K+G+ + + SP+ + G T + Sbjct: 91 ---LGK--EVAIIADLQGPKVRTNTFPGG---KITIKRGDKVSIVGSPEPGKPGVITTKF 142 Query: 511 VDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPV-D 687 NV +P + IDDGLI +I Q + + L C +E GG + KG+NLP + Sbjct: 143 TPMITHCNVGEP---VLIDDGLIRLIVQEKNPNELVCLVEQGGDVKDHKGINLPATDLGP 199 Query: 688 LPAVSE 705 LPA++E Sbjct: 200 LPALTE 205 >UniRef50_UPI0000DB6F59 Cluster: PREDICTED: similar to Pyruvate kinase CG7070-PB, isoform B; n=1; Apis mellifera|Rep: PREDICTED: similar to Pyruvate kinase CG7070-PB, isoform B - Apis mellifera Length = 538 Score = 113 bits (273), Expect = 3e-24 Identities = 60/210 (28%), Positives = 110/210 (52%), Gaps = 2/210 (0%) Frame = +1 Query: 82 EKPTVANVGSQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMN 261 E+ A ++L+H L+I+S RL+ I+ T+G + + + +M G N+ R+N Sbjct: 12 EQIKAAYQNTRLEHNINLNINSSPKLARLTRIMVTLGRRNSHPEAVVSIMMAGANIVRLN 71 Query: 262 FSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSA--EVE 435 +H + ++H T+++ R+A + + L +A++ +GPEIR G G ++ + Sbjct: 72 MAHETDKWHTATVQSVRKAGNTMYEFTSEIYPLGVAINLQGPEIRAGAFRGDKTSLGYAK 131 Query: 436 LKKGETIKLTTSPDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTL 615 LK+G+ +KL T + G A+ +V Y N+ + + G+RI ID G + + + + Sbjct: 132 LKEGKMVKLVTQDIAKRAGRANCFWVSYPNLPKICQVGDRILIDRGAVLLQVTCIHEQAI 191 Query: 616 TCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 TC I GG++ K + L V LP +SE Sbjct: 192 TCKIIKGGIVKDGKLIQLLDSLVPLPQISE 221 >UniRef50_Q8F253 Cluster: Pyruvate kinase; n=4; Leptospira|Rep: Pyruvate kinase - Leptospira interrogans Length = 478 Score = 113 bits (272), Expect = 4e-24 Identities = 63/177 (35%), Positives = 99/177 (55%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 I+CTIGPAS + + +++ GM++ARMNFSHG+H+ H R+ E+ + F Sbjct: 14 IVCTIGPASSSEETILSILKAGMDIARMNFSHGTHDSHKRVYDTLRKCEQIFG------F 67 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 L I D +GP+IRTG L+ + L K + I++ PD G+ I Y N+ Sbjct: 68 PLGIMADLQGPKIRTGKLK---LNSILLHKNQEIEIV--PDSDILGDEHKIGCTYPNLIR 122 Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 ++ ++I IDDG + + S +++ + GG+L S KG+NLPG P+ PA+SE Sbjct: 123 DIQEEDKILIDDGKLILKVISKKSNSAILKVIVGGILWSNKGINLPGTPISAPALSE 179 >UniRef50_Q40546 Cluster: Pyruvate kinase isozyme G, chloroplast precursor; n=58; Viridiplantae|Rep: Pyruvate kinase isozyme G, chloroplast precursor - Nicotiana tabacum (Common tobacco) Length = 562 Score = 113 bits (272), Expect = 4e-24 Identities = 64/195 (32%), Positives = 109/195 (55%), Gaps = 3/195 (1%) Frame = +1 Query: 130 GLDIDSKSSYI---RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETI 300 G + +S Y+ R + I+CTIGP++ + ++ K+ E GMNVAR+N SHG H H TI Sbjct: 77 GYSLGQESVYLNSPRKTKIVCTIGPSTSSREMIWKLAEAGMNVARLNMSHGDHASHQRTI 136 Query: 301 RNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDY 480 +E + K+ +AI LDTKGPE+ + G + LK+G+ + Sbjct: 137 DLVKEYNAQFEDKV-----IAIMLDTKGPEV----ISGDVPKPILLKEGQEFNFSIK--- 184 Query: 481 QEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKG 660 + DT+ V+Y + N V+ G+ + +D G++S+ +S ++D + C + +GG L SR+ Sbjct: 185 RGVSTEDTVSVNYDDFINDVEAGDILLVDGGMMSLAVKSKTSDIVKCEVIDGGELKSRRH 244 Query: 661 VNLPGIPVDLPAVSE 705 +N+ G LP+++E Sbjct: 245 LNVRGKSATLPSITE 259 >UniRef50_UPI00015BD1E0 Cluster: UPI00015BD1E0 related cluster; n=1; unknown|Rep: UPI00015BD1E0 UniRef100 entry - unknown Length = 477 Score = 113 bits (271), Expect = 5e-24 Identities = 62/177 (35%), Positives = 100/177 (56%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 I+CTIGPAS+ V L KM+E GMN+AR+NF+HGS E H + N R+A K Sbjct: 11 IVCTIGPASQEVETLTKMIENGMNIARINFAHGSFEEHETVVENIRKASKIVGK------ 64 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 + I D GP+IR G ++ +E+KKG+ + L+ EK I +++K+ + Sbjct: 65 DVTIMGDLPGPKIRIGDIK-----PMEIKKGDILILS------EKPQEGVIPINFKDFSK 113 Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 VK G+ I+++DG + ++ + V D + + G + S KGVNLP + + + A+ + Sbjct: 114 YVKVGDSIYMNDGFVELMVEKVEDDKVYAVSLSAGKISSHKGVNLPNVDLPVRAIGD 170 >UniRef50_A4MK73 Cluster: Pyruvate kinase; n=1; Petrotoga mobilis SJ95|Rep: Pyruvate kinase - Petrotoga mobilis SJ95 Length = 478 Score = 112 bits (270), Expect = 7e-24 Identities = 61/177 (34%), Positives = 104/177 (58%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 I+CTIGPA+++ +++K++ GMNVAR+N SH + H + + ++ K L PF Sbjct: 12 IVCTIGPATQDETMIKKLINAGMNVARLNTSHDTIADHEKRVNLIKKIRKD----LNIPF 67 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 AI LD +GP+IRTG E + +V L++G+ LT + GN + + ++Y+ + Sbjct: 68 --AILLDLEGPKIRTGKFE---TDQVMLEEGQKFILTIE---EIVGNKERVSINYRELPK 119 Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 VK G+ I +DDG I ++ S + + + GG + R+G+N+PGI + LP ++E Sbjct: 120 EVKKGDFILLDDGKIRLVVVSSNEKEIVTKVVTGGSITHRRGINVPGIDISLPPLTE 176 >UniRef50_Q9RR62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyruvate kinase - Deinococcus radiodurans Length = 482 Score = 112 bits (269), Expect = 9e-24 Identities = 63/181 (34%), Positives = 99/181 (54%) Frame = +1 Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342 R + I+ T+GPASR+ VL +M++ G+NV R+NFSHG E H +T++ R+ S + Sbjct: 6 RATKIVATVGPASRSTEVLGRMIDVGLNVVRLNFSHGDLEDHRQTVQMVRDLAVSKGVTI 65 Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522 G I D +GP+IR G G V L G+ +T + +GNA+ + YK Sbjct: 66 G------ILQDLQGPKIRVGRFAEG---SVTLNPGQKFVITMD---EVEGNAERVGSTYK 113 Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702 + V PG + +DDG +S+ V + + T+ GG L + KG+N+P + +PA+S Sbjct: 114 GLAGDVTPGMTLLLDDGNMSLRVDHVRGNDIQTTVLIGGTLKNNKGINVPEADLTVPALS 173 Query: 703 E 705 E Sbjct: 174 E 174 >UniRef50_Q6MAN9 Cluster: Pyruvate kinase; n=1; Candidatus Protochlamydia amoebophila UWE25|Rep: Pyruvate kinase - Protochlamydia amoebophila (strain UWE25) Length = 598 Score = 111 bits (268), Expect = 1e-23 Identities = 68/177 (38%), Positives = 99/177 (55%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 I+CTIGPA ++ + +++ GMNVAR+NFSHG+ E H TI +EA +L P Sbjct: 8 IVCTIGPACNSLEKIIELINVGMNVARLNFSHGTQEEHLRTINLLKEAR----CQLNLP- 62 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 LAI LDTKGPEIR G + G ++ L G+ +L + G+ + + NI + Sbjct: 63 -LAIMLDTKGPEIRLGKIRDG---QIFLTVGQKWRLVKK---EVLGDESQVSIFPLNILD 115 Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 + G I DDG I+ S++ + I N GM+ S KGVN+P ++LPAV+E Sbjct: 116 QLPVGTTILFDDGYIASRVIENSSEGVLVEINNSGMIRSSKGVNIPNTSLNLPAVTE 172 >UniRef50_Q56XD5 Cluster: Pyruvate kinase; n=14; Magnoliophyta|Rep: Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress) Length = 579 Score = 111 bits (267), Expect = 2e-23 Identities = 63/187 (33%), Positives = 105/187 (56%) Frame = +1 Query: 145 SKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEK 324 SK + R + I+CT+GP++ ++ K+ E GMNVARMN SHG H H + I + K Sbjct: 104 SKPTVRRKTKIVCTVGPSTNTREMIWKLAEAGMNVARMNMSHGDHASHKKVI----DLVK 159 Query: 325 SYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADT 504 Y+A+ ++AI LDTKGPE+R+G L + L G+ T + Sbjct: 160 EYNAQT-KDNTIAIMLDTKGPEVRSGDL----PQPIMLDPGQEFTFTIE---RGVSTPSC 211 Query: 505 IYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPV 684 + V+Y + N V+ G+ + +D G++S + +S + D++ C + +GG L SR+ +N+ G Sbjct: 212 VSVNYDDFVNDVEAGDMLLVDGGMMSFMVKSKTKDSVKCEVVDGGELKSRRHLNVRGKSA 271 Query: 685 DLPAVSE 705 LP+++E Sbjct: 272 TLPSITE 278 >UniRef50_Q1AXJ8 Cluster: Pyruvate kinase; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Pyruvate kinase - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 477 Score = 111 bits (266), Expect = 2e-23 Identities = 62/183 (33%), Positives = 105/183 (57%), Gaps = 1/183 (0%) Frame = +1 Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339 +R + I+ T+GPA+ + + ++ G++V R+NFSHG+H+ H + R REA +A+ Sbjct: 3 VRRTKIVATLGPATSSEESIGALVRAGVDVMRLNFSHGTHDMHLDNARTVREA----AAE 58 Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519 G ++AI D +GP+IRTG +EGG EL +G + + D+ G+A + Y Sbjct: 59 AGR--NVAIMQDLQGPKIRTGEVEGG----TELVEGSRVVIAPG-DF--VGDASRLSTSY 109 Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSAD-TLTCTIENGGMLGSRKGVNLPGIPVDLPA 696 + VKPG+R+ IDDGLI + +S+ + + C + GG + S KG+N P + + Sbjct: 110 DRLAQDVKPGHRLLIDDGLIGLRVESIKENGEIVCEVLEGGPVSSHKGLNFPDSSLSISG 169 Query: 697 VSE 705 ++E Sbjct: 170 LTE 172 >UniRef50_UPI0000D56D72 Cluster: PREDICTED: similar to CG7070-PB, isoform B; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG7070-PB, isoform B - Tribolium castaneum Length = 535 Score = 110 bits (265), Expect = 3e-23 Identities = 61/193 (31%), Positives = 101/193 (52%) Frame = +1 Query: 115 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 294 L+H+ L S+ RL+ I P ++ +E+ ++ GM VA + + + + E Sbjct: 44 LEHLARLQEKSRVRRKRLTQFSVIIPPRI-SIEHIEEFLKAGMTVALIRMDYFTVDEIEE 102 Query: 295 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSP 474 + R + K+G + +AI LD EI+TG L E+EL+KG+T K+ P Sbjct: 103 MVAMIRNVVDDFGKKIGRVYPIAIGLDVSEQEIKTGKLLKP-LKEIELEKGQTTKIVAKP 161 Query: 475 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 654 ++ + + + IYV+Y+NI +VVKPG+ + I D I + V+ D + C IE G+L Sbjct: 162 EFANRVSKEFIYVNYENIADVVKPGDSLIIGDDNIRMSAIEVARDIINCIIEKAGLLTDN 221 Query: 655 KGVNLPGIPVDLP 693 V LP +P+ LP Sbjct: 222 LSVKLPNVPITLP 234 >UniRef50_Q8YTZ8 Cluster: Pyruvate kinase; n=3; Nostocaceae|Rep: Pyruvate kinase - Anabaena sp. (strain PCC 7120) Length = 476 Score = 109 bits (263), Expect = 5e-23 Identities = 66/183 (36%), Positives = 106/183 (57%), Gaps = 1/183 (0%) Frame = +1 Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339 +R + IICT+GPA+ LE ++E GMNVAR+NFSHG++++HA+T + R+ SA Sbjct: 1 MRRTKIICTVGPATSAPERLEALVEAGMNVARLNFSHGAYDFHAQTAQYLRQ----ISAD 56 Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNA-DTIYVD 516 P +AI D GP+IR G L G + ++ G+ + QEKG++ D + + Sbjct: 57 RQKP--VAIMQDLCGPKIRLGTLPPEG---LMVEAGQEVTFV----LQEKGSSLDELPLP 107 Query: 517 YKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPA 696 + +V+PG I I+DG + +I AD + + GG+L +RKGVNLP + + + Sbjct: 108 LPTLFAMVRPGEPILINDGRVKLIVTDRDADRIRAIAKIGGLLSTRKGVNLPATRLPVSS 167 Query: 697 VSE 705 ++E Sbjct: 168 ITE 170 >UniRef50_Q44473 Cluster: Pyruvate kinase; n=4; Proteobacteria|Rep: Pyruvate kinase - Agrobacterium vitis (Rhizobium vitis) Length = 482 Score = 109 bits (263), Expect = 5e-23 Identities = 64/176 (36%), Positives = 95/176 (53%) Frame = +1 Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342 R S I+ T+GPAS + +L + G++ R+NFSHG+ HAE RN R E+ + A Sbjct: 7 RRSKIVATVGPASSSPDMLRSLFLAGVDTFRLNFSHGARADHAEVYRNIRALEQEHDA-- 64 Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522 ++A+ D +GP+IR G+L G ++L +G TI + E N I + ++ Sbjct: 65 ----AIAVLQDLQGPKIRIGVLAHG---RLDLARGSTIGFILGREGGEGMN--DIPLPHR 115 Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDL 690 I V PG + IDDG I + V L C + NGG L +RKGVN+PG +D+ Sbjct: 116 EIFEVAVPGMDLLIDDGRIKVRIMEVMDGRLVCEVLNGGALSNRKGVNVPGAVLDI 171 >UniRef50_Q1Q4I4 Cluster: Strongly similar to pyruvate kinase; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Strongly similar to pyruvate kinase - Candidatus Kuenenia stuttgartiensis Length = 472 Score = 109 bits (261), Expect = 9e-23 Identities = 66/181 (36%), Positives = 100/181 (55%) Frame = +1 Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342 R + I+CTIGPAS + A++E+++ GMNVAR+NFSHG H E I + R + S KL Sbjct: 5 RKTKIVCTIGPASNSPAMIEQLICAGMNVARLNFSHGELSQHKECISHIR----AISEKL 60 Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522 P +A+ D GP+IR G+L G V LK +T LTT GN I ++Y Sbjct: 61 MQP--VAVLQDLSGPKIRIGMLSGDA---VTLKTNDTFTLTTR---NIVGNERVISINYS 112 Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702 ++ V G+ + + DG I + + C + GG+L SRKG+N+P + + +++ Sbjct: 113 DLPMNVSIGDTLLLSDGEIEVEVIQKDDRNIHCKVIVGGVLTSRKGINIPARSLPVSSLT 172 Query: 703 E 705 E Sbjct: 173 E 173 >UniRef50_A7D456 Cluster: Pyruvate kinase; n=2; Halobacteriaceae|Rep: Pyruvate kinase - Halorubrum lacusprofundi ATCC 49239 Length = 613 Score = 108 bits (259), Expect = 2e-22 Identities = 68/207 (32%), Positives = 107/207 (51%), Gaps = 3/207 (1%) Frame = +1 Query: 91 TVANVGSQLQHMCGLDID-SKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFS 267 TV NV S CG + +KS +R + I+CTIGPAS + + + + GM+V R+N S Sbjct: 5 TVTNVHSVATQPCGFFLSCAKSGDMRNAKIVCTIGPASDSRDAIRDLADAGMSVVRLNAS 64 Query: 268 HGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKG 447 HG+ + E I R + ++ P LA+ +D KGPE+RT L+ Sbjct: 65 HGTTAHREEVIERARAVDN----EIDDP--LAVMVDLKGPEVRTAELD------------ 106 Query: 448 ETIKLTTSPD--YQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTC 621 E+I L T + + E +A V + PG+ + +DDG I + V +++ Sbjct: 107 ESISLATGSEVTFVEGDDATPERVGLTHSIAAAGPGDTVLLDDGRIECRVERVDGESVVA 166 Query: 622 TIENGGMLGSRKGVNLPGIPVDLPAVS 702 T+ +GG L SRKGVNLPG+ +D+ ++ Sbjct: 167 TVVSGGKLSSRKGVNLPGVAIDVDLIT 193 >UniRef50_A6LH43 Cluster: Pyruvate kinase; n=2; Parabacteroides|Rep: Pyruvate kinase - Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / NCTC11152) Length = 485 Score = 107 bits (256), Expect = 3e-22 Identities = 65/177 (36%), Positives = 96/177 (54%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 I+ T+ +VA +E + + GMNV R+N +H E + N R + S ++G Sbjct: 7 IVATVSDQRCDVAFVEALYKAGMNVVRLNTAHMMEEGLTRVVNNVR----TVSDRIG--- 59 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 I +DTKGPE+RT + K GE +K+ +PD QE + D I V YKN N Sbjct: 60 ---ILMDTKGPEVRTTTTVN--KEPIPFKTGEIVKVIGNPD-QETSH-DCICVSYKNFVN 112 Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 + G+ I IDDG + + S D L C I+N LGSRK VN+PG+ ++LP+++E Sbjct: 113 DLAIGSDILIDDGDLEMKVTGKSGDCLLCEIQNDATLGSRKSVNVPGVRINLPSLTE 169 >UniRef50_A0QNT2 Cluster: Pyruvate kinase; n=1; Mycobacterium smegmatis str. MC2 155|Rep: Pyruvate kinase - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 477 Score = 107 bits (256), Expect = 3e-22 Identities = 57/181 (31%), Positives = 96/181 (53%) Frame = +1 Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342 R + I+CT+GPA+ +VL ++++ GM+VAR+NFSH +H H+ RE + Sbjct: 4 RRAKIVCTLGPATATSSVLTELVDAGMDVARLNFSHSTHAEHSALYGMVREIAAQRGRVV 63 Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522 G + D +GP+IR G G V GE + +TT G+ D + Y Sbjct: 64 G------VLADLQGPKIRLGCFADG---PVVWATGEHVTITTEDC---PGDHDRVSTTYA 111 Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702 ++ V+ G+R+ +DDG + + +V + C + +GG + KG++LP IPV +P +S Sbjct: 112 GLSQDVRAGDRLLVDDGRVDLRVVAVDGPDIRCEVVDGGPVSDHKGISLPNIPVSVPPLS 171 Query: 703 E 705 + Sbjct: 172 D 172 >UniRef50_P94685 Cluster: Pyruvate kinase; n=8; Chlamydiaceae|Rep: Pyruvate kinase - Chlamydia trachomatis Length = 485 Score = 106 bits (254), Expect = 6e-22 Identities = 62/177 (35%), Positives = 95/177 (53%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 IICTIGPA+ +LEK+++ GMNVAR+NFSHG+HE H TI +E + Sbjct: 7 IICTIGPATNTPEMLEKLLDAGMNVARLNFSHGTHESHGRTIAILKELREKRQV------ 60 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 LAI LDTKGPEIR G +E + ++++ G+ + L + K + T+Y + Sbjct: 61 PLAIMLDTKGPEIRLGQVE----SPIKVQPGDRLTLVSKEILGSKESGVTLYPSC--VFP 114 Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 V+ + IDDG I + + + +N G + S K +++ I V LP ++E Sbjct: 115 YVRERAPVLIDDGYIQAVVVNAQEHMVEIEFQNSGEIKSNKSLSIKDIDVALPFMTE 171 >UniRef50_Q82XE9 Cluster: Pyruvate kinase family; n=130; Proteobacteria|Rep: Pyruvate kinase family - Nitrosomonas europaea Length = 496 Score = 105 bits (252), Expect = 1e-21 Identities = 59/181 (32%), Positives = 100/181 (55%) Frame = +1 Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339 +R + I+ T+GPAS N VL +M+E G++V R+NFSHG+ + H ++ E +S + Sbjct: 2 MRRTKIVATLGPASSNAEVLGRMLEAGVDVIRINFSHGTKDEHIASV----ELVRSLARS 57 Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519 LG ++ + D +GP+IR G E G ++ LK G+ L + GN + + +DY Sbjct: 58 LGR--TVGVLADLQGPKIRIGKFEQG---KIRLKTGDEFILDAE---CQLGNQERVGLDY 109 Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699 + + N V+ G + +DDG I + V + C + GG+L + KG+N G + PA+ Sbjct: 110 RELPNDVEAGATLLLDDGRIVLTVAKVRESEIFCEVLQGGILSNNKGINRKGGGLSAPAL 169 Query: 700 S 702 + Sbjct: 170 T 170 >UniRef50_Q2JLA2 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep: Pyruvate kinase - Synechococcus sp. (strain JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone B-Prime) Length = 619 Score = 105 bits (252), Expect = 1e-21 Identities = 67/182 (36%), Positives = 95/182 (52%), Gaps = 2/182 (1%) Frame = +1 Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342 R + I+ TIGPAS N A+L +M+ G R+NFSHG HE H +IR R+ + L Sbjct: 8 RRTKIVATIGPASSNPAILREMILQGATTLRLNFSHGDHELHRRSIRLIRQT----AMDL 63 Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522 G +AI D +GP+IR G G + LK G+ LT+ P G+ + +V Y Sbjct: 64 G--IQVAILQDLQGPKIRLGKFAEG---SITLKAGDPFVLTSKP---VLGSQERSWVTYD 115 Query: 523 NITNVVKPGNRIFIDDGLISIICQSV--SADTLTCTIENGGMLGSRKGVNLPGIPVDLPA 696 + V G I IDDG + + ++V A L C GG L + KGVN PG+ + + A Sbjct: 116 KLAQEVPEGATILIDDGRVEMRVEAVDPEAGELFCRTIVGGTLSNNKGVNFPGVRLSIRA 175 Query: 697 VS 702 V+ Sbjct: 176 VT 177 >UniRef50_A6Q7D7 Cluster: Pyruvate kinase; n=19; cellular organisms|Rep: Pyruvate kinase - Sulfurovum sp. (strain NBC37-1) Length = 488 Score = 105 bits (251), Expect = 1e-21 Identities = 61/179 (34%), Positives = 98/179 (54%), Gaps = 2/179 (1%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 II TIGPA+ + ++ +M G+N+ R+NFSHG+HEYH+E + R+A + G Sbjct: 7 IIATIGPATDSYEKIKALMCAGVNLFRLNFSHGTHEYHSEVLGRIRKAIEETGLITG--- 63 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSP--DYQEKGNADTIYVDYKNI 528 I D GP+IR G+LE + LK G+ ++ Y+ K + ++ +I Sbjct: 64 ---ILQDISGPKIRVGMLE----EDFILKSGDILEFVKEEIVGYKVKEGVYRLCINEPDI 116 Query: 529 TNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 + ++ G I++ DG+I + + SAD + IEN GML SRKGVN P + + ++E Sbjct: 117 LDQLEVGESIYMYDGIIRAVVKEKSADMVKVEIENNGMLSSRKGVNFPNTHLGINVLTE 175 >UniRef50_P73534 Cluster: Pyruvate kinase 2; n=37; Bacteria|Rep: Pyruvate kinase 2 - Synechocystis sp. (strain PCC 6803) Length = 591 Score = 105 bits (251), Expect = 1e-21 Identities = 64/184 (34%), Positives = 102/184 (55%), Gaps = 3/184 (1%) Frame = +1 Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342 R + I+ TIGPA+++ VL ++++ G R+NFSHG H YH ++IR R+ + +L Sbjct: 8 RRTKIVATIGPATQSKEVLRQLIQAGATTFRLNFSHGDHAYHQQSIRLIRQ----IAFEL 63 Query: 343 GSPFSLAIALDTKGPEIRTG-LLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519 P + I D +GP+IR G L GS V+LK G+ LT+ P + + Y Sbjct: 64 NQP--VGILQDLQGPKIRVGKFLNDAGS--VQLKNGDPYTLTSRP---VECTETISSISY 116 Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVS--ADTLTCTIENGGMLGSRKGVNLPGIPVDLP 693 + + + V G RI +DDG + ++ + V A L C + GG L S KGVN PG+ + + Sbjct: 117 EYLADEVPSGARILLDDGKLEMLVEEVDTVARDLHCRVIVGGTLSSNKGVNFPGVCLSVK 176 Query: 694 AVSE 705 A+++ Sbjct: 177 AMTD 180 >UniRef50_A4APL1 Cluster: Pyruvate kinase; n=15; Bacteroidetes|Rep: Pyruvate kinase - Flavobacteriales bacterium HTCC2170 Length = 480 Score = 104 bits (249), Expect = 2e-21 Identities = 59/183 (32%), Positives = 101/183 (55%), Gaps = 1/183 (0%) Frame = +1 Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339 I+ + I+ T+GPA+ V+ M++ G++V R+NFSH +E ++ RE + + Sbjct: 4 IKKTKIVATLGPATSKKEVIIDMIKAGVDVFRINFSHADYEDVTARVKMIREVNEEIDS- 62 Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519 ++AI D +GP++R G++ G EV + G+ I T ++ GN++ +Y++Y Sbjct: 63 -----NIAILGDLQGPKLRVGVMSG----EVVVTPGDEIDFVTGEPFE--GNSERVYMNY 111 Query: 520 KNITNVVKPGNRIFIDDG-LISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPA 696 V PG RI +DDG L+ + + D + + GG L S+KGVNLP + LPA Sbjct: 112 AAFPKDVNPGERILLDDGKLMFEVVSTNKKDKVRAKVIQGGPLKSKKGVNLPNTNISLPA 171 Query: 697 VSE 705 ++E Sbjct: 172 LTE 174 >UniRef50_Q8G5M1 Cluster: Pyruvate kinase; n=23; Actinobacteridae|Rep: Pyruvate kinase - Bifidobacterium longum Length = 509 Score = 103 bits (248), Expect = 3e-21 Identities = 59/189 (31%), Positives = 104/189 (55%), Gaps = 2/189 (1%) Frame = +1 Query: 145 SKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEK 324 ++ +++R + I+ TIGP++ + L K++E GM+VAR+N SHG+ E H + N R+A + Sbjct: 25 NRQAFMRKAKIVDTIGPSTEDYDNLLKLVEAGMDVARLNRSHGTPEDHLKVYNNVRKASE 84 Query: 325 SYSAKLGSPFSLAIALDTKGPEIRTGLLE--GGGSAEVELKKGETIKLTTSPDYQEKGNA 498 + ++A +D +GP+IR G + G +V+L+ G+ +TT +G+ Sbjct: 85 ATGR------NVAALVDLQGPKIRCGWFKKNADGEDKVQLQLGQEFVITTD---DVEGDE 135 Query: 499 DTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGI 678 +K + PG+ I IDDG + + V + + + G + S KG+NLPG+ Sbjct: 136 HITSTTFKGLPGDCHPGDPILIDDGKVRLEVTKVEGNNVYTKVVVAGPVSSHKGINLPGV 195 Query: 679 PVDLPAVSE 705 V LPA++E Sbjct: 196 AVSLPALTE 204 >UniRef50_Q8SQP0 Cluster: Pyruvate kinase; n=1; Encephalitozoon cuniculi|Rep: Pyruvate kinase - Encephalitozoon cuniculi Length = 519 Score = 103 bits (248), Expect = 3e-21 Identities = 62/176 (35%), Positives = 101/176 (57%), Gaps = 3/176 (1%) Frame = +1 Query: 166 LSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLG 345 L+ I+CTIGP + + ++++++ GM++AR+NFSHGS E H E IRN R+ ++ G Sbjct: 96 LTKIVCTIGPRTSSREKIKELIDAGMSIARLNFSHGSREAHLEVIRNIRD------SRSG 149 Query: 346 SPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIK---LTTSPDYQEKGNADTIYVD 516 + ++IALDT+GPE+R L +++++ GE ++ L++ D G VD Sbjct: 150 AGRHVSIALDTRGPEVR---LRTPEMKDIKVEGGEVLRFSLLSSEKDIWIPG------VD 200 Query: 517 YKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPV 684 K++ NR+FIDDG I + +V D C + N GM+ S K +N PG + Sbjct: 201 LKSL----GVDNRVFIDDGAIELRVVNVEEDGFECEVLNSGMIKSNKSMNFPGTDI 252 >UniRef50_A6FYT4 Cluster: Pyruvate kinase; n=1; Plesiocystis pacifica SIR-1|Rep: Pyruvate kinase - Plesiocystis pacifica SIR-1 Length = 485 Score = 103 bits (247), Expect = 4e-21 Identities = 61/182 (33%), Positives = 100/182 (54%) Frame = +1 Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339 +R + I+ T+GPAS + ++ +M+ G++ R+NFSHGSHE HA+ RE + S + Sbjct: 6 LRRAKILGTLGPASNSDEMIGALMDAGLDAVRLNFSHGSHEDHAQVYGKVRE-QSSIRRR 64 Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519 +A+ D +GP+IR G + G + L+ GET+ T P + TI DY Sbjct: 65 -----PVAVLGDLQGPKIRVGKIPDPG---MTLETGETLVFLTDPTAEISQGRVTI--DY 114 Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699 + K G R+ +DDG + ++A + + NGG+L +RKGVNLP + LP++ Sbjct: 115 PTLDEEAKVGERVLMDDGELEARITEINAGEVHAEMLNGGVLKARKGVNLPDSDLLLPSL 174 Query: 700 SE 705 ++ Sbjct: 175 TD 176 >UniRef50_Q7UF82 Cluster: Pyruvate kinase; n=1; Pirellula sp.|Rep: Pyruvate kinase - Rhodopirellula baltica Length = 476 Score = 102 bits (244), Expect = 1e-20 Identities = 60/185 (32%), Positives = 97/185 (52%), Gaps = 4/185 (2%) Frame = +1 Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342 R + II TIGPA+ + L ++E G++V R+N +HG+ E+ E + R+ K S + Sbjct: 5 RHTKIIATIGPATESPEKLAALIEAGVDVMRLNMAHGTPEWVGEIVARIRKVSKDISRHV 64 Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSP----DYQEKGNADTIY 510 A+ +D KGPEIRTG +E +ELK G+ + L T E + Sbjct: 65 ------AVMMDVKGPEIRTGAVEDA----IELKAGDELVLFTEDCADQSAVESDGTPRVS 114 Query: 511 VDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDL 690 V+Y + + + I +D GL+ A T+ C + G+L SR+ +NLPG+ V+L Sbjct: 115 VNYLGLPGAIDLDSTILVDSGLLHWHVLKKDATTVRCRVITPGVLESRRHINLPGVQVNL 174 Query: 691 PAVSE 705 PA+++ Sbjct: 175 PAITD 179 >UniRef50_A0L7K0 Cluster: Pyruvate kinase; n=1; Magnetococcus sp. MC-1|Rep: Pyruvate kinase - Magnetococcus sp. (strain MC-1) Length = 569 Score = 101 bits (243), Expect = 1e-20 Identities = 61/181 (33%), Positives = 93/181 (51%), Gaps = 1/181 (0%) Frame = +1 Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342 R + I+ T+GPA +V + +++E G++VAR+N SHG H+ H E I N REA S AK Sbjct: 3 RRAKIVATLGPACSSVEQITRLIEAGLDVARLNMSHGDHKAHLELIHNVREA--SRIAKR 60 Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIY-VDY 519 +A+ D +GP+IR G L+ + L+KG+ + + K D I Y Sbjct: 61 ----EVALLCDLQGPKIRVGHLD----EPLRLEKGQQWAIIPEGSHPPKLKCDGIIPCTY 112 Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699 + PG RI DDG + L IE+GG+L S KG+N+P + P++ Sbjct: 113 AGLAKDAVPGCRILFDDGYLQARAIGTEEGALLVNIEHGGLLKSHKGINMPDASISAPSL 172 Query: 700 S 702 + Sbjct: 173 T 173 >UniRef50_A7CAK5 Cluster: Pyruvate kinase; n=3; Ralstonia pickettii|Rep: Pyruvate kinase - Ralstonia pickettii 12D Length = 507 Score = 100 bits (240), Expect = 3e-20 Identities = 57/188 (30%), Positives = 94/188 (50%) Frame = +1 Query: 142 DSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAE 321 ++K R + I+ T+GPAS + + + + G +V R+NFSHGSHE H + R E Sbjct: 13 NTKMRRFRNTKILATLGPASSDKDTIRALFDAGADVFRLNFSHGSHEDHRKRYDTVRAVE 72 Query: 322 KSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNAD 501 A+ G P + I D +GP++R G G V LK G+ L P G+ Sbjct: 73 ----AETGRP--IGILADMQGPKLRIGTFADG---RVVLKNGDRFVLDRDP---TPGDVT 120 Query: 502 TIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIP 681 +++ + + PG + +DDG I + ++ + + +GG L RKGVN+P Sbjct: 121 RVHLPHPELYAATAPGQSLLLDDGKIRLAVEAADPTAIVTRVVDGGPLSDRKGVNVPDAV 180 Query: 682 VDLPAVSE 705 + +PA++E Sbjct: 181 IPIPALTE 188 >UniRef50_Q6YQT6 Cluster: Pyruvate kinase; n=6; Candidatus Phytoplasma|Rep: Pyruvate kinase - Onion yellows phytoplasma Length = 446 Score = 100 bits (239), Expect = 4e-20 Identities = 61/178 (34%), Positives = 101/178 (56%), Gaps = 2/178 (1%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 IICT+GPAS + +L+ +++TG+NVAR NFSH +E ++ K+ S KL Sbjct: 6 IICTLGPASYDKNILQALIQTGLNVARFNFSHAQYEQTKLLMKTI----KTISDKLDK-- 59 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 + + LDTKGPEIRT +G V ++K +K++ + + GNA V Y N+ N Sbjct: 60 NTGLMLDTKGPEIRTHEFDG----VVTIQKDSEVKISMT---EVLGNAKLFSVSYSNLYN 112 Query: 535 VVKPGNRIFIDDGLIS--IICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702 +K G+ + IDDG +S ++ + + L +N + SR+GVN+P + +++ +S Sbjct: 113 ELKVGDMVNIDDGYLSLEVVGKDEAKQQLVTKAKNTHSIKSRRGVNVPKVNLEMDFIS 170 >UniRef50_A6DH47 Cluster: Pyruvate kinase; n=1; Lentisphaera araneosa HTCC2155|Rep: Pyruvate kinase - Lentisphaera araneosa HTCC2155 Length = 485 Score = 100 bits (239), Expect = 4e-20 Identities = 59/178 (33%), Positives = 99/178 (55%), Gaps = 1/178 (0%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 I+ T+GP ++ L++++E G++V R+NFSHGSHE HAE I+ A +G Sbjct: 9 IVSTLGPTTKGR--LKELIEEGVDVFRLNFSHGSHEEHAERIQEVISAATELKRTVG--- 63 Query: 355 SLAIALDTKGPEIRTG-LLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNIT 531 I D +GP+IR G ++EGG ++L+ G+ + +TT E T++ + + Sbjct: 64 ---ILGDLQGPKIRCGKIIEGG----IQLEAGQELVITTDEILGEGSRISTVF---QALP 113 Query: 532 NVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 VK G+ I +DDGL+ + + + + + C + G L S KG+NLP + PA++E Sbjct: 114 REVKVGDPILMDDGLLEAVVERIEGNEIFCKMLVAGKLTSNKGINLPETDIQSPALTE 171 >UniRef50_Q6AII5 Cluster: Pyruvate kinase; n=1; Desulfotalea psychrophila|Rep: Pyruvate kinase - Desulfotalea psychrophila Length = 581 Score = 99.5 bits (237), Expect = 7e-20 Identities = 61/177 (34%), Positives = 97/177 (54%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 II T+GP S++V + +++ GMNVAR+N SHG E + I N +EA K + Sbjct: 6 IIATLGPQSQSVEEIYSLIQAGMNVARINLSHGDAESYKHLISNVKEARKL------AEK 59 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 AI LD +GPEIR +E ++ L GE + +T + E + I +Y + Sbjct: 60 DTAILLDNRGPEIRVSEME----EDIHLVDGEELVIT---NRAETVSPSRITTNYPQLAG 112 Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 V+ G+RI +DDG +++ ++ + + + GG+L SRK V LP V+LP++SE Sbjct: 113 DVQVGSRILLDDGKLALEVLAIEDEEVITKVIAGGILSSRKRVALPDNEVNLPSLSE 169 >UniRef50_O05118 Cluster: Pyruvate kinase; n=44; Proteobacteria|Rep: Pyruvate kinase - Methylobacterium extorquens (Protomonas extorquens) Length = 483 Score = 97.9 bits (233), Expect = 2e-19 Identities = 57/181 (31%), Positives = 95/181 (52%) Frame = +1 Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342 R + I+ T+GPAS ++EK+ G +V R+N SH + E E I R E+ + Sbjct: 10 RRTKIVATLGPASDTPEMIEKLFHAGADVFRINMSHLAREKLPERIEVIRTIEREGKRPI 69 Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522 G I +D +GP++R G G + L+ G+T L + P G+ D +++ + Sbjct: 70 G------ILVDLQGPKLRLGTFVGDAAV---LENGQTFVLDSDPT---PGDTDRVFLPHP 117 Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702 I + ++P + I IDDG + +I VS +E GG + +RKGV+LP + +PA++ Sbjct: 118 EILSALEPSHGILIDDGKLRLIVTEVSEGRAVTRVEVGGRISNRKGVSLPHTALPVPAMT 177 Query: 703 E 705 E Sbjct: 178 E 178 >UniRef50_Q04668 Cluster: Pyruvate kinase; n=2; Leishmania braziliensis|Rep: Pyruvate kinase - Leishmania braziliensis Length = 91 Score = 97.5 bits (232), Expect = 3e-19 Identities = 54/99 (54%), Positives = 72/99 (72%), Gaps = 1/99 (1%) Frame = +1 Query: 109 SQLQHMCGLDIDSKSSYIRLSG-IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEY 285 SQL H L I +R +G I+CTIGP++++V L+ ++++GM+VARMNFSHGSHEY Sbjct: 2 SQLAHNLTLSIFEP---LRTTGTIVCTIGPSTQSVEALKGLIKSGMSVARMNFSHGSHEY 58 Query: 286 HAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTG 402 H TI N R+A +A+LG ++AIALDTKGPEIRTG Sbjct: 59 HQTTINNVRQA----AAELG--VNIAIALDTKGPEIRTG 91 >UniRef50_A6C474 Cluster: Pyruvate kinase; n=1; Planctomyces maris DSM 8797|Rep: Pyruvate kinase - Planctomyces maris DSM 8797 Length = 489 Score = 96.3 bits (229), Expect = 6e-19 Identities = 54/179 (30%), Positives = 101/179 (56%), Gaps = 2/179 (1%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 II T+GPAS + +L+K++ G+++ R+NF+HG HE+ +E ++N E SA++ P Sbjct: 17 IIATVGPASDSREMLQKLIIAGVDLFRLNFAHGKHEWLSEIVKNIHE----ISAEMEKP- 71 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 + I D GP+IR G+L G E+ ++ + D N + Y+++ Sbjct: 72 -IGILGDLSGPKIRLGVLPGD---EITCRQDMRFRFIQGLD---SDNPQELTCTYESLIG 124 Query: 535 VVKPGNRIFIDDGLISIICQSVSADT--LTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 ++ G+ + + DG++++ SAD + C +E G++ S++GVNLPG+ + P ++E Sbjct: 125 DLRVGDPVLLADGMVAMRVVEKSADDEFVECVVEREGIIRSKQGVNLPGVQLSTPCLTE 183 >UniRef50_A6Q5W9 Cluster: Pyruvate kinase; n=2; Epsilonproteobacteria|Rep: Pyruvate kinase - Nitratiruptor sp. (strain SB155-2) Length = 458 Score = 95.9 bits (228), Expect = 9e-19 Identities = 62/179 (34%), Positives = 99/179 (55%) Frame = +1 Query: 166 LSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLG 345 ++ I+ TIGP+S + ++K++ G+NV R+NFSH H+ H +I+ RE K KLG Sbjct: 1 MTKIVATIGPSS--IEKIDKLILAGVNVFRLNFSHADHKTHKASIKKIRETAK----KLG 54 Query: 346 SPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKN 525 + AI D GP+IR G ++G +EL KG+ I+L + K D + + Y Sbjct: 55 T--KTAILQDISGPKIRIGEVDG----ILELSKGDKIRLVKT---HPKSKYD-LTLSYPQ 104 Query: 526 ITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702 I + ++ G +F DG I +D++T ++N G+L SRKGVN P + L A++ Sbjct: 105 IIDDLEVGEYVFFADGTIRTKVIEKDSDSVTLLVKNPGVLSSRKGVNFPHSNLRLSAIT 163 >UniRef50_A1WED1 Cluster: Pyruvate kinase; n=1; Verminephrobacter eiseniae EF01-2|Rep: Pyruvate kinase - Verminephrobacter eiseniae (strain EF01-2) Length = 496 Score = 95.9 bits (228), Expect = 9e-19 Identities = 59/171 (34%), Positives = 90/171 (52%) Frame = +1 Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342 R + I+ T+GPAS A+LE M+ G+NV R+NFSHG + H + R A + Sbjct: 23 RATKIVATLGPASSEPALLEAMIRAGVNVVRLNFSHGKAQDHIDRAACVRAAAQR----- 77 Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522 + +AI D +GP+IR G G V L G L S E G+ D + +DYK Sbjct: 78 -AGHEVAIMADLQGPKIRVGKFAEG---RVLLAPGAPFVLDAS--RTEPGDIDGVGLDYK 131 Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPG 675 + + VK G+ + ++DGLI + +V + + T++ GG L + KG+N G Sbjct: 132 ELPHDVKGGDLLLLNDGLIVLSVDAVRGEQVHTTVKIGGELSNNKGINKKG 182 >UniRef50_Q6KHW9 Cluster: Pyruvate kinase; n=3; Mycoplasma|Rep: Pyruvate kinase - Mycoplasma mobile Length = 483 Score = 95.5 bits (227), Expect = 1e-18 Identities = 65/179 (36%), Positives = 94/179 (52%) Frame = +1 Query: 169 SGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGS 348 S +I TIGP+S+N +L++MM GM R NFSHG HAE + N K + +L Sbjct: 17 SKMIATIGPSSQNKEILKQMMLKGMTTVRANFSHGD---HAEQL-NKFVLAKEVAKELNL 72 Query: 349 PFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNI 528 P SL LDTKGPEIR G ++ GS ++E+ K T+ LT Y+ T + + Sbjct: 73 PMSL--MLDTKGPEIRVGKMK-DGSQKIEVGKIITV-LTDEVSYKTFEGIPTKFTVSHRM 128 Query: 529 TNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 VK G+ I DDG ++ I V + + N +L S K +N+PG + L +S+ Sbjct: 129 DKDVKVGSYILFDDGKLTTIVTGVKSGIVEVKTINSHVLKSNKRINIPGAQLSLEFLSK 187 >UniRef50_A0L5K6 Cluster: Pyruvate kinase; n=5; Proteobacteria|Rep: Pyruvate kinase - Magnetococcus sp. (strain MC-1) Length = 483 Score = 95.5 bits (227), Expect = 1e-18 Identities = 56/182 (30%), Positives = 100/182 (54%) Frame = +1 Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339 IR + II T+GP + + ++ + TG++ R+NFSHGSHE H R E+ + Sbjct: 4 IRRTKIIATLGPNASSRDFIKHLALTGVDTFRLNFSHGSHEDHRRRHGWIRSVEE----E 59 Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519 LG P L I +D +GP++R G E ++EVEL +G+ L + G+ + + + + Sbjct: 60 LGRP--LGIMMDLQGPKLRIGTFE---NSEVELVRGQKFALYKE---ERTGDINGVTLPH 111 Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699 + V++PG + ++DG I++ V + C + GG+L RKG+N+P + + A+ Sbjct: 112 NELFQVMRPGLELLLNDGRINLRVMEVEDFGVCCEVRVGGILSDRKGLNVPAAMLPVKAL 171 Query: 700 SE 705 ++ Sbjct: 172 TD 173 >UniRef50_Q64MR8 Cluster: Pyruvate kinase; n=6; Bacteroides|Rep: Pyruvate kinase - Bacteroides fragilis Length = 485 Score = 94.7 bits (225), Expect = 2e-18 Identities = 56/182 (30%), Positives = 93/182 (51%) Frame = +1 Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339 ++ + I+ +I +V ++++ + GMNV RMN +H S E I N R Sbjct: 3 LKQTKIVASISDRRCDVDFIKELFDAGMNVVRMNTAHASREGFEALIANVRAVSNR---- 58 Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519 +AI +DTKGPE+RT + + + GE +K+ PD + + I V Y Sbjct: 59 ------IAILMDTKGPEVRTT----ANADPILYQIGEKVKIVGDPDRET--TRECIAVSY 106 Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699 N + + G I IDDG + + + + L C ++N LGSRK VN+PG+ ++LP++ Sbjct: 107 PNFVHDLNVGGTILIDDGDLELRVIDKTTEYLLCEVQNEATLGSRKSVNVPGVRINLPSL 166 Query: 700 SE 705 +E Sbjct: 167 TE 168 >UniRef50_Q63P20 Cluster: Pyruvate kinase; n=74; Proteobacteria|Rep: Pyruvate kinase - Burkholderia pseudomallei (Pseudomonas pseudomallei) Length = 484 Score = 93.1 bits (221), Expect = 6e-18 Identities = 53/180 (29%), Positives = 95/180 (52%) Frame = +1 Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342 R + I+ T+GP+S +E + G +V R+NFSHG+H HA +R+ A ++ A++ Sbjct: 13 RSTKIVATLGPSSSTETAIEALARAGADVFRLNFSHGTHADHA--LRHA--AVRAIEARI 68 Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522 G P + + LD +GP++R G G ++ KG P G+A + + + Sbjct: 69 GHP--IGVLLDLQGPKLRVGQFASG---RAQIAKGRPFVFDRDP---APGDARRVSLPHP 120 Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702 I + +PG+ + +DDG + +VS+ + T G++ RKGV++P + +PA+S Sbjct: 121 EIFDAARPGHLLLVDDGKLRFRVDAVSSARIETTALLDGIVSDRKGVSVPDATLAIPALS 180 >UniRef50_Q2TSX0 Cluster: Pyruvate kinase; n=2; cellular organisms|Rep: Pyruvate kinase - Phaeodactylum tricornutum Length = 665 Score = 92.3 bits (219), Expect = 1e-17 Identities = 53/165 (32%), Positives = 85/165 (51%) Frame = +1 Query: 178 ICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 357 + T+GPAS N ++EK+ G +V R+NFSHGS E E + RE E+ YS +G Sbjct: 158 VVTLGPASSNKEMIEKLFLAGADVFRLNFSHGSQEQKKELLIMIREVEEKYSHPIG---- 213 Query: 358 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITNV 537 I D +GP++R G +EL G++ +L KG+ + + + I Sbjct: 214 --ILGDLQGPKLRVGEFSKPEGEFLEL--GQSFRLDLD---NAKGDNKRVQLPHPEIIKA 266 Query: 538 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLP 672 + G+ + +DDG + ++ + D L C ++ GM+ RKGVN P Sbjct: 267 SELGHALLVDDGKVKLVVTAKGDDYLECRVDVAGMIKDRKGVNTP 311 >UniRef50_Q9WY51 Cluster: Pyruvate kinase; n=3; Thermotogaceae|Rep: Pyruvate kinase - Thermotoga maritima Length = 466 Score = 91.9 bits (218), Expect = 1e-17 Identities = 56/182 (30%), Positives = 98/182 (53%) Frame = +1 Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339 +R + I+CT+GP + + ++EKM++ G+NV R+N SHG + I ++ + K Sbjct: 1 MRSTKIVCTVGPRTDSYEMIEKMIDLGVNVFRINTSHGDWNEQEQKILKIKDLRE----K 56 Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519 P +AI +D GP+IRTG LE VELK+G+ LTT + GN + V+ Sbjct: 57 KKKP--VAILIDLAGPKIRTGYLE---KEFVELKEGQIFTLTTK---EILGNEHIVSVNL 108 Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699 ++ VK G+ I + DG I + + + ++ GG + R+GVN+P + + ++ Sbjct: 109 SSLPKDVKKGDTILLSDGEIVLEVIETTDTEVKTVVKVGGKITHRRGVNVPTADLSVESI 168 Query: 700 SE 705 ++ Sbjct: 169 TD 170 >UniRef50_Q9YEU2 Cluster: Pyruvate kinase; n=1; Aeropyrum pernix|Rep: Pyruvate kinase - Aeropyrum pernix Length = 458 Score = 91.5 bits (217), Expect = 2e-17 Identities = 56/176 (31%), Positives = 95/176 (53%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 I+ T+GP+S + ++L +M+ G++VAR+N SHG E + + R AE++ ++G Sbjct: 7 IVATVGPSSSSASILAQMLSLGVDVARINASHGGVEQWNSMLESLRRAEEAVGKRVG--- 63 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 +A+D +GP +RT G S V+L+KG+ + L + E + VD + Sbjct: 64 ---VAVDLEGPRVRT-----GNSEPVKLEKGDLVTL----GFME----GDVPVDARQFFE 107 Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702 + G+ + +DDG I + +SV + + GG+LG RKGV + G DLP +S Sbjct: 108 TIDEGDIVLLDDGKIILQVESVEGFRVKARVLEGGVLGPRKGVVVRGKEPDLPPLS 163 >UniRef50_O51323 Cluster: Pyruvate kinase; n=5; cellular organisms|Rep: Pyruvate kinase - Borrelia burgdorferi (Lyme disease spirochete) Length = 477 Score = 89.4 bits (212), Expect = 7e-17 Identities = 55/181 (30%), Positives = 93/181 (51%) Frame = +1 Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342 +L+ I+ TI ++ + + G+NV R+N +H SHE + I N R+ Sbjct: 4 KLTKIVATISDLRCEPEHIKDLHDAGVNVIRLNTAHQSHEDTIKVIDNVRKISNK----- 58 Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522 +A+ +DTKGPE+RT +E + +K G+ + ++TSP E N T +Y Sbjct: 59 -----IALMIDTKGPEVRTANIEN----PIIVKTGDKVIISTSP-INEPNNFQT---NYD 105 Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702 V G+++ IDDG + + + D L C I+N G + ++K +N PGI + L +V+ Sbjct: 106 GFVKEVPQGSKVLIDDGELEMTVVAKLPDRLICEIKNDGQIKNKKSINTPGISLKLQSVT 165 Query: 703 E 705 E Sbjct: 166 E 166 >UniRef50_Q7QVW2 Cluster: Pyruvate kinase; n=1; Giardia lamblia ATCC 50803|Rep: Pyruvate kinase - Giardia lamblia ATCC 50803 Length = 553 Score = 89.0 bits (211), Expect = 1e-16 Identities = 52/180 (28%), Positives = 93/180 (51%), Gaps = 2/180 (1%) Frame = +1 Query: 139 IDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREA 318 +D + I CT+GP+S NV V+ M+ G ++ R+NFSHG+ + H + ++A Sbjct: 30 VDKNHPHFNRVKICCTLGPSSFNVEVIAGMIRAGADIIRINFSHGNTDDHTQIFHKVQQA 89 Query: 319 EKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNA 498 + K ++AI D +GP++R + +ELK+G+ L + G+ Sbjct: 90 -MQLTGK-----TVAIMGDIQGPKLRIAGFSNPDNC-IELKEGQEFTLDHN---NVNGDE 139 Query: 499 DTIYVDYKNITNVVKPGNRIFIDDGLISIICQSV--SADTLTCTIENGGMLGSRKGVNLP 672 +Y+ +K V +P + I ++DG I ++ SV A + ++ GG LG+RKG+ +P Sbjct: 140 SRVYLPHKEFFAVCEPNDDIILNDGYIRLVATSVDRQAMRIVTRVKTGGKLGARKGITIP 199 >UniRef50_UPI0000DA20CA Cluster: PREDICTED: similar to Pyruvate kinase isozyme M2; n=4; Rattus norvegicus|Rep: PREDICTED: similar to Pyruvate kinase isozyme M2 - Rattus norvegicus Length = 123 Score = 88.6 bits (210), Expect = 1e-16 Identities = 44/89 (49%), Positives = 62/89 (69%) Frame = +1 Query: 115 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 294 L+HMC L+IDS +GIICTIG ++V +L+ M+ +GMNVA +NFSHG+HEYHAE Sbjct: 27 LEHMCCLEIDSAPIMAHNTGIICTIG---QSVEMLKGMIMSGMNVAHLNFSHGTHEYHAE 83 Query: 295 TIRNCREAEKSYSAKLGSPFSLAIALDTK 381 TI+N +S+++ S+ +ALDTK Sbjct: 84 TIKNVCATTESFASDPILYLSIVVALDTK 112 >UniRef50_Q5C2V0 Cluster: Pyruvate kinase; n=1; Schistosoma japonicum|Rep: Pyruvate kinase - Schistosoma japonicum (Blood fluke) Length = 168 Score = 88.6 bits (210), Expect = 1e-16 Identities = 44/136 (32%), Positives = 80/136 (58%) Frame = +1 Query: 109 SQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYH 288 S +QH+ ID ++R + ++CT+G + +++M+++GMN+ R+N S G+ E + Sbjct: 25 SLMQHISNQSIDHAPFFVRHTNLVCTLGDHWDSDEKIDQMIKSGMNILRLNLSMGTKEKY 84 Query: 289 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 468 AE IR R E+SY +P S+ IALD P +RTGL+ A V ++ G+ + LT Sbjct: 85 AEVIRRVRRLEESYDY---NP-SVGIALDLSAPPVRTGLINESVDAVVVIQTGQMVTLTI 140 Query: 469 SPDYQEKGNADTIYVD 516 + +Y++ + I+++ Sbjct: 141 NDEYEKNTTSSIIWIN 156 >UniRef50_Q8ZNW0 Cluster: Pyruvate kinase II; n=173; Proteobacteria|Rep: Pyruvate kinase II - Salmonella typhimurium Length = 480 Score = 88.2 bits (209), Expect = 2e-16 Identities = 62/185 (33%), Positives = 94/185 (50%) Frame = +1 Query: 151 SSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSY 330 S +R + I+ T+GPA+ LEK++ G NV RMNFSHGS E H RE Sbjct: 2 SRRLRRTKIVTTLGPATDRDNNLEKVIAAGANVVRMNFSHGSPEDHKMRADKVRE----I 57 Query: 331 SAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIY 510 +AKLG +AI D +GP+IR + G +V L G+ L + E G+ + + Sbjct: 58 AAKLGR--HVAILGDLQGPKIRVSTFKEG---KVFLNIGDKFLLDANLGKGE-GDKEKVG 111 Query: 511 VDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDL 690 +DYK + V PG+ + +DDG + + V + + GG L + KG+N G + Sbjct: 112 IDYKGLPADVVPGDILLLDDGRVQLKVLEVQGMKVFTEVTVGGPLSNNKGINKLGGGLSA 171 Query: 691 PAVSE 705 A++E Sbjct: 172 EALTE 176 >UniRef50_A1IEN3 Cluster: Pyruvate kinase; n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep: Pyruvate kinase - Candidatus Desulfococcus oleovorans Hxd3 Length = 478 Score = 86.2 bits (204), Expect = 7e-16 Identities = 52/180 (28%), Positives = 93/180 (51%), Gaps = 4/180 (2%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 +I TIGP SR+ AV+EK++ G+ + R+NFSH A+ I++ RE E+ Sbjct: 5 LIATIGPRSRDRAVIEKLVAVGVTIFRLNFSHAGPGDFADVIQSVREIEQQTGT------ 58 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 L + D GP+IR G + G A + + G+ ++L + G+A + ++ I Sbjct: 59 ILTLMGDLSGPKIRIGEVAG---APLSVATGQLVRLGPARAKGAFGDALYLPLELAEILE 115 Query: 535 VVKPGNRIFIDDGL----ISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702 +KPG + + DG+ + + + +N G++ S KG++ PG+ +DLPA++ Sbjct: 116 QLKPGAPVILSDGIPVFRVRKRLDTEAGPVFELETQNSGLVSSNKGISFPGLAIDLPALT 175 >UniRef50_Q9VFG4 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: Pyruvate kinase - Drosophila melanogaster (Fruit fly) Length = 1010 Score = 85.0 bits (201), Expect = 2e-15 Identities = 42/95 (44%), Positives = 59/95 (62%) Frame = +1 Query: 109 SQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYH 288 SQL + L + + + L+ IICTIGP+S VL ++ GM V R++FS G+H+ H Sbjct: 165 SQLDYQSRLQFQAPALRLPLTSIICTIGPSSSQPEVLLNLIHAGMKVVRLDFSDGTHDCH 224 Query: 289 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEI 393 + I+ R+A Y+ + G P SLAIALDTKGP I Sbjct: 225 CQAIQAARKAIAMYAEETGLPRSLAIALDTKGPVI 259 >UniRef50_Q6F1U1 Cluster: Pyruvate kinase; n=10; Mollicutes|Rep: Pyruvate kinase - Mesoplasma florum (Acholeplasma florum) Length = 478 Score = 84.2 bits (199), Expect = 3e-15 Identities = 54/182 (29%), Positives = 89/182 (48%) Frame = +1 Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339 ++ + II T GP++ + ++ E GM R+NFSHG +E I ++ + + Sbjct: 10 VKRTKIITTTGPSTNEPEQIRELFENGMTTIRLNFSHGDYEEQGYRIAGAKKVRE----E 65 Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519 LG P S I LDTKGPEIR G G EV + TI T + ++ K Sbjct: 66 LGKPVS--ILLDTKGPEIRVGKFV-DGKQEVTANQSITI-YTDAESFKNKECLSGEMTVA 121 Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699 +++ +K G+ I IDDG + + + V + N ++ + K VNLPG+ +P + Sbjct: 122 YDMSVDLKIGDTILIDDGKLEMTVEEVKPGVVKAIAFNNHLVKTNKRVNLPGVDFSMPFL 181 Query: 700 SE 705 ++ Sbjct: 182 AQ 183 >UniRef50_Q40545 Cluster: Pyruvate kinase isozyme A, chloroplast precursor; n=15; Magnoliophyta|Rep: Pyruvate kinase isozyme A, chloroplast precursor - Nicotiana tabacum (Common tobacco) Length = 593 Score = 84.2 bits (199), Expect = 3e-15 Identities = 53/162 (32%), Positives = 81/162 (50%), Gaps = 1/162 (0%) Frame = +1 Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342 R + +ICTIGPA+ LE++ E GMNVAR+N HG+ E+H I R + Sbjct: 114 RRTKLICTIGPATCGFEQLERLAEGGMNVARINMCHGTREWHRMVIERLRRLNEE----- 168 Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522 F++AI +DT+G EI G L G SA+ E GE T + T+ V+Y Sbjct: 169 -KGFAVAIMMDTEGSEIHMGDLGGASSAKAE--DGEIWNFTVR-SFDPPLPERTVTVNYD 224 Query: 523 NITNVVKPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGML 645 VK G+ + +D G++ + + + D + C + G+L Sbjct: 225 GFAEDVKVGDELLVDGGMVRFEVIEKIGPD-VKCLCTDPGLL 265 >UniRef50_Q0C0E8 Cluster: Pyruvate kinase; n=1; Hyphomonas neptunium ATCC 15444|Rep: Pyruvate kinase - Hyphomonas neptunium (strain ATCC 15444) Length = 474 Score = 83.8 bits (198), Expect = 4e-15 Identities = 58/178 (32%), Positives = 90/178 (50%), Gaps = 1/178 (0%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 I+ T+GP SR+ + + E G++V R+NFSHG H H E ++ R AE A +G P Sbjct: 13 IVATLGPGSRSPREVRALAEAGVDVFRLNFSHGEHAAHLEALKAVRAAE----AAVGWP- 67 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 LA D +GP++R G +GG K+ I T+PD +TI V + I Sbjct: 68 -LATLADLQGPKVRVGKFDGGSLKLGFRKEYRIIVGETAPD------PETIPVPHAEIVA 120 Query: 535 VVKPGNRIFIDDG-LISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 +++ G+ I DDG LI + S + + G LG +KG + G + + A++E Sbjct: 121 ILEEGDTILADDGKLIFTVISGGSEPRVRAEVP--GKLGDKKGFTVRGKALPVRALTE 176 >UniRef50_Q1MPC8 Cluster: Pyruvate kinase; n=4; Desulfovibrionaceae|Rep: Pyruvate kinase - Lawsonia intracellularis (strain PHE/MN1-00) Length = 471 Score = 83.0 bits (196), Expect = 6e-15 Identities = 53/178 (29%), Positives = 89/178 (50%), Gaps = 1/178 (0%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 II TIGPAS + L ++++ G+++ R+NFSHG E I RE E + Sbjct: 5 IIATIGPASNSKETLSQLIQAGVSIFRLNFSHGDSSAFIELISTIRELEHIHQ------I 58 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 + I D GP+IR G L G + + KG+ + L P+ + + I D+K I + Sbjct: 59 PITIMQDLSGPKIRIGALP--GDVALNVSKGDVLCL--GPEDKRTNDYPYIPFDHKAILS 114 Query: 535 VVKPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 + + + + DG + + + S T + G++ SRKG+ LPG + +PA++E Sbjct: 115 DLVVNDILILADGTLQFQVKEQNSNGTFLLIAQEDGIITSRKGLALPGKSIKVPAITE 172 >UniRef50_Q1ZJ78 Cluster: Pyruvate kinase; n=1; Psychromonas sp. CNPT3|Rep: Pyruvate kinase - Psychromonas sp. CNPT3 Length = 485 Score = 82.6 bits (195), Expect = 9e-15 Identities = 54/178 (30%), Positives = 95/178 (53%), Gaps = 2/178 (1%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 II T+GPAS++ ++ K++ G+N+ R+NFSHGS + H + C + + SA+LG Sbjct: 6 IIATLGPASQSEDMIRKLILAGVNIVRLNFSHGSAQEHID----CAKLVRRISAELGK-- 59 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 + + +D +GP+IR + + VEL G+ L + G+ + + Y ++ Sbjct: 60 YVGVLVDLQGPKIRIACFK---NDVVELVAGQRFVLDAKL-AEFDGSVSAVGLGYPDLIA 115 Query: 535 VVKPGNRIFIDDGLISIICQSVSADTL--TCTIENGGMLGSRKGVNLPGIPVDLPAVS 702 + + + +DDG I + VS + L T + N G L +RKG+NL G + PA++ Sbjct: 116 DLNIDDVLLLDDGRIHLQVTEVSKEELKVTTKVLNSGKLSNRKGINLLGGGLSAPALT 173 >UniRef50_A3ZTM3 Cluster: Pyruvate kinase; n=1; Blastopirellula marina DSM 3645|Rep: Pyruvate kinase - Blastopirellula marina DSM 3645 Length = 490 Score = 82.6 bits (195), Expect = 9e-15 Identities = 52/176 (29%), Positives = 91/176 (51%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 I+ T+GPA +LE+M+ G++V R+N +HG + H+ RE S +L P Sbjct: 15 IVATVGPACNTPEMLEQMILAGVDVFRLNLAHGELDEHSRVATTIREI----SERLKRP- 69 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 +A D GP+IR G L VE + I+ + + E + +Y+ + + Sbjct: 70 -VATLADLSGPKIRLGTLVQDPIYCVEEQMYRFIRGDVATEPNE------LVSNYEPLID 122 Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702 VK G+ + + DG I++ + D++TC + GG+L SR+G+NLPG + + ++ Sbjct: 123 EVKVGDNVMLADGTITMEVVEKTEDSVTCVVVAGGILRSRQGINLPGTKLGVETIT 178 >UniRef50_Q5IX04 Cluster: Pyruvate kinase; n=1; Prototheca wickerhamii|Rep: Pyruvate kinase - Prototheca wickerhamii Length = 259 Score = 82.6 bits (195), Expect = 9e-15 Identities = 53/147 (36%), Positives = 83/147 (56%) Frame = +1 Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342 R + +CTIGP S + ++ + GMNV R+N SHG H H + I RE Y+A L Sbjct: 100 RKTKTVCTIGPTSCDREAFFRLADAGMNVVRLNMSHGDHASHQQVIDLVRE----YNA-L 154 Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522 G +LAI LDTKGPE+R+G L + ++L+KG+ I T G + I V+Y Sbjct: 155 GRR-NLAIMLDTKGPEVRSGDL----TQPLDLEKGDLITFTIVAG--ADGTNNRIGVNYD 207 Query: 523 NITNVVKPGNRIFIDDGLISIICQSVS 603 + V+ G+ + +D G+++++ +S S Sbjct: 208 GFIDDVEVGDMLLVDGGIMTMLVKSKS 234 >UniRef50_Q5ZZ75 Cluster: Pyruvate kinase II; n=4; Legionella pneumophila|Rep: Pyruvate kinase II - Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 /ATCC 33152 / DSM 7513) Length = 474 Score = 82.2 bits (194), Expect = 1e-14 Identities = 53/173 (30%), Positives = 89/173 (51%), Gaps = 1/173 (0%) Frame = +1 Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339 +R + I+ T+GPAS+ +L M+ G+NV R+NFSH + I R+ + + Sbjct: 2 LRRTKIVATLGPASKEPEILRSMLAAGVNVVRINFSHADSSA-LQLIALVRKI----ADE 56 Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT-SPDYQEKGNADTIYVD 516 L P +A+ D +GP+IR G + + + L G+ L +PD G+ + + V Sbjct: 57 LNHP--VAVMADLQGPKIRVGRFQ---NKSITLIDGQNFTLDCMAPD--TLGDINGVSVA 109 Query: 517 YKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPG 675 Y N+ N + G+ + I+DGLI + +S + C + GG+L KG+N G Sbjct: 110 YPNLANELSIGDHLLINDGLIELEVIEISGSKIHCKVVEGGVLTDLKGLNRKG 162 >UniRef50_Q0PQH4 Cluster: Pyruvate kinase; n=1; Endoriftia persephone 'Hot96_1+Hot96_2'|Rep: Pyruvate kinase - Endoriftia persephone 'Hot96_1+Hot96_2' Length = 246 Score = 82.2 bits (194), Expect = 1e-14 Identities = 49/181 (27%), Positives = 91/181 (50%) Frame = +1 Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342 R + I+ T+GPA+ + V++K++ G++V R+N SH H+ E R+ ++ ++ Sbjct: 36 RRTKIVATLGPATDDPKVMDKLIHAGVDVVRLNLSHDPHDQQRERAERIRDRSRASGRQV 95 Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522 G + D +GP+IR G + S V L++ L + G+ + + + Y Sbjct: 96 G------VLCDLQGPKIRIGRFK---SDFVMLEEDGAFILDAECPLTD-GDDERVGLTYP 145 Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702 ++ N V G+ + +DDG I + V + C + GG L + KG+N G + PA++ Sbjct: 146 DLINDVARGDTLLLDDGAIVLWIAEVEGKQVHCKVVVGGKLSNNKGINKQGGGLSAPALT 205 Query: 703 E 705 E Sbjct: 206 E 206 >UniRef50_Q94KE3 Cluster: Pyruvate kinase; n=25; Magnoliophyta|Rep: Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress) Length = 527 Score = 81.8 bits (193), Expect = 1e-14 Identities = 59/197 (29%), Positives = 101/197 (51%), Gaps = 10/197 (5%) Frame = +1 Query: 145 SKSSYI-RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAE 321 SKSS+ L+ I+ T+GP SR+V L ++ GM+VAR +FS G +YH ET+ N + A Sbjct: 21 SKSSFFPALTKIVGTLGPKSRSVEALSGCLKAGMSVARFDFSWGDADYHQETLDNLKVAV 80 Query: 322 KSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNAD 501 +S + KL A+ LDT GPE++ + + LK + LT P+ ++ +++ Sbjct: 81 RS-TKKL-----CAVMLDTVGPELQ---VINKSEKAITLKADGLVTLT--PNQDQEASSE 129 Query: 502 TIYVDYKNITNVVKPGNRIFIDDGLIS--------IICQSVSADTLTCTIENGGML-GSR 654 + +++ + VK G+ IF+ L + + V D + C N L GS Sbjct: 130 VLPINFNGLAKAVKKGDTIFVGQYLFTGSETTSVWLEVDEVKGDDVICLSRNAATLAGSL 189 Query: 655 KGVNLPGIPVDLPAVSE 705 ++ + +DLP ++E Sbjct: 190 FTLHSSQVHIDLPTLTE 206 >UniRef50_Q4YDL9 Cluster: Putative uncharacterized protein; n=1; Plasmodium berghei|Rep: Putative uncharacterized protein - Plasmodium berghei Length = 158 Score = 81.4 bits (192), Expect = 2e-14 Identities = 47/123 (38%), Positives = 68/123 (55%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 I+CT+GPA ++V L ++++ GM++ R NFSHG+H+ H + N +A+ Sbjct: 41 IVCTLGPACKSVETLVQLIDAGMDICRFNFSHGTHDDH-KMFENVLKAQAQ-----RPNC 94 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 +L + LD KGPEIRTGLL G+ E LK+G +KL DY G+ I Y T Sbjct: 95 TLGMLLDNKGPEIRTGLL---GNKEAHLKEGSKLKLVA--DYSYLGDETCIACSYTKCTT 149 Query: 535 VVK 543 K Sbjct: 150 KCK 152 >UniRef50_A7APT5 Cluster: Pyruvate kinase family protein; n=1; Babesia bovis|Rep: Pyruvate kinase family protein - Babesia bovis Length = 693 Score = 81.4 bits (192), Expect = 2e-14 Identities = 57/203 (28%), Positives = 99/203 (48%), Gaps = 17/203 (8%) Frame = +1 Query: 148 KSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKS 327 + ++ L+ + T+GP++ L +ME G ++ R+NFSHG+ + R R+ E Sbjct: 105 QGQFMTLTKQVSTLGPSTCTADSLRSIMEAGTDIYRLNFSHGTRLFKLRLTRMIRQLELV 164 Query: 328 YSAKLGSPFSL----AIALDTKGPEIRTGL-----------LEGGGSAEVELKKGETIKL 462 S+ GS + I D +GP++R G +E + VELKKG+ Sbjct: 165 RSSGEGSDSFMVSPKGILGDIQGPKLRIGRFMPNVDAVGKGIESSAAEFVELKKGDKFTF 224 Query: 463 TTSPDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSAD--TLTCTIENG 636 T + KG+ + ++ +I + GN I +DDG +++ SV D ++T + N Sbjct: 225 DT---HDVKGSQTRVRFNFPDILRDLNVGNTIAMDDGNLNLEVISVDRDAPSVTAVVLND 281 Query: 637 GMLGSRKGVNLPGIPVDLPAVSE 705 G+L SRKG +P + + + SE Sbjct: 282 GVLSSRKGFAVPNVAITVDLFSE 304 >UniRef50_Q07637 Cluster: Pyruvate kinase; n=44; Streptococcaceae|Rep: Pyruvate kinase - Lactococcus lactis subsp. lactis (Streptococcus lactis) Length = 502 Score = 81.4 bits (192), Expect = 2e-14 Identities = 55/173 (31%), Positives = 84/173 (48%), Gaps = 3/173 (1%) Frame = +1 Query: 196 ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 375 +++N+A L +E G NV R NFSHG H + AE+ K+G LD Sbjct: 38 SAKNIAAL---IEEGANVFRFNFSHGDHPEQGARMATVHRAEEIAGHKVG------FLLD 88 Query: 376 TKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYV-DYKNITNVVKPGN 552 TKGPE+RT L G A + + G+ ++ T + + V +I + V+ G Sbjct: 89 TKGPEMRTELFADGADA-ISVVTGDKFRVATKQGLKSTPELIALNVAGGLDIFDDVEIGQ 147 Query: 553 RIFIDDGLISIICQSVSADTLTCTIE--NGGMLGSRKGVNLPGIPVDLPAVSE 705 I IDDG + + A T +E N G++G +KGVN+P + PA++E Sbjct: 148 TILIDDGKLGLSLTGKDAATREFEVEAQNDGVIGKQKGVNIPNTKIPFPALAE 200 >UniRef50_Q9PF54 Cluster: Pyruvate kinase; n=11; Xanthomonadaceae|Rep: Pyruvate kinase - Xylella fastidiosa Length = 501 Score = 81.0 bits (191), Expect = 3e-14 Identities = 53/181 (29%), Positives = 86/181 (47%) Frame = +1 Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342 R + I+ T+GPA+ VL+ + + G+NV R+NFSHG A R A ++ Sbjct: 19 RRTRILATLGPATDPPGVLDALFKAGVNVVRLNFSHGDASDQARRAAEVRAAAAHVGVEI 78 Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522 G I D GP+IR G G V + + + + +P G+A + V Y Sbjct: 79 G------ILADLPGPKIRIGRFTEGKVRLVADARFDLLADSNAP----LGDATQVGVSYL 128 Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702 + V G+ + +DDGL+ + V + T+ N G+L RKG+N G + L A++ Sbjct: 129 GLPQDVAAGDVLLLDDGLMQLQVVQVQGARIVTTVLNDGVLSDRKGLNKQGGGLSLGALT 188 Query: 703 E 705 + Sbjct: 189 D 189 >UniRef50_A7PC98 Cluster: Chromosome chr2 scaffold_11, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr2 scaffold_11, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 475 Score = 81.0 bits (191), Expect = 3e-14 Identities = 46/147 (31%), Positives = 81/147 (55%) Frame = +1 Query: 265 SHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKK 444 SHG H H +TI +E + K+ +AI LDTKGPE+R+G + + LK+ Sbjct: 2 SHGDHASHKKTIDLVKEYNAQFEDKV-----IAIMLDTKGPEVRSGDVP----KPIMLKE 52 Query: 445 GETIKLTTSPDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCT 624 G+ T + +T+ V+Y + N V+ G+ + +D G++S++ +S S D + C Sbjct: 53 GQEFNFTIKRGVSSE---NTVSVNYDDFVNDVEVGDILLVDGGMMSLVVKSKSKDLVKCQ 109 Query: 625 IENGGMLGSRKGVNLPGIPVDLPAVSE 705 + +GG L SR+ +N+ G LP++++ Sbjct: 110 VIDGGELKSRRHLNVRGKSATLPSITD 136 >UniRef50_Q2FMN4 Cluster: Pyruvate kinase; n=1; Methanospirillum hungatei JF-1|Rep: Pyruvate kinase - Methanospirillum hungatei (strain JF-1 / DSM 864) Length = 500 Score = 80.2 bits (189), Expect = 5e-14 Identities = 54/181 (29%), Positives = 94/181 (51%) Frame = +1 Query: 151 SSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSY 330 S +R + II TIGPAS N ++ +M+ +GM++AR+N SHGS +H ET++ R Sbjct: 29 SCTMRRTKIIATIGPASSNPRIIREMILSGMDIARLNLSHGSPPWHEETVQQIRALADEL 88 Query: 331 SAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIY 510 + ++G I +D GP++R L+ S ++ G+TI + ++ + I+ Sbjct: 89 NREIG------ILVDIPGPKLRV-LIH---SPPRDVVPGDTIHIAAEHEHA----SGAIH 134 Query: 511 VDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDL 690 V + V PG+ + + DG +++ LT T+ +GG + GV +PG D+ Sbjct: 135 VHPPDCIPKVCPGDVVLVGDGAVTLQVLKPGPPMLT-TVISGGTIREGMGVVIPGRRPDV 193 Query: 691 P 693 P Sbjct: 194 P 194 >UniRef50_Q7P1G4 Cluster: Pyruvate kinase; n=4; Bacteria|Rep: Pyruvate kinase - Chromobacterium violaceum Length = 468 Score = 79.8 bits (188), Expect = 6e-14 Identities = 47/181 (25%), Positives = 89/181 (49%) Frame = +1 Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339 +R + I+ T+GP+S + ++ +G+N+ R+N SHGSH+ H + R AEK+ Sbjct: 2 LRNTKILATLGPSSSAPEKILELARSGVNIFRLNMSHGSHDDHRARLAAIRAAEKTLDRP 61 Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519 +G + +D +GP++R G +K G+ + + +GNA+ + + Sbjct: 62 IG------VLVDLQGPKLRIGKF----PQPTTVKTGDRYEFVLD---ETEGNAERATLPH 108 Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699 ++PG+ I ++DG ++ + + + GG L S KG NLP + L A+ Sbjct: 109 PEAFEALEPGHLILVNDGKLAFEVAEMHPRRIVTRVTVGGELSSNKGFNLPHTVLPLSAI 168 Query: 700 S 702 + Sbjct: 169 T 169 >UniRef50_P78031 Cluster: Pyruvate kinase; n=6; Mycoplasma|Rep: Pyruvate kinase - Mycoplasma pneumoniae Length = 508 Score = 79.8 bits (188), Expect = 6e-14 Identities = 53/167 (31%), Positives = 84/167 (50%), Gaps = 3/167 (1%) Frame = +1 Query: 211 AVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPE 390 A +E +++ G+ V R+NFSHG+HE A I+ R+ K KL P S I LDT GPE Sbjct: 42 ANIENIIKNGVTVIRLNFSHGNHEEQAVRIKIVRDVAK----KLNLPVS--IMLDTNGPE 95 Query: 391 IRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVD-YKNITNVVKPGNRIFID 567 IR + E LK E + TT+ + + N+ N VK G +I +D Sbjct: 96 IR--VFETAPEGLKILKDSEVVINTTTKEVAKNNQFSVSDASGTYNMVNDVKVGQKILVD 153 Query: 568 DGLISIICQSVSA--DTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702 DG +S++ + + + + C +N + ++K +NLP +P +S Sbjct: 154 DGKLSLVVKRIDTKNNQVICVAQNDHTIFTKKRLNLPNADYSIPFLS 200 >UniRef50_Q0AHE3 Cluster: Pyruvate kinase; n=2; Nitrosomonadaceae|Rep: Pyruvate kinase - Nitrosomonas eutropha (strain C71) Length = 483 Score = 77.8 bits (183), Expect = 2e-13 Identities = 51/167 (30%), Positives = 81/167 (48%), Gaps = 1/167 (0%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGM-NVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSP 351 IICT+GPA+ VL +++ GM +VAR N SHG H HA I+ R+ A+ Sbjct: 19 IICTLGPATDQPGVLARLIGAGMMDVARFNLSHGDHASHARRIQQVRQL-----AQQAGR 73 Query: 352 FSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNIT 531 F +A+ +D GP+ R G L G EL G + L D D + V + + Sbjct: 74 F-IAVLMDLPGPKFRLGELSNGAR---ELHLGADVILALEAD-----PPDGLPVKHPALL 124 Query: 532 NVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLP 672 ++ G +++ DG I + + A+ + C + G + S G+N+P Sbjct: 125 QALRVGESVYLADGAIRLEVKIAGAERVVCQVLVSGTVTSGSGINVP 171 >UniRef50_Q8IJ37 Cluster: Pyruvate kinase; n=7; Plasmodium|Rep: Pyruvate kinase - Plasmodium falciparum (isolate 3D7) Length = 745 Score = 77.8 bits (183), Expect = 2e-13 Identities = 58/189 (30%), Positives = 87/189 (46%), Gaps = 13/189 (6%) Frame = +1 Query: 178 ICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 357 I TIGPAS N LEK+ G++V R+NFSHG I + R EK Y +G Sbjct: 102 IATIGPASENFEQLEKLYLNGIDVFRLNFSHGLKSIKKYIINSIRILEKKYDTTIG---- 157 Query: 358 LAIALDTKGPEIRTG------LLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519 I D +GP+IR G + E + VELK+G+ GN + + ++Y Sbjct: 158 --ILGDIQGPKIRIGEFEKNQINENDNNTFVELKEGDLFSFDL---MNSLGNQNRVQLNY 212 Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADT-------LTCTIENGGMLGSRKGVNLPGI 678 + K G I +DDG + + + DT + + GG L S+KG +P + Sbjct: 213 PELIKNAKAGQIILLDDGNLKMKILENNYDTSNIQNSYIKVQVLTGGKLYSKKGFCIPNM 272 Query: 679 PVDLPAVSE 705 + + +SE Sbjct: 273 IMPIDVLSE 281 >UniRef50_A3DMY9 Cluster: Pyruvate kinase; n=1; Staphylothermus marinus F1|Rep: Pyruvate kinase - Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / F1) Length = 469 Score = 74.1 bits (174), Expect = 3e-12 Identities = 51/177 (28%), Positives = 89/177 (50%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 II TIGP+S VL ++++ G++ R+NFSHG+ E ++ RE + Y + Sbjct: 6 IITTIGPSSGKYEVLSRLIQEGVDGFRINFSHGNPHEWDEWVKMVRELAEKYERE----- 60 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 ++I D GP++R G L E+K +T+KL E+ +TI V + + Sbjct: 61 -ISIMGDLPGPQVRIGEL-----PVQEIKAKQTVKLVYKDKVDEE---NTIPVPNRKVFE 111 Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 +++ G+ + IDDG I + + + + N +L K + + G +DLP +SE Sbjct: 112 ILELGDIVLIDDGKIILRIIDIGGNEAEAIVLNDAVLYPHKTLVVFGKEIDLPVLSE 168 >UniRef50_Q8EWX2 Cluster: Pyruvate kinase; n=1; Mycoplasma penetrans|Rep: Pyruvate kinase - Mycoplasma penetrans Length = 498 Score = 73.7 bits (173), Expect = 4e-12 Identities = 55/179 (30%), Positives = 85/179 (47%), Gaps = 6/179 (3%) Frame = +1 Query: 187 IGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAI 366 I A +N+A L + G+NV R NFSHG +E + RE K +++ Sbjct: 36 IETAKKNLAAL---FDAGVNVVRFNFSHGDYEEQTIRLNLVREVAKEKGV------NIST 86 Query: 367 ALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYV----DYKNITN 534 LDTKGPEIR + EVE+K +++ T+ +E G ++ V N+ Sbjct: 87 MLDTKGPEIR---VYKTSEKEVEIKSDSKVRIYTTK--KEIGTSEKFSVLDSTGTYNMAK 141 Query: 535 VVKPGNRIFIDDG--LISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 V+PGN IF+DDG + +I +V + N +L K +NLP +P +S+ Sbjct: 142 DVQPGNTIFVDDGKLKLEVISSNVEEGIIETIARNTWILRENKRINLPDSNYSIPFMSD 200 >UniRef50_Q6L281 Cluster: Pyruvate kinase; n=2; Thermoplasmatales|Rep: Pyruvate kinase - Picrophilus torridus Length = 555 Score = 73.3 bits (172), Expect = 5e-12 Identities = 49/167 (29%), Positives = 83/167 (49%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 +I TIGPAS ++ +++KM G++ R+N +H + Y + + + KS +G Sbjct: 6 LIATIGPASESMEIIKKMANLGLSCIRINTAHIENGYITKVAKMVDDVNKSEGTYIG--- 62 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 + +D KGPE+RTG + GS +++ K I Y + N D I ++Y NI++ Sbjct: 63 ---LMVDLKGPELRTGKFK-DGSFKIDYNKKYKI------SYNKNDNPD-ILINY-NISD 110 Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPG 675 + I + DG + SV+ D + T + G L VN+PG Sbjct: 111 FIDDKTLIAMSDGKLRFSVDSVNGDIINVTSLDSGSLRDNSRVNVPG 157 >UniRef50_P32044 Cluster: Pyruvate kinase; n=2; Thermoplasma|Rep: Pyruvate kinase - Thermoplasma acidophilum Length = 544 Score = 73.3 bits (172), Expect = 5e-12 Identities = 50/177 (28%), Positives = 91/177 (51%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 I+ TIGPAS + ++++M++ G+++ R+N +H + + + +S + +G Sbjct: 5 IVATIGPASSSPEIMKQMIDNGLSLVRINSAHAD----IKDVSKITQMVRSINRDVG--- 57 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 I +D KGPE+RTG GG T+K+++ DY I ++ N+ + Sbjct: 58 ---IMIDLKGPELRTGEFAGG-----------TLKISSGKDYV---MGKDIVLNNMNVLS 100 Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 V+ G+RI + DG +S + S D T N G+L R VN+PG ++L +++ Sbjct: 101 AVQVGDRILMSDGEVSF--EVESTDPFTIRALNDGVLRDRSRVNIPGRFIELGTITD 155 >UniRef50_Q4N603 Cluster: Pyruvate kinase; n=2; Theileria|Rep: Pyruvate kinase - Theileria parva Length = 699 Score = 71.7 bits (168), Expect = 2e-11 Identities = 57/201 (28%), Positives = 100/201 (49%), Gaps = 19/201 (9%) Frame = +1 Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSH-EYH--AETIR--NCREAEK 324 + L+ + T+GPA+ N ++ + + G++V R+NFSH S H ++TIR E K Sbjct: 116 LTLTKQVATLGPATNNAESIKSLFDAGVDVFRLNFSHDSRLSKHLVSKTIRQLEINEPPK 175 Query: 325 SYSAKLGSPFS-LAIALDTKGPEIR----------TGLLEGGGSAE-VELKKGETIKLTT 468 +Y +I D +GP++R G+L G E VELK G+ L T Sbjct: 176 NYPFNGDHVVEHKSILGDIQGPKLRIGKFMPNLDVPGVLPGSKGCEFVELKAGD---LFT 232 Query: 469 SPDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLIS--IICQSVSADTLTCTIENGGM 642 Y G+ + +D+ I +K G++I +DDG +S ++ + ++T ++N Sbjct: 233 FDAYDVLGSKSRVQLDFPEILKELKVGDKILLDDGNLSMTVVKTNPEEPSVTAEVKNDYK 292 Query: 643 LGSRKGVNLPGIPVDLPAVSE 705 L SRKG ++P + + + + E Sbjct: 293 LSSRKGFSVPKVVLPIEFLDE 313 >UniRef50_A7QH42 Cluster: Chromosome chr3 scaffold_95, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr3 scaffold_95, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 573 Score = 69.7 bits (163), Expect = 6e-11 Identities = 43/162 (26%), Positives = 82/162 (50%) Frame = +1 Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339 +R + ++CTIGPA + LE + +GMNVAR+N H + E+H + IR + + Sbjct: 87 MRKTKLVCTIGPACCLLEDLENLASSGMNVARLNMCHNTWEWHRDVIRKIKRLNEE---- 142 Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519 + +++ +DT+G +I +++ G V+ + E+I L T+ + E T+ +Y Sbjct: 143 --KGYCVSVMIDTEGGQIH--VVDHGAPFSVK-AENESIWLFTTQKF-EGSRPFTVQANY 196 Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 645 + + + G+ + ID G+ S + L C + G+L Sbjct: 197 EGFSEGITVGDEVVIDGGMASFEVIEKIGNDLRCKCTDPGLL 238 >UniRef50_A2BLH1 Cluster: Pyruvate kinase; n=1; Hyperthermus butylicus DSM 5456|Rep: Pyruvate kinase - Hyperthermus butylicus (strain DSM 5456 / JCM 9403) Length = 466 Score = 66.1 bits (154), Expect = 8e-10 Identities = 50/177 (28%), Positives = 84/177 (47%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 II +IGP+S + V+ ++ E G++ R+NF+HG E REAE+ K G P Sbjct: 8 IIASIGPSSGSPEVILRLAELGVSGFRINFAHGEPSLWREWAEYVREAER----KTGRP- 62 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 LA+ D GP IR G ++ ++L G+ + + E G+ I + + + Sbjct: 63 -LALIGDLVGPSIRLGRVKN----PIKLNAGDRAEFRCVEE-SEGGDTKIIPLPVRRVYE 116 Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 V+ G+ I +DDG + + VS + + SRK + + G LP +S+ Sbjct: 117 VLDEGDLIVMDDGRVRLRVLEVSGYSAIVEALTPATITSRKAIAIRGKDPGLPTLSQ 173 >UniRef50_Q97ZD7 Cluster: Pyruvate kinase; n=4; Sulfolobaceae|Rep: Pyruvate kinase - Sulfolobus solfataricus Length = 452 Score = 64.1 bits (149), Expect = 3e-09 Identities = 54/173 (31%), Positives = 90/173 (52%) Frame = +1 Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339 +R + I+ T+GP+S K + ++V R+NF+HG H R + ++Y+ Sbjct: 1 MRKTKIVATLGPSSEEKV---KELAEYVDVFRINFAHGDETSH----RKYFDLIRTYA-- 51 Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519 P S +I +D GP++R G L+ +E+KKG+ I + +K D I VD Sbjct: 52 ---PES-SIIVDLPGPKLRLGELK----EPIEVKKGDKIV------FSQK---DGIPVDD 94 Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGI 678 + + VK + I I DG I + +S + D + T+ GG+L SRKG+N+P + Sbjct: 95 ELFYSAVKENSDILIADGTIRVRVKSKAKDRVEGTVIEGGILLSRKGINIPNV 147 >UniRef50_P19680 Cluster: Pyruvate kinase; n=1; Spiroplasma citri|Rep: Pyruvate kinase - Spiroplasma citri Length = 192 Score = 64.1 bits (149), Expect = 3e-09 Identities = 34/73 (46%), Positives = 44/73 (60%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 II TIGP++ + +E++ +TGM R+NFSHG H I RE SAK+G P Sbjct: 15 IITTIGPSTHSPGAIEELFKTGMTTIRLNFSHGDHAEQGARIVWAREV----SAKIGKPI 70 Query: 355 SLAIALDTKGPEI 393 S + LDTKGPEI Sbjct: 71 S--VLLDTKGPEI 81 >UniRef50_UPI00006CE5D4 Cluster: pyruvate kinase family protein; n=1; Tetrahymena thermophila SB210|Rep: pyruvate kinase family protein - Tetrahymena thermophila SB210 Length = 495 Score = 63.7 bits (148), Expect = 4e-09 Identities = 48/181 (26%), Positives = 82/181 (45%) Frame = +1 Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 342 R + I+CT+GP S +V ++ K++++GMNVAR+ + HG K Sbjct: 22 RKTKIVCTLGPQSSSVEMICKLLDSGMNVARITYCHG--------------------LKQ 61 Query: 343 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYK 522 G ++ D K EI+ G ++ + K+ P+Y+ G+ I Sbjct: 62 GPDIRTSLLKDKKPIEIKK-----GQKLKITFNRFLIQKVDEQPEYE--GDEQGIGCSIA 114 Query: 523 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702 ++ +V+ G + + D I V+ + EN G+L K V LPG+ +DLP +S Sbjct: 115 -LSKLVQVGQHVLLSDNTIYSHVVEVNESDIVVQFENEGILNEVKNVRLPGVKIDLPTIS 173 Query: 703 E 705 E Sbjct: 174 E 174 >UniRef50_A7QTW5 Cluster: Chromosome undetermined scaffold_171, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome undetermined scaffold_171, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 622 Score = 62.5 bits (145), Expect = 1e-08 Identities = 53/181 (29%), Positives = 89/181 (49%), Gaps = 11/181 (6%) Frame = +1 Query: 163 RLSGIICTIGP-ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339 R + I+ T+G + N ++ ++++G + R+N +HG+ +E IR R + S Sbjct: 258 RTAHIMVTVGQEVTENETLITDILKSGATIIRINCAHGNPSIWSEIIRRVRRS----SQM 313 Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGET--IKLTTSPDYQE--KGNADTI 507 L P I +D GP++RTG ++ G V L+ G+ I L +S + E + D Sbjct: 314 LEKP--CRILMDLAGPKLRTGNMKAG-PCFVRLRVGDLLIISLDSSIEQDELTQPTVDAY 370 Query: 508 YVDYKN--ITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIEN----GGMLGSRKGVNL 669 V + + + VKPG I DDG I + Q SA + +I + G LG+ K +N+ Sbjct: 371 RVTCPSSFLFDSVKPGEPIAFDDGKIWGVIQGTSASEIIVSITHASPRGTKLGAEKSINI 430 Query: 670 P 672 P Sbjct: 431 P 431 >UniRef50_A3ALA5 Cluster: Pyruvate kinase; n=3; Oryza sativa|Rep: Pyruvate kinase - Oryza sativa subsp. japonica (Rice) Length = 548 Score = 62.1 bits (144), Expect = 1e-08 Identities = 41/163 (25%), Positives = 81/163 (49%), Gaps = 1/163 (0%) Frame = +1 Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339 +R + ++CT+GPA V L + GM VAR+N HG +H +R R + Sbjct: 62 LRKTKLVCTVGPAC--VGALPALARGGMGVARVNLCHGGRGWHRAVMREVRRLNEE---- 115 Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519 F +++ +DT+G ++ + + GG+A V+ + G T+ ++ + T++V++ Sbjct: 116 --EGFCVSLMVDTEGSQLL--VADHGGAASVKAEDGSEWLFTSK--RTDESHPFTMHVNF 169 Query: 520 KNITNVVKPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGML 645 + + G+ + ID G+ + + + V D L C + G+L Sbjct: 170 DKFSEDILVGDELVIDGGMATFEVIEKVGND-LRCKCTDPGLL 211 >UniRef50_A5JEK8 Cluster: Pyruvate kinase; n=1; Nosema bombycis|Rep: Pyruvate kinase - Nosema bombycis Length = 441 Score = 61.7 bits (143), Expect = 2e-08 Identities = 46/171 (26%), Positives = 85/171 (49%) Frame = +1 Query: 166 LSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLG 345 ++ II T+ S + L ++ G+++ R+N SHG+ H +I N R+ K ++G Sbjct: 5 MTKIIVTVSSVSDDEETLTNFLKEGVHIFRINLSHGTSYQHEHSILNIRKCAK----EMG 60 Query: 346 SPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKN 525 I LDT+GPE+R + E +E+ LK+G+ K+T + ++ I++ + Sbjct: 61 --IVPVICLDTRGPEVRIEIAE---RSEIPLKEGD--KIT----FSNVRTSNKIFLPIPD 109 Query: 526 ITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGI 678 T ++I++DD +++I S T N L + K +LPG+ Sbjct: 110 FTKFPLK-SKIYLDDAMLAIEVLETSKCECTGRAMNSHRLKNNKKASLPGL 159 >UniRef50_Q8MR79 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: Pyruvate kinase - Drosophila melanogaster (Fruit fly) Length = 659 Score = 58.8 bits (136), Expect = 1e-07 Identities = 44/149 (29%), Positives = 69/149 (46%), Gaps = 4/149 (2%) Frame = +1 Query: 238 GMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTG----L 405 G+ +N G+ + I REAE S S +LG P + ++ + TG Sbjct: 175 GVRCFMVNLFEGTQHDNQSLIVKLREAEISVSKELGFPVTSSVMVKISPRHQFTGGFSTQ 234 Query: 406 LEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISI 585 G VEL +G+ + LT Y ++ NAD IYV+ + + V P + I I + I + Sbjct: 235 FRQEGKKCVELVQGQKVILTVDRQYSDRSNADVIYVNARFLIVDVHPLDFILIGED-IQL 293 Query: 586 ICQSVSADTLTCTIENGGMLGSRKGVNLP 672 + +S+ AD L + GGML + V P Sbjct: 294 MVRSIHADHLKGCVARGGMLYAHMPVLFP 322 >UniRef50_Q7NJ33 Cluster: Pyruvate kinase; n=1; Gloeobacter violaceus|Rep: Pyruvate kinase - Gloeobacter violaceus Length = 501 Score = 58.0 bits (134), Expect = 2e-07 Identities = 50/189 (26%), Positives = 82/189 (43%), Gaps = 8/189 (4%) Frame = +1 Query: 163 RLSGIICTI-GPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339 R + I+ T+ A + +L ++ GMN AR+N H S + N R AE+ Sbjct: 142 RATRIMVTLPSEAEGDYRLLCALIRAGMNCARINCVHDSETVWERMVGNIRRAEREVGR- 200 Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADT---IY 510 + I +D GP++RTG L + + L+KGE + L + D+ + Sbjct: 201 -----ACRILMDLGGPKLRTGPL----AEPLTLRKGEGLVLCRDAEEGRSACEDSPARVV 251 Query: 511 VDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTI----ENGGMLGSRKGVNLPGI 678 I V+ G + DDG I + + V+ D + I + G L + KG+N P Sbjct: 252 CAVSGIYGGVQVGEAVLFDDGKIESVVRGVAQDEIQLEITRADDKGSRLAADKGINFPES 311 Query: 679 PVDLPAVSE 705 + L +SE Sbjct: 312 RLKLRGLSE 320 >UniRef50_UPI0000E481DE Cluster: PREDICTED: hypothetical protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 461 Score = 56.8 bits (131), Expect = 5e-07 Identities = 27/35 (77%), Positives = 28/35 (80%) Frame = +1 Query: 601 SADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 SAD L C I NGGMLGSRKGVNLP VDLPA+SE Sbjct: 117 SADYLDCKIINGGMLGSRKGVNLPNAEVDLPALSE 151 >UniRef50_Q3J5D7 Cluster: Pyruvate kinase; n=2; Rhodobacter sphaeroides|Rep: Pyruvate kinase - Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM158) Length = 508 Score = 53.6 bits (123), Expect = 5e-06 Identities = 44/174 (25%), Positives = 82/174 (47%), Gaps = 4/174 (2%) Frame = +1 Query: 196 ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 375 A+ + A++ +++ G + R+N +H E A I + R++E+ KL I++D Sbjct: 161 AASDPAIVRELVAAGADAFRINCAHDGPEAWAAMIGHIRKSERMTGRKL------PISMD 214 Query: 376 TKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITNVVKPGNR 555 GP+ R + + GG L+ G+ P +G + + + + + PG + Sbjct: 215 LGGPKFR--VTKTGGPLPKRLQAGDRFAFVEKPSLAPEGRGWAM-LGHPALLAALAPGVQ 271 Query: 556 IFIDDG-LISIICQSVSADTLTCTI---ENGGMLGSRKGVNLPGIPVDLPAVSE 705 + +DDG L + + Q+ L E G L +GVNLPG +D+ A++E Sbjct: 272 VSVDDGKLWATVIQTGRGHALLEVDRVGERGLKLKPGRGVNLPGSHLDVAALTE 325 >UniRef50_P46614 Cluster: Pyruvate kinase; n=1; Candida albicans|Rep: Pyruvate kinase - Candida albicans (Yeast) Length = 92 Score = 53.6 bits (123), Expect = 5e-06 Identities = 28/69 (40%), Positives = 38/69 (55%), Gaps = 1/69 (1%) Frame = +1 Query: 463 TTSPDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSV-SADTLTCTIENGG 639 TT Y+ K + + +DYKNIT V+ PG I++DDG++S SV TL N G Sbjct: 12 TTDDAYKTKCDDKVMIIDYKNITKVIAPGKIIYVDDGVLSFEVISVDDQQTLKVRSLNAG 71 Query: 640 MLGSRKGVN 666 M+ S K N Sbjct: 72 MISSHKTAN 80 >UniRef50_A1RX09 Cluster: Pyruvate kinase; n=1; Thermofilum pendens Hrk 5|Rep: Pyruvate kinase - Thermofilum pendens (strain Hrk 5) Length = 464 Score = 52.8 bits (121), Expect = 8e-06 Identities = 40/177 (22%), Positives = 76/177 (42%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 ++ T+GP+S + +++M+ G+N R+NFSH + E + R E Sbjct: 6 LVATLGPSSWSEETMKRMVAEGVNAFRLNFSHVDYARFEELAKQVRRLETPLR------- 58 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 L + D +GP IR G A +++ G+ + T S +EK + V Sbjct: 59 PLTLIADLQGPVIRLGEF-----APFQVRPGDRVTFTLSSKTEEK---YAVPVPNGVFFE 110 Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 +V+ G+ + ++ G ++ + G + RK V + G + LP ++E Sbjct: 111 IVREGDEVLVEGGRLAFRIVDAGPEKAVGEALLEGEVKPRKTVTVRGKDIPLPTITE 167 >UniRef50_Q9PQV7 Cluster: Pyruvate kinase; n=1; Ureaplasma parvum|Rep: Pyruvate kinase - Ureaplasma parvum (Ureaplasma urealyticum biotype 1) Length = 474 Score = 52.0 bits (119), Expect = 1e-05 Identities = 45/168 (26%), Positives = 74/168 (44%), Gaps = 5/168 (2%) Frame = +1 Query: 217 LEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIR 396 ++ ++ +G+N+ RMN SHG + H + ++ K + I DTKGPEIR Sbjct: 41 IKDLILSGVNIFRMNLSHGDQKIHLFRTQLIKKIADELKIK------VEILFDTKGPEIR 94 Query: 397 TGLLEGGGSAEVELKKGETI---KLTTSPDYQEKGNADTIYVDYKNITNVVKPGNRIFID 567 + +K E I K + E D N+ + VK +RI ID Sbjct: 95 VCEMSDNNFI---IKNSEVIIHCKEKVLGSFNEFSVTDA--TGQYNMISDVKINHRILID 149 Query: 568 DGLISIICQSVS--ADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 DG + +I + + + + T +N L + K +NLP LP +S+ Sbjct: 150 DGKLILIVKKIDFLKNIIYTTAKNSYSLKTNKRLNLPDANYSLPFLSK 197 >UniRef50_Q2JJ60 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyruvate kinase - Synechococcus sp. (strain JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone B-Prime) Length = 476 Score = 49.6 bits (113), Expect = 7e-05 Identities = 42/186 (22%), Positives = 83/186 (44%), Gaps = 5/186 (2%) Frame = +1 Query: 163 RLSGIICTI-GPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339 R + I+ T+ A+ +L +++E GMNVAR+N +H + + + R+AE + Sbjct: 118 RRARIMVTLPSEAAEQPELLLQLLERGMNVARINCAHDEPSVWEKMVAHLRQAEAQTQRR 177 Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519 I LD GP+IRTG + + ++ +G+ I LT + + Sbjct: 178 ------CKILLDLAGPKIRTGPV-AMPPGKTKVYRGDRILLTAKVPEASADISCQVTCSL 230 Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIE----NGGMLGSRKGVNLPGIPVD 687 + ++ G ++IDDG I + + ++ G L + KG+N P + Sbjct: 231 PEVLAHLQVGATVWIDDGKIGARVVRIEPAGVVLEVDKVAPQGKKLRAEKGLNFPDSQLQ 290 Query: 688 LPAVSE 705 + ++++ Sbjct: 291 IRSLTD 296 >UniRef50_A6LTB0 Cluster: Pyruvate kinase; n=1; Clostridium beijerinckii NCIMB 8052|Rep: Pyruvate kinase - Clostridium beijerinckii NCIMB 8052 Length = 340 Score = 48.8 bits (111), Expect = 1e-04 Identities = 48/174 (27%), Positives = 78/174 (44%), Gaps = 6/174 (3%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 II T+GP ++ AVL+ ++E+G+N R NF HGS E E ++ ++ + Sbjct: 3 IIGTVGPNVKDRAVLKGIIESGVNALRFNFIHGSAEEFLEFLKMAKDIKS---------- 52 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQE--KGNADTIYVDYKNI 528 + + LD G ++R + G ++ GE I Y E K + + I V NI Sbjct: 53 DIQVMLDLSGTKVR---VSGKFQYIFKVYNGEVIYFCGEDKYSEVVKNSKNKIKVIPLNI 109 Query: 529 TNVV---KPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGMLGSRKGVNLPGI 678 N + K +I I D ++ I V TI GG++ KG N+ + Sbjct: 110 KNKILNEKDYKQIGIKDNTMTFDIVDKVDGLIKAITI-RGGVIRKWKGCNIKNL 162 >UniRef50_UPI000155B976 Cluster: PREDICTED: similar to pyruvate kinase, liver and RBC, partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to pyruvate kinase, liver and RBC, partial - Ornithorhynchus anatinus Length = 339 Score = 47.6 bits (108), Expect = 3e-04 Identities = 21/31 (67%), Positives = 25/31 (80%) Frame = +1 Query: 613 LTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 L +E+GG LGSRKGVN+PG +DLPAVSE Sbjct: 55 LVTEVESGGRLGSRKGVNVPGAVLDLPAVSE 85 >UniRef50_A0NLM6 Cluster: Pyruvate kinase; n=2; Alphaproteobacteria|Rep: Pyruvate kinase - Stappia aggregata IAM 12614 Length = 512 Score = 46.8 bits (106), Expect = 5e-04 Identities = 44/165 (26%), Positives = 76/165 (46%), Gaps = 6/165 (3%) Frame = +1 Query: 196 ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 375 A+ + A + ++ GMNVAR+N +H E + + R A A+L + I +D Sbjct: 165 AADDPAFVRDLVRKGMNVARLNCAHDGPEAWEKMAAHVRTA-----AELEGR-DVRILMD 218 Query: 376 TKGPEIRTGLLEGGGSAEVELKKGETIKLTT--SPDYQEKGNADTIYVDYKNITNVVKPG 549 GP+IRT + +L GE +L +PD A T V + N ++ G Sbjct: 219 IAGPKIRTETVVPQKKTP-KLTIGERFRLVVQETPD-AHSDIAVTASVSLPQMVNRLREG 276 Query: 550 NRIFIDD----GLISIICQSVSADTLTCTIENGGMLGSRKGVNLP 672 +R+ DD G++ + + +T ++G + +KG+NLP Sbjct: 277 DRLLYDDSKLEGVVEEVSNGEAVIRVTRAKDSGVKIKPQKGINLP 321 >UniRef50_Q22CT0 Cluster: Pyruvate kinase, barrel domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Pyruvate kinase, barrel domain containing protein - Tetrahymena thermophila SB210 Length = 747 Score = 46.8 bits (106), Expect = 5e-04 Identities = 43/147 (29%), Positives = 74/147 (50%), Gaps = 1/147 (0%) Frame = +1 Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREA-EKSYSAK 339 R + I+ TI + L+ M+E G+N +N ++ + + T+R R+A EK + + Sbjct: 66 RRTKIVGTISSFYSSYENLKSMVEAGLNSFMVNMAYCTPDLLV-TLRKHRDALEKEFDIQ 124 Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519 L P + + KG +R G L E+ L+KG+ ++ + ++ GN+ VD Sbjct: 125 L--PITCVL----KGTLVRIGTLM---QPEIFLRKGQEYRIVLN--HKVLGNSLYCAVDD 173 Query: 520 KNITNVVKPGNRIFIDDGLISIICQSV 600 K I VK GN+I ID G IS+ + + Sbjct: 174 KEIIRRVKVGNQILIDYGQISMTIKRI 200 >UniRef50_A3PTF7 Cluster: Pyruvate kinase; n=5; Mycobacterium|Rep: Pyruvate kinase - Mycobacterium sp. (strain JLS) Length = 615 Score = 44.8 bits (101), Expect = 0.002 Identities = 31/108 (28%), Positives = 53/108 (49%), Gaps = 1/108 (0%) Frame = +1 Query: 97 ANVGSQLQHMCGLDIDSKSSYIRLSGIICTI-GPASRNVAVLEKMMETGMNVARMNFSHG 273 ANVG +L +D+ + R + I+ T+ A+ + ++ ++ GMNVAR+N +H Sbjct: 116 ANVGDELLREHAVDLFGPAPAERATRIMVTLPSSAATDPDLVRDLIARGMNVARINCAHD 175 Query: 274 SHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGG 417 E + R A +S K +A+D GP++RTG + G Sbjct: 176 DAEAWTAMAGHVRRAAESTGRK------CLVAMDLAGPKLRTGPIRPG 217 Score = 41.5 bits (93), Expect = 0.020 Identities = 28/96 (29%), Positives = 47/96 (48%), Gaps = 6/96 (6%) Frame = +1 Query: 436 LKKGETIKLTT--SPDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSAD 609 +++G+ + LT +P + G A I + + +PG +I DDG I +V D Sbjct: 336 VQRGDELTLTRDCAPVPADHGGAPRIGCTLPEVFDHARPGEKIRFDDGRIGGEIVAVERD 395 Query: 610 TLTCTIE----NGGMLGSRKGVNLPGIPVDLPAVSE 705 L I+ G LGS KGVN+P + + A+++ Sbjct: 396 ALRVRIDRTAPGGSKLGSAKGVNVPDTHLPIAALTD 431 >UniRef50_A4ARB8 Cluster: Pyruvate kinase; n=1; Flavobacteriales bacterium HTCC2170|Rep: Pyruvate kinase - Flavobacteriales bacterium HTCC2170 Length = 624 Score = 43.6 bits (98), Expect = 0.005 Identities = 28/86 (32%), Positives = 47/86 (54%), Gaps = 2/86 (2%) Frame = +1 Query: 163 RLSGIICTI-GPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339 R + I+ T+ A+ ++ + K++ GMN AR+N +H + E + I N + A K K Sbjct: 131 RFTRIMVTLPNTAAEDLGFIRKLLANGMNCARINCAHDTPEDWLKMIDNLKIASKRQRKK 190 Query: 340 LGSPFSLAIALDTKGPEIRTG-LLEG 414 IA+D GP++RTG ++EG Sbjct: 191 C------KIAMDLSGPKLRTGPMVEG 210 Score = 33.1 bits (72), Expect = 6.8 Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 4/48 (8%) Frame = +1 Query: 541 KPGNRIFIDDGLISIICQSVSADTLTCTI----ENGGMLGSRKGVNLP 672 K G I+ DDG I I + V+A+ + I + G L + KG+NLP Sbjct: 377 KKGEPIYFDDGKIEGIIEKVTAEDIVVKITHAKDKGSKLKADKGINLP 424 >UniRef50_A7QZ91 Cluster: Chromosome undetermined scaffold_267, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome undetermined scaffold_267, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 314 Score = 42.7 bits (96), Expect = 0.008 Identities = 29/110 (26%), Positives = 53/110 (48%), Gaps = 1/110 (0%) Frame = +1 Query: 319 EKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNA 498 +K++ + F +AI +DT+G EI G L SA+ E GE I + + + Sbjct: 184 KKAFLTEQEKGFVVAIMMDTEGSEIHMGELGSAPSAKTE--DGE-IWIFSVQTFDSPRPE 240 Query: 499 DTIYVDYKNITNVVKPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGML 645 TI ++Y VK G+ + +D G++ + + + D + C + G+L Sbjct: 241 STININYDGFAEDVKVGDELLVDSGMVRFDVIEKIGPD-VKCRCTDPGLL 289 >UniRef50_Q5KVI2 Cluster: Pyruvate kinase; n=2; Geobacillus|Rep: Pyruvate kinase - Geobacillus kaustophilus Length = 660 Score = 41.9 bits (94), Expect = 0.015 Identities = 32/113 (28%), Positives = 55/113 (48%), Gaps = 2/113 (1%) Frame = +1 Query: 112 QLQHMCGLDIDSKSSYIRLSGIICTIGPA-SRNVAVLEKMMETGMNVARMNFSHGSHEYH 288 QL H + S +R + I+ T+ A ++E+++ GM++AR+N ++GS E Sbjct: 154 QLLHKRAEAVFGSPSSVRPTRIMVTMDEAWVDEPGLIERLLLYGMDIARINCAYGSPETW 213 Query: 289 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTG-LLEGGGSAEVELKK 444 + R+AEK +L I +D GP+IR L G ++ +KK Sbjct: 214 EALVAIIRQAEKQLEQQLQGR-RCRIYMDLPGPKIRVDRLAVNAGPMKLSVKK 265 >UniRef50_A6PU80 Cluster: Pyruvate kinase; n=1; Victivallis vadensis ATCC BAA-548|Rep: Pyruvate kinase - Victivallis vadensis ATCC BAA-548 Length = 121 Score = 41.9 bits (94), Expect = 0.015 Identities = 39/133 (29%), Positives = 60/133 (45%) Frame = +1 Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339 ++ + I+ TI ++ +L + + GM+V R+N +H + R+ Sbjct: 1 MKYTKIVATINASTCTEELLRGLYKNGMDVVRLNTAHMEIADMDRIVALVRKVSDK---- 56 Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519 LAI +DTKGP IRT L+ A + LK G+ + LT QEK + V+Y Sbjct: 57 ------LAIMVDTKGPNIRTCNLD----APLALKIGDKLDLTGETVPQEK----AVQVNY 102 Query: 520 KNITNVVKPGNRI 558 T V G RI Sbjct: 103 SKFTAEVPVGARI 115 >UniRef50_A1U5Q4 Cluster: Pyruvate kinase; n=2; Marinobacter aquaeolei VT8|Rep: Pyruvate kinase - Marinobacter aquaeolei (strain ATCC 700491 / DSM 11845 / VT8)(Marinobacter hydrocarbonoclasticus (strain DSM 11845)) Length = 626 Score = 41.5 bits (93), Expect = 0.020 Identities = 21/74 (28%), Positives = 41/74 (55%) Frame = +1 Query: 196 ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 375 ++++ +++ +++ GMN R+N +H E E I N + A++ + S + +D Sbjct: 154 SAQDPSIIRDLLKAGMNCMRINCAHDDPETWLEMINNLQTAKEEFGQ------SCQVFMD 207 Query: 376 TKGPEIRTGLLEGG 417 GP+IRTG +E G Sbjct: 208 LGGPKIRTGEIEPG 221 Score = 34.3 bits (75), Expect = 3.0 Identities = 19/71 (26%), Positives = 35/71 (49%), Gaps = 4/71 (5%) Frame = +1 Query: 502 TIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIEN----GGMLGSRKGVNL 669 TI + + V PG ++ DDG I + + V D I++ G L + KG+NL Sbjct: 373 TISCTMPEVVSQVHPGESVWFDDGKIGGVIEKVETDRFWVKIQHARPEGSKLRAGKGMNL 432 Query: 670 PGIPVDLPAVS 702 P +++ +++ Sbjct: 433 PDSQLNVSSLT 443 >UniRef50_Q59ZE3 Cluster: Putative uncharacterized protein; n=1; Candida albicans|Rep: Putative uncharacterized protein - Candida albicans (Yeast) Length = 105 Score = 41.5 bits (93), Expect = 0.020 Identities = 24/63 (38%), Positives = 35/63 (55%), Gaps = 1/63 (1%) Frame = -3 Query: 704 SETAGRSTGMPGRLTPFRDPSIPPFSMVHVRV-SALTD*QMIEMRPSSMKIRFPGFTTFV 528 S+ AG+ST +PG+LTP + +P +V S+ T+ + PSS + PG T V Sbjct: 43 SDKAGKSTSVPGKLTPLWEEILPALRDSTFKVCSSSTEMTSNDKTPSSTYMILPGAMTLV 102 Query: 527 MFL 519 MFL Sbjct: 103 MFL 105 >UniRef50_Q57572 Cluster: Pyruvate kinase; n=6; Methanococcales|Rep: Pyruvate kinase - Methanococcus jannaschii Length = 447 Score = 41.5 bits (93), Expect = 0.020 Identities = 52/182 (28%), Positives = 81/182 (44%) Frame = +1 Query: 160 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339 +R + I+ T+GP+ N L+K + ++ R N SH + +Y E N EK+ AK Sbjct: 5 MRKTKILVTLGPSLENK--LDKAINL-IDGVRFNMSHATTDY-CEKFLNI--LEKNNIAK 58 Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDY 519 + +D KG +IR ++ LK GE K+ D + N DTI Sbjct: 59 V---------MDLKGIKIRIKEVKLKNKI---LKMGE--KVVIGEDIKLNYNIDTI---- 100 Query: 520 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 699 + G+ I I+DG I + D + +E GG + GVNLP ++LP + Sbjct: 101 -------EEGHFILINDGKIKLRVVE-KTDKIIAVVEVGGEIKEGMGVNLPDTRIELPII 152 Query: 700 SE 705 E Sbjct: 153 DE 154 >UniRef50_Q4IUP8 Cluster: Pyruvate kinase; n=1; Azotobacter vinelandii AvOP|Rep: Pyruvate kinase - Azotobacter vinelandii AvOP Length = 165 Score = 40.7 bits (91), Expect = 0.034 Identities = 18/51 (35%), Positives = 29/51 (56%) Frame = +1 Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCRE 315 R + I+ T+G A+ +E +++ G++V R+NFSHG E H RE Sbjct: 3 RRTKIVATLGSATETPEAIEGLVKAGVDVVRLNFSHGKAEEHQARATLVRE 53 >UniRef50_A6PUS2 Cluster: Pyruvate kinase; n=1; Victivallis vadensis ATCC BAA-548|Rep: Pyruvate kinase - Victivallis vadensis ATCC BAA-548 Length = 357 Score = 40.3 bits (90), Expect = 0.045 Identities = 18/52 (34%), Positives = 28/52 (53%) Frame = +1 Query: 547 GNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 702 G RI DDG + ++ S L C + G L + K VN+PG + +PA++ Sbjct: 2 GARIIFDDGAMELLVLGKSGGLLHCEAKRDGELKNHKSVNVPGAELKMPALT 53 >UniRef50_Q9V2V8 Cluster: Pyruvate kinase; n=1; Thermoproteus tenax|Rep: Pyruvate kinase - Thermoproteus tenax Length = 446 Score = 40.3 bits (90), Expect = 0.045 Identities = 36/167 (21%), Positives = 75/167 (44%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 I+ T+GP++ + + ++ V R+N SH S + R+ E++ S Sbjct: 5 IVATLGPSTDRLPDITALLSKVHGV-RINMSHASPSEVEARVNAVRKYEET------SGR 57 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 +AI D +GP +RTGL+ +++ G + + EKG+ + V + Sbjct: 58 YIAIIADLRGPSVRTGLMR-----PLQITAGARVSFKLA----EKGDG-FVPVPRREFFE 107 Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPG 675 V++ G+ + + DG + + S + + + G++ S K + + G Sbjct: 108 VIEEGDEVLMLDGKLVLRIISAAQTSAEAESLSSGVISSNKAIVVKG 154 >UniRef50_A4VPY3 Cluster: Pyruvate kinase; n=1; Pseudomonas stutzeri A1501|Rep: Pyruvate kinase - Pseudomonas stutzeri (strain A1501) Length = 625 Score = 39.9 bits (89), Expect = 0.060 Identities = 24/69 (34%), Positives = 39/69 (56%) Frame = +1 Query: 196 ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 375 A+ N ++E +++ GM+ AR+N +H + I + R AEK+ LG +ALD Sbjct: 150 AAHNRDLIEALIKEGMDCARINCAHDDPDSWRAMIEHVRAAEKA----LGR--ECKVALD 203 Query: 376 TKGPEIRTG 402 GP++RTG Sbjct: 204 LAGPKLRTG 212 >UniRef50_Q8DLH6 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep: Pyruvate kinase - Synechococcus elongatus (Thermosynechococcus elongatus) Length = 506 Score = 39.5 bits (88), Expect = 0.079 Identities = 42/152 (27%), Positives = 62/152 (40%), Gaps = 3/152 (1%) Frame = +1 Query: 226 MMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGL 405 ++ GMN AR+N +H I + R A S G P I +D GP+ R Sbjct: 160 LLRKGMNCARVNCAHDDPATWEAMIEHLRAA----SHITGQP--CKILMDLGGPKPRIAD 213 Query: 406 LEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLIS- 582 + V + G+ ++LTT E G I ++ G R++IDDG Sbjct: 214 I---FPETVRVHSGDRLRLTTE-ICPEGGEIPQFTCSLPEIVPQLEVGQRVWIDDGRTGG 269 Query: 583 -IICQSVSADTLTCT-IENGGMLGSRKGVNLP 672 I+ + LT T + G L KG+N P Sbjct: 270 RIVSKDAQGVELTITHCKEGQRLKVAKGLNFP 301 >UniRef50_Q9VVH0 Cluster: CG12229-PA; n=2; Sophophora|Rep: CG12229-PA - Drosophila melanogaster (Fruit fly) Length = 571 Score = 39.5 bits (88), Expect = 0.079 Identities = 38/165 (23%), Positives = 75/165 (45%), Gaps = 12/165 (7%) Frame = +1 Query: 214 VLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKS-----------YSAKLGSPFSL 360 V + + ET + R +G++ +H +T+ N + K+ +SA+ + Sbjct: 78 VAKLVTETTHDELRRMLENGTYTFHVDTVGNKPDELKAILDTMNIAISAHSAERELRLTT 137 Query: 361 AIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYV-DYKNITNV 537 +AL+ G R G L + V L +G + LTT Y+ KG + +YV + + Sbjct: 138 GLALEINGECCRVGRLRN--NCTVMLARGGVVTLTTDESYRYKGFKEIVYVINLRCYLAS 195 Query: 538 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLP 672 V+ G+ + I + + +++ + LT I + G++ S + LP Sbjct: 196 VQLGDIVMIGREVRGKVVKTL-REALTVMIIDAGLVASYDFIELP 239 >UniRef50_Q5M6U9 Cluster: Pyruvate kinase; n=2; Campylobacter jejuni|Rep: Pyruvate kinase - Campylobacter jejuni Length = 319 Score = 38.7 bits (86), Expect = 0.14 Identities = 40/177 (22%), Positives = 78/177 (44%) Frame = +1 Query: 175 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 354 +I T GP+ L ++ + + R+N +HG E TI N R+ + Sbjct: 4 LILTTGPSLGGKINLNQIHQDKF-IYRINGAHGDIESIKNTIINLRKQKAD--------- 53 Query: 355 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 + I +D G +IRT G S ++++K + L +YK Sbjct: 54 -IDILIDLPGNKIRTS----GISEAIQVEKDKDFSLKIDQ------------FNYKEFYK 96 Query: 535 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 +VKPG ++ +D + I + V+ + T ++ G+L + KG+++ + ++P + E Sbjct: 97 LVKPGMEVYANDSVFLFIVKEVNDKEIIFTSKSTGLLLNNKGMHVRNLHDNIPFLFE 153 >UniRef50_Q9M3B6 Cluster: Pyruvate kinase; n=1; Arabidopsis thaliana|Rep: Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress) Length = 710 Score = 37.1 bits (82), Expect = 0.42 Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 1/86 (1%) Frame = +1 Query: 163 RLSGIICTIGP-ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 339 R + I+ TIG A+ + + +++ G +V R+N +HG E I+ R S Sbjct: 234 RSTHIMVTIGEEATLSETFITDILKAGTSVIRINCAHGDPSIWGEIIKRVRRT----SQM 289 Query: 340 LGSPFSLAIALDTKGPEIRTGLLEGG 417 L P + +D GP++RTG L+ G Sbjct: 290 LEMP--CRVHMDLAGPKLRTGTLKPG 313 >UniRef50_UPI00006CB055 Cluster: hypothetical protein TTHERM_00239360; n=1; Tetrahymena thermophila SB210|Rep: hypothetical protein TTHERM_00239360 - Tetrahymena thermophila SB210 Length = 1220 Score = 36.7 bits (81), Expect = 0.55 Identities = 19/66 (28%), Positives = 34/66 (51%) Frame = +1 Query: 325 SYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADT 504 S S + + F+ LDT GP + + ++++K E+IK+ + YQ KGN+ Sbjct: 924 SKSQQNSNQFNQGNQLDTLGPFENNAVQNSLENISLKIEKNESIKIQSKDIYQNKGNSQF 983 Query: 505 IYVDYK 522 + +D K Sbjct: 984 LNIDQK 989 >UniRef50_Q8XLL6 Cluster: Pyruvate kinase; n=3; Clostridium perfringens|Rep: Pyruvate kinase - Clostridium perfringens Length = 364 Score = 35.9 bits (79), Expect = 0.97 Identities = 39/167 (23%), Positives = 69/167 (41%), Gaps = 4/167 (2%) Frame = +1 Query: 217 LEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIR 396 ++ +++ G N+ RMN SHG H R+ E + ++ I LD +G +IR Sbjct: 30 IDNIVKGGGNIIRMNLSHGKH----------RDVECCIDYIRSNHKNVKILLDLQGNKIR 79 Query: 397 TGLLEGGGSAEVELKKGETIKLTTSPDYQE-KGNADTIYVDYKNITNVVKPGN---RIFI 564 + ++ G+ + + Y N D + NI N N +I++ Sbjct: 80 ---VANNIYGTFKVNSGDLVYFCSEETYDAYLKNIDRNKLIPLNIKNKFIYNNTFKKIYM 136 Query: 565 DDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 D + I S + + ++ GG++ KG NLP + VSE Sbjct: 137 KDATMEFIVISNNNGLIKTKVKLGGVVRKEKGCNLPNLDRKNWGVSE 183 >UniRef50_A0V3R8 Cluster: S-layer-like region; n=1; Clostridium cellulolyticum H10|Rep: S-layer-like region - Clostridium cellulolyticum H10 Length = 1382 Score = 35.5 bits (78), Expect = 1.3 Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 4/100 (4%) Frame = +1 Query: 364 IALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIY-VDYKNI--TN 534 I ++ ++R +L+G E+E+ KGE I +T S E D I V NI T Sbjct: 243 IKIEKNNNKLRIVILDGNTVKEIEIAKGEEIIVTGSVGTLEIATPDVIVKVIAANISDTK 302 Query: 535 VVKPGNRIFID-DGLISIICQSVSADTLTCTIENGGMLGS 651 VV IF+D + I + + SA+ E G ++ + Sbjct: 303 VVSANASIFVDKESKIKSVSINNSAENTAIKAEKGAVVNT 342 >UniRef50_UPI0000DB7164 Cluster: PREDICTED: similar to CG31559-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to CG31559-PA - Apis mellifera Length = 739 Score = 35.1 bits (77), Expect = 1.7 Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 3/68 (4%) Frame = +1 Query: 466 TSPDYQEKGNADTIYV--DYKNIT-NVVKPGNRIFIDDGLISIICQSVSADTLTCTIENG 636 T P +K N+ T+ + D N T ++ G + DD +I C S++ LT I NG Sbjct: 293 TPPPLPKKKNSSTVILASDQHNRTGSLTSSGAEVDSDDNESNISCDSLNGGELTDRIANG 352 Query: 637 GMLGSRKG 660 G+ G+ G Sbjct: 353 GINGNEAG 360 >UniRef50_Q8FLV7 Cluster: Pyruvate kinase; n=6; Corynebacterium|Rep: Pyruvate kinase - Corynebacterium efficiens Length = 630 Score = 35.1 bits (77), Expect = 1.7 Identities = 28/107 (26%), Positives = 44/107 (41%), Gaps = 12/107 (11%) Frame = +1 Query: 421 SAEVELKKGETIKLTTSPDYQEK----GNADTIYVDYKNITNVVKPGNRIFIDDGLISII 588 S + LK G + LT+ + G I +K G+R+ DDG I+ + Sbjct: 331 SQRINLKVGNRLFLTSEEVVYDPSAGHGRIPKISCTLPEAVGAIKVGHRVLFDDGSIAAV 390 Query: 589 C--------QSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 705 C V +T G L + KG+NLP + LP+++E Sbjct: 391 CIDRREHDGHHVVELEVTRARPQGVNLAAYKGINLPDSELPLPSLTE 437 >UniRef50_A2STG1 Cluster: Putative anti-sigma regulatory factor, serine/threonine protein kinase; n=1; Methanocorpusculum labreanum Z|Rep: Putative anti-sigma regulatory factor, serine/threonine protein kinase - Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z) Length = 777 Score = 35.1 bits (77), Expect = 1.7 Identities = 17/48 (35%), Positives = 25/48 (52%) Frame = +1 Query: 130 GLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHG 273 G ID K +YI+ SG+IC G A + V +KM G + ++ G Sbjct: 349 GTGIDVKGTYIQNSGMICGTGMAGDGICVAKKMTVYGGKIEATGYTTG 396 >UniRef50_A3CQV6 Cluster: Conserved uncharacterized protein; n=9; Streptococcus|Rep: Conserved uncharacterized protein - Streptococcus sanguinis (strain SK36) Length = 133 Score = 34.7 bits (76), Expect = 2.2 Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 1/85 (1%) Frame = +1 Query: 337 KLGSPFSLAIALDTKG-PEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYV 513 K+ S +LA AL G +T +G SA+ +KK I ++ +PD QEK Sbjct: 3 KIFSLLTLAFALLLVGCGSSQTNTDKGSSSADSSVKKELKISISIAPDGQEKSEKTVAVE 62 Query: 514 DYKNITNVVKPGNRIFIDDGLISII 588 + K + +K ++ DG I+ I Sbjct: 63 EGKTAMDALKKAYKVEEKDGFITSI 87 >UniRef50_Q89VQ2 Cluster: ABC transporter peptide-binding protein; n=1; Bradyrhizobium japonicum|Rep: ABC transporter peptide-binding protein - Bradyrhizobium japonicum Length = 532 Score = 34.3 bits (75), Expect = 3.0 Identities = 20/63 (31%), Positives = 30/63 (47%) Frame = +1 Query: 304 NCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQ 483 N + + S A L S ++ ++RT + G VE K E+IKLT +PDY Sbjct: 159 NLKRPQPSLLALLASGYTPVYPCHVSPGDMRTHPIGTGPFKFVEFKANESIKLTRNPDYW 218 Query: 484 EKG 492 +G Sbjct: 219 REG 221 >UniRef50_A5NL17 Cluster: ATP-dependent Clp protease, ATP-binding subunit ClpA; n=1; Shewanella baltica OS223|Rep: ATP-dependent Clp protease, ATP-binding subunit ClpA - Shewanella baltica OS223 Length = 66 Score = 34.3 bits (75), Expect = 3.0 Identities = 20/51 (39%), Positives = 29/51 (56%), Gaps = 4/51 (7%) Frame = +1 Query: 316 AEKSYSAKLGS-PFSLAIALDTKGP---EIRTGLLEGGGSAEVELKKGETI 456 AEK Y +G+ P + + K P EI G+LE GG A V++K+GE + Sbjct: 3 AEKGYDKNMGARPMARVVTELIKRPLADEILFGVLESGGVAHVDVKEGELV 53 >UniRef50_Q4CYW8 Cluster: Putative uncharacterized protein; n=3; Trypanosoma|Rep: Putative uncharacterized protein - Trypanosoma cruzi Length = 435 Score = 34.3 bits (75), Expect = 3.0 Identities = 36/144 (25%), Positives = 60/144 (41%), Gaps = 7/144 (4%) Frame = +1 Query: 163 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREA--EKSYSA 336 R+SG++ T+ P + A+ E + +A + +H E HA+ C A E+ S+ Sbjct: 30 RVSGLLFTVNPRQESKALRELQLYLHPLIADLEEAHKRVEEHADARGRCDNATTEEQSSS 89 Query: 337 KLGSPFSLAIALDTK---GPEIRTGLLEGGGSAEVELKK--GETIKLTTSPDYQEKGNAD 501 K+ + IA T E+ + GG E+++ + K S D EK + D Sbjct: 90 KMSTDAGGKIAPSTSSLLAAELAEYITTRGGQRRHEMRRIPMKEEKSDVSDDEDEKKSTD 149 Query: 502 TIYVDYKNITNVVKPGNRIFIDDG 573 + N +N NR D G Sbjct: 150 NNNNNNNNNSNNNILRNRSSDDGG 173 >UniRef50_A3CLR6 Cluster: Fibril-like structure subunit FibA, putative; n=1; Streptococcus sanguinis SK36|Rep: Fibril-like structure subunit FibA, putative - Streptococcus sanguinis (strain SK36) Length = 1273 Score = 33.5 bits (73), Expect = 5.2 Identities = 18/57 (31%), Positives = 31/57 (54%), Gaps = 2/57 (3%) Frame = +1 Query: 370 LDTKGPEIRTG--LLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIYVDYKNITN 534 LD K ++ G L+ G +E KKG+T+ + +P+Y + ++ I + YK TN Sbjct: 372 LDYKELKVEAGGNALQEGRDYTIE-KKGQTVTVKMTPEYVKANSSQDIVITYKTATN 427 >UniRef50_Q58MH8 Cluster: Putative uncharacterized protein; n=1; Cyanophage P-SSM2|Rep: Putative uncharacterized protein - Cyanophage P-SSM2 Length = 331 Score = 33.5 bits (73), Expect = 5.2 Identities = 26/68 (38%), Positives = 37/68 (54%), Gaps = 5/68 (7%) Frame = +1 Query: 370 LDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEK---GNADTIYVDYKNIT--N 534 LD K P+I TG+++G A ++L GET + P YQ K T V+ K I + Sbjct: 117 LDDKIPDIMTGIIKGCEIAGMDLLGGETAE---HPQYQMKIDLAGFCTGIVEKKKIIDGS 173 Query: 535 VVKPGNRI 558 V+KP +RI Sbjct: 174 VIKPSDRI 181 >UniRef50_Q8EYH8 Cluster: MutS-like mismatch repair protein, ATPases; n=4; Leptospira|Rep: MutS-like mismatch repair protein, ATPases - Leptospira interrogans Length = 610 Score = 33.1 bits (72), Expect = 6.8 Identities = 49/171 (28%), Positives = 73/171 (42%), Gaps = 22/171 (12%) Frame = +1 Query: 130 GLDIDSKSSYIRLSGIICTIG------PASR-NVAVLEKMMETGMNVARMNFSHGSHEYH 288 G ++ K++Y+R G+ + PAS+ ++ VL+ + T M N G ++ Sbjct: 441 GSNMSGKTTYLRTIGVASILSMAGGPVPASKFSLPVLK--IHTSMR-NEDNLEEGISFFY 497 Query: 289 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 468 AE +R E K K S L + KG R L G + ELKK TI T Sbjct: 498 AE-VRRLSEIVKKIRDKNSSHLVLLDEI-LKGTNTRERSLACKGILK-ELKKNRTIVFVT 554 Query: 469 SPD-------------YQEKGNADTIYVDYKNITNVVKPGN--RIFIDDGL 576 S D +QE+ T+Y DYK +V+ N RI + +GL Sbjct: 555 SHDLELAKVEGVILKHFQEEVLDGTMYFDYKIREGLVETSNALRILVQEGL 605 >UniRef50_Q2AHN9 Cluster: Radical SAM; n=1; Halothermothrix orenii H 168|Rep: Radical SAM - Halothermothrix orenii H 168 Length = 231 Score = 33.1 bits (72), Expect = 6.8 Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 3/72 (4%) Frame = +1 Query: 364 IALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSPDYQEKGNADTIY---VDYKNITN 534 IA+D K P R GLL G ++K+ I L ++ DY+ + Y D I Sbjct: 120 IAMDIKAPFSRYGLLAGSSKYNNQIKESINILLNSNIDYEFRTTVIPGYHTENDLIKIAE 179 Query: 535 VVKPGNRIFIDD 570 ++K R FI + Sbjct: 180 LIKGAGRYFIQN 191 >UniRef50_Q3EBL2 Cluster: Uncharacterized protein At2g37440.1; n=3; Arabidopsis thaliana|Rep: Uncharacterized protein At2g37440.1 - Arabidopsis thaliana (Mouse-ear cress) Length = 479 Score = 33.1 bits (72), Expect = 6.8 Identities = 18/40 (45%), Positives = 22/40 (55%) Frame = -2 Query: 639 TSVFNGTRKSVSADRLTDDRDEAIVDEDSVSWLHDIRYVL 520 T +F TR S S+ D R E I+D D V WL D+ Y L Sbjct: 276 TEIFKRTRFSRSSK---DSRPETIMDHDKVIWLGDLNYRL 312 >UniRef50_Q46513 Cluster: ORF 2 gene product; n=1; Desulfurococcus mobilis|Rep: ORF 2 gene product - Desulfurococcus mobilis Length = 87 Score = 32.7 bits (71), Expect = 9.0 Identities = 23/87 (26%), Positives = 44/87 (50%) Frame = +1 Query: 226 MMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGL 405 M+ G R+N +HG E ++ RE S++L ++ + LDT GP++R+G Sbjct: 1 MVREGAAGFRINCAHGDEADWLEYVKIVREV----SSELDQ--AIPLILDTPGPQVRSGD 54 Query: 406 LEGGGSAEVELKKGETIKLTTSPDYQE 486 + E ++ +G+ + + PD +E Sbjct: 55 FQ-----EFKVVRGDKVLFSMDPDAKE 76 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.135 0.390 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 715,959,678 Number of Sequences: 1657284 Number of extensions: 14737923 Number of successful extensions: 51288 Number of sequences better than 10.0: 175 Number of HSP's better than 10.0 without gapping: 48868 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 51042 length of database: 575,637,011 effective HSP length: 98 effective length of database: 413,223,179 effective search space used: 56198352344 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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