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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= NV120615.seq
         (694 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q16R44 Cluster: Putative uncharacterized protein; n=3; ...   108   1e-22
UniRef50_Q6DBH4 Cluster: At2g23820; n=10; Magnoliophyta|Rep: At2...   105   1e-21
UniRef50_UPI0000E21170 Cluster: PREDICTED: similar to HDDC2 prot...   103   3e-21
UniRef50_Q9BTT2 Cluster: HD domain-containing protein 2; n=22; E...   103   3e-21
UniRef50_Q9VMB3 Cluster: CG11050-PA, isoform A; n=8; Endopterygo...   102   1e-20
UniRef50_P87242 Cluster: HD domain; n=1; Schizosaccharomyces pom...   100   4e-20
UniRef50_UPI00006CB3F6 Cluster: HD domain containing protein; n=...    95   1e-18
UniRef50_Q54FK1 Cluster: Putative uncharacterized protein; n=1; ...    91   2e-17
UniRef50_A2EW86 Cluster: HD domain containing protein; n=1; Tric...    90   5e-17
UniRef50_Q00SL1 Cluster: Predicted hydrolases of HD superfamily;...    89   1e-16
UniRef50_A3LQW0 Cluster: Predicted protein; n=6; Saccharomycetal...    85   2e-15
UniRef50_Q4PHJ8 Cluster: Putative uncharacterized protein; n=1; ...    84   4e-15
UniRef50_P38331 Cluster: Uncharacterized protein YBR242W; n=10; ...    83   5e-15
UniRef50_UPI000023F3D1 Cluster: hypothetical protein FG08678.1; ...    83   6e-15
UniRef50_A0DPT1 Cluster: Chromosome undetermined scaffold_59, wh...    81   3e-14
UniRef50_Q6CED3 Cluster: Similar to sp|P38331 Saccharomyces cere...    79   1e-13
UniRef50_Q55UE1 Cluster: Putative uncharacterized protein; n=2; ...    78   2e-13
UniRef50_Q0U692 Cluster: Putative uncharacterized protein; n=1; ...    76   1e-12
UniRef50_UPI00004988B4 Cluster: metal dependent phosphohydrolase...    75   2e-12
UniRef50_Q08WG0 Cluster: Metal-dependent phosphohydrolase, HD su...    73   7e-12
UniRef50_Q4X103 Cluster: HD family hydrolase, putative; n=12; Pe...    73   9e-12
UniRef50_A4RGR2 Cluster: Putative uncharacterized protein; n=2; ...    73   9e-12
UniRef50_Q8LQ52 Cluster: Metal-dependent phosphohydrolase HD dom...    71   3e-11
UniRef50_A4IBV0 Cluster: Putative uncharacterized protein; n=5; ...    68   2e-10
UniRef50_Q3IT40 Cluster: Putative uncharacterized protein; n=1; ...    67   4e-10
UniRef50_Q9UY89 Cluster: Metal-dependent phosphohydrolase, putat...    64   3e-09
UniRef50_Q9Y3D1 Cluster: CGI-130 protein; n=4; Eutheria|Rep: CGI...    59   1e-07
UniRef50_Q7R6E7 Cluster: GLP_574_17393_16761; n=1; Giardia lambl...    58   2e-07
UniRef50_A5UYG9 Cluster: Metal dependent phosphohydrolase; n=2; ...    58   3e-07
UniRef50_O52019 Cluster: Putative uncharacterized protein; n=1; ...    56   8e-07
UniRef50_Q3DW72 Cluster: Metal-dependent phosphohydrolase, HD su...    54   3e-06
UniRef50_A7DMD6 Cluster: Metal dependent phosphohydrolase; n=1; ...    54   3e-06
UniRef50_Q192N4 Cluster: HD domain protein; n=2; Desulfitobacter...    53   6e-06
UniRef50_Q8TZ99 Cluster: Predicted hydrolase of the HD superfami...    53   6e-06
UniRef50_Q0W115 Cluster: Predicted metal-dependent phosphohydrol...    53   6e-06
UniRef50_A7D845 Cluster: Metal-dependent phosphohydrolase, HD su...    53   6e-06
UniRef50_A6PNY3 Cluster: Metal dependent phosphohydrolase; n=1; ...    53   8e-06
UniRef50_A6D2I3 Cluster: Putative uncharacterized protein; n=2; ...    53   8e-06
UniRef50_Q399M0 Cluster: Metal-dependent phosphohydrolase; n=18;...    52   1e-05
UniRef50_Q1MS33 Cluster: Putative uncharacterized protein LI0136...    52   2e-05
UniRef50_Q8U3R1 Cluster: Oxetanocin-like protein; n=2; Thermococ...    51   2e-05
UniRef50_A0RU59 Cluster: HD superfamily hydrolase; n=2; Thermopr...    51   2e-05
UniRef50_Q7N1B9 Cluster: Similar to unknown protein; n=7; Entero...    50   4e-05
UniRef50_Q3EUQ7 Cluster: Hydrolase; n=12; Bacillus|Rep: Hydrolas...    50   5e-05
UniRef50_Q0FP87 Cluster: HD domain protein; n=10; Proteobacteria...    48   2e-04
UniRef50_Q62CP8 Cluster: HD domain protein; n=18; Proteobacteria...    48   2e-04
UniRef50_Q099G6 Cluster: Metal-dependent phosphohydrolase, HD su...    48   2e-04
UniRef50_Q9Y9C8 Cluster: Putative uncharacterized protein; n=1; ...    48   2e-04
UniRef50_Q73R17 Cluster: HD domain protein; n=1; Treponema denti...    48   3e-04
UniRef50_A6XS73 Cluster: Metal-dependent phosphohydrolase, HD su...    48   3e-04
UniRef50_Q6LQV5 Cluster: Putative uncharacterized protein BA1657...    47   4e-04
UniRef50_Q5WZR1 Cluster: Putative uncharacterized protein; n=4; ...    47   4e-04
UniRef50_Q1GH96 Cluster: HD domain protein; n=6; Rhodobacteracea...    47   4e-04
UniRef50_A5KNZ3 Cluster: Putative uncharacterized protein; n=4; ...    47   4e-04
UniRef50_A0NM90 Cluster: Metal dependent phosphohydrolase; n=2; ...    46   9e-04
UniRef50_A7B2L5 Cluster: Putative uncharacterized protein; n=1; ...    46   0.001
UniRef50_A4BKM6 Cluster: Possible metal dependent phosphohydrola...    45   0.002
UniRef50_A3CNR6 Cluster: Hydrolase, putative; n=2; Streptococcus...    45   0.002
UniRef50_A7CNS4 Cluster: Metal dependent phosphohydrolase; n=3; ...    44   0.003
UniRef50_Q9R6H4 Cluster: Tiorf85 protein; n=1; Agrobacterium tum...    44   0.004
UniRef50_Q1ZH93 Cluster: Predicted hydrolase; n=5; Gammaproteoba...    44   0.004
UniRef50_A1DAC9 Cluster: Putative uncharacterized protein; n=1; ...    44   0.004
UniRef50_Q895R8 Cluster: Hydrolase; n=6; Clostridiales|Rep: Hydr...    44   0.005
UniRef50_A5FA91 Cluster: Metal dependent phosphohydrolase; n=2; ...    44   0.005
UniRef50_Q4FQC9 Cluster: Possible metal dependent phosphohydrola...    43   0.006
UniRef50_Q1LGM8 Cluster: Hydrolases of HD superfamily-like prote...    43   0.006
UniRef50_A4FQR8 Cluster: Metal-dependent phosphohydrolase, HD re...    43   0.006
UniRef50_Q1K3X2 Cluster: Metal dependent phosphohydrolase; n=4; ...    43   0.008
UniRef50_Q4JA64 Cluster: Conserved Archaeal protein; n=4; Sulfol...    42   0.011
UniRef50_A7JP66 Cluster: Predicted protein; n=1; Francisella tul...    42   0.014
UniRef50_A3JYJ9 Cluster: HD domain protein; n=1; Sagittula stell...    42   0.014
UniRef50_Q2SNR5 Cluster: Predicted Hydrolase of HD superfamily; ...    41   0.025
UniRef50_Q22973 Cluster: Putative uncharacterized protein; n=2; ...    41   0.025
UniRef50_Q4SC46 Cluster: Chromosome 14 SCAF14660, whole genome s...    41   0.033
UniRef50_UPI00006CA3B0 Cluster: hypothetical protein TTHERM_0052...    40   0.044
UniRef50_Q5BRU0 Cluster: SJCHGC07393 protein; n=1; Schistosoma j...    40   0.058
UniRef50_Q47TN5 Cluster: Metal-dependent phosphohydrolase, HD re...    38   0.18 
UniRef50_A6BZR0 Cluster: Metal dependent phosphohydrolase; n=1; ...    38   0.23 
UniRef50_A6BKU8 Cluster: Putative uncharacterized protein; n=2; ...    38   0.23 
UniRef50_Q4HMC9 Cluster: ATP-dependent nuclease (AddB), putative...    38   0.31 
UniRef50_A1G3Q4 Cluster: Metal dependent phosphohydrolase; n=4; ...    38   0.31 
UniRef50_A0Q525 Cluster: Hydrolase, HD superfamily; n=12; Franci...    38   0.31 
UniRef50_A2BL70 Cluster: Predicted hydrolase of HD superfamily; ...    38   0.31 
UniRef50_Q6M9P4 Cluster: Putative uncharacterized protein; n=1; ...    36   0.71 
UniRef50_Q23UG8 Cluster: Peptidase M16 inactive domain containin...    36   0.71 
UniRef50_A1RZE6 Cluster: Metal dependent phosphohydrolase; n=1; ...    36   0.71 
UniRef50_A6CJT6 Cluster: Putative uncharacterized protein; n=1; ...    35   1.6  
UniRef50_A0DXX1 Cluster: Chromosome undetermined scaffold_69, wh...    35   1.6  
UniRef50_Q4Y5N6 Cluster: Putative uncharacterized protein; n=1; ...    34   3.8  
UniRef50_P11532 Cluster: Dystrophin; n=138; Eukaryota|Rep: Dystr...    34   3.8  
UniRef50_Q9RWG4 Cluster: Putative uncharacterized protein; n=1; ...    33   5.0  
UniRef50_Q16YM0 Cluster: Cohesin-subunit, putative; n=3; Culicid...    33   5.0  
UniRef50_A2FC18 Cluster: Rap/ran-GAP family protein; n=1; Tricho...    33   5.0  
UniRef50_Q971B8 Cluster: V-type ATP synthase subunit E; n=2; Sul...    33   5.0  
UniRef50_Q10071 Cluster: Probable CAAX prenyl protease 1; n=1; S...    33   5.0  
UniRef50_Q20EV4 Cluster: Putative septum site-determining protei...    33   5.0  
UniRef50_A7MRB0 Cluster: Putative uncharacterized protein; n=1; ...    33   6.6  
UniRef50_A0Y8H0 Cluster: Alpha/beta hydrolase fold protein; n=6;...    33   6.6  
UniRef50_Q19007 Cluster: Putative uncharacterized protein; n=2; ...    33   6.6  
UniRef50_Q6FSY5 Cluster: Similar to sp|P47069 Saccharomyces cere...    33   6.6  
UniRef50_Q7VI11 Cluster: Putative uncharacterized protein; n=1; ...    33   8.8  
UniRef50_A3YEP7 Cluster: Possible metal dependent phosphohydrola...    33   8.8  
UniRef50_Q23DV3 Cluster: Plasmid Maintenance Protein containing ...    33   8.8  
UniRef50_P52387 Cluster: Virion protein U50; n=6; Roseolovirus|R...    33   8.8  

>UniRef50_Q16R44 Cluster: Putative uncharacterized protein; n=3;
           Aedes aegypti|Rep: Putative uncharacterized protein -
           Aedes aegypti (Yellowfever mosquito)
          Length = 264

 Score =  108 bits (260), Expect = 1e-22
 Identities = 47/85 (55%), Positives = 66/85 (77%)
 Frame = +1

Query: 253 ILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGIAGDRMYELYKEYED 432
           ++++AL+HDLAE IVGD+TP+CG+S EEK  +E  A+  I+ L G   +++ EL+ EYE+
Sbjct: 116 VMELALVHDLAESIVGDITPYCGISREEKLLKEFSAISEIAELLGPNKEKLLELFNEYEE 175

Query: 433 QSSPEAKFAKDLDRYDMILQAFEYE 507
             +PEAKF KDLDR DM++QAFEYE
Sbjct: 176 GKTPEAKFVKDLDRLDMVMQAFEYE 200



 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 28/45 (62%), Positives = 36/45 (80%)
 Frame = +2

Query: 116 KHVKRTGWILCDINDCETIAGHMYRMGIMTFLLTEENNPTKLDRI 250
           KH KRTGW+L ++ DCETI+GHMYRMG+M+FLL  + +   LDRI
Sbjct: 73  KHTKRTGWVLRNVKDCETISGHMYRMGMMSFLLDGQQD---LDRI 114



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 22/43 (51%), Positives = 30/43 (69%)
 Frame = +3

Query: 507 KRENTPKKCQEFFTATEGKFDHPFIQDLVKELYLQREIFEKHT 635
           KR+N P K QEFF +T+GKF HP + ++V E+  QRE F + T
Sbjct: 201 KRDNCPMKHQEFFDSTKGKFSHPLVINIVNEINAQRERFAEAT 243


>UniRef50_Q6DBH4 Cluster: At2g23820; n=10; Magnoliophyta|Rep:
           At2g23820 - Arabidopsis thaliana (Mouse-ear cress)
          Length = 257

 Score =  105 bits (251), Expect = 1e-21
 Identities = 48/93 (51%), Positives = 71/93 (76%), Gaps = 3/93 (3%)
 Frame = +1

Query: 238 IGQNKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGIAGDR---MY 408
           + ++K +++A++HD+AE IVGD+TP CG+S EEK+RRE EA++ +  L G  G+R   + 
Sbjct: 128 VNRDKCMKMAIVHDIAEAIVGDITPSCGISKEEKNRRESEALEHMCKLLG-GGERAKEIA 186

Query: 409 ELYKEYEDQSSPEAKFAKDLDRYDMILQAFEYE 507
           EL++EYE+ SSPEAK  KD D+ ++ILQA EYE
Sbjct: 187 ELWREYEENSSPEAKVVKDFDKVELILQALEYE 219



 Score = 42.3 bits (95), Expect = 0.011
 Identities = 24/60 (40%), Positives = 32/60 (53%)
 Frame = +2

Query: 41  VKSSSCL*CSESRIKLLFITQYFSKKHVKRTGWILCDINDCETIAGHMYRMGIMTFLLTE 220
           V SSS    + S I  L +      K   R GWI  D+ D E+IA HMYRMG+M  + ++
Sbjct: 67  VPSSSSSSSASSAIDFLSLCTRL--KTTPRAGWIKRDVKDPESIADHMYRMGLMALISSD 124


>UniRef50_UPI0000E21170 Cluster: PREDICTED: similar to HDDC2
           protein; n=1; Pan troglodytes|Rep: PREDICTED: similar to
           HDDC2 protein - Pan troglodytes
          Length = 282

 Score =  103 bits (248), Expect = 3e-21
 Identities = 49/94 (52%), Positives = 70/94 (74%), Gaps = 1/94 (1%)
 Frame = +1

Query: 238 IGQNKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISG-LTGIAGDRMYEL 414
           + +++ +++AL+HD+AECIVGD+ P   +  EEKHRRE+EAMK I+  L       +YEL
Sbjct: 129 LNKDRCVRLALVHDMAECIVGDIAPADNIPKEEKHRREEEAMKQITQLLPEDLRKELYEL 188

Query: 415 YKEYEDQSSPEAKFAKDLDRYDMILQAFEYENVK 516
           ++EYE QSS EAKF K LD+ +MILQA EYE+++
Sbjct: 189 WEEYETQSSAEAKFVKQLDQCEMILQASEYEDLE 222



 Score = 39.9 bits (89), Expect = 0.058
 Identities = 16/50 (32%), Positives = 29/50 (58%)
 Frame = +2

Query: 74  SRIKLLFITQYFSKKHVKRTGWILCDINDCETIAGHMYRMGIMTFLLTEE 223
           +R  L F+      K V RTGW+  ++   E+++ HMYRM +M  ++ ++
Sbjct: 78  ARSLLQFLRLVGQLKRVPRTGWVYRNVQRPESVSDHMYRMAVMAMVIKDD 127


>UniRef50_Q9BTT2 Cluster: HD domain-containing protein 2; n=22;
           Eumetazoa|Rep: HD domain-containing protein 2 - Homo
           sapiens (Human)
          Length = 218

 Score =  103 bits (248), Expect = 3e-21
 Identities = 49/94 (52%), Positives = 70/94 (74%), Gaps = 1/94 (1%)
 Frame = +1

Query: 238 IGQNKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISG-LTGIAGDRMYEL 414
           + +++ +++AL+HD+AECIVGD+ P   +  EEKHRRE+EAMK I+  L       +YEL
Sbjct: 79  LNKDRCVRLALVHDMAECIVGDIAPADNIPKEEKHRREEEAMKQITQLLPEDLRKELYEL 138

Query: 415 YKEYEDQSSPEAKFAKDLDRYDMILQAFEYENVK 516
           ++EYE QSS EAKF K LD+ +MILQA EYE+++
Sbjct: 139 WEEYETQSSAEAKFVKQLDQCEMILQASEYEDLE 172



 Score = 39.9 bits (89), Expect = 0.058
 Identities = 16/50 (32%), Positives = 29/50 (58%)
 Frame = +2

Query: 74  SRIKLLFITQYFSKKHVKRTGWILCDINDCETIAGHMYRMGIMTFLLTEE 223
           +R  L F+      K V RTGW+  ++   E+++ HMYRM +M  ++ ++
Sbjct: 28  ARSLLQFLRLVGQLKRVPRTGWVYRNVQRPESVSDHMYRMAVMAMVIKDD 77



 Score = 37.9 bits (84), Expect = 0.23
 Identities = 16/34 (47%), Positives = 23/34 (67%)
 Frame = +3

Query: 513 ENTPKKCQEFFTATEGKFDHPFIQDLVKELYLQR 614
           E+ P + Q+F+ +T GKF+HP I  LV EL  +R
Sbjct: 172 EHKPGRLQDFYDSTAGKFNHPEIVQLVSELEAER 205


>UniRef50_Q9VMB3 Cluster: CG11050-PA, isoform A; n=8;
           Endopterygota|Rep: CG11050-PA, isoform A - Drosophila
           melanogaster (Fruit fly)
          Length = 388

 Score =  102 bits (244), Expect = 1e-20
 Identities = 45/90 (50%), Positives = 65/90 (72%)
 Frame = +1

Query: 238 IGQNKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGIAGDRMYELY 417
           + Q + +++AL+HDLAE +VGD+TP CG+S ++K   E +AM+ I  L    G R+ EL+
Sbjct: 229 LNQIRCMELALVHDLAESLVGDITPFCGISKDDKRAMEFKAMEDICKLIEPRGKRIMELF 288

Query: 418 KEYEDQSSPEAKFAKDLDRYDMILQAFEYE 507
           +EYE   + E+KF KDLDR DM++QAFEYE
Sbjct: 289 EEYEHGQTAESKFVKDLDRLDMVMQAFEYE 318



 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 26/43 (60%), Positives = 34/43 (79%)
 Frame = +2

Query: 86  LLFITQYFSKKHVKRTGWILCDINDCETIAGHMYRMGIMTFLL 214
           L F+    + KH KRTGW+L D+NDCE+I+GHMYRM ++TFLL
Sbjct: 181 LQFMELIGNLKHTKRTGWVLRDVNDCESISGHMYRMSMLTFLL 223



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 23/41 (56%), Positives = 31/41 (75%)
 Frame = +3

Query: 507 KRENTPKKCQEFFTATEGKFDHPFIQDLVKELYLQREIFEK 629
           KR+N   K QEFF +TEGKF+HPF++ LV E+Y QR++  K
Sbjct: 319 KRDNCLLKHQEFFDSTEGKFNHPFVKKLVNEIYEQRDVLAK 359


>UniRef50_P87242 Cluster: HD domain; n=1; Schizosaccharomyces
           pombe|Rep: HD domain - Schizosaccharomyces pombe
           (Fission yeast)
          Length = 198

 Score =  100 bits (239), Expect = 4e-20
 Identities = 48/95 (50%), Positives = 66/95 (69%), Gaps = 5/95 (5%)
 Frame = +1

Query: 238 IGQNKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGL-----TGIAGDR 402
           I + + L+IA++HD+AE IVGD+TPH  VS EEKHR E EAM +I+         +  + 
Sbjct: 57  INKERCLKIAVVHDMAESIVGDITPHENVSKEEKHRMESEAMVSITQQLIPLNLSLQAEE 116

Query: 403 MYELYKEYEDQSSPEAKFAKDLDRYDMILQAFEYE 507
           + EL+ EYE  S+PEAKF KD+D+++MI Q FEYE
Sbjct: 117 IKELFLEYESASTPEAKFVKDIDKFEMIAQMFEYE 151



 Score = 40.7 bits (91), Expect = 0.033
 Identities = 18/35 (51%), Positives = 22/35 (62%)
 Frame = +2

Query: 116 KHVKRTGWILCDINDCETIAGHMYRMGIMTFLLTE 220
           K   RTGW+   I   E+IA HMYRMGI+T L  +
Sbjct: 20  KTTPRTGWLYHGIEKPESIADHMYRMGILTMLCND 54


>UniRef50_UPI00006CB3F6 Cluster: HD domain containing protein; n=1;
           Tetrahymena thermophila SB210|Rep: HD domain containing
           protein - Tetrahymena thermophila SB210
          Length = 330

 Score = 95.5 bits (227), Expect = 1e-18
 Identities = 43/90 (47%), Positives = 65/90 (72%), Gaps = 4/90 (4%)
 Frame = +1

Query: 250 KILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGIAG----DRMYELY 417
           + ++ A+IHDLAE IVGD+TP  G+S ++KH+ EDE +K +  L+ I      D +Y ++
Sbjct: 186 RCIKFAIIHDLAEVIVGDITPRDGISEDQKHKMEDEGIKLL--LSKIENQEIRDELYSIW 243

Query: 418 KEYEDQSSPEAKFAKDLDRYDMILQAFEYE 507
           K+YED+  PE+K  KD+DR++M+ QAFEYE
Sbjct: 244 KQYEDRKCPESKLVKDMDRFEMMQQAFEYE 273


>UniRef50_Q54FK1 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 190

 Score = 91.5 bits (217), Expect = 2e-17
 Identities = 42/91 (46%), Positives = 65/91 (71%), Gaps = 1/91 (1%)
 Frame = +1

Query: 238 IGQNKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISG-LTGIAGDRMYEL 414
           I + KI+++AL+HDL E +VGD TPH  ++ EEK++ E  A+  I+  L+G  G  +++L
Sbjct: 60  IDKMKIIKMALVHDLGESLVGDFTPHDKITKEEKYQLEKNAIIEITNTLSGEVGKEIFDL 119

Query: 415 YKEYEDQSSPEAKFAKDLDRYDMILQAFEYE 507
           ++EYED  + EA   KD D+++MILQA+EYE
Sbjct: 120 WQEYEDCKTNEALLVKDFDKFEMILQAYEYE 150



 Score = 35.5 bits (78), Expect = 1.2
 Identities = 17/53 (32%), Positives = 31/53 (58%), Gaps = 4/53 (7%)
 Frame = +2

Query: 116 KHVKRTGWILCDINDCETIAGHMYRMGIMTFLLTEE----NNPTKLDRIKFFK 262
           K +KRTGW+   +   E+++ HMYRM +M   L ++     +  ++D++K  K
Sbjct: 15  KTLKRTGWVNHGVELPESVSDHMYRMAMMGMCLDKKELIGEDGKEIDKMKIIK 67


>UniRef50_A2EW86 Cluster: HD domain containing protein; n=1;
           Trichomonas vaginalis G3|Rep: HD domain containing
           protein - Trichomonas vaginalis G3
          Length = 181

 Score = 89.8 bits (213), Expect = 5e-17
 Identities = 42/93 (45%), Positives = 67/93 (72%)
 Frame = +1

Query: 238 IGQNKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGIAGDRMYELY 417
           + ++K +Q+ALIHDLAE IV D+TP  GV+ E+K  RE++A + I    G   D M++++
Sbjct: 53  VNKDKAVQMALIHDLAESIVSDITPFDGVTLEDKFNRENKAWQHICDSLG--NDEMHKIW 110

Query: 418 KEYEDQSSPEAKFAKDLDRYDMILQAFEYENVK 516
            E E++ +PEAKF  +LD+ +M++QA EYEN++
Sbjct: 111 LEMEERKTPEAKFVTELDKLEMLIQAEEYENLQ 143


>UniRef50_Q00SL1 Cluster: Predicted hydrolases of HD superfamily;
           n=2; Ostreococcus|Rep: Predicted hydrolases of HD
           superfamily - Ostreococcus tauri
          Length = 198

 Score = 88.6 bits (210), Expect = 1e-16
 Identities = 41/91 (45%), Positives = 60/91 (65%)
 Frame = +1

Query: 238 IGQNKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGIAGDRMYELY 417
           +   + +++AL+HDLAEC+VGD+TP  GVS ++KH  E  AM  +    G  G  + EL+
Sbjct: 67  VDSTRAVKMALVHDLAECVVGDITPCDGVSDDDKHAMEKRAMDDLVKDLGSVGLEVLELW 126

Query: 418 KEYEDQSSPEAKFAKDLDRYDMILQAFEYEN 510
           +EYE  +S  AK  KD D+ +M+LQA EYE+
Sbjct: 127 EEYEAGTSATAKLVKDCDKLEMVLQAQEYES 157


>UniRef50_A3LQW0 Cluster: Predicted protein; n=6;
           Saccharomycetales|Rep: Predicted protein - Pichia
           stipitis (Yeast)
          Length = 223

 Score = 84.6 bits (200), Expect = 2e-15
 Identities = 40/91 (43%), Positives = 66/91 (72%), Gaps = 4/91 (4%)
 Frame = +1

Query: 247 NKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGIAGDR----MYEL 414
           +K ++IAL+HD+AE +VGD+TP  GV+  EKHRRE E+++ +S +     +R    + EL
Sbjct: 85  SKCVKIALVHDIAESLVGDITPFGGVTKAEKHRRELESIQYLSEIIKPYNERFSKEILEL 144

Query: 415 YKEYEDQSSPEAKFAKDLDRYDMILQAFEYE 507
           + +YE+  + EA++ KD+D+Y+MI QA++YE
Sbjct: 145 WLDYEEIRTIEARYVKDIDKYEMIQQAWDYE 175



 Score = 34.3 bits (75), Expect = 2.9
 Identities = 17/39 (43%), Positives = 23/39 (58%), Gaps = 2/39 (5%)
 Frame = +2

Query: 116 KHVKRTGWILCDI--NDCETIAGHMYRMGIMTFLLTEEN 226
           K  KRTGW+   I     E+I+ HMYRM I++  +  EN
Sbjct: 43  KTQKRTGWVDRGIPAEKVESISDHMYRMSIISMFIPNEN 81


>UniRef50_Q4PHJ8 Cluster: Putative uncharacterized protein; n=1;
            Ustilago maydis|Rep: Putative uncharacterized protein -
            Ustilago maydis (Smut fungus)
          Length = 1652

 Score = 83.8 bits (198), Expect = 4e-15
 Identities = 45/89 (50%), Positives = 62/89 (69%), Gaps = 3/89 (3%)
 Frame = +1

Query: 250  KILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMK-TISGLTG--IAGDRMYELYK 420
            K +Q+A++HDLAE  VGDLTP  GV  +EK RRE EA++  +  L G   AG R+  L++
Sbjct: 1510 KCVQLAIVHDLAEAEVGDLTPLDGVDKKEKVRREKEAIQYFVHDLLGSSAAGLRIEALWE 1569

Query: 421  EYEDQSSPEAKFAKDLDRYDMILQAFEYE 507
            EYE + S E++  KDLDR+++ LQA EYE
Sbjct: 1570 EYEARQSKESRLVKDLDRFELGLQAIEYE 1598



 Score = 33.5 bits (73), Expect = 5.0
 Identities = 15/33 (45%), Positives = 20/33 (60%)
 Frame = +2

Query: 125  KRTGWILCDINDCETIAGHMYRMGIMTFLLTEE 223
            KRTGW+   +   E+IA HMYRM ++  L   E
Sbjct: 1471 KRTGWLHHRVAAPESIADHMYRMAMLCLLCPAE 1503


>UniRef50_P38331 Cluster: Uncharacterized protein YBR242W; n=10;
           Saccharomycetales|Rep: Uncharacterized protein YBR242W -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 238

 Score = 83.4 bits (197), Expect = 5e-15
 Identities = 40/95 (42%), Positives = 63/95 (66%), Gaps = 5/95 (5%)
 Frame = +1

Query: 238 IGQNKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMK-----TISGLTGIAGDR 402
           + ++K ++IAL+HD+AE +VGD+TP   +  EEKHRRE E +K      I     IA   
Sbjct: 96  VNRDKCVRIALVHDIAESLVGDITPVDPIGKEEKHRREWETIKYLCNALIKPYNEIAAKE 155

Query: 403 MYELYKEYEDQSSPEAKFAKDLDRYDMILQAFEYE 507
           + + +  YE+ +S EA++ KD+D+Y+M++Q FEYE
Sbjct: 156 IMDDWLAYENVTSLEARYVKDIDKYEMLVQCFEYE 190



 Score = 40.3 bits (90), Expect = 0.044
 Identities = 21/56 (37%), Positives = 32/56 (57%), Gaps = 1/56 (1%)
 Frame = +2

Query: 86  LLFITQYFSKKHVKRTGWILCDINDCETIAGHMYRMGIMTFLLTEEN-NPTKLDRI 250
           L F+      K  +RTG++   I +CE+I+ HMYR+ I+T L+ +   N  K  RI
Sbjct: 49  LAFLNVVQQLKIQRRTGYLDLGIKECESISDHMYRLSIITMLIKDSRVNRDKCVRI 104


>UniRef50_UPI000023F3D1 Cluster: hypothetical protein FG08678.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG08678.1 - Gibberella zeae PH-1
          Length = 221

 Score = 83.0 bits (196), Expect = 6e-15
 Identities = 39/91 (42%), Positives = 63/91 (69%), Gaps = 1/91 (1%)
 Frame = +1

Query: 238 IGQNKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISG-LTGIAGDRMYEL 414
           + Q K +++ L+HD+AE +VGD+TP  GVS +EK RRE   ++ I+   +G     + EL
Sbjct: 63  LNQVKCMKMCLVHDIAESVVGDITPFSGVSRDEKGRREAATIEYIANRWSGPYTAEIKEL 122

Query: 415 YKEYEDQSSPEAKFAKDLDRYDMILQAFEYE 507
           + E+E   SPEA+F++D+D+ +++LQA EYE
Sbjct: 123 WDEFEAAESPEAQFSQDIDKIELLLQAVEYE 153


>UniRef50_A0DPT1 Cluster: Chromosome undetermined scaffold_59, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_59,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 182

 Score = 80.6 bits (190), Expect = 3e-14
 Identities = 37/91 (40%), Positives = 61/91 (67%), Gaps = 1/91 (1%)
 Frame = +1

Query: 238 IGQNKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMK-TISGLTGIAGDRMYEL 414
           + ++K ++IAL+HDLAE IVGD+ P   +   EK ++ED AM+  +  L     + +Y +
Sbjct: 53  LNKDKCIKIALLHDLAEVIVGDIIPSENMPANEKKQKEDNAMRMMVQDLDEDIKNELYSI 112

Query: 415 YKEYEDQSSPEAKFAKDLDRYDMILQAFEYE 507
           +KEYE+  S EA+  ++LD+ +M+ QAF+YE
Sbjct: 113 HKEYENGESIEAEVVRELDKLEMLFQAFDYE 143


>UniRef50_Q6CED3 Cluster: Similar to sp|P38331 Saccharomyces
           cerevisiae YBR242w; n=1; Yarrowia lipolytica|Rep:
           Similar to sp|P38331 Saccharomyces cerevisiae YBR242w -
           Yarrowia lipolytica (Candida lipolytica)
          Length = 242

 Score = 79.0 bits (186), Expect = 1e-13
 Identities = 35/94 (37%), Positives = 63/94 (67%), Gaps = 4/94 (4%)
 Frame = +1

Query: 238 IGQNKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGL----TGIAGDRM 405
           + QN  +++AL+HD+AE IVGD+TP   ++  EK RRE  ++  ++ L      +A   +
Sbjct: 102 VNQNTCVKMALVHDMAEAIVGDITPFDDMTKAEKSRREHSSIIYMAALVEKYNPVAAKEI 161

Query: 406 YELYKEYEDQSSPEAKFAKDLDRYDMILQAFEYE 507
            +L+ +YE+ S+ EA+  KD+D+++++LQ +EYE
Sbjct: 162 VDLWNQYENCSTDEARLVKDIDKFELMLQTYEYE 195


>UniRef50_Q55UE1 Cluster: Putative uncharacterized protein; n=2;
           Filobasidiella neoformans|Rep: Putative uncharacterized
           protein - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 259

 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 41/98 (41%), Positives = 62/98 (63%), Gaps = 6/98 (6%)
 Frame = +1

Query: 250 KILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKT-ISGLTGIAG-----DRMYE 411
           + + +AL+HDLAE  VGD+TP  GV    KH+ E++AM T ++ + G  G     +R   
Sbjct: 114 RCVMMALVHDLAEAYVGDITPVEGVPTHVKHQLEEQAMDTFLNEMLGGKGNKDARERFRS 173

Query: 412 LYKEYEDQSSPEAKFAKDLDRYDMILQAFEYENVKILQ 525
           L+ EYE + +PE++  KDLDR ++ LQA EYE  + +Q
Sbjct: 174 LWDEYEARETPESRLVKDLDRIELALQAVEYERSQDIQ 211



 Score = 34.7 bits (76), Expect = 2.2
 Identities = 17/49 (34%), Positives = 26/49 (53%)
 Frame = +2

Query: 68  SESRIKLLFITQYFSKKHVKRTGWILCDINDCETIAGHMYRMGIMTFLL 214
           +E+   L F+      K  KR+GWI   +   E+I+ HM RM +M  +L
Sbjct: 54  NEALDTLAFLHMLEQLKIQKRSGWIREGVKQAESISDHMCRMALMAMML 102


>UniRef50_Q0U692 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 252

 Score = 75.8 bits (178), Expect = 1e-12
 Identities = 40/101 (39%), Positives = 61/101 (60%), Gaps = 6/101 (5%)
 Frame = +1

Query: 250 KILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLT------GIAGDRMYE 411
           K  ++ALIHD+AE +VGD+TP   VS EEK RRE E M  I          G+ G  + +
Sbjct: 105 KCCRMALIHDMAEALVGDITPVDPVSKEEKSRRESETMDYICEKLLGKVGGGLNGVEVRK 164

Query: 412 LYKEYEDQSSPEAKFAKDLDRYDMILQAFEYENVKILQRNV 534
           +++EYED  + E+ F  D+D+ +++LQ  EYE     +R++
Sbjct: 165 IWQEYEDSETSESLFVHDVDKIELLLQMVEYERESGCERDL 205



 Score = 35.5 bits (78), Expect = 1.2
 Identities = 20/46 (43%), Positives = 26/46 (56%)
 Frame = +2

Query: 116 KHVKRTGWILCDINDCETIAGHMYRMGIMTFLLTEENNPTKLDRIK 253
           K  KR GW    I   E+I+ HMYRM I+T +L   +  +KLD  K
Sbjct: 61  KTTKRAGWQRFGIPAPESISDHMYRMSIIT-MLAPASLSSKLDMAK 105


>UniRef50_UPI00004988B4 Cluster: metal dependent phosphohydrolase;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: metal
           dependent phosphohydrolase - Entamoeba histolytica
           HM-1:IMSS
          Length = 179

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 34/91 (37%), Positives = 59/91 (64%), Gaps = 1/91 (1%)
 Frame = +1

Query: 238 IGQNKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISG-LTGIAGDRMYEL 414
           + +N  + ++L HD+AE ++GD+TP+  V+PEEKH+RE  A+  +S  L    G+ +   
Sbjct: 52  LDRNHAIMVSLCHDMAEALIGDITPNDPVTPEEKHKRELNAITEMSKLLPNEIGEEIKNC 111

Query: 415 YKEYEDQSSPEAKFAKDLDRYDMILQAFEYE 507
           + E+E++ +  A+F   LD+ +M +QA EYE
Sbjct: 112 WIEFEEKKTEVAQFCAQLDKIEMCIQADEYE 142



 Score = 41.5 bits (93), Expect = 0.019
 Identities = 18/44 (40%), Positives = 28/44 (63%)
 Frame = +2

Query: 116 KHVKRTGWILCDINDCETIAGHMYRMGIMTFLLTEENNPTKLDR 247
           KH+ RTGW+  ++ + E+I+ HMYRM I+  +      P+ LDR
Sbjct: 15  KHIPRTGWVYNNVPNPESISDHMYRMAILAMIFC----PSHLDR 54


>UniRef50_Q08WG0 Cluster: Metal-dependent phosphohydrolase, HD
           superfamily; n=1; Stigmatella aurantiaca DW4/3-1|Rep:
           Metal-dependent phosphohydrolase, HD superfamily -
           Stigmatella aurantiaca DW4/3-1
          Length = 199

 Score = 72.9 bits (171), Expect = 7e-12
 Identities = 39/87 (44%), Positives = 53/87 (60%)
 Frame = +1

Query: 250 KILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGIAGDRMYELYKEYE 429
           K+++IAL+HDL E  VGD+TPH GV   +KH  E  A++ I G     G     L+ EYE
Sbjct: 77  KVVRIALLHDLGEARVGDITPHDGVDHAQKHALERRAVEQILGKLP-RGAEYLALWDEYE 135

Query: 430 DQSSPEAKFAKDLDRYDMILQAFEYEN 510
             SS EA+  + +DR +M LQA  YE+
Sbjct: 136 QGSSFEARLVRQVDRLEMGLQACVYEH 162


>UniRef50_Q4X103 Cluster: HD family hydrolase, putative; n=12;
           Pezizomycotina|Rep: HD family hydrolase, putative -
           Aspergillus fumigatus (Sartorya fumigata)
          Length = 226

 Score = 72.5 bits (170), Expect = 9e-12
 Identities = 38/91 (41%), Positives = 59/91 (64%), Gaps = 7/91 (7%)
 Frame = +1

Query: 256 LQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTIS-----GLTG--IAGDRMYEL 414
           +++ALIHD+AE IVGD+TP   V+  EK RRE E M  I+     G+ G  + G+ + ++
Sbjct: 88  MKMALIHDMAESIVGDITPVDKVNKAEKARREAEVMDYIAKNLLGGVPGGMLTGEEILKV 147

Query: 415 YKEYEDQSSPEAKFAKDLDRYDMILQAFEYE 507
           + EYE   + EA+F  D+D+ +++LQ  EYE
Sbjct: 148 FNEYEANETLEAQFVHDVDKMELLLQMLEYE 178



 Score = 36.3 bits (80), Expect = 0.71
 Identities = 17/32 (53%), Positives = 20/32 (62%)
 Frame = +2

Query: 116 KHVKRTGWILCDINDCETIAGHMYRMGIMTFL 211
           K  KR GW    I+  E+I+ HMYRM IMT L
Sbjct: 42  KTTKREGWRRFGISTGESISDHMYRMSIMTML 73


>UniRef50_A4RGR2 Cluster: Putative uncharacterized protein; n=2;
           Pezizomycotina|Rep: Putative uncharacterized protein -
           Magnaporthe grisea (Rice blast fungus) (Pyricularia
           grisea)
          Length = 251

 Score = 72.5 bits (170), Expect = 9e-12
 Identities = 40/95 (42%), Positives = 57/95 (60%), Gaps = 8/95 (8%)
 Frame = +1

Query: 247 NKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTI-SGLTG-------IAGDR 402
           NK +++ LIHD+AE +VGD+TP  GV+  EK RRE   M  I S L G         G  
Sbjct: 84  NKCIKMCLIHDMAESLVGDITPVDGVAKPEKARREAATMDYITSTLLGNVYGGGNTVGAE 143

Query: 403 MYELYKEYEDQSSPEAKFAKDLDRYDMILQAFEYE 507
           M  +++EYED  + E+K+  D+D+ ++I Q  EYE
Sbjct: 144 MRAIWQEYEDSETLESKYVHDIDKMELICQMVEYE 178


>UniRef50_Q8LQ52 Cluster: Metal-dependent phosphohydrolase HD
           domain-containing protein-like; n=7; Magnoliophyta|Rep:
           Metal-dependent phosphohydrolase HD domain-containing
           protein-like - Oryza sativa subsp. japonica (Rice)
          Length = 461

 Score = 70.9 bits (166), Expect = 3e-11
 Identities = 33/81 (40%), Positives = 52/81 (64%), Gaps = 2/81 (2%)
 Frame = +1

Query: 238 IGQNKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLT--GIAGDRMYE 411
           + + + ++IA++HD+AE IVGD+TP  G+   EK RRE +A+  +  +   G   D + E
Sbjct: 214 VDRERCIKIAIVHDIAEAIVGDITPSDGIPKAEKSRREQKALNEMCEVLGGGPIADEIKE 273

Query: 412 LYKEYEDQSSPEAKFAKDLDR 474
           L++EYE+ SS EA   KD D+
Sbjct: 274 LWEEYENNSSIEANLVKDFDK 294



 Score = 37.9 bits (84), Expect = 0.23
 Identities = 18/40 (45%), Positives = 22/40 (55%)
 Frame = +2

Query: 92  FITQYFSKKHVKRTGWILCDINDCETIAGHMYRMGIMTFL 211
           F+T     K  KR GWI   I   E+IA HMYRM +M  +
Sbjct: 168 FLTLCHRLKTTKRKGWINHSIKGPESIADHMYRMALMALI 207


>UniRef50_A4IBV0 Cluster: Putative uncharacterized protein; n=5;
           Trypanosomatidae|Rep: Putative uncharacterized protein -
           Leishmania infantum
          Length = 206

 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 31/97 (31%), Positives = 60/97 (61%), Gaps = 5/97 (5%)
 Frame = +1

Query: 238 IGQNKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGIAGDRMY--- 408
           + +++++++AL HD  E I+GD++P   V  E K ++E +A++ +  L   +    +   
Sbjct: 61  LNRDRMIKMALCHDTGESIIGDISPAMKVPKEVKKQQESQAVQDLCNLVSSSPSTTFSKE 120

Query: 409 --ELYKEYEDQSSPEAKFAKDLDRYDMILQAFEYENV 513
             +L++EYE Q + E+ F KD+D  +M++QA  YE+V
Sbjct: 121 LGDLFEEYEAQETAESHFVKDMDLLEMVVQAHSYESV 157


>UniRef50_Q3IT40 Cluster: Putative uncharacterized protein; n=1;
           Natronomonas pharaonis DSM 2160|Rep: Putative
           uncharacterized protein - Natronomonas pharaonis (strain
           DSM 2160 / ATCC 35678)
          Length = 198

 Score = 66.9 bits (156), Expect = 4e-10
 Identities = 39/95 (41%), Positives = 55/95 (57%), Gaps = 5/95 (5%)
 Frame = +1

Query: 238 IGQNKILQIALIHDLAECIVGDLTPHCG-----VSPEEKHRREDEAMKTISGLTGIAGDR 402
           + + + L +A++HD+AE  VGD+          V  EEK RRE  A+     L G+ GD 
Sbjct: 56  LDRERALSLAVVHDIAEAEVGDIPTRADPDADTVDDEEKVRRERAALS--GPLAGL-GDD 112

Query: 403 MYELYKEYEDQSSPEAKFAKDLDRYDMILQAFEYE 507
           + EL++ YE + SPEA+F KD+D  D  LQA  YE
Sbjct: 113 IRELWEAYERRDSPEARFVKDMDLLDTCLQALVYE 147


>UniRef50_Q9UY89 Cluster: Metal-dependent phosphohydrolase,
           putative; n=2; Pyrococcus|Rep: Metal-dependent
           phosphohydrolase, putative - Pyrococcus abyssi
          Length = 179

 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 34/90 (37%), Positives = 55/90 (61%)
 Frame = +1

Query: 238 IGQNKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGIAGDRMYELY 417
           I +N++L++A+IHD+ E ++ D+ P       +K   ED+A+K I           YELY
Sbjct: 58  IDENRVLKMAIIHDIGEALITDI-PLRAQKYLDKDAAEDKAVKEIF-------PEFYELY 109

Query: 418 KEYEDQSSPEAKFAKDLDRYDMILQAFEYE 507
           +EY++  S EA+  K  D+ DM+LQA++YE
Sbjct: 110 REYQEGKSLEAQLVKFADKIDMVLQAWQYE 139


>UniRef50_Q9Y3D1 Cluster: CGI-130 protein; n=4; Eutheria|Rep:
           CGI-130 protein - Homo sapiens (Human)
          Length = 170

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 31/66 (46%), Positives = 45/66 (68%), Gaps = 1/66 (1%)
 Frame = +1

Query: 322 VSPEEKHRREDEAMKTISGLTGI-AGDRMYELYKEYEDQSSPEAKFAKDLDRYDMILQAF 498
           V  +++  ++ EAMK I+ L        +YEL++EYE QSS EAKF K LD+ +MILQA 
Sbjct: 59  VIKDDRLNKDPEAMKQITQLLPEDLRKELYELWEEYETQSSAEAKFVKQLDQCEMILQAS 118

Query: 499 EYENVK 516
           EYE+++
Sbjct: 119 EYEDLE 124



 Score = 39.9 bits (89), Expect = 0.058
 Identities = 16/50 (32%), Positives = 29/50 (58%)
 Frame = +2

Query: 74  SRIKLLFITQYFSKKHVKRTGWILCDINDCETIAGHMYRMGIMTFLLTEE 223
           +R  L F+      K V RTGW+  ++   E+++ HMYRM +M  ++ ++
Sbjct: 14  ARSLLQFLRLVGQLKRVPRTGWVYRNVQRPESVSDHMYRMAVMAMVIKDD 63



 Score = 37.9 bits (84), Expect = 0.23
 Identities = 16/34 (47%), Positives = 23/34 (67%)
 Frame = +3

Query: 513 ENTPKKCQEFFTATEGKFDHPFIQDLVKELYLQR 614
           E+ P + Q+F+ +T GKF+HP I  LV EL  +R
Sbjct: 124 EHKPGRLQDFYDSTAGKFNHPEIVQLVSELEAER 157


>UniRef50_Q7R6E7 Cluster: GLP_574_17393_16761; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_574_17393_16761 - Giardia lamblia
           ATCC 50803
          Length = 210

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 39/94 (41%), Positives = 54/94 (57%), Gaps = 7/94 (7%)
 Frame = +1

Query: 244 QNKILQIALIHDLAECIVGDLTPHC--GVSPEEKHRREDEAMKTISGLTGIAG-DRMYEL 414
           + +++ + L+HDLAE IVGD+ P     VS  EK  +E  AM+ +  L   +G  RM  L
Sbjct: 62  RTRLVCMMLLHDLAESIVGDIIPESLSKVSAAEKRMQEASAMRELVLLLCNSGLHRMGAL 121

Query: 415 YKE----YEDQSSPEAKFAKDLDRYDMILQAFEY 504
           YKE    YED  SP A+ A  +D+ DM+ QA  Y
Sbjct: 122 YKELFTMYEDAHSPLARAAHVIDKIDMLCQAHCY 155


>UniRef50_A5UYG9 Cluster: Metal dependent phosphohydrolase; n=2;
           Roseiflexus|Rep: Metal dependent phosphohydrolase -
           Roseiflexus sp. RS-1
          Length = 186

 Score = 57.6 bits (133), Expect = 3e-07
 Identities = 30/91 (32%), Positives = 51/91 (56%), Gaps = 1/91 (1%)
 Frame = +1

Query: 238 IGQNKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGI-AGDRMYEL 414
           + + ++L +AL+HD+AE ++GDL         E  +R+ E    +   T I  GD +  L
Sbjct: 59  VDRERVLAMALVHDIAEALIGDLPFSARRLIGEAVKRDAERRALVELCTPIPGGDHLIRL 118

Query: 415 YKEYEDQSSPEAKFAKDLDRYDMILQAFEYE 507
           ++EY   ++ EA+  K LDR + ++QA  YE
Sbjct: 119 WEEYAAGATREARLVKALDRVETLVQALAYE 149


>UniRef50_O52019 Cluster: Putative uncharacterized protein; n=1;
           Halobacterium salinarum|Rep: Putative uncharacterized
           protein - Halobacterium salinarium (Halobacterium
           halobium)
          Length = 203

 Score = 56.0 bits (129), Expect = 8e-07
 Identities = 31/93 (33%), Positives = 47/93 (50%), Gaps = 3/93 (3%)
 Frame = +1

Query: 238 IGQNKILQIALIHDLAECIVGDLTPHC--GVSPEEKHRREDEAMKTISGLTGIAGD-RMY 408
           + + K + +ALIHDL E   GD+      G        +E      ++ L G   D  + 
Sbjct: 54  VDRQKAVTMALIHDLGEARTGDIATRAEDGRQTIPTSEKETAERSAVTDLVGPFNDSELL 113

Query: 409 ELYKEYEDQSSPEAKFAKDLDRYDMILQAFEYE 507
            L++EYE + +P A+F KD+D  D  LQA +YE
Sbjct: 114 SLWEEYEARDTPTAQFVKDMDLVDNCLQALKYE 146


>UniRef50_Q3DW72 Cluster: Metal-dependent phosphohydrolase, HD
           subdomain; n=2; Chloroflexus|Rep: Metal-dependent
           phosphohydrolase, HD subdomain - Chloroflexus
           aurantiacus J-10-fl
          Length = 197

 Score = 54.4 bits (125), Expect = 3e-06
 Identities = 31/92 (33%), Positives = 49/92 (53%), Gaps = 2/92 (2%)
 Frame = +1

Query: 238 IGQNKILQIALIHDLAECIVGDLTPHCG--VSPEEKHRREDEAMKTISGLTGIAGDRMYE 411
           I + ++L IAL+HDLAE ++ DL       +  E K + E + +  + G      D    
Sbjct: 67  IDRGRLLAIALLHDLAESLLSDLPASATRLLGKEAKRQAERDGLAALIGHLS-RSDEYLT 125

Query: 412 LYKEYEDQSSPEAKFAKDLDRYDMILQAFEYE 507
           L+ EY D +S EA+  K +DR +++ QA  YE
Sbjct: 126 LWDEYVDGTSREARLVKAVDRLELMAQALAYE 157


>UniRef50_A7DMD6 Cluster: Metal dependent phosphohydrolase; n=1;
           Candidatus Nitrosopumilus maritimus SCM1|Rep: Metal
           dependent phosphohydrolase - Candidatus Nitrosopumilus
           maritimus SCM1
          Length = 177

 Score = 54.4 bits (125), Expect = 3e-06
 Identities = 30/92 (32%), Positives = 51/92 (55%), Gaps = 1/92 (1%)
 Frame = +1

Query: 238 IGQNKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAM-KTISGLTGIAGDRMYEL 414
           +   KIL++ L+HDLAE  +GD+ P   +S EEK + E+ A  + I  L         E+
Sbjct: 52  LNSEKILKMILLHDLAESKIGDIVPD-KMSLEEKQKLENSAFDEIIKTLPESLTHNYVEI 110

Query: 415 YKEYEDQSSPEAKFAKDLDRYDMILQAFEYEN 510
           + EY+  ++ E+     +D+ +M LQA  Y++
Sbjct: 111 WNEYQKNNTDESSIVHQVDKLEMALQAKIYQS 142


>UniRef50_Q192N4 Cluster: HD domain protein; n=2; Desulfitobacterium
           hafniense|Rep: HD domain protein - Desulfitobacterium
           hafniense (strain DCB-2)
          Length = 197

 Score = 53.2 bits (122), Expect = 6e-06
 Identities = 30/87 (34%), Positives = 45/87 (51%), Gaps = 1/87 (1%)
 Frame = +1

Query: 250 KILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAM-KTISGLTGIAGDRMYELYKEY 426
           K++ + LIHDL E   GD   +     E+K  RE EA  +  + L      RM  L++E+
Sbjct: 64  KVISMVLIHDLVEIYAGDTYCYDEKGYEDKAEREQEAADRLFNMLPEDQAQRMMSLWQEF 123

Query: 427 EDQSSPEAKFAKDLDRYDMILQAFEYE 507
           E+  + EA FA  LDR+  +L  +  E
Sbjct: 124 EEMETKEAAFAATLDRFQPLLLNYNTE 150


>UniRef50_Q8TZ99 Cluster: Predicted hydrolase of the HD superfamily;
           n=1; Methanopyrus kandleri|Rep: Predicted hydrolase of
           the HD superfamily - Methanopyrus kandleri
          Length = 188

 Score = 53.2 bits (122), Expect = 6e-06
 Identities = 33/89 (37%), Positives = 48/89 (53%), Gaps = 1/89 (1%)
 Frame = +1

Query: 250 KILQIALIHDLAECIVGDLTPHCG-VSPEEKHRREDEAMKTISGLTGIAGDRMYELYKEY 426
           K + +ALIHDL E +  DL      V  + K   E++A + +        + + +L++E+
Sbjct: 59  KTVVMALIHDLPEALTLDLDVEASRVFGDAKREAEEKAAECVFD------EELLDLWREF 112

Query: 427 EDQSSPEAKFAKDLDRYDMILQAFEYENV 513
           E + SPEAK AK  D  DM LQA EY  V
Sbjct: 113 ERRESPEAKAAKLADTLDMALQALEYSQV 141


>UniRef50_Q0W115 Cluster: Predicted metal-dependent
           phosphohydrolase; n=1; uncultured methanogenic archaeon
           RC-I|Rep: Predicted metal-dependent phosphohydrolase -
           Uncultured methanogenic archaeon RC-I
          Length = 196

 Score = 53.2 bits (122), Expect = 6e-06
 Identities = 30/84 (35%), Positives = 47/84 (55%), Gaps = 1/84 (1%)
 Frame = +1

Query: 250 KILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGIAGDRMYE-LYKEY 426
           K +++ALIHD+ E  VGD+  +      EK  RE EA K + GL        Y  L++E+
Sbjct: 63  KAVKMALIHDVVEVDVGDIFVYDQERMAEKEAREKEAAKRLFGLLPPDQAEEYRALWEEF 122

Query: 427 EDQSSPEAKFAKDLDRYDMILQAF 498
           E + +PEA++A  +DR   +L  +
Sbjct: 123 EARETPEARYAAAIDRLQPVLHNY 146


>UniRef50_A7D845 Cluster: Metal-dependent phosphohydrolase, HD sub
           domain; n=1; Halorubrum lacusprofundi ATCC 49239|Rep:
           Metal-dependent phosphohydrolase, HD sub domain -
           Halorubrum lacusprofundi ATCC 49239
          Length = 219

 Score = 53.2 bits (122), Expect = 6e-06
 Identities = 28/89 (31%), Positives = 47/89 (52%), Gaps = 2/89 (2%)
 Frame = +1

Query: 247 NKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMK--TISGLTGIAGDRMYELYK 420
           ++ L++A++HD+AE   GD       + +       EA +   +  L G   DR+ + ++
Sbjct: 76  DRALRLAVVHDVAEAETGDAATRADSTADSVDAAAKEAAERAAMEDLAGALPDRIRDAWE 135

Query: 421 EYEDQSSPEAKFAKDLDRYDMILQAFEYE 507
           +YE + SPEA   K+ D  D+ LQA  YE
Sbjct: 136 DYEARESPEAILVKECDLLDVCLQAVLYE 164


>UniRef50_A6PNY3 Cluster: Metal dependent phosphohydrolase; n=1;
           Victivallis vadensis ATCC BAA-548|Rep: Metal dependent
           phosphohydrolase - Victivallis vadensis ATCC BAA-548
          Length = 188

 Score = 52.8 bits (121), Expect = 8e-06
 Identities = 28/82 (34%), Positives = 45/82 (54%), Gaps = 1/82 (1%)
 Frame = +1

Query: 250 KILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTI-SGLTGIAGDRMYELYKEY 426
           ++L + LIHDL E   GD++        EK+  E +A + I S L       + +L++EY
Sbjct: 59  RVLMMCLIHDLGELYTGDVSAALEPDAAEKYEEEHQAARRIFSLLPESQAAELLQLWREY 118

Query: 427 EDQSSPEAKFAKDLDRYDMILQ 492
               +PEA+F K LD+ + I+Q
Sbjct: 119 GAGETPEARFVKALDKAETIIQ 140


>UniRef50_A6D2I3 Cluster: Putative uncharacterized protein; n=2;
           Vibrionaceae|Rep: Putative uncharacterized protein -
           Vibrio shilonii AK1
          Length = 195

 Score = 52.8 bits (121), Expect = 8e-06
 Identities = 30/103 (29%), Positives = 54/103 (52%), Gaps = 1/103 (0%)
 Frame = +1

Query: 250 KILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISG-LTGIAGDRMYELYKEY 426
           K++++ L+HD+ E   GD   +   + E + + E EA K + G L    G+ ++ ++ E+
Sbjct: 62  KVVKMLLLHDMVEIDAGDTFVYDTAAYETQQQTELEAAKRLFGMLPDDQGEALFSVWCEF 121

Query: 427 EDQSSPEAKFAKDLDRYDMILQAFEYENVKILQRNVKSSLLQQ 555
           E   S EA+FAK LDR   +L  +  +    ++ NV    + Q
Sbjct: 122 EAAESAEARFAKALDRLIPMLLNYHNDGQSWIENNVSKQQVMQ 164


>UniRef50_Q399M0 Cluster: Metal-dependent phosphohydrolase; n=18;
           Proteobacteria|Rep: Metal-dependent phosphohydrolase -
           Burkholderia sp. (strain 383) (Burkholderia cepacia
           (strain ATCC 17760/ NCIB 9086 / R18194))
          Length = 193

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 25/82 (30%), Positives = 45/82 (54%), Gaps = 1/82 (1%)
 Frame = +1

Query: 250 KILQIALIHDLAECIVGDLTP-HCGVSPEEKHRREDEAMKTISGLTGIAGDRMYELYKEY 426
           K+L++ ++HDL E + GD+        P++  +  D+ +   + L     D +  L+ EY
Sbjct: 61  KLLKLCVVHDLGEALHGDIPAIEQAAHPDKSAQERDDLLTLTAPLAPAQRDEIVALWDEY 120

Query: 427 EDQSSPEAKFAKDLDRYDMILQ 492
           E  ++PEA+ AK  D+ + ILQ
Sbjct: 121 EAAATPEARAAKAFDKLETILQ 142


>UniRef50_Q1MS33 Cluster: Putative uncharacterized protein LI0136;
           n=1; Lawsonia intracellularis PHE/MN1-00|Rep: Putative
           uncharacterized protein LI0136 - Lawsonia
           intracellularis (strain PHE/MN1-00)
          Length = 215

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 29/89 (32%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
 Frame = +1

Query: 247 NKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAM-KTISGLTGIAGDRMYELYKE 423
           NK+L++A++HDL E + GD+        ++K   E   M +  +GL       M  L+ E
Sbjct: 75  NKLLRLAVVHDLGEAVCGDIPAIAKPDLDKKSETERRGMCELCTGLPESIYTEMLALWDE 134

Query: 424 YEDQSSPEAKFAKDLDRYDMILQAFEYEN 510
           YE   + EAK  K LD+ + I+Q  + +N
Sbjct: 135 YELAETLEAKIVKGLDKLETIMQHNQGKN 163


>UniRef50_Q8U3R1 Cluster: Oxetanocin-like protein; n=2;
           Thermococcaceae|Rep: Oxetanocin-like protein -
           Pyrococcus furiosus
          Length = 176

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 33/90 (36%), Positives = 46/90 (51%)
 Frame = +1

Query: 238 IGQNKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGIAGDRMYELY 417
           I   K L+IA+IHDL E I+ DL P        K   E +A+K +            EL+
Sbjct: 55  IDVEKALKIAIIHDLGEAIITDL-PLSAQKYLNKEEAEAKALKDVL-------PEYTELF 106

Query: 418 KEYEDQSSPEAKFAKDLDRYDMILQAFEYE 507
           +EY    + E +  K  D+ DMI+QA+EYE
Sbjct: 107 EEYSKALTLEGQLVKIADKLDMIIQAYEYE 136



 Score = 37.5 bits (83), Expect = 0.31
 Identities = 14/36 (38%), Positives = 23/36 (63%)
 Frame = +2

Query: 116 KHVKRTGWILCDINDCETIAGHMYRMGIMTFLLTEE 223
           K + R GW++  + + E++A H YR+  +T LL EE
Sbjct: 12  KRIPRMGWLIKGVPNPESVADHSYRVAFITLLLAEE 47


>UniRef50_A0RU59 Cluster: HD superfamily hydrolase; n=2;
           Thermoprotei|Rep: HD superfamily hydrolase - Cenarchaeum
           symbiosum
          Length = 268

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 26/87 (29%), Positives = 50/87 (57%), Gaps = 1/87 (1%)
 Frame = +1

Query: 247 NKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTI-SGLTGIAGDRMYELYKE 423
           +K+++++L+HDLAE +  D+TP   +   +K   E++ M  I S L     +R   ++ E
Sbjct: 55  DKMVRMSLLHDLAETVTSDITPE-KMEGHDKQELENKVMLGILSTLPAALQERYLGIWDE 113

Query: 424 YEDQSSPEAKFAKDLDRYDMILQAFEY 504
           +    SPE++   ++D+ +M +QA  Y
Sbjct: 114 FSAGKSPESRLFHEIDKLEMAIQATAY 140


>UniRef50_Q7N1B9 Cluster: Similar to unknown protein; n=7;
           Enterobacteriaceae|Rep: Similar to unknown protein -
           Photorhabdus luminescens subsp. laumondii
          Length = 201

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 31/112 (27%), Positives = 53/112 (47%), Gaps = 1/112 (0%)
 Frame = +1

Query: 250 KILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISG-LTGIAGDRMYELYKEY 426
           +++Q+ALIHD+ E   GD+  +   + E  H +E +A   + G L     +    L++EY
Sbjct: 69  RVIQMALIHDIVEIDAGDVMVYDLTAREAIHEQEVKAANRLFGLLPEPQKNHFMSLWQEY 128

Query: 427 EDQSSPEAKFAKDLDRYDMILQAFEYENVKILQRNVKSSLLQQRENLTTRLY 582
           E   S +A+FA  LDR   IL     +    ++ N++   +  R       Y
Sbjct: 129 EAGESQDARFAITLDRLMPILMNLHNKGQSWVENNIRFEQVINRNKFIANTY 180


>UniRef50_Q3EUQ7 Cluster: Hydrolase; n=12; Bacillus|Rep: Hydrolase -
           Bacillus thuringiensis serovar israelensis ATCC 35646
          Length = 205

 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 29/86 (33%), Positives = 49/86 (56%), Gaps = 5/86 (5%)
 Frame = +1

Query: 250 KILQIALIHDLAECIVGDLTPHCGVSPEE----KHRREDEAMKTISG-LTGIAGDRMYEL 414
           K+L++ +IHDL E   GD+     ++  E    K + E EA+  I   LT   G+ +Y+L
Sbjct: 63  KLLKMVIIHDLVEAEAGDIPAFDTMNSHELQLQKQKNELEAILNIKQTLTSSLGEELYDL 122

Query: 415 YKEYEDQSSPEAKFAKDLDRYDMILQ 492
           + E+E + + EAK A  LD+ ++ +Q
Sbjct: 123 WMEFEAKETYEAKVANALDKLEVKIQ 148


>UniRef50_Q0FP87 Cluster: HD domain protein; n=10;
           Proteobacteria|Rep: HD domain protein - Roseovarius sp.
           HTCC2601
          Length = 197

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 27/81 (33%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
 Frame = +1

Query: 238 IGQNKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGIA-GDRMYEL 414
           I   +++++ LIHDL E   GD+     V    K   E  A + + G+   A G  +  L
Sbjct: 63  ISVERVIRMLLIHDLVEIDAGDVPFFGEVDEAAKTAEETAAAERLFGMLPQAQGADLLAL 122

Query: 415 YKEYEDQSSPEAKFAKDLDRY 477
           + E+E   +P+A+FAK LDR+
Sbjct: 123 WHEFEANETPDARFAKSLDRF 143


>UniRef50_Q62CP8 Cluster: HD domain protein; n=18;
           Proteobacteria|Rep: HD domain protein - Burkholderia
           mallei (Pseudomonas mallei)
          Length = 234

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 29/88 (32%), Positives = 47/88 (53%), Gaps = 1/88 (1%)
 Frame = +1

Query: 250 KILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISG-LTGIAGDRMYELYKEY 426
           K+L++ +IHDL E + GD+      +  +K   E   + T++  L     D +  L+ EY
Sbjct: 99  KVLKMCVIHDLGEALRGDVPAIRADAHPDKSAHERADLLTLTRMLDAPLRDEILSLWDEY 158

Query: 427 EDQSSPEAKFAKDLDRYDMILQAFEYEN 510
           E  +S EA+  K LD+ + ILQ  + EN
Sbjct: 159 ERAASQEAQAVKALDKLETILQHAQGEN 186


>UniRef50_Q099G6 Cluster: Metal-dependent phosphohydrolase, HD
           subdomain; n=3; Proteobacteria|Rep: Metal-dependent
           phosphohydrolase, HD subdomain - Stigmatella aurantiaca
           DW4/3-1
          Length = 204

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 26/76 (34%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
 Frame = +1

Query: 250 KILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISG-LTGIAGDRMYELYKEY 426
           +++ + L+HD+ E   GD   +     EE+   E  A+K I G L G  G     L++E+
Sbjct: 70  RVISMLLVHDIGEIDTGDTLVYAEGGWEERKAAELAAVKRIFGLLPGPQGAAFLALWQEF 129

Query: 427 EDQSSPEAKFAKDLDR 474
           E   +PEA+FA+ +DR
Sbjct: 130 ERGDTPEARFAQAVDR 145


>UniRef50_Q9Y9C8 Cluster: Putative uncharacterized protein; n=1;
           Aeropyrum pernix|Rep: Putative uncharacterized protein -
           Aeropyrum pernix
          Length = 185

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 26/71 (36%), Positives = 45/71 (63%)
 Frame = +1

Query: 250 KILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGIAGDRMYELYKEYE 429
           K + IAL HD+AE ++GD++   G+S   + +RE EA +  + L     + +  L++E+E
Sbjct: 61  KAVAIALYHDMAESVIGDISKRAGLS---RAKREAEA-RAFASLP--LSEGVKNLFREFE 114

Query: 430 DQSSPEAKFAK 462
           + SSPEA+ A+
Sbjct: 115 EASSPEARIAR 125


>UniRef50_Q73R17 Cluster: HD domain protein; n=1; Treponema
           denticola|Rep: HD domain protein - Treponema denticola
          Length = 208

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 28/96 (29%), Positives = 49/96 (51%), Gaps = 1/96 (1%)
 Frame = +1

Query: 250 KILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGIAGDRMY-ELYKEY 426
           K++ + LIHD+ E   GD   +     +E +  E +A   I GL      + +  L++E+
Sbjct: 76  KVISMLLIHDIVEIDAGDTFLYSS-QRDESYNNEKKAADRIFGLLEPDQKKYFLSLWEEF 134

Query: 427 EDQSSPEAKFAKDLDRYDMILQAFEYENVKILQRNV 534
           E++ + EAKFA   DR + I+Q +  E     + N+
Sbjct: 135 EERKTNEAKFASVFDRLEPIIQNYMSEGYSWKKNNI 170


>UniRef50_A6XS73 Cluster: Metal-dependent phosphohydrolase, HD
           subdomain; n=1; Vibrio cholerae AM-19226|Rep:
           Metal-dependent phosphohydrolase, HD subdomain - Vibrio
           cholerae AM-19226
          Length = 183

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 25/80 (31%), Positives = 39/80 (48%)
 Frame = +1

Query: 250 KILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGIAGDRMYELYKEYE 429
           +++++ LIHDL E   GD   +   + E K        K    L   + +    L+ E+E
Sbjct: 51  RVMKMLLIHDLGEIEAGDTVIYSAETEENKQLERSCIQKLFQLLPEASREEFSNLWDEFE 110

Query: 430 DQSSPEAKFAKDLDRYDMIL 489
           +  SPEA FAK +DR   +L
Sbjct: 111 EGVSPEASFAKAIDRVPPLL 130


>UniRef50_Q6LQV5 Cluster: Putative uncharacterized protein BA1657;
           n=8; Gammaproteobacteria|Rep: Putative uncharacterized
           protein BA1657 - Photobacterium profundum
           (Photobacterium sp. (strain SS9))
          Length = 193

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 23/81 (28%), Positives = 41/81 (50%)
 Frame = +1

Query: 247 NKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGIAGDRMYELYKEY 426
           N+++++ LIHDL E   GD   +   + E K   E    + +  L    G+    L+ ++
Sbjct: 60  NRVIKMLLIHDLGEIDAGDTIIYASETVENKQNEEAGLKRILDLLPDGLGEEYLSLWHDF 119

Query: 427 EDQSSPEAKFAKDLDRYDMIL 489
           E   + E+K+AK +DR   +L
Sbjct: 120 EASETAESKYAKAIDRVPPLL 140


>UniRef50_Q5WZR1 Cluster: Putative uncharacterized protein; n=4;
           Legionella pneumophila|Rep: Putative uncharacterized
           protein - Legionella pneumophila (strain Lens)
          Length = 198

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 26/88 (29%), Positives = 47/88 (53%)
 Frame = +1

Query: 238 IGQNKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGIAGDRMYELY 417
           + + K +++ LIHD+ E   GD+      + ++K + E EA++ +S +    G  +  L+
Sbjct: 63  VDELKTMKLVLIHDVVEIYAGDVFAFDVEARKDKEKVELEALEKLSAVYPSFGIELDSLW 122

Query: 418 KEYEDQSSPEAKFAKDLDRYDMILQAFE 501
            E+E++ S EAK AK  D    I Q  +
Sbjct: 123 HEFEERKSLEAKIAKAADAICPIFQRLQ 150


>UniRef50_Q1GH96 Cluster: HD domain protein; n=6;
           Rhodobacteraceae|Rep: HD domain protein - Silicibacter
           sp. (strain TM1040)
          Length = 388

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 28/82 (34%), Positives = 44/82 (53%), Gaps = 1/82 (1%)
 Frame = +1

Query: 250 KILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGIA-GDRMYELYKEY 426
           +++++ L+HD+ E  VGD         E   + ED A + I GL   A G R+  L++E+
Sbjct: 62  RVIEMLLLHDIVEIDVGDHPIDEPTDWEAVAQAEDRAQRRIFGLLPEAQGHRLQALWQEF 121

Query: 427 EDQSSPEAKFAKDLDRYDMILQ 492
           E   + +A+FAK LD    I Q
Sbjct: 122 EAAHTADARFAKSLDYCQPIFQ 143



 Score = 41.1 bits (92), Expect = 0.025
 Identities = 22/85 (25%), Positives = 42/85 (49%), Gaps = 4/85 (4%)
 Frame = +1

Query: 247 NKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGIAGDRMYE----L 414
           +++L++ L+HDL E   GD+  H  +      + E+        + G+  D   +    +
Sbjct: 251 SRVLKMLLLHDLVEIDAGDVPIHSNLDAAALRQIEETEKAAAERIFGLLPDAQAKDCLMI 310

Query: 415 YKEYEDQSSPEAKFAKDLDRYDMIL 489
           ++E+E   S +A FAK +DR   +L
Sbjct: 311 WQEFEAAQSADAVFAKSIDRVQPVL 335


>UniRef50_A5KNZ3 Cluster: Putative uncharacterized protein; n=4;
           Clostridiales|Rep: Putative uncharacterized protein -
           Ruminococcus torques ATCC 27756
          Length = 210

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 28/81 (34%), Positives = 42/81 (51%), Gaps = 1/81 (1%)
 Frame = +1

Query: 250 KILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISG-LTGIAGDRMYELYKEY 426
           K++ + LIHDL E   GD   +     + K  RE +A + I G L    G     L+ E+
Sbjct: 76  KVIVMVLIHDLVEIDAGDTYAYDSEGTKSKRERELKAAERIFGILPKDQGTYFRSLWDEF 135

Query: 427 EDQSSPEAKFAKDLDRYDMIL 489
           E+ S+ +AKFA  LD +  +L
Sbjct: 136 EEYSTEDAKFAHLLDNFQPLL 156


>UniRef50_A0NM90 Cluster: Metal dependent phosphohydrolase; n=2;
           Alphaproteobacteria|Rep: Metal dependent
           phosphohydrolase - Stappia aggregata IAM 12614
          Length = 206

 Score = 46.0 bits (104), Expect = 9e-04
 Identities = 25/82 (30%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
 Frame = +1

Query: 250 KILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTI-SGLTGIAGDRMYELYKEY 426
           K+L++AL+HDL E I GD+        + +  RE     T+   L     + +  L+ EY
Sbjct: 73  KLLKLALVHDLGEAISGDVPAPLQTPGDNRQERERRDFLTLCEPLPADIAEELLSLWDEY 132

Query: 427 EDQSSPEAKFAKDLDRYDMILQ 492
               + EA+ AK  D+ + +LQ
Sbjct: 133 AAAVTAEARIAKAFDKLETMLQ 154


>UniRef50_A7B2L5 Cluster: Putative uncharacterized protein; n=1;
           Ruminococcus gnavus ATCC 29149|Rep: Putative
           uncharacterized protein - Ruminococcus gnavus ATCC 29149
          Length = 195

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 28/88 (31%), Positives = 41/88 (46%), Gaps = 1/88 (1%)
 Frame = +1

Query: 250 KILQIALIHDLAECIVGDLTPHCGVSPEEKHRRED-EAMKTISGLTGIAGDRMYELYKEY 426
           K+L + LIHDL E   GD+       P  K ++E  +  +    L          L+ EY
Sbjct: 59  KVLSMCLIHDLGELYAGDIPAISNTDPLAKSKQEYLDICRIFQLLPEPKRSEFLSLWNEY 118

Query: 427 EDQSSPEAKFAKDLDRYDMILQAFEYEN 510
            + S PEA   K LD+ + ILQ  + +N
Sbjct: 119 NNCSIPEAHLVKALDKAETILQHNQGKN 146


>UniRef50_A4BKM6 Cluster: Possible metal dependent phosphohydrolase;
           n=1; Reinekea sp. MED297|Rep: Possible metal dependent
           phosphohydrolase - Reinekea sp. MED297
          Length = 189

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 20/75 (26%), Positives = 46/75 (61%)
 Frame = +1

Query: 250 KILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGIAGDRMYELYKEYE 429
           K+ ++AL HD+ E + GD+  +   +PE+  + E   ++++   + + GD + +L++EYE
Sbjct: 58  KLFKMALCHDVCEIVAGDVCAY-DRAPEQTEK-ERAYLESLRQRSPVLGDEILQLWQEYE 115

Query: 430 DQSSPEAKFAKDLDR 474
              +PE+++ +  D+
Sbjct: 116 QGETPESQWVRVFDK 130


>UniRef50_A3CNR6 Cluster: Hydrolase, putative; n=2;
           Streptococcus|Rep: Hydrolase, putative - Streptococcus
           sanguinis (strain SK36)
          Length = 196

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 33/113 (29%), Positives = 51/113 (45%), Gaps = 1/113 (0%)
 Frame = +1

Query: 166 DNSRPHVQDGNHDILTNRRK*SY*IGQNKILQIALIHDLAECIVGDLTPHCGVSPEEKHR 345
           +NS  H   G    L  R      +   K++ + LIHDL E   GD      V   + + 
Sbjct: 34  ENSAEHSWQGALMALVFREYIPEEVNLEKVMSMLLIHDLGEIYAGDTFIFDDVGKSDSYD 93

Query: 346 REDEAMK-TISGLTGIAGDRMYELYKEYEDQSSPEAKFAKDLDRYDMILQAFE 501
           RE E++K ++  L     +    L++E+E   S EAK+A+ LD    +L   E
Sbjct: 94  RELESLKISLGKLPSDQRESFLGLWQEFETGVSIEAKYARVLDALVPLLNHLE 146


>UniRef50_A7CNS4 Cluster: Metal dependent phosphohydrolase; n=3;
           Bacteria|Rep: Metal dependent phosphohydrolase -
           Opitutaceae bacterium TAV2
          Length = 209

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 26/82 (31%), Positives = 44/82 (53%), Gaps = 2/82 (2%)
 Frame = +1

Query: 250 KILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLT--GIAGDRMYELYKE 423
           +++++ LIHD+ E   GD   +   +   +H RE  A   +  L     A D    L++E
Sbjct: 69  RVIKMLLIHDIVEIDAGDTYAYDTAAAATQHERETRAADRLFHLLPQDQAAD-FRALWEE 127

Query: 424 YEDQSSPEAKFAKDLDRYDMIL 489
           +E +++PE++FA  LDR   IL
Sbjct: 128 FESRATPESRFAAALDRVQPIL 149


>UniRef50_Q9R6H4 Cluster: Tiorf85 protein; n=1; Agrobacterium
           tumefaciens|Rep: Tiorf85 protein - Agrobacterium
           tumefaciens
          Length = 222

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 29/83 (34%), Positives = 48/83 (57%), Gaps = 3/83 (3%)
 Frame = +1

Query: 253 ILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDE--AMKTISG-LTGIAGDRMYELYKE 423
           +L++ ++HDLAE  VGD+ P   VS  +  + E E  A+  I   L   +G  +  L+ E
Sbjct: 68  VLKLIIVHDLAEVKVGDI-PVFEVSDRKNAKMEAELAAISEIQAMLPEESGKLITSLWHE 126

Query: 424 YEDQSSPEAKFAKDLDRYDMILQ 492
           YE  ++ EA+FA+ LD  ++ +Q
Sbjct: 127 YEAATTVEARFARALDHLEVQVQ 149


>UniRef50_Q1ZH93 Cluster: Predicted hydrolase; n=5;
           Gammaproteobacteria|Rep: Predicted hydrolase -
           Psychromonas sp. CNPT3
          Length = 197

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 29/112 (25%), Positives = 52/112 (46%), Gaps = 2/112 (1%)
 Frame = +1

Query: 238 IGQNKILQIALIHDLAECIVGDLTPHCGVSPEEKHRRED--EAMKTISGLTGIAGDRMYE 411
           I  ++++++ LIHD+ E   GDL      S  +   +++   A +  S L      +M  
Sbjct: 58  INIDRVIKMLLIHDVIEIDAGDLFAFAAASDHKLQAKKELAAAQRLFSLLPEAQYQKMQA 117

Query: 412 LYKEYEDQSSPEAKFAKDLDRYDMILQAFEYENVKILQRNVKSSLLQQRENL 567
           L+ E+ED  + +A+FAK +DR   +L     E    +   V +  +  R  L
Sbjct: 118 LWIEFEDAITADARFAKSIDRILPVLLNMAAEGGSWVTHKVHAQQVLTRNQL 169


>UniRef50_A1DAC9 Cluster: Putative uncharacterized protein; n=1;
           Neosartorya fischeri NRRL 181|Rep: Putative
           uncharacterized protein - Neosartorya fischeri (strain
           ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus
           fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181))
          Length = 120

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 28/85 (32%), Positives = 46/85 (54%), Gaps = 3/85 (3%)
 Frame = +1

Query: 262 IALIHDLA---ECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGIAGDRMYELYKEYED 432
           +AL+HD+A   EC+VGD+TP                 K + G+T I  +    L++ YE+
Sbjct: 1   MALVHDMADMAECLVGDITP---------------LHKLLPGVTDI--NTFTALFRGYEE 43

Query: 433 QSSPEAKFAKDLDRYDMILQAFEYE 507
             + EA+   D+++ + +LQ FEYE
Sbjct: 44  NQTLEAQLVHDINKLERVLQTFEYE 68


>UniRef50_Q895R8 Cluster: Hydrolase; n=6; Clostridiales|Rep:
           Hydrolase - Clostridium tetani
          Length = 193

 Score = 43.6 bits (98), Expect = 0.005
 Identities = 23/82 (28%), Positives = 42/82 (51%)
 Frame = +1

Query: 247 NKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGIAGDRMYELYKEY 426
           NK++ + + HDL E I GD+ P    +  ++    +   K +  L       +  L+KE 
Sbjct: 64  NKVILMCICHDLGEAITGDI-PAFYKTESDEIVESNAVYKLLDSLPQPYKKELTNLFKEM 122

Query: 427 EDQSSPEAKFAKDLDRYDMILQ 492
           ++Q + EAK  K LD+ + ++Q
Sbjct: 123 DEQQTLEAKLYKALDKMETLIQ 144


>UniRef50_A5FA91 Cluster: Metal dependent phosphohydrolase; n=2;
           Bacteroidetes|Rep: Metal dependent phosphohydrolase -
           Flavobacterium johnsoniae UW101
          Length = 222

 Score = 43.6 bits (98), Expect = 0.005
 Identities = 25/82 (30%), Positives = 42/82 (51%), Gaps = 1/82 (1%)
 Frame = +1

Query: 250 KILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGI-AGDRMYELYKEY 426
           K++++ LIHD+ E   GD+  +  V        E  A   I GL      +    +++E+
Sbjct: 89  KVVKMVLIHDIVEIDAGDVFIYDTVKNHSNTDEERLAANRIFGLLPKNQAEEFISIWEEF 148

Query: 427 EDQSSPEAKFAKDLDRYDMILQ 492
           E   + EAKFA+ +DR + +LQ
Sbjct: 149 EAGETNEAKFARSMDRLEPLLQ 170


>UniRef50_Q4FQC9 Cluster: Possible metal dependent phosphohydrolase;
           n=5; Gammaproteobacteria|Rep: Possible metal dependent
           phosphohydrolase - Psychrobacter arcticum
          Length = 214

 Score = 43.2 bits (97), Expect = 0.006
 Identities = 24/79 (30%), Positives = 40/79 (50%)
 Frame = +1

Query: 238 IGQNKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGIAGDRMYELY 417
           + Q K+L++AL+HDL E   GD   +   +  + H  E   +  + G  G     + E++
Sbjct: 78  VNQEKLLKMALVHDLGEIDAGDTFLYAD-TRGDAHLEERAGIARLQGERGNGISNLNEIW 136

Query: 418 KEYEDQSSPEAKFAKDLDR 474
           +E E  SS E +  K +DR
Sbjct: 137 EEQETGSSTETQLLKVVDR 155


>UniRef50_Q1LGM8 Cluster: Hydrolases of HD superfamily-like protein;
           n=8; Proteobacteria|Rep: Hydrolases of HD
           superfamily-like protein - Ralstonia metallidurans
           (strain CH34 / ATCC 43123 / DSM 2839)
          Length = 224

 Score = 43.2 bits (97), Expect = 0.006
 Identities = 25/81 (30%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
 Frame = +1

Query: 250 KILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGIAGDRMYE-LYKEY 426
           +++++ LIHD+ E   GD+  H   +   +   E++A + I  L   A    +  L+ E+
Sbjct: 91  RVVKMLLIHDIVEIDAGDVPFHDPAARAGQAALEEQAAERIFSLLPAAQAAEFRSLWSEF 150

Query: 427 EDQSSPEAKFAKDLDRYDMIL 489
           E   S +A+FAK LDR   +L
Sbjct: 151 EAGESDDARFAKSLDRLQPLL 171


>UniRef50_A4FQR8 Cluster: Metal-dependent phosphohydrolase, HD
           region; n=4; Bacteria|Rep: Metal-dependent
           phosphohydrolase, HD region - Saccharopolyspora
           erythraea (strain NRRL 23338)
          Length = 213

 Score = 43.2 bits (97), Expect = 0.006
 Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 1/85 (1%)
 Frame = +1

Query: 238 IGQNKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGI-AGDRMYEL 414
           I   + +Q+ ++HDL E   GD   +   +  ++  RE  A   +  L      +    L
Sbjct: 74  IDVGRTIQLVVVHDLIEIYAGDTPLYDAEAGHDQEARERAAADRLFPLLPADQAEHFRAL 133

Query: 415 YKEYEDQSSPEAKFAKDLDRYDMIL 489
           + E+E + +PEA+FAK +DR    L
Sbjct: 134 WDEFEQRRTPEARFAKAMDRLQPFL 158


>UniRef50_Q1K3X2 Cluster: Metal dependent phosphohydrolase; n=4;
           Deltaproteobacteria|Rep: Metal dependent
           phosphohydrolase - Desulfuromonas acetoxidans DSM 684
          Length = 201

 Score = 42.7 bits (96), Expect = 0.008
 Identities = 27/90 (30%), Positives = 47/90 (52%), Gaps = 2/90 (2%)
 Frame = +1

Query: 250 KILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGIA--GDRMYELYKE 423
           +++ + L HD+ E  +GDL         +K+ + DE  K I  L      G++  +   E
Sbjct: 57  RVVMLCLFHDVPEARIGDLN-----YVNKKYVQADE-QKAIDDLAATLPFGEQYKQTLGE 110

Query: 424 YEDQSSPEAKFAKDLDRYDMILQAFEYENV 513
           + D+ +PEA  A D D+ +MIL   EY+++
Sbjct: 111 FVDKETPEACLAHDADQLEMILALKEYKDL 140


>UniRef50_Q4JA64 Cluster: Conserved Archaeal protein; n=4;
           Sulfolobaceae|Rep: Conserved Archaeal protein -
           Sulfolobus acidocaldarius
          Length = 177

 Score = 42.3 bits (95), Expect = 0.011
 Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 4/107 (3%)
 Frame = +1

Query: 238 IGQNKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGIAGDRMYELY 417
           +   K + IA+ HD+ E ++GDL          K   E EA++    + GI G+   EL+
Sbjct: 56  VNAEKAVTIAVFHDIGETLLGDLPKWATEKIGNKKELESEAIR----ILGI-GE---ELF 107

Query: 418 KEYEDQSSPEAKFAKDLDRYDMILQAFEYE----NVKILQRNVKSSL 546
            EY + ++ E + AK  D+    LQA  Y     NVK +  N K+ L
Sbjct: 108 NEY-NSTTIEGRLAKLCDKLSTYLQALRYSKQGYNVKEIVENYKTEL 153


>UniRef50_A7JP66 Cluster: Predicted protein; n=1; Francisella
           tularensis subsp. novicida GA99-3548|Rep: Predicted
           protein - Francisella tularensis subsp. novicida
           GA99-3548
          Length = 196

 Score = 41.9 bits (94), Expect = 0.014
 Identities = 25/81 (30%), Positives = 45/81 (55%), Gaps = 2/81 (2%)
 Frame = +1

Query: 238 IGQNKILQIALIHDLAECIVGDLTPHCGVSPEE-KHRREDEAM-KTISGLTGIAGDRMYE 411
           I   ++L + LIHD+ E   GD       +  E +H++E  A+ K +S +       + +
Sbjct: 58  INMERVLTMLLIHDIVEIYAGDTYAFDDEAILELQHKKELLALDKILSLMPEYDAKELKK 117

Query: 412 LYKEYEDQSSPEAKFAKDLDR 474
           L+ E+E+ SS +AK+AK +D+
Sbjct: 118 LWLEFEESSSADAKYAKAIDK 138


>UniRef50_A3JYJ9 Cluster: HD domain protein; n=1; Sagittula stellata
           E-37|Rep: HD domain protein - Sagittula stellata E-37
          Length = 204

 Score = 41.9 bits (94), Expect = 0.014
 Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
 Frame = +1

Query: 238 IGQNKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGIAGDRMYE-L 414
           + + K++ + L+HDL E   GD               E  A   I GL      + +  +
Sbjct: 63  VDRGKVIAMLLLHDLVEIDAGDAPVFGNHDTAAVEAAEARAADRIFGLLPEDQRQHFRAI 122

Query: 415 YKEYEDQSSPEAKFAKDLDRY 477
           ++E+E   +PEA+FAK LDR+
Sbjct: 123 WEEFEANQTPEARFAKSLDRF 143


>UniRef50_Q2SNR5 Cluster: Predicted Hydrolase of HD superfamily;
           n=1; Hahella chejuensis KCTC 2396|Rep: Predicted
           Hydrolase of HD superfamily - Hahella chejuensis (strain
           KCTC 2396)
          Length = 192

 Score = 41.1 bits (92), Expect = 0.025
 Identities = 24/82 (29%), Positives = 45/82 (54%), Gaps = 1/82 (1%)
 Frame = +1

Query: 247 NKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISG-LTGIAGDRMYELYKE 423
           N+++++ L+HD+ E   GD         + ++  E +A + I G L    GD    L+ E
Sbjct: 61  NRVVRMLLLHDVVEIDAGDKFIFSAAHADTEN--EMKAAERIFGMLPPQVGDEFKALWLE 118

Query: 424 YEDQSSPEAKFAKDLDRYDMIL 489
           YE++ +PE+++A  +DR   +L
Sbjct: 119 YEERRTPESRYAYAMDRLMPVL 140


>UniRef50_Q22973 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 75

 Score = 41.1 bits (92), Expect = 0.025
 Identities = 18/32 (56%), Positives = 25/32 (78%)
 Frame = +1

Query: 412 LYKEYEDQSSPEAKFAKDLDRYDMILQAFEYE 507
           L+KEYE+ SS  A+  K LD++DMI+QA +YE
Sbjct: 2   LWKEYEEASSLTARVVKHLDKFDMIVQADKYE 33


>UniRef50_Q4SC46 Cluster: Chromosome 14 SCAF14660, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 14 SCAF14660, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 95

 Score = 40.7 bits (91), Expect = 0.033
 Identities = 16/45 (35%), Positives = 27/45 (60%)
 Frame = +2

Query: 86  LLFITQYFSKKHVKRTGWILCDINDCETIAGHMYRMGIMTFLLTE 220
           L F+      K V RTGW+  ++   E+++ HMYRM +M+  +T+
Sbjct: 16  LQFLKLIGQLKRVPRTGWVYRNVKKPESVSDHMYRMAVMSLTITD 60


>UniRef50_UPI00006CA3B0 Cluster: hypothetical protein
           TTHERM_00525080; n=1; Tetrahymena thermophila SB210|Rep:
           hypothetical protein TTHERM_00525080 - Tetrahymena
           thermophila SB210
          Length = 219

 Score = 40.3 bits (90), Expect = 0.044
 Identities = 33/110 (30%), Positives = 54/110 (49%), Gaps = 7/110 (6%)
 Frame = +1

Query: 250 KILQIALIHDLAECIVGDLTPHCGVSPEEKHRR---EDEAM-KTISGLTGIAGDRMYELY 417
           K + +A IHDL E + GD+ P        K ++   E +A+ K    L     +++   Y
Sbjct: 65  KCVLMASIHDLPEALCGDI-PIINQDKNVKKQKDILEHQALIKMTESLDEDIKNKLRNAY 123

Query: 418 KEYEDQSSPEAKFAKDLDRYDMILQAFEYENVKIL---QRNVKSSLLQQR 558
            EYE Q + E+K+ K LD+    ++AF+  N+  L   ++  K  L Q R
Sbjct: 124 DEYEAQQTVESKYVKALDK----IEAFQQHNLDPLDTWEQKEKEMLFQDR 169


>UniRef50_Q5BRU0 Cluster: SJCHGC07393 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC07393 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 80

 Score = 39.9 bits (89), Expect = 0.058
 Identities = 24/60 (40%), Positives = 32/60 (53%), Gaps = 1/60 (1%)
 Frame = +2

Query: 71  ESRIKLLFITQYFSKKHVKRTGWILCDINDCETIAGHMYRMGIM-TFLLTEENNPTKLDR 247
           ES I L F+      K   RTGW   +I+  E+++ HMYRM +M T + TEE      DR
Sbjct: 3   ESNI-LRFLLICGKLKRTVRTGWTRYNISSPESVSDHMYRMALMATVIPTEERKNLNTDR 61


>UniRef50_Q47TN5 Cluster: Metal-dependent phosphohydrolase, HD
           region; n=1; Thermobifida fusca YX|Rep: Metal-dependent
           phosphohydrolase, HD region - Thermobifida fusca (strain
           YX)
          Length = 208

 Score = 38.3 bits (85), Expect = 0.18
 Identities = 24/88 (27%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
 Frame = +1

Query: 253 ILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGIAGDRMY---ELYKE 423
           ++ + L+HD+ E   GD   +   +   +  RE  A   I  L  +  D+      L+ E
Sbjct: 75  VVNMLLVHDIVEIDAGDTYIYDQAAVSTQAERERAAADRIFAL--LPEDQAVWARNLWDE 132

Query: 424 YEDQSSPEAKFAKDLDRYDMILQAFEYE 507
           +E++ +PEA+FA+ +DR   +L  +  E
Sbjct: 133 FEERKTPEARFARAIDRLSPLLANWHTE 160


>UniRef50_A6BZR0 Cluster: Metal dependent phosphohydrolase; n=1;
           Planctomyces maris DSM 8797|Rep: Metal dependent
           phosphohydrolase - Planctomyces maris DSM 8797
          Length = 150

 Score = 37.9 bits (84), Expect = 0.23
 Identities = 24/76 (31%), Positives = 40/76 (52%)
 Frame = +1

Query: 247 NKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGIAGDRMYELYKEY 426
           +K++++AL+HDL E   GD T     +  + H  E + ++ I+   G     +  L++E 
Sbjct: 17  SKLIKLALLHDLGEIEAGD-TFLYSTNRSDAHIEERKCVEKIALHPGNPIGNIIGLWEEQ 75

Query: 427 EDQSSPEAKFAKDLDR 474
           E   S EAK  K +DR
Sbjct: 76  EAGESKEAKLLKVIDR 91


>UniRef50_A6BKU8 Cluster: Putative uncharacterized protein; n=2;
           Bacteria|Rep: Putative uncharacterized protein - Dorea
           longicatena DSM 13814
          Length = 338

 Score = 37.9 bits (84), Expect = 0.23
 Identities = 21/83 (25%), Positives = 41/83 (49%), Gaps = 1/83 (1%)
 Frame = +1

Query: 247 NKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISG-LTGIAGDRMYELYKE 423
           +K+++++L HDL E + GD+     V  +     E+ A+  ++  L       +  L+ E
Sbjct: 61  DKVMRMSLFHDLGEAVTGDIPAF--VKTDSDREVEESAISNVTAMLPERERKELDALFDE 118

Query: 424 YEDQSSPEAKFAKDLDRYDMILQ 492
            E   + EAK    LD+ + ++Q
Sbjct: 119 LEKAETMEAKIVHALDKMEALIQ 141


>UniRef50_Q4HMC9 Cluster: ATP-dependent nuclease (AddB), putative;
           n=1; Campylobacter lari RM2100|Rep: ATP-dependent
           nuclease (AddB), putative - Campylobacter lari RM2100
          Length = 411

 Score = 37.5 bits (83), Expect = 0.31
 Identities = 23/81 (28%), Positives = 43/81 (53%), Gaps = 2/81 (2%)
 Frame = +1

Query: 388 IAGDRMYELYKEYEDQSSPEAKFAKDLDRYDMILQAFEYEN--VKILQRNVKSSLLQQRE 561
           I  ++ Y  Y+   D  + +A + K L++Y++  + FE+EN  +KI++ N+K+  + Q +
Sbjct: 114 IKEEQDYRNYEILGDIFAKKALYTKALEQYNLAYKLFEHENLLLKIVEINIKNKNINQAK 173

Query: 562 NLTTRLYKI*SKNCTCKEKSL 624
                  K  S  CT K  +L
Sbjct: 174 KALEEFVK--SSQCTLKTCTL 192


>UniRef50_A1G3Q4 Cluster: Metal dependent phosphohydrolase; n=4;
           Actinomycetales|Rep: Metal dependent phosphohydrolase -
           Salinispora arenicola CNS205
          Length = 569

 Score = 37.5 bits (83), Expect = 0.31
 Identities = 24/100 (24%), Positives = 44/100 (44%), Gaps = 2/100 (2%)
 Frame = +1

Query: 250 KILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGIAGDRMYELYKEYE 429
           ++  + ++HD  E  + D+ PH                  ++       D +     EYE
Sbjct: 439 RVSMLCVLHDTQETRITDI-PHIAKRYLTTAPNTTVTADQVAACPPTVADLITAAVTEYE 497

Query: 430 DQSSPEAKFAKDLDRYDMILQAFEY--ENVKILQRNVKSS 543
              +PEA  A+D D+ + ++QA EY  + +  +QR + SS
Sbjct: 498 AGETPEAIVARDADKLECLVQAVEYRHQGINNVQRWIDSS 537


>UniRef50_A0Q525 Cluster: Hydrolase, HD superfamily; n=12;
           Francisella tularensis|Rep: Hydrolase, HD superfamily -
           Francisella tularensis subsp. novicida (strain U112)
          Length = 196

 Score = 37.5 bits (83), Expect = 0.31
 Identities = 23/85 (27%), Positives = 38/85 (44%), Gaps = 2/85 (2%)
 Frame = +1

Query: 250 KILQIALIHDLAECIVGDLTPHCGVSP--EEKHRREDEAMKTISGLTGIAGDRMYELYKE 423
           K+ ++ LIHD+ E   GD            +KH       +    L    G ++ +L+ E
Sbjct: 63  KVTKMLLIHDIVEIYSGDTFAFADSQTLDSQKHSELAAIQRIAKILPKPQGQQLEQLWLE 122

Query: 424 YEDQSSPEAKFAKDLDRYDMILQAF 498
           ++   + EAKFA  +DR    +Q F
Sbjct: 123 FDSAETNEAKFANAIDRLVPAIQNF 147


>UniRef50_A2BL70 Cluster: Predicted hydrolase of HD superfamily;
           n=1; Hyperthermus butylicus DSM 5456|Rep: Predicted
           hydrolase of HD superfamily - Hyperthermus butylicus
           (strain DSM 5456 / JCM 9403)
          Length = 197

 Score = 37.5 bits (83), Expect = 0.31
 Identities = 24/83 (28%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
 Frame = +1

Query: 262 IALIHDLAECIVGDLTPHC--GVSPEEKHRREDEAMKTISGLTGIAGDRMYELYKEYEDQ 435
           +A++HD AE IVGD+  +    +  E K R E EA +       I    + +L +EY  Q
Sbjct: 70  VAIVHDAAEAIVGDIVKYTAEAMGKELKERIEVEAAR-----KEIPSVLLLKLLEEYVAQ 124

Query: 436 SSPEAKFAKDLDRYDMILQAFEY 504
           ++ E++  K  +    ++Q+  Y
Sbjct: 125 NTMESELVKIAEMLSTLIQSLRY 147



 Score = 33.9 bits (74), Expect = 3.8
 Identities = 16/38 (42%), Positives = 21/38 (55%), Gaps = 2/38 (5%)
 Frame = +2

Query: 116 KHVKRTGWILCDINDC--ETIAGHMYRMGIMTFLLTEE 223
           K   RTGW+L  +     ETIA HMY   ++  +L EE
Sbjct: 17  KTTPRTGWLLRGVYPAIAETIAAHMYESAVLALMLGEE 54


>UniRef50_Q6M9P4 Cluster: Putative uncharacterized protein; n=1;
           Candidatus Protochlamydia amoebophila UWE25|Rep:
           Putative uncharacterized protein - Protochlamydia
           amoebophila (strain UWE25)
          Length = 186

 Score = 36.3 bits (80), Expect = 0.71
 Identities = 24/84 (28%), Positives = 41/84 (48%)
 Frame = +1

Query: 238 IGQNKILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGIAGDRMYELY 417
           I + K++ + L+HDL E  +GDL     V  +       +A+  +S    + G  +    
Sbjct: 42  IDRYKLVMMCLLHDLPESRIGDLN---YVQKKYVTPNISKALHDLSN-ESVLGPEIVNWI 97

Query: 418 KEYEDQSSPEAKFAKDLDRYDMIL 489
           +EYE   S EA+ A D D+ + +L
Sbjct: 98  EEYEKGESLEAQIAHDADQIEFLL 121


>UniRef50_Q23UG8 Cluster: Peptidase M16 inactive domain containing
            protein; n=1; Tetrahymena thermophila SB210|Rep:
            Peptidase M16 inactive domain containing protein -
            Tetrahymena thermophila SB210
          Length = 1007

 Score = 36.3 bits (80), Expect = 0.71
 Identities = 17/49 (34%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
 Frame = -2

Query: 345  SVFFFRTHSTV-RCEVSNNALSQVVNESYLKNFILSNLVGLFSSVSKNV 202
            SVF +R HSTV R E    A+  + N+ + +  +    + LFS + KN+
Sbjct: 858  SVFSYRDHSTVQRYETFERAIQYITNKDFTERELKEAKISLFSKIDKNI 906


>UniRef50_A1RZE6 Cluster: Metal dependent phosphohydrolase; n=1;
           Thermofilum pendens Hrk 5|Rep: Metal dependent
           phosphohydrolase - Thermofilum pendens (strain Hrk 5)
          Length = 200

 Score = 36.3 bits (80), Expect = 0.71
 Identities = 26/98 (26%), Positives = 48/98 (48%), Gaps = 1/98 (1%)
 Frame = +1

Query: 202 DILTNRRK*SY*IGQNKILQIALIHDLAECIVGDLTPHCGVSPEEKH-RREDEAMKTISG 378
           D+    R+  + +   K+L ++++HD+AE + GD+  +     EE   + E+EA++++ G
Sbjct: 43  DVARRARERGFELELEKVLAMSILHDVAEAVTGDVVRYVKQLDEELFGKAEEEALRSL-G 101

Query: 379 LTGIAGDRMYELYKEYEDQSSPEAKFAKDLDRYDMILQ 492
           L   +      L  E     SPEA   K  D    I++
Sbjct: 102 LGAYSA-----LLAELRRLESPEALVVKASDDLATIIE 134


>UniRef50_A6CJT6 Cluster: Putative uncharacterized protein; n=1;
           Bacillus sp. SG-1|Rep: Putative uncharacterized protein
           - Bacillus sp. SG-1
          Length = 194

 Score = 35.1 bits (77), Expect = 1.6
 Identities = 24/106 (22%), Positives = 44/106 (41%), Gaps = 1/106 (0%)
 Frame = +1

Query: 250 KILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISG-LTGIAGDRMYELYKEY 426
           K +++ L+HD+ E   GD         ++K +RE  A   + G L     D     + EY
Sbjct: 60  KSIKMLLLHDIVEIDAGDTYAFDEDGYQDKQQREKLAADRLYGMLPESVRDDYRSTWNEY 119

Query: 427 EDQSSPEAKFAKDLDRYDMILQAFEYENVKILQRNVKSSLLQQREN 564
           E+  + EA FA  +D    ++       +   +  + S  +  R +
Sbjct: 120 EEGKTHEALFAHIIDHIQPLMLNIATSGISWKEHGIHSHQVMNRNS 165


>UniRef50_A0DXX1 Cluster: Chromosome undetermined scaffold_69, whole
            genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_69, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 3066

 Score = 35.1 bits (77), Expect = 1.6
 Identities = 19/86 (22%), Positives = 41/86 (47%)
 Frame = +1

Query: 331  EEKHRREDEAMKTISGLTGIAGDRMYELYKEYEDQSSPEAKFAKDLDRYDMILQAFEYEN 510
            ++K  +E E +K +        +  Y L  + +D +  E + AK+LD     ++  E+E 
Sbjct: 2633 QDKFTKESELLKDLQNKIKQTAESHYALSLQLKDWAEKENRLAKELDTRRQSVEQIEFEL 2692

Query: 511  VKILQRNVKSSLLQQRENLTTRLYKI 588
              +  +  +S L  ++ N+  R+Y +
Sbjct: 2693 QAVFAK--QSDLESEKVNVLQRIYSL 2716


>UniRef50_Q4Y5N6 Cluster: Putative uncharacterized protein; n=1;
           Plasmodium chabaudi|Rep: Putative uncharacterized
           protein - Plasmodium chabaudi
          Length = 326

 Score = 33.9 bits (74), Expect = 3.8
 Identities = 14/38 (36%), Positives = 25/38 (65%)
 Frame = +1

Query: 457 AKDLDRYDMILQAFEYENVKILQRNVKSSLLQQRENLT 570
           + + D  +++ QAF YENVKIL+ +++ S   ++ N T
Sbjct: 90  SSNYDDLNLLAQAFNYENVKILKSHLEGSTTNKKRNNT 127


>UniRef50_P11532 Cluster: Dystrophin; n=138; Eukaryota|Rep: Dystrophin
            - Homo sapiens (Human)
          Length = 3685

 Score = 33.9 bits (74), Expect = 3.8
 Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 2/103 (1%)
 Frame = +1

Query: 283  AECIVGDLTPHCGVSPEE--KHRREDEAMKTISGLTGIAGDRMYELYKEYEDQSSPEAKF 456
            A+ I  DLT H  +S EE  KH +  EA + +     +A  ++ ++  ++     P A F
Sbjct: 1410 AQKIQSDLTSH-EISLEEMKKHNQGKEAAQRVLSQIDVAQKKLQDVSMKFRLFQKP-ANF 1467

Query: 457  AKDLDRYDMILQAFEYENVKILQRNVKSSLLQQRENLTTRLYK 585
             + L    MIL   +     +  ++V+  ++Q + N    LYK
Sbjct: 1468 EQRLQESKMILDEVKMHLPALETKSVEQEVVQSQLNHCVNLYK 1510


>UniRef50_Q9RWG4 Cluster: Putative uncharacterized protein; n=1;
           Deinococcus radiodurans|Rep: Putative uncharacterized
           protein - Deinococcus radiodurans
          Length = 198

 Score = 33.5 bits (73), Expect = 5.0
 Identities = 25/85 (29%), Positives = 46/85 (54%), Gaps = 5/85 (5%)
 Frame = +1

Query: 250 KILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEA-MKTISGLTG-IAGDRMYE---L 414
           +++++ L+HDL E   GDL+     +P E    + EA  +  + L G +  D+  E   L
Sbjct: 62  RVVRLLLMHDLVEIGAGDLSFD---APAEAQAAQQEAEARAAAELFGLLPTDQAAEFLGL 118

Query: 415 YKEYEDQSSPEAKFAKDLDRYDMIL 489
           ++E+E + + E +FA+ LD    +L
Sbjct: 119 WQEFEARQTTEVRFARALDALQPML 143


>UniRef50_Q16YM0 Cluster: Cohesin-subunit, putative; n=3;
           Culicidae|Rep: Cohesin-subunit, putative - Aedes aegypti
           (Yellowfever mosquito)
          Length = 882

 Score = 33.5 bits (73), Expect = 5.0
 Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 3/83 (3%)
 Frame = +1

Query: 346 REDEAMKTISGLTG-IAGDRMYELYKEYEDQSSPEAKFAKDLDRYDMILQAFEYENVKIL 522
           +E E  + +SG    I GD ++ L K+   +   E K +++LD Y +IL+  E + +K  
Sbjct: 290 KEMEQNEKLSGFKARIQGD-IHVLEKQVNKEQEEEDKLSRELDHYALILEQTEADMLKAQ 348

Query: 523 QRN--VKSSLLQQRENLTTRLYK 585
           Q    +++ L   R+ L  + +K
Sbjct: 349 QEGLLIENHLKSLRQTLNKQNHK 371


>UniRef50_A2FC18 Cluster: Rap/ran-GAP family protein; n=1;
           Trichomonas vaginalis G3|Rep: Rap/ran-GAP family protein
           - Trichomonas vaginalis G3
          Length = 1130

 Score = 33.5 bits (73), Expect = 5.0
 Identities = 25/74 (33%), Positives = 39/74 (52%)
 Frame = -2

Query: 288 LSQVVNESYLKNFILSNLVGLFSSVSKNVMIPILYMWPAIVSQSLISQRIQPVLLTCFFE 109
           L Q +NESYLK FI + ++   S   KN  +  +Y    I+SQ LI+ + Q  +  C   
Sbjct: 215 LKQPINESYLKKFIPTVIIN--SLYGKNPSMEEIYSTADIISQ-LITPQNQDTI--CSLI 269

Query: 108 KYCVINNNLIRDSL 67
            YC   + L++D +
Sbjct: 270 NYC--PHELVKDQV 281


>UniRef50_Q971B8 Cluster: V-type ATP synthase subunit E; n=2;
           Sulfolobus tokodaii|Rep: V-type ATP synthase subunit E -
           Sulfolobus tokodaii
          Length = 191

 Score = 33.5 bits (73), Expect = 5.0
 Identities = 21/85 (24%), Positives = 41/85 (48%)
 Frame = +1

Query: 331 EEKHRREDEAMKTISGLTGIAGDRMYELYKEYEDQSSPEAKFAKDLDRYDMILQAFEYEN 510
           EEK++  +E  K +S +  I  +   E+Y+EY  + +      K+ DR    +   E EN
Sbjct: 14  EEKNKITEEFKKILSEMNQIIDEAYAEVYREYSAKITDLVN--KNNDRIRGEIAKMEIEN 71

Query: 511 VKILQRNVKSSLLQQRENLTTRLYK 585
            +++ + +   +   +EN    LY+
Sbjct: 72  KRLISKEMDYWIENVKENAKKSLYE 96


>UniRef50_Q10071 Cluster: Probable CAAX prenyl protease 1; n=1;
           Schizosaccharomyces pombe|Rep: Probable CAAX prenyl
           protease 1 - Schizosaccharomyces pombe (Fission yeast)
          Length = 474

 Score = 33.5 bits (73), Expect = 5.0
 Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
 Frame = -2

Query: 279 VVNESYLKNFILSNLVGLFSSV-SKNVMIPILYMWPAIVSQSLISQRIQPVLLTCFFEKY 103
           ++ E  L   ++S +VG+F  + +K     I+Y W A +   LI Q I P L+   F K+
Sbjct: 201 LLKELSLGGLLMSVVVGVFVKILTKFGDNFIMYAWGAYIVFGLILQTIAPSLIMPLFYKF 260

Query: 102 CVINNNLIRDSL 67
             + N  +R  +
Sbjct: 261 TPLENGSLRTQI 272


>UniRef50_Q20EV4 Cluster: Putative septum site-determining protein
           minD; n=15; cellular organisms|Rep: Putative septum
           site-determining protein minD - Oltmannsiellopsis
           viridis (Marine flagellate)
          Length = 316

 Score = 33.5 bits (73), Expect = 5.0
 Identities = 15/47 (31%), Positives = 28/47 (59%)
 Frame = +1

Query: 436 SSPEAKFAKDLDRYDMILQAFEYENVKILQRNVKSSLLQQRENLTTR 576
           ++PE    +D DR   +L++    NVK+L   V+S ++QQ + ++ R
Sbjct: 193 TTPEITSIRDADRVAGLLESNGIYNVKLLVNRVRSEMIQQNDMMSVR 239


>UniRef50_A7MRB0 Cluster: Putative uncharacterized protein; n=1;
           Enterobacter sakazakii ATCC BAA-894|Rep: Putative
           uncharacterized protein - Enterobacter sakazakii ATCC
           BAA-894
          Length = 222

 Score = 33.1 bits (72), Expect = 6.6
 Identities = 27/110 (24%), Positives = 55/110 (50%), Gaps = 2/110 (1%)
 Frame = +1

Query: 334 EKHRREDEAMKTISGLTGIAG--DRMYELYKEYEDQSSPEAKFAKDLDRYDMILQAFEYE 507
           E+ R+  +A+  +    G +G  D +YE YK +   ++ ++    D+ + ++I +A + E
Sbjct: 74  ERLRKPGQALNDLLMSGGSSGQFDELYEKYKIFNTCNTGQSGSYADVCKQEVINKAVQLE 133

Query: 508 NVKILQRNVKSSLLQQRENLTTRLYKI*SKNCTCKEKSLRNIPLSMVMCN 657
               +QR V ++ L + + L+ R+    SK+    +    +I L  VM N
Sbjct: 134 QTNDIQREVDNT-LGEIDRLSNRIAL--SKDSKESQDLANSIQLKSVMLN 180


>UniRef50_A0Y8H0 Cluster: Alpha/beta hydrolase fold protein; n=6;
           Proteobacteria|Rep: Alpha/beta hydrolase fold protein -
           marine gamma proteobacterium HTCC2143
          Length = 315

 Score = 33.1 bits (72), Expect = 6.6
 Identities = 14/53 (26%), Positives = 32/53 (60%), Gaps = 2/53 (3%)
 Frame = -2

Query: 270 ESYLKNFILSNLVGLFSSVSKNVMIPILYMWPAIVSQSLISQRIQPV--LLTC 118
           E+Y  + +L+++ GL  +  K+ ++ I + W A+++     Q+I+P+  L+ C
Sbjct: 83  ENYTMDHLLADVAGLIDASGKSEVVLIAHDWGAVIAWQFAIQKIRPLHKLIIC 135


>UniRef50_Q19007 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 316

 Score = 33.1 bits (72), Expect = 6.6
 Identities = 21/53 (39%), Positives = 30/53 (56%), Gaps = 5/53 (9%)
 Frame = +1

Query: 379 LTGIAGDRMYELYKEYEDQSSPEAKFAKD-----LDRYDMILQAFEYENVKIL 522
           L G+ GD++ ELYK  E  + P AK  KD     L  +D++ +A E  +V IL
Sbjct: 89  LEGLEGDQLAELYKAAE--ADPSAKGIKDFWLTALRTHDLVAEAIEEHDVPIL 139


>UniRef50_Q6FSY5 Cluster: Similar to sp|P47069 Saccharomyces
           cerevisiae YJL019w; n=1; Candida glabrata|Rep: Similar
           to sp|P47069 Saccharomyces cerevisiae YJL019w - Candida
           glabrata (Yeast) (Torulopsis glabrata)
          Length = 659

 Score = 33.1 bits (72), Expect = 6.6
 Identities = 20/56 (35%), Positives = 31/56 (55%), Gaps = 1/56 (1%)
 Frame = +1

Query: 424 YEDQSSPEAKFAKDLDR-YDMILQAFEYENVKILQRNVKSSLLQQRENLTTRLYKI 588
           Y + S  E K  ++LDR   +++  FE    K++ +N+K +L  Q ENL  R  KI
Sbjct: 190 YSEFSQSEQKHVQELDRTLKVVVAQFEKNIKKLIPKNIK-NLQTQVENLNERFNKI 244


>UniRef50_Q7VI11 Cluster: Putative uncharacterized protein; n=1;
           Helicobacter hepaticus|Rep: Putative uncharacterized
           protein - Helicobacter hepaticus
          Length = 1056

 Score = 32.7 bits (71), Expect = 8.8
 Identities = 16/54 (29%), Positives = 28/54 (51%)
 Frame = +1

Query: 472 RYDMILQAFEYENVKILQRNVKSSLLQQRENLTTRLYKI*SKNCTCKEKSLRNI 633
           R  ++ Q F+YE  K+   N++       EN  T+  K+  +    KEK+L+N+
Sbjct: 114 RLSLVTQGFDYEKNKMTFSNLRRQSFTLGENTKTKTAKLQLQGFLDKEKTLKNL 167


>UniRef50_A3YEP7 Cluster: Possible metal dependent phosphohydrolase;
           n=1; Marinomonas sp. MED121|Rep: Possible metal
           dependent phosphohydrolase - Marinomonas sp. MED121
          Length = 194

 Score = 32.7 bits (71), Expect = 8.8
 Identities = 18/75 (24%), Positives = 39/75 (52%)
 Frame = +1

Query: 250 KILQIALIHDLAECIVGDLTPHCGVSPEEKHRREDEAMKTISGLTGIAGDRMYELYKEYE 429
           K++++ L+HD+ E   GD +    V   ++  +E   +  ++           +L++EYE
Sbjct: 62  KVIKMTLVHDICEIGAGDKSIF-DVDRAKQTEKEAAYLSELNRYKIKFATETLDLWQEYE 120

Query: 430 DQSSPEAKFAKDLDR 474
            Q + E+++ K +DR
Sbjct: 121 AQETRESQWVKVVDR 135


>UniRef50_Q23DV3 Cluster: Plasmid Maintenance Protein containing
           protein; n=1; Tetrahymena thermophila SB210|Rep: Plasmid
           Maintenance Protein containing protein - Tetrahymena
           thermophila SB210
          Length = 552

 Score = 32.7 bits (71), Expect = 8.8
 Identities = 21/81 (25%), Positives = 47/81 (58%), Gaps = 3/81 (3%)
 Frame = -2

Query: 285 SQVVNESYLKNFILSNLVGLFSSVSKNV-MIPILYMWP--AIVSQSLISQRIQPVLLTCF 115
           S ++N+S   ++I S +V + + V+K   +IP +++WP   +  Q  + ++   ++L   
Sbjct: 205 SSILNKSSYDDYI-SRVVVIINFVTKPTSIIPFIFIWPITLLTMQGNLKKKFNYLVLN-I 262

Query: 114 FEKYCVINNNLIRDSLHYKQL 52
           F    +I  +++ DSL+Y++L
Sbjct: 263 FTVILMIAFSILLDSLYYQKL 283


>UniRef50_P52387 Cluster: Virion protein U50; n=6; Roseolovirus|Rep:
           Virion protein U50 - Human herpesvirus 6A (strain
           Uganda-1102) (HHV-6 variant A) (Human Blymphotropic
           virus)
          Length = 555

 Score = 32.7 bits (71), Expect = 8.8
 Identities = 24/85 (28%), Positives = 42/85 (49%)
 Frame = -2

Query: 366 LHGLIFSSVFFFRTHSTVRCEVSNNALSQVVNESYLKNFILSNLVGLFSSVSKNVMIPIL 187
           LHG I + V  + T+  +R ++ NN    + ++ YL+    S LV + S         + 
Sbjct: 327 LHGAIKNDVLVYWTYQLMRPKLGNNVPIFIHDQHYLR----SGLVAIES---------LF 373

Query: 186 YMWPAIVSQSLISQRIQPVLLTCFF 112
            +W  + S+SL ++R+   LLT  F
Sbjct: 374 LLWRILNSESLFNKRVGKFLLTSIF 398


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 659,235,496
Number of Sequences: 1657284
Number of extensions: 12762146
Number of successful extensions: 34071
Number of sequences better than 10.0: 104
Number of HSP's better than 10.0 without gapping: 32821
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 33997
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 54545459628
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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