Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Nnor0108
(604 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M86826-1|AAA36047.1| 605|Homo sapiens insulin-like growth facto... 108 2e-23
AL031724-2|CAC36078.1| 605|Homo sapiens C447E6.2 (insulin-like ... 108 2e-23
AF192554-1|AAF06774.1| 605|Homo sapiens acid-labile subunit pro... 108 2e-23
BC025681-1|AAH25681.1| 605|Homo sapiens insulin-like growth fac... 107 3e-23
J05158-1|AAA51921.2| 545|Homo sapiens carboxypeptidase N precur... 100 4e-21
BC031569-1|AAH31569.2| 545|Homo sapiens carboxypeptidase N, pol... 100 4e-21
BC042334-1|AAH42334.2| 545|Homo sapiens carboxypeptidase N, pol... 99 1e-20
BC033039-1|AAH33039.1| 927|Homo sapiens LGR4 protein protein. 98 2e-20
AB209743-1|BAD92980.1| 1032|Homo sapiens Leucine-rich repeat-con... 97 4e-20
BC101065-1|AAI01066.1| 581|Homo sapiens LRRC15 protein protein. 95 2e-19
BC101064-1|AAI01065.1| 581|Homo sapiens leucine rich repeat con... 95 2e-19
BC096326-1|AAH96326.1| 883|Homo sapiens LGR5 protein protein. 94 4e-19
BC096325-1|AAH96325.1| 883|Homo sapiens LGR5 protein protein. 94 4e-19
AF346711-1|AAK31153.1| 951|Homo sapiens G-protein couple recept... 93 5e-19
AF257182-1|AAF68989.1| 951|Homo sapiens G-protein-coupled recep... 93 5e-19
BC099650-1|AAH99650.1| 907|Homo sapiens leucine-rich repeat-con... 92 2e-18
BC096324-1|AAH96324.1| 907|Homo sapiens leucine-rich repeat-con... 92 2e-18
AF062006-1|AAC28019.1| 907|Homo sapiens orphan G protein-couple... 92 2e-18
AB071037-1|BAB84587.1| 581|Homo sapiens Lib protein. 91 4e-18
AF061444-1|AAC77911.1| 907|Homo sapiens G protein-coupled recep... 90 6e-18
BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats an... 89 1e-17
BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats an... 89 1e-17
AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and immuno... 89 1e-17
AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein. 89 1e-17
AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein. 89 1e-17
BC047905-1|AAH47905.2| 915|Homo sapiens leucine-rich repeat-con... 88 2e-17
AY358119-1|AAQ88486.1| 915|Homo sapiens gonadotropin receptor p... 88 2e-17
AL356953-3|CAI15929.1| 915|Homo sapiens leucine-rich repeat-con... 88 2e-17
AL356953-1|CAI15927.1| 967|Homo sapiens leucine-rich repeat-con... 88 2e-17
AB049405-1|BAB39854.1| 928|Homo sapiens VTS20631 protein. 88 2e-17
AY358733-1|AAQ89095.1| 622|Homo sapiens CGLQ1891 protein. 86 8e-17
AY280614-1|AAP36706.1| 622|Homo sapiens synleurin protein. 86 8e-17
AK123022-1|BAC85517.1| 622|Homo sapiens protein ( Homo sapiens ... 86 8e-17
BC034389-1|AAH34389.1| 347|Homo sapiens leucine-rich alpha-2-gl... 85 1e-16
AB073607-1|BAD38644.1| 347|Homo sapiens leucine-rich alpha-2-gl... 85 1e-16
BC070198-1|AAH70198.1| 347|Homo sapiens leucine-rich alpha-2-gl... 85 2e-16
AF403428-1|AAK95527.1| 347|Homo sapiens leucine-rich alpha-2-gl... 85 2e-16
BC126410-1|AAI26411.1| 516|Homo sapiens leucine rich repeat tra... 84 3e-16
BC126408-1|AAI26409.1| 516|Homo sapiens leucine rich repeat tra... 84 3e-16
AY182026-1|AAO67547.1| 516|Homo sapiens leucine-rich repeat tra... 84 3e-16
AB007876-1|BAA24846.2| 529|Homo sapiens KIAA0416 protein. 84 3e-16
BC117276-1|AAI17277.1| 420|Homo sapiens reticulon 4 receptor-li... 84 4e-16
BC113673-1|AAI13674.1| 420|Homo sapiens reticulon 4 receptor-li... 84 4e-16
AY250221-1|AAP82838.1| 420|Homo sapiens nogo receptor-like 3 pr... 84 4e-16
AF532858-1|AAP21835.1| 420|Homo sapiens Nogo-66 receptor homolo... 84 4e-16
BC043165-1|AAH43165.1| 719|Homo sapiens leucine rich repeat and... 81 3e-15
AK055365-1|BAB70910.1| 719|Homo sapiens protein ( Homo sapiens ... 81 3e-15
BC068590-1|AAH68590.1| 778|Homo sapiens LOC150356 protein protein. 81 4e-15
BC003193-1|AAH03193.1| 524|Homo sapiens leucine rich repeat con... 81 4e-15
AL513211-1|CAI17358.1| 524|Homo sapiens leucine rich repeat con... 81 4e-15
AL035681-1|CAI22653.1| 762|Homo sapiens protein ( Human DNA seq... 81 4e-15
AL033384-1|CAI21666.1| 524|Homo sapiens leucine rich repeat con... 81 4e-15
AK021896-1|BAB13929.1| 197|Homo sapiens protein ( Homo sapiens ... 81 4e-15
AF359380-1|AAK72246.1| 524|Homo sapiens LANO adaptor protein pr... 81 4e-15
AF332199-1|AAK69623.1| 524|Homo sapiens leucine-rich repeats pr... 81 4e-15
U88879-1|AAC34134.1| 904|Homo sapiens Toll-like receptor 3 prot... 80 7e-15
DQ445682-1|ABE01399.1| 904|Homo sapiens Toll-like receptor 3 is... 80 7e-15
BC096335-1|AAH96335.1| 904|Homo sapiens toll-like receptor 3 pr... 80 7e-15
BC096334-1|AAH96334.1| 904|Homo sapiens toll-like receptor 3 pr... 80 7e-15
BC096333-1|AAH96333.1| 904|Homo sapiens toll-like receptor 3 pr... 80 7e-15
BC094737-1|AAH94737.1| 904|Homo sapiens toll-like receptor 3 pr... 80 7e-15
BC059372-1|AAH59372.1| 870|Homo sapiens TLR3 protein protein. 80 7e-15
BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosoph... 79 9e-15
BC045113-1|AAH45113.1| 522|Homo sapiens LRRTM1 protein protein. 79 9e-15
AY358310-1|AAQ88677.1| 522|Homo sapiens DFLL675 protein. 79 9e-15
AY182024-1|AAO67545.1| 522|Homo sapiens leucine-rich repeat tra... 79 9e-15
AK056644-1|BAB71240.1| 522|Homo sapiens protein ( Homo sapiens ... 79 9e-15
AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein. 79 9e-15
AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellula... 79 9e-15
AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein. 79 9e-15
Z93015-1|CAI42364.1| 481|Homo sapiens nyctalopin protein. 79 2e-14
BC113717-1|AAI13718.1| 581|Homo sapiens leucine rich repeat tra... 79 2e-14
BC113715-1|AAI13716.1| 581|Homo sapiens leucine rich repeat tra... 79 2e-14
BC112242-1|AAI12243.1| 481|Homo sapiens nyctalopin protein. 79 2e-14
BC111745-1|AAI11746.1| 653|Homo sapiens leucine rich repeat con... 79 2e-14
BC111561-1|AAI11562.1| 653|Homo sapiens leucine rich repeat con... 79 2e-14
BC111492-1|AAI11493.1| 581|Homo sapiens leucine rich repeat tra... 79 2e-14
AY358315-1|AAQ88681.1| 513|Homo sapiens GFNV803 protein. 79 2e-14
AY358307-1|AAQ88674.1| 653|Homo sapiens NAG14 protein. 79 2e-14
AY182028-1|AAO67549.1| 513|Homo sapiens leucine-rich repeat tra... 79 2e-14
AJ278865-1|CAC19014.1| 481|Homo sapiens leucine-rich repeat pro... 79 2e-14
AF254868-1|AAG42685.1| 481|Homo sapiens nyctalopin protein. 79 2e-14
AF196976-1|AAG28019.2| 653|Homo sapiens brain tumor associated ... 79 2e-14
Z23091-1|CAA80637.1| 560|Homo sapiens platelet glycoprotein V p... 78 2e-14
L11238-1|AAA03069.1| 560|Homo sapiens platelet membrane glycopr... 78 2e-14
BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats an... 78 2e-14
BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats an... 78 2e-14
AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats an... 78 2e-14
AK172751-1|BAD18737.1| 653|Homo sapiens protein ( Homo sapiens ... 78 2e-14
AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein. 78 2e-14
BC146759-1|AAI46760.1| 1523|Homo sapiens slit homolog 3 (Drosoph... 78 3e-14
BC040188-1|AAH40188.1| 692|Homo sapiens LOC150356 protein protein. 78 3e-14
AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein. 78 3e-14
AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein. 78 3e-14
AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein. 78 3e-14
BC131897-1|AAI31898.1| 420|Homo sapiens LRRC4B protein protein. 77 5e-14
BC041374-1|AAH41374.3| 640|Homo sapiens LRRC4C protein protein. 77 5e-14
BC036337-1|AAH36337.1| 811|Homo sapiens KIAA0644 gene product p... 77 5e-14
BC032460-1|AAH32460.1| 634|Homo sapiens LRRC4B protein protein. 77 5e-14
AY358293-1|AAQ88660.1| 640|Homo sapiens LNKM292 protein. 77 5e-14
AB046800-1|BAB13406.1| 640|Homo sapiens KIAA1580 protein protein. 77 5e-14
AB014544-1|BAA31619.2| 887|Homo sapiens KIAA0644 protein protein. 77 5e-14
BC030608-1|AAH30608.1| 661|Homo sapiens podocan protein. 77 6e-14
BC028292-1|AAH28292.1| 402|Homo sapiens PODN protein protein. 77 6e-14
AY358294-1|AAQ88661.1| 642|Homo sapiens EGEE293 protein. 77 6e-14
AY313607-1|AAP79898.1| 613|Homo sapiens podocan protein protein. 76 8e-14
AL445183-5|CAH72592.1| 642|Homo sapiens podocan protein. 76 1e-13
AL445183-4|CAH72591.1| 661|Homo sapiens podocan protein. 76 1e-13
DQ084201-1|AAY86708.1| 640|Homo sapiens netrin-G1 ligand splice... 75 1e-13
BC110058-1|AAI10059.1| 518|Homo sapiens leucine rich repeat tra... 75 2e-13
BC099738-1|AAH99738.1| 518|Homo sapiens leucine rich repeat tra... 75 2e-13
BC098301-1|AAH98301.1| 519|Homo sapiens LRRTM4 protein protein. 75 2e-13
BC098267-1|AAH98267.1| 519|Homo sapiens LRRTM4 protein protein. 75 2e-13
AY358324-1|AAQ88690.1| 590|Homo sapiens GFHL3075 protein. 75 2e-13
AY182030-1|AAO67551.1| 518|Homo sapiens leucine-rich repeat tra... 75 2e-13
AK126961-1|BAC86764.1| 518|Homo sapiens protein ( Homo sapiens ... 75 2e-13
AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat pro... 74 4e-13
BC111013-1|AAI11014.1| 428|Homo sapiens immunoglobulin superfam... 73 6e-13
BC022478-1|AAH22478.1| 428|Homo sapiens immunoglobulin superfam... 73 6e-13
AY358871-1|AAQ89230.1| 428|Homo sapiens ISLR protein. 73 6e-13
AK223267-1|BAD96987.1| 428|Homo sapiens immunoglobulin superfam... 73 6e-13
AB024537-1|BAA85971.1| 428|Homo sapiens ISLR protein. 73 6e-13
AB024536-1|BAA85970.1| 428|Homo sapiens ISLR protein. 73 6e-13
AB003184-1|BAA22848.1| 428|Homo sapiens ISLR protein. 73 6e-13
AL159161-1|CAI17102.1| 754|Homo sapiens relaxin/insulin-like fa... 73 8e-13
AL138708-1|CAH73785.1| 754|Homo sapiens relaxin/insulin-like fa... 73 8e-13
AF453828-1|AAL73946.1| 754|Homo sapiens G protein-coupled recep... 73 8e-13
AF403384-1|AAL69324.2| 754|Homo sapiens LGR8 protein. 73 8e-13
BC046356-1|AAH46356.1| 421|Homo sapiens osteomodulin protein. 72 1e-12
AY358872-1|AAQ89231.1| 421|Homo sapiens OMD protein. 72 1e-12
AL137848-4|CAI16696.1| 421|Homo sapiens osteomodulin protein. 72 1e-12
AB009589-1|BAA23982.1| 421|Homo sapiens Osteomodulin protein. 72 1e-12
AB000114-1|BAA19055.1| 421|Homo sapiens osteomodulin protein. 72 1e-12
DQ084202-1|AAY86709.1| 640|Homo sapiens netrin-G1 ligand splice... 72 2e-12
BC073974-1|AAH73974.1| 359|Homo sapiens chondroadherin protein. 72 2e-12
BC036360-1|AAH36360.1| 359|Homo sapiens chondroadherin protein. 72 2e-12
AF371328-1|AAK51556.1| 359|Homo sapiens chondroadherin protein. 72 2e-12
AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein L... 71 2e-12
AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein L... 71 2e-12
AY029183-1|AAK31796.1| 798|Homo sapiens SLIT1 isoform B protein. 71 3e-12
AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 71 3e-12
AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 71 3e-12
AL512424-3|CAI14257.1| 409|Homo sapiens slit homolog 1 (Drosoph... 71 3e-12
AL512424-1|CAI14255.1| 782|Homo sapiens slit homolog 1 (Drosoph... 71 3e-12
AL442123-4|CAH70918.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 71 3e-12
AL442123-3|CAH70917.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 71 3e-12
BC146761-1|AAI46762.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 71 4e-12
BC142616-1|AAI42617.1| 789|Homo sapiens leucine rich repeat and... 71 4e-12
BC003578-1|AAH03578.1| 628|Homo sapiens leucine rich repeat and... 71 4e-12
AY358127-1|AAQ88494.1| 627|Homo sapiens AILP5865 protein. 71 4e-12
AL591063-1|CAI15264.1| 789|Homo sapiens RP11-535K1.2 protein. 71 4e-12
AK172754-1|BAD18740.1| 628|Homo sapiens protein ( Homo sapiens ... 71 4e-12
AB033072-1|BAA86560.1| 832|Homo sapiens KIAA1246 protein protein. 71 4e-12
AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein. 71 4e-12
AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein. 71 4e-12
BC129927-1|AAI29928.1| 1323|Homo sapiens PH domain and leucine r... 70 6e-12
BC035267-1|AAH35267.1| 723|Homo sapiens PHLPPL protein protein. 70 6e-12
AB040917-1|BAA96008.1| 700|Homo sapiens KIAA1484 protein protein. 70 6e-12
AB023148-1|BAA76775.2| 1258|Homo sapiens KIAA0931 protein protein. 70 6e-12
U96769-1|AAC13410.1| 359|Homo sapiens chondroadherin protein. 70 7e-12
BC068558-1|AAH68558.1| 614|Homo sapiens LINGO1 protein protein. 70 7e-12
AY358115-1|AAQ88482.1| 593|Homo sapiens DAAT9248 protein. 69 1e-11
AL589765-16|CAI17178.1| 593|Homo sapiens leucine rich repeat an... 69 1e-11
CR456360-1|CAG30246.1| 473|Homo sapiens Em:AC007663.1 protein. 69 1e-11
BC071866-1|AAH71866.1| 460|Homo sapiens LRFN4 protein protein. 69 1e-11
BC015581-1|AAH15581.2| 635|Homo sapiens leucine rich repeat and... 69 1e-11
BC011787-1|AAH11787.1| 473|Homo sapiens reticulon 4 receptor pr... 69 1e-11
BC007718-1|AAH07718.1| 541|Homo sapiens LRFN4 protein protein. 69 1e-11
AY358297-1|AAQ88664.1| 473|Homo sapiens NOGOR protein. 69 1e-11
AF283463-1|AAG53612.1| 473|Homo sapiens Nogo receptor protein. 69 1e-11
AB209005-1|BAD92242.1| 622|Homo sapiens leucine rich repeat and... 69 1e-11
BC050445-1|AAH50445.1| 582|Homo sapiens soc-2 suppressor of cle... 69 2e-11
BC011057-1|AAH11057.2| 620|Homo sapiens leucine rich repeat and... 69 2e-11
AY899851-1|AAX85199.1| 730|Homo sapiens LGR8.1 protein. 69 2e-11
AY324320-1|AAQ97216.1| 620|Homo sapiens leucine-rich repeat neu... 69 2e-11
AL834260-1|CAD38935.1| 577|Homo sapiens hypothetical protein pr... 69 2e-11
AL158163-2|CAH72812.1| 582|Homo sapiens soc-2 suppressor of cle... 69 2e-11
AF068920-1|AAC39856.1| 582|Homo sapiens Ras-binding protein SUR... 69 2e-11
AF054828-1|AAC25698.1| 582|Homo sapiens leucine-rich repeat pro... 69 2e-11
AB020669-1|BAA74885.2| 584|Homo sapiens KIAA0862 protein protein. 69 2e-11
BC115015-1|AAI15016.1| 1367|Homo sapiens ERBB2IP protein protein. 68 2e-11
BC115012-1|AAI15013.1| 1371|Homo sapiens erbb2 interacting prote... 68 2e-11
BC071561-1|AAH71561.1| 1070|Homo sapiens LRIG1 protein protein. 68 2e-11
BC050692-1|AAH50692.1| 633|Homo sapiens ERBB2IP protein protein. 68 2e-11
AL391728-2|CAH73692.1| 1495|Homo sapiens leucine rich repeat con... 68 2e-11
AL391728-1|CAH73691.1| 1537|Homo sapiens leucine rich repeat con... 68 2e-11
AL359412-2|CAH74019.1| 1495|Homo sapiens leucine rich repeat con... 68 2e-11
AL359412-1|CAH74018.1| 1537|Homo sapiens leucine rich repeat con... 68 2e-11
AL158840-2|CAH70975.1| 1495|Homo sapiens leucine rich repeat con... 68 2e-11
AL158840-1|CAH70974.1| 1537|Homo sapiens leucine rich repeat con... 68 2e-11
AL157948-2|CAI22426.1| 1495|Homo sapiens leucine rich repeat con... 68 2e-11
AL157948-1|CAI22425.1| 1537|Homo sapiens leucine rich repeat con... 68 2e-11
AL117353-1|CAI23423.1| 1495|Homo sapiens leucine rich repeat con... 68 2e-11
AF434715-1|AAL28133.1| 1537|Homo sapiens densin-180 protein. 68 2e-11
AF276423-1|AAK69431.1| 1412|Homo sapiens densin-180-like protein... 68 2e-11
AF263744-1|AAF77048.1| 1371|Homo sapiens erbb2-interacting prote... 68 2e-11
AB033051-1|BAA86539.2| 1371|Homo sapiens KIAA1225 protein protein. 68 2e-11
BC058935-1|AAH58935.1| 239|Homo sapiens LRRC57 protein protein. 67 4e-11
AY358284-1|AAQ88651.1| 620|Homo sapiens QVSK201 protein. 67 4e-11
AL513211-2|CAI17359.1| 154|Homo sapiens leucine rich repeat con... 67 4e-11
AL356953-5|CAI15931.1| 232|Homo sapiens leucine-rich repeat-con... 67 4e-11
AL158163-3|CAH72813.1| 372|Homo sapiens soc-2 suppressor of cle... 67 4e-11
AL122074-1|CAB59249.1| 333|Homo sapiens hypothetical protein pr... 67 4e-11
AK094891-1|BAC04451.1| 239|Homo sapiens protein ( Homo sapiens ... 67 4e-11
AK094131-1|BAC04294.1| 239|Homo sapiens (EC 2.4.1.101). protein. 67 4e-11
D63481-1|BAA09768.3| 1630|Homo sapiens KIAA0147 protein protein. 66 7e-11
AY062238-1|AAL38976.1| 1630|Homo sapiens scribble protein. 66 7e-11
AL512424-2|CAI14256.1| 380|Homo sapiens slit homolog 1 (Drosoph... 66 7e-11
AF240677-1|AAP88017.1| 1630|Homo sapiens CRIB1 protein. 66 7e-11
AB016816-1|BAA74737.1| 1052|Homo sapiens MASL1 protein. 66 7e-11
AJ297858-1|CAC82651.1| 649|Homo sapiens hypothetical protein pr... 66 9e-11
BC126464-1|AAI26465.1| 1371|Homo sapiens erbb2 interacting prote... 66 1e-10
BC113617-1|AAI13618.1| 757|Homo sapiens relaxin/insulin-like fa... 65 2e-10
BC112142-1|AAI12143.1| 757|Homo sapiens leucine-rich repeat-con... 65 2e-10
AY899850-1|AAX85198.1| 724|Homo sapiens LGR7.10 protein. 65 2e-10
AF190500-1|AAG17167.1| 757|Homo sapiens leucine-rich repeat-con... 65 2e-10
BC150568-1|AAI50569.1| 370|Homo sapiens leucine-rich repeats an... 65 2e-10
AK095610-1|BAC04589.1| 370|Homo sapiens protein ( Homo sapiens ... 65 2e-10
BC035281-1|AAH35281.1| 376|Homo sapiens fibromodulin protein. 64 3e-10
BC008586-1|AAH08586.1| 602|Homo sapiens leucine rich repeat con... 64 3e-10
BC003407-1|AAH03407.2| 581|Homo sapiens LRRC40 protein protein. 64 3e-10
AL359837-1|CAH73821.1| 376|Homo sapiens fibromodulin protein. 64 3e-10
AL353771-3|CAI22332.1| 602|Homo sapiens leucine rich repeat con... 64 3e-10
AK022951-1|BAB14326.1| 602|Homo sapiens protein ( Homo sapiens ... 64 3e-10
X72913-1|CAA51418.1| 376|Homo sapiens fibromodulin protein. 64 4e-10
AY358114-1|AAQ88481.1| 606|Homo sapiens Tango hlg protein. 64 4e-10
AL353746-1|CAC22713.1| 606|Homo sapiens leucine rich repeat and... 64 4e-10
AK172834-1|BAD18799.1| 459|Homo sapiens protein ( Homo sapiens ... 64 4e-10
AK056372-1|BAB71167.1| 606|Homo sapiens protein ( Homo sapiens ... 64 4e-10
BC126277-1|AAI26278.1| 1205|Homo sapiens PH domain and leucine r... 64 5e-10
BC082244-1|AAH82244.1| 465|Homo sapiens PHLPP protein protein. 64 5e-10
BC014927-1|AAH14927.3| 1205|Homo sapiens PH domain and leucine r... 64 5e-10
AK001924-1|BAA91980.1| 721|Homo sapiens protein ( Homo sapiens ... 64 5e-10
AC108017-1|AAY41039.1| 260|Homo sapiens unknown protein. 64 5e-10
AB011178-1|BAA25532.2| 1369|Homo sapiens KIAA0606 protein protein. 64 5e-10
M22403-1|AAA52596.1| 626|Homo sapiens platelet membrane glycopr... 63 6e-10
J02940-1|AAA52595.1| 626|Homo sapiens GP1BA protein. 63 6e-10
BC048421-1|AAH48421.1| 453|Homo sapiens LOC150356 protein protein. 63 6e-10
BC027955-1|AAH27955.1| 626|Homo sapiens glycoprotein Ib (platel... 63 6e-10
AM709890-1|CAM97225.1| 639|Homo sapiens platelet glycoprotein I... 63 6e-10
AF395009-1|AAK71325.1| 626|Homo sapiens glycoprotein Ib (platel... 63 6e-10
AB086948-1|BAC10305.1| 626|Homo sapiens platelet glycoprotein I... 63 6e-10
AB038516-1|BAB12038.1| 626|Homo sapiens platelet glycoprotein I... 63 6e-10
L12535-1|AAA60292.1| 277|Homo sapiens RSU-1 protein. 63 8e-10
CR541840-1|CAG46639.1| 277|Homo sapiens RSU1 protein. 63 8e-10
CR536521-1|CAG38758.1| 277|Homo sapiens RSU1 protein. 63 8e-10
BC107898-1|AAI07899.1| 280|Homo sapiens RSU1 protein protein. 63 8e-10
BC057786-1|AAH57786.1| 512|Homo sapiens podocan-like 1 protein. 63 8e-10
BC015644-1|AAH15644.1| 277|Homo sapiens Ras suppressor protein ... 63 8e-10
BC008691-1|AAH08691.1| 277|Homo sapiens RSU1 protein protein. 63 8e-10
BC005993-1|AAH05993.1| 277|Homo sapiens Ras suppressor protein ... 63 8e-10
AL365215-3|CAH73633.1| 277|Homo sapiens Ras suppressor protein ... 63 8e-10
X75546-1|CAA53233.1| 376|Homo sapiens fibromodulin protein. 62 1e-09
AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608 pr... 62 1e-09
AL356953-4|CAI15930.1| 828|Homo sapiens leucine-rich repeat-con... 62 1e-09
AF190501-1|AAG17168.1| 828|Homo sapiens leucine-rich repeat-con... 62 1e-09
BC044233-1|AAH44233.1| 692|Homo sapiens leucine rich repeat con... 62 1e-09
BC034947-1|AAH34947.1| 716|Homo sapiens leucine rich repeat neu... 62 1e-09
BC033651-1|AAH33651.1| 1049|Homo sapiens toll-like receptor 7 pr... 62 1e-09
AY358322-1|AAQ88688.1| 692|Homo sapiens ELLP3030 protein. 62 1e-09
AY358312-1|AAQ88679.1| 716|Homo sapiens NLRR protein. 62 1e-09
AY358292-1|AAQ88659.1| 1049|Homo sapiens TLR7 protein. 62 1e-09
AY358116-1|AAQ88483.1| 548|Homo sapiens LGI3 protein. 62 1e-09
AJ487961-1|CAD32308.1| 548|Homo sapiens LGI1-like protein 4 pro... 62 1e-09
AJ487518-1|CAD31786.1| 548|Homo sapiens leucine-rich glioma ina... 62 1e-09
AF467956-1|AAM49554.1| 548|Homo sapiens LGI3 protein. 62 1e-09
AF240467-1|AAF60188.1| 1049|Homo sapiens toll-like receptor 7 pr... 62 1e-09
AB074161-1|BAE45733.1| 716|Homo sapiens neuronal leucine-rich r... 62 1e-09
AB040930-1|BAA96021.1| 730|Homo sapiens KIAA1497 protein protein. 62 1e-09
BC128608-1|AAI28609.1| 441|Homo sapiens reticulon 4 receptor-li... 62 2e-09
BC113973-1|AAI13974.1| 803|Homo sapiens factor for adipocyte di... 62 2e-09
AY250219-1|AAP82836.1| 441|Homo sapiens nogo receptor-like 2 pr... 62 2e-09
AF532859-1|AAP21836.1| 441|Homo sapiens Nogo-66 receptor homolo... 62 2e-09
AB081509-1|BAB86303.1| 803|Homo sapiens AD158 protein. 62 2e-09
BC009239-1|AAH09239.1| 723|Homo sapiens leucine rich repeat and... 61 3e-09
AY358830-1|AAQ89189.1| 723|Homo sapiens leucine-rich protein pr... 61 3e-09
AL445222-17|CAH72931.1| 696|Homo sapiens leucine rich repeat an... 61 3e-09
AL445222-16|CAH72930.1| 723|Homo sapiens leucine rich repeat an... 61 3e-09
AK091589-1|BAC03703.1| 723|Homo sapiens protein ( Homo sapiens ... 61 3e-09
AK056203-1|BAB71119.1| 696|Homo sapiens protein ( Homo sapiens ... 61 3e-09
AK001637-1|BAA91801.1| 183|Homo sapiens protein ( Homo sapiens ... 61 3e-09
BT007440-1|AAP36108.1| 353|Homo sapiens hypothetical protein, e... 60 4e-09
BC020975-1|AAH20975.1| 353|Homo sapiens tsukushin protein. 60 4e-09
AY358317-1|AAQ88683.1| 353|Homo sapiens E2IG4 protein. 60 4e-09
AY358316-1|AAQ88682.1| 745|Homo sapiens FPLR1885 protein. 60 4e-09
AF191019-1|AAF09483.1| 353|Homo sapiens E2IG4 protein. 60 4e-09
AB040898-1|BAA95989.2| 785|Homo sapiens KIAA1465 protein protein. 60 4e-09
BC101761-1|AAI01762.1| 545|Homo sapiens leucine-rich repeat LGI... 60 6e-09
BC101759-1|AAI01760.1| 545|Homo sapiens leucine-rich repeat LGI... 60 6e-09
BC101073-1|AAI01074.1| 841|Homo sapiens SLIT and NTRK-like fami... 60 6e-09
BC101072-1|AAI01073.1| 841|Homo sapiens SLIT and NTRK-like fami... 60 6e-09
BC101071-1|AAI01072.1| 841|Homo sapiens SLIT and NTRK-like fami... 60 6e-09
BC101070-1|AAI01071.1| 841|Homo sapiens SLIT and NTRK-like fami... 60 6e-09
BC080586-1|AAH80586.1| 743|Homo sapiens MXRA5 protein protein. 60 6e-09
BC064986-1|AAH64986.1| 743|Homo sapiens MXRA5 protein protein. 60 6e-09
BC040986-1|AAH40986.1| 837|Homo sapiens SLIT and NTRK-like fami... 60 6e-09
BC011846-1|AAH11846.1| 743|Homo sapiens MXRA5 protein protein. 60 6e-09
AL713693-1|CAD28493.1| 689|Homo sapiens hypothetical protein pr... 60 6e-09
AL080239-3|CAI41650.1| 837|Homo sapiens novel protein protein. 60 6e-09
AK057619-1|BAB71535.1| 469|Homo sapiens protein ( Homo sapiens ... 60 6e-09
AK027100-1|BAB15657.1| 363|Homo sapiens protein ( Homo sapiens ... 60 6e-09
AJ487958-1|CAD32305.1| 545|Homo sapiens LGI1-like protein 2 pro... 60 6e-09
AJ487516-1|CAD31784.1| 545|Homo sapiens leucine-rich glioma ina... 60 6e-09
AF467955-1|AAM49553.1| 545|Homo sapiens LGI2 protein. 60 6e-09
AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein. 60 6e-09
AB208943-1|BAD92180.1| 627|Homo sapiens leucine-rich repeat-con... 60 6e-09
AB067503-1|BAB67809.1| 542|Homo sapiens KIAA1916 protein protein. 60 6e-09
BC074741-1|AAH74741.1| 345|Homo sapiens leucine-rich repeats an... 60 8e-09
BC020870-1|AAH20870.1| 649|Homo sapiens fibronectin leucine ric... 60 8e-09
AY358319-1|AAQ88685.1| 649|Homo sapiens FLRT3 protein. 60 8e-09
AL132826-1|CAB86687.1| 649|Homo sapiens fibronectin leucine ric... 60 8e-09
AK074909-1|BAC11284.1| 649|Homo sapiens protein ( Homo sapiens ... 60 8e-09
AK074883-1|BAC11265.1| 627|Homo sapiens protein ( Homo sapiens ... 60 8e-09
AK027694-1|BAB55303.1| 623|Homo sapiens protein ( Homo sapiens ... 60 8e-09
AK027297-1|BAB55023.1| 649|Homo sapiens protein ( Homo sapiens ... 60 8e-09
AF225421-1|AAG09723.1| 345|Homo sapiens HT017 protein. 60 8e-09
AF169677-1|AAF28461.1| 649|Homo sapiens leucine-rich repeat tra... 60 8e-09
AB040902-1|BAA95993.1| 662|Homo sapiens KIAA1469 protein protein. 60 8e-09
BC110418-1|AAI10419.1| 504|Homo sapiens adhesion molecule with ... 59 1e-08
BC101365-1|AAI01366.1| 504|Homo sapiens adhesion molecule with ... 59 1e-08
BC101364-1|AAI01365.1| 504|Homo sapiens adhesion molecule with ... 59 1e-08
BC101363-1|AAI01364.1| 504|Homo sapiens adhesion molecule with ... 59 1e-08
BC013757-1|AAH13757.1| 403|Homo sapiens LRRC58 protein protein. 59 1e-08
AY358134-1|AAQ88501.1| 504|Homo sapiens TWLV6084 protein. 59 1e-08
AY237003-1|AAO48944.1| 504|Homo sapiens transmembrane protein A... 59 1e-08
AB058754-1|BAB47480.1| 523|Homo sapiens KIAA1851 protein protein. 59 1e-08
BC068575-1|AAH68575.1| 673|Homo sapiens vasorin protein. 59 1e-08
BC013767-1|AAH13767.1| 601|Homo sapiens VASN protein protein. 59 1e-08
AY358299-1|AAQ88666.1| 673|Homo sapiens CSRV314 protein. 59 1e-08
AY166584-1|AAO27704.1| 673|Homo sapiens vasorin protein. 59 1e-08
U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein. 58 2e-08
U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog prot... 58 2e-08
BC114551-1|AAI14552.1| 334|Homo sapiens ISLR2 protein protein. 58 2e-08
BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog (D... 58 2e-08
AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog va... 58 2e-08
BC108252-1|AAI08253.1| 532|Homo sapiens LRRC8E protein protein. 58 3e-08
BC070089-1|AAH70089.1| 796|Homo sapiens leucine rich repeat con... 58 3e-08
BC022216-1|AAH22216.2| 592|Homo sapiens LRRC8E protein protein. 58 3e-08
AL834474-1|CAD39133.1| 622|Homo sapiens hypothetical protein pr... 58 3e-08
AK027073-1|BAB15648.1| 444|Homo sapiens protein ( Homo sapiens ... 58 3e-08
BC150572-1|AAI50573.1| 337|Homo sapiens LRRC55 protein protein. 57 4e-08
AK127591-1|BAC87047.1| 341|Homo sapiens protein ( Homo sapiens ... 57 4e-08
AF245702-1|AAF78035.1| 1049|Homo sapiens toll-like receptor 7 pr... 57 4e-08
Y19205-1|CAC80724.1| 845|Homo sapiens SLITL1 protein. 57 5e-08
U41344-1|AAC18782.1| 382|Homo sapiens prolargin protein. 57 5e-08
U29089-1|AAC50230.1| 382|Homo sapiens proline- arginine-rich en... 57 5e-08
CR542270-1|CAG47066.1| 382|Homo sapiens PRELP protein. 57 5e-08
BC113012-1|AAI13013.1| 845|Homo sapiens SLIT and NTRK-like fami... 57 5e-08
BC113011-1|AAI13012.1| 845|Homo sapiens SLIT and NTRK-like fami... 57 5e-08
BC068541-1|AAH68541.1| 713|Homo sapiens leucine rich repeat neu... 57 5e-08
BC034047-1|AAH34047.1| 713|Homo sapiens leucine rich repeat neu... 57 5e-08
BC032498-1|AAH32498.1| 382|Homo sapiens proline/arginine-rich e... 57 5e-08
AY358828-1|AAQ89187.1| 733|Homo sapiens LSGV9197 protein. 57 5e-08
AY358290-1|AAQ88657.1| 713|Homo sapiens GAC1 protein. 57 5e-08
AL512306-1|CAI14096.1| 713|Homo sapiens leucine rich repeat neu... 57 5e-08
AL391817-1|CAI17033.1| 382|Homo sapiens proline/arginine-rich e... 57 5e-08
AL109653-2|CAC18888.1| 845|Homo sapiens SLIT and NTRK-like fami... 57 5e-08
AL109653-1|CAI41645.1| 724|Homo sapiens SLIT and NTRK-like fami... 57 5e-08
AK091015-1|BAC03566.1| 724|Homo sapiens protein ( Homo sapiens ... 57 5e-08
AF030435-1|AAC39792.1| 713|Homo sapiens glioma amplified on chr... 57 5e-08
AB058757-1|BAB47483.1| 572|Homo sapiens KIAA1854 protein protein. 57 5e-08
DQ355157-1|ABC79623.1| 334|Homo sapiens cytokeratin associated ... 56 7e-08
BC024159-1|AAH24159.2| 858|Homo sapiens leucine rich repeat con... 56 7e-08
AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase prot... 56 7e-08
AY358874-1|AAQ89233.1| 501|Homo sapiens LRRC5 protein. 56 7e-08
AL929554-11|CAH72880.1| 334|Homo sapiens leucine rich repeat co... 56 7e-08
AL391497-3|CAH72226.1| 858|Homo sapiens leucine rich repeat con... 56 7e-08
AK222787-1|BAD96507.1| 671|Homo sapiens leucine rich repeat con... 56 7e-08
AK001332-1|BAA91631.1| 682|Homo sapiens protein ( Homo sapiens ... 56 7e-08
U18728-1|AAA85268.1| 338|Homo sapiens lumican protein. 56 1e-07
BC130290-1|AAI30291.1| 660|Homo sapiens fibronectin leucine ric... 56 1e-07
BC126249-1|AAI26250.1| 660|Homo sapiens fibronectin leucine ric... 56 1e-07
BC103509-1|AAI03510.1| 958|Homo sapiens SLIT and NTRK-like fami... 56 1e-07
BC098287-1|AAH98287.1| 958|Homo sapiens SLIT and NTRK-like fami... 56 1e-07
BC098106-1|AAH98106.1| 958|Homo sapiens SLIT and NTRK-like fami... 56 1e-07
BC051322-1|AAH51322.1| 810|Homo sapiens leucine rich repeat con... 56 1e-07
BC032667-1|AAH32667.1| 352|Homo sapiens keratocan protein. 56 1e-07
AY358287-1|AAQ88654.1| 660|Homo sapiens FLRT2 protein. 56 1e-07
AY358286-1|AAQ88653.1| 546|Homo sapiens RQTI221 protein. 56 1e-07
AY143166-1|AAN18279.1| 810|Homo sapiens leucine-rich repeat-con... 56 1e-07
AL672142-1|CAI10839.1| 810|Homo sapiens leucine rich repeat con... 56 1e-07
AL603883-1|CAH73026.1| 958|Homo sapiens SLIT and NTRK-like fami... 56 1e-07
AK027495-1|BAB55153.1| 474|Homo sapiens protein ( Homo sapiens ... 56 1e-07
AK001199-1|BAA91549.1| 221|Homo sapiens protein ( Homo sapiens ... 56 1e-07
AF205403-1|AAF69126.1| 352|Homo sapiens keratocan protein. 56 1e-07
AF169676-1|AAF28460.1| 660|Homo sapiens leucine-rich repeat tra... 56 1e-07
AF065988-1|AAC17741.1| 352|Homo sapiens keratocan protein. 56 1e-07
AF063301-1|AAC16390.1| 352|Homo sapiens keratan sulfate proteog... 56 1e-07
AB037858-1|BAA92675.1| 811|Homo sapiens KIAA1437 protein protein. 56 1e-07
AB020725-1|BAA74941.1| 966|Homo sapiens KIAA0918 protein protein. 56 1e-07
AB007865-1|BAA23701.2| 706|Homo sapiens KIAA0405 protein. 56 1e-07
Z94160-2|CAI22122.1| 820|Homo sapiens protein ( Human DNA seque... 56 1e-07
U93091-1|AAC80227.1| 839|Homo sapiens Toll protein homolog prot... 56 1e-07
U88880-1|AAC34135.1| 799|Homo sapiens Toll-like receptor 4 prot... 56 1e-07
BC125224-1|AAI25225.1| 748|Homo sapiens LRCH2 protein protein. 56 1e-07
BC117422-1|AAI17423.1| 839|Homo sapiens toll-like receptor 4 pr... 56 1e-07
BC109119-1|AAI09120.1| 858|Homo sapiens TLR5 protein protein. 56 1e-07
AL160272-2|CAH72619.1| 799|Homo sapiens toll-like receptor 4 pr... 56 1e-07
AL160272-1|CAH72618.1| 839|Homo sapiens toll-like receptor 4 pr... 56 1e-07
AF177766-1|AAF07823.1| 752|Homo sapiens human toll-like recepto... 56 1e-07
AF177765-1|AAF05316.1| 839|Homo sapiens toll-like receptor 4 pr... 56 1e-07
AF172171-1|AAF89753.1| 839|Homo sapiens toll-like receptor 4 pr... 56 1e-07
AB067491-1|BAB67797.1| 821|Homo sapiens KIAA1904 protein protein. 56 1e-07
X57436-1|CAA40684.1| 440|Homo sapiens oligodentrocyte-myelin gl... 55 2e-07
X51694-1|CAA35991.1| 433|Homo sapiens oligodendrocyte-myelin gl... 55 2e-07
U21128-1|AAA91639.1| 338|Homo sapiens lumican protein. 55 2e-07
M63623-1|AAA59970.1| 440|Homo sapiens oligodendrocyte-myelin gl... 55 2e-07
CR541787-1|CAG46586.1| 382|Homo sapiens PRELP protein. 55 2e-07
BT006707-1|AAP35353.1| 338|Homo sapiens lumican protein. 55 2e-07
BC040879-1|AAH40879.1| 493|Homo sapiens adhesion molecule with ... 55 2e-07
BC035997-1|AAH35997.1| 338|Homo sapiens lumican protein. 55 2e-07
BC018050-1|AAH18050.1| 440|Homo sapiens oligodendrocyte myelin ... 55 2e-07
BC007038-1|AAH07038.1| 338|Homo sapiens lumican protein. 55 2e-07
AY237007-1|AAO48948.1| 493|Homo sapiens transmembrane protein A... 55 2e-07
AL355145-6|CAI22942.1| 493|Homo sapiens adhesion molecule with ... 55 2e-07
AK222663-1|BAD96383.1| 440|Homo sapiens oligodendrocyte myelin ... 55 2e-07
AF075240-1|AAD19336.1| 850|Homo sapiens SLIT1 protein protein. 55 2e-07
BC018370-1|AAH18370.1| 674|Homo sapiens fibronectin leucine ric... 55 2e-07
BC009613-1|AAH09613.1| 335|Homo sapiens leucine rich repeat con... 55 2e-07
AY358308-1|AAQ88675.1| 674|Homo sapiens FLRT1 protein. 55 2e-07
AY358131-1|AAQ88498.1| 335|Homo sapiens densin hlg protein. 55 2e-07
AL445928-6|CAH72254.1| 339|Homo sapiens leucine rich repeat con... 55 2e-07
AL445928-5|CAH72253.1| 335|Homo sapiens leucine rich repeat con... 55 2e-07
AF169675-1|AAF28459.1| 674|Homo sapiens leucine-rich repeat tra... 55 2e-07
AB032989-1|BAA86477.1| 437|Homo sapiens KIAA1163 protein protein. 55 2e-07
AY899849-1|AAX85197.1| 709|Homo sapiens LGR7.2 protein. 54 3e-07
AK074723-1|BAC11161.1| 546|Homo sapiens protein ( Homo sapiens ... 54 3e-07
BC109118-1|AAI09119.1| 858|Homo sapiens TLR5 protein protein. 54 4e-07
BC018529-1|AAH18529.3| 683|Homo sapiens leucine-rich repeats an... 54 4e-07
BC007634-1|AAH07634.1| 580|Homo sapiens LRCH4 protein protein. 54 4e-07
AY324323-1|AAQ97218.1| 479|Homo sapiens leucine-rich repeat neu... 54 4e-07
AL929091-1|CAM28378.1| 858|Homo sapiens toll-like receptor 5 pr... 54 4e-07
AL365215-2|CAH73632.1| 224|Homo sapiens Ras suppressor protein ... 54 4e-07
AF053356-12|AAC78793.1| 832|Homo sapiens leucin rich neuronal p... 54 4e-07
AF051151-1|AAC34376.1| 858|Homo sapiens Toll/interleukin-1 rece... 54 4e-07
AB060695-1|BAB43955.1| 858|Homo sapiens Toll-like receptor 5 pr... 54 4e-07
BC063114-1|AAH63114.1| 384|Homo sapiens ASPN protein protein. 54 5e-07
BC040732-1|AAH40732.1| 269|Homo sapiens LRTM1 protein protein. 54 5e-07
BC032713-1|AAH32713.1| 1032|Homo sapiens toll-like receptor 9 pr... 54 5e-07
BC027475-1|AAH27475.2| 528|Homo sapiens LRFN4 protein protein. 54 5e-07
BC019687-1|AAH19687.1| 430|Homo sapiens LRRC4B protein protein. 54 5e-07
AY359085-1|AAQ89443.1| 1032|Homo sapiens TLR9 protein. 54 5e-07
AY358329-1|AAQ88695.1| 379|Homo sapiens ASPN protein. 54 5e-07
AY029191-1|AAK31800.1| 381|Homo sapiens periodontal ligament as... 54 5e-07
AL137848-6|CAI16697.1| 380|Homo sapiens asporin protein. 54 5e-07
AL137848-5|CAI16698.1| 243|Homo sapiens asporin protein. 54 5e-07
AK027359-1|BAB55060.1| 246|Homo sapiens protein ( Homo sapiens ... 54 5e-07
AF316824-1|AAK35161.1| 379|Homo sapiens asporin precursor protein. 54 5e-07
AF259263-1|AAF72190.1| 975|Homo sapiens toll-like receptor 9 fo... 54 5e-07
AF259262-1|AAF72189.1| 1032|Homo sapiens toll-like receptor 9 fo... 54 5e-07
AF245704-1|AAF78037.1| 1032|Homo sapiens toll-like receptor 9 pr... 54 5e-07
AB045180-1|BAB19259.1| 1032|Homo sapiens toll-like receptor 9 pr... 54 5e-07
BC022500-1|AAH22500.1| 557|Homo sapiens leucine-rich, glioma in... 53 7e-07
AY358885-1|AAQ89244.1| 557|Homo sapiens LGI1 protein. 53 7e-07
AY358289-1|AAQ88656.1| 696|Homo sapiens LLWI233 protein. 53 7e-07
AY324322-1|AAQ97217.1| 469|Homo sapiens leucine-rich repeat neu... 53 7e-07
AL589786-1|CAH70721.1| 612|Homo sapiens leucine-rich repeats an... 53 7e-07
AL445164-1|CAI43033.1| 612|Homo sapiens leucine-rich repeats an... 53 7e-07
AL358154-2|CAI14982.1| 557|Homo sapiens leucine-rich, glioma in... 53 7e-07
AL358154-1|CAI14981.1| 291|Homo sapiens leucine-rich, glioma in... 53 7e-07
AL355481-1|CAC37488.1| 696|Homo sapiens SLIT and NTRK-like fami... 53 7e-07
AL157396-3|CAH73838.1| 557|Homo sapiens leucine-rich, glioma in... 53 7e-07
AL157396-2|CAH73837.1| 291|Homo sapiens leucine-rich, glioma in... 53 7e-07
AL121878-2|CAI42077.1| 612|Homo sapiens leucine-rich repeats an... 53 7e-07
AK223177-1|BAD96897.1| 338|Homo sapiens lumican variant protein. 53 7e-07
AF473548-1|AAM22074.1| 291|Homo sapiens leucine-rich glioma ina... 53 7e-07
AF055636-1|AAC99316.1| 557|Homo sapiens leucine-rich glioma-ina... 53 7e-07
AB067497-1|BAB67803.1| 760|Homo sapiens KIAA1910 protein protein. 53 7e-07
AB031547-1|BAA95681.1| 623|Homo sapiens retina specific protein... 53 7e-07
BC051738-1|AAH51738.1| 696|Homo sapiens SLIT and NTRK-like fami... 53 9e-07
AF271734-1|AAP88018.1| 1601|Homo sapiens SCRIB1 variant N1 protein. 52 1e-06
D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein. 52 2e-06
BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein. 52 2e-06
AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated ant... 52 2e-06
BC125270-1|AAI25271.1| 669|Homo sapiens FSHR protein protein. 52 2e-06
BC101077-1|AAI01078.1| 1041|Homo sapiens toll-like receptor 8 pr... 52 2e-06
BC101076-1|AAI01077.1| 1041|Homo sapiens toll-like receptor 8 pr... 52 2e-06
BC101075-1|AAI01076.1| 1041|Homo sapiens toll-like receptor 8 pr... 52 2e-06
BC101074-1|AAI01075.1| 1041|Homo sapiens toll-like receptor 8 pr... 52 2e-06
BC035645-1|AAH35645.1| 1266|Homo sapiens Similar to RIKEN cDNA 3... 52 2e-06
BC030276-1|AAH30276.1| 529|Homo sapiens LOC220416 protein protein. 52 2e-06
AY358306-1|AAQ88673.1| 616|Homo sapiens GPR125 protein. 52 2e-06
AY358296-1|AAQ88663.1| 1041|Homo sapiens TLR8 protein. 52 2e-06
AL139801-5|CAM14704.1| 506|Homo sapiens similar to Leucine-rich... 52 2e-06
AL137141-1|CAI12166.2| 506|Homo sapiens similar to Leucine-rich... 52 2e-06
AF246971-1|AAF64061.1| 1059|Homo sapiens Toll-like receptor 8 pr... 52 2e-06
AF245703-1|AAF78036.1| 1041|Homo sapiens toll-like receptor 8 pr... 52 2e-06
J04599-1|AAA36009.1| 368|Homo sapiens protein ( Human hPGI mRNA... 51 3e-06
BT007323-1|AAP35987.1| 368|Homo sapiens biglycan protein. 51 3e-06
BC004244-1|AAH04244.1| 368|Homo sapiens biglycan protein. 51 3e-06
BC002416-1|AAH02416.1| 368|Homo sapiens biglycan protein. 51 3e-06
AK223302-1|BAD97022.1| 368|Homo sapiens biglycan preproprotein ... 51 3e-06
AY358112-1|AAQ88479.1| 802|Homo sapiens ITLT6413 protein. 51 4e-06
AL110276-1|CAB53711.1| 242|Homo sapiens hypothetical protein pr... 51 4e-06
Z24680-1|CAA80847.1| 662|Homo sapiens garp protein. 50 5e-06
M65085-1|AAA52477.1| 695|Homo sapiens follicle stimulating horm... 50 5e-06
BC070079-1|AAH70079.1| 662|Homo sapiens LRRC32 protein protein. 50 5e-06
AK222484-1|BAD96204.1| 368|Homo sapiens biglycan preproprotein ... 50 5e-06
CR457397-1|CAG33678.1| 708|Homo sapiens LRRN3 protein. 50 6e-06
BC142997-1|AAI42998.1| 524|Homo sapiens LGI3 protein protein. 50 6e-06
>M86826-1|AAA36047.1| 605|Homo sapiens insulin-like growth factor
binding protein complex protein.
Length = 605
Score = 108 bits (259), Expect = 2e-23
Identities = 62/188 (32%), Positives = 95/188 (50%), Gaps = 1/188 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFI 411
N YL +F GL ++E+ +S N +K VF LP L+ L LD + I + P F+
Sbjct: 204 NRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFL 263
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
LR L L+ N++ L G L L LS+NA+A L P F DL LE +
Sbjct: 264 GLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGH 323
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N ++ L + F GL L ++L +N++ + F G T++ ++LS N L P+ ++
Sbjct: 324 NRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFR 383
Query: 50 PLNQLHKL 27
L +LH L
Sbjct: 384 GLGKLHSL 391
Score = 85.0 bits (201), Expect = 2e-16
Identities = 57/190 (30%), Positives = 92/190 (48%), Gaps = 1/190 (0%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-F 414
RN R L F + + +SNN L++ +F L +L L L +S+ LP+ F
Sbjct: 131 RNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAF 190
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
LR L LA N+L L ++ G +L L LS NA+ + +F L L+ +D
Sbjct: 191 RGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLD 250
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
N + + F GL+ L + L +N+++ + +TF G +R L LS+N +A +
Sbjct: 251 RNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTF 310
Query: 53 SPLNQLHKLQ 24
L+ L +LQ
Sbjct: 311 KDLHFLEELQ 320
Score = 81.0 bits (191), Expect = 3e-15
Identities = 53/187 (28%), Positives = 87/187 (46%), Gaps = 1/187 (0%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE- 420
+ N+ L F+ L ++E+++ +N L E F L L L LD + ++E+
Sbjct: 297 LSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAG 356
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
F+ + + ++L+ N LR LP V RG +L SL L + + + P F L L
Sbjct: 357 AFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLF 416
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
+ N L + + GL L + L +N+++ + FQG + L LS NRLA P
Sbjct: 417 LKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPAD 476
Query: 59 LYSPLNQ 39
PL +
Sbjct: 477 ALGPLQR 483
Score = 80.2 bits (189), Expect = 5e-15
Identities = 56/171 (32%), Positives = 81/171 (47%), Gaps = 1/171 (0%)
Frame = -3
Query: 536 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRA 360
Q + + N ++ A F NL +L L L + L P+ + L L L RNQLR+
Sbjct: 77 QALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRS 136
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
L L SL LS N ++ L LF L +L + N L VLPD+ F GL +L
Sbjct: 137 LALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSL 196
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+ L N+++ + F G +R LDLS N L +++ L +L KL
Sbjct: 197 RELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKL 247
Score = 79.4 bits (187), Expect = 9e-15
Identities = 54/191 (28%), Positives = 91/191 (47%), Gaps = 1/191 (0%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ N L + F GL ++ +++S+N +L+ F +L L LQL + IR+L E
Sbjct: 273 LSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAER 332
Query: 416 -FISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
F L L+L NQL+ + G T + + LS N + L ++F L L +
Sbjct: 333 SFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLH 392
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
++G+ L + F+GL L + L++N + I + G + LDL+ N+L P
Sbjct: 393 LEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHR 452
Query: 59 LYSPLNQLHKL 27
L+ L +L L
Sbjct: 453 LFQGLGKLEYL 463
Score = 78.6 bits (185), Expect = 2e-14
Identities = 51/167 (30%), Positives = 83/167 (49%), Gaps = 1/167 (0%)
Frame = -3
Query: 572 LDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPL 396
L+ + GL+++ + + N +L F++ PAL +L L + + L + F L
Sbjct: 113 LEPQALLGLENLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSL 172
Query: 395 RTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 216
L+L N L LP + RG L L L+ N +A L P LF+ L L + N L+
Sbjct: 173 WDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRA 232
Query: 215 LPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLA 75
+ ++F L L + L N I+ ++ F G ++R LDLS+NR+A
Sbjct: 233 IKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVA 279
Score = 69.7 bits (163), Expect = 7e-12
Identities = 51/188 (27%), Positives = 82/188 (43%), Gaps = 1/188 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FI 411
N R L F GL ++ + + +N +K F L + + L + +R LPE+ F
Sbjct: 324 NRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFR 383
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L +L L + L + G + L L L N + + + L L +
Sbjct: 384 GLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTS 443
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N+L LP LF GL L + L N+++ + + LD+S+NRL P+SL +
Sbjct: 444 NQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLA 503
Query: 50 PLNQLHKL 27
PL +L L
Sbjct: 504 PLGRLRYL 511
Score = 68.9 bits (161), Expect = 1e-11
Identities = 45/147 (30%), Positives = 72/147 (48%), Gaps = 1/147 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N R L ++FRGL + + + + ++ F+ L LR L L + + + E+ +
Sbjct: 372 NCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLW 431
Query: 407 N-SPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
+ L L L NQL LP + +G +L L LS N +AEL + L+ +
Sbjct: 432 GLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSH 491
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKI 150
N L+ LP+SL + L L +SLRNN +
Sbjct: 492 NRLEALPNSLLAPLGRLRYLSLRNNSL 518
Score = 39.1 bits (87), Expect = 0.012
Identities = 30/114 (26%), Positives = 48/114 (42%), Gaps = 1/114 (0%)
Frame = -3
Query: 557 FRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSL 381
F GL ++ + + +N + ++E L L L L + + LP L L L
Sbjct: 406 FTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLL 465
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 219
+RN+L LP L + L +S+N + L L A L L + N L+
Sbjct: 466 SRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNNSLR 519
>AL031724-2|CAC36078.1| 605|Homo sapiens C447E6.2 (insulin-like
growth factor binding protein, acid labile subunit)
protein.
Length = 605
Score = 108 bits (259), Expect = 2e-23
Identities = 62/188 (32%), Positives = 95/188 (50%), Gaps = 1/188 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFI 411
N YL +F GL ++E+ +S N +K VF LP L+ L LD + I + P F+
Sbjct: 204 NRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFL 263
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
LR L L+ N++ L G L L LS+NA+A L P F DL LE +
Sbjct: 264 GLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGH 323
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N ++ L + F GL L ++L +N++ + F G T++ ++LS N L P+ ++
Sbjct: 324 NRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFR 383
Query: 50 PLNQLHKL 27
L +LH L
Sbjct: 384 GLGKLHSL 391
Score = 85.0 bits (201), Expect = 2e-16
Identities = 57/190 (30%), Positives = 92/190 (48%), Gaps = 1/190 (0%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-F 414
RN R L F + + +SNN L++ +F L +L L L +S+ LP+ F
Sbjct: 131 RNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAF 190
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
LR L LA N+L L ++ G +L L LS NA+ + +F L L+ +D
Sbjct: 191 RGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLD 250
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
N + + F GL+ L + L +N+++ + +TF G +R L LS+N +A +
Sbjct: 251 RNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTF 310
Query: 53 SPLNQLHKLQ 24
L+ L +LQ
Sbjct: 311 KDLHFLEELQ 320
Score = 81.0 bits (191), Expect = 3e-15
Identities = 53/187 (28%), Positives = 87/187 (46%), Gaps = 1/187 (0%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE- 420
+ N+ L F+ L ++E+++ +N L E F L L L LD + ++E+
Sbjct: 297 LSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAG 356
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
F+ + + ++L+ N LR LP V RG +L SL L + + + P F L L
Sbjct: 357 AFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLF 416
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
+ N L + + GL L + L +N+++ + FQG + L LS NRLA P
Sbjct: 417 LKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPAD 476
Query: 59 LYSPLNQ 39
PL +
Sbjct: 477 ALGPLQR 483
Score = 80.2 bits (189), Expect = 5e-15
Identities = 56/171 (32%), Positives = 81/171 (47%), Gaps = 1/171 (0%)
Frame = -3
Query: 536 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRA 360
Q + + N ++ A F NL +L L L + L P+ + L L L RNQLR+
Sbjct: 77 QALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRS 136
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
L L SL LS N ++ L LF L +L + N L VLPD+ F GL +L
Sbjct: 137 LALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSL 196
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+ L N+++ + F G +R LDLS N L +++ L +L KL
Sbjct: 197 RELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKL 247
Score = 79.4 bits (187), Expect = 9e-15
Identities = 54/191 (28%), Positives = 91/191 (47%), Gaps = 1/191 (0%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ N L + F GL ++ +++S+N +L+ F +L L LQL + IR+L E
Sbjct: 273 LSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAER 332
Query: 416 -FISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
F L L+L NQL+ + G T + + LS N + L ++F L L +
Sbjct: 333 SFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLH 392
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
++G+ L + F+GL L + L++N + I + G + LDL+ N+L P
Sbjct: 393 LEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHR 452
Query: 59 LYSPLNQLHKL 27
L+ L +L L
Sbjct: 453 LFQGLGKLEYL 463
Score = 78.6 bits (185), Expect = 2e-14
Identities = 51/167 (30%), Positives = 83/167 (49%), Gaps = 1/167 (0%)
Frame = -3
Query: 572 LDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPL 396
L+ + GL+++ + + N +L F++ PAL +L L + + L + F L
Sbjct: 113 LEPQALLGLENLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSL 172
Query: 395 RTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 216
L+L N L LP + RG L L L+ N +A L P LF+ L L + N L+
Sbjct: 173 WDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRA 232
Query: 215 LPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLA 75
+ ++F L L + L N I+ ++ F G ++R LDLS+NR+A
Sbjct: 233 IKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVA 279
Score = 69.7 bits (163), Expect = 7e-12
Identities = 51/188 (27%), Positives = 82/188 (43%), Gaps = 1/188 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FI 411
N R L F GL ++ + + +N +K F L + + L + +R LPE+ F
Sbjct: 324 NRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFR 383
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L +L L + L + G + L L L N + + + L L +
Sbjct: 384 GLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTS 443
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N+L LP LF GL L + L N+++ + + LD+S+NRL P+SL +
Sbjct: 444 NQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLA 503
Query: 50 PLNQLHKL 27
PL +L L
Sbjct: 504 PLGRLRYL 511
Score = 68.9 bits (161), Expect = 1e-11
Identities = 45/147 (30%), Positives = 72/147 (48%), Gaps = 1/147 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N R L ++FRGL + + + + ++ F+ L LR L L + + + E+ +
Sbjct: 372 NCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLW 431
Query: 407 N-SPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
+ L L L NQL LP + +G +L L LS N +AEL + L+ +
Sbjct: 432 GLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSH 491
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKI 150
N L+ LP+SL + L L +SLRNN +
Sbjct: 492 NRLEALPNSLLAPLGRLRYLSLRNNSL 518
Score = 39.1 bits (87), Expect = 0.012
Identities = 30/114 (26%), Positives = 48/114 (42%), Gaps = 1/114 (0%)
Frame = -3
Query: 557 FRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSL 381
F GL ++ + + +N + ++E L L L L + + LP L L L
Sbjct: 406 FTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLL 465
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 219
+RN+L LP L + L +S+N + L L A L L + N L+
Sbjct: 466 SRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNNSLR 519
>AF192554-1|AAF06774.1| 605|Homo sapiens acid-labile subunit
protein.
Length = 605
Score = 108 bits (259), Expect = 2e-23
Identities = 62/188 (32%), Positives = 95/188 (50%), Gaps = 1/188 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFI 411
N YL +F GL ++E+ +S N +K VF LP L+ L LD + I + P F+
Sbjct: 204 NRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFL 263
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
LR L L+ N++ L G L L LS+NA+A L P F DL LE +
Sbjct: 264 GLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGH 323
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N ++ L + F GL L ++L +N++ + F G T++ ++LS N L P+ ++
Sbjct: 324 NRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFR 383
Query: 50 PLNQLHKL 27
L +LH L
Sbjct: 384 GLGKLHSL 391
Score = 85.0 bits (201), Expect = 2e-16
Identities = 57/190 (30%), Positives = 92/190 (48%), Gaps = 1/190 (0%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-F 414
RN R L F + + +SNN L++ +F L +L L L +S+ LP+ F
Sbjct: 131 RNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAF 190
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
LR L LA N+L L ++ G +L L LS NA+ + +F L L+ +D
Sbjct: 191 RGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLD 250
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
N + + F GL+ L + L +N+++ + +TF G +R L LS+N +A +
Sbjct: 251 RNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTF 310
Query: 53 SPLNQLHKLQ 24
L+ L +LQ
Sbjct: 311 KDLHFLEELQ 320
Score = 81.0 bits (191), Expect = 3e-15
Identities = 53/187 (28%), Positives = 87/187 (46%), Gaps = 1/187 (0%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE- 420
+ N+ L F+ L ++E+++ +N L E F L L L LD + ++E+
Sbjct: 297 LSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAG 356
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
F+ + + ++L+ N LR LP V RG +L SL L + + + P F L L
Sbjct: 357 AFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLF 416
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
+ N L + + GL L + L +N+++ + FQG + L LS NRLA P
Sbjct: 417 LKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPAD 476
Query: 59 LYSPLNQ 39
PL +
Sbjct: 477 ALGPLQR 483
Score = 80.2 bits (189), Expect = 5e-15
Identities = 56/171 (32%), Positives = 81/171 (47%), Gaps = 1/171 (0%)
Frame = -3
Query: 536 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRA 360
Q + + N ++ A F NL +L L L + L P+ + L L L RNQLR+
Sbjct: 77 QALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRS 136
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
L L SL LS N ++ L LF L +L + N L VLPD+ F GL +L
Sbjct: 137 LALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSL 196
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+ L N+++ + F G +R LDLS N L +++ L +L KL
Sbjct: 197 RELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKL 247
Score = 79.4 bits (187), Expect = 9e-15
Identities = 54/191 (28%), Positives = 91/191 (47%), Gaps = 1/191 (0%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ N L + F GL ++ +++S+N +L+ F +L L LQL + IR+L E
Sbjct: 273 LSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAER 332
Query: 416 -FISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
F L L+L NQL+ + G T + + LS N + L ++F L L +
Sbjct: 333 SFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLH 392
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
++G+ L + F+GL L + L++N + I + G + LDL+ N+L P
Sbjct: 393 LEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHR 452
Query: 59 LYSPLNQLHKL 27
L+ L +L L
Sbjct: 453 LFQGLGKLEYL 463
Score = 78.6 bits (185), Expect = 2e-14
Identities = 51/167 (30%), Positives = 83/167 (49%), Gaps = 1/167 (0%)
Frame = -3
Query: 572 LDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPL 396
L+ + GL+++ + + N +L F++ PAL +L L + + L + F L
Sbjct: 113 LEPQALLGLENLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSL 172
Query: 395 RTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 216
L+L N L LP + RG L L L+ N +A L P LF+ L L + N L+
Sbjct: 173 WDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRA 232
Query: 215 LPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLA 75
+ ++F L L + L N I+ ++ F G ++R LDLS+NR+A
Sbjct: 233 IKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVA 279
Score = 69.7 bits (163), Expect = 7e-12
Identities = 51/188 (27%), Positives = 82/188 (43%), Gaps = 1/188 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FI 411
N R L F GL ++ + + +N +K F L + + L + +R LPE+ F
Sbjct: 324 NRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFR 383
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L +L L + L + G + L L L N + + + L L +
Sbjct: 384 GLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTS 443
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N+L LP LF GL L + L N+++ + + LD+S+NRL P+SL +
Sbjct: 444 NQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLA 503
Query: 50 PLNQLHKL 27
PL +L L
Sbjct: 504 PLGRLRYL 511
Score = 68.9 bits (161), Expect = 1e-11
Identities = 45/147 (30%), Positives = 72/147 (48%), Gaps = 1/147 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N R L ++FRGL + + + + ++ F+ L LR L L + + + E+ +
Sbjct: 372 NCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLW 431
Query: 407 N-SPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
+ L L L NQL LP + +G +L L LS N +AEL + L+ +
Sbjct: 432 GLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSH 491
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKI 150
N L+ LP+SL + L L +SLRNN +
Sbjct: 492 NRLEALPNSLLAPLGRLRYLSLRNNSL 518
Score = 39.1 bits (87), Expect = 0.012
Identities = 30/114 (26%), Positives = 48/114 (42%), Gaps = 1/114 (0%)
Frame = -3
Query: 557 FRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSL 381
F GL ++ + + +N + ++E L L L L + + LP L L L
Sbjct: 406 FTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLL 465
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 219
+RN+L LP L + L +S+N + L L A L L + N L+
Sbjct: 466 SRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNNSLR 519
>BC025681-1|AAH25681.1| 605|Homo sapiens insulin-like growth factor
binding protein, acid labile subunit protein.
Length = 605
Score = 107 bits (257), Expect = 3e-23
Identities = 62/188 (32%), Positives = 95/188 (50%), Gaps = 1/188 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFI 411
N YL +F GL ++E+ +S N +K VF LP L+ L LD + I + P F+
Sbjct: 204 NRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFL 263
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
LR L L+ N++ L G L L LS+NA+A L P F DL LE +
Sbjct: 264 GLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGH 323
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N ++ L + F GL L ++L +N++ + F G T++ ++LS N L P+ ++
Sbjct: 324 NRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNMAVMNLSGNCLRNLPEQVFR 383
Query: 50 PLNQLHKL 27
L +LH L
Sbjct: 384 GLGKLHSL 391
Score = 85.0 bits (201), Expect = 2e-16
Identities = 57/190 (30%), Positives = 92/190 (48%), Gaps = 1/190 (0%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-F 414
RN R L F + + +SNN L++ +F L +L L L +S+ LP+ F
Sbjct: 131 RNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAF 190
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
LR L LA N+L L ++ G +L L LS NA+ + +F L L+ +D
Sbjct: 191 RGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLD 250
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
N + + F GL+ L + L +N+++ + +TF G +R L LS+N +A +
Sbjct: 251 RNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTF 310
Query: 53 SPLNQLHKLQ 24
L+ L +LQ
Sbjct: 311 KDLHFLEELQ 320
Score = 81.4 bits (192), Expect = 2e-15
Identities = 53/187 (28%), Positives = 87/187 (46%), Gaps = 1/187 (0%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE- 420
+ N+ L F+ L ++E+++ +N L E F L L L LD + ++E+
Sbjct: 297 LSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAG 356
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
F+ + + ++L+ N LR LP V RG +L SL L + + + P F L L
Sbjct: 357 AFLGLTNMAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLF 416
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
+ N L + + GL L + L +N+++ + FQG + L LS NRLA P
Sbjct: 417 LKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPAD 476
Query: 59 LYSPLNQ 39
PL +
Sbjct: 477 ALGPLQR 483
Score = 80.2 bits (189), Expect = 5e-15
Identities = 56/171 (32%), Positives = 81/171 (47%), Gaps = 1/171 (0%)
Frame = -3
Query: 536 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRA 360
Q + + N ++ A F NL +L L L + L P+ + L L L RNQLR+
Sbjct: 77 QALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRS 136
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
L L SL LS N ++ L LF L +L + N L VLPD+ F GL +L
Sbjct: 137 LALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSL 196
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+ L N+++ + F G +R LDLS N L +++ L +L KL
Sbjct: 197 RELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKL 247
Score = 79.8 bits (188), Expect = 7e-15
Identities = 54/191 (28%), Positives = 91/191 (47%), Gaps = 1/191 (0%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ N L + F GL ++ +++S+N +L+ F +L L LQL + IR+L E
Sbjct: 273 LSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAER 332
Query: 416 -FISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
F L L+L NQL+ + G T + + LS N + L ++F L L +
Sbjct: 333 SFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNMAVMNLSGNCLRNLPEQVFRGLGKLHSLH 392
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
++G+ L + F+GL L + L++N + I + G + LDL+ N+L P
Sbjct: 393 LEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHR 452
Query: 59 LYSPLNQLHKL 27
L+ L +L L
Sbjct: 453 LFQGLGKLEYL 463
Score = 78.6 bits (185), Expect = 2e-14
Identities = 51/167 (30%), Positives = 83/167 (49%), Gaps = 1/167 (0%)
Frame = -3
Query: 572 LDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPL 396
L+ + GL+++ + + N +L F++ PAL +L L + + L + F L
Sbjct: 113 LEPQALLGLENLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSL 172
Query: 395 RTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 216
L+L N L LP + RG L L L+ N +A L P LF+ L L + N L+
Sbjct: 173 WDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRA 232
Query: 215 LPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLA 75
+ ++F L L + L N I+ ++ F G ++R LDLS+NR+A
Sbjct: 233 IKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVA 279
Score = 70.1 bits (164), Expect = 6e-12
Identities = 51/188 (27%), Positives = 82/188 (43%), Gaps = 1/188 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FI 411
N R L F GL ++ + + +N +K F L + + L + +R LPE+ F
Sbjct: 324 NRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNMAVMNLSGNCLRNLPEQVFR 383
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L +L L + L + G + L L L N + + + L L +
Sbjct: 384 GLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTS 443
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N+L LP LF GL L + L N+++ + + LD+S+NRL P+SL +
Sbjct: 444 NQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLA 503
Query: 50 PLNQLHKL 27
PL +L L
Sbjct: 504 PLGRLRYL 511
Score = 68.9 bits (161), Expect = 1e-11
Identities = 45/147 (30%), Positives = 72/147 (48%), Gaps = 1/147 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N R L ++FRGL + + + + ++ F+ L LR L L + + + E+ +
Sbjct: 372 NCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLW 431
Query: 407 N-SPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
+ L L L NQL LP + +G +L L LS N +AEL + L+ +
Sbjct: 432 GLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSH 491
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKI 150
N L+ LP+SL + L L +SLRNN +
Sbjct: 492 NRLEALPNSLLAPLGRLRYLSLRNNSL 518
Score = 39.1 bits (87), Expect = 0.012
Identities = 30/114 (26%), Positives = 48/114 (42%), Gaps = 1/114 (0%)
Frame = -3
Query: 557 FRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSL 381
F GL ++ + + +N + ++E L L L L + + LP L L L
Sbjct: 406 FTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLL 465
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 219
+RN+L LP L + L +S+N + L L A L L + N L+
Sbjct: 466 SRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNNSLR 519
>J05158-1|AAA51921.2| 545|Homo sapiens carboxypeptidase N precursor
protein.
Length = 545
Score = 100 bits (239), Expect = 4e-21
Identities = 61/188 (32%), Positives = 99/188 (52%), Gaps = 1/188 (0%)
Frame = -3
Query: 563 EIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTL 387
+ F GL +++++++ + L L +FSNL +L L L+ + + LPE + + L +L
Sbjct: 91 DAFGGLPRLEDLEVTGSSFLNLSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESL 150
Query: 386 SLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPD 207
L NQL+ALPR + + T L +L L+ N +A+L ELF L +L+T + N L LP
Sbjct: 151 HLQGNQLQALPRRLFQPLTHLKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQ 210
Query: 206 SLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+F L +L + L +N IS + F + L L N + P S+++ L L
Sbjct: 211 GVFGKLGSLQELFLDSNNISELPPQVFSQLFCLERLWLQRNAITHLPLSIFASLG---NL 267
Query: 26 QTLTLAWN 3
L+L WN
Sbjct: 268 TFLSLQWN 275
Score = 92.3 bits (219), Expect = 1e-18
Identities = 59/192 (30%), Positives = 96/192 (50%), Gaps = 1/192 (0%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE 420
T+ N L +F+ L ++ + + N L +F L L+TL L + + +LPE
Sbjct: 127 TLNFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHLKTLNLAQNLLAQLPE 186
Query: 419 E-FISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETF 243
E F + L+TL L+ N L LP+ V L L L N ++EL P++F+ L LE
Sbjct: 187 ELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCLERL 246
Query: 242 VMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPD 63
+ N + LP S+F+ L NLT +SL+ N + V+ F + L L++N+L +
Sbjct: 247 WLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLETVAE 306
Query: 62 SLYSPLNQLHKL 27
++ L+ L L
Sbjct: 307 GTFAHLSNLRSL 318
Score = 92.3 bits (219), Expect = 1e-18
Identities = 57/188 (30%), Positives = 95/188 (50%), Gaps = 1/188 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N + L +F+ L H++ + ++ N+ L E +F L +L+TL+L +++ LP+
Sbjct: 155 NQLQALPRRLFQPLTHLKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFG 214
Query: 407 N-SPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L+ L L N + LP V L L L NA+ L +FA L L +
Sbjct: 215 KLGSLQELFLDSNNISELPPQVFSQLFCLERLWLQRNAITHLPLSIFASLGNLTFLSLQW 274
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N L+VLP LF+ L +SL +N++ ++ TF +++R+L LSYN + P ++
Sbjct: 275 NMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFR 334
Query: 50 PLNQLHKL 27
L +L KL
Sbjct: 335 DLEELVKL 342
Score = 87.4 bits (207), Expect = 3e-17
Identities = 62/199 (31%), Positives = 96/199 (48%), Gaps = 1/199 (0%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ +N L E+F L +Q +K+SNN L + VF L +L+ L LD ++I ELP +
Sbjct: 176 LAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQ 235
Query: 416 FISNS-PLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
S L L L RN + LP S+ LT L+L +N + L LFA L
Sbjct: 236 VFSQLFCLERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLS 295
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
+ N+L+ + + F+ L NL ++ L N I+ + F+ + L L N L +
Sbjct: 296 LTHNQLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPA 355
Query: 59 LYSPLNQLHKLQTLTLAWN 3
L+ L KL+ L+L+ N
Sbjct: 356 LF---QNLSKLELLSLSKN 371
Score = 79.0 bits (186), Expect = 1e-14
Identities = 50/160 (31%), Positives = 79/160 (49%), Gaps = 1/160 (0%)
Frame = -3
Query: 503 TLKEAVFSNLPAL-RTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQ 327
TL+ F + P L + + L+ + P+ F L L + + L ++ T
Sbjct: 63 TLETRAFGSNPNLTKVVFLNTQLCQFRPDAFGGLPRLEDLEVTGSSFLNLSTNIFSNLTS 122
Query: 326 LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKIS 147
L LTL++N + L LF L ALE+ + GN+LQ LP LF L +L T++L N ++
Sbjct: 123 LGKLTLNFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHLKTLNLAQNLLA 182
Query: 146 VISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+ F TS++TL LS N L+ P ++ L L +L
Sbjct: 183 QLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQEL 222
Score = 74.5 bits (175), Expect = 3e-13
Identities = 49/169 (28%), Positives = 78/169 (46%), Gaps = 1/169 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N+ L ++F L ++ + + N L ++F++L L L L + +R LP +
Sbjct: 227 NNISELPPQVFSQLFCLERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFA 286
Query: 407 NSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
++P L LSL NQL + + L SL LSYNA+ L +F DL L +
Sbjct: 287 HTPCLVGLSLTHNQLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGS 346
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
N L L +LF L L +SL N+++ + F ++ L L N
Sbjct: 347 NNLTALHPALFQNLSKLELLSLSKNQLTTLPEGIFDTNYNLFNLALHGN 395
>BC031569-1|AAH31569.2| 545|Homo sapiens carboxypeptidase N,
polypeptide 2 protein.
Length = 545
Score = 100 bits (239), Expect = 4e-21
Identities = 61/188 (32%), Positives = 99/188 (52%), Gaps = 1/188 (0%)
Frame = -3
Query: 563 EIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTL 387
+ F GL +++++++ + L L +FSNL +L L L+ + + LPE + + L +L
Sbjct: 91 DAFGGLPRLEDLEVTGSSFLNLSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESL 150
Query: 386 SLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPD 207
L NQL+ALPR + + T L +L L+ N +A+L ELF L +L+T + N L LP
Sbjct: 151 HLQGNQLQALPRRLFQPLTHLKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQ 210
Query: 206 SLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+F L +L + L +N IS + F + L L N + P S+++ L L
Sbjct: 211 GVFGKLGSLQELFLDSNNISELPPQVFSQLFCLERLWLQRNAITHLPLSIFASLG---NL 267
Query: 26 QTLTLAWN 3
L+L WN
Sbjct: 268 TFLSLQWN 275
Score = 92.3 bits (219), Expect = 1e-18
Identities = 59/192 (30%), Positives = 96/192 (50%), Gaps = 1/192 (0%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE 420
T+ N L +F+ L ++ + + N L +F L L+TL L + + +LPE
Sbjct: 127 TLNFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHLKTLNLAQNLLAQLPE 186
Query: 419 E-FISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETF 243
E F + L+TL L+ N L LP+ V L L L N ++EL P++F+ L LE
Sbjct: 187 ELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCLERL 246
Query: 242 VMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPD 63
+ N + LP S+F+ L NLT +SL+ N + V+ F + L L++N+L +
Sbjct: 247 WLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLETVAE 306
Query: 62 SLYSPLNQLHKL 27
++ L+ L L
Sbjct: 307 GTFAHLSNLRSL 318
Score = 92.3 bits (219), Expect = 1e-18
Identities = 57/188 (30%), Positives = 95/188 (50%), Gaps = 1/188 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N + L +F+ L H++ + ++ N+ L E +F L +L+TL+L +++ LP+
Sbjct: 155 NQLQALPRRLFQPLTHLKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFG 214
Query: 407 N-SPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L+ L L N + LP V L L L NA+ L +FA L L +
Sbjct: 215 KLGSLQELFLDSNNISELPPQVFSQLFCLERLWLQRNAITHLPLSIFASLGNLTFLSLQW 274
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N L+VLP LF+ L +SL +N++ ++ TF +++R+L LSYN + P ++
Sbjct: 275 NMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFR 334
Query: 50 PLNQLHKL 27
L +L KL
Sbjct: 335 DLEELVKL 342
Score = 87.4 bits (207), Expect = 3e-17
Identities = 62/199 (31%), Positives = 96/199 (48%), Gaps = 1/199 (0%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ +N L E+F L +Q +K+SNN L + VF L +L+ L LD ++I ELP +
Sbjct: 176 LAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQ 235
Query: 416 FISNS-PLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
S L L L RN + LP S+ LT L+L +N + L LFA L
Sbjct: 236 VFSQLFCLERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLS 295
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
+ N+L+ + + F+ L NL ++ L N I+ + F+ + L L N L +
Sbjct: 296 LTHNQLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPA 355
Query: 59 LYSPLNQLHKLQTLTLAWN 3
L+ L KL+ L+L+ N
Sbjct: 356 LF---QNLSKLELLSLSKN 371
Score = 79.0 bits (186), Expect = 1e-14
Identities = 50/160 (31%), Positives = 79/160 (49%), Gaps = 1/160 (0%)
Frame = -3
Query: 503 TLKEAVFSNLPAL-RTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQ 327
TL+ F + P L + + L+ + P+ F L L + + L ++ T
Sbjct: 63 TLETRAFGSNPNLTKVVFLNTQLCQFRPDAFGGLPRLEDLEVTGSSFLNLSTNIFSNLTS 122
Query: 326 LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKIS 147
L LTL++N + L LF L ALE+ + GN+LQ LP LF L +L T++L N ++
Sbjct: 123 LGKLTLNFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHLKTLNLAQNLLA 182
Query: 146 VISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+ F TS++TL LS N L+ P ++ L L +L
Sbjct: 183 QLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQEL 222
Score = 74.5 bits (175), Expect = 3e-13
Identities = 49/169 (28%), Positives = 78/169 (46%), Gaps = 1/169 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N+ L ++F L ++ + + N L ++F++L L L L + +R LP +
Sbjct: 227 NNISELPPQVFSQLFCLERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFA 286
Query: 407 NSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
++P L LSL NQL + + L SL LSYNA+ L +F DL L +
Sbjct: 287 HTPCLVGLSLTHNQLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGS 346
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
N L L +LF L L +SL N+++ + F ++ L L N
Sbjct: 347 NNLTALHPALFQNLSKLELLSLSKNQLTTLPEGIFDTNYNLFNLALHGN 395
>BC042334-1|AAH42334.2| 545|Homo sapiens carboxypeptidase N,
polypeptide 2 protein.
Length = 545
Score = 98.7 bits (235), Expect = 1e-20
Identities = 60/188 (31%), Positives = 99/188 (52%), Gaps = 1/188 (0%)
Frame = -3
Query: 563 EIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTL 387
+ F GL +++++++ + L L +FSNL +L L L+ + + LPE + + L +L
Sbjct: 91 DAFGGLPRLEDLEVTGSSFLNLSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESL 150
Query: 386 SLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPD 207
L N+L+ALPR + + T L +L L+ N +A+L ELF L +L+T + N L LP
Sbjct: 151 HLQGNRLQALPRRLFQPLTHLKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQ 210
Query: 206 SLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+F L +L + L +N IS + F + L L N + P S+++ L L
Sbjct: 211 GVFGKLGSLQELFLDSNNISELPPQVFSQLFCLERLWLQRNAITHLPLSIFASLG---NL 267
Query: 26 QTLTLAWN 3
L+L WN
Sbjct: 268 TFLSLQWN 275
Score = 91.9 bits (218), Expect = 2e-18
Identities = 59/192 (30%), Positives = 96/192 (50%), Gaps = 1/192 (0%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE 420
T+ N L +F+ L ++ + + N L +F L L+TL L + + +LPE
Sbjct: 127 TLNFNMLEALPEGLFQHLAALESLHLQGNRLQALPRRLFQPLTHLKTLNLAQNLLAQLPE 186
Query: 419 E-FISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETF 243
E F + L+TL L+ N L LP+ V L L L N ++EL P++F+ L LE
Sbjct: 187 ELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCLERL 246
Query: 242 VMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPD 63
+ N + LP S+F+ L NLT +SL+ N + V+ F + L L++N+L +
Sbjct: 247 WLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLETVAE 306
Query: 62 SLYSPLNQLHKL 27
++ L+ L L
Sbjct: 307 GTFAHLSNLRSL 318
Score = 91.9 bits (218), Expect = 2e-18
Identities = 57/188 (30%), Positives = 95/188 (50%), Gaps = 1/188 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N + L +F+ L H++ + ++ N+ L E +F L +L+TL+L +++ LP+
Sbjct: 155 NRLQALPRRLFQPLTHLKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFG 214
Query: 407 N-SPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L+ L L N + LP V L L L NA+ L +FA L L +
Sbjct: 215 KLGSLQELFLDSNNISELPPQVFSQLFCLERLWLQRNAITHLPLSIFASLGNLTFLSLQW 274
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N L+VLP LF+ L +SL +N++ ++ TF +++R+L LSYN + P ++
Sbjct: 275 NMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFR 334
Query: 50 PLNQLHKL 27
L +L KL
Sbjct: 335 DLEELVKL 342
Score = 87.4 bits (207), Expect = 3e-17
Identities = 62/199 (31%), Positives = 96/199 (48%), Gaps = 1/199 (0%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ +N L E+F L +Q +K+SNN L + VF L +L+ L LD ++I ELP +
Sbjct: 176 LAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQ 235
Query: 416 FISNS-PLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
S L L L RN + LP S+ LT L+L +N + L LFA L
Sbjct: 236 VFSQLFCLERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLS 295
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
+ N+L+ + + F+ L NL ++ L N I+ + F+ + L L N L +
Sbjct: 296 LTHNQLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPA 355
Query: 59 LYSPLNQLHKLQTLTLAWN 3
L+ L KL+ L+L+ N
Sbjct: 356 LF---QNLSKLELLSLSKN 371
Score = 78.2 bits (184), Expect = 2e-14
Identities = 50/160 (31%), Positives = 78/160 (48%), Gaps = 1/160 (0%)
Frame = -3
Query: 503 TLKEAVFSNLPAL-RTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQ 327
TL+ F + P L + + L+ + P+ F L L + + L ++ T
Sbjct: 63 TLETRAFGSNPNLTKVVFLNTQLCQFRPDAFGGLPRLEDLEVTGSSFLNLSTNIFSNLTS 122
Query: 326 LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKIS 147
L LTL++N + L LF L ALE+ + GN LQ LP LF L +L T++L N ++
Sbjct: 123 LGKLTLNFNMLEALPEGLFQHLAALESLHLQGNRLQALPRRLFQPLTHLKTLNLAQNLLA 182
Query: 146 VISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+ F TS++TL LS N L+ P ++ L L +L
Sbjct: 183 QLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQEL 222
Score = 74.5 bits (175), Expect = 3e-13
Identities = 49/169 (28%), Positives = 78/169 (46%), Gaps = 1/169 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N+ L ++F L ++ + + N L ++F++L L L L + +R LP +
Sbjct: 227 NNISELPPQVFSQLFCLERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFA 286
Query: 407 NSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
++P L LSL NQL + + L SL LSYNA+ L +F DL L +
Sbjct: 287 HTPCLVGLSLTHNQLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGS 346
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
N L L +LF L L +SL N+++ + F ++ L L N
Sbjct: 347 NNLTALHPALFQNLSKLELLSLSKNQLTTLPEGIFDTNYNLFNLALHGN 395
>BC033039-1|AAH33039.1| 927|Homo sapiens LGR4 protein protein.
Length = 927
Score = 98.3 bits (234), Expect = 2e-20
Identities = 62/192 (32%), Positives = 97/192 (50%), Gaps = 1/192 (0%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE 420
T+ N + + SE RGL +Q +++ N ++ E F L LR L LD +S+ E+P
Sbjct: 87 TLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPV 146
Query: 419 EFISNSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETF 243
+SN P L+ L+LA N++ ++P + L L L N + L+ F L LET
Sbjct: 147 HHLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETL 206
Query: 242 VMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPD 63
++ N L P ++ L +L + +N ISVI F G +RT+ L N L+F +
Sbjct: 207 DLNYNNLGEFPQAI-KALPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGN 265
Query: 62 SLYSPLNQLHKL 27
S + L+ LH L
Sbjct: 266 SAFHNLSDLHSL 277
Score = 84.6 bits (200), Expect = 2e-16
Identities = 47/161 (29%), Positives = 82/161 (50%), Gaps = 1/161 (0%)
Frame = -3
Query: 536 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRA 360
Q ++++ N + S L L+ L L + ++ +P E I S L++L L N + +
Sbjct: 60 QALQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITS 119
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
+P G QL L L N++ E+ ++L L+ + N++ +PD F+ L +L
Sbjct: 120 VPEDSFEGLVQLRHLWLDDNSLTEVPVHHLSNLPTLQALTLALNKISSIPDFAFTNLSSL 179
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
+ L NNKI +S + F G ++ TLDL+YN L P ++
Sbjct: 180 VVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQAI 220
Score = 68.5 bits (160), Expect = 2e-11
Identities = 49/184 (26%), Positives = 83/184 (45%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
NS + F G ++ I + +N + + F NL L +L + +S+ +
Sbjct: 234 NSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFPNLTG 293
Query: 407 NSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 228
L +L+L ++ ++P ++ + Q L +L LSYN + +L F ALE + N
Sbjct: 294 TVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLPS--FNGCHALEEISLQRN 351
Query: 227 ELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSP 48
++ + + F GL +L + L N I I F I LD+S+N L P +
Sbjct: 352 QIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFPTEGLNG 411
Query: 47 LNQL 36
LNQL
Sbjct: 412 LNQL 415
Score = 62.9 bits (146), Expect = 8e-10
Identities = 48/156 (30%), Positives = 71/156 (45%)
Frame = -3
Query: 470 ALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVA 291
AL+ DLS I P+ L+ L+L NQL+ +P +RG + L SL L N +
Sbjct: 61 ALQLAGNDLSFIH--PKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHIT 118
Query: 290 ELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATS 111
+ + F L L +D N L +P S L L ++L NKIS I F +S
Sbjct: 119 SVPEDSFEGLVQLRHLWLDDNSLTEVPVHHLSNLPTLQALTLALNKISSIPDFAFTNLSS 178
Query: 110 IRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
+ L L N++ + L+ L+TL L +N
Sbjct: 179 LVVLHLHNNKIRSLSQHCFDGLD---NLETLDLNYN 211
Score = 58.4 bits (135), Expect = 2e-08
Identities = 32/120 (26%), Positives = 60/120 (50%)
Frame = -3
Query: 395 RTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 216
+ L LA N L + L G +L LTL N + + E L AL++ +D N +
Sbjct: 60 QALQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITS 119
Query: 215 LPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQL 36
+P+ F GL L + L +N ++ + ++ +++ L L+ N+++ PD ++ L+ L
Sbjct: 120 VPEDSFEGLVQLRHLWLDDNSLTEVPVHHLSNLPTLQALTLALNKISSIPDFAFTNLSSL 179
>AB209743-1|BAD92980.1| 1032|Homo sapiens Leucine-rich
repeat-containing G protein-coupled receptor 4 precursor
variant protein.
Length = 1032
Score = 97.1 bits (231), Expect = 4e-20
Identities = 62/192 (32%), Positives = 97/192 (50%), Gaps = 1/192 (0%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE 420
T+ N + + SE RGL +Q +++ N ++ E F L LR L LD +S+ E+P
Sbjct: 192 TLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPV 251
Query: 419 EFISNSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETF 243
+SN P L+ L+LA N++ ++P + L L L N + L+ F L LET
Sbjct: 252 HPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETL 311
Query: 242 VMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPD 63
++ N L P ++ L +L + +N ISVI F G +RT+ L N L+F +
Sbjct: 312 DLNYNNLGEFPQAI-KALPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGN 370
Query: 62 SLYSPLNQLHKL 27
S + L+ LH L
Sbjct: 371 SAFHNLSDLHSL 382
Score = 92.7 bits (220), Expect = 9e-19
Identities = 50/178 (28%), Positives = 90/178 (50%), Gaps = 1/178 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N+ L + F+ ++E++++ N + S L L+ L L + ++ +P E I
Sbjct: 148 NNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIR 207
Query: 407 N-SPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
S L++L L N + ++P G QL L L N++ E+ ++L L+ +
Sbjct: 208 GLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLAL 267
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
N++ +PD F+ L +L + L NNKI +S + F G ++ TLDL+YN L P ++
Sbjct: 268 NKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQAI 325
Score = 75.4 bits (177), Expect = 1e-13
Identities = 59/181 (32%), Positives = 82/181 (45%), Gaps = 3/181 (1%)
Frame = -3
Query: 536 QEIKISNNVPLTLKEAVFSNLPALRTLQL---DLSSIRELPEEFISNSPLRTLSLARNQL 366
Q + IS N L E F N P L LQL DLS I P+ L+ L+L NQL
Sbjct: 141 QALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIH--PKALSGLKELKVLTLQNNQL 198
Query: 365 RALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLR 186
+ +P +RG + L SL L N + + + F L L +D N L +P S L
Sbjct: 199 KTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLP 258
Query: 185 NLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAW 6
L ++L NKIS I F +S+ L L N++ + L+ L+TL L +
Sbjct: 259 TLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLD---NLETLDLNY 315
Query: 5 N 3
N
Sbjct: 316 N 316
Score = 68.5 bits (160), Expect = 2e-11
Identities = 49/184 (26%), Positives = 83/184 (45%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
NS + F G ++ I + +N + + F NL L +L + +S+ +
Sbjct: 339 NSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFPNLTG 398
Query: 407 NSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 228
L +L+L ++ ++P ++ + Q L +L LSYN + +L F ALE + N
Sbjct: 399 TVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLPS--FNGCHALEEISLQRN 456
Query: 227 ELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSP 48
++ + + F GL +L + L N I I F I LD+S+N L P +
Sbjct: 457 QIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFPTEGLNG 516
Query: 47 LNQL 36
LNQL
Sbjct: 517 LNQL 520
>BC101065-1|AAI01066.1| 581|Homo sapiens LRRC15 protein protein.
Length = 581
Score = 95.1 bits (226), Expect = 2e-19
Identities = 60/189 (31%), Positives = 93/189 (49%), Gaps = 1/189 (0%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEF 414
+NS ++ +F+ L ++Q +++ N + F L L+ L L + I L P F
Sbjct: 182 KNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLF 241
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
+N L+ L L+ N + LP SV QL LTL N++ EL+P +F + L +
Sbjct: 242 HNNHNLQRLYLSNNHISQLPPSVFMQLPQLNRLTLFGNSLKELSPGIFGPMPNLRELWLY 301
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
N + LPD++FS LR L + L N+IS IS F G T +R L L N L +++
Sbjct: 302 DNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNALQDLDGNVF 361
Query: 53 SPLNQLHKL 27
L L +
Sbjct: 362 RMLANLQNI 370
Score = 88.2 bits (209), Expect = 2e-17
Identities = 55/169 (32%), Positives = 87/169 (51%), Gaps = 1/169 (0%)
Frame = -3
Query: 530 IKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRALP 354
++I N L E+ F N+ AL L+++ + + + P F + LR LSLA N+L+ LP
Sbjct: 58 LQILNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLP 117
Query: 353 RSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTT 174
+ +G L SL LS N + ++ P F+ L+ + GN L+ +PD F L LT
Sbjct: 118 IGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTK 177
Query: 173 VSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
++L N ++ IS FQ +++ L L NRL P + L L +L
Sbjct: 178 LNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQEL 226
Score = 81.8 bits (193), Expect = 2e-15
Identities = 49/179 (27%), Positives = 86/179 (48%), Gaps = 1/179 (0%)
Frame = -3
Query: 557 FRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSL 381
F GL ++QE+ + N L +F N L+ L L + I +LP P L L+L
Sbjct: 217 FDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSVFMQLPQLNRLTL 276
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSL 201
N L+ L + L L L N ++ L +F++LR L+ ++ N++ +
Sbjct: 277 FGNSLKELSPGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGA 336
Query: 200 FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
F+GL L +SL N + + N F+ +++ + L NRL P ++++ +N L +Q
Sbjct: 337 FNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQ 395
Score = 77.4 bits (182), Expect = 4e-14
Identities = 52/194 (26%), Positives = 90/194 (46%), Gaps = 1/194 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFI 411
N Y+ F L + ++ + N + VF +L L+ L+L + + ++P F
Sbjct: 159 NHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFD 218
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L+ L+L +NQ+ L + L L LS N +++L P +F L L + G
Sbjct: 219 GLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSVFMQLPQLNRLTLFG 278
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N L+ L +F + NL + L +N IS + N F ++ L LS N+++F ++
Sbjct: 279 NSLKELSPGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFN 338
Query: 50 PLNQLHKLQTLTLA 9
L +L +L T A
Sbjct: 339 GLTELRELSLHTNA 352
Score = 72.5 bits (170), Expect = 1e-12
Identities = 57/216 (26%), Positives = 96/216 (44%), Gaps = 25/216 (11%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE 420
++ N + L +F+GLD ++ + +S+N L ++ A FS L+ LQL + + +P+
Sbjct: 107 SLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPD 166
Query: 419 EFISN-----------------SP--------LRTLSLARNQLRALPRSVLRGQTQLTSL 315
+ SP L+ L L N+L +P G L L
Sbjct: 167 GAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQEL 226
Query: 314 TLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISM 135
L N + L+P LF + L+ + N + LP S+F L L ++L N + +S
Sbjct: 227 ALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSVFMQLPQLNRLTLFGNSLKELSP 286
Query: 134 NTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
F ++R L L N ++ PD+++S L QL L
Sbjct: 287 GIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVL 322
Score = 68.5 bits (160), Expect = 2e-11
Identities = 46/149 (30%), Positives = 77/149 (51%), Gaps = 1/149 (0%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-P 423
T+ NS + L IF + +++E+ + +N +L + VFSNL L+ L L + I + P
Sbjct: 275 TLFGNSLKELSPGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISP 334
Query: 422 EEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETF 243
F + LR LSL N L+ L +V R L +++L N + +L +FA++ L
Sbjct: 335 GAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAI 394
Query: 242 VMDGNELQVLPDSLFSGLRNLTTVSLRNN 156
+ N+L+ LP +F L L + L +N
Sbjct: 395 QLQNNQLENLPLGIFDHLGKLCELRLYDN 423
Score = 59.7 bits (138), Expect = 8e-09
Identities = 35/122 (28%), Positives = 60/122 (49%)
Frame = -3
Query: 392 TLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVL 213
+L + + L S + L +L + N ++ + P F +L +L + N+LQVL
Sbjct: 57 SLQILNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVL 116
Query: 212 PDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLH 33
P LF GL +L ++ L +N++ I F ++++ L L N L + PD + L L
Sbjct: 117 PIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLT 176
Query: 32 KL 27
KL
Sbjct: 177 KL 178
Score = 52.4 bits (120), Expect = 1e-06
Identities = 32/99 (32%), Positives = 51/99 (51%)
Frame = -3
Query: 320 SLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVI 141
SL + + EL F ++ AL ++ NEL + F L +L +SL NNK+ V+
Sbjct: 57 SLQILNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVL 116
Query: 140 SMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
+ FQG S+ +L LS N+L + +S + L +LQ
Sbjct: 117 PIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQ 155
>BC101064-1|AAI01065.1| 581|Homo sapiens leucine rich repeat
containing 15 protein.
Length = 581
Score = 95.1 bits (226), Expect = 2e-19
Identities = 60/189 (31%), Positives = 93/189 (49%), Gaps = 1/189 (0%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEF 414
+NS ++ +F+ L ++Q +++ N + F L L+ L L + I L P F
Sbjct: 182 KNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLF 241
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
+N L+ L L+ N + LP SV QL LTL N++ EL+P +F + L +
Sbjct: 242 HNNHNLQRLYLSNNHISQLPPSVFMQLPQLNRLTLFGNSLKELSPGIFGPMPNLRELWLY 301
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
N + LPD++FS LR L + L N+IS IS F G T +R L L N L +++
Sbjct: 302 DNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNALQDLDGNVF 361
Query: 53 SPLNQLHKL 27
L L +
Sbjct: 362 RMLANLQNI 370
Score = 88.2 bits (209), Expect = 2e-17
Identities = 55/169 (32%), Positives = 87/169 (51%), Gaps = 1/169 (0%)
Frame = -3
Query: 530 IKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRALP 354
++I N L E+ F N+ AL L+++ + + + P F + LR LSLA N+L+ LP
Sbjct: 58 LQILNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLP 117
Query: 353 RSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTT 174
+ +G L SL LS N + ++ P F+ L+ + GN L+ +PD F L LT
Sbjct: 118 IGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTK 177
Query: 173 VSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
++L N ++ IS FQ +++ L L NRL P + L L +L
Sbjct: 178 LNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQEL 226
Score = 81.8 bits (193), Expect = 2e-15
Identities = 49/179 (27%), Positives = 86/179 (48%), Gaps = 1/179 (0%)
Frame = -3
Query: 557 FRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSL 381
F GL ++QE+ + N L +F N L+ L L + I +LP P L L+L
Sbjct: 217 FDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSVFMQLPQLNRLTL 276
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSL 201
N L+ L + L L L N ++ L +F++LR L+ ++ N++ +
Sbjct: 277 FGNSLKELSPGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGA 336
Query: 200 FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
F+GL L +SL N + + N F+ +++ + L NRL P ++++ +N L +Q
Sbjct: 337 FNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQ 395
Score = 77.4 bits (182), Expect = 4e-14
Identities = 52/194 (26%), Positives = 90/194 (46%), Gaps = 1/194 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFI 411
N Y+ F L + ++ + N + VF +L L+ L+L + + ++P F
Sbjct: 159 NHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFD 218
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L+ L+L +NQ+ L + L L LS N +++L P +F L L + G
Sbjct: 219 GLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSVFMQLPQLNRLTLFG 278
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N L+ L +F + NL + L +N IS + N F ++ L LS N+++F ++
Sbjct: 279 NSLKELSPGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFN 338
Query: 50 PLNQLHKLQTLTLA 9
L +L +L T A
Sbjct: 339 GLTELRELSLHTNA 352
Score = 72.5 bits (170), Expect = 1e-12
Identities = 57/216 (26%), Positives = 96/216 (44%), Gaps = 25/216 (11%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE 420
++ N + L +F+GLD ++ + +S+N L ++ A FS L+ LQL + + +P+
Sbjct: 107 SLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPD 166
Query: 419 EFISN-----------------SP--------LRTLSLARNQLRALPRSVLRGQTQLTSL 315
+ SP L+ L L N+L +P G L L
Sbjct: 167 GAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQEL 226
Query: 314 TLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISM 135
L N + L+P LF + L+ + N + LP S+F L L ++L N + +S
Sbjct: 227 ALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSVFMQLPQLNRLTLFGNSLKELSP 286
Query: 134 NTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
F ++R L L N ++ PD+++S L QL L
Sbjct: 287 GIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVL 322
Score = 68.5 bits (160), Expect = 2e-11
Identities = 46/149 (30%), Positives = 77/149 (51%), Gaps = 1/149 (0%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-P 423
T+ NS + L IF + +++E+ + +N +L + VFSNL L+ L L + I + P
Sbjct: 275 TLFGNSLKELSPGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISP 334
Query: 422 EEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETF 243
F + LR LSL N L+ L +V R L +++L N + +L +FA++ L
Sbjct: 335 GAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAI 394
Query: 242 VMDGNELQVLPDSLFSGLRNLTTVSLRNN 156
+ N+L+ LP +F L L + L +N
Sbjct: 395 QLQNNQLENLPLGIFDHLGKLCELRLYDN 423
Score = 59.7 bits (138), Expect = 8e-09
Identities = 35/122 (28%), Positives = 60/122 (49%)
Frame = -3
Query: 392 TLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVL 213
+L + + L S + L +L + N ++ + P F +L +L + N+LQVL
Sbjct: 57 SLQILNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVL 116
Query: 212 PDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLH 33
P LF GL +L ++ L +N++ I F ++++ L L N L + PD + L L
Sbjct: 117 PIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLT 176
Query: 32 KL 27
KL
Sbjct: 177 KL 178
Score = 52.4 bits (120), Expect = 1e-06
Identities = 32/99 (32%), Positives = 51/99 (51%)
Frame = -3
Query: 320 SLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVI 141
SL + + EL F ++ AL ++ NEL + F L +L +SL NNK+ V+
Sbjct: 57 SLQILNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVL 116
Query: 140 SMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
+ FQG S+ +L LS N+L + +S + L +LQ
Sbjct: 117 PIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQ 155
>BC096326-1|AAH96326.1| 883|Homo sapiens LGR5 protein protein.
Length = 883
Score = 93.9 bits (223), Expect = 4e-19
Identities = 54/175 (30%), Positives = 90/175 (51%), Gaps = 3/175 (1%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARN 372
L ++E++++ N + + F+ L +L+ L L + +R +P E + N L++L L N
Sbjct: 89 LRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDAN 148
Query: 371 QLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSG 192
+ +P S G L L L NA+ E+ + F L AL+ + N++ +PD F
Sbjct: 149 HISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGN 208
Query: 191 LRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL--YSPLNQLH 33
L +L + L NN+I + F G S+ TLDL+YN L P ++ S L +LH
Sbjct: 209 LSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELH 263
Score = 73.3 bits (172), Expect = 6e-13
Identities = 58/185 (31%), Positives = 92/185 (49%), Gaps = 1/185 (0%)
Frame = -3
Query: 554 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLD-LSSIRELPEEFISNSPLRTLSLA 378
R L +++E+ +N + + F +LP LRTL L+ S I E P+ + L +L+L
Sbjct: 254 RTLSNLKELHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPD-LTGTANLESLTLT 312
Query: 377 RNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLF 198
Q+ +LP++V L L LSYN + +L F+ + L+ + NE+ + F
Sbjct: 313 GAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS--FSVCQKLQKIDLRHNEIYEIKVDTF 370
Query: 197 SGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTL 18
L +L +++L NKI++I N F S+ LDLS N L+ P+ LH L L
Sbjct: 371 QQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLS------SFPITGLHGLTHL 424
Query: 17 TLAWN 3
L N
Sbjct: 425 KLTGN 429
Score = 72.1 bits (169), Expect = 1e-12
Identities = 44/151 (29%), Positives = 77/151 (50%), Gaps = 2/151 (1%)
Frame = -3
Query: 482 SNLPALRT-LQLDLSSIREL-PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTL 309
SNL + L L +++I +L P S L L LA N L +P+ G L L L
Sbjct: 62 SNLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLML 121
Query: 308 SYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNT 129
N + + E +LR+L++ +D N + +P S FSGL +L + L +N ++ I +
Sbjct: 122 QNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQA 181
Query: 128 FQGATSIRTLDLSYNRLAFAPDSLYSPLNQL 36
F+ ++++ + L+ N++ PD + L+ L
Sbjct: 182 FRSLSALQAMTLALNKIHHIPDYAFGNLSSL 212
Score = 66.9 bits (156), Expect = 5e-11
Identities = 53/173 (30%), Positives = 80/173 (46%), Gaps = 1/173 (0%)
Frame = -3
Query: 518 NNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRALPRSVL 342
NN+ L + S L L L+L +++ +P+ F L+ L L NQLR +P L
Sbjct: 76 NNISQLLPNPLPS-LRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEAL 134
Query: 341 RGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLR 162
+ L SL L N ++ + P F+ L +L +D N L +P F L L ++L
Sbjct: 135 QNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLA 194
Query: 161 NNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
NKI I F +S+ L L NR+ + + LH L+TL L +N
Sbjct: 195 LNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCF---DGLHSLETLDLNYN 244
Score = 65.7 bits (153), Expect = 1e-10
Identities = 63/216 (29%), Positives = 103/216 (47%), Gaps = 25/216 (11%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLD--------- 447
T+ N ++ F L + + + NN +L + F L +L TL L+
Sbjct: 192 TLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPT 251
Query: 446 ----LSSIREL-----PEEFISNSP------LRTLSL-ARNQLRALPRSVLRGQTQLTSL 315
LS+++EL P +F+ S LRTL+L +Q+ P L G L SL
Sbjct: 252 AIRTLSNLKELHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPD--LTGTANLESL 309
Query: 314 TLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISM 135
TL+ ++ L + L L+ + N L+ LP FS + L + LR+N+I I +
Sbjct: 310 TLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS--FSVCQKLQKIDLRHNEIYEIKV 367
Query: 134 NTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+TFQ S+R+L+L++N++A + +S L L KL
Sbjct: 368 DTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKL 403
Score = 63.3 bits (147), Expect = 6e-10
Identities = 32/97 (32%), Positives = 52/97 (53%)
Frame = -3
Query: 317 LTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVIS 138
L LS N +++L P LR LE + GN L +P F+GL +L + L+NN++ +
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 137 MNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
Q S+++L L N +++ P S +S L+ L L
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHL 167
Score = 54.4 bits (125), Expect = 3e-07
Identities = 39/129 (30%), Positives = 60/129 (46%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
L L+ N + L + L L L L+ NA+ + F L +L+ ++ N+L+ +P
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHK 30
LR+L ++ L N IS + + F G S+R L L N L P + L
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAF---RSLSA 187
Query: 29 LQTLTLAWN 3
LQ +TLA N
Sbjct: 188 LQAMTLALN 196
>BC096325-1|AAH96325.1| 883|Homo sapiens LGR5 protein protein.
Length = 883
Score = 93.9 bits (223), Expect = 4e-19
Identities = 54/175 (30%), Positives = 90/175 (51%), Gaps = 3/175 (1%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARN 372
L ++E++++ N + + F+ L +L+ L L + +R +P E + N L++L L N
Sbjct: 89 LRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDAN 148
Query: 371 QLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSG 192
+ +P S G L L L NA+ E+ + F L AL+ + N++ +PD F
Sbjct: 149 HISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGN 208
Query: 191 LRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL--YSPLNQLH 33
L +L + L NN+I + F G S+ TLDL+YN L P ++ S L +LH
Sbjct: 209 LSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELH 263
Score = 73.3 bits (172), Expect = 6e-13
Identities = 58/185 (31%), Positives = 92/185 (49%), Gaps = 1/185 (0%)
Frame = -3
Query: 554 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLD-LSSIRELPEEFISNSPLRTLSLA 378
R L +++E+ +N + + F +LP LRTL L+ S I E P+ + L +L+L
Sbjct: 254 RTLSNLKELHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPD-LTGTANLESLTLT 312
Query: 377 RNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLF 198
Q+ +LP++V L L LSYN + +L F+ + L+ + NE+ + F
Sbjct: 313 GAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS--FSVCQKLQKIDLRHNEIYEIKVDTF 370
Query: 197 SGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTL 18
L +L +++L NKI++I N F S+ LDLS N L+ P+ LH L L
Sbjct: 371 QQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLS------SFPITGLHGLTHL 424
Query: 17 TLAWN 3
L N
Sbjct: 425 KLTGN 429
Score = 72.1 bits (169), Expect = 1e-12
Identities = 44/151 (29%), Positives = 77/151 (50%), Gaps = 2/151 (1%)
Frame = -3
Query: 482 SNLPALRT-LQLDLSSIREL-PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTL 309
SNL + L L +++I +L P S L L LA N L +P+ G L L L
Sbjct: 62 SNLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLML 121
Query: 308 SYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNT 129
N + + E +LR+L++ +D N + +P S FSGL +L + L +N ++ I +
Sbjct: 122 QNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQA 181
Query: 128 FQGATSIRTLDLSYNRLAFAPDSLYSPLNQL 36
F+ ++++ + L+ N++ PD + L+ L
Sbjct: 182 FRSLSALQAMTLALNKIHHIPDYAFGNLSSL 212
Score = 66.9 bits (156), Expect = 5e-11
Identities = 53/173 (30%), Positives = 80/173 (46%), Gaps = 1/173 (0%)
Frame = -3
Query: 518 NNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRALPRSVL 342
NN+ L + S L L L+L +++ +P+ F L+ L L NQLR +P L
Sbjct: 76 NNISQLLPNPLPS-LRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEAL 134
Query: 341 RGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLR 162
+ L SL L N ++ + P F+ L +L +D N L +P F L L ++L
Sbjct: 135 QNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLA 194
Query: 161 NNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
NKI I F +S+ L L NR+ + + LH L+TL L +N
Sbjct: 195 LNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCF---DGLHSLETLDLNYN 244
Score = 65.7 bits (153), Expect = 1e-10
Identities = 63/216 (29%), Positives = 103/216 (47%), Gaps = 25/216 (11%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLD--------- 447
T+ N ++ F L + + + NN +L + F L +L TL L+
Sbjct: 192 TLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPT 251
Query: 446 ----LSSIREL-----PEEFISNSP------LRTLSL-ARNQLRALPRSVLRGQTQLTSL 315
LS+++EL P +F+ S LRTL+L +Q+ P L G L SL
Sbjct: 252 AIRTLSNLKELHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPD--LTGTANLESL 309
Query: 314 TLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISM 135
TL+ ++ L + L L+ + N L+ LP FS + L + LR+N+I I +
Sbjct: 310 TLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS--FSVCQKLQKIDLRHNEIYEIKV 367
Query: 134 NTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+TFQ S+R+L+L++N++A + +S L L KL
Sbjct: 368 DTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKL 403
Score = 63.3 bits (147), Expect = 6e-10
Identities = 32/97 (32%), Positives = 52/97 (53%)
Frame = -3
Query: 317 LTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVIS 138
L LS N +++L P LR LE + GN L +P F+GL +L + L+NN++ +
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 137 MNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
Q S+++L L N +++ P S +S L+ L L
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHL 167
Score = 54.4 bits (125), Expect = 3e-07
Identities = 39/129 (30%), Positives = 60/129 (46%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
L L+ N + L + L L L L+ NA+ + F L +L+ ++ N+L+ +P
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHK 30
LR+L ++ L N IS + + F G S+R L L N L P + L
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAF---RSLSA 187
Query: 29 LQTLTLAWN 3
LQ +TLA N
Sbjct: 188 LQAMTLALN 196
>AF346711-1|AAK31153.1| 951|Homo sapiens G-protein couple receptor
protein.
Length = 951
Score = 93.5 bits (222), Expect = 5e-19
Identities = 51/178 (28%), Positives = 90/178 (50%), Gaps = 1/178 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N+ L + F+ ++E++++ N + S L L+ L L + ++ +P E I
Sbjct: 67 NNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIR 126
Query: 407 N-SPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
S L++L L N + ++P G QL L L N++ E+ ++L L+ +
Sbjct: 127 GLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLAL 186
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
N++ +PD F+ L +L + L NNKI +S + F G ++ TLDLSYN L P ++
Sbjct: 187 NKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGEFPQAI 244
Score = 93.5 bits (222), Expect = 5e-19
Identities = 61/192 (31%), Positives = 95/192 (49%), Gaps = 1/192 (0%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE 420
T+ N + + SE RGL +Q +++ N ++ E F L LR L LD +S+ E+P
Sbjct: 111 TLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPV 170
Query: 419 EFISNSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETF 243
+SN P L+ L+LA N++ ++P + L L L N + L+ F L LET
Sbjct: 171 HPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETL 230
Query: 242 VMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPD 63
+ N L P ++ +L + +N ISVI F G +RT+ L N L+F +
Sbjct: 231 DLSYNNLGEFPQAI-KARPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGN 289
Query: 62 SLYSPLNQLHKL 27
S + L+ LH L
Sbjct: 290 SAFHNLSDLHSL 301
Score = 76.2 bits (179), Expect = 8e-14
Identities = 59/181 (32%), Positives = 83/181 (45%), Gaps = 3/181 (1%)
Frame = -3
Query: 536 QEIKISNNVPLTLKEAVFSNLPALRTLQL---DLSSIRELPEEFISNSPLRTLSLARNQL 366
Q + IS N L E F N P L LQL DLS I P+ L+ L+L NQL
Sbjct: 60 QALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIH--PKALSGLKELKVLTLQNNQL 117
Query: 365 RALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLR 186
+ +P +RG + L SL L N + + + F L L +D N L +P S L
Sbjct: 118 KTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLP 177
Query: 185 NLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAW 6
L ++L NKIS I F +S+ L L N++ + L+ L+TL L++
Sbjct: 178 TLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLD---NLETLDLSY 234
Query: 5 N 3
N
Sbjct: 235 N 235
Score = 68.5 bits (160), Expect = 2e-11
Identities = 49/184 (26%), Positives = 83/184 (45%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
NS + F G ++ I + +N + + F NL L +L + +S+ +
Sbjct: 258 NSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFPNLTG 317
Query: 407 NSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 228
L +L+L ++ ++P ++ + Q L +L LSYN + +L F ALE + N
Sbjct: 318 TVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLPS--FNGCHALEEISLQRN 375
Query: 227 ELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSP 48
++ + + F GL +L + L N I I F I LD+S+N L P +
Sbjct: 376 QIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFPTEGLNG 435
Query: 47 LNQL 36
LNQL
Sbjct: 436 LNQL 439
>AF257182-1|AAF68989.1| 951|Homo sapiens G-protein-coupled receptor
48 protein.
Length = 951
Score = 93.5 bits (222), Expect = 5e-19
Identities = 51/178 (28%), Positives = 90/178 (50%), Gaps = 1/178 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N+ L + F+ ++E++++ N + S L L+ L L + ++ +P E I
Sbjct: 67 NNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIR 126
Query: 407 N-SPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
S L++L L N + ++P G QL L L N++ E+ ++L L+ +
Sbjct: 127 GLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLAL 186
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
N++ +PD F+ L +L + L NNKI +S + F G ++ TLDLSYN L P ++
Sbjct: 187 NKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGEFPQAI 244
Score = 91.5 bits (217), Expect = 2e-18
Identities = 61/192 (31%), Positives = 94/192 (48%), Gaps = 1/192 (0%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE 420
T+ N + + SE RGL +Q +++ N ++ E F L LR L LD +S+ E+P
Sbjct: 111 TLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPV 170
Query: 419 EFISNSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETF 243
+SN P L+ L+LA N++ ++P + L L L N + L+ F L LET
Sbjct: 171 HPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETL 230
Query: 242 VMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPD 63
+ N L P ++ +L + +N ISVI F G +RT+ L N L+F +
Sbjct: 231 DLSYNNLGEFPQAI-KARPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGN 289
Query: 62 SLYSPLNQLHKL 27
S L+ LH L
Sbjct: 290 SASHNLSDLHSL 301
Score = 76.2 bits (179), Expect = 8e-14
Identities = 59/181 (32%), Positives = 83/181 (45%), Gaps = 3/181 (1%)
Frame = -3
Query: 536 QEIKISNNVPLTLKEAVFSNLPALRTLQL---DLSSIRELPEEFISNSPLRTLSLARNQL 366
Q + IS N L E F N P L LQL DLS I P+ L+ L+L NQL
Sbjct: 60 QALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIH--PKALSGLKELKVLTLQNNQL 117
Query: 365 RALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLR 186
+ +P +RG + L SL L N + + + F L L +D N L +P S L
Sbjct: 118 KTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLP 177
Query: 185 NLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAW 6
L ++L NKIS I F +S+ L L N++ + L+ L+TL L++
Sbjct: 178 TLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLD---NLETLDLSY 234
Query: 5 N 3
N
Sbjct: 235 N 235
Score = 64.5 bits (150), Expect = 3e-10
Identities = 48/184 (26%), Positives = 82/184 (44%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
NS + F G ++ I + +N + + NL L +L + +S+ +
Sbjct: 258 NSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSASHNLSDLHSLVIRGASMVQQFPNLTG 317
Query: 407 NSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 228
L +L+L ++ ++P ++ + Q L +L LSYN + +L F ALE + N
Sbjct: 318 TVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLPS--FNGCHALEEISLQRN 375
Query: 227 ELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSP 48
++ + + F GL +L + L N I I F I LD+S+N L P +
Sbjct: 376 QIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFPTEGPNG 435
Query: 47 LNQL 36
LNQL
Sbjct: 436 LNQL 439
>BC099650-1|AAH99650.1| 907|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 5 protein.
Length = 907
Score = 91.9 bits (218), Expect = 2e-18
Identities = 53/175 (30%), Positives = 91/175 (52%), Gaps = 1/175 (0%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARN 372
L ++E++++ N + + F+ L +L+ L L + +R +P E + N L++L L N
Sbjct: 89 LRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDAN 148
Query: 371 QLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSG 192
+ +P S G L L L NA+ E+ + F L AL+ + N++ +PD F
Sbjct: 149 HISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGN 208
Query: 191 LRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
L +L + L NN+I + F G S+ TLDL+YN L P ++ + L+ L +L
Sbjct: 209 LSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRT-LSNLKEL 262
Score = 72.9 bits (171), Expect = 8e-13
Identities = 60/196 (30%), Positives = 94/196 (47%), Gaps = 1/196 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLD-LSSIRELPEEFI 411
N+ R + + F G + I +N + + F +LP LRTL L+ S I E P +
Sbjct: 267 NNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFP-DLT 325
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
+ L +L+L Q+ +LP++V L L LSYN + +L F+ + L+ +
Sbjct: 326 GTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS--FSVCQKLQKIDLRH 383
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
NE+ + F L +L +++L NKI++I N F S+ LDLS N L+
Sbjct: 384 NEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLS------SF 437
Query: 50 PLNQLHKLQTLTLAWN 3
P+ LH L L L N
Sbjct: 438 PITGLHGLTHLKLTGN 453
Score = 72.1 bits (169), Expect = 1e-12
Identities = 44/151 (29%), Positives = 77/151 (50%), Gaps = 2/151 (1%)
Frame = -3
Query: 482 SNLPALRT-LQLDLSSIREL-PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTL 309
SNL + L L +++I +L P S L L LA N L +P+ G L L L
Sbjct: 62 SNLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLML 121
Query: 308 SYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNT 129
N + + E +LR+L++ +D N + +P S FSGL +L + L +N ++ I +
Sbjct: 122 QNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQA 181
Query: 128 FQGATSIRTLDLSYNRLAFAPDSLYSPLNQL 36
F+ ++++ + L+ N++ PD + L+ L
Sbjct: 182 FRSLSALQAMTLALNKIHHIPDYAFGNLSSL 212
Score = 69.7 bits (163), Expect = 7e-12
Identities = 54/178 (30%), Positives = 92/178 (51%), Gaps = 2/178 (1%)
Frame = -3
Query: 554 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSL- 381
R L +++E+ +N ++ E F P+L T+ + I+ + + P LRTL+L
Sbjct: 254 RTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLN 313
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSL 201
+Q+ P L G L SLTL+ ++ L + L L+ + N L+ LP
Sbjct: 314 GASQITEFPD--LTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS-- 369
Query: 200 FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
FS + L + LR+N+I I ++TFQ S+R+L+L++N++A + +S L L KL
Sbjct: 370 FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKL 427
Score = 63.3 bits (147), Expect = 6e-10
Identities = 32/97 (32%), Positives = 52/97 (53%)
Frame = -3
Query: 317 LTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVIS 138
L LS N +++L P LR LE + GN L +P F+GL +L + L+NN++ +
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 137 MNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
Q S+++L L N +++ P S +S L+ L L
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHL 167
Score = 54.4 bits (125), Expect = 3e-07
Identities = 39/129 (30%), Positives = 60/129 (46%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
L L+ N + L + L L L L+ NA+ + F L +L+ ++ N+L+ +P
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHK 30
LR+L ++ L N IS + + F G S+R L L N L P + L
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAF---RSLSA 187
Query: 29 LQTLTLAWN 3
LQ +TLA N
Sbjct: 188 LQAMTLALN 196
>BC096324-1|AAH96324.1| 907|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 5 protein.
Length = 907
Score = 91.9 bits (218), Expect = 2e-18
Identities = 53/175 (30%), Positives = 91/175 (52%), Gaps = 1/175 (0%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARN 372
L ++E++++ N + + F+ L +L+ L L + +R +P E + N L++L L N
Sbjct: 89 LRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDAN 148
Query: 371 QLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSG 192
+ +P S G L L L NA+ E+ + F L AL+ + N++ +PD F
Sbjct: 149 HISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGN 208
Query: 191 LRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
L +L + L NN+I + F G S+ TLDL+YN L P ++ + L+ L +L
Sbjct: 209 LSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRT-LSNLKEL 262
Score = 72.9 bits (171), Expect = 8e-13
Identities = 60/196 (30%), Positives = 94/196 (47%), Gaps = 1/196 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLD-LSSIRELPEEFI 411
N+ R + + F G + I +N + + F +LP LRTL L+ S I E P +
Sbjct: 267 NNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFP-DLT 325
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
+ L +L+L Q+ +LP++V L L LSYN + +L F+ + L+ +
Sbjct: 326 GTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS--FSVCQKLQKIDLRH 383
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
NE+ + F L +L +++L NKI++I N F S+ LDLS N L+
Sbjct: 384 NEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLS------SF 437
Query: 50 PLNQLHKLQTLTLAWN 3
P+ LH L L L N
Sbjct: 438 PITGLHGLTHLKLTGN 453
Score = 72.1 bits (169), Expect = 1e-12
Identities = 44/151 (29%), Positives = 77/151 (50%), Gaps = 2/151 (1%)
Frame = -3
Query: 482 SNLPALRT-LQLDLSSIREL-PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTL 309
SNL + L L +++I +L P S L L LA N L +P+ G L L L
Sbjct: 62 SNLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLML 121
Query: 308 SYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNT 129
N + + E +LR+L++ +D N + +P S FSGL +L + L +N ++ I +
Sbjct: 122 QNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQA 181
Query: 128 FQGATSIRTLDLSYNRLAFAPDSLYSPLNQL 36
F+ ++++ + L+ N++ PD + L+ L
Sbjct: 182 FRSLSALQAMTLALNKIHHIPDYAFGNLSSL 212
Score = 69.7 bits (163), Expect = 7e-12
Identities = 54/178 (30%), Positives = 92/178 (51%), Gaps = 2/178 (1%)
Frame = -3
Query: 554 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSL- 381
R L +++E+ +N ++ E F P+L T+ + I+ + + P LRTL+L
Sbjct: 254 RTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLN 313
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSL 201
+Q+ P L G L SLTL+ ++ L + L L+ + N L+ LP
Sbjct: 314 GASQITEFPD--LTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS-- 369
Query: 200 FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
FS + L + LR+N+I I ++TFQ S+R+L+L++N++A + +S L L KL
Sbjct: 370 FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKL 427
Score = 63.3 bits (147), Expect = 6e-10
Identities = 32/97 (32%), Positives = 52/97 (53%)
Frame = -3
Query: 317 LTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVIS 138
L LS N +++L P LR LE + GN L +P F+GL +L + L+NN++ +
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 137 MNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
Q S+++L L N +++ P S +S L+ L L
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHL 167
Score = 54.4 bits (125), Expect = 3e-07
Identities = 39/129 (30%), Positives = 60/129 (46%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
L L+ N + L + L L L L+ NA+ + F L +L+ ++ N+L+ +P
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHK 30
LR+L ++ L N IS + + F G S+R L L N L P + L
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAF---RSLSA 187
Query: 29 LQTLTLAWN 3
LQ +TLA N
Sbjct: 188 LQAMTLALN 196
>AF062006-1|AAC28019.1| 907|Homo sapiens orphan G protein-coupled
receptor HG38 protein.
Length = 907
Score = 91.9 bits (218), Expect = 2e-18
Identities = 53/175 (30%), Positives = 91/175 (52%), Gaps = 1/175 (0%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARN 372
L ++E++++ N + + F+ L +L+ L L + +R +P E + N L++L L N
Sbjct: 89 LRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDAN 148
Query: 371 QLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSG 192
+ +P S G L L L NA+ E+ + F L AL+ + N++ +PD F
Sbjct: 149 HISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGN 208
Query: 191 LRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
L +L + L NN+I + F G S+ TLDL+YN L P ++ + L+ L +L
Sbjct: 209 LSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRT-LSNLKEL 262
Score = 72.9 bits (171), Expect = 8e-13
Identities = 60/196 (30%), Positives = 94/196 (47%), Gaps = 1/196 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLD-LSSIRELPEEFI 411
N+ R + + F G + I +N + + F +LP LRTL L+ S I E P +
Sbjct: 267 NNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFP-DLT 325
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
+ L +L+L Q+ +LP++V L L LSYN + +L F+ + L+ +
Sbjct: 326 GTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS--FSVCQKLQKIDLRH 383
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
NE+ + F L +L +++L NKI++I N F S+ LDLS N L+
Sbjct: 384 NEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLS------SF 437
Query: 50 PLNQLHKLQTLTLAWN 3
P+ LH L L L N
Sbjct: 438 PITGLHGLTHLKLTGN 453
Score = 72.1 bits (169), Expect = 1e-12
Identities = 44/151 (29%), Positives = 77/151 (50%), Gaps = 2/151 (1%)
Frame = -3
Query: 482 SNLPALRT-LQLDLSSIREL-PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTL 309
SNL + L L +++I +L P S L L LA N L +P+ G L L L
Sbjct: 62 SNLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLML 121
Query: 308 SYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNT 129
N + + E +LR+L++ +D N + +P S FSGL +L + L +N ++ I +
Sbjct: 122 QNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQA 181
Query: 128 FQGATSIRTLDLSYNRLAFAPDSLYSPLNQL 36
F+ ++++ + L+ N++ PD + L+ L
Sbjct: 182 FRSLSALQAMTLALNKIHHIPDYAFGNLSSL 212
Score = 69.7 bits (163), Expect = 7e-12
Identities = 54/178 (30%), Positives = 92/178 (51%), Gaps = 2/178 (1%)
Frame = -3
Query: 554 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSL- 381
R L +++E+ +N ++ E F P+L T+ + I+ + + P LRTL+L
Sbjct: 254 RTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLN 313
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSL 201
+Q+ P L G L SLTL+ ++ L + L L+ + N L+ LP
Sbjct: 314 GASQITEFPD--LTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS-- 369
Query: 200 FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
FS + L + LR+N+I I ++TFQ S+R+L+L++N++A + +S L L KL
Sbjct: 370 FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKL 427
Score = 63.3 bits (147), Expect = 6e-10
Identities = 32/97 (32%), Positives = 52/97 (53%)
Frame = -3
Query: 317 LTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVIS 138
L LS N +++L P LR LE + GN L +P F+GL +L + L+NN++ +
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 137 MNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
Q S+++L L N +++ P S +S L+ L L
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHL 167
Score = 54.4 bits (125), Expect = 3e-07
Identities = 39/129 (30%), Positives = 60/129 (46%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
L L+ N + L + L L L L+ NA+ + F L +L+ ++ N+L+ +P
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHK 30
LR+L ++ L N IS + + F G S+R L L N L P + L
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAF---RSLSA 187
Query: 29 LQTLTLAWN 3
LQ +TLA N
Sbjct: 188 LQAMTLALN 196
>AB071037-1|BAB84587.1| 581|Homo sapiens Lib protein.
Length = 581
Score = 90.6 bits (215), Expect = 4e-18
Identities = 58/189 (30%), Positives = 92/189 (48%), Gaps = 1/189 (0%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEF 414
+NS ++ +F+ L ++Q +++ N + F L L+ L L + I L P F
Sbjct: 182 KNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLF 241
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
+N L+ L L+ N + LP S+ QL LTL N++ EL+ +F + L +
Sbjct: 242 HNNHNLQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPMPNLRELWLY 301
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
N + LPD++FS LR L + L N+IS IS F G T +R L L N L +++
Sbjct: 302 DNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNALQDLDGNVF 361
Query: 53 SPLNQLHKL 27
L L +
Sbjct: 362 RMLANLQNI 370
Score = 88.2 bits (209), Expect = 2e-17
Identities = 55/169 (32%), Positives = 87/169 (51%), Gaps = 1/169 (0%)
Frame = -3
Query: 530 IKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRALP 354
++I N L E+ F N+ AL L+++ + + + P F + LR LSLA N+L+ LP
Sbjct: 58 LQILNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLP 117
Query: 353 RSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTT 174
+ +G L SL LS N + ++ P F+ L+ + GN L+ +PD F L LT
Sbjct: 118 IGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTK 177
Query: 173 VSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
++L N ++ IS FQ +++ L L NRL P + L L +L
Sbjct: 178 LNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQEL 226
Score = 82.2 bits (194), Expect = 1e-15
Identities = 49/179 (27%), Positives = 86/179 (48%), Gaps = 1/179 (0%)
Frame = -3
Query: 557 FRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSL 381
F GL ++QE+ + N L +F N L+ L L + I +LP P L L+L
Sbjct: 217 FDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSIFMQLPQLNRLTL 276
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSL 201
N L+ L + L L L N ++ L +F++LR L+ ++ N++ +
Sbjct: 277 FGNSLKELSLGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGA 336
Query: 200 FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
F+GL L +SL N + + N F+ +++ + L NRL P ++++ +N L +Q
Sbjct: 337 FNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQ 395
Score = 76.6 bits (180), Expect = 6e-14
Identities = 52/194 (26%), Positives = 90/194 (46%), Gaps = 1/194 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFI 411
N Y+ F L + ++ + N + VF +L L+ L+L + + ++P F
Sbjct: 159 NHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFD 218
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L+ L+L +NQ+ L + L L LS N +++L P +F L L + G
Sbjct: 219 GLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSIFMQLPQLNRLTLFG 278
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N L+ L +F + NL + L +N IS + N F ++ L LS N+++F ++
Sbjct: 279 NSLKELSLGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFN 338
Query: 50 PLNQLHKLQTLTLA 9
L +L +L T A
Sbjct: 339 GLTELRELSLHTNA 352
Score = 74.5 bits (175), Expect = 3e-13
Identities = 57/216 (26%), Positives = 97/216 (44%), Gaps = 25/216 (11%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE 420
++ N + L +F+GLD ++ + +S+N L ++ A FS L+ LQL + + +P+
Sbjct: 107 SLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPD 166
Query: 419 EFISN-----------------SP--------LRTLSLARNQLRALPRSVLRGQTQLTSL 315
+ SP L+ L L N+L +P G L L
Sbjct: 167 GAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQEL 226
Query: 314 TLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISM 135
L N + L+P LF + L+ + N + LP S+F L L ++L N + +S+
Sbjct: 227 ALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKELSL 286
Query: 134 NTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
F ++R L L N ++ PD+++S L QL L
Sbjct: 287 GIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVL 322
Score = 68.1 bits (159), Expect = 2e-11
Identities = 46/149 (30%), Positives = 77/149 (51%), Gaps = 1/149 (0%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-P 423
T+ NS + L IF + +++E+ + +N +L + VFSNL L+ L L + I + P
Sbjct: 275 TLFGNSLKELSLGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISP 334
Query: 422 EEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETF 243
F + LR LSL N L+ L +V R L +++L N + +L +FA++ L
Sbjct: 335 GAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAI 394
Query: 242 VMDGNELQVLPDSLFSGLRNLTTVSLRNN 156
+ N+L+ LP +F L L + L +N
Sbjct: 395 QLQNNQLENLPLGIFDHLGKLCELRLYDN 423
Score = 59.7 bits (138), Expect = 8e-09
Identities = 35/122 (28%), Positives = 60/122 (49%)
Frame = -3
Query: 392 TLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVL 213
+L + + L S + L +L + N ++ + P F +L +L + N+LQVL
Sbjct: 57 SLQILNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVL 116
Query: 212 PDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLH 33
P LF GL +L ++ L +N++ I F ++++ L L N L + PD + L L
Sbjct: 117 PIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLT 176
Query: 32 KL 27
KL
Sbjct: 177 KL 178
Score = 52.4 bits (120), Expect = 1e-06
Identities = 32/99 (32%), Positives = 51/99 (51%)
Frame = -3
Query: 320 SLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVI 141
SL + + EL F ++ AL ++ NEL + F L +L +SL NNK+ V+
Sbjct: 57 SLQILNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVL 116
Query: 140 SMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
+ FQG S+ +L LS N+L + +S + L +LQ
Sbjct: 117 PIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQ 155
>AF061444-1|AAC77911.1| 907|Homo sapiens G protein-coupled receptor
LGR5 protein.
Length = 907
Score = 89.8 bits (213), Expect = 6e-18
Identities = 52/175 (29%), Positives = 90/175 (51%), Gaps = 1/175 (0%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARN 372
L ++E++++ N + + F+ L +L+ L L + +R +P E + N L++L L N
Sbjct: 89 LHFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDAN 148
Query: 371 QLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSG 192
+ +P S G L L L NA+ E+ + F L AL+ + N++ +PD F
Sbjct: 149 HISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGN 208
Query: 191 LRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
L + + L NN+I + F G S+ TLDL+YN L P ++ + L+ L +L
Sbjct: 209 LSSWVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRT-LSNLKEL 262
Score = 72.9 bits (171), Expect = 8e-13
Identities = 60/196 (30%), Positives = 94/196 (47%), Gaps = 1/196 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLD-LSSIRELPEEFI 411
N+ R + + F G + I +N + + F +LP LRTL L+ S I E P +
Sbjct: 267 NNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFP-DLT 325
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
+ L +L+L Q+ +LP++V L L LSYN + +L F+ + L+ +
Sbjct: 326 GTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS--FSVCQKLQKIDLRH 383
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
NE+ + F L +L +++L NKI++I N F S+ LDLS N L+
Sbjct: 384 NEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLS------SF 437
Query: 50 PLNQLHKLQTLTLAWN 3
P+ LH L L L N
Sbjct: 438 PITGLHGLTHLKLTGN 453
Score = 70.5 bits (165), Expect = 4e-12
Identities = 43/149 (28%), Positives = 76/149 (51%), Gaps = 2/149 (1%)
Frame = -3
Query: 482 SNLPALRT-LQLDLSSIREL-PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTL 309
SNL + L L +++I +L P S L L LA N L +P+ G L L L
Sbjct: 62 SNLSVFTSYLDLSMNNISQLLPNPLPSLHFLEELRLAGNALTYIPKGAFTGLYSLKVLML 121
Query: 308 SYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNT 129
N + + E +LR+L++ +D N + +P S FSGL +L + L +N ++ I +
Sbjct: 122 QNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQA 181
Query: 128 FQGATSIRTLDLSYNRLAFAPDSLYSPLN 42
F+ ++++ + L+ N++ PD + L+
Sbjct: 182 FRSLSALQAMTLALNKIHHIPDYAFGNLS 210
Score = 69.7 bits (163), Expect = 7e-12
Identities = 54/178 (30%), Positives = 92/178 (51%), Gaps = 2/178 (1%)
Frame = -3
Query: 554 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSL- 381
R L +++E+ +N ++ E F P+L T+ + I+ + + P LRTL+L
Sbjct: 254 RTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLN 313
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSL 201
+Q+ P L G L SLTL+ ++ L + L L+ + N L+ LP
Sbjct: 314 GASQITEFPD--LTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS-- 369
Query: 200 FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
FS + L + LR+N+I I ++TFQ S+R+L+L++N++A + +S L L KL
Sbjct: 370 FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKL 427
Score = 61.3 bits (142), Expect = 3e-09
Identities = 31/97 (31%), Positives = 51/97 (52%)
Frame = -3
Query: 317 LTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVIS 138
L LS N +++L P L LE + GN L +P F+GL +L + L+NN++ +
Sbjct: 71 LDLSMNNISQLLPNPLPSLHFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 137 MNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
Q S+++L L N +++ P S +S L+ L L
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHL 167
Score = 54.0 bits (124), Expect = 4e-07
Identities = 39/129 (30%), Positives = 60/129 (46%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
L L+ N + L + L L L L+ NA+ + F L +L+ ++ N+L+ +P
Sbjct: 71 LDLSMNNISQLLPNPLPSLHFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHK 30
LR+L ++ L N IS + + F G S+R L L N L P + L
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAF---RSLSA 187
Query: 29 LQTLTLAWN 3
LQ +TLA N
Sbjct: 188 LQAMTLALN 196
>BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 89.0 bits (211), Expect = 1e-17
Identities = 56/197 (28%), Positives = 100/197 (50%), Gaps = 1/197 (0%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EF 414
RN + ++F+ L +Q ++++ N + F L AL++L++ + + +L + F
Sbjct: 201 RNRISAIPPKMFK-LPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAF 259
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
S + L L N L + + L G L L LS NA+ ++P+ + + L +
Sbjct: 260 WGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLT 319
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
N L L DS F GL L T+ + NN++S I+ F+G +S++TLDL N +++ + +
Sbjct: 320 FNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMN 379
Query: 53 SPLNQLHKLQTLTLAWN 3
+ L KL+ L L N
Sbjct: 380 GAFSGLDKLRRLILQGN 396
Score = 68.1 bits (159), Expect = 2e-11
Identities = 53/198 (26%), Positives = 91/198 (45%), Gaps = 4/198 (2%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PE 420
M RN L F GL +++ +++ +N + + L L+ L L ++I + P+
Sbjct: 246 MQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPD 305
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+ L L L N L L S G + L +L + N V+ +A F L +L+T
Sbjct: 306 AWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLD 365
Query: 239 MDGNELQVLPDSL---FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFA 69
+ NE+ + + FSGL L + L+ N+I I+ F G ++ LDLS N +
Sbjct: 366 LKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSL 425
Query: 68 PDSLYSPLNQLHKLQTLT 15
+ +S + +L +L T
Sbjct: 426 QGNAFSQMKKLQQLHLNT 443
Score = 54.4 bits (125), Expect = 3e-07
Identities = 39/162 (24%), Positives = 72/162 (44%), Gaps = 4/162 (2%)
Frame = -3
Query: 551 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLAR 375
GL +QE+ +S N + + L L L + + L + F+ S L TL +
Sbjct: 285 GLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGN 344
Query: 374 NQLRALPRSVLRGQTQLTSLTLSYNAVAELAPEL---FADLRALETFVMDGNELQVLPDS 204
N++ + RG + L +L L N ++ ++ F+ L L ++ GN ++ +
Sbjct: 345 NRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKK 404
Query: 203 LFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
F+GL L + L +N I + N F ++ L L+ + L
Sbjct: 405 AFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSL 446
Score = 43.6 bits (98), Expect = 5e-04
Identities = 30/105 (28%), Positives = 54/105 (51%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
L +R +L LP + + + L LS+N ++ + + L++L ++ NEL+ +P
Sbjct: 58 LDCSRKRLARLPEPL---PSWVARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIP 114
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLA 75
+ L N+T +SL N+I I + S+ TLDLS N ++
Sbjct: 115 N-LGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNIS 158
>BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 89.0 bits (211), Expect = 1e-17
Identities = 56/197 (28%), Positives = 100/197 (50%), Gaps = 1/197 (0%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EF 414
RN + ++F+ L +Q ++++ N + F L AL++L++ + + +L + F
Sbjct: 201 RNRISAIPPKMFK-LPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAF 259
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
S + L L N L + + L G L L LS NA+ ++P+ + + L +
Sbjct: 260 WGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLT 319
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
N L L DS F GL L T+ + NN++S I+ F+G +S++TLDL N +++ + +
Sbjct: 320 FNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMN 379
Query: 53 SPLNQLHKLQTLTLAWN 3
+ L KL+ L L N
Sbjct: 380 GAFSGLDKLRRLILQGN 396
Score = 68.1 bits (159), Expect = 2e-11
Identities = 53/198 (26%), Positives = 91/198 (45%), Gaps = 4/198 (2%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PE 420
M RN L F GL +++ +++ +N + + L L+ L L ++I + P+
Sbjct: 246 MQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPD 305
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+ L L L N L L S G + L +L + N V+ +A F L +L+T
Sbjct: 306 AWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLD 365
Query: 239 MDGNELQVLPDSL---FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFA 69
+ NE+ + + FSGL L + L+ N+I I+ F G ++ LDLS N +
Sbjct: 366 LKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSL 425
Query: 68 PDSLYSPLNQLHKLQTLT 15
+ +S + +L +L T
Sbjct: 426 QGNAFSQMKKLQQLHLNT 443
Score = 54.4 bits (125), Expect = 3e-07
Identities = 39/162 (24%), Positives = 72/162 (44%), Gaps = 4/162 (2%)
Frame = -3
Query: 551 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLAR 375
GL +QE+ +S N + + L L L + + L + F+ S L TL +
Sbjct: 285 GLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGN 344
Query: 374 NQLRALPRSVLRGQTQLTSLTLSYNAVAELAPEL---FADLRALETFVMDGNELQVLPDS 204
N++ + RG + L +L L N ++ ++ F+ L L ++ GN ++ +
Sbjct: 345 NRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKK 404
Query: 203 LFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
F+GL L + L +N I + N F ++ L L+ + L
Sbjct: 405 AFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSL 446
Score = 43.6 bits (98), Expect = 5e-04
Identities = 30/105 (28%), Positives = 54/105 (51%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
L +R +L LP + + + L LS+N ++ + + L++L ++ NEL+ +P
Sbjct: 58 LDCSRKRLARLPEPL---PSWVARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIP 114
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLA 75
+ L N+T +SL N+I I + S+ TLDLS N ++
Sbjct: 115 N-LGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNIS 158
>AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 89.0 bits (211), Expect = 1e-17
Identities = 56/197 (28%), Positives = 100/197 (50%), Gaps = 1/197 (0%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EF 414
RN + ++F+ L +Q ++++ N + F L AL++L++ + + +L + F
Sbjct: 201 RNRISAIPPKMFK-LPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAF 259
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
S + L L N L + + L G L L LS NA+ ++P+ + + L +
Sbjct: 260 WGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLT 319
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
N L L DS F GL L T+ + NN++S I+ F+G +S++TLDL N +++ + +
Sbjct: 320 FNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMN 379
Query: 53 SPLNQLHKLQTLTLAWN 3
+ L KL+ L L N
Sbjct: 380 GAFSGLDKLRRLILQGN 396
Score = 68.1 bits (159), Expect = 2e-11
Identities = 53/198 (26%), Positives = 91/198 (45%), Gaps = 4/198 (2%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PE 420
M RN L F GL +++ +++ +N + + L L+ L L ++I + P+
Sbjct: 246 MQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPD 305
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+ L L L N L L S G + L +L + N V+ +A F L +L+T
Sbjct: 306 AWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLD 365
Query: 239 MDGNELQVLPDSL---FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFA 69
+ NE+ + + FSGL L + L+ N+I I+ F G ++ LDLS N +
Sbjct: 366 LKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSL 425
Query: 68 PDSLYSPLNQLHKLQTLT 15
+ +S + +L +L T
Sbjct: 426 QGNAFSQMKKLQQLHLNT 443
Score = 54.4 bits (125), Expect = 3e-07
Identities = 39/162 (24%), Positives = 72/162 (44%), Gaps = 4/162 (2%)
Frame = -3
Query: 551 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLAR 375
GL +QE+ +S N + + L L L + + L + F+ S L TL +
Sbjct: 285 GLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGN 344
Query: 374 NQLRALPRSVLRGQTQLTSLTLSYNAVAELAPEL---FADLRALETFVMDGNELQVLPDS 204
N++ + RG + L +L L N ++ ++ F+ L L ++ GN ++ +
Sbjct: 345 NRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKK 404
Query: 203 LFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
F+GL L + L +N I + N F ++ L L+ + L
Sbjct: 405 AFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSL 446
Score = 43.6 bits (98), Expect = 5e-04
Identities = 30/105 (28%), Positives = 54/105 (51%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
L +R +L LP + + + L LS+N ++ + + L++L ++ NEL+ +P
Sbjct: 58 LDCSRKRLARLPEPL---PSWVARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIP 114
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLA 75
+ L N+T +SL N+I I + S+ TLDLS N ++
Sbjct: 115 N-LGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNIS 158
>AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein.
Length = 1059
Score = 89.0 bits (211), Expect = 1e-17
Identities = 56/197 (28%), Positives = 100/197 (50%), Gaps = 1/197 (0%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EF 414
RN + ++F+ L +Q ++++ N + F L AL++L++ + + +L + F
Sbjct: 141 RNRISAIPPKMFK-LPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAF 199
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
S + L L N L + + L G L L LS NA+ ++P+ + + L +
Sbjct: 200 WGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLT 259
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
N L L DS F GL L T+ + NN++S I+ F+G +S++TLDL N +++ + +
Sbjct: 260 FNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMN 319
Query: 53 SPLNQLHKLQTLTLAWN 3
+ L KL+ L L N
Sbjct: 320 GAFSGLDKLRRLILQGN 336
Score = 68.1 bits (159), Expect = 2e-11
Identities = 53/198 (26%), Positives = 91/198 (45%), Gaps = 4/198 (2%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PE 420
M RN L F GL +++ +++ +N + + L L+ L L ++I + P+
Sbjct: 186 MQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPD 245
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+ L L L N L L S G + L +L + N V+ +A F L +L+T
Sbjct: 246 AWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLD 305
Query: 239 MDGNELQVLPDSL---FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFA 69
+ NE+ + + FSGL L + L+ N+I I+ F G ++ LDLS N +
Sbjct: 306 LKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSL 365
Query: 68 PDSLYSPLNQLHKLQTLT 15
+ +S + +L +L T
Sbjct: 366 QGNAFSQMKKLQQLHLNT 383
Score = 54.4 bits (125), Expect = 3e-07
Identities = 39/162 (24%), Positives = 72/162 (44%), Gaps = 4/162 (2%)
Frame = -3
Query: 551 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLAR 375
GL +QE+ +S N + + L L L + + L + F+ S L TL +
Sbjct: 225 GLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGN 284
Query: 374 NQLRALPRSVLRGQTQLTSLTLSYNAVAELAPEL---FADLRALETFVMDGNELQVLPDS 204
N++ + RG + L +L L N ++ ++ F+ L L ++ GN ++ +
Sbjct: 285 NRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKK 344
Query: 203 LFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
F+GL L + L +N I + N F ++ L L+ + L
Sbjct: 345 AFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSL 386
Score = 39.9 bits (89), Expect = 0.007
Identities = 24/79 (30%), Positives = 43/79 (54%)
Frame = -3
Query: 311 LSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMN 132
LS+N ++ + + L++L ++ NEL+ +P+ L N+T +SL N+I I
Sbjct: 21 LSHNRLSFIKASSMSHLQSLREVKLNNNELETIPN-LGPVSANITLLSLAGNRIVEILPE 79
Query: 131 TFQGATSIRTLDLSYNRLA 75
+ S+ TLDLS N ++
Sbjct: 80 HLKEFQSLETLDLSSNNIS 98
>AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein.
Length = 1119
Score = 89.0 bits (211), Expect = 1e-17
Identities = 56/197 (28%), Positives = 100/197 (50%), Gaps = 1/197 (0%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EF 414
RN + ++F+ L +Q ++++ N + F L AL++L++ + + +L + F
Sbjct: 201 RNRISAIPPKMFK-LPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAF 259
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
S + L L N L + + L G L L LS NA+ ++P+ + + L +
Sbjct: 260 WGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLT 319
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
N L L DS F GL L T+ + NN++S I+ F+G +S++TLDL N +++ + +
Sbjct: 320 FNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMN 379
Query: 53 SPLNQLHKLQTLTLAWN 3
+ L KL+ L L N
Sbjct: 380 GAFSGLDKLRRLILQGN 396
Score = 68.1 bits (159), Expect = 2e-11
Identities = 53/198 (26%), Positives = 91/198 (45%), Gaps = 4/198 (2%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PE 420
M RN L F GL +++ +++ +N + + L L+ L L ++I + P+
Sbjct: 246 MQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPD 305
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+ L L L N L L S G + L +L + N V+ +A F L +L+T
Sbjct: 306 AWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLD 365
Query: 239 MDGNELQVLPDSL---FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFA 69
+ NE+ + + FSGL L + L+ N+I I+ F G ++ LDLS N +
Sbjct: 366 LKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSL 425
Query: 68 PDSLYSPLNQLHKLQTLT 15
+ +S + +L +L T
Sbjct: 426 QGNAFSQMKKLQQLHLNT 443
Score = 54.4 bits (125), Expect = 3e-07
Identities = 39/162 (24%), Positives = 72/162 (44%), Gaps = 4/162 (2%)
Frame = -3
Query: 551 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLAR 375
GL +QE+ +S N + + L L L + + L + F+ S L TL +
Sbjct: 285 GLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGN 344
Query: 374 NQLRALPRSVLRGQTQLTSLTLSYNAVAELAPEL---FADLRALETFVMDGNELQVLPDS 204
N++ + RG + L +L L N ++ ++ F+ L L ++ GN ++ +
Sbjct: 345 NRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKK 404
Query: 203 LFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
F+GL L + L +N I + N F ++ L L+ + L
Sbjct: 405 AFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSL 446
Score = 43.6 bits (98), Expect = 5e-04
Identities = 30/105 (28%), Positives = 54/105 (51%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
L +R +L LP + + + L LS+N ++ + + L++L ++ NEL+ +P
Sbjct: 58 LDCSRKRLARLPEPL---PSWVARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIP 114
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLA 75
+ L N+T +SL N+I I + S+ TLDLS N ++
Sbjct: 115 N-LGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNIS 158
>BC047905-1|AAH47905.2| 915|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 915
Score = 88.2 bits (209), Expect = 2e-17
Identities = 54/188 (28%), Positives = 96/188 (51%), Gaps = 1/188 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N+ L +F L ++E+++S N + FS L +L+ L L + + +P E +
Sbjct: 24 NNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALW 83
Query: 407 NSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
P L++L L N + +P G + L L L NA+ E+ +L AL+ +
Sbjct: 84 ELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLAL 143
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N + +PD F L +L + L NN+I + ++F+G ++ TLDL+YN+L P ++ +
Sbjct: 144 NRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRT 203
Query: 50 PLNQLHKL 27
L +L +L
Sbjct: 204 -LGRLQEL 210
Score = 61.3 bits (142), Expect = 3e-09
Identities = 50/178 (28%), Positives = 81/178 (45%), Gaps = 2/178 (1%)
Frame = -3
Query: 554 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSL- 381
R L +QE+ NN + E F P L+T+ + I+ + P L TLSL
Sbjct: 202 RTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLN 261
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSL 201
++ P L+G T L LTL+ + L + L L + N+++ LP
Sbjct: 262 GAMDIQEFPD--LKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPS-- 317
Query: 200 FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+ L + L++N+I I +TF +S++ LDLS+N + +S L+ L KL
Sbjct: 318 LHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKL 375
Score = 60.1 bits (139), Expect = 6e-09
Identities = 33/100 (33%), Positives = 52/100 (52%)
Frame = -3
Query: 326 LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKIS 147
+++ LS N + EL P LF LR LE + GN L +P FSGL +L + L+NN++
Sbjct: 16 ISARDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLG 75
Query: 146 VISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
I S+++L L N ++ P+ + L+ L L
Sbjct: 76 GIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHL 115
Score = 58.8 bits (136), Expect = 1e-08
Identities = 47/200 (23%), Positives = 85/200 (42%), Gaps = 1/200 (0%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE 420
T+ N ++ F+ L + + + NN L F L L TL L+ + ++E P
Sbjct: 140 TLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPV 199
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+ L+ L N ++A+P G L ++ N + + F L L T
Sbjct: 200 AIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLS 259
Query: 239 MDG-NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPD 63
++G ++Q PD G +L ++L I ++ Q +R L+LS+N++ P
Sbjct: 260 LNGAMDIQEFPD--LKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPS 317
Query: 62 SLYSPLNQLHKLQTLTLAWN 3
L++ KL+ + L N
Sbjct: 318 -----LHRCQKLEEIGLQHN 332
Score = 54.4 bits (125), Expect = 3e-07
Identities = 39/127 (30%), Positives = 62/127 (48%)
Frame = -3
Query: 383 LARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDS 204
L+ N L L + L L LS N ++ + + F+ L +L+ ++ N+L +P
Sbjct: 21 LSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAE 80
Query: 203 LFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
L +L ++ L N IS++ +F+G +S+R L L N L P LN L LQ
Sbjct: 81 ALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIP---VRALNNLPALQ 137
Query: 23 TLTLAWN 3
+TLA N
Sbjct: 138 AMTLALN 144
Score = 51.6 bits (118), Expect = 2e-06
Identities = 37/138 (26%), Positives = 63/138 (45%)
Frame = -3
Query: 500 LKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLT 321
L + LP LR L+L + I ELP L + L N++ + + L
Sbjct: 291 LPSGMCQQLPRLRVLELSHNQIEELPSLHRCQK-LEEIGLQHNRIWEIGADTFSQLSSLQ 349
Query: 320 SLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVI 141
+L LS+NA+ + PE F+ L +L + N+L LP +GL L + L+ N +++
Sbjct: 350 ALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLP---LAGLGGLMHLKLKGN-LALS 405
Query: 140 SMNTFQGATSIRTLDLSY 87
+ +R L++ Y
Sbjct: 406 QAFSKDSFPKLRILEVPY 423
>AY358119-1|AAQ88486.1| 915|Homo sapiens gonadotropin receptor
protein.
Length = 915
Score = 88.2 bits (209), Expect = 2e-17
Identities = 54/188 (28%), Positives = 96/188 (51%), Gaps = 1/188 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N+ L +F L ++E+++S N + FS L +L+ L L + + +P E +
Sbjct: 24 NNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALW 83
Query: 407 NSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
P L++L L N + +P G + L L L NA+ E+ +L AL+ +
Sbjct: 84 ELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLAL 143
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N + +PD F L +L + L NN+I + ++F+G ++ TLDL+YN+L P ++ +
Sbjct: 144 NRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRT 203
Query: 50 PLNQLHKL 27
L +L +L
Sbjct: 204 -LGRLQEL 210
Score = 61.3 bits (142), Expect = 3e-09
Identities = 50/178 (28%), Positives = 81/178 (45%), Gaps = 2/178 (1%)
Frame = -3
Query: 554 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSL- 381
R L +QE+ NN + E F P L+T+ + I+ + P L TLSL
Sbjct: 202 RTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLN 261
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSL 201
++ P L+G T L LTL+ + L + L L + N+++ LP
Sbjct: 262 GAMDIQEFPD--LKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPS-- 317
Query: 200 FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+ L + L++N+I I +TF +S++ LDLS+N + +S L+ L KL
Sbjct: 318 LHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKL 375
Score = 60.1 bits (139), Expect = 6e-09
Identities = 33/100 (33%), Positives = 52/100 (52%)
Frame = -3
Query: 326 LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKIS 147
+++ LS N + EL P LF LR LE + GN L +P FSGL +L + L+NN++
Sbjct: 16 ISARDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLG 75
Query: 146 VISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
I S+++L L N ++ P+ + L+ L L
Sbjct: 76 GIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHL 115
Score = 58.8 bits (136), Expect = 1e-08
Identities = 47/200 (23%), Positives = 85/200 (42%), Gaps = 1/200 (0%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE 420
T+ N ++ F+ L + + + NN L F L L TL L+ + ++E P
Sbjct: 140 TLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPV 199
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+ L+ L N ++A+P G L ++ N + + F L L T
Sbjct: 200 AIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLS 259
Query: 239 MDG-NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPD 63
++G ++Q PD G +L ++L I ++ Q +R L+LS+N++ P
Sbjct: 260 LNGAMDIQEFPD--LKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPS 317
Query: 62 SLYSPLNQLHKLQTLTLAWN 3
L++ KL+ + L N
Sbjct: 318 -----LHRCQKLEEIGLQHN 332
Score = 54.4 bits (125), Expect = 3e-07
Identities = 39/127 (30%), Positives = 62/127 (48%)
Frame = -3
Query: 383 LARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDS 204
L+ N L L + L L LS N ++ + + F+ L +L+ ++ N+L +P
Sbjct: 21 LSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAE 80
Query: 203 LFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
L +L ++ L N IS++ +F+G +S+R L L N L P LN L LQ
Sbjct: 81 ALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIP---VRALNNLPALQ 137
Query: 23 TLTLAWN 3
+TLA N
Sbjct: 138 AMTLALN 144
Score = 51.6 bits (118), Expect = 2e-06
Identities = 37/138 (26%), Positives = 63/138 (45%)
Frame = -3
Query: 500 LKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLT 321
L + LP LR L+L + I ELP L + L N++ + + L
Sbjct: 291 LPSGMCQQLPRLRVLELSHNQIEELPSLHRCQK-LEEIGLQHNRIWEIGADTFSQLSSLQ 349
Query: 320 SLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVI 141
+L LS+NA+ + PE F+ L +L + N+L LP +GL L + L+ N +++
Sbjct: 350 ALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLP---LAGLGGLMHLKLKGN-LALS 405
Query: 140 SMNTFQGATSIRTLDLSY 87
+ +R L++ Y
Sbjct: 406 QAFSKDSFPKLRILEVPY 423
>AL356953-3|CAI15929.1| 915|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 915
Score = 88.2 bits (209), Expect = 2e-17
Identities = 54/188 (28%), Positives = 96/188 (51%), Gaps = 1/188 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N+ L +F L ++E+++S N + FS L +L+ L L + + +P E +
Sbjct: 24 NNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALW 83
Query: 407 NSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
P L++L L N + +P G + L L L NA+ E+ +L AL+ +
Sbjct: 84 ELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLAL 143
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N + +PD F L +L + L NN+I + ++F+G ++ TLDL+YN+L P ++ +
Sbjct: 144 NRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRT 203
Query: 50 PLNQLHKL 27
L +L +L
Sbjct: 204 -LGRLQEL 210
Score = 61.3 bits (142), Expect = 3e-09
Identities = 50/178 (28%), Positives = 81/178 (45%), Gaps = 2/178 (1%)
Frame = -3
Query: 554 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSL- 381
R L +QE+ NN + E F P L+T+ + I+ + P L TLSL
Sbjct: 202 RTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLN 261
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSL 201
++ P L+G T L LTL+ + L + L L + N+++ LP
Sbjct: 262 GAMDIQEFPD--LKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPS-- 317
Query: 200 FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+ L + L++N+I I +TF +S++ LDLS+N + +S L+ L KL
Sbjct: 318 LHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKL 375
Score = 60.1 bits (139), Expect = 6e-09
Identities = 33/100 (33%), Positives = 52/100 (52%)
Frame = -3
Query: 326 LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKIS 147
+++ LS N + EL P LF LR LE + GN L +P FSGL +L + L+NN++
Sbjct: 16 ISARDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLG 75
Query: 146 VISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
I S+++L L N ++ P+ + L+ L L
Sbjct: 76 GIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHL 115
Score = 58.8 bits (136), Expect = 1e-08
Identities = 47/200 (23%), Positives = 85/200 (42%), Gaps = 1/200 (0%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE 420
T+ N ++ F+ L + + + NN L F L L TL L+ + ++E P
Sbjct: 140 TLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPV 199
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+ L+ L N ++A+P G L ++ N + + F L L T
Sbjct: 200 AIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLS 259
Query: 239 MDG-NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPD 63
++G ++Q PD G +L ++L I ++ Q +R L+LS+N++ P
Sbjct: 260 LNGAMDIQEFPD--LKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPS 317
Query: 62 SLYSPLNQLHKLQTLTLAWN 3
L++ KL+ + L N
Sbjct: 318 -----LHRCQKLEEIGLQHN 332
Score = 54.4 bits (125), Expect = 3e-07
Identities = 39/127 (30%), Positives = 62/127 (48%)
Frame = -3
Query: 383 LARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDS 204
L+ N L L + L L LS N ++ + + F+ L +L+ ++ N+L +P
Sbjct: 21 LSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAE 80
Query: 203 LFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
L +L ++ L N IS++ +F+G +S+R L L N L P LN L LQ
Sbjct: 81 ALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIP---VRALNNLPALQ 137
Query: 23 TLTLAWN 3
+TLA N
Sbjct: 138 AMTLALN 144
Score = 51.6 bits (118), Expect = 2e-06
Identities = 37/138 (26%), Positives = 63/138 (45%)
Frame = -3
Query: 500 LKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLT 321
L + LP LR L+L + I ELP L + L N++ + + L
Sbjct: 291 LPSGMCQQLPRLRVLELSHNQIEELPSLHRCQK-LEEIGLQHNRIWEIGADTFSQLSSLQ 349
Query: 320 SLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVI 141
+L LS+NA+ + PE F+ L +L + N+L LP +GL L + L+ N +++
Sbjct: 350 ALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLP---LAGLGGLMHLKLKGN-LALS 405
Query: 140 SMNTFQGATSIRTLDLSY 87
+ +R L++ Y
Sbjct: 406 QAFSKDSFPKLRILEVPY 423
>AL356953-1|CAI15927.1| 967|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 967
Score = 88.2 bits (209), Expect = 2e-17
Identities = 54/188 (28%), Positives = 96/188 (51%), Gaps = 1/188 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N+ L +F L ++E+++S N + FS L +L+ L L + + +P E +
Sbjct: 76 NNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALW 135
Query: 407 NSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
P L++L L N + +P G + L L L NA+ E+ +L AL+ +
Sbjct: 136 ELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLAL 195
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N + +PD F L +L + L NN+I + ++F+G ++ TLDL+YN+L P ++ +
Sbjct: 196 NRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRT 255
Query: 50 PLNQLHKL 27
L +L +L
Sbjct: 256 -LGRLQEL 262
Score = 61.3 bits (142), Expect = 3e-09
Identities = 50/178 (28%), Positives = 81/178 (45%), Gaps = 2/178 (1%)
Frame = -3
Query: 554 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSL- 381
R L +QE+ NN + E F P L+T+ + I+ + P L TLSL
Sbjct: 254 RTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLN 313
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSL 201
++ P L+G T L LTL+ + L + L L + N+++ LP
Sbjct: 314 GAMDIQEFPD--LKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPS-- 369
Query: 200 FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+ L + L++N+I I +TF +S++ LDLS+N + +S L+ L KL
Sbjct: 370 LHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKL 427
Score = 60.9 bits (141), Expect = 3e-09
Identities = 34/97 (35%), Positives = 50/97 (51%)
Frame = -3
Query: 317 LTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVIS 138
L LS N + EL P LF LR LE + GN L +P FSGL +L + L+NN++ I
Sbjct: 71 LDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIP 130
Query: 137 MNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
S+++L L N ++ P+ + L+ L L
Sbjct: 131 AEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHL 167
Score = 58.8 bits (136), Expect = 1e-08
Identities = 47/200 (23%), Positives = 85/200 (42%), Gaps = 1/200 (0%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE 420
T+ N ++ F+ L + + + NN L F L L TL L+ + ++E P
Sbjct: 192 TLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPV 251
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+ L+ L N ++A+P G L ++ N + + F L L T
Sbjct: 252 AIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLS 311
Query: 239 MDG-NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPD 63
++G ++Q PD G +L ++L I ++ Q +R L+LS+N++ P
Sbjct: 312 LNGAMDIQEFPD--LKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPS 369
Query: 62 SLYSPLNQLHKLQTLTLAWN 3
L++ KL+ + L N
Sbjct: 370 -----LHRCQKLEEIGLQHN 384
Score = 56.0 bits (129), Expect = 1e-07
Identities = 40/129 (31%), Positives = 63/129 (48%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
L L+ N L L + L L LS N ++ + + F+ L +L+ ++ N+L +P
Sbjct: 71 LDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIP 130
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHK 30
L +L ++ L N IS++ +F+G +S+R L L N L P LN L
Sbjct: 131 AEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIP---VRALNNLPA 187
Query: 29 LQTLTLAWN 3
LQ +TLA N
Sbjct: 188 LQAMTLALN 196
Score = 51.6 bits (118), Expect = 2e-06
Identities = 37/138 (26%), Positives = 63/138 (45%)
Frame = -3
Query: 500 LKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLT 321
L + LP LR L+L + I ELP L + L N++ + + L
Sbjct: 343 LPSGMCQQLPRLRVLELSHNQIEELPSLHRCQK-LEEIGLQHNRIWEIGADTFSQLSSLQ 401
Query: 320 SLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVI 141
+L LS+NA+ + PE F+ L +L + N+L LP +GL L + L+ N +++
Sbjct: 402 ALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLP---LAGLGGLMHLKLKGN-LALS 457
Query: 140 SMNTFQGATSIRTLDLSY 87
+ +R L++ Y
Sbjct: 458 QAFSKDSFPKLRILEVPY 475
>AB049405-1|BAB39854.1| 928|Homo sapiens VTS20631 protein.
Length = 928
Score = 88.2 bits (209), Expect = 2e-17
Identities = 54/188 (28%), Positives = 96/188 (51%), Gaps = 1/188 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N+ L +F L ++E+++S N + FS L +L+ L L + + +P E +
Sbjct: 37 NNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALW 96
Query: 407 NSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
P L++L L N + +P G + L L L NA+ E+ +L AL+ +
Sbjct: 97 ELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLAL 156
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N + +PD F L +L + L NN+I + ++F+G ++ TLDL+YN+L P ++ +
Sbjct: 157 NRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRT 216
Query: 50 PLNQLHKL 27
L +L +L
Sbjct: 217 -LGRLQEL 223
Score = 61.3 bits (142), Expect = 3e-09
Identities = 50/178 (28%), Positives = 81/178 (45%), Gaps = 2/178 (1%)
Frame = -3
Query: 554 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSL- 381
R L +QE+ NN + E F P L+T+ + I+ + P L TLSL
Sbjct: 215 RTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLN 274
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSL 201
++ P L+G T L LTL+ + L + L L + N+++ LP
Sbjct: 275 GAMDIQEFPD--LKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPS-- 330
Query: 200 FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+ L + L++N+I I +TF +S++ LDLS+N + +S L+ L KL
Sbjct: 331 LHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKL 388
Score = 60.9 bits (141), Expect = 3e-09
Identities = 34/97 (35%), Positives = 50/97 (51%)
Frame = -3
Query: 317 LTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVIS 138
L LS N + EL P LF LR LE + GN L +P FSGL +L + L+NN++ I
Sbjct: 32 LDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIP 91
Query: 137 MNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
S+++L L N ++ P+ + L+ L L
Sbjct: 92 AEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHL 128
Score = 58.8 bits (136), Expect = 1e-08
Identities = 47/200 (23%), Positives = 85/200 (42%), Gaps = 1/200 (0%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE 420
T+ N ++ F+ L + + + NN L F L L TL L+ + ++E P
Sbjct: 153 TLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPV 212
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+ L+ L N ++A+P G L ++ N + + F L L T
Sbjct: 213 AIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLS 272
Query: 239 MDG-NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPD 63
++G ++Q PD G +L ++L I ++ Q +R L+LS+N++ P
Sbjct: 273 LNGAMDIQEFPD--LKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPS 330
Query: 62 SLYSPLNQLHKLQTLTLAWN 3
L++ KL+ + L N
Sbjct: 331 -----LHRCQKLEEIGLQHN 345
Score = 56.0 bits (129), Expect = 1e-07
Identities = 40/129 (31%), Positives = 63/129 (48%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
L L+ N L L + L L LS N ++ + + F+ L +L+ ++ N+L +P
Sbjct: 32 LDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIP 91
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHK 30
L +L ++ L N IS++ +F+G +S+R L L N L P LN L
Sbjct: 92 AEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIP---VRALNNLPA 148
Query: 29 LQTLTLAWN 3
LQ +TLA N
Sbjct: 149 LQAMTLALN 157
Score = 51.6 bits (118), Expect = 2e-06
Identities = 37/138 (26%), Positives = 63/138 (45%)
Frame = -3
Query: 500 LKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLT 321
L + LP LR L+L + I ELP L + L N++ + + L
Sbjct: 304 LPSGMCQQLPRLRVLELSHNQIEELPSLHRCQK-LEEIGLQHNRIWEIGADTFSQLSSLQ 362
Query: 320 SLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVI 141
+L LS+NA+ + PE F+ L +L + N+L LP +GL L + L+ N +++
Sbjct: 363 ALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLP---LAGLGGLMHLKLKGN-LALS 418
Query: 140 SMNTFQGATSIRTLDLSY 87
+ +R L++ Y
Sbjct: 419 QAFSKDSFPKLRILEVPY 436
>AY358733-1|AAQ89095.1| 622|Homo sapiens CGLQ1891 protein.
Length = 622
Score = 86.2 bits (204), Expect = 8e-17
Identities = 57/199 (28%), Positives = 98/199 (49%), Gaps = 2/199 (1%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ RN L S F G+ ++ + +SNN L + E+ F +L L L L +++ ++P
Sbjct: 163 LQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSN 222
Query: 416 -FISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
F LR LSL+ N + A+ +G L L L + + + + F+ + L+ +
Sbjct: 223 AFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLI 282
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQG-ATSIRTLDLSYNRLAFAPD 63
+ N+L+ L FS L+NL + L N+I I +TF+ S++ L+LS+N L
Sbjct: 283 LSHNDLENLNSDTFSLLKNLIYLKLDRNRIISIDNDTFENMGASLKILNLSFNNLTALHP 342
Query: 62 SLYSPLNQLHKLQTLTLAW 6
+ PL+ L LQ + W
Sbjct: 343 RVLKPLSSLIHLQANSNPW 361
Score = 73.3 bits (172), Expect = 6e-13
Identities = 49/191 (25%), Positives = 92/191 (48%), Gaps = 2/191 (1%)
Frame = -3
Query: 602 FTMMRNSF-RYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL 426
F + N+F + LD IF+GL +++ + + N + VF++L +++ L L + + L
Sbjct: 112 FLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVL 171
Query: 425 PE-EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALE 249
F+ LR L L+ N + + S + L L L N + ++ F L++L
Sbjct: 172 GSGTFVGMVALRILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLR 231
Query: 248 TFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFA 69
+ N ++ + F GL NL + L+N++I ++ + F G +++ L LS+N L
Sbjct: 232 RLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENL 291
Query: 68 PDSLYSPLNQL 36
+S L L
Sbjct: 292 NSDTFSLLKNL 302
Score = 66.1 bits (154), Expect = 9e-11
Identities = 49/196 (25%), Positives = 86/196 (43%), Gaps = 1/196 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FI 411
N ++ +F L +Q + + N L F + ALR L L ++I + E F
Sbjct: 142 NQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQ 201
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L L L N L +P + L L+LS+N + + P F L LE ++
Sbjct: 202 HLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKN 261
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
+ ++ + FSG+ NL + L +N + ++ +TF ++ L L NR+ + +
Sbjct: 262 SRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNRIISIDNDTFE 321
Query: 50 PLNQLHKLQTLTLAWN 3
N L+ L L++N
Sbjct: 322 --NMGASLKILNLSFN 335
Score = 54.4 bits (125), Expect = 3e-07
Identities = 38/125 (30%), Positives = 61/125 (48%)
Frame = -3
Query: 452 LDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPEL 273
L LSSI P+ F ++ L L N + + S L G L +L L + + + P+
Sbjct: 49 LGLSSI---PKNFPESTVF--LYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPKA 103
Query: 272 FADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDL 93
F LR L ++ N ++ L +F GL NL + L+ N++S + F S++ L+L
Sbjct: 104 FVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNL 163
Query: 92 SYNRL 78
NRL
Sbjct: 164 QRNRL 168
Score = 44.4 bits (100), Expect = 3e-04
Identities = 29/105 (27%), Positives = 50/105 (47%)
Frame = -3
Query: 317 LTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVIS 138
L L+ N ++ + L +L +D + + + F LR+L + L NN I +
Sbjct: 65 LYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLD 124
Query: 137 MNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
F+G ++R L L YN+++F P ++ N L +Q L L N
Sbjct: 125 PGIFKGLLNLRNLYLQYNQVSFVPRGVF---NDLVSVQYLNLQRN 166
>AY280614-1|AAP36706.1| 622|Homo sapiens synleurin protein.
Length = 622
Score = 86.2 bits (204), Expect = 8e-17
Identities = 57/199 (28%), Positives = 98/199 (49%), Gaps = 2/199 (1%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ RN L S F G+ ++ + +SNN L + E+ F +L L L L +++ ++P
Sbjct: 163 LQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSN 222
Query: 416 -FISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
F LR LSL+ N + A+ +G L L L + + + + F+ + L+ +
Sbjct: 223 AFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLI 282
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQG-ATSIRTLDLSYNRLAFAPD 63
+ N+L+ L FS L+NL + L N+I I +TF+ S++ L+LS+N L
Sbjct: 283 LSHNDLENLNSDTFSLLKNLIYLKLDRNRIISIDNDTFENMGASLKILNLSFNNLTALHP 342
Query: 62 SLYSPLNQLHKLQTLTLAW 6
+ PL+ L LQ + W
Sbjct: 343 RVLKPLSSLIHLQANSNPW 361
Score = 73.3 bits (172), Expect = 6e-13
Identities = 49/191 (25%), Positives = 92/191 (48%), Gaps = 2/191 (1%)
Frame = -3
Query: 602 FTMMRNSF-RYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL 426
F + N+F + LD IF+GL +++ + + N + VF++L +++ L L + + L
Sbjct: 112 FLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVL 171
Query: 425 PE-EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALE 249
F+ LR L L+ N + + S + L L L N + ++ F L++L
Sbjct: 172 GSGTFVGMVALRILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLR 231
Query: 248 TFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFA 69
+ N ++ + F GL NL + L+N++I ++ + F G +++ L LS+N L
Sbjct: 232 RLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENL 291
Query: 68 PDSLYSPLNQL 36
+S L L
Sbjct: 292 NSDTFSLLKNL 302
Score = 66.1 bits (154), Expect = 9e-11
Identities = 49/196 (25%), Positives = 86/196 (43%), Gaps = 1/196 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FI 411
N ++ +F L +Q + + N L F + ALR L L ++I + E F
Sbjct: 142 NQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQ 201
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L L L N L +P + L L+LS+N + + P F L LE ++
Sbjct: 202 HLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKN 261
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
+ ++ + FSG+ NL + L +N + ++ +TF ++ L L NR+ + +
Sbjct: 262 SRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNRIISIDNDTFE 321
Query: 50 PLNQLHKLQTLTLAWN 3
N L+ L L++N
Sbjct: 322 --NMGASLKILNLSFN 335
Score = 54.4 bits (125), Expect = 3e-07
Identities = 38/125 (30%), Positives = 61/125 (48%)
Frame = -3
Query: 452 LDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPEL 273
L LSSI P+ F ++ L L N + + S L G L +L L + + + P+
Sbjct: 49 LGLSSI---PKNFPESTVF--LYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPKA 103
Query: 272 FADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDL 93
F LR L ++ N ++ L +F GL NL + L+ N++S + F S++ L+L
Sbjct: 104 FVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNL 163
Query: 92 SYNRL 78
NRL
Sbjct: 164 QRNRL 168
Score = 44.4 bits (100), Expect = 3e-04
Identities = 29/105 (27%), Positives = 50/105 (47%)
Frame = -3
Query: 317 LTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVIS 138
L L+ N ++ + L +L +D + + + F LR+L + L NN I +
Sbjct: 65 LYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLD 124
Query: 137 MNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
F+G ++R L L YN+++F P ++ N L +Q L L N
Sbjct: 125 PGIFKGLLNLRNLYLQYNQVSFVPRGVF---NDLVSVQYLNLQRN 166
>AK123022-1|BAC85517.1| 622|Homo sapiens protein ( Homo sapiens
cDNA FLJ41026 fis, clone BRAMY2004771, weakly similar
to CHONDROADHERIN PRECURSOR. ).
Length = 622
Score = 86.2 bits (204), Expect = 8e-17
Identities = 57/199 (28%), Positives = 98/199 (49%), Gaps = 2/199 (1%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ RN L S F G+ ++ + +SNN L + E+ F +L L L L +++ ++P
Sbjct: 163 LQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSN 222
Query: 416 -FISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
F LR LSL+ N + A+ +G L L L + + + + F+ + L+ +
Sbjct: 223 AFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLI 282
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQG-ATSIRTLDLSYNRLAFAPD 63
+ N+L+ L FS L+NL + L N+I I +TF+ S++ L+LS+N L
Sbjct: 283 LSHNDLENLNSDTFSLLKNLIYLKLDRNRIISIDNDTFENMGASLKILNLSFNNLTALHP 342
Query: 62 SLYSPLNQLHKLQTLTLAW 6
+ PL+ L LQ + W
Sbjct: 343 RVLKPLSSLIHLQANSNPW 361
Score = 73.3 bits (172), Expect = 6e-13
Identities = 49/191 (25%), Positives = 92/191 (48%), Gaps = 2/191 (1%)
Frame = -3
Query: 602 FTMMRNSF-RYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL 426
F + N+F + LD IF+GL +++ + + N + VF++L +++ L L + + L
Sbjct: 112 FLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVL 171
Query: 425 PE-EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALE 249
F+ LR L L+ N + + S + L L L N + ++ F L++L
Sbjct: 172 GSGTFVGMVALRILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLR 231
Query: 248 TFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFA 69
+ N ++ + F GL NL + L+N++I ++ + F G +++ L LS+N L
Sbjct: 232 RLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENL 291
Query: 68 PDSLYSPLNQL 36
+S L L
Sbjct: 292 NSDTFSLLKNL 302
Score = 66.1 bits (154), Expect = 9e-11
Identities = 49/196 (25%), Positives = 86/196 (43%), Gaps = 1/196 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FI 411
N ++ +F L +Q + + N L F + ALR L L ++I + E F
Sbjct: 142 NQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQ 201
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L L L N L +P + L L+LS+N + + P F L LE ++
Sbjct: 202 HLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKN 261
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
+ ++ + FSG+ NL + L +N + ++ +TF ++ L L NR+ + +
Sbjct: 262 SRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNRIISIDNDTFE 321
Query: 50 PLNQLHKLQTLTLAWN 3
N L+ L L++N
Sbjct: 322 --NMGASLKILNLSFN 335
Score = 54.4 bits (125), Expect = 3e-07
Identities = 38/125 (30%), Positives = 61/125 (48%)
Frame = -3
Query: 452 LDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPEL 273
L LSSI P+ F ++ L L N + + S L G L +L L + + + P+
Sbjct: 49 LGLSSI---PKNFPESTVF--LYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPKA 103
Query: 272 FADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDL 93
F LR L ++ N ++ L +F GL NL + L+ N++S + F S++ L+L
Sbjct: 104 FVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNL 163
Query: 92 SYNRL 78
NRL
Sbjct: 164 QRNRL 168
Score = 44.4 bits (100), Expect = 3e-04
Identities = 29/105 (27%), Positives = 50/105 (47%)
Frame = -3
Query: 317 LTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVIS 138
L L+ N ++ + L +L +D + + + F LR+L + L NN I +
Sbjct: 65 LYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLD 124
Query: 137 MNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
F+G ++R L L YN+++F P ++ N L +Q L L N
Sbjct: 125 PGIFKGLLNLRNLYLQYNQVSFVPRGVF---NDLVSVQYLNLQRN 166
>BC034389-1|AAH34389.1| 347|Homo sapiens leucine-rich
alpha-2-glycoprotein 1 protein.
Length = 347
Score = 85.4 bits (202), Expect = 1e-16
Identities = 58/184 (31%), Positives = 88/184 (47%), Gaps = 1/184 (0%)
Frame = -3
Query: 575 YLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSP 399
+L + + +G +QE+ +S+N +L +P LR L L +++ LP F +++
Sbjct: 82 HLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQASAT 141
Query: 398 LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 219
L TL L NQL L S L G L L LS N + +L P L A+ L T + N+L+
Sbjct: 142 LDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLE 201
Query: 218 VLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQ 39
LP L G L + L NK+ V+ + +R L L+ N+LA + L Q
Sbjct: 202 TLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQ 261
Query: 38 LHKL 27
L L
Sbjct: 262 LDML 265
Score = 83.8 bits (198), Expect = 4e-16
Identities = 56/184 (30%), Positives = 86/184 (46%), Gaps = 1/184 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N L E R + ++ + ++ N L +F L TL L + + L ++
Sbjct: 102 NGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQASATLDTLVLKENQLEVLEVSWLH 161
Query: 407 N-SPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L L L+ N+LR LP +L T L +L L N + L P+L LE ++G
Sbjct: 162 GLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQLERLHLEG 221
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N+LQVL L +L + L NK++ ++ FQG + LDLS N LA P+ L++
Sbjct: 222 NKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLASVPEGLWA 281
Query: 50 PLNQ 39
L Q
Sbjct: 282 SLGQ 285
Score = 65.3 bits (152), Expect = 2e-10
Identities = 43/135 (31%), Positives = 63/135 (46%), Gaps = 2/135 (1%)
Frame = -3
Query: 425 PEEFISNSPLRTLSLARN--QLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRAL 252
P E P T+ LA L LP ++L+G ++L L LS N + L+PE + L
Sbjct: 59 PAEIPGYLPADTVHLAVEFFNLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQL 118
Query: 251 ETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAF 72
+ N L LP LF L T+ L+ N++ V+ ++ G ++ LDLS NRL
Sbjct: 119 RVLDLTRNALTGLPSGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRK 178
Query: 71 APDSLYSPLNQLHKL 27
P L + L L
Sbjct: 179 LPPGLLANFTLLRTL 193
>AB073607-1|BAD38644.1| 347|Homo sapiens leucine-rich
alpha-2-glycoprotein protein.
Length = 347
Score = 85.4 bits (202), Expect = 1e-16
Identities = 58/184 (31%), Positives = 88/184 (47%), Gaps = 1/184 (0%)
Frame = -3
Query: 575 YLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSP 399
+L + + +G +QE+ +S+N +L +P LR L L +++ LP F +++
Sbjct: 82 HLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQASAT 141
Query: 398 LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 219
L TL L NQL L S L G L L LS N + +L P L A+ L T + N+L+
Sbjct: 142 LDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLE 201
Query: 218 VLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQ 39
LP L G L + L NK+ V+ + +R L L+ N+LA + L Q
Sbjct: 202 TLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQ 261
Query: 38 LHKL 27
L L
Sbjct: 262 LDML 265
Score = 83.8 bits (198), Expect = 4e-16
Identities = 56/184 (30%), Positives = 86/184 (46%), Gaps = 1/184 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N L E R + ++ + ++ N L +F L TL L + + L ++
Sbjct: 102 NGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQASATLDTLVLKENQLEVLEVSWLH 161
Query: 407 N-SPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L L L+ N+LR LP +L T L +L L N + L P+L LE ++G
Sbjct: 162 GLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQLERLHLEG 221
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N+LQVL L +L + L NK++ ++ FQG + LDLS N LA P+ L++
Sbjct: 222 NKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLASVPEGLWA 281
Query: 50 PLNQ 39
L Q
Sbjct: 282 SLGQ 285
Score = 65.3 bits (152), Expect = 2e-10
Identities = 43/135 (31%), Positives = 63/135 (46%), Gaps = 2/135 (1%)
Frame = -3
Query: 425 PEEFISNSPLRTLSLARN--QLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRAL 252
P E P T+ LA L LP ++L+G ++L L LS N + L+PE + L
Sbjct: 59 PAEIPGYLPADTVHLAVEFFNLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQL 118
Query: 251 ETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAF 72
+ N L LP LF L T+ L+ N++ V+ ++ G ++ LDLS NRL
Sbjct: 119 RVLDLTRNALTGLPSGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRK 178
Query: 71 APDSLYSPLNQLHKL 27
P L + L L
Sbjct: 179 LPPGLLANFTLLRTL 193
>BC070198-1|AAH70198.1| 347|Homo sapiens leucine-rich
alpha-2-glycoprotein 1 protein.
Length = 347
Score = 85.0 bits (201), Expect = 2e-16
Identities = 58/184 (31%), Positives = 88/184 (47%), Gaps = 1/184 (0%)
Frame = -3
Query: 575 YLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSP 399
+L + + +G +QE+ +S+N +L +P LR L L +++ LP F +++
Sbjct: 82 HLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQASAT 141
Query: 398 LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 219
L TL L NQL L S L G L L LS N + +L P L A+ L T + N+L+
Sbjct: 142 LDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLE 201
Query: 218 VLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQ 39
LP L G L + L NK+ V+ + +R L L+ N+LA + L Q
Sbjct: 202 TLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQ 261
Query: 38 LHKL 27
L L
Sbjct: 262 LDML 265
Score = 83.4 bits (197), Expect = 6e-16
Identities = 56/184 (30%), Positives = 86/184 (46%), Gaps = 1/184 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N L E R + ++ + ++ N L +F L TL L + + L ++
Sbjct: 102 NGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQASATLDTLVLKENQLEVLEVSWLH 161
Query: 407 N-SPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L L L+ N+LR LP +L T L +L L N + L P+L LE ++G
Sbjct: 162 GLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQLERLHLEG 221
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N+LQVL L +L + L NK++ ++ FQG + LDLS N LA P+ L++
Sbjct: 222 NKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLASVPEGLWA 281
Query: 50 PLNQ 39
L Q
Sbjct: 282 SLGQ 285
Score = 72.5 bits (170), Expect = 1e-12
Identities = 51/146 (34%), Positives = 73/146 (50%), Gaps = 2/146 (1%)
Frame = -3
Query: 458 LQLDLSSIRELPEEFISN-SPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELA 282
L ++ ++ LP + S L+ L L+ N L +L LR QL L L+ NA+ L
Sbjct: 73 LAVEFFNLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLP 132
Query: 281 PELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRT 102
P LF L+T V+ N+L+VL S GL+ L + L N++ + T +RT
Sbjct: 133 PGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRT 192
Query: 101 LDLSYNRL-AFAPDSLYSPLNQLHKL 27
LDL N+L PD L PL QL +L
Sbjct: 193 LDLGENQLETLPPDLLRGPL-QLERL 217
>AF403428-1|AAK95527.1| 347|Homo sapiens leucine-rich
alpha-2-glycoprotein protein.
Length = 347
Score = 85.0 bits (201), Expect = 2e-16
Identities = 58/184 (31%), Positives = 88/184 (47%), Gaps = 1/184 (0%)
Frame = -3
Query: 575 YLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSP 399
+L + + +G +QE+ +S+N +L +P LR L L +++ LP F +++
Sbjct: 82 HLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQASAT 141
Query: 398 LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 219
L TL L NQL L S L G L L LS N + +L P L A+ L T + N+L+
Sbjct: 142 LDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLE 201
Query: 218 VLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQ 39
LP L G L + L NK+ V+ + +R L L+ N+LA + L Q
Sbjct: 202 TLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQ 261
Query: 38 LHKL 27
L L
Sbjct: 262 LDML 265
Score = 83.4 bits (197), Expect = 6e-16
Identities = 56/184 (30%), Positives = 86/184 (46%), Gaps = 1/184 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N L E R + ++ + ++ N L +F L TL L + + L ++
Sbjct: 102 NGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQASATLDTLVLKENQLEVLEVSWLH 161
Query: 407 N-SPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L L L+ N+LR LP +L T L +L L N + L P+L LE ++G
Sbjct: 162 GLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQLERLHLEG 221
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N+LQVL L +L + L NK++ ++ FQG + LDLS N LA P+ L++
Sbjct: 222 NKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLASVPEGLWA 281
Query: 50 PLNQ 39
L Q
Sbjct: 282 SLGQ 285
Score = 72.5 bits (170), Expect = 1e-12
Identities = 51/146 (34%), Positives = 73/146 (50%), Gaps = 2/146 (1%)
Frame = -3
Query: 458 LQLDLSSIRELPEEFISN-SPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELA 282
L ++ ++ LP + S L+ L L+ N L +L LR QL L L+ NA+ L
Sbjct: 73 LAVEFFNLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLP 132
Query: 281 PELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRT 102
P LF L+T V+ N+L+VL S GL+ L + L N++ + T +RT
Sbjct: 133 PGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRT 192
Query: 101 LDLSYNRL-AFAPDSLYSPLNQLHKL 27
LDL N+L PD L PL QL +L
Sbjct: 193 LDLGENQLETLPPDLLRGPL-QLERL 217
>BC126410-1|AAI26411.1| 516|Homo sapiens leucine rich repeat
transmembrane neuronal 2 protein.
Length = 516
Score = 84.2 bits (199), Expect = 3e-16
Identities = 59/197 (29%), Positives = 97/197 (49%), Gaps = 6/197 (3%)
Frame = -3
Query: 575 YLDSEIFRGLDHIQE-----IKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-F 414
Y DS+ F + + + + + +N L+ F++ L L LD + I + E+ F
Sbjct: 46 YCDSQGFHSVPNATDKGSLGLSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAF 105
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
L+ L L+ N++ LP + L +L LS+N ++ L PELF LR L+T +
Sbjct: 106 QGLYKLKELILSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLR 165
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
N L+ +P LF R+L + L N++ ++ N F G +R L L +N+L + +
Sbjct: 166 SNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHF 225
Query: 53 SPLNQLHKLQTLTLAWN 3
L+ LH TL L WN
Sbjct: 226 LRLSSLH---TLFLQWN 239
Score = 66.9 bits (156), Expect = 5e-11
Identities = 51/171 (29%), Positives = 81/171 (47%), Gaps = 1/171 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFI 411
N + + F+GL ++E+ +S+N L F+ L L+ L L + + L PE F
Sbjct: 95 NQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFY 154
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L+TL L N LR +P + L L LS N + LA FA L L ++
Sbjct: 155 GLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEH 214
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
N+L + + F L +L T+ L+ NKIS ++ ++ LDL+ N +
Sbjct: 215 NQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEI 265
Score = 62.1 bits (144), Expect = 1e-09
Identities = 44/169 (26%), Positives = 77/169 (45%), Gaps = 1/169 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FI 411
N L E+F GL +Q + + +N T+ +F + +L L L + +R L F
Sbjct: 143 NQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFA 202
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
LR L L NQL + + + L +L L +N ++ L + LE + G
Sbjct: 203 GLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTG 262
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
NE++ + ++F + NL + + NNK++ + S+ T+ LS N
Sbjct: 263 NEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSGN 311
>BC126408-1|AAI26409.1| 516|Homo sapiens leucine rich repeat
transmembrane neuronal 2 protein.
Length = 516
Score = 84.2 bits (199), Expect = 3e-16
Identities = 59/197 (29%), Positives = 97/197 (49%), Gaps = 6/197 (3%)
Frame = -3
Query: 575 YLDSEIFRGLDHIQE-----IKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-F 414
Y DS+ F + + + + + +N L+ F++ L L LD + I + E+ F
Sbjct: 46 YCDSQGFHSVPNATDKGSLGLSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAF 105
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
L+ L L+ N++ LP + L +L LS+N ++ L PELF LR L+T +
Sbjct: 106 QGLYKLKELILSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLR 165
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
N L+ +P LF R+L + L N++ ++ N F G +R L L +N+L + +
Sbjct: 166 SNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHF 225
Query: 53 SPLNQLHKLQTLTLAWN 3
L+ LH TL L WN
Sbjct: 226 LRLSSLH---TLFLQWN 239
Score = 66.9 bits (156), Expect = 5e-11
Identities = 51/171 (29%), Positives = 81/171 (47%), Gaps = 1/171 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFI 411
N + + F+GL ++E+ +S+N L F+ L L+ L L + + L PE F
Sbjct: 95 NQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFY 154
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L+TL L N LR +P + L L LS N + LA FA L L ++
Sbjct: 155 GLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEH 214
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
N+L + + F L +L T+ L+ NKIS ++ ++ LDL+ N +
Sbjct: 215 NQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEI 265
Score = 62.1 bits (144), Expect = 1e-09
Identities = 44/169 (26%), Positives = 77/169 (45%), Gaps = 1/169 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FI 411
N L E+F GL +Q + + +N T+ +F + +L L L + +R L F
Sbjct: 143 NQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFA 202
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
LR L L NQL + + + L +L L +N ++ L + LE + G
Sbjct: 203 GLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTG 262
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
NE++ + ++F + NL + + NNK++ + S+ T+ LS N
Sbjct: 263 NEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSGN 311
>AY182026-1|AAO67547.1| 516|Homo sapiens leucine-rich repeat
transmembrane neuronal 2 protein protein.
Length = 516
Score = 84.2 bits (199), Expect = 3e-16
Identities = 59/197 (29%), Positives = 97/197 (49%), Gaps = 6/197 (3%)
Frame = -3
Query: 575 YLDSEIFRGLDHIQE-----IKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-F 414
Y DS+ F + + + + + +N L+ F++ L L LD + I + E+ F
Sbjct: 46 YCDSQGFHSVPNATDKGSLGLSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAF 105
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
L+ L L+ N++ LP + L +L LS+N ++ L PELF LR L+T +
Sbjct: 106 QGLYKLKELILSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLR 165
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
N L+ +P LF R+L + L N++ ++ N F G +R L L +N+L + +
Sbjct: 166 SNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHF 225
Query: 53 SPLNQLHKLQTLTLAWN 3
L+ LH TL L WN
Sbjct: 226 LRLSSLH---TLFLQWN 239
Score = 66.9 bits (156), Expect = 5e-11
Identities = 51/171 (29%), Positives = 81/171 (47%), Gaps = 1/171 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFI 411
N + + F+GL ++E+ +S+N L F+ L L+ L L + + L PE F
Sbjct: 95 NQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFY 154
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L+TL L N LR +P + L L LS N + LA FA L L ++
Sbjct: 155 GLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEH 214
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
N+L + + F L +L T+ L+ NKIS ++ ++ LDL+ N +
Sbjct: 215 NQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEI 265
Score = 62.1 bits (144), Expect = 1e-09
Identities = 44/169 (26%), Positives = 77/169 (45%), Gaps = 1/169 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FI 411
N L E+F GL +Q + + +N T+ +F + +L L L + +R L F
Sbjct: 143 NQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFA 202
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
LR L L NQL + + + L +L L +N ++ L + LE + G
Sbjct: 203 GLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTG 262
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
NE++ + ++F + NL + + NNK++ + S+ T+ LS N
Sbjct: 263 NEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSGN 311
>AB007876-1|BAA24846.2| 529|Homo sapiens KIAA0416 protein.
Length = 529
Score = 84.2 bits (199), Expect = 3e-16
Identities = 59/197 (29%), Positives = 97/197 (49%), Gaps = 6/197 (3%)
Frame = -3
Query: 575 YLDSEIFRGLDHIQE-----IKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-F 414
Y DS+ F + + + + + +N L+ F++ L L LD + I + E+ F
Sbjct: 59 YCDSQGFHSVPNATDKGSLGLSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAF 118
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
L+ L L+ N++ LP + L +L LS+N ++ L PELF LR L+T +
Sbjct: 119 QGLYKLKELILSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLR 178
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
N L+ +P LF R+L + L N++ ++ N F G +R L L +N+L + +
Sbjct: 179 SNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHF 238
Query: 53 SPLNQLHKLQTLTLAWN 3
L+ LH TL L WN
Sbjct: 239 LRLSSLH---TLFLQWN 252
Score = 66.9 bits (156), Expect = 5e-11
Identities = 51/171 (29%), Positives = 81/171 (47%), Gaps = 1/171 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFI 411
N + + F+GL ++E+ +S+N L F+ L L+ L L + + L PE F
Sbjct: 108 NQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFY 167
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L+TL L N LR +P + L L LS N + LA FA L L ++
Sbjct: 168 GLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEH 227
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
N+L + + F L +L T+ L+ NKIS ++ ++ LDL+ N +
Sbjct: 228 NQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEI 278
Score = 62.1 bits (144), Expect = 1e-09
Identities = 44/169 (26%), Positives = 77/169 (45%), Gaps = 1/169 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FI 411
N L E+F GL +Q + + +N T+ +F + +L L L + +R L F
Sbjct: 156 NQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFA 215
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
LR L L NQL + + + L +L L +N ++ L + LE + G
Sbjct: 216 GLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTG 275
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
NE++ + ++F + NL + + NNK++ + S+ T+ LS N
Sbjct: 276 NEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSGN 324
>BC117276-1|AAI17277.1| 420|Homo sapiens reticulon 4 receptor-like
2 protein.
Length = 420
Score = 83.8 bits (198), Expect = 4e-16
Identities = 58/174 (33%), Positives = 86/174 (49%), Gaps = 2/174 (1%)
Frame = -3
Query: 521 SNNVPLTLKEAVFSNLPALRTLQL-DLSSIREL-PEEFISNSPLRTLSLARNQLRALPRS 348
SNN+ T+ F +L AL L L D +R L P+ F L++L L R QL +LP +
Sbjct: 91 SNNLS-TIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGN 149
Query: 347 VLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVS 168
+ RG L L L N++ L +LFADL L + GN L++L + +F GL +L +
Sbjct: 150 IFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLL 209
Query: 167 LRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAW 6
L N++ + F+G + + L L N LA P + L L L+ W
Sbjct: 210 LHGNRLQGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNANPW 263
>BC113673-1|AAI13674.1| 420|Homo sapiens reticulon 4 receptor-like
2 protein.
Length = 420
Score = 83.8 bits (198), Expect = 4e-16
Identities = 58/174 (33%), Positives = 86/174 (49%), Gaps = 2/174 (1%)
Frame = -3
Query: 521 SNNVPLTLKEAVFSNLPALRTLQL-DLSSIREL-PEEFISNSPLRTLSLARNQLRALPRS 348
SNN+ T+ F +L AL L L D +R L P+ F L++L L R QL +LP +
Sbjct: 91 SNNLS-TIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGN 149
Query: 347 VLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVS 168
+ RG L L L N++ L +LFADL L + GN L++L + +F GL +L +
Sbjct: 150 IFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLL 209
Query: 167 LRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAW 6
L N++ + F+G + + L L N LA P + L L L+ W
Sbjct: 210 LHGNRLQGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNANPW 263
>AY250221-1|AAP82838.1| 420|Homo sapiens nogo receptor-like 3
protein.
Length = 420
Score = 83.8 bits (198), Expect = 4e-16
Identities = 58/174 (33%), Positives = 86/174 (49%), Gaps = 2/174 (1%)
Frame = -3
Query: 521 SNNVPLTLKEAVFSNLPALRTLQL-DLSSIREL-PEEFISNSPLRTLSLARNQLRALPRS 348
SNN+ T+ F +L AL L L D +R L P+ F L++L L R QL +LP +
Sbjct: 91 SNNLS-TIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGN 149
Query: 347 VLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVS 168
+ RG L L L N++ L +LFADL L + GN L++L + +F GL +L +
Sbjct: 150 IFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLL 209
Query: 167 LRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAW 6
L N++ + F+G + + L L N LA P + L L L+ W
Sbjct: 210 LHGNRLQGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNANPW 263
Score = 30.7 bits (66), Expect = 4.1
Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 2/78 (2%)
Frame = -3
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNR--LAFAP 66
+ N ++ L S F NL T+ L +N +S I TF+ ++ LDL NR + P
Sbjct: 67 LQNNLIRTLRPSTFGS--NLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHLRSLEP 124
Query: 65 DSLYSPLNQLHKLQTLTL 12
D+ L +LQ+L L
Sbjct: 125 DTFQG----LERLQSLHL 138
>AF532858-1|AAP21835.1| 420|Homo sapiens Nogo-66 receptor homolog-1
protein.
Length = 420
Score = 83.8 bits (198), Expect = 4e-16
Identities = 58/174 (33%), Positives = 86/174 (49%), Gaps = 2/174 (1%)
Frame = -3
Query: 521 SNNVPLTLKEAVFSNLPALRTLQL-DLSSIREL-PEEFISNSPLRTLSLARNQLRALPRS 348
SNN+ T+ F +L AL L L D +R L P+ F L++L L R QL +LP +
Sbjct: 91 SNNLS-TIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGN 149
Query: 347 VLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVS 168
+ RG L L L N++ L +LFADL L + GN L++L + +F GL +L +
Sbjct: 150 IFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLL 209
Query: 167 LRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAW 6
L N++ + F+G + + L L N LA P + L L L+ W
Sbjct: 210 LHGNRLQGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNANPW 263
>BC043165-1|AAH43165.1| 719|Homo sapiens leucine rich repeat and
fibronectin type III domain containing 5 protein.
Length = 719
Score = 81.0 bits (191), Expect = 3e-15
Identities = 44/121 (36%), Positives = 62/121 (51%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
L LA N + + R T L LTLS N ++ + P FADLR L ++ N L +
Sbjct: 56 LRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKIT 115
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHK 30
+ +FSGL NL + L NN++++IS F ++ LDLSYN L P + LH
Sbjct: 116 NDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHT 175
Query: 29 L 27
L
Sbjct: 176 L 176
Score = 54.0 bits (124), Expect = 4e-07
Identities = 38/154 (24%), Positives = 70/154 (45%), Gaps = 2/154 (1%)
Frame = -3
Query: 557 FRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSL 381
F + + ++ +S N + F++L LR L L+ + + ++ + S S L L L
Sbjct: 71 FANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLIL 130
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSL 201
NQL + + L L LSYN + + + + +L T +D N + +P
Sbjct: 131 NNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGT 190
Query: 200 FSGLRNLTTVSLRNNKISVISMN-TFQGATSIRT 102
FS L +T + + +NK+ + + FQ A + T
Sbjct: 191 FSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLAT 224
>AK055365-1|BAB70910.1| 719|Homo sapiens protein ( Homo sapiens
cDNA FLJ30803 fis, clone FEBRA2001245, weakly similar to
NAG14. ).
Length = 719
Score = 81.0 bits (191), Expect = 3e-15
Identities = 44/121 (36%), Positives = 62/121 (51%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
L LA N + + R T L LTLS N ++ + P FADLR L ++ N L +
Sbjct: 56 LRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKIT 115
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHK 30
+ +FSGL NL + L NN++++IS F ++ LDLSYN L P + LH
Sbjct: 116 NDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHT 175
Query: 29 L 27
L
Sbjct: 176 L 176
Score = 54.0 bits (124), Expect = 4e-07
Identities = 38/154 (24%), Positives = 70/154 (45%), Gaps = 2/154 (1%)
Frame = -3
Query: 557 FRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSL 381
F + + ++ +S N + F++L LR L L+ + + ++ + S S L L L
Sbjct: 71 FANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLIL 130
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSL 201
NQL + + L L LSYN + + + + +L T +D N + +P
Sbjct: 131 NNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGT 190
Query: 200 FSGLRNLTTVSLRNNKISVISMN-TFQGATSIRT 102
FS L +T + + +NK+ + + FQ A + T
Sbjct: 191 FSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLAT 224
>BC068590-1|AAH68590.1| 778|Homo sapiens LOC150356 protein protein.
Length = 778
Score = 80.6 bits (190), Expect = 4e-15
Identities = 56/178 (31%), Positives = 86/178 (48%), Gaps = 1/178 (0%)
Frame = -3
Query: 557 FRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSL 381
FRGL + + +++N L + L +LR L+L+ +++ EL P F + L TL+L
Sbjct: 122 FRGLGRLLLLNLASNHLRELPQEALDGLGSLRRLELEGNALEELRPGTFGALGALATLNL 181
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSL 201
A N L LP +G ++ L LS+NA++ LAPE A L AL + NELQ LP +
Sbjct: 182 AHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGPV 241
Query: 200 FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
S R L + L +N ++ +R L L L ++ +LH L
Sbjct: 242 LSQARGLARLELGHNPLTYAGEEDGLALPGLRELLLDGGALQALGPRAFAHCPRLHTL 299
Score = 67.7 bits (158), Expect = 3e-11
Identities = 46/174 (26%), Positives = 76/174 (43%), Gaps = 1/174 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N + + + F+G+ H+ + + + + E F L L L L + +RELP+E +
Sbjct: 88 NLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELPQEALD 147
Query: 407 N-SPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
LR L L N L L L +L L++NA+ L F L + +
Sbjct: 148 GLGSLRRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSH 207
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFA 69
N L VL +GL L +SL +N++ + A + L+L +N L +A
Sbjct: 208 NALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYA 261
Score = 66.9 bits (156), Expect = 5e-11
Identities = 51/171 (29%), Positives = 78/171 (45%), Gaps = 1/171 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N+ L F L + + +++N + L F L +R L+L +++ L E ++
Sbjct: 160 NALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALA 219
Query: 407 NSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
P LR LSL N+L+ALP VL L L L +N + E L L ++DG
Sbjct: 220 GLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAGEEDGLALPGLRELLLDG 279
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
LQ L F+ L T+ LR N++ ++ QG +R L L N L
Sbjct: 280 GALQALGPRAFAHCPRLHTLDLRGNQLD--TLPPLQGPGQLRRLRLQGNPL 328
Score = 63.3 bits (147), Expect = 6e-10
Identities = 49/187 (26%), Positives = 77/187 (41%), Gaps = 1/187 (0%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ RN F + F GL H+ + + + L+ + L L L L + + L
Sbjct: 448 LRRNHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLSAA 507
Query: 416 FISNSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+ +P L L L RN+ +P + LR L SL L NAV LAP RAL
Sbjct: 508 ALEGAPRLGYLYLERNRFLQVPGAALRALPSLFSLHLHDNAVDRLAPGDLGRTRALRWVY 567
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
+ GN + + R L + L N++ + +G ++ L LS N L D
Sbjct: 568 LSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDG 627
Query: 59 LYSPLNQ 39
+ P+ +
Sbjct: 628 AFQPVGR 634
Score = 59.3 bits (137), Expect = 1e-08
Identities = 44/144 (30%), Positives = 69/144 (47%), Gaps = 4/144 (2%)
Frame = -3
Query: 476 LPALRTLQLDLSS--IRELPEEFISNSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLS 306
+P L T +LDL ++ +P P L L L ++ + RG +L L L+
Sbjct: 76 IPEL-TQRLDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLA 134
Query: 305 YNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTF 126
N + EL E L +L ++GN L+ L F L L T++L +N + + F
Sbjct: 135 SNHLRELPQEALDGLGSLRRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAF 194
Query: 125 QGATSIRTLDLSYNRLA-FAPDSL 57
QG +R L LS+N L+ AP++L
Sbjct: 195 QGLLRVRWLRLSHNALSVLAPEAL 218
Score = 57.2 bits (132), Expect = 4e-08
Identities = 43/150 (28%), Positives = 65/150 (43%), Gaps = 1/150 (0%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ N+ YL + F+GL ++ +++S+N L + LPALR L L + ++ LP
Sbjct: 181 LAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGP 240
Query: 416 FISNS-PLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+S + L L L N L L L L A+ L P FA L T
Sbjct: 241 VLSQARGLARLELGHNPLTYAGEEDGLALPGLRELLLDGGALQALGPRAFAHCPRLHTLD 300
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKI 150
+ GN+L LP G L + L+ N +
Sbjct: 301 LRGNQLDTLPP--LQGPGQLRRLRLQGNPL 328
Score = 44.8 bits (101), Expect = 2e-04
Identities = 21/72 (29%), Positives = 40/72 (55%)
Frame = -3
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
+ GN L+V+P + F G+ +LT + LR+ ++ +++ F+G + L+L+ N L P
Sbjct: 85 LQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELPQE 144
Query: 59 LYSPLNQLHKLQ 24
L L +L+
Sbjct: 145 ALDGLGSLRRLE 156
Score = 43.2 bits (97), Expect = 7e-04
Identities = 37/141 (26%), Positives = 59/141 (41%), Gaps = 1/141 (0%)
Frame = -3
Query: 476 LPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNA 297
+P R + ++ +P F S++ L L L RN ++PR+ G L SL L +
Sbjct: 419 VPESRHSSCEGCGLQAVPRGFRSDTQL--LDLRRNHFPSVPRAAFPGLGHLVSLHLQHCG 476
Query: 296 VAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGA 117
+AEL A L L + N+L L + G L + L N+ + +
Sbjct: 477 IAELEAGALAGLGRLIYLYLSDNQLAGLSAAALEGAPRLGYLYLERNRFLQVPGAALRAL 536
Query: 116 TSIRTLDLSYNRL-AFAPDSL 57
S+ +L L N + AP L
Sbjct: 537 PSLFSLHLHDNAVDRLAPGDL 557
Score = 42.7 bits (96), Expect = 0.001
Identities = 33/100 (33%), Positives = 53/100 (53%), Gaps = 3/100 (3%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLP-ALRTLQLDLSSIREL-PEE 417
RN R + + GL + E+++S N L++ F + +L+ L L+ S + ++ P
Sbjct: 594 RNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQHLFLNSSGLEQICPGA 653
Query: 416 FISNSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYN 300
F P L++L L +NQLRALP L +QL + LS N
Sbjct: 654 FSGLGPGLQSLHLQKNQLRALP--ALPSLSQLELIDLSSN 691
>BC003193-1|AAH03193.1| 524|Homo sapiens leucine rich repeat
containing 1 protein.
Length = 524
Score = 80.6 bits (190), Expect = 4e-15
Identities = 60/181 (33%), Positives = 95/181 (52%), Gaps = 1/181 (0%)
Frame = -3
Query: 542 HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLR 363
H++ I + + + E ++ +L L LD + +RELPE+F LR L L+ N+++
Sbjct: 13 HVESIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQ 72
Query: 362 ALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRN 183
LP + QL L +S N + E+ PE + +AL+ GN L LP+S F L+N
Sbjct: 73 RLPPEIANFM-QLVELDVSRNEIPEI-PESISFCKALQVADFSGNPLTRLPES-FPELQN 129
Query: 182 LTTVSLRNNKISVISM-NTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAW 6
LT +S+ N IS+ S+ ++ +L+L N L + PDS L QL +L+ L L
Sbjct: 130 LTCLSV--NDISLQSLPENIGNLYNLASLELRENLLTYLPDS----LTQLRRLEELDLGN 183
Query: 5 N 3
N
Sbjct: 184 N 184
Score = 47.2 bits (107), Expect = 4e-05
Identities = 43/164 (26%), Positives = 78/164 (47%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L ++ +++ N+ L +++ + L L L L + I LPE + L+ L L NQ
Sbjct: 150 LYNLASLELRENLLTYLPDSL-TQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQ 208
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
L LP+ + L L +S N + L PE + L +L V+ N L+ +PD + L
Sbjct: 209 LSELPQEI-GNLKNLLCLDVSENRLERL-PEEISGLTSLTDLVISQNLLETIPDGI-GKL 265
Query: 188 RNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
+ L+ + + N+++ + S+ L L+ N+L P S+
Sbjct: 266 KKLSILKVDQNRLTQLP-EAVGECESLTELVLTENQLLTLPKSI 308
Score = 46.4 bits (105), Expect = 8e-05
Identities = 48/183 (26%), Positives = 84/183 (45%), Gaps = 4/183 (2%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N L EI GL + ++ IS N+ T+ + + L L L++D + + +LPE
Sbjct: 230 NRLERLPEEI-SGLTSLTDLVISQNLLETIPDGI-GKLKKLSILKVDQNRLTQLPEAVGE 287
Query: 407 NSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 228
L L L NQL LP+S+ + +L++L N + L P+ +L F + N
Sbjct: 288 CESLTELVLTENQLLTLPKSIGK-LKKLSNLNADRNKLVSL-PKEIGGCCSLTVFCVRDN 345
Query: 227 ELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNR----LAFAPDS 60
L +P + S L + + N++ + ++ A ++ L LS N+ L F D+
Sbjct: 346 RLTRIPAEV-SQATELHVLDVAGNRLLHLPLSL--TALKLKALWLSDNQSQPLLTFQTDT 402
Query: 59 LYS 51
Y+
Sbjct: 403 DYT 405
Score = 35.1 bits (77), Expect = 0.19
Identities = 23/95 (24%), Positives = 46/95 (48%)
Frame = -3
Query: 341 RGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLR 162
R + S+ + ++ + E++ R+LE ++D N+L+ LP+ F L L + L
Sbjct: 9 RCNRHVESIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQ-LVKLRKLGLS 67
Query: 161 NNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
+N+I + + LD+S N + P+S+
Sbjct: 68 DNEIQRLPPE-IANFMQLVELDVSRNEIPEIPESI 101
>AL513211-1|CAI17358.1| 524|Homo sapiens leucine rich repeat
containing 1 protein.
Length = 524
Score = 80.6 bits (190), Expect = 4e-15
Identities = 60/181 (33%), Positives = 95/181 (52%), Gaps = 1/181 (0%)
Frame = -3
Query: 542 HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLR 363
H++ I + + + E ++ +L L LD + +RELPE+F LR L L+ N+++
Sbjct: 13 HVESIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQ 72
Query: 362 ALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRN 183
LP + QL L +S N + E+ PE + +AL+ GN L LP+S F L+N
Sbjct: 73 RLPPEIANFM-QLVELDVSRNEIPEI-PESISFCKALQVADFSGNPLTRLPES-FPELQN 129
Query: 182 LTTVSLRNNKISVISM-NTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAW 6
LT +S+ N IS+ S+ ++ +L+L N L + PDS L QL +L+ L L
Sbjct: 130 LTCLSV--NDISLQSLPENIGNLYNLASLELRENLLTYLPDS----LTQLRRLEELDLGN 183
Query: 5 N 3
N
Sbjct: 184 N 184
Score = 47.2 bits (107), Expect = 4e-05
Identities = 43/164 (26%), Positives = 78/164 (47%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L ++ +++ N+ L +++ + L L L L + I LPE + L+ L L NQ
Sbjct: 150 LYNLASLELRENLLTYLPDSL-TQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQ 208
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
L LP+ + L L +S N + L PE + L +L V+ N L+ +PD + L
Sbjct: 209 LSELPQEI-GNLKNLLCLDVSENRLERL-PEEISGLTSLTDLVISQNLLETIPDGI-GKL 265
Query: 188 RNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
+ L+ + + N+++ + S+ L L+ N+L P S+
Sbjct: 266 KKLSILKVDQNRLTQLP-EAVGECESLTELVLTENQLLTLPKSI 308
Score = 46.4 bits (105), Expect = 8e-05
Identities = 48/183 (26%), Positives = 84/183 (45%), Gaps = 4/183 (2%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N L EI GL + ++ IS N+ T+ + + L L L++D + + +LPE
Sbjct: 230 NRLERLPEEI-SGLTSLTDLVISQNLLETIPDGI-GKLKKLSILKVDQNRLTQLPEAVGE 287
Query: 407 NSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 228
L L L NQL LP+S+ + +L++L N + L P+ +L F + N
Sbjct: 288 CESLTELVLTENQLLTLPKSIGK-LKKLSNLNADRNKLVSL-PKEIGGCCSLTVFCVRDN 345
Query: 227 ELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNR----LAFAPDS 60
L +P + S L + + N++ + ++ A ++ L LS N+ L F D+
Sbjct: 346 RLTRIPAEV-SQATELHVLDVAGNRLLHLPLSL--TALKLKALWLSDNQSQPLLTFQTDT 402
Query: 59 LYS 51
Y+
Sbjct: 403 DYT 405
Score = 35.1 bits (77), Expect = 0.19
Identities = 23/95 (24%), Positives = 46/95 (48%)
Frame = -3
Query: 341 RGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLR 162
R + S+ + ++ + E++ R+LE ++D N+L+ LP+ F L L + L
Sbjct: 9 RCNRHVESIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQ-LVKLRKLGLS 67
Query: 161 NNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
+N+I + + LD+S N + P+S+
Sbjct: 68 DNEIQRLPPE-IANFMQLVELDVSRNEIPEIPESI 101
>AL035681-1|CAI22653.1| 762|Homo sapiens protein ( Human DNA
sequence from clone RP4-756G23 on chromosome
22q13.31-13.33. ).
Length = 762
Score = 80.6 bits (190), Expect = 4e-15
Identities = 56/178 (31%), Positives = 86/178 (48%), Gaps = 1/178 (0%)
Frame = -3
Query: 557 FRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSL 381
FRGL + + +++N L + L +LR L+L+ +++ EL P F + L TL+L
Sbjct: 106 FRGLGRLLLLNLASNHLRELPQEALDGLGSLRRLELEGNALEELRPGTFGALGALATLNL 165
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSL 201
A N L LP +G ++ L LS+NA++ LAPE A L AL + NELQ LP +
Sbjct: 166 AHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGPV 225
Query: 200 FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
S R L + L +N ++ +R L L L ++ +LH L
Sbjct: 226 LSQARGLARLELGHNPLTYAGEEDGLALPGLRELLLDGGALQALGPRAFAHCPRLHTL 283
Score = 67.7 bits (158), Expect = 3e-11
Identities = 46/174 (26%), Positives = 76/174 (43%), Gaps = 1/174 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N + + + F+G+ H+ + + + + E F L L L L + +RELP+E +
Sbjct: 72 NLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELPQEALD 131
Query: 407 N-SPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
LR L L N L L L +L L++NA+ L F L + +
Sbjct: 132 GLGSLRRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSH 191
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFA 69
N L VL +GL L +SL +N++ + A + L+L +N L +A
Sbjct: 192 NALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYA 245
Score = 66.9 bits (156), Expect = 5e-11
Identities = 51/171 (29%), Positives = 78/171 (45%), Gaps = 1/171 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N+ L F L + + +++N + L F L +R L+L +++ L E ++
Sbjct: 144 NALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALA 203
Query: 407 NSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
P LR LSL N+L+ALP VL L L L +N + E L L ++DG
Sbjct: 204 GLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAGEEDGLALPGLRELLLDG 263
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
LQ L F+ L T+ LR N++ ++ QG +R L L N L
Sbjct: 264 GALQALGPRAFAHCPRLHTLDLRGNQLD--TLPPLQGPGQLRRLRLQGNPL 312
Score = 63.7 bits (148), Expect = 5e-10
Identities = 49/187 (26%), Positives = 77/187 (41%), Gaps = 1/187 (0%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ RN F + F GL H+ + + + L+ + L L L L + + L
Sbjct: 432 LRRNHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLSAA 491
Query: 416 FISNSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+ +P L L L RN+ +P + LR L SL L NAV LAP RAL
Sbjct: 492 ALEGAPRLGYLYLERNRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRWVY 551
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
+ GN + + R L + L N++ + +G ++ L LS N L D
Sbjct: 552 LSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDG 611
Query: 59 LYSPLNQ 39
+ P+ +
Sbjct: 612 AFQPVGR 618
Score = 59.3 bits (137), Expect = 1e-08
Identities = 44/144 (30%), Positives = 69/144 (47%), Gaps = 4/144 (2%)
Frame = -3
Query: 476 LPALRTLQLDLSS--IRELPEEFISNSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLS 306
+P L T +LDL ++ +P P L L L ++ + RG +L L L+
Sbjct: 60 IPEL-TQRLDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLA 118
Query: 305 YNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTF 126
N + EL E L +L ++GN L+ L F L L T++L +N + + F
Sbjct: 119 SNHLRELPQEALDGLGSLRRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAF 178
Query: 125 QGATSIRTLDLSYNRLA-FAPDSL 57
QG +R L LS+N L+ AP++L
Sbjct: 179 QGLLRVRWLRLSHNALSVLAPEAL 202
Score = 57.2 bits (132), Expect = 4e-08
Identities = 43/150 (28%), Positives = 65/150 (43%), Gaps = 1/150 (0%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ N+ YL + F+GL ++ +++S+N L + LPALR L L + ++ LP
Sbjct: 165 LAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGP 224
Query: 416 FISNS-PLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+S + L L L N L L L L A+ L P FA L T
Sbjct: 225 VLSQARGLARLELGHNPLTYAGEEDGLALPGLRELLLDGGALQALGPRAFAHCPRLHTLD 284
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKI 150
+ GN+L LP G L + L+ N +
Sbjct: 285 LRGNQLDTLPP--LQGPGQLRRLRLQGNPL 312
Score = 44.8 bits (101), Expect = 2e-04
Identities = 21/72 (29%), Positives = 40/72 (55%)
Frame = -3
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
+ GN L+V+P + F G+ +LT + LR+ ++ +++ F+G + L+L+ N L P
Sbjct: 69 LQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELPQE 128
Query: 59 LYSPLNQLHKLQ 24
L L +L+
Sbjct: 129 ALDGLGSLRRLE 140
Score = 43.6 bits (98), Expect = 5e-04
Identities = 37/141 (26%), Positives = 59/141 (41%), Gaps = 1/141 (0%)
Frame = -3
Query: 476 LPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNA 297
+P R + ++ +P F S++ L L L RN ++PR+ G L SL L +
Sbjct: 403 VPESRHSSCEGCGLQAVPRGFPSDTQL--LDLRRNHFPSVPRAAFPGLGHLVSLHLQHCG 460
Query: 296 VAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGA 117
+AEL A L L + N+L L + G L + L N+ + +
Sbjct: 461 IAELEAGALAGLGRLIYLYLSDNQLAGLSAAALEGAPRLGYLYLERNRFLQVPGAALRAL 520
Query: 116 TSIRTLDLSYNRL-AFAPDSL 57
S+ +L L N + AP L
Sbjct: 521 PSLFSLHLQDNAVDRLAPGDL 541
Score = 42.7 bits (96), Expect = 0.001
Identities = 33/100 (33%), Positives = 53/100 (53%), Gaps = 3/100 (3%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLP-ALRTLQLDLSSIREL-PEE 417
RN R + + GL + E+++S N L++ F + +L+ L L+ S + ++ P
Sbjct: 578 RNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQHLFLNSSGLEQICPGA 637
Query: 416 FISNSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYN 300
F P L++L L +NQLRALP L +QL + LS N
Sbjct: 638 FSGLGPGLQSLHLQKNQLRALP--ALPSLSQLELIDLSSN 675
>AL033384-1|CAI21666.1| 524|Homo sapiens leucine rich repeat
containing 1 protein.
Length = 524
Score = 80.6 bits (190), Expect = 4e-15
Identities = 60/181 (33%), Positives = 95/181 (52%), Gaps = 1/181 (0%)
Frame = -3
Query: 542 HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLR 363
H++ I + + + E ++ +L L LD + +RELPE+F LR L L+ N+++
Sbjct: 13 HVESIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQ 72
Query: 362 ALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRN 183
LP + QL L +S N + E+ PE + +AL+ GN L LP+S F L+N
Sbjct: 73 RLPPEIANFM-QLVELDVSRNEIPEI-PESISFCKALQVADFSGNPLTRLPES-FPELQN 129
Query: 182 LTTVSLRNNKISVISM-NTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAW 6
LT +S+ N IS+ S+ ++ +L+L N L + PDS L QL +L+ L L
Sbjct: 130 LTCLSV--NDISLQSLPENIGNLYNLASLELRENLLTYLPDS----LTQLRRLEELDLGN 183
Query: 5 N 3
N
Sbjct: 184 N 184
Score = 47.2 bits (107), Expect = 4e-05
Identities = 43/164 (26%), Positives = 78/164 (47%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L ++ +++ N+ L +++ + L L L L + I LPE + L+ L L NQ
Sbjct: 150 LYNLASLELRENLLTYLPDSL-TQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQ 208
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
L LP+ + L L +S N + L PE + L +L V+ N L+ +PD + L
Sbjct: 209 LSELPQEI-GNLKNLLCLDVSENRLERL-PEEISGLTSLTDLVISQNLLETIPDGI-GKL 265
Query: 188 RNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
+ L+ + + N+++ + S+ L L+ N+L P S+
Sbjct: 266 KKLSILKVDQNRLTQLP-EAVGECESLTELVLTENQLLTLPKSI 308
Score = 46.4 bits (105), Expect = 8e-05
Identities = 48/183 (26%), Positives = 84/183 (45%), Gaps = 4/183 (2%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N L EI GL + ++ IS N+ T+ + + L L L++D + + +LPE
Sbjct: 230 NRLERLPEEI-SGLTSLTDLVISQNLLETIPDGI-GKLKKLSILKVDQNRLTQLPEAVGE 287
Query: 407 NSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 228
L L L NQL LP+S+ + +L++L N + L P+ +L F + N
Sbjct: 288 CESLTELVLTENQLLTLPKSIGK-LKKLSNLNADRNKLVSL-PKEIGGCCSLTVFCVRDN 345
Query: 227 ELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNR----LAFAPDS 60
L +P + S L + + N++ + ++ A ++ L LS N+ L F D+
Sbjct: 346 RLTRIPAEV-SQATELHVLDVAGNRLLHLPLSL--TALKLKALWLSDNQSQPLLTFQTDT 402
Query: 59 LYS 51
Y+
Sbjct: 403 DYT 405
Score = 35.1 bits (77), Expect = 0.19
Identities = 23/95 (24%), Positives = 46/95 (48%)
Frame = -3
Query: 341 RGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLR 162
R + S+ + ++ + E++ R+LE ++D N+L+ LP+ F L L + L
Sbjct: 9 RCNRHVESIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQ-LVKLRKLGLS 67
Query: 161 NNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
+N+I + + LD+S N + P+S+
Sbjct: 68 DNEIQRLPPE-IANFMQLVELDVSRNEIPEIPESI 101
>AK021896-1|BAB13929.1| 197|Homo sapiens protein ( Homo sapiens
cDNA FLJ11834 fis, clone HEMBA1006583, weakly similar to
Drosophila melanogaster Scribble (scrib) mRNA. ).
Length = 197
Score = 80.6 bits (190), Expect = 4e-15
Identities = 60/181 (33%), Positives = 95/181 (52%), Gaps = 1/181 (0%)
Frame = -3
Query: 542 HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLR 363
H++ I + + + E ++ +L L LD + +RELPE+F LR L L+ N+++
Sbjct: 13 HVESIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQ 72
Query: 362 ALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRN 183
LP + QL L +S N + E+ PE + +AL+ GN L LP+S F L+N
Sbjct: 73 RLPPEIANFM-QLVELDVSRNEIPEI-PESISFCKALQVADFSGNPLTRLPES-FPELQN 129
Query: 182 LTTVSLRNNKISVISM-NTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAW 6
LT +S+ N IS+ S+ ++ +L+L N L + PDS L QL +L+ L L
Sbjct: 130 LTCLSV--NDISLQSLPENIGNLYNLASLELRENLLTYLPDS----LTQLRRLEELDLGN 183
Query: 5 N 3
N
Sbjct: 184 N 184
Score = 35.1 bits (77), Expect = 0.19
Identities = 23/95 (24%), Positives = 46/95 (48%)
Frame = -3
Query: 341 RGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLR 162
R + S+ + ++ + E++ R+LE ++D N+L+ LP+ F L L + L
Sbjct: 9 RCNRHVESIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQ-LVKLRKLGLS 67
Query: 161 NNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
+N+I + + LD+S N + P+S+
Sbjct: 68 DNEIQRLPPE-IANFMQLVELDVSRNEIPEIPESI 101
>AF359380-1|AAK72246.1| 524|Homo sapiens LANO adaptor protein
protein.
Length = 524
Score = 80.6 bits (190), Expect = 4e-15
Identities = 60/181 (33%), Positives = 95/181 (52%), Gaps = 1/181 (0%)
Frame = -3
Query: 542 HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLR 363
H++ I + + + E ++ +L L LD + +RELPE+F LR L L+ N+++
Sbjct: 13 HVESIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQ 72
Query: 362 ALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRN 183
LP + QL L +S N + E+ PE + +AL+ GN L LP+S F L+N
Sbjct: 73 RLPPEIANFM-QLVELDVSRNEIPEI-PESISFCKALQVADFSGNPLTRLPES-FPELQN 129
Query: 182 LTTVSLRNNKISVISM-NTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAW 6
LT +S+ N IS+ S+ ++ +L+L N L + PDS L QL +L+ L L
Sbjct: 130 LTCLSV--NDISLQSLPENIGNLYNLASLELRENLLTYLPDS----LTQLRRLEELDLGN 183
Query: 5 N 3
N
Sbjct: 184 N 184
Score = 47.2 bits (107), Expect = 4e-05
Identities = 43/164 (26%), Positives = 78/164 (47%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L ++ +++ N+ L +++ + L L L L + I LPE + L+ L L NQ
Sbjct: 150 LYNLASLELRENLLTYLPDSL-TQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQ 208
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
L LP+ + L L +S N + L PE + L +L V+ N L+ +PD + L
Sbjct: 209 LSELPQEI-GNLKNLLCLDVSENRLERL-PEEISGLTSLTDLVISQNLLETIPDGI-GKL 265
Query: 188 RNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
+ L+ + + N+++ + S+ L L+ N+L P S+
Sbjct: 266 KKLSILKVDQNRLTQLP-EAVGECESLTELVLTENQLLTLPKSI 308
Score = 46.4 bits (105), Expect = 8e-05
Identities = 48/183 (26%), Positives = 84/183 (45%), Gaps = 4/183 (2%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N L EI GL + ++ IS N+ T+ + + L L L++D + + +LPE
Sbjct: 230 NRLERLPEEI-SGLTSLTDLVISQNLLETIPDGI-GKLKKLSILKVDQNRLTQLPEAVGE 287
Query: 407 NSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 228
L L L NQL LP+S+ + +L++L N + L P+ +L F + N
Sbjct: 288 CESLTELVLTENQLLTLPKSIGK-LKKLSNLNADRNKLVSL-PKEIGGCCSLTVFCVRDN 345
Query: 227 ELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNR----LAFAPDS 60
L +P + S L + + N++ + ++ A ++ L LS N+ L F D+
Sbjct: 346 RLTRIPAEV-SQATELHVLDVAGNRLLHLPLSL--TALKLKALWLSDNQSQPLLTFQTDT 402
Query: 59 LYS 51
Y+
Sbjct: 403 DYT 405
Score = 35.1 bits (77), Expect = 0.19
Identities = 23/95 (24%), Positives = 46/95 (48%)
Frame = -3
Query: 341 RGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLR 162
R + S+ + ++ + E++ R+LE ++D N+L+ LP+ F L L + L
Sbjct: 9 RCNRHVESIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQ-LVKLRKLGLS 67
Query: 161 NNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
+N+I + + LD+S N + P+S+
Sbjct: 68 DNEIQRLPPE-IANFMQLVELDVSRNEIPEIPESI 101
>AF332199-1|AAK69623.1| 524|Homo sapiens leucine-rich repeats
protein protein.
Length = 524
Score = 80.6 bits (190), Expect = 4e-15
Identities = 60/181 (33%), Positives = 95/181 (52%), Gaps = 1/181 (0%)
Frame = -3
Query: 542 HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLR 363
H++ I + + + E ++ +L L LD + +RELPE+F LR L L+ N+++
Sbjct: 13 HVESIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQ 72
Query: 362 ALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRN 183
LP + QL L +S N + E+ PE + +AL+ GN L LP+S F L+N
Sbjct: 73 RLPPEIANFM-QLVELDVSRNEIPEI-PESISFCKALQVADFSGNPLTRLPES-FPELQN 129
Query: 182 LTTVSLRNNKISVISM-NTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAW 6
LT +S+ N IS+ S+ ++ +L+L N L + PDS L QL +L+ L L
Sbjct: 130 LTCLSV--NDISLQSLPENIGNLYNLASLELRENLLTYLPDS----LTQLRRLEELDLGN 183
Query: 5 N 3
N
Sbjct: 184 N 184
Score = 47.2 bits (107), Expect = 4e-05
Identities = 43/164 (26%), Positives = 78/164 (47%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L ++ +++ N+ L +++ + L L L L + I LPE + L+ L L NQ
Sbjct: 150 LYNLASLELRENLLTYLPDSL-TQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQ 208
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
L LP+ + L L +S N + L PE + L +L V+ N L+ +PD + L
Sbjct: 209 LSELPQEI-GNLKNLLCLDVSENRLERL-PEEISGLTSLTDLVISQNLLETIPDGI-GKL 265
Query: 188 RNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
+ L+ + + N+++ + S+ L L+ N+L P S+
Sbjct: 266 KKLSILKVDQNRLTQLP-EAVGECESLTELVLTENQLLTLPKSI 308
Score = 46.4 bits (105), Expect = 8e-05
Identities = 48/183 (26%), Positives = 84/183 (45%), Gaps = 4/183 (2%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N L EI GL + ++ IS N+ T+ + + L L L++D + + +LPE
Sbjct: 230 NRLERLPEEI-SGLTSLTDLVISQNLLETIPDGI-GKLKKLSILKVDQNRLTQLPEAVGE 287
Query: 407 NSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 228
L L L NQL LP+S+ + +L++L N + L P+ +L F + N
Sbjct: 288 CESLTELVLTENQLLTLPKSIGK-LKKLSNLNADRNKLVSL-PKEIGGCCSLTVFCVRDN 345
Query: 227 ELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNR----LAFAPDS 60
L +P + S L + + N++ + ++ A ++ L LS N+ L F D+
Sbjct: 346 RLTRIPAEV-SQATELHVLDVAGNRLLHLPLSL--TALKLKALWLSDNQSQPLLTFQTDT 402
Query: 59 LYS 51
Y+
Sbjct: 403 DYT 405
Score = 35.1 bits (77), Expect = 0.19
Identities = 23/95 (24%), Positives = 46/95 (48%)
Frame = -3
Query: 341 RGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLR 162
R + S+ + ++ + E++ R+LE ++D N+L+ LP+ F L L + L
Sbjct: 9 RCNRHVESIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQ-LVKLRKLGLS 67
Query: 161 NNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
+N+I + + LD+S N + P+S+
Sbjct: 68 DNEIQRLPPE-IANFMQLVELDVSRNEIPEIPESI 101
>U88879-1|AAC34134.1| 904|Homo sapiens Toll-like receptor 3
protein.
Length = 904
Score = 79.8 bits (188), Expect = 7e-15
Identities = 51/145 (35%), Positives = 77/145 (53%)
Frame = -3
Query: 437 IRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 258
+ ++P++ +N + L+L NQLR LP + +QLTSL + +N +++L PEL L
Sbjct: 42 LTQVPDDLPTN--ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLP 99
Query: 257 ALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
L+ + NEL L D F+ NLT + L +N I I N F ++ TLDLS+N L
Sbjct: 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
Query: 77 AFAPDSLYSPLNQLHKLQTLTLAWN 3
+ + QL LQ L L+ N
Sbjct: 160 S---STKLGTQVQLENLQELLLSNN 181
Score = 59.3 bits (137), Expect = 1e-08
Identities = 52/182 (28%), Positives = 85/182 (46%), Gaps = 8/182 (4%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPL--TLKEAVFSNLP--ALRTLQLDLSSIRE 429
M N + S +F GL +++ + +SN+ TL F +L L L L + I +
Sbjct: 362 MEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISK 421
Query: 428 LPEEFIS-NSPLRTLSLARNQL-RALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRA 255
+ + S L L L N++ + L RG + + LSYN +L FA + +
Sbjct: 422 IESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPS 481
Query: 254 LETFVMDGNELQVLPDSL--FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNR 81
L+ ++ L+ + S F LRNLT + L NN I+ I+ + +G + LDL +N
Sbjct: 482 LQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNN 541
Query: 80 LA 75
LA
Sbjct: 542 LA 543
Score = 52.8 bits (121), Expect = 9e-07
Identities = 55/197 (27%), Positives = 89/197 (45%), Gaps = 10/197 (5%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLD---LSSIREL 426
+ N L + F ++ E+ + +N +K F L TL L LSS +
Sbjct: 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLR--GQTQLTSLTLSYNAVAELAPELFADLRAL 252
+ + N L+ L L+ N+++AL L + L L LS N + E +P F + L
Sbjct: 166 TQVQLEN--LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRL 223
Query: 251 ETFVMDGNEL-QVLPDSLFSGLRN--LTTVSLRNNKISVISMNTFQGA--TSIRTLDLSY 87
++ +L L + L L N + +SL N+++S S TF G T++ LDLSY
Sbjct: 224 FGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
Query: 86 NRLAFAPDSLYSPLNQL 36
N L + ++ L QL
Sbjct: 284 NNLNVVGNDSFAWLPQL 300
Score = 49.2 bits (112), Expect = 1e-05
Identities = 43/165 (26%), Positives = 74/165 (44%), Gaps = 10/165 (6%)
Frame = -3
Query: 485 FSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRAL--------PRSVLRGQ 333
F L L L L ++I + ++ + L L L N L L P L+G
Sbjct: 502 FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGL 561
Query: 332 TQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNK 153
+ L L L N E+ E+F DL L+ + N L LP S+F+ +L +++L+ N
Sbjct: 562 SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNL 621
Query: 152 ISVISMNTFQGA-TSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQT 21
I+ + F A ++ LD+ +N +S+ +N +++ T
Sbjct: 622 ITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHT 666
Score = 44.4 bits (100), Expect = 3e-04
Identities = 41/181 (22%), Positives = 80/181 (44%), Gaps = 8/181 (4%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+M NS + + + F ++ + +S+N + K L L+ L L + I+ L E
Sbjct: 130 LMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSE 189
Query: 416 ---FISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVA-ELAPELFADLR--A 255
+NS L+ L L+ NQ++ +L L L+ + L +L +L +
Sbjct: 190 ELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTS 249
Query: 254 LETFVMDGNELQVLPDSLFSGLR--NLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNR 81
+ + ++L ++ F GL+ NLT + L N ++V+ ++F + L YN
Sbjct: 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
Query: 80 L 78
+
Sbjct: 310 I 310
>DQ445682-1|ABE01399.1| 904|Homo sapiens Toll-like receptor 3
isoform NT2-N protein.
Length = 904
Score = 79.8 bits (188), Expect = 7e-15
Identities = 51/145 (35%), Positives = 77/145 (53%)
Frame = -3
Query: 437 IRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 258
+ ++P++ +N + L+L NQLR LP + +QLTSL + +N +++L PEL L
Sbjct: 42 LTQVPDDLPTN--ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLP 99
Query: 257 ALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
L+ + NEL L D F+ NLT + L +N I I N F ++ TLDLS+N L
Sbjct: 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
Query: 77 AFAPDSLYSPLNQLHKLQTLTLAWN 3
+ + QL LQ L L+ N
Sbjct: 160 S---STKLGTQVQLENLQELLLSNN 181
Score = 59.3 bits (137), Expect = 1e-08
Identities = 52/182 (28%), Positives = 85/182 (46%), Gaps = 8/182 (4%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPL--TLKEAVFSNLP--ALRTLQLDLSSIRE 429
M N + S +F GL +++ + +SN+ TL F +L L L L + I +
Sbjct: 362 MEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISK 421
Query: 428 LPEEFIS-NSPLRTLSLARNQL-RALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRA 255
+ + S L L L N++ + L RG + + LSYN +L FA + +
Sbjct: 422 IESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPS 481
Query: 254 LETFVMDGNELQVLPDSL--FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNR 81
L+ ++ L+ + S F LRNLT + L NN I+ I+ + +G + LDL +N
Sbjct: 482 LQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNN 541
Query: 80 LA 75
LA
Sbjct: 542 LA 543
Score = 52.8 bits (121), Expect = 9e-07
Identities = 55/197 (27%), Positives = 89/197 (45%), Gaps = 10/197 (5%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLD---LSSIREL 426
+ N L + F ++ E+ + +N +K F L TL L LSS +
Sbjct: 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLR--GQTQLTSLTLSYNAVAELAPELFADLRAL 252
+ + N L+ L L+ N+++AL L + L L LS N + E +P F + L
Sbjct: 166 TQVQLEN--LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRL 223
Query: 251 ETFVMDGNEL-QVLPDSLFSGLRN--LTTVSLRNNKISVISMNTFQGA--TSIRTLDLSY 87
++ +L L + L L N + +SL N+++S S TF G T++ LDLSY
Sbjct: 224 FGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
Query: 86 NRLAFAPDSLYSPLNQL 36
N L + ++ L QL
Sbjct: 284 NNLNVVGNDSFAWLPQL 300
Score = 49.2 bits (112), Expect = 1e-05
Identities = 43/165 (26%), Positives = 74/165 (44%), Gaps = 10/165 (6%)
Frame = -3
Query: 485 FSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRAL--------PRSVLRGQ 333
F L L L L ++I + ++ + L L L N L L P L+G
Sbjct: 502 FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGL 561
Query: 332 TQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNK 153
+ L L L N E+ E+F DL L+ + N L LP S+F+ +L +++L+ N
Sbjct: 562 SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNL 621
Query: 152 ISVISMNTFQGA-TSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQT 21
I+ + F A ++ LD+ +N +S+ +N +++ T
Sbjct: 622 ITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHT 666
Score = 44.4 bits (100), Expect = 3e-04
Identities = 41/181 (22%), Positives = 80/181 (44%), Gaps = 8/181 (4%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+M NS + + + F ++ + +S+N + K L L+ L L + I+ L E
Sbjct: 130 LMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSE 189
Query: 416 ---FISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVA-ELAPELFADLR--A 255
+NS L+ L L+ NQ++ +L L L+ + L +L +L +
Sbjct: 190 ELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTS 249
Query: 254 LETFVMDGNELQVLPDSLFSGLR--NLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNR 81
+ + ++L ++ F GL+ NLT + L N ++V+ ++F + L YN
Sbjct: 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
Query: 80 L 78
+
Sbjct: 310 I 310
>BC096335-1|AAH96335.1| 904|Homo sapiens toll-like receptor 3
protein.
Length = 904
Score = 79.8 bits (188), Expect = 7e-15
Identities = 51/145 (35%), Positives = 77/145 (53%)
Frame = -3
Query: 437 IRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 258
+ ++P++ +N + L+L NQLR LP + +QLTSL + +N +++L PEL L
Sbjct: 42 LTQVPDDLPTN--ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLP 99
Query: 257 ALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
L+ + NEL L D F+ NLT + L +N I I N F ++ TLDLS+N L
Sbjct: 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
Query: 77 AFAPDSLYSPLNQLHKLQTLTLAWN 3
+ + QL LQ L L+ N
Sbjct: 160 S---STKLGTQVQLENLQELLLSNN 181
Score = 59.3 bits (137), Expect = 1e-08
Identities = 52/182 (28%), Positives = 85/182 (46%), Gaps = 8/182 (4%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPL--TLKEAVFSNLP--ALRTLQLDLSSIRE 429
M N + S +F GL +++ + +SN+ TL F +L L L L + I +
Sbjct: 362 MEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISK 421
Query: 428 LPEEFIS-NSPLRTLSLARNQL-RALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRA 255
+ + S L L L N++ + L RG + + LSYN +L FA + +
Sbjct: 422 IESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPS 481
Query: 254 LETFVMDGNELQVLPDSL--FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNR 81
L+ ++ L+ + S F LRNLT + L NN I+ I+ + +G + LDL +N
Sbjct: 482 LQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNN 541
Query: 80 LA 75
LA
Sbjct: 542 LA 543
Score = 52.8 bits (121), Expect = 9e-07
Identities = 55/197 (27%), Positives = 89/197 (45%), Gaps = 10/197 (5%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLD---LSSIREL 426
+ N L + F ++ E+ + +N +K F L TL L LSS +
Sbjct: 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLR--GQTQLTSLTLSYNAVAELAPELFADLRAL 252
+ + N L+ L L+ N+++AL L + L L LS N + E +P F + L
Sbjct: 166 TQVQLEN--LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRL 223
Query: 251 ETFVMDGNEL-QVLPDSLFSGLRN--LTTVSLRNNKISVISMNTFQGA--TSIRTLDLSY 87
++ +L L + L L N + +SL N+++S S TF G T++ LDLSY
Sbjct: 224 FGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
Query: 86 NRLAFAPDSLYSPLNQL 36
N L + ++ L QL
Sbjct: 284 NNLNVVGNDSFAWLPQL 300
Score = 49.2 bits (112), Expect = 1e-05
Identities = 43/165 (26%), Positives = 74/165 (44%), Gaps = 10/165 (6%)
Frame = -3
Query: 485 FSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRAL--------PRSVLRGQ 333
F L L L L ++I + ++ + L L L N L L P L+G
Sbjct: 502 FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGL 561
Query: 332 TQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNK 153
+ L L L N E+ E+F DL L+ + N L LP S+F+ +L +++L+ N
Sbjct: 562 SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNL 621
Query: 152 ISVISMNTFQGA-TSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQT 21
I+ + F A ++ LD+ +N +S+ +N +++ T
Sbjct: 622 ITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHT 666
Score = 44.4 bits (100), Expect = 3e-04
Identities = 41/181 (22%), Positives = 80/181 (44%), Gaps = 8/181 (4%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+M NS + + + F ++ + +S+N + K L L+ L L + I+ L E
Sbjct: 130 LMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSE 189
Query: 416 ---FISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVA-ELAPELFADLR--A 255
+NS L+ L L+ NQ++ +L L L+ + L +L +L +
Sbjct: 190 ELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTS 249
Query: 254 LETFVMDGNELQVLPDSLFSGLR--NLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNR 81
+ + ++L ++ F GL+ NLT + L N ++V+ ++F + L YN
Sbjct: 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
Query: 80 L 78
+
Sbjct: 310 I 310
>BC096334-1|AAH96334.1| 904|Homo sapiens toll-like receptor 3
protein.
Length = 904
Score = 79.8 bits (188), Expect = 7e-15
Identities = 51/145 (35%), Positives = 77/145 (53%)
Frame = -3
Query: 437 IRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 258
+ ++P++ +N + L+L NQLR LP + +QLTSL + +N +++L PEL L
Sbjct: 42 LTQVPDDLPTN--ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLP 99
Query: 257 ALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
L+ + NEL L D F+ NLT + L +N I I N F ++ TLDLS+N L
Sbjct: 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
Query: 77 AFAPDSLYSPLNQLHKLQTLTLAWN 3
+ + QL LQ L L+ N
Sbjct: 160 S---STKLGTQVQLENLQELLLSNN 181
Score = 59.3 bits (137), Expect = 1e-08
Identities = 52/182 (28%), Positives = 85/182 (46%), Gaps = 8/182 (4%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPL--TLKEAVFSNLP--ALRTLQLDLSSIRE 429
M N + S +F GL +++ + +SN+ TL F +L L L L + I +
Sbjct: 362 MEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISK 421
Query: 428 LPEEFIS-NSPLRTLSLARNQL-RALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRA 255
+ + S L L L N++ + L RG + + LSYN +L FA + +
Sbjct: 422 IESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPS 481
Query: 254 LETFVMDGNELQVLPDSL--FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNR 81
L+ ++ L+ + S F LRNLT + L NN I+ I+ + +G + LDL +N
Sbjct: 482 LQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNN 541
Query: 80 LA 75
LA
Sbjct: 542 LA 543
Score = 52.8 bits (121), Expect = 9e-07
Identities = 55/197 (27%), Positives = 89/197 (45%), Gaps = 10/197 (5%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLD---LSSIREL 426
+ N L + F ++ E+ + +N +K F L TL L LSS +
Sbjct: 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLR--GQTQLTSLTLSYNAVAELAPELFADLRAL 252
+ + N L+ L L+ N+++AL L + L L LS N + E +P F + L
Sbjct: 166 TQVQLEN--LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRL 223
Query: 251 ETFVMDGNEL-QVLPDSLFSGLRN--LTTVSLRNNKISVISMNTFQGA--TSIRTLDLSY 87
++ +L L + L L N + +SL N+++S S TF G T++ LDLSY
Sbjct: 224 FGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
Query: 86 NRLAFAPDSLYSPLNQL 36
N L + ++ L QL
Sbjct: 284 NNLNVVGNDSFAWLPQL 300
Score = 49.2 bits (112), Expect = 1e-05
Identities = 43/165 (26%), Positives = 74/165 (44%), Gaps = 10/165 (6%)
Frame = -3
Query: 485 FSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRAL--------PRSVLRGQ 333
F L L L L ++I + ++ + L L L N L L P L+G
Sbjct: 502 FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGL 561
Query: 332 TQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNK 153
+ L L L N E+ E+F DL L+ + N L LP S+F+ +L +++L+ N
Sbjct: 562 SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNL 621
Query: 152 ISVISMNTFQGA-TSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQT 21
I+ + F A ++ LD+ +N +S+ +N +++ T
Sbjct: 622 ITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHT 666
Score = 44.4 bits (100), Expect = 3e-04
Identities = 41/181 (22%), Positives = 80/181 (44%), Gaps = 8/181 (4%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+M NS + + + F ++ + +S+N + K L L+ L L + I+ L E
Sbjct: 130 LMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSE 189
Query: 416 ---FISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVA-ELAPELFADLR--A 255
+NS L+ L L+ NQ++ +L L L+ + L +L +L +
Sbjct: 190 ELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTS 249
Query: 254 LETFVMDGNELQVLPDSLFSGLR--NLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNR 81
+ + ++L ++ F GL+ NLT + L N ++V+ ++F + L YN
Sbjct: 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
Query: 80 L 78
+
Sbjct: 310 I 310
>BC096333-1|AAH96333.1| 904|Homo sapiens toll-like receptor 3
protein.
Length = 904
Score = 79.8 bits (188), Expect = 7e-15
Identities = 51/145 (35%), Positives = 77/145 (53%)
Frame = -3
Query: 437 IRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 258
+ ++P++ +N + L+L NQLR LP + +QLTSL + +N +++L PEL L
Sbjct: 42 LTQVPDDLPTN--ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLP 99
Query: 257 ALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
L+ + NEL L D F+ NLT + L +N I I N F ++ TLDLS+N L
Sbjct: 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
Query: 77 AFAPDSLYSPLNQLHKLQTLTLAWN 3
+ + QL LQ L L+ N
Sbjct: 160 S---STKLGTQVQLENLQELLLSNN 181
Score = 59.3 bits (137), Expect = 1e-08
Identities = 52/182 (28%), Positives = 85/182 (46%), Gaps = 8/182 (4%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPL--TLKEAVFSNLP--ALRTLQLDLSSIRE 429
M N + S +F GL +++ + +SN+ TL F +L L L L + I +
Sbjct: 362 MEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISK 421
Query: 428 LPEEFIS-NSPLRTLSLARNQL-RALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRA 255
+ + S L L L N++ + L RG + + LSYN +L FA + +
Sbjct: 422 IESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPS 481
Query: 254 LETFVMDGNELQVLPDSL--FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNR 81
L+ ++ L+ + S F LRNLT + L NN I+ I+ + +G + LDL +N
Sbjct: 482 LQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNN 541
Query: 80 LA 75
LA
Sbjct: 542 LA 543
Score = 52.8 bits (121), Expect = 9e-07
Identities = 55/197 (27%), Positives = 89/197 (45%), Gaps = 10/197 (5%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLD---LSSIREL 426
+ N L + F ++ E+ + +N +K F L TL L LSS +
Sbjct: 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLR--GQTQLTSLTLSYNAVAELAPELFADLRAL 252
+ + N L+ L L+ N+++AL L + L L LS N + E +P F + L
Sbjct: 166 TQVQLEN--LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRL 223
Query: 251 ETFVMDGNEL-QVLPDSLFSGLRN--LTTVSLRNNKISVISMNTFQGA--TSIRTLDLSY 87
++ +L L + L L N + +SL N+++S S TF G T++ LDLSY
Sbjct: 224 FGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
Query: 86 NRLAFAPDSLYSPLNQL 36
N L + ++ L QL
Sbjct: 284 NNLNVVGNDSFAWLPQL 300
Score = 49.2 bits (112), Expect = 1e-05
Identities = 43/165 (26%), Positives = 74/165 (44%), Gaps = 10/165 (6%)
Frame = -3
Query: 485 FSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRAL--------PRSVLRGQ 333
F L L L L ++I + ++ + L L L N L L P L+G
Sbjct: 502 FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGL 561
Query: 332 TQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNK 153
+ L L L N E+ E+F DL L+ + N L LP S+F+ +L +++L+ N
Sbjct: 562 SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNL 621
Query: 152 ISVISMNTFQGA-TSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQT 21
I+ + F A ++ LD+ +N +S+ +N +++ T
Sbjct: 622 ITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHT 666
Score = 44.4 bits (100), Expect = 3e-04
Identities = 41/181 (22%), Positives = 80/181 (44%), Gaps = 8/181 (4%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+M NS + + + F ++ + +S+N + K L L+ L L + I+ L E
Sbjct: 130 LMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSE 189
Query: 416 ---FISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVA-ELAPELFADLR--A 255
+NS L+ L L+ NQ++ +L L L+ + L +L +L +
Sbjct: 190 ELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTS 249
Query: 254 LETFVMDGNELQVLPDSLFSGLR--NLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNR 81
+ + ++L ++ F GL+ NLT + L N ++V+ ++F + L YN
Sbjct: 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
Query: 80 L 78
+
Sbjct: 310 I 310
>BC094737-1|AAH94737.1| 904|Homo sapiens toll-like receptor 3
protein.
Length = 904
Score = 79.8 bits (188), Expect = 7e-15
Identities = 51/145 (35%), Positives = 77/145 (53%)
Frame = -3
Query: 437 IRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 258
+ ++P++ +N + L+L NQLR LP + +QLTSL + +N +++L PEL L
Sbjct: 42 LTQVPDDLPTN--ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLP 99
Query: 257 ALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
L+ + NEL L D F+ NLT + L +N I I N F ++ TLDLS+N L
Sbjct: 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
Query: 77 AFAPDSLYSPLNQLHKLQTLTLAWN 3
+ + QL LQ L L+ N
Sbjct: 160 S---STKLGTQVQLENLQELLLSNN 181
Score = 59.3 bits (137), Expect = 1e-08
Identities = 52/182 (28%), Positives = 85/182 (46%), Gaps = 8/182 (4%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPL--TLKEAVFSNLP--ALRTLQLDLSSIRE 429
M N + S +F GL +++ + +SN+ TL F +L L L L + I +
Sbjct: 362 MEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISK 421
Query: 428 LPEEFIS-NSPLRTLSLARNQL-RALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRA 255
+ + S L L L N++ + L RG + + LSYN +L FA + +
Sbjct: 422 IESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPS 481
Query: 254 LETFVMDGNELQVLPDSL--FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNR 81
L+ ++ L+ + S F LRNLT + L NN I+ I+ + +G + LDL +N
Sbjct: 482 LQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNN 541
Query: 80 LA 75
LA
Sbjct: 542 LA 543
Score = 52.8 bits (121), Expect = 9e-07
Identities = 55/197 (27%), Positives = 89/197 (45%), Gaps = 10/197 (5%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLD---LSSIREL 426
+ N L + F ++ E+ + +N +K F L TL L LSS +
Sbjct: 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLR--GQTQLTSLTLSYNAVAELAPELFADLRAL 252
+ + N L+ L L+ N+++AL L + L L LS N + E +P F + L
Sbjct: 166 TQVQLEN--LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRL 223
Query: 251 ETFVMDGNEL-QVLPDSLFSGLRN--LTTVSLRNNKISVISMNTFQGA--TSIRTLDLSY 87
++ +L L + L L N + +SL N+++S S TF G T++ LDLSY
Sbjct: 224 FGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
Query: 86 NRLAFAPDSLYSPLNQL 36
N L + ++ L QL
Sbjct: 284 NNLNVVGNDSFAWLPQL 300
Score = 49.2 bits (112), Expect = 1e-05
Identities = 43/165 (26%), Positives = 74/165 (44%), Gaps = 10/165 (6%)
Frame = -3
Query: 485 FSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRAL--------PRSVLRGQ 333
F L L L L ++I + ++ + L L L N L L P L+G
Sbjct: 502 FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGL 561
Query: 332 TQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNK 153
+ L L L N E+ E+F DL L+ + N L LP S+F+ +L +++L+ N
Sbjct: 562 SHLHILNLESNGFNEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNL 621
Query: 152 ISVISMNTFQGA-TSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQT 21
I+ + F A ++ LD+ +N +S+ +N +++ T
Sbjct: 622 ITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHT 666
Score = 44.4 bits (100), Expect = 3e-04
Identities = 41/181 (22%), Positives = 80/181 (44%), Gaps = 8/181 (4%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+M NS + + + F ++ + +S+N + K L L+ L L + I+ L E
Sbjct: 130 LMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSE 189
Query: 416 ---FISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVA-ELAPELFADLR--A 255
+NS L+ L L+ NQ++ +L L L+ + L +L +L +
Sbjct: 190 ELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTS 249
Query: 254 LETFVMDGNELQVLPDSLFSGLR--NLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNR 81
+ + ++L ++ F GL+ NLT + L N ++V+ ++F + L YN
Sbjct: 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
Query: 80 L 78
+
Sbjct: 310 I 310
Score = 29.5 bits (63), Expect = 9.5
Identities = 16/57 (28%), Positives = 31/57 (54%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
N F + E+F+ L ++ I + N TL +VF+N +L++L L + I + ++
Sbjct: 572 NGFNEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 628
>BC059372-1|AAH59372.1| 870|Homo sapiens TLR3 protein protein.
Length = 870
Score = 79.8 bits (188), Expect = 7e-15
Identities = 51/145 (35%), Positives = 77/145 (53%)
Frame = -3
Query: 437 IRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 258
+ ++P++ +N + L+L NQLR LP + +QLTSL + +N +++L PEL L
Sbjct: 42 LTQVPDDLPTN--ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLP 99
Query: 257 ALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
L+ + NEL L D F+ NLT + L +N I I N F ++ TLDLS+N L
Sbjct: 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
Query: 77 AFAPDSLYSPLNQLHKLQTLTLAWN 3
+ + QL LQ L L+ N
Sbjct: 160 S---STKLGTQVQLENLQELLLSNN 181
Score = 59.3 bits (137), Expect = 1e-08
Identities = 52/182 (28%), Positives = 85/182 (46%), Gaps = 8/182 (4%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPL--TLKEAVFSNLP--ALRTLQLDLSSIRE 429
M N + S +F GL +++ + +SN+ TL F +L L L L + I +
Sbjct: 362 MEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISK 421
Query: 428 LPEEFIS-NSPLRTLSLARNQL-RALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRA 255
+ + S L L L N++ + L RG + + LSYN +L FA + +
Sbjct: 422 IESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPS 481
Query: 254 LETFVMDGNELQVLPDSL--FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNR 81
L+ ++ L+ + S F LRNLT + L NN I+ I+ + +G + LDL +N
Sbjct: 482 LQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNN 541
Query: 80 LA 75
LA
Sbjct: 542 LA 543
Score = 52.8 bits (121), Expect = 9e-07
Identities = 55/197 (27%), Positives = 89/197 (45%), Gaps = 10/197 (5%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLD---LSSIREL 426
+ N L + F ++ E+ + +N +K F L TL L LSS +
Sbjct: 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLR--GQTQLTSLTLSYNAVAELAPELFADLRAL 252
+ + N L+ L L+ N+++AL L + L L LS N + E +P F + L
Sbjct: 166 TQVQLEN--LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRL 223
Query: 251 ETFVMDGNEL-QVLPDSLFSGLRN--LTTVSLRNNKISVISMNTFQGA--TSIRTLDLSY 87
++ +L L + L L N + +SL N+++S S TF G T++ LDLSY
Sbjct: 224 FGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
Query: 86 NRLAFAPDSLYSPLNQL 36
N L + ++ L QL
Sbjct: 284 NNLNVVGNDSFAWLPQL 300
Score = 49.2 bits (112), Expect = 1e-05
Identities = 43/165 (26%), Positives = 74/165 (44%), Gaps = 10/165 (6%)
Frame = -3
Query: 485 FSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRAL--------PRSVLRGQ 333
F L L L L ++I + ++ + L L L N L L P L+G
Sbjct: 502 FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGL 561
Query: 332 TQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNK 153
+ L L L N E+ E+F DL L+ + N L LP S+F+ +L +++L+ N
Sbjct: 562 SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNL 621
Query: 152 ISVISMNTFQGA-TSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQT 21
I+ + F A ++ LD+ +N +S+ +N +++ T
Sbjct: 622 ITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHT 666
Score = 44.4 bits (100), Expect = 3e-04
Identities = 41/181 (22%), Positives = 80/181 (44%), Gaps = 8/181 (4%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+M NS + + + F ++ + +S+N + K L L+ L L + I+ L E
Sbjct: 130 LMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSE 189
Query: 416 ---FISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVA-ELAPELFADLR--A 255
+NS L+ L L+ NQ++ +L L L+ + L +L +L +
Sbjct: 190 ELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTS 249
Query: 254 LETFVMDGNELQVLPDSLFSGLR--NLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNR 81
+ + ++L ++ F GL+ NLT + L N ++V+ ++F + L YN
Sbjct: 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
Query: 80 L 78
+
Sbjct: 310 I 310
>BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2
(Drosophila) protein.
Length = 1529
Score = 79.4 bits (187), Expect = 9e-15
Identities = 47/141 (33%), Positives = 76/141 (53%), Gaps = 2/141 (1%)
Frame = -3
Query: 419 EFISNSP--LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALET 246
E +N P + + L +N ++ +P +L + LS N ++ELAP+ F LR+L +
Sbjct: 293 EIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNS 352
Query: 245 FVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAP 66
V+ GN++ LP SLF GL +L + L NKI+ + ++ FQ ++ L L N+L
Sbjct: 353 LVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIA 412
Query: 65 DSLYSPLNQLHKLQTLTLAWN 3
+SP L +QT+ LA N
Sbjct: 413 KGTFSP---LRAIQTMHLAQN 430
Score = 69.3 bits (162), Expect = 1e-11
Identities = 40/138 (28%), Positives = 64/138 (46%)
Frame = -3
Query: 440 SIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADL 261
++R +P N+ L L N + + ++ G L L L N ++ + F DL
Sbjct: 45 ALRSVPRNIPRNT--ERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDL 102
Query: 260 RALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNR 81
+ LE ++ N LQ+ P+ LF G L + L N+I I F+GA I+ L L YN+
Sbjct: 103 KELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQ 162
Query: 80 LAFAPDSLYSPLNQLHKL 27
++ D + L L L
Sbjct: 163 ISCIEDGAFRALRDLEVL 180
Score = 64.9 bits (151), Expect = 2e-10
Identities = 42/154 (27%), Positives = 71/154 (46%), Gaps = 1/154 (0%)
Frame = -3
Query: 536 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRA 360
+ + ++ N + + F+ L LR LQL + I + F L L L RN L+
Sbjct: 58 ERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQL 117
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
P + G +L L LS N + + + F ++ +D N++ + D F LR+L
Sbjct: 118 FPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDL 177
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
++L NN I+ +S+ +F +RT L N L
Sbjct: 178 EVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 57.6 bits (133), Expect = 3e-08
Identities = 34/130 (26%), Positives = 62/130 (47%), Gaps = 1/130 (0%)
Frame = -3
Query: 389 LSLARNQLRALPRS-VLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVL 213
L L N+ L + + + QL + S N + ++ F + ++ N L+ +
Sbjct: 538 LRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENV 597
Query: 212 PDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLH 33
+F GL +L T+ LR+N+I+ + ++F G +S+R L L N++ + + LH
Sbjct: 598 QHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAF---DTLH 654
Query: 32 KLQTLTLAWN 3
L TL L N
Sbjct: 655 SLSTLNLLAN 664
Score = 56.4 bits (130), Expect = 7e-08
Identities = 29/103 (28%), Positives = 53/103 (51%)
Frame = -3
Query: 458 LQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAP 279
L LD + +P+E + L + L+ N++ L TQL +L LSYN + + P
Sbjct: 759 LYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPP 818
Query: 278 ELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKI 150
F L++L + GN++ V+P+ F+ L L+ +++ N +
Sbjct: 819 RTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPL 861
Score = 56.4 bits (130), Expect = 7e-08
Identities = 32/104 (30%), Positives = 54/104 (51%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
L L NQ +P+ L LT + LS N ++ L+ + F+++ L T ++ N L+ +P
Sbjct: 759 LYLDGNQFTLVPKE-LSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIP 817
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
F GL++L +SL N ISV+ F +++ L + N L
Sbjct: 818 PRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPL 861
Score = 55.2 bits (127), Expect = 2e-07
Identities = 29/78 (37%), Positives = 42/78 (53%)
Frame = -3
Query: 260 RALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNR 81
R + +DGN+ ++P L S ++LT + L NN+IS +S +F T + TL LSYNR
Sbjct: 754 RDVTELYLDGNQFTLVPKEL-SNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNR 812
Query: 80 LAFAPDSLYSPLNQLHKL 27
L P + L L L
Sbjct: 813 LRCIPPRTFDGLKSLRLL 830
Score = 43.6 bits (98), Expect = 5e-04
Identities = 30/122 (24%), Positives = 55/122 (45%), Gaps = 2/122 (1%)
Frame = -3
Query: 587 NSFRYLDSE-IFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-F 414
N F L++ IF+ L +++I SNN ++E F + + L + + + + F
Sbjct: 543 NEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMF 602
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
L+TL L N++ + G + + L+L N + +AP F L +L T +
Sbjct: 603 KGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLL 662
Query: 233 GN 228
N
Sbjct: 663 AN 664
Score = 42.7 bits (96), Expect = 0.001
Identities = 30/97 (30%), Positives = 43/97 (44%), Gaps = 1/97 (1%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFI 411
N F + E+ H+ I +SNN TL FSN+ L TL L + +R + P F
Sbjct: 764 NQFTLVPKEL-SNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFD 822
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYN 300
LR LSL N + +P + L+ L + N
Sbjct: 823 GLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGAN 859
Score = 41.9 bits (94), Expect = 0.002
Identities = 33/122 (27%), Positives = 55/122 (45%), Gaps = 1/122 (0%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-F 414
+N+ + + F ++ I +SNN L F L +L +L L + I ELP+ F
Sbjct: 309 QNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLF 368
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
L+ L L N++ L + L L+L N + +A F+ LRA++T +
Sbjct: 369 EGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLA 428
Query: 233 GN 228
N
Sbjct: 429 QN 430
Score = 36.7 bits (81), Expect = 0.063
Identities = 46/197 (23%), Positives = 84/197 (42%), Gaps = 10/197 (5%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI-----RELP 423
N ++ FR L ++ + ++NN L A F+++P LRT +L +++
Sbjct: 161 NQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNLYCDCHLAWL 220
Query: 422 EEFISNSP---LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRAL 252
+++ P L T + + LR + ++ + + S S+ A + A
Sbjct: 221 SDWLRQRPRVGLYTQCMGPSHLRGHNVAEVQKREFVCSGHQSFMAPSCSVLHCPAACTCS 280
Query: 251 ETFV-MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLA 75
V G L +P +L +T + L N I VI F +R +DLS N+++
Sbjct: 281 NNIVDCRGKGLTEIPTNL---PETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQIS 337
Query: 74 -FAPDSLYSPLNQLHKL 27
APD+ + L L+ L
Sbjct: 338 ELAPDA-FQGLRSLNSL 353
>BC045113-1|AAH45113.1| 522|Homo sapiens LRRTM1 protein protein.
Length = 522
Score = 79.4 bits (187), Expect = 9e-15
Identities = 50/159 (31%), Positives = 79/159 (49%), Gaps = 1/159 (0%)
Frame = -3
Query: 500 LKEAVFSNLPALRTLQLDLSSIRELP-EEFISNSPLRTLSLARNQLRALPRSVLRGQTQL 324
L+ F+ L L L LD + I + + F ++ L+L+ NQ+ LP + R L
Sbjct: 80 LRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNL 139
Query: 323 TSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISV 144
S+ LSYN + LAP+LF LR L T M N +Q +P +F R+L + + N++
Sbjct: 140 RSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKS 199
Query: 143 ISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
++ N+F G + L L +N L + + L LH L
Sbjct: 200 LARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSL 238
Score = 74.5 bits (175), Expect = 3e-13
Identities = 50/178 (28%), Positives = 90/178 (50%), Gaps = 1/178 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
NS L + F GL + + + +N +++ F L ++ L L + I +LP
Sbjct: 75 NSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFR 134
Query: 407 NSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
P LR++ L+ N+L+AL + G +LT+L + NA+ + +F D R+L+ +
Sbjct: 135 PMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGY 194
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
N+L+ L + F+GL LT + L +N + ++ F S+ +L L N++A SL
Sbjct: 195 NQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVAIVVSSL 252
Score = 66.1 bits (154), Expect = 9e-11
Identities = 40/143 (27%), Positives = 65/143 (45%)
Frame = -3
Query: 464 RTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAEL 285
R L + ++ E P S L LSL N L L G QLT L L +N + +
Sbjct: 48 RLLYCEALNLTEAPHNL---SGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSV 104
Query: 284 APELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIR 105
+ F LR ++ + N++ LP++ F + NL +V L NK+ ++ + F G +
Sbjct: 105 QGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLT 164
Query: 104 TLDLSYNRLAFAPDSLYSPLNQL 36
TL + N + F P ++ L
Sbjct: 165 TLHMRANAIQFVPVRIFQDCRSL 187
Score = 59.7 bits (138), Expect = 8e-09
Identities = 37/109 (33%), Positives = 59/109 (54%), Gaps = 1/109 (0%)
Frame = -3
Query: 326 LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKIS 147
L L+L YN+++EL F L L +D N + + F LR + ++L +N+I+
Sbjct: 67 LLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQIT 126
Query: 146 VISMNTFQGATSIRTLDLSYNRL-AFAPDSLYSPLNQLHKLQTLTLAWN 3
+ TF+ ++R++DLSYN+L A APD + L KL TL + N
Sbjct: 127 QLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHG----LRKLTTLHMRAN 171
>AY358310-1|AAQ88677.1| 522|Homo sapiens DFLL675 protein.
Length = 522
Score = 79.4 bits (187), Expect = 9e-15
Identities = 50/159 (31%), Positives = 79/159 (49%), Gaps = 1/159 (0%)
Frame = -3
Query: 500 LKEAVFSNLPALRTLQLDLSSIRELP-EEFISNSPLRTLSLARNQLRALPRSVLRGQTQL 324
L+ F+ L L L LD + I + + F ++ L+L+ NQ+ LP + R L
Sbjct: 80 LRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNL 139
Query: 323 TSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISV 144
S+ LSYN + LAP+LF LR L T M N +Q +P +F R+L + + N++
Sbjct: 140 RSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKS 199
Query: 143 ISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
++ N+F G + L L +N L + + L LH L
Sbjct: 200 LARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSL 238
Score = 74.5 bits (175), Expect = 3e-13
Identities = 50/178 (28%), Positives = 90/178 (50%), Gaps = 1/178 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
NS L + F GL + + + +N +++ F L ++ L L + I +LP
Sbjct: 75 NSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFR 134
Query: 407 NSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
P LR++ L+ N+L+AL + G +LT+L + NA+ + +F D R+L+ +
Sbjct: 135 PMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGY 194
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
N+L+ L + F+GL LT + L +N + ++ F S+ +L L N++A SL
Sbjct: 195 NQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVAIVVSSL 252
Score = 66.1 bits (154), Expect = 9e-11
Identities = 40/143 (27%), Positives = 65/143 (45%)
Frame = -3
Query: 464 RTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAEL 285
R L + ++ E P S L LSL N L L G QLT L L +N + +
Sbjct: 48 RLLYCEALNLTEAPHNL---SGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSV 104
Query: 284 APELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIR 105
+ F LR ++ + N++ LP++ F + NL +V L NK+ ++ + F G +
Sbjct: 105 QGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLT 164
Query: 104 TLDLSYNRLAFAPDSLYSPLNQL 36
TL + N + F P ++ L
Sbjct: 165 TLHMRANAIQFVPVRIFQDCRSL 187
Score = 59.7 bits (138), Expect = 8e-09
Identities = 37/109 (33%), Positives = 59/109 (54%), Gaps = 1/109 (0%)
Frame = -3
Query: 326 LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKIS 147
L L+L YN+++EL F L L +D N + + F LR + ++L +N+I+
Sbjct: 67 LLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQIT 126
Query: 146 VISMNTFQGATSIRTLDLSYNRL-AFAPDSLYSPLNQLHKLQTLTLAWN 3
+ TF+ ++R++DLSYN+L A APD + L KL TL + N
Sbjct: 127 QLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHG----LRKLTTLHMRAN 171
>AY182024-1|AAO67545.1| 522|Homo sapiens leucine-rich repeat
transmembrane neuronal 1 protein protein.
Length = 522
Score = 79.4 bits (187), Expect = 9e-15
Identities = 50/159 (31%), Positives = 79/159 (49%), Gaps = 1/159 (0%)
Frame = -3
Query: 500 LKEAVFSNLPALRTLQLDLSSIRELP-EEFISNSPLRTLSLARNQLRALPRSVLRGQTQL 324
L+ F+ L L L LD + I + + F ++ L+L+ NQ+ LP + R L
Sbjct: 80 LRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNL 139
Query: 323 TSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISV 144
S+ LSYN + LAP+LF LR L T M N +Q +P +F R+L + + N++
Sbjct: 140 RSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKS 199
Query: 143 ISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
++ N+F G + L L +N L + + L LH L
Sbjct: 200 LARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSL 238
Score = 74.5 bits (175), Expect = 3e-13
Identities = 50/178 (28%), Positives = 90/178 (50%), Gaps = 1/178 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
NS L + F GL + + + +N +++ F L ++ L L + I +LP
Sbjct: 75 NSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFR 134
Query: 407 NSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
P LR++ L+ N+L+AL + G +LT+L + NA+ + +F D R+L+ +
Sbjct: 135 PMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGY 194
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
N+L+ L + F+GL LT + L +N + ++ F S+ +L L N++A SL
Sbjct: 195 NQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVAIVVSSL 252
Score = 66.1 bits (154), Expect = 9e-11
Identities = 40/143 (27%), Positives = 65/143 (45%)
Frame = -3
Query: 464 RTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAEL 285
R L + ++ E P S L LSL N L L G QLT L L +N + +
Sbjct: 48 RLLYCEALNLTEAPHNL---SGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSV 104
Query: 284 APELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIR 105
+ F LR ++ + N++ LP++ F + NL +V L NK+ ++ + F G +
Sbjct: 105 QGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLT 164
Query: 104 TLDLSYNRLAFAPDSLYSPLNQL 36
TL + N + F P ++ L
Sbjct: 165 TLHMRANAIQFVPVRIFQDCRSL 187
Score = 59.7 bits (138), Expect = 8e-09
Identities = 37/109 (33%), Positives = 59/109 (54%), Gaps = 1/109 (0%)
Frame = -3
Query: 326 LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKIS 147
L L+L YN+++EL F L L +D N + + F LR + ++L +N+I+
Sbjct: 67 LLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQIT 126
Query: 146 VISMNTFQGATSIRTLDLSYNRL-AFAPDSLYSPLNQLHKLQTLTLAWN 3
+ TF+ ++R++DLSYN+L A APD + L KL TL + N
Sbjct: 127 QLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHG----LRKLTTLHMRAN 171
>AK056644-1|BAB71240.1| 522|Homo sapiens protein ( Homo sapiens
cDNA FLJ32082 fis, clone OCBBF2000231, weakly similar to
PHOSPHOLIPASE A2 INHIBITOR SUBUNIT B PRECURSOR. ).
Length = 522
Score = 79.4 bits (187), Expect = 9e-15
Identities = 50/159 (31%), Positives = 79/159 (49%), Gaps = 1/159 (0%)
Frame = -3
Query: 500 LKEAVFSNLPALRTLQLDLSSIRELP-EEFISNSPLRTLSLARNQLRALPRSVLRGQTQL 324
L+ F+ L L L LD + I + + F ++ L+L+ NQ+ LP + R L
Sbjct: 80 LRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNL 139
Query: 323 TSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISV 144
S+ LSYN + LAP+LF LR L T M N +Q +P +F R+L + + N++
Sbjct: 140 RSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKS 199
Query: 143 ISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
++ N+F G + L L +N L + + L LH L
Sbjct: 200 LARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSL 238
Score = 74.5 bits (175), Expect = 3e-13
Identities = 50/178 (28%), Positives = 90/178 (50%), Gaps = 1/178 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
NS L + F GL + + + +N +++ F L ++ L L + I +LP
Sbjct: 75 NSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFR 134
Query: 407 NSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
P LR++ L+ N+L+AL + G +LT+L + NA+ + +F D R+L+ +
Sbjct: 135 PMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGY 194
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
N+L+ L + F+GL LT + L +N + ++ F S+ +L L N++A SL
Sbjct: 195 NQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVAIVVSSL 252
Score = 66.1 bits (154), Expect = 9e-11
Identities = 40/143 (27%), Positives = 65/143 (45%)
Frame = -3
Query: 464 RTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAEL 285
R L + ++ E P S L LSL N L L G QLT L L +N + +
Sbjct: 48 RLLYCEALNLTEAPHNL---SGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSV 104
Query: 284 APELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIR 105
+ F LR ++ + N++ LP++ F + NL +V L NK+ ++ + F G +
Sbjct: 105 QGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLT 164
Query: 104 TLDLSYNRLAFAPDSLYSPLNQL 36
TL + N + F P ++ L
Sbjct: 165 TLHMRANAIQFVPVRIFQDCRSL 187
Score = 59.7 bits (138), Expect = 8e-09
Identities = 37/109 (33%), Positives = 59/109 (54%), Gaps = 1/109 (0%)
Frame = -3
Query: 326 LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKIS 147
L L+L YN+++EL F L L +D N + + F LR + ++L +N+I+
Sbjct: 67 LLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQIT 126
Query: 146 VISMNTFQGATSIRTLDLSYNRL-AFAPDSLYSPLNQLHKLQTLTLAWN 3
+ TF+ ++R++DLSYN+L A APD + L KL TL + N
Sbjct: 127 QLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHG----LRKLTTLHMRAN 171
>AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein.
Length = 1525
Score = 79.4 bits (187), Expect = 9e-15
Identities = 47/141 (33%), Positives = 76/141 (53%), Gaps = 2/141 (1%)
Frame = -3
Query: 419 EFISNSP--LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALET 246
E +N P + + L +N ++ +P +L + LS N ++ELAP+ F LR+L +
Sbjct: 297 EIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNS 356
Query: 245 FVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAP 66
V+ GN++ LP SLF GL +L + L NKI+ + ++ FQ ++ L L N+L
Sbjct: 357 LVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIA 416
Query: 65 DSLYSPLNQLHKLQTLTLAWN 3
+SP L +QT+ LA N
Sbjct: 417 KGTFSP---LRAIQTMHLAQN 434
Score = 69.3 bits (162), Expect = 1e-11
Identities = 40/138 (28%), Positives = 64/138 (46%)
Frame = -3
Query: 440 SIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADL 261
++R +P N+ L L N + + ++ G L L L N ++ + F DL
Sbjct: 45 ALRSVPRNIPRNT--ERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDL 102
Query: 260 RALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNR 81
+ LE ++ N LQ+ P+ LF G L + L N+I I F+GA I+ L L YN+
Sbjct: 103 KELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQ 162
Query: 80 LAFAPDSLYSPLNQLHKL 27
++ D + L L L
Sbjct: 163 ISCIEDGAFRALRDLEVL 180
Score = 64.9 bits (151), Expect = 2e-10
Identities = 42/154 (27%), Positives = 71/154 (46%), Gaps = 1/154 (0%)
Frame = -3
Query: 536 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRA 360
+ + ++ N + + F+ L LR LQL + I + F L L L RN L+
Sbjct: 58 ERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQL 117
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
P + G +L L LS N + + + F ++ +D N++ + D F LR+L
Sbjct: 118 FPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDL 177
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
++L NN I+ +S+ +F +RT L N L
Sbjct: 178 EVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 57.6 bits (133), Expect = 3e-08
Identities = 34/130 (26%), Positives = 62/130 (47%), Gaps = 1/130 (0%)
Frame = -3
Query: 389 LSLARNQLRALPRS-VLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVL 213
L L N+ L + + + QL + S N + ++ F + ++ N L+ +
Sbjct: 534 LRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENV 593
Query: 212 PDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLH 33
+F GL +L T+ LR+N+I+ + ++F G +S+R L L N++ + + LH
Sbjct: 594 QHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAF---DTLH 650
Query: 32 KLQTLTLAWN 3
L TL L N
Sbjct: 651 SLSTLNLLAN 660
Score = 56.4 bits (130), Expect = 7e-08
Identities = 29/103 (28%), Positives = 53/103 (51%)
Frame = -3
Query: 458 LQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAP 279
L LD + +P+E + L + L+ N++ L TQL +L LSYN + + P
Sbjct: 755 LYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPP 814
Query: 278 ELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKI 150
F L++L + GN++ V+P+ F+ L L+ +++ N +
Sbjct: 815 RTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPL 857
Score = 56.4 bits (130), Expect = 7e-08
Identities = 32/104 (30%), Positives = 54/104 (51%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
L L NQ +P+ L LT + LS N ++ L+ + F+++ L T ++ N L+ +P
Sbjct: 755 LYLDGNQFTLVPKE-LSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIP 813
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
F GL++L +SL N ISV+ F +++ L + N L
Sbjct: 814 PRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPL 857
Score = 55.2 bits (127), Expect = 2e-07
Identities = 29/78 (37%), Positives = 42/78 (53%)
Frame = -3
Query: 260 RALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNR 81
R + +DGN+ ++P L S ++LT + L NN+IS +S +F T + TL LSYNR
Sbjct: 750 RDVTELYLDGNQFTLVPKEL-SNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNR 808
Query: 80 LAFAPDSLYSPLNQLHKL 27
L P + L L L
Sbjct: 809 LRCIPPRTFDGLKSLRLL 826
Score = 43.6 bits (98), Expect = 5e-04
Identities = 30/122 (24%), Positives = 55/122 (45%), Gaps = 2/122 (1%)
Frame = -3
Query: 587 NSFRYLDSE-IFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-F 414
N F L++ IF+ L +++I SNN ++E F + + L + + + + F
Sbjct: 539 NEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMF 598
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
L+TL L N++ + G + + L+L N + +AP F L +L T +
Sbjct: 599 KGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLL 658
Query: 233 GN 228
N
Sbjct: 659 AN 660
Score = 42.7 bits (96), Expect = 0.001
Identities = 30/97 (30%), Positives = 43/97 (44%), Gaps = 1/97 (1%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFI 411
N F + E+ H+ I +SNN TL FSN+ L TL L + +R + P F
Sbjct: 760 NQFTLVPKEL-SNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFD 818
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYN 300
LR LSL N + +P + L+ L + N
Sbjct: 819 GLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGAN 855
Score = 41.9 bits (94), Expect = 0.002
Identities = 33/122 (27%), Positives = 55/122 (45%), Gaps = 1/122 (0%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-F 414
+N+ + + F ++ I +SNN L F L +L +L L + I ELP+ F
Sbjct: 313 QNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLF 372
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
L+ L L N++ L + L L+L N + +A F+ LRA++T +
Sbjct: 373 EGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLA 432
Query: 233 GN 228
N
Sbjct: 433 QN 434
Score = 30.7 bits (66), Expect = 4.1
Identities = 14/51 (27%), Positives = 28/51 (54%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI 435
N ++ FR L ++ + ++NN L A F+++P LRT +L +++
Sbjct: 161 NQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
>AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellular
slit protein Slit2 protein.
Length = 1521
Score = 79.4 bits (187), Expect = 9e-15
Identities = 47/141 (33%), Positives = 76/141 (53%), Gaps = 2/141 (1%)
Frame = -3
Query: 419 EFISNSP--LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALET 246
E +N P + + L +N ++ +P +L + LS N ++ELAP+ F LR+L +
Sbjct: 293 EIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNS 352
Query: 245 FVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAP 66
V+ GN++ LP SLF GL +L + L NKI+ + ++ FQ ++ L L N+L
Sbjct: 353 LVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIA 412
Query: 65 DSLYSPLNQLHKLQTLTLAWN 3
+SP L +QT+ LA N
Sbjct: 413 KGTFSP---LRAIQTMHLAQN 430
Score = 69.3 bits (162), Expect = 1e-11
Identities = 40/138 (28%), Positives = 64/138 (46%)
Frame = -3
Query: 440 SIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADL 261
++R +P N+ L L N + + ++ G L L L N ++ + F DL
Sbjct: 45 ALRSVPRNIPRNT--ERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDL 102
Query: 260 RALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNR 81
+ LE ++ N LQ+ P+ LF G L + L N+I I F+GA I+ L L YN+
Sbjct: 103 KELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQ 162
Query: 80 LAFAPDSLYSPLNQLHKL 27
++ D + L L L
Sbjct: 163 ISCIEDGAFRALRDLEVL 180
Score = 64.9 bits (151), Expect = 2e-10
Identities = 42/154 (27%), Positives = 71/154 (46%), Gaps = 1/154 (0%)
Frame = -3
Query: 536 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRA 360
+ + ++ N + + F+ L LR LQL + I + F L L L RN L+
Sbjct: 58 ERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQL 117
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
P + G +L L LS N + + + F ++ +D N++ + D F LR+L
Sbjct: 118 FPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDL 177
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
++L NN I+ +S+ +F +RT L N L
Sbjct: 178 EVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 56.4 bits (130), Expect = 7e-08
Identities = 29/103 (28%), Positives = 53/103 (51%)
Frame = -3
Query: 458 LQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAP 279
L LD + +P+E + L + L+ N++ L TQL +L LSYN + + P
Sbjct: 751 LYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPP 810
Query: 278 ELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKI 150
F L++L + GN++ V+P+ F+ L L+ +++ N +
Sbjct: 811 RTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPL 853
Score = 56.4 bits (130), Expect = 7e-08
Identities = 32/104 (30%), Positives = 54/104 (51%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
L L NQ +P+ L LT + LS N ++ L+ + F+++ L T ++ N L+ +P
Sbjct: 751 LYLDGNQFTLVPKE-LSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIP 809
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
F GL++L +SL N ISV+ F +++ L + N L
Sbjct: 810 PRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPL 853
Score = 55.2 bits (127), Expect = 2e-07
Identities = 29/78 (37%), Positives = 42/78 (53%)
Frame = -3
Query: 260 RALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNR 81
R + +DGN+ ++P L S ++LT + L NN+IS +S +F T + TL LSYNR
Sbjct: 746 RDVTELYLDGNQFTLVPKEL-SNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNR 804
Query: 80 LAFAPDSLYSPLNQLHKL 27
L P + L L L
Sbjct: 805 LRCIPPRTFDGLKSLRLL 822
Score = 52.4 bits (120), Expect = 1e-06
Identities = 32/130 (24%), Positives = 59/130 (45%), Gaps = 1/130 (0%)
Frame = -3
Query: 389 LSLARNQLRALPRS-VLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVL 213
L L N+ L + + + QL + S N + ++ F + ++ N L+ +
Sbjct: 530 LRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENV 589
Query: 212 PDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLH 33
+F GL + LR+N+I+ + ++F G +S+R L L N++ + + LH
Sbjct: 590 QHKMFKGLEKPQNLMLRSNRITCVGNDSFIGLSSVRMLSLYDNQITTVAPGAF---DTLH 646
Query: 32 KLQTLTLAWN 3
L TL L N
Sbjct: 647 SLSTLNLLAN 656
Score = 42.7 bits (96), Expect = 0.001
Identities = 30/97 (30%), Positives = 43/97 (44%), Gaps = 1/97 (1%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFI 411
N F + E+ H+ I +SNN TL FSN+ L TL L + +R + P F
Sbjct: 756 NQFTLVPKEL-SNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFD 814
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYN 300
LR LSL N + +P + L+ L + N
Sbjct: 815 GLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGAN 851
Score = 41.9 bits (94), Expect = 0.002
Identities = 33/122 (27%), Positives = 55/122 (45%), Gaps = 1/122 (0%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-F 414
+N+ + + F ++ I +SNN L F L +L +L L + I ELP+ F
Sbjct: 309 QNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLF 368
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
L+ L L N++ L + L L+L N + +A F+ LRA++T +
Sbjct: 369 EGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLA 428
Query: 233 GN 228
N
Sbjct: 429 QN 430
Score = 38.7 bits (86), Expect = 0.016
Identities = 28/122 (22%), Positives = 53/122 (43%), Gaps = 2/122 (1%)
Frame = -3
Query: 587 NSFRYLDSE-IFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-F 414
N F L++ IF+ L +++I SNN ++E F + + L + + + + F
Sbjct: 535 NEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMF 594
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
+ L L N++ + G + + L+L N + +AP F L +L T +
Sbjct: 595 KGLEKPQNLMLRSNRITCVGNDSFIGLSSVRMLSLYDNQITTVAPGAFDTLHSLSTLNLL 654
Query: 233 GN 228
N
Sbjct: 655 AN 656
Score = 36.7 bits (81), Expect = 0.063
Identities = 46/197 (23%), Positives = 84/197 (42%), Gaps = 10/197 (5%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI-----RELP 423
N ++ FR L ++ + ++NN L A F+++P LRT +L +++
Sbjct: 161 NQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNLYCDCHLAWL 220
Query: 422 EEFISNSP---LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRAL 252
+++ P L T + + LR + ++ + + S S+ A + A
Sbjct: 221 SDWLRQRPRVGLYTQCMGPSHLRGHNVAEVQKREFVCSGHQSFMAPSCSVLHCPAACTCS 280
Query: 251 ETFV-MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLA 75
V G L +P +L +T + L N I VI F +R +DLS N+++
Sbjct: 281 NNIVDCRGKGLTEIPTNL---PETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQIS 337
Query: 74 -FAPDSLYSPLNQLHKL 27
APD+ + L L+ L
Sbjct: 338 ELAPDA-FQGLRSLNSL 353
>AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein.
Length = 1529
Score = 79.4 bits (187), Expect = 9e-15
Identities = 47/141 (33%), Positives = 76/141 (53%), Gaps = 2/141 (1%)
Frame = -3
Query: 419 EFISNSP--LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALET 246
E +N P + + L +N ++ +P +L + LS N ++ELAP+ F LR+L +
Sbjct: 293 EIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNS 352
Query: 245 FVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAP 66
V+ GN++ LP SLF GL +L + L NKI+ + ++ FQ ++ L L N+L
Sbjct: 353 LVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIA 412
Query: 65 DSLYSPLNQLHKLQTLTLAWN 3
+SP L +QT+ LA N
Sbjct: 413 KGTFSP---LRAIQTMHLAQN 430
Score = 69.3 bits (162), Expect = 1e-11
Identities = 40/138 (28%), Positives = 64/138 (46%)
Frame = -3
Query: 440 SIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADL 261
++R +P N+ L L N + + ++ G L L L N ++ + F DL
Sbjct: 45 ALRSVPRNIPRNT--ERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDL 102
Query: 260 RALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNR 81
+ LE ++ N LQ+ P+ LF G L + L N+I I F+GA I+ L L YN+
Sbjct: 103 KELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQ 162
Query: 80 LAFAPDSLYSPLNQLHKL 27
++ D + L L L
Sbjct: 163 ISCIEDGAFRALRDLEVL 180
Score = 64.9 bits (151), Expect = 2e-10
Identities = 42/154 (27%), Positives = 71/154 (46%), Gaps = 1/154 (0%)
Frame = -3
Query: 536 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRA 360
+ + ++ N + + F+ L LR LQL + I + F L L L RN L+
Sbjct: 58 ERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQL 117
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
P + G +L L LS N + + + F ++ +D N++ + D F LR+L
Sbjct: 118 FPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDL 177
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
++L NN I+ +S+ +F +RT L N L
Sbjct: 178 EVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 57.6 bits (133), Expect = 3e-08
Identities = 34/130 (26%), Positives = 62/130 (47%), Gaps = 1/130 (0%)
Frame = -3
Query: 389 LSLARNQLRALPRS-VLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVL 213
L L N+ L + + + QL + S N + ++ F + ++ N L+ +
Sbjct: 538 LRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENV 597
Query: 212 PDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLH 33
+F GL +L T+ LR+N+I+ + ++F G +S+R L L N++ + + LH
Sbjct: 598 QHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAF---DTLH 654
Query: 32 KLQTLTLAWN 3
L TL L N
Sbjct: 655 SLSTLNLLAN 664
Score = 56.4 bits (130), Expect = 7e-08
Identities = 29/103 (28%), Positives = 53/103 (51%)
Frame = -3
Query: 458 LQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAP 279
L LD + +P+E + L + L+ N++ L TQL +L LSYN + + P
Sbjct: 759 LYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPP 818
Query: 278 ELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKI 150
F L++L + GN++ V+P+ F+ L L+ +++ N +
Sbjct: 819 RTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPL 861
Score = 56.4 bits (130), Expect = 7e-08
Identities = 32/104 (30%), Positives = 54/104 (51%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
L L NQ +P+ L LT + LS N ++ L+ + F+++ L T ++ N L+ +P
Sbjct: 759 LYLDGNQFTLVPKE-LSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIP 817
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
F GL++L +SL N ISV+ F +++ L + N L
Sbjct: 818 PRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPL 861
Score = 55.2 bits (127), Expect = 2e-07
Identities = 29/78 (37%), Positives = 42/78 (53%)
Frame = -3
Query: 260 RALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNR 81
R + +DGN+ ++P L S ++LT + L NN+IS +S +F T + TL LSYNR
Sbjct: 754 RDVTELYLDGNQFTLVPKEL-SNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNR 812
Query: 80 LAFAPDSLYSPLNQLHKL 27
L P + L L L
Sbjct: 813 LRCIPPRTFDGLKSLRLL 830
Score = 43.6 bits (98), Expect = 5e-04
Identities = 30/122 (24%), Positives = 55/122 (45%), Gaps = 2/122 (1%)
Frame = -3
Query: 587 NSFRYLDSE-IFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-F 414
N F L++ IF+ L +++I SNN ++E F + + L + + + + F
Sbjct: 543 NEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMF 602
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
L+TL L N++ + G + + L+L N + +AP F L +L T +
Sbjct: 603 KGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLL 662
Query: 233 GN 228
N
Sbjct: 663 AN 664
Score = 42.7 bits (96), Expect = 0.001
Identities = 30/97 (30%), Positives = 43/97 (44%), Gaps = 1/97 (1%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFI 411
N F + E+ H+ I +SNN TL FSN+ L TL L + +R + P F
Sbjct: 764 NQFTLVPKEL-SNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFD 822
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYN 300
LR LSL N + +P + L+ L + N
Sbjct: 823 GLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGAN 859
Score = 41.9 bits (94), Expect = 0.002
Identities = 33/122 (27%), Positives = 55/122 (45%), Gaps = 1/122 (0%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-F 414
+N+ + + F ++ I +SNN L F L +L +L L + I ELP+ F
Sbjct: 309 QNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLF 368
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
L+ L L N++ L + L L+L N + +A F+ LRA++T +
Sbjct: 369 EGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLA 428
Query: 233 GN 228
N
Sbjct: 429 QN 430
Score = 36.7 bits (81), Expect = 0.063
Identities = 46/197 (23%), Positives = 84/197 (42%), Gaps = 10/197 (5%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI-----RELP 423
N ++ FR L ++ + ++NN L A F+++P LRT +L +++
Sbjct: 161 NQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNLYCDCHLAWL 220
Query: 422 EEFISNSP---LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRAL 252
+++ P L T + + LR + ++ + + S S+ A + A
Sbjct: 221 SDWLRQRPRVGLYTQCMGPSHLRGHNVAEVQKREFVCSGHQSFMAPSCSVLHCPAACTCS 280
Query: 251 ETFV-MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLA 75
V G L +P +L +T + L N I VI F +R +DLS N+++
Sbjct: 281 NNIVDCRGKGLTEIPTNL---PETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQIS 337
Query: 74 -FAPDSLYSPLNQLHKL 27
APD+ + L L+ L
Sbjct: 338 ELAPDA-FQGLRSLNSL 353
>Z93015-1|CAI42364.1| 481|Homo sapiens nyctalopin protein.
Length = 481
Score = 78.6 bits (185), Expect = 2e-14
Identities = 51/181 (28%), Positives = 84/181 (46%)
Frame = -3
Query: 578 RYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP 399
RYL + F L ++ + ++ ++ E + + LPALR L + R +P +
Sbjct: 124 RYLHARTFAALSRLRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVPGALRGLAN 183
Query: 398 LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 219
L L R ++ A+ S L+G +L SL+L N V + F D LE +++ N L
Sbjct: 184 LTHAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLA 243
Query: 218 VLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQ 39
LP F GLR L T++L N + ++ F + L L N +AF + + L+
Sbjct: 244 ELPADAFRGLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAFVEEGAFQNLSG 303
Query: 38 L 36
L
Sbjct: 304 L 304
Score = 69.3 bits (162), Expect = 1e-11
Identities = 49/193 (25%), Positives = 88/193 (45%), Gaps = 2/193 (1%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEA-VFSNLPALRTLQLDLSSIRELP 423
++ N+ ++ F+GL + E+++++N L A F+ L LR L L + +P
Sbjct: 92 SLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYLHARTFAALSRLRRLDLAACRLFSVP 151
Query: 422 EEFISNSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALET 246
E ++ P LR L+ N R +P LRG LT L + +A LR L +
Sbjct: 152 ERLLAELPALRELAAFDNLFRRVP-GALRGLANLTHAHLERGRIEAVASSSLQGLRRLRS 210
Query: 245 FVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAP 66
+ N ++ + F L + L +N ++ + + F+G +RTL+L N L
Sbjct: 211 LSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAFRGLRRLRTLNLGGNALDRVA 270
Query: 65 DSLYSPLNQLHKL 27
+ ++ L +L L
Sbjct: 271 RAWFADLAELELL 283
Score = 57.2 bits (132), Expect = 4e-08
Identities = 36/107 (33%), Positives = 53/107 (49%)
Frame = -3
Query: 398 LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 219
LR+LSL N++RA+ L L L+ N +AEL + F LR L T + GN L
Sbjct: 208 LRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAFRGLRRLRTLNLGGNALD 267
Query: 218 VLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
+ + F+ L L + L N I+ + FQ + + L L+ NRL
Sbjct: 268 RVARAWFADLAELELLYLDRNSIAFVEEGAFQNLSGLLALHLNGNRL 314
Score = 37.9 bits (84), Expect = 0.027
Identities = 22/72 (30%), Positives = 40/72 (55%), Gaps = 1/72 (1%)
Frame = -3
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN-RLAFAPD 63
+D N L+ L + F L +L +SLR+N +S I+ F+G + L L++N L +
Sbjct: 69 LDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYLHA 128
Query: 62 SLYSPLNQLHKL 27
++ L++L +L
Sbjct: 129 RTFAALSRLRRL 140
>BC113717-1|AAI13718.1| 581|Homo sapiens leucine rich repeat
transmembrane neuronal 3 protein.
Length = 581
Score = 78.6 bits (185), Expect = 2e-14
Identities = 56/189 (29%), Positives = 91/189 (48%), Gaps = 2/189 (1%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFI 411
N +D F G+ ++E+ +S+N F + LR L L + + L E+F
Sbjct: 95 NHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFR 154
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L +L L N LR +P + + L L L YN + LA +FA + L+ ++
Sbjct: 155 GLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEH 214
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL-AFAPDSLY 54
N+ L +LF L +L + L+ NKISVI +S++ LDLS N + AF+ S++
Sbjct: 215 NQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVF 274
Query: 53 SPLNQLHKL 27
+ L +L
Sbjct: 275 QCVPNLQRL 283
Score = 74.9 bits (176), Expect = 2e-13
Identities = 53/167 (31%), Positives = 79/167 (47%), Gaps = 1/167 (0%)
Frame = -3
Query: 500 LKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRALPRSVLRGQTQL 324
LK F L L L LD + I + E F L+ L L+ N++ + R T L
Sbjct: 76 LKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNL 135
Query: 323 TSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISV 144
+L LSYN + L E F LR L + + N L+ +P +F RNL + L N+I
Sbjct: 136 RNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRS 195
Query: 143 ISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
++ N F G ++ L L +N+ + +L+ +L LQ L L WN
Sbjct: 196 LARNVFAGMIRLKELHLEHNQFSKLNLALFP---RLVSLQNLYLQWN 239
Score = 64.5 bits (150), Expect = 3e-10
Identities = 37/115 (32%), Positives = 61/115 (53%)
Frame = -3
Query: 371 QLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSG 192
+L+ +P S+ G L+L YN++ +L F L L +D N + + ++ F+G
Sbjct: 51 KLQEIPSSISAG---CLGLSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNG 107
Query: 191 LRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+R L + L +N+IS NTF+ T++R LDLSYN+L + L +L L
Sbjct: 108 IRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSL 162
Score = 54.8 bits (126), Expect = 2e-07
Identities = 31/121 (25%), Positives = 55/121 (45%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
LSL N L+ L + +G QLT L L +N ++ + F +R L+ ++ N +
Sbjct: 66 LSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFL 125
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHK 30
++ F + NL + L N++ + F+G + +L L N L P ++ L
Sbjct: 126 NNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLEL 185
Query: 29 L 27
L
Sbjct: 186 L 186
>BC113715-1|AAI13716.1| 581|Homo sapiens leucine rich repeat
transmembrane neuronal 3 protein.
Length = 581
Score = 78.6 bits (185), Expect = 2e-14
Identities = 56/189 (29%), Positives = 91/189 (48%), Gaps = 2/189 (1%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFI 411
N +D F G+ ++E+ +S+N F + LR L L + + L E+F
Sbjct: 95 NHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFR 154
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L +L L N LR +P + + L L L YN + LA +FA + L+ ++
Sbjct: 155 GLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEH 214
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL-AFAPDSLY 54
N+ L +LF L +L + L+ NKISVI +S++ LDLS N + AF+ S++
Sbjct: 215 NQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVF 274
Query: 53 SPLNQLHKL 27
+ L +L
Sbjct: 275 QCVPNLQRL 283
Score = 74.9 bits (176), Expect = 2e-13
Identities = 53/167 (31%), Positives = 79/167 (47%), Gaps = 1/167 (0%)
Frame = -3
Query: 500 LKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRALPRSVLRGQTQL 324
LK F L L L LD + I + E F L+ L L+ N++ + R T L
Sbjct: 76 LKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNL 135
Query: 323 TSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISV 144
+L LSYN + L E F LR L + + N L+ +P +F RNL + L N+I
Sbjct: 136 RNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRS 195
Query: 143 ISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
++ N F G ++ L L +N+ + +L+ +L LQ L L WN
Sbjct: 196 LARNVFAGMIRLKELHLEHNQFSKLNLALFP---RLVSLQNLYLQWN 239
Score = 64.5 bits (150), Expect = 3e-10
Identities = 37/115 (32%), Positives = 61/115 (53%)
Frame = -3
Query: 371 QLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSG 192
+L+ +P S+ G L+L YN++ +L F L L +D N + + ++ F+G
Sbjct: 51 KLQEIPSSISAG---CLGLSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNG 107
Query: 191 LRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+R L + L +N+IS NTF+ T++R LDLSYN+L + L +L L
Sbjct: 108 IRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSL 162
Score = 54.8 bits (126), Expect = 2e-07
Identities = 31/121 (25%), Positives = 55/121 (45%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
LSL N L+ L + +G QLT L L +N ++ + F +R L+ ++ N +
Sbjct: 66 LSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFL 125
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHK 30
++ F + NL + L N++ + F+G + +L L N L P ++ L
Sbjct: 126 NNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLEL 185
Query: 29 L 27
L
Sbjct: 186 L 186
>BC112242-1|AAI12243.1| 481|Homo sapiens nyctalopin protein.
Length = 481
Score = 78.6 bits (185), Expect = 2e-14
Identities = 51/181 (28%), Positives = 84/181 (46%)
Frame = -3
Query: 578 RYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP 399
RYL + F L ++ + ++ ++ E + + LPALR L + R +P +
Sbjct: 124 RYLHARTFAALSRLRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVPGALRGLAN 183
Query: 398 LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 219
L L R ++ A+ S L+G +L SL+L N V + F D LE +++ N L
Sbjct: 184 LTHAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLA 243
Query: 218 VLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQ 39
LP F GLR L T++L N + ++ F + L L N +AF + + L+
Sbjct: 244 ELPADAFRGLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAFVEEGAFQNLSG 303
Query: 38 L 36
L
Sbjct: 304 L 304
Score = 69.3 bits (162), Expect = 1e-11
Identities = 49/193 (25%), Positives = 88/193 (45%), Gaps = 2/193 (1%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEA-VFSNLPALRTLQLDLSSIRELP 423
++ N+ ++ F+GL + E+++++N L A F+ L LR L L + +P
Sbjct: 92 SLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYLHARTFAALSRLRRLDLAACRLFSVP 151
Query: 422 EEFISNSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALET 246
E ++ P LR L+ N R +P LRG LT L + +A LR L +
Sbjct: 152 ERLLAELPALRELAAFDNLFRRVP-GALRGLANLTHAHLERGRIEAVASSSLQGLRRLRS 210
Query: 245 FVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAP 66
+ N ++ + F L + L +N ++ + + F+G +RTL+L N L
Sbjct: 211 LSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAFRGLRRLRTLNLGGNALDRVA 270
Query: 65 DSLYSPLNQLHKL 27
+ ++ L +L L
Sbjct: 271 RAWFADLAELELL 283
Score = 57.2 bits (132), Expect = 4e-08
Identities = 36/107 (33%), Positives = 53/107 (49%)
Frame = -3
Query: 398 LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 219
LR+LSL N++RA+ L L L+ N +AEL + F LR L T + GN L
Sbjct: 208 LRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAFRGLRRLRTLNLGGNALD 267
Query: 218 VLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
+ + F+ L L + L N I+ + FQ + + L L+ NRL
Sbjct: 268 RVARAWFADLAELELLYLDRNSIAFVEEGAFQNLSGLLALHLNGNRL 314
Score = 37.9 bits (84), Expect = 0.027
Identities = 22/72 (30%), Positives = 40/72 (55%), Gaps = 1/72 (1%)
Frame = -3
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN-RLAFAPD 63
+D N L+ L + F L +L +SLR+N +S I+ F+G + L L++N L +
Sbjct: 69 LDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYLHA 128
Query: 62 SLYSPLNQLHKL 27
++ L++L +L
Sbjct: 129 RTFAALSRLRRL 140
>BC111745-1|AAI11746.1| 653|Homo sapiens leucine rich repeat
containing 4 protein.
Length = 653
Score = 78.6 bits (185), Expect = 2e-14
Identities = 56/198 (28%), Positives = 88/198 (44%), Gaps = 2/198 (1%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFI 411
RNS R ++ F GL + +++ +N + F L LR L L + I +P
Sbjct: 108 RNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAF 167
Query: 410 SNSP-LRTLSLAR-NQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVM 237
+ P L L L +L + G L L L + ++ P L L LE M
Sbjct: 168 NRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYLNLGMCNIKDM-PNL-TPLVGLEELEM 225
Query: 236 DGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
GN + F GL +L + + N+++S+I N F G S+ L+L++N L+ P L
Sbjct: 226 SGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDL 285
Query: 56 YSPLNQLHKLQTLTLAWN 3
++PL L +L WN
Sbjct: 286 FTPLRYLVELHLHHNPWN 303
Score = 52.8 bits (121), Expect = 9e-07
Identities = 39/138 (28%), Positives = 60/138 (43%), Gaps = 1/138 (0%)
Frame = -3
Query: 437 IRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 258
+ E+P+ SN+ R L+L N ++ + R L L L N++ ++ F L
Sbjct: 66 LSEVPQGIPSNT--RYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLA 123
Query: 257 ALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDL-SYNR 81
+L T + N L V+P F L L + LRNN I I F S+ LDL +
Sbjct: 124 SLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKK 183
Query: 80 LAFAPDSLYSPLNQLHKL 27
L + + + L L L
Sbjct: 184 LEYISEGAFEGLFNLKYL 201
>BC111561-1|AAI11562.1| 653|Homo sapiens leucine rich repeat
containing 4 protein.
Length = 653
Score = 78.6 bits (185), Expect = 2e-14
Identities = 56/198 (28%), Positives = 88/198 (44%), Gaps = 2/198 (1%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFI 411
RNS R ++ F GL + +++ +N + F L LR L L + I +P
Sbjct: 108 RNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAF 167
Query: 410 SNSP-LRTLSLAR-NQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVM 237
+ P L L L +L + G L L L + ++ P L L LE M
Sbjct: 168 NRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYLNLGMCNIKDM-PNL-TPLVGLEELEM 225
Query: 236 DGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
GN + F GL +L + + N+++S+I N F G S+ L+L++N L+ P L
Sbjct: 226 SGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDL 285
Query: 56 YSPLNQLHKLQTLTLAWN 3
++PL L +L WN
Sbjct: 286 FTPLRYLVELHLHHNPWN 303
Score = 52.8 bits (121), Expect = 9e-07
Identities = 39/138 (28%), Positives = 60/138 (43%), Gaps = 1/138 (0%)
Frame = -3
Query: 437 IRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 258
+ E+P+ SN+ R L+L N ++ + R L L L N++ ++ F L
Sbjct: 66 LSEVPQGIPSNT--RYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLA 123
Query: 257 ALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDL-SYNR 81
+L T + N L V+P F L L + LRNN I I F S+ LDL +
Sbjct: 124 SLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKK 183
Query: 80 LAFAPDSLYSPLNQLHKL 27
L + + + L L L
Sbjct: 184 LEYISEGAFEGLFNLKYL 201
>BC111492-1|AAI11493.1| 581|Homo sapiens leucine rich repeat
transmembrane neuronal 3 protein.
Length = 581
Score = 78.6 bits (185), Expect = 2e-14
Identities = 56/189 (29%), Positives = 91/189 (48%), Gaps = 2/189 (1%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFI 411
N +D F G+ ++E+ +S+N F + LR L L + + L E+F
Sbjct: 95 NHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFR 154
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L +L L N LR +P + + L L L YN + LA +FA + L+ ++
Sbjct: 155 GLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEH 214
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL-AFAPDSLY 54
N+ L +LF L +L + L+ NKISVI +S++ LDLS N + AF+ S++
Sbjct: 215 NQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVF 274
Query: 53 SPLNQLHKL 27
+ L +L
Sbjct: 275 QCVPNLQRL 283
Score = 74.9 bits (176), Expect = 2e-13
Identities = 53/167 (31%), Positives = 79/167 (47%), Gaps = 1/167 (0%)
Frame = -3
Query: 500 LKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRALPRSVLRGQTQL 324
LK F L L L LD + I + E F L+ L L+ N++ + R T L
Sbjct: 76 LKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNL 135
Query: 323 TSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISV 144
+L LSYN + L E F LR L + + N L+ +P +F RNL + L N+I
Sbjct: 136 RNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRS 195
Query: 143 ISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
++ N F G ++ L L +N+ + +L+ +L LQ L L WN
Sbjct: 196 LARNVFAGMIRLKELHLEHNQFSKLNLALFP---RLVSLQNLYLQWN 239
Score = 64.5 bits (150), Expect = 3e-10
Identities = 37/115 (32%), Positives = 61/115 (53%)
Frame = -3
Query: 371 QLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSG 192
+L+ +P S+ G L+L YN++ +L F L L +D N + + ++ F+G
Sbjct: 51 KLQEIPSSISAG---CLGLSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNG 107
Query: 191 LRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+R L + L +N+IS NTF+ T++R LDLSYN+L + L +L L
Sbjct: 108 IRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSL 162
Score = 54.8 bits (126), Expect = 2e-07
Identities = 31/121 (25%), Positives = 55/121 (45%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
LSL N L+ L + +G QLT L L +N ++ + F +R L+ ++ N +
Sbjct: 66 LSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFL 125
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHK 30
++ F + NL + L N++ + F+G + +L L N L P ++ L
Sbjct: 126 NNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLEL 185
Query: 29 L 27
L
Sbjct: 186 L 186
>AY358315-1|AAQ88681.1| 513|Homo sapiens GFNV803 protein.
Length = 513
Score = 78.6 bits (185), Expect = 2e-14
Identities = 56/189 (29%), Positives = 91/189 (48%), Gaps = 2/189 (1%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFI 411
N +D F G+ ++E+ +S+N F + LR L L + + L E+F
Sbjct: 95 NHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFR 154
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L +L L N LR +P + + L L L YN + LA +FA + L+ ++
Sbjct: 155 GLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEH 214
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL-AFAPDSLY 54
N+ L +LF L +L + L+ NKISVI +S++ LDLS N + AF+ S++
Sbjct: 215 NQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVF 274
Query: 53 SPLNQLHKL 27
+ L +L
Sbjct: 275 QCVPNLQRL 283
Score = 74.9 bits (176), Expect = 2e-13
Identities = 53/167 (31%), Positives = 79/167 (47%), Gaps = 1/167 (0%)
Frame = -3
Query: 500 LKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRALPRSVLRGQTQL 324
LK F L L L LD + I + E F L+ L L+ N++ + R T L
Sbjct: 76 LKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNL 135
Query: 323 TSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISV 144
+L LSYN + L E F LR L + + N L+ +P +F RNL + L N+I
Sbjct: 136 RNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRS 195
Query: 143 ISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
++ N F G ++ L L +N+ + +L+ +L LQ L L WN
Sbjct: 196 LARNVFAGMIRLKELHLEHNQFSKLNLALFP---RLVSLQNLYLQWN 239
Score = 64.5 bits (150), Expect = 3e-10
Identities = 37/115 (32%), Positives = 61/115 (53%)
Frame = -3
Query: 371 QLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSG 192
+L+ +P S+ G L+L YN++ +L F L L +D N + + ++ F+G
Sbjct: 51 KLQEIPSSISAG---CLGLSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNG 107
Query: 191 LRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+R L + L +N+IS NTF+ T++R LDLSYN+L + L +L L
Sbjct: 108 IRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSL 162
Score = 54.8 bits (126), Expect = 2e-07
Identities = 31/121 (25%), Positives = 55/121 (45%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
LSL N L+ L + +G QLT L L +N ++ + F +R L+ ++ N +
Sbjct: 66 LSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFL 125
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHK 30
++ F + NL + L N++ + F+G + +L L N L P ++ L
Sbjct: 126 NNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLEL 185
Query: 29 L 27
L
Sbjct: 186 L 186
>AY358307-1|AAQ88674.1| 653|Homo sapiens NAG14 protein.
Length = 653
Score = 78.6 bits (185), Expect = 2e-14
Identities = 56/198 (28%), Positives = 88/198 (44%), Gaps = 2/198 (1%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFI 411
RNS R ++ F GL + +++ +N + F L LR L L + I +P
Sbjct: 108 RNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAF 167
Query: 410 SNSP-LRTLSLAR-NQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVM 237
+ P L L L +L + G L L L + ++ P L L LE M
Sbjct: 168 NRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYLNLGMCNIKDM-PNL-TPLVGLEELEM 225
Query: 236 DGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
GN + F GL +L + + N+++S+I N F G S+ L+L++N L+ P L
Sbjct: 226 SGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDL 285
Query: 56 YSPLNQLHKLQTLTLAWN 3
++PL L +L WN
Sbjct: 286 FTPLRYLVELHLHHNPWN 303
Score = 52.8 bits (121), Expect = 9e-07
Identities = 39/138 (28%), Positives = 60/138 (43%), Gaps = 1/138 (0%)
Frame = -3
Query: 437 IRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 258
+ E+P+ SN+ R L+L N ++ + R L L L N++ ++ F L
Sbjct: 66 LSEVPQGIPSNT--RYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLA 123
Query: 257 ALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDL-SYNR 81
+L T + N L V+P F L L + LRNN I I F S+ LDL +
Sbjct: 124 SLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKK 183
Query: 80 LAFAPDSLYSPLNQLHKL 27
L + + + L L L
Sbjct: 184 LEYISEGAFEGLFNLKYL 201
>AY182028-1|AAO67549.1| 513|Homo sapiens leucine-rich repeat
transmembrane neuronal 3 protein protein.
Length = 513
Score = 78.6 bits (185), Expect = 2e-14
Identities = 56/189 (29%), Positives = 91/189 (48%), Gaps = 2/189 (1%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFI 411
N +D F G+ ++E+ +S+N F + LR L L + + L E+F
Sbjct: 95 NHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFR 154
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L +L L N LR +P + + L L L YN + LA +FA + L+ ++
Sbjct: 155 GLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEH 214
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL-AFAPDSLY 54
N+ L +LF L +L + L+ NKISVI +S++ LDLS N + AF+ S++
Sbjct: 215 NQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVF 274
Query: 53 SPLNQLHKL 27
+ L +L
Sbjct: 275 QCVPNLQRL 283
Score = 74.9 bits (176), Expect = 2e-13
Identities = 53/167 (31%), Positives = 79/167 (47%), Gaps = 1/167 (0%)
Frame = -3
Query: 500 LKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRALPRSVLRGQTQL 324
LK F L L L LD + I + E F L+ L L+ N++ + R T L
Sbjct: 76 LKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNL 135
Query: 323 TSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISV 144
+L LSYN + L E F LR L + + N L+ +P +F RNL + L N+I
Sbjct: 136 RNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRS 195
Query: 143 ISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
++ N F G ++ L L +N+ + +L+ +L LQ L L WN
Sbjct: 196 LARNVFAGMIRLKELHLEHNQFSKLNLALFP---RLVSLQNLYLQWN 239
Score = 64.5 bits (150), Expect = 3e-10
Identities = 37/115 (32%), Positives = 61/115 (53%)
Frame = -3
Query: 371 QLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSG 192
+L+ +P S+ G L+L YN++ +L F L L +D N + + ++ F+G
Sbjct: 51 KLQEIPSSISAG---CLGLSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNG 107
Query: 191 LRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+R L + L +N+IS NTF+ T++R LDLSYN+L + L +L L
Sbjct: 108 IRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSL 162
Score = 54.8 bits (126), Expect = 2e-07
Identities = 31/121 (25%), Positives = 55/121 (45%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
LSL N L+ L + +G QLT L L +N ++ + F +R L+ ++ N +
Sbjct: 66 LSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFL 125
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHK 30
++ F + NL + L N++ + F+G + +L L N L P ++ L
Sbjct: 126 NNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLEL 185
Query: 29 L 27
L
Sbjct: 186 L 186
>AJ278865-1|CAC19014.1| 481|Homo sapiens leucine-rich repeat
protein protein.
Length = 481
Score = 78.6 bits (185), Expect = 2e-14
Identities = 51/181 (28%), Positives = 84/181 (46%)
Frame = -3
Query: 578 RYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP 399
RYL + F L ++ + ++ ++ E + + LPALR L + R +P +
Sbjct: 124 RYLHARTFAALSRLRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVPGALRGLAN 183
Query: 398 LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 219
L L R ++ A+ S L+G +L SL+L N V + F D LE +++ N L
Sbjct: 184 LTHAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLA 243
Query: 218 VLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQ 39
LP F GLR L T++L N + ++ F + L L N +AF + + L+
Sbjct: 244 ELPADAFRGLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAFVEEGAFQNLSG 303
Query: 38 L 36
L
Sbjct: 304 L 304
Score = 69.3 bits (162), Expect = 1e-11
Identities = 49/193 (25%), Positives = 88/193 (45%), Gaps = 2/193 (1%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEA-VFSNLPALRTLQLDLSSIRELP 423
++ N+ ++ F+GL + E+++++N L A F+ L LR L L + +P
Sbjct: 92 SLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYLHARTFAALSRLRRLDLAACRLFSVP 151
Query: 422 EEFISNSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALET 246
E ++ P LR L+ N R +P LRG LT L + +A LR L +
Sbjct: 152 ERLLAELPALRELAAFDNLFRRVP-GALRGLANLTHAHLERGRIEAVASSSLQGLRRLRS 210
Query: 245 FVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAP 66
+ N ++ + F L + L +N ++ + + F+G +RTL+L N L
Sbjct: 211 LSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAFRGLRRLRTLNLGGNALDRVA 270
Query: 65 DSLYSPLNQLHKL 27
+ ++ L +L L
Sbjct: 271 RAWFADLAELELL 283
Score = 57.2 bits (132), Expect = 4e-08
Identities = 36/107 (33%), Positives = 53/107 (49%)
Frame = -3
Query: 398 LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 219
LR+LSL N++RA+ L L L+ N +AEL + F LR L T + GN L
Sbjct: 208 LRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAFRGLRRLRTLNLGGNALD 267
Query: 218 VLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
+ + F+ L L + L N I+ + FQ + + L L+ NRL
Sbjct: 268 RVARAWFADLAELELLYLDRNSIAFVEEGAFQNLSGLLALHLNGNRL 314
Score = 37.9 bits (84), Expect = 0.027
Identities = 22/72 (30%), Positives = 40/72 (55%), Gaps = 1/72 (1%)
Frame = -3
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN-RLAFAPD 63
+D N L+ L + F L +L +SLR+N +S I+ F+G + L L++N L +
Sbjct: 69 LDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYLHA 128
Query: 62 SLYSPLNQLHKL 27
++ L++L +L
Sbjct: 129 RTFAALSRLRRL 140
>AF254868-1|AAG42685.1| 481|Homo sapiens nyctalopin protein.
Length = 481
Score = 78.6 bits (185), Expect = 2e-14
Identities = 51/181 (28%), Positives = 84/181 (46%)
Frame = -3
Query: 578 RYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP 399
RYL + F L ++ + ++ ++ E + + LPALR L + R +P +
Sbjct: 124 RYLHARTFAALSRLRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVPGALRGLAN 183
Query: 398 LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 219
L L R ++ A+ S L+G +L SL+L N V + F D LE +++ N L
Sbjct: 184 LTHAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLA 243
Query: 218 VLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQ 39
LP F GLR L T++L N + ++ F + L L N +AF + + L+
Sbjct: 244 ELPADAFRGLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAFVEEGAFQNLSG 303
Query: 38 L 36
L
Sbjct: 304 L 304
Score = 69.3 bits (162), Expect = 1e-11
Identities = 49/193 (25%), Positives = 88/193 (45%), Gaps = 2/193 (1%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEA-VFSNLPALRTLQLDLSSIRELP 423
++ N+ ++ F+GL + E+++++N L A F+ L LR L L + +P
Sbjct: 92 SLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYLHARTFAALSRLRRLDLAACRLFSVP 151
Query: 422 EEFISNSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALET 246
E ++ P LR L+ N R +P LRG LT L + +A LR L +
Sbjct: 152 ERLLAELPALRELAAFDNLFRRVP-GALRGLANLTHAHLERGRIEAVASSSLQGLRRLRS 210
Query: 245 FVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAP 66
+ N ++ + F L + L +N ++ + + F+G +RTL+L N L
Sbjct: 211 LSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAFRGLRRLRTLNLGGNALDRVA 270
Query: 65 DSLYSPLNQLHKL 27
+ ++ L +L L
Sbjct: 271 RAWFADLAELELL 283
Score = 57.2 bits (132), Expect = 4e-08
Identities = 36/107 (33%), Positives = 53/107 (49%)
Frame = -3
Query: 398 LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 219
LR+LSL N++RA+ L L L+ N +AEL + F LR L T + GN L
Sbjct: 208 LRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAFRGLRRLRTLNLGGNALD 267
Query: 218 VLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
+ + F+ L L + L N I+ + FQ + + L L+ NRL
Sbjct: 268 RVARAWFADLAELELLYLDRNSIAFVEEGAFQNLSGLLALHLNGNRL 314
Score = 37.9 bits (84), Expect = 0.027
Identities = 22/72 (30%), Positives = 40/72 (55%), Gaps = 1/72 (1%)
Frame = -3
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN-RLAFAPD 63
+D N L+ L + F L +L +SLR+N +S I+ F+G + L L++N L +
Sbjct: 69 LDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYLHA 128
Query: 62 SLYSPLNQLHKL 27
++ L++L +L
Sbjct: 129 RTFAALSRLRRL 140
>AF196976-1|AAG28019.2| 653|Homo sapiens brain tumor associated
protein LRRC4 protein.
Length = 653
Score = 78.6 bits (185), Expect = 2e-14
Identities = 56/198 (28%), Positives = 88/198 (44%), Gaps = 2/198 (1%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFI 411
RNS R ++ F GL + +++ +N + F L LR L L + I +P
Sbjct: 108 RNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAF 167
Query: 410 SNSP-LRTLSLAR-NQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVM 237
+ P L L L +L + G L L L + ++ P L L LE M
Sbjct: 168 NRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYLNLGMCNIKDM-PNL-TPLVGLEELEM 225
Query: 236 DGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
GN + F GL +L + + N+++S+I N F G S+ L+L++N L+ P L
Sbjct: 226 SGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDL 285
Query: 56 YSPLNQLHKLQTLTLAWN 3
++PL L +L WN
Sbjct: 286 FTPLRYLVELHLHHNPWN 303
Score = 52.8 bits (121), Expect = 9e-07
Identities = 39/138 (28%), Positives = 60/138 (43%), Gaps = 1/138 (0%)
Frame = -3
Query: 437 IRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 258
+ E+P+ SN+ R L+L N ++ + R L L L N++ ++ F L
Sbjct: 66 LSEVPQGIPSNT--RYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLA 123
Query: 257 ALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDL-SYNR 81
+L T + N L V+P F L L + LRNN I I F S+ LDL +
Sbjct: 124 SLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKK 183
Query: 80 LAFAPDSLYSPLNQLHKL 27
L + + + L L L
Sbjct: 184 LEYISEGAFEGLFNLKYL 201
>Z23091-1|CAA80637.1| 560|Homo sapiens platelet glycoprotein V
precursor protein.
Length = 560
Score = 78.2 bits (184), Expect = 2e-14
Identities = 54/187 (28%), Positives = 86/187 (45%), Gaps = 2/187 (1%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFI 411
RN R + F L ++ + +S N L A+F + L L L + + ELP
Sbjct: 227 RNHIRSIAPGAFDRLPNLSSLTLSRNHLAFLPSALFLHSHNLTLLTLFENPLAELPGVLF 286
Query: 410 SN-SPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPE-LFADLRALETFVM 237
L+ L L R QLR LP + R ++L L ++ + P+ F L L+ +
Sbjct: 287 GEMGGLQELWLNRTQLRTLPAAAFRNLSRLRYLGVTLSPRLSALPQGAFQGLGELQVLAL 346
Query: 236 DGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
N L LPD L GL L VSLR N++ + F+ +S+ ++ L +N+L P +
Sbjct: 347 HSNGLTALPDGLLRGLGKLRQVSLRRNRLRALPRALFRNLSSLESVQLDHNQLETLPGDV 406
Query: 56 YSPLNQL 36
+ L +L
Sbjct: 407 FGALPRL 413
Score = 77.4 bits (182), Expect = 4e-14
Identities = 52/150 (34%), Positives = 77/150 (51%), Gaps = 2/150 (1%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSS-IRELP 423
T+ N L +F + +QE+ ++ TL A F NL LR L + LS + LP
Sbjct: 272 TLFENPLAELPGVLFGEMGGLQELWLNRTQLRTLPAAAFRNLSRLRYLGVTLSPRLSALP 331
Query: 422 E-EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALET 246
+ F L+ L+L N L ALP +LRG +L ++L N + L LF +L +LE+
Sbjct: 332 QGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSLRRNRLRALPRALFRNLSSLES 391
Query: 245 FVMDGNELQVLPDSLFSGLRNLTTVSLRNN 156
+D N+L+ LP +F L LT V L +N
Sbjct: 392 VQLDHNQLETLPGDVFGALPRLTEVLLGHN 421
Score = 76.6 bits (180), Expect = 6e-14
Identities = 52/188 (27%), Positives = 93/188 (49%), Gaps = 1/188 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFI- 411
N+ R +D +F+ L ++QE+ ++ N L ++F+NL L+ L L +++ LP+ +
Sbjct: 132 NALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTHLPKGLLG 191
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
+ + L L L N+L +L +L LT L N + +AP F L L + +
Sbjct: 192 AQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSR 251
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N L LP +LF NLT ++L N ++ + F ++ L L+ +L P + +
Sbjct: 252 NHLAFLPSALFLHSHNLTLLTLFENPLAELPGVLFGEMGGLQELWLNRTQLRTLPAAAFR 311
Query: 50 PLNQLHKL 27
L++L L
Sbjct: 312 NLSRLRYL 319
Score = 71.7 bits (168), Expect = 2e-12
Identities = 48/160 (30%), Positives = 75/160 (46%), Gaps = 1/160 (0%)
Frame = -3
Query: 500 LKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQL 324
L+ FS + L+ L + S I + P F L+TL L+RN++ LP ++L L
Sbjct: 65 LQSQSFSGMTVLQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLL 124
Query: 323 TSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISV 144
L L +NA+ + +F L L+ ++ N+L LP SLF+ L NL + L N ++
Sbjct: 125 EQLFLDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTH 184
Query: 143 ISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
+ + L L NRL L + L L +LQ
Sbjct: 185 LPKGLLGAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQ 224
Score = 66.9 bits (156), Expect = 5e-11
Identities = 50/185 (27%), Positives = 79/185 (42%), Gaps = 2/185 (1%)
Frame = -3
Query: 572 LDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPL 396
LDS + L + E++ N ++ F LP L +L L + + LP F+ + L
Sbjct: 209 LDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSRNHLAFLPSALFLHSHNL 268
Query: 395 RTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETF-VMDGNELQ 219
L+L N L LP + L L L+ + L F +L L V L
Sbjct: 269 TLLTLFENPLAELPGVLFGEMGGLQELWLNRTQLRTLPAAAFRNLSRLRYLGVTLSPRLS 328
Query: 218 VLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQ 39
LP F GL L ++L +N ++ + +G +R + L NRL P +L+ L+
Sbjct: 329 ALPQGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSLRRNRLRALPRALFRNLSS 388
Query: 38 LHKLQ 24
L +Q
Sbjct: 389 LESVQ 393
>L11238-1|AAA03069.1| 560|Homo sapiens platelet membrane
glycoprotein V protein.
Length = 560
Score = 78.2 bits (184), Expect = 2e-14
Identities = 54/187 (28%), Positives = 86/187 (45%), Gaps = 2/187 (1%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFI 411
RN R + F L ++ + +S N L A+F + L L L + + ELP
Sbjct: 227 RNHIRSIAPGAFDRLPNLSSLTLSRNHLAFLPSALFLHSHNLTLLTLFENPLAELPGVLF 286
Query: 410 SN-SPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPE-LFADLRALETFVM 237
L+ L L R QLR LP + R ++L L ++ + P+ F L L+ +
Sbjct: 287 GEMGGLQELWLNRTQLRTLPAAAFRNLSRLRYLGVTLSPRLSALPQGAFQGLGELQVLAL 346
Query: 236 DGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
N L LPD L GL L VSLR N++ + F+ +S+ ++ L +N+L P +
Sbjct: 347 HSNGLTALPDGLLRGLGKLRQVSLRRNRLRALPRALFRNLSSLESVQLDHNQLETLPGDV 406
Query: 56 YSPLNQL 36
+ L +L
Sbjct: 407 FGALPRL 413
Score = 77.4 bits (182), Expect = 4e-14
Identities = 52/150 (34%), Positives = 77/150 (51%), Gaps = 2/150 (1%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSS-IRELP 423
T+ N L +F + +QE+ ++ TL A F NL LR L + LS + LP
Sbjct: 272 TLFENPLAELPGVLFGEMGGLQELWLNRTQLRTLPAAAFRNLSRLRYLGVTLSPRLSALP 331
Query: 422 E-EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALET 246
+ F L+ L+L N L ALP +LRG +L ++L N + L LF +L +LE+
Sbjct: 332 QGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSLRRNRLRALPRALFRNLSSLES 391
Query: 245 FVMDGNELQVLPDSLFSGLRNLTTVSLRNN 156
+D N+L+ LP +F L LT V L +N
Sbjct: 392 VQLDHNQLETLPGDVFGALPRLTEVLLGHN 421
Score = 76.6 bits (180), Expect = 6e-14
Identities = 52/188 (27%), Positives = 93/188 (49%), Gaps = 1/188 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFI- 411
N+ R +D +F+ L ++QE+ ++ N L ++F+NL L+ L L +++ LP+ +
Sbjct: 132 NALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTHLPKGLLG 191
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
+ + L L L N+L +L +L LT L N + +AP F L L + +
Sbjct: 192 AQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSR 251
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N L LP +LF NLT ++L N ++ + F ++ L L+ +L P + +
Sbjct: 252 NHLAFLPSALFLHSHNLTLLTLFENPLAELPGVLFGEMGGLQELWLNRTQLRTLPAAAFR 311
Query: 50 PLNQLHKL 27
L++L L
Sbjct: 312 NLSRLRYL 319
Score = 71.7 bits (168), Expect = 2e-12
Identities = 48/160 (30%), Positives = 75/160 (46%), Gaps = 1/160 (0%)
Frame = -3
Query: 500 LKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQL 324
L+ FS + L+ L + S I + P F L+TL L+RN++ LP ++L L
Sbjct: 65 LQSQSFSGMTVLQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLL 124
Query: 323 TSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISV 144
L L +NA+ + +F L L+ ++ N+L LP SLF+ L NL + L N ++
Sbjct: 125 EQLFLDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTH 184
Query: 143 ISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
+ + L L NRL L + L L +LQ
Sbjct: 185 LPKGLLGAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQ 224
Score = 66.9 bits (156), Expect = 5e-11
Identities = 50/185 (27%), Positives = 79/185 (42%), Gaps = 2/185 (1%)
Frame = -3
Query: 572 LDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPL 396
LDS + L + E++ N ++ F LP L +L L + + LP F+ + L
Sbjct: 209 LDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSRNHLAFLPSALFLHSHNL 268
Query: 395 RTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETF-VMDGNELQ 219
L+L N L LP + L L L+ + L F +L L V L
Sbjct: 269 TLLTLFENPLAELPGVLFGEMGGLQELWLNRTQLRTLPAAAFRNLSRLRYLGVTLSPRLS 328
Query: 218 VLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQ 39
LP F GL L ++L +N ++ + +G +R + L NRL P +L+ L+
Sbjct: 329 ALPQGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSLRRNRLRALPRALFRNLSS 388
Query: 38 LHKLQ 24
L +Q
Sbjct: 389 LESVQ 393
>BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 78.2 bits (184), Expect = 2e-14
Identities = 52/197 (26%), Positives = 98/197 (49%), Gaps = 1/197 (0%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EF 414
RN + +IF+ L H+Q +++ N ++ F L +LR+L++ + I +L + F
Sbjct: 201 RNRMSMIPPKIFK-LPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAF 259
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
+ + L L N L + + L G L L +S NA+ ++P+ + + L +
Sbjct: 260 FGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLS 319
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
N+L L +S F GL L ++L +N+++ I+ F+ ++++TLDL N +++A +
Sbjct: 320 YNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDAS 379
Query: 53 SPLNQLHKLQTLTLAWN 3
L L L L N
Sbjct: 380 EAFAGLTSLTKLILQGN 396
Score = 73.7 bits (173), Expect = 4e-13
Identities = 53/186 (28%), Positives = 91/186 (48%), Gaps = 4/186 (2%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PE 420
M RN L F GL++++E+++ +N + + L L+ L + ++I + P+
Sbjct: 246 MQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPD 305
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+ L L L+ NQL L S G + L L L N V +A +F L L+T
Sbjct: 306 AWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLD 365
Query: 239 MDGNELQ-VLPDS--LFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFA 69
+ NE+ + D+ F+GL +LT + L+ N+I I+ F G S+ LDL+ N +
Sbjct: 366 LRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIMSI 425
Query: 68 PDSLYS 51
++ +S
Sbjct: 426 QENAFS 431
Score = 70.1 bits (164), Expect = 6e-12
Identities = 46/172 (26%), Positives = 84/172 (48%), Gaps = 1/172 (0%)
Frame = -3
Query: 539 IQEIKISNNVPLTLKEAVFSNLPA-LRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLR 363
++ + +SNN TL+ F NL + L ++L+ + + +P + L+ L L RN+++
Sbjct: 169 LKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFKLPHLQFLELKRNRIK 228
Query: 362 ALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRN 183
+ +G L SL + N +++L F L +E ++ N L + GLR
Sbjct: 229 IVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRM 288
Query: 182 LTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
L + + N I IS + ++ + LDLSYN+L +S + L+ L +L
Sbjct: 289 LQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERL 340
Score = 61.7 bits (143), Expect = 2e-09
Identities = 46/162 (28%), Positives = 76/162 (46%), Gaps = 4/162 (2%)
Frame = -3
Query: 551 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLAR 375
GL +Q++ +S N + + L L L + + L E F+ S L L+L
Sbjct: 285 GLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGD 344
Query: 374 NQLRALPRSVLRGQTQLTSLTLSYNAVA---ELAPELFADLRALETFVMDGNELQVLPDS 204
N++ + V R + L +L L N ++ E A E FA L +L ++ GN+++ +
Sbjct: 345 NRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKK 404
Query: 203 LFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
F GL +L + L NN I I N F T ++ L L+ + L
Sbjct: 405 AFIGLESLEHLDLNNNAIMSIQENAF-SQTHLKELILNTSSL 445
Score = 46.8 bits (106), Expect = 6e-05
Identities = 36/149 (24%), Positives = 68/149 (45%), Gaps = 1/149 (0%)
Frame = -3
Query: 467 LRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAE 288
L+ ++++ + + E+P S + LSL N + + L+ L SL LS N ++E
Sbjct: 99 LQEVKMNYNELTEIPYFGEPTSNITLLSLVHNIIPEINAQALQFYPALESLDLSSNIISE 158
Query: 287 LAPELFADLRALETFVMDGNELQVLPDSLFSGL-RNLTTVSLRNNKISVISMNTFQGATS 111
+ F ++ L+ + N + L F L +L V L N++S+I F+
Sbjct: 159 IKTSSFPRMQ-LKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFK-LPH 216
Query: 110 IRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
++ L+L NR+ + L+ L L+
Sbjct: 217 LQFLELKRNRIKIVEGLTFQGLDSLRSLK 245
>BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 78.2 bits (184), Expect = 2e-14
Identities = 52/197 (26%), Positives = 98/197 (49%), Gaps = 1/197 (0%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EF 414
RN + +IF+ L H+Q +++ N ++ F L +LR+L++ + I +L + F
Sbjct: 201 RNRMSMIPPKIFK-LPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAF 259
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
+ + L L N L + + L G L L +S NA+ ++P+ + + L +
Sbjct: 260 FGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLS 319
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
N+L L +S F GL L ++L +N+++ I+ F+ ++++TLDL N +++A +
Sbjct: 320 YNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDAS 379
Query: 53 SPLNQLHKLQTLTLAWN 3
L L L L N
Sbjct: 380 EAFAGLTSLTKLILQGN 396
Score = 73.7 bits (173), Expect = 4e-13
Identities = 53/186 (28%), Positives = 91/186 (48%), Gaps = 4/186 (2%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PE 420
M RN L F GL++++E+++ +N + + L L+ L + ++I + P+
Sbjct: 246 MQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPD 305
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+ L L L+ NQL L S G + L L L N V +A +F L L+T
Sbjct: 306 AWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLD 365
Query: 239 MDGNELQ-VLPDS--LFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFA 69
+ NE+ + D+ F+GL +LT + L+ N+I I+ F G S+ LDL+ N +
Sbjct: 366 LRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIMSI 425
Query: 68 PDSLYS 51
++ +S
Sbjct: 426 QENAFS 431
Score = 70.1 bits (164), Expect = 6e-12
Identities = 46/172 (26%), Positives = 84/172 (48%), Gaps = 1/172 (0%)
Frame = -3
Query: 539 IQEIKISNNVPLTLKEAVFSNLPA-LRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLR 363
++ + +SNN TL+ F NL + L ++L+ + + +P + L+ L L RN+++
Sbjct: 169 LKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFKLPHLQFLELKRNRIK 228
Query: 362 ALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRN 183
+ +G L SL + N +++L F L +E ++ N L + GLR
Sbjct: 229 IVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRM 288
Query: 182 LTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
L + + N I IS + ++ + LDLSYN+L +S + L+ L +L
Sbjct: 289 LQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERL 340
Score = 61.7 bits (143), Expect = 2e-09
Identities = 46/162 (28%), Positives = 76/162 (46%), Gaps = 4/162 (2%)
Frame = -3
Query: 551 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLAR 375
GL +Q++ +S N + + L L L + + L E F+ S L L+L
Sbjct: 285 GLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGD 344
Query: 374 NQLRALPRSVLRGQTQLTSLTLSYNAVA---ELAPELFADLRALETFVMDGNELQVLPDS 204
N++ + V R + L +L L N ++ E A E FA L +L ++ GN+++ +
Sbjct: 345 NRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKK 404
Query: 203 LFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
F GL +L + L NN I I N F T ++ L L+ + L
Sbjct: 405 AFIGLESLEHLDLNNNAIMSIQENAF-SQTHLKELILNTSSL 445
Score = 46.8 bits (106), Expect = 6e-05
Identities = 36/149 (24%), Positives = 68/149 (45%), Gaps = 1/149 (0%)
Frame = -3
Query: 467 LRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAE 288
L+ ++++ + + E+P S + LSL N + + L+ L SL LS N ++E
Sbjct: 99 LQEVKMNYNELTEIPYFGEPTSNITLLSLVHNIIPEINAQALQFYPALESLDLSSNIISE 158
Query: 287 LAPELFADLRALETFVMDGNELQVLPDSLFSGL-RNLTTVSLRNNKISVISMNTFQGATS 111
+ F ++ L+ + N + L F L +L V L N++S+I F+
Sbjct: 159 IKTSSFPRMQ-LKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFK-LPH 216
Query: 110 IRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
++ L+L NR+ + L+ L L+
Sbjct: 217 LQFLELKRNRIKIVEGLTFQGLDSLRSLK 245
>AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 78.2 bits (184), Expect = 2e-14
Identities = 52/197 (26%), Positives = 98/197 (49%), Gaps = 1/197 (0%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EF 414
RN + +IF+ L H+Q +++ N ++ F L +LR+L++ + I +L + F
Sbjct: 201 RNRMSMIPPKIFK-LPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAF 259
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
+ + L L N L + + L G L L +S NA+ ++P+ + + L +
Sbjct: 260 FGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLS 319
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
N+L L +S F GL L ++L +N+++ I+ F+ ++++TLDL N +++A +
Sbjct: 320 YNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDAS 379
Query: 53 SPLNQLHKLQTLTLAWN 3
L L L L N
Sbjct: 380 EAFAGLTSLTKLILQGN 396
Score = 73.7 bits (173), Expect = 4e-13
Identities = 53/186 (28%), Positives = 91/186 (48%), Gaps = 4/186 (2%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PE 420
M RN L F GL++++E+++ +N + + L L+ L + ++I + P+
Sbjct: 246 MQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPD 305
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+ L L L+ NQL L S G + L L L N V +A +F L L+T
Sbjct: 306 AWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLD 365
Query: 239 MDGNELQ-VLPDS--LFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFA 69
+ NE+ + D+ F+GL +LT + L+ N+I I+ F G S+ LDL+ N +
Sbjct: 366 LRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIMSI 425
Query: 68 PDSLYS 51
++ +S
Sbjct: 426 QENAFS 431
Score = 70.1 bits (164), Expect = 6e-12
Identities = 46/172 (26%), Positives = 84/172 (48%), Gaps = 1/172 (0%)
Frame = -3
Query: 539 IQEIKISNNVPLTLKEAVFSNLPA-LRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLR 363
++ + +SNN TL+ F NL + L ++L+ + + +P + L+ L L RN+++
Sbjct: 169 LKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFKLPHLQFLELKRNRIK 228
Query: 362 ALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRN 183
+ +G L SL + N +++L F L +E ++ N L + GLR
Sbjct: 229 IVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRM 288
Query: 182 LTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
L + + N I IS + ++ + LDLSYN+L +S + L+ L +L
Sbjct: 289 LQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERL 340
Score = 61.7 bits (143), Expect = 2e-09
Identities = 46/162 (28%), Positives = 76/162 (46%), Gaps = 4/162 (2%)
Frame = -3
Query: 551 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLAR 375
GL +Q++ +S N + + L L L + + L E F+ S L L+L
Sbjct: 285 GLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGD 344
Query: 374 NQLRALPRSVLRGQTQLTSLTLSYNAVA---ELAPELFADLRALETFVMDGNELQVLPDS 204
N++ + V R + L +L L N ++ E A E FA L +L ++ GN+++ +
Sbjct: 345 NRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKK 404
Query: 203 LFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
F GL +L + L NN I I N F T ++ L L+ + L
Sbjct: 405 AFIGLESLEHLDLNNNAIMSIQENAF-SQTHLKELILNTSSL 445
Score = 46.8 bits (106), Expect = 6e-05
Identities = 36/149 (24%), Positives = 68/149 (45%), Gaps = 1/149 (0%)
Frame = -3
Query: 467 LRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAE 288
L+ ++++ + + E+P S + LSL N + + L+ L SL LS N ++E
Sbjct: 99 LQEVKMNYNELTEIPYFGEPTSNITLLSLVHNIIPEINAQALQFYPALESLDLSSNIISE 158
Query: 287 LAPELFADLRALETFVMDGNELQVLPDSLFSGL-RNLTTVSLRNNKISVISMNTFQGATS 111
+ F ++ L+ + N + L F L +L V L N++S+I F+
Sbjct: 159 IKTSSFPRMQ-LKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFK-LPH 216
Query: 110 IRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
++ L+L NR+ + L+ L L+
Sbjct: 217 LQFLELKRNRIKIVEGLTFQGLDSLRSLK 245
>AK172751-1|BAD18737.1| 653|Homo sapiens protein ( Homo sapiens
cDNA FLJ23912 fis, clone CAE04210, highly similar to
Homo sapiens leucine rich repeat containing 4 (LRRC4).
).
Length = 653
Score = 78.2 bits (184), Expect = 2e-14
Identities = 56/198 (28%), Positives = 88/198 (44%), Gaps = 2/198 (1%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFI 411
RNS R ++ F GL + +++ +N + F L LR L L + I +P
Sbjct: 108 RNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAF 167
Query: 410 SNSP-LRTLSLAR-NQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVM 237
+ P L L L +L + G L L L + ++ P L L LE M
Sbjct: 168 NRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYLNLGMCNIKDM-PNL-TPLVGLEELEM 225
Query: 236 DGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
GN + F GL +L + + N+++S+I N F G S+ L+L++N L+ P L
Sbjct: 226 SGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDL 285
Query: 56 YSPLNQLHKLQTLTLAWN 3
++PL L +L WN
Sbjct: 286 FTPLRYLVELHLHHDPWN 303
Score = 52.8 bits (121), Expect = 9e-07
Identities = 39/138 (28%), Positives = 60/138 (43%), Gaps = 1/138 (0%)
Frame = -3
Query: 437 IRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 258
+ E+P+ SN+ R L+L N ++ + R L L L N++ ++ F L
Sbjct: 66 LSEVPQGIPSNT--RYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLA 123
Query: 257 ALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDL-SYNR 81
+L T + N L V+P F L L + LRNN I I F S+ LDL +
Sbjct: 124 SLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKK 183
Query: 80 LAFAPDSLYSPLNQLHKL 27
L + + + L L L
Sbjct: 184 LEYISEGAFEGLFNLKYL 201
>AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein.
Length = 1073
Score = 78.2 bits (184), Expect = 2e-14
Identities = 52/197 (26%), Positives = 98/197 (49%), Gaps = 1/197 (0%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EF 414
RN + +IF+ L H+Q +++ N ++ F L +LR+L++ + I +L + F
Sbjct: 209 RNRMSMIPPKIFK-LPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAF 267
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
+ + L L N L + + L G L L +S NA+ ++P+ + + L +
Sbjct: 268 FGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLS 327
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
N+L L +S F GL L ++L +N+++ I+ F+ ++++TLDL N +++A +
Sbjct: 328 YNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDAS 387
Query: 53 SPLNQLHKLQTLTLAWN 3
L L L L N
Sbjct: 388 EAFAGLTSLTKLILQGN 404
Score = 73.7 bits (173), Expect = 4e-13
Identities = 53/186 (28%), Positives = 91/186 (48%), Gaps = 4/186 (2%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PE 420
M RN L F GL++++E+++ +N + + L L+ L + ++I + P+
Sbjct: 254 MQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPD 313
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+ L L L+ NQL L S G + L L L N V +A +F L L+T
Sbjct: 314 AWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLD 373
Query: 239 MDGNELQ-VLPDS--LFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFA 69
+ NE+ + D+ F+GL +LT + L+ N+I I+ F G S+ LDL+ N +
Sbjct: 374 LRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIMSI 433
Query: 68 PDSLYS 51
++ +S
Sbjct: 434 QENAFS 439
Score = 70.1 bits (164), Expect = 6e-12
Identities = 46/172 (26%), Positives = 84/172 (48%), Gaps = 1/172 (0%)
Frame = -3
Query: 539 IQEIKISNNVPLTLKEAVFSNLPA-LRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLR 363
++ + +SNN TL+ F NL + L ++L+ + + +P + L+ L L RN+++
Sbjct: 177 LKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFKLPHLQFLELKRNRIK 236
Query: 362 ALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRN 183
+ +G L SL + N +++L F L +E ++ N L + GLR
Sbjct: 237 IVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRM 296
Query: 182 LTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
L + + N I IS + ++ + LDLSYN+L +S + L+ L +L
Sbjct: 297 LQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERL 348
Score = 61.7 bits (143), Expect = 2e-09
Identities = 46/162 (28%), Positives = 76/162 (46%), Gaps = 4/162 (2%)
Frame = -3
Query: 551 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLAR 375
GL +Q++ +S N + + L L L + + L E F+ S L L+L
Sbjct: 293 GLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGD 352
Query: 374 NQLRALPRSVLRGQTQLTSLTLSYNAVA---ELAPELFADLRALETFVMDGNELQVLPDS 204
N++ + V R + L +L L N ++ E A E FA L +L ++ GN+++ +
Sbjct: 353 NRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKK 412
Query: 203 LFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
F GL +L + L NN I I N F T ++ L L+ + L
Sbjct: 413 AFIGLESLEHLDLNNNAIMSIQENAF-SQTHLKELILNTSSL 453
Score = 46.8 bits (106), Expect = 6e-05
Identities = 36/149 (24%), Positives = 68/149 (45%), Gaps = 1/149 (0%)
Frame = -3
Query: 467 LRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAE 288
L+ ++++ + + E+P S + LSL N + + L+ L SL LS N ++E
Sbjct: 107 LQEVKMNYNELTEIPYFGEPTSNITLLSLVHNIIPEINAQALQFYPALESLDLSSNIISE 166
Query: 287 LAPELFADLRALETFVMDGNELQVLPDSLFSGL-RNLTTVSLRNNKISVISMNTFQGATS 111
+ F ++ L+ + N + L F L +L V L N++S+I F+
Sbjct: 167 IKTSSFPRMQ-LKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFK-LPH 224
Query: 110 IRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
++ L+L NR+ + L+ L L+
Sbjct: 225 LQFLELKRNRIKIVEGLTFQGLDSLRSLK 253
>BC146759-1|AAI46760.1| 1523|Homo sapiens slit homolog 3
(Drosophila) protein.
Length = 1523
Score = 77.8 bits (183), Expect = 3e-14
Identities = 41/129 (31%), Positives = 72/129 (55%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
+ L +N ++A+P +L + +S N ++++AP+ F L++L + V+ GN++ +
Sbjct: 312 IRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIA 371
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHK 30
LF GL +L + L NKI+ + +NTFQ ++ L L N+L L++P L
Sbjct: 372 KGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAP---LQS 428
Query: 29 LQTLTLAWN 3
+QTL LA N
Sbjct: 429 IQTLHLAQN 437
Score = 74.9 bits (176), Expect = 2e-13
Identities = 43/135 (31%), Positives = 75/135 (55%), Gaps = 2/135 (1%)
Frame = -3
Query: 482 SNLP-ALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTL 309
+NLP + ++L+ +SI+ +P F L+ + +++NQ+ + +G LTSL L
Sbjct: 303 ANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVL 362
Query: 308 SYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNT 129
N + E+A LF L +L+ +++ N++ L + F L+NL +SL +NK+ IS
Sbjct: 363 YGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGL 422
Query: 128 FQGATSIRTLDLSYN 84
F SI+TL L+ N
Sbjct: 423 FAPLQSIQTLHLAQN 437
Score = 70.1 bits (164), Expect = 6e-12
Identities = 45/161 (27%), Positives = 77/161 (47%), Gaps = 2/161 (1%)
Frame = -3
Query: 554 RGLD-HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSL 381
RG+ + + + + N + + F+ L LR L L+ + + + F L L L
Sbjct: 57 RGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRL 116
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSL 201
+N+L+ LP + + +LT L LS N + + + F + ++ +D N + + D
Sbjct: 117 NKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGA 176
Query: 200 FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
F LR+L ++L NN IS I + +F IRTL L N L
Sbjct: 177 FRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 217
Score = 67.3 bits (157), Expect = 4e-11
Identities = 42/137 (30%), Positives = 63/137 (45%)
Frame = -3
Query: 437 IRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 258
+R +P N+ L L RN + + + G L L L N V+ + F DL+
Sbjct: 52 LRAVPRGIPRNA--ERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLK 109
Query: 257 ALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
LE ++ N+LQVLP+ LF LT + L N+I I F+G T ++ L L N +
Sbjct: 110 QLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHI 169
Query: 77 AFAPDSLYSPLNQLHKL 27
+ D + L L L
Sbjct: 170 SCIEDGAFRALRDLEIL 186
Score = 61.7 bits (143), Expect = 2e-09
Identities = 36/130 (27%), Positives = 65/130 (50%), Gaps = 1/130 (0%)
Frame = -3
Query: 389 LSLARNQLRALPRS-VLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVL 213
L L N++ L + + + L + LS N + E+ F +++ ++ GN+L+ +
Sbjct: 537 LRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETV 596
Query: 212 PDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLH 33
+F GL L T+ LR+N I +S +TF G +S+R L L NR+ ++ L L
Sbjct: 597 HGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLS 656
Query: 32 KLQTLTLAWN 3
+ L+ +N
Sbjct: 657 TINLLSNPFN 666
Score = 55.2 bits (127), Expect = 2e-07
Identities = 33/79 (41%), Positives = 45/79 (56%)
Frame = -3
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
++GN L +P L S LR+LT + L NN IS+++ TF + + TL LSYNRL P
Sbjct: 759 LEGNHLTAVPREL-SALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVH 817
Query: 59 LYSPLNQLHKLQTLTLAWN 3
+ N L L+ LTL N
Sbjct: 818 AF---NGLRSLRVLTLHGN 833
Score = 54.0 bits (124), Expect = 4e-07
Identities = 32/115 (27%), Positives = 53/115 (46%)
Frame = -3
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
LRA+PR + R +L L N + + FA L+ L ++ N++ V+ F L
Sbjct: 52 LRAVPRGIPRNAERLD---LDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDL 108
Query: 188 RNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
+ L + L NK+ V+ FQ + LDLS N++ P + + + LQ
Sbjct: 109 KQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQ 163
Score = 50.8 bits (116), Expect = 4e-06
Identities = 26/105 (24%), Positives = 55/105 (52%)
Frame = -3
Query: 398 LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 219
LR ++L+ N+++ + G + L L+ N + + +F L L+T ++ N +
Sbjct: 559 LRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIG 618
Query: 218 VLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
+ + F+GL ++ +SL +N+I+ I+ F S+ T++L N
Sbjct: 619 CVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSN 663
Score = 50.0 bits (114), Expect = 6e-06
Identities = 26/103 (25%), Positives = 51/103 (49%)
Frame = -3
Query: 458 LQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAP 279
L L+ + + +P E + L + L+ N + L + L++L LSYN + +
Sbjct: 757 LYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPV 816
Query: 278 ELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKI 150
F LR+L + GN++ +P+ F+ L +L+ ++L N +
Sbjct: 817 HAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPL 859
Score = 45.6 bits (103), Expect = 1e-04
Identities = 24/100 (24%), Positives = 49/100 (49%)
Frame = -3
Query: 326 LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKIS 147
+ + L N++ + F + L+ + N++ + F GL++LT++ L NKI+
Sbjct: 309 IVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKIT 368
Query: 146 VISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
I+ F G S++ L L+ N++ + + L L+ L
Sbjct: 369 EIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLL 408
Score = 42.3 bits (95), Expect = 0.001
Identities = 28/112 (25%), Positives = 52/112 (46%), Gaps = 1/112 (0%)
Frame = -3
Query: 560 IFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLS 384
IF+ L ++++I +SNN ++E F +++ L L + + + F S L+TL
Sbjct: 552 IFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLM 611
Query: 383 LARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 228
L N + + G + + L+L N + + P F L +L T + N
Sbjct: 612 LRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSN 663
Score = 41.5 bits (93), Expect = 0.002
Identities = 28/84 (33%), Positives = 39/84 (46%), Gaps = 1/84 (1%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP-EEFISNSPLRTLSLARN 372
L H+ I +SNN L FSN+ L TL L + +R +P F LR L+L N
Sbjct: 774 LRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGN 833
Query: 371 QLRALPRSVLRGQTQLTSLTLSYN 300
+ ++P T L+ L L N
Sbjct: 834 DISSVPEGSFNDLTSLSHLALGTN 857
Score = 33.1 bits (72), Expect = 0.77
Identities = 21/78 (26%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI-RELPE 420
+ N + + + FRG+ ++ +++ NN +++ F L L L L+ ++I R L
Sbjct: 140 LSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVT 199
Query: 419 EFISNSPLRTLSLARNQL 366
F +RTL L N L
Sbjct: 200 SFNHMPKIRTLRLHSNHL 217
>BC040188-1|AAH40188.1| 692|Homo sapiens LOC150356 protein protein.
Length = 692
Score = 77.8 bits (183), Expect = 3e-14
Identities = 55/178 (30%), Positives = 85/178 (47%), Gaps = 1/178 (0%)
Frame = -3
Query: 557 FRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSL 381
FRGL + + +++N L + L +LR L+L+ +++ L P F + L TL+L
Sbjct: 112 FRGLGRLLLLNLASNHLRELPQEALDGLGSLRRLELEGNALEGLRPGTFGALGALATLNL 171
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSL 201
A N L LP +G ++ L LS+NA++ LAPE A L AL + NELQ LP +
Sbjct: 172 AHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGPV 231
Query: 200 FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
S R L + L +N ++ +R L L L ++ +LH L
Sbjct: 232 LSQARGLARLELGHNPLTYAGEEDGLALPGLRELLLDGGALQALGPRAFAHCPRLHTL 289
Score = 68.1 bits (159), Expect = 2e-11
Identities = 46/174 (26%), Positives = 76/174 (43%), Gaps = 1/174 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N + + + F+G+ H+ + + + + E F L L L L + +RELP+E +
Sbjct: 78 NLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELPQEALD 137
Query: 407 N-SPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
LR L L N L L L +L L++NA+ L F L + +
Sbjct: 138 GLGSLRRLELEGNALEGLRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSH 197
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFA 69
N L VL +GL L +SL +N++ + A + L+L +N L +A
Sbjct: 198 NALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYA 251
Score = 66.5 bits (155), Expect = 7e-11
Identities = 51/171 (29%), Positives = 78/171 (45%), Gaps = 1/171 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N+ L F L + + +++N + L F L +R L+L +++ L E ++
Sbjct: 150 NALEGLRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALA 209
Query: 407 NSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
P LR LSL N+L+ALP VL L L L +N + E L L ++DG
Sbjct: 210 GLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAGEEDGLALPGLRELLLDG 269
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
LQ L F+ L T+ LR N++ ++ QG +R L L N L
Sbjct: 270 GALQALGPRAFAHCPRLHTLDLRGNQLD--TLPPLQGPGQLRRLRLQGNPL 318
Score = 62.5 bits (145), Expect = 1e-09
Identities = 48/187 (25%), Positives = 77/187 (41%), Gaps = 1/187 (0%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ RN F + F GL H+ + + + L+ + L L + L + + L
Sbjct: 438 LRRNHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYVYLSDNQLAGLSAA 497
Query: 416 FISNSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+ +P L L L RN+ +P + LR L SL L NAV LAP RAL
Sbjct: 498 ALEGAPRLGYLYLERNRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRWVY 557
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
+ GN + + R L + L N++ + +G ++ L LS N L D
Sbjct: 558 LSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDG 617
Query: 59 LYSPLNQ 39
+ P+ +
Sbjct: 618 AFQPVGR 624
Score = 58.8 bits (136), Expect = 1e-08
Identities = 44/144 (30%), Positives = 69/144 (47%), Gaps = 4/144 (2%)
Frame = -3
Query: 476 LPALRTLQLDLSS--IRELPEEFISNSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLS 306
+P L T +LDL ++ +P P L L L ++ + RG +L L L+
Sbjct: 66 IPEL-TQRLDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLA 124
Query: 305 YNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTF 126
N + EL E L +L ++GN L+ L F L L T++L +N + + F
Sbjct: 125 SNHLRELPQEALDGLGSLRRLELEGNALEGLRPGTFGALGALATLNLAHNALVYLPAMAF 184
Query: 125 QGATSIRTLDLSYNRLA-FAPDSL 57
QG +R L LS+N L+ AP++L
Sbjct: 185 QGLLRVRWLRLSHNALSVLAPEAL 208
Score = 57.2 bits (132), Expect = 4e-08
Identities = 43/150 (28%), Positives = 65/150 (43%), Gaps = 1/150 (0%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ N+ YL + F+GL ++ +++S+N L + LPALR L L + ++ LP
Sbjct: 171 LAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGP 230
Query: 416 FISNS-PLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+S + L L L N L L L L A+ L P FA L T
Sbjct: 231 VLSQARGLARLELGHNPLTYAGEEDGLALPGLRELLLDGGALQALGPRAFAHCPRLHTLD 290
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKI 150
+ GN+L LP G L + L+ N +
Sbjct: 291 LRGNQLDTLPP--LQGPGQLRRLRLQGNPL 318
Score = 44.8 bits (101), Expect = 2e-04
Identities = 21/72 (29%), Positives = 40/72 (55%)
Frame = -3
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
+ GN L+V+P + F G+ +LT + LR+ ++ +++ F+G + L+L+ N L P
Sbjct: 75 LQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELPQE 134
Query: 59 LYSPLNQLHKLQ 24
L L +L+
Sbjct: 135 ALDGLGSLRRLE 146
Score = 43.2 bits (97), Expect = 7e-04
Identities = 37/141 (26%), Positives = 59/141 (41%), Gaps = 1/141 (0%)
Frame = -3
Query: 476 LPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNA 297
+P R + ++ +P F S++ L L L RN ++PR+ G L SL L +
Sbjct: 409 VPESRHSSCEGCGLQAVPRGFPSDTQL--LDLRRNHFPSVPRAAFPGLGHLVSLHLQHCG 466
Query: 296 VAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGA 117
+AEL A L L + N+L L + G L + L N+ + +
Sbjct: 467 IAELEAGALAGLGRLIYVYLSDNQLAGLSAAALEGAPRLGYLYLERNRFLQVPGAALRAL 526
Query: 116 TSIRTLDLSYNRL-AFAPDSL 57
S+ +L L N + AP L
Sbjct: 527 PSLFSLHLQDNAVDRLAPGDL 547
Score = 39.9 bits (89), Expect = 0.007
Identities = 27/82 (32%), Positives = 45/82 (54%), Gaps = 3/82 (3%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLP-ALRTLQLDLSSIREL-PEE 417
RN R + + GL + E+++S N L++ F + +L+ L L+ S + ++ P
Sbjct: 584 RNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQHLFLNSSGLEQICPGA 643
Query: 416 FISNSP-LRTLSLARNQLRALP 354
F P L++L L +NQLRALP
Sbjct: 644 FSGLGPGLQSLHLQKNQLRALP 665
>AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein.
Length = 1523
Score = 77.8 bits (183), Expect = 3e-14
Identities = 41/129 (31%), Positives = 72/129 (55%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
+ L +N ++A+P +L + +S N ++++AP+ F L++L + V+ GN++ +
Sbjct: 312 IRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIA 371
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHK 30
LF GL +L + L NKI+ + +NTFQ ++ L L N+L L++P L
Sbjct: 372 KGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAP---LQS 428
Query: 29 LQTLTLAWN 3
+QTL LA N
Sbjct: 429 IQTLHLAQN 437
Score = 74.9 bits (176), Expect = 2e-13
Identities = 43/135 (31%), Positives = 75/135 (55%), Gaps = 2/135 (1%)
Frame = -3
Query: 482 SNLP-ALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTL 309
+NLP + ++L+ +SI+ +P F L+ + +++NQ+ + +G LTSL L
Sbjct: 303 ANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVL 362
Query: 308 SYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNT 129
N + E+A LF L +L+ +++ N++ L + F L+NL +SL +NK+ IS
Sbjct: 363 YGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGL 422
Query: 128 FQGATSIRTLDLSYN 84
F SI+TL L+ N
Sbjct: 423 FAPLQSIQTLHLAQN 437
Score = 70.1 bits (164), Expect = 6e-12
Identities = 45/161 (27%), Positives = 77/161 (47%), Gaps = 2/161 (1%)
Frame = -3
Query: 554 RGLD-HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSL 381
RG+ + + + + N + + F+ L LR L L+ + + + F L L L
Sbjct: 57 RGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRL 116
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSL 201
+N+L+ LP + + +LT L LS N + + + F + ++ +D N + + D
Sbjct: 117 NKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGA 176
Query: 200 FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
F LR+L ++L NN IS I + +F IRTL L N L
Sbjct: 177 FRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 217
Score = 67.3 bits (157), Expect = 4e-11
Identities = 42/137 (30%), Positives = 63/137 (45%)
Frame = -3
Query: 437 IRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 258
+R +P N+ L L RN + + + G L L L N V+ + F DL+
Sbjct: 52 LRAVPRGIPRNA--ERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLK 109
Query: 257 ALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
LE ++ N+LQVLP+ LF LT + L N+I I F+G T ++ L L N +
Sbjct: 110 QLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHI 169
Query: 77 AFAPDSLYSPLNQLHKL 27
+ D + L L L
Sbjct: 170 SCIEDGAFRALRDLEIL 186
Score = 63.3 bits (147), Expect = 6e-10
Identities = 37/130 (28%), Positives = 66/130 (50%), Gaps = 1/130 (0%)
Frame = -3
Query: 389 LSLARNQLRALPRS-VLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVL 213
L L N++ L + + + L + LS N + E+ F +++ ++ GN+L+ +
Sbjct: 537 LRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETV 596
Query: 212 PDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLH 33
+F GL L T+ LR+N IS +S +TF G +S+R L L NR+ ++ L L
Sbjct: 597 HGRVFRGLSGLKTLMLRSNLISCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLS 656
Query: 32 KLQTLTLAWN 3
+ L+ +N
Sbjct: 657 TINLLSNPFN 666
Score = 55.2 bits (127), Expect = 2e-07
Identities = 33/79 (41%), Positives = 45/79 (56%)
Frame = -3
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
++GN L +P L S LR+LT + L NN IS+++ TF + + TL LSYNRL P
Sbjct: 759 LEGNHLTAVPREL-SALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVH 817
Query: 59 LYSPLNQLHKLQTLTLAWN 3
+ N L L+ LTL N
Sbjct: 818 AF---NGLRSLRVLTLHGN 833
Score = 54.0 bits (124), Expect = 4e-07
Identities = 32/115 (27%), Positives = 53/115 (46%)
Frame = -3
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
LRA+PR + R +L L N + + FA L+ L ++ N++ V+ F L
Sbjct: 52 LRAVPRGIPRNAERLD---LDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDL 108
Query: 188 RNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
+ L + L NK+ V+ FQ + LDLS N++ P + + + LQ
Sbjct: 109 KQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQ 163
Score = 51.6 bits (118), Expect = 2e-06
Identities = 26/105 (24%), Positives = 55/105 (52%)
Frame = -3
Query: 398 LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 219
LR ++L+ N+++ + G + L L+ N + + +F L L+T ++ N +
Sbjct: 559 LRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIS 618
Query: 218 VLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
+ + F+GL ++ +SL +N+I+ I+ F S+ T++L N
Sbjct: 619 CVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSN 663
Score = 50.0 bits (114), Expect = 6e-06
Identities = 26/103 (25%), Positives = 51/103 (49%)
Frame = -3
Query: 458 LQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAP 279
L L+ + + +P E + L + L+ N + L + L++L LSYN + +
Sbjct: 757 LYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPV 816
Query: 278 ELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKI 150
F LR+L + GN++ +P+ F+ L +L+ ++L N +
Sbjct: 817 HAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPL 859
Score = 45.6 bits (103), Expect = 1e-04
Identities = 24/100 (24%), Positives = 49/100 (49%)
Frame = -3
Query: 326 LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKIS 147
+ + L N++ + F + L+ + N++ + F GL++LT++ L NKI+
Sbjct: 309 IVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKIT 368
Query: 146 VISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
I+ F G S++ L L+ N++ + + L L+ L
Sbjct: 369 EIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLL 408
Score = 42.7 bits (96), Expect = 0.001
Identities = 28/112 (25%), Positives = 52/112 (46%), Gaps = 1/112 (0%)
Frame = -3
Query: 560 IFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLS 384
IF+ L ++++I +SNN ++E F +++ L L + + + F S L+TL
Sbjct: 552 IFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLM 611
Query: 383 LARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 228
L N + + G + + L+L N + + P F L +L T + N
Sbjct: 612 LRSNLISCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSN 663
Score = 41.5 bits (93), Expect = 0.002
Identities = 28/84 (33%), Positives = 39/84 (46%), Gaps = 1/84 (1%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP-EEFISNSPLRTLSLARN 372
L H+ I +SNN L FSN+ L TL L + +R +P F LR L+L N
Sbjct: 774 LRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGN 833
Query: 371 QLRALPRSVLRGQTQLTSLTLSYN 300
+ ++P T L+ L L N
Sbjct: 834 DISSVPEGSFNDLTSLSHLALGTN 857
Score = 33.1 bits (72), Expect = 0.77
Identities = 21/78 (26%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI-RELPE 420
+ N + + + FRG+ ++ +++ NN +++ F L L L L+ ++I R L
Sbjct: 140 LSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVT 199
Query: 419 EFISNSPLRTLSLARNQL 366
F +RTL L N L
Sbjct: 200 SFNHMPKIRTLRLHSNHL 217
>AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein.
Length = 1523
Score = 77.8 bits (183), Expect = 3e-14
Identities = 41/129 (31%), Positives = 72/129 (55%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
+ L +N ++A+P +L + +S N ++++AP+ F L++L + V+ GN++ +
Sbjct: 312 IRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIA 371
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHK 30
LF GL +L + L NKI+ + +NTFQ ++ L L N+L L++P L
Sbjct: 372 KGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAP---LQS 428
Query: 29 LQTLTLAWN 3
+QTL LA N
Sbjct: 429 IQTLHLAQN 437
Score = 74.9 bits (176), Expect = 2e-13
Identities = 43/135 (31%), Positives = 75/135 (55%), Gaps = 2/135 (1%)
Frame = -3
Query: 482 SNLP-ALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTL 309
+NLP + ++L+ +SI+ +P F L+ + +++NQ+ + +G LTSL L
Sbjct: 303 ANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVL 362
Query: 308 SYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNT 129
N + E+A LF L +L+ +++ N++ L + F L+NL +SL +NK+ IS
Sbjct: 363 YGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGL 422
Query: 128 FQGATSIRTLDLSYN 84
F SI+TL L+ N
Sbjct: 423 FAPLQSIQTLHLAQN 437
Score = 70.1 bits (164), Expect = 6e-12
Identities = 45/161 (27%), Positives = 77/161 (47%), Gaps = 2/161 (1%)
Frame = -3
Query: 554 RGLD-HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSL 381
RG+ + + + + N + + F+ L LR L L+ + + + F L L L
Sbjct: 57 RGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRL 116
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSL 201
+N+L+ LP + + +LT L LS N + + + F + ++ +D N + + D
Sbjct: 117 NKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGA 176
Query: 200 FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
F LR+L ++L NN IS I + +F IRTL L N L
Sbjct: 177 FRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 217
Score = 67.3 bits (157), Expect = 4e-11
Identities = 42/137 (30%), Positives = 63/137 (45%)
Frame = -3
Query: 437 IRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 258
+R +P N+ L L RN + + + G L L L N V+ + F DL+
Sbjct: 52 LRAVPRGIPRNA--ERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLK 109
Query: 257 ALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
LE ++ N+LQVLP+ LF LT + L N+I I F+G T ++ L L N +
Sbjct: 110 QLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHI 169
Query: 77 AFAPDSLYSPLNQLHKL 27
+ D + L L L
Sbjct: 170 SCIEDGAFRALRDLEIL 186
Score = 61.7 bits (143), Expect = 2e-09
Identities = 36/130 (27%), Positives = 65/130 (50%), Gaps = 1/130 (0%)
Frame = -3
Query: 389 LSLARNQLRALPRS-VLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVL 213
L L N++ L + + + L + LS N + E+ F +++ ++ GN+L+ +
Sbjct: 537 LRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETV 596
Query: 212 PDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLH 33
+F GL L T+ LR+N I +S +TF G +S+R L L NR+ ++ L L
Sbjct: 597 HGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLS 656
Query: 32 KLQTLTLAWN 3
+ L+ +N
Sbjct: 657 TINLLSNPFN 666
Score = 55.2 bits (127), Expect = 2e-07
Identities = 33/79 (41%), Positives = 45/79 (56%)
Frame = -3
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
++GN L +P L S LR+LT + L NN IS+++ TF + + TL LSYNRL P
Sbjct: 759 LEGNHLTAVPREL-SALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVH 817
Query: 59 LYSPLNQLHKLQTLTLAWN 3
+ N L L+ LTL N
Sbjct: 818 AF---NGLRSLRVLTLHGN 833
Score = 54.0 bits (124), Expect = 4e-07
Identities = 32/115 (27%), Positives = 53/115 (46%)
Frame = -3
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
LRA+PR + R +L L N + + FA L+ L ++ N++ V+ F L
Sbjct: 52 LRAVPRGIPRNAERLD---LDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDL 108
Query: 188 RNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
+ L + L NK+ V+ FQ + LDLS N++ P + + + LQ
Sbjct: 109 KQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQ 163
Score = 50.8 bits (116), Expect = 4e-06
Identities = 26/105 (24%), Positives = 55/105 (52%)
Frame = -3
Query: 398 LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 219
LR ++L+ N+++ + G + L L+ N + + +F L L+T ++ N +
Sbjct: 559 LRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIG 618
Query: 218 VLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
+ + F+GL ++ +SL +N+I+ I+ F S+ T++L N
Sbjct: 619 CVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSN 663
Score = 50.0 bits (114), Expect = 6e-06
Identities = 26/103 (25%), Positives = 51/103 (49%)
Frame = -3
Query: 458 LQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAP 279
L L+ + + +P E + L + L+ N + L + L++L LSYN + +
Sbjct: 757 LYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPV 816
Query: 278 ELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKI 150
F LR+L + GN++ +P+ F+ L +L+ ++L N +
Sbjct: 817 HAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPL 859
Score = 45.6 bits (103), Expect = 1e-04
Identities = 24/100 (24%), Positives = 49/100 (49%)
Frame = -3
Query: 326 LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKIS 147
+ + L N++ + F + L+ + N++ + F GL++LT++ L NKI+
Sbjct: 309 IVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKIT 368
Query: 146 VISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
I+ F G S++ L L+ N++ + + L L+ L
Sbjct: 369 EIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLL 408
Score = 42.3 bits (95), Expect = 0.001
Identities = 28/112 (25%), Positives = 52/112 (46%), Gaps = 1/112 (0%)
Frame = -3
Query: 560 IFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLS 384
IF+ L ++++I +SNN ++E F +++ L L + + + F S L+TL
Sbjct: 552 IFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLM 611
Query: 383 LARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 228
L N + + G + + L+L N + + P F L +L T + N
Sbjct: 612 LRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSN 663
Score = 41.5 bits (93), Expect = 0.002
Identities = 28/84 (33%), Positives = 39/84 (46%), Gaps = 1/84 (1%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP-EEFISNSPLRTLSLARN 372
L H+ I +SNN L FSN+ L TL L + +R +P F LR L+L N
Sbjct: 774 LRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGN 833
Query: 371 QLRALPRSVLRGQTQLTSLTLSYN 300
+ ++P T L+ L L N
Sbjct: 834 DISSVPEGSFNDLTSLSHLALGTN 857
Score = 33.1 bits (72), Expect = 0.77
Identities = 21/78 (26%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI-RELPE 420
+ N + + + FRG+ ++ +++ NN +++ F L L L L+ ++I R L
Sbjct: 140 LSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVT 199
Query: 419 EFISNSPLRTLSLARNQL 366
F +RTL L N L
Sbjct: 200 SFNHMPKIRTLRLHSNHL 217
>AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein.
Length = 1559
Score = 77.8 bits (183), Expect = 3e-14
Identities = 41/129 (31%), Positives = 72/129 (55%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
+ L +N ++A+P +L + +S N ++++AP+ F L++L + V+ GN++ +
Sbjct: 348 IRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIA 407
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHK 30
LF GL +L + L NKI+ + +NTFQ ++ L L N+L L++P L
Sbjct: 408 KGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAP---LQS 464
Query: 29 LQTLTLAWN 3
+QTL LA N
Sbjct: 465 IQTLHLAQN 473
Score = 74.9 bits (176), Expect = 2e-13
Identities = 43/135 (31%), Positives = 75/135 (55%), Gaps = 2/135 (1%)
Frame = -3
Query: 482 SNLP-ALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTL 309
+NLP + ++L+ +SI+ +P F L+ + +++NQ+ + +G LTSL L
Sbjct: 339 ANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVL 398
Query: 308 SYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNT 129
N + E+A LF L +L+ +++ N++ L + F L+NL +SL +NK+ IS
Sbjct: 399 YGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGL 458
Query: 128 FQGATSIRTLDLSYN 84
F SI+TL L+ N
Sbjct: 459 FAPLQSIQTLHLAQN 473
Score = 70.1 bits (164), Expect = 6e-12
Identities = 45/161 (27%), Positives = 77/161 (47%), Gaps = 2/161 (1%)
Frame = -3
Query: 554 RGLD-HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSL 381
RG+ + + + + N + + F+ L LR L L+ + + + F L L L
Sbjct: 93 RGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRL 152
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSL 201
+N+L+ LP + + +LT L LS N + + + F + ++ +D N + + D
Sbjct: 153 NKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGA 212
Query: 200 FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
F LR+L ++L NN IS I + +F IRTL L N L
Sbjct: 213 FRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 253
Score = 67.3 bits (157), Expect = 4e-11
Identities = 42/137 (30%), Positives = 63/137 (45%)
Frame = -3
Query: 437 IRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 258
+R +P N+ L L RN + + + G L L L N V+ + F DL+
Sbjct: 88 LRAVPRGIPRNA--ERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLK 145
Query: 257 ALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
LE ++ N+LQVLP+ LF LT + L N+I I F+G T ++ L L N +
Sbjct: 146 QLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHI 205
Query: 77 AFAPDSLYSPLNQLHKL 27
+ D + L L L
Sbjct: 206 SCIEDGAFRALRDLEIL 222
Score = 61.7 bits (143), Expect = 2e-09
Identities = 36/130 (27%), Positives = 65/130 (50%), Gaps = 1/130 (0%)
Frame = -3
Query: 389 LSLARNQLRALPRS-VLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVL 213
L L N++ L + + + L + LS N + E+ F +++ ++ GN+L+ +
Sbjct: 573 LRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETV 632
Query: 212 PDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLH 33
+F GL L T+ LR+N I +S +TF G +S+R L L NR+ ++ L L
Sbjct: 633 HGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLS 692
Query: 32 KLQTLTLAWN 3
+ L+ +N
Sbjct: 693 TINLLSNPFN 702
Score = 55.2 bits (127), Expect = 2e-07
Identities = 33/79 (41%), Positives = 45/79 (56%)
Frame = -3
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
++GN L +P L S LR+LT + L NN IS+++ TF + + TL LSYNRL P
Sbjct: 795 LEGNHLTAVPREL-SALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVH 853
Query: 59 LYSPLNQLHKLQTLTLAWN 3
+ N L L+ LTL N
Sbjct: 854 AF---NGLRSLRVLTLHGN 869
Score = 54.0 bits (124), Expect = 4e-07
Identities = 32/115 (27%), Positives = 53/115 (46%)
Frame = -3
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
LRA+PR + R +L L N + + FA L+ L ++ N++ V+ F L
Sbjct: 88 LRAVPRGIPRNAERLD---LDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDL 144
Query: 188 RNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
+ L + L NK+ V+ FQ + LDLS N++ P + + + LQ
Sbjct: 145 KQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQ 199
Score = 50.8 bits (116), Expect = 4e-06
Identities = 26/105 (24%), Positives = 55/105 (52%)
Frame = -3
Query: 398 LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 219
LR ++L+ N+++ + G + L L+ N + + +F L L+T ++ N +
Sbjct: 595 LRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIG 654
Query: 218 VLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
+ + F+GL ++ +SL +N+I+ I+ F S+ T++L N
Sbjct: 655 CVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSN 699
Score = 50.0 bits (114), Expect = 6e-06
Identities = 26/103 (25%), Positives = 51/103 (49%)
Frame = -3
Query: 458 LQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAP 279
L L+ + + +P E + L + L+ N + L + L++L LSYN + +
Sbjct: 793 LYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPV 852
Query: 278 ELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKI 150
F LR+L + GN++ +P+ F+ L +L+ ++L N +
Sbjct: 853 HAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPL 895
Score = 45.6 bits (103), Expect = 1e-04
Identities = 24/100 (24%), Positives = 49/100 (49%)
Frame = -3
Query: 326 LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKIS 147
+ + L N++ + F + L+ + N++ + F GL++LT++ L NKI+
Sbjct: 345 IVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKIT 404
Query: 146 VISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
I+ F G S++ L L+ N++ + + L L+ L
Sbjct: 405 EIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLL 444
Score = 42.3 bits (95), Expect = 0.001
Identities = 28/112 (25%), Positives = 52/112 (46%), Gaps = 1/112 (0%)
Frame = -3
Query: 560 IFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLS 384
IF+ L ++++I +SNN ++E F +++ L L + + + F S L+TL
Sbjct: 588 IFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLM 647
Query: 383 LARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 228
L N + + G + + L+L N + + P F L +L T + N
Sbjct: 648 LRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSN 699
Score = 41.5 bits (93), Expect = 0.002
Identities = 28/84 (33%), Positives = 39/84 (46%), Gaps = 1/84 (1%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP-EEFISNSPLRTLSLARN 372
L H+ I +SNN L FSN+ L TL L + +R +P F LR L+L N
Sbjct: 810 LRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGN 869
Query: 371 QLRALPRSVLRGQTQLTSLTLSYN 300
+ ++P T L+ L L N
Sbjct: 870 DISSVPEGSFNDLTSLSHLALGTN 893
Score = 33.1 bits (72), Expect = 0.77
Identities = 21/78 (26%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI-RELPE 420
+ N + + + FRG+ ++ +++ NN +++ F L L L L+ ++I R L
Sbjct: 176 LSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVT 235
Query: 419 EFISNSPLRTLSLARNQL 366
F +RTL L N L
Sbjct: 236 SFNHMPKIRTLRLHSNHL 253
>BC131897-1|AAI31898.1| 420|Homo sapiens LRRC4B protein protein.
Length = 420
Score = 77.0 bits (181), Expect = 5e-14
Identities = 54/200 (27%), Positives = 93/200 (46%), Gaps = 2/200 (1%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ +N R ++ F GL + +++ +N T+ F L LR L L + I +P
Sbjct: 117 LSKNLVRKIEVGAFNGLPSLNTLELFDNRLTTVPTQAFEYLSKLRELWLRNNPIESIPSY 176
Query: 416 FISNSP-LRTLSLAR-NQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETF 243
+ P LR L L +L + + G L L L + ++ P L A +R LE
Sbjct: 177 AFNRVPSLRRLDLGELKRLEYISEAAFEGLVNLRYLNLGMCNLKDI-PNLTALVR-LEEL 234
Query: 242 VMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPD 63
+ GN L ++ F GL +L + L + +++ I N F S+ L+LS+N L P
Sbjct: 235 ELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLKSLEELNLSHNNLMSLPH 294
Query: 62 SLYSPLNQLHKLQTLTLAWN 3
L++PL++L ++ W+
Sbjct: 295 DLFTPLHRLERVHLNHNPWH 314
Score = 52.0 bits (119), Expect = 2e-06
Identities = 40/138 (28%), Positives = 59/138 (42%), Gaps = 1/138 (0%)
Frame = -3
Query: 437 IRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 258
+ E+P N+ R L+L N ++ + + L L LS N V ++ F L
Sbjct: 77 LAEVPASIPVNT--RYLNLQENGIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLP 134
Query: 257 ALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDL-SYNR 81
+L T + N L +P F L L + LRNN I I F S+R LDL R
Sbjct: 135 SLNTLELFDNRLTTVPTQAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKR 194
Query: 80 LAFAPDSLYSPLNQLHKL 27
L + ++ + L L L
Sbjct: 195 LEYISEAAFEGLVNLRYL 212
>BC041374-1|AAH41374.3| 640|Homo sapiens LRRC4C protein protein.
Length = 640
Score = 77.0 bits (181), Expect = 5e-14
Identities = 53/200 (26%), Positives = 91/200 (45%), Gaps = 2/200 (1%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ RN R ++ F GL ++ +++ +N T+ F L L+ L L + I +P
Sbjct: 107 LSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSY 166
Query: 416 FISNSP-LRTLSLAR-NQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETF 243
+ P LR L L +L + G + L L L+ + E+ P L L L+
Sbjct: 167 AFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREI-PNL-TPLIKLDEL 224
Query: 242 VMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPD 63
+ GN L + F GL +L + + ++I VI N F S+ ++L++N L P
Sbjct: 225 DLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPH 284
Query: 62 SLYSPLNQLHKLQTLTLAWN 3
L++PL+ L ++ WN
Sbjct: 285 DLFTPLHHLERIHLHHNPWN 304
Score = 57.6 bits (133), Expect = 3e-08
Identities = 41/139 (29%), Positives = 65/139 (46%), Gaps = 1/139 (0%)
Frame = -3
Query: 440 SIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADL 261
++RE+P+ +N+ R L+L NQ++ + + + L L LS N + + F L
Sbjct: 66 NLREVPDGISTNT--RLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGL 123
Query: 260 RALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDL-SYN 84
L T + N L +P+ F L L + LRNN I I F S+R LDL
Sbjct: 124 ANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELK 183
Query: 83 RLAFAPDSLYSPLNQLHKL 27
RL++ + + L+ L L
Sbjct: 184 RLSYISEGAFEGLSNLRYL 202
>BC036337-1|AAH36337.1| 811|Homo sapiens KIAA0644 gene product
protein.
Length = 811
Score = 77.0 bits (181), Expect = 5e-14
Identities = 57/190 (30%), Positives = 90/190 (47%), Gaps = 3/190 (1%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FI 411
N L F GL+ + ++++ N L +AVF+ L L L L+ + IR L + F
Sbjct: 141 NEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFA 200
Query: 410 SNSPLRTLSLARNQLRALPR--SVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVM 237
LR L+L+ N+L+ R + L+SL LS N++ L P +F L L +
Sbjct: 201 QLGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSL 260
Query: 236 DGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
GN+L L F GL L + L N++S + + S+ LDLS N L+ +
Sbjct: 261 RGNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHPAT 320
Query: 56 YSPLNQLHKL 27
+ L +L +L
Sbjct: 321 FGHLGRLREL 330
Score = 75.4 bits (177), Expect = 1e-13
Identities = 53/156 (33%), Positives = 76/156 (48%), Gaps = 3/156 (1%)
Frame = -3
Query: 485 FSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTL 309
F L LR L L + IR L P+ F S L L L N L+AL L +L L
Sbjct: 79 FHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALAPGTLAPLRKLRILYA 138
Query: 308 SYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNT 129
+ N ++ L+ F L +L +DGN L LPD++F+ L NL + L +N+I + N
Sbjct: 139 NGNEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNA 198
Query: 128 FQGATSIRTLDLSYNRL--AFAPDSLYSPLNQLHKL 27
F +R L+LS N L + + ++PL L L
Sbjct: 199 FAQLGKLRFLNLSANELQPSLRHAATFAPLRSLSSL 234
Score = 75.4 bits (177), Expect = 1e-13
Identities = 54/197 (27%), Positives = 91/197 (46%), Gaps = 3/197 (1%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N+ L +F L ++ + + +N L + F+ L LR L L + ++ +
Sbjct: 165 NALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQLGKLRFLNLSANELQPSLRHAAT 224
Query: 407 NSPLRTLS---LARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVM 237
+PLR+LS L+ N L+ L + + +L L+L N + LAPE F L AL +
Sbjct: 225 FAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSLRGNQLTHLAPEAFWGLEALRELRL 284
Query: 236 DGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
+GN L LP +L L +L + L N++S + TF +R L L N L+ +
Sbjct: 285 EGNRLSQLPTALLEPLHSLEALDLSGNELSALHPATFGHLGRLRELSLRNNALSALSGDI 344
Query: 56 YSPLNQLHKLQTLTLAW 6
++ L++L W
Sbjct: 345 FAASPALYRLDLDGNGW 361
Score = 64.5 bits (150), Expect = 3e-10
Identities = 43/136 (31%), Positives = 63/136 (46%), Gaps = 2/136 (1%)
Frame = -3
Query: 437 IRELPEEFISNSP--LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFAD 264
+R +P+ SP + T SL N + + QL L L YN + L P+ F
Sbjct: 46 LRVVPKTSSLPSPHDVLTYSLGGNFITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEK 105
Query: 263 LRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
L LE + N LQ L + LR L + N+IS +S +F+G S+ L L N
Sbjct: 106 LSRLEELYLGNNLLQALAPGTLAPLRKLRILYANGNEISRLSRGSFEGLESLVKLRLDGN 165
Query: 83 RLAFAPDSLYSPLNQL 36
L PD++++PL L
Sbjct: 166 ALGALPDAVFAPLGNL 181
Score = 30.3 bits (65), Expect = 5.4
Identities = 20/67 (29%), Positives = 33/67 (49%), Gaps = 1/67 (1%)
Frame = -3
Query: 224 LQVLPD-SLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSP 48
L+V+P S ++ T SL N I+ I+ F +R LDL YN++ +
Sbjct: 46 LRVVPKTSSLPSPHDVLTYSLGGNFITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEK 105
Query: 47 LNQLHKL 27
L++L +L
Sbjct: 106 LSRLEEL 112
>BC032460-1|AAH32460.1| 634|Homo sapiens LRRC4B protein protein.
Length = 634
Score = 77.0 bits (181), Expect = 5e-14
Identities = 54/200 (27%), Positives = 93/200 (46%), Gaps = 2/200 (1%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ +N R ++ F GL + +++ +N T+ F L LR L L + I +P
Sbjct: 117 LSKNLVRKIEVGAFNGLPSLNTLELFDNRLTTVPTQAFEYLSKLRELWLRNNPIESIPSY 176
Query: 416 FISNSP-LRTLSLAR-NQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETF 243
+ P LR L L +L + + G L L L + ++ P L A +R LE
Sbjct: 177 AFNRVPSLRRLDLGELKRLEYISEAAFEGLVNLRYLNLGMCNLKDI-PNLTALVR-LEEL 234
Query: 242 VMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPD 63
+ GN L ++ F GL +L + L + +++ I N F S+ L+LS+N L P
Sbjct: 235 ELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLKSLEELNLSHNNLMSLPH 294
Query: 62 SLYSPLNQLHKLQTLTLAWN 3
L++PL++L ++ W+
Sbjct: 295 DLFTPLHRLERVHLNHNPWH 314
Score = 52.0 bits (119), Expect = 2e-06
Identities = 40/138 (28%), Positives = 59/138 (42%), Gaps = 1/138 (0%)
Frame = -3
Query: 437 IRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 258
+ E+P N+ R L+L N ++ + + L L LS N V ++ F L
Sbjct: 77 LAEVPASIPVNT--RYLNLQENGIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLP 134
Query: 257 ALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDL-SYNR 81
+L T + N L +P F L L + LRNN I I F S+R LDL R
Sbjct: 135 SLNTLELFDNRLTTVPTQAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKR 194
Query: 80 LAFAPDSLYSPLNQLHKL 27
L + ++ + L L L
Sbjct: 195 LEYISEAAFEGLVNLRYL 212
>AY358293-1|AAQ88660.1| 640|Homo sapiens LNKM292 protein.
Length = 640
Score = 77.0 bits (181), Expect = 5e-14
Identities = 53/200 (26%), Positives = 91/200 (45%), Gaps = 2/200 (1%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ RN R ++ F GL ++ +++ +N T+ F L L+ L L + I +P
Sbjct: 107 LSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSY 166
Query: 416 FISNSP-LRTLSLAR-NQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETF 243
+ P LR L L +L + G + L L L+ + E+ P L L L+
Sbjct: 167 AFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREI-PNL-TPLIKLDEL 224
Query: 242 VMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPD 63
+ GN L + F GL +L + + ++I VI N F S+ ++L++N L P
Sbjct: 225 DLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPH 284
Query: 62 SLYSPLNQLHKLQTLTLAWN 3
L++PL+ L ++ WN
Sbjct: 285 DLFTPLHHLERIHLHHNPWN 304
Score = 57.6 bits (133), Expect = 3e-08
Identities = 41/139 (29%), Positives = 65/139 (46%), Gaps = 1/139 (0%)
Frame = -3
Query: 440 SIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADL 261
++RE+P+ +N+ R L+L NQ++ + + + L L LS N + + F L
Sbjct: 66 NLREVPDGISTNT--RLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGL 123
Query: 260 RALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDL-SYN 84
L T + N L +P+ F L L + LRNN I I F S+R LDL
Sbjct: 124 ANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELK 183
Query: 83 RLAFAPDSLYSPLNQLHKL 27
RL++ + + L+ L L
Sbjct: 184 RLSYISEGAFEGLSNLRYL 202
>AB046800-1|BAB13406.1| 640|Homo sapiens KIAA1580 protein protein.
Length = 640
Score = 77.0 bits (181), Expect = 5e-14
Identities = 53/200 (26%), Positives = 91/200 (45%), Gaps = 2/200 (1%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ RN R ++ F GL ++ +++ +N T+ F L L+ L L + I +P
Sbjct: 107 LSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSY 166
Query: 416 FISNSP-LRTLSLAR-NQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETF 243
+ P LR L L +L + G + L L L+ + E+ P L L L+
Sbjct: 167 AFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREI-PNL-TPLIKLDEL 224
Query: 242 VMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPD 63
+ GN L + F GL +L + + ++I VI N F S+ ++L++N L P
Sbjct: 225 DLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPH 284
Query: 62 SLYSPLNQLHKLQTLTLAWN 3
L++PL+ L ++ WN
Sbjct: 285 DLFTPLHHLERIHLHHNPWN 304
Score = 57.6 bits (133), Expect = 3e-08
Identities = 41/139 (29%), Positives = 65/139 (46%), Gaps = 1/139 (0%)
Frame = -3
Query: 440 SIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADL 261
++RE+P+ +N+ R L+L NQ++ + + + L L LS N + + F L
Sbjct: 66 NLREVPDGISTNT--RLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGL 123
Query: 260 RALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDL-SYN 84
L T + N L +P+ F L L + LRNN I I F S+R LDL
Sbjct: 124 ANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELK 183
Query: 83 RLAFAPDSLYSPLNQLHKL 27
RL++ + + L+ L L
Sbjct: 184 RLSYISEGAFEGLSNLRYL 202
>AB014544-1|BAA31619.2| 887|Homo sapiens KIAA0644 protein protein.
Length = 887
Score = 77.0 bits (181), Expect = 5e-14
Identities = 57/190 (30%), Positives = 90/190 (47%), Gaps = 3/190 (1%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FI 411
N L F GL+ + ++++ N L +AVF+ L L L L+ + IR L + F
Sbjct: 217 NEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFA 276
Query: 410 SNSPLRTLSLARNQLRALPR--SVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVM 237
LR L+L+ N+L+ R + L+SL LS N++ L P +F L L +
Sbjct: 277 QLGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSL 336
Query: 236 DGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
GN+L L F GL L + L N++S + + S+ LDLS N L+ +
Sbjct: 337 RGNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHPAT 396
Query: 56 YSPLNQLHKL 27
+ L +L +L
Sbjct: 397 FGHLGRLREL 406
Score = 75.4 bits (177), Expect = 1e-13
Identities = 53/156 (33%), Positives = 76/156 (48%), Gaps = 3/156 (1%)
Frame = -3
Query: 485 FSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTL 309
F L LR L L + IR L P+ F S L L L N L+AL L +L L
Sbjct: 155 FHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALAPGTLAPLRKLRILYA 214
Query: 308 SYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNT 129
+ N ++ L+ F L +L +DGN L LPD++F+ L NL + L +N+I + N
Sbjct: 215 NGNEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNA 274
Query: 128 FQGATSIRTLDLSYNRL--AFAPDSLYSPLNQLHKL 27
F +R L+LS N L + + ++PL L L
Sbjct: 275 FAQLGKLRFLNLSANELQPSLRHAATFAPLRSLSSL 310
Score = 75.4 bits (177), Expect = 1e-13
Identities = 54/197 (27%), Positives = 91/197 (46%), Gaps = 3/197 (1%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N+ L +F L ++ + + +N L + F+ L LR L L + ++ +
Sbjct: 241 NALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQLGKLRFLNLSANELQPSLRHAAT 300
Query: 407 NSPLRTLS---LARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVM 237
+PLR+LS L+ N L+ L + + +L L+L N + LAPE F L AL +
Sbjct: 301 FAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSLRGNQLTHLAPEAFWGLEALRELRL 360
Query: 236 DGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
+GN L LP +L L +L + L N++S + TF +R L L N L+ +
Sbjct: 361 EGNRLSQLPTALLEPLHSLEALDLSGNELSALHPATFGHLGRLRELSLRNNALSALSGDI 420
Query: 56 YSPLNQLHKLQTLTLAW 6
++ L++L W
Sbjct: 421 FAASPALYRLDLDGNGW 437
Score = 64.5 bits (150), Expect = 3e-10
Identities = 43/136 (31%), Positives = 63/136 (46%), Gaps = 2/136 (1%)
Frame = -3
Query: 437 IRELPEEFISNSP--LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFAD 264
+R +P+ SP + T SL N + + QL L L YN + L P+ F
Sbjct: 122 LRVVPKTSSLPSPHDVLTYSLGGNFITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEK 181
Query: 263 LRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
L LE + N LQ L + LR L + N+IS +S +F+G S+ L L N
Sbjct: 182 LSRLEELYLGNNLLQALAPGTLAPLRKLRILYANGNEISRLSRGSFEGLESLVKLRLDGN 241
Query: 83 RLAFAPDSLYSPLNQL 36
L PD++++PL L
Sbjct: 242 ALGALPDAVFAPLGNL 257
Score = 30.3 bits (65), Expect = 5.4
Identities = 20/67 (29%), Positives = 33/67 (49%), Gaps = 1/67 (1%)
Frame = -3
Query: 224 LQVLPD-SLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSP 48
L+V+P S ++ T SL N I+ I+ F +R LDL YN++ +
Sbjct: 122 LRVVPKTSSLPSPHDVLTYSLGGNFITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEK 181
Query: 47 LNQLHKL 27
L++L +L
Sbjct: 182 LSRLEEL 188
>BC030608-1|AAH30608.1| 661|Homo sapiens podocan protein.
Length = 661
Score = 76.6 bits (180), Expect = 6e-14
Identities = 61/203 (30%), Positives = 95/203 (46%), Gaps = 5/203 (2%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNN---VPLTLKEAVFSNLPALRTLQLDLSSIREL 426
++ N + E F ++E+ +S N P ++A F L LR+L L + + L
Sbjct: 435 ILHNQITGIGREDFATTYFLEELNLSYNRITSPQVHRDA-FRKLRLLRSLDLSGNRLHTL 493
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAE--LAPELFADLRAL 252
P N + L + RN+L AL R L G QL L L+ N + L P + DL L
Sbjct: 494 PPGLPRN--VHVLKVKRNELAALARGALAGMAQLRELYLTSNRLRSRALGPRAWVDLAHL 551
Query: 251 ETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAF 72
+ + GN+L +P+ L L L L+NNKIS + N F +++ + L +N+LA
Sbjct: 552 QLLDIAGNQLTEIPEGLPESLEYLY---LQNNKISAVPANAFDSTPNLKGIFLRFNKLAV 608
Query: 71 APDSLYSPLNQLHKLQTLTLAWN 3
+ S +L LQ L + N
Sbjct: 609 G-SVVDSAFRRLKHLQVLDIEGN 630
Score = 55.6 bits (128), Expect = 1e-07
Identities = 54/203 (26%), Positives = 91/203 (44%), Gaps = 5/203 (2%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLT---LKEAVFSNLPALRTLQLDLSSIREL 426
+ N + F L ++E+ + NN LT L F L +L L L +++ +
Sbjct: 293 LKNNKLEKIPPGAFSELSSLRELYLQNNY-LTDEGLDNETFWKLSSLEYLDLSSNNLSRV 351
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAE--LAPELFADLRAL 252
P + L L L +N +R++ +VL L L L N + E + P F L+ L
Sbjct: 352 PAGLPRSLVL--LHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRL 409
Query: 251 ETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAF 72
T + N L+ +P L R + T+ + +N+I+ I F + L+LSYNR+
Sbjct: 410 HTVHLYNNALERVPSGL---PRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRIT- 465
Query: 71 APDSLYSPLNQLHKLQTLTLAWN 3
+P +L L++L L+ N
Sbjct: 466 SPQVHRDAFRKLRLLRSLDLSGN 488
Score = 52.0 bits (119), Expect = 2e-06
Identities = 45/135 (33%), Positives = 61/135 (45%), Gaps = 4/135 (2%)
Frame = -3
Query: 425 PEEFISNSPLRTLSLARNQL--RALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRAL 252
PEE L TL+L N+L R LP T L L L+ N + LAP + AL
Sbjct: 161 PEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLT-LAPRFLPN--AL 217
Query: 251 ETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISM--NTFQGATSIRTLDLSYNRL 78
+ N L + F NL +V L NNK++ + N F G++++ L LS N L
Sbjct: 218 ISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFL 277
Query: 77 AFAPDSLYSPLNQLH 33
P L L +LH
Sbjct: 278 RHVPKHLPPALYKLH 292
Score = 42.7 bits (96), Expect = 0.001
Identities = 45/178 (25%), Positives = 74/178 (41%), Gaps = 4/178 (2%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNN--VPLTLKEAVFSNLPALRTLQLDLSSIREL 426
++ N + E L ++ + + NN L E F +L L L L + +
Sbjct: 150 SLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTLA 209
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAE--LAPELFADLRAL 252
P F+ N+ L ++ A N L + + L S+ L N +A+ L +F +
Sbjct: 210 PR-FLPNA-LISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSSNV 267
Query: 251 ETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
E ++ N L+ +P L L L L+NNK+ I F +S+R L L N L
Sbjct: 268 EVLILSSNFLRHVPKHLPPALYKL---HLKNNKLEKIPPGAFSELSSLRELYLQNNYL 322
>BC028292-1|AAH28292.1| 402|Homo sapiens PODN protein protein.
Length = 402
Score = 76.6 bits (180), Expect = 6e-14
Identities = 61/203 (30%), Positives = 95/203 (46%), Gaps = 5/203 (2%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNN---VPLTLKEAVFSNLPALRTLQLDLSSIREL 426
++ N + E F ++E+ +S N P ++A F L LR+L L + + L
Sbjct: 176 ILHNQITGIGREDFATTYFLEELNLSYNRITSPQVHRDA-FRKLRLLRSLDLSGNRLHTL 234
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAE--LAPELFADLRAL 252
P N + L + RN+L AL R L G QL L L+ N + L P + DL L
Sbjct: 235 PPGLPRN--VHVLKVKRNELAALARGALAGMAQLRELYLTSNRLRSRALGPRAWVDLAHL 292
Query: 251 ETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAF 72
+ + GN+L +P+ L L L L+NNKIS + N F +++ + L +N+LA
Sbjct: 293 QLLDIAGNQLTEIPEGLPESLEYLY---LQNNKISAVPANAFDSTPNLKGIFLRFNKLAV 349
Query: 71 APDSLYSPLNQLHKLQTLTLAWN 3
+ S +L LQ L + N
Sbjct: 350 G-SVVDSAFRRLKHLQVLDIEGN 371
Score = 55.6 bits (128), Expect = 1e-07
Identities = 54/203 (26%), Positives = 91/203 (44%), Gaps = 5/203 (2%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLT---LKEAVFSNLPALRTLQLDLSSIREL 426
+ N + F L ++E+ + NN LT L F L +L L L +++ +
Sbjct: 34 LKNNKLEKIPPGAFSELSSLRELYLQNNY-LTDEGLDNETFWKLSSLEYLDLSSNNLSRV 92
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAE--LAPELFADLRAL 252
P + L L L +N +R++ +VL L L L N + E + P F L+ L
Sbjct: 93 PAGLPRSLVL--LHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRL 150
Query: 251 ETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAF 72
T + N L+ +P L R + T+ + +N+I+ I F + L+LSYNR+
Sbjct: 151 HTVHLYNNALERVPSGL---PRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRIT- 206
Query: 71 APDSLYSPLNQLHKLQTLTLAWN 3
+P +L L++L L+ N
Sbjct: 207 SPQVHRDAFRKLRLLRSLDLSGN 229
>AY358294-1|AAQ88661.1| 642|Homo sapiens EGEE293 protein.
Length = 642
Score = 76.6 bits (180), Expect = 6e-14
Identities = 61/203 (30%), Positives = 95/203 (46%), Gaps = 5/203 (2%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNN---VPLTLKEAVFSNLPALRTLQLDLSSIREL 426
++ N + E F ++E+ +S N P ++A F L LR+L L + + L
Sbjct: 416 ILHNQITGIGREDFATTYFLEELNLSYNRITSPQVHRDA-FRKLRLLRSLDLSGNRLHTL 474
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAE--LAPELFADLRAL 252
P N + L + RN+L AL R L G QL L L+ N + L P + DL L
Sbjct: 475 PPGLPRN--VHVLKVKRNELAALARGALAGMAQLRELYLTSNRLRSRALGPRAWVDLAHL 532
Query: 251 ETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAF 72
+ + GN+L +P+ L L L L+NNKIS + N F +++ + L +N+LA
Sbjct: 533 QLLDIAGNQLTEIPEGLPESLEYLY---LQNNKISAVPANAFDSTPNLKGIFLRFNKLAV 589
Query: 71 APDSLYSPLNQLHKLQTLTLAWN 3
+ S +L LQ L + N
Sbjct: 590 G-SVVDSAFRRLKHLQVLDIEGN 611
Score = 55.6 bits (128), Expect = 1e-07
Identities = 54/203 (26%), Positives = 91/203 (44%), Gaps = 5/203 (2%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLT---LKEAVFSNLPALRTLQLDLSSIREL 426
+ N + F L ++E+ + NN LT L F L +L L L +++ +
Sbjct: 274 LKNNKLEKIPPGAFSELSSLRELYLQNNY-LTDEGLDNETFWKLSSLEYLDLSSNNLSRV 332
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAE--LAPELFADLRAL 252
P + L L L +N +R++ +VL L L L N + E + P F L+ L
Sbjct: 333 PAGLPRSLVL--LHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRL 390
Query: 251 ETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAF 72
T + N L+ +P L R + T+ + +N+I+ I F + L+LSYNR+
Sbjct: 391 HTVHLYNNALERVPSGL---PRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRIT- 446
Query: 71 APDSLYSPLNQLHKLQTLTLAWN 3
+P +L L++L L+ N
Sbjct: 447 SPQVHRDAFRKLRLLRSLDLSGN 469
Score = 52.0 bits (119), Expect = 2e-06
Identities = 45/135 (33%), Positives = 61/135 (45%), Gaps = 4/135 (2%)
Frame = -3
Query: 425 PEEFISNSPLRTLSLARNQL--RALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRAL 252
PEE L TL+L N+L R LP T L L L+ N + LAP + AL
Sbjct: 142 PEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLT-LAPRFLPN--AL 198
Query: 251 ETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISM--NTFQGATSIRTLDLSYNRL 78
+ N L + F NL +V L NNK++ + N F G++++ L LS N L
Sbjct: 199 ISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFL 258
Query: 77 AFAPDSLYSPLNQLH 33
P L L +LH
Sbjct: 259 RHVPKHLPPALYKLH 273
Score = 42.7 bits (96), Expect = 0.001
Identities = 45/178 (25%), Positives = 74/178 (41%), Gaps = 4/178 (2%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNN--VPLTLKEAVFSNLPALRTLQLDLSSIREL 426
++ N + E L ++ + + NN L E F +L L L L + +
Sbjct: 131 SLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTLA 190
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAE--LAPELFADLRAL 252
P F+ N+ L ++ A N L + + L S+ L N +A+ L +F +
Sbjct: 191 PR-FLPNA-LISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSSNV 248
Query: 251 ETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
E ++ N L+ +P L L L L+NNK+ I F +S+R L L N L
Sbjct: 249 EVLILSSNFLRHVPKHLPPALYKL---HLKNNKLEKIPPGAFSELSSLRELYLQNNYL 303
>AY313607-1|AAP79898.1| 613|Homo sapiens podocan protein protein.
Length = 613
Score = 76.2 bits (179), Expect = 8e-14
Identities = 61/203 (30%), Positives = 95/203 (46%), Gaps = 5/203 (2%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNN---VPLTLKEAVFSNLPALRTLQLDLSSIREL 426
++ N + E F ++E+ +S N P ++A F L LR+L L + + L
Sbjct: 387 ILHNQITGIGREDFATTYFLEELNLSYNRITSPQVHRDA-FRKLRLLRSLDLSGNRLHML 445
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAE--LAPELFADLRAL 252
P N + L + RN+L AL R L G QL L L+ N + L P + DL L
Sbjct: 446 PPGLPRN--VHVLKVKRNELAALARGALAGMAQLRELYLTSNRLRSRALGPRAWVDLAHL 503
Query: 251 ETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAF 72
+ + GN+L +P+ L L L L+NNKIS + N F +++ + L +N+LA
Sbjct: 504 QLLDIAGNQLTEIPEGLPESLEYLY---LQNNKISAVPANAFDSTPNLKGIFLRFNKLAV 560
Query: 71 APDSLYSPLNQLHKLQTLTLAWN 3
+ S +L LQ L + N
Sbjct: 561 G-SVVDSAFRRLKHLQVLDIEGN 582
Score = 55.6 bits (128), Expect = 1e-07
Identities = 54/203 (26%), Positives = 91/203 (44%), Gaps = 5/203 (2%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLT---LKEAVFSNLPALRTLQLDLSSIREL 426
+ N + F L ++E+ + NN LT L F L +L L L +++ +
Sbjct: 245 LKNNKLEKIPPGAFSELSSLRELYLQNNY-LTDEGLDNETFWKLSSLEYLDLSSNNLSRV 303
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAE--LAPELFADLRAL 252
P + L L L +N +R++ +VL L L L N + E + P F L+ L
Sbjct: 304 PAGLPRSLVL--LHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRL 361
Query: 251 ETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAF 72
T + N L+ +P L R + T+ + +N+I+ I F + L+LSYNR+
Sbjct: 362 HTVHLYNNALERVPSGL---PRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRIT- 417
Query: 71 APDSLYSPLNQLHKLQTLTLAWN 3
+P +L L++L L+ N
Sbjct: 418 SPQVHRDAFRKLRLLRSLDLSGN 440
Score = 52.0 bits (119), Expect = 2e-06
Identities = 45/135 (33%), Positives = 61/135 (45%), Gaps = 4/135 (2%)
Frame = -3
Query: 425 PEEFISNSPLRTLSLARNQL--RALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRAL 252
PEE L TL+L N+L R LP T L L L+ N + LAP + AL
Sbjct: 113 PEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLT-LAPRFLPN--AL 169
Query: 251 ETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISM--NTFQGATSIRTLDLSYNRL 78
+ N L + F NL +V L NNK++ + N F G++++ L LS N L
Sbjct: 170 ISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFL 229
Query: 77 AFAPDSLYSPLNQLH 33
P L L +LH
Sbjct: 230 RHVPKHLPPALYKLH 244
Score = 42.7 bits (96), Expect = 0.001
Identities = 45/178 (25%), Positives = 74/178 (41%), Gaps = 4/178 (2%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNN--VPLTLKEAVFSNLPALRTLQLDLSSIREL 426
++ N + E L ++ + + NN L E F +L L L L + +
Sbjct: 102 SLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTLA 161
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAE--LAPELFADLRAL 252
P F+ N+ L ++ A N L + + L S+ L N +A+ L +F +
Sbjct: 162 PR-FLPNA-LISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSSNV 219
Query: 251 ETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
E ++ N L+ +P L L L L+NNK+ I F +S+R L L N L
Sbjct: 220 EVLILSSNFLRHVPKHLPPALYKL---HLKNNKLEKIPPGAFSELSSLRELYLQNNYL 274
>AL445183-5|CAH72592.1| 642|Homo sapiens podocan protein.
Length = 642
Score = 75.8 bits (178), Expect = 1e-13
Identities = 61/203 (30%), Positives = 95/203 (46%), Gaps = 5/203 (2%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNN---VPLTLKEAVFSNLPALRTLQLDLSSIREL 426
++ N + E F ++E+ +S N P ++A F L LR+L L + + L
Sbjct: 416 ILHNQITGIGREDFATTYFLEELNLSYNRITSPQVHRDA-FRKLRLLRSLDLSGNRLHTL 474
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAE--LAPELFADLRAL 252
P N + L + RN+L AL R L G QL L L+ N + L P + DL L
Sbjct: 475 PPGLPRN--VHVLKVKRNELAALARGALVGMAQLRELYLTSNRLRSRALGPRAWVDLAHL 532
Query: 251 ETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAF 72
+ + GN+L +P+ L L L L+NNKIS + N F +++ + L +N+LA
Sbjct: 533 QLLDIAGNQLTEIPEGLPESLEYLY---LQNNKISAVPANAFDSTPNLKGIFLRFNKLAV 589
Query: 71 APDSLYSPLNQLHKLQTLTLAWN 3
+ S +L LQ L + N
Sbjct: 590 G-SVVDSAFRRLKHLQVLDIEGN 611
Score = 55.6 bits (128), Expect = 1e-07
Identities = 54/203 (26%), Positives = 91/203 (44%), Gaps = 5/203 (2%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLT---LKEAVFSNLPALRTLQLDLSSIREL 426
+ N + F L ++E+ + NN LT L F L +L L L +++ +
Sbjct: 274 LKNNKLEKIPPGAFSELSSLRELYLQNNY-LTDEGLDNETFWKLSSLEYLDLSSNNLSRV 332
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAE--LAPELFADLRAL 252
P + L L L +N +R++ +VL L L L N + E + P F L+ L
Sbjct: 333 PAGLPRSLVL--LHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRL 390
Query: 251 ETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAF 72
T + N L+ +P L R + T+ + +N+I+ I F + L+LSYNR+
Sbjct: 391 HTVHLYNNALERVPSGL---PRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRIT- 446
Query: 71 APDSLYSPLNQLHKLQTLTLAWN 3
+P +L L++L L+ N
Sbjct: 447 SPQVHRDAFRKLRLLRSLDLSGN 469
Score = 52.0 bits (119), Expect = 2e-06
Identities = 45/135 (33%), Positives = 61/135 (45%), Gaps = 4/135 (2%)
Frame = -3
Query: 425 PEEFISNSPLRTLSLARNQL--RALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRAL 252
PEE L TL+L N+L R LP T L L L+ N + LAP + AL
Sbjct: 142 PEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLT-LAPRFLPN--AL 198
Query: 251 ETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISM--NTFQGATSIRTLDLSYNRL 78
+ N L + F NL +V L NNK++ + N F G++++ L LS N L
Sbjct: 199 ISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFL 258
Query: 77 AFAPDSLYSPLNQLH 33
P L L +LH
Sbjct: 259 RHVPKHLPPALYKLH 273
Score = 42.7 bits (96), Expect = 0.001
Identities = 45/178 (25%), Positives = 74/178 (41%), Gaps = 4/178 (2%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNN--VPLTLKEAVFSNLPALRTLQLDLSSIREL 426
++ N + E L ++ + + NN L E F +L L L L + +
Sbjct: 131 SLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTLA 190
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAE--LAPELFADLRAL 252
P F+ N+ L ++ A N L + + L S+ L N +A+ L +F +
Sbjct: 191 PR-FLPNA-LISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSSNV 248
Query: 251 ETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
E ++ N L+ +P L L L L+NNK+ I F +S+R L L N L
Sbjct: 249 EVLILSSNFLRHVPKHLPPALYKL---HLKNNKLEKIPPGAFSELSSLRELYLQNNYL 303
>AL445183-4|CAH72591.1| 661|Homo sapiens podocan protein.
Length = 661
Score = 75.8 bits (178), Expect = 1e-13
Identities = 61/203 (30%), Positives = 95/203 (46%), Gaps = 5/203 (2%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNN---VPLTLKEAVFSNLPALRTLQLDLSSIREL 426
++ N + E F ++E+ +S N P ++A F L LR+L L + + L
Sbjct: 435 ILHNQITGIGREDFATTYFLEELNLSYNRITSPQVHRDA-FRKLRLLRSLDLSGNRLHTL 493
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAE--LAPELFADLRAL 252
P N + L + RN+L AL R L G QL L L+ N + L P + DL L
Sbjct: 494 PPGLPRN--VHVLKVKRNELAALARGALVGMAQLRELYLTSNRLRSRALGPRAWVDLAHL 551
Query: 251 ETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAF 72
+ + GN+L +P+ L L L L+NNKIS + N F +++ + L +N+LA
Sbjct: 552 QLLDIAGNQLTEIPEGLPESLEYLY---LQNNKISAVPANAFDSTPNLKGIFLRFNKLAV 608
Query: 71 APDSLYSPLNQLHKLQTLTLAWN 3
+ S +L LQ L + N
Sbjct: 609 G-SVVDSAFRRLKHLQVLDIEGN 630
Score = 55.6 bits (128), Expect = 1e-07
Identities = 54/203 (26%), Positives = 91/203 (44%), Gaps = 5/203 (2%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLT---LKEAVFSNLPALRTLQLDLSSIREL 426
+ N + F L ++E+ + NN LT L F L +L L L +++ +
Sbjct: 293 LKNNKLEKIPPGAFSELSSLRELYLQNNY-LTDEGLDNETFWKLSSLEYLDLSSNNLSRV 351
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAE--LAPELFADLRAL 252
P + L L L +N +R++ +VL L L L N + E + P F L+ L
Sbjct: 352 PAGLPRSLVL--LHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRL 409
Query: 251 ETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAF 72
T + N L+ +P L R + T+ + +N+I+ I F + L+LSYNR+
Sbjct: 410 HTVHLYNNALERVPSGL---PRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRIT- 465
Query: 71 APDSLYSPLNQLHKLQTLTLAWN 3
+P +L L++L L+ N
Sbjct: 466 SPQVHRDAFRKLRLLRSLDLSGN 488
Score = 52.0 bits (119), Expect = 2e-06
Identities = 45/135 (33%), Positives = 61/135 (45%), Gaps = 4/135 (2%)
Frame = -3
Query: 425 PEEFISNSPLRTLSLARNQL--RALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRAL 252
PEE L TL+L N+L R LP T L L L+ N + LAP + AL
Sbjct: 161 PEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLT-LAPRFLPN--AL 217
Query: 251 ETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISM--NTFQGATSIRTLDLSYNRL 78
+ N L + F NL +V L NNK++ + N F G++++ L LS N L
Sbjct: 218 ISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFL 277
Query: 77 AFAPDSLYSPLNQLH 33
P L L +LH
Sbjct: 278 RHVPKHLPPALYKLH 292
Score = 42.7 bits (96), Expect = 0.001
Identities = 45/178 (25%), Positives = 74/178 (41%), Gaps = 4/178 (2%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNN--VPLTLKEAVFSNLPALRTLQLDLSSIREL 426
++ N + E L ++ + + NN L E F +L L L L + +
Sbjct: 150 SLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTLA 209
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAE--LAPELFADLRAL 252
P F+ N+ L ++ A N L + + L S+ L N +A+ L +F +
Sbjct: 210 PR-FLPNA-LISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSSNV 267
Query: 251 ETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
E ++ N L+ +P L L L L+NNK+ I F +S+R L L N L
Sbjct: 268 EVLILSSNFLRHVPKHLPPALYKL---HLKNNKLEKIPPGAFSELSSLRELYLQNNYL 322
>DQ084201-1|AAY86708.1| 640|Homo sapiens netrin-G1 ligand splice
variant 3 protein.
Length = 640
Score = 75.4 bits (177), Expect = 1e-13
Identities = 52/200 (26%), Positives = 91/200 (45%), Gaps = 2/200 (1%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ RN R ++ F GL ++ +++ +N T+ F L L+ L L + I +P
Sbjct: 107 LSRNHIRTIEIGAFNGLANLNTLELFDNRLTTISNGAFVYLSKLKELWLRNNPIESIPSY 166
Query: 416 FISNSP-LRTLSLAR-NQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETF 243
+ P LR L L +L + G + L L L+ + E+ P L L L+
Sbjct: 167 AFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREI-PNL-TPLIKLDEL 224
Query: 242 VMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPD 63
+ GN L + F GL +L + + ++I VI N F S+ ++L++N L P
Sbjct: 225 DLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPH 284
Query: 62 SLYSPLNQLHKLQTLTLAWN 3
L++PL+ L ++ W+
Sbjct: 285 DLFTPLHHLERIHLHHNPWS 304
Score = 54.4 bits (125), Expect = 3e-07
Identities = 40/139 (28%), Positives = 64/139 (46%), Gaps = 1/139 (0%)
Frame = -3
Query: 440 SIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADL 261
++RE+P+ +N+ R L+L NQ++ + + + L L LS N + + F L
Sbjct: 66 NLREVPDGISTNT--RLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGL 123
Query: 260 RALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDL-SYN 84
L T + N L + + F L L + LRNN I I F S+R LDL
Sbjct: 124 ANLNTLELFDNRLTTISNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELK 183
Query: 83 RLAFAPDSLYSPLNQLHKL 27
RL++ + + L+ L L
Sbjct: 184 RLSYISEGAFEGLSNLRYL 202
>BC110058-1|AAI10059.1| 518|Homo sapiens leucine rich repeat
transmembrane neuronal 4 protein.
Length = 518
Score = 74.9 bits (176), Expect = 2e-13
Identities = 54/188 (28%), Positives = 87/188 (46%), Gaps = 1/188 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP-EEFI 411
N +D + F+G+ ++E+ +S+N L F +P LR L L + ++ L E+F
Sbjct: 95 NYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFK 154
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L L L N L+ +P V + L L L YN + L+ FA L L+ ++
Sbjct: 155 GLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEH 214
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N+ + + F L NL ++ L+ N+I IS +S+ LDLS N + +
Sbjct: 215 NQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFK 274
Query: 50 PLNQLHKL 27
L L KL
Sbjct: 275 CLPNLQKL 282
Score = 72.5 bits (170), Expect = 1e-12
Identities = 52/188 (27%), Positives = 89/188 (47%), Gaps = 1/188 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
NS + L S F GL+ + + + +N ++ E F + L+ L L + I L +
Sbjct: 71 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 130
Query: 407 NSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
P LR L L+ N+L+ L +G +L L L N++ + +F D R L+ +
Sbjct: 131 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 190
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N L+ L + F+GL L + L +N+ S I+ F ++R++ L +NR+ L
Sbjct: 191 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 250
Query: 50 PLNQLHKL 27
+ LH L
Sbjct: 251 TWSSLHNL 258
Score = 68.9 bits (161), Expect = 1e-11
Identities = 51/179 (28%), Positives = 82/179 (45%), Gaps = 1/179 (0%)
Frame = -3
Query: 536 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRA 360
Q + + N LK F+ L L L LD + I + E+ F L+ L L+ N++
Sbjct: 64 QGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITY 123
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
L L +L LSYN + L E F LR L + N L+ +P +F RNL
Sbjct: 124 LHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNL 183
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
+ L N++ +S N F G ++ L L +N+ + ++ +L L+++ L WN
Sbjct: 184 DFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFS---KINFAHFPRLFNLRSIYLQWN 239
Score = 61.3 bits (142), Expect = 3e-09
Identities = 45/171 (26%), Positives = 79/171 (46%), Gaps = 1/171 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP-EEFI 411
N YL ++ F + +++ + +S N TL+ F L L L L +S++ +P F
Sbjct: 119 NKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQ 178
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L L L N+LR+L R+ G +L L L +N +++ F L L + +
Sbjct: 179 DCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQW 238
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
N ++ + L +L + L N I I TF+ +++ L+L N+L
Sbjct: 239 NRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKL 289
Score = 58.4 bits (135), Expect = 2e-08
Identities = 45/169 (26%), Positives = 76/169 (44%), Gaps = 1/169 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FI 411
N + L SE F+GL + + + +N T+ VF + L L L + +R L F
Sbjct: 143 NKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFA 202
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L+ L L NQ + + L S+ L +N + ++ L +L + G
Sbjct: 203 GLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSG 262
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
N++Q + F L NL ++L +NK++ IS T S+ ++ LS N
Sbjct: 263 NDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGN 311
>BC099738-1|AAH99738.1| 518|Homo sapiens leucine rich repeat
transmembrane neuronal 4 protein.
Length = 518
Score = 74.9 bits (176), Expect = 2e-13
Identities = 54/188 (28%), Positives = 87/188 (46%), Gaps = 1/188 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP-EEFI 411
N +D + F+G+ ++E+ +S+N L F +P LR L L + ++ L E+F
Sbjct: 95 NYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFK 154
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L L L N L+ +P V + L L L YN + L+ FA L L+ ++
Sbjct: 155 GLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEH 214
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N+ + + F L NL ++ L+ N+I IS +S+ LDLS N + +
Sbjct: 215 NQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFK 274
Query: 50 PLNQLHKL 27
L L KL
Sbjct: 275 CLPNLQKL 282
Score = 72.5 bits (170), Expect = 1e-12
Identities = 52/188 (27%), Positives = 89/188 (47%), Gaps = 1/188 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
NS + L S F GL+ + + + +N ++ E F + L+ L L + I L +
Sbjct: 71 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 130
Query: 407 NSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
P LR L L+ N+L+ L +G +L L L N++ + +F D R L+ +
Sbjct: 131 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 190
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N L+ L + F+GL L + L +N+ S I+ F ++R++ L +NR+ L
Sbjct: 191 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 250
Query: 50 PLNQLHKL 27
+ LH L
Sbjct: 251 TWSSLHNL 258
Score = 68.9 bits (161), Expect = 1e-11
Identities = 51/179 (28%), Positives = 82/179 (45%), Gaps = 1/179 (0%)
Frame = -3
Query: 536 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRA 360
Q + + N LK F+ L L L LD + I + E+ F L+ L L+ N++
Sbjct: 64 QGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITY 123
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
L L +L LSYN + L E F LR L + N L+ +P +F RNL
Sbjct: 124 LHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNL 183
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
+ L N++ +S N F G ++ L L +N+ + ++ +L L+++ L WN
Sbjct: 184 DFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFS---KINFAHFPRLFNLRSIYLQWN 239
Score = 61.3 bits (142), Expect = 3e-09
Identities = 45/171 (26%), Positives = 79/171 (46%), Gaps = 1/171 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP-EEFI 411
N YL ++ F + +++ + +S N TL+ F L L L L +S++ +P F
Sbjct: 119 NKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQ 178
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L L L N+LR+L R+ G +L L L +N +++ F L L + +
Sbjct: 179 DCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQW 238
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
N ++ + L +L + L N I I TF+ +++ L+L N+L
Sbjct: 239 NRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKL 289
Score = 58.4 bits (135), Expect = 2e-08
Identities = 45/169 (26%), Positives = 76/169 (44%), Gaps = 1/169 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FI 411
N + L SE F+GL + + + +N T+ VF + L L L + +R L F
Sbjct: 143 NKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFA 202
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L+ L L NQ + + L S+ L +N + ++ L +L + G
Sbjct: 203 GLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSG 262
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
N++Q + F L NL ++L +NK++ IS T S+ ++ LS N
Sbjct: 263 NDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGN 311
>BC098301-1|AAH98301.1| 519|Homo sapiens LRRTM4 protein protein.
Length = 519
Score = 74.9 bits (176), Expect = 2e-13
Identities = 54/188 (28%), Positives = 87/188 (46%), Gaps = 1/188 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP-EEFI 411
N +D + F+G+ ++E+ +S+N L F +P LR L L + ++ L E+F
Sbjct: 96 NYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFK 155
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L L L N L+ +P V + L L L YN + L+ FA L L+ ++
Sbjct: 156 GLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEH 215
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N+ + + F L NL ++ L+ N+I IS +S+ LDLS N + +
Sbjct: 216 NQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFK 275
Query: 50 PLNQLHKL 27
L L KL
Sbjct: 276 CLPNLQKL 283
Score = 72.5 bits (170), Expect = 1e-12
Identities = 52/188 (27%), Positives = 89/188 (47%), Gaps = 1/188 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
NS + L S F GL+ + + + +N ++ E F + L+ L L + I L +
Sbjct: 72 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 131
Query: 407 NSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
P LR L L+ N+L+ L +G +L L L N++ + +F D R L+ +
Sbjct: 132 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 191
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N L+ L + F+GL L + L +N+ S I+ F ++R++ L +NR+ L
Sbjct: 192 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 251
Query: 50 PLNQLHKL 27
+ LH L
Sbjct: 252 TWSSLHNL 259
Score = 68.9 bits (161), Expect = 1e-11
Identities = 51/179 (28%), Positives = 82/179 (45%), Gaps = 1/179 (0%)
Frame = -3
Query: 536 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRA 360
Q + + N LK F+ L L L LD + I + E+ F L+ L L+ N++
Sbjct: 65 QGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITY 124
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
L L +L LSYN + L E F LR L + N L+ +P +F RNL
Sbjct: 125 LHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNL 184
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
+ L N++ +S N F G ++ L L +N+ + ++ +L L+++ L WN
Sbjct: 185 DFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFS---KINFAHFPRLFNLRSIYLQWN 240
Score = 61.3 bits (142), Expect = 3e-09
Identities = 45/171 (26%), Positives = 79/171 (46%), Gaps = 1/171 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP-EEFI 411
N YL ++ F + +++ + +S N TL+ F L L L L +S++ +P F
Sbjct: 120 NKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQ 179
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L L L N+LR+L R+ G +L L L +N +++ F L L + +
Sbjct: 180 DCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQW 239
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
N ++ + L +L + L N I I TF+ +++ L+L N+L
Sbjct: 240 NRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKL 290
Score = 58.4 bits (135), Expect = 2e-08
Identities = 45/169 (26%), Positives = 76/169 (44%), Gaps = 1/169 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FI 411
N + L SE F+GL + + + +N T+ VF + L L L + +R L F
Sbjct: 144 NKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFA 203
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L+ L L NQ + + L S+ L +N + ++ L +L + G
Sbjct: 204 GLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSG 263
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
N++Q + F L NL ++L +NK++ IS T S+ ++ LS N
Sbjct: 264 NDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGN 312
>BC098267-1|AAH98267.1| 519|Homo sapiens LRRTM4 protein protein.
Length = 519
Score = 74.9 bits (176), Expect = 2e-13
Identities = 54/188 (28%), Positives = 87/188 (46%), Gaps = 1/188 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP-EEFI 411
N +D + F+G+ ++E+ +S+N L F +P LR L L + ++ L E+F
Sbjct: 96 NYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFK 155
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L L L N L+ +P V + L L L YN + L+ FA L L+ ++
Sbjct: 156 GLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEH 215
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N+ + + F L NL ++ L+ N+I IS +S+ LDLS N + +
Sbjct: 216 NQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFK 275
Query: 50 PLNQLHKL 27
L L KL
Sbjct: 276 CLPNLQKL 283
Score = 72.5 bits (170), Expect = 1e-12
Identities = 52/188 (27%), Positives = 89/188 (47%), Gaps = 1/188 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
NS + L S F GL+ + + + +N ++ E F + L+ L L + I L +
Sbjct: 72 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 131
Query: 407 NSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
P LR L L+ N+L+ L +G +L L L N++ + +F D R L+ +
Sbjct: 132 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 191
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N L+ L + F+GL L + L +N+ S I+ F ++R++ L +NR+ L
Sbjct: 192 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 251
Query: 50 PLNQLHKL 27
+ LH L
Sbjct: 252 TWSSLHNL 259
Score = 68.9 bits (161), Expect = 1e-11
Identities = 51/179 (28%), Positives = 82/179 (45%), Gaps = 1/179 (0%)
Frame = -3
Query: 536 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRA 360
Q + + N LK F+ L L L LD + I + E+ F L+ L L+ N++
Sbjct: 65 QGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITY 124
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
L L +L LSYN + L E F LR L + N L+ +P +F RNL
Sbjct: 125 LHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNL 184
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
+ L N++ +S N F G ++ L L +N+ + ++ +L L+++ L WN
Sbjct: 185 DFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFS---KINFAHFPRLFNLRSIYLQWN 240
Score = 61.3 bits (142), Expect = 3e-09
Identities = 45/171 (26%), Positives = 79/171 (46%), Gaps = 1/171 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP-EEFI 411
N YL ++ F + +++ + +S N TL+ F L L L L +S++ +P F
Sbjct: 120 NKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQ 179
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L L L N+LR+L R+ G +L L L +N +++ F L L + +
Sbjct: 180 DCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQW 239
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
N ++ + L +L + L N I I TF+ +++ L+L N+L
Sbjct: 240 NRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKL 290
Score = 58.4 bits (135), Expect = 2e-08
Identities = 45/169 (26%), Positives = 76/169 (44%), Gaps = 1/169 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FI 411
N + L SE F+GL + + + +N T+ VF + L L L + +R L F
Sbjct: 144 NKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFA 203
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L+ L L NQ + + L S+ L +N + ++ L +L + G
Sbjct: 204 GLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSG 263
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
N++Q + F L NL ++L +NK++ IS T S+ ++ LS N
Sbjct: 264 NDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGN 312
>AY358324-1|AAQ88690.1| 590|Homo sapiens GFHL3075 protein.
Length = 590
Score = 74.9 bits (176), Expect = 2e-13
Identities = 54/188 (28%), Positives = 87/188 (46%), Gaps = 1/188 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP-EEFI 411
N +D + F+G+ ++E+ +S+N L F +P LR L L + ++ L E+F
Sbjct: 95 NYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFK 154
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L L L N L+ +P V + L L L YN + L+ FA L L+ ++
Sbjct: 155 GLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEH 214
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N+ + + F L NL ++ L+ N+I IS +S+ LDLS N + +
Sbjct: 215 NQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFK 274
Query: 50 PLNQLHKL 27
L L KL
Sbjct: 275 CLPNLQKL 282
Score = 72.5 bits (170), Expect = 1e-12
Identities = 52/188 (27%), Positives = 89/188 (47%), Gaps = 1/188 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
NS + L S F GL+ + + + +N ++ E F + L+ L L + I L +
Sbjct: 71 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 130
Query: 407 NSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
P LR L L+ N+L+ L +G +L L L N++ + +F D R L+ +
Sbjct: 131 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 190
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N L+ L + F+GL L + L +N+ S I+ F ++R++ L +NR+ L
Sbjct: 191 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 250
Query: 50 PLNQLHKL 27
+ LH L
Sbjct: 251 TWSSLHNL 258
Score = 68.9 bits (161), Expect = 1e-11
Identities = 51/179 (28%), Positives = 82/179 (45%), Gaps = 1/179 (0%)
Frame = -3
Query: 536 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRA 360
Q + + N LK F+ L L L LD + I + E+ F L+ L L+ N++
Sbjct: 64 QGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITY 123
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
L L +L LSYN + L E F LR L + N L+ +P +F RNL
Sbjct: 124 LHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNL 183
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
+ L N++ +S N F G ++ L L +N+ + ++ +L L+++ L WN
Sbjct: 184 DFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFS---KINFAHFPRLFNLRSIYLQWN 239
Score = 61.3 bits (142), Expect = 3e-09
Identities = 45/171 (26%), Positives = 79/171 (46%), Gaps = 1/171 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP-EEFI 411
N YL ++ F + +++ + +S N TL+ F L L L L +S++ +P F
Sbjct: 119 NKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQ 178
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L L L N+LR+L R+ G +L L L +N +++ F L L + +
Sbjct: 179 DCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQW 238
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
N ++ + L +L + L N I I TF+ +++ L+L N+L
Sbjct: 239 NRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKL 289
Score = 58.4 bits (135), Expect = 2e-08
Identities = 45/169 (26%), Positives = 76/169 (44%), Gaps = 1/169 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FI 411
N + L SE F+GL + + + +N T+ VF + L L L + +R L F
Sbjct: 143 NKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFA 202
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L+ L L NQ + + L S+ L +N + ++ L +L + G
Sbjct: 203 GLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSG 262
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
N++Q + F L NL ++L +NK++ IS T S+ ++ LS N
Sbjct: 263 NDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGN 311
>AY182030-1|AAO67551.1| 518|Homo sapiens leucine-rich repeat
transmembrane neuronal 4 protein protein.
Length = 518
Score = 74.9 bits (176), Expect = 2e-13
Identities = 54/188 (28%), Positives = 87/188 (46%), Gaps = 1/188 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP-EEFI 411
N +D + F+G+ ++E+ +S+N L F +P LR L L + ++ L E+F
Sbjct: 95 NYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFK 154
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L L L N L+ +P V + L L L YN + L+ FA L L+ ++
Sbjct: 155 GLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEH 214
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N+ + + F L NL ++ L+ N+I IS +S+ LDLS N + +
Sbjct: 215 NQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFK 274
Query: 50 PLNQLHKL 27
L L KL
Sbjct: 275 CLPNLQKL 282
Score = 72.5 bits (170), Expect = 1e-12
Identities = 52/188 (27%), Positives = 89/188 (47%), Gaps = 1/188 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
NS + L S F GL+ + + + +N ++ E F + L+ L L + I L +
Sbjct: 71 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 130
Query: 407 NSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
P LR L L+ N+L+ L +G +L L L N++ + +F D R L+ +
Sbjct: 131 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 190
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N L+ L + F+GL L + L +N+ S I+ F ++R++ L +NR+ L
Sbjct: 191 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 250
Query: 50 PLNQLHKL 27
+ LH L
Sbjct: 251 TWSSLHNL 258
Score = 68.9 bits (161), Expect = 1e-11
Identities = 51/179 (28%), Positives = 82/179 (45%), Gaps = 1/179 (0%)
Frame = -3
Query: 536 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRA 360
Q + + N LK F+ L L L LD + I + E+ F L+ L L+ N++
Sbjct: 64 QGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITY 123
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
L L +L LSYN + L E F LR L + N L+ +P +F RNL
Sbjct: 124 LHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNL 183
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
+ L N++ +S N F G ++ L L +N+ + ++ +L L+++ L WN
Sbjct: 184 DFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFS---KINFAHFPRLFNLRSIYLQWN 239
Score = 61.3 bits (142), Expect = 3e-09
Identities = 45/171 (26%), Positives = 79/171 (46%), Gaps = 1/171 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP-EEFI 411
N YL ++ F + +++ + +S N TL+ F L L L L +S++ +P F
Sbjct: 119 NKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQ 178
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L L L N+LR+L R+ G +L L L +N +++ F L L + +
Sbjct: 179 DCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQW 238
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
N ++ + L +L + L N I I TF+ +++ L+L N+L
Sbjct: 239 NRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKL 289
Score = 58.4 bits (135), Expect = 2e-08
Identities = 45/169 (26%), Positives = 76/169 (44%), Gaps = 1/169 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FI 411
N + L SE F+GL + + + +N T+ VF + L L L + +R L F
Sbjct: 143 NKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFA 202
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L+ L L NQ + + L S+ L +N + ++ L +L + G
Sbjct: 203 GLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSG 262
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
N++Q + F L NL ++L +NK++ IS T S+ ++ LS N
Sbjct: 263 NDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGN 311
>AK126961-1|BAC86764.1| 518|Homo sapiens protein ( Homo sapiens
cDNA FLJ45014 fis, clone BRAWH3014609. ).
Length = 518
Score = 74.9 bits (176), Expect = 2e-13
Identities = 54/188 (28%), Positives = 87/188 (46%), Gaps = 1/188 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP-EEFI 411
N +D + F+G+ ++E+ +S+N L F +P LR L L + ++ L E+F
Sbjct: 95 NYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFK 154
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L L L N L+ +P V + L L L YN + L+ FA L L+ ++
Sbjct: 155 GLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEH 214
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N+ + + F L NL ++ L+ N+I IS +S+ LDLS N + +
Sbjct: 215 NQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFK 274
Query: 50 PLNQLHKL 27
L L KL
Sbjct: 275 CLPNLQKL 282
Score = 72.5 bits (170), Expect = 1e-12
Identities = 52/188 (27%), Positives = 89/188 (47%), Gaps = 1/188 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
NS + L S F GL+ + + + +N ++ E F + L+ L L + I L +
Sbjct: 71 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 130
Query: 407 NSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
P LR L L+ N+L+ L +G +L L L N++ + +F D R L+ +
Sbjct: 131 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 190
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N L+ L + F+GL L + L +N+ S I+ F ++R++ L +NR+ L
Sbjct: 191 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 250
Query: 50 PLNQLHKL 27
+ LH L
Sbjct: 251 TWSSLHNL 258
Score = 70.1 bits (164), Expect = 6e-12
Identities = 56/197 (28%), Positives = 91/197 (46%), Gaps = 6/197 (3%)
Frame = -3
Query: 575 YLDSEIFRGL-DHI----QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-F 414
Y +S F G+ ++I Q + + N LK F+ L L L LD + I + E+ F
Sbjct: 46 YCESHAFAGIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAF 105
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
L+ L L+ N++ L L +L LSYN + L E F LR L +
Sbjct: 106 QGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLR 165
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
N L+ +P +F RNL + L N++ +S N F G ++ L L +N+ + +
Sbjct: 166 SNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFS---KINF 222
Query: 53 SPLNQLHKLQTLTLAWN 3
+ +L L+++ L WN
Sbjct: 223 AHFPRLFNLRSIYLQWN 239
Score = 61.3 bits (142), Expect = 3e-09
Identities = 45/171 (26%), Positives = 79/171 (46%), Gaps = 1/171 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP-EEFI 411
N YL ++ F + +++ + +S N TL+ F L L L L +S++ +P F
Sbjct: 119 NKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQ 178
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L L L N+LR+L R+ G +L L L +N +++ F L L + +
Sbjct: 179 DCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQW 238
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
N ++ + L +L + L N I I TF+ +++ L+L N+L
Sbjct: 239 NRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKL 289
Score = 58.4 bits (135), Expect = 2e-08
Identities = 45/169 (26%), Positives = 76/169 (44%), Gaps = 1/169 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FI 411
N + L SE F+GL + + + +N T+ VF + L L L + +R L F
Sbjct: 143 NKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFA 202
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L+ L L NQ + + L S+ L +N + ++ L +L + G
Sbjct: 203 GLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSG 262
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
N++Q + F L NL ++L +NK++ IS T S+ ++ LS N
Sbjct: 263 NDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGN 311
>AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat
protein LRIG1 protein.
Length = 1093
Score = 73.7 bits (173), Expect = 4e-13
Identities = 51/189 (26%), Positives = 91/189 (48%), Gaps = 1/189 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N +D F L ++QE+ +S N + A F +LP L+ + L+ + + +P +
Sbjct: 78 NKLSEIDPAGFEDLPNLQEVNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGAA 137
Query: 407 NSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 228
+S + +L L N++R++ S L+ L L LS N + E+ F ++ + GN
Sbjct: 138 SSHVVSLFLQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGN 197
Query: 227 ELQVLPDSLFSGL-RNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
+ L F GL R+L T+ L N+I+ + + F+ + LDL+ NR+ +
Sbjct: 198 RIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAFK-LPRLTQLDLNRNRIRLIEGLTFQ 256
Query: 50 PLNQLHKLQ 24
LN L L+
Sbjct: 257 GLNSLEVLK 265
Score = 70.1 bits (164), Expect = 6e-12
Identities = 52/199 (26%), Positives = 92/199 (46%), Gaps = 1/199 (0%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE- 420
+ +N L F+ L + ++ ++ N ++ F L +L L+L ++I +L +
Sbjct: 219 LSKNRITQLPVRAFK-LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDG 277
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
F S + L L N L + L G T L L LS N++A + + ++ + L V
Sbjct: 278 AFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELV 337
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
+ N L L + + L +L+ + L +N IS I+ F+G S+R LDL +N ++ +
Sbjct: 338 LSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIED 397
Query: 59 LYSPLNQLHKLQTLTLAWN 3
+ L L L L N
Sbjct: 398 TSGAFSGLDSLSKLNLGGN 416
Score = 60.5 bits (140), Expect = 4e-09
Identities = 47/173 (27%), Positives = 80/173 (46%), Gaps = 4/173 (2%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ RN+ L F GL + + + N + + L AL L L +SI + +
Sbjct: 266 LQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRK 325
Query: 416 FISN-SPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
S L L L+ N L L L + L+ L LS+N+++ +A F LR+L
Sbjct: 326 GWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLD 385
Query: 239 MDGNELQ-VLPDS--LFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLS 90
+D NE+ + D+ FSGL +L+ ++L N I + + F +++ L +S
Sbjct: 386 LDHNEISGTIEDTSGAFSGLDSLSKLNLGGNAIRSVQFDAFVKMKNLKELHIS 438
Score = 58.4 bits (135), Expect = 2e-08
Identities = 46/173 (26%), Positives = 75/173 (43%), Gaps = 1/173 (0%)
Frame = -3
Query: 539 IQEIKISNNVPLTLKEAVFSNLP-ALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLR 363
I+E+ ++ N TL+ F L +L TL+L + I +LP L L L RN++R
Sbjct: 189 IKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAFKLPRLTQLDLNRNRIR 248
Query: 362 ALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRN 183
+ +G L L L N +++L F L + ++ N L + GL
Sbjct: 249 LIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTA 308
Query: 182 LTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
L + L NN I+ I + + L LS+N L + + L+ L L+
Sbjct: 309 LHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLR 361
Score = 56.0 bits (129), Expect = 1e-07
Identities = 32/106 (30%), Positives = 58/106 (54%)
Frame = -3
Query: 395 RTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 216
R+L+L+ N+L + + L + LSYN ++E+ P F DL L+ ++ NEL
Sbjct: 71 RSLNLSYNKLSEIDPAGFEDLPNLQEVNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTA 130
Query: 215 LPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
+P SL + ++ ++ L++NKI + + + S+ LDLS N +
Sbjct: 131 VP-SLGAASSHVVSLFLQHNKIRSVEGSQLKAYLSLEVLDLSLNNI 175
Score = 31.1 bits (67), Expect = 3.1
Identities = 21/69 (30%), Positives = 36/69 (52%)
Frame = -3
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
G L LP L S R+L +L NK+S I F+ +++ ++LSYN+L+ + +
Sbjct: 56 GRGLAALPGDLPSWTRSL---NLSYNKLSEIDPAGFEDLPNLQEVNLSYNKLSEIDPAGF 112
Query: 53 SPLNQLHKL 27
L L ++
Sbjct: 113 EDLPNLQEV 121
>BC111013-1|AAI11014.1| 428|Homo sapiens immunoglobulin superfamily
containing leucine-rich repeat protein.
Length = 428
Score = 73.3 bits (172), Expect = 6e-13
Identities = 45/139 (32%), Positives = 73/139 (52%), Gaps = 2/139 (1%)
Frame = -3
Query: 494 EAVFSNLPA-LRTLQLDLSSIRELPEEFISNSPL-RTLSLARNQLRALPRSVLRGQTQLT 321
E+V PA + TL L + + LPE PL ++L LA N++R + L + L
Sbjct: 42 ESVPPGFPANVTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLK 101
Query: 320 SLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVI 141
SL LS+N +++ A +L AL+ MD NEL +P F LR L ++ L +N++ +
Sbjct: 102 SLDLSHNLISDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTL 161
Query: 140 SMNTFQGATSIRTLDLSYN 84
+ TF T++ L ++ N
Sbjct: 162 AEGTFTPLTALSHLQINEN 180
Score = 62.9 bits (146), Expect = 8e-10
Identities = 42/141 (29%), Positives = 74/141 (52%), Gaps = 3/141 (2%)
Frame = -3
Query: 437 IRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 258
+ +P F +N + TLSL+ N+L LP R L SL L++N + +A A L
Sbjct: 41 LESVPPGFPAN--VTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLS 98
Query: 257 ALETFVMDGNELQVLPDSLFSGLRNLTTVSLR---NNKISVISMNTFQGATSIRTLDLSY 87
L++ + N ++ D +S L NL+ + L +N+++ I + F+ ++R+L L++
Sbjct: 99 HLKSLDLSHN---LISDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNH 155
Query: 86 NRLAFAPDSLYSPLNQLHKLQ 24
NRL + ++PL L LQ
Sbjct: 156 NRLHTLAEGTFTPLTALSHLQ 176
>BC022478-1|AAH22478.1| 428|Homo sapiens immunoglobulin superfamily
containing leucine-rich repeat protein.
Length = 428
Score = 73.3 bits (172), Expect = 6e-13
Identities = 45/139 (32%), Positives = 73/139 (52%), Gaps = 2/139 (1%)
Frame = -3
Query: 494 EAVFSNLPA-LRTLQLDLSSIRELPEEFISNSPL-RTLSLARNQLRALPRSVLRGQTQLT 321
E+V PA + TL L + + LPE PL ++L LA N++R + L + L
Sbjct: 42 ESVPPGFPANVTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLK 101
Query: 320 SLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVI 141
SL LS+N +++ A +L AL+ MD NEL +P F LR L ++ L +N++ +
Sbjct: 102 SLDLSHNLISDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTL 161
Query: 140 SMNTFQGATSIRTLDLSYN 84
+ TF T++ L ++ N
Sbjct: 162 AEGTFTPLTALSHLQINEN 180
Score = 62.9 bits (146), Expect = 8e-10
Identities = 42/141 (29%), Positives = 74/141 (52%), Gaps = 3/141 (2%)
Frame = -3
Query: 437 IRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 258
+ +P F +N + TLSL+ N+L LP R L SL L++N + +A A L
Sbjct: 41 LESVPPGFPAN--VTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLS 98
Query: 257 ALETFVMDGNELQVLPDSLFSGLRNLTTVSLR---NNKISVISMNTFQGATSIRTLDLSY 87
L++ + N ++ D +S L NL+ + L +N+++ I + F+ ++R+L L++
Sbjct: 99 HLKSLDLSHN---LISDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNH 155
Query: 86 NRLAFAPDSLYSPLNQLHKLQ 24
NRL + ++PL L LQ
Sbjct: 156 NRLHTLAEGTFTPLTALSHLQ 176
>AY358871-1|AAQ89230.1| 428|Homo sapiens ISLR protein.
Length = 428
Score = 73.3 bits (172), Expect = 6e-13
Identities = 45/139 (32%), Positives = 73/139 (52%), Gaps = 2/139 (1%)
Frame = -3
Query: 494 EAVFSNLPA-LRTLQLDLSSIRELPEEFISNSPL-RTLSLARNQLRALPRSVLRGQTQLT 321
E+V PA + TL L + + LPE PL ++L LA N++R + L + L
Sbjct: 42 ESVPPGFPANVTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLK 101
Query: 320 SLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVI 141
SL LS+N +++ A +L AL+ MD NEL +P F LR L ++ L +N++ +
Sbjct: 102 SLDLSHNLISDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTL 161
Query: 140 SMNTFQGATSIRTLDLSYN 84
+ TF T++ L ++ N
Sbjct: 162 AEGTFTPLTALSHLQINEN 180
Score = 62.9 bits (146), Expect = 8e-10
Identities = 42/141 (29%), Positives = 74/141 (52%), Gaps = 3/141 (2%)
Frame = -3
Query: 437 IRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 258
+ +P F +N + TLSL+ N+L LP R L SL L++N + +A A L
Sbjct: 41 LESVPPGFPAN--VTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLS 98
Query: 257 ALETFVMDGNELQVLPDSLFSGLRNLTTVSLR---NNKISVISMNTFQGATSIRTLDLSY 87
L++ + N ++ D +S L NL+ + L +N+++ I + F+ ++R+L L++
Sbjct: 99 HLKSLDLSHN---LISDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNH 155
Query: 86 NRLAFAPDSLYSPLNQLHKLQ 24
NRL + ++PL L LQ
Sbjct: 156 NRLHTLAEGTFTPLTALSHLQ 176
>AK223267-1|BAD96987.1| 428|Homo sapiens immunoglobulin superfamily
containing leucine-rich repeat variant protein.
Length = 428
Score = 73.3 bits (172), Expect = 6e-13
Identities = 45/139 (32%), Positives = 73/139 (52%), Gaps = 2/139 (1%)
Frame = -3
Query: 494 EAVFSNLPA-LRTLQLDLSSIRELPEEFISNSPL-RTLSLARNQLRALPRSVLRGQTQLT 321
E+V PA + TL L + + LPE PL ++L LA N++R + L + L
Sbjct: 42 ESVPPGFPANVTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLK 101
Query: 320 SLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVI 141
SL LS+N +++ A +L AL+ MD NEL +P F LR L ++ L +N++ +
Sbjct: 102 SLDLSHNLISDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTL 161
Query: 140 SMNTFQGATSIRTLDLSYN 84
+ TF T++ L ++ N
Sbjct: 162 AEGTFTPLTALSHLQINEN 180
Score = 62.9 bits (146), Expect = 8e-10
Identities = 42/141 (29%), Positives = 74/141 (52%), Gaps = 3/141 (2%)
Frame = -3
Query: 437 IRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 258
+ +P F +N + TLSL+ N+L LP R L SL L++N + +A A L
Sbjct: 41 LESVPPGFPAN--VTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLS 98
Query: 257 ALETFVMDGNELQVLPDSLFSGLRNLTTVSLR---NNKISVISMNTFQGATSIRTLDLSY 87
L++ + N ++ D +S L NL+ + L +N+++ I + F+ ++R+L L++
Sbjct: 99 HLKSLDLSHN---LISDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNH 155
Query: 86 NRLAFAPDSLYSPLNQLHKLQ 24
NRL + ++PL L LQ
Sbjct: 156 NRLHTLAEGTFTPLTALSHLQ 176
>AB024537-1|BAA85971.1| 428|Homo sapiens ISLR protein.
Length = 428
Score = 73.3 bits (172), Expect = 6e-13
Identities = 45/139 (32%), Positives = 73/139 (52%), Gaps = 2/139 (1%)
Frame = -3
Query: 494 EAVFSNLPA-LRTLQLDLSSIRELPEEFISNSPL-RTLSLARNQLRALPRSVLRGQTQLT 321
E+V PA + TL L + + LPE PL ++L LA N++R + L + L
Sbjct: 42 ESVPPGFPANVTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLK 101
Query: 320 SLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVI 141
SL LS+N +++ A +L AL+ MD NEL +P F LR L ++ L +N++ +
Sbjct: 102 SLDLSHNLISDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTL 161
Query: 140 SMNTFQGATSIRTLDLSYN 84
+ TF T++ L ++ N
Sbjct: 162 AEGTFTPLTALSHLQINEN 180
Score = 62.9 bits (146), Expect = 8e-10
Identities = 42/141 (29%), Positives = 74/141 (52%), Gaps = 3/141 (2%)
Frame = -3
Query: 437 IRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 258
+ +P F +N + TLSL+ N+L LP R L SL L++N + +A A L
Sbjct: 41 LESVPPGFPAN--VTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLS 98
Query: 257 ALETFVMDGNELQVLPDSLFSGLRNLTTVSLR---NNKISVISMNTFQGATSIRTLDLSY 87
L++ + N ++ D +S L NL+ + L +N+++ I + F+ ++R+L L++
Sbjct: 99 HLKSLDLSHN---LISDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNH 155
Query: 86 NRLAFAPDSLYSPLNQLHKLQ 24
NRL + ++PL L LQ
Sbjct: 156 NRLHTLAEGTFTPLTALSHLQ 176
>AB024536-1|BAA85970.1| 428|Homo sapiens ISLR protein.
Length = 428
Score = 73.3 bits (172), Expect = 6e-13
Identities = 45/139 (32%), Positives = 73/139 (52%), Gaps = 2/139 (1%)
Frame = -3
Query: 494 EAVFSNLPA-LRTLQLDLSSIRELPEEFISNSPL-RTLSLARNQLRALPRSVLRGQTQLT 321
E+V PA + TL L + + LPE PL ++L LA N++R + L + L
Sbjct: 42 ESVPPGFPANVTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLK 101
Query: 320 SLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVI 141
SL LS+N +++ A +L AL+ MD NEL +P F LR L ++ L +N++ +
Sbjct: 102 SLDLSHNLISDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTL 161
Query: 140 SMNTFQGATSIRTLDLSYN 84
+ TF T++ L ++ N
Sbjct: 162 AEGTFTPLTALSHLQINEN 180
Score = 62.9 bits (146), Expect = 8e-10
Identities = 42/141 (29%), Positives = 74/141 (52%), Gaps = 3/141 (2%)
Frame = -3
Query: 437 IRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 258
+ +P F +N + TLSL+ N+L LP R L SL L++N + +A A L
Sbjct: 41 LESVPPGFPAN--VTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLS 98
Query: 257 ALETFVMDGNELQVLPDSLFSGLRNLTTVSLR---NNKISVISMNTFQGATSIRTLDLSY 87
L++ + N ++ D +S L NL+ + L +N+++ I + F+ ++R+L L++
Sbjct: 99 HLKSLDLSHN---LISDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNH 155
Query: 86 NRLAFAPDSLYSPLNQLHKLQ 24
NRL + ++PL L LQ
Sbjct: 156 NRLHTLAEGTFTPLTALSHLQ 176
>AB003184-1|BAA22848.1| 428|Homo sapiens ISLR protein.
Length = 428
Score = 73.3 bits (172), Expect = 6e-13
Identities = 45/139 (32%), Positives = 73/139 (52%), Gaps = 2/139 (1%)
Frame = -3
Query: 494 EAVFSNLPA-LRTLQLDLSSIRELPEEFISNSPL-RTLSLARNQLRALPRSVLRGQTQLT 321
E+V PA + TL L + + LPE PL ++L LA N++R + L + L
Sbjct: 42 ESVPPGFPANVTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLK 101
Query: 320 SLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVI 141
SL LS+N +++ A +L AL+ MD NEL +P F LR L ++ L +N++ +
Sbjct: 102 SLDLSHNLISDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTL 161
Query: 140 SMNTFQGATSIRTLDLSYN 84
+ TF T++ L ++ N
Sbjct: 162 AEGTFTPLTALSHLQINEN 180
Score = 62.9 bits (146), Expect = 8e-10
Identities = 42/141 (29%), Positives = 74/141 (52%), Gaps = 3/141 (2%)
Frame = -3
Query: 437 IRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 258
+ +P F +N + TLSL+ N+L LP R L SL L++N + +A A L
Sbjct: 41 LESVPPGFPAN--VTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLS 98
Query: 257 ALETFVMDGNELQVLPDSLFSGLRNLTTVSLR---NNKISVISMNTFQGATSIRTLDLSY 87
L++ + N ++ D +S L NL+ + L +N+++ I + F+ ++R+L L++
Sbjct: 99 HLKSLDLSHN---LISDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNH 155
Query: 86 NRLAFAPDSLYSPLNQLHKLQ 24
NRL + ++PL L LQ
Sbjct: 156 NRLHTLAEGTFTPLTALSHLQ 176
>AL159161-1|CAI17102.1| 754|Homo sapiens relaxin/insulin-like
family peptide receptor 2 protein.
Length = 754
Score = 72.9 bits (171), Expect = 8e-13
Identities = 45/156 (28%), Positives = 73/156 (46%), Gaps = 1/156 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FI 411
N + +F GL+ + + + NN L + + + +P L + L+ + I+ L F+
Sbjct: 219 NPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFL 278
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
S L L L RNQ+ +P L L LS N + EL+P LF DL+ L+ +
Sbjct: 279 SCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSS 338
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQ 123
N L L + F L+ L ++ L +I I+ FQ
Sbjct: 339 NPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQ 374
Score = 70.5 bits (165), Expect = 4e-12
Identities = 46/174 (26%), Positives = 80/174 (45%), Gaps = 1/174 (0%)
Frame = -3
Query: 545 DHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQ 369
+++ + + N +L + VF L+ + L + IR + + F L+ L L N
Sbjct: 137 NNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNC 196
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
+ L + + QLT L L N + ++ LF L +L M N L+ LP + + +
Sbjct: 197 ITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQM 256
Query: 188 RNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
L V L N+I ++ +TF S+ L L N++ F P+ +S L L +L
Sbjct: 257 PQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGEL 310
>AL138708-1|CAH73785.1| 754|Homo sapiens relaxin/insulin-like
family peptide receptor 2 protein.
Length = 754
Score = 72.9 bits (171), Expect = 8e-13
Identities = 45/156 (28%), Positives = 73/156 (46%), Gaps = 1/156 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FI 411
N + +F GL+ + + + NN L + + + +P L + L+ + I+ L F+
Sbjct: 219 NPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFL 278
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
S L L L RNQ+ +P L L LS N + EL+P LF DL+ L+ +
Sbjct: 279 SCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSS 338
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQ 123
N L L + F L+ L ++ L +I I+ FQ
Sbjct: 339 NPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQ 374
Score = 70.5 bits (165), Expect = 4e-12
Identities = 46/174 (26%), Positives = 80/174 (45%), Gaps = 1/174 (0%)
Frame = -3
Query: 545 DHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQ 369
+++ + + N +L + VF L+ + L + IR + + F L+ L L N
Sbjct: 137 NNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNC 196
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
+ L + + QLT L L N + ++ LF L +L M N L+ LP + + +
Sbjct: 197 ITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQM 256
Query: 188 RNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
L V L N+I ++ +TF S+ L L N++ F P+ +S L L +L
Sbjct: 257 PQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGEL 310
>AF453828-1|AAL73946.1| 754|Homo sapiens G protein-coupled receptor
affecting testicular descent protein.
Length = 754
Score = 72.9 bits (171), Expect = 8e-13
Identities = 45/156 (28%), Positives = 73/156 (46%), Gaps = 1/156 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FI 411
N + +F GL+ + + + NN L + + + +P L + L+ + I+ L F+
Sbjct: 219 NPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFL 278
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
S L L L RNQ+ +P L L LS N + EL+P LF DL+ L+ +
Sbjct: 279 SCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSS 338
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQ 123
N L L + F L+ L ++ L +I I+ FQ
Sbjct: 339 NPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQ 374
Score = 70.5 bits (165), Expect = 4e-12
Identities = 46/174 (26%), Positives = 80/174 (45%), Gaps = 1/174 (0%)
Frame = -3
Query: 545 DHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQ 369
+++ + + N +L + VF L+ + L + IR + + F L+ L L N
Sbjct: 137 NNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNC 196
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
+ L + + QLT L L N + ++ LF L +L M N L+ LP + + +
Sbjct: 197 ITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQM 256
Query: 188 RNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
L V L N+I ++ +TF S+ L L N++ F P+ +S L L +L
Sbjct: 257 PQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGEL 310
>AF403384-1|AAL69324.2| 754|Homo sapiens LGR8 protein.
Length = 754
Score = 72.9 bits (171), Expect = 8e-13
Identities = 45/156 (28%), Positives = 73/156 (46%), Gaps = 1/156 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FI 411
N + +F GL+ + + + NN L + + + +P L + L+ + I+ L F+
Sbjct: 219 NPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFL 278
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
S L L L RNQ+ +P L L LS N + EL+P LF DL+ L+ +
Sbjct: 279 SCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSS 338
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQ 123
N L L + F L+ L ++ L +I I+ FQ
Sbjct: 339 NPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQ 374
Score = 70.5 bits (165), Expect = 4e-12
Identities = 46/174 (26%), Positives = 80/174 (45%), Gaps = 1/174 (0%)
Frame = -3
Query: 545 DHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQ 369
+++ + + N +L + VF L+ + L + IR + + F L+ L L N
Sbjct: 137 NNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNC 196
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
+ L + + QLT L L N + ++ LF L +L M N L+ LP + + +
Sbjct: 197 ITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQM 256
Query: 188 RNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
L V L N+I ++ +TF S+ L L N++ F P+ +S L L +L
Sbjct: 257 PQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGEL 310
>BC046356-1|AAH46356.1| 421|Homo sapiens osteomodulin protein.
Length = 421
Score = 72.1 bits (169), Expect = 1e-12
Identities = 55/183 (30%), Positives = 87/183 (47%), Gaps = 4/183 (2%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLK--EAVFSNLPALRTLQLDLSSIRELPEEF 414
N + + F H++EI +S+N + K VF+ LP L L L+ +++ E P F
Sbjct: 101 NEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFP--F 158
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAE--LAPELFADLRALETFV 240
L L L N++ L + + G LT L L YN + + L ++FA + L
Sbjct: 159 PLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLN 218
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
+ N L+ +P L S L L SL NN IS I F + TL +S+N+L P +
Sbjct: 219 LCSNRLESMPPGLPSSLMYL---SLENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIPYN 275
Query: 59 LYS 51
+++
Sbjct: 276 IFN 278
>AY358872-1|AAQ89231.1| 421|Homo sapiens OMD protein.
Length = 421
Score = 72.1 bits (169), Expect = 1e-12
Identities = 55/183 (30%), Positives = 87/183 (47%), Gaps = 4/183 (2%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLK--EAVFSNLPALRTLQLDLSSIRELPEEF 414
N + + F H++EI +S+N + K VF+ LP L L L+ +++ E P F
Sbjct: 101 NEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFP--F 158
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAE--LAPELFADLRALETFV 240
L L L N++ L + + G LT L L YN + + L ++FA + L
Sbjct: 159 PLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLN 218
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
+ N L+ +P L S L L SL NN IS I F + TL +S+N+L P +
Sbjct: 219 LCSNRLESMPPGLPSSLMYL---SLENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIPYN 275
Query: 59 LYS 51
+++
Sbjct: 276 IFN 278
>AL137848-4|CAI16696.1| 421|Homo sapiens osteomodulin protein.
Length = 421
Score = 72.1 bits (169), Expect = 1e-12
Identities = 55/183 (30%), Positives = 87/183 (47%), Gaps = 4/183 (2%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLK--EAVFSNLPALRTLQLDLSSIRELPEEF 414
N + + F H++EI +S+N + K VF+ LP L L L+ +++ E P F
Sbjct: 101 NEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFP--F 158
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAE--LAPELFADLRALETFV 240
L L L N++ L + + G LT L L YN + + L ++FA + L
Sbjct: 159 PLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLN 218
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
+ N L+ +P L S L L SL NN IS I F + TL +S+N+L P +
Sbjct: 219 LCSNRLESMPPGLPSSLMYL---SLENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIPYN 275
Query: 59 LYS 51
+++
Sbjct: 276 IFN 278
>AB009589-1|BAA23982.1| 421|Homo sapiens Osteomodulin protein.
Length = 421
Score = 72.1 bits (169), Expect = 1e-12
Identities = 55/183 (30%), Positives = 87/183 (47%), Gaps = 4/183 (2%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLK--EAVFSNLPALRTLQLDLSSIRELPEEF 414
N + + F H++EI +S+N + K VF+ LP L L L+ +++ E P F
Sbjct: 101 NEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFP--F 158
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAE--LAPELFADLRALETFV 240
L L L N++ L + + G LT L L YN + + L ++FA + L
Sbjct: 159 PLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLN 218
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
+ N L+ +P L S L L SL NN IS I F + TL +S+N+L P +
Sbjct: 219 LCSNRLESMPPGLPSSLMYL---SLENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIPYN 275
Query: 59 LYS 51
+++
Sbjct: 276 IFN 278
>AB000114-1|BAA19055.1| 421|Homo sapiens osteomodulin protein.
Length = 421
Score = 72.1 bits (169), Expect = 1e-12
Identities = 55/183 (30%), Positives = 87/183 (47%), Gaps = 4/183 (2%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLK--EAVFSNLPALRTLQLDLSSIRELPEEF 414
N + + F H++EI +S+N + K VF+ LP L L L+ +++ E P F
Sbjct: 101 NEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFP--F 158
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAE--LAPELFADLRALETFV 240
L L L N++ L + + G LT L L YN + + L ++FA + L
Sbjct: 159 PLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLN 218
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
+ N L+ +P L S L L SL NN IS I F + TL +S+N+L P +
Sbjct: 219 LCSNRLESMPPGLPSSLMYL---SLENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIPYN 275
Query: 59 LYS 51
+++
Sbjct: 276 IFN 278
>DQ084202-1|AAY86709.1| 640|Homo sapiens netrin-G1 ligand splice
variant 4 protein.
Length = 640
Score = 71.7 bits (168), Expect = 2e-12
Identities = 52/200 (26%), Positives = 89/200 (44%), Gaps = 2/200 (1%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ RN R ++ F G + +++ +N T+ F L L+ L L + I +P
Sbjct: 107 LSRNHIRTIEIGAFNGPANPNTLELFDNRLATIPNGAFVYLSKLKELWLRNNPIESIPSY 166
Query: 416 FISNSP-LRTLSLAR-NQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETF 243
+ P LR L L +L + G + L L L+ + E+ P L L L+
Sbjct: 167 AFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREI-PNL-TPLIKLDEL 224
Query: 242 VMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPD 63
+ GN L + F GL +L + + ++I VI N F S+ ++L++N L P
Sbjct: 225 DLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIRVIERNAFDNLQSLVEINLAHNNLTLLPH 284
Query: 62 SLYSPLNQLHKLQTLTLAWN 3
L++PL+ L ++ WN
Sbjct: 285 DLFTPLHHLERIHLHHNPWN 304
Score = 49.2 bits (112), Expect = 1e-05
Identities = 38/139 (27%), Positives = 62/139 (44%), Gaps = 1/139 (0%)
Frame = -3
Query: 440 SIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADL 261
++R +P+ +N+ R L+L NQ++ + + + L L LS N + + F
Sbjct: 66 NLRGVPDGISTNT--RLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGP 123
Query: 260 RALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDL-SYN 84
T + N L +P+ F L L + LRNN I I F S+R LDL
Sbjct: 124 ANPNTLELFDNRLATIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELK 183
Query: 83 RLAFAPDSLYSPLNQLHKL 27
RL++ + + L+ L L
Sbjct: 184 RLSYISEGAFEGLSNLRYL 202
>BC073974-1|AAH73974.1| 359|Homo sapiens chondroadherin protein.
Length = 359
Score = 71.7 bits (168), Expect = 2e-12
Identities = 48/146 (32%), Positives = 70/146 (47%), Gaps = 1/146 (0%)
Frame = -3
Query: 557 FRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSL 381
FRGL + + +S+N L+ F +L L L LD + + ELP +S L L L
Sbjct: 95 FRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQL 154
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSL 201
N++R L +G L L LS NA++ L P D+ L F +D N+L P +
Sbjct: 155 NNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAA 214
Query: 200 FSGLRNLTTVSLRNNKISVISMNTFQ 123
S LR + + L +N + I N FQ
Sbjct: 215 LSKLRVVEELKLSHNPLKSIPDNAFQ 240
Score = 66.5 bits (155), Expect = 7e-11
Identities = 42/108 (38%), Positives = 54/108 (50%)
Frame = -3
Query: 398 LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 219
L +L L Q+R + RG QL L LS+N + L F DL L +D N++
Sbjct: 77 LVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVT 136
Query: 218 VLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLA 75
LP L S L NL + L NNKI + FQGA +R L LS N L+
Sbjct: 137 ELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALS 184
Score = 56.4 bits (130), Expect = 7e-08
Identities = 49/196 (25%), Positives = 78/196 (39%), Gaps = 1/196 (0%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE- 420
+ RN+F L + FR + ++ + + + + F L L L L + IR L
Sbjct: 58 LQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAG 117
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
F + L L L N++ LPR +L L L L+ N + EL F + L
Sbjct: 118 AFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLY 177
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
+ N L L + NL + N++S + L LS+N L PD+
Sbjct: 178 LSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDN 237
Query: 59 LYSPLNQLHKLQTLTL 12
+ + L+TL L
Sbjct: 238 AFQSFGRY--LETLWL 251
Score = 54.0 bits (124), Expect = 4e-07
Identities = 42/151 (27%), Positives = 66/151 (43%), Gaps = 2/151 (1%)
Frame = -3
Query: 530 IKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRALP 354
++++NN L+ F LR L L +++ L P L + RNQL + P
Sbjct: 152 LQLNNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYP 211
Query: 353 RSVLRGQTQLTSLTLSYNAVAELAPELFADL-RALETFVMDGNELQVLPDSLFSGLRNLT 177
+ L + L LS+N + + F R LET +D L+ D F G+ L
Sbjct: 212 SAALSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLK 271
Query: 176 TVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
V L NN+++ + N S+ TL L+ N
Sbjct: 272 HVHLENNRLNQLPSNF--PFDSLETLALTNN 300
>BC036360-1|AAH36360.1| 359|Homo sapiens chondroadherin protein.
Length = 359
Score = 71.7 bits (168), Expect = 2e-12
Identities = 48/146 (32%), Positives = 70/146 (47%), Gaps = 1/146 (0%)
Frame = -3
Query: 557 FRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSL 381
FRGL + + +S+N L+ F +L L L LD + + ELP +S L L L
Sbjct: 95 FRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQL 154
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSL 201
N++R L +G L L LS NA++ L P D+ L F +D N+L P +
Sbjct: 155 NNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAA 214
Query: 200 FSGLRNLTTVSLRNNKISVISMNTFQ 123
S LR + + L +N + I N FQ
Sbjct: 215 LSKLRVVEELKLSHNPLKSIPDNAFQ 240
Score = 66.5 bits (155), Expect = 7e-11
Identities = 42/108 (38%), Positives = 54/108 (50%)
Frame = -3
Query: 398 LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 219
L +L L Q+R + RG QL L LS+N + L F DL L +D N++
Sbjct: 77 LVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVT 136
Query: 218 VLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLA 75
LP L S L NL + L NNKI + FQGA +R L LS N L+
Sbjct: 137 ELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALS 184
Score = 56.4 bits (130), Expect = 7e-08
Identities = 49/196 (25%), Positives = 78/196 (39%), Gaps = 1/196 (0%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE- 420
+ RN+F L + FR + ++ + + + + F L L L L + IR L
Sbjct: 58 LQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAG 117
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
F + L L L N++ LPR +L L L L+ N + EL F + L
Sbjct: 118 AFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLY 177
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
+ N L L + NL + N++S + L LS+N L PD+
Sbjct: 178 LSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDN 237
Query: 59 LYSPLNQLHKLQTLTL 12
+ + L+TL L
Sbjct: 238 AFQSFGRY--LETLWL 251
Score = 54.0 bits (124), Expect = 4e-07
Identities = 42/151 (27%), Positives = 66/151 (43%), Gaps = 2/151 (1%)
Frame = -3
Query: 530 IKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRALP 354
++++NN L+ F LR L L +++ L P L + RNQL + P
Sbjct: 152 LQLNNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYP 211
Query: 353 RSVLRGQTQLTSLTLSYNAVAELAPELFADL-RALETFVMDGNELQVLPDSLFSGLRNLT 177
+ L + L LS+N + + F R LET +D L+ D F G+ L
Sbjct: 212 SAALSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLK 271
Query: 176 TVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
V L NN+++ + N S+ TL L+ N
Sbjct: 272 HVHLENNRLNQLPSNF--PFDSLETLALTNN 300
>AF371328-1|AAK51556.1| 359|Homo sapiens chondroadherin protein.
Length = 359
Score = 71.7 bits (168), Expect = 2e-12
Identities = 48/146 (32%), Positives = 70/146 (47%), Gaps = 1/146 (0%)
Frame = -3
Query: 557 FRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSL 381
FRGL + + +S+N L+ F +L L L LD + + ELP +S L L L
Sbjct: 95 FRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQL 154
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSL 201
N++R L +G L L LS NA++ L P D+ L F +D N+L P +
Sbjct: 155 NNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAA 214
Query: 200 FSGLRNLTTVSLRNNKISVISMNTFQ 123
S LR + + L +N + I N FQ
Sbjct: 215 LSKLRVVEELKLSHNPLKSIPDNAFQ 240
Score = 66.5 bits (155), Expect = 7e-11
Identities = 42/108 (38%), Positives = 54/108 (50%)
Frame = -3
Query: 398 LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 219
L +L L Q+R + RG QL L LS+N + L F DL L +D N++
Sbjct: 77 LVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVT 136
Query: 218 VLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLA 75
LP L S L NL + L NNKI + FQGA +R L LS N L+
Sbjct: 137 ELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALS 184
Score = 56.4 bits (130), Expect = 7e-08
Identities = 49/196 (25%), Positives = 78/196 (39%), Gaps = 1/196 (0%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE- 420
+ RN+F L + FR + ++ + + + + F L L L L + IR L
Sbjct: 58 LQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAG 117
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
F + L L L N++ LPR +L L L L+ N + EL F + L
Sbjct: 118 AFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLY 177
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
+ N L L + NL + N++S + L LS+N L PD+
Sbjct: 178 LSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDN 237
Query: 59 LYSPLNQLHKLQTLTL 12
+ + L+TL L
Sbjct: 238 AFQSFGRY--LETLWL 251
Score = 54.0 bits (124), Expect = 4e-07
Identities = 42/151 (27%), Positives = 66/151 (43%), Gaps = 2/151 (1%)
Frame = -3
Query: 530 IKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRALP 354
++++NN L+ F LR L L +++ L P L + RNQL + P
Sbjct: 152 LQLNNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYP 211
Query: 353 RSVLRGQTQLTSLTLSYNAVAELAPELFADL-RALETFVMDGNELQVLPDSLFSGLRNLT 177
+ L + L LS+N + + F R LET +D L+ D F G+ L
Sbjct: 212 SAALSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLK 271
Query: 176 TVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
V L NN+++ + N S+ TL L+ N
Sbjct: 272 HVHLENNRLNQLPSNF--PFDSLETLALTNN 300
>AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein
LRIG1 protein.
Length = 1093
Score = 71.3 bits (167), Expect = 2e-12
Identities = 53/199 (26%), Positives = 93/199 (46%), Gaps = 1/199 (0%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE- 420
+ +N L F+ L + ++ ++ N ++ F L +L L+L ++I +L +
Sbjct: 195 LSKNRITQLPVRAFK-LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDG 253
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
F S + L L N L + L G T L L LS N++A + + ++ + L V
Sbjct: 254 AFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELV 313
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
+ N L L + + L +L+ + L +N IS I+ F+G S+R LDL +N ++ +
Sbjct: 314 LSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIED 373
Query: 59 LYSPLNQLHKLQTLTLAWN 3
+ L L LTL N
Sbjct: 374 TSGAFSGLDSLSKLTLFGN 392
Score = 67.3 bits (157), Expect = 4e-11
Identities = 52/194 (26%), Positives = 87/194 (44%), Gaps = 4/194 (2%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ RN+ L F GL + + + N + + L AL L L +SI + +
Sbjct: 242 LQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRK 301
Query: 416 FISN-SPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
S L L L+ N L L L + L+ L LS+N+++ +A F LR+L
Sbjct: 302 GWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLD 361
Query: 239 MDGNELQ-VLPDS--LFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFA 69
+D NE+ + D+ FSGL +L+ ++L NKI ++ F G + L+L N +
Sbjct: 362 LDHNEISGTIEDTSGAFSGLDSLSKLTLFGNKIKSVAKRAFSGLEGLEHLNLGGNAIRSV 421
Query: 68 PDSLYSPLNQLHKL 27
+ + L +L
Sbjct: 422 QFDAFVKMKNLKEL 435
Score = 63.3 bits (147), Expect = 6e-10
Identities = 45/172 (26%), Positives = 83/172 (48%), Gaps = 1/172 (0%)
Frame = -3
Query: 536 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRAL 357
+ + +S N + A F +LP L+ + L+ + + +P ++S + +L L N++R++
Sbjct: 71 RSLNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGAASSHVVSLFLQHNKIRSV 130
Query: 356 PRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL-RNL 180
S L+ L L LS N + E+ F ++ + GN + L F GL R+L
Sbjct: 131 EGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSL 190
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
T+ L N+I+ + + F+ + LDL+ NR+ + LN L L+
Sbjct: 191 LTLRLSKNRITQLPVRAFK-LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLK 241
Score = 58.4 bits (135), Expect = 2e-08
Identities = 50/189 (26%), Positives = 85/189 (44%), Gaps = 2/189 (1%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP-EEFI 411
N +D F L ++QE+ ++NN LT ++ + + +L L + IR + +
Sbjct: 78 NKLSEIDPAGFEDLPNLQEVYLNNN-ELTAVPSLGAASSHVVSLFLQHNKIRSVEGSQLK 136
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADL-RALETFVMD 234
+ L L L+ N + + + + L L+ N + L F L R+L T +
Sbjct: 137 AYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLS 196
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
N + LP F L LT + L N+I +I TFQG S+ L L N ++ D +
Sbjct: 197 KNRITQLPVRAFK-LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAF 255
Query: 53 SPLNQLHKL 27
L+++H L
Sbjct: 256 WGLSKMHVL 264
Score = 58.4 bits (135), Expect = 2e-08
Identities = 46/173 (26%), Positives = 75/173 (43%), Gaps = 1/173 (0%)
Frame = -3
Query: 539 IQEIKISNNVPLTLKEAVFSNLP-ALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLR 363
I+E+ ++ N TL+ F L +L TL+L + I +LP L L L RN++R
Sbjct: 165 IKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAFKLPRLTQLDLNRNRIR 224
Query: 362 ALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRN 183
+ +G L L L N +++L F L + ++ N L + GL
Sbjct: 225 LIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTA 284
Query: 182 LTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
L + L NN I+ I + + L LS+N L + + L+ L L+
Sbjct: 285 LHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLR 337
Score = 58.4 bits (135), Expect = 2e-08
Identities = 42/170 (24%), Positives = 77/170 (45%), Gaps = 4/170 (2%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
NS ++S GL + ++ +SNN + +S L L L +++ L EE ++
Sbjct: 269 NSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLA 328
Query: 407 N-SPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVA---ELAPELFADLRALETFV 240
S L L L+ N + + +G L L L +N ++ E F+ L +L
Sbjct: 329 ELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLT 388
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLS 90
+ GN+++ + FSGL L ++L N I + + F +++ L +S
Sbjct: 389 LFGNKIKSVAKRAFSGLEGLEHLNLGGNAIRSVQFDAFVKMKNLKELHIS 438
>AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein
LIG-1 protein.
Length = 1094
Score = 71.3 bits (167), Expect = 2e-12
Identities = 53/199 (26%), Positives = 93/199 (46%), Gaps = 1/199 (0%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE- 420
+ +N L F+ L + ++ ++ N ++ F L +L L+L ++I +L +
Sbjct: 195 LSKNRITQLPVRAFK-LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDG 253
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
F S + L L N L + L G T L L LS N++A + + ++ + L V
Sbjct: 254 AFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELV 313
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
+ N L L + + L +L+ + L +N IS I+ F+G S+R LDL +N ++ +
Sbjct: 314 LSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIED 373
Query: 59 LYSPLNQLHKLQTLTLAWN 3
+ L L LTL N
Sbjct: 374 TSGAFSGLDSLSKLTLFGN 392
Score = 67.3 bits (157), Expect = 4e-11
Identities = 52/194 (26%), Positives = 87/194 (44%), Gaps = 4/194 (2%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ RN+ L F GL + + + N + + L AL L L +SI + +
Sbjct: 242 LQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRK 301
Query: 416 FISN-SPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
S L L L+ N L L L + L+ L LS+N+++ +A F LR+L
Sbjct: 302 GWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLD 361
Query: 239 MDGNELQ-VLPDS--LFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFA 69
+D NE+ + D+ FSGL +L+ ++L NKI ++ F G + L+L N +
Sbjct: 362 LDHNEISGTIEDTSGAFSGLDSLSKLTLFGNKIKSVAKRAFSGLEGLEHLNLGGNAIRSV 421
Query: 68 PDSLYSPLNQLHKL 27
+ + L +L
Sbjct: 422 QFDAFVKMKNLKEL 435
Score = 63.3 bits (147), Expect = 6e-10
Identities = 45/172 (26%), Positives = 83/172 (48%), Gaps = 1/172 (0%)
Frame = -3
Query: 536 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRAL 357
+ + +S N + A F +LP L+ + L+ + + +P ++S + +L L N++R++
Sbjct: 71 RSLNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGAASSHVVSLFLQHNKIRSV 130
Query: 356 PRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL-RNL 180
S L+ L L LS N + E+ F ++ + GN + L F GL R+L
Sbjct: 131 EGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSL 190
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
T+ L N+I+ + + F+ + LDL+ NR+ + LN L L+
Sbjct: 191 LTLRLSKNRITQLPVRAFK-LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLK 241
Score = 58.4 bits (135), Expect = 2e-08
Identities = 50/189 (26%), Positives = 85/189 (44%), Gaps = 2/189 (1%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP-EEFI 411
N +D F L ++QE+ ++NN LT ++ + + +L L + IR + +
Sbjct: 78 NKLSEIDPAGFEDLPNLQEVYLNNN-ELTAVPSLGAASSHVVSLFLQHNKIRSVEGSQLK 136
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADL-RALETFVMD 234
+ L L L+ N + + + + L L+ N + L F L R+L T +
Sbjct: 137 AYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLS 196
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
N + LP F L LT + L N+I +I TFQG S+ L L N ++ D +
Sbjct: 197 KNRITQLPVRAFK-LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAF 255
Query: 53 SPLNQLHKL 27
L+++H L
Sbjct: 256 WGLSKMHVL 264
Score = 58.4 bits (135), Expect = 2e-08
Identities = 46/173 (26%), Positives = 75/173 (43%), Gaps = 1/173 (0%)
Frame = -3
Query: 539 IQEIKISNNVPLTLKEAVFSNLP-ALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLR 363
I+E+ ++ N TL+ F L +L TL+L + I +LP L L L RN++R
Sbjct: 165 IKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAFKLPRLTQLDLNRNRIR 224
Query: 362 ALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRN 183
+ +G L L L N +++L F L + ++ N L + GL
Sbjct: 225 LIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTA 284
Query: 182 LTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
L + L NN I+ I + + L LS+N L + + L+ L L+
Sbjct: 285 LHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLR 337
Score = 58.4 bits (135), Expect = 2e-08
Identities = 42/170 (24%), Positives = 77/170 (45%), Gaps = 4/170 (2%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
NS ++S GL + ++ +SNN + +S L L L +++ L EE ++
Sbjct: 269 NSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLA 328
Query: 407 N-SPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVA---ELAPELFADLRALETFV 240
S L L L+ N + + +G L L L +N ++ E F+ L +L
Sbjct: 329 ELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLT 388
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLS 90
+ GN+++ + FSGL L ++L N I + + F +++ L +S
Sbjct: 389 LFGNKIKSVAKRAFSGLEGLEHLNLGGNAIRSVQFDAFVKMKNLKELHIS 438
>AY029183-1|AAK31796.1| 798|Homo sapiens SLIT1 isoform B protein.
Length = 798
Score = 70.9 bits (166), Expect = 3e-12
Identities = 44/154 (28%), Positives = 73/154 (47%), Gaps = 1/154 (0%)
Frame = -3
Query: 536 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRA 360
+ ++++ N + + F+ L LR LQL + I + F L L L RNQL
Sbjct: 47 ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHM 106
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
LP + + L+ L LS NA+ + + F L+ +D N++ + + F LR L
Sbjct: 107 LPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGL 166
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
++L NN I+ I +++F +RT L N L
Sbjct: 167 EVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 200
Score = 64.5 bits (150), Expect = 3e-10
Identities = 52/164 (31%), Positives = 79/164 (48%), Gaps = 1/164 (0%)
Frame = -3
Query: 491 AVFSNLPALRT-LQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSL 315
A+ +NLP T ++L+L+ I+ +P S P R L R P
Sbjct: 285 AIPANLPETMTEIRLELNGIKSIPPGAFS--PYRKLRRIRPLSFCSP-----------CR 331
Query: 314 TLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISM 135
LS N +AE+AP+ F LR+L + V+ GN++ LP +F GL L + L NKI+ I
Sbjct: 332 DLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRP 391
Query: 134 NTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
+ FQ ++ L L N++ ++ L +QTL LA N
Sbjct: 392 DAFQDLQNLSLLSLYDNKIQSLAKGTFT---SLRAIQTLHLAQN 432
Score = 61.7 bits (143), Expect = 2e-09
Identities = 37/130 (28%), Positives = 62/130 (47%), Gaps = 1/130 (0%)
Frame = -3
Query: 389 LSLARNQLRALPRS-VLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVL 213
L L N++ L + + + T L + LS N V+E+ F ++ + N+L+ +
Sbjct: 538 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 597
Query: 212 PDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLH 33
+F GL L T+ LRNN+IS I ++F G ++R L L N++ + L L
Sbjct: 598 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 657
Query: 32 KLQTLTLAWN 3
L L +N
Sbjct: 658 TLNLLANPFN 667
Score = 61.3 bits (142), Expect = 3e-09
Identities = 36/139 (25%), Positives = 66/139 (47%)
Frame = -3
Query: 443 SSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFAD 264
+ ++ +P+ N+ L L N + + ++ G QL L L N + + F D
Sbjct: 33 TGLQAIPKNIPRNT--ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDD 90
Query: 263 LRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
++ LE ++ N+L +LP+ LF + L+ + L N I I F+GAT ++ L L N
Sbjct: 91 MKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKN 150
Query: 83 RLAFAPDSLYSPLNQLHKL 27
+++ + + L L L
Sbjct: 151 QISCIEEGAFRALRGLEVL 169
Score = 58.8 bits (136), Expect = 1e-08
Identities = 32/119 (26%), Positives = 60/119 (50%)
Frame = -3
Query: 440 SIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADL 261
SI E F + L+ ++L+ N++ + G ++ L L+ N + + +F L
Sbjct: 546 SILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGL 605
Query: 260 RALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
L T ++ N + + + F+GLRN+ +SL +N+I+ +S F S+ TL+L N
Sbjct: 606 DGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 664
Score = 33.1 bits (72), Expect = 0.77
Identities = 24/100 (24%), Positives = 43/100 (43%), Gaps = 1/100 (1%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PE 420
+ N ++ F G + E+ ++ N +++ +F L LRTL L + I + +
Sbjct: 565 LSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHND 624
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYN 300
F +R LSL NQ+ + L++L L N
Sbjct: 625 SFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 664
Score = 30.7 bits (66), Expect = 4.1
Identities = 13/47 (27%), Positives = 27/47 (57%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL 450
+N ++ FR L ++ + ++NN T+ + F+++P LRT +L
Sbjct: 149 KNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRL 195
>AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 1534
Score = 70.9 bits (166), Expect = 3e-12
Identities = 44/154 (28%), Positives = 73/154 (47%), Gaps = 1/154 (0%)
Frame = -3
Query: 536 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRA 360
+ ++++ N + + F+ L LR LQL + I + F L L L RNQL
Sbjct: 64 ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHM 123
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
LP + + L+ L LS NA+ + + F L+ +D N++ + + F LR L
Sbjct: 124 LPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGL 183
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
++L NN I+ I +++F +RT L N L
Sbjct: 184 EVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 70.1 bits (164), Expect = 6e-12
Identities = 41/129 (31%), Positives = 67/129 (51%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
+ L N ++++P +L + LS N +AE+AP+ F LR+L + V+ GN++ LP
Sbjct: 314 IRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLP 373
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHK 30
+F GL L + L NKI+ I + FQ ++ L L N++ ++ L
Sbjct: 374 RGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFT---SLRA 430
Query: 29 LQTLTLAWN 3
+QTL LA N
Sbjct: 431 IQTLHLAQN 439
Score = 61.7 bits (143), Expect = 2e-09
Identities = 37/130 (28%), Positives = 62/130 (47%), Gaps = 1/130 (0%)
Frame = -3
Query: 389 LSLARNQLRALPRS-VLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVL 213
L L N++ L + + + T L + LS N V+E+ F ++ + N+L+ +
Sbjct: 545 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 604
Query: 212 PDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLH 33
+F GL L T+ LRNN+IS I ++F G ++R L L N++ + L L
Sbjct: 605 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 664
Query: 32 KLQTLTLAWN 3
L L +N
Sbjct: 665 TLNLLANPFN 674
Score = 61.3 bits (142), Expect = 3e-09
Identities = 36/139 (25%), Positives = 66/139 (47%)
Frame = -3
Query: 443 SSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFAD 264
+ ++ +P+ N+ L L N + + ++ G QL L L N + + F D
Sbjct: 50 TGLQAIPKNIPRNT--ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDD 107
Query: 263 LRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
++ LE ++ N+L +LP+ LF + L+ + L N I I F+GAT ++ L L N
Sbjct: 108 MKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKN 167
Query: 83 RLAFAPDSLYSPLNQLHKL 27
+++ + + L L L
Sbjct: 168 QISCIEEGAFRALRGLEVL 186
Score = 58.8 bits (136), Expect = 1e-08
Identities = 32/119 (26%), Positives = 60/119 (50%)
Frame = -3
Query: 440 SIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADL 261
SI E F + L+ ++L+ N++ + G ++ L L+ N + + +F L
Sbjct: 553 SILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGL 612
Query: 260 RALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
L T ++ N + + + F+GLRN+ +SL +N+I+ +S F S+ TL+L N
Sbjct: 613 DGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 671
Score = 56.4 bits (130), Expect = 7e-08
Identities = 29/103 (28%), Positives = 57/103 (55%)
Frame = -3
Query: 458 LQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAP 279
L LD + +P + + L+ + L+ N++ +L S +QLT+L LSYNA+ + P
Sbjct: 766 LYLDGNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPP 825
Query: 278 ELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKI 150
F LR+L + GN++ L + +F+ + +L+ +++ N +
Sbjct: 826 LAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPL 868
Score = 48.8 bits (111), Expect = 1e-05
Identities = 32/118 (27%), Positives = 56/118 (47%)
Frame = -3
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSL 201
+ LRALP+ + + +T L L N L P + + L+ + N++ L +S
Sbjct: 748 SNKHLRALPKGIPKN---VTELYLDGNQFT-LVPGQLSTFKYLQLVDLSNNKISSLSNSS 803
Query: 200 FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
F+ + LTT+ L N + I FQG S+R L L N ++ + +++ + L L
Sbjct: 804 FTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHL 861
Score = 47.2 bits (107), Expect = 4e-05
Identities = 24/90 (26%), Positives = 45/90 (50%), Gaps = 1/90 (1%)
Frame = -3
Query: 326 LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKIS 147
+T + L N + + P F+ R L + N++ + F GLR+L ++ L NKI+
Sbjct: 311 MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKIT 370
Query: 146 VISMNTFQGATSIRTLDLSYNRL-AFAPDS 60
+ F G +++ L L+ N++ PD+
Sbjct: 371 DLPRGVFGGLYTLQLLLLNANKINCIRPDA 400
Score = 39.5 bits (88), Expect = 0.009
Identities = 31/121 (25%), Positives = 52/121 (42%), Gaps = 1/121 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFI 411
N + + F ++ I +SNN + F L +L +L L + I +LP F
Sbjct: 319 NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFG 378
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L+ L L N++ + + L+ L+L N + LA F LRA++T +
Sbjct: 379 GLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQ 438
Query: 230 N 228
N
Sbjct: 439 N 439
Score = 39.1 bits (87), Expect = 0.012
Identities = 24/82 (29%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
Frame = -3
Query: 542 HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQL 366
++Q + +SNN +L + F+N+ L TL L ++++ +P F LR LSL N +
Sbjct: 785 YLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDI 844
Query: 365 RALPRSVLRGQTQLTSLTLSYN 300
L + T L+ L + N
Sbjct: 845 STLQEGIFADVTSLSHLAIGAN 866
Score = 33.1 bits (72), Expect = 0.77
Identities = 24/100 (24%), Positives = 43/100 (43%), Gaps = 1/100 (1%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PE 420
+ N ++ F G + E+ ++ N +++ +F L LRTL L + I + +
Sbjct: 572 LSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHND 631
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYN 300
F +R LSL NQ+ + L++L L N
Sbjct: 632 SFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 671
Score = 31.1 bits (67), Expect = 3.1
Identities = 44/202 (21%), Positives = 83/202 (41%), Gaps = 14/202 (6%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI-----REL 426
+N ++ FR L ++ + ++NN T+ + F+++P LRT +L + +
Sbjct: 166 KNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAW 225
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFAD------ 264
+++ P L + +L R + + Q + + S A P
Sbjct: 226 LSQWLRQRPTIGLFTQCSGPASL-RGLNVAEVQKSEFSCSGQGEAGRVPTCTLSSGSCPA 284
Query: 263 LRALETFVMD--GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLS 90
+ ++D G L +P +L +T + L N I I F +R +DLS
Sbjct: 285 MCTCSNGIVDCRGKGLTAIPANL---PETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLS 341
Query: 89 YNRLA-FAPDSLYSPLNQLHKL 27
N++A APD+ + L L+ L
Sbjct: 342 NNQIAEIAPDA-FQGLRSLNSL 362
>AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 1461
Score = 70.9 bits (166), Expect = 3e-12
Identities = 44/154 (28%), Positives = 73/154 (47%), Gaps = 1/154 (0%)
Frame = -3
Query: 536 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRA 360
+ ++++ N + + F+ L LR LQL + I + F L L L RNQL
Sbjct: 64 ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHM 123
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
LP + + L+ L LS NA+ + + F L+ +D N++ + + F LR L
Sbjct: 124 LPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGL 183
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
++L NN I+ I +++F +RT L N L
Sbjct: 184 EVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 70.1 bits (164), Expect = 6e-12
Identities = 41/129 (31%), Positives = 67/129 (51%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
+ L N ++++P +L + LS N +AE+AP+ F LR+L + V+ GN++ LP
Sbjct: 314 IRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLP 373
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHK 30
+F GL L + L NKI+ I + FQ ++ L L N++ ++ L
Sbjct: 374 RGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFT---SLRA 430
Query: 29 LQTLTLAWN 3
+QTL LA N
Sbjct: 431 IQTLHLAQN 439
Score = 61.7 bits (143), Expect = 2e-09
Identities = 37/130 (28%), Positives = 62/130 (47%), Gaps = 1/130 (0%)
Frame = -3
Query: 389 LSLARNQLRALPRS-VLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVL 213
L L N++ L + + + T L + LS N V+E+ F ++ + N+L+ +
Sbjct: 545 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 604
Query: 212 PDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLH 33
+F GL L T+ LRNN+IS I ++F G ++R L L N++ + L L
Sbjct: 605 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 664
Query: 32 KLQTLTLAWN 3
L L +N
Sbjct: 665 TLNLLANPFN 674
Score = 61.3 bits (142), Expect = 3e-09
Identities = 36/139 (25%), Positives = 66/139 (47%)
Frame = -3
Query: 443 SSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFAD 264
+ ++ +P+ N+ L L N + + ++ G QL L L N + + F D
Sbjct: 50 TGLQAIPKNIPRNT--ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDD 107
Query: 263 LRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
++ LE ++ N+L +LP+ LF + L+ + L N I I F+GAT ++ L L N
Sbjct: 108 MKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKN 167
Query: 83 RLAFAPDSLYSPLNQLHKL 27
+++ + + L L L
Sbjct: 168 QISCIEEGAFRALRGLEVL 186
Score = 58.8 bits (136), Expect = 1e-08
Identities = 32/119 (26%), Positives = 60/119 (50%)
Frame = -3
Query: 440 SIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADL 261
SI E F + L+ ++L+ N++ + G ++ L L+ N + + +F L
Sbjct: 553 SILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGL 612
Query: 260 RALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
L T ++ N + + + F+GLRN+ +SL +N+I+ +S F S+ TL+L N
Sbjct: 613 DGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 671
Score = 56.4 bits (130), Expect = 7e-08
Identities = 29/103 (28%), Positives = 57/103 (55%)
Frame = -3
Query: 458 LQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAP 279
L LD + +P + + L+ + L+ N++ +L S +QLT+L LSYNA+ + P
Sbjct: 766 LYLDGNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPP 825
Query: 278 ELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKI 150
F LR+L + GN++ L + +F+ + +L+ +++ N +
Sbjct: 826 LAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPL 868
Score = 48.8 bits (111), Expect = 1e-05
Identities = 32/118 (27%), Positives = 56/118 (47%)
Frame = -3
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSL 201
+ LRALP+ + + +T L L N L P + + L+ + N++ L +S
Sbjct: 748 SNKHLRALPKGIPKN---VTELYLDGNQFT-LVPGQLSTFKYLQLVDLSNNKISSLSNSS 803
Query: 200 FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
F+ + LTT+ L N + I FQG S+R L L N ++ + +++ + L L
Sbjct: 804 FTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHL 861
Score = 47.2 bits (107), Expect = 4e-05
Identities = 24/90 (26%), Positives = 45/90 (50%), Gaps = 1/90 (1%)
Frame = -3
Query: 326 LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKIS 147
+T + L N + + P F+ R L + N++ + F GLR+L ++ L NKI+
Sbjct: 311 MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKIT 370
Query: 146 VISMNTFQGATSIRTLDLSYNRL-AFAPDS 60
+ F G +++ L L+ N++ PD+
Sbjct: 371 DLPRGVFGGLYTLQLLLLNANKINCIRPDA 400
Score = 39.5 bits (88), Expect = 0.009
Identities = 31/121 (25%), Positives = 52/121 (42%), Gaps = 1/121 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFI 411
N + + F ++ I +SNN + F L +L +L L + I +LP F
Sbjct: 319 NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFG 378
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L+ L L N++ + + L+ L+L N + LA F LRA++T +
Sbjct: 379 GLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQ 438
Query: 230 N 228
N
Sbjct: 439 N 439
Score = 39.1 bits (87), Expect = 0.012
Identities = 24/82 (29%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
Frame = -3
Query: 542 HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQL 366
++Q + +SNN +L + F+N+ L TL L ++++ +P F LR LSL N +
Sbjct: 785 YLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDI 844
Query: 365 RALPRSVLRGQTQLTSLTLSYN 300
L + T L+ L + N
Sbjct: 845 STLQEGIFADVTSLSHLAIGAN 866
Score = 33.1 bits (72), Expect = 0.77
Identities = 24/100 (24%), Positives = 43/100 (43%), Gaps = 1/100 (1%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PE 420
+ N ++ F G + E+ ++ N +++ +F L LRTL L + I + +
Sbjct: 572 LSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHND 631
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYN 300
F +R LSL NQ+ + L++L L N
Sbjct: 632 SFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 671
Score = 31.1 bits (67), Expect = 3.1
Identities = 44/202 (21%), Positives = 83/202 (41%), Gaps = 14/202 (6%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI-----REL 426
+N ++ FR L ++ + ++NN T+ + F+++P LRT +L + +
Sbjct: 166 KNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAW 225
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFAD------ 264
+++ P L + +L R + + Q + + S A P
Sbjct: 226 LSQWLRQRPTIGLFTQCSGPASL-RGLNVAEVQKSEFSCSGQGEAGRVPTCTLSSGSCPA 284
Query: 263 LRALETFVMD--GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLS 90
+ ++D G L +P +L +T + L N I I F +R +DLS
Sbjct: 285 MCTCSNGIVDCRGKGLTAIPANL---PETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLS 341
Query: 89 YNRLA-FAPDSLYSPLNQLHKL 27
N++A APD+ + L L+ L
Sbjct: 342 NNQIAEIAPDA-FQGLRSLNSL 362
>AL512424-3|CAI14257.1| 409|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 409
Score = 70.9 bits (166), Expect = 3e-12
Identities = 44/154 (28%), Positives = 73/154 (47%), Gaps = 1/154 (0%)
Frame = -3
Query: 536 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRA 360
+ ++++ N + + F+ L LR LQL + I + F L L L RNQL
Sbjct: 64 ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHM 123
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
LP + + L+ L LS NA+ + + F L+ +D N++ + + F LR L
Sbjct: 124 LPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGL 183
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
++L NN I+ I +++F +RT L N L
Sbjct: 184 EVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 61.3 bits (142), Expect = 3e-09
Identities = 36/139 (25%), Positives = 66/139 (47%)
Frame = -3
Query: 443 SSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFAD 264
+ ++ +P+ N+ L L N + + ++ G QL L L N + + F D
Sbjct: 50 TGLQAIPKNIPRNT--ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDD 107
Query: 263 LRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
++ LE ++ N+L +LP+ LF + L+ + L N I I F+GAT ++ L L N
Sbjct: 108 MKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKN 167
Query: 83 RLAFAPDSLYSPLNQLHKL 27
+++ + + L L L
Sbjct: 168 QISCIEEGAFRALRGLEVL 186
Score = 35.5 bits (78), Expect = 0.14
Identities = 16/44 (36%), Positives = 26/44 (59%)
Frame = -3
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTL 99
N ++ +P FS R L + L NN+I+ I+ + FQG S+ +L
Sbjct: 319 NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSL 362
Score = 33.5 bits (73), Expect = 0.58
Identities = 15/48 (31%), Positives = 27/48 (56%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALET 246
+ L N ++++P +L + LS N +AE+AP+ F LR+L +
Sbjct: 314 IRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNS 361
Score = 33.1 bits (72), Expect = 0.77
Identities = 45/204 (22%), Positives = 84/204 (41%), Gaps = 14/204 (6%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI-----REL 426
+N ++ FR L ++ + ++NN T+ + F+++P LRT +L + +
Sbjct: 166 KNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAW 225
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFAD------ 264
+++ P L + +L R + + Q + + S A P
Sbjct: 226 LSQWLRQRPTIGLFTQCSGPASL-RGLNVAEVQKSEFSCSGQGEAGRVPTCTLSSGSCPA 284
Query: 263 LRALETFVMD--GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLS 90
+ ++D G L +P +L +T + L N I I F +R +DLS
Sbjct: 285 MCTCSNGIVDCRGKGLTAIPANL---PETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLS 341
Query: 89 YNRLA-FAPDSLYSPLNQLHKLQT 21
N++A APD+ + L L+ L T
Sbjct: 342 NNQIAEIAPDA-FQGLRSLNSLHT 364
>AL512424-1|CAI14255.1| 782|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 782
Score = 70.9 bits (166), Expect = 3e-12
Identities = 44/154 (28%), Positives = 73/154 (47%), Gaps = 1/154 (0%)
Frame = -3
Query: 536 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRA 360
+ ++++ N + + F+ L LR LQL + I + F L L L RNQL
Sbjct: 47 ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHM 106
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
LP + + L+ L LS NA+ + + F L+ +D N++ + + F LR L
Sbjct: 107 LPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGL 166
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
++L NN I+ I +++F +RT L N L
Sbjct: 167 EVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 200
Score = 64.9 bits (151), Expect = 2e-10
Identities = 53/164 (32%), Positives = 80/164 (48%), Gaps = 1/164 (0%)
Frame = -3
Query: 491 AVFSNLPALRT-LQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSL 315
A+ +NLP T ++L+L+ I+ +P S P R L R P S
Sbjct: 285 AIPANLPETMTEIRLELNGIKSIPPGAFS--PYRKLR------RICPLSFCS-----PCR 331
Query: 314 TLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISM 135
LS N +AE+AP+ F LR+L + V+ GN++ LP +F GL L + L NKI+ I
Sbjct: 332 DLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRP 391
Query: 134 NTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
+ FQ ++ L L N++ ++ L +QTL LA N
Sbjct: 392 DAFQDLQNLSLLSLYDNKIQSLAKGTFT---SLRAIQTLHLAQN 432
Score = 61.7 bits (143), Expect = 2e-09
Identities = 37/130 (28%), Positives = 62/130 (47%), Gaps = 1/130 (0%)
Frame = -3
Query: 389 LSLARNQLRALPRS-VLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVL 213
L L N++ L + + + T L + LS N V+E+ F ++ + N+L+ +
Sbjct: 538 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 597
Query: 212 PDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLH 33
+F GL L T+ LRNN+IS I ++F G ++R L L N++ + L L
Sbjct: 598 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 657
Query: 32 KLQTLTLAWN 3
L L +N
Sbjct: 658 TLNLLANPFN 667
Score = 61.3 bits (142), Expect = 3e-09
Identities = 36/139 (25%), Positives = 66/139 (47%)
Frame = -3
Query: 443 SSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFAD 264
+ ++ +P+ N+ L L N + + ++ G QL L L N + + F D
Sbjct: 33 TGLQAIPKNIPRNT--ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDD 90
Query: 263 LRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
++ LE ++ N+L +LP+ LF + L+ + L N I I F+GAT ++ L L N
Sbjct: 91 MKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKN 150
Query: 83 RLAFAPDSLYSPLNQLHKL 27
+++ + + L L L
Sbjct: 151 QISCIEEGAFRALRGLEVL 169
Score = 58.8 bits (136), Expect = 1e-08
Identities = 32/119 (26%), Positives = 60/119 (50%)
Frame = -3
Query: 440 SIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADL 261
SI E F + L+ ++L+ N++ + G ++ L L+ N + + +F L
Sbjct: 546 SILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGL 605
Query: 260 RALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
L T ++ N + + + F+GLRN+ +SL +N+I+ +S F S+ TL+L N
Sbjct: 606 DGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 664
Score = 33.1 bits (72), Expect = 0.77
Identities = 24/100 (24%), Positives = 43/100 (43%), Gaps = 1/100 (1%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PE 420
+ N ++ F G + E+ ++ N +++ +F L LRTL L + I + +
Sbjct: 565 LSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHND 624
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYN 300
F +R LSL NQ+ + L++L L N
Sbjct: 625 SFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 664
Score = 30.7 bits (66), Expect = 4.1
Identities = 13/47 (27%), Positives = 27/47 (57%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL 450
+N ++ FR L ++ + ++NN T+ + F+++P LRT +L
Sbjct: 149 KNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRL 195
>AL442123-4|CAH70918.1| 1534|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 1534
Score = 70.9 bits (166), Expect = 3e-12
Identities = 44/154 (28%), Positives = 73/154 (47%), Gaps = 1/154 (0%)
Frame = -3
Query: 536 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRA 360
+ ++++ N + + F+ L LR LQL + I + F L L L RNQL
Sbjct: 64 ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHM 123
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
LP + + L+ L LS NA+ + + F L+ +D N++ + + F LR L
Sbjct: 124 LPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGL 183
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
++L NN I+ I +++F +RT L N L
Sbjct: 184 EVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 70.1 bits (164), Expect = 6e-12
Identities = 41/129 (31%), Positives = 67/129 (51%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
+ L N ++++P +L + LS N +AE+AP+ F LR+L + V+ GN++ LP
Sbjct: 314 IRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLP 373
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHK 30
+F GL L + L NKI+ I + FQ ++ L L N++ ++ L
Sbjct: 374 RGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFT---SLRA 430
Query: 29 LQTLTLAWN 3
+QTL LA N
Sbjct: 431 IQTLHLAQN 439
Score = 61.7 bits (143), Expect = 2e-09
Identities = 37/130 (28%), Positives = 62/130 (47%), Gaps = 1/130 (0%)
Frame = -3
Query: 389 LSLARNQLRALPRS-VLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVL 213
L L N++ L + + + T L + LS N V+E+ F ++ + N+L+ +
Sbjct: 545 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 604
Query: 212 PDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLH 33
+F GL L T+ LRNN+IS I ++F G ++R L L N++ + L L
Sbjct: 605 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 664
Query: 32 KLQTLTLAWN 3
L L +N
Sbjct: 665 TLNLLANPFN 674
Score = 61.3 bits (142), Expect = 3e-09
Identities = 36/139 (25%), Positives = 66/139 (47%)
Frame = -3
Query: 443 SSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFAD 264
+ ++ +P+ N+ L L N + + ++ G QL L L N + + F D
Sbjct: 50 TGLQAIPKNIPRNT--ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDD 107
Query: 263 LRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
++ LE ++ N+L +LP+ LF + L+ + L N I I F+GAT ++ L L N
Sbjct: 108 MKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKN 167
Query: 83 RLAFAPDSLYSPLNQLHKL 27
+++ + + L L L
Sbjct: 168 QISCIEEGAFRALRGLEVL 186
Score = 58.8 bits (136), Expect = 1e-08
Identities = 32/119 (26%), Positives = 60/119 (50%)
Frame = -3
Query: 440 SIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADL 261
SI E F + L+ ++L+ N++ + G ++ L L+ N + + +F L
Sbjct: 553 SILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGL 612
Query: 260 RALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
L T ++ N + + + F+GLRN+ +SL +N+I+ +S F S+ TL+L N
Sbjct: 613 DGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 671
Score = 56.4 bits (130), Expect = 7e-08
Identities = 29/103 (28%), Positives = 57/103 (55%)
Frame = -3
Query: 458 LQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAP 279
L LD + +P + + L+ + L+ N++ +L S +QLT+L LSYNA+ + P
Sbjct: 766 LYLDGNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPP 825
Query: 278 ELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKI 150
F LR+L + GN++ L + +F+ + +L+ +++ N +
Sbjct: 826 LAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPL 868
Score = 48.8 bits (111), Expect = 1e-05
Identities = 32/118 (27%), Positives = 56/118 (47%)
Frame = -3
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSL 201
+ LRALP+ + + +T L L N L P + + L+ + N++ L +S
Sbjct: 748 SNKHLRALPKGIPKN---VTELYLDGNQFT-LVPGQLSTFKYLQLVDLSNNKISSLSNSS 803
Query: 200 FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
F+ + LTT+ L N + I FQG S+R L L N ++ + +++ + L L
Sbjct: 804 FTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHL 861
Score = 47.2 bits (107), Expect = 4e-05
Identities = 24/90 (26%), Positives = 45/90 (50%), Gaps = 1/90 (1%)
Frame = -3
Query: 326 LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKIS 147
+T + L N + + P F+ R L + N++ + F GLR+L ++ L NKI+
Sbjct: 311 MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKIT 370
Query: 146 VISMNTFQGATSIRTLDLSYNRL-AFAPDS 60
+ F G +++ L L+ N++ PD+
Sbjct: 371 DLPRGVFGGLYTLQLLLLNANKINCIRPDA 400
Score = 39.5 bits (88), Expect = 0.009
Identities = 31/121 (25%), Positives = 52/121 (42%), Gaps = 1/121 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFI 411
N + + F ++ I +SNN + F L +L +L L + I +LP F
Sbjct: 319 NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFG 378
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L+ L L N++ + + L+ L+L N + LA F LRA++T +
Sbjct: 379 GLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQ 438
Query: 230 N 228
N
Sbjct: 439 N 439
Score = 39.1 bits (87), Expect = 0.012
Identities = 24/82 (29%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
Frame = -3
Query: 542 HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQL 366
++Q + +SNN +L + F+N+ L TL L ++++ +P F LR LSL N +
Sbjct: 785 YLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDI 844
Query: 365 RALPRSVLRGQTQLTSLTLSYN 300
L + T L+ L + N
Sbjct: 845 STLQEGIFADVTSLSHLAIGAN 866
Score = 33.1 bits (72), Expect = 0.77
Identities = 24/100 (24%), Positives = 43/100 (43%), Gaps = 1/100 (1%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PE 420
+ N ++ F G + E+ ++ N +++ +F L LRTL L + I + +
Sbjct: 572 LSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHND 631
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYN 300
F +R LSL NQ+ + L++L L N
Sbjct: 632 SFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 671
Score = 31.1 bits (67), Expect = 3.1
Identities = 44/202 (21%), Positives = 83/202 (41%), Gaps = 14/202 (6%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI-----REL 426
+N ++ FR L ++ + ++NN T+ + F+++P LRT +L + +
Sbjct: 166 KNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAW 225
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFAD------ 264
+++ P L + +L R + + Q + + S A P
Sbjct: 226 LSQWLRQRPTIGLFTQCSGPASL-RGLNVAEVQKSEFSCSGQGEAGRVPTCTLSSGSCPA 284
Query: 263 LRALETFVMD--GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLS 90
+ ++D G L +P +L +T + L N I I F +R +DLS
Sbjct: 285 MCTCSNGIVDCRGKGLTAIPANL---PETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLS 341
Query: 89 YNRLA-FAPDSLYSPLNQLHKL 27
N++A APD+ + L L+ L
Sbjct: 342 NNQIAEIAPDA-FQGLRSLNSL 362
>AL442123-3|CAH70917.1| 1461|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 1461
Score = 70.9 bits (166), Expect = 3e-12
Identities = 44/154 (28%), Positives = 73/154 (47%), Gaps = 1/154 (0%)
Frame = -3
Query: 536 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRA 360
+ ++++ N + + F+ L LR LQL + I + F L L L RNQL
Sbjct: 64 ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHM 123
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
LP + + L+ L LS NA+ + + F L+ +D N++ + + F LR L
Sbjct: 124 LPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGL 183
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
++L NN I+ I +++F +RT L N L
Sbjct: 184 EVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 70.1 bits (164), Expect = 6e-12
Identities = 41/129 (31%), Positives = 67/129 (51%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
+ L N ++++P +L + LS N +AE+AP+ F LR+L + V+ GN++ LP
Sbjct: 314 IRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLP 373
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHK 30
+F GL L + L NKI+ I + FQ ++ L L N++ ++ L
Sbjct: 374 RGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFT---SLRA 430
Query: 29 LQTLTLAWN 3
+QTL LA N
Sbjct: 431 IQTLHLAQN 439
Score = 61.7 bits (143), Expect = 2e-09
Identities = 37/130 (28%), Positives = 62/130 (47%), Gaps = 1/130 (0%)
Frame = -3
Query: 389 LSLARNQLRALPRS-VLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVL 213
L L N++ L + + + T L + LS N V+E+ F ++ + N+L+ +
Sbjct: 545 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 604
Query: 212 PDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLH 33
+F GL L T+ LRNN+IS I ++F G ++R L L N++ + L L
Sbjct: 605 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 664
Query: 32 KLQTLTLAWN 3
L L +N
Sbjct: 665 TLNLLANPFN 674
Score = 61.3 bits (142), Expect = 3e-09
Identities = 36/139 (25%), Positives = 66/139 (47%)
Frame = -3
Query: 443 SSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFAD 264
+ ++ +P+ N+ L L N + + ++ G QL L L N + + F D
Sbjct: 50 TGLQAIPKNIPRNT--ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDD 107
Query: 263 LRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
++ LE ++ N+L +LP+ LF + L+ + L N I I F+GAT ++ L L N
Sbjct: 108 MKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKN 167
Query: 83 RLAFAPDSLYSPLNQLHKL 27
+++ + + L L L
Sbjct: 168 QISCIEEGAFRALRGLEVL 186
Score = 58.8 bits (136), Expect = 1e-08
Identities = 32/119 (26%), Positives = 60/119 (50%)
Frame = -3
Query: 440 SIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADL 261
SI E F + L+ ++L+ N++ + G ++ L L+ N + + +F L
Sbjct: 553 SILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGL 612
Query: 260 RALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
L T ++ N + + + F+GLRN+ +SL +N+I+ +S F S+ TL+L N
Sbjct: 613 DGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 671
Score = 56.4 bits (130), Expect = 7e-08
Identities = 29/103 (28%), Positives = 57/103 (55%)
Frame = -3
Query: 458 LQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAP 279
L LD + +P + + L+ + L+ N++ +L S +QLT+L LSYNA+ + P
Sbjct: 766 LYLDGNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPP 825
Query: 278 ELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKI 150
F LR+L + GN++ L + +F+ + +L+ +++ N +
Sbjct: 826 LAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPL 868
Score = 48.8 bits (111), Expect = 1e-05
Identities = 32/118 (27%), Positives = 56/118 (47%)
Frame = -3
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSL 201
+ LRALP+ + + +T L L N L P + + L+ + N++ L +S
Sbjct: 748 SNKHLRALPKGIPKN---VTELYLDGNQFT-LVPGQLSTFKYLQLVDLSNNKISSLSNSS 803
Query: 200 FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
F+ + LTT+ L N + I FQG S+R L L N ++ + +++ + L L
Sbjct: 804 FTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHL 861
Score = 47.2 bits (107), Expect = 4e-05
Identities = 24/90 (26%), Positives = 45/90 (50%), Gaps = 1/90 (1%)
Frame = -3
Query: 326 LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKIS 147
+T + L N + + P F+ R L + N++ + F GLR+L ++ L NKI+
Sbjct: 311 MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKIT 370
Query: 146 VISMNTFQGATSIRTLDLSYNRL-AFAPDS 60
+ F G +++ L L+ N++ PD+
Sbjct: 371 DLPRGVFGGLYTLQLLLLNANKINCIRPDA 400
Score = 39.5 bits (88), Expect = 0.009
Identities = 31/121 (25%), Positives = 52/121 (42%), Gaps = 1/121 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFI 411
N + + F ++ I +SNN + F L +L +L L + I +LP F
Sbjct: 319 NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFG 378
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L+ L L N++ + + L+ L+L N + LA F LRA++T +
Sbjct: 379 GLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQ 438
Query: 230 N 228
N
Sbjct: 439 N 439
Score = 39.1 bits (87), Expect = 0.012
Identities = 24/82 (29%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
Frame = -3
Query: 542 HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQL 366
++Q + +SNN +L + F+N+ L TL L ++++ +P F LR LSL N +
Sbjct: 785 YLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDI 844
Query: 365 RALPRSVLRGQTQLTSLTLSYN 300
L + T L+ L + N
Sbjct: 845 STLQEGIFADVTSLSHLAIGAN 866
Score = 33.1 bits (72), Expect = 0.77
Identities = 24/100 (24%), Positives = 43/100 (43%), Gaps = 1/100 (1%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PE 420
+ N ++ F G + E+ ++ N +++ +F L LRTL L + I + +
Sbjct: 572 LSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHND 631
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYN 300
F +R LSL NQ+ + L++L L N
Sbjct: 632 SFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 671
Score = 31.1 bits (67), Expect = 3.1
Identities = 44/202 (21%), Positives = 83/202 (41%), Gaps = 14/202 (6%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI-----REL 426
+N ++ FR L ++ + ++NN T+ + F+++P LRT +L + +
Sbjct: 166 KNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAW 225
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFAD------ 264
+++ P L + +L R + + Q + + S A P
Sbjct: 226 LSQWLRQRPTIGLFTQCSGPASL-RGLNVAEVQKSEFSCSGQGEAGRVPTCTLSSGSCPA 284
Query: 263 LRALETFVMD--GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLS 90
+ ++D G L +P +L +T + L N I I F +R +DLS
Sbjct: 285 MCTCSNGIVDCRGKGLTAIPANL---PETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLS 341
Query: 89 YNRLA-FAPDSLYSPLNQLHKL 27
N++A APD+ + L L+ L
Sbjct: 342 NNQIAEIAPDA-FQGLRSLNSL 362
>BC146761-1|AAI46762.1| 1534|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 1534
Score = 70.5 bits (165), Expect = 4e-12
Identities = 44/154 (28%), Positives = 73/154 (47%), Gaps = 1/154 (0%)
Frame = -3
Query: 536 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRA 360
+ ++++ N + + F+ L LR LQL + I + F L L L RNQL
Sbjct: 64 ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGVVERGAFDDMKELERLRLNRNQLHM 123
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
LP + + L+ L LS NA+ + + F L+ +D N++ + + F LR L
Sbjct: 124 LPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGL 183
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
++L NN I+ I +++F +RT L N L
Sbjct: 184 EVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 70.1 bits (164), Expect = 6e-12
Identities = 41/129 (31%), Positives = 67/129 (51%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
+ L N ++++P +L + LS N +AE+AP+ F LR+L + V+ GN++ LP
Sbjct: 314 IRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLP 373
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHK 30
+F GL L + L NKI+ I + FQ ++ L L N++ ++ L
Sbjct: 374 RGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFT---SLRA 430
Query: 29 LQTLTLAWN 3
+QTL LA N
Sbjct: 431 IQTLHLAQN 439
Score = 61.7 bits (143), Expect = 2e-09
Identities = 37/130 (28%), Positives = 62/130 (47%), Gaps = 1/130 (0%)
Frame = -3
Query: 389 LSLARNQLRALPRS-VLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVL 213
L L N++ L + + + T L + LS N V+E+ F ++ + N+L+ +
Sbjct: 545 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 604
Query: 212 PDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLH 33
+F GL L T+ LRNN+IS I ++F G ++R L L N++ + L L
Sbjct: 605 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 664
Query: 32 KLQTLTLAWN 3
L L +N
Sbjct: 665 TLNLLANPFN 674
Score = 60.9 bits (141), Expect = 3e-09
Identities = 36/139 (25%), Positives = 66/139 (47%)
Frame = -3
Query: 443 SSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFAD 264
+ ++ +P+ N+ L L N + + ++ G QL L L N + + F D
Sbjct: 50 TGLQAIPKNIPRNT--ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGVVERGAFDD 107
Query: 263 LRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
++ LE ++ N+L +LP+ LF + L+ + L N I I F+GAT ++ L L N
Sbjct: 108 MKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKN 167
Query: 83 RLAFAPDSLYSPLNQLHKL 27
+++ + + L L L
Sbjct: 168 QISCIEEGAFRALRGLEVL 186
Score = 58.8 bits (136), Expect = 1e-08
Identities = 32/119 (26%), Positives = 60/119 (50%)
Frame = -3
Query: 440 SIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADL 261
SI E F + L+ ++L+ N++ + G ++ L L+ N + + +F L
Sbjct: 553 SILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGL 612
Query: 260 RALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
L T ++ N + + + F+GLRN+ +SL +N+I+ +S F S+ TL+L N
Sbjct: 613 DGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 671
Score = 56.4 bits (130), Expect = 7e-08
Identities = 29/103 (28%), Positives = 57/103 (55%)
Frame = -3
Query: 458 LQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAP 279
L LD + +P + + L+ + L+ N++ +L S +QLT+L LSYNA+ + P
Sbjct: 766 LYLDGNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPP 825
Query: 278 ELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKI 150
F LR+L + GN++ L + +F+ + +L+ +++ N +
Sbjct: 826 LAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPL 868
Score = 48.8 bits (111), Expect = 1e-05
Identities = 32/118 (27%), Positives = 56/118 (47%)
Frame = -3
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSL 201
+ LRALP+ + + +T L L N L P + + L+ + N++ L +S
Sbjct: 748 SNKHLRALPKGIPKN---VTELYLDGNQFT-LVPGQLSTFKYLQLVDLSNNKISSLSNSS 803
Query: 200 FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
F+ + LTT+ L N + I FQG S+R L L N ++ + +++ + L L
Sbjct: 804 FTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHL 861
Score = 47.2 bits (107), Expect = 4e-05
Identities = 24/90 (26%), Positives = 45/90 (50%), Gaps = 1/90 (1%)
Frame = -3
Query: 326 LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKIS 147
+T + L N + + P F+ R L + N++ + F GLR+L ++ L NKI+
Sbjct: 311 MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKIT 370
Query: 146 VISMNTFQGATSIRTLDLSYNRL-AFAPDS 60
+ F G +++ L L+ N++ PD+
Sbjct: 371 DLPRGVFGGLYTLQLLLLNANKINCIRPDA 400
Score = 39.5 bits (88), Expect = 0.009
Identities = 31/121 (25%), Positives = 52/121 (42%), Gaps = 1/121 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFI 411
N + + F ++ I +SNN + F L +L +L L + I +LP F
Sbjct: 319 NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFG 378
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L+ L L N++ + + L+ L+L N + LA F LRA++T +
Sbjct: 379 GLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQ 438
Query: 230 N 228
N
Sbjct: 439 N 439
Score = 39.1 bits (87), Expect = 0.012
Identities = 24/82 (29%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
Frame = -3
Query: 542 HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQL 366
++Q + +SNN +L + F+N+ L TL L ++++ +P F LR LSL N +
Sbjct: 785 YLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDI 844
Query: 365 RALPRSVLRGQTQLTSLTLSYN 300
L + T L+ L + N
Sbjct: 845 STLQEGIFADVTSLSHLAIGAN 866
Score = 33.1 bits (72), Expect = 0.77
Identities = 24/100 (24%), Positives = 43/100 (43%), Gaps = 1/100 (1%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PE 420
+ N ++ F G + E+ ++ N +++ +F L LRTL L + I + +
Sbjct: 572 LSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHND 631
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYN 300
F +R LSL NQ+ + L++L L N
Sbjct: 632 SFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 671
Score = 31.1 bits (67), Expect = 3.1
Identities = 44/202 (21%), Positives = 83/202 (41%), Gaps = 14/202 (6%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI-----REL 426
+N ++ FR L ++ + ++NN T+ + F+++P LRT +L + +
Sbjct: 166 KNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAW 225
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFAD------ 264
+++ P L + +L R + + Q + + S A P
Sbjct: 226 LSQWLRQRPTIGLFTQCSGPASL-RGLNVAEVQKSEFSCSGQGEAGRVPTCTLSSGSCPA 284
Query: 263 LRALETFVMD--GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLS 90
+ ++D G L +P +L +T + L N I I F +R +DLS
Sbjct: 285 MCTCSNGIVDCRGKGLTAIPANL---PETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLS 341
Query: 89 YNRLA-FAPDSLYSPLNQLHKL 27
N++A APD+ + L L+ L
Sbjct: 342 NNQIAEIAPDA-FQGLRSLNSL 362
>BC142616-1|AAI42617.1| 789|Homo sapiens leucine rich repeat and
fibronectin type III domain containing 2 protein.
Length = 789
Score = 70.5 bits (165), Expect = 4e-12
Identities = 50/164 (30%), Positives = 79/164 (48%), Gaps = 3/164 (1%)
Frame = -3
Query: 533 EIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRAL 357
E+++ N + + F+N+ L L L ++I + P F+ LR+L L N+L +L
Sbjct: 56 ELRLGGNFIIHISRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSL 115
Query: 356 PRSVLRGQTQLTSLTLSYNAVAELAPELFAD-LRALETFVMDGNELQVLPDSLFSGLRNL 180
LRG L L ++ N + +A E F D L LE + N L LP + NL
Sbjct: 116 GEDTLRGLVNLQHLIVNNNQLGGIADEAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNL 175
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL-AFAPDSLYS 51
+SL +N + I+ TF + LDL+ NRL PD +++
Sbjct: 176 HQLSLDHNLLDHIAEGTFADLQKLARLDLTSNRLQKLPPDPIFA 219
Score = 62.5 bits (145), Expect = 1e-09
Identities = 42/123 (34%), Positives = 62/123 (50%), Gaps = 2/123 (1%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
L L N + + R T L LTLS N ++ + P F DL +L + +D N L L
Sbjct: 57 LRLGGNFIIHISRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLG 116
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQG-ATSIRTLDLSYNRLAFAP-DSLYSPLNQL 36
+ GL NL + + NN++ I+ F+ ++ LDLSYN L P DS+ +N L
Sbjct: 117 EDTLRGLVNLQHLIVNNNQLGGIADEAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVN-L 175
Query: 35 HKL 27
H+L
Sbjct: 176 HQL 178
>BC003578-1|AAH03578.1| 628|Homo sapiens leucine rich repeat and
fibronectin type III domain containing 3 protein.
Length = 628
Score = 70.5 bits (165), Expect = 4e-12
Identities = 47/130 (36%), Positives = 66/130 (50%), Gaps = 1/130 (0%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
L LA N + ++ R L T L L+LS N + +A FADLRAL +DGN L L
Sbjct: 64 LRLADNFIASVRRRDLANMTGLLHLSLSRNTIRHVAAGAFADLRALRALHLDGNRLTSLG 123
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQG-ATSIRTLDLSYNRLAFAPDSLYSPLNQLH 33
+ GL NL + L NN+++ ++ A ++ LDLSYN L P + L +L
Sbjct: 124 EGQLRGLVNLRHLILSNNQLAALAAGALDDCAETLEDLDLSYNNLEQLP---WEALGRLG 180
Query: 32 KLQTLTLAWN 3
+ TL L N
Sbjct: 181 NVNTLGLDHN 190
Score = 68.5 bits (160), Expect = 2e-11
Identities = 50/166 (30%), Positives = 78/166 (46%), Gaps = 3/166 (1%)
Frame = -3
Query: 533 EIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRAL 357
E+++++N +++ +N+ L L L ++IR + F LR L L N+L +L
Sbjct: 63 ELRLADNFIASVRRRDLANMTGLLHLSLSRNTIRHVAAGAFADLRALRALHLDGNRLTSL 122
Query: 356 PRSVLRGQTQLTSLTLSYNAVAELAPELFADL-RALETFVMDGNELQVLPDSLFSGLRNL 180
LRG L L LS N +A LA D LE + N L+ LP L N+
Sbjct: 123 GEGQLRGLVNLRHLILSNNQLAALAAGALDDCAETLEDLDLSYNNLEQLPWEALGRLGNV 182
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL-AFAPDSLYSPL 45
T+ L +N ++ + F + LD++ NRL PD L+S L
Sbjct: 183 NTLGLDHNLLASVPAGAFSRLHKLARLDMTSNRLTTIPPDPLFSRL 228
>AY358127-1|AAQ88494.1| 627|Homo sapiens AILP5865 protein.
Length = 627
Score = 70.5 bits (165), Expect = 4e-12
Identities = 47/130 (36%), Positives = 66/130 (50%), Gaps = 1/130 (0%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
L LA N + ++ R L T L L+LS N + +A FADLRAL +DGN L L
Sbjct: 64 LRLADNFIASVRRRDLANMTGLLHLSLSRNTIRHVAAGAFADLRALRALHLDGNRLTSLG 123
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQG-ATSIRTLDLSYNRLAFAPDSLYSPLNQLH 33
+ GL NL + L NN+++ ++ A ++ LDLSYN L P + L +L
Sbjct: 124 EGQLRGLVNLRHLILSNNQLAALAAGALDDCAETLEDLDLSYNNLEQLP---WEALGRLG 180
Query: 32 KLQTLTLAWN 3
+ TL L N
Sbjct: 181 NVNTLGLDHN 190
>AL591063-1|CAI15264.1| 789|Homo sapiens RP11-535K1.2 protein.
Length = 789
Score = 70.5 bits (165), Expect = 4e-12
Identities = 50/164 (30%), Positives = 79/164 (48%), Gaps = 3/164 (1%)
Frame = -3
Query: 533 EIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRAL 357
E+++ N + + F+N+ L L L ++I + P F+ LR+L L N+L +L
Sbjct: 56 ELRLGGNFIIHISRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSL 115
Query: 356 PRSVLRGQTQLTSLTLSYNAVAELAPELFAD-LRALETFVMDGNELQVLPDSLFSGLRNL 180
LRG L L ++ N + +A E F D L LE + N L LP + NL
Sbjct: 116 GEDTLRGLVNLQHLIVNNNQLGGIADEAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNL 175
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL-AFAPDSLYS 51
+SL +N + I+ TF + LDL+ NRL PD +++
Sbjct: 176 HQLSLDHNLLDHIAEGTFADLQKLARLDLTSNRLQKLPPDPIFA 219
Score = 62.5 bits (145), Expect = 1e-09
Identities = 42/123 (34%), Positives = 62/123 (50%), Gaps = 2/123 (1%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
L L N + + R T L LTLS N ++ + P F DL +L + +D N L L
Sbjct: 57 LRLGGNFIIHISRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLG 116
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQG-ATSIRTLDLSYNRLAFAP-DSLYSPLNQL 36
+ GL NL + + NN++ I+ F+ ++ LDLSYN L P DS+ +N L
Sbjct: 117 EDTLRGLVNLQHLIVNNNQLGGIADEAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVN-L 175
Query: 35 HKL 27
H+L
Sbjct: 176 HQL 178
>AK172754-1|BAD18740.1| 628|Homo sapiens protein ( Homo sapiens
cDNA FLJ23915 fis, clone CAS06160. ).
Length = 628
Score = 70.5 bits (165), Expect = 4e-12
Identities = 47/130 (36%), Positives = 66/130 (50%), Gaps = 1/130 (0%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
L LA N + ++ R L T L L+LS N + +A FADLRAL +DGN L L
Sbjct: 64 LRLADNFIASVRRRDLANMTGLLHLSLSRNTIRHVAAGAFADLRALRALHLDGNRLTSLG 123
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQG-ATSIRTLDLSYNRLAFAPDSLYSPLNQLH 33
+ GL NL + L NN+++ ++ A ++ LDLSYN L P + L +L
Sbjct: 124 EGQLRGLVNLRHLILSNNQLAALAAGALDDCAETLEDLDLSYNNLEQLP---WEALGRLG 180
Query: 32 KLQTLTLAWN 3
+ TL L N
Sbjct: 181 NVNTLGLDHN 190
Score = 68.5 bits (160), Expect = 2e-11
Identities = 50/166 (30%), Positives = 78/166 (46%), Gaps = 3/166 (1%)
Frame = -3
Query: 533 EIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRAL 357
E+++++N +++ +N+ L L L ++IR + F LR L L N+L +L
Sbjct: 63 ELRLADNFIASVRRRDLANMTGLLHLSLSRNTIRHVAAGAFADLRALRALHLDGNRLTSL 122
Query: 356 PRSVLRGQTQLTSLTLSYNAVAELAPELFADL-RALETFVMDGNELQVLPDSLFSGLRNL 180
LRG L L LS N +A LA D LE + N L+ LP L N+
Sbjct: 123 GEGQLRGLVNLRHLILSNNQLAALAAGALDDCAETLEDLDLSYNNLEQLPWEALGRLGNV 182
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL-AFAPDSLYSPL 45
T+ L +N ++ + F + LD++ NRL PD L+S L
Sbjct: 183 NTLGLDHNLLASVPAGAFSRLHKLARLDMTSNRLTTIPPDPLFSRL 228
>AB033072-1|BAA86560.1| 832|Homo sapiens KIAA1246 protein protein.
Length = 832
Score = 70.5 bits (165), Expect = 4e-12
Identities = 50/164 (30%), Positives = 79/164 (48%), Gaps = 3/164 (1%)
Frame = -3
Query: 533 EIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRAL 357
E+++ N + + F+N+ L L L ++I + P F+ LR+L L N+L +L
Sbjct: 99 ELRLGGNFIIHISRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSL 158
Query: 356 PRSVLRGQTQLTSLTLSYNAVAELAPELFAD-LRALETFVMDGNELQVLPDSLFSGLRNL 180
LRG L L ++ N + +A E F D L LE + N L LP + NL
Sbjct: 159 GEDTLRGLVNLQHLIVNNNQLGGIADEAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNL 218
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL-AFAPDSLYS 51
+SL +N + I+ TF + LDL+ NRL PD +++
Sbjct: 219 HQLSLDHNLLDHIAEGTFADLQKLARLDLTSNRLQKLPPDPIFA 262
Score = 62.5 bits (145), Expect = 1e-09
Identities = 42/123 (34%), Positives = 62/123 (50%), Gaps = 2/123 (1%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
L L N + + R T L LTLS N ++ + P F DL +L + +D N L L
Sbjct: 100 LRLGGNFIIHISRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLG 159
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQG-ATSIRTLDLSYNRLAFAP-DSLYSPLNQL 36
+ GL NL + + NN++ I+ F+ ++ LDLSYN L P DS+ +N L
Sbjct: 160 EDTLRGLVNLQHLIVNNNQLGGIADEAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVN-L 218
Query: 35 HKL 27
H+L
Sbjct: 219 HQL 221
>AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein.
Length = 1534
Score = 70.5 bits (165), Expect = 4e-12
Identities = 44/154 (28%), Positives = 73/154 (47%), Gaps = 1/154 (0%)
Frame = -3
Query: 536 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRA 360
+ ++++ N + + F+ L LR LQL + I + F L L L RNQL
Sbjct: 64 ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHM 123
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
LP + + L+ L LS NA+ + + F L+ +D N++ + + F LR L
Sbjct: 124 LPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLRLDKNQISCIEEGAFRALRGL 183
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
++L NN I+ I +++F +RT L N L
Sbjct: 184 EVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 70.1 bits (164), Expect = 6e-12
Identities = 41/129 (31%), Positives = 67/129 (51%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
+ L N ++++P +L + LS N +AE+AP+ F LR+L + V+ GN++ LP
Sbjct: 314 IRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLP 373
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHK 30
+F GL L + L NKI+ I + FQ ++ L L N++ ++ L
Sbjct: 374 RGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFT---SLRA 430
Query: 29 LQTLTLAWN 3
+QTL LA N
Sbjct: 431 IQTLHLAQN 439
Score = 61.7 bits (143), Expect = 2e-09
Identities = 37/130 (28%), Positives = 62/130 (47%), Gaps = 1/130 (0%)
Frame = -3
Query: 389 LSLARNQLRALPRS-VLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVL 213
L L N++ L + + + T L + LS N V+E+ F ++ + N+L+ +
Sbjct: 545 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 604
Query: 212 PDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLH 33
+F GL L T+ LRNN+IS I ++F G ++R L L N++ + L L
Sbjct: 605 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 664
Query: 32 KLQTLTLAWN 3
L L +N
Sbjct: 665 TLNLLANPFN 674
Score = 60.5 bits (140), Expect = 4e-09
Identities = 36/139 (25%), Positives = 66/139 (47%)
Frame = -3
Query: 443 SSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFAD 264
+ ++ +P+ N+ L L N + + ++ G QL L L N + + F D
Sbjct: 50 TGLQAIPKNIPRNT--ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDD 107
Query: 263 LRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
++ LE ++ N+L +LP+ LF + L+ + L N I I F+GAT ++ L L N
Sbjct: 108 MKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLRLDKN 167
Query: 83 RLAFAPDSLYSPLNQLHKL 27
+++ + + L L L
Sbjct: 168 QISCIEEGAFRALRGLEVL 186
Score = 58.8 bits (136), Expect = 1e-08
Identities = 32/119 (26%), Positives = 60/119 (50%)
Frame = -3
Query: 440 SIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADL 261
SI E F + L+ ++L+ N++ + G ++ L L+ N + + +F L
Sbjct: 553 SILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGL 612
Query: 260 RALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
L T ++ N + + + F+GLRN+ +SL +N+I+ +S F S+ TL+L N
Sbjct: 613 DGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 671
Score = 56.4 bits (130), Expect = 7e-08
Identities = 29/103 (28%), Positives = 57/103 (55%)
Frame = -3
Query: 458 LQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAP 279
L LD + +P + + L+ + L+ N++ +L S +QLT+L LSYNA+ + P
Sbjct: 766 LYLDGNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPP 825
Query: 278 ELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKI 150
F LR+L + GN++ L + +F+ + +L+ +++ N +
Sbjct: 826 LAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPL 868
Score = 48.8 bits (111), Expect = 1e-05
Identities = 32/118 (27%), Positives = 56/118 (47%)
Frame = -3
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSL 201
+ LRALP+ + + +T L L N L P + + L+ + N++ L +S
Sbjct: 748 SNKHLRALPKGIPKN---VTELYLDGNQFT-LVPGQLSTFKYLQLVDLSNNKISSLSNSS 803
Query: 200 FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
F+ + LTT+ L N + I FQG S+R L L N ++ + +++ + L L
Sbjct: 804 FTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHL 861
Score = 47.2 bits (107), Expect = 4e-05
Identities = 24/90 (26%), Positives = 45/90 (50%), Gaps = 1/90 (1%)
Frame = -3
Query: 326 LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKIS 147
+T + L N + + P F+ R L + N++ + F GLR+L ++ L NKI+
Sbjct: 311 MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKIT 370
Query: 146 VISMNTFQGATSIRTLDLSYNRL-AFAPDS 60
+ F G +++ L L+ N++ PD+
Sbjct: 371 DLPRGVFGGLYTLQLLLLNANKINCIRPDA 400
Score = 39.5 bits (88), Expect = 0.009
Identities = 31/121 (25%), Positives = 52/121 (42%), Gaps = 1/121 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFI 411
N + + F ++ I +SNN + F L +L +L L + I +LP F
Sbjct: 319 NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFG 378
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L+ L L N++ + + L+ L+L N + LA F LRA++T +
Sbjct: 379 GLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQ 438
Query: 230 N 228
N
Sbjct: 439 N 439
Score = 39.1 bits (87), Expect = 0.012
Identities = 24/82 (29%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
Frame = -3
Query: 542 HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQL 366
++Q + +SNN +L + F+N+ L TL L ++++ +P F LR LSL N +
Sbjct: 785 YLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDI 844
Query: 365 RALPRSVLRGQTQLTSLTLSYN 300
L + T L+ L + N
Sbjct: 845 STLQEGIFADVTSLSHLAIGAN 866
Score = 33.1 bits (72), Expect = 0.77
Identities = 24/100 (24%), Positives = 43/100 (43%), Gaps = 1/100 (1%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PE 420
+ N ++ F G + E+ ++ N +++ +F L LRTL L + I + +
Sbjct: 572 LSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHND 631
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYN 300
F +R LSL NQ+ + L++L L N
Sbjct: 632 SFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 671
Score = 31.1 bits (67), Expect = 3.1
Identities = 44/202 (21%), Positives = 83/202 (41%), Gaps = 14/202 (6%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI-----REL 426
+N ++ FR L ++ + ++NN T+ + F+++P LRT +L + +
Sbjct: 166 KNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAW 225
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFAD------ 264
+++ P L + +L R + + Q + + S A P
Sbjct: 226 LSQWLRQRPTIGLFTQCSGPASL-RGLNVAEVQKSEFSCSGQGEAGRVPTCTLSSGSCPA 284
Query: 263 LRALETFVMD--GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLS 90
+ ++D G L +P +L +T + L N I I F +R +DLS
Sbjct: 285 MCTCSNGIVDCRGKGLTAIPANL---PETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLS 341
Query: 89 YNRLA-FAPDSLYSPLNQLHKL 27
N++A APD+ + L L+ L
Sbjct: 342 NNQIAEIAPDA-FQGLRSLNSL 362
>AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein.
Length = 1618
Score = 70.5 bits (165), Expect = 4e-12
Identities = 44/154 (28%), Positives = 73/154 (47%), Gaps = 1/154 (0%)
Frame = -3
Query: 536 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRA 360
+ ++++ N + + F+ L LR LQL + I + F L L L RNQL
Sbjct: 148 ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGVVERGAFDDMKELERLRLNRNQLHM 207
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
LP + + L+ L LS NA+ + + F L+ +D N++ + + F LR L
Sbjct: 208 LPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGL 267
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
++L NN I+ I +++F +RT L N L
Sbjct: 268 EVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 301
Score = 70.1 bits (164), Expect = 6e-12
Identities = 41/129 (31%), Positives = 67/129 (51%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
+ L N ++++P +L + LS N +AE+AP+ F LR+L + V+ GN++ LP
Sbjct: 398 IRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLP 457
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHK 30
+F GL L + L NKI+ I + FQ ++ L L N++ ++ L
Sbjct: 458 RGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFT---SLRA 514
Query: 29 LQTLTLAWN 3
+QTL LA N
Sbjct: 515 IQTLHLAQN 523
Score = 61.7 bits (143), Expect = 2e-09
Identities = 37/130 (28%), Positives = 62/130 (47%), Gaps = 1/130 (0%)
Frame = -3
Query: 389 LSLARNQLRALPRS-VLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVL 213
L L N++ L + + + T L + LS N V+E+ F ++ + N+L+ +
Sbjct: 629 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 688
Query: 212 PDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLH 33
+F GL L T+ LRNN+IS I ++F G ++R L L N++ + L L
Sbjct: 689 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 748
Query: 32 KLQTLTLAWN 3
L L +N
Sbjct: 749 TLNLLANPFN 758
Score = 60.9 bits (141), Expect = 3e-09
Identities = 36/139 (25%), Positives = 66/139 (47%)
Frame = -3
Query: 443 SSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFAD 264
+ ++ +P+ N+ L L N + + ++ G QL L L N + + F D
Sbjct: 134 TGLQAIPKNIPRNT--ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGVVERGAFDD 191
Query: 263 LRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
++ LE ++ N+L +LP+ LF + L+ + L N I I F+GAT ++ L L N
Sbjct: 192 MKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKN 251
Query: 83 RLAFAPDSLYSPLNQLHKL 27
+++ + + L L L
Sbjct: 252 QISCIEEGAFRALRGLEVL 270
Score = 58.8 bits (136), Expect = 1e-08
Identities = 32/119 (26%), Positives = 60/119 (50%)
Frame = -3
Query: 440 SIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADL 261
SI E F + L+ ++L+ N++ + G ++ L L+ N + + +F L
Sbjct: 637 SILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGL 696
Query: 260 RALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
L T ++ N + + + F+GLRN+ +SL +N+I+ +S F S+ TL+L N
Sbjct: 697 DGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 755
Score = 56.4 bits (130), Expect = 7e-08
Identities = 29/103 (28%), Positives = 57/103 (55%)
Frame = -3
Query: 458 LQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAP 279
L LD + +P + + L+ + L+ N++ +L S +QLT+L LSYNA+ + P
Sbjct: 850 LYLDGNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPP 909
Query: 278 ELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKI 150
F LR+L + GN++ L + +F+ + +L+ +++ N +
Sbjct: 910 LAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPL 952
Score = 48.8 bits (111), Expect = 1e-05
Identities = 32/118 (27%), Positives = 56/118 (47%)
Frame = -3
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSL 201
+ LRALP+ + + +T L L N L P + + L+ + N++ L +S
Sbjct: 832 SNKHLRALPKGIPKN---VTELYLDGNQFT-LVPGQLSTFKYLQLVDLSNNKISSLSNSS 887
Query: 200 FSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
F+ + LTT+ L N + I FQG S+R L L N ++ + +++ + L L
Sbjct: 888 FTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHL 945
Score = 47.2 bits (107), Expect = 4e-05
Identities = 24/90 (26%), Positives = 45/90 (50%), Gaps = 1/90 (1%)
Frame = -3
Query: 326 LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKIS 147
+T + L N + + P F+ R L + N++ + F GLR+L ++ L NKI+
Sbjct: 395 MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKIT 454
Query: 146 VISMNTFQGATSIRTLDLSYNRL-AFAPDS 60
+ F G +++ L L+ N++ PD+
Sbjct: 455 DLPRGVFGGLYTLQLLLLNANKINCIRPDA 484
Score = 39.5 bits (88), Expect = 0.009
Identities = 31/121 (25%), Positives = 52/121 (42%), Gaps = 1/121 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFI 411
N + + F ++ I +SNN + F L +L +L L + I +LP F
Sbjct: 403 NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFG 462
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L+ L L N++ + + L+ L+L N + LA F LRA++T +
Sbjct: 463 GLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQ 522
Query: 230 N 228
N
Sbjct: 523 N 523
Score = 39.1 bits (87), Expect = 0.012
Identities = 24/82 (29%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
Frame = -3
Query: 542 HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQL 366
++Q + +SNN +L + F+N+ L TL L ++++ +P F LR LSL N +
Sbjct: 869 YLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDI 928
Query: 365 RALPRSVLRGQTQLTSLTLSYN 300
L + T L+ L + N
Sbjct: 929 STLQEGIFADVTSLSHLAIGAN 950
Score = 33.1 bits (72), Expect = 0.77
Identities = 24/100 (24%), Positives = 43/100 (43%), Gaps = 1/100 (1%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PE 420
+ N ++ F G + E+ ++ N +++ +F L LRTL L + I + +
Sbjct: 656 LSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHND 715
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYN 300
F +R LSL NQ+ + L++L L N
Sbjct: 716 SFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 755
Score = 31.1 bits (67), Expect = 3.1
Identities = 44/202 (21%), Positives = 83/202 (41%), Gaps = 14/202 (6%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI-----REL 426
+N ++ FR L ++ + ++NN T+ + F+++P LRT +L + +
Sbjct: 250 KNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAW 309
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFAD------ 264
+++ P L + +L R + + Q + + S A P
Sbjct: 310 LSQWLRQRPTIGLFTQCSGPASL-RGLNVAEVQKSEFSCSGQGEAGRVPTCTLSSGSCPA 368
Query: 263 LRALETFVMD--GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLS 90
+ ++D G L +P +L +T + L N I I F +R +DLS
Sbjct: 369 MCTCSNGIVDCRGKGLTAIPANL---PETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLS 425
Query: 89 YNRLA-FAPDSLYSPLNQLHKL 27
N++A APD+ + L L+ L
Sbjct: 426 NNQIAEIAPDA-FQGLRSLNSL 446
>BC129927-1|AAI29928.1| 1323|Homo sapiens PH domain and leucine rich
repeat protein phosphatase-like protein.
Length = 1323
Score = 70.1 bits (164), Expect = 6e-12
Identities = 55/181 (30%), Positives = 90/181 (49%), Gaps = 4/181 (2%)
Frame = -3
Query: 539 IQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRA 360
++ + +S+N L L + + L L L + +LP + + L+TL L N L
Sbjct: 301 LKGLNLSHN-KLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTT 359
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
LP L QL+SL +S+N +++ PE++ L L+ VM GN L+VL + + + ++
Sbjct: 360 LPEE-LGNLQQLSSLGISFNNFSQI-PEVYEKLTMLDRVVMAGNCLEVLNLGVLNRMNHI 417
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLH----KLQTLTL 12
V LR N + + + +G I +DL NRL S L QLH +L+ LTL
Sbjct: 418 KHVDLRMNHLKTMVIENLEGNKHITHVDLRDNRLTDLDLSSLCSLEQLHCGRNQLRELTL 477
Query: 11 A 9
+
Sbjct: 478 S 478
Score = 52.0 bits (119), Expect = 2e-06
Identities = 52/187 (27%), Positives = 86/187 (45%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N + + E G HI + + +N L + S+L +L L + +REL +S
Sbjct: 425 NHLKTMVIENLEGNKHITHVDLRDN---RLTDLDLSSLCSLEQLHCGRNQLRELT---LS 478
Query: 407 NSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 228
LRTL + N+L A+ +V + LT L LS N + E P+ + + +E + N
Sbjct: 479 GFSLRTLYASSNRLTAV--NVYPVPSLLTFLDLSRNLL-ECVPDWACEAKKIEVLDVSYN 535
Query: 227 ELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSP 48
L +P + S L +L + L +N + ++ T + LDL +N L PD+L+S
Sbjct: 536 LLTEVPVRILSSL-SLRKLMLGHNHVQ--NLPTLVEHIPLEVLDLQHNALTRLPDTLFSK 592
Query: 47 LNQLHKL 27
L L
Sbjct: 593 ALNLRYL 599
Score = 48.4 bits (110), Expect = 2e-05
Identities = 39/144 (27%), Positives = 62/144 (43%), Gaps = 4/144 (2%)
Frame = -3
Query: 467 LRTLQLDLSSIRELPEEFISNS-PLRTLSLARNQLRALPRSVLRGQTQLTSLTLSY---N 300
L L L +++ LP+ S + LR L+ + N L +LP S G+ L+ L L Y N
Sbjct: 572 LEVLDLQHNALTRLPDTLFSKALNLRYLNASANSLESLP-SACTGEESLSMLQLLYLTNN 630
Query: 299 AVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQG 120
+ + + L + N+LQ P S + L L ++L NK+ I T
Sbjct: 631 LLTDQCIPVLVGHLHLRILHLANNQLQTFPASKLNKLEQLEELNLSGNKLKTIP-TTIAN 689
Query: 119 ATSIRTLDLSYNRLAFAPDSLYSP 48
+ TL N ++ P+ L P
Sbjct: 690 CKRLHTLVAHSNNISIFPEILQLP 713
>BC035267-1|AAH35267.1| 723|Homo sapiens PHLPPL protein protein.
Length = 723
Score = 70.1 bits (164), Expect = 6e-12
Identities = 55/181 (30%), Positives = 90/181 (49%), Gaps = 4/181 (2%)
Frame = -3
Query: 539 IQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRA 360
++ + +S+N L L + + L L L + +LP + + L+TL L N L
Sbjct: 39 LKGLNLSHN-KLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTT 97
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
LP L QL+SL +S+N +++ PE++ L L+ VM GN L+VL + + + ++
Sbjct: 98 LPEE-LGNLQQLSSLGISFNNFSQI-PEVYEKLTMLDRVVMAGNCLEVLNLGVLNRMNHI 155
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLH----KLQTLTL 12
V LR N + + + +G I +DL NRL S L QLH +L+ LTL
Sbjct: 156 KHVDLRMNHLKTMVIENLEGNKHITHVDLRDNRLTDLDLSSLCSLEQLHCGRNQLRELTL 215
Query: 11 A 9
+
Sbjct: 216 S 216
Score = 52.0 bits (119), Expect = 2e-06
Identities = 52/187 (27%), Positives = 86/187 (45%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N + + E G HI + + +N L + S+L +L L + +REL +S
Sbjct: 163 NHLKTMVIENLEGNKHITHVDLRDN---RLTDLDLSSLCSLEQLHCGRNQLRELT---LS 216
Query: 407 NSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 228
LRTL + N+L A+ +V + LT L LS N + E P+ + + +E + N
Sbjct: 217 GFSLRTLYASSNRLTAV--NVYPVPSLLTFLDLSRNLL-ECVPDWACEAKKIEVLDVSYN 273
Query: 227 ELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSP 48
L +P + S L +L + L +N + ++ T + LDL +N L PD+L+S
Sbjct: 274 LLTEVPVRILSSL-SLRKLMLGHNHVQ--NLPTLVEHIPLEVLDLQHNALTRLPDTLFSK 330
Query: 47 LNQLHKL 27
L L
Sbjct: 331 ALNLRYL 337
Score = 48.4 bits (110), Expect = 2e-05
Identities = 39/144 (27%), Positives = 62/144 (43%), Gaps = 4/144 (2%)
Frame = -3
Query: 467 LRTLQLDLSSIRELPEEFISNS-PLRTLSLARNQLRALPRSVLRGQTQLTSLTLSY---N 300
L L L +++ LP+ S + LR L+ + N L +LP S G+ L+ L L Y N
Sbjct: 310 LEVLDLQHNALTRLPDTLFSKALNLRYLNASANSLESLP-SACTGEESLSMLQLLYLTNN 368
Query: 299 AVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQG 120
+ + + L + N+LQ P S + L L ++L NK+ I T
Sbjct: 369 LLTDQCIPVLVGHLHLRILRLANNQLQTFPASKLNKLEQLEELNLSGNKLKTIP-TTIAN 427
Query: 119 ATSIRTLDLSYNRLAFAPDSLYSP 48
+ TL N ++ P+ L P
Sbjct: 428 CKRLHTLVAHSNNISIFPEILQLP 451
>AB040917-1|BAA96008.1| 700|Homo sapiens KIAA1484 protein protein.
Length = 700
Score = 70.1 bits (164), Expect = 6e-12
Identities = 46/128 (35%), Positives = 62/128 (48%), Gaps = 1/128 (0%)
Frame = -3
Query: 383 LARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDS 204
L N + A+ R T L LTLS N + ++A FADLRAL +D N L +
Sbjct: 1 LTDNFIAAVRRRDFANMTSLVHLTLSRNTIGQVAAGAFADLRALRALHLDSNRLAEVRGD 60
Query: 203 LFSGLRNLTTVSLRNNKISVISMNTFQG-ATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
GL NL + L NN+I + F +++ LDLSYN L P + + Q+ L
Sbjct: 61 QLRGLGNLRHLILGNNQIRRVESAAFDAFLSTVEDLDLSYNNLEALP---WEAVGQMVNL 117
Query: 26 QTLTLAWN 3
TLTL N
Sbjct: 118 NTLTLDHN 125
Score = 57.2 bits (132), Expect = 4e-08
Identities = 46/160 (28%), Positives = 74/160 (46%), Gaps = 3/160 (1%)
Frame = -3
Query: 524 ISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRALPRS 348
+++N ++ F+N+ +L L L ++I ++ F LR L L N+L +
Sbjct: 1 LTDNFIAAVRRRDFANMTSLVHLTLSRNTIGQVAAGAFADLRALRALHLDSNRLAEVRGD 60
Query: 347 VLRGQTQLTSLTLSYNAVAELAPELF-ADLRALETFVMDGNELQVLPDSLFSGLRNLTTV 171
LRG L L L N + + F A L +E + N L+ LP + NL T+
Sbjct: 61 QLRGLGNLRHLILGNNQIRRVESAAFDAFLSTVEDLDLSYNNLEALPWEAVGQMVNLNTL 120
Query: 170 SLRNNKISVISMNTFQGATSIRTLDLSYNRL-AFAPDSLY 54
+L +N I I+ TF + LD++ NRL PD L+
Sbjct: 121 TLDHNLIDHIAEGTFVQLHKLVRLDMTSNRLHKLPPDGLF 160
Score = 47.6 bits (108), Expect = 3e-05
Identities = 38/137 (27%), Positives = 58/137 (42%), Gaps = 3/137 (2%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE 420
T+ RN+ + + F L ++ + + +N ++ L LR L L + IR +
Sbjct: 24 TLSRNTIGQVAAGAFADLRALRALHLDSNRLAEVRGDQLRGLGNLRHLILGNNQIRRVES 83
Query: 419 EFISN--SPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALET 246
S + L L+ N L ALP + L +LTL +N + +A F L L
Sbjct: 84 AAFDAFLSTVEDLDLSYNNLEALPWEAVGQMVNLNTLTLDHNLIDHIAEGTFVQLHKLVR 143
Query: 245 FVMDGNELQVL-PDSLF 198
M N L L PD LF
Sbjct: 144 LDMTSNRLHKLPPDGLF 160
>AB023148-1|BAA76775.2| 1258|Homo sapiens KIAA0931 protein protein.
Length = 1258
Score = 70.1 bits (164), Expect = 6e-12
Identities = 55/181 (30%), Positives = 90/181 (49%), Gaps = 4/181 (2%)
Frame = -3
Query: 539 IQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRA 360
++ + +S+N L L + + L L L + +LP + + L+TL L N L
Sbjct: 303 LKGLNLSHN-KLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTT 361
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
LP L QL+SL +S+N +++ PE++ L L+ VM GN L+VL + + + ++
Sbjct: 362 LPEE-LGNLQQLSSLGISFNNFSQI-PEVYEKLTMLDRVVMAGNCLEVLNLGVLNRMNHI 419
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLH----KLQTLTL 12
V LR N + + + +G I +DL NRL S L QLH +L+ LTL
Sbjct: 420 KHVDLRMNHLKTMVIENLEGNKHITHVDLRDNRLTDLDLSSLCSLEQLHCGRNQLRELTL 479
Query: 11 A 9
+
Sbjct: 480 S 480
Score = 58.8 bits (136), Expect = 1e-08
Identities = 56/191 (29%), Positives = 93/191 (48%), Gaps = 1/191 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N + + E G HI + + +N L + S+L +L L + +REL +S
Sbjct: 427 NHLKTMVIENLEGNKHITHVDLRDN---RLTDLDLSSLCSLEQLHCGRNQLRELT---LS 480
Query: 407 NSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 228
LRTL + N+L A+ +V + LT L LS N + E P+ + + +E + N
Sbjct: 481 GFSLRTLYASSNRLTAV--NVYPVPSLLTFLDLSRNLL-ECVPDWACEAKKIEVLDVSYN 537
Query: 227 ELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS- 51
L +P + S L +L + L +N + ++ T + LDL +N L PD+L+S
Sbjct: 538 LLTEVPVRILSSL-SLRKLMLGHNHVQ--NLPTLVEHIPLEVLDLQHNALTRLPDTLFSK 594
Query: 50 PLNQLHKLQTL 18
LN+L+KL+ L
Sbjct: 595 ALNKLNKLEQL 605
>U96769-1|AAC13410.1| 359|Homo sapiens chondroadherin protein.
Length = 359
Score = 69.7 bits (163), Expect = 7e-12
Identities = 47/146 (32%), Positives = 70/146 (47%), Gaps = 1/146 (0%)
Frame = -3
Query: 557 FRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSL 381
FRGL + + +S+N ++ F +L L L LD + + ELP +S L L L
Sbjct: 95 FRGLKQLIYLYLSHNDIRVVRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQL 154
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSL 201
N++R L +G L L LS NA++ L P D+ L F +D N+L P +
Sbjct: 155 NNNKIRELRAGPFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAA 214
Query: 200 FSGLRNLTTVSLRNNKISVISMNTFQ 123
S LR + + L +N + I N FQ
Sbjct: 215 LSKLRVVEELKLSHNPLKSIPDNAFQ 240
Score = 64.9 bits (151), Expect = 2e-10
Identities = 41/108 (37%), Positives = 54/108 (50%)
Frame = -3
Query: 398 LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 219
L +L L Q+R + RG QL L LS+N + + F DL L +D N++
Sbjct: 77 LVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVVRAGAFDDLTELTYLYLDHNKVT 136
Query: 218 VLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLA 75
LP L S L NL + L NNKI + FQGA +R L LS N L+
Sbjct: 137 ELPRGLLSPLVNLFILQLNNNKIRELRAGPFQGAKDLRWLYLSENALS 184
Score = 54.4 bits (125), Expect = 3e-07
Identities = 48/196 (24%), Positives = 78/196 (39%), Gaps = 1/196 (0%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE- 420
+ RN+F L + FR + ++ + + + + F L L L L + IR +
Sbjct: 58 LQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVVRAG 117
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
F + L L L N++ LPR +L L L L+ N + EL F + L
Sbjct: 118 AFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGPFQGAKDLRWLY 177
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
+ N L L + NL + N++S + L LS+N L PD+
Sbjct: 178 LSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDN 237
Query: 59 LYSPLNQLHKLQTLTL 12
+ + L+TL L
Sbjct: 238 AFQSFGRY--LETLWL 251
Score = 53.2 bits (122), Expect = 7e-07
Identities = 42/151 (27%), Positives = 66/151 (43%), Gaps = 2/151 (1%)
Frame = -3
Query: 530 IKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRALP 354
++++NN L+ F LR L L +++ L P L + RNQL + P
Sbjct: 152 LQLNNNKIRELRAGPFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYP 211
Query: 353 RSVLRGQTQLTSLTLSYNAVAELAPELFADL-RALETFVMDGNELQVLPDSLFSGLRNLT 177
+ L + L LS+N + + F R LET +D L+ D F G+ L
Sbjct: 212 SAALSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLK 271
Query: 176 TVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
V L NN+++ + N S+ TL L+ N
Sbjct: 272 HVHLENNRLNQLPSNF--PFDSLETLALTNN 300
>BC068558-1|AAH68558.1| 614|Homo sapiens LINGO1 protein protein.
Length = 614
Score = 69.7 bits (163), Expect = 7e-12
Identities = 38/123 (30%), Positives = 65/123 (52%)
Frame = -3
Query: 395 RTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 216
R L L +N+++ L + L L L+ N V+ + P F +L L T + N L++
Sbjct: 68 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKL 127
Query: 215 LPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQL 36
+P +F+GL NLT + + NKI ++ FQ ++R+L++ N L + +S LN L
Sbjct: 128 IPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLRSLEVGDNDLVYISHRAFSGLNSL 187
Query: 35 HKL 27
+L
Sbjct: 188 EQL 190
Score = 66.1 bits (154), Expect = 9e-11
Identities = 41/169 (24%), Positives = 84/169 (49%), Gaps = 1/169 (0%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP-EEF 414
+N + L+ + F H++E++++ N+ ++ F+NL LRTL L + ++ +P F
Sbjct: 74 KNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVF 133
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
S L L ++ N++ L + + L SL + N + ++ F+ L +LE ++
Sbjct: 134 TGLSNLTKLDISENKIVILLDYMFQDLYNLRSLEVGDNDLVYISHRAFSGLNSLEQLTLE 193
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSY 87
L +P S L L + LR+ I+ I +F+ ++ L++S+
Sbjct: 194 KCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISH 242
Score = 63.7 bits (148), Expect = 5e-10
Identities = 45/170 (26%), Positives = 78/170 (45%), Gaps = 1/170 (0%)
Frame = -3
Query: 530 IKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRALP 354
+ + N TL + F++ P L L+L+ + + + P F + LRTL L N+L+ +P
Sbjct: 70 LDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIP 129
Query: 353 RSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTT 174
V G + LT L +S N + L +F DL L + + N+L + FSGL +L
Sbjct: 130 LGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLRSLEVGDNDLVYISHRAFSGLNSLEQ 189
Query: 173 VSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
++L ++ I + L L + + D + L +L L+
Sbjct: 190 LTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLE 239
Score = 58.4 bits (135), Expect = 2e-08
Identities = 34/134 (25%), Positives = 64/134 (47%)
Frame = -3
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALET 246
P + ++ R + R + A+P + T+ L L N + L + FA LE
Sbjct: 37 PPRYECSAQDRAVLCHRKRFVAVPEGI---PTETRLLDLGKNRIKTLNQDEFASFPHLEE 93
Query: 245 FVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAP 66
++ N + + F+ L NL T+ LR+N++ +I + F G +++ LD+S N++
Sbjct: 94 LELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILL 153
Query: 65 DSLYSPLNQLHKLQ 24
D ++ L L L+
Sbjct: 154 DYMFQDLYNLRSLE 167
Score = 56.0 bits (129), Expect = 1e-07
Identities = 47/192 (24%), Positives = 94/192 (48%), Gaps = 4/192 (2%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N + + +F GL ++ ++ IS N + L + +F +L LR+L++ + + + S
Sbjct: 123 NRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLRSLEVGDNDLVYISHRAFS 182
Query: 407 N-SPLRTLSLARNQLRALPR---SVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+ L L+L + L ++P S L G L L+ NA+ + + + L+ LE +
Sbjct: 183 GLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLE--I 240
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
L + + GL NLT++S+ + ++ + + +R L+LSYNR++ S
Sbjct: 241 SHWPYLDTMTPNCLYGL-NLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNRISTIEGS 299
Query: 59 LYSPLNQLHKLQ 24
+ L +L ++Q
Sbjct: 300 MLHELLRLQEIQ 311
Score = 53.2 bits (122), Expect = 7e-07
Identities = 30/108 (27%), Positives = 53/108 (49%)
Frame = -3
Query: 398 LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 219
L +LS+ L A+P +R L L LSYN ++ + + +L L+ + G +L
Sbjct: 259 LTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNRISTIEGSMLHELLRLQEIQLVGGQLA 318
Query: 218 VLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLA 75
V+ F GL L +++ N+++ + + F ++ TL L N LA
Sbjct: 319 VVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPLA 366
>AY358115-1|AAQ88482.1| 593|Homo sapiens DAAT9248 protein.
Length = 593
Score = 69.3 bits (162), Expect = 1e-11
Identities = 47/132 (35%), Positives = 70/132 (53%), Gaps = 2/132 (1%)
Frame = -3
Query: 401 PLRT--LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 228
PL T L L+ N+L L + +L + L L LSYN ++ L P F L++L T + GN
Sbjct: 59 PLDTELLDLSGNRLWGLQQGMLSRLSLLQELDLSYNQLSTLEPGAFHGLQSLLTLRLQGN 118
Query: 227 ELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSP 48
L+++ +FSGL LT + LR N+I + F S++ L++ N L F ++
Sbjct: 119 RLRIMGPGVFSGLSALTLLDLRLNQIVLFLDGAFGELGSLQKLEVGDNHLVFVAPGAFA- 177
Query: 47 LNQLHKLQTLTL 12
L KL TLTL
Sbjct: 178 --GLAKLSTLTL 187
Score = 50.4 bits (115), Expect = 5e-06
Identities = 46/190 (24%), Positives = 80/190 (42%), Gaps = 2/190 (1%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL-DLSSIRELPEEFI 411
N R + +F GL + + + N + + F L +L+ L++ D + P F
Sbjct: 118 NRLRIMGPGVFSGLSALTLLDLRLNQIVLFLDGAFGELGSLQKLEVGDNHLVFVAPGAFA 177
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD- 234
+ L TL+L R L +P L L +L L + L L L+ +
Sbjct: 178 GLAKLSTLTLERCNLSTVPGLALARLPALVALRLRELDIGRLPAGALRGLGQLKELEIHL 237
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
L+ L GL NL+++++ +S + + +R LDLS N ++ P
Sbjct: 238 WPSLEALDPGSLVGL-NLSSLAITRCNLSSVPFQALYHLSFLRVLDLSQNPISAIPARRL 296
Query: 53 SPLNQLHKLQ 24
SPL +L +L+
Sbjct: 297 SPLVRLQELR 306
>AL589765-16|CAI17178.1| 593|Homo sapiens leucine rich repeat and
Ig domain containing 4 protein.
Length = 593
Score = 69.3 bits (162), Expect = 1e-11
Identities = 47/132 (35%), Positives = 70/132 (53%), Gaps = 2/132 (1%)
Frame = -3
Query: 401 PLRT--LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 228
PL T L L+ N+L L + +L + L L LSYN ++ L P F L++L T + GN
Sbjct: 59 PLDTELLDLSGNRLWGLQQGMLSRLSLLQELDLSYNQLSTLEPGAFHGLQSLLTLRLQGN 118
Query: 227 ELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSP 48
L+++ +FSGL LT + LR N+I + F S++ L++ N L F ++
Sbjct: 119 RLRIMGPGVFSGLSALTLLDLRLNQIVLFLDGAFGELGSLQKLEVGDNHLVFVAPGAFA- 177
Query: 47 LNQLHKLQTLTL 12
L KL TLTL
Sbjct: 178 --GLAKLSTLTL 187
Score = 50.4 bits (115), Expect = 5e-06
Identities = 46/190 (24%), Positives = 80/190 (42%), Gaps = 2/190 (1%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL-DLSSIRELPEEFI 411
N R + +F GL + + + N + + F L +L+ L++ D + P F
Sbjct: 118 NRLRIMGPGVFSGLSALTLLDLRLNQIVLFLDGAFGELGSLQKLEVGDNHLVFVAPGAFA 177
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD- 234
+ L TL+L R L +P L L +L L + L L L+ +
Sbjct: 178 GLAKLSTLTLERCNLSTVPGLALARLPALVALRLRELDIGRLPAGALRGLGQLKELEIHL 237
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
L+ L GL NL+++++ +S + + +R LDLS N ++ P
Sbjct: 238 WPSLEALDPGSLVGL-NLSSLAITRCNLSSVPFQALYHLSFLRVLDLSQNPISAIPARRL 296
Query: 53 SPLNQLHKLQ 24
SPL +L +L+
Sbjct: 297 SPLVRLQELR 306
>CR456360-1|CAG30246.1| 473|Homo sapiens Em:AC007663.1 protein.
Length = 473
Score = 68.9 bits (161), Expect = 1e-11
Identities = 45/125 (36%), Positives = 62/125 (49%), Gaps = 1/125 (0%)
Frame = -3
Query: 398 LRTLSLARN-QLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 222
L L L+ N QLR++ + G +L +L L + EL P LF L AL+ + N L
Sbjct: 107 LEQLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNAL 166
Query: 221 QVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLN 42
Q LPD F L NLT + L N+IS + F+G S+ L L NR+A + L
Sbjct: 167 QALPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLG 226
Query: 41 QLHKL 27
+L L
Sbjct: 227 RLMTL 231
Score = 39.9 bits (89), Expect = 0.007
Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Frame = -3
Query: 257 ALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN-R 81
A + + GN + +P + F RNLT + L +N ++ I F G + LDLS N +
Sbjct: 58 ASQRIFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQ 117
Query: 80 LAFAPDSLYSPLNQLHKL 27
L + + L +LH L
Sbjct: 118 LRSVDPATFHGLGRLHTL 135
>BC071866-1|AAH71866.1| 460|Homo sapiens LRFN4 protein protein.
Length = 460
Score = 68.9 bits (161), Expect = 1e-11
Identities = 53/164 (32%), Positives = 79/164 (48%), Gaps = 3/164 (1%)
Frame = -3
Query: 533 EIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRAL 357
E+++++N L F N+ L L L ++I + F LR+L L N+L L
Sbjct: 52 ELRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVEL 111
Query: 356 PRSVLRGQTQLTSLTLSYNAVAELAPELFAD-LRALETFVMDGNELQVLPDSLFSGLRNL 180
LRG L L LS N + +AP F D L +LE + N L+ +P + + L
Sbjct: 112 GTGSLRGPVNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPAL 171
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLA-FAPDSLYS 51
T++L +N I + F + LDL+ NRLA APD L+S
Sbjct: 172 HTLNLDHNLIDALPPGAFAQLGQLSRLDLTSNRLATLAPDPLFS 215
Score = 64.5 bits (150), Expect = 3e-10
Identities = 43/122 (35%), Positives = 57/122 (46%), Gaps = 1/122 (0%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
L LA N ++AL R T L LTLS NA+ + F DL +L + +DGN L L
Sbjct: 53 LRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELG 112
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQG-ATSIRTLDLSYNRLAFAPDSLYSPLNQLH 33
G NL + L N++ I+ F S+ LDLSYN L P + + LH
Sbjct: 113 TGSLRGPVNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALH 172
Query: 32 KL 27
L
Sbjct: 173 TL 174
>BC015581-1|AAH15581.2| 635|Homo sapiens leucine rich repeat and
fibronectin type III domain containing 4 protein.
Length = 635
Score = 68.9 bits (161), Expect = 1e-11
Identities = 53/164 (32%), Positives = 79/164 (48%), Gaps = 3/164 (1%)
Frame = -3
Query: 533 EIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRAL 357
E+++++N L F N+ L L L ++I + F LR+L L N+L L
Sbjct: 52 ELRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVEL 111
Query: 356 PRSVLRGQTQLTSLTLSYNAVAELAPELFAD-LRALETFVMDGNELQVLPDSLFSGLRNL 180
LRG L L LS N + +AP F D L +LE + N L+ +P + + L
Sbjct: 112 GTGSLRGPVNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPAL 171
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLA-FAPDSLYS 51
T++L +N I + F + LDL+ NRLA APD L+S
Sbjct: 172 HTLNLDHNLIDALPPGAFAQLGQLSRLDLTSNRLATLAPDPLFS 215
Score = 64.5 bits (150), Expect = 3e-10
Identities = 43/122 (35%), Positives = 57/122 (46%), Gaps = 1/122 (0%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
L LA N ++AL R T L LTLS NA+ + F DL +L + +DGN L L
Sbjct: 53 LRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELG 112
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQG-ATSIRTLDLSYNRLAFAPDSLYSPLNQLH 33
G NL + L N++ I+ F S+ LDLSYN L P + + LH
Sbjct: 113 TGSLRGPVNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALH 172
Query: 32 KL 27
L
Sbjct: 173 TL 174
>BC011787-1|AAH11787.1| 473|Homo sapiens reticulon 4 receptor
protein.
Length = 473
Score = 68.9 bits (161), Expect = 1e-11
Identities = 45/125 (36%), Positives = 62/125 (49%), Gaps = 1/125 (0%)
Frame = -3
Query: 398 LRTLSLARN-QLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 222
L L L+ N QLR++ + G +L +L L + EL P LF L AL+ + N L
Sbjct: 107 LEQLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNAL 166
Query: 221 QVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLN 42
Q LPD F L NLT + L N+IS + F+G S+ L L NR+A + L
Sbjct: 167 QALPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLG 226
Query: 41 QLHKL 27
+L L
Sbjct: 227 RLMTL 231
Score = 39.9 bits (89), Expect = 0.007
Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Frame = -3
Query: 257 ALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN-R 81
A + + GN + +P + F RNLT + L +N ++ I F G + LDLS N +
Sbjct: 58 ASQRIFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQ 117
Query: 80 LAFAPDSLYSPLNQLHKL 27
L + + L +LH L
Sbjct: 118 LRSVDPATFHGLGRLHTL 135
>BC007718-1|AAH07718.1| 541|Homo sapiens LRFN4 protein protein.
Length = 541
Score = 68.9 bits (161), Expect = 1e-11
Identities = 53/164 (32%), Positives = 79/164 (48%), Gaps = 3/164 (1%)
Frame = -3
Query: 533 EIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRAL 357
E+++++N L F N+ L L L ++I + F LR+L L N+L L
Sbjct: 52 ELRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVEL 111
Query: 356 PRSVLRGQTQLTSLTLSYNAVAELAPELFAD-LRALETFVMDGNELQVLPDSLFSGLRNL 180
LRG L L LS N + +AP F D L +LE + N L+ +P + + L
Sbjct: 112 GTGSLRGPVNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPAL 171
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLA-FAPDSLYS 51
T++L +N I + F + LDL+ NRLA APD L+S
Sbjct: 172 HTLNLDHNLIDALPPGAFAQLGQLSRLDLTSNRLATLAPDPLFS 215
Score = 64.5 bits (150), Expect = 3e-10
Identities = 43/122 (35%), Positives = 57/122 (46%), Gaps = 1/122 (0%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
L LA N ++AL R T L LTLS NA+ + F DL +L + +DGN L L
Sbjct: 53 LRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELG 112
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQG-ATSIRTLDLSYNRLAFAPDSLYSPLNQLH 33
G NL + L N++ I+ F S+ LDLSYN L P + + LH
Sbjct: 113 TGSLRGPVNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALH 172
Query: 32 KL 27
L
Sbjct: 173 TL 174
>AY358297-1|AAQ88664.1| 473|Homo sapiens NOGOR protein.
Length = 473
Score = 68.9 bits (161), Expect = 1e-11
Identities = 45/125 (36%), Positives = 62/125 (49%), Gaps = 1/125 (0%)
Frame = -3
Query: 398 LRTLSLARN-QLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 222
L L L+ N QLR++ + G +L +L L + EL P LF L AL+ + N L
Sbjct: 107 LEQLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNAL 166
Query: 221 QVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLN 42
Q LPD F L NLT + L N+IS + F+G S+ L L NR+A + L
Sbjct: 167 QALPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLG 226
Query: 41 QLHKL 27
+L L
Sbjct: 227 RLMTL 231
Score = 39.9 bits (89), Expect = 0.007
Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Frame = -3
Query: 257 ALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN-R 81
A + + GN + +P + F RNLT + L +N ++ I F G + LDLS N +
Sbjct: 58 ASQRIFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQ 117
Query: 80 LAFAPDSLYSPLNQLHKL 27
L + + L +LH L
Sbjct: 118 LRSVDPATFHGLGRLHTL 135
>AF283463-1|AAG53612.1| 473|Homo sapiens Nogo receptor protein.
Length = 473
Score = 68.9 bits (161), Expect = 1e-11
Identities = 45/125 (36%), Positives = 62/125 (49%), Gaps = 1/125 (0%)
Frame = -3
Query: 398 LRTLSLARN-QLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 222
L L L+ N QLR++ + G +L +L L + EL P LF L AL+ + N L
Sbjct: 107 LEQLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNAL 166
Query: 221 QVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLN 42
Q LPD F L NLT + L N+IS + F+G S+ L L NR+A + L
Sbjct: 167 QALPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLG 226
Query: 41 QLHKL 27
+L L
Sbjct: 227 RLMTL 231
Score = 39.9 bits (89), Expect = 0.007
Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Frame = -3
Query: 257 ALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN-R 81
A + + GN + +P + F RNLT + L +N ++ I F G + LDLS N +
Sbjct: 58 ASQRIFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQ 117
Query: 80 LAFAPDSLYSPLNQLHKL 27
L + + L +LH L
Sbjct: 118 LRSVDPATFHGLGRLHTL 135
>AB209005-1|BAD92242.1| 622|Homo sapiens leucine rich repeat and
fibronectin type III domain containing 4 variant
protein.
Length = 622
Score = 68.9 bits (161), Expect = 1e-11
Identities = 53/164 (32%), Positives = 79/164 (48%), Gaps = 3/164 (1%)
Frame = -3
Query: 533 EIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRAL 357
E+++++N L F N+ L L L ++I + F LR+L L N+L L
Sbjct: 39 ELRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVEL 98
Query: 356 PRSVLRGQTQLTSLTLSYNAVAELAPELFAD-LRALETFVMDGNELQVLPDSLFSGLRNL 180
LRG L L LS N + +AP F D L +LE + N L+ +P + + L
Sbjct: 99 GTGSLRGPVNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPAL 158
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLA-FAPDSLYS 51
T++L +N I + F + LDL+ NRLA APD L+S
Sbjct: 159 HTLNLDHNLIDALPPGAFAQLGQLSRLDLTSNRLATLAPDPLFS 202
Score = 64.5 bits (150), Expect = 3e-10
Identities = 43/122 (35%), Positives = 57/122 (46%), Gaps = 1/122 (0%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
L LA N ++AL R T L LTLS NA+ + F DL +L + +DGN L L
Sbjct: 40 LRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELG 99
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQG-ATSIRTLDLSYNRLAFAPDSLYSPLNQLH 33
G NL + L N++ I+ F S+ LDLSYN L P + + LH
Sbjct: 100 TGSLRGPVNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALH 159
Query: 32 KL 27
L
Sbjct: 160 TL 161
>BC050445-1|AAH50445.1| 582|Homo sapiens soc-2 suppressor of clear
homolog (C. elegans) protein.
Length = 582
Score = 68.5 bits (160), Expect = 2e-11
Identities = 53/190 (27%), Positives = 89/190 (46%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ N R + S ++R LD + + + N +T E NL L L + + I++LP E
Sbjct: 176 LRHNKLREIPSVVYR-LDSLTTLYLRFN-RITTVEKDIKNLSKLSMLSIRENKIKQLPAE 233
Query: 416 FISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVM 237
L TL +A NQL LP+ + TQ+T+L L +N + +L P+ +L +L +
Sbjct: 234 IGELCNLITLDVAHNQLEHLPKEI-GNCTQITNLDLQHNELLDL-PDTIGNLSSLSRLGL 291
Query: 236 DGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
N L +P SL + L ++L NN IS + + + +L L+ N P
Sbjct: 292 RYNRLSAIPRSL-AKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGG 350
Query: 56 YSPLNQLHKL 27
S + ++ L
Sbjct: 351 PSQFSTIYSL 360
Score = 56.8 bits (131), Expect = 5e-08
Identities = 50/191 (26%), Positives = 88/191 (46%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE 420
T+ RN F+ I + + +N + +FS L L + + + LP
Sbjct: 337 TLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPL 396
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+F + + + L+LA NQL +P V G L L LS N + +L P +LR L
Sbjct: 397 DFGTWTSMVELNLATNQLTKIPEDV-SGLVSLEVLILSNNLLKKL-PHGLGNLRKLRELD 454
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
++ N+L+ LP+ + + L++L + L NN+++ + T++ L L N L P+
Sbjct: 455 LEENKLESLPNEI-AYLKDLQKLVLTNNQLTTLPRG-IGHLTNLTHLGLGENLLTHLPEE 512
Query: 59 LYSPLNQLHKL 27
+ L L +L
Sbjct: 513 I-GTLENLEEL 522
Score = 53.2 bits (122), Expect = 7e-07
Identities = 47/148 (31%), Positives = 67/148 (45%), Gaps = 1/148 (0%)
Frame = -3
Query: 551 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARN 372
GL ++ + +SNN+ L + NL LR L L+ + + LP E L+ L L N
Sbjct: 423 GLVSLEVLILSNNLLKKLPHGL-GNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNN 481
Query: 371 QLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN-ELQVLPDSLFS 195
QL LPR + T LT L L N + L PE L LE ++ N L LP L +
Sbjct: 482 QLTTLPRGI-GHLTNLTHLGLGENLLTHL-PEEIGTLENLEELYLNDNPNLHSLPFEL-A 538
Query: 194 GLRNLTTVSLRNNKISVISMNTFQGATS 111
L+ +S+ N +S + G S
Sbjct: 539 LCSKLSIMSIENCPLSHLPPQIVAGGPS 566
Score = 38.7 bits (86), Expect = 0.016
Identities = 31/105 (29%), Positives = 51/105 (48%)
Frame = -3
Query: 317 LTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVIS 138
L LS ++ + P +L L + N+LQ LP + L NL T++L N ++ +
Sbjct: 105 LDLSKRSI-HILPSSIKELTQLTELYLYSNKLQSLPAEV-GCLVNLMTLALSENSLTSLP 162
Query: 137 MNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
++ +R LDL +N+L P +Y +L L TL L +N
Sbjct: 163 -DSLDNLKKLRMLDLRHNKLREIPSVVY----RLDSLTTLYLRFN 202
>BC011057-1|AAH11057.2| 620|Homo sapiens leucine rich repeat and Ig
domain containing 1 protein.
Length = 620
Score = 68.5 bits (160), Expect = 2e-11
Identities = 37/123 (30%), Positives = 65/123 (52%)
Frame = -3
Query: 395 RTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 216
R L L +N+++ L + L L L+ N V+ + P F +L L T + N L++
Sbjct: 74 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKL 133
Query: 215 LPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQL 36
+P +F+GL NLT + + NKI ++ FQ ++++L++ N L + +S LN L
Sbjct: 134 IPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSL 193
Query: 35 HKL 27
+L
Sbjct: 194 EQL 196
Score = 66.1 bits (154), Expect = 9e-11
Identities = 41/169 (24%), Positives = 84/169 (49%), Gaps = 1/169 (0%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP-EEF 414
+N + L+ + F H++E++++ N+ ++ F+NL LRTL L + ++ +P F
Sbjct: 80 KNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVF 139
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
S L L ++ N++ L + + L SL + N + ++ F+ L +LE ++
Sbjct: 140 TGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLE 199
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSY 87
L +P S L L + LR+ I+ I +F+ ++ L++S+
Sbjct: 200 KCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISH 248
Score = 64.1 bits (149), Expect = 4e-10
Identities = 45/170 (26%), Positives = 79/170 (46%), Gaps = 1/170 (0%)
Frame = -3
Query: 530 IKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRALP 354
+ + N TL + F++ P L L+L+ + + + P F + LRTL L N+L+ +P
Sbjct: 76 LDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIP 135
Query: 353 RSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTT 174
V G + LT L +S N + L +F DL L++ + N+L + FSGL +L
Sbjct: 136 LGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQ 195
Query: 173 VSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
++L ++ I + L L + + D + L +L L+
Sbjct: 196 LTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLE 245
Score = 57.2 bits (132), Expect = 4e-08
Identities = 33/124 (26%), Positives = 60/124 (48%)
Frame = -3
Query: 395 RTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 216
R + R + A+P + T+ L L N + L + FA LE ++ N +
Sbjct: 53 RAVLCHRKRFVAVPEGI---PTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSA 109
Query: 215 LPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQL 36
+ F+ L NL T+ LR+N++ +I + F G +++ LD+S N++ D ++ L L
Sbjct: 110 VEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNL 169
Query: 35 HKLQ 24
L+
Sbjct: 170 KSLE 173
Score = 53.2 bits (122), Expect = 7e-07
Identities = 30/108 (27%), Positives = 53/108 (49%)
Frame = -3
Query: 398 LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 219
L +LS+ L A+P +R L L LSYN ++ + + +L L+ + G +L
Sbjct: 265 LTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLA 324
Query: 218 VLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLA 75
V+ F GL L +++ N+++ + + F ++ TL L N LA
Sbjct: 325 VVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPLA 372
Score = 52.0 bits (119), Expect = 2e-06
Identities = 45/192 (23%), Positives = 93/192 (48%), Gaps = 4/192 (2%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N + + +F GL ++ ++ IS N + L + +F +L L++L++ + + + S
Sbjct: 129 NRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFS 188
Query: 407 N-SPLRTLSLARNQLRALPR---SVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+ L L+L + L ++P S L G L L+ NA+ + + + L+ LE +
Sbjct: 189 GLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLE--I 246
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
L + + GL NLT++S+ + ++ + + +R L+LSYN ++ S
Sbjct: 247 SHWPYLDTMTPNCLYGL-NLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGS 305
Query: 59 LYSPLNQLHKLQ 24
+ L +L ++Q
Sbjct: 306 MLHELLRLQEIQ 317
>AY899851-1|AAX85199.1| 730|Homo sapiens LGR8.1 protein.
Length = 730
Score = 68.5 bits (160), Expect = 2e-11
Identities = 47/174 (27%), Positives = 78/174 (44%), Gaps = 1/174 (0%)
Frame = -3
Query: 545 DHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQ 369
+++ + + N +L + VF L+ + L + IR + + F L+ L L N
Sbjct: 137 NNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNC 196
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
+ L + + QLT L L N + ++ LF L +L M N L+ LP + + +
Sbjct: 197 ITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQM 256
Query: 188 RNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
L V L N+I ++ +TF S+ LDLS N + L+ L L KL
Sbjct: 257 PQLNWVDLEGNRIKYLTNSTFLSCDSLTVLDLSSNTITELSPHLFKDLKLLQKL 310
Score = 67.3 bits (157), Expect = 4e-11
Identities = 43/156 (27%), Positives = 74/156 (47%), Gaps = 1/156 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N L IF+ L + + + +N + + +F+ L +L L + + + LP++ +
Sbjct: 195 NCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCA 254
Query: 407 NSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
P L + L N+++ L S LT L LS N + EL+P LF DL+ L+ +
Sbjct: 255 QMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLDLSSNTITELSPHLFKDLKLLQKLNLSS 314
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQ 123
N L L + F L+ L ++ L +I I+ FQ
Sbjct: 315 NPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQ 350
>AY324320-1|AAQ97216.1| 620|Homo sapiens leucine-rich repeat
neuronal 6A protein.
Length = 620
Score = 68.5 bits (160), Expect = 2e-11
Identities = 37/123 (30%), Positives = 65/123 (52%)
Frame = -3
Query: 395 RTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 216
R L L +N+++ L + L L L+ N V+ + P F +L L T + N L++
Sbjct: 74 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKL 133
Query: 215 LPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQL 36
+P +F+GL NLT + + NKI ++ FQ ++++L++ N L + +S LN L
Sbjct: 134 IPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSL 193
Query: 35 HKL 27
+L
Sbjct: 194 EQL 196
Score = 66.1 bits (154), Expect = 9e-11
Identities = 41/169 (24%), Positives = 84/169 (49%), Gaps = 1/169 (0%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP-EEF 414
+N + L+ + F H++E++++ N+ ++ F+NL LRTL L + ++ +P F
Sbjct: 80 KNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVF 139
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
S L L ++ N++ L + + L SL + N + ++ F+ L +LE ++
Sbjct: 140 TGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLE 199
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSY 87
L +P S L L + LR+ I+ I +F+ ++ L++S+
Sbjct: 200 KCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISH 248
Score = 64.1 bits (149), Expect = 4e-10
Identities = 45/170 (26%), Positives = 79/170 (46%), Gaps = 1/170 (0%)
Frame = -3
Query: 530 IKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRALP 354
+ + N TL + F++ P L L+L+ + + + P F + LRTL L N+L+ +P
Sbjct: 76 LDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIP 135
Query: 353 RSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTT 174
V G + LT L +S N + L +F DL L++ + N+L + FSGL +L
Sbjct: 136 LGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQ 195
Query: 173 VSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
++L ++ I + L L + + D + L +L L+
Sbjct: 196 LTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLE 245
Score = 57.2 bits (132), Expect = 4e-08
Identities = 33/124 (26%), Positives = 60/124 (48%)
Frame = -3
Query: 395 RTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 216
R + R + A+P + T+ L L N + L + FA LE ++ N +
Sbjct: 53 RAVLCHRKRFVAVPEGI---PTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSA 109
Query: 215 LPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQL 36
+ F+ L NL T+ LR+N++ +I + F G +++ LD+S N++ D ++ L L
Sbjct: 110 VEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNL 169
Query: 35 HKLQ 24
L+
Sbjct: 170 KSLE 173
Score = 53.2 bits (122), Expect = 7e-07
Identities = 30/108 (27%), Positives = 53/108 (49%)
Frame = -3
Query: 398 LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 219
L +LS+ L A+P +R L L LSYN ++ + + +L L+ + G +L
Sbjct: 265 LTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLA 324
Query: 218 VLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLA 75
V+ F GL L +++ N+++ + + F ++ TL L N LA
Sbjct: 325 VVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPLA 372
Score = 52.0 bits (119), Expect = 2e-06
Identities = 45/192 (23%), Positives = 93/192 (48%), Gaps = 4/192 (2%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N + + +F GL ++ ++ IS N + L + +F +L L++L++ + + + S
Sbjct: 129 NRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFS 188
Query: 407 N-SPLRTLSLARNQLRALPR---SVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+ L L+L + L ++P S L G L L+ NA+ + + + L+ LE +
Sbjct: 189 GLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLE--I 246
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
L + + GL NLT++S+ + ++ + + +R L+LSYN ++ S
Sbjct: 247 SHWPYLDTMTPNCLYGL-NLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGS 305
Query: 59 LYSPLNQLHKLQ 24
+ L +L ++Q
Sbjct: 306 MLHELLRLQEIQ 317
>AL834260-1|CAD38935.1| 577|Homo sapiens hypothetical protein
protein.
Length = 577
Score = 68.5 bits (160), Expect = 2e-11
Identities = 37/123 (30%), Positives = 65/123 (52%)
Frame = -3
Query: 395 RTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 216
R L L +N+++ L + L L L+ N V+ + P F +L L T + N L++
Sbjct: 31 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKL 90
Query: 215 LPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQL 36
+P +F+GL NLT + + NKI ++ FQ ++++L++ N L + +S LN L
Sbjct: 91 IPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSL 150
Query: 35 HKL 27
+L
Sbjct: 151 EQL 153
Score = 66.1 bits (154), Expect = 9e-11
Identities = 41/169 (24%), Positives = 84/169 (49%), Gaps = 1/169 (0%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP-EEF 414
+N + L+ + F H++E++++ N+ ++ F+NL LRTL L + ++ +P F
Sbjct: 37 KNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVF 96
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
S L L ++ N++ L + + L SL + N + ++ F+ L +LE ++
Sbjct: 97 TGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLE 156
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSY 87
L +P S L L + LR+ I+ I +F+ ++ L++S+
Sbjct: 157 KCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISH 205
Score = 64.1 bits (149), Expect = 4e-10
Identities = 45/170 (26%), Positives = 79/170 (46%), Gaps = 1/170 (0%)
Frame = -3
Query: 530 IKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRALP 354
+ + N TL + F++ P L L+L+ + + + P F + LRTL L N+L+ +P
Sbjct: 33 LDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIP 92
Query: 353 RSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTT 174
V G + LT L +S N + L +F DL L++ + N+L + FSGL +L
Sbjct: 93 LGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQ 152
Query: 173 VSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
++L ++ I + L L + + D + L +L L+
Sbjct: 153 LTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLE 202
Score = 57.2 bits (132), Expect = 4e-08
Identities = 33/124 (26%), Positives = 60/124 (48%)
Frame = -3
Query: 395 RTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 216
R + R + A+P + T+ L L N + L + FA LE ++ N +
Sbjct: 10 RAVLCHRKRFVAVPEGI---PTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSA 66
Query: 215 LPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQL 36
+ F+ L NL T+ LR+N++ +I + F G +++ LD+S N++ D ++ L L
Sbjct: 67 VEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNL 126
Query: 35 HKLQ 24
L+
Sbjct: 127 KSLE 130
Score = 53.2 bits (122), Expect = 7e-07
Identities = 30/108 (27%), Positives = 53/108 (49%)
Frame = -3
Query: 398 LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 219
L +LS+ L A+P +R L L LSYN ++ + + +L L+ + G +L
Sbjct: 222 LTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLA 281
Query: 218 VLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLA 75
V+ F GL L +++ N+++ + + F ++ TL L N LA
Sbjct: 282 VVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPLA 329
Score = 52.0 bits (119), Expect = 2e-06
Identities = 45/192 (23%), Positives = 93/192 (48%), Gaps = 4/192 (2%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N + + +F GL ++ ++ IS N + L + +F +L L++L++ + + + S
Sbjct: 86 NRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFS 145
Query: 407 N-SPLRTLSLARNQLRALPR---SVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+ L L+L + L ++P S L G L L+ NA+ + + + L+ LE +
Sbjct: 146 GLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLE--I 203
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
L + + GL NLT++S+ + ++ + + +R L+LSYN ++ S
Sbjct: 204 SHWPYLDTMTPNCLYGL-NLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGS 262
Query: 59 LYSPLNQLHKLQ 24
+ L +L ++Q
Sbjct: 263 MLHELLRLQEIQ 274
>AL158163-2|CAH72812.1| 582|Homo sapiens soc-2 suppressor of clear
homolog (C. elegans) protein.
Length = 582
Score = 68.5 bits (160), Expect = 2e-11
Identities = 53/190 (27%), Positives = 89/190 (46%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ N R + S ++R LD + + + N +T E NL L L + + I++LP E
Sbjct: 176 LRHNKLREIPSVVYR-LDSLTTLYLRFN-RITTVEKDIKNLSKLSMLSIRENKIKQLPAE 233
Query: 416 FISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVM 237
L TL +A NQL LP+ + TQ+T+L L +N + +L P+ +L +L +
Sbjct: 234 IGELCNLITLDVAHNQLEHLPKEI-GNCTQITNLDLQHNELLDL-PDTIGNLSSLSRLGL 291
Query: 236 DGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
N L +P SL + L ++L NN IS + + + +L L+ N P
Sbjct: 292 RYNRLSAIPRSL-AKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGG 350
Query: 56 YSPLNQLHKL 27
S + ++ L
Sbjct: 351 PSQFSTIYSL 360
Score = 56.8 bits (131), Expect = 5e-08
Identities = 50/191 (26%), Positives = 88/191 (46%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE 420
T+ RN F+ I + + +N + +FS L L + + + LP
Sbjct: 337 TLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPL 396
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+F + + + L+LA NQL +P V G L L LS N + +L P +LR L
Sbjct: 397 DFGTWTSMVELNLATNQLTKIPEDV-SGLVSLEVLILSNNLLKKL-PHGLGNLRKLRELD 454
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
++ N+L+ LP+ + + L++L + L NN+++ + T++ L L N L P+
Sbjct: 455 LEENKLESLPNEI-AYLKDLQKLVLTNNQLTTLPRG-IGHLTNLTHLGLGENLLTHLPEE 512
Query: 59 LYSPLNQLHKL 27
+ L L +L
Sbjct: 513 I-GTLENLEEL 522
Score = 53.2 bits (122), Expect = 7e-07
Identities = 47/148 (31%), Positives = 67/148 (45%), Gaps = 1/148 (0%)
Frame = -3
Query: 551 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARN 372
GL ++ + +SNN+ L + NL LR L L+ + + LP E L+ L L N
Sbjct: 423 GLVSLEVLILSNNLLKKLPHGL-GNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNN 481
Query: 371 QLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN-ELQVLPDSLFS 195
QL LPR + T LT L L N + L PE L LE ++ N L LP L +
Sbjct: 482 QLTTLPRGI-GHLTNLTHLGLGENLLTHL-PEEIGTLENLEELYLNDNPNLHSLPFEL-A 538
Query: 194 GLRNLTTVSLRNNKISVISMNTFQGATS 111
L+ +S+ N +S + G S
Sbjct: 539 LCSKLSIMSIENCPLSHLPPQIVAGGPS 566
Score = 38.7 bits (86), Expect = 0.016
Identities = 31/105 (29%), Positives = 51/105 (48%)
Frame = -3
Query: 317 LTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVIS 138
L LS ++ + P +L L + N+LQ LP + L NL T++L N ++ +
Sbjct: 105 LDLSKRSI-HILPSSIKELTQLTELYLYSNKLQSLPAEV-GCLVNLMTLALSENSLTSLP 162
Query: 137 MNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
++ +R LDL +N+L P +Y +L L TL L +N
Sbjct: 163 -DSLDNLKKLRMLDLRHNKLREIPSVVY----RLDSLTTLYLRFN 202
>AF068920-1|AAC39856.1| 582|Homo sapiens Ras-binding protein SUR-8
protein.
Length = 582
Score = 68.5 bits (160), Expect = 2e-11
Identities = 53/190 (27%), Positives = 89/190 (46%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ N R + S ++R LD + + + N +T E NL L L + + I++LP E
Sbjct: 176 LRHNKLREIPSVVYR-LDSLTTLYLRFN-RITTVEKDIKNLSKLSMLSIRENKIKQLPAE 233
Query: 416 FISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVM 237
L TL +A NQL LP+ + TQ+T+L L +N + +L P+ +L +L +
Sbjct: 234 IGELCNLITLDVAHNQLEHLPKEI-GNCTQITNLDLQHNELLDL-PDTIGNLSSLSRLGL 291
Query: 236 DGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
N L +P SL + L ++L NN IS + + + +L L+ N P
Sbjct: 292 RYNRLSAIPRSL-AKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGG 350
Query: 56 YSPLNQLHKL 27
S + ++ L
Sbjct: 351 PSQFSTIYSL 360
Score = 56.8 bits (131), Expect = 5e-08
Identities = 50/191 (26%), Positives = 88/191 (46%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE 420
T+ RN F+ I + + +N + +FS L L + + + LP
Sbjct: 337 TLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPL 396
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+F + + + L+LA NQL +P V G L L LS N + +L P +LR L
Sbjct: 397 DFGTWTSMVELNLATNQLTKIPEDV-SGLVSLEVLILSNNLLKKL-PHGLGNLRKLRELD 454
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
++ N+L+ LP+ + + L++L + L NN+++ + T++ L L N L P+
Sbjct: 455 LEENKLESLPNEI-AYLKDLQKLVLTNNQLTTLPRG-IGHLTNLTHLGLGENLLTHLPEE 512
Query: 59 LYSPLNQLHKL 27
+ L L +L
Sbjct: 513 I-GTLENLEEL 522
Score = 53.2 bits (122), Expect = 7e-07
Identities = 47/148 (31%), Positives = 67/148 (45%), Gaps = 1/148 (0%)
Frame = -3
Query: 551 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARN 372
GL ++ + +SNN+ L + NL LR L L+ + + LP E L+ L L N
Sbjct: 423 GLVSLEVLILSNNLLKKLPHGL-GNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNN 481
Query: 371 QLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN-ELQVLPDSLFS 195
QL LPR + T LT L L N + L PE L LE ++ N L LP L +
Sbjct: 482 QLTTLPRGI-GHLTNLTHLGLGENLLTHL-PEEIGTLENLEELYLNDNPNLHSLPFEL-A 538
Query: 194 GLRNLTTVSLRNNKISVISMNTFQGATS 111
L+ +S+ N +S + G S
Sbjct: 539 LCSKLSIMSIENCPLSHLPPQIVAGGPS 566
Score = 38.7 bits (86), Expect = 0.016
Identities = 31/105 (29%), Positives = 51/105 (48%)
Frame = -3
Query: 317 LTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVIS 138
L LS ++ + P +L L + N+LQ LP + L NL T++L N ++ +
Sbjct: 105 LDLSKRSI-HILPSSIKELTQLTELYLYSNKLQSLPAEV-GCLVNLMTLALSENSLTSLP 162
Query: 137 MNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
++ +R LDL +N+L P +Y +L L TL L +N
Sbjct: 163 -DSLDNLKKLRMLDLRHNKLREIPSVVY----RLDSLTTLYLRFN 202
>AF054828-1|AAC25698.1| 582|Homo sapiens leucine-rich repeat
protein SHOC-2 protein.
Length = 582
Score = 68.5 bits (160), Expect = 2e-11
Identities = 53/190 (27%), Positives = 89/190 (46%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ N R + S ++R LD + + + N +T E NL L L + + I++LP E
Sbjct: 176 LRHNKLREIPSVVYR-LDSLTTLYLRFN-RITTVEKDIKNLSKLSMLSIRENKIKQLPAE 233
Query: 416 FISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVM 237
L TL +A NQL LP+ + TQ+T+L L +N + +L P+ +L +L +
Sbjct: 234 IGELCNLITLDVAHNQLEHLPKEI-GNCTQITNLDLQHNELLDL-PDTIGNLSSLSRLGL 291
Query: 236 DGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
N L +P SL + L ++L NN IS + + + +L L+ N P
Sbjct: 292 RYNRLSAIPRSL-AKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGG 350
Query: 56 YSPLNQLHKL 27
S + ++ L
Sbjct: 351 PSQFSTIYSL 360
Score = 56.8 bits (131), Expect = 5e-08
Identities = 50/191 (26%), Positives = 88/191 (46%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE 420
T+ RN F+ I + + +N + +FS L L + + + LP
Sbjct: 337 TLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPL 396
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+F + + + L+LA NQL +P V G L L LS N + +L P +LR L
Sbjct: 397 DFGTWTSMVELNLATNQLTKIPEDV-SGLVSLEVLILSNNLLKKL-PHGLGNLRKLRELD 454
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
++ N+L+ LP+ + + L++L + L NN+++ + T++ L L N L P+
Sbjct: 455 LEENKLESLPNEI-AYLKDLQKLVLTNNQLTTLPRG-IGHLTNLTHLGLGENLLTHLPEE 512
Query: 59 LYSPLNQLHKL 27
+ L L +L
Sbjct: 513 I-GTLENLEEL 522
Score = 53.2 bits (122), Expect = 7e-07
Identities = 47/148 (31%), Positives = 67/148 (45%), Gaps = 1/148 (0%)
Frame = -3
Query: 551 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARN 372
GL ++ + +SNN+ L + NL LR L L+ + + LP E L+ L L N
Sbjct: 423 GLVSLEVLILSNNLLKKLPHGL-GNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNN 481
Query: 371 QLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN-ELQVLPDSLFS 195
QL LPR + T LT L L N + L PE L LE ++ N L LP L +
Sbjct: 482 QLTTLPRGI-GHLTNLTHLGLGENLLTHL-PEEIGTLENLEELYLNDNPNLHSLPFEL-A 538
Query: 194 GLRNLTTVSLRNNKISVISMNTFQGATS 111
L+ +S+ N +S + G S
Sbjct: 539 LCSKLSIMSIENCPLSHLPPQIVAGGPS 566
Score = 38.7 bits (86), Expect = 0.016
Identities = 31/105 (29%), Positives = 51/105 (48%)
Frame = -3
Query: 317 LTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVIS 138
L LS ++ + P +L L + N+LQ LP + L NL T++L N ++ +
Sbjct: 105 LDLSKRSI-HILPSSIKELTQLTELYLYSNKLQSLPAEV-GCLVNLMTLALSENSLTSLP 162
Query: 137 MNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
++ +R LDL +N+L P +Y +L L TL L +N
Sbjct: 163 -DSLDNLKKLRMLDLRHNKLREIPSVVY----RLDSLTTLYLRFN 202
>AB020669-1|BAA74885.2| 584|Homo sapiens KIAA0862 protein protein.
Length = 584
Score = 68.5 bits (160), Expect = 2e-11
Identities = 53/190 (27%), Positives = 89/190 (46%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ N R + S ++R LD + + + N +T E NL L L + + I++LP E
Sbjct: 178 LRHNKLREIPSVVYR-LDSLTTLYLRFN-RITTVEKDIKNLSKLSMLSIRENKIKQLPAE 235
Query: 416 FISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVM 237
L TL +A NQL LP+ + TQ+T+L L +N + +L P+ +L +L +
Sbjct: 236 IGELCNLITLDVAHNQLEHLPKEI-GNCTQITNLDLQHNELLDL-PDTIGNLSSLSRLGL 293
Query: 236 DGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
N L +P SL + L ++L NN IS + + + +L L+ N P
Sbjct: 294 RYNRLSAIPRSL-AKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGG 352
Query: 56 YSPLNQLHKL 27
S + ++ L
Sbjct: 353 PSQFSTIYSL 362
Score = 56.8 bits (131), Expect = 5e-08
Identities = 50/191 (26%), Positives = 88/191 (46%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE 420
T+ RN F+ I + + +N + +FS L L + + + LP
Sbjct: 339 TLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPL 398
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+F + + + L+LA NQL +P V G L L LS N + +L P +LR L
Sbjct: 399 DFGTWTSMVELNLATNQLTKIPEDV-SGLVSLEVLILSNNLLKKL-PHGLGNLRKLRELD 456
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
++ N+L+ LP+ + + L++L + L NN+++ + T++ L L N L P+
Sbjct: 457 LEENKLESLPNEI-AYLKDLQKLVLTNNQLTTLPRG-IGHLTNLTHLGLGENLLTHLPEE 514
Query: 59 LYSPLNQLHKL 27
+ L L +L
Sbjct: 515 I-GTLENLEEL 524
Score = 52.8 bits (121), Expect = 9e-07
Identities = 47/148 (31%), Positives = 67/148 (45%), Gaps = 1/148 (0%)
Frame = -3
Query: 551 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARN 372
GL ++ + +SNN+ L + NL LR L L+ + + LP E L+ L L N
Sbjct: 425 GLVSLEVLILSNNLLKKLPHGL-GNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNN 483
Query: 371 QLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN-ELQVLPDSLFS 195
QL LPR + T LT L L N + L PE L LE ++ N L LP L +
Sbjct: 484 QLTTLPRGI-GHLTNLTHLGLGENLLTHL-PEEIGTLENLEELYLNDNPNLHSLPLEL-A 540
Query: 194 GLRNLTTVSLRNNKISVISMNTFQGATS 111
L+ +S+ N +S + G S
Sbjct: 541 LCSKLSIMSIENCPLSHLPPQIVAGGPS 568
Score = 38.7 bits (86), Expect = 0.016
Identities = 31/105 (29%), Positives = 51/105 (48%)
Frame = -3
Query: 317 LTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVIS 138
L LS ++ + P +L L + N+LQ LP + L NL T++L N ++ +
Sbjct: 107 LDLSKRSI-HILPSSIKELTQLTELYLYSNKLQSLPAEV-GCLVNLMTLALSENSLTSLP 164
Query: 137 MNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
++ +R LDL +N+L P +Y +L L TL L +N
Sbjct: 165 -DSLDNLKKLRMLDLRHNKLREIPSVVY----RLDSLTTLYLRFN 204
>BC115015-1|AAI15016.1| 1367|Homo sapiens ERBB2IP protein protein.
Length = 1367
Score = 68.1 bits (159), Expect = 2e-11
Identities = 61/199 (30%), Positives = 90/199 (45%)
Frame = -3
Query: 602 FTMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP 423
F M N ++ I L + + +S N ++E + S L+ L L +S+++LP
Sbjct: 212 FWMDANRLTFIPGFI-GSLKQLTYLDVSKNNIEMVEEGI-STCENLQDLLLSSNSLQQLP 269
Query: 422 EEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETF 243
E S + TL + NQL LP S+ G + L S+N V E P L L TF
Sbjct: 270 ETIGSLKNITTLKIDENQLMYLPDSI-GGLISVEELDCSFNEV-EALPSSIGQLTNLRTF 327
Query: 242 VMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPD 63
D N LQ LP + S +N+T + L +NK+ + ++ ++LS NRL P
Sbjct: 328 AADHNYLQQLPPEIGS-WKNITVLFLHSNKLETLP-EEMGDMQKLKVINLSDNRLKNLPF 385
Query: 62 SLYSPLNQLHKLQTLTLAW 6
S KLQ LT W
Sbjct: 386 S-------FTKLQQLTAMW 397
Score = 64.9 bits (151), Expect = 2e-10
Identities = 51/162 (31%), Positives = 76/162 (46%)
Frame = -3
Query: 488 VFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTL 309
+F+ L L LD + I ELP++ + L LSL N L LP S+ L L +
Sbjct: 41 IFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASI-ANLINLRELDV 99
Query: 308 SYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNT 129
S N + E PE + + L N + LPD FS L NLT + L + + + N
Sbjct: 100 SKNGIQEF-PENIKNCKVLTIVEASVNPISKLPDG-FSQLLNLTQLYLNDAFLEFLPAN- 156
Query: 128 FQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
F T ++ L+L N+L P + +N+L +L+ L L N
Sbjct: 157 FDRLTKLQILELRENQLKMLPKT----MNRLTQLERLDLGSN 194
Score = 63.3 bits (147), Expect = 6e-10
Identities = 48/148 (32%), Positives = 72/148 (48%)
Frame = -3
Query: 485 FSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLS 306
FS L L L L+ + + LP F + L+ L L NQL+ LP+++ R TQL L L
Sbjct: 134 FSQLLNLTQLYLNDAFLEFLPANFDRLTKLQILELRENQLKMLPKTMNR-LTQLERLDLG 192
Query: 305 YNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTF 126
N E+ PE+ L L+ F MD N L +P L+ LT + + N I ++
Sbjct: 193 SNEFTEV-PEVLEQLSGLKEFWMDANRLTFIP-GFIGSLKQLTYLDVSKNNIEMVE-EGI 249
Query: 125 QGATSIRTLDLSYNRLAFAPDSLYSPLN 42
+++ L LS N L P+++ S N
Sbjct: 250 STCENLQDLLLSSNSLQQLPETIGSLKN 277
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/105 (26%), Positives = 61/105 (58%), Gaps = 1/105 (0%)
Frame = -3
Query: 368 LRALPRSVLRGQTQ-LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSG 192
+R +P LRG+ + +T+L S+ ++ ++ E+F + LE +D N+++ LP LF+
Sbjct: 9 VRLVPCRCLRGEEETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFN- 67
Query: 191 LRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
++L +SL +N ++ + + ++R LD+S N + P+++
Sbjct: 68 CQSLHKLSLPDNDLTTLPA-SIANLINLRELDVSKNGIQEFPENI 111
>BC115012-1|AAI15013.1| 1371|Homo sapiens erbb2 interacting protein
protein.
Length = 1371
Score = 68.1 bits (159), Expect = 2e-11
Identities = 61/199 (30%), Positives = 90/199 (45%)
Frame = -3
Query: 602 FTMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP 423
F M N ++ I L + + +S N ++E + S L+ L L +S+++LP
Sbjct: 212 FWMDANRLTFIPGFI-GSLKQLTYLDVSKNNIEMVEEGI-STCENLQDLLLSSNSLQQLP 269
Query: 422 EEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETF 243
E S + TL + NQL LP S+ G + L S+N V E P L L TF
Sbjct: 270 EPIGSLKNITTLKIDENQLMYLPDSI-GGLISVEELDCSFNEV-EALPSSIGQLTNLRTF 327
Query: 242 VMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPD 63
D N LQ LP + S +N+T + L +NK+ + ++ ++LS NRL P
Sbjct: 328 AADHNYLQQLPPEIGS-WKNITVLFLHSNKLETLP-EEMGDMQKLKVINLSDNRLKNLPF 385
Query: 62 SLYSPLNQLHKLQTLTLAW 6
S KLQ LT W
Sbjct: 386 S-------FTKLQQLTAMW 397
Score = 64.1 bits (149), Expect = 4e-10
Identities = 51/162 (31%), Positives = 76/162 (46%)
Frame = -3
Query: 488 VFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTL 309
+F+ L L LD + I ELP++ + L LSL N L LP S+ L L +
Sbjct: 41 IFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASI-ANLINLRELDV 99
Query: 308 SYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNT 129
S N + E PE + + L N + LPD FS L NLT + L + + + N
Sbjct: 100 SKNGIQEF-PENIKNCKVLTIVEASVNPISKLPDG-FSQLLNLTQLYLNDAFLEFLPAN- 156
Query: 128 FQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
F T ++ L+L N+L P + +N+L +L+ L L N
Sbjct: 157 FGRLTKLQILELRENQLKMLPKT----MNRLTQLERLDLGSN 194
Score = 63.7 bits (148), Expect = 5e-10
Identities = 51/161 (31%), Positives = 76/161 (47%)
Frame = -3
Query: 485 FSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLS 306
FS L L L L+ + + LP F + L+ L L NQL+ LP+++ R TQL L L
Sbjct: 134 FSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNR-LTQLERLDLG 192
Query: 305 YNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTF 126
N E+ PE+ L L+ F MD N L +P L+ LT + + N I ++
Sbjct: 193 SNEFTEV-PEVLEQLSGLKEFWMDANRLTFIP-GFIGSLKQLTYLDVSKNNIEMVE-EGI 249
Query: 125 QGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
+++ L LS N L P+ P+ L + TL + N
Sbjct: 250 STCENLQDLLLSSNSLQQLPE----PIGSLKNITTLKIDEN 286
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/105 (26%), Positives = 61/105 (58%), Gaps = 1/105 (0%)
Frame = -3
Query: 368 LRALPRSVLRGQTQ-LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSG 192
+R +P LRG+ + +T+L S+ ++ ++ E+F + LE +D N+++ LP LF+
Sbjct: 9 VRLVPCRCLRGEEETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFN- 67
Query: 191 LRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
++L +SL +N ++ + + ++R LD+S N + P+++
Sbjct: 68 CQSLHKLSLPDNDLTTLPA-SIANLINLRELDVSKNGIQEFPENI 111
>BC071561-1|AAH71561.1| 1070|Homo sapiens LRIG1 protein protein.
Length = 1070
Score = 68.1 bits (159), Expect = 2e-11
Identities = 51/196 (26%), Positives = 91/196 (46%), Gaps = 1/196 (0%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE- 420
+ +N L F+ L + ++ ++ N ++ F L +L L+L ++I +L +
Sbjct: 195 LSKNRITQLPVRAFK-LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDG 253
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
F S + L L N L + L G T L L LS N++A + + ++ + L V
Sbjct: 254 AFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELV 313
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
+ N L L + + L +L+ + L +N IS I+ F+G S+R LDL +N ++ +
Sbjct: 314 LSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIED 373
Query: 59 LYSPLNQLHKLQTLTL 12
+ L L L L
Sbjct: 374 TSGAFSGLDSLSKLLL 389
Score = 62.9 bits (146), Expect = 8e-10
Identities = 45/172 (26%), Positives = 83/172 (48%), Gaps = 1/172 (0%)
Frame = -3
Query: 536 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRAL 357
+ + +S N + A F +LP L+ + L+ + + +P ++S + +L L N++R++
Sbjct: 71 RSLNLSYNKFSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGAASSHVVSLFLQHNKIRSV 130
Query: 356 PRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL-RNL 180
S L+ L L LS N + E+ F ++ + GN + L F GL R+L
Sbjct: 131 EGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSL 190
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
T+ L N+I+ + + F+ + LDL+ NR+ + LN L L+
Sbjct: 191 LTLRLSKNRITQLPVRAFK-LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLK 241
Score = 60.9 bits (141), Expect = 3e-09
Identities = 51/189 (26%), Positives = 86/189 (45%), Gaps = 2/189 (1%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP-EEFI 411
N F +D F L ++QE+ ++NN LT ++ + + +L L + IR + +
Sbjct: 78 NKFSEIDPAGFEDLPNLQEVYLNNN-ELTAVPSLGAASSHVVSLFLQHNKIRSVEGSQLK 136
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADL-RALETFVMD 234
+ L L L+ N + + + + L L+ N + L F L R+L T +
Sbjct: 137 AYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLS 196
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
N + LP F L LT + L N+I +I TFQG S+ L L N ++ D +
Sbjct: 197 KNRITQLPVRAFK-LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAF 255
Query: 53 SPLNQLHKL 27
L+++H L
Sbjct: 256 WGLSKMHVL 264
Score = 58.4 bits (135), Expect = 2e-08
Identities = 46/173 (26%), Positives = 75/173 (43%), Gaps = 1/173 (0%)
Frame = -3
Query: 539 IQEIKISNNVPLTLKEAVFSNLP-ALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLR 363
I+E+ ++ N TL+ F L +L TL+L + I +LP L L L RN++R
Sbjct: 165 IKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAFKLPRLTQLDLNRNRIR 224
Query: 362 ALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRN 183
+ +G L L L N +++L F L + ++ N L + GL
Sbjct: 225 LIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTA 284
Query: 182 LTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
L + L NN I+ I + + L LS+N L + + L+ L L+
Sbjct: 285 LHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLR 337
Score = 44.4 bits (100), Expect = 3e-04
Identities = 52/218 (23%), Positives = 87/218 (39%), Gaps = 28/218 (12%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ RN+ L F GL + + + N + + L AL L L +SI + +
Sbjct: 242 LQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRK 301
Query: 416 FISN-SPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
S L L L+ N L L L + L+ L LS+N+++ +A F LR+L
Sbjct: 302 GWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLD 361
Query: 239 MDGNELQ-VLPDS--LFSGLRNLTTV------------------------SLRNNKISVI 141
+D NE+ + D+ FSGL +L+ + +L NKI +
Sbjct: 362 LDHNEISGTIEDTSGAFSGLDSLSKLLLLEPSQSAGCSSPSQPHMSAGGRTLFGNKIKSV 421
Query: 140 SMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+ F G + L+L N + + + L +L
Sbjct: 422 AKRAFSGLEGLEHLNLGGNAIRSVQFDAFVKMKNLKEL 459
Score = 35.5 bits (78), Expect = 0.14
Identities = 40/166 (24%), Positives = 70/166 (42%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N+ LD E L + +++S+N + E F L +LR L LD + I
Sbjct: 317 NNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEI--------- 367
Query: 407 NSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 228
+ + S A + L +L + +L +Q S + P + A R L GN
Sbjct: 368 SGTIEDTSGAFSGLDSLSKLLLLEPSQ------SAGCSSPSQPHMSAGGRTLF-----GN 416
Query: 227 ELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLS 90
+++ + FSGL L ++L N I + + F +++ L +S
Sbjct: 417 KIKSVAKRAFSGLEGLEHLNLGGNAIRSVQFDAFVKMKNLKELHIS 462
>BC050692-1|AAH50692.1| 633|Homo sapiens ERBB2IP protein protein.
Length = 633
Score = 68.1 bits (159), Expect = 2e-11
Identities = 61/199 (30%), Positives = 90/199 (45%)
Frame = -3
Query: 602 FTMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP 423
F M N ++ I L + + +S N ++E + S L+ L L +S+++LP
Sbjct: 212 FWMDANRLTFIPGFI-GSLKQLTYLDVSKNNIEMVEEGI-STCENLQDLLLSSNSLQQLP 269
Query: 422 EEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETF 243
E S + TL + NQL LP S+ G + L S+N V E P L L TF
Sbjct: 270 ETIGSLKNITTLKIDENQLMYLPDSI-GGLISVEELDCSFNEV-EALPSSIGQLTNLRTF 327
Query: 242 VMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPD 63
D N LQ LP + S +N+T + L +NK+ + ++ ++LS NRL P
Sbjct: 328 AADHNYLQQLPPEIGS-WKNITVLFLHSNKLETLP-EEMGDMQKLKVINLSDNRLKNLPF 385
Query: 62 SLYSPLNQLHKLQTLTLAW 6
S KLQ LT W
Sbjct: 386 S-------FTKLQQLTAMW 397
Score = 64.1 bits (149), Expect = 4e-10
Identities = 51/162 (31%), Positives = 76/162 (46%)
Frame = -3
Query: 488 VFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTL 309
+F+ L L LD + I ELP++ + L LSL N L LP S+ L L +
Sbjct: 41 IFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASI-ANLINLRELDV 99
Query: 308 SYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNT 129
S N + E PE + + L N + LPD FS L NLT + L + + + N
Sbjct: 100 SKNGIQEF-PENIKNCKVLTIVEASVNPISKLPDG-FSQLLNLTQLYLNDAFLEFLPAN- 156
Query: 128 FQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
F T ++ L+L N+L P + +N+L +L+ L L N
Sbjct: 157 FGRLTKLQILELRENQLKMLPKT----MNRLTQLERLDLGSN 194
Score = 62.9 bits (146), Expect = 8e-10
Identities = 48/148 (32%), Positives = 72/148 (48%)
Frame = -3
Query: 485 FSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLS 306
FS L L L L+ + + LP F + L+ L L NQL+ LP+++ R TQL L L
Sbjct: 134 FSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNR-LTQLERLDLG 192
Query: 305 YNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTF 126
N E+ PE+ L L+ F MD N L +P L+ LT + + N I ++
Sbjct: 193 SNEFTEV-PEVLEQLSGLKEFWMDANRLTFIP-GFIGSLKQLTYLDVSKNNIEMVE-EGI 249
Query: 125 QGATSIRTLDLSYNRLAFAPDSLYSPLN 42
+++ L LS N L P+++ S N
Sbjct: 250 STCENLQDLLLSSNSLQQLPETIGSLKN 277
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/105 (26%), Positives = 61/105 (58%), Gaps = 1/105 (0%)
Frame = -3
Query: 368 LRALPRSVLRGQTQ-LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSG 192
+R +P LRG+ + +T+L S+ ++ ++ E+F + LE +D N+++ LP LF+
Sbjct: 9 VRLVPCRCLRGEEETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFN- 67
Query: 191 LRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
++L +SL +N ++ + + ++R LD+S N + P+++
Sbjct: 68 CQSLHKLSLPDNDLTTLPA-SIANLINLRELDVSKNGIQEFPENI 111
>AL391728-2|CAH73692.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 68.1 bits (159), Expect = 2e-11
Identities = 55/156 (35%), Positives = 76/156 (48%)
Frame = -3
Query: 485 FSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLS 306
F+ L L L L+ + + LP F LR L L N L+ LP+S+ + QL L L
Sbjct: 139 FTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHK-LAQLERLDLG 197
Query: 305 YNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTF 126
N EL PE+ ++ L MD N LQVLP S+ L+ L + + N+I + M+
Sbjct: 198 NNEFGEL-PEVLDQIQNLRELWMDNNALQVLPGSI-GKLKMLVYLDMSKNRIETVDMD-I 254
Query: 125 QGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTL 18
G ++ L LS N L PDS + L KL TL
Sbjct: 255 SGCEALEDLLLSSNMLQQLPDS----IGLLKKLTTL 286
Score = 58.4 bits (135), Expect = 2e-08
Identities = 49/152 (32%), Positives = 73/152 (48%)
Frame = -3
Query: 482 SNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSY 303
S AL L L + +++LP+ L TL + NQL LP ++ + L S
Sbjct: 255 SGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTI-GNLSLLEEFDCSC 313
Query: 302 NAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQ 123
N + L P L +L T +D N L LP + S +N+T +SLR+NK+ + Q
Sbjct: 314 NELESL-PSTIGYLHSLRTLAVDENFLPELPREIGS-CKNVTVMSLRSNKLEFLPEEIGQ 371
Query: 122 GATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+R L+LS NRL P S ++ L +L L
Sbjct: 372 -MQKLRVLNLSDNRLKNLPFS-FTKLKELAAL 401
Score = 45.2 bits (102), Expect = 2e-04
Identities = 28/104 (26%), Positives = 57/104 (54%), Gaps = 1/104 (0%)
Frame = -3
Query: 365 RALPRSVLRGQTQLTS-LTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
R +P RG+ ++ S L S+ ++ ++ E+F R LE +D N+++ LP LF+
Sbjct: 15 RLVPCRCFRGEEEIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFN-C 73
Query: 188 RNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
+ L +S+ +N +S + T +++ LD+S N + P+++
Sbjct: 74 QALRKLSIPDNDLSNLP-TTIASLVNLKELDISKNGVQEFPENI 116
Score = 44.8 bits (101), Expect = 2e-04
Identities = 36/132 (27%), Positives = 59/132 (44%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L + +K+ +N LT+ NL L + + LP LRTL++ N
Sbjct: 280 LKKLTTLKVDDN-QLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENF 338
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
L LPR + +T ++L N + E PE ++ L + N L+ LP S F+ L
Sbjct: 339 LPELPREI-GSCKNVTVMSLRSNKL-EFLPEEIGQMQKLRVLNLSDNRLKNLPFS-FTKL 395
Query: 188 RNLTTVSLRNNK 153
+ L + L +N+
Sbjct: 396 KELAALWLSDNQ 407
Score = 41.9 bits (94), Expect = 0.002
Identities = 37/113 (32%), Positives = 54/113 (47%), Gaps = 1/113 (0%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L ++E S N +L + L +LRTL +D + + ELP E S + +SL N+
Sbjct: 303 LSLLEEFDCSCNELESLPSTI-GYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNK 361
Query: 368 LRALPRSVLRGQTQ-LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVL 213
L LP + GQ Q L L LS N + L P F L+ L + N+ + L
Sbjct: 362 LEFLPEEI--GQMQKLRVLNLSDNRLKNL-PFSFTKLKELAALWLSDNQSKAL 411
>AL391728-1|CAH73691.1| 1537|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1537
Score = 68.1 bits (159), Expect = 2e-11
Identities = 55/156 (35%), Positives = 76/156 (48%)
Frame = -3
Query: 485 FSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLS 306
F+ L L L L+ + + LP F LR L L N L+ LP+S+ + QL L L
Sbjct: 134 FTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHK-LAQLERLDLG 192
Query: 305 YNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTF 126
N EL PE+ ++ L MD N LQVLP S+ L+ L + + N+I + M+
Sbjct: 193 NNEFGEL-PEVLDQIQNLRELWMDNNALQVLPGSI-GKLKMLVYLDMSKNRIETVDMD-I 249
Query: 125 QGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTL 18
G ++ L LS N L PDS + L KL TL
Sbjct: 250 SGCEALEDLLLSSNMLQQLPDS----IGLLKKLTTL 281
Score = 58.4 bits (135), Expect = 2e-08
Identities = 49/152 (32%), Positives = 73/152 (48%)
Frame = -3
Query: 482 SNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSY 303
S AL L L + +++LP+ L TL + NQL LP ++ + L S
Sbjct: 250 SGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTI-GNLSLLEEFDCSC 308
Query: 302 NAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQ 123
N + L P L +L T +D N L LP + S +N+T +SLR+NK+ + Q
Sbjct: 309 NELESL-PSTIGYLHSLRTLAVDENFLPELPREIGS-CKNVTVMSLRSNKLEFLPEEIGQ 366
Query: 122 GATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+R L+LS NRL P S ++ L +L L
Sbjct: 367 -MQKLRVLNLSDNRLKNLPFS-FTKLKELAAL 396
Score = 45.2 bits (102), Expect = 2e-04
Identities = 28/104 (26%), Positives = 57/104 (54%), Gaps = 1/104 (0%)
Frame = -3
Query: 365 RALPRSVLRGQTQLTS-LTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
R +P RG+ ++ S L S+ ++ ++ E+F R LE +D N+++ LP LF+
Sbjct: 10 RLVPCRCFRGEEEIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFN-C 68
Query: 188 RNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
+ L +S+ +N +S + T +++ LD+S N + P+++
Sbjct: 69 QALRKLSIPDNDLSNLP-TTIASLVNLKELDISKNGVQEFPENI 111
Score = 44.8 bits (101), Expect = 2e-04
Identities = 36/132 (27%), Positives = 59/132 (44%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L + +K+ +N LT+ NL L + + LP LRTL++ N
Sbjct: 275 LKKLTTLKVDDN-QLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENF 333
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
L LPR + +T ++L N + E PE ++ L + N L+ LP S F+ L
Sbjct: 334 LPELPREI-GSCKNVTVMSLRSNKL-EFLPEEIGQMQKLRVLNLSDNRLKNLPFS-FTKL 390
Query: 188 RNLTTVSLRNNK 153
+ L + L +N+
Sbjct: 391 KELAALWLSDNQ 402
Score = 41.9 bits (94), Expect = 0.002
Identities = 37/113 (32%), Positives = 54/113 (47%), Gaps = 1/113 (0%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L ++E S N +L + L +LRTL +D + + ELP E S + +SL N+
Sbjct: 298 LSLLEEFDCSCNELESLPSTI-GYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNK 356
Query: 368 LRALPRSVLRGQTQ-LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVL 213
L LP + GQ Q L L LS N + L P F L+ L + N+ + L
Sbjct: 357 LEFLPEEI--GQMQKLRVLNLSDNRLKNL-PFSFTKLKELAALWLSDNQSKAL 406
>AL359412-2|CAH74019.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 68.1 bits (159), Expect = 2e-11
Identities = 55/156 (35%), Positives = 76/156 (48%)
Frame = -3
Query: 485 FSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLS 306
F+ L L L L+ + + LP F LR L L N L+ LP+S+ + QL L L
Sbjct: 139 FTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHK-LAQLERLDLG 197
Query: 305 YNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTF 126
N EL PE+ ++ L MD N LQVLP S+ L+ L + + N+I + M+
Sbjct: 198 NNEFGEL-PEVLDQIQNLRELWMDNNALQVLPGSI-GKLKMLVYLDMSKNRIETVDMD-I 254
Query: 125 QGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTL 18
G ++ L LS N L PDS + L KL TL
Sbjct: 255 SGCEALEDLLLSSNMLQQLPDS----IGLLKKLTTL 286
Score = 58.4 bits (135), Expect = 2e-08
Identities = 49/152 (32%), Positives = 73/152 (48%)
Frame = -3
Query: 482 SNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSY 303
S AL L L + +++LP+ L TL + NQL LP ++ + L S
Sbjct: 255 SGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTI-GNLSLLEEFDCSC 313
Query: 302 NAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQ 123
N + L P L +L T +D N L LP + S +N+T +SLR+NK+ + Q
Sbjct: 314 NELESL-PSTIGYLHSLRTLAVDENFLPELPREIGS-CKNVTVMSLRSNKLEFLPEEIGQ 371
Query: 122 GATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+R L+LS NRL P S ++ L +L L
Sbjct: 372 -MQKLRVLNLSDNRLKNLPFS-FTKLKELAAL 401
Score = 45.2 bits (102), Expect = 2e-04
Identities = 28/104 (26%), Positives = 57/104 (54%), Gaps = 1/104 (0%)
Frame = -3
Query: 365 RALPRSVLRGQTQLTS-LTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
R +P RG+ ++ S L S+ ++ ++ E+F R LE +D N+++ LP LF+
Sbjct: 15 RLVPCRCFRGEEEIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFN-C 73
Query: 188 RNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
+ L +S+ +N +S + T +++ LD+S N + P+++
Sbjct: 74 QALRKLSIPDNDLSNLP-TTIASLVNLKELDISKNGVQEFPENI 116
Score = 44.8 bits (101), Expect = 2e-04
Identities = 36/132 (27%), Positives = 59/132 (44%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L + +K+ +N LT+ NL L + + LP LRTL++ N
Sbjct: 280 LKKLTTLKVDDN-QLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENF 338
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
L LPR + +T ++L N + E PE ++ L + N L+ LP S F+ L
Sbjct: 339 LPELPREI-GSCKNVTVMSLRSNKL-EFLPEEIGQMQKLRVLNLSDNRLKNLPFS-FTKL 395
Query: 188 RNLTTVSLRNNK 153
+ L + L +N+
Sbjct: 396 KELAALWLSDNQ 407
Score = 41.9 bits (94), Expect = 0.002
Identities = 37/113 (32%), Positives = 54/113 (47%), Gaps = 1/113 (0%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L ++E S N +L + L +LRTL +D + + ELP E S + +SL N+
Sbjct: 303 LSLLEEFDCSCNELESLPSTI-GYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNK 361
Query: 368 LRALPRSVLRGQTQ-LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVL 213
L LP + GQ Q L L LS N + L P F L+ L + N+ + L
Sbjct: 362 LEFLPEEI--GQMQKLRVLNLSDNRLKNL-PFSFTKLKELAALWLSDNQSKAL 411
>AL359412-1|CAH74018.1| 1537|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1537
Score = 68.1 bits (159), Expect = 2e-11
Identities = 55/156 (35%), Positives = 76/156 (48%)
Frame = -3
Query: 485 FSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLS 306
F+ L L L L+ + + LP F LR L L N L+ LP+S+ + QL L L
Sbjct: 134 FTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHK-LAQLERLDLG 192
Query: 305 YNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTF 126
N EL PE+ ++ L MD N LQVLP S+ L+ L + + N+I + M+
Sbjct: 193 NNEFGEL-PEVLDQIQNLRELWMDNNALQVLPGSI-GKLKMLVYLDMSKNRIETVDMD-I 249
Query: 125 QGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTL 18
G ++ L LS N L PDS + L KL TL
Sbjct: 250 SGCEALEDLLLSSNMLQQLPDS----IGLLKKLTTL 281
Score = 58.4 bits (135), Expect = 2e-08
Identities = 49/152 (32%), Positives = 73/152 (48%)
Frame = -3
Query: 482 SNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSY 303
S AL L L + +++LP+ L TL + NQL LP ++ + L S
Sbjct: 250 SGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTI-GNLSLLEEFDCSC 308
Query: 302 NAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQ 123
N + L P L +L T +D N L LP + S +N+T +SLR+NK+ + Q
Sbjct: 309 NELESL-PSTIGYLHSLRTLAVDENFLPELPREIGS-CKNVTVMSLRSNKLEFLPEEIGQ 366
Query: 122 GATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+R L+LS NRL P S ++ L +L L
Sbjct: 367 -MQKLRVLNLSDNRLKNLPFS-FTKLKELAAL 396
Score = 45.2 bits (102), Expect = 2e-04
Identities = 28/104 (26%), Positives = 57/104 (54%), Gaps = 1/104 (0%)
Frame = -3
Query: 365 RALPRSVLRGQTQLTS-LTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
R +P RG+ ++ S L S+ ++ ++ E+F R LE +D N+++ LP LF+
Sbjct: 10 RLVPCRCFRGEEEIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFN-C 68
Query: 188 RNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
+ L +S+ +N +S + T +++ LD+S N + P+++
Sbjct: 69 QALRKLSIPDNDLSNLP-TTIASLVNLKELDISKNGVQEFPENI 111
Score = 44.8 bits (101), Expect = 2e-04
Identities = 36/132 (27%), Positives = 59/132 (44%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L + +K+ +N LT+ NL L + + LP LRTL++ N
Sbjct: 275 LKKLTTLKVDDN-QLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENF 333
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
L LPR + +T ++L N + E PE ++ L + N L+ LP S F+ L
Sbjct: 334 LPELPREI-GSCKNVTVMSLRSNKL-EFLPEEIGQMQKLRVLNLSDNRLKNLPFS-FTKL 390
Query: 188 RNLTTVSLRNNK 153
+ L + L +N+
Sbjct: 391 KELAALWLSDNQ 402
Score = 41.9 bits (94), Expect = 0.002
Identities = 37/113 (32%), Positives = 54/113 (47%), Gaps = 1/113 (0%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L ++E S N +L + L +LRTL +D + + ELP E S + +SL N+
Sbjct: 298 LSLLEEFDCSCNELESLPSTI-GYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNK 356
Query: 368 LRALPRSVLRGQTQ-LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVL 213
L LP + GQ Q L L LS N + L P F L+ L + N+ + L
Sbjct: 357 LEFLPEEI--GQMQKLRVLNLSDNRLKNL-PFSFTKLKELAALWLSDNQSKAL 406
>AL158840-2|CAH70975.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 68.1 bits (159), Expect = 2e-11
Identities = 55/156 (35%), Positives = 76/156 (48%)
Frame = -3
Query: 485 FSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLS 306
F+ L L L L+ + + LP F LR L L N L+ LP+S+ + QL L L
Sbjct: 139 FTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHK-LAQLERLDLG 197
Query: 305 YNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTF 126
N EL PE+ ++ L MD N LQVLP S+ L+ L + + N+I + M+
Sbjct: 198 NNEFGEL-PEVLDQIQNLRELWMDNNALQVLPGSI-GKLKMLVYLDMSKNRIETVDMD-I 254
Query: 125 QGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTL 18
G ++ L LS N L PDS + L KL TL
Sbjct: 255 SGCEALEDLLLSSNMLQQLPDS----IGLLKKLTTL 286
Score = 58.4 bits (135), Expect = 2e-08
Identities = 49/152 (32%), Positives = 73/152 (48%)
Frame = -3
Query: 482 SNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSY 303
S AL L L + +++LP+ L TL + NQL LP ++ + L S
Sbjct: 255 SGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTI-GNLSLLEEFDCSC 313
Query: 302 NAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQ 123
N + L P L +L T +D N L LP + S +N+T +SLR+NK+ + Q
Sbjct: 314 NELESL-PSTIGYLHSLRTLAVDENFLPELPREIGS-CKNVTVMSLRSNKLEFLPEEIGQ 371
Query: 122 GATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+R L+LS NRL P S ++ L +L L
Sbjct: 372 -MQKLRVLNLSDNRLKNLPFS-FTKLKELAAL 401
Score = 45.2 bits (102), Expect = 2e-04
Identities = 28/104 (26%), Positives = 57/104 (54%), Gaps = 1/104 (0%)
Frame = -3
Query: 365 RALPRSVLRGQTQLTS-LTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
R +P RG+ ++ S L S+ ++ ++ E+F R LE +D N+++ LP LF+
Sbjct: 15 RLVPCRCFRGEEEIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFN-C 73
Query: 188 RNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
+ L +S+ +N +S + T +++ LD+S N + P+++
Sbjct: 74 QALRKLSIPDNDLSNLP-TTIASLVNLKELDISKNGVQEFPENI 116
Score = 44.8 bits (101), Expect = 2e-04
Identities = 36/132 (27%), Positives = 59/132 (44%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L + +K+ +N LT+ NL L + + LP LRTL++ N
Sbjct: 280 LKKLTTLKVDDN-QLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENF 338
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
L LPR + +T ++L N + E PE ++ L + N L+ LP S F+ L
Sbjct: 339 LPELPREI-GSCKNVTVMSLRSNKL-EFLPEEIGQMQKLRVLNLSDNRLKNLPFS-FTKL 395
Query: 188 RNLTTVSLRNNK 153
+ L + L +N+
Sbjct: 396 KELAALWLSDNQ 407
Score = 41.9 bits (94), Expect = 0.002
Identities = 37/113 (32%), Positives = 54/113 (47%), Gaps = 1/113 (0%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L ++E S N +L + L +LRTL +D + + ELP E S + +SL N+
Sbjct: 303 LSLLEEFDCSCNELESLPSTI-GYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNK 361
Query: 368 LRALPRSVLRGQTQ-LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVL 213
L LP + GQ Q L L LS N + L P F L+ L + N+ + L
Sbjct: 362 LEFLPEEI--GQMQKLRVLNLSDNRLKNL-PFSFTKLKELAALWLSDNQSKAL 411
>AL158840-1|CAH70974.1| 1537|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1537
Score = 68.1 bits (159), Expect = 2e-11
Identities = 55/156 (35%), Positives = 76/156 (48%)
Frame = -3
Query: 485 FSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLS 306
F+ L L L L+ + + LP F LR L L N L+ LP+S+ + QL L L
Sbjct: 134 FTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHK-LAQLERLDLG 192
Query: 305 YNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTF 126
N EL PE+ ++ L MD N LQVLP S+ L+ L + + N+I + M+
Sbjct: 193 NNEFGEL-PEVLDQIQNLRELWMDNNALQVLPGSI-GKLKMLVYLDMSKNRIETVDMD-I 249
Query: 125 QGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTL 18
G ++ L LS N L PDS + L KL TL
Sbjct: 250 SGCEALEDLLLSSNMLQQLPDS----IGLLKKLTTL 281
Score = 58.4 bits (135), Expect = 2e-08
Identities = 49/152 (32%), Positives = 73/152 (48%)
Frame = -3
Query: 482 SNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSY 303
S AL L L + +++LP+ L TL + NQL LP ++ + L S
Sbjct: 250 SGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTI-GNLSLLEEFDCSC 308
Query: 302 NAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQ 123
N + L P L +L T +D N L LP + S +N+T +SLR+NK+ + Q
Sbjct: 309 NELESL-PSTIGYLHSLRTLAVDENFLPELPREIGS-CKNVTVMSLRSNKLEFLPEEIGQ 366
Query: 122 GATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+R L+LS NRL P S ++ L +L L
Sbjct: 367 -MQKLRVLNLSDNRLKNLPFS-FTKLKELAAL 396
Score = 45.2 bits (102), Expect = 2e-04
Identities = 28/104 (26%), Positives = 57/104 (54%), Gaps = 1/104 (0%)
Frame = -3
Query: 365 RALPRSVLRGQTQLTS-LTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
R +P RG+ ++ S L S+ ++ ++ E+F R LE +D N+++ LP LF+
Sbjct: 10 RLVPCRCFRGEEEIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFN-C 68
Query: 188 RNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
+ L +S+ +N +S + T +++ LD+S N + P+++
Sbjct: 69 QALRKLSIPDNDLSNLP-TTIASLVNLKELDISKNGVQEFPENI 111
Score = 44.8 bits (101), Expect = 2e-04
Identities = 36/132 (27%), Positives = 59/132 (44%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L + +K+ +N LT+ NL L + + LP LRTL++ N
Sbjct: 275 LKKLTTLKVDDN-QLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENF 333
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
L LPR + +T ++L N + E PE ++ L + N L+ LP S F+ L
Sbjct: 334 LPELPREI-GSCKNVTVMSLRSNKL-EFLPEEIGQMQKLRVLNLSDNRLKNLPFS-FTKL 390
Query: 188 RNLTTVSLRNNK 153
+ L + L +N+
Sbjct: 391 KELAALWLSDNQ 402
Score = 41.9 bits (94), Expect = 0.002
Identities = 37/113 (32%), Positives = 54/113 (47%), Gaps = 1/113 (0%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L ++E S N +L + L +LRTL +D + + ELP E S + +SL N+
Sbjct: 298 LSLLEEFDCSCNELESLPSTI-GYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNK 356
Query: 368 LRALPRSVLRGQTQ-LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVL 213
L LP + GQ Q L L LS N + L P F L+ L + N+ + L
Sbjct: 357 LEFLPEEI--GQMQKLRVLNLSDNRLKNL-PFSFTKLKELAALWLSDNQSKAL 406
>AL157948-2|CAI22426.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 68.1 bits (159), Expect = 2e-11
Identities = 55/156 (35%), Positives = 76/156 (48%)
Frame = -3
Query: 485 FSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLS 306
F+ L L L L+ + + LP F LR L L N L+ LP+S+ + QL L L
Sbjct: 139 FTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHK-LAQLERLDLG 197
Query: 305 YNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTF 126
N EL PE+ ++ L MD N LQVLP S+ L+ L + + N+I + M+
Sbjct: 198 NNEFGEL-PEVLDQIQNLRELWMDNNALQVLPGSI-GKLKMLVYLDMSKNRIETVDMD-I 254
Query: 125 QGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTL 18
G ++ L LS N L PDS + L KL TL
Sbjct: 255 SGCEALEDLLLSSNMLQQLPDS----IGLLKKLTTL 286
Score = 58.4 bits (135), Expect = 2e-08
Identities = 49/152 (32%), Positives = 73/152 (48%)
Frame = -3
Query: 482 SNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSY 303
S AL L L + +++LP+ L TL + NQL LP ++ + L S
Sbjct: 255 SGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTI-GNLSLLEEFDCSC 313
Query: 302 NAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQ 123
N + L P L +L T +D N L LP + S +N+T +SLR+NK+ + Q
Sbjct: 314 NELESL-PSTIGYLHSLRTLAVDENFLPELPREIGS-CKNVTVMSLRSNKLEFLPEEIGQ 371
Query: 122 GATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+R L+LS NRL P S ++ L +L L
Sbjct: 372 -MQKLRVLNLSDNRLKNLPFS-FTKLKELAAL 401
Score = 45.2 bits (102), Expect = 2e-04
Identities = 28/104 (26%), Positives = 57/104 (54%), Gaps = 1/104 (0%)
Frame = -3
Query: 365 RALPRSVLRGQTQLTS-LTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
R +P RG+ ++ S L S+ ++ ++ E+F R LE +D N+++ LP LF+
Sbjct: 15 RLVPCRCFRGEEEIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFN-C 73
Query: 188 RNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
+ L +S+ +N +S + T +++ LD+S N + P+++
Sbjct: 74 QALRKLSIPDNDLSNLP-TTIASLVNLKELDISKNGVQEFPENI 116
Score = 44.8 bits (101), Expect = 2e-04
Identities = 36/132 (27%), Positives = 59/132 (44%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L + +K+ +N LT+ NL L + + LP LRTL++ N
Sbjct: 280 LKKLTTLKVDDN-QLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENF 338
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
L LPR + +T ++L N + E PE ++ L + N L+ LP S F+ L
Sbjct: 339 LPELPREI-GSCKNVTVMSLRSNKL-EFLPEEIGQMQKLRVLNLSDNRLKNLPFS-FTKL 395
Query: 188 RNLTTVSLRNNK 153
+ L + L +N+
Sbjct: 396 KELAALWLSDNQ 407
Score = 41.9 bits (94), Expect = 0.002
Identities = 37/113 (32%), Positives = 54/113 (47%), Gaps = 1/113 (0%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L ++E S N +L + L +LRTL +D + + ELP E S + +SL N+
Sbjct: 303 LSLLEEFDCSCNELESLPSTI-GYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNK 361
Query: 368 LRALPRSVLRGQTQ-LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVL 213
L LP + GQ Q L L LS N + L P F L+ L + N+ + L
Sbjct: 362 LEFLPEEI--GQMQKLRVLNLSDNRLKNL-PFSFTKLKELAALWLSDNQSKAL 411
>AL157948-1|CAI22425.1| 1537|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1537
Score = 68.1 bits (159), Expect = 2e-11
Identities = 55/156 (35%), Positives = 76/156 (48%)
Frame = -3
Query: 485 FSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLS 306
F+ L L L L+ + + LP F LR L L N L+ LP+S+ + QL L L
Sbjct: 134 FTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHK-LAQLERLDLG 192
Query: 305 YNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTF 126
N EL PE+ ++ L MD N LQVLP S+ L+ L + + N+I + M+
Sbjct: 193 NNEFGEL-PEVLDQIQNLRELWMDNNALQVLPGSI-GKLKMLVYLDMSKNRIETVDMD-I 249
Query: 125 QGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTL 18
G ++ L LS N L PDS + L KL TL
Sbjct: 250 SGCEALEDLLLSSNMLQQLPDS----IGLLKKLTTL 281
Score = 58.4 bits (135), Expect = 2e-08
Identities = 49/152 (32%), Positives = 73/152 (48%)
Frame = -3
Query: 482 SNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSY 303
S AL L L + +++LP+ L TL + NQL LP ++ + L S
Sbjct: 250 SGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTI-GNLSLLEEFDCSC 308
Query: 302 NAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQ 123
N + L P L +L T +D N L LP + S +N+T +SLR+NK+ + Q
Sbjct: 309 NELESL-PSTIGYLHSLRTLAVDENFLPELPREIGS-CKNVTVMSLRSNKLEFLPEEIGQ 366
Query: 122 GATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+R L+LS NRL P S ++ L +L L
Sbjct: 367 -MQKLRVLNLSDNRLKNLPFS-FTKLKELAAL 396
Score = 45.2 bits (102), Expect = 2e-04
Identities = 28/104 (26%), Positives = 57/104 (54%), Gaps = 1/104 (0%)
Frame = -3
Query: 365 RALPRSVLRGQTQLTS-LTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
R +P RG+ ++ S L S+ ++ ++ E+F R LE +D N+++ LP LF+
Sbjct: 10 RLVPCRCFRGEEEIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFN-C 68
Query: 188 RNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
+ L +S+ +N +S + T +++ LD+S N + P+++
Sbjct: 69 QALRKLSIPDNDLSNLP-TTIASLVNLKELDISKNGVQEFPENI 111
Score = 44.8 bits (101), Expect = 2e-04
Identities = 36/132 (27%), Positives = 59/132 (44%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L + +K+ +N LT+ NL L + + LP LRTL++ N
Sbjct: 275 LKKLTTLKVDDN-QLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENF 333
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
L LPR + +T ++L N + E PE ++ L + N L+ LP S F+ L
Sbjct: 334 LPELPREI-GSCKNVTVMSLRSNKL-EFLPEEIGQMQKLRVLNLSDNRLKNLPFS-FTKL 390
Query: 188 RNLTTVSLRNNK 153
+ L + L +N+
Sbjct: 391 KELAALWLSDNQ 402
Score = 41.9 bits (94), Expect = 0.002
Identities = 37/113 (32%), Positives = 54/113 (47%), Gaps = 1/113 (0%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L ++E S N +L + L +LRTL +D + + ELP E S + +SL N+
Sbjct: 298 LSLLEEFDCSCNELESLPSTI-GYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNK 356
Query: 368 LRALPRSVLRGQTQ-LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVL 213
L LP + GQ Q L L LS N + L P F L+ L + N+ + L
Sbjct: 357 LEFLPEEI--GQMQKLRVLNLSDNRLKNL-PFSFTKLKELAALWLSDNQSKAL 406
>AL117353-1|CAI23423.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 68.1 bits (159), Expect = 2e-11
Identities = 55/156 (35%), Positives = 76/156 (48%)
Frame = -3
Query: 485 FSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLS 306
F+ L L L L+ + + LP F LR L L N L+ LP+S+ + QL L L
Sbjct: 139 FTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHK-LAQLERLDLG 197
Query: 305 YNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTF 126
N EL PE+ ++ L MD N LQVLP S+ L+ L + + N+I + M+
Sbjct: 198 NNEFGEL-PEVLDQIQNLRELWMDNNALQVLPGSI-GKLKMLVYLDMSKNRIETVDMD-I 254
Query: 125 QGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTL 18
G ++ L LS N L PDS + L KL TL
Sbjct: 255 SGCEALEDLLLSSNMLQQLPDS----IGLLKKLTTL 286
Score = 58.4 bits (135), Expect = 2e-08
Identities = 49/152 (32%), Positives = 73/152 (48%)
Frame = -3
Query: 482 SNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSY 303
S AL L L + +++LP+ L TL + NQL LP ++ + L S
Sbjct: 255 SGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTI-GNLSLLEEFDCSC 313
Query: 302 NAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQ 123
N + L P L +L T +D N L LP + S +N+T +SLR+NK+ + Q
Sbjct: 314 NELESL-PSTIGYLHSLRTLAVDENFLPELPREIGS-CKNVTVMSLRSNKLEFLPEEIGQ 371
Query: 122 GATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+R L+LS NRL P S ++ L +L L
Sbjct: 372 -MQKLRVLNLSDNRLKNLPFS-FTKLKELAAL 401
Score = 45.2 bits (102), Expect = 2e-04
Identities = 28/104 (26%), Positives = 57/104 (54%), Gaps = 1/104 (0%)
Frame = -3
Query: 365 RALPRSVLRGQTQLTS-LTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
R +P RG+ ++ S L S+ ++ ++ E+F R LE +D N+++ LP LF+
Sbjct: 15 RLVPCRCFRGEEEIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFN-C 73
Query: 188 RNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
+ L +S+ +N +S + T +++ LD+S N + P+++
Sbjct: 74 QALRKLSIPDNDLSNLP-TTIASLVNLKELDISKNGVQEFPENI 116
Score = 44.8 bits (101), Expect = 2e-04
Identities = 36/132 (27%), Positives = 59/132 (44%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L + +K+ +N LT+ NL L + + LP LRTL++ N
Sbjct: 280 LKKLTTLKVDDN-QLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENF 338
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
L LPR + +T ++L N + E PE ++ L + N L+ LP S F+ L
Sbjct: 339 LPELPREI-GSCKNVTVMSLRSNKL-EFLPEEIGQMQKLRVLNLSDNRLKNLPFS-FTKL 395
Query: 188 RNLTTVSLRNNK 153
+ L + L +N+
Sbjct: 396 KELAALWLSDNQ 407
Score = 41.9 bits (94), Expect = 0.002
Identities = 37/113 (32%), Positives = 54/113 (47%), Gaps = 1/113 (0%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L ++E S N +L + L +LRTL +D + + ELP E S + +SL N+
Sbjct: 303 LSLLEEFDCSCNELESLPSTI-GYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNK 361
Query: 368 LRALPRSVLRGQTQ-LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVL 213
L LP + GQ Q L L LS N + L P F L+ L + N+ + L
Sbjct: 362 LEFLPEEI--GQMQKLRVLNLSDNRLKNL-PFSFTKLKELAALWLSDNQSKAL 411
>AF434715-1|AAL28133.1| 1537|Homo sapiens densin-180 protein.
Length = 1537
Score = 68.1 bits (159), Expect = 2e-11
Identities = 55/156 (35%), Positives = 76/156 (48%)
Frame = -3
Query: 485 FSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLS 306
F+ L L L L+ + + LP F LR L L N L+ LP+S+ + QL L L
Sbjct: 134 FTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHK-LAQLERLDLG 192
Query: 305 YNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTF 126
N EL PE+ ++ L MD N LQVLP S+ L+ L + + N+I + M+
Sbjct: 193 NNEFGEL-PEVLDQIQNLRELWMDNNALQVLPGSI-GKLKMLVYLDMSKNRIETVDMD-I 249
Query: 125 QGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTL 18
G ++ L LS N L PDS + L KL TL
Sbjct: 250 SGCEALEDLLLSSNMLQQLPDS----IGLLKKLTTL 281
Score = 58.4 bits (135), Expect = 2e-08
Identities = 49/152 (32%), Positives = 73/152 (48%)
Frame = -3
Query: 482 SNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSY 303
S AL L L + +++LP+ L TL + NQL LP ++ + L S
Sbjct: 250 SGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTI-GNLSLLEEFDCSC 308
Query: 302 NAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQ 123
N + L P L +L T +D N L LP + S +N+T +SLR+NK+ + Q
Sbjct: 309 NELESL-PSTIGYLHSLRTLAVDENFLPELPREIGS-CKNVTVMSLRSNKLEFLPEEIGQ 366
Query: 122 GATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+R L+LS NRL P S ++ L +L L
Sbjct: 367 -MQKLRVLNLSDNRLKNLPFS-FTKLKELAAL 396
Score = 45.2 bits (102), Expect = 2e-04
Identities = 28/104 (26%), Positives = 57/104 (54%), Gaps = 1/104 (0%)
Frame = -3
Query: 365 RALPRSVLRGQTQLTS-LTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
R +P RG+ ++ S L S+ ++ ++ E+F R LE +D N+++ LP LF+
Sbjct: 10 RLVPCRCFRGEEEIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFN-C 68
Query: 188 RNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
+ L +S+ +N +S + T +++ LD+S N + P+++
Sbjct: 69 QALRKLSIPDNDLSNLP-TTIASLVNLKELDISKNGVQEFPENI 111
Score = 44.8 bits (101), Expect = 2e-04
Identities = 36/132 (27%), Positives = 59/132 (44%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L + +K+ +N LT+ NL L + + LP LRTL++ N
Sbjct: 275 LKKLTTLKVDDN-QLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENF 333
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
L LPR + +T ++L N + E PE ++ L + N L+ LP S F+ L
Sbjct: 334 LPELPREI-GSCKNVTVMSLRSNKL-EFLPEEIGQMQKLRVLNLSDNRLKNLPFS-FTKL 390
Query: 188 RNLTTVSLRNNK 153
+ L + L +N+
Sbjct: 391 KELAALWLSDNQ 402
Score = 41.9 bits (94), Expect = 0.002
Identities = 37/113 (32%), Positives = 54/113 (47%), Gaps = 1/113 (0%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L ++E S N +L + L +LRTL +D + + ELP E S + +SL N+
Sbjct: 298 LSLLEEFDCSCNELESLPSTI-GYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNK 356
Query: 368 LRALPRSVLRGQTQ-LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVL 213
L LP + GQ Q L L LS N + L P F L+ L + N+ + L
Sbjct: 357 LEFLPEEI--GQMQKLRVLNLSDNRLKNL-PFSFTKLKELAALWLSDNQSKAL 406
>AF276423-1|AAK69431.1| 1412|Homo sapiens densin-180-like protein
protein.
Length = 1412
Score = 68.1 bits (159), Expect = 2e-11
Identities = 61/199 (30%), Positives = 90/199 (45%)
Frame = -3
Query: 602 FTMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP 423
F M N ++ I L + + +S N ++E + S L+ L L +S+++LP
Sbjct: 212 FWMDANRLTFIPGFI-GSLKQLTYLDVSKNNIEMVEEGI-STCENLQDLLLSSNSLQQLP 269
Query: 422 EEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETF 243
E S + TL + NQL LP S+ G + L S+N V E P L L TF
Sbjct: 270 ETIGSLKNITTLKIDENQLMYLPDSI-GGLISVEELDCSFNEV-EALPSSIGQLTNLRTF 327
Query: 242 VMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPD 63
D N LQ LP + S +N+T + L +NK+ + ++ ++LS NRL P
Sbjct: 328 AADHNYLQQLPPEIGS-WKNITVLFLHSNKLETLP-EEMGDMQKLKVINLSDNRLKNLPF 385
Query: 62 SLYSPLNQLHKLQTLTLAW 6
S KLQ LT W
Sbjct: 386 S-------FTKLQQLTAMW 397
Score = 64.1 bits (149), Expect = 4e-10
Identities = 51/162 (31%), Positives = 76/162 (46%)
Frame = -3
Query: 488 VFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTL 309
+F+ L L LD + I ELP++ + L LSL N L LP S+ L L +
Sbjct: 41 IFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASI-ANLINLRELDV 99
Query: 308 SYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNT 129
S N + E PE + + L N + LPD FS L NLT + L + + + N
Sbjct: 100 SKNGIQEF-PENIKNCKVLTIVEASVNPISKLPDG-FSQLLNLTQLYLNDAFLEFLPAN- 156
Query: 128 FQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
F T ++ L+L N+L P + +N+L +L+ L L N
Sbjct: 157 FGRLTKLQILELRENQLKMLPKT----MNRLTQLERLDLGSN 194
Score = 62.9 bits (146), Expect = 8e-10
Identities = 48/148 (32%), Positives = 72/148 (48%)
Frame = -3
Query: 485 FSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLS 306
FS L L L L+ + + LP F + L+ L L NQL+ LP+++ R TQL L L
Sbjct: 134 FSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNR-LTQLERLDLG 192
Query: 305 YNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTF 126
N E+ PE+ L L+ F MD N L +P L+ LT + + N I ++
Sbjct: 193 SNEFTEV-PEVLEQLSGLKEFWMDANRLTFIP-GFIGSLKQLTYLDVSKNNIEMVE-EGI 249
Query: 125 QGATSIRTLDLSYNRLAFAPDSLYSPLN 42
+++ L LS N L P+++ S N
Sbjct: 250 STCENLQDLLLSSNSLQQLPETIGSLKN 277
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/105 (26%), Positives = 61/105 (58%), Gaps = 1/105 (0%)
Frame = -3
Query: 368 LRALPRSVLRGQTQ-LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSG 192
+R +P LRG+ + +T+L S+ ++ ++ E+F + LE +D N+++ LP LF+
Sbjct: 9 VRLVPCRCLRGEEETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFN- 67
Query: 191 LRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
++L +SL +N ++ + + ++R LD+S N + P+++
Sbjct: 68 CQSLHKLSLPDNDLTTLPA-SIANLINLRELDVSKNGIQEFPENI 111
>AF263744-1|AAF77048.1| 1371|Homo sapiens erbb2-interacting protein
ERBIN protein.
Length = 1371
Score = 68.1 bits (159), Expect = 2e-11
Identities = 61/199 (30%), Positives = 90/199 (45%)
Frame = -3
Query: 602 FTMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP 423
F M N ++ I L + + +S N ++E + S L+ L L +S+++LP
Sbjct: 212 FWMDANRLTFIPGFI-GSLKQLTYLDVSKNNIEMVEEGI-STCENLQDLLLSSNSLQQLP 269
Query: 422 EEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETF 243
E S + TL + NQL LP S+ G + L S+N V E P L L TF
Sbjct: 270 ETIGSLKNITTLKIDENQLMYLPDSI-GGLISVEELDCSFNEV-EALPSSIGQLTNLRTF 327
Query: 242 VMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPD 63
D N LQ LP + S +N+T + L +NK+ + ++ ++LS NRL P
Sbjct: 328 AADHNYLQQLPPEIGS-WKNITVLFLHSNKLETLP-EEMGDMQKLKVINLSDNRLKNLPF 385
Query: 62 SLYSPLNQLHKLQTLTLAW 6
S KLQ LT W
Sbjct: 386 S-------FTKLQQLTAMW 397
Score = 64.1 bits (149), Expect = 4e-10
Identities = 51/162 (31%), Positives = 76/162 (46%)
Frame = -3
Query: 488 VFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTL 309
+F+ L L LD + I ELP++ + L LSL N L LP S+ L L +
Sbjct: 41 IFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASI-ANLINLRELDV 99
Query: 308 SYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNT 129
S N + E PE + + L N + LPD FS L NLT + L + + + N
Sbjct: 100 SKNGIQEF-PENIKNCKVLTIVEASVNPISKLPDG-FSQLLNLTQLYLNDAFLEFLPAN- 156
Query: 128 FQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
F T ++ L+L N+L P + +N+L +L+ L L N
Sbjct: 157 FGRLTKLQILELRENQLKMLPKT----MNRLTQLERLDLGSN 194
Score = 62.9 bits (146), Expect = 8e-10
Identities = 48/148 (32%), Positives = 72/148 (48%)
Frame = -3
Query: 485 FSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLS 306
FS L L L L+ + + LP F + L+ L L NQL+ LP+++ R TQL L L
Sbjct: 134 FSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNR-LTQLERLDLG 192
Query: 305 YNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTF 126
N E+ PE+ L L+ F MD N L +P L+ LT + + N I ++
Sbjct: 193 SNEFTEV-PEVLEQLSGLKEFWMDANRLTFIP-GFIGSLKQLTYLDVSKNNIEMVE-EGI 249
Query: 125 QGATSIRTLDLSYNRLAFAPDSLYSPLN 42
+++ L LS N L P+++ S N
Sbjct: 250 STCENLQDLLLSSNSLQQLPETIGSLKN 277
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/105 (26%), Positives = 61/105 (58%), Gaps = 1/105 (0%)
Frame = -3
Query: 368 LRALPRSVLRGQTQ-LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSG 192
+R +P LRG+ + +T+L S+ ++ ++ E+F + LE +D N+++ LP LF+
Sbjct: 9 VRLVPCRCLRGEEETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFN- 67
Query: 191 LRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
++L +SL +N ++ + + ++R LD+S N + P+++
Sbjct: 68 CQSLHKLSLPDNDLTTLPA-SIANLINLRELDVSKNGIQEFPENI 111
>AB033051-1|BAA86539.2| 1371|Homo sapiens KIAA1225 protein protein.
Length = 1371
Score = 68.1 bits (159), Expect = 2e-11
Identities = 61/199 (30%), Positives = 90/199 (45%)
Frame = -3
Query: 602 FTMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP 423
F M N ++ I L + + +S N ++E + S L+ L L +S+++LP
Sbjct: 212 FWMDANRLTFIPGFI-GSLKQLTYLDVSKNNIEMVEEGI-STCENLQDLLLSSNSLQQLP 269
Query: 422 EEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETF 243
E S + TL + NQL LP S+ G + L S+N V E P L L TF
Sbjct: 270 ETIGSLKNITTLKIDENQLMYLPDSI-GGLISVEELDCSFNEV-EALPSSIGQLTNLRTF 327
Query: 242 VMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPD 63
D N LQ LP + S +N+T + L +NK+ + ++ ++LS NRL P
Sbjct: 328 AADHNYLQQLPPEIGS-WKNITVLFLHSNKLETLP-EEMGDMQKLKVINLSDNRLKNLPF 385
Query: 62 SLYSPLNQLHKLQTLTLAW 6
S KLQ LT W
Sbjct: 386 S-------FTKLQQLTAMW 397
Score = 64.1 bits (149), Expect = 4e-10
Identities = 51/162 (31%), Positives = 76/162 (46%)
Frame = -3
Query: 488 VFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTL 309
+F+ L L LD + I ELP++ + L LSL N L LP S+ L L +
Sbjct: 41 IFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASI-ANLINLRELDV 99
Query: 308 SYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNT 129
S N + E PE + + L N + LPD FS L NLT + L + + + N
Sbjct: 100 SKNGIQEF-PENIKNCKVLTIVEASVNPISKLPDG-FSQLLNLTQLYLNDAFLEFLPAN- 156
Query: 128 FQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
F T ++ L+L N+L P + +N+L +L+ L L N
Sbjct: 157 FGRLTKLQILELRENQLKMLPKT----MNRLTQLERLDLGSN 194
Score = 62.9 bits (146), Expect = 8e-10
Identities = 48/148 (32%), Positives = 72/148 (48%)
Frame = -3
Query: 485 FSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLS 306
FS L L L L+ + + LP F + L+ L L NQL+ LP+++ R TQL L L
Sbjct: 134 FSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNR-LTQLERLDLG 192
Query: 305 YNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTF 126
N E+ PE+ L L+ F MD N L +P L+ LT + + N I ++
Sbjct: 193 SNEFTEV-PEVLEQLSGLKEFWMDANRLTFIP-GFIGSLKQLTYLDVSKNNIEMVE-EGI 249
Query: 125 QGATSIRTLDLSYNRLAFAPDSLYSPLN 42
+++ L LS N L P+++ S N
Sbjct: 250 STCENLQDLLLSSNSLQQLPETIGSLKN 277
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/105 (26%), Positives = 61/105 (58%), Gaps = 1/105 (0%)
Frame = -3
Query: 368 LRALPRSVLRGQTQ-LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSG 192
+R +P LRG+ + +T+L S+ ++ ++ E+F + LE +D N+++ LP LF+
Sbjct: 9 VRLVPCRCLRGEEETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFN- 67
Query: 191 LRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
++L +SL +N ++ + + ++R LD+S N + P+++
Sbjct: 68 CQSLHKLSLPDNDLTTLPA-SIANLINLRELDVSKNGIQEFPENI 111
>BC058935-1|AAH58935.1| 239|Homo sapiens LRRC57 protein protein.
Length = 239
Score = 67.3 bits (157), Expect = 4e-11
Identities = 51/166 (30%), Positives = 85/166 (51%), Gaps = 2/166 (1%)
Frame = -3
Query: 542 HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLR 363
+++ I +SNN +L + L++L L+ + + LP+E + L TLSL N LR
Sbjct: 39 NLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLTVLPDEICNLKKLETLSLNNNHLR 98
Query: 362 ALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRN 183
LP S + L +L+LS N + L P+L LR L+ + N+++ +PDS+ G
Sbjct: 99 ELP-STFGQLSALKTLSLSGNQLGALPPQL-CSLRHLDVMDLSKNQIRSIPDSV--GELQ 154
Query: 182 LTTVSLRNNKISVISMNTFQGATSIRTLDLSYN--RLAFAPDSLYS 51
+ ++L N+IS IS+ ++ L L N L+ P S+ S
Sbjct: 155 VIELNLNQNQISQISVK-ISCCPRLKILRLEENCLELSMLPQSILS 199
Score = 61.3 bits (142), Expect = 3e-09
Identities = 43/134 (32%), Positives = 70/134 (52%), Gaps = 1/134 (0%)
Frame = -3
Query: 455 QLDLSSIRELPEEFIS-NSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAP 279
QL + E P + S LRT+ L+ N++ +LP ++ T L SL+L+ N + L P
Sbjct: 20 QLKDRGLTEFPADLQKLTSNLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLTVL-P 78
Query: 278 ELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTL 99
+ +L+ LET ++ N L+ LP S F L L T+SL N++ + + +
Sbjct: 79 DEICNLKKLETLSLNNNHLRELP-STFGQLSALKTLSLSGNQLGALPPQ-LCSLRHLDVM 136
Query: 98 DLSYNRLAFAPDSL 57
DLS N++ PDS+
Sbjct: 137 DLSKNQIRSIPDSV 150
Score = 36.7 bits (81), Expect = 0.063
Identities = 25/78 (32%), Positives = 37/78 (47%)
Frame = -3
Query: 245 FVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAP 66
F + L P L NL T+ L NNKI + T +++L L+ N+L P
Sbjct: 19 FQLKDRGLTEFPADLQKLTSNLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLTVLP 78
Query: 65 DSLYSPLNQLHKLQTLTL 12
D + + L KL+TL+L
Sbjct: 79 DEICN----LKKLETLSL 92
>AY358284-1|AAQ88651.1| 620|Homo sapiens QVSK201 protein.
Length = 620
Score = 67.3 bits (157), Expect = 4e-11
Identities = 37/123 (30%), Positives = 64/123 (52%)
Frame = -3
Query: 395 RTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 216
R L L +N+++ L + L L L+ N V+ + P F +L L T + N L++
Sbjct: 74 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKL 133
Query: 215 LPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQL 36
+P +F+GL NLT + NKI ++ FQ ++++L++ N L + +S LN L
Sbjct: 134 IPLGVFTGLSNLTKQDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSL 193
Query: 35 HKL 27
+L
Sbjct: 194 EQL 196
Score = 63.7 bits (148), Expect = 5e-10
Identities = 40/169 (23%), Positives = 83/169 (49%), Gaps = 1/169 (0%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP-EEF 414
+N + L+ + F H++E++++ N+ ++ F+NL LRTL L + ++ +P F
Sbjct: 80 KNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVF 139
Query: 413 ISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 234
S L ++ N++ L + + L SL + N + ++ F+ L +LE ++
Sbjct: 140 TGLSNLTKQDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLE 199
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSY 87
L +P S L L + LR+ I+ I +F+ ++ L++S+
Sbjct: 200 KCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISH 248
Score = 61.7 bits (143), Expect = 2e-09
Identities = 44/170 (25%), Positives = 78/170 (45%), Gaps = 1/170 (0%)
Frame = -3
Query: 530 IKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRALP 354
+ + N TL + F++ P L L+L+ + + + P F + LRTL L N+L+ +P
Sbjct: 76 LDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIP 135
Query: 353 RSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTT 174
V G + LT +S N + L +F DL L++ + N+L + FSGL +L
Sbjct: 136 LGVFTGLSNLTKQDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQ 195
Query: 173 VSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
++L ++ I + L L + + D + L +L L+
Sbjct: 196 LTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLE 245
Score = 53.6 bits (123), Expect = 5e-07
Identities = 28/103 (27%), Positives = 51/103 (49%)
Frame = -3
Query: 332 TQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNK 153
T+ L L N + L + FA LE ++ N + + F+ L NL T+ LR+N+
Sbjct: 71 TETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNR 130
Query: 152 ISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
+ +I + F G +++ D+S N++ D ++ L L L+
Sbjct: 131 LKLIPLGVFTGLSNLTKQDISENKIVILLDYMFQDLYNLKSLE 173
Score = 53.2 bits (122), Expect = 7e-07
Identities = 30/108 (27%), Positives = 53/108 (49%)
Frame = -3
Query: 398 LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 219
L +LS+ L A+P +R L L LSYN ++ + + +L L+ + G +L
Sbjct: 265 LTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLA 324
Query: 218 VLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLA 75
V+ F GL L +++ N+++ + + F ++ TL L N LA
Sbjct: 325 VVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPLA 372
Score = 50.0 bits (114), Expect = 6e-06
Identities = 45/192 (23%), Positives = 92/192 (47%), Gaps = 4/192 (2%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N + + +F GL ++ + IS N + L + +F +L L++L++ + + + S
Sbjct: 129 NRLKLIPLGVFTGLSNLTKQDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFS 188
Query: 407 N-SPLRTLSLARNQLRALPR---SVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+ L L+L + L ++P S L G L L+ NA+ + + + L+ LE +
Sbjct: 189 GLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLE--I 246
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
L + + GL NLT++S+ + ++ + + +R L+LSYN ++ S
Sbjct: 247 SHWPYLDTMTPNCLYGL-NLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGS 305
Query: 59 LYSPLNQLHKLQ 24
+ L +L ++Q
Sbjct: 306 MLHELLRLQEIQ 317
>AL513211-2|CAI17359.1| 154|Homo sapiens leucine rich repeat
containing 1 protein.
Length = 154
Score = 67.3 bits (157), Expect = 4e-11
Identities = 46/136 (33%), Positives = 74/136 (54%)
Frame = -3
Query: 542 HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLR 363
H++ I + + + E ++ +L L LD + +RELPE+F LR L L+ N+++
Sbjct: 13 HVESIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQ 72
Query: 362 ALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRN 183
LP + QL L +S N + E+ PE + +AL+ GN L LP+S F L+N
Sbjct: 73 RLPPEIANFM-QLVELDVSRNEIPEI-PESISFCKALQVADFSGNPLTRLPES-FPELQN 129
Query: 182 LTTVSLRNNKISVISM 135
LT +S+ N IS+ S+
Sbjct: 130 LTCLSV--NDISLQSL 143
Score = 35.1 bits (77), Expect = 0.19
Identities = 23/95 (24%), Positives = 46/95 (48%)
Frame = -3
Query: 341 RGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLR 162
R + S+ + ++ + E++ R+LE ++D N+L+ LP+ F L L + L
Sbjct: 9 RCNRHVESIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQ-LVKLRKLGLS 67
Query: 161 NNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
+N+I + + LD+S N + P+S+
Sbjct: 68 DNEIQRLPPE-IANFMQLVELDVSRNEIPEIPESI 101
>AL356953-5|CAI15931.1| 232|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 232
Score = 67.3 bits (157), Expect = 4e-11
Identities = 51/164 (31%), Positives = 78/164 (47%), Gaps = 1/164 (0%)
Frame = -3
Query: 500 LKEAVFSNLPALRTLQLDLSSIRELPEEFISNS-PLRTLSLARNQLRALPRSVLRGQTQL 324
L+ +F +L L L+L + + +P + S L+ L L NQL +P L L
Sbjct: 7 LQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSL 66
Query: 323 TSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISV 144
SL L N ++ + F L +L +D N L +P + L L ++L N+IS
Sbjct: 67 QSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISH 126
Query: 143 ISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTL 12
I FQ TS+ LDL+YN+L P + + L +LQ L+L
Sbjct: 127 IPDYAFQNLTSLVVLDLNYNKLQEFPVA----IRTLGRLQELSL 166
Score = 66.9 bits (156), Expect = 5e-11
Identities = 53/196 (27%), Positives = 93/196 (47%), Gaps = 1/196 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFI 411
N ++ + F GL ++ + + NN + LP+L++L+LD + I +PE F
Sbjct: 26 NHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFE 85
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
S LR L L N L +P L L ++TL+ N ++ + F +L +L ++
Sbjct: 86 GLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLDLNY 145
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N+LQ P ++ + L L +SL N + + +G TS+ L L+ + P +
Sbjct: 146 NKLQEFPVAIRT-LGRLQELSL-NGAMDIQEFPDLKGTTSLEILTLTRAGIRLLPSGM-- 201
Query: 50 PLNQLHKLQTLTLAWN 3
QL +L+ L L+ N
Sbjct: 202 -CQQLPRLRVLELSHN 216
Score = 56.8 bits (131), Expect = 5e-08
Identities = 31/92 (33%), Positives = 47/92 (51%)
Frame = -3
Query: 302 NAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQ 123
N + EL P LF LR LE + GN L +P FSGL +L + L+NN++ I
Sbjct: 2 NNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALW 61
Query: 122 GATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
S+++L L N ++ P+ + L+ L L
Sbjct: 62 ELPSLQSLRLDANLISLVPERSFEGLSSLRHL 93
Score = 52.8 bits (121), Expect = 9e-07
Identities = 38/124 (30%), Positives = 60/124 (48%)
Frame = -3
Query: 374 NQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFS 195
N L L + L L LS N ++ + + F+ L +L+ ++ N+L +P
Sbjct: 2 NNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALW 61
Query: 194 GLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLT 15
L +L ++ L N IS++ +F+G +S+R L L N L P LN L LQ +T
Sbjct: 62 ELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIP---VRALNNLPALQAMT 118
Query: 14 LAWN 3
LA N
Sbjct: 119 LALN 122
Score = 47.2 bits (107), Expect = 4e-05
Identities = 35/137 (25%), Positives = 66/137 (48%), Gaps = 1/137 (0%)
Frame = -3
Query: 557 FRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSL 381
F GL ++ + + +N + +NLPAL+ + L L+ I +P+ N + L L L
Sbjct: 84 FEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLDL 143
Query: 380 ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSL 201
N+L+ P ++ R +L L+L+ + P+L +LE + +++LP +
Sbjct: 144 NYNKLQEFPVAI-RTLGRLQELSLNGAMDIQEFPDL-KGTTSLEILTLTRAGIRLLPSGM 201
Query: 200 FSGLRNLTTVSLRNNKI 150
L L + L +N+I
Sbjct: 202 CQQLPRLRVLELSHNQI 218
Score = 37.1 bits (82), Expect = 0.047
Identities = 30/127 (23%), Positives = 55/127 (43%), Gaps = 1/127 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N+ + L +Q + ++ N + + F NL +L L L+ + ++E P +
Sbjct: 98 NALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLDLNYNKLQEFPVAIRT 157
Query: 407 NSPLRTLSL-ARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 231
L+ LSL ++ P L+G T L LTL+ + L + L L +
Sbjct: 158 LGRLQELSLNGAMDIQEFPD--LKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSH 215
Query: 230 NELQVLP 210
N+++ LP
Sbjct: 216 NQIEELP 222
>AL158163-3|CAH72813.1| 372|Homo sapiens soc-2 suppressor of clear
homolog (C. elegans) protein.
Length = 372
Score = 67.3 bits (157), Expect = 4e-11
Identities = 47/176 (26%), Positives = 91/176 (51%), Gaps = 2/176 (1%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKE--AVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLAR 375
LD+++++++ + L+E +V L +L TL L + I + ++ + S L LS+
Sbjct: 1 LDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRE 60
Query: 374 NQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFS 195
N+++ LP + + L+ L L YN ++ + P A ALE ++ N + LP+SL S
Sbjct: 61 NKIKQLPAEI-GNLSSLSRLGLRYNRLSAI-PRSLAKCSALEELNLENNNISTLPESLLS 118
Query: 194 GLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
L L +++L N + + ++I +L++ +NR+ P ++S L KL
Sbjct: 119 SLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKL 174
Score = 56.8 bits (131), Expect = 5e-08
Identities = 50/191 (26%), Positives = 88/191 (46%)
Frame = -3
Query: 599 TMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE 420
T+ RN F+ I + + +N + +FS L L + + + LP
Sbjct: 127 TLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPL 186
Query: 419 EFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+F + + + L+LA NQL +P V G L L LS N + +L P +LR L
Sbjct: 187 DFGTWTSMVELNLATNQLTKIPEDV-SGLVSLEVLILSNNLLKKL-PHGLGNLRKLRELD 244
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
++ N+L+ LP+ + + L++L + L NN+++ + T++ L L N L P+
Sbjct: 245 LEENKLESLPNEI-AYLKDLQKLVLTNNQLTTLPRG-IGHLTNLTHLGLGENLLTHLPEE 302
Query: 59 LYSPLNQLHKL 27
+ L L +L
Sbjct: 303 I-GTLENLEEL 312
Score = 53.2 bits (122), Expect = 7e-07
Identities = 47/148 (31%), Positives = 67/148 (45%), Gaps = 1/148 (0%)
Frame = -3
Query: 551 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARN 372
GL ++ + +SNN+ L + NL LR L L+ + + LP E L+ L L N
Sbjct: 213 GLVSLEVLILSNNLLKKLPHGL-GNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNN 271
Query: 371 QLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN-ELQVLPDSLFS 195
QL LPR + T LT L L N + L PE L LE ++ N L LP L +
Sbjct: 272 QLTTLPRGI-GHLTNLTHLGLGENLLTHL-PEEIGTLENLEELYLNDNPNLHSLPFEL-A 328
Query: 194 GLRNLTTVSLRNNKISVISMNTFQGATS 111
L+ +S+ N +S + G S
Sbjct: 329 LCSKLSIMSIENCPLSHLPPQIVAGGPS 356
>AL122074-1|CAB59249.1| 333|Homo sapiens hypothetical protein
protein.
Length = 333
Score = 67.3 bits (157), Expect = 4e-11
Identities = 36/103 (34%), Positives = 60/103 (58%)
Frame = -3
Query: 311 LSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMN 132
+S N ++++AP+ F L++L + V+ GN++ + LF GL +L + L NKI+ + +N
Sbjct: 13 ISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVN 72
Query: 131 TFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
TFQ ++ L L N+L L++P L +QTL LA N
Sbjct: 73 TFQDLQNLNLLSLYDNKLQTISKGLFAP---LQSIQTLHLAQN 112
Score = 64.1 bits (149), Expect = 4e-10
Identities = 34/100 (34%), Positives = 56/100 (56%)
Frame = -3
Query: 383 LARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDS 204
+++NQ+ + +G LTSL L N + E+A LF L +L+ +++ N++ L +
Sbjct: 13 ISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVN 72
Query: 203 LFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
F L+NL +SL +NK+ IS F SI+TL L+ N
Sbjct: 73 TFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQN 112
Score = 58.8 bits (136), Expect = 1e-08
Identities = 34/119 (28%), Positives = 60/119 (50%), Gaps = 1/119 (0%)
Frame = -3
Query: 389 LSLARNQLRALPRS-VLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVL 213
L L N++ L + + + L + LS N + E+ F +++ ++ GN+L+ +
Sbjct: 212 LRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETV 271
Query: 212 PDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQL 36
+F GL L T+ LR+N I +S +TF G +S+R L L NR+ ++ L L
Sbjct: 272 HGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSL 330
Score = 48.0 bits (109), Expect = 3e-05
Identities = 24/100 (24%), Positives = 52/100 (52%)
Frame = -3
Query: 398 LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 219
LR ++L+ N+++ + G + L L+ N + + +F L L+T ++ N +
Sbjct: 234 LRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIG 293
Query: 218 VLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTL 99
+ + F+GL ++ +SL +N+I+ I+ F S+ T+
Sbjct: 294 CVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTM 333
Score = 42.3 bits (95), Expect = 0.001
Identities = 29/86 (33%), Positives = 44/86 (51%), Gaps = 1/86 (1%)
Frame = -3
Query: 281 PELFADLRALETFVMDGNELQVLPDS-LFSGLRNLTTVSLRNNKISVISMNTFQGATSIR 105
PE DLR ++ NE+ VL + +F L NL ++L NNKI + F GA S++
Sbjct: 206 PEYVTDLR------LNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQ 259
Query: 104 TLDLSYNRLAFAPDSLYSPLNQLHKL 27
L L+ N+L ++ L+ L L
Sbjct: 260 ELMLTGNQLETVHGRVFRGLSGLKTL 285
Score = 41.9 bits (94), Expect = 0.002
Identities = 27/106 (25%), Positives = 50/106 (47%), Gaps = 1/106 (0%)
Frame = -3
Query: 560 IFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLS 384
IF+ L ++++I +SNN ++E F +++ L L + + + F S L+TL
Sbjct: 227 IFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLM 286
Query: 383 LARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALET 246
L N + + G + + L+L N + + P F L +L T
Sbjct: 287 LRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLST 332
Score = 39.1 bits (87), Expect = 0.012
Identities = 23/101 (22%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
Frame = -3
Query: 326 LTSLTLSYNAVAEL-APELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKI 150
+T L L+ N V+ L A +F L L + N+++ + + F G ++ + L N++
Sbjct: 209 VTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQL 268
Query: 149 SVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+ F+G + ++TL L N + + ++ L+ + L
Sbjct: 269 ETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLL 309
>AK094891-1|BAC04451.1| 239|Homo sapiens protein ( Homo sapiens
cDNA FLJ37572 fis, clone BRCOC2002751, weakly similar to
RAS SUPPRESSOR PROTEIN 1. ).
Length = 239
Score = 67.3 bits (157), Expect = 4e-11
Identities = 51/166 (30%), Positives = 85/166 (51%), Gaps = 2/166 (1%)
Frame = -3
Query: 542 HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLR 363
+++ I +SNN +L + L++L L+ + + LP+E + L TLSL N LR
Sbjct: 39 NLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLTVLPDEICNLKKLETLSLNNNHLR 98
Query: 362 ALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRN 183
LP S + L +L+LS N + L P+L LR L+ + N+++ +PDS+ G
Sbjct: 99 ELP-STFGQLSALKTLSLSGNQLGALPPQL-CSLRHLDVMDLSKNQIRSIPDSV--GELQ 154
Query: 182 LTTVSLRNNKISVISMNTFQGATSIRTLDLSYN--RLAFAPDSLYS 51
+ ++L N+IS IS+ ++ L L N L+ P S+ S
Sbjct: 155 VIELNLNQNQISQISVK-ISCCPRLKILRLEENCLELSMLPQSILS 199
Score = 61.3 bits (142), Expect = 3e-09
Identities = 43/134 (32%), Positives = 70/134 (52%), Gaps = 1/134 (0%)
Frame = -3
Query: 455 QLDLSSIRELPEEFIS-NSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAP 279
QL + E P + S LRT+ L+ N++ +LP ++ T L SL+L+ N + L P
Sbjct: 20 QLKDRGLTEFPADLQKLTSNLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLTVL-P 78
Query: 278 ELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTL 99
+ +L+ LET ++ N L+ LP S F L L T+SL N++ + + +
Sbjct: 79 DEICNLKKLETLSLNNNHLRELP-STFGQLSALKTLSLSGNQLGALPPQ-LCSLRHLDVM 136
Query: 98 DLSYNRLAFAPDSL 57
DLS N++ PDS+
Sbjct: 137 DLSKNQIRSIPDSV 150
Score = 36.7 bits (81), Expect = 0.063
Identities = 25/78 (32%), Positives = 37/78 (47%)
Frame = -3
Query: 245 FVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAP 66
F + L P L NL T+ L NNKI + T +++L L+ N+L P
Sbjct: 19 FQLKDRGLTEFPADLQKLTSNLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLTVLP 78
Query: 65 DSLYSPLNQLHKLQTLTL 12
D + + L KL+TL+L
Sbjct: 79 DEICN----LKKLETLSL 92
>AK094131-1|BAC04294.1| 239|Homo sapiens (EC 2.4.1.101). protein.
Length = 239
Score = 67.3 bits (157), Expect = 4e-11
Identities = 51/166 (30%), Positives = 85/166 (51%), Gaps = 2/166 (1%)
Frame = -3
Query: 542 HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLR 363
+++ I +SNN +L + L++L L+ + + LP+E + L TLSL N LR
Sbjct: 39 NLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLTVLPDEICNLKKLETLSLNNNHLR 98
Query: 362 ALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRN 183
LP S + L +L+LS N + L P+L LR L+ + N+++ +PDS+ G
Sbjct: 99 ELP-STFGQLSALKTLSLSGNQLGALPPQL-CSLRHLDVMDLSKNQIRSIPDSV--GELQ 154
Query: 182 LTTVSLRNNKISVISMNTFQGATSIRTLDLSYN--RLAFAPDSLYS 51
+ ++L N+IS IS+ ++ L L N L+ P S+ S
Sbjct: 155 VIELNLNQNQISQISVK-ISCCPRLKILRLEENCLELSMLPQSILS 199
Score = 61.3 bits (142), Expect = 3e-09
Identities = 43/134 (32%), Positives = 70/134 (52%), Gaps = 1/134 (0%)
Frame = -3
Query: 455 QLDLSSIRELPEEFIS-NSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAP 279
QL + E P + S LRT+ L+ N++ +LP ++ T L SL+L+ N + L P
Sbjct: 20 QLKDRGLTEFPADLQKLTSNLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLTVL-P 78
Query: 278 ELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTL 99
+ +L+ LET ++ N L+ LP S F L L T+SL N++ + + +
Sbjct: 79 DEICNLKKLETLSLNNNHLRELP-STFGQLSALKTLSLSGNQLGALPPQ-LCSLRHLDVM 136
Query: 98 DLSYNRLAFAPDSL 57
DLS N++ PDS+
Sbjct: 137 DLSKNQIRSIPDSV 150
Score = 36.7 bits (81), Expect = 0.063
Identities = 25/78 (32%), Positives = 37/78 (47%)
Frame = -3
Query: 245 FVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAP 66
F + L P L NL T+ L NNKI + T +++L L+ N+L P
Sbjct: 19 FQLKDRGLTEFPADLQKLTSNLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLTVLP 78
Query: 65 DSLYSPLNQLHKLQTLTL 12
D + + L KL+TL+L
Sbjct: 79 DEICN----LKKLETLSL 92
>D63481-1|BAA09768.3| 1630|Homo sapiens KIAA0147 protein protein.
Length = 1630
Score = 66.5 bits (155), Expect = 7e-11
Identities = 56/180 (31%), Positives = 87/180 (48%)
Frame = -3
Query: 542 HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLR 363
H++ + + + E ++ +L L LD + +RELP+ F LR L L+ N+++
Sbjct: 13 HVESVDKRHCSLQAVPEEIYRYSRSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQ 72
Query: 362 ALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRN 183
LP V QL L +S N + E+ PE +ALE GN L LPD F+ LR+
Sbjct: 73 RLPPEVANFM-QLVELDVSRNDIPEI-PESIKFCKALEIADFSGNPLSRLPDG-FTQLRS 129
Query: 182 LTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
L ++L + + + + A + TL+L N L P S L+ L KL+ L L N
Sbjct: 130 LAHLALNDVSLQALPGDVGNLANLV-TLELRENLLKSLPAS----LSFLVKLEQLDLGGN 184
Score = 52.4 bits (120), Expect = 1e-06
Identities = 51/163 (31%), Positives = 80/163 (49%), Gaps = 7/163 (4%)
Frame = -3
Query: 524 ISNNVPLTLKEAVFSNLPA-----LRTLQLDL--SSIRELPEEFISNSPLRTLSLARNQL 366
++N V L L+E + +LPA ++ QLDL + + LP+ + LR L L RNQL
Sbjct: 150 LANLVTLELRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQL 209
Query: 365 RALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLR 186
ALP L +L L +S N + EL EL L L ++ N L+ LPD + L+
Sbjct: 210 SALPPE-LGNLRRLVCLDVSENRLEELPAEL-GGLVLLTDLLLSQNLLRRLPDGI-GQLK 266
Query: 185 NLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
L+ + + N++ ++ ++ L L+ N L P SL
Sbjct: 267 QLSILKVDQNRLCEVT-EAIGDCENLSELILTENLLMALPRSL 308
>AY062238-1|AAL38976.1| 1630|Homo sapiens scribble protein.
Length = 1630
Score = 66.5 bits (155), Expect = 7e-11
Identities = 56/180 (31%), Positives = 87/180 (48%)
Frame = -3
Query: 542 HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLR 363
H++ + + + E ++ +L L LD + +RELP+ F LR L L+ N+++
Sbjct: 13 HVESVDKRHCSLQAVPEEIYRYSRSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQ 72
Query: 362 ALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRN 183
LP V QL L +S N + E+ PE +ALE GN L LPD F+ LR+
Sbjct: 73 RLPPEVANFM-QLVELDVSRNDIPEI-PESIKFCKALEIADFSGNPLSRLPDG-FTQLRS 129
Query: 182 LTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
L ++L + + + + A + TL+L N L P S L+ L KL+ L L N
Sbjct: 130 LAHLALNDVSLQALPGDVGNLANLV-TLELRENLLKSLPAS----LSFLVKLEQLDLGGN 184
Score = 52.4 bits (120), Expect = 1e-06
Identities = 51/163 (31%), Positives = 80/163 (49%), Gaps = 7/163 (4%)
Frame = -3
Query: 524 ISNNVPLTLKEAVFSNLPA-----LRTLQLDL--SSIRELPEEFISNSPLRTLSLARNQL 366
++N V L L+E + +LPA ++ QLDL + + LP+ + LR L L RNQL
Sbjct: 150 LANLVTLELRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQL 209
Query: 365 RALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLR 186
ALP L +L L +S N + EL EL L L ++ N L+ LPD + L+
Sbjct: 210 SALPPE-LGNLRRLVCLDVSENRLEELPAEL-GGLVLLTDLLLSQNLLRRLPDGI-GQLK 266
Query: 185 NLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
L+ + + N++ ++ ++ L L+ N L P SL
Sbjct: 267 QLSILKVDQNRLCEVT-EAIGDCENLSELILTENLLMALPRSL 308
>AL512424-2|CAI14256.1| 380|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 380
Score = 66.5 bits (155), Expect = 7e-11
Identities = 40/141 (28%), Positives = 69/141 (48%), Gaps = 2/141 (1%)
Frame = -3
Query: 494 EAVFSNLPA-LRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRALPRSVLRGQTQLT 321
+A+ N+P L+L+ ++I + + +F LR L L NQ+ A+ R +L
Sbjct: 53 QAIPKNIPRNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELE 112
Query: 320 SLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVI 141
L LS NA+ + + F L+ +D N++ + + F LR L ++L NN I+ I
Sbjct: 113 RLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTI 172
Query: 140 SMNTFQGATSIRTLDLSYNRL 78
+++F +RT L N L
Sbjct: 173 PVSSFNHMPKLRTFRLHSNHL 193
Score = 61.3 bits (142), Expect = 3e-09
Identities = 31/89 (34%), Positives = 50/89 (56%)
Frame = -3
Query: 389 LSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLP 210
+ L N ++++P +L + LS N +AE+AP+ F LR+L + V+ GN++ LP
Sbjct: 290 IRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLP 349
Query: 209 DSLFSGLRNLTTVSLRNNKISVISMNTFQ 123
+F GL L + L NKI+ I + FQ
Sbjct: 350 RGVFGGLYTLQLLLLNANKINCIRPDAFQ 378
Score = 47.2 bits (107), Expect = 4e-05
Identities = 24/90 (26%), Positives = 45/90 (50%), Gaps = 1/90 (1%)
Frame = -3
Query: 326 LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKIS 147
+T + L N + + P F+ R L + N++ + F GLR+L ++ L NKI+
Sbjct: 287 MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKIT 346
Query: 146 VISMNTFQGATSIRTLDLSYNRL-AFAPDS 60
+ F G +++ L L+ N++ PD+
Sbjct: 347 DLPRGVFGGLYTLQLLLLNANKINCIRPDA 376
Score = 41.9 bits (94), Expect = 0.002
Identities = 22/68 (32%), Positives = 36/68 (52%)
Frame = -3
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N ++ +P FS R L + L NN+I+ I+ + FQG S+ +L L N++ P ++
Sbjct: 295 NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFG 354
Query: 50 PLNQLHKL 27
L L L
Sbjct: 355 GLYTLQLL 362
Score = 40.3 bits (90), Expect = 0.005
Identities = 21/79 (26%), Positives = 34/79 (43%)
Frame = -3
Query: 260 RALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNR 81
R E ++GN + + + F+GL+ L + L N+I + F + LDLS N
Sbjct: 61 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLDLSENA 120
Query: 80 LAFAPDSLYSPLNQLHKLQ 24
+ P + L LQ
Sbjct: 121 IQAIPRKAFRGATDLKNLQ 139
Score = 31.1 bits (67), Expect = 3.1
Identities = 44/202 (21%), Positives = 83/202 (41%), Gaps = 14/202 (6%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI-----REL 426
+N ++ FR L ++ + ++NN T+ + F+++P LRT +L + +
Sbjct: 142 KNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAW 201
Query: 425 PEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFAD------ 264
+++ P L + +L R + + Q + + S A P
Sbjct: 202 LSQWLRQRPTIGLFTQCSGPASL-RGLNVAEVQKSEFSCSGQGEAGRVPTCTLSSGSCPA 260
Query: 263 LRALETFVMD--GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLS 90
+ ++D G L +P +L +T + L N I I F +R +DLS
Sbjct: 261 MCTCSNGIVDCRGKGLTAIPANL---PETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLS 317
Query: 89 YNRLA-FAPDSLYSPLNQLHKL 27
N++A APD+ + L L+ L
Sbjct: 318 NNQIAEIAPDA-FQGLRSLNSL 338
>AF240677-1|AAP88017.1| 1630|Homo sapiens CRIB1 protein.
Length = 1630
Score = 66.5 bits (155), Expect = 7e-11
Identities = 56/180 (31%), Positives = 87/180 (48%)
Frame = -3
Query: 542 HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLR 363
H++ + + + E ++ +L L LD + +RELP+ F LR L L+ N+++
Sbjct: 13 HVESVDKRHCSLQAVPEEIYRYSRSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQ 72
Query: 362 ALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRN 183
LP V QL L +S N + E+ PE +ALE GN L LPD F+ LR+
Sbjct: 73 RLPPEVANFM-QLVELDVSRNDIPEI-PESIKFCKALEIADFSGNPLSRLPDG-FTQLRS 129
Query: 182 LTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
L ++L + + + + A + TL+L N L P S L+ L KL+ L L N
Sbjct: 130 LAHLALNDVSLQALPGDVGNLANLV-TLELRENLLKSLPAS----LSFLVKLEQLDLGGN 184
Score = 52.4 bits (120), Expect = 1e-06
Identities = 51/163 (31%), Positives = 80/163 (49%), Gaps = 7/163 (4%)
Frame = -3
Query: 524 ISNNVPLTLKEAVFSNLPA-----LRTLQLDL--SSIRELPEEFISNSPLRTLSLARNQL 366
++N V L L+E + +LPA ++ QLDL + + LP+ + LR L L RNQL
Sbjct: 150 LANLVTLELRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQL 209
Query: 365 RALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLR 186
ALP L +L L +S N + EL EL L L ++ N L+ LPD + L+
Sbjct: 210 SALPPE-LGNLRRLVCLDVSENRLEELPAEL-GGLVLLTDLLLSQNLLRRLPDGI-GQLK 266
Query: 185 NLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
L+ + + N++ ++ ++ L L+ N L P SL
Sbjct: 267 QLSILKVDQNRLCEVT-EAIGDCENLSELILTENLLMALPRSL 308
>AB016816-1|BAA74737.1| 1052|Homo sapiens MASL1 protein.
Length = 1052
Score = 66.5 bits (155), Expect = 7e-11
Identities = 58/187 (31%), Positives = 88/187 (47%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N L +E+ L ++++ +S+N L A L L L + + + LP+
Sbjct: 121 NRLTALGAEVVSALRELRKLNLSHN-QLPALPAQLGALAHLEELDVSFNRLAHLPDSLSC 179
Query: 407 NSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 228
S LRTL + NQL A PR +L+ L L +S N + L PE + LRAL+ + G
Sbjct: 180 LSRLRTLDVDHNQLTAFPRQLLQ-LVALEELDVSSNRLRGL-PEDISALRALKILWLSGA 237
Query: 227 ELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSP 48
EL LP F L +L ++ L NN + + F ++ L+LS N P +L P
Sbjct: 238 ELGTLPAG-FCELASLESLMLDNNGLQALPAQ-FSCLQRLKMLNLSSNLFEEFPAALL-P 294
Query: 47 LNQLHKL 27
L L +L
Sbjct: 295 LAGLEEL 301
Score = 60.9 bits (141), Expect = 3e-09
Identities = 43/136 (31%), Positives = 69/136 (50%)
Frame = -3
Query: 557 FRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLA 378
F L ++ + + NN L A FS L L+ L L + E P + + L L L+
Sbjct: 246 FCELASLESLMLDNN-GLQALPAQFSCLQRLKMLNLSSNLFEEFPAALLPLAGLEELYLS 304
Query: 377 RNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLF 198
RNQL ++P S++ G +L +L L N + L P+ +L LE V+ GN++ VLPD F
Sbjct: 305 RNQLTSVP-SLISGLGRLLTLWLDNNRIRYL-PDSIVELTGLEELVLQGNQIAVLPDH-F 361
Query: 197 SGLRNLTTVSLRNNKI 150
L + +++N +
Sbjct: 362 GQLSRVGLWKIKDNPL 377
Score = 60.5 bits (140), Expect = 4e-09
Identities = 43/143 (30%), Positives = 71/143 (49%), Gaps = 1/143 (0%)
Frame = -3
Query: 482 SNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRALPRSVLRGQTQLTSLTLS 306
+NL + L L + + E+PE S LR L L RN+ LP +V LT L +S
Sbjct: 60 ANLGDIEALNLGNNGLEEVPEGLGSALGSLRVLVLRRNRFARLPPAVAELGHHLTELDVS 119
Query: 305 YNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTF 126
+N + L E+ + LR L + N+L LP L L +L + + N+++ + ++
Sbjct: 120 HNRLTALGAEVVSALRELRKLNLSHNQLPALPAQL-GALAHLEELDVSFNRLAHLP-DSL 177
Query: 125 QGATSIRTLDLSYNRLAFAPDSL 57
+ +RTLD+ +N+L P L
Sbjct: 178 SCLSRLRTLDVDHNQLTAFPRQL 200
Score = 56.8 bits (131), Expect = 5e-08
Identities = 54/188 (28%), Positives = 90/188 (47%), Gaps = 24/188 (12%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L H++E+ +S N L +++ S L LRTL +D + + P + + L L ++ N+
Sbjct: 157 LAHLEELDVSFNRLAHLPDSL-SCLSRLRTLDVDHNQLTAFPRQLLQLVALEELDVSSNR 215
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELA--PELFADLRALETFVMDGNELQVLPDSLFS 195
LR LP + + L +L + + + AEL P F +L +LE+ ++D N LQ LP + FS
Sbjct: 216 LRGLPEDI----SALRALKILWLSGAELGTLPAGFCELASLESLMLDNNGLQALP-AQFS 270
Query: 194 GLRNLTTVSLRNNKIS---------------VISMNTFQGATSI-------RTLDLSYNR 81
L+ L ++L +N +S N S+ TL L NR
Sbjct: 271 CLQRLKMLNLSSNLFEEFPAALLPLAGLEELYLSRNQLTSVPSLISGLGRLLTLWLDNNR 330
Query: 80 LAFAPDSL 57
+ + PDS+
Sbjct: 331 IRYLPDSI 338
>AJ297858-1|CAC82651.1| 649|Homo sapiens hypothetical protein
protein.
Length = 649
Score = 66.1 bits (154), Expect = 9e-11
Identities = 54/198 (27%), Positives = 83/198 (41%), Gaps = 2/198 (1%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFI 411
RNS R ++ F GL + +++ +N + F L LR L L + I +P
Sbjct: 108 RNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAF 167
Query: 410 SNSP-LRTLSLAR-NQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVM 237
+ P L L L +L + G L L L + ++ P L L LE M
Sbjct: 168 NRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYLNLGMCNIKDM-PNL-TPLVGLEELEM 225
Query: 236 DGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
GN + F GL +L + + N+ N F G S+ L+L++N L+ P L
Sbjct: 226 SGNHFPEIRPGSFHGLSSLKKLWVMNSH----ERNAFDGLASLVELNLAHNNLSSLPHDL 281
Query: 56 YSPLNQLHKLQTLTLAWN 3
++PL L +L WN
Sbjct: 282 FTPLRYLVELHLHHNPWN 299
Score = 52.8 bits (121), Expect = 9e-07
Identities = 39/138 (28%), Positives = 60/138 (43%), Gaps = 1/138 (0%)
Frame = -3
Query: 437 IRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 258
+ E+P+ SN+ R L+L N ++ + R L L L N++ ++ F L
Sbjct: 66 LSEVPQGIPSNT--RYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLA 123
Query: 257 ALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDL-SYNR 81
+L T + N L V+P F L L + LRNN I I F S+ LDL +
Sbjct: 124 SLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKK 183
Query: 80 LAFAPDSLYSPLNQLHKL 27
L + + + L L L
Sbjct: 184 LEYISEGAFEGLFNLKYL 201
>BC126464-1|AAI26465.1| 1371|Homo sapiens erbb2 interacting protein
protein.
Length = 1371
Score = 65.7 bits (153), Expect = 1e-10
Identities = 60/199 (30%), Positives = 89/199 (44%)
Frame = -3
Query: 602 FTMMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP 423
F M N ++ I L + + +S N ++E + S L+ L L +S+++LP
Sbjct: 212 FWMDANRLTFIPGFI-GSLKQLTYLDVSKNNIEMVEEGI-STCENLQDLLLSSNSLQQLP 269
Query: 422 EEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETF 243
E + TL + NQL LP S+ G + L S+N V E P L L TF
Sbjct: 270 ETIGLLKNITTLKIDENQLMYLPDSI-GGLISVEELDCSFNEV-EALPSSIGQLTNLRTF 327
Query: 242 VMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPD 63
D N LQ LP + S +N+T + L +NK+ + ++ ++LS NRL P
Sbjct: 328 AADHNYLQQLPPEIGS-WKNITVLFLHSNKLETLP-EEMGDMQKLKVINLSDNRLKNLPF 385
Query: 62 SLYSPLNQLHKLQTLTLAW 6
S KLQ LT W
Sbjct: 386 S-------FTKLQQLTAMW 397
Score = 64.1 bits (149), Expect = 4e-10
Identities = 51/162 (31%), Positives = 76/162 (46%)
Frame = -3
Query: 488 VFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTL 309
+F+ L L LD + I ELP++ + L LSL N L LP S+ L L +
Sbjct: 41 IFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASI-ANLINLRELDV 99
Query: 308 SYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNT 129
S N + E PE + + L N + LPD FS L NLT + L + + + N
Sbjct: 100 SKNGIQEF-PENIKNCKVLTIVEASVNPISKLPDG-FSQLLNLTQLYLNDAFLEFLPAN- 156
Query: 128 FQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
F T ++ L+L N+L P + +N+L +L+ L L N
Sbjct: 157 FGRLTKLQILELRENQLKMLPKT----MNRLTQLERLDLGSN 194
Score = 62.1 bits (144), Expect = 1e-09
Identities = 46/143 (32%), Positives = 70/143 (48%)
Frame = -3
Query: 485 FSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLS 306
FS L L L L+ + + LP F + L+ L L NQL+ LP+++ R TQL L L
Sbjct: 134 FSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNR-LTQLERLDLG 192
Query: 305 YNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTF 126
N E+ PE+ L L+ F MD N L +P L+ LT + + N I ++
Sbjct: 193 SNEFTEV-PEVLEQLSGLKEFWMDANRLTFIP-GFIGSLKQLTYLDVSKNNIEMVE-EGI 249
Query: 125 QGATSIRTLDLSYNRLAFAPDSL 57
+++ L LS N L P+++
Sbjct: 250 STCENLQDLLLSSNSLQQLPETI 272
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/105 (26%), Positives = 61/105 (58%), Gaps = 1/105 (0%)
Frame = -3
Query: 368 LRALPRSVLRGQTQ-LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSG 192
+R +P LRG+ + +T+L S+ ++ ++ E+F + LE +D N+++ LP LF+
Sbjct: 9 VRLVPCRCLRGEEETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFN- 67
Query: 191 LRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
++L +SL +N ++ + + ++R LD+S N + P+++
Sbjct: 68 CQSLHKLSLPDNDLTTLPA-SIANLINLRELDVSKNGIQEFPENI 111
>BC113617-1|AAI13618.1| 757|Homo sapiens relaxin/insulin-like
family peptide receptor 1 protein.
Length = 757
Score = 65.3 bits (152), Expect = 2e-10
Identities = 50/189 (26%), Positives = 81/189 (42%), Gaps = 2/189 (1%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFI 411
N R L + F+ +Q++ + NN ++ F L +L L L + I L P F
Sbjct: 136 NLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFE 195
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPE-LFADLRALETFVMD 234
L L + N L + G L L L N + L + L + L ++
Sbjct: 196 DLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLE 255
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
GN + L + F NLT + +R NKI+ ++ NTF + LDL N++ P ++
Sbjct: 256 GNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIF 315
Query: 53 SPLNQLHKL 27
L +L +L
Sbjct: 316 KDLKELSQL 324
Score = 60.1 bits (139), Expect = 6e-09
Identities = 47/173 (27%), Positives = 79/173 (45%), Gaps = 2/173 (1%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PE 420
+ N + FRGL+ + ++ +S+N LK VF +L L L ++ + + + P
Sbjct: 157 LQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPP 216
Query: 419 EFISNSPLRTLSLARNQLRALP-RSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETF 243
F + L L L N L LP + + + +L L L N + L F L
Sbjct: 217 TFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVL 276
Query: 242 VMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
VM N++ L ++ F+ L+ L + L +NKI + F+ + L+LSYN
Sbjct: 277 VMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYN 329
>BC112142-1|AAI12143.1| 757|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 7 protein.
Length = 757
Score = 65.3 bits (152), Expect = 2e-10
Identities = 50/189 (26%), Positives = 81/189 (42%), Gaps = 2/189 (1%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFI 411
N R L + F+ +Q++ + NN ++ F L +L L L + I L P F
Sbjct: 136 NLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFE 195
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPE-LFADLRALETFVMD 234
L L + N L + G L L L N + L + L + L ++
Sbjct: 196 DLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLE 255
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
GN + L + F NLT + +R NKI+ ++ NTF + LDL N++ P ++
Sbjct: 256 GNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIF 315
Query: 53 SPLNQLHKL 27
L +L +L
Sbjct: 316 KDLKELSQL 324
Score = 60.1 bits (139), Expect = 6e-09
Identities = 47/173 (27%), Positives = 79/173 (45%), Gaps = 2/173 (1%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PE 420
+ N + FRGL+ + ++ +S+N LK VF +L L L ++ + + + P
Sbjct: 157 LQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPP 216
Query: 419 EFISNSPLRTLSLARNQLRALP-RSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETF 243
F + L L L N L LP + + + +L L L N + L F L
Sbjct: 217 TFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVL 276
Query: 242 VMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
VM N++ L ++ F+ L+ L + L +NKI + F+ + L+LSYN
Sbjct: 277 VMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYN 329
>AY899850-1|AAX85198.1| 724|Homo sapiens LGR7.10 protein.
Length = 724
Score = 65.3 bits (152), Expect = 2e-10
Identities = 50/189 (26%), Positives = 81/189 (42%), Gaps = 2/189 (1%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFI 411
N R L + F+ +Q++ + NN ++ F L +L L L + I L P F
Sbjct: 103 NLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFE 162
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPE-LFADLRALETFVMD 234
L L + N L + G L L L N + L + L + L ++
Sbjct: 163 DLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLE 222
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
GN + L + F NLT + +R NKI+ ++ NTF + LDL N++ P ++
Sbjct: 223 GNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIF 282
Query: 53 SPLNQLHKL 27
L +L +L
Sbjct: 283 KDLKELSQL 291
Score = 60.1 bits (139), Expect = 6e-09
Identities = 47/173 (27%), Positives = 79/173 (45%), Gaps = 2/173 (1%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PE 420
+ N + FRGL+ + ++ +S+N LK VF +L L L ++ + + + P
Sbjct: 124 LQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPP 183
Query: 419 EFISNSPLRTLSLARNQLRALP-RSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETF 243
F + L L L N L LP + + + +L L L N + L F L
Sbjct: 184 TFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVL 243
Query: 242 VMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
VM N++ L ++ F+ L+ L + L +NKI + F+ + L+LSYN
Sbjct: 244 VMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYN 296
>AF190500-1|AAG17167.1| 757|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 7 protein.
Length = 757
Score = 65.3 bits (152), Expect = 2e-10
Identities = 50/189 (26%), Positives = 81/189 (42%), Gaps = 2/189 (1%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFI 411
N R L + F+ +Q++ + NN ++ F L +L L L + I L P F
Sbjct: 136 NLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFE 195
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPE-LFADLRALETFVMD 234
L L + N L + G L L L N + L + L + L ++
Sbjct: 196 DLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLE 255
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
GN + L + F NLT + +R NKI+ ++ NTF + LDL N++ P ++
Sbjct: 256 GNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIF 315
Query: 53 SPLNQLHKL 27
L +L +L
Sbjct: 316 KDLKELSQL 324
Score = 60.1 bits (139), Expect = 6e-09
Identities = 47/173 (27%), Positives = 79/173 (45%), Gaps = 2/173 (1%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PE 420
+ N + FRGL+ + ++ +S+N LK VF +L L L ++ + + + P
Sbjct: 157 LQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPP 216
Query: 419 EFISNSPLRTLSLARNQLRALP-RSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETF 243
F + L L L N L LP + + + +L L L N + L F L
Sbjct: 217 TFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVL 276
Query: 242 VMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
VM N++ L ++ F+ L+ L + L +NKI + F+ + L+LSYN
Sbjct: 277 VMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYN 329
>BC150568-1|AAI50569.1| 370|Homo sapiens leucine-rich repeats and
transmembrane domains 2 protein.
Length = 370
Score = 64.9 bits (151), Expect = 2e-10
Identities = 44/130 (33%), Positives = 65/130 (50%), Gaps = 1/130 (0%)
Frame = -3
Query: 470 ALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAV 294
A RTL L + + LP +N S L+ L L+ N L LPRS+ T LT L L N++
Sbjct: 69 ATRTLLLLNNKLSALPSWAFANLSSLQRLDLSNNFLDRLPRSIFGDLTNLTELQLRNNSI 128
Query: 293 AELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGAT 114
L +L L + N L LP LF GL L ++SLR+N++ + TF+
Sbjct: 129 RTLDRDLLRHSPLLRHLDLSINGLAQLPPGLFDGLLALRSLSLRSNRLQNLDRLTFEPLA 188
Query: 113 SIRTLDLSYN 84
+++ L + N
Sbjct: 189 NLQLLQVGDN 198
Score = 60.5 bits (140), Expect = 4e-09
Identities = 36/98 (36%), Positives = 51/98 (52%)
Frame = -3
Query: 320 SLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVI 141
+L L N ++ L FA+L +L+ + N L LP S+F L NLT + LRNN I +
Sbjct: 72 TLLLLNNKLSALPSWAFANLSSLQRLDLSNNFLDRLPRSIFGDLTNLTELQLRNNSIRTL 131
Query: 140 SMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+ + + +R LDLS N LA P L+ L L L
Sbjct: 132 DRDLLRHSPLLRHLDLSINGLAQLPPGLFDGLLALRSL 169
Score = 58.8 bits (136), Expect = 1e-08
Identities = 41/124 (33%), Positives = 59/124 (47%), Gaps = 1/124 (0%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
++ N L S F L +Q + +SNN L ++F +L L LQL +SIR L +
Sbjct: 75 LLNNKLSALPSWAFANLSSLQRLDLSNNFLDRLPRSIFGDLTNLTELQLRNNSIRTLDRD 134
Query: 416 FISNSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+ +SP LR L L+ N L LP + G L SL+L N + L F L L+
Sbjct: 135 LLRHSPLLRHLDLSINGLAQLPPGLFDGLLALRSLSLRSNRLQNLDRLTFEPLANLQLLQ 194
Query: 239 MDGN 228
+ N
Sbjct: 195 VGDN 198
Score = 55.6 bits (128), Expect = 1e-07
Identities = 43/153 (28%), Positives = 63/153 (41%)
Frame = -3
Query: 464 RTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAEL 285
R+L++D S + + RTL L N+L ALP + L L LS N + L
Sbjct: 48 RSLEVDCSGLGLTTVPPDVPAATRTLLLLNNKLSALPSWAFANLSSLQRLDLSNNFLDRL 107
Query: 284 APELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIR 105
+F DL L + N ++ L L L + L N ++ + F G ++R
Sbjct: 108 PRSIFGDLTNLTELQLRNNSIRTLDRDLLRHSPLLRHLDLSINGLAQLPPGLFDGLLALR 167
Query: 104 TLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAW 6
+L L NRL + PL L LQ W
Sbjct: 168 SLSLRSNRLQNLDRLTFEPLANLQLLQVGDNPW 200
>AK095610-1|BAC04589.1| 370|Homo sapiens protein ( Homo sapiens
cDNA FLJ38291 fis, clone FCBBF3009069, weakly similar to
Homo sapiens HT017 mRNA. ).
Length = 370
Score = 64.9 bits (151), Expect = 2e-10
Identities = 44/130 (33%), Positives = 65/130 (50%), Gaps = 1/130 (0%)
Frame = -3
Query: 470 ALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAV 294
A RTL L + + LP +N S L+ L L+ N L LPRS+ T LT L L N++
Sbjct: 69 ATRTLLLLNNKLSALPSWAFANLSSLQRLDLSNNFLDRLPRSIFGDLTNLTELQLRNNSI 128
Query: 293 AELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGAT 114
L +L L + N L LP LF GL L ++SLR+N++ + TF+
Sbjct: 129 RTLDRDLLRHSPLLRHLDLSINGLAQLPPGLFDGLLALRSLSLRSNRLQNLDRLTFEPLA 188
Query: 113 SIRTLDLSYN 84
+++ L + N
Sbjct: 189 NLQLLQVGDN 198
Score = 60.5 bits (140), Expect = 4e-09
Identities = 36/98 (36%), Positives = 51/98 (52%)
Frame = -3
Query: 320 SLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVI 141
+L L N ++ L FA+L +L+ + N L LP S+F L NLT + LRNN I +
Sbjct: 72 TLLLLNNKLSALPSWAFANLSSLQRLDLSNNFLDRLPRSIFGDLTNLTELQLRNNSIRTL 131
Query: 140 SMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
+ + + +R LDLS N LA P L+ L L L
Sbjct: 132 DRDLLRHSPLLRHLDLSINGLAQLPPGLFDGLLALRSL 169
Score = 58.8 bits (136), Expect = 1e-08
Identities = 41/124 (33%), Positives = 59/124 (47%), Gaps = 1/124 (0%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
++ N L S F L +Q + +SNN L ++F +L L LQL +SIR L +
Sbjct: 75 LLNNKLSALPSWAFANLSSLQRLDLSNNFLDRLPRSIFGDLTNLTELQLRNNSIRTLDRD 134
Query: 416 FISNSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+ +SP LR L L+ N L LP + G L SL+L N + L F L L+
Sbjct: 135 LLRHSPLLRHLDLSINGLAQLPPGLFDGLLALRSLSLRSNRLQNLDRLTFEPLANLQLLQ 194
Query: 239 MDGN 228
+ N
Sbjct: 195 VGDN 198
Score = 55.6 bits (128), Expect = 1e-07
Identities = 43/153 (28%), Positives = 63/153 (41%)
Frame = -3
Query: 464 RTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAEL 285
R+L++D S + + RTL L N+L ALP + L L LS N + L
Sbjct: 48 RSLEVDCSGLGLTTVPPDVPAATRTLLLLNNKLSALPSWAFANLSSLQRLDLSNNFLDRL 107
Query: 284 APELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIR 105
+F DL L + N ++ L L L + L N ++ + F G ++R
Sbjct: 108 PRSIFGDLTNLTELQLRNNSIRTLDRDLLRHSPLLRHLDLSINGLAQLPPGLFDGLLALR 167
Query: 104 TLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAW 6
+L L NRL + PL L LQ W
Sbjct: 168 SLSLRSNRLQNLDRLTFEPLANLQLLQVGDNPW 200
>BC035281-1|AAH35281.1| 376|Homo sapiens fibromodulin protein.
Length = 376
Score = 64.5 bits (150), Expect = 3e-10
Identities = 53/169 (31%), Positives = 85/169 (50%), Gaps = 3/169 (1%)
Frame = -3
Query: 563 EIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTL 387
++F L H++ + + +N LT +LR L LD + I +P + L L
Sbjct: 149 KVFSKLRHLERLYLDHN-NLTRMPGPLPR--SLRELHLDHNQISRVPNNALEGLENLTAL 205
Query: 386 SLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPD 207
L N+++ + S +RG L L LSYN + ++ L + ALE M+ N + +PD
Sbjct: 206 YLQHNEIQEVGSS-MRGLRSLILLDLSYNHLRKVPDGLPS---ALEQLYMEHNNVYTVPD 261
Query: 206 SLFSGLRNLTTVSLRNNKI--SVISMNTFQGATSIRTLDLSYNRLAFAP 66
S F G L V L +N + + ++ NTF ++S+ LDLSYN+L P
Sbjct: 262 SYFRGAPKLLYVRLSHNSLTNNGLASNTF-NSSSLLELDLSYNQLQKIP 309
Score = 60.9 bits (141), Expect = 3e-09
Identities = 44/140 (31%), Positives = 71/140 (50%), Gaps = 3/140 (2%)
Frame = -3
Query: 443 SSIRELPEEFISNSP-LRTLSLARNQLRA--LPRSVLRGQTQLTSLTLSYNAVAELAPEL 273
+ I + E N+ L ++L NQ+ + + R V L L L +N + + L
Sbjct: 115 NQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPL 174
Query: 272 FADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDL 93
LR L +D N++ +P++ GL NLT + L++N+I + ++ +G S+ LDL
Sbjct: 175 PRSLRELH---LDHNQISRVPNNALEGLENLTALYLQHNEIQEVG-SSMRGLRSLILLDL 230
Query: 92 SYNRLAFAPDSLYSPLNQLH 33
SYN L PD L S L QL+
Sbjct: 231 SYNHLRKVPDGLPSALEQLY 250
>BC008586-1|AAH08586.1| 602|Homo sapiens leucine rich repeat
containing 40 protein.
Length = 602
Score = 64.5 bits (150), Expect = 3e-10
Identities = 50/177 (28%), Positives = 85/177 (48%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N + L EI L +++ + + +N + E F L L L L + + +P F S
Sbjct: 138 NKLKILPEEI-TNLRNLKCLYLQHNELTCISEG-FEQLSNLEDLDLSNNHLTTVPASFSS 195
Query: 407 NSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 228
S L L+L+ N+L++LP + R +L L + N + + PEL A + +LE + N
Sbjct: 196 LSSLVRLNLSSNELKSLPAEINR-MKRLKHLDCNSNLLETIPPEL-AGMESLELLYLRRN 253
Query: 227 ELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
+L+ LP+ F L + + N+I ++ + SI LDL N+L PD +
Sbjct: 254 KLRFLPE--FPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEI 308
Score = 49.2 bits (112), Expect = 1e-05
Identities = 49/186 (26%), Positives = 84/186 (45%), Gaps = 1/186 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N + L ++ R L + + I +N +L A+ L L+ L + + ++ LPEE +
Sbjct: 92 NKLQSLTDDL-RLLPALTVLDIHDNQLTSLPSAI-RELENLQKLNVSHNKLKILPEEITN 149
Query: 407 NSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 228
L+ L L N+L + + L L LS N + + P F+ L +L + N
Sbjct: 150 LRNLKCLYLQHNELTCISEG-FEQLSNLEDLDLSNNHLTTV-PASFSSLSSLVRLNLSSN 207
Query: 227 ELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPD-SLYS 51
EL+ LP + + ++ L + +N + I G S+ L L N+L F P+ S
Sbjct: 208 ELKSLPAEI-NRMKRLKHLDCNSNLLETIPPE-LAGMESLELLYLRRNKLRFLPEFPSCS 265
Query: 50 PLNQLH 33
L +LH
Sbjct: 266 LLKELH 271
Score = 46.4 bits (105), Expect = 8e-05
Identities = 31/111 (27%), Positives = 56/111 (50%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L + + + NN +L E + S L L+T+ L + + LPE L T+ ++ NQ
Sbjct: 471 LQKLTFLDLRNNFLNSLPEEMES-LVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQ 529
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 216
+ ++ ++ LT+L L N + ++ PEL + L T ++DGN +V
Sbjct: 530 VGSVDPQKMKMMENLTTLDLQNNDLLQIPPEL-GNCVNLRTLLLDGNPFRV 579
Score = 45.6 bits (103), Expect = 1e-04
Identities = 44/171 (25%), Positives = 82/171 (47%), Gaps = 1/171 (0%)
Frame = -3
Query: 512 VPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS-NSPLRTLSLARNQLRALPRSVLRG 336
+P + +AV SN+ + ++ + + E+P+ + + + L+ N+L + +
Sbjct: 414 IPDEVFDAVKSNI--VTSINFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVL 471
Query: 335 QTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNN 156
Q +LT L L N + L PE L L+T + N ++LP+ L+ + L T+ + NN
Sbjct: 472 Q-KLTFLDLRNNFLNSL-PEEMESLVRLQTINLSFNRFKMLPEVLYR-IFTLETILISNN 528
Query: 155 KISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
++ + + ++ TLDL N L P L + +N L+TL L N
Sbjct: 529 QVGSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVN----LRTLLLDGN 575
Score = 44.0 bits (99), Expect = 4e-04
Identities = 35/152 (23%), Positives = 65/152 (42%)
Frame = -3
Query: 539 IQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRA 360
+ I S N + + + + + L + + + E L L L N L +
Sbjct: 427 VTSINFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNS 486
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
LP + +L ++ LS+N ++ PE+ + LET ++ N++ + + NL
Sbjct: 487 LPEE-MESLVRLQTINLSFNRF-KMLPEVLYRIFTLETILISNNQVGSVDPQKMKMMENL 544
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
TT+ L+NN + I ++RTL L N
Sbjct: 545 TTLDLQNNDLLQIPPE-LGNCVNLRTLLLDGN 575
Score = 38.3 bits (85), Expect = 0.021
Identities = 27/110 (24%), Positives = 50/110 (45%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ RN R+L F ++E+ + N L+ +L ++ L L + ++ +P+E
Sbjct: 250 LRRNKLRFLPE--FPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDE 307
Query: 416 FISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFA 267
I L L L+ N + +LP S+ G L L L N + + E+ +
Sbjct: 308 IILLRSLERLDLSNNDISSLPYSL--GNLHLKFLALEGNPLRTIRREIIS 355
>BC003407-1|AAH03407.2| 581|Homo sapiens LRRC40 protein protein.
Length = 581
Score = 64.5 bits (150), Expect = 3e-10
Identities = 50/177 (28%), Positives = 85/177 (48%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N + L EI L +++ + + +N + E F L L L L + + +P F S
Sbjct: 117 NKLKILPEEI-TNLRNLKCLYLQHNELTCISEG-FEQLSNLEDLDLSNNHLTTVPASFSS 174
Query: 407 NSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 228
S L L+L+ N+L++LP + R +L L + N + + PEL A + +LE + N
Sbjct: 175 LSSLVRLNLSSNELKSLPAEINR-MKRLKHLDCNSNLLETIPPEL-AGMESLELLYLRRN 232
Query: 227 ELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
+L+ LP+ F L + + N+I ++ + SI LDL N+L PD +
Sbjct: 233 KLRFLPE--FPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEI 287
Score = 49.2 bits (112), Expect = 1e-05
Identities = 49/186 (26%), Positives = 84/186 (45%), Gaps = 1/186 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N + L ++ R L + + I +N +L A+ L L+ L + + ++ LPEE +
Sbjct: 71 NKLQSLTDDL-RLLPALTVLDIHDNQLTSLPSAI-RELENLQKLNVSHNKLKILPEEITN 128
Query: 407 NSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 228
L+ L L N+L + + L L LS N + + P F+ L +L + N
Sbjct: 129 LRNLKCLYLQHNELTCISEG-FEQLSNLEDLDLSNNHLTTV-PASFSSLSSLVRLNLSSN 186
Query: 227 ELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPD-SLYS 51
EL+ LP + + ++ L + +N + I G S+ L L N+L F P+ S
Sbjct: 187 ELKSLPAEI-NRMKRLKHLDCNSNLLETIPPE-LAGMESLELLYLRRNKLRFLPEFPSCS 244
Query: 50 PLNQLH 33
L +LH
Sbjct: 245 LLKELH 250
Score = 46.4 bits (105), Expect = 8e-05
Identities = 31/111 (27%), Positives = 56/111 (50%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L + + + NN +L E + S L L+T+ L + + LPE L T+ ++ NQ
Sbjct: 450 LQKLTFLDLRNNFLNSLPEEMES-LVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQ 508
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 216
+ ++ ++ LT+L L N + ++ PEL + L T ++DGN +V
Sbjct: 509 VGSVDPQKMKMMENLTTLDLQNNDLLQIPPEL-GNCVNLRTLLLDGNPFRV 558
Score = 45.6 bits (103), Expect = 1e-04
Identities = 44/171 (25%), Positives = 82/171 (47%), Gaps = 1/171 (0%)
Frame = -3
Query: 512 VPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS-NSPLRTLSLARNQLRALPRSVLRG 336
+P + +AV SN+ + ++ + + E+P+ + + + L+ N+L + +
Sbjct: 393 IPDEVFDAVKSNI--VTSINFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVL 450
Query: 335 QTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNN 156
Q +LT L L N + L PE L L+T + N ++LP+ L+ + L T+ + NN
Sbjct: 451 Q-KLTFLDLRNNFLNSL-PEEMESLVRLQTINLSFNRFKMLPEVLYR-IFTLETILISNN 507
Query: 155 KISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
++ + + ++ TLDL N L P L + +N L+TL L N
Sbjct: 508 QVGSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVN----LRTLLLDGN 554
Score = 44.0 bits (99), Expect = 4e-04
Identities = 35/152 (23%), Positives = 65/152 (42%)
Frame = -3
Query: 539 IQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRA 360
+ I S N + + + + + L + + + E L L L N L +
Sbjct: 406 VTSINFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNS 465
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
LP + +L ++ LS+N ++ PE+ + LET ++ N++ + + NL
Sbjct: 466 LPEE-MESLVRLQTINLSFNRF-KMLPEVLYRIFTLETILISNNQVGSVDPQKMKMMENL 523
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
TT+ L+NN + I ++RTL L N
Sbjct: 524 TTLDLQNNDLLQIPPE-LGNCVNLRTLLLDGN 554
Score = 38.3 bits (85), Expect = 0.021
Identities = 27/110 (24%), Positives = 50/110 (45%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ RN R+L F ++E+ + N L+ +L ++ L L + ++ +P+E
Sbjct: 229 LRRNKLRFLPE--FPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDE 286
Query: 416 FISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFA 267
I L L L+ N + +LP S+ G L L L N + + E+ +
Sbjct: 287 IILLRSLERLDLSNNDISSLPYSL--GNLHLKFLALEGNPLRTIRREIIS 334
>AL359837-1|CAH73821.1| 376|Homo sapiens fibromodulin protein.
Length = 376
Score = 64.5 bits (150), Expect = 3e-10
Identities = 53/169 (31%), Positives = 85/169 (50%), Gaps = 3/169 (1%)
Frame = -3
Query: 563 EIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTL 387
++F L H++ + + +N LT +LR L LD + I +P + L L
Sbjct: 149 KVFSKLRHLERLYLDHN-NLTRMPGPLPR--SLRELHLDHNQISRVPNNALEGLENLTAL 205
Query: 386 SLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPD 207
L N+++ + S +RG L L LSYN + ++ L + ALE M+ N + +PD
Sbjct: 206 YLQHNEIQEVGSS-MRGLRSLILLDLSYNHLRKVPDGLPS---ALEQLYMEHNNVYTVPD 261
Query: 206 SLFSGLRNLTTVSLRNNKI--SVISMNTFQGATSIRTLDLSYNRLAFAP 66
S F G L V L +N + + ++ NTF ++S+ LDLSYN+L P
Sbjct: 262 SYFRGAPKLLYVRLSHNSLTNNGLASNTF-NSSSLLELDLSYNQLQKIP 309
Score = 60.9 bits (141), Expect = 3e-09
Identities = 44/140 (31%), Positives = 71/140 (50%), Gaps = 3/140 (2%)
Frame = -3
Query: 443 SSIRELPEEFISNSP-LRTLSLARNQLRA--LPRSVLRGQTQLTSLTLSYNAVAELAPEL 273
+ I + E N+ L ++L NQ+ + + R V L L L +N + + L
Sbjct: 115 NQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPL 174
Query: 272 FADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDL 93
LR L +D N++ +P++ GL NLT + L++N+I + ++ +G S+ LDL
Sbjct: 175 PRSLRELH---LDHNQISRVPNNALEGLENLTALYLQHNEIQEVG-SSMRGLRSLILLDL 230
Query: 92 SYNRLAFAPDSLYSPLNQLH 33
SYN L PD L S L QL+
Sbjct: 231 SYNHLRKVPDGLPSALEQLY 250
>AL353771-3|CAI22332.1| 602|Homo sapiens leucine rich repeat
containing 40 protein.
Length = 602
Score = 64.5 bits (150), Expect = 3e-10
Identities = 50/177 (28%), Positives = 85/177 (48%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N + L EI L +++ + + +N + E F L L L L + + +P F S
Sbjct: 138 NKLKILPEEI-TNLRNLKCLYLQHNELTCISEG-FEQLSNLEDLDLSNNHLTTVPASFSS 195
Query: 407 NSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 228
S L L+L+ N+L++LP + R +L L + N + + PEL A + +LE + N
Sbjct: 196 LSSLVRLNLSSNELKSLPAEINR-MKRLKHLDCNSNLLETIPPEL-AGMESLELLYLRRN 253
Query: 227 ELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
+L+ LP+ F L + + N+I ++ + SI LDL N+L PD +
Sbjct: 254 KLRFLPE--FPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEI 308
Score = 49.2 bits (112), Expect = 1e-05
Identities = 49/186 (26%), Positives = 84/186 (45%), Gaps = 1/186 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N + L ++ R L + + I +N +L A+ L L+ L + + ++ LPEE +
Sbjct: 92 NKLQSLTDDL-RLLPALTVLDIHDNQLTSLPSAI-RELENLQKLNVSHNKLKILPEEITN 149
Query: 407 NSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 228
L+ L L N+L + + L L LS N + + P F+ L +L + N
Sbjct: 150 LRNLKCLYLQHNELTCISEG-FEQLSNLEDLDLSNNHLTTV-PASFSSLSSLVRLNLSSN 207
Query: 227 ELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPD-SLYS 51
EL+ LP + + ++ L + +N + I G S+ L L N+L F P+ S
Sbjct: 208 ELKSLPAEI-NRMKRLKHLDCNSNLLETIPPE-LAGMESLELLYLRRNKLRFLPEFPSCS 265
Query: 50 PLNQLH 33
L +LH
Sbjct: 266 LLKELH 271
Score = 46.4 bits (105), Expect = 8e-05
Identities = 31/111 (27%), Positives = 56/111 (50%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L + + + NN +L E + S L L+T+ L + + LPE L T+ ++ NQ
Sbjct: 471 LQKLTFLDLRNNFLNSLPEEMES-LVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQ 529
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 216
+ ++ ++ LT+L L N + ++ PEL + L T ++DGN +V
Sbjct: 530 VGSVDPQKMKMMENLTTLDLQNNDLLQIPPEL-GNCVNLRTLLLDGNPFRV 579
Score = 45.6 bits (103), Expect = 1e-04
Identities = 44/171 (25%), Positives = 82/171 (47%), Gaps = 1/171 (0%)
Frame = -3
Query: 512 VPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS-NSPLRTLSLARNQLRALPRSVLRG 336
+P + +AV SN+ + ++ + + E+P+ + + + L+ N+L + +
Sbjct: 414 IPDEVFDAVKSNI--VTSINFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVL 471
Query: 335 QTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNN 156
Q +LT L L N + L PE L L+T + N ++LP+ L+ + L T+ + NN
Sbjct: 472 Q-KLTFLDLRNNFLNSL-PEEMESLVRLQTINLSFNRFKMLPEVLYR-IFTLETILISNN 528
Query: 155 KISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
++ + + ++ TLDL N L P L + +N L+TL L N
Sbjct: 529 QVGSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVN----LRTLLLDGN 575
Score = 44.0 bits (99), Expect = 4e-04
Identities = 35/152 (23%), Positives = 65/152 (42%)
Frame = -3
Query: 539 IQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRA 360
+ I S N + + + + + L + + + E L L L N L +
Sbjct: 427 VTSINFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNS 486
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
LP + +L ++ LS+N ++ PE+ + LET ++ N++ + + NL
Sbjct: 487 LPEE-MESLVRLQTINLSFNRF-KMLPEVLYRIFTLETILISNNQVGSVDPQKMKMMENL 544
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
TT+ L+NN + I ++RTL L N
Sbjct: 545 TTLDLQNNDLLQIPPE-LGNCVNLRTLLLDGN 575
Score = 38.3 bits (85), Expect = 0.021
Identities = 27/110 (24%), Positives = 50/110 (45%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ RN R+L F ++E+ + N L+ +L ++ L L + ++ +P+E
Sbjct: 250 LRRNKLRFLPE--FPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDE 307
Query: 416 FISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFA 267
I L L L+ N + +LP S+ G L L L N + + E+ +
Sbjct: 308 IILLRSLERLDLSNNDISSLPYSL--GNLHLKFLALEGNPLRTIRREIIS 355
>AK022951-1|BAB14326.1| 602|Homo sapiens protein ( Homo sapiens
cDNA FLJ12889 fis, clone NT2RP2004098, weakly similar to
ADENYLATE CYCLASE (EC 4.6.1.1). ).
Length = 602
Score = 64.5 bits (150), Expect = 3e-10
Identities = 50/177 (28%), Positives = 85/177 (48%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N + L EI L +++ + + +N + E F L L L L + + +P F S
Sbjct: 138 NKLKILPEEI-TNLRNLKCLYLQHNELTCISEG-FEQLSNLEDLDLSNNHLTTVPASFSS 195
Query: 407 NSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 228
S L L+L+ N+L++LP + R +L L + N + + PEL A + +LE + N
Sbjct: 196 LSSLVRLNLSSNELKSLPAEINR-MKRLKHLDCNSNLLETIPPEL-AGMESLELLYLRRN 253
Query: 227 ELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
+L+ LP+ F L + + N+I ++ + SI LDL N+L PD +
Sbjct: 254 KLRFLPE--FPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEI 308
Score = 49.2 bits (112), Expect = 1e-05
Identities = 49/186 (26%), Positives = 84/186 (45%), Gaps = 1/186 (0%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS 408
N + L ++ R L + + I +N +L A+ L L+ L + + ++ LPEE +
Sbjct: 92 NKLQSLTDDL-RLLPALTVLDIHDNQLTSLPSAI-RELENLQKLNVSHNKLKILPEEITN 149
Query: 407 NSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 228
L+ L L N+L + + L L LS N + + P F+ L +L + N
Sbjct: 150 LRNLKCLYLQHNELTCISEG-FEQLSNLEDLDLSNNHLTTV-PASFSSLSSLVRLNLSSN 207
Query: 227 ELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPD-SLYS 51
EL+ LP + + ++ L + +N + I G S+ L L N+L F P+ S
Sbjct: 208 ELKSLPAEI-NRMKRLKHLDCNSNLLETIPPE-LAGMESLELLYLRRNKLRFLPEFPSCS 265
Query: 50 PLNQLH 33
L +LH
Sbjct: 266 LLKELH 271
Score = 46.4 bits (105), Expect = 8e-05
Identities = 31/111 (27%), Positives = 56/111 (50%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L + + + NN +L E + S L L+T+ L + + LPE L T+ ++ NQ
Sbjct: 471 LQKLTFLDLRNNFLNSLPEEMES-LVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQ 529
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 216
+ ++ ++ LT+L L N + ++ PEL + L T ++DGN +V
Sbjct: 530 VGSVDPQKMKMMENLTTLDLQNNDLLQIPPEL-GNCVNLRTLLLDGNPFRV 579
Score = 45.6 bits (103), Expect = 1e-04
Identities = 44/171 (25%), Positives = 82/171 (47%), Gaps = 1/171 (0%)
Frame = -3
Query: 512 VPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS-NSPLRTLSLARNQLRALPRSVLRG 336
+P + +AV SN+ + ++ + + E+P+ + + + L+ N+L + +
Sbjct: 414 IPDEVFDAVKSNI--VTSINFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVL 471
Query: 335 QTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNN 156
Q +LT L L N + L PE L L+T + N ++LP+ L+ + L T+ + NN
Sbjct: 472 Q-KLTFLDLRNNFLNSL-PEEMESLVRLQTINLSFNRFKMLPEVLYR-IFTLETILISNN 528
Query: 155 KISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
++ + + ++ TLDL N L P L + +N L+TL L N
Sbjct: 529 QVGSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVN----LRTLLLDGN 575
Score = 44.0 bits (99), Expect = 4e-04
Identities = 35/152 (23%), Positives = 65/152 (42%)
Frame = -3
Query: 539 IQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRA 360
+ I S N + + + + + L + + + E L L L N L +
Sbjct: 427 VTSINFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNS 486
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
LP + +L ++ LS+N ++ PE+ + LET ++ N++ + + NL
Sbjct: 487 LPEE-MESLVRLQTINLSFNRF-KMLPEVLYRIFTLETILISNNQVGSVDPQKMKMMENL 544
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYN 84
TT+ L+NN + I ++RTL L N
Sbjct: 545 TTLDLQNNDLLQIPPE-LGNCVNLRTLLLDGN 575
Score = 38.3 bits (85), Expect = 0.021
Identities = 27/110 (24%), Positives = 50/110 (45%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ RN R+L F ++E+ + N L+ +L ++ L L + ++ +P+E
Sbjct: 250 LRRNKLRFLPE--FPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDE 307
Query: 416 FISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFA 267
I L L L+ N + +LP S+ G L L L N + + E+ +
Sbjct: 308 IILLRSLERLDLSNNDISSLPYSL--GNLHLKFLALEGNPLRTIRREIIS 355
>X72913-1|CAA51418.1| 376|Homo sapiens fibromodulin protein.
Length = 376
Score = 64.1 bits (149), Expect = 4e-10
Identities = 53/169 (31%), Positives = 85/169 (50%), Gaps = 3/169 (1%)
Frame = -3
Query: 563 EIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTL 387
++F L H++ + + +N LT +LR L LD + I +P + L L
Sbjct: 149 KVFSKLRHLERLYLDHN-NLTRMPGPLPR--SLRELHLDHNQISRVPNNALEGLENLTAL 205
Query: 386 SLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPD 207
L N+++ + S +RG L L LSYN + ++ L + ALE M+ N + +PD
Sbjct: 206 YLQHNEIQEVGSS-MRGLRSLYLLDLSYNHLRKVPDGLPS---ALEQLYMEHNNVYTVPD 261
Query: 206 SLFSGLRNLTTVSLRNNKI--SVISMNTFQGATSIRTLDLSYNRLAFAP 66
S F G L V L +N + + ++ NTF ++S+ LDLSYN+L P
Sbjct: 262 SYFRGAPKLLYVRLSHNSLTNNGLASNTF-NSSSLLELDLSYNQLQKIP 309
Score = 61.3 bits (142), Expect = 3e-09
Identities = 44/140 (31%), Positives = 71/140 (50%), Gaps = 3/140 (2%)
Frame = -3
Query: 443 SSIRELPEEFISNSP-LRTLSLARNQLRA--LPRSVLRGQTQLTSLTLSYNAVAELAPEL 273
+ I + E N+ L ++L NQ+ + + R V L L L +N + + L
Sbjct: 115 NQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPL 174
Query: 272 FADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDL 93
LR L +D N++ +P++ GL NLT + L++N+I + ++ +G S+ LDL
Sbjct: 175 PRSLRELH---LDHNQISRVPNNALEGLENLTALYLQHNEIQEVG-SSMRGLRSLYLLDL 230
Query: 92 SYNRLAFAPDSLYSPLNQLH 33
SYN L PD L S L QL+
Sbjct: 231 SYNHLRKVPDGLPSALEQLY 250
>AY358114-1|AAQ88481.1| 606|Homo sapiens Tango hlg protein.
Length = 606
Score = 64.1 bits (149), Expect = 4e-10
Identities = 35/123 (28%), Positives = 66/123 (53%)
Frame = -3
Query: 395 RTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 216
+ L L++N+L+++ L + LS N +A + P F +L L + + GN L++
Sbjct: 60 KILDLSKNRLKSVNPEEFISYPLLEEIDLSDNIIANVEPGAFNNLFNLRSLRLKGNRLKL 119
Query: 215 LPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQL 36
+P +F+GL NLT + + NKI ++ FQ ++++L++ N L + +S L L
Sbjct: 120 VPLGVFTGLSNLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGLLSL 179
Query: 35 HKL 27
+L
Sbjct: 180 EQL 182
Score = 64.1 bits (149), Expect = 4e-10
Identities = 41/157 (26%), Positives = 76/157 (48%), Gaps = 1/157 (0%)
Frame = -3
Query: 542 HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQL 366
H++ + I NN+P+ F L L+ L++D + ++ P + L +LS+ L
Sbjct: 207 HLKHLNI-NNMPVY----AFKRLFHLKHLEIDYWPLLDMMPANSLYGLNLTSLSVTNTNL 261
Query: 365 RALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLR 186
+P + LT L LSYN ++ + +F+DL L+ + G +L+ + F GLR
Sbjct: 262 STVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLR 321
Query: 185 NLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLA 75
L +++ N + + N F ++ L ++ N LA
Sbjct: 322 FLRVLNVSQNLLETLEENVFSSPRALEVLSINNNPLA 358
Score = 59.7 bits (138), Expect = 8e-09
Identities = 43/170 (25%), Positives = 77/170 (45%), Gaps = 1/170 (0%)
Frame = -3
Query: 530 IKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRALP 354
+ +S N ++ F + P L + L + I + P F + LR+L L N+L+ +P
Sbjct: 62 LDLSKNRLKSVNPEEFISYPLLEEIDLSDNIIANVEPGAFNNLFNLRSLRLKGNRLKLVP 121
Query: 353 RSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTT 174
V G + LT L +S N + L +F DL L++ + N+L + FSGL +L
Sbjct: 122 LGVFTGLSNLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGLLSLEQ 181
Query: 173 VSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
++L ++ + S+ +L L + + P + L L L+
Sbjct: 182 LTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLE 231
Score = 42.7 bits (96), Expect = 0.001
Identities = 46/190 (24%), Positives = 86/190 (45%), Gaps = 3/190 (1%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISN-NVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EF 414
N Y+ F GL ++++ + N+ EA+ S+L +L +L L +I +P F
Sbjct: 163 NDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEAL-SHLRSLISLHLKHLNINNMPVYAF 221
Query: 413 ISNSPLRTLSLAR-NQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVM 237
L+ L + L +P + L G LTSL+++ ++ + F L L +
Sbjct: 222 KRLFHLKHLEIDYWPLLDMMPANSLYG-LNLTSLSVTNTNLSTVPFLAFKHLVYLTHLNL 280
Query: 236 DGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
N + + +FS L L + + ++ I ++FQG +R L++S N L +++
Sbjct: 281 SYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLRFLRVLNVSQNLLETLEENV 340
Query: 56 YSPLNQLHKL 27
+S L L
Sbjct: 341 FSSPRALEVL 350
Score = 31.1 bits (67), Expect = 3.1
Identities = 15/44 (34%), Positives = 27/44 (61%)
Frame = -3
Query: 578 RYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLD 447
R ++ F+GL ++ + +S N+ TL+E VFS+ AL L ++
Sbjct: 310 RTIEPHSFQGLRFLRVLNVSQNLLETLEENVFSSPRALEVLSIN 353
>AL353746-1|CAC22713.1| 606|Homo sapiens leucine rich repeat and Ig
domain containing 2 protein.
Length = 606
Score = 64.1 bits (149), Expect = 4e-10
Identities = 35/123 (28%), Positives = 66/123 (53%)
Frame = -3
Query: 395 RTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 216
+ L L++N+L+++ L + LS N +A + P F +L L + + GN L++
Sbjct: 60 KILDLSKNRLKSVNPEEFISYPLLEEIDLSDNIIANVEPGAFNNLFNLRSLRLKGNRLKL 119
Query: 215 LPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQL 36
+P +F+GL NLT + + NKI ++ FQ ++++L++ N L + +S L L
Sbjct: 120 VPLGVFTGLSNLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGLLSL 179
Query: 35 HKL 27
+L
Sbjct: 180 EQL 182
Score = 64.1 bits (149), Expect = 4e-10
Identities = 41/157 (26%), Positives = 76/157 (48%), Gaps = 1/157 (0%)
Frame = -3
Query: 542 HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQL 366
H++ + I NN+P+ F L L+ L++D + ++ P + L +LS+ L
Sbjct: 207 HLKHLNI-NNMPVY----AFKRLFHLKHLEIDYWPLLDMMPANSLYGLNLTSLSVTNTNL 261
Query: 365 RALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLR 186
+P + LT L LSYN ++ + +F+DL L+ + G +L+ + F GLR
Sbjct: 262 STVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLR 321
Query: 185 NLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLA 75
L +++ N + + N F ++ L ++ N LA
Sbjct: 322 FLRVLNVSQNLLETLEENVFSSPRALEVLSINNNPLA 358
Score = 59.7 bits (138), Expect = 8e-09
Identities = 43/170 (25%), Positives = 77/170 (45%), Gaps = 1/170 (0%)
Frame = -3
Query: 530 IKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRALP 354
+ +S N ++ F + P L + L + I + P F + LR+L L N+L+ +P
Sbjct: 62 LDLSKNRLKSVNPEEFISYPLLEEIDLSDNIIANVEPGAFNNLFNLRSLRLKGNRLKLVP 121
Query: 353 RSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTT 174
V G + LT L +S N + L +F DL L++ + N+L + FSGL +L
Sbjct: 122 LGVFTGLSNLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGLLSLEQ 181
Query: 173 VSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
++L ++ + S+ +L L + + P + L L L+
Sbjct: 182 LTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLE 231
Score = 42.7 bits (96), Expect = 0.001
Identities = 46/190 (24%), Positives = 86/190 (45%), Gaps = 3/190 (1%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISN-NVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EF 414
N Y+ F GL ++++ + N+ EA+ S+L +L +L L +I +P F
Sbjct: 163 NDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEAL-SHLRSLISLHLKHLNINNMPVYAF 221
Query: 413 ISNSPLRTLSLAR-NQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVM 237
L+ L + L +P + L G LTSL+++ ++ + F L L +
Sbjct: 222 KRLFHLKHLEIDYWPLLDMMPANSLYG-LNLTSLSVTNTNLSTVPFLAFKHLVYLTHLNL 280
Query: 236 DGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
N + + +FS L L + + ++ I ++FQG +R L++S N L +++
Sbjct: 281 SYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLRFLRVLNVSQNLLETLEENV 340
Query: 56 YSPLNQLHKL 27
+S L L
Sbjct: 341 FSSPRALEVL 350
Score = 31.1 bits (67), Expect = 3.1
Identities = 15/44 (34%), Positives = 27/44 (61%)
Frame = -3
Query: 578 RYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLD 447
R ++ F+GL ++ + +S N+ TL+E VFS+ AL L ++
Sbjct: 310 RTIEPHSFQGLRFLRVLNVSQNLLETLEENVFSSPRALEVLSIN 353
>AK172834-1|BAD18799.1| 459|Homo sapiens protein ( Homo sapiens
cDNA FLJ23995 fis, clone HRC11525. ).
Length = 459
Score = 64.1 bits (149), Expect = 4e-10
Identities = 41/157 (26%), Positives = 76/157 (48%), Gaps = 1/157 (0%)
Frame = -3
Query: 542 HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQL 366
H++ + I NN+P+ F L L+ L++D + ++ P + L +LS+ L
Sbjct: 60 HLKHLNI-NNMPVY----AFKRLFHLKHLEIDYWPLLDMMPANSLYGLNLTSLSVTNTNL 114
Query: 365 RALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLR 186
+P + LT L LSYN ++ + +F+DL L+ + G +L+ + F GLR
Sbjct: 115 STVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLR 174
Query: 185 NLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLA 75
L +++ N + + N F ++ L ++ N LA
Sbjct: 175 FLRVLNVSQNLLETLEENVFSSPRALEVLSINNNPLA 211
Score = 42.7 bits (96), Expect = 0.001
Identities = 46/190 (24%), Positives = 86/190 (45%), Gaps = 3/190 (1%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISN-NVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EF 414
N Y+ F GL ++++ + N+ EA+ S+L +L +L L +I +P F
Sbjct: 16 NDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEAL-SHLRSLISLHLKHLNINNMPVYAF 74
Query: 413 ISNSPLRTLSLAR-NQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVM 237
L+ L + L +P + L G LTSL+++ ++ + F L L +
Sbjct: 75 KRLFHLKHLEIDYWPLLDMMPANSLYG-LNLTSLSVTNTNLSTVPFLAFKHLVYLTHLNL 133
Query: 236 DGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
N + + +FS L L + + ++ I ++FQG +R L++S N L +++
Sbjct: 134 SYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLRFLRVLNVSQNLLETLEENV 193
Query: 56 YSPLNQLHKL 27
+S L L
Sbjct: 194 FSSPRALEVL 203
Score = 31.1 bits (67), Expect = 3.1
Identities = 15/44 (34%), Positives = 27/44 (61%)
Frame = -3
Query: 578 RYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLD 447
R ++ F+GL ++ + +S N+ TL+E VFS+ AL L ++
Sbjct: 163 RTIEPHSFQGLRFLRVLNVSQNLLETLEENVFSSPRALEVLSIN 206
Score = 30.7 bits (66), Expect = 4.1
Identities = 19/84 (22%), Positives = 37/84 (44%)
Frame = -3
Query: 275 LFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLD 96
+F DL L++ + N+L + FSGL +L ++L ++ + S+ +L
Sbjct: 1 MFQDLHNLKSLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRSLISLH 60
Query: 95 LSYNRLAFAPDSLYSPLNQLHKLQ 24
L + + P + L L L+
Sbjct: 61 LKHLNINNMPVYAFKRLFHLKHLE 84
>AK056372-1|BAB71167.1| 606|Homo sapiens protein ( Homo sapiens
cDNA FLJ31810 fis, clone NT2RI2009289, weakly similar to
CARBOXYPEPTIDASE N 83 KD CHAIN. ).
Length = 606
Score = 64.1 bits (149), Expect = 4e-10
Identities = 35/123 (28%), Positives = 66/123 (53%)
Frame = -3
Query: 395 RTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 216
+ L L++N+L+++ L + LS N +A + P F +L L + + GN L++
Sbjct: 60 KILDLSKNRLKSVNPEEFISYPLLEEIDLSDNIIANVEPGAFNNLFNLRSLRLKGNRLKL 119
Query: 215 LPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQL 36
+P +F+GL NLT + + NKI ++ FQ ++++L++ N L + +S L L
Sbjct: 120 VPLGVFTGLSNLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGLLSL 179
Query: 35 HKL 27
+L
Sbjct: 180 EQL 182
Score = 64.1 bits (149), Expect = 4e-10
Identities = 41/157 (26%), Positives = 76/157 (48%), Gaps = 1/157 (0%)
Frame = -3
Query: 542 HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQL 366
H++ + I NN+P+ F L L+ L++D + ++ P + L +LS+ L
Sbjct: 207 HLKHLNI-NNMPVY----AFKRLFHLKHLEIDYWPLLDMMPANSLYGLNLTSLSVTNTNL 261
Query: 365 RALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLR 186
+P + LT L LSYN ++ + +F+DL L+ + G +L+ + F GLR
Sbjct: 262 STVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLR 321
Query: 185 NLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLA 75
L +++ N + + N F ++ L ++ N LA
Sbjct: 322 FLRVLNVSQNLLETLEENVFSSPRALEVLSINNNPLA 358
Score = 59.7 bits (138), Expect = 8e-09
Identities = 43/170 (25%), Positives = 77/170 (45%), Gaps = 1/170 (0%)
Frame = -3
Query: 530 IKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRALP 354
+ +S N ++ F + P L + L + I + P F + LR+L L N+L+ +P
Sbjct: 62 LDLSKNRLKSVNPEEFISYPLLEEIDLSDNIIANVEPGAFNNLFNLRSLRLKGNRLKLVP 121
Query: 353 RSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTT 174
V G + LT L +S N + L +F DL L++ + N+L + FSGL +L
Sbjct: 122 LGVFTGLSNLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGLLSLEQ 181
Query: 173 VSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQ 24
++L ++ + S+ +L L + + P + L L L+
Sbjct: 182 LTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLE 231
Score = 42.7 bits (96), Expect = 0.001
Identities = 46/190 (24%), Positives = 86/190 (45%), Gaps = 3/190 (1%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISN-NVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EF 414
N Y+ F GL ++++ + N+ EA+ S+L +L +L L +I +P F
Sbjct: 163 NDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEAL-SHLRSLISLHLKHLNINNMPVYAF 221
Query: 413 ISNSPLRTLSLAR-NQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVM 237
L+ L + L +P + L G LTSL+++ ++ + F L L +
Sbjct: 222 KRLFHLKHLEIDYWPLLDMMPANSLYG-LNLTSLSVTNTNLSTVPFLAFKHLVYLTHLNL 280
Query: 236 DGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
N + + +FS L L + + ++ I ++FQG +R L++S N L +++
Sbjct: 281 SYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLRFLRVLNVSQNLLETLEENV 340
Query: 56 YSPLNQLHKL 27
+S L L
Sbjct: 341 FSSPRALEVL 350
Score = 31.1 bits (67), Expect = 3.1
Identities = 15/44 (34%), Positives = 27/44 (61%)
Frame = -3
Query: 578 RYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLD 447
R ++ F+GL ++ + +S N+ TL+E VFS+ AL L ++
Sbjct: 310 RTIEPHSFQGLRFLRVLNVSQNLLETLEENVFSSPRALEVLSIN 353
>BC126277-1|AAI26278.1| 1205|Homo sapiens PH domain and leucine rich
repeat protein phosphatase protein.
Length = 1205
Score = 63.7 bits (148), Expect = 5e-10
Identities = 45/149 (30%), Positives = 68/149 (45%), Gaps = 2/149 (1%)
Frame = -3
Query: 467 LRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAE 288
L L + + I ELP NS LR L NQL LP + R T + L + +N + E
Sbjct: 407 LEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPERLER--TSVEVLDVQHNQLLE 464
Query: 287 LAPELFADLRALETFVMDGNELQVLPDSLFSGLRN--LTTVSLRNNKISVISMNTFQGAT 114
L P L +L N+L+ LP + S N L + L NN ++ + G
Sbjct: 465 LPPNLLMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNSLTDKCVPLLTGHP 524
Query: 113 SIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
++ L ++YNRL P S + L +L ++
Sbjct: 525 HLKILHMAYNRLQSFPASKMAKLEELEEI 553
Score = 56.0 bits (129), Expect = 1e-07
Identities = 45/169 (26%), Positives = 78/169 (46%)
Frame = -3
Query: 539 IQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRA 360
++ + +SNN AV S +P L L + +++R +P L+T L N L++
Sbjct: 181 LKSLNLSNNHLGDFPLAVCS-IPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQS 239
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
LP L QL+ L LS+N ++ PE+ L A++ M GN ++ L + ++
Sbjct: 240 LPAE-LENMKQLSYLGLSFNEFTDI-PEVLEKLTAVDKLCMSGNCVETLRLQALRKMPHI 297
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLH 33
V LR N I + + + LDL N+L +++ + LH
Sbjct: 298 KHVDLRLNVIRKLIADEVDFLQHVTQLDLRDNKLGDLDAMIFNNIEVLH 346
Score = 56.0 bits (129), Expect = 1e-07
Identities = 50/182 (27%), Positives = 78/182 (42%), Gaps = 3/182 (1%)
Frame = -3
Query: 539 IQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS---NSPLRTLSLARNQ 369
++ + + +N L L + +LR L + + LP +S NS L+ L L N
Sbjct: 452 VEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNS 511
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
L +L G L L ++YN + A L LE + GN+L+ +P ++ +
Sbjct: 512 LTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMN-C 570
Query: 188 RNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLA 9
R + TV +N I V I+ +DLS N L+ + P N KLQ L L
Sbjct: 571 RRMHTVIAHSNCIEVFP--EVMQLPEIKCVDLSCNELS----EVTLPENLPPKLQELDLT 624
Query: 8 WN 3
N
Sbjct: 625 GN 626
>BC082244-1|AAH82244.1| 465|Homo sapiens PHLPP protein protein.
Length = 465
Score = 63.7 bits (148), Expect = 5e-10
Identities = 45/149 (30%), Positives = 68/149 (45%), Gaps = 2/149 (1%)
Frame = -3
Query: 467 LRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAE 288
L L + + I ELP NS LR L NQL LP + R T + L + +N + E
Sbjct: 143 LEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPERLER--TSVEVLDVQHNQLLE 200
Query: 287 LAPELFADLRALETFVMDGNELQVLPDSLFSGLRN--LTTVSLRNNKISVISMNTFQGAT 114
L P L +L N+L+ LP + S N L + L NN ++ + G
Sbjct: 201 LPPNLLMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNSLTDKCVPLLTGHP 260
Query: 113 SIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
++ L ++YNRL P S + L +L ++
Sbjct: 261 HLKILHMAYNRLQSFPASKMAKLEELEEI 289
Score = 56.0 bits (129), Expect = 1e-07
Identities = 50/182 (27%), Positives = 78/182 (42%), Gaps = 3/182 (1%)
Frame = -3
Query: 539 IQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS---NSPLRTLSLARNQ 369
++ + + +N L L + +LR L + + LP +S NS L+ L L N
Sbjct: 188 VEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNS 247
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
L +L G L L ++YN + A L LE + GN+L+ +P ++ +
Sbjct: 248 LTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMN-C 306
Query: 188 RNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLA 9
R + TV +N I V I+ +DLS N L+ + P N KLQ L L
Sbjct: 307 RRMHTVIAHSNCIEVFP--EVMQLPEIKCVDLSCNELS----EVTLPENLPPKLQELDLT 360
Query: 8 WN 3
N
Sbjct: 361 GN 362
>BC014927-1|AAH14927.3| 1205|Homo sapiens PH domain and leucine rich
repeat protein phosphatase protein.
Length = 1205
Score = 63.7 bits (148), Expect = 5e-10
Identities = 45/149 (30%), Positives = 68/149 (45%), Gaps = 2/149 (1%)
Frame = -3
Query: 467 LRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAE 288
L L + + I ELP NS LR L NQL LP + R T + L + +N + E
Sbjct: 407 LEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPERLER--TSVEVLDVQHNQLLE 464
Query: 287 LAPELFADLRALETFVMDGNELQVLPDSLFSGLRN--LTTVSLRNNKISVISMNTFQGAT 114
L P L +L N+L+ LP + S N L + L NN ++ + G
Sbjct: 465 LPPNLLMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNSLTDKCVPLLTGHP 524
Query: 113 SIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
++ L ++YNRL P S + L +L ++
Sbjct: 525 HLKILHMAYNRLQSFPASKMAKLEELEEI 553
Score = 56.0 bits (129), Expect = 1e-07
Identities = 45/169 (26%), Positives = 78/169 (46%)
Frame = -3
Query: 539 IQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRA 360
++ + +SNN AV S +P L L + +++R +P L+T L N L++
Sbjct: 181 LKSLNLSNNHLGDFPLAVCS-IPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQS 239
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
LP L QL+ L LS+N ++ PE+ L A++ M GN ++ L + ++
Sbjct: 240 LPAE-LENMKQLSYLGLSFNEFTDI-PEVLEKLTAVDKLCMSGNCVETLRLQALRKMPHI 297
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLH 33
V LR N I + + + LDL N+L +++ + LH
Sbjct: 298 KHVDLRLNVIRKLIADEVDFLQHVTQLDLRDNKLGDLDAMIFNNIEVLH 346
Score = 56.0 bits (129), Expect = 1e-07
Identities = 50/182 (27%), Positives = 78/182 (42%), Gaps = 3/182 (1%)
Frame = -3
Query: 539 IQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS---NSPLRTLSLARNQ 369
++ + + +N L L + +LR L + + LP +S NS L+ L L N
Sbjct: 452 VEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNS 511
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
L +L G L L ++YN + A L LE + GN+L+ +P ++ +
Sbjct: 512 LTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMN-C 570
Query: 188 RNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLA 9
R + TV +N I V I+ +DLS N L+ + P N KLQ L L
Sbjct: 571 RRMHTVIAHSNCIEVFP--EVMQLPEIKCVDLSCNELS----EVTLPENLPPKLQELDLT 624
Query: 8 WN 3
N
Sbjct: 625 GN 626
>AK001924-1|BAA91980.1| 721|Homo sapiens protein ( Homo sapiens
cDNA FLJ11062 fis, clone PLACE1004804, weakly similar to
ADENYLATE CYCLASE (EC 4.6.1.1). ).
Length = 721
Score = 63.7 bits (148), Expect = 5e-10
Identities = 45/149 (30%), Positives = 68/149 (45%), Gaps = 2/149 (1%)
Frame = -3
Query: 467 LRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAE 288
L L + + I ELP NS LR L NQL LP + R T + L + +N + E
Sbjct: 407 LEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPERLER--TSVEVLDVQHNQLLE 464
Query: 287 LAPELFADLRALETFVMDGNELQVLPDSLFSGLRN--LTTVSLRNNKISVISMNTFQGAT 114
L P L +L N+L+ LP + S N L + L NN ++ + G
Sbjct: 465 LPPNLLMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNSLTDKCVPLLTGHP 524
Query: 113 SIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
++ L ++YNRL P S + L +L ++
Sbjct: 525 HLKILHMAYNRLQSFPASKMAKLEELEEI 553
Score = 56.0 bits (129), Expect = 1e-07
Identities = 45/169 (26%), Positives = 78/169 (46%)
Frame = -3
Query: 539 IQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRA 360
++ + +SNN AV S +P L L + +++R +P L+T L N L++
Sbjct: 181 LKSLNLSNNHLGDFPLAVCS-IPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQS 239
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
LP L QL+ L LS+N ++ PE+ L A++ M GN ++ L + ++
Sbjct: 240 LPAE-LENMKQLSYLGLSFNEFTDI-PEVLEKLTAVDKLCMSGNCVETLRLQALRKMPHI 297
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLH 33
V LR N I + + + LDL N+L +++ + LH
Sbjct: 298 KHVDLRLNVIRKLIADEVDFLQHVTQLDLRDNKLGDLDAMIFNNIEVLH 346
Score = 56.0 bits (129), Expect = 1e-07
Identities = 50/182 (27%), Positives = 78/182 (42%), Gaps = 3/182 (1%)
Frame = -3
Query: 539 IQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS---NSPLRTLSLARNQ 369
++ + + +N L L + +LR L + + LP +S NS L+ L L N
Sbjct: 452 VEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNS 511
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
L +L G L L ++YN + A L LE + GN+L+ +P ++ +
Sbjct: 512 LTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMN-C 570
Query: 188 RNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLA 9
R + TV +N I V I+ +DLS N L+ + P N KLQ L L
Sbjct: 571 RRMHTVIAHSNCIEVFP--EVMQLPEIKCVDLSCNELS----EVTLPENLPPKLQELDLT 624
Query: 8 WN 3
N
Sbjct: 625 GN 626
>AC108017-1|AAY41039.1| 260|Homo sapiens unknown protein.
Length = 260
Score = 63.7 bits (148), Expect = 5e-10
Identities = 49/186 (26%), Positives = 79/186 (42%), Gaps = 2/186 (1%)
Frame = -3
Query: 587 NSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFI 411
N R L + F+ +Q++ + NN ++ F L +L L L + I L P F
Sbjct: 73 NLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFE 132
Query: 410 SNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPE-LFADLRALETFVMD 234
L L + N L + G L L L N + L + L + L ++
Sbjct: 133 DLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLE 192
Query: 233 GNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
GN + L + F NLT + +R NKI+ ++ NTF + LDL N++ P ++
Sbjct: 193 GNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIF 252
Query: 53 SPLNQL 36
L +L
Sbjct: 253 KDLKEL 258
Score = 48.0 bits (109), Expect = 3e-05
Identities = 24/68 (35%), Positives = 39/68 (57%)
Frame = -3
Query: 230 NELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYS 51
N ++ LP F +L + L+NNKI+ IS+ F+G S+ L LS+NR+ F ++
Sbjct: 73 NLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFE 132
Query: 50 PLNQLHKL 27
L++L L
Sbjct: 133 DLHRLEWL 140
>AB011178-1|BAA25532.2| 1369|Homo sapiens KIAA0606 protein protein.
Length = 1369
Score = 63.7 bits (148), Expect = 5e-10
Identities = 45/149 (30%), Positives = 68/149 (45%), Gaps = 2/149 (1%)
Frame = -3
Query: 467 LRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAE 288
L L + + I ELP NS LR L NQL LP + R T + L + +N + E
Sbjct: 571 LEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPERLER--TSVEVLDVQHNQLLE 628
Query: 287 LAPELFADLRALETFVMDGNELQVLPDSLFSGLRN--LTTVSLRNNKISVISMNTFQGAT 114
L P L +L N+L+ LP + S N L + L NN ++ + G
Sbjct: 629 LPPNLLMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNSLTDKCVPLLTGHP 688
Query: 113 SIRTLDLSYNRLAFAPDSLYSPLNQLHKL 27
++ L ++YNRL P S + L +L ++
Sbjct: 689 HLKILHMAYNRLQSFPASKMAKLEELEEI 717
Score = 56.0 bits (129), Expect = 1e-07
Identities = 45/169 (26%), Positives = 78/169 (46%)
Frame = -3
Query: 539 IQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRA 360
++ + +SNN AV S +P L L + +++R +P L+T L N L++
Sbjct: 345 LKSLNLSNNHLGDFPLAVCS-IPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQS 403
Query: 359 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
LP L QL+ L LS+N ++ PE+ L A++ M GN ++ L + ++
Sbjct: 404 LPAE-LENMKQLSYLGLSFNEFTDI-PEVLEKLTAVDKLCMSGNCVETLRLQALRKMPHI 461
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLH 33
V LR N I + + + LDL N+L +++ + LH
Sbjct: 462 KHVDLRLNVIRKLIADEVDFLQHVTQLDLRDNKLGDLDAMIFNNIEVLH 510
Score = 54.4 bits (125), Expect = 3e-07
Identities = 50/182 (27%), Positives = 78/182 (42%), Gaps = 3/182 (1%)
Frame = -3
Query: 539 IQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFIS---NSPLRTLSLARNQ 369
++ + + +N L L + +LR L + + LP +S NS L+ L L N
Sbjct: 616 VEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNS 675
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGL 189
L +L G L L ++YN + A L LE + GN+L+ +P ++ +
Sbjct: 676 LTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCS 735
Query: 188 RNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLA 9
R + TV +N I V I+ +DLS N L+ + P N KLQ L L
Sbjct: 736 R-MHTVIAHSNCIEVFP--EVMQLPEIKCVDLSCNELS----EVTLPENLPPKLQELDLT 788
Query: 8 WN 3
N
Sbjct: 789 GN 790
>M22403-1|AAA52596.1| 626|Homo sapiens platelet membrane
glycoprotein Ib-alpha protein.
Length = 626
Score = 63.3 bits (147), Expect = 6e-10
Identities = 42/124 (33%), Positives = 57/124 (45%)
Frame = -3
Query: 497 KEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTS 318
K V LP L TL L + ++ LP + L L ++ N+L +LP LRG +L
Sbjct: 85 KLQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQE 144
Query: 317 LTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVIS 138
L L N + L P L LE + N L LP L +GL NL T+ L+ N + I
Sbjct: 145 LYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIP 204
Query: 137 MNTF 126
F
Sbjct: 205 KGFF 208
Score = 62.9 bits (146), Expect = 8e-10
Identities = 49/161 (30%), Positives = 73/161 (45%), Gaps = 2/161 (1%)
Frame = -3
Query: 530 IKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPR 351
+ +S N+ T A L L LD + +L + + L TL L+ NQL++LP
Sbjct: 52 LHLSENLLYTFSLATLMPYTRLTQLNLDRCELTKLQVDG-TLPVLGTLDLSHNQLQSLP- 109
Query: 350 SVLRGQT--QLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLT 177
L GQT LT L +S+N + L L L+ + GNEL+ LP L + L
Sbjct: 110 --LLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPPGLLTPTPKLE 167
Query: 176 TVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
+SL NN ++ + G ++ TL L N L P +
Sbjct: 168 KLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFF 208
Score = 37.1 bits (82), Expect = 0.047
Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
Frame = -3
Query: 554 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLA 378
RGL +QE+ + N TL + + P L L L +++ ELP ++ L TL L
Sbjct: 137 RGLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQ 196
Query: 377 RNQLRALPR 351
N L +P+
Sbjct: 197 ENSLYTIPK 205
>J02940-1|AAA52595.1| 626|Homo sapiens GP1BA protein.
Length = 626
Score = 63.3 bits (147), Expect = 6e-10
Identities = 42/124 (33%), Positives = 57/124 (45%)
Frame = -3
Query: 497 KEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTS 318
K V LP L TL L + ++ LP + L L ++ N+L +LP LRG +L
Sbjct: 85 KLQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQE 144
Query: 317 LTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVIS 138
L L N + L P L LE + N L LP L +GL NL T+ L+ N + I
Sbjct: 145 LYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIP 204
Query: 137 MNTF 126
F
Sbjct: 205 KGFF 208
Score = 62.9 bits (146), Expect = 8e-10
Identities = 49/161 (30%), Positives = 73/161 (45%), Gaps = 2/161 (1%)
Frame = -3
Query: 530 IKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPR 351
+ +S N+ T A L L LD + +L + + L TL L+ NQL++LP
Sbjct: 52 LHLSENLLYTFSLATLMPYTRLTQLNLDRCELTKLQVDG-TLPVLGTLDLSHNQLQSLP- 109
Query: 350 SVLRGQT--QLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLT 177
L GQT LT L +S+N + L L L+ + GNEL+ LP L + L
Sbjct: 110 --LLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPPGLLTPTPKLE 167
Query: 176 TVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
+SL NN ++ + G ++ TL L N L P +
Sbjct: 168 KLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFF 208
Score = 37.1 bits (82), Expect = 0.047
Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
Frame = -3
Query: 554 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLA 378
RGL +QE+ + N TL + + P L L L +++ ELP ++ L TL L
Sbjct: 137 RGLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQ 196
Query: 377 RNQLRALPR 351
N L +P+
Sbjct: 197 ENSLYTIPK 205
>BC048421-1|AAH48421.1| 453|Homo sapiens LOC150356 protein protein.
Length = 453
Score = 63.3 bits (147), Expect = 6e-10
Identities = 49/187 (26%), Positives = 76/187 (40%), Gaps = 1/187 (0%)
Frame = -3
Query: 596 MMRNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
+ RN F + F GL H+ + + + L+ + L L L L + + L
Sbjct: 123 LRRNHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLSAA 182
Query: 416 FISNSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 240
+ +P L L L RN +P + LR L SL L NAV LAP RAL
Sbjct: 183 ALEGAPRLGYLYLERNSFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRWVY 242
Query: 239 MDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDS 60
+ GN + + R L + L N++ + +G ++ L LS N L D
Sbjct: 243 LSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDG 302
Query: 59 LYSPLNQ 39
+ P+ +
Sbjct: 303 AFQPVGR 309
Score = 42.7 bits (96), Expect = 0.001
Identities = 37/141 (26%), Positives = 58/141 (41%), Gaps = 1/141 (0%)
Frame = -3
Query: 476 LPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYNA 297
+P R + ++ +P F S++ L L L RN ++PR+ G L SL L +
Sbjct: 94 VPESRHSSCEGCGLQAVPRGFPSDTQL--LDLRRNHFPSVPRAAFPGLGHLVSLHLQHCG 151
Query: 296 VAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGA 117
+AEL A L L + N+L L + G L + L N + +
Sbjct: 152 IAELEAGALAGLGRLIYLYLSDNQLAGLSAAALEGAPRLGYLYLERNSFLQVPGAALRAL 211
Query: 116 TSIRTLDLSYNRL-AFAPDSL 57
S+ +L L N + AP L
Sbjct: 212 PSLFSLHLQDNAVDRLAPGDL 232
Score = 42.7 bits (96), Expect = 0.001
Identities = 33/100 (33%), Positives = 53/100 (53%), Gaps = 3/100 (3%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNVPLTLKEAVFSNLP-ALRTLQLDLSSIREL-PEE 417
RN R + + GL + E+++S N L++ F + +L+ L L+ S + ++ P
Sbjct: 269 RNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQHLFLNSSGLEQICPGA 328
Query: 416 FISNSP-LRTLSLARNQLRALPRSVLRGQTQLTSLTLSYN 300
F P L++L L +NQLRALP L +QL + LS N
Sbjct: 329 FSGLGPGLQSLHLQKNQLRALP--ALPSLSQLELIDLSSN 366
>BC027955-1|AAH27955.1| 626|Homo sapiens glycoprotein Ib
(platelet), alpha polypeptide protein.
Length = 626
Score = 63.3 bits (147), Expect = 6e-10
Identities = 42/124 (33%), Positives = 57/124 (45%)
Frame = -3
Query: 497 KEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTS 318
K V LP L TL L + ++ LP + L L ++ N+L +LP LRG +L
Sbjct: 85 KLQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQE 144
Query: 317 LTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVIS 138
L L N + L P L LE + N L LP L +GL NL T+ L+ N + I
Sbjct: 145 LYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIP 204
Query: 137 MNTF 126
F
Sbjct: 205 KGFF 208
Score = 62.9 bits (146), Expect = 8e-10
Identities = 49/161 (30%), Positives = 73/161 (45%), Gaps = 2/161 (1%)
Frame = -3
Query: 530 IKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPR 351
+ +S N+ T A L L LD + +L + + L TL L+ NQL++LP
Sbjct: 52 LHLSENLLYTFSLATLMPYTRLTQLNLDRCELTKLQVDG-TLPVLGTLDLSHNQLQSLP- 109
Query: 350 SVLRGQT--QLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLT 177
L GQT LT L +S+N + L L L+ + GNEL+ LP L + L
Sbjct: 110 --LLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPPGLLTPTPKLE 167
Query: 176 TVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
+SL NN ++ + G ++ TL L N L P +
Sbjct: 168 KLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFF 208
Score = 37.1 bits (82), Expect = 0.047
Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
Frame = -3
Query: 554 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLA 378
RGL +QE+ + N TL + + P L L L +++ ELP ++ L TL L
Sbjct: 137 RGLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQ 196
Query: 377 RNQLRALPR 351
N L +P+
Sbjct: 197 ENSLYTIPK 205
>AM709890-1|CAM97225.1| 639|Homo sapiens platelet glycoprotein Ib
alpha polypeptide protein.
Length = 639
Score = 63.3 bits (147), Expect = 6e-10
Identities = 42/124 (33%), Positives = 57/124 (45%)
Frame = -3
Query: 497 KEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTS 318
K V LP L TL L + ++ LP + L L ++ N+L +LP LRG +L
Sbjct: 85 KLQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQE 144
Query: 317 LTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVIS 138
L L N + L P L LE + N L LP L +GL NL T+ L+ N + I
Sbjct: 145 LYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIP 204
Query: 137 MNTF 126
F
Sbjct: 205 KGFF 208
Score = 62.9 bits (146), Expect = 8e-10
Identities = 49/161 (30%), Positives = 73/161 (45%), Gaps = 2/161 (1%)
Frame = -3
Query: 530 IKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPR 351
+ +S N+ T A L L LD + +L + + L TL L+ NQL++LP
Sbjct: 52 LHLSENLLYTFSLATLMPYTRLTQLNLDRCELTKLQVDG-TLPVLGTLDLSHNQLQSLP- 109
Query: 350 SVLRGQT--QLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLT 177
L GQT LT L +S+N + L L L+ + GNEL+ LP L + L
Sbjct: 110 --LLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPPGLLTPTPKLE 167
Query: 176 TVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
+SL NN ++ + G ++ TL L N L P +
Sbjct: 168 KLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFF 208
Score = 37.1 bits (82), Expect = 0.047
Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
Frame = -3
Query: 554 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLA 378
RGL +QE+ + N TL + + P L L L +++ ELP ++ L TL L
Sbjct: 137 RGLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQ 196
Query: 377 RNQLRALPR 351
N L +P+
Sbjct: 197 ENSLYTIPK 205
>AF395009-1|AAK71325.1| 626|Homo sapiens glycoprotein Ib
(platelet), alpha polypeptide protein.
Length = 626
Score = 63.3 bits (147), Expect = 6e-10
Identities = 42/124 (33%), Positives = 57/124 (45%)
Frame = -3
Query: 497 KEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTS 318
K V LP L TL L + ++ LP + L L ++ N+L +LP LRG +L
Sbjct: 85 KLQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQE 144
Query: 317 LTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVIS 138
L L N + L P L LE + N L LP L +GL NL T+ L+ N + I
Sbjct: 145 LYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIP 204
Query: 137 MNTF 126
F
Sbjct: 205 KGFF 208
Score = 62.9 bits (146), Expect = 8e-10
Identities = 49/161 (30%), Positives = 73/161 (45%), Gaps = 2/161 (1%)
Frame = -3
Query: 530 IKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPR 351
+ +S N+ T A L L LD + +L + + L TL L+ NQL++LP
Sbjct: 52 LHLSENLLYTFSLATLMPYTRLTQLNLDRCELTKLQVDG-TLPVLGTLDLSHNQLQSLP- 109
Query: 350 SVLRGQT--QLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLT 177
L GQT LT L +S+N + L L L+ + GNEL+ LP L + L
Sbjct: 110 --LLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPPGLLTPTPKLE 167
Query: 176 TVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
+SL NN ++ + G ++ TL L N L P +
Sbjct: 168 KLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFF 208
Score = 37.1 bits (82), Expect = 0.047
Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
Frame = -3
Query: 554 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLA 378
RGL +QE+ + N TL + + P L L L +++ ELP ++ L TL L
Sbjct: 137 RGLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQ 196
Query: 377 RNQLRALPR 351
N L +P+
Sbjct: 197 ENSLYTIPK 205
>AB086948-1|BAC10305.1| 626|Homo sapiens platelet glycoprotein Ib
alpha protein.
Length = 626
Score = 63.3 bits (147), Expect = 6e-10
Identities = 42/124 (33%), Positives = 57/124 (45%)
Frame = -3
Query: 497 KEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTS 318
K V LP L TL L + ++ LP + L L ++ N+L +LP LRG +L
Sbjct: 85 KLQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQE 144
Query: 317 LTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVIS 138
L L N + L P L LE + N L LP L +GL NL T+ L+ N + I
Sbjct: 145 LYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIP 204
Query: 137 MNTF 126
F
Sbjct: 205 KGFF 208
Score = 62.9 bits (146), Expect = 8e-10
Identities = 49/161 (30%), Positives = 73/161 (45%), Gaps = 2/161 (1%)
Frame = -3
Query: 530 IKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPR 351
+ +S N+ T A L L LD + +L + + L TL L+ NQL++LP
Sbjct: 52 LHLSENLLYTFSLATLMPYTRLTQLNLDRCELTKLQVDG-TLPVLGTLDLSHNQLQSLP- 109
Query: 350 SVLRGQT--QLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLT 177
L GQT LT L +S+N + L L L+ + GNEL+ LP L + L
Sbjct: 110 --LLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPPGLLTPTPKLE 167
Query: 176 TVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
+SL NN ++ + G ++ TL L N L P +
Sbjct: 168 KLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFF 208
Score = 37.1 bits (82), Expect = 0.047
Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
Frame = -3
Query: 554 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLA 378
RGL +QE+ + N TL + + P L L L +++ ELP ++ L TL L
Sbjct: 137 RGLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQ 196
Query: 377 RNQLRALPR 351
N L +P+
Sbjct: 197 ENSLYTIPK 205
>AB038516-1|BAB12038.1| 626|Homo sapiens platelet glycoprotein Ib
alpha protein.
Length = 626
Score = 63.3 bits (147), Expect = 6e-10
Identities = 42/124 (33%), Positives = 57/124 (45%)
Frame = -3
Query: 497 KEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTS 318
K V LP L TL L + ++ LP + L L ++ N+L +LP LRG +L
Sbjct: 85 KFQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQE 144
Query: 317 LTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVIS 138
L L N + L P L LE + N L LP L +GL NL T+ L+ N + I
Sbjct: 145 LYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIP 204
Query: 137 MNTF 126
F
Sbjct: 205 KGFF 208
Score = 62.5 bits (145), Expect = 1e-09
Identities = 50/162 (30%), Positives = 73/162 (45%), Gaps = 3/162 (1%)
Frame = -3
Query: 530 IKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLARNQLRALP 354
+ +S N+ T A +P R QL+L + P L TL L+ NQL++LP
Sbjct: 52 LHLSENLLYTFSLATL--MPYTRLTQLNLDRCELTKFQVDGTLPVLGTLDLSHNQLQSLP 109
Query: 353 RSVLRGQT--QLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNL 180
L GQT LT L +S+N + L L L+ + GNEL+ LP L + L
Sbjct: 110 ---LLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPPGLLTPTPKL 166
Query: 179 TTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSLY 54
+SL NN ++ + G ++ TL L N L P +
Sbjct: 167 EKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFF 208
Score = 37.1 bits (82), Expect = 0.047
Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
Frame = -3
Query: 554 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLA 378
RGL +QE+ + N TL + + P L L L +++ ELP ++ L TL L
Sbjct: 137 RGLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQ 196
Query: 377 RNQLRALPR 351
N L +P+
Sbjct: 197 ENSLYTIPK 205
>L12535-1|AAA60292.1| 277|Homo sapiens RSU-1 protein.
Length = 277
Score = 62.9 bits (146), Expect = 8e-10
Identities = 49/165 (29%), Positives = 77/165 (46%), Gaps = 1/165 (0%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L HI ++ +S+N LT+ + L L L + I ELP + S L+ L+L N+
Sbjct: 39 LSHITQLVLSHN-KLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNR 97
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELA-PELFADLRALETFVMDGNELQVLPDSLFSG 192
L LPR L L L+YN ++E + P F L L + N+ ++LP +
Sbjct: 98 LNTLPRG-FGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDI-GK 155
Query: 191 LRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
L L +SLR+N + + + T ++ L + NRL P L
Sbjct: 156 LTKLQILSLRDNDLISLPKEIGE-LTQLKELHIQGNRLTVLPPEL 199
>CR541840-1|CAG46639.1| 277|Homo sapiens RSU1 protein.
Length = 277
Score = 62.9 bits (146), Expect = 8e-10
Identities = 49/165 (29%), Positives = 77/165 (46%), Gaps = 1/165 (0%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L HI ++ +S+N LT+ + L L L + I ELP + S L+ L+L N+
Sbjct: 39 LSHITQLVLSHN-KLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNR 97
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELA-PELFADLRALETFVMDGNELQVLPDSLFSG 192
L LPR L L L+YN ++E + P F L L + N+ ++LP +
Sbjct: 98 LNTLPRG-FGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDI-GK 155
Query: 191 LRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
L L +SLR+N + + + T ++ L + NRL P L
Sbjct: 156 LTKLQILSLRDNDLISLPKEIGE-LTQLKELHIQGNRLTVLPPEL 199
>CR536521-1|CAG38758.1| 277|Homo sapiens RSU1 protein.
Length = 277
Score = 62.9 bits (146), Expect = 8e-10
Identities = 49/165 (29%), Positives = 77/165 (46%), Gaps = 1/165 (0%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L HI ++ +S+N LT+ + L L L + I ELP + S L+ L+L N+
Sbjct: 39 LSHITQLVLSHN-KLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNR 97
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELA-PELFADLRALETFVMDGNELQVLPDSLFSG 192
L LPR L L L+YN ++E + P F L L + N+ ++LP +
Sbjct: 98 LNTLPRG-FGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDI-GK 155
Query: 191 LRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
L L +SLR+N + + + T ++ L + NRL P L
Sbjct: 156 LTKLQILSLRDNDLISLPKEIGE-LTQLKELHIQGNRLTVLPPEL 199
>BC107898-1|AAI07899.1| 280|Homo sapiens RSU1 protein protein.
Length = 280
Score = 62.9 bits (146), Expect = 8e-10
Identities = 49/165 (29%), Positives = 77/165 (46%), Gaps = 1/165 (0%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L HI ++ +S+N LT+ + L L L + I ELP + S L+ L+L N+
Sbjct: 42 LSHITQLVLSHN-KLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNR 100
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELA-PELFADLRALETFVMDGNELQVLPDSLFSG 192
L LPR L L L+YN ++E + P F L L + N+ ++LP +
Sbjct: 101 LNTLPRG-FGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDI-GK 158
Query: 191 LRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
L L +SLR+N + + + T ++ L + NRL P L
Sbjct: 159 LTKLQILSLRDNDLISLPKEIGE-LTQLKELHIQGNRLTVLPPEL 202
>BC057786-1|AAH57786.1| 512|Homo sapiens podocan-like 1 protein.
Length = 512
Score = 62.9 bits (146), Expect = 8e-10
Identities = 48/151 (31%), Positives = 80/151 (52%), Gaps = 5/151 (3%)
Frame = -3
Query: 470 ALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRA--LPRSVLRGQTQLTSLTLSYN 300
A + L L + ++ELP +S S LRTL+L N + + LP TQL L +++N
Sbjct: 75 AAQHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHN 134
Query: 299 AVAELAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISM--NTF 126
++ +AP+ R+L + N++ + F L +V L NN++S + + F
Sbjct: 135 KLS-VAPQFLP--RSLRVADLAANQVMEIFPLTFGEKPALRSVYLHNNQLSNAGLPPDAF 191
Query: 125 QGATSIRTLDLSYNRLAFAPDSLYSPLNQLH 33
+G+ +I TL LS N+L++ P SL L +LH
Sbjct: 192 RGSEAIATLSLSNNQLSYLPPSLPPSLERLH 222
Score = 60.1 bits (139), Expect = 6e-09
Identities = 52/175 (29%), Positives = 79/175 (45%), Gaps = 4/175 (2%)
Frame = -3
Query: 590 RNSFRYLDSEIFRGLDHIQEIKISNNV--PLTLKEAVFSNLPALRTLQLDLSSIRELPEE 417
RN R +++ G ++ + + +N L L L TL L + + +P
Sbjct: 296 RNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPA 355
Query: 416 FISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLSYN--AVAELAPELFADLRALETF 243
LR L L N + AL L LT L L+YN A A + F LRAL +
Sbjct: 356 LPRR--LRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSL 413
Query: 242 VMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRL 78
+ GN+L LP L +GLR T+ L+ N++ ++ G +R L L++NRL
Sbjct: 414 DLAGNQLTRLPMGLPTGLR---TLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRL 465
Score = 59.3 bits (137), Expect = 1e-08
Identities = 48/157 (30%), Positives = 69/157 (43%), Gaps = 4/157 (2%)
Frame = -3
Query: 485 FSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLS 306
F A+ TL L + + LP + L L L N + +PR L QTQL L L
Sbjct: 191 FRGSEAIATLSLSNNQLSYLPPSLPPS--LERLHLQNNLISKVPRGALSRQTQLRELYLQ 248
Query: 305 YNAVAE--LAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISMN 132
+N + + L F+ L +LE + N+L +P L R L + L N+I +
Sbjct: 249 HNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGL---PRTLAILHLGRNRIRQVEAA 305
Query: 131 TFQGATSIRTLDLSYNRLAFA--PDSLYSPLNQLHKL 27
GA +R L L +N+L + P PL LH L
Sbjct: 306 RLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTL 342
Score = 53.2 bits (122), Expect = 7e-07
Identities = 49/168 (29%), Positives = 73/168 (43%), Gaps = 2/168 (1%)
Frame = -3
Query: 500 LKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLT 321
L FS L +L L L + + +P L L L RN++R + + L G L
Sbjct: 257 LDATTFSKLHSLEYLDLSHNQLTTVPAGLPRT--LAILHLGRNRIRQVEAARLHGARGLR 314
Query: 320 SLTLSYNAVAE--LAPELFADLRALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKIS 147
L L +N + L LR L T + GN L +P +L LR L L +N ++
Sbjct: 315 YLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALV---LPHNHVA 371
Query: 146 VISMNTFQGATSIRTLDLSYNRLAFAPDSLYSPLNQLHKLQTLTLAWN 3
+ + L+L+YNRLA A + +L L++L LA N
Sbjct: 372 ALGARDLVATPGLTELNLAYNRLASARVH-HRAFRRLRALRSLDLAGN 418
Score = 47.2 bits (107), Expect = 4e-05
Identities = 32/81 (39%), Positives = 45/81 (55%), Gaps = 2/81 (2%)
Frame = -3
Query: 485 FSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRALPRSVLRGQTQLTSLTLS 306
F L ALR+L L + + LP + LRTL L RNQLR L L G QL L+L+
Sbjct: 404 FRRLRALRSLDLAGNQLTRLPMGLPTG--LRTLQLQRNQLRMLEPEPLAGLDQLRELSLA 461
Query: 305 YN--AVAELAPELFADLRALE 249
+N V ++ P + +L+AL+
Sbjct: 462 HNRLRVGDIGPGTWHELQALQ 482
Score = 41.5 bits (93), Expect = 0.002
Identities = 24/70 (34%), Positives = 39/70 (55%), Gaps = 2/70 (2%)
Frame = -3
Query: 260 RALETFVMDGNELQVLPDSLFSGLRNLTTVSLRNNKISVISM--NTFQGATSIRTLDLSY 87
RA + + N+LQ LP + S L L T++L NN IS + F+ T ++ L +++
Sbjct: 74 RAAQHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAH 133
Query: 86 NRLAFAPDSL 57
N+L+ AP L
Sbjct: 134 NKLSVAPQFL 143
>BC015644-1|AAH15644.1| 277|Homo sapiens Ras suppressor protein 1
protein.
Length = 277
Score = 62.9 bits (146), Expect = 8e-10
Identities = 49/165 (29%), Positives = 77/165 (46%), Gaps = 1/165 (0%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L HI ++ +S+N LT+ + L L L + I ELP + S L+ L+L N+
Sbjct: 39 LSHITQLVLSHN-KLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNR 97
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELA-PELFADLRALETFVMDGNELQVLPDSLFSG 192
L LPR L L L+YN ++E + P F L L + N+ ++LP +
Sbjct: 98 LNTLPRG-FGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDI-GK 155
Query: 191 LRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
L L +SLR+N + + + T ++ L + NRL P L
Sbjct: 156 LTKLQILSLRDNDLISLPKEIGE-LTQLKELHIQGNRLTVLPPEL 199
>BC008691-1|AAH08691.1| 277|Homo sapiens RSU1 protein protein.
Length = 277
Score = 62.9 bits (146), Expect = 8e-10
Identities = 49/165 (29%), Positives = 77/165 (46%), Gaps = 1/165 (0%)
Frame = -3
Query: 548 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 369
L HI ++ +S+N LT+ + L L L + I ELP + S L+ L+L N+
Sbjct: 39 LSHITQLVLSHN-KLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNR 97
Query: 368 LRALPRSVLRGQTQLTSLTLSYNAVAELA-PELFADLRALETFVMDGNELQVLPDSLFSG 192
L LPR L L L+YN ++E + P F L L + N+ ++LP +
Sbjct: 98 LNTLPRG-FGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDI-GK 155
Query: 191 LRNLTTVSLRNNKISVISMNTFQGATSIRTLDLSYNRLAFAPDSL 57
L L +SLR+N + + + T ++ L + NRL P L
Sbjct: 156 LTKLQILSLRDNDLISLPKEIGE-LTQLKELHIQGNRLTVLPPEL 199
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 73,313,317
Number of Sequences: 237096
Number of extensions: 1391164
Number of successful extensions: 9885
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 6312
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8450
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6354183230
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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