Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= NV120839.seq
(692 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AK223041-1|BAD96761.1| 344|Homo sapiens methylene tetrahydrofol... 111 3e-24
X16396-1|CAA34431.1| 344|Homo sapiens protein ( Human mRNA for ... 110 4e-24
BC017054-1|AAH17054.2| 350|Homo sapiens methylenetetrahydrofola... 110 4e-24
BC001548-1|AAH01548.1| 344|Homo sapiens methylene tetrahydrofol... 110 4e-24
AK222826-1|BAD96546.1| 344|Homo sapiens methylene tetrahydrofol... 110 4e-24
AC073263-5|AAX93061.1| 344|Homo sapiens unknown protein. 110 4e-24
BC015062-1|AAH15062.1| 248|Homo sapiens methylenetetrahydrofola... 109 9e-24
BC032771-1|AAH32771.1| 146|Homo sapiens MTHFD2L protein protein. 97 5e-20
AK023167-1|BAB14441.1| 236|Homo sapiens ohydrolase (EC 1.5.1.15... 76 1e-13
BC037529-1|AAH37529.2| 106|Homo sapiens MTHFD2L protein protein. 71 5e-12
J04031-1|AAA59574.1| 935|Homo sapiens MTHFD protein. 69 2e-11
BC050420-1|AAH50420.1| 935|Homo sapiens methylenetetrahydrofola... 69 2e-11
BC009806-1|AAH09806.1| 935|Homo sapiens methylenetetrahydrofola... 69 2e-11
BC110319-1|AAI10320.1| 900|Homo sapiens MTHFD1L protein protein. 52 2e-06
AY374131-1|AAQ82697.1| 275|Homo sapiens truncated C1-tetrahydro... 52 2e-06
AY374130-1|AAQ82696.1| 978|Homo sapiens C1-tetrahydrofolate syn... 52 2e-06
AL133260-2|CAI95678.1| 978|Homo sapiens methylenetetrahydrofola... 52 2e-06
AL117452-1|CAB55934.1| 917|Homo sapiens hypothetical protein pr... 52 2e-06
AL049694-4|CAI95775.1| 331|Homo sapiens methylenetetrahydrofola... 52 2e-06
AL049694-3|CAI95774.1| 978|Homo sapiens methylenetetrahydrofola... 52 2e-06
AL035086-8|CAI42795.1| 331|Homo sapiens methylenetetrahydrofola... 52 2e-06
AL035086-7|CAI42794.1| 978|Homo sapiens methylenetetrahydrofola... 52 2e-06
AL035086-6|CAI42793.1| 114|Homo sapiens methylenetetrahydrofola... 52 2e-06
AB127387-1|BAD93193.1| 978|Homo sapiens mitochondrial C1-tetrah... 52 2e-06
AL035086-5|CAI42791.1| 120|Homo sapiens methylenetetrahydrofola... 36 0.14
AL035086-4|CAI42792.1| 120|Homo sapiens methylenetetrahydrofola... 36 0.14
AC097470-1|AAY40953.1| 43|Homo sapiens unknown protein. 32 1.7
BC128260-1|AAI28261.1| 657|Homo sapiens VIT protein protein. 30 9.0
AY358338-1|AAQ88704.1| 678|Homo sapiens VIT protein. 30 9.0
AK056772-1|BAB71279.1| 693|Homo sapiens protein ( Homo sapiens ... 30 9.0
AF063833-1|AAL18263.1| 656|Homo sapiens vitrin protein. 30 9.0
AC007363-1|AAF19243.2| 693|Homo sapiens unknown protein. 30 9.0
>AK223041-1|BAD96761.1| 344|Homo sapiens methylene tetrahydrofolate
dehydrogenase 2 precursor variant protein.
Length = 344
Score = 111 bits (266), Expect = 3e-24
Identities = 46/93 (49%), Positives = 73/93 (78%)
Frame = +2
Query: 230 ICGHRCININRDSDITEEQLLSEIQNLNEDNSVDGILVQLPVPDTINERRVCDAIAPEKD 409
+ G I + + I+EE+LL+ I LN D++VDG+LVQLP+P+ I+ERR+C+A++P+KD
Sbjct: 88 VAGINSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLPLPEHIDERRICNAVSPDKD 147
Query: 410 IDGFHIINIGRLCVDLPTIVPATALAVVEMLKR 508
+DGFH+IN+GR+C+D +++PAT V E++KR
Sbjct: 148 VDGFHVINVGRMCLDQYSMLPATPWGVWEIIKR 180
Score = 71.3 bits (167), Expect = 3e-12
Identities = 29/66 (43%), Positives = 48/66 (72%)
Frame = +3
Query: 60 ARILDGKALAMEIKKELKQKIAQWVGLGNRAPTIRCIIVGDDPASHTYVRNKVEAAKFVG 239
A ++ G+ LA +IK+E++Q++ +WV GN+ P + I+VG++PASH+YV NK AA G
Sbjct: 31 AVVISGRKLAQQIKQEVRQEVEEWVASGNKRPHLSVILVGENPASHSYVLNKTRAAAVAG 90
Query: 240 IDALTL 257
I++ T+
Sbjct: 91 INSETI 96
Score = 67.7 bits (158), Expect = 4e-11
Identities = 34/47 (72%), Positives = 36/47 (76%)
Frame = +3
Query: 537 VVIGRSKNVGMPIAMMLHSDKRHESGLGMDATVTICHRYTPKRQTWK 677
VV GRSKNVGMPIAM+LH+D HE G DATVTI HRYTPK Q K
Sbjct: 191 VVAGRSKNVGMPIAMLLHTDGAHERP-GGDATVTISHRYTPKEQLKK 236
>X16396-1|CAA34431.1| 344|Homo sapiens protein ( Human mRNA for
NAD-dependent methylene tetrahydrofolate dehydrogenase
cyclohydrolase (EC 1.5.1.15). ).
Length = 344
Score = 110 bits (265), Expect = 4e-24
Identities = 46/93 (49%), Positives = 73/93 (78%)
Frame = +2
Query: 230 ICGHRCININRDSDITEEQLLSEIQNLNEDNSVDGILVQLPVPDTINERRVCDAIAPEKD 409
+ G I + + I+EE+LL+ I LN D++VDG+LVQLP+P+ I+ERR+C+A++P+KD
Sbjct: 88 VVGINSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLPLPEHIDERRICNAVSPDKD 147
Query: 410 IDGFHIINIGRLCVDLPTIVPATALAVVEMLKR 508
+DGFH+IN+GR+C+D +++PAT V E++KR
Sbjct: 148 VDGFHVINVGRMCLDQYSMLPATPWGVWEIIKR 180
Score = 72.9 bits (171), Expect = 1e-12
Identities = 30/66 (45%), Positives = 49/66 (74%)
Frame = +3
Query: 60 ARILDGKALAMEIKKELKQKIAQWVGLGNRAPTIRCIIVGDDPASHTYVRNKVEAAKFVG 239
A ++ G+ LA +IK+E++Q++ +WV GN+ P + I+VG++PASH+YV NK AA VG
Sbjct: 31 AVVISGRKLAQQIKQEVRQEVEEWVASGNKRPHLSVILVGENPASHSYVLNKTRAAAVVG 90
Query: 240 IDALTL 257
I++ T+
Sbjct: 91 INSETI 96
Score = 67.7 bits (158), Expect = 4e-11
Identities = 34/47 (72%), Positives = 36/47 (76%)
Frame = +3
Query: 537 VVIGRSKNVGMPIAMMLHSDKRHESGLGMDATVTICHRYTPKRQTWK 677
VV GRSKNVGMPIAM+LH+D HE G DATVTI HRYTPK Q K
Sbjct: 191 VVAGRSKNVGMPIAMLLHTDGAHERP-GGDATVTISHRYTPKEQLKK 236
>BC017054-1|AAH17054.2| 350|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 2, methenyltetrahydro
protein.
Length = 350
Score = 110 bits (265), Expect = 4e-24
Identities = 46/93 (49%), Positives = 73/93 (78%)
Frame = +2
Query: 230 ICGHRCININRDSDITEEQLLSEIQNLNEDNSVDGILVQLPVPDTINERRVCDAIAPEKD 409
+ G I + + I+EE+LL+ I LN D++VDG+LVQLP+P+ I+ERR+C+A++P+KD
Sbjct: 94 VVGINSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLPLPEHIDERRICNAVSPDKD 153
Query: 410 IDGFHIINIGRLCVDLPTIVPATALAVVEMLKR 508
+DGFH+IN+GR+C+D +++PAT V E++KR
Sbjct: 154 VDGFHVINVGRMCLDQYSMLPATPWGVWEIIKR 186
Score = 72.9 bits (171), Expect = 1e-12
Identities = 30/66 (45%), Positives = 49/66 (74%)
Frame = +3
Query: 60 ARILDGKALAMEIKKELKQKIAQWVGLGNRAPTIRCIIVGDDPASHTYVRNKVEAAKFVG 239
A ++ G+ LA +IK+E++Q++ +WV GN+ P + I+VG++PASH+YV NK AA VG
Sbjct: 37 AVVISGRKLAQQIKQEVRQEVEEWVASGNKRPHLSVILVGENPASHSYVLNKTRAAAVVG 96
Query: 240 IDALTL 257
I++ T+
Sbjct: 97 INSETI 102
Score = 67.7 bits (158), Expect = 4e-11
Identities = 34/47 (72%), Positives = 36/47 (76%)
Frame = +3
Query: 537 VVIGRSKNVGMPIAMMLHSDKRHESGLGMDATVTICHRYTPKRQTWK 677
VV GRSKNVGMPIAM+LH+D HE G DATVTI HRYTPK Q K
Sbjct: 197 VVAGRSKNVGMPIAMLLHTDGAHERP-GGDATVTISHRYTPKEQLKK 242
>BC001548-1|AAH01548.1| 344|Homo sapiens methylene tetrahydrofolate
dehydrogenase 2, precursor protein.
Length = 344
Score = 110 bits (265), Expect = 4e-24
Identities = 46/93 (49%), Positives = 73/93 (78%)
Frame = +2
Query: 230 ICGHRCININRDSDITEEQLLSEIQNLNEDNSVDGILVQLPVPDTINERRVCDAIAPEKD 409
+ G I + + I+EE+LL+ I LN D++VDG+LVQLP+P+ I+ERR+C+A++P+KD
Sbjct: 88 VVGINSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLPLPEHIDERRICNAVSPDKD 147
Query: 410 IDGFHIINIGRLCVDLPTIVPATALAVVEMLKR 508
+DGFH+IN+GR+C+D +++PAT V E++KR
Sbjct: 148 VDGFHVINVGRMCLDQYSMLPATPWGVWEIIKR 180
Score = 72.9 bits (171), Expect = 1e-12
Identities = 30/66 (45%), Positives = 49/66 (74%)
Frame = +3
Query: 60 ARILDGKALAMEIKKELKQKIAQWVGLGNRAPTIRCIIVGDDPASHTYVRNKVEAAKFVG 239
A ++ G+ LA +IK+E++Q++ +WV GN+ P + I+VG++PASH+YV NK AA VG
Sbjct: 31 AVVISGRKLAQQIKQEVRQEVEEWVASGNKRPHLSVILVGENPASHSYVLNKTRAAAVVG 90
Query: 240 IDALTL 257
I++ T+
Sbjct: 91 INSETI 96
Score = 67.7 bits (158), Expect = 4e-11
Identities = 34/47 (72%), Positives = 36/47 (76%)
Frame = +3
Query: 537 VVIGRSKNVGMPIAMMLHSDKRHESGLGMDATVTICHRYTPKRQTWK 677
VV GRSKNVGMPIAM+LH+D HE G DATVTI HRYTPK Q K
Sbjct: 191 VVAGRSKNVGMPIAMLLHTDGAHERP-GGDATVTISHRYTPKEQLKK 236
>AK222826-1|BAD96546.1| 344|Homo sapiens methylene tetrahydrofolate
dehydrogenase 2 precursor variant protein.
Length = 344
Score = 110 bits (265), Expect = 4e-24
Identities = 46/93 (49%), Positives = 73/93 (78%)
Frame = +2
Query: 230 ICGHRCININRDSDITEEQLLSEIQNLNEDNSVDGILVQLPVPDTINERRVCDAIAPEKD 409
+ G I + + I+EE+LL+ I LN D++VDG+LVQLP+P+ I+ERR+C+A++P+KD
Sbjct: 88 VVGINSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLPLPEHIDERRICNAVSPDKD 147
Query: 410 IDGFHIINIGRLCVDLPTIVPATALAVVEMLKR 508
+DGFH+IN+GR+C+D +++PAT V E++KR
Sbjct: 148 VDGFHVINVGRMCLDQYSMLPATPWGVWEIIKR 180
Score = 71.3 bits (167), Expect = 3e-12
Identities = 29/66 (43%), Positives = 48/66 (72%)
Frame = +3
Query: 60 ARILDGKALAMEIKKELKQKIAQWVGLGNRAPTIRCIIVGDDPASHTYVRNKVEAAKFVG 239
A ++ G+ LA +IK+E++Q++ +WV GN+ P + I+ G++PASH+YV NK AA VG
Sbjct: 31 AVVISGRKLAQQIKQEVRQEVEEWVASGNKRPHLSVILAGENPASHSYVLNKTRAAAVVG 90
Query: 240 IDALTL 257
I++ T+
Sbjct: 91 INSETI 96
Score = 67.7 bits (158), Expect = 4e-11
Identities = 34/47 (72%), Positives = 36/47 (76%)
Frame = +3
Query: 537 VVIGRSKNVGMPIAMMLHSDKRHESGLGMDATVTICHRYTPKRQTWK 677
VV GRSKNVGMPIAM+LH+D HE G DATVTI HRYTPK Q K
Sbjct: 191 VVAGRSKNVGMPIAMLLHTDGAHERP-GGDATVTISHRYTPKEQLKK 236
>AC073263-5|AAX93061.1| 344|Homo sapiens unknown protein.
Length = 344
Score = 110 bits (265), Expect = 4e-24
Identities = 46/93 (49%), Positives = 73/93 (78%)
Frame = +2
Query: 230 ICGHRCININRDSDITEEQLLSEIQNLNEDNSVDGILVQLPVPDTINERRVCDAIAPEKD 409
+ G I + + I+EE+LL+ I LN D++VDG+LVQLP+P+ I+ERR+C+A++P+KD
Sbjct: 88 VVGINSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLPLPEHIDERRICNAVSPDKD 147
Query: 410 IDGFHIINIGRLCVDLPTIVPATALAVVEMLKR 508
+DGFH+IN+GR+C+D +++PAT V E++KR
Sbjct: 148 VDGFHVINVGRMCLDQYSMLPATPWGVWEIIKR 180
Score = 72.9 bits (171), Expect = 1e-12
Identities = 30/66 (45%), Positives = 49/66 (74%)
Frame = +3
Query: 60 ARILDGKALAMEIKKELKQKIAQWVGLGNRAPTIRCIIVGDDPASHTYVRNKVEAAKFVG 239
A ++ G+ LA +IK+E++Q++ +WV GN+ P + I+VG++PASH+YV NK AA VG
Sbjct: 31 AVVISGRKLAQQIKQEVRQEVEEWVASGNKRPHLSVILVGENPASHSYVLNKTRAAAVVG 90
Query: 240 IDALTL 257
I++ T+
Sbjct: 91 INSETI 96
Score = 67.7 bits (158), Expect = 4e-11
Identities = 34/47 (72%), Positives = 36/47 (76%)
Frame = +3
Query: 537 VVIGRSKNVGMPIAMMLHSDKRHESGLGMDATVTICHRYTPKRQTWK 677
VV GRSKNVGMPIAM+LH+D HE G DATVTI HRYTPK Q K
Sbjct: 191 VVAGRSKNVGMPIAMLLHTDGAHERP-GGDATVTISHRYTPKEQLKK 236
>BC015062-1|AAH15062.1| 248|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 2, methenyltetrahydro
protein.
Length = 248
Score = 109 bits (262), Expect = 9e-24
Identities = 44/83 (53%), Positives = 70/83 (84%)
Frame = +2
Query: 260 RDSDITEEQLLSEIQNLNEDNSVDGILVQLPVPDTINERRVCDAIAPEKDIDGFHIINIG 439
+ + I+EE+LL+ I LN D++VDG+LVQLP+P+ I+ERR+C+A++P+KD+DGFH+IN+G
Sbjct: 2 KPASISEEELLNLINKLNNDDNVDGLLVQLPLPEHIDERRICNAVSPDKDVDGFHVINVG 61
Query: 440 RLCVDLPTIVPATALAVVEMLKR 508
R+C+D +++PAT V E++KR
Sbjct: 62 RMCLDQYSMLPATPWGVWEIIKR 84
Score = 67.7 bits (158), Expect = 4e-11
Identities = 34/47 (72%), Positives = 36/47 (76%)
Frame = +3
Query: 537 VVIGRSKNVGMPIAMMLHSDKRHESGLGMDATVTICHRYTPKRQTWK 677
VV GRSKNVGMPIAM+LH+D HE G DATVTI HRYTPK Q K
Sbjct: 95 VVAGRSKNVGMPIAMLLHTDGAHERP-GGDATVTISHRYTPKEQLKK 140
>BC032771-1|AAH32771.1| 146|Homo sapiens MTHFD2L protein protein.
Length = 146
Score = 97.1 bits (231), Expect = 5e-20
Identities = 42/64 (65%), Positives = 54/64 (84%)
Frame = +2
Query: 317 DNSVDGILVQLPVPDTINERRVCDAIAPEKDIDGFHIINIGRLCVDLPTIVPATALAVVE 496
D V GILVQLP+PD ++ER +C+ IAPEKD+DGFHIINIGRLC+D +++PATA AV E
Sbjct: 2 DPRVSGILVQLPLPDHVDERTICNGIAPEKDVDGFHIINIGRLCLDQHSLIPATASAVWE 61
Query: 497 MLKR 508
++KR
Sbjct: 62 IIKR 65
Score = 68.1 bits (159), Expect = 3e-11
Identities = 33/44 (75%), Positives = 35/44 (79%)
Frame = +3
Query: 537 VVIGRSKNVGMPIAMMLHSDKRHESGLGMDATVTICHRYTPKRQ 668
VV GRSKNVGMPIAM+LH+D HE G DATVTI HRYTPK Q
Sbjct: 76 VVAGRSKNVGMPIAMLLHTDGEHERP-GGDATVTIAHRYTPKEQ 118
>AK023167-1|BAB14441.1| 236|Homo sapiens ohydrolase (EC 1.5.1.15).
protein.
Length = 236
Score = 75.8 bits (178), Expect = 1e-13
Identities = 31/48 (64%), Positives = 42/48 (87%)
Frame = +2
Query: 365 INERRVCDAIAPEKDIDGFHIINIGRLCVDLPTIVPATALAVVEMLKR 508
++ER +C+ IAPEKD+DGFHIINIGRLC+D +++PATA AV E++KR
Sbjct: 42 VDERTICNGIAPEKDVDGFHIINIGRLCLDQHSLIPATASAVWEIIKR 89
Score = 68.1 bits (159), Expect = 3e-11
Identities = 33/44 (75%), Positives = 35/44 (79%)
Frame = +3
Query: 537 VVIGRSKNVGMPIAMMLHSDKRHESGLGMDATVTICHRYTPKRQ 668
VV GRSKNVGMPIAM+LH+D HE G DATVTI HRYTPK Q
Sbjct: 100 VVAGRSKNVGMPIAMLLHTDGEHERP-GGDATVTIAHRYTPKEQ 142
>BC037529-1|AAH37529.2| 106|Homo sapiens MTHFD2L protein protein.
Length = 106
Score = 70.5 bits (165), Expect = 5e-12
Identities = 30/53 (56%), Positives = 40/53 (75%)
Frame = +3
Query: 84 LAMEIKKELKQKIAQWVGLGNRAPTIRCIIVGDDPASHTYVRNKVEAAKFVGI 242
+A I+KE+++ + WV LGNR P + I+VGD+PASHTYVRNK+ AA VGI
Sbjct: 1 MAKHIQKEIQRGVESWVSLGNRRPHLSIILVGDNPASHTYVRNKIRAASAVGI 53
Score = 39.5 bits (88), Expect = 0.011
Identities = 17/38 (44%), Positives = 25/38 (65%)
Frame = +2
Query: 254 INRDSDITEEQLLSEIQNLNEDNSVDGILVQLPVPDTI 367
I + D+++E+LL LN D V GILVQLP+P+ +
Sbjct: 58 ILKPKDVSQEELLDVTDQLNMDPRVSGILVQLPLPEAV 95
>J04031-1|AAA59574.1| 935|Homo sapiens MTHFD protein.
Length = 935
Score = 68.5 bits (160), Expect = 2e-11
Identities = 42/112 (37%), Positives = 62/112 (55%), Gaps = 8/112 (7%)
Frame = +2
Query: 236 GHRCININRDSDITEEQLLSEIQNLNEDNSVDGILVQLPVP--DTINERRVCDAIAPEKD 409
G + +I TE +++ I +LNED++V G LVQLP+ ++IN V +AIAPEKD
Sbjct: 64 GIKATHIKLPRTTTESEVMKYITSLNEDSTVHGFLVQLPLDSENSINTEEVINAIAPEKD 123
Query: 410 IDGFHIINIGRLC-VDL-PTIVPATALAVVEMLKR----LTSTHSVATXRDR 547
+DG IN GRL DL +P T +E++K + H+V R +
Sbjct: 124 VDGLTSINAGRLARGDLNDCFIPCTPKGCLELIKETGVPIAGRHAVVVGRSK 175
>BC050420-1|AAH50420.1| 935|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1, methenyltetrahydro
protein.
Length = 935
Score = 68.5 bits (160), Expect = 2e-11
Identities = 42/112 (37%), Positives = 62/112 (55%), Gaps = 8/112 (7%)
Frame = +2
Query: 236 GHRCININRDSDITEEQLLSEIQNLNEDNSVDGILVQLPVP--DTINERRVCDAIAPEKD 409
G + +I TE +++ I +LNED++V G LVQLP+ ++IN V +AIAPEKD
Sbjct: 64 GIKATHIKLPRTTTESEVMKYITSLNEDSTVHGFLVQLPLDSENSINTEEVINAIAPEKD 123
Query: 410 IDGFHIINIGRLC-VDL-PTIVPATALAVVEMLKR----LTSTHSVATXRDR 547
+DG IN GRL DL +P T +E++K + H+V R +
Sbjct: 124 VDGLTSINAGRLARGDLNDCFIPCTPKGCLELIKETGVPIAGRHAVVVGRSK 175
>BC009806-1|AAH09806.1| 935|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1, methenyltetrahydro
protein.
Length = 935
Score = 68.5 bits (160), Expect = 2e-11
Identities = 42/112 (37%), Positives = 62/112 (55%), Gaps = 8/112 (7%)
Frame = +2
Query: 236 GHRCININRDSDITEEQLLSEIQNLNEDNSVDGILVQLPVP--DTINERRVCDAIAPEKD 409
G + +I TE +++ I +LNED++V G LVQLP+ ++IN V +AIAPEKD
Sbjct: 64 GIKATHIKLPRTTTESEVMKYITSLNEDSTVHGFLVQLPLDSENSINTEEVINAIAPEKD 123
Query: 410 IDGFHIINIGRLC-VDL-PTIVPATALAVVEMLKR----LTSTHSVATXRDR 547
+DG IN GRL DL +P T +E++K + H+V R +
Sbjct: 124 VDGLTSINAGRLARGDLNDCFIPCTPKGCLELIKETGVPIAGRHAVVVGRSK 175
>BC110319-1|AAI10320.1| 900|Homo sapiens MTHFD1L protein protein.
Length = 900
Score = 52.0 bits (119), Expect = 2e-06
Identities = 28/82 (34%), Positives = 48/82 (58%), Gaps = 2/82 (2%)
Frame = +2
Query: 269 DITEEQLLSEIQNLNEDNSVDGILVQLPVPDTINERRVCDAIAPEKDIDGFHIINIGRLC 448
D +E +++ EI +NED V G+ +Q + + + +V +A+ PEKD+DG IN+G+L
Sbjct: 56 DSSEAEIIDEILKINEDTRVHGLALQ--ISENLFSNKVLNALKPEKDVDGVTDINLGKLV 113
Query: 449 VD--LPTIVPATALAVVEMLKR 508
V A AV+E+L++
Sbjct: 114 RGDAHECFVSPVAKAVIELLEK 135
>AY374131-1|AAQ82697.1| 275|Homo sapiens truncated
C1-tetrahydrofolate synthase protein.
Length = 275
Score = 52.0 bits (119), Expect = 2e-06
Identities = 28/82 (34%), Positives = 48/82 (58%), Gaps = 2/82 (2%)
Frame = +2
Query: 269 DITEEQLLSEIQNLNEDNSVDGILVQLPVPDTINERRVCDAIAPEKDIDGFHIINIGRLC 448
D +E +++ EI +NED V G+ +Q + + + +V +A+ PEKD+DG IN+G+L
Sbjct: 134 DSSEAEIIDEILKINEDTRVHGLALQ--ISENLFSNKVLNALKPEKDVDGVTDINLGKLV 191
Query: 449 VD--LPTIVPATALAVVEMLKR 508
V A AV+E+L++
Sbjct: 192 RGDAHECFVSPVAKAVIELLEK 213
>AY374130-1|AAQ82696.1| 978|Homo sapiens C1-tetrahydrofolate
synthase protein.
Length = 978
Score = 52.0 bits (119), Expect = 2e-06
Identities = 28/82 (34%), Positives = 48/82 (58%), Gaps = 2/82 (2%)
Frame = +2
Query: 269 DITEEQLLSEIQNLNEDNSVDGILVQLPVPDTINERRVCDAIAPEKDIDGFHIINIGRLC 448
D +E +++ EI +NED V G+ +Q + + + +V +A+ PEKD+DG IN+G+L
Sbjct: 134 DSSEAEIIDEILKINEDTRVHGLALQ--ISENLFSNKVLNALKPEKDVDGVTDINLGKLV 191
Query: 449 VD--LPTIVPATALAVVEMLKR 508
V A AV+E+L++
Sbjct: 192 RGDAHECFVSPVAKAVIELLEK 213
>AL133260-2|CAI95678.1| 978|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1-like protein.
Length = 978
Score = 52.0 bits (119), Expect = 2e-06
Identities = 28/82 (34%), Positives = 48/82 (58%), Gaps = 2/82 (2%)
Frame = +2
Query: 269 DITEEQLLSEIQNLNEDNSVDGILVQLPVPDTINERRVCDAIAPEKDIDGFHIINIGRLC 448
D +E +++ EI +NED V G+ +Q + + + +V +A+ PEKD+DG IN+G+L
Sbjct: 134 DSSEAEIIDEILKINEDTRVHGLALQ--ISENLFSNKVLNALKPEKDVDGVTDINLGKLV 191
Query: 449 VD--LPTIVPATALAVVEMLKR 508
V A AV+E+L++
Sbjct: 192 RGDAHECFVSPVAKAVIELLEK 213
>AL117452-1|CAB55934.1| 917|Homo sapiens hypothetical protein
protein.
Length = 917
Score = 52.0 bits (119), Expect = 2e-06
Identities = 28/82 (34%), Positives = 48/82 (58%), Gaps = 2/82 (2%)
Frame = +2
Query: 269 DITEEQLLSEIQNLNEDNSVDGILVQLPVPDTINERRVCDAIAPEKDIDGFHIINIGRLC 448
D +E +++ EI +NED V G+ +Q + + + +V +A+ PEKD+DG IN+G+L
Sbjct: 73 DSSEAEIIDEILKINEDTRVHGLALQ--ISENLFSNKVLNALKPEKDVDGVTDINLGKLV 130
Query: 449 VD--LPTIVPATALAVVEMLKR 508
V A AV+E+L++
Sbjct: 131 RGDAHECFVSPVAKAVIELLEK 152
>AL049694-4|CAI95775.1| 331|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1-like protein.
Length = 331
Score = 52.0 bits (119), Expect = 2e-06
Identities = 28/82 (34%), Positives = 48/82 (58%), Gaps = 2/82 (2%)
Frame = +2
Query: 269 DITEEQLLSEIQNLNEDNSVDGILVQLPVPDTINERRVCDAIAPEKDIDGFHIINIGRLC 448
D +E +++ EI +NED V G+ +Q + + + +V +A+ PEKD+DG IN+G+L
Sbjct: 93 DSSEAEIIDEILKINEDTRVHGLALQ--ISENLFSNKVLNALKPEKDVDGVTDINLGKLV 150
Query: 449 VD--LPTIVPATALAVVEMLKR 508
V A AV+E+L++
Sbjct: 151 RGDAHECFVSPVAKAVIELLEK 172
>AL049694-3|CAI95774.1| 978|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1-like protein.
Length = 978
Score = 52.0 bits (119), Expect = 2e-06
Identities = 28/82 (34%), Positives = 48/82 (58%), Gaps = 2/82 (2%)
Frame = +2
Query: 269 DITEEQLLSEIQNLNEDNSVDGILVQLPVPDTINERRVCDAIAPEKDIDGFHIINIGRLC 448
D +E +++ EI +NED V G+ +Q + + + +V +A+ PEKD+DG IN+G+L
Sbjct: 134 DSSEAEIIDEILKINEDTRVHGLALQ--ISENLFSNKVLNALKPEKDVDGVTDINLGKLV 191
Query: 449 VD--LPTIVPATALAVVEMLKR 508
V A AV+E+L++
Sbjct: 192 RGDAHECFVSPVAKAVIELLEK 213
>AL035086-8|CAI42795.1| 331|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1-like protein.
Length = 331
Score = 52.0 bits (119), Expect = 2e-06
Identities = 28/82 (34%), Positives = 48/82 (58%), Gaps = 2/82 (2%)
Frame = +2
Query: 269 DITEEQLLSEIQNLNEDNSVDGILVQLPVPDTINERRVCDAIAPEKDIDGFHIINIGRLC 448
D +E +++ EI +NED V G+ +Q + + + +V +A+ PEKD+DG IN+G+L
Sbjct: 93 DSSEAEIIDEILKINEDTRVHGLALQ--ISENLFSNKVLNALKPEKDVDGVTDINLGKLV 150
Query: 449 VD--LPTIVPATALAVVEMLKR 508
V A AV+E+L++
Sbjct: 151 RGDAHECFVSPVAKAVIELLEK 172
>AL035086-7|CAI42794.1| 978|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1-like protein.
Length = 978
Score = 52.0 bits (119), Expect = 2e-06
Identities = 28/82 (34%), Positives = 48/82 (58%), Gaps = 2/82 (2%)
Frame = +2
Query: 269 DITEEQLLSEIQNLNEDNSVDGILVQLPVPDTINERRVCDAIAPEKDIDGFHIINIGRLC 448
D +E +++ EI +NED V G+ +Q + + + +V +A+ PEKD+DG IN+G+L
Sbjct: 134 DSSEAEIIDEILKINEDTRVHGLALQ--ISENLFSNKVLNALKPEKDVDGVTDINLGKLV 191
Query: 449 VD--LPTIVPATALAVVEMLKR 508
V A AV+E+L++
Sbjct: 192 RGDAHECFVSPVAKAVIELLEK 213
>AL035086-6|CAI42793.1| 114|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1-like protein.
Length = 114
Score = 52.0 bits (119), Expect = 2e-06
Identities = 28/82 (34%), Positives = 48/82 (58%), Gaps = 2/82 (2%)
Frame = +2
Query: 269 DITEEQLLSEIQNLNEDNSVDGILVQLPVPDTINERRVCDAIAPEKDIDGFHIINIGRLC 448
D +E +++ EI +NED V G+ +Q + + + +V +A+ PEKD+DG IN+G+L
Sbjct: 24 DSSEAEIIDEILKINEDTRVHGLALQ--ISENLFSNKVLNALKPEKDVDGVTDINLGKLV 81
Query: 449 VD--LPTIVPATALAVVEMLKR 508
V A AV+E+L++
Sbjct: 82 RGDAHECFVSPVAKAVIELLEK 103
>AB127387-1|BAD93193.1| 978|Homo sapiens mitochondrial
C1-tetrahydrofolate synthetase protein.
Length = 978
Score = 52.0 bits (119), Expect = 2e-06
Identities = 28/82 (34%), Positives = 48/82 (58%), Gaps = 2/82 (2%)
Frame = +2
Query: 269 DITEEQLLSEIQNLNEDNSVDGILVQLPVPDTINERRVCDAIAPEKDIDGFHIINIGRLC 448
D +E +++ EI +NED V G+ +Q + + + +V +A+ PEKD+DG IN+G+L
Sbjct: 134 DSSEAEIIDEILKINEDTRVHGLALQ--ISENLFSNKVLNALKPEKDVDGVTDINLGKLV 191
Query: 449 VD--LPTIVPATALAVVEMLKR 508
V A AV+E+L++
Sbjct: 192 RGDAHECFVSPVAKAVIELLEK 213
>AL035086-5|CAI42791.1| 120|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1-like protein.
Length = 120
Score = 35.9 bits (79), Expect = 0.14
Identities = 19/56 (33%), Positives = 32/56 (57%), Gaps = 2/56 (3%)
Frame = +2
Query: 347 LPVPDTINERRVCDAIAPEKDIDGFHIINIGRLCVD--LPTIVPATALAVVEMLKR 508
L + + + +V +A+ PEKD+DG IN+G+L V A AV+E+L++
Sbjct: 2 LQISENLFSNKVLNALKPEKDVDGVTDINLGKLVRGDAHECFVSPVAKAVIELLEK 57
>AL035086-4|CAI42792.1| 120|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1-like protein.
Length = 120
Score = 35.9 bits (79), Expect = 0.14
Identities = 19/56 (33%), Positives = 32/56 (57%), Gaps = 2/56 (3%)
Frame = +2
Query: 347 LPVPDTINERRVCDAIAPEKDIDGFHIINIGRLCVD--LPTIVPATALAVVEMLKR 508
L + + + +V +A+ PEKD+DG IN+G+L V A AV+E+L++
Sbjct: 3 LQISENLFSNKVLNALKPEKDVDGVTDINLGKLVRGDAHECFVSPVAKAVIELLEK 58
>AC097470-1|AAY40953.1| 43|Homo sapiens unknown protein.
Length = 43
Score = 32.3 bits (70), Expect = 1.7
Identities = 13/15 (86%), Positives = 13/15 (86%)
Frame = +3
Query: 624 DATVTICHRYTPKRQ 668
DATVTI HRYTPK Q
Sbjct: 1 DATVTIAHRYTPKEQ 15
>BC128260-1|AAI28261.1| 657|Homo sapiens VIT protein protein.
Length = 657
Score = 29.9 bits (64), Expect = 9.0
Identities = 19/74 (25%), Positives = 35/74 (47%), Gaps = 1/74 (1%)
Frame = +3
Query: 45 NFIIMARILDGKALAMEIKKELKQKIAQWVGLGNRAPTIRCIIVGDDPASHTYVRNKVEA 224
+F+I GK I+K+L +AQ + +G P + + GD+PA+H ++ +
Sbjct: 274 SFLIDGSTSIGKR-RFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTNS 332
Query: 225 AKF-VGIDALTLTG 263
I+ +T G
Sbjct: 333 RDLKTAIEKITQRG 346
>AY358338-1|AAQ88704.1| 678|Homo sapiens VIT protein.
Length = 678
Score = 29.9 bits (64), Expect = 9.0
Identities = 19/74 (25%), Positives = 35/74 (47%), Gaps = 1/74 (1%)
Frame = +3
Query: 45 NFIIMARILDGKALAMEIKKELKQKIAQWVGLGNRAPTIRCIIVGDDPASHTYVRNKVEA 224
+F+I GK I+K+L +AQ + +G P + + GD+PA+H ++ +
Sbjct: 295 SFLIDGSTSIGKR-RFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTNS 353
Query: 225 AKF-VGIDALTLTG 263
I+ +T G
Sbjct: 354 RDLKTAIEKITQRG 367
>AK056772-1|BAB71279.1| 693|Homo sapiens protein ( Homo sapiens
cDNA FLJ32210 fis, clone PLACE6003383, weakly similar to
COCHLIN PRECURSOR. ).
Length = 693
Score = 29.9 bits (64), Expect = 9.0
Identities = 19/74 (25%), Positives = 35/74 (47%), Gaps = 1/74 (1%)
Frame = +3
Query: 45 NFIIMARILDGKALAMEIKKELKQKIAQWVGLGNRAPTIRCIIVGDDPASHTYVRNKVEA 224
+F+I GK I+K+L +AQ + +G P + + GD+PA+H ++ +
Sbjct: 310 SFLIDGSTSIGKR-RFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTNS 368
Query: 225 AKF-VGIDALTLTG 263
I+ +T G
Sbjct: 369 RDLKTAIEKITQRG 382
>AF063833-1|AAL18263.1| 656|Homo sapiens vitrin protein.
Length = 656
Score = 29.9 bits (64), Expect = 9.0
Identities = 19/74 (25%), Positives = 35/74 (47%), Gaps = 1/74 (1%)
Frame = +3
Query: 45 NFIIMARILDGKALAMEIKKELKQKIAQWVGLGNRAPTIRCIIVGDDPASHTYVRNKVEA 224
+F+I GK I+K+L +AQ + +G P + + GD+PA+H ++ +
Sbjct: 273 SFLIDGSTSIGKR-RFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTNS 331
Query: 225 AKF-VGIDALTLTG 263
I+ +T G
Sbjct: 332 RDLKTAIEKITQRG 345
>AC007363-1|AAF19243.2| 693|Homo sapiens unknown protein.
Length = 693
Score = 29.9 bits (64), Expect = 9.0
Identities = 19/74 (25%), Positives = 35/74 (47%), Gaps = 1/74 (1%)
Frame = +3
Query: 45 NFIIMARILDGKALAMEIKKELKQKIAQWVGLGNRAPTIRCIIVGDDPASHTYVRNKVEA 224
+F+I GK I+K+L +AQ + +G P + + GD+PA+H ++ +
Sbjct: 310 SFLIDGSTSIGKR-RFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTNS 368
Query: 225 AKF-VGIDALTLTG 263
I+ +T G
Sbjct: 369 RDLKTAIEKITQRG 382
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 106,443,955
Number of Sequences: 237096
Number of extensions: 2296757
Number of successful extensions: 4281
Number of sequences better than 10.0: 32
Number of HSP's better than 10.0 without gapping: 4168
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4266
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7951235188
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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