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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= NV120513.Seq
         (624 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_P40320 Cluster: S-adenosylmethionine synthetase; n=19; ...   157   2e-37
UniRef50_Q00266 Cluster: S-adenosylmethionine synthetase isoform...   146   4e-34
UniRef50_Q8MU02 Cluster: Putative S-adenosylmethionine synthetas...   135   7e-31
UniRef50_P19358 Cluster: S-adenosylmethionine synthetase 2; n=65...   131   1e-29
UniRef50_Q29NR2 Cluster: GA15421-PA; n=3; Bilateria|Rep: GA15421...   128   8e-29
UniRef50_Q9K7Q9 Cluster: S-adenosylmethionine synthetase; n=65; ...    93   4e-18
UniRef50_Q837P9 Cluster: S-adenosylmethionine synthetase; n=45; ...    93   5e-18
UniRef50_P0A820 Cluster: S-adenosylmethionine synthetase; n=23; ...    93   6e-18
UniRef50_A7APP7 Cluster: S-adenosylmethionine synthetase, putati...    90   3e-17
UniRef50_A7NSM8 Cluster: Chromosome chr18 scaffold_1, whole geno...    88   2e-16
UniRef50_P72871 Cluster: S-adenosylmethionine synthetase; n=119;...    87   2e-16
UniRef50_Q650L4 Cluster: S-adenosylmethionine synthetase; n=19; ...    77   5e-13
UniRef50_Q2U8T6 Cluster: S-adenosylmethionine synthetase; n=2; A...    73   4e-12
UniRef50_A4QEH8 Cluster: Putative uncharacterized protein; n=1; ...    73   6e-12
UniRef50_Q4A5F4 Cluster: S-adenosylmethionine synthetase; n=4; B...    72   1e-11
UniRef50_Q7QWJ4 Cluster: S-adenosylmethionine synthetase; n=1; G...    71   3e-11
UniRef50_Q1GND0 Cluster: S-adenosylmethionine synthetase; n=29; ...    69   7e-11
UniRef50_Q661P3 Cluster: S-adenosylmethionine synthetase; n=3; B...    67   3e-10
UniRef50_Q6KHY1 Cluster: S-adenosylmethionine synthetase; n=7; M...    65   1e-09
UniRef50_Q7NB16 Cluster: S-adenosylmethionine synthetase; n=2; M...    64   3e-09
UniRef50_A6BGC6 Cluster: S-adenosylmethionine synthetase; n=1; D...    62   1e-08
UniRef50_Q60BL6 Cluster: S-adenosylmethionine synthetase; n=6; B...    60   3e-08
UniRef50_Q2LSR0 Cluster: S-adenosylmethionine synthetase; n=1; S...    60   4e-08
UniRef50_O09486 Cluster: S-adenosylmethionine synthetase; n=1; A...    60   6e-08
UniRef50_Q2GDS4 Cluster: S-adenosylmethionine synthetase; n=1; N...    58   2e-07
UniRef50_Q5FGR4 Cluster: S-adenosylmethionine synthetase; n=13; ...    57   3e-07
UniRef50_UPI00015BD1C2 Cluster: UPI00015BD1C2 related cluster; n...    57   4e-07
UniRef50_Q6SZ22 Cluster: S-adenosylmethionine synthetase; n=4; S...    56   5e-07
UniRef50_A6QA94 Cluster: S-adenosylmethionine synthetase; n=20; ...    56   5e-07
UniRef50_P78003 Cluster: S-adenosylmethionine synthetase; n=4; M...    56   5e-07
UniRef50_Q1VNA9 Cluster: S-adenosylmethionine synthetase; n=1; P...    48   2e-04
UniRef50_A6PKG8 Cluster: Methionine adenosyltransferase precurso...    47   4e-04
UniRef50_Q6A7D8 Cluster: S-adenosylmethionine synthetase; n=11; ...    45   0.001
UniRef50_Q95QX7 Cluster: Putative uncharacterized protein; n=1; ...    44   0.002
UniRef50_Q7R6Z1 Cluster: Putative uncharacterized protein PY0779...    44   0.003
UniRef50_Q027Y1 Cluster: Methionine adenosyltransferase; n=1; So...    38   0.20 
UniRef50_A4DEX8 Cluster: Putative uncharacterized protein; n=1; ...    38   0.20 
UniRef50_UPI0000ECA413 Cluster: Endothelial cell-selective adhes...    36   1.0  
UniRef50_Q8FXU7 Cluster: Protease, putative; n=6; Brucellaceae|R...    35   1.4  
UniRef50_Q8ETA1 Cluster: Hypothetical conserved protein; n=1; Oc...    35   1.4  
UniRef50_A6RT45 Cluster: Putative uncharacterized protein; n=2; ...    34   2.4  
UniRef50_UPI00006A2011 Cluster: Tumor necrosis factor receptor s...    34   3.2  
UniRef50_Q15TP8 Cluster: Adenosine deaminase; n=2; Gammaproteoba...    34   3.2  
UniRef50_A4A0G4 Cluster: DNA-binding protein; n=1; Blastopirellu...    33   4.2  
UniRef50_A7SQA7 Cluster: Predicted protein; n=1; Nematostella ve...    33   4.2  
UniRef50_Q4QGM3 Cluster: Putative uncharacterized protein; n=3; ...    33   5.6  
UniRef50_UPI0000498BC3 Cluster: conserved hypothetical protein; ...    33   7.3  
UniRef50_Q1LVK4 Cluster: Novel fork head domain containing prote...    33   7.3  
UniRef50_A7MES0 Cluster: Putative uncharacterized protein; n=1; ...    33   7.3  
UniRef50_A0NE72 Cluster: ENSANGP00000030279; n=1; Anopheles gamb...    33   7.3  
UniRef50_Q4SDE4 Cluster: Chromosome 3 SCAF14639, whole genome sh...    32   9.7  

>UniRef50_P40320 Cluster: S-adenosylmethionine synthetase; n=19;
           Eukaryota|Rep: S-adenosylmethionine synthetase -
           Drosophila melanogaster (Fruit fly)
          Length = 408

 Score =  157 bits (382), Expect = 2e-37
 Identities = 71/83 (85%), Positives = 79/83 (95%)
 Frame = +1

Query: 259 KTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAG 438
           KTGM+LLCGEITSKA VDYQKVVRETV+HIGYDDSSKGFD+KTC+V+LALDQQSP IAAG
Sbjct: 72  KTGMILLCGEITSKAVVDYQKVVRETVQHIGYDDSSKGFDFKTCNVLLALDQQSPEIAAG 131

Query: 439 VHENRNDEEVGAGDQGLMFGYAT 507
           VH NR +EE+GAGDQG+MFGYAT
Sbjct: 132 VHVNRAEEEIGAGDQGIMFGYAT 154



 Score =  113 bits (271), Expect = 4e-24
 Identities = 51/62 (82%), Positives = 55/62 (88%)
 Frame = +2

Query: 77  NGYAKTNGHSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETK 256
           NG   +NG+SYDMEDG+ FLFTSESVGEGHPDKMCDQISDAILDAHL QDP+AKVACET 
Sbjct: 11  NGCNGSNGNSYDMEDGATFLFTSESVGEGHPDKMCDQISDAILDAHLKQDPNAKVACETV 70

Query: 257 LK 262
            K
Sbjct: 71  AK 72



 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 26/38 (68%), Positives = 28/38 (73%)
 Frame = +3

Query: 483 GLDVRLCNSETEECMPLTVVLAHKLNPKIAELRRNGEF 596
           G+       ETEECMPLTVVLAHKLN KIAELRR+  F
Sbjct: 147 GIMFGYATDETEECMPLTVVLAHKLNEKIAELRRSDVF 184


>UniRef50_Q00266 Cluster: S-adenosylmethionine synthetase isoform
           type-1; n=171; cellular organisms|Rep:
           S-adenosylmethionine synthetase isoform type-1 - Homo
           sapiens (Human)
          Length = 395

 Score =  146 bits (354), Expect = 4e-34
 Identities = 65/83 (78%), Positives = 78/83 (93%)
 Frame = +1

Query: 259 KTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAG 438
           KTGMVLLCGEITS A VDYQ+VVR+T+KHIGYDDS+KGFD+KTC+V++AL+QQSP+IA  
Sbjct: 61  KTGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQC 120

Query: 439 VHENRNDEEVGAGDQGLMFGYAT 507
           VH +RN+E+VGAGDQGLMFGYAT
Sbjct: 121 VHLDRNEEDVGAGDQGLMFGYAT 143



 Score = 88.2 bits (209), Expect = 1e-16
 Identities = 39/52 (75%), Positives = 46/52 (88%)
 Frame = +2

Query: 107 YDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKLK 262
           + + +G VF+FTSESVGEGHPDK+CDQISDA+LDAHL QDP+AKVACET  K
Sbjct: 11  HSLSEG-VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCK 61



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 22/36 (61%), Positives = 28/36 (77%)
 Frame = +3

Query: 483 GLDVRLCNSETEECMPLTVVLAHKLNPKIAELRRNG 590
           GL       ETEECMPLT++LAHKLN ++A+LRR+G
Sbjct: 136 GLMFGYATDETEECMPLTIILAHKLNARMADLRRSG 171


>UniRef50_Q8MU02 Cluster: Putative S-adenosylmethionine synthetase;
           n=1; Heterodera glycines|Rep: Putative
           S-adenosylmethionine synthetase - Heterodera glycines
           (Soybean cyst nematode worm)
          Length = 211

 Score =  135 bits (327), Expect = 7e-31
 Identities = 60/82 (73%), Positives = 72/82 (87%)
 Frame = +1

Query: 256 TKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAA 435
           TKTGMVL+CGE TS A VDYQ VVRET+K IGYDDSSKGF+YKTC+V++AL++QSP IAA
Sbjct: 97  TKTGMVLVCGETTSSATVDYQSVVRETIKKIGYDDSSKGFNYKTCNVLVALEKQSPEIAA 156

Query: 436 GVHENRNDEEVGAGDQGLMFGY 501
           GVHE++  E+VGA DQG+MF Y
Sbjct: 157 GVHEDKEPEDVGARDQGIMFXY 178



 Score = 83.0 bits (196), Expect = 5e-15
 Identities = 39/49 (79%), Positives = 39/49 (79%)
 Frame = +2

Query: 116 EDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKLK 262
           E    FLFTSESVGEGHPDKMCDQISDAILDAHL  DP AKVACE   K
Sbjct: 50  EQVGTFLFTSESVGEGHPDKMCDQISDAILDAHLALDPAAKVACEVVTK 98



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 18/38 (47%), Positives = 25/38 (65%)
 Frame = +3

Query: 474 RRPGLDVRLCNSETEECMPLTVVLAHKLNPKIAELRRN 587
           R  G+     + E+ E MPLT+VL+HKLN K  +LRR+
Sbjct: 170 RDQGIMFXYPSDESPEAMPLTLVLSHKLNAKYHQLRRS 207


>UniRef50_P19358 Cluster: S-adenosylmethionine synthetase 2; n=659;
           cellular organisms|Rep: S-adenosylmethionine synthetase
           2 - Saccharomyces cerevisiae (Baker's yeast)
          Length = 384

 Score =  131 bits (317), Expect = 1e-29
 Identities = 54/83 (65%), Positives = 76/83 (91%)
 Frame = +1

Query: 259 KTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAG 438
           KTGM+++ GEIT+KA +DYQ++VR+T+K IGYDDS+KGFDYKTC+V++A++QQSP+IA G
Sbjct: 50  KTGMIMVFGEITTKARLDYQQIVRDTIKKIGYDDSAKGFDYKTCNVLVAIEQQSPDIAQG 109

Query: 439 VHENRNDEEVGAGDQGLMFGYAT 507
           +H  ++ E++GAGDQG+MFGYAT
Sbjct: 110 LHYEKSLEDLGAGDQGIMFGYAT 132



 Score = 81.8 bits (193), Expect = 1e-14
 Identities = 37/50 (74%), Positives = 40/50 (80%)
 Frame = +2

Query: 113 MEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKLK 262
           M     FLFTSESVGEGHPDK+CDQ+SDAILDA L QDP +KVACET  K
Sbjct: 1   MSKSKTFLFTSESVGEGHPDKICDQVSDAILDACLEQDPFSKVACETAAK 50



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 17/36 (47%), Positives = 24/36 (66%)
 Frame = +3

Query: 483 GLDVRLCNSETEECMPLTVVLAHKLNPKIAELRRNG 590
           G+       ET E +PLT++LAHKLN  +A+ RR+G
Sbjct: 125 GIMFGYATDETPEGLPLTILLAHKLNMAMADARRDG 160


>UniRef50_Q29NR2 Cluster: GA15421-PA; n=3; Bilateria|Rep: GA15421-PA
           - Drosophila pseudoobscura (Fruit fly)
          Length = 200

 Score =  128 bits (310), Expect = 8e-29
 Identities = 59/83 (71%), Positives = 73/83 (87%)
 Frame = +1

Query: 259 KTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAG 438
           KTGM+LLCGEITSKA VDYQKVVRETV+HIGYDDSSKGFD+KT ++++A++QQSP+IA G
Sbjct: 72  KTGMILLCGEITSKAVVDYQKVVRETVQHIGYDDSSKGFDWKTLNLLVAIEQQSPDIANG 131

Query: 439 VHENRNDEEVGAGDQGLMFGYAT 507
           VH NR +++VGAGDQ  +   AT
Sbjct: 132 VHINREEDDVGAGDQVSILKRAT 154



 Score =  112 bits (270), Expect = 6e-24
 Identities = 51/62 (82%), Positives = 54/62 (87%)
 Frame = +2

Query: 77  NGYAKTNGHSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETK 256
           NG   +NG+SYDMEDG  FLFTSESVGEGHPDKMCDQISDAILDAHL QDP+AKVACET 
Sbjct: 11  NGCNGSNGNSYDMEDGQTFLFTSESVGEGHPDKMCDQISDAILDAHLKQDPNAKVACETV 70

Query: 257 LK 262
            K
Sbjct: 71  AK 72


>UniRef50_Q9K7Q9 Cluster: S-adenosylmethionine synthetase; n=65;
           cellular organisms|Rep: S-adenosylmethionine synthetase
           - Bacillus halodurans
          Length = 399

 Score = 93.5 bits (222), Expect = 4e-18
 Identities = 49/106 (46%), Positives = 71/106 (66%), Gaps = 10/106 (9%)
 Frame = +1

Query: 217 ESGSGRKSCM*NQTKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSV 396
           E  + R +C  + T TG+VL+ GEIT+   VD  KVVR+T+++IGY  +  GFD +TC+V
Sbjct: 38  EDPNARVACETSVT-TGLVLVAGEITTSTYVDIPKVVRDTIRNIGYTRAKYGFDSETCAV 96

Query: 397 MLALDQQSPNIAAGVHE----------NRNDEEVGAGDQGLMFGYA 504
           + ++D+QSP+IA GV++          +   E +GAGDQGLMFGYA
Sbjct: 97  LTSIDEQSPDIAQGVNQALEAREGQMTDAEIEAIGAGDQGLMFGYA 142



 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 31/42 (73%), Positives = 37/42 (88%)
 Frame = +2

Query: 134 LFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKL 259
           LFTSESV EGHPDK+CDQISD+ILD  L +DP+A+VACET +
Sbjct: 9   LFTSESVTEGHPDKICDQISDSILDEILKEDPNARVACETSV 50



 Score = 33.5 bits (73), Expect = 4.2
 Identities = 15/34 (44%), Positives = 22/34 (64%)
 Frame = +3

Query: 483 GLDVRLCNSETEECMPLTVVLAHKLNPKIAELRR 584
           GL     N+ET E MPL + L+HKL  +++E R+
Sbjct: 136 GLMFGYANNETPELMPLPISLSHKLARRLSEARK 169


>UniRef50_Q837P9 Cluster: S-adenosylmethionine synthetase; n=45;
           cellular organisms|Rep: S-adenosylmethionine synthetase
           - Enterococcus faecalis (Streptococcus faecalis)
          Length = 394

 Score = 93.1 bits (221), Expect = 5e-18
 Identities = 48/87 (55%), Positives = 66/87 (75%), Gaps = 6/87 (6%)
 Frame = +1

Query: 262 TGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGV 441
           TG+VL+ GEI++ A VD QK+VR+TVK IGY  +  GFD +T +V++A+D+QSP+IA GV
Sbjct: 49  TGLVLVFGEISTTAYVDIQKIVRQTVKDIGYTRAKYGFDGETVAVLVAIDEQSPDIAQGV 108

Query: 442 H---ENRNDEE---VGAGDQGLMFGYA 504
               E R+ +E   +GAGDQGLMFG+A
Sbjct: 109 DAALEVRDQDEKDDIGAGDQGLMFGFA 135



 Score = 69.3 bits (162), Expect = 7e-11
 Identities = 31/42 (73%), Positives = 36/42 (85%)
 Frame = +2

Query: 134 LFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKL 259
           LFTSESV EGHPDK+ DQ+SDAILDA L +DP A+VACET +
Sbjct: 6   LFTSESVSEGHPDKVADQVSDAILDAILEKDPMARVACETSV 47



 Score = 32.3 bits (70), Expect = 9.7
 Identities = 15/34 (44%), Positives = 21/34 (61%)
 Frame = +3

Query: 483 GLDVRLCNSETEECMPLTVVLAHKLNPKIAELRR 584
           GL       ET E MPL + L+H+L  ++AELR+
Sbjct: 129 GLMFGFAVDETPELMPLPIALSHRLVRRLAELRK 162


>UniRef50_P0A820 Cluster: S-adenosylmethionine synthetase; n=23;
           Proteobacteria|Rep: S-adenosylmethionine synthetase -
           Shigella flexneri
          Length = 384

 Score = 92.7 bits (220), Expect = 6e-18
 Identities = 46/83 (55%), Positives = 60/83 (72%)
 Frame = +1

Query: 259 KTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAG 438
           KTGMVL+ GEIT+ A VD +++ R TV+ IGY  S  GFD  +C+V+ A+ +QSP+I  G
Sbjct: 47  KTGMVLVGGEITTSAWVDIEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPDINQG 106

Query: 439 VHENRNDEEVGAGDQGLMFGYAT 507
           V +  +  E GAGDQGLMFGYAT
Sbjct: 107 V-DRADPLEQGAGDQGLMFGYAT 128



 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 33/43 (76%), Positives = 37/43 (86%)
 Frame = +2

Query: 134 LFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKLK 262
           LFTSESV EGHPDK+ DQISDA+LDA L QDP A+VACET +K
Sbjct: 5   LFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVK 47


>UniRef50_A7APP7 Cluster: S-adenosylmethionine synthetase, putative;
           n=1; Babesia bovis|Rep: S-adenosylmethionine synthetase,
           putative - Babesia bovis
          Length = 416

 Score = 90.2 bits (214), Expect = 3e-17
 Identities = 42/80 (52%), Positives = 55/80 (68%)
 Frame = +1

Query: 268 MVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVHE 447
           +V++ GEIT+ A VDYQ VVR+ +  IGY  +  GFD  T  +M+ L QQ+P IA+ VH 
Sbjct: 60  LVMVFGEITTNAVVDYQAVVRQVLTDIGYTSNELGFDASTVEIMVRLAQQAPEIASAVHL 119

Query: 448 NRNDEEVGAGDQGLMFGYAT 507
            R  EE  AGDQG+MFGYA+
Sbjct: 120 GRKLEETAAGDQGIMFGYAS 139



 Score = 79.0 bits (186), Expect = 9e-14
 Identities = 36/47 (76%), Positives = 40/47 (85%)
 Frame = +2

Query: 110 DMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 250
           D  D + FLFTSESV EGHPDK+CDQISDAILDA L QDP++KVACE
Sbjct: 7   DTVDKNNFLFTSESVNEGHPDKICDQISDAILDACLRQDPESKVACE 53


>UniRef50_A7NSM8 Cluster: Chromosome chr18 scaffold_1, whole genome
           shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
           chr18 scaffold_1, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 509

 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 43/84 (51%), Positives = 57/84 (67%)
 Frame = +1

Query: 256 TKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAA 435
           TKT MV++ GEIT+KAN+DY+K+VR+T + IG+     GFD   C V++ + QQSPNI  
Sbjct: 284 TKTDMVMIFGEITTKANIDYEKIVRDTCRTIGFVFYDVGFDVDNCKVLVNIGQQSPNITQ 343

Query: 436 GVHENRNDEEVGAGDQGLMFGYAT 507
            V      + + AGDQG MFGYAT
Sbjct: 344 DV------QGISAGDQGHMFGYAT 361



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 24/43 (55%), Positives = 29/43 (67%)
 Frame = +2

Query: 134 LFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKLK 262
           L+  E V  GH  ++   ISDA+LDA L QDPD+KVACET  K
Sbjct: 243 LYYMEDVSIGHVHQIQSDISDAVLDACLTQDPDSKVACETCTK 285


>UniRef50_P72871 Cluster: S-adenosylmethionine synthetase; n=119;
           Bacteria|Rep: S-adenosylmethionine synthetase -
           Synechocystis sp. (strain PCC 6803)
          Length = 426

 Score = 87.4 bits (207), Expect = 2e-16
 Identities = 41/90 (45%), Positives = 65/90 (72%), Gaps = 9/90 (10%)
 Frame = +1

Query: 262 TGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGV 441
           TG+ L+ GEITS+A++++ +++R+ +  IGY ++  G+   +C+VMLA+D+QSP+I+ GV
Sbjct: 55  TGLTLVTGEITSQAHINFVELIRQKIAEIGYTNADNGYSANSCAVMLAIDEQSPDISQGV 114

Query: 442 -------HENRNDE--EVGAGDQGLMFGYA 504
                  H   +DE  ++GAGDQGLMFGYA
Sbjct: 115 TAAQEQRHALSDDELDKIGAGDQGLMFGYA 144



 Score = 67.3 bits (157), Expect = 3e-10
 Identities = 30/41 (73%), Positives = 35/41 (85%)
 Frame = +2

Query: 131 FLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACET 253
           +LFTSESV EGHPDK+CDQISD ILDA L  DP+++VA ET
Sbjct: 11  YLFTSESVTEGHPDKVCDQISDTILDALLTLDPNSRVAAET 51



 Score = 34.3 bits (75), Expect = 2.4
 Identities = 14/31 (45%), Positives = 24/31 (77%)
 Frame = +3

Query: 501 CNSETEECMPLTVVLAHKLNPKIAELRRNGE 593
           CN ET E MPL + LAH++  +++E+R++G+
Sbjct: 145 CN-ETPELMPLPISLAHRIALRLSEVRKSGQ 174


>UniRef50_Q650L4 Cluster: S-adenosylmethionine synthetase; n=19;
           cellular organisms|Rep: S-adenosylmethionine synthetase
           - Bacteroides fragilis
          Length = 430

 Score = 76.6 bits (180), Expect = 5e-13
 Identities = 38/87 (43%), Positives = 53/87 (60%)
 Frame = +1

Query: 262 TGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGV 441
           TG V+L GE+ + A VD Q + RE ++ IGY      F+  +C V+ A+ +QS +I  GV
Sbjct: 47  TGQVVLAGEVKTGAYVDLQLIAREVIQKIGYTKGEYMFESNSCGVLSAIHEQSADINRGV 106

Query: 442 HENRNDEEVGAGDQGLMFGYATVRQKN 522
            E  +    GAGDQG+MFGYAT   +N
Sbjct: 107 -EREDPMNQGAGDQGMMFGYATNETEN 132



 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 30/41 (73%), Positives = 34/41 (82%)
 Frame = +2

Query: 131 FLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACET 253
           +LFTSESV EGHPDK+ DQISDA+LD  L  DP +KVACET
Sbjct: 3   YLFTSESVSEGHPDKVADQISDAVLDKLLAYDPSSKVACET 43


>UniRef50_Q2U8T6 Cluster: S-adenosylmethionine synthetase; n=2;
           Ascomycota|Rep: S-adenosylmethionine synthetase -
           Aspergillus oryzae
          Length = 384

 Score = 73.3 bits (172), Expect = 4e-12
 Identities = 33/51 (64%), Positives = 41/51 (80%)
 Frame = +2

Query: 113 MEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKLKP 265
           M+  S FLFTSESVGEGHPDK+CDQ++DAILD  L Q+P +KVA E  ++P
Sbjct: 1   MKSQSKFLFTSESVGEGHPDKICDQVADAILDECLKQNPLSKVAIEVAVRP 51



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 28/84 (33%), Positives = 46/84 (54%), Gaps = 1/84 (1%)
 Frame = +1

Query: 259 KTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAG 438
           + G+V++ G +     +D   +VR  +K IGY    +  DY+TC VM  ++   P++  G
Sbjct: 50  RPGLVIVFGVVHFIPQLDIDAIVRFVLKDIGYTSPDQELDYRTCQVMDCVELH-PSLFNG 108

Query: 439 VHEN-RNDEEVGAGDQGLMFGYAT 507
           +       ++  AGDQG+ FGYAT
Sbjct: 109 ISSGLEAPDDEPAGDQGMAFGYAT 132


>UniRef50_A4QEH8 Cluster: Putative uncharacterized protein; n=1;
           Corynebacterium glutamicum R|Rep: Putative
           uncharacterized protein - Corynebacterium glutamicum
           (strain R)
          Length = 257

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 38/91 (41%), Positives = 55/91 (60%), Gaps = 9/91 (9%)
 Frame = +1

Query: 262 TGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGV 441
           TG+V + GE+ + A V+  ++VR  +  IG++ S  GFD +TC V +++ +QS  IA GV
Sbjct: 52  TGIVHVVGEVRTSAYVEIPQLVRNKLIEIGFNSSEVGFDGRTCGVSVSIGEQSQEIADGV 111

Query: 442 HEN---------RNDEEVGAGDQGLMFGYAT 507
             +           D+  GAGDQGLMFGYAT
Sbjct: 112 DNSDEARTNGDVEEDDRAGAGDQGLMFGYAT 142



 Score = 64.9 bits (151), Expect = 1e-09
 Identities = 30/43 (69%), Positives = 35/43 (81%)
 Frame = +2

Query: 125 SVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACET 253
           +V LFTSESV EGHPDK+CD ISD ILDA L +DP ++VA ET
Sbjct: 6   AVRLFTSESVTEGHPDKICDAISDTILDALLEKDPQSRVAVET 48



 Score = 36.7 bits (81), Expect = 0.45
 Identities = 15/36 (41%), Positives = 24/36 (66%)
 Frame = +3

Query: 483 GLDVRLCNSETEECMPLTVVLAHKLNPKIAELRRNG 590
           GL      +ETEE MPL + LAH+L+ ++ ++R+ G
Sbjct: 135 GLMFGYATNETEEYMPLPIALAHRLSRRLTQVRKEG 170


>UniRef50_Q4A5F4 Cluster: S-adenosylmethionine synthetase; n=4;
           Bacteria|Rep: S-adenosylmethionine synthetase -
           Mycoplasma synoviae (strain 53)
          Length = 382

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 35/58 (60%), Positives = 41/58 (70%)
 Frame = +2

Query: 134 LFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKLKPVWCFCVAKSHPKLT 307
           LFTSESVG GHPDK+CDQISDAILDA+L  DP +KVA ET +     F   +   K+T
Sbjct: 4   LFTSESVGRGHPDKICDQISDAILDAYLTWDPHSKVAVETMVSGNNVFIAGEVKSKVT 61



 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 31/79 (39%), Positives = 47/79 (59%)
 Frame = +1

Query: 271 VLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVHEN 450
           V + GE+ SK  VD  ++ +  +++IGY  ++  F       +  +  QS NIA GV+  
Sbjct: 50  VFIAGEVKSKVTVDVIEIAKNVLRNIGYYSNNTSF-------ITDIKSQSENIAMGVNLQ 102

Query: 451 RNDEEVGAGDQGLMFGYAT 507
            +D+ +GAGDQG MFGYAT
Sbjct: 103 DSDD-LGAGDQGFMFGYAT 120


>UniRef50_Q7QWJ4 Cluster: S-adenosylmethionine synthetase; n=1;
           Giardia lamblia ATCC 50803|Rep: S-adenosylmethionine
           synthetase - Giardia lamblia ATCC 50803
          Length = 436

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 34/87 (39%), Positives = 52/87 (59%)
 Frame = +1

Query: 259 KTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAG 438
           K   V L GEI++ A VDY ++VR+ ++ IGY+D     D++T  ++  +  QSP+I   
Sbjct: 53  KDNTVFLLGEISTTAVVDYNQIVRDVLREIGYEDEKTSCDWRTVEIINRISSQSPDIYQA 112

Query: 439 VHENRNDEEVGAGDQGLMFGYATVRQK 519
           V      +E+ AGDQG+M GYA+   K
Sbjct: 113 VF---RQDELCAGDQGIMIGYASQETK 136



 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 29/44 (65%), Positives = 33/44 (75%)
 Frame = +2

Query: 131 FLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKLK 262
           FLFTSE V EGHPDK+CDQISD ILD  L QD  A+VA +  +K
Sbjct: 10  FLFTSEQVSEGHPDKICDQISDRILDTILAQDKIARVAADVAIK 53


>UniRef50_Q1GND0 Cluster: S-adenosylmethionine synthetase; n=29;
           Alphaproteobacteria|Rep: S-adenosylmethionine synthetase
           - Sphingopyxis alaskensis (Sphingomonas alaskensis)
          Length = 406

 Score = 69.3 bits (162), Expect = 7e-11
 Identities = 30/41 (73%), Positives = 36/41 (87%)
 Frame = +2

Query: 131 FLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACET 253
           FLFTSESV EGHPDK+ DQISD+I+D  L +DP+A+VACET
Sbjct: 5   FLFTSESVSEGHPDKVADQISDSIVDLFLAKDPEARVACET 45



 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 33/75 (44%), Positives = 42/75 (56%)
 Frame = +1

Query: 283 GEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVHENRNDE 462
           GE    A  + +  VR TV+ IGY+ +  GF +        L  QSP IA GV E    +
Sbjct: 67  GEWAPGALDEIEATVRRTVREIGYEQA--GFHWNRFRFENNLHGQSPQIAQGVDEGAGKD 124

Query: 463 EVGAGDQGLMFGYAT 507
           E GAGDQG+MFGYA+
Sbjct: 125 E-GAGDQGIMFGYAS 138


>UniRef50_Q661P3 Cluster: S-adenosylmethionine synthetase; n=3;
           Borrelia burgdorferi group|Rep: S-adenosylmethionine
           synthetase - Borrelia garinii
          Length = 392

 Score = 67.3 bits (157), Expect = 3e-10
 Identities = 33/87 (37%), Positives = 54/87 (62%), Gaps = 2/87 (2%)
 Frame = +1

Query: 268 MVLLCGEITS--KANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGV 441
           +V++ GEI S  K  +D +++ ++ +K IGY +   G DYKT +V+ A+  QS +I   +
Sbjct: 55  LVVIAGEINSPVKKTLDIKEIAKKIIKDIGYTNIDYGLDYKTITVIDAIGNQSQDIINAI 114

Query: 442 HENRNDEEVGAGDQGLMFGYATVRQKN 522
            + +    +GAGDQG++FGYA    KN
Sbjct: 115 -KKKGSNALGAGDQGIIFGYACDETKN 140



 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 27/37 (72%), Positives = 30/37 (81%)
 Frame = +2

Query: 140 TSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 250
           TSE+V EGHPDK+ DQISDAILD  L  D +AKVACE
Sbjct: 12  TSEAVSEGHPDKIADQISDAILDEILKVDKNAKVACE 48


>UniRef50_Q6KHY1 Cluster: S-adenosylmethionine synthetase; n=7;
           Mycoplasma|Rep: S-adenosylmethionine synthetase -
           Mycoplasma mobile
          Length = 386

 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 28/39 (71%), Positives = 35/39 (89%)
 Frame = +2

Query: 134 LFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 250
           +FTSESVG+GHPDK+CDQISD ILD+ L +D +A+VACE
Sbjct: 5   IFTSESVGKGHPDKICDQISDRILDSILKKDCNARVACE 43



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 24/80 (30%), Positives = 51/80 (63%)
 Frame = +1

Query: 268 MVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVHE 447
           ++++ GEI + + +D  K     +  +GYD++    D+   +++  +++QS +I+ GV  
Sbjct: 50  LIVIGGEIKTNSYIDVVKEAWNILLKLGYDEN----DF---TIISNINKQSSDISFGV-- 100

Query: 448 NRNDEEVGAGDQGLMFGYAT 507
           ++++  + AGDQG++FGYAT
Sbjct: 101 DKSNGSIAAGDQGIVFGYAT 120


>UniRef50_Q7NB16 Cluster: S-adenosylmethionine synthetase; n=2;
           Mycoplasmataceae|Rep: S-adenosylmethionine synthetase -
           Mycoplasma gallisepticum
          Length = 395

 Score = 63.7 bits (148), Expect = 3e-09
 Identities = 30/60 (50%), Positives = 41/60 (68%)
 Frame = +2

Query: 71  KMNGYAKTNGHSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 250
           K+ GY   N    ++      ++T+ESVG  HPDK+CDQI+DAILDA L QD +++VACE
Sbjct: 3   KIKGYFTLN--IINLNHNRKGVYTAESVGSAHPDKLCDQIADAILDACLKQDQNSRVACE 60



 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 31/85 (36%), Positives = 51/85 (60%)
 Frame = +1

Query: 268 MVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVHE 447
           ++++ GEI++KA+VDY     + V   GYD S    D+   +++  ++QQS  IA  V  
Sbjct: 67  LIIIAGEISTKASVDYVGTAWKVVNQFGYDRS----DF---TIIANINQQSSEIAQSV-- 117

Query: 448 NRNDEEVGAGDQGLMFGYATVRQKN 522
           ++ + ++GAGDQG+  GYA    KN
Sbjct: 118 DQKNHKIGAGDQGITVGYACDETKN 142


>UniRef50_A6BGC6 Cluster: S-adenosylmethionine synthetase; n=1;
           Dorea longicatena DSM 13814|Rep: S-adenosylmethionine
           synthetase - Dorea longicatena DSM 13814
          Length = 387

 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 26/38 (68%), Positives = 32/38 (84%)
 Frame = +2

Query: 137 FTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 250
           +T+ESV EGHPDK+CDQI+DAILD  L  DP ++VACE
Sbjct: 6   YTAESVTEGHPDKVCDQIADAILDECLRYDPSSRVACE 43



 Score = 39.9 bits (89), Expect = 0.048
 Identities = 35/103 (33%), Positives = 49/103 (47%), Gaps = 10/103 (9%)
 Frame = +1

Query: 226 SGRKSCM*NQTKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLA 405
           S R +C    T+ G V + GEITS        V+R+ ++  GY   + G +  T      
Sbjct: 37  SSRVACEVLATR-GNVFVAGEITSGYEPPVFDVIRKVLEECGY--CTDGIEMDTF----- 88

Query: 406 LDQQSPNIAAGVHENRN----------DEEVGAGDQGLMFGYA 504
           + QQSP+IA  V  ++           D   GAGDQG+M GYA
Sbjct: 89  VHQQSPDIAKAVSVSKEFRDNIGAKLRDRSRGAGDQGVMVGYA 131


>UniRef50_Q60BL6 Cluster: S-adenosylmethionine synthetase; n=6;
           Bacteria|Rep: S-adenosylmethionine synthetase -
           Methylococcus capsulatus
          Length = 397

 Score = 60.5 bits (140), Expect = 3e-08
 Identities = 29/53 (54%), Positives = 35/53 (66%)
 Frame = +2

Query: 131 FLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKLKPVWCFCVAK 289
           FLFTSE+V EGHPD +CD ISDA++D  L QDP A+V  E  L     F  A+
Sbjct: 5   FLFTSEAVTEGHPDCVCDIISDAVVDRFLQQDPYARVVTECALSKSVVFLAAR 57


>UniRef50_Q2LSR0 Cluster: S-adenosylmethionine synthetase; n=1;
           Syntrophus aciditrophicus SB|Rep: S-adenosylmethionine
           synthetase - Syntrophus aciditrophicus (strain SB)
          Length = 392

 Score = 60.1 bits (139), Expect = 4e-08
 Identities = 27/81 (33%), Positives = 50/81 (61%), Gaps = 1/81 (1%)
 Frame = +1

Query: 265 GMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVH 444
           G+ ++ GE+ ++  VD ++ VR+TV  +GY D   G +  +  ++  +  QSP+I  G  
Sbjct: 54  GLCIVGGEVATRIYVDIERCVRDTVLKLGYCDYELGLNGNSMGILNTIIPQSPDINIGTR 113

Query: 445 ENRND-EEVGAGDQGLMFGYA 504
            +    +E+GAGDQG+++G+A
Sbjct: 114 ADLGKYKEIGAGDQGIIYGFA 134


>UniRef50_O09486 Cluster: S-adenosylmethionine synthetase; n=1;
           Amoeba proteus|Rep: S-adenosylmethionine synthetase -
           Amoeba proteus (Amoeba)
          Length = 426

 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 37/92 (40%), Positives = 43/92 (46%), Gaps = 2/92 (2%)
 Frame = +1

Query: 259 KTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAG 438
           K  +V L GE+T +         RE V  IGY       D  TCSV + +  Q   I   
Sbjct: 54  KGNVVGLFGEVTCQKTFPTISWFRELVTEIGYSREDLDLDPTTCSVHINVRGQEAEIRGV 113

Query: 439 VH--ENRNDEEVGAGDQGLMFGYATVRQKNAC 528
           VH  E    E +GAGDQGLMFGYAT      C
Sbjct: 114 VHNQERAAKETLGAGDQGLMFGYATDETPERC 145



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 25/54 (46%), Positives = 33/54 (61%), Gaps = 4/54 (7%)
 Frame = +2

Query: 113 MEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAK----VACETKLK 262
           M+  + +LF SE+V  GHPDK CDQ+SD +LD  L  +   K    VA ET +K
Sbjct: 1   MQQNTRYLFASEAVSRGHPDKACDQVSDRVLDYCLQAEKKCKKASRVALETTIK 54


>UniRef50_Q2GDS4 Cluster: S-adenosylmethionine synthetase; n=1;
           Neorickettsia sennetsu str. Miyayama|Rep:
           S-adenosylmethionine synthetase - Neorickettsia sennetsu
           (strain Miyayama)
          Length = 382

 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 24/43 (55%), Positives = 33/43 (76%)
 Frame = +2

Query: 137 FTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKLKP 265
           F+SE+V  GHPDK+ DQISD +LD +L +DP ++VA ET + P
Sbjct: 8   FSSEAVLPGHPDKIADQISDLVLDTYLQKDPSSRVAAETMVTP 50



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 31/81 (38%), Positives = 49/81 (60%), Gaps = 2/81 (2%)
 Frame = +1

Query: 271 VLLCGEITSK--ANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVH 444
           V++ GEI      N + ++ +R  +K IGY+      D+++  ++  L +QSP I+AG+ 
Sbjct: 53  VIVAGEIYGPEVTNAELEEKIRLFLKGIGYEKHL--LDWESLEIVNLLHEQSPEISAGL- 109

Query: 445 ENRNDEEVGAGDQGLMFGYAT 507
             R    +GAGDQG+MFGYAT
Sbjct: 110 --RRSASLGAGDQGVMFGYAT 128


>UniRef50_Q5FGR4 Cluster: S-adenosylmethionine synthetase; n=13;
           Rickettsiales|Rep: S-adenosylmethionine synthetase -
           Ehrlichia ruminantium (strain Gardel)
          Length = 401

 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 31/81 (38%), Positives = 46/81 (56%), Gaps = 3/81 (3%)
 Frame = +1

Query: 271 VLLCGEITSKANVD---YQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGV 441
           V + GEI    NVD    Q + R  +K IGY+    GF ++   + + + +QSP+I  GV
Sbjct: 58  VFIAGEICG-VNVDNSIIQSIARSVIKEIGYEQD--GFHWENVDIEILIHEQSPDIIVGV 114

Query: 442 HENRNDEEVGAGDQGLMFGYA 504
           +   N    GAGDQG+++GYA
Sbjct: 115 NSGENQ---GAGDQGIVYGYA 132



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 24/43 (55%), Positives = 31/43 (72%)
 Frame = +2

Query: 125 SVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACET 253
           S ++ TSESV  GHPDK+ DQISDAILD +++ +P    A ET
Sbjct: 9   SSYIITSESVSSGHPDKIADQISDAILDYYISLNPFVHTAIET 51


>UniRef50_UPI00015BD1C2 Cluster: UPI00015BD1C2 related cluster; n=1;
           unknown|Rep: UPI00015BD1C2 UniRef100 entry - unknown
          Length = 372

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 29/82 (35%), Positives = 46/82 (56%)
 Frame = +1

Query: 262 TGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGV 441
           + +V + GE++S A VD Q V ++ +K +GY     GFD     V+ ++++QSP IA  +
Sbjct: 47  SNIVFIAGEVSSSAYVDLQIVSKKAIKEVGYTKPEYGFDGDLIGVISSINEQSPEIALCI 106

Query: 442 HENRNDEEVGAGDQGLMFGYAT 507
                    GAGD  ++ GYAT
Sbjct: 107 ASE------GAGDSAIVVGYAT 122



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 19/39 (48%), Positives = 26/39 (66%)
 Frame = +2

Query: 143 SESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKL 259
           +ES  EGHPDK+ D ISD ILD  + +DP ++V+    L
Sbjct: 7   AESPFEGHPDKLADIISDEILDEFMRKDPFSRVSINVLL 45


>UniRef50_Q6SZ22 Cluster: S-adenosylmethionine synthetase; n=4;
           Streptococcus|Rep: S-adenosylmethionine synthetase -
           Streptococcus pyogenes
          Length = 353

 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 25/47 (53%), Positives = 32/47 (68%)
 Frame = +2

Query: 122 GSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKLK 262
           G + + +SE V  GHPDK+CDQISDAIL   L  D  ++VA ET +K
Sbjct: 6   GGIMIISSEQVSVGHPDKICDQISDAILTECLKYDKSSRVAVETLIK 52



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 36/108 (33%), Positives = 50/108 (46%)
 Frame = +1

Query: 259 KTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAG 438
           K   V++ GEI+++   + + +VR+ V+ +G          K   V   L  QS +IA G
Sbjct: 52  KDNQVVVAGEISTRHYFNLENIVRQVVEPLGM---------KNVRVTNLLGLQSSDIAQG 102

Query: 439 VHENRNDEEVGAGDQGLMFGYATVRQKNACR*L*CLHTNSIRKLQSSG 582
           V         GAGDQG+MFGYAT            L T  + KL S G
Sbjct: 103 VDNG------GAGDQGMMFGYATDETPEYLPLPYVLATRVLEKLMSLG 144


>UniRef50_A6QA94 Cluster: S-adenosylmethionine synthetase; n=20;
           Epsilonproteobacteria|Rep: S-adenosylmethionine
           synthetase - Sulfurovum sp. (strain NBC37-1)
          Length = 405

 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 25/41 (60%), Positives = 32/41 (78%)
 Frame = +2

Query: 128 VFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 250
           ++LFTSESV  GHPDK  D I+D I+D+ L +DP+AKVA E
Sbjct: 1   MYLFTSESVSAGHPDKCADLIADTIVDSLLQRDPNAKVATE 41



 Score = 52.4 bits (120), Expect = 8e-06
 Identities = 32/86 (37%), Positives = 52/86 (60%), Gaps = 7/86 (8%)
 Frame = +1

Query: 271 VLLCGEI-TSKA--NVDYQKVVRETVKHIGYDDSS----KGFDYKTCSVMLALDQQSPNI 429
           +++ GE+ TS A  NV Y++  ++ ++ IGY +      + F      + + + +QSP+I
Sbjct: 49  IIIGGEVKTSTAVDNVFYEECAQKALEKIGYPEGGFKRGETFFPDEAEIEVYVSKQSPDI 108

Query: 430 AAGVHENRNDEEVGAGDQGLMFGYAT 507
             GV +  N  E+GAGDQG+MFGYAT
Sbjct: 109 TMGVVKEGN--EIGAGDQGMMFGYAT 132


>UniRef50_P78003 Cluster: S-adenosylmethionine synthetase; n=4;
           Mycoplasma|Rep: S-adenosylmethionine synthetase -
           Mycoplasma pneumoniae
          Length = 383

 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 22/38 (57%), Positives = 30/38 (78%)
 Frame = +2

Query: 137 FTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 250
           + +E+VG GHPDK+CDQI+D+ILD  + Q P + VACE
Sbjct: 13  YVAEAVGRGHPDKICDQIADSILDECIKQSPTSHVACE 50



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 24/79 (30%), Positives = 42/79 (53%)
 Frame = +1

Query: 268 MVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVHE 447
           ++++ GEI +   VD  +   + +  +GY ++   F + +C     ++ QS  I   V  
Sbjct: 57  LIMVGGEILTTGYVDVVQTGWKVLNRLGYTEND--FSFLSC-----INSQSSEINQAVQS 109

Query: 448 NRNDEEVGAGDQGLMFGYA 504
           N   +E+GAGDQG+  GYA
Sbjct: 110 N---DEIGAGDQGITVGYA 125


>UniRef50_Q1VNA9 Cluster: S-adenosylmethionine synthetase; n=1;
           Psychroflexus torquis ATCC 700755|Rep:
           S-adenosylmethionine synthetase - Psychroflexus torquis
           ATCC 700755
          Length = 344

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 31/84 (36%), Positives = 46/84 (54%), Gaps = 3/84 (3%)
 Frame = +1

Query: 265 GMVLLCGEITSKANV---DYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAA 435
           G+V++ GEI+  AN+   D + +V E +       S + F+    ++   L  QS  I A
Sbjct: 34  GLVMVGGEISEIANISTEDIKTIVHEALNKT-IKTSFEDFNLDRLNIYNELTPQSEEIRA 92

Query: 436 GVHENRNDEEVGAGDQGLMFGYAT 507
            V E   DE+ GAGDQG+M G+AT
Sbjct: 93  AVEE---DEDQGAGDQGIMIGFAT 113


>UniRef50_A6PKG8 Cluster: Methionine adenosyltransferase precursor;
           n=1; Victivallis vadensis ATCC BAA-548|Rep: Methionine
           adenosyltransferase precursor - Victivallis vadensis
           ATCC BAA-548
          Length = 338

 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 22/43 (51%), Positives = 29/43 (67%)
 Frame = +2

Query: 134 LFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKLK 262
           L TSE V  GHPDK+ D IS  +LD HL++DP  + A E ++K
Sbjct: 2   LKTSEWVSLGHPDKIADYISCYLLDRHLDRDPYTRFAVEVQIK 44



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 36/94 (38%), Positives = 43/94 (45%), Gaps = 10/94 (10%)
 Frame = +1

Query: 253 QTKTGMVLLCGEITSKANV---DYQKVVRETVKHIGYDDSSK---GFDYKTCS----VML 402
           Q K   V L GE+TSKAN    D    VR  V  IGY    +   G +   C     V  
Sbjct: 42  QIKDNHVTLGGEVTSKANYSPEDIAAFVRAAVNQIGYTPEYQKRWGKENTICGDDLIVTQ 101

Query: 403 ALDQQSPNIAAGVHENRNDEEVGAGDQGLMFGYA 504
            + QQSP+IA GV  +      G GDQG+  G A
Sbjct: 102 HIGQQSPDIAQGVDAD------GYGDQGIFHGMA 129


>UniRef50_Q6A7D8 Cluster: S-adenosylmethionine synthetase; n=11;
           Bacteria|Rep: S-adenosylmethionine synthetase -
           Propionibacterium acnes
          Length = 396

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 22/37 (59%), Positives = 26/37 (70%)
 Frame = +2

Query: 140 TSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 250
           T+ESV  GHPDK+ DQI+D ILD  L  D  A+VA E
Sbjct: 6   TAESVCAGHPDKLADQIADQILDDILYDDKAARVAVE 42


>UniRef50_Q95QX7 Cluster: Putative uncharacterized protein; n=1;
           Caenorhabditis elegans|Rep: Putative uncharacterized
           protein - Caenorhabditis elegans
          Length = 84

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 18/19 (94%), Positives = 18/19 (94%)
 Frame = +2

Query: 131 FLFTSESVGEGHPDKMCDQ 187
           FLFTSESV EGHPDKMCDQ
Sbjct: 6   FLFTSESVSEGHPDKMCDQ 24


>UniRef50_Q7R6Z1 Cluster: Putative uncharacterized protein PY07799;
            n=2; cellular organisms|Rep: Putative uncharacterized
            protein PY07799 - Plasmodium yoelii yoelii
          Length = 1022

 Score = 44.0 bits (99), Expect = 0.003
 Identities = 31/101 (30%), Positives = 45/101 (44%)
 Frame = -1

Query: 501  ITEHQALVSCPNFLVISVLMHPSSNVW*LLV*CEHHTACLVIKAFGRIIITNMFDRFAHN 322
            + EHQ LV+   F+V+   +H   +V  LL       A L I+A   +++ ++    AH 
Sbjct: 899  VAEHQTLVARSLFVVVE-FVHTHGDVGRLLADGGQDGAALPIEADFGVVVADLVHDLAHQ 957

Query: 321  FLIIHVSFGCDFATQKHHTGFSLVSHATFASGS*FRCASRI 199
            FL +H   G DFA +  H G     H     G    C  RI
Sbjct: 958  FLGVHPGGGGDFAGEHDHAGLHEGFHGHAGLG--ILCQDRI 996


>UniRef50_Q027Y1 Cluster: Methionine adenosyltransferase; n=1;
           Solibacter usitatus Ellin6076|Rep: Methionine
           adenosyltransferase - Solibacter usitatus (strain
           Ellin6076)
          Length = 364

 Score = 37.9 bits (84), Expect = 0.20
 Identities = 16/39 (41%), Positives = 25/39 (64%)
 Frame = +2

Query: 134 LFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 250
           L+ +E V  GHPDK+CD I+DA+++  +  +  A  A E
Sbjct: 2   LYAAEYVLPGHPDKLCDAIADALVEEAVRHEKRALCAIE 40


>UniRef50_A4DEX8 Cluster: Putative uncharacterized protein; n=1;
           Listeria monocytogenes FSL N1-017|Rep: Putative
           uncharacterized protein - Listeria monocytogenes FSL
           N1-017
          Length = 277

 Score = 37.9 bits (84), Expect = 0.20
 Identities = 19/64 (29%), Positives = 33/64 (51%)
 Frame = +2

Query: 146 ESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKLKPVWCFCVAKSHPKLTWIIKKL 325
           E V   HPDK+ D+IS AI+D    ++ + K+A E  +    C  + ++   L++   + 
Sbjct: 20  EKVNPSHPDKIADRISGAIVDLAYQEETNPKIAVEVLIGHGICHVIIETSAALSFEEVRK 79

Query: 326 CAKR 337
             KR
Sbjct: 80  AIKR 83


>UniRef50_UPI0000ECA413 Cluster: Endothelial cell-selective adhesion
           molecule precursor.; n=2; Gallus gallus|Rep: Endothelial
           cell-selective adhesion molecule precursor. - Gallus
           gallus
          Length = 395

 Score = 35.5 bits (78), Expect = 1.0
 Identities = 15/57 (26%), Positives = 28/57 (49%)
 Frame = +2

Query: 188 ISDAILDAHLNQDPDAKVACETKLKPVWCFCVAKSHPKLTWIIKKLCAKRSNILVMM 358
           +  A+L+ H+       V  E  + P W    ++  P ++W++KK  AK+  IL  +
Sbjct: 23  VCSAVLEVHVGTGSVYSVEGEGAVLPAWYTSSSQKRPYISWMLKKAAAKQFQILTYL 79


>UniRef50_Q8FXU7 Cluster: Protease, putative; n=6; Brucellaceae|Rep:
           Protease, putative - Brucella suis
          Length = 261

 Score = 35.1 bits (77), Expect = 1.4
 Identities = 11/37 (29%), Positives = 24/37 (64%)
 Frame = +2

Query: 107 YDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHL 217
           YD + G++  + SE++G+GH + + D +  A+ +A +
Sbjct: 50  YDSDSGAMLAYVSENIGKGHAEVLMDYVGQAMREAQI 86


>UniRef50_Q8ETA1 Cluster: Hypothetical conserved protein; n=1;
           Oceanobacillus iheyensis|Rep: Hypothetical conserved
           protein - Oceanobacillus iheyensis
          Length = 868

 Score = 35.1 bits (77), Expect = 1.4
 Identities = 22/101 (21%), Positives = 44/101 (43%), Gaps = 2/101 (1%)
 Frame = +2

Query: 56  MPETSKMNGYAKTNGHSYDMEDGSVFLFTSESVGEG--HPDKMCDQISDAILDAHLNQDP 229
           + ET   +GY K  G +  +E G  +  + E  GEG  +     ++  D + +   N + 
Sbjct: 133 LSETLLQSGYDKEIGDTITLEVGERYSLSDEMEGEGPLNQTVSAERTEDGLAEELRNTEE 192

Query: 230 DAKVACETKLKPVWCFCVAKSHPKLTWIIKKLCAKRSNILV 352
                  T  +P+W +  A  +  L++I + + +   N+ V
Sbjct: 193 HTFTIVGTIEEPLWDYSWAPGYSMLSYIDEDILSTEENVTV 233


>UniRef50_A6RT45 Cluster: Putative uncharacterized protein; n=2;
           Sclerotiniaceae|Rep: Putative uncharacterized protein -
           Botryotinia fuckeliana B05.10
          Length = 345

 Score = 34.3 bits (75), Expect = 2.4
 Identities = 14/34 (41%), Positives = 24/34 (70%)
 Frame = +1

Query: 124 ISIFVHIGICWRGSSRQNVRPNKRRYSRRASESG 225
           I+  +H+G+C  G+SR++V+  +R  SR+A  SG
Sbjct: 282 IAWVIHVGMCCCGASRRDVKSGRRMGSRKAYSSG 315


>UniRef50_UPI00006A2011 Cluster: Tumor necrosis factor receptor
           superfamily member 19L precursor (Receptor expressed in
           lymphoid tissues).; n=1; Xenopus tropicalis|Rep: Tumor
           necrosis factor receptor superfamily member 19L
           precursor (Receptor expressed in lymphoid tissues). -
           Xenopus tropicalis
          Length = 313

 Score = 33.9 bits (74), Expect = 3.2
 Identities = 16/40 (40%), Positives = 19/40 (47%)
 Frame = -3

Query: 478 LLPQLPRHFCSHAPQQQCLVIVGLVRASHCMSCNQSLWTN 359
           LLPQ+P H C H      +    L   S C  C+Q  WTN
Sbjct: 223 LLPQMP-HLCKHQHHLHTVQGPALPTGSCCSRCSQKKWTN 261


>UniRef50_Q15TP8 Cluster: Adenosine deaminase; n=2;
           Gammaproteobacteria|Rep: Adenosine deaminase -
           Pseudoalteromonas atlantica (strain T6c / BAA-1087)
          Length = 537

 Score = 33.9 bits (74), Expect = 3.2
 Identities = 15/52 (28%), Positives = 26/52 (50%)
 Frame = +1

Query: 307 VDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVHENRNDE 462
           VD  + +   +  +G +D+ KG+  +  S +  L Q+ PNI   +H    DE
Sbjct: 317 VDRHRDIYVGINMVGREDNDKGYPLRFLSTLRKLRQRIPNIPLAIHAGEVDE 368


>UniRef50_A4A0G4 Cluster: DNA-binding protein; n=1; Blastopirellula
           marina DSM 3645|Rep: DNA-binding protein -
           Blastopirellula marina DSM 3645
          Length = 687

 Score = 33.5 bits (73), Expect = 4.2
 Identities = 13/33 (39%), Positives = 24/33 (72%)
 Frame = +2

Query: 146 ESVGEGHPDKMCDQISDAILDAHLNQDPDAKVA 244
           ++V  GHP ++ + + DA+L+A + + PDAK+A
Sbjct: 311 KAVRLGHPARVSESLHDALLEALVREHPDAKLA 343


>UniRef50_A7SQA7 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 895

 Score = 33.5 bits (73), Expect = 4.2
 Identities = 16/46 (34%), Positives = 28/46 (60%), Gaps = 1/46 (2%)
 Frame = +3

Query: 9   RGTVWGYISGLTLNSECRRLQK*MDTRK-PTDTVMIWKMDQYFCSH 143
           RG VW  ++GL+ N E     K + T++ PT+ V++W + + F +H
Sbjct: 406 RGQVWQMMAGLSENDELVDSYKHLFTKESPTEQVIVWDIHRTFPAH 451


>UniRef50_Q4QGM3 Cluster: Putative uncharacterized protein; n=3;
           Leishmania|Rep: Putative uncharacterized protein -
           Leishmania major
          Length = 846

 Score = 33.1 bits (72), Expect = 5.6
 Identities = 17/46 (36%), Positives = 25/46 (54%)
 Frame = -3

Query: 556 SLCASTTVNGMHSSVSLLHNRTSSPGLLPQLPRHFCSHAPQQQCLV 419
           +LC S T N M   +S+ HN  S  G++ QL R  C H   ++ L+
Sbjct: 493 TLCRSLTTNAMLKVLSMRHNNLSPDGVV-QLGRSLCRHPCLERLLL 537


>UniRef50_UPI0000498BC3 Cluster: conserved hypothetical protein;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: conserved
           hypothetical protein - Entamoeba histolytica HM-1:IMSS
          Length = 592

 Score = 32.7 bits (71), Expect = 7.3
 Identities = 16/48 (33%), Positives = 24/48 (50%)
 Frame = +1

Query: 199 YSRRASESGSGRKSCM*NQTKTGMVLLCGEITSKANVDYQKVVRETVK 342
           + R   E G  + +C  NQTK G  ++CG   +       ++V ETVK
Sbjct: 413 HCRHVFEDGEEKVACYVNQTKDGNCVVCGCYYTHHKYSTYRIVYETVK 460


>UniRef50_Q1LVK4 Cluster: Novel fork head domain containing protein;
           n=3; Clupeocephala|Rep: Novel fork head domain
           containing protein - Danio rerio (Zebrafish)
           (Brachydanio rerio)
          Length = 379

 Score = 32.7 bits (71), Expect = 7.3
 Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
 Frame = -3

Query: 538 TVNGMHSSVSLLHNRTSSPGLLPQLPRHFCSHAPQQQCLVIVGLVRASHC-MSCNQ 374
           T+   HSS +  H+   +  +L Q  RHF S AP  + L+I     A++  M C Q
Sbjct: 226 TLQHRHSSPAAAHHSNYAASVLSQSARHFSSVAPAAERLLIPSSQEATYYGMGCEQ 281


>UniRef50_A7MES0 Cluster: Putative uncharacterized protein; n=1;
           Enterobacter sakazakii ATCC BAA-894|Rep: Putative
           uncharacterized protein - Enterobacter sakazakii ATCC
           BAA-894
          Length = 1383

 Score = 32.7 bits (71), Expect = 7.3
 Identities = 19/51 (37%), Positives = 25/51 (49%)
 Frame = +2

Query: 119 DGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKLKPVW 271
           D    LF+   V E  PD   D+ +D +L+ H   DP A  A  T + PVW
Sbjct: 294 DADDVLFSGHKVTE--PDAFYDE-NDPLLNGHSIADPAAVAAAATPVAPVW 341


>UniRef50_A0NE72 Cluster: ENSANGP00000030279; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000030279 - Anopheles gambiae
           str. PEST
          Length = 161

 Score = 32.7 bits (71), Expect = 7.3
 Identities = 18/57 (31%), Positives = 32/57 (56%), Gaps = 1/57 (1%)
 Frame = -1

Query: 390 ACLVIKAFGRIIITNMF-DRFAHNFLIIHVSFGCDFATQKHHTGFSLVSHATFASGS 223
           +C+++K+  R+I  N+  +  + N +++H +          H GF+ VS A FASGS
Sbjct: 86  SCVIVKSLPRLISLNLSRNSLSENSIVLH-NLPSLVTLVLSHNGFNQVSVALFASGS 141


>UniRef50_Q4SDE4 Cluster: Chromosome 3 SCAF14639, whole genome
           shotgun sequence; n=4; Tetraodontidae|Rep: Chromosome 3
           SCAF14639, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 825

 Score = 32.3 bits (70), Expect = 9.7
 Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
 Frame = +1

Query: 292 TSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNI-AAGVHENRNDEEV 468
           TS+ N+DYQ+VVR   +   +D   KGF   T  V   L+  + +I    +HE  N+ ++
Sbjct: 713 TSEINLDYQEVVRYKKRFHKFDKERKGF-ITTVDVQQVLENINVHIDENSLHEILNEVDL 771

Query: 469 GAGDQ 483
               Q
Sbjct: 772 NKNGQ 776


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 682,371,178
Number of Sequences: 1657284
Number of extensions: 14505679
Number of successful extensions: 37981
Number of sequences better than 10.0: 51
Number of HSP's better than 10.0 without gapping: 36536
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 37942
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 45636850930
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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