Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= NV060991.seq
(689 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC039600-1|AAH39600.1| 1049|Homo sapiens hect domain and RLD 4 p... 106 9e-23
AY650033-1|AAV66579.1| 979|Homo sapiens HECT and RCC1 containin... 106 9e-23
AY221963-1|AAO65480.1| 1057|Homo sapiens HECT and RCC1 containin... 106 9e-23
AL356741-3|CAH74148.1| 1049|Homo sapiens hect domain and RLD 4 p... 106 9e-23
AL133551-3|CAI16032.1| 1049|Homo sapiens hect domain and RLD 4 p... 106 9e-23
D25215-1|BAA04945.2| 1054|Homo sapiens KIAA0032 protein. 105 1e-22
BC038960-1|AAH38960.1| 368|Homo sapiens HERC3 protein protein. 105 1e-22
AC098582-1|AAY41038.1| 382|Homo sapiens unknown protein. 105 1e-22
BC042047-1|AAH42047.2| 1022|Homo sapiens hect domain and RLD 6 p... 103 8e-22
AY653203-1|AAV66897.1| 322|Homo sapiens truncated HERC6 protein. 103 8e-22
AY653202-1|AAV66896.1| 364|Homo sapiens truncated HERC6 protein. 103 8e-22
AY653201-1|AAV66895.1| 986|Homo sapiens HERC6 splice variant pr... 103 8e-22
AF336798-1|AAQ14893.1| 1022|Homo sapiens HERC6 protein. 103 8e-22
AB046813-1|BAB13419.1| 953|Homo sapiens KIAA1593 protein protein. 89 2e-17
U50078-1|AAD12586.1| 4861|Homo sapiens p532 protein. 87 7e-17
AB027289-1|BAA88519.1| 1024|Homo sapiens cyclin-E binding protei... 84 4e-16
AY337518-1|AAR00320.1| 1024|Homo sapiens HECT E3 ubiquitin ligas... 84 5e-16
AF071172-1|AAD08657.1| 4834|Homo sapiens HERC2 protein. 83 1e-15
BC038104-1|AAH38104.1| 355|Homo sapiens RCBTB1 protein protein. 80 6e-15
AL139321-5|CAH71047.1| 531|Homo sapiens regulator of chromosome... 80 6e-15
AK096654-1|BAC04833.1| 531|Homo sapiens protein ( Homo sapiens ... 80 6e-15
AJ319660-1|CAC40027.1| 531|Homo sapiens guanine nucleotide exch... 80 6e-15
AF334406-1|AAK38372.1| 531|Homo sapiens CLLL7 protein protein. 80 6e-15
AK092403-1|BAC03879.1| 184|Homo sapiens protein ( Homo sapiens ... 80 8e-15
BC029052-1|AAH29052.1| 551|Homo sapiens regulator of chromosome... 79 2e-14
AY341245-1|AAP88928.1| 551|Homo sapiens chromosome condensation... 79 2e-14
AL157813-1|CAH70795.1| 551|Homo sapiens regulator of chromosome... 79 2e-14
AF224249-1|AAO27475.1| 328|Homo sapiens HERC2 protein. 79 2e-14
AF060219-1|AAC79987.1| 551|Homo sapiens RCC1-like G exchanging ... 79 2e-14
AB209543-1|BAD92780.1| 556|Homo sapiens RCC1-like G exchanging ... 79 2e-14
AC004460-2|AAC06339.1| 371|Homo sapiens WUGSC:H_DJ1086D14.2 pro... 78 3e-14
AF225407-1|AAO27483.1| 409|Homo sapiens HERC2 protein. 77 6e-14
AL356741-1|CAH74146.1| 907|Homo sapiens hect domain and RLD 4 p... 74 6e-13
AL133551-1|CAI16031.1| 907|Homo sapiens hect domain and RLD 4 p... 74 6e-13
BC142946-1|AAI42947.1| 457|Homo sapiens RCC2 protein protein. 69 2e-11
BC053908-1|AAH53908.1| 522|Homo sapiens RCC2 protein protein. 69 2e-11
BC042141-1|AAH42141.1| 522|Homo sapiens regulator of chromosome... 69 2e-11
AL359612-1|CAB94882.1| 333|Homo sapiens hypothetical protein pr... 69 2e-11
AJ421269-1|CAD13148.1| 522|Homo sapiens RCC1-like protein protein. 69 2e-11
AB040903-1|BAA95994.1| 564|Homo sapiens KIAA1470 protein protein. 69 2e-11
BC071576-1|AAH71576.1| 1237|Homo sapiens ALS2 protein protein. 65 2e-10
BC040929-1|AAH40929.1| 651|Homo sapiens HERC1 protein protein. 65 3e-10
X97668-1|CAA66258.1| 815|Homo sapiens XLRP3 protein. 63 8e-10
U57629-1|AAC50481.1| 815|Homo sapiens retinitis pigmentosa GTPa... 63 8e-10
BC031624-1|AAH31624.1| 480|Homo sapiens RPGR protein protein. 63 8e-10
BC029174-1|AAH29174.1| 812|Homo sapiens ALS2 protein protein. 63 8e-10
AL606748-2|CAI95407.1| 815|Homo sapiens retinitis pigmentosa GT... 63 8e-10
AK223491-1|BAD97211.1| 815|Homo sapiens retinitis pigmentosa GT... 63 8e-10
AJ238395-1|CAB54002.1| 646|Homo sapiens RPGR protein protein. 63 8e-10
AF391100-1|AAL14103.1| 1657|Homo sapiens alsin protein. 63 8e-10
AC007279-1|AAY15058.1| 1598|Homo sapiens unknown protein. 63 8e-10
AB053305-1|BAB69014.1| 1657|Homo sapiens ALS2 protein. 63 8e-10
AB046783-1|BAB13389.2| 1658|Homo sapiens KIAA1563 protein protein. 63 8e-10
BC112101-1|AAI12102.1| 979|Homo sapiens NIMA related kinase 9 p... 63 1e-09
BC093881-1|AAH93881.1| 979|Homo sapiens NIMA (never in mitosis ... 63 1e-09
AY080896-1|AAL87410.1| 979|Homo sapiens NIMA-family kinase NERC... 63 1e-09
AY048580-1|AAL05428.1| 979|Homo sapiens NIMA-related kinase Nek... 63 1e-09
AJ318463-1|CAC86116.1| 815|Homo sapiens retinitis pigmentosa GT... 63 1e-09
AC007055-4|AAD31939.1| 414|Homo sapiens protein ( Homo sapiens ... 63 1e-09
AB082526-1|BAC02704.1| 1011|Homo sapiens KIAA1995 protein protein. 63 1e-09
BC004933-1|AAH04933.1| 351|Homo sapiens RCC2 protein protein. 61 3e-09
BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis ... 60 1e-08
BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8 p... 60 1e-08
AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8... 60 1e-08
AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a... 60 1e-08
AK023024-1|BAB14362.1| 396|Homo sapiens protein ( Homo sapiens ... 59 2e-08
AB053306-1|BAB69015.1| 396|Homo sapiens ALS2 protein. 59 2e-08
BC065375-1|AAH65375.1| 458|Homo sapiens secretion regulating gu... 58 4e-08
AJ243951-1|CAB60833.1| 288|Homo sapiens deafness locus associat... 58 4e-08
AJ243950-1|CAB60832.1| 458|Homo sapiens deafness locus associat... 58 4e-08
X12654-1|CAA31182.1| 421|Homo sapiens protein ( Human mRNA for ... 55 2e-07
X06130-1|CAA29496.1| 421|Homo sapiens protein ( Human mRNA for ... 55 2e-07
D00591-1|BAA00469.1| 421|Homo sapiens RCC1 protein. 55 2e-07
CR407693-1|CAG28621.1| 421|Homo sapiens CHC1 protein. 55 2e-07
BC069198-1|AAH69198.1| 452|Homo sapiens regulator of chromosome... 55 2e-07
BC036903-1|AAH36903.1| 421|Homo sapiens regulator of chromosome... 55 2e-07
BC010067-1|AAH10067.1| 421|Homo sapiens regulator of chromosome... 55 2e-07
BC007300-1|AAH07300.1| 421|Homo sapiens regulator of chromosome... 55 2e-07
AL513497-2|CAI22287.1| 421|Homo sapiens regulator of chromosome... 55 2e-07
AF498924-1|AAM21072.1| 421|Homo sapiens regulator of chromosome... 55 2e-07
BC040695-1|AAH40695.1| 358|Homo sapiens WBSCR16 protein protein. 54 5e-07
BC032712-1|AAH32712.1| 454|Homo sapiens WBSCR16 protein protein. 54 5e-07
BC019008-1|AAH19008.1| 464|Homo sapiens Williams-Beuren syndrom... 54 5e-07
BC007823-1|AAH07823.1| 464|Homo sapiens Williams-Beuren syndrom... 54 5e-07
AF410455-1|AAM62304.1| 464|Homo sapiens RCC1-like G exchanging ... 54 5e-07
AL359257-2|CAI39759.1| 4640|Homo sapiens AC001226.5 protein. 53 8e-07
AL159158-1|CAI16842.1| 4640|Homo sapiens AC001226.5 protein. 53 8e-07
AL159154-1|CAH73736.1| 4640|Homo sapiens AC001226.5 protein. 53 8e-07
AF075587-1|AAC39928.1| 4641|Homo sapiens protein associated with... 53 8e-07
BC113826-1|AAI13827.1| 244|Homo sapiens RCCD1 protein protein. 48 2e-05
DQ005634-1|AAY55907.1| 1196|Homo sapiens inhibitor of Bruton's t... 47 6e-05
DQ005633-1|AAY55906.1| 1353|Homo sapiens inhibitor of Bruton's t... 47 6e-05
BC113698-1|AAI13699.1| 1353|Homo sapiens inhibitor of Bruton aga... 47 6e-05
BC113696-1|AAI13697.1| 1353|Homo sapiens inhibitor of Bruton aga... 47 6e-05
AL050333-2|CAI23416.1| 1187|Homo sapiens RP1-93K22.1 protein. 47 6e-05
AB037838-1|BAA92655.2| 1379|Homo sapiens KIAA1417 protein protein. 47 6e-05
AY650034-1|AAV66580.1| 110|Homo sapiens HECT and RCC1 containin... 44 7e-04
AY650032-1|AAV66578.1| 117|Homo sapiens HECT and RCC1 containin... 44 7e-04
AF225404-1|AAO27482.1| 259|Homo sapiens HERC2 protein. 39 0.019
BC067293-1|AAH67293.1| 580|Homo sapiens F-box protein 24 protein. 34 0.55
AC069281-1|AAP21863.1| 580|Homo sapiens unknown protein. 34 0.55
>BC039600-1|AAH39600.1| 1049|Homo sapiens hect domain and RLD 4
protein.
Length = 1049
Score = 106 bits (254), Expect = 9e-23
Identities = 49/127 (38%), Positives = 76/127 (59%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
++CG H+LA+++ GQ ++WG DS GQLG P+ +K L+ ++QVACG YH
Sbjct: 89 VSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACGYYH 148
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
S+AL+ + +++ WG N YGQ GL ++ Q + SL+G+P + G H+FVL+ S
Sbjct: 149 SLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLS 208
Query: 620 RCGFWMG 640
F G
Sbjct: 209 GAIFGWG 215
Score = 88.6 bits (210), Expect = 2e-17
Identities = 48/127 (37%), Positives = 62/127 (48%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG HSLA+ + + F WG + GQLG Q P+ +K L +QVA G H
Sbjct: 142 VACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAH 201
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
S LT SG ++ WG N +GQ GL R + SL I I CG +HT L+K
Sbjct: 202 SFVLTLSGAIFGWGRNKFGQLGLNDENDRYVP-NLLKSLRSQKIVYICCGEDHTAALTKE 260
Query: 620 RCGFWMG 640
F G
Sbjct: 261 GGVFTFG 267
Score = 82.2 bits (194), Expect = 2e-15
Identities = 42/127 (33%), Positives = 73/127 (57%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ CGL+H++ + + G ++ G + +GQLG+ ++ KP+ V L +N++ V+CG H
Sbjct: 39 VGCGLRHTVFVLDDGTVYTCGCNDLGQLGHE---KSRKKPEQVVALDAQNIVAVSCGEAH 95
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
++AL + G +Y+WG +S GQ GL + ++I SL + I + CG H+ LSK+
Sbjct: 96 TLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKA 155
Query: 620 RCGFWMG 640
F G
Sbjct: 156 SEVFCWG 162
Score = 73.7 bits (173), Expect = 6e-13
Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 2/123 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+A G HS + G F WG + GQLG N + + P +K L ++ ++ + CG H
Sbjct: 195 VAAGGAHSFVLTLSGAIFGWGRNKFGQLGLN-DENDRYVPNLLKSLRSQKIVYICCGEDH 253
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHT--FVLS 613
+ ALT G ++++GA YGQ G + + + + + L+G + I CG HT FV S
Sbjct: 254 TAALTKEGGVFTFGAGGYGQLG-HNSTSHEINPRKVFELMGSIVTEIACGRQHTSAFVPS 312
Query: 614 KSR 622
R
Sbjct: 313 SGR 315
Score = 52.8 bits (121), Expect = 1e-06
Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 317 WGSDSMGQLG-NNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSY 493
WG+ S GQLG + +P+ K V V CG H+V + + G +Y+ G N
Sbjct: 4 WGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGCNDL 63
Query: 494 GQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
GQ G E ++RK + + +L I ++CG HT L+
Sbjct: 64 GQLGHE--KSRK-KPEQVVALDAQNIVAVSCGEAHTLALN 100
Score = 41.5 bits (93), Expect = 0.003
Identities = 16/50 (32%), Positives = 33/50 (66%)
Frame = +3
Query: 45 DLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQ 194
++V++P S + + ++ V G H++++ + G +Y+CG ND+GQLG +
Sbjct: 20 EIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGCNDLGQLGHE 69
Score = 38.3 bits (85), Expect = 0.026
Identities = 24/76 (31%), Positives = 38/76 (50%)
Frame = +3
Query: 9 DHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG 188
D +L + GS+ + + P K I VA G +HSL LS + ++ G N GQLG
Sbjct: 113 DGQLGLVGSE--ECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLG 170
Query: 189 RQTESDNGKNPALVET 236
T+ +P L+++
Sbjct: 171 LGTDCKKQTSPQLLKS 186
Score = 37.1 bits (82), Expect = 0.059
Identities = 19/60 (31%), Positives = 34/60 (56%)
Frame = +3
Query: 81 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIRQ 260
++ +I AV+ GE H+L L++ G +Y+ G + GQLG + + P +++ D I Q
Sbjct: 82 DAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQ 141
Score = 35.5 bits (78), Expect = 0.18
Identities = 17/35 (48%), Positives = 21/35 (60%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESD 206
VAAG HS L+ SG ++ G N GQLG E+D
Sbjct: 195 VAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDEND 229
Score = 31.1 bits (67), Expect = 3.9
Identities = 19/48 (39%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Frame = +2
Query: 254 TTIACGLQHSLA-IDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG 394
T IACG QH+ A + G+ +S+G GQLG ++ + P VKG
Sbjct: 297 TEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSN-RKSPFTVKG 343
Score = 30.3 bits (65), Expect = 6.8
Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Frame = +3
Query: 93 IQAVAAGEFH-SLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 233
+ +A G H S ++ +SG +YS G GQLG + S N K+P V+
Sbjct: 296 VTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTS-NRKSPFTVK 342
>AY650033-1|AAV66579.1| 979|Homo sapiens HECT and RCC1 containing
protein 4 isoform 3 protein.
Length = 979
Score = 106 bits (254), Expect = 9e-23
Identities = 49/127 (38%), Positives = 76/127 (59%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
++CG H+LA+++ GQ ++WG DS GQLG P+ +K L+ ++QVACG YH
Sbjct: 89 VSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACGYYH 148
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
S+AL+ + +++ WG N YGQ GL ++ Q + SL+G+P + G H+FVL+ S
Sbjct: 149 SLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLS 208
Query: 620 RCGFWMG 640
F G
Sbjct: 209 GAIFGWG 215
Score = 88.6 bits (210), Expect = 2e-17
Identities = 48/127 (37%), Positives = 62/127 (48%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG HSLA+ + + F WG + GQLG Q P+ +K L +QVA G H
Sbjct: 142 VACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAH 201
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
S LT SG ++ WG N +GQ GL R + SL I I CG +HT L+K
Sbjct: 202 SFVLTLSGAIFGWGRNKFGQLGLNDENDRYVP-NLLKSLRSQKIVYICCGEDHTAALTKE 260
Query: 620 RCGFWMG 640
F G
Sbjct: 261 GGVFTFG 267
Score = 82.2 bits (194), Expect = 2e-15
Identities = 42/127 (33%), Positives = 73/127 (57%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ CGL+H++ + + G ++ G + +GQLG+ ++ KP+ V L +N++ V+CG H
Sbjct: 39 VGCGLRHTVFVLDDGTVYTCGCNDLGQLGHE---KSRKKPEQVVALDAQNIVAVSCGEAH 95
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
++AL + G +Y+WG +S GQ GL + ++I SL + I + CG H+ LSK+
Sbjct: 96 TLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKA 155
Query: 620 RCGFWMG 640
F G
Sbjct: 156 SEVFCWG 162
Score = 73.7 bits (173), Expect = 6e-13
Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 2/123 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+A G HS + G F WG + GQLG N + + P +K L ++ ++ + CG H
Sbjct: 195 VAAGGAHSFVLTLSGAIFGWGRNKFGQLGLN-DENDRYVPNLLKSLRSQKIVYICCGEDH 253
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHT--FVLS 613
+ ALT G ++++GA YGQ G + + + + + L+G + I CG HT FV S
Sbjct: 254 TAALTKEGGVFTFGAGGYGQLG-HNSTSHEINPRKVFELMGSIVTEIACGRQHTSAFVPS 312
Query: 614 KSR 622
R
Sbjct: 313 SGR 315
Score = 52.8 bits (121), Expect = 1e-06
Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 317 WGSDSMGQLG-NNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSY 493
WG+ S GQLG + +P+ K V V CG H+V + + G +Y+ G N
Sbjct: 4 WGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGCNDL 63
Query: 494 GQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
GQ G E ++RK + + +L I ++CG HT L+
Sbjct: 64 GQLGHE--KSRK-KPEQVVALDAQNIVAVSCGEAHTLALN 100
Score = 41.5 bits (93), Expect = 0.003
Identities = 16/50 (32%), Positives = 33/50 (66%)
Frame = +3
Query: 45 DLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQ 194
++V++P S + + ++ V G H++++ + G +Y+CG ND+GQLG +
Sbjct: 20 EIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGCNDLGQLGHE 69
Score = 38.3 bits (85), Expect = 0.026
Identities = 24/76 (31%), Positives = 38/76 (50%)
Frame = +3
Query: 9 DHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG 188
D +L + GS+ + + P K I VA G +HSL LS + ++ G N GQLG
Sbjct: 113 DGQLGLVGSE--ECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLG 170
Query: 189 RQTESDNGKNPALVET 236
T+ +P L+++
Sbjct: 171 LGTDCKKQTSPQLLKS 186
Score = 37.1 bits (82), Expect = 0.059
Identities = 19/60 (31%), Positives = 34/60 (56%)
Frame = +3
Query: 81 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIRQ 260
++ +I AV+ GE H+L L++ G +Y+ G + GQLG + + P +++ D I Q
Sbjct: 82 DAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQ 141
Score = 35.5 bits (78), Expect = 0.18
Identities = 17/35 (48%), Positives = 21/35 (60%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESD 206
VAAG HS L+ SG ++ G N GQLG E+D
Sbjct: 195 VAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDEND 229
Score = 31.1 bits (67), Expect = 3.9
Identities = 19/48 (39%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Frame = +2
Query: 254 TTIACGLQHSLA-IDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG 394
T IACG QH+ A + G+ +S+G GQLG ++ + P VKG
Sbjct: 297 TEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSN-RKSPFTVKG 343
Score = 30.3 bits (65), Expect = 6.8
Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Frame = +3
Query: 93 IQAVAAGEFH-SLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 233
+ +A G H S ++ +SG +YS G GQLG + S N K+P V+
Sbjct: 296 VTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTS-NRKSPFTVK 342
>AY221963-1|AAO65480.1| 1057|Homo sapiens HECT and RCC1 containing
protein 4 isoform 1 protein.
Length = 1057
Score = 106 bits (254), Expect = 9e-23
Identities = 49/127 (38%), Positives = 76/127 (59%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
++CG H+LA+++ GQ ++WG DS GQLG P+ +K L+ ++QVACG YH
Sbjct: 89 VSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACGYYH 148
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
S+AL+ + +++ WG N YGQ GL ++ Q + SL+G+P + G H+FVL+ S
Sbjct: 149 SLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLS 208
Query: 620 RCGFWMG 640
F G
Sbjct: 209 GAIFGWG 215
Score = 88.6 bits (210), Expect = 2e-17
Identities = 48/127 (37%), Positives = 62/127 (48%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG HSLA+ + + F WG + GQLG Q P+ +K L +QVA G H
Sbjct: 142 VACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAH 201
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
S LT SG ++ WG N +GQ GL R + SL I I CG +HT L+K
Sbjct: 202 SFVLTLSGAIFGWGRNKFGQLGLNDENDRYVP-NLLKSLRSQKIVYICCGEDHTAALTKE 260
Query: 620 RCGFWMG 640
F G
Sbjct: 261 GGVFTFG 267
Score = 82.2 bits (194), Expect = 2e-15
Identities = 42/127 (33%), Positives = 73/127 (57%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ CGL+H++ + + G ++ G + +GQLG+ ++ KP+ V L +N++ V+CG H
Sbjct: 39 VGCGLRHTVFVLDDGTVYTCGCNDLGQLGHE---KSRKKPEQVVALDAQNIVAVSCGEAH 95
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
++AL + G +Y+WG +S GQ GL + ++I SL + I + CG H+ LSK+
Sbjct: 96 TLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKA 155
Query: 620 RCGFWMG 640
F G
Sbjct: 156 SEVFCWG 162
Score = 73.7 bits (173), Expect = 6e-13
Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 2/123 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+A G HS + G F WG + GQLG N + + P +K L ++ ++ + CG H
Sbjct: 195 VAAGGAHSFVLTLSGAIFGWGRNKFGQLGLN-DENDRYVPNLLKSLRSQKIVYICCGEDH 253
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHT--FVLS 613
+ ALT G ++++GA YGQ G + + + + + L+G + I CG HT FV S
Sbjct: 254 TAALTKEGGVFTFGAGGYGQLG-HNSTSHEINPRKVFELMGSIVTEIACGRQHTSAFVPS 312
Query: 614 KSR 622
R
Sbjct: 313 SGR 315
Score = 52.8 bits (121), Expect = 1e-06
Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 317 WGSDSMGQLG-NNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSY 493
WG+ S GQLG + +P+ K V V CG H+V + + G +Y+ G N
Sbjct: 4 WGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGCNDL 63
Query: 494 GQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
GQ G E ++RK + + +L I ++CG HT L+
Sbjct: 64 GQLGHE--KSRK-KPEQVVALDAQNIVAVSCGEAHTLALN 100
Score = 41.5 bits (93), Expect = 0.003
Identities = 16/50 (32%), Positives = 33/50 (66%)
Frame = +3
Query: 45 DLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQ 194
++V++P S + + ++ V G H++++ + G +Y+CG ND+GQLG +
Sbjct: 20 EIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGCNDLGQLGHE 69
Score = 38.3 bits (85), Expect = 0.026
Identities = 24/76 (31%), Positives = 38/76 (50%)
Frame = +3
Query: 9 DHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG 188
D +L + GS+ + + P K I VA G +HSL LS + ++ G N GQLG
Sbjct: 113 DGQLGLVGSE--ECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLG 170
Query: 189 RQTESDNGKNPALVET 236
T+ +P L+++
Sbjct: 171 LGTDCKKQTSPQLLKS 186
Score = 37.1 bits (82), Expect = 0.059
Identities = 19/60 (31%), Positives = 34/60 (56%)
Frame = +3
Query: 81 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIRQ 260
++ +I AV+ GE H+L L++ G +Y+ G + GQLG + + P +++ D I Q
Sbjct: 82 DAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQ 141
Score = 35.5 bits (78), Expect = 0.18
Identities = 17/35 (48%), Positives = 21/35 (60%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESD 206
VAAG HS L+ SG ++ G N GQLG E+D
Sbjct: 195 VAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDEND 229
Score = 31.1 bits (67), Expect = 3.9
Identities = 19/48 (39%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Frame = +2
Query: 254 TTIACGLQHSLA-IDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG 394
T IACG QH+ A + G+ +S+G GQLG ++ + P VKG
Sbjct: 297 TEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSN-RKSPFTVKG 343
Score = 30.3 bits (65), Expect = 6.8
Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Frame = +3
Query: 93 IQAVAAGEFH-SLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 233
+ +A G H S ++ +SG +YS G GQLG + S N K+P V+
Sbjct: 296 VTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTS-NRKSPFTVK 342
>AL356741-3|CAH74148.1| 1049|Homo sapiens hect domain and RLD 4
protein.
Length = 1049
Score = 106 bits (254), Expect = 9e-23
Identities = 49/127 (38%), Positives = 76/127 (59%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
++CG H+LA+++ GQ ++WG DS GQLG P+ +K L+ ++QVACG YH
Sbjct: 89 VSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACGYYH 148
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
S+AL+ + +++ WG N YGQ GL ++ Q + SL+G+P + G H+FVL+ S
Sbjct: 149 SLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLS 208
Query: 620 RCGFWMG 640
F G
Sbjct: 209 GAIFGWG 215
Score = 88.6 bits (210), Expect = 2e-17
Identities = 48/127 (37%), Positives = 62/127 (48%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG HSLA+ + + F WG + GQLG Q P+ +K L +QVA G H
Sbjct: 142 VACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAH 201
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
S LT SG ++ WG N +GQ GL R + SL I I CG +HT L+K
Sbjct: 202 SFVLTLSGAIFGWGRNKFGQLGLNDENDRYVP-NLLKSLRSQKIVYICCGEDHTAALTKE 260
Query: 620 RCGFWMG 640
F G
Sbjct: 261 GGVFTFG 267
Score = 82.2 bits (194), Expect = 2e-15
Identities = 42/127 (33%), Positives = 73/127 (57%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ CGL+H++ + + G ++ G + +GQLG+ ++ KP+ V L +N++ V+CG H
Sbjct: 39 VGCGLRHTVFVLDDGTVYTCGCNDLGQLGHE---KSRKKPEQVVALDAQNIVAVSCGEAH 95
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
++AL + G +Y+WG +S GQ GL + ++I SL + I + CG H+ LSK+
Sbjct: 96 TLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKA 155
Query: 620 RCGFWMG 640
F G
Sbjct: 156 SEVFCWG 162
Score = 73.7 bits (173), Expect = 6e-13
Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 2/123 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+A G HS + G F WG + GQLG N + + P +K L ++ ++ + CG H
Sbjct: 195 VAAGGAHSFVLTLSGAIFGWGRNKFGQLGLN-DENDRYVPNLLKSLRSQKIVYICCGEDH 253
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHT--FVLS 613
+ ALT G ++++GA YGQ G + + + + + L+G + I CG HT FV S
Sbjct: 254 TAALTKEGGVFTFGAGGYGQLG-HNSTSHEINPRKVFELMGSIVTEIACGRQHTSAFVPS 312
Query: 614 KSR 622
R
Sbjct: 313 SGR 315
Score = 52.8 bits (121), Expect = 1e-06
Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 317 WGSDSMGQLG-NNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSY 493
WG+ S GQLG + +P+ K V V CG H+V + + G +Y+ G N
Sbjct: 4 WGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGCNDL 63
Query: 494 GQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
GQ G E ++RK + + +L I ++CG HT L+
Sbjct: 64 GQLGHE--KSRK-KPEQVVALDAQNIVAVSCGEAHTLALN 100
Score = 41.5 bits (93), Expect = 0.003
Identities = 16/50 (32%), Positives = 33/50 (66%)
Frame = +3
Query: 45 DLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQ 194
++V++P S + + ++ V G H++++ + G +Y+CG ND+GQLG +
Sbjct: 20 EIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGCNDLGQLGHE 69
Score = 38.3 bits (85), Expect = 0.026
Identities = 24/76 (31%), Positives = 38/76 (50%)
Frame = +3
Query: 9 DHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG 188
D +L + GS+ + + P K I VA G +HSL LS + ++ G N GQLG
Sbjct: 113 DGQLGLVGSE--ECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLG 170
Query: 189 RQTESDNGKNPALVET 236
T+ +P L+++
Sbjct: 171 LGTDCKKQTSPQLLKS 186
Score = 37.1 bits (82), Expect = 0.059
Identities = 19/60 (31%), Positives = 34/60 (56%)
Frame = +3
Query: 81 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIRQ 260
++ +I AV+ GE H+L L++ G +Y+ G + GQLG + + P +++ D I Q
Sbjct: 82 DAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQ 141
Score = 35.5 bits (78), Expect = 0.18
Identities = 17/35 (48%), Positives = 21/35 (60%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESD 206
VAAG HS L+ SG ++ G N GQLG E+D
Sbjct: 195 VAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDEND 229
Score = 31.1 bits (67), Expect = 3.9
Identities = 19/48 (39%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Frame = +2
Query: 254 TTIACGLQHSLA-IDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG 394
T IACG QH+ A + G+ +S+G GQLG ++ + P VKG
Sbjct: 297 TEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSN-RKSPFTVKG 343
Score = 30.3 bits (65), Expect = 6.8
Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Frame = +3
Query: 93 IQAVAAGEFH-SLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 233
+ +A G H S ++ +SG +YS G GQLG + S N K+P V+
Sbjct: 296 VTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTS-NRKSPFTVK 342
>AL133551-3|CAI16032.1| 1049|Homo sapiens hect domain and RLD 4
protein.
Length = 1049
Score = 106 bits (254), Expect = 9e-23
Identities = 49/127 (38%), Positives = 76/127 (59%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
++CG H+LA+++ GQ ++WG DS GQLG P+ +K L+ ++QVACG YH
Sbjct: 89 VSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACGYYH 148
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
S+AL+ + +++ WG N YGQ GL ++ Q + SL+G+P + G H+FVL+ S
Sbjct: 149 SLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLS 208
Query: 620 RCGFWMG 640
F G
Sbjct: 209 GAIFGWG 215
Score = 88.6 bits (210), Expect = 2e-17
Identities = 48/127 (37%), Positives = 62/127 (48%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG HSLA+ + + F WG + GQLG Q P+ +K L +QVA G H
Sbjct: 142 VACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAH 201
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
S LT SG ++ WG N +GQ GL R + SL I I CG +HT L+K
Sbjct: 202 SFVLTLSGAIFGWGRNKFGQLGLNDENDRYVP-NLLKSLRSQKIVYICCGEDHTAALTKE 260
Query: 620 RCGFWMG 640
F G
Sbjct: 261 GGVFTFG 267
Score = 82.2 bits (194), Expect = 2e-15
Identities = 42/127 (33%), Positives = 73/127 (57%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ CGL+H++ + + G ++ G + +GQLG+ ++ KP+ V L +N++ V+CG H
Sbjct: 39 VGCGLRHTVFVLDDGTVYTCGCNDLGQLGHE---KSRKKPEQVVALDAQNIVAVSCGEAH 95
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
++AL + G +Y+WG +S GQ GL + ++I SL + I + CG H+ LSK+
Sbjct: 96 TLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKA 155
Query: 620 RCGFWMG 640
F G
Sbjct: 156 SEVFCWG 162
Score = 73.7 bits (173), Expect = 6e-13
Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 2/123 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+A G HS + G F WG + GQLG N + + P +K L ++ ++ + CG H
Sbjct: 195 VAAGGAHSFVLTLSGAIFGWGRNKFGQLGLN-DENDRYVPNLLKSLRSQKIVYICCGEDH 253
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHT--FVLS 613
+ ALT G ++++GA YGQ G + + + + + L+G + I CG HT FV S
Sbjct: 254 TAALTKEGGVFTFGAGGYGQLG-HNSTSHEINPRKVFELMGSIVTEIACGRQHTSAFVPS 312
Query: 614 KSR 622
R
Sbjct: 313 SGR 315
Score = 52.8 bits (121), Expect = 1e-06
Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 317 WGSDSMGQLG-NNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSY 493
WG+ S GQLG + +P+ K V V CG H+V + + G +Y+ G N
Sbjct: 4 WGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGCNDL 63
Query: 494 GQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
GQ G E ++RK + + +L I ++CG HT L+
Sbjct: 64 GQLGHE--KSRK-KPEQVVALDAQNIVAVSCGEAHTLALN 100
Score = 41.5 bits (93), Expect = 0.003
Identities = 16/50 (32%), Positives = 33/50 (66%)
Frame = +3
Query: 45 DLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQ 194
++V++P S + + ++ V G H++++ + G +Y+CG ND+GQLG +
Sbjct: 20 EIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGCNDLGQLGHE 69
Score = 38.3 bits (85), Expect = 0.026
Identities = 24/76 (31%), Positives = 38/76 (50%)
Frame = +3
Query: 9 DHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG 188
D +L + GS+ + + P K I VA G +HSL LS + ++ G N GQLG
Sbjct: 113 DGQLGLVGSE--ECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLG 170
Query: 189 RQTESDNGKNPALVET 236
T+ +P L+++
Sbjct: 171 LGTDCKKQTSPQLLKS 186
Score = 37.1 bits (82), Expect = 0.059
Identities = 19/60 (31%), Positives = 34/60 (56%)
Frame = +3
Query: 81 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIRQ 260
++ +I AV+ GE H+L L++ G +Y+ G + GQLG + + P +++ D I Q
Sbjct: 82 DAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQ 141
Score = 35.5 bits (78), Expect = 0.18
Identities = 17/35 (48%), Positives = 21/35 (60%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESD 206
VAAG HS L+ SG ++ G N GQLG E+D
Sbjct: 195 VAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDEND 229
Score = 31.1 bits (67), Expect = 3.9
Identities = 19/48 (39%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Frame = +2
Query: 254 TTIACGLQHSLA-IDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG 394
T IACG QH+ A + G+ +S+G GQLG ++ + P VKG
Sbjct: 297 TEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSN-RKSPFTVKG 343
Score = 30.3 bits (65), Expect = 6.8
Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Frame = +3
Query: 93 IQAVAAGEFH-SLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 233
+ +A G H S ++ +SG +YS G GQLG + S N K+P V+
Sbjct: 296 VTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTS-NRKSPFTVK 342
>D25215-1|BAA04945.2| 1054|Homo sapiens KIAA0032 protein.
Length = 1054
Score = 105 bits (253), Expect = 1e-22
Identities = 51/131 (38%), Positives = 74/131 (56%)
Frame = +2
Query: 248 HNTTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 427
H +ACG HSLA+ + GQ FSWG+ S GQLG + P+ ++ L + ++QV+C
Sbjct: 89 HIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSC 148
Query: 428 GAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFV 607
G +H +AL G ++WG NS+GQ GL + Q + SL G+P+A + G H+F
Sbjct: 149 GNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFA 208
Query: 608 LSKSRCGFWMG 640
LS S F G
Sbjct: 209 LSLSGAVFGWG 219
Score = 88.2 bits (209), Expect = 2e-17
Identities = 50/127 (39%), Positives = 69/127 (54%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
++CG H LA+ GQ F+WG +S GQLG +Q P+ V+ L + QVA G H
Sbjct: 146 VSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAH 205
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
S AL+ SG ++ WG N+ GQ GL + R+ H+ L + I+CG HT VL+KS
Sbjct: 206 SFALSLSGAVFGWGMNNAGQLGLSDEKDRESPC-HVKLLRTQKVVYISCGEEHTAVLTKS 264
Query: 620 RCGFWMG 640
F G
Sbjct: 265 GGVFTFG 271
Score = 81.8 bits (193), Expect = 2e-15
Identities = 44/118 (37%), Positives = 68/118 (57%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG HS+ + E G+ ++ G ++ GQLG+ +KP+ + LA +++I VACG H
Sbjct: 43 VACGGNHSVFLLEDGEVYTCGLNTKGQLGHE---REGNKPEQIGALADQHIIHVACGESH 99
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
S+AL++ G L+SWGA S GQ GL + + I L I ++CGN H L+
Sbjct: 100 SLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALA 157
Score = 75.8 bits (178), Expect = 1e-13
Identities = 40/120 (33%), Positives = 63/120 (52%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+A G HS A+ G F WG ++ GQLG + ++ P VK L T+ V+ ++CG H
Sbjct: 199 VAAGGAHSFALSLSGAVFGWGMNNAGQLGLS-DEKDRESPCHVKLLRTQKVVYISCGEEH 257
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
+ LT SG ++++GA S GQ G + + + + + L+G + I CG HT S
Sbjct: 258 TAVLTKSGGVFTFGAGSCGQLGHDSMND-EVNPRRVLELMGSEVTQIACGRQHTLAFVPS 316
Score = 56.8 bits (131), Expect = 7e-08
Identities = 29/83 (34%), Positives = 51/83 (61%), Gaps = 1/83 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
I+CG +H+ + + G F++G+ S GQLG++ + + P+ V L V Q+ACG H
Sbjct: 251 ISCGEEHTAVLTKSGGVFTFGAGSCGQLGHD-SMNDEVNPRRVLELMGSEVTQIACGRQH 309
Query: 440 SVA-LTNSGDLYSWGANSYGQCG 505
++A + +SG +Y++G + GQ G
Sbjct: 310 TLAFVPSSGLIYAFGCGARGQLG 332
Score = 54.0 bits (124), Expect = 5e-07
Identities = 32/100 (32%), Positives = 51/100 (51%), Gaps = 1/100 (1%)
Frame = +2
Query: 317 WGSDSMGQLGNNLGAHA-QDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSY 493
WG S+GQ G + +P+ ++ ++V +VACG HSV L G++Y+ G N+
Sbjct: 8 WGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGLNTK 67
Query: 494 GQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
GQ G E + + I +L I + CG +H+ LS
Sbjct: 68 GQLGHEREGNKP---EQIGALADQHIIHVACGESHSLALS 104
Score = 47.6 bits (108), Expect = 4e-05
Identities = 26/57 (45%), Positives = 31/57 (54%)
Frame = +3
Query: 90 HIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIRQ 260
HI VA GE HSL LS+ G L+S G GQLG T D+ P L++ TI Q
Sbjct: 89 HIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQ 145
Score = 41.9 bits (94), Expect = 0.002
Identities = 18/58 (31%), Positives = 32/58 (55%)
Frame = +3
Query: 33 SQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESD 206
+ + +V +P + + ++ VA G HS++L G +Y+CG N GQLG + E +
Sbjct: 20 TNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGLNTKGQLGHEREGN 77
Score = 36.3 bits (80), Expect = 0.10
Identities = 20/47 (42%), Positives = 27/47 (57%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFK 242
VAAG HS LS SG ++ G N+ GQLG E D ++P V+ +
Sbjct: 199 VAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDR-ESPCHVKLLR 244
Score = 35.9 bits (79), Expect = 0.14
Identities = 21/72 (29%), Positives = 32/72 (44%)
Frame = +3
Query: 45 DLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPA 224
D V P L + I V+ G +H L L+ G ++ G N GQLG E + +P
Sbjct: 127 DSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQ 186
Query: 225 LVETFKDCTIRQ 260
V + + + Q
Sbjct: 187 RVRSLEGIPLAQ 198
Score = 31.9 bits (69), Expect = 2.2
Identities = 26/75 (34%), Positives = 37/75 (49%), Gaps = 5/75 (6%)
Frame = +2
Query: 254 TTIACGLQHSLA-IDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACG 430
T IACG QH+LA + G +++G + GQLG + + P VKG + Q++
Sbjct: 301 TQIACGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVK-CPSPVKGYWAAHSGQLSAR 359
Query: 431 A----YHSVALTNSG 463
A YH V SG
Sbjct: 360 ADRFKYHIVKQIFSG 374
>BC038960-1|AAH38960.1| 368|Homo sapiens HERC3 protein protein.
Length = 368
Score = 105 bits (253), Expect = 1e-22
Identities = 51/131 (38%), Positives = 74/131 (56%)
Frame = +2
Query: 248 HNTTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 427
H +ACG HSLA+ + GQ FSWG+ S GQLG + P+ ++ L + ++QV+C
Sbjct: 85 HIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSC 144
Query: 428 GAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFV 607
G +H +AL G ++WG NS+GQ GL + Q + SL G+P+A + G H+F
Sbjct: 145 GNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFA 204
Query: 608 LSKSRCGFWMG 640
LS S F G
Sbjct: 205 LSLSGAVFGWG 215
Score = 88.2 bits (209), Expect = 2e-17
Identities = 50/127 (39%), Positives = 69/127 (54%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
++CG H LA+ GQ F+WG +S GQLG +Q P+ V+ L + QVA G H
Sbjct: 142 VSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAH 201
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
S AL+ SG ++ WG N+ GQ GL + R+ H+ L + I+CG HT VL+KS
Sbjct: 202 SFALSLSGAVFGWGMNNAGQLGLSDEKDRESPC-HVKLLRTQKVVYISCGEEHTAVLTKS 260
Query: 620 RCGFWMG 640
F G
Sbjct: 261 GGVFTFG 267
Score = 81.8 bits (193), Expect = 2e-15
Identities = 44/118 (37%), Positives = 68/118 (57%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG HS+ + E G+ ++ G ++ GQLG+ +KP+ + LA +++I VACG H
Sbjct: 39 VACGGNHSVFLLEDGEVYTCGLNTKGQLGHE---REGNKPEQIGALADQHIIHVACGESH 95
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
S+AL++ G L+SWGA S GQ GL + + I L I ++CGN H L+
Sbjct: 96 SLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALA 153
Score = 75.8 bits (178), Expect = 1e-13
Identities = 40/120 (33%), Positives = 63/120 (52%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+A G HS A+ G F WG ++ GQLG + ++ P VK L T+ V+ ++CG H
Sbjct: 195 VAAGGAHSFALSLSGAVFGWGMNNAGQLGLS-DEKDRESPCHVKLLRTQKVVYISCGEEH 253
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
+ LT SG ++++GA S GQ G + + + + + L+G + I CG HT S
Sbjct: 254 TAVLTKSGGVFTFGAGSCGQLGHDSMND-EVNPRRVLELMGSEVTQIACGRQHTLAFVPS 312
Score = 56.8 bits (131), Expect = 7e-08
Identities = 29/83 (34%), Positives = 51/83 (61%), Gaps = 1/83 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
I+CG +H+ + + G F++G+ S GQLG++ + + P+ V L V Q+ACG H
Sbjct: 247 ISCGEEHTAVLTKSGGVFTFGAGSCGQLGHD-SMNDEVNPRRVLELMGSEVTQIACGRQH 305
Query: 440 SVA-LTNSGDLYSWGANSYGQCG 505
++A + +SG +Y++G + GQ G
Sbjct: 306 TLAFVPSSGLIYAFGCGARGQLG 328
Score = 54.0 bits (124), Expect = 5e-07
Identities = 32/100 (32%), Positives = 51/100 (51%), Gaps = 1/100 (1%)
Frame = +2
Query: 317 WGSDSMGQLGNNLGAHA-QDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSY 493
WG S+GQ G + +P+ ++ ++V +VACG HSV L G++Y+ G N+
Sbjct: 4 WGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGLNTK 63
Query: 494 GQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
GQ G E + + I +L I + CG +H+ LS
Sbjct: 64 GQLGHEREGNKP---EQIGALADQHIIHVACGESHSLALS 100
Score = 47.6 bits (108), Expect = 4e-05
Identities = 26/57 (45%), Positives = 31/57 (54%)
Frame = +3
Query: 90 HIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIRQ 260
HI VA GE HSL LS+ G L+S G GQLG T D+ P L++ TI Q
Sbjct: 85 HIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQ 141
Score = 41.9 bits (94), Expect = 0.002
Identities = 18/58 (31%), Positives = 32/58 (55%)
Frame = +3
Query: 33 SQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESD 206
+ + +V +P + + ++ VA G HS++L G +Y+CG N GQLG + E +
Sbjct: 16 TNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGLNTKGQLGHEREGN 73
Score = 36.3 bits (80), Expect = 0.10
Identities = 20/47 (42%), Positives = 27/47 (57%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFK 242
VAAG HS LS SG ++ G N+ GQLG E D ++P V+ +
Sbjct: 195 VAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDR-ESPCHVKLLR 240
Score = 35.9 bits (79), Expect = 0.14
Identities = 21/72 (29%), Positives = 32/72 (44%)
Frame = +3
Query: 45 DLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPA 224
D V P L + I V+ G +H L L+ G ++ G N GQLG E + +P
Sbjct: 123 DSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQ 182
Query: 225 LVETFKDCTIRQ 260
V + + + Q
Sbjct: 183 RVRSLEGIPLAQ 194
Score = 31.5 bits (68), Expect = 2.9
Identities = 23/69 (33%), Positives = 35/69 (50%), Gaps = 1/69 (1%)
Frame = +2
Query: 254 TTIACGLQHSLA-IDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACG 430
T IACG QH+LA + G +++G + GQLG + + P VKG + Q++
Sbjct: 297 TQIACGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVK-CPSPVKGYWAAHSGQLSAR 355
Query: 431 AYHSVALTN 457
A + L N
Sbjct: 356 AGKNDCLWN 364
>AC098582-1|AAY41038.1| 382|Homo sapiens unknown protein.
Length = 382
Score = 105 bits (253), Expect = 1e-22
Identities = 51/131 (38%), Positives = 74/131 (56%)
Frame = +2
Query: 248 HNTTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 427
H +ACG HSLA+ + GQ FSWG+ S GQLG + P+ ++ L + ++QV+C
Sbjct: 85 HIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSC 144
Query: 428 GAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFV 607
G +H +AL G ++WG NS+GQ GL + Q + SL G+P+A + G H+F
Sbjct: 145 GNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFA 204
Query: 608 LSKSRCGFWMG 640
LS S F G
Sbjct: 205 LSLSGAVFGWG 215
Score = 88.2 bits (209), Expect = 2e-17
Identities = 50/127 (39%), Positives = 69/127 (54%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
++CG H LA+ GQ F+WG +S GQLG +Q P+ V+ L + QVA G H
Sbjct: 142 VSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAH 201
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
S AL+ SG ++ WG N+ GQ GL + R+ H+ L + I+CG HT VL+KS
Sbjct: 202 SFALSLSGAVFGWGMNNAGQLGLSDEKDRESPC-HVKLLRTQKVVYISCGEEHTAVLTKS 260
Query: 620 RCGFWMG 640
F G
Sbjct: 261 GGVFTFG 267
Score = 81.8 bits (193), Expect = 2e-15
Identities = 44/118 (37%), Positives = 68/118 (57%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG HS+ + E G+ ++ G ++ GQLG+ +KP+ + LA +++I VACG H
Sbjct: 39 VACGGNHSVFLLEDGEVYTCGLNTKGQLGHE---REGNKPEQIGALADQHIIHVACGESH 95
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
S+AL++ G L+SWGA S GQ GL + + I L I ++CGN H L+
Sbjct: 96 SLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALA 153
Score = 75.8 bits (178), Expect = 1e-13
Identities = 40/120 (33%), Positives = 63/120 (52%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+A G HS A+ G F WG ++ GQLG + ++ P VK L T+ V+ ++CG H
Sbjct: 195 VAAGGAHSFALSLSGAVFGWGMNNAGQLGLS-DEKDRESPCHVKLLRTQKVVYISCGEEH 253
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
+ LT SG ++++GA S GQ G + + + + + L+G + I CG HT S
Sbjct: 254 TAVLTKSGGVFTFGAGSCGQLGHDSMND-EVNPRRVLELMGSEVTQIACGRQHTLAFVPS 312
Score = 56.8 bits (131), Expect = 7e-08
Identities = 29/83 (34%), Positives = 51/83 (61%), Gaps = 1/83 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
I+CG +H+ + + G F++G+ S GQLG++ + + P+ V L V Q+ACG H
Sbjct: 247 ISCGEEHTAVLTKSGGVFTFGAGSCGQLGHD-SMNDEVNPRRVLELMGSEVTQIACGRQH 305
Query: 440 SVA-LTNSGDLYSWGANSYGQCG 505
++A + +SG +Y++G + GQ G
Sbjct: 306 TLAFVPSSGLIYAFGCGARGQLG 328
Score = 54.0 bits (124), Expect = 5e-07
Identities = 32/100 (32%), Positives = 51/100 (51%), Gaps = 1/100 (1%)
Frame = +2
Query: 317 WGSDSMGQLGNNLGAHA-QDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSY 493
WG S+GQ G + +P+ ++ ++V +VACG HSV L G++Y+ G N+
Sbjct: 4 WGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGLNTK 63
Query: 494 GQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
GQ G E + + I +L I + CG +H+ LS
Sbjct: 64 GQLGHEREGNKP---EQIGALADQHIIHVACGESHSLALS 100
Score = 47.6 bits (108), Expect = 4e-05
Identities = 26/57 (45%), Positives = 31/57 (54%)
Frame = +3
Query: 90 HIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIRQ 260
HI VA GE HSL LS+ G L+S G GQLG T D+ P L++ TI Q
Sbjct: 85 HIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQ 141
Score = 41.9 bits (94), Expect = 0.002
Identities = 18/58 (31%), Positives = 32/58 (55%)
Frame = +3
Query: 33 SQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESD 206
+ + +V +P + + ++ VA G HS++L G +Y+CG N GQLG + E +
Sbjct: 16 TNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGLNTKGQLGHEREGN 73
Score = 36.3 bits (80), Expect = 0.10
Identities = 20/47 (42%), Positives = 27/47 (57%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFK 242
VAAG HS LS SG ++ G N+ GQLG E D ++P V+ +
Sbjct: 195 VAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDR-ESPCHVKLLR 240
Score = 35.9 bits (79), Expect = 0.14
Identities = 21/72 (29%), Positives = 32/72 (44%)
Frame = +3
Query: 45 DLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPA 224
D V P L + I V+ G +H L L+ G ++ G N GQLG E + +P
Sbjct: 123 DSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQ 182
Query: 225 LVETFKDCTIRQ 260
V + + + Q
Sbjct: 183 RVRSLEGIPLAQ 194
Score = 31.9 bits (69), Expect = 2.2
Identities = 26/75 (34%), Positives = 37/75 (49%), Gaps = 5/75 (6%)
Frame = +2
Query: 254 TTIACGLQHSLA-IDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACG 430
T IACG QH+LA + G +++G + GQLG + + P VKG + Q++
Sbjct: 297 TQIACGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVK-CPSPVKGYWAAHSGQLSAR 355
Query: 431 A----YHSVALTNSG 463
A YH V SG
Sbjct: 356 ADRFKYHIVKQIFSG 370
>BC042047-1|AAH42047.2| 1022|Homo sapiens hect domain and RLD 6
protein.
Length = 1022
Score = 103 bits (246), Expect = 8e-22
Identities = 50/127 (39%), Positives = 71/127 (55%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
++CG +HSLA+ G+ F+WG+ S GQLG PK + L +IQV+CG YH
Sbjct: 80 VSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYH 139
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
S+AL+ ++SWG NS+GQ GL + Q + SL G+P+A + G H+F LS
Sbjct: 140 SLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLC 199
Query: 620 RCGFWMG 640
F G
Sbjct: 200 GTSFGWG 206
Score = 79.8 bits (188), Expect = 8e-15
Identities = 46/129 (35%), Positives = 67/129 (51%), Gaps = 2/129 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
++CG HSLA+ + Q FSWG +S GQLG +Q P+ V+ L + QVA G H
Sbjct: 133 VSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAH 192
Query: 440 SVALTNSGDLYSWGANSYGQCGL--ELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
S AL+ G + WG+NS GQ L + + +L + + I+CG+ HT VL+
Sbjct: 193 SFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVYISCGDAHTAVLT 252
Query: 614 KSRCGFWMG 640
+ F G
Sbjct: 253 QDGKVFTFG 261
Score = 73.3 bits (172), Expect = 7e-13
Identities = 43/126 (34%), Positives = 68/126 (53%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 442
A G +HSL + + S G +S GQLG GA + P+ ++ L T V V+CG HS
Sbjct: 29 ASGERHSLLLLTNHRVLSCGDNSRGQLGRR-GAQRGELPEPIQALETLIVDLVSCGKEHS 87
Query: 443 VALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKSR 622
+A+ + G +++WGA S GQ G+ ++ + I +L + I ++CG+ H+ LSK
Sbjct: 88 LAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDS 147
Query: 623 CGFWMG 640
F G
Sbjct: 148 QVFSWG 153
Score = 65.7 bits (153), Expect = 1e-10
Identities = 40/117 (34%), Positives = 60/117 (51%), Gaps = 3/117 (2%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQL---GNNLGAHAQDKPKFVKGLATKNVIQVACG 430
+A G HS A+ G F WGS+S GQL G N+ + +KP V L V+ ++CG
Sbjct: 186 VAAGGAHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQS-NKPLSVGALKNLGVVYISCG 244
Query: 431 AYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHT 601
H+ LT G ++++G N GQ G K Q + + G+ ++ I CG+ HT
Sbjct: 245 DAHTAVLTQDGKVFTFGDNRSGQLGYS-PTPEKRGPQLVERIDGL-VSQIDCGSYHT 299
Score = 40.3 bits (90), Expect = 0.006
Identities = 23/75 (30%), Positives = 44/75 (58%), Gaps = 1/75 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
I+CG H+ + + G+ F++G + GQLG + + P+ V+ + V Q+ CG+YH
Sbjct: 241 ISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRG-PQLVERIDGL-VSQIDCGSYH 298
Query: 440 SVALTN-SGDLYSWG 481
++A + +G + S+G
Sbjct: 299 TLAYVHTTGQVVSFG 313
Score = 36.7 bits (81), Expect = 0.078
Identities = 18/53 (33%), Positives = 27/53 (50%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIRQ 260
V+ G +HSL LS ++S G N GQLG E + +P V + + + Q
Sbjct: 133 VSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQ 185
Score = 36.3 bits (80), Expect = 0.10
Identities = 18/46 (39%), Positives = 28/46 (60%)
Frame = +3
Query: 105 AAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFK 242
A+GE HSL L + + SCG+N GQLGR+ + G+ P ++ +
Sbjct: 29 ASGERHSLLLLTNHRVLSCGDNSRGQLGRR-GAQRGELPEPIQALE 73
Score = 31.1 bits (67), Expect = 3.9
Identities = 14/44 (31%), Positives = 26/44 (59%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 233
++ G+ H+ L+ G +++ G+N GQLG + + + P LVE
Sbjct: 241 ISCGDAHTAVLTQDGKVFTFGDNRSGQLG-YSPTPEKRGPQLVE 283
Score = 30.3 bits (65), Expect = 6.8
Identities = 16/56 (28%), Positives = 26/56 (46%)
Frame = +3
Query: 93 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIRQ 260
+ V+ G+ HSL + + G +++ G GQLG + P + T D I Q
Sbjct: 77 VDLVSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQ 132
>AY653203-1|AAV66897.1| 322|Homo sapiens truncated HERC6 protein.
Length = 322
Score = 103 bits (246), Expect = 8e-22
Identities = 50/127 (39%), Positives = 71/127 (55%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
++CG +HSLA+ G+ F+WG+ S GQLG PK + L +IQV+CG YH
Sbjct: 80 VSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYH 139
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
S+AL+ ++SWG NS+GQ GL + Q + SL G+P+A + G H+F LS
Sbjct: 140 SLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLC 199
Query: 620 RCGFWMG 640
F G
Sbjct: 200 GTSFGWG 206
Score = 79.8 bits (188), Expect = 8e-15
Identities = 46/129 (35%), Positives = 67/129 (51%), Gaps = 2/129 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
++CG HSLA+ + Q FSWG +S GQLG +Q P+ V+ L + QVA G H
Sbjct: 133 VSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAH 192
Query: 440 SVALTNSGDLYSWGANSYGQCGL--ELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
S AL+ G + WG+NS GQ L + + +L + + I+CG+ HT VL+
Sbjct: 193 SFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVYISCGDAHTAVLT 252
Query: 614 KSRCGFWMG 640
+ F G
Sbjct: 253 QDGKVFTFG 261
Score = 73.3 bits (172), Expect = 7e-13
Identities = 43/126 (34%), Positives = 68/126 (53%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 442
A G +HSL + + S G +S GQLG GA + P+ ++ L T V V+CG HS
Sbjct: 29 ASGERHSLLLLTNHRVLSCGDNSRGQLGRR-GAQRGELPEPIQALETLIVDLVSCGKEHS 87
Query: 443 VALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKSR 622
+A+ + G +++WGA S GQ G+ ++ + I +L + I ++CG+ H+ LSK
Sbjct: 88 LAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDS 147
Query: 623 CGFWMG 640
F G
Sbjct: 148 QVFSWG 153
Score = 61.3 bits (142), Expect = 3e-09
Identities = 32/85 (37%), Positives = 46/85 (54%), Gaps = 3/85 (3%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQL---GNNLGAHAQDKPKFVKGLATKNVIQVACG 430
+A G HS A+ G F WGS+S GQL G N+ + +KP V L V+ ++CG
Sbjct: 186 VAAGGAHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQS-NKPLSVGALKNLGVVYISCG 244
Query: 431 AYHSVALTNSGDLYSWGANSYGQCG 505
H+ LT G ++++G N GQ G
Sbjct: 245 DAHTAVLTQDGKVFTFGDNRSGQLG 269
Score = 36.7 bits (81), Expect = 0.078
Identities = 18/53 (33%), Positives = 27/53 (50%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIRQ 260
V+ G +HSL LS ++S G N GQLG E + +P V + + + Q
Sbjct: 133 VSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQ 185
Score = 36.3 bits (80), Expect = 0.10
Identities = 18/46 (39%), Positives = 28/46 (60%)
Frame = +3
Query: 105 AAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFK 242
A+GE HSL L + + SCG+N GQLGR+ + G+ P ++ +
Sbjct: 29 ASGERHSLLLLTNHRVLSCGDNSRGQLGRR-GAQRGELPEPIQALE 73
Score = 31.1 bits (67), Expect = 3.9
Identities = 14/44 (31%), Positives = 26/44 (59%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 233
++ G+ H+ L+ G +++ G+N GQLG + + + P LVE
Sbjct: 241 ISCGDAHTAVLTQDGKVFTFGDNRSGQLG-YSPTPEKRGPQLVE 283
Score = 30.3 bits (65), Expect = 6.8
Identities = 16/56 (28%), Positives = 26/56 (46%)
Frame = +3
Query: 93 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIRQ 260
+ V+ G+ HSL + + G +++ G GQLG + P + T D I Q
Sbjct: 77 VDLVSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQ 132
>AY653202-1|AAV66896.1| 364|Homo sapiens truncated HERC6 protein.
Length = 364
Score = 103 bits (246), Expect = 8e-22
Identities = 50/127 (39%), Positives = 71/127 (55%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
++CG +HSLA+ G+ F+WG+ S GQLG PK + L +IQV+CG YH
Sbjct: 80 VSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYH 139
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
S+AL+ ++SWG NS+GQ GL + Q + SL G+P+A + G H+F LS
Sbjct: 140 SLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLC 199
Query: 620 RCGFWMG 640
F G
Sbjct: 200 GTSFGWG 206
Score = 79.8 bits (188), Expect = 8e-15
Identities = 46/129 (35%), Positives = 67/129 (51%), Gaps = 2/129 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
++CG HSLA+ + Q FSWG +S GQLG +Q P+ V+ L + QVA G H
Sbjct: 133 VSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAH 192
Query: 440 SVALTNSGDLYSWGANSYGQCGL--ELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
S AL+ G + WG+NS GQ L + + +L + + I+CG+ HT VL+
Sbjct: 193 SFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVYISCGDAHTAVLT 252
Query: 614 KSRCGFWMG 640
+ F G
Sbjct: 253 QDGKVFTFG 261
Score = 73.3 bits (172), Expect = 7e-13
Identities = 43/126 (34%), Positives = 68/126 (53%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 442
A G +HSL + + S G +S GQLG GA + P+ ++ L T V V+CG HS
Sbjct: 29 ASGERHSLLLLTNHRVLSCGDNSRGQLGRR-GAQRGELPEPIQALETLIVDLVSCGKEHS 87
Query: 443 VALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKSR 622
+A+ + G +++WGA S GQ G+ ++ + I +L + I ++CG+ H+ LSK
Sbjct: 88 LAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDS 147
Query: 623 CGFWMG 640
F G
Sbjct: 148 QVFSWG 153
Score = 65.7 bits (153), Expect = 1e-10
Identities = 40/117 (34%), Positives = 60/117 (51%), Gaps = 3/117 (2%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQL---GNNLGAHAQDKPKFVKGLATKNVIQVACG 430
+A G HS A+ G F WGS+S GQL G N+ + +KP V L V+ ++CG
Sbjct: 186 VAAGGAHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQS-NKPLSVGALKNLGVVYISCG 244
Query: 431 AYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHT 601
H+ LT G ++++G N GQ G K Q + + G+ ++ I CG+ HT
Sbjct: 245 DAHTAVLTQDGKVFTFGDNRSGQLGYS-PTPEKRGPQLVERIDGL-VSQIDCGSYHT 299
Score = 40.3 bits (90), Expect = 0.006
Identities = 23/75 (30%), Positives = 44/75 (58%), Gaps = 1/75 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
I+CG H+ + + G+ F++G + GQLG + + P+ V+ + V Q+ CG+YH
Sbjct: 241 ISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRG-PQLVERIDGL-VSQIDCGSYH 298
Query: 440 SVALTN-SGDLYSWG 481
++A + +G + S+G
Sbjct: 299 TLAYVHTTGQVVSFG 313
Score = 36.7 bits (81), Expect = 0.078
Identities = 18/53 (33%), Positives = 27/53 (50%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIRQ 260
V+ G +HSL LS ++S G N GQLG E + +P V + + + Q
Sbjct: 133 VSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQ 185
Score = 36.3 bits (80), Expect = 0.10
Identities = 18/46 (39%), Positives = 28/46 (60%)
Frame = +3
Query: 105 AAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFK 242
A+GE HSL L + + SCG+N GQLGR+ + G+ P ++ +
Sbjct: 29 ASGERHSLLLLTNHRVLSCGDNSRGQLGRR-GAQRGELPEPIQALE 73
Score = 31.1 bits (67), Expect = 3.9
Identities = 14/44 (31%), Positives = 26/44 (59%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 233
++ G+ H+ L+ G +++ G+N GQLG + + + P LVE
Sbjct: 241 ISCGDAHTAVLTQDGKVFTFGDNRSGQLG-YSPTPEKRGPQLVE 283
Score = 30.3 bits (65), Expect = 6.8
Identities = 16/56 (28%), Positives = 26/56 (46%)
Frame = +3
Query: 93 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIRQ 260
+ V+ G+ HSL + + G +++ G GQLG + P + T D I Q
Sbjct: 77 VDLVSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQ 132
>AY653201-1|AAV66895.1| 986|Homo sapiens HERC6 splice variant
protein.
Length = 986
Score = 103 bits (246), Expect = 8e-22
Identities = 50/127 (39%), Positives = 71/127 (55%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
++CG +HSLA+ G+ F+WG+ S GQLG PK + L +IQV+CG YH
Sbjct: 80 VSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYH 139
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
S+AL+ ++SWG NS+GQ GL + Q + SL G+P+A + G H+F LS
Sbjct: 140 SLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLC 199
Query: 620 RCGFWMG 640
F G
Sbjct: 200 GTSFGWG 206
Score = 79.8 bits (188), Expect = 8e-15
Identities = 46/129 (35%), Positives = 67/129 (51%), Gaps = 2/129 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
++CG HSLA+ + Q FSWG +S GQLG +Q P+ V+ L + QVA G H
Sbjct: 133 VSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAH 192
Query: 440 SVALTNSGDLYSWGANSYGQCGL--ELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
S AL+ G + WG+NS GQ L + + +L + + I+CG+ HT VL+
Sbjct: 193 SFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVYISCGDAHTAVLT 252
Query: 614 KSRCGFWMG 640
+ F G
Sbjct: 253 QDGKVFTFG 261
Score = 73.3 bits (172), Expect = 7e-13
Identities = 43/126 (34%), Positives = 68/126 (53%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 442
A G +HSL + + S G +S GQLG GA + P+ ++ L T V V+CG HS
Sbjct: 29 ASGERHSLLLLTNHRVLSCGDNSRGQLGRR-GAQRGELPEPIQALETLIVDLVSCGKEHS 87
Query: 443 VALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKSR 622
+A+ + G +++WGA S GQ G+ ++ + I +L + I ++CG+ H+ LSK
Sbjct: 88 LAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDS 147
Query: 623 CGFWMG 640
F G
Sbjct: 148 QVFSWG 153
Score = 65.7 bits (153), Expect = 1e-10
Identities = 40/117 (34%), Positives = 60/117 (51%), Gaps = 3/117 (2%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQL---GNNLGAHAQDKPKFVKGLATKNVIQVACG 430
+A G HS A+ G F WGS+S GQL G N+ + +KP V L V+ ++CG
Sbjct: 186 VAAGGAHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQS-NKPLSVGALKNLGVVYISCG 244
Query: 431 AYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHT 601
H+ LT G ++++G N GQ G K Q + + G+ ++ I CG+ HT
Sbjct: 245 DAHTAVLTQDGKVFTFGDNRSGQLGYS-PTPEKRGPQLVERIDGL-VSQIDCGSYHT 299
Score = 40.3 bits (90), Expect = 0.006
Identities = 23/75 (30%), Positives = 44/75 (58%), Gaps = 1/75 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
I+CG H+ + + G+ F++G + GQLG + + P+ V+ + V Q+ CG+YH
Sbjct: 241 ISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRG-PQLVERIDGL-VSQIDCGSYH 298
Query: 440 SVALTN-SGDLYSWG 481
++A + +G + S+G
Sbjct: 299 TLAYVHTTGQVVSFG 313
Score = 36.7 bits (81), Expect = 0.078
Identities = 18/53 (33%), Positives = 27/53 (50%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIRQ 260
V+ G +HSL LS ++S G N GQLG E + +P V + + + Q
Sbjct: 133 VSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQ 185
Score = 36.3 bits (80), Expect = 0.10
Identities = 18/46 (39%), Positives = 28/46 (60%)
Frame = +3
Query: 105 AAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFK 242
A+GE HSL L + + SCG+N GQLGR+ + G+ P ++ +
Sbjct: 29 ASGERHSLLLLTNHRVLSCGDNSRGQLGRR-GAQRGELPEPIQALE 73
Score = 31.1 bits (67), Expect = 3.9
Identities = 14/44 (31%), Positives = 26/44 (59%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 233
++ G+ H+ L+ G +++ G+N GQLG + + + P LVE
Sbjct: 241 ISCGDAHTAVLTQDGKVFTFGDNRSGQLG-YSPTPEKRGPQLVE 283
Score = 30.3 bits (65), Expect = 6.8
Identities = 16/56 (28%), Positives = 26/56 (46%)
Frame = +3
Query: 93 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIRQ 260
+ V+ G+ HSL + + G +++ G GQLG + P + T D I Q
Sbjct: 77 VDLVSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQ 132
>AF336798-1|AAQ14893.1| 1022|Homo sapiens HERC6 protein.
Length = 1022
Score = 103 bits (246), Expect = 8e-22
Identities = 50/127 (39%), Positives = 71/127 (55%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
++CG +HSLA+ G+ F+WG+ S GQLG PK + L +IQV+CG YH
Sbjct: 80 VSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYH 139
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
S+AL+ ++SWG NS+GQ GL + Q + SL G+P+A + G H+F LS
Sbjct: 140 SLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLC 199
Query: 620 RCGFWMG 640
F G
Sbjct: 200 GTSFGWG 206
Score = 79.8 bits (188), Expect = 8e-15
Identities = 46/129 (35%), Positives = 67/129 (51%), Gaps = 2/129 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
++CG HSLA+ + Q FSWG +S GQLG +Q P+ V+ L + QVA G H
Sbjct: 133 VSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAH 192
Query: 440 SVALTNSGDLYSWGANSYGQCGL--ELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
S AL+ G + WG+NS GQ L + + +L + + I+CG+ HT VL+
Sbjct: 193 SFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVYISCGDAHTAVLT 252
Query: 614 KSRCGFWMG 640
+ F G
Sbjct: 253 QDGKVFTFG 261
Score = 73.3 bits (172), Expect = 7e-13
Identities = 43/126 (34%), Positives = 68/126 (53%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 442
A G +HSL + + S G +S GQLG GA + P+ ++ L T V V+CG HS
Sbjct: 29 ASGERHSLLLLTNHRVLSCGDNSRGQLGRR-GAQRGELPEPIQALETLIVDLVSCGKEHS 87
Query: 443 VALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKSR 622
+A+ + G +++WGA S GQ G+ ++ + I +L + I ++CG+ H+ LSK
Sbjct: 88 LAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDS 147
Query: 623 CGFWMG 640
F G
Sbjct: 148 QVFSWG 153
Score = 65.7 bits (153), Expect = 1e-10
Identities = 40/117 (34%), Positives = 60/117 (51%), Gaps = 3/117 (2%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQL---GNNLGAHAQDKPKFVKGLATKNVIQVACG 430
+A G HS A+ G F WGS+S GQL G N+ + +KP V L V+ ++CG
Sbjct: 186 VAAGGAHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQS-NKPLSVGALKNLGVVYISCG 244
Query: 431 AYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHT 601
H+ LT G ++++G N GQ G K Q + + G+ ++ I CG+ HT
Sbjct: 245 DAHTAVLTQDGKVFTFGDNRSGQLGYS-PTPEKRGPQLVERIDGL-VSQIDCGSYHT 299
Score = 40.3 bits (90), Expect = 0.006
Identities = 23/75 (30%), Positives = 44/75 (58%), Gaps = 1/75 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
I+CG H+ + + G+ F++G + GQLG + + P+ V+ + V Q+ CG+YH
Sbjct: 241 ISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRG-PQLVERIDGL-VSQIDCGSYH 298
Query: 440 SVALTN-SGDLYSWG 481
++A + +G + S+G
Sbjct: 299 TLAYVHTTGQVVSFG 313
Score = 36.7 bits (81), Expect = 0.078
Identities = 18/53 (33%), Positives = 27/53 (50%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIRQ 260
V+ G +HSL LS ++S G N GQLG E + +P V + + + Q
Sbjct: 133 VSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQ 185
Score = 36.3 bits (80), Expect = 0.10
Identities = 18/46 (39%), Positives = 28/46 (60%)
Frame = +3
Query: 105 AAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFK 242
A+GE HSL L + + SCG+N GQLGR+ + G+ P ++ +
Sbjct: 29 ASGERHSLLLLTNHRVLSCGDNSRGQLGRR-GAQRGELPEPIQALE 73
Score = 31.1 bits (67), Expect = 3.9
Identities = 14/44 (31%), Positives = 26/44 (59%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 233
++ G+ H+ L+ G +++ G+N GQLG + + + P LVE
Sbjct: 241 ISCGDAHTAVLTQDGKVFTFGDNRSGQLG-YSPTPEKRGPQLVE 283
Score = 30.3 bits (65), Expect = 6.8
Identities = 16/56 (28%), Positives = 26/56 (46%)
Frame = +3
Query: 93 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIRQ 260
+ V+ G+ HSL + + G +++ G GQLG + P + T D I Q
Sbjct: 77 VDLVSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQ 132
>AB046813-1|BAB13419.1| 953|Homo sapiens KIAA1593 protein protein.
Length = 953
Score = 88.6 bits (210), Expect = 2e-17
Identities = 48/127 (37%), Positives = 62/127 (48%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG HSLA+ + + F WG + GQLG Q P+ +K L +QVA G H
Sbjct: 38 VACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAH 97
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
S LT SG ++ WG N +GQ GL R + SL I I CG +HT L+K
Sbjct: 98 SFVLTLSGAIFGWGRNKFGQLGLNDENDRYVP-NLLKSLRSQKIVYICCGEDHTAALTKE 156
Query: 620 RCGFWMG 640
F G
Sbjct: 157 GGVFTFG 163
Score = 74.9 bits (176), Expect = 2e-13
Identities = 33/85 (38%), Positives = 51/85 (60%)
Frame = +2
Query: 386 VKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGV 565
+K L+ ++QVACG YHS+AL+ + +++ WG N YGQ GL ++ Q + SL+G+
Sbjct: 27 IKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGI 86
Query: 566 PIALITCGNNHTFVLSKSRCGFWMG 640
P + G H+FVL+ S F G
Sbjct: 87 PFMQVAAGGAHSFVLTLSGAIFGWG 111
Score = 73.7 bits (173), Expect = 6e-13
Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 2/123 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+A G HS + G F WG + GQLG N + + P +K L ++ ++ + CG H
Sbjct: 91 VAAGGAHSFVLTLSGAIFGWGRNKFGQLGLN-DENDRYVPNLLKSLRSQKIVYICCGEDH 149
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHT--FVLS 613
+ ALT G ++++GA YGQ G + + + + + L+G + I CG HT FV S
Sbjct: 150 TAALTKEGGVFTFGAGGYGQLG-HNSTSHEINPRKVFELMGSIVTEIACGRQHTSAFVPS 208
Query: 614 KSR 622
R
Sbjct: 209 SGR 211
Score = 37.5 bits (83), Expect = 0.045
Identities = 18/48 (37%), Positives = 27/48 (56%)
Frame = +3
Query: 93 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVET 236
I VA G +HSL LS + ++ G N GQLG T+ +P L+++
Sbjct: 35 IVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKS 82
Score = 35.5 bits (78), Expect = 0.18
Identities = 17/35 (48%), Positives = 21/35 (60%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESD 206
VAAG HS L+ SG ++ G N GQLG E+D
Sbjct: 91 VAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDEND 125
Score = 31.1 bits (67), Expect = 3.9
Identities = 19/48 (39%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Frame = +2
Query: 254 TTIACGLQHSLA-IDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG 394
T IACG QH+ A + G+ +S+G GQLG ++ + P VKG
Sbjct: 193 TEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSN-RKSPFTVKG 239
Score = 30.3 bits (65), Expect = 6.8
Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Frame = +3
Query: 93 IQAVAAGEFH-SLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 233
+ +A G H S ++ +SG +YS G GQLG + S N K+P V+
Sbjct: 192 VTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTS-NRKSPFTVK 238
>U50078-1|AAD12586.1| 4861|Homo sapiens p532 protein.
Length = 4861
Score = 86.6 bits (205), Expect = 7e-17
Identities = 42/125 (33%), Positives = 70/125 (56%), Gaps = 1/125 (0%)
Frame = +2
Query: 263 ACGLQ-HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+CG HS+A+ E G+ FSWG G+LG+ + Q +P+ ++ L + V+Q++CG H
Sbjct: 4087 SCGSDGHSMALTESGEVFSWGDGDYGKLGHG-NSDRQRRPRQIEALQGEEVVQMSCGFKH 4145
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
S +T+ G L+++G YG+ GL +K + +++L G I + CG NHT +S
Sbjct: 4146 SAVVTSDGKLFTFGNGDYGRLGLGNTSNKKLP-ERVTALEGYQIGQVACGLNHTLAVSAD 4204
Query: 620 RCGFW 634
W
Sbjct: 4205 GSMVW 4209
Score = 72.5 bits (170), Expect = 1e-12
Identities = 42/122 (34%), Positives = 65/122 (53%), Gaps = 3/122 (2%)
Frame = +2
Query: 278 HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG-LATKNVIQVACGAYHSVALT 454
H+LA G+ FSWG G+LG+ + Q PK ++G L K V+ V+ G HS A+T
Sbjct: 469 HTLAFTTEGEVFSWGDGDYGKLGHG-NSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVT 527
Query: 455 NSGDLYSWGANSYGQCGLELYQTRKCH--LQHISSLIGVPIALITCGNNHTFVLSKSRCG 628
G+LY+WG +G+ G +R ++ IS+ + ++CG++HT LSK
Sbjct: 528 EDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDISN-----VGEVSCGSSHTIALSKDGRT 582
Query: 629 FW 634
W
Sbjct: 583 VW 584
Score = 70.1 bits (164), Expect = 7e-12
Identities = 36/114 (31%), Positives = 59/114 (51%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ G Q SLA+ GQ ++WG + LG +PK ++ LA ++ V+ G H
Sbjct: 619 VCAGSQSSLALTSTGQVYAWGCGAC--LGCGSSEATALRPKLIEELAATRIVDVSIGDSH 676
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHT 601
+AL++ ++Y+WG NS GQCG + +S L G+ I I+ G +H+
Sbjct: 677 CLALSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKVSGLDGIAIQQISAGTSHS 730
Score = 66.1 bits (154), Expect = 1e-10
Identities = 40/121 (33%), Positives = 65/121 (53%), Gaps = 2/121 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK-PKFVKGLATKNVIQVACGAY 436
++CG +HS + G+ F++G+ G+LG LG + K P+ V L + QVACG
Sbjct: 4139 MSCGFKHSAVVTSDGKLFTFGNGDYGRLG--LGNTSNKKLPERVTALEGYQIGQVACGLN 4196
Query: 437 HSVALTNSGDL-YSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
H++A++ G + +++G YG+ GL T K Q I L G+ I + CG + L+
Sbjct: 4197 HTLAVSADGSMVWAFGDGDYGKLGLG-NSTAKSSPQKIDVLCGIGIKKVACGTQFSVALT 4255
Query: 614 K 616
K
Sbjct: 4256 K 4256
Score = 64.9 bits (151), Expect = 3e-10
Identities = 39/115 (33%), Positives = 65/115 (56%), Gaps = 1/115 (0%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG Q S+A+ + G +++G D + L A ++P+ + LA + VA GA H
Sbjct: 4244 VACGTQFSVALTKDGHVYTFGQDRLIGLPEGR-ARNHNRPQQIPVLAGVIIEDVAVGAEH 4302
Query: 440 SVALTNSGDLYSWGANSYGQCGL-ELYQTRKCHLQHISSLIGVPIALITCGNNHT 601
++AL ++GD+Y+WG+NS GQ GL R+ L ++ L G + I+ G H+
Sbjct: 4303 TLALASNGDVYAWGSNSEGQLGLGHTNHVREPTL--VTGLQGKNVRQISAGRCHS 4355
Score = 57.6 bits (133), Expect = 4e-08
Identities = 33/119 (27%), Positives = 62/119 (52%), Gaps = 1/119 (0%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQP-FSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAY 436
++CG H++A+ + G+ +S+G G+LG+ + KPK ++ L + +V G+
Sbjct: 566 VSCGSSHTIALSKDGRTVWSFGGGDNGKLGHG-DTNRVYKPKVIEALQGMFIRKVCAGSQ 624
Query: 437 HSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
S+ALT++G +Y+WG + CG + + I L I ++ G++H LS
Sbjct: 625 SSLALTSTGQVYAWGCGACLGCGSS--EATALRPKLIEELAATRIVDVSIGDSHCLALS 681
Score = 57.6 bits (133), Expect = 4e-08
Identities = 40/122 (32%), Positives = 62/122 (50%), Gaps = 2/122 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQP-FSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAY 436
+ACGL H+LA+ G +++G G+LG + A+ P+ + L + +VACG
Sbjct: 4191 VACGLNHTLAVSADGSMVWAFGDGDYGKLGLG-NSTAKSSPQKIDVLCGIGIKKVACGTQ 4249
Query: 437 HSVALTNSGDLYSWGANSYGQCGLELYQTRKCHL-QHISSLIGVPIALITCGNNHTFVLS 613
SVALT G +Y++G + GL + R + Q I L GV I + G HT L+
Sbjct: 4250 FSVALTKDGHVYTFGQDRL--IGLPEGRARNHNRPQQIPVLAGVIIEDVAVGAEHTLALA 4307
Query: 614 KS 619
+
Sbjct: 4308 SN 4309
Score = 57.2 bits (132), Expect = 5e-08
Identities = 34/121 (28%), Positives = 68/121 (56%), Gaps = 1/121 (0%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
++ G +HS A+ E G+ ++WG G+LG+ +++++ P VK ++ NV +V+CG+ H
Sbjct: 516 VSAGYRHSAAVTEDGELYTWGEGDFGRLGHG-DSNSRNIPTLVKDIS--NVGEVSCGSSH 572
Query: 440 SVALTNSG-DLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSK 616
++AL+ G ++S+G G+ G R + I +L G+ I + G+ + L+
Sbjct: 573 TIALSKDGRTVWSFGGGDNGKLG-HGDTNRVYKPKVIEALQGMFIRKVCAGSQSSLALTS 631
Query: 617 S 619
+
Sbjct: 632 T 632
Score = 56.0 bits (129), Expect = 1e-07
Identities = 37/130 (28%), Positives = 62/130 (47%), Gaps = 3/130 (2%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLG--NNLGAHAQDKPKFVKGLATKNVIQVACGA 433
+ CG + I G + G S G+LG N+ H ++G ++ +CG+
Sbjct: 4032 VICGQNCTFVIQANGTVLACGEGSYGRLGQGNSDDLHVLTVISALQGFVVTQLV-TSCGS 4090
Query: 434 Y-HSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVL 610
HS+ALT SG+++SWG YG+ G R+ + I +L G + ++CG H+ V+
Sbjct: 4091 DGHSMALTESGEVFSWGDGDYGKLG-HGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVV 4149
Query: 611 SKSRCGFWMG 640
+ F G
Sbjct: 4150 TSDGKLFTFG 4159
Score = 55.6 bits (128), Expect = 2e-07
Identities = 28/65 (43%), Positives = 39/65 (60%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+A G +H+LA+ G ++WGS+S GQLG H ++ P V GL KNV Q++ G H
Sbjct: 4296 VAVGAEHTLALASNGDVYAWGSNSEGQLGLGHTNHVRE-PTLVTGLQGKNVRQISAGRCH 4354
Query: 440 SVALT 454
S A T
Sbjct: 4355 SAAWT 4359
Score = 47.6 bits (108), Expect = 4e-05
Identities = 23/65 (35%), Positives = 35/65 (53%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
++ G H LA+ + ++WG++SMGQ G KPK V GL + Q++ G H
Sbjct: 670 VSIGDSHCLALSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKVSGLDGIAIQQISAGTSH 729
Query: 440 SVALT 454
S+A T
Sbjct: 730 SLAWT 734
Score = 38.3 bits (85), Expect = 0.026
Identities = 20/56 (35%), Positives = 34/56 (60%)
Frame = +3
Query: 93 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIRQ 260
I+ VA G H+L L+++G +Y+ G+N GQLG +++ + P LV + +RQ
Sbjct: 4293 IEDVAVGAEHTLALASNGDVYAWGSNSEGQLG-LGHTNHVREPTLVTGLQGKNVRQ 4347
Score = 37.5 bits (83), Expect = 0.045
Identities = 21/80 (26%), Positives = 35/80 (43%)
Frame = +3
Query: 21 CIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE 200
C+ ++P L + + I V+ G+ H L LS+ +Y+ GNN +GQ G+
Sbjct: 643 CLGCGSSEATALRPKLIEELAATRIVDVSIGDSHCLALSHDNEVYAWGNNSMGQCGQGNS 702
Query: 201 SDNGKNPALVETFKDCTIRQ 260
+ P V I+Q
Sbjct: 703 TGPITKPKKVSGLDGIAIQQ 722
Score = 31.5 bits (68), Expect = 2.9
Identities = 18/59 (30%), Positives = 35/59 (59%)
Frame = +3
Query: 12 HELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG 188
H+L ++G+Q + +++P L+ SD Q + AG++ + +S G + +CG G+LG
Sbjct: 383 HQL-VEGTQ--EKILQPKLAP-SFSD-AQTIEAGQYCTFVISTDGSVRACGKGSYGRLG 436
Score = 30.7 bits (66), Expect = 5.1
Identities = 19/73 (26%), Positives = 32/73 (43%)
Frame = +2
Query: 290 IDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDL 469
+ E + + WGS+S QL +PK + I+ G Y + ++ G +
Sbjct: 368 VSETCEVYVWGSNSSHQLVEGTQEKIL-QPKLAPSFSDAQTIEA--GQYCTFVISTDGSV 424
Query: 470 YSWGANSYGQCGL 508
+ G SYG+ GL
Sbjct: 425 RACGKGSYGRLGL 437
>AB027289-1|BAA88519.1| 1024|Homo sapiens cyclin-E binding protein 1
protein.
Length = 1024
Score = 84.2 bits (199), Expect = 4e-16
Identities = 45/127 (35%), Positives = 68/127 (53%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
I CG HSLA+ + G+ F+WG + GQLG + P+ V+ LA + Q++ G H
Sbjct: 143 ITCGDYHSLALSKGGELFAWGQNLHGQLGVGRKFPSTTTPQIVEHLAGVPLAQISAGEAH 202
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
S+AL+ SG++YSWG N GQ GL + K I L + + CG +H+ +L++
Sbjct: 203 SMALSMSGNIYSWGKNECGQLGLG-HTESKDDPSLIEGLDNQKVEFVACGGSHSALLTQD 261
Query: 620 RCGFWMG 640
F G
Sbjct: 262 GLLFTFG 268
Score = 78.2 bits (184), Expect = 3e-14
Identities = 45/117 (38%), Positives = 63/117 (53%), Gaps = 3/117 (2%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLG-AHAQDKPKFVKGLATKNVIQVACGAY 436
I+ G HS+A+ G +SWG + GQLG LG ++D P ++GL + V VACG
Sbjct: 196 ISAGEAHSMALSMSGNIYSWGKNECGQLG--LGHTESKDDPSLIEGLDNQKVEFVACGGS 253
Query: 437 HSVALTNSGDLYSWGANSYGQCGLELYQT--RKCHLQHISSLIGVPIALITCGNNHT 601
HS LT G L+++GA +GQ G Q R C ++ L+G + I CG HT
Sbjct: 254 HSALLTQDGLLFTFGAGKHGQLGHNSTQNELRPC---LVAELVGYRVTQIACGRWHT 307
Score = 73.3 bits (172), Expect = 7e-13
Identities = 41/117 (35%), Positives = 60/117 (51%)
Frame = +2
Query: 269 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 448
G +H L + G+PF + + SM L +F L K +IQ+ CG YHS+A
Sbjct: 105 GAEHMLILSSDGKPFEYDNYSMKHL------------RFESILQEKKIIQITCGDYHSLA 152
Query: 449 LTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
L+ G+L++WG N +GQ G+ Q + L GVP+A I+ G H+ LS S
Sbjct: 153 LSKGGELFAWGQNLHGQLGVGRKFPSTTTPQIVEHLAGVPLAQISAGEAHSMALSMS 209
Score = 56.0 bits (129), Expect = 1e-07
Identities = 29/83 (34%), Positives = 49/83 (59%), Gaps = 1/83 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG HS + + G F++G+ GQLG+N + +P V L V Q+ACG +H
Sbjct: 248 VACGGSHSALLTQDGLLFTFGAGKHGQLGHN-STQNELRPCLVAELVGYRVTQIACGRWH 306
Query: 440 SVA-LTNSGDLYSWGANSYGQCG 505
++A +++ G ++S+G+ GQ G
Sbjct: 307 TLAYVSDLGKVFSFGSGKDGQLG 329
Score = 44.4 bits (100), Expect = 4e-04
Identities = 23/45 (51%), Positives = 33/45 (73%), Gaps = 1/45 (2%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLG-RQTESDNGKNPALVE 233
++AGE HS+ LS SG++YS G N+ GQLG TES + +P+L+E
Sbjct: 196 ISAGEAHSMALSMSGNIYSWGKNECGQLGLGHTESKD--DPSLIE 238
Score = 37.9 bits (84), Expect = 0.034
Identities = 23/47 (48%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
Frame = +2
Query: 254 TTIACGLQHSLA-IDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVK 391
T IACG H+LA + + G+ FS+GS GQLGN G Q P VK
Sbjct: 298 TQIACGRWHTLAYVSDLGKVFSFGSGKDGQLGNG-GTRDQLMPLPVK 343
Score = 36.7 bits (81), Expect = 0.078
Identities = 17/44 (38%), Positives = 25/44 (56%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 233
+ G++HSL LS G L++ G N GQLG + + P +VE
Sbjct: 143 ITCGDYHSLALSKGGELFAWGQNLHGQLGVGRKFPSTTTPQIVE 186
Score = 34.3 bits (75), Expect = 0.42
Identities = 19/57 (33%), Positives = 30/57 (52%)
Frame = +3
Query: 60 PTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALV 230
P+L + ++ ++ VA G HS L+ G L++ G GQLG + + N P LV
Sbjct: 234 PSLIEGLDNQKVEFVACGGSHSALLTQDGLLFTFGAGKHGQLGHNS-TQNELRPCLV 289
Score = 31.1 bits (67), Expect = 3.9
Identities = 17/54 (31%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
Frame = +3
Query: 30 GSQITDLVIKPTLSKWKESDHIQAVAAGEFHSL-YLSNSGHLYSCGNNDVGQLG 188
G T ++P L + +A G +H+L Y+S+ G ++S G+ GQLG
Sbjct: 276 GHNSTQNELRPCLVAELVGYRVTQIACGRWHTLAYVSDLGKVFSFGSGKDGQLG 329
>AY337518-1|AAR00320.1| 1024|Homo sapiens HECT E3 ubiquitin ligase
protein.
Length = 1024
Score = 83.8 bits (198), Expect = 5e-16
Identities = 45/127 (35%), Positives = 67/127 (52%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
I CG HSLA+ + G+ F+WG + GQLG + P+ V+ LA + Q++ G H
Sbjct: 143 ITCGDYHSLALSKGGELFAWGQNLHGQLGVGRKFPSTTTPQIVEHLAGVPLAQISAGEAH 202
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
S AL+ SG++YSWG N GQ GL + K I L + + CG +H+ +L++
Sbjct: 203 STALSMSGNIYSWGKNECGQLGLG-HTESKDDPSLIEGLDNQKVEFVACGGSHSALLTQD 261
Query: 620 RCGFWMG 640
F G
Sbjct: 262 GLLFTFG 268
Score = 77.0 bits (181), Expect = 6e-14
Identities = 45/117 (38%), Positives = 62/117 (52%), Gaps = 3/117 (2%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLG-AHAQDKPKFVKGLATKNVIQVACGAY 436
I+ G HS A+ G +SWG + GQLG LG ++D P ++GL + V VACG
Sbjct: 196 ISAGEAHSTALSMSGNIYSWGKNECGQLG--LGHTESKDDPSLIEGLDNQKVEFVACGGS 253
Query: 437 HSVALTNSGDLYSWGANSYGQCGLELYQT--RKCHLQHISSLIGVPIALITCGNNHT 601
HS LT G L+++GA +GQ G Q R C ++ L+G + I CG HT
Sbjct: 254 HSALLTQDGLLFTFGAGKHGQLGHNSTQNELRPC---LVAELVGYRVTQIACGRWHT 307
Score = 72.5 bits (170), Expect = 1e-12
Identities = 41/117 (35%), Positives = 60/117 (51%)
Frame = +2
Query: 269 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 448
G +H L + G+PF + + SM L +F L K +IQ+ CG YHS+A
Sbjct: 105 GAEHMLILSSDGKPFEYDNYSMKHL------------RFESILQEKKIIQITCGDYHSLA 152
Query: 449 LTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
L+ G+L++WG N +GQ G+ Q + L GVP+A I+ G H+ LS S
Sbjct: 153 LSKGGELFAWGQNLHGQLGVGRKFPSTTTPQIVEHLAGVPLAQISAGEAHSTALSMS 209
Score = 56.0 bits (129), Expect = 1e-07
Identities = 29/83 (34%), Positives = 49/83 (59%), Gaps = 1/83 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG HS + + G F++G+ GQLG+N + +P V L V Q+ACG +H
Sbjct: 248 VACGGSHSALLTQDGLLFTFGAGKHGQLGHN-STQNELRPCLVAELVGYRVTQIACGRWH 306
Query: 440 SVA-LTNSGDLYSWGANSYGQCG 505
++A +++ G ++S+G+ GQ G
Sbjct: 307 TLAYVSDLGKVFSFGSGKDGQLG 329
Score = 43.2 bits (97), Expect = 9e-04
Identities = 23/45 (51%), Positives = 32/45 (71%), Gaps = 1/45 (2%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLG-RQTESDNGKNPALVE 233
++AGE HS LS SG++YS G N+ GQLG TES + +P+L+E
Sbjct: 196 ISAGEAHSTALSMSGNIYSWGKNECGQLGLGHTESKD--DPSLIE 238
Score = 37.9 bits (84), Expect = 0.034
Identities = 23/47 (48%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
Frame = +2
Query: 254 TTIACGLQHSLA-IDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVK 391
T IACG H+LA + + G+ FS+GS GQLGN G Q P VK
Sbjct: 298 TQIACGRWHTLAYVSDLGKVFSFGSGKDGQLGNG-GTRDQLMPLPVK 343
Score = 36.7 bits (81), Expect = 0.078
Identities = 17/44 (38%), Positives = 25/44 (56%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 233
+ G++HSL LS G L++ G N GQLG + + P +VE
Sbjct: 143 ITCGDYHSLALSKGGELFAWGQNLHGQLGVGRKFPSTTTPQIVE 186
Score = 34.3 bits (75), Expect = 0.42
Identities = 19/57 (33%), Positives = 30/57 (52%)
Frame = +3
Query: 60 PTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALV 230
P+L + ++ ++ VA G HS L+ G L++ G GQLG + + N P LV
Sbjct: 234 PSLIEGLDNQKVEFVACGGSHSALLTQDGLLFTFGAGKHGQLGHNS-TQNELRPCLV 289
Score = 31.1 bits (67), Expect = 3.9
Identities = 17/54 (31%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
Frame = +3
Query: 30 GSQITDLVIKPTLSKWKESDHIQAVAAGEFHSL-YLSNSGHLYSCGNNDVGQLG 188
G T ++P L + +A G +H+L Y+S+ G ++S G+ GQLG
Sbjct: 276 GHNSTQNELRPCLVAELVGYRVTQIACGRWHTLAYVSDLGKVFSFGSGKDGQLG 329
>AF071172-1|AAD08657.1| 4834|Homo sapiens HERC2 protein.
Length = 4834
Score = 82.6 bits (195), Expect = 1e-15
Identities = 44/115 (38%), Positives = 66/115 (57%), Gaps = 1/115 (0%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
I CG Q SLA+ + G ++WG +LG+ H + KP+ V+GL K ++ VA GA H
Sbjct: 3210 IECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVR-KPQVVEGLRGKKIVHVAVGALH 3268
Query: 440 SVALTNSGDLYSWGANSYGQCGL-ELYQTRKCHLQHISSLIGVPIALITCGNNHT 601
+A+T+SG +Y+WG N +GQ G RK L + L G I + CG++H+
Sbjct: 3269 CLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTL--VQGLEGQKITRVACGSSHS 3321
Score = 80.6 bits (190), Expect = 5e-15
Identities = 40/115 (34%), Positives = 65/115 (56%)
Frame = +2
Query: 269 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 448
G +H+ A+ G+ FSWG G+LG+ + DKP+ ++ L TK + +ACG+ HS A
Sbjct: 3055 GGRHATALTVDGKVFSWGEGDDGKLGHFSRMNC-DKPRLIEALKTKRIRDIACGSSHSAA 3113
Query: 449 LTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
LT+SG+LY+WG YG+ G T + + + L+G + + CG+ L+
Sbjct: 3114 LTSSGELYTWGLGEYGRLG-HGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLA 3167
Score = 78.6 bits (185), Expect = 2e-14
Identities = 47/123 (38%), Positives = 68/123 (55%), Gaps = 3/123 (2%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGA-- 433
IACG HS A+ G+ ++WG G+LG+ Q KPK VK L VIQVACG+
Sbjct: 3104 IACGSSHSAALTSSGELYTWGLGEYGRLGHGDNT-TQLKPKMVKVLLGHRVIQVACGSRD 3162
Query: 434 YHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHL-QHISSLIGVPIALITCGNNHTFVL 610
++ALT+ G ++SWG +G+ G + C++ Q+I L G + I CG + L
Sbjct: 3163 AQTLALTDEGLVFSWGDGDFGKLGRG--GSEGCNIPQNIERLNGQGVCQIECGAQFSLAL 3220
Query: 611 SKS 619
+KS
Sbjct: 3221 TKS 3223
Score = 77.0 bits (181), Expect = 6e-14
Identities = 39/121 (32%), Positives = 65/121 (53%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ CG Q S+A+ + G ++WG +LG+ H + +P+ V+GL K VI +A G+ H
Sbjct: 4202 VECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVR-RPRQVQGLQGKKVIAIATGSLH 4260
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
V T G++Y+WG N GQ G + + +++L G + + CG+ HT S S
Sbjct: 4261 CVCCTEDGEVYTWGDNDEGQLGDGTTNAIQ-RPRLVAALQGKKVNRVACGSAHTLAWSTS 4319
Query: 620 R 622
+
Sbjct: 4320 K 4320
Score = 71.7 bits (168), Expect = 2e-12
Identities = 42/125 (33%), Positives = 62/125 (49%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ CG Q S+A+ + GQ +SWG +LG+ H + PK ++GL K VI VA G+ H
Sbjct: 662 VRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVR-YPKLLEGLQGKKVIDVAAGSTH 720
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
+ALT +++SWG+N Q + + K + L I I CG +F S
Sbjct: 721 CLALTEDSEVHSWGSNDQCQ-HFDTLRVTKPEPAALPGLDTKHIVGIACGPAQSFAWSS- 778
Query: 620 RCGFW 634
C W
Sbjct: 779 -CSEW 782
Score = 70.9 bits (166), Expect = 4e-12
Identities = 44/135 (32%), Positives = 69/135 (51%), Gaps = 2/135 (1%)
Frame = +2
Query: 218 SSFSGNI*RLHNTTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGL 397
S+FSG H IACG +S AI G+ ++WG + G+LG+ + + P V GL
Sbjct: 542 SAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHG-SSEDEAIPMLVAGL 600
Query: 398 ATKNVIQVACGA--YHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPI 571
VI VACG+ ++A+T +G ++SWG YG+ G K + I L + +
Sbjct: 601 KGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTP-KLIEKLQDLDV 659
Query: 572 ALITCGNNHTFVLSK 616
+ CG+ + L+K
Sbjct: 660 VKVRCGSQFSIALTK 674
Score = 68.9 bits (161), Expect = 2e-11
Identities = 39/129 (30%), Positives = 66/129 (51%), Gaps = 2/129 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGA-- 433
+A G HS + G ++WG G+LG++ + Q KPK V+ L V+ +ACG+
Sbjct: 4096 VAAGGAHSACVTAAGDLYTWGKGRYGRLGHS-DSEDQLKPKLVEALQGHRVVDIACGSGD 4154
Query: 434 YHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
++ LT+ ++SWG YG+ G K ++ I SL G+ + + CG+ + L+
Sbjct: 4155 AQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMK-IDSLTGLGVVKVECGSQFSVALT 4213
Query: 614 KSRCGFWMG 640
KS + G
Sbjct: 4214 KSGAVYTWG 4222
Score = 66.9 bits (156), Expect = 6e-11
Identities = 30/87 (34%), Positives = 48/87 (55%)
Frame = +2
Query: 245 LHNTTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVA 424
+ + G +H LA+ G+ +SWG G+LG+ + D+P+ ++ L V+ VA
Sbjct: 4039 IKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPC-DRPRVIESLRGIEVVDVA 4097
Query: 425 CGAYHSVALTNSGDLYSWGANSYGQCG 505
G HS +T +GDLY+WG YG+ G
Sbjct: 4098 AGGAHSACVTAAGDLYTWGKGRYGRLG 4124
Score = 66.1 bits (154), Expect = 1e-10
Identities = 37/121 (30%), Positives = 62/121 (51%), Gaps = 2/121 (1%)
Frame = +2
Query: 260 IACGL--QHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGA 433
+ACG +LA+ E GQ +SWG G+LG G+ PK ++ L +V++V CG+
Sbjct: 608 VACGSGDAQTLAVTENGQVWSWGDGDYGKLGRG-GSDGCKTPKLIEKLQDLDVVKVRCGS 666
Query: 434 YHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
S+ALT G +YSWG + G + + + + + L G + + G+ H L+
Sbjct: 667 QFSIALTKDGQVYSWGKGDNQRLGHGTEEHVR-YPKLLEGLQGKKVIDVAAGSTHCLALT 725
Query: 614 K 616
+
Sbjct: 726 E 726
Score = 64.9 bits (151), Expect = 3e-10
Identities = 35/121 (28%), Positives = 63/121 (52%), Gaps = 4/121 (3%)
Frame = +2
Query: 278 HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGL----ATKNVIQVACGAYHSV 445
H LA+ G+ +SWG G+LG+ ++PK + A K+V+ +ACG+ +S
Sbjct: 506 HYLALAATGEVYSWGCGDGGRLGHG-DTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSA 564
Query: 446 ALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKSRC 625
A+T G+LY+WG +YG+ G + + ++ L G+ + + CG+ L+ +
Sbjct: 565 AITAEGELYTWGRGNYGRLGHGSSEDEAIPML-VAGLKGLKVIDVACGSGDAQTLAVTEN 623
Query: 626 G 628
G
Sbjct: 624 G 624
Score = 61.7 bits (143), Expect = 2e-09
Identities = 31/84 (36%), Positives = 49/84 (58%), Gaps = 2/84 (2%)
Frame = +2
Query: 260 IACGLQ--HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGA 433
+ACG + +LA+ + G FSWG G+LG G+ + P+ ++ L + V Q+ CGA
Sbjct: 3156 VACGSRDAQTLALTDEGLVFSWGDGDFGKLGRG-GSEGCNIPQNIERLNGQGVCQIECGA 3214
Query: 434 YHSVALTNSGDLYSWGANSYGQCG 505
S+ALT SG +++WG Y + G
Sbjct: 3215 QFSLALTKSGVVWTWGKGDYFRLG 3238
Score = 56.8 bits (131), Expect = 7e-08
Identities = 27/65 (41%), Positives = 38/65 (58%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+A G H LA+ + GQ ++WG + GQ GN KP V+GL + + +VACG+ H
Sbjct: 3262 VAVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTT-VNRKPTLVQGLEGQKITRVACGSSH 3320
Query: 440 SVALT 454
SVA T
Sbjct: 3321 SVAWT 3325
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Frame = +2
Query: 260 IACGL--QHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGA 433
IACG +L + + +SWG G+LG G+ P + L V++V CG+
Sbjct: 4148 IACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRG-GSDGCKVPMKIDSLTGLGVVKVECGS 4206
Query: 434 YHSVALTNSGDLYSWGANSYGQCG 505
SVALT SG +Y+WG Y + G
Sbjct: 4207 QFSVALTKSGAVYTWGKGDYHRLG 4230
Score = 52.0 bits (119), Expect = 2e-06
Identities = 39/139 (28%), Positives = 66/139 (47%), Gaps = 3/139 (2%)
Frame = +2
Query: 212 KESSFSGNI*RLHNTTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVK 391
K SFS + L+ +A G + A+ G+ ++ G + G+LG + + P+ +
Sbjct: 2981 KVPSFSETLSALNVVQVAGGSKSLFAVTVEGKVYACGEATNGRLGLGISSGTVPIPRQIT 3040
Query: 392 GLATKNVIQVAC--GAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQH-ISSLIG 562
L++ V +VA G H+ ALT G ++SWG G+ G + C I +L
Sbjct: 3041 ALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLG--HFSRMNCDKPRLIEALKT 3098
Query: 563 VPIALITCGNNHTFVLSKS 619
I I CG++H+ L+ S
Sbjct: 3099 KRIRDIACGSSHSAALTSS 3117
Score = 43.6 bits (98), Expect = 7e-04
Identities = 17/45 (37%), Positives = 32/45 (71%), Gaps = 2/45 (4%)
Frame = +2
Query: 377 PKFVKGLATKNVIQVACGA--YHSVALTNSGDLYSWGANSYGQCG 505
P+ V+GLA++N++++A + +H +AL +G++YSWG G+ G
Sbjct: 484 PQLVQGLASRNIVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLG 528
Score = 43.2 bits (97), Expect = 9e-04
Identities = 28/82 (34%), Positives = 43/82 (52%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 442
A GL+ + I + F WG + QLG G+ + P F + L+ NV+QVA G+
Sbjct: 2948 AAGLESAATIRT--KVFVWGLNDKDQLGGLKGSKIK-VPSFSETLSALNVVQVAGGSKSL 3004
Query: 443 VALTNSGDLYSWGANSYGQCGL 508
A+T G +Y+ G + G+ GL
Sbjct: 3005 FAVTVEGKVYACGEATNGRLGL 3026
Score = 38.7 bits (86), Expect = 0.019
Identities = 23/69 (33%), Positives = 34/69 (49%)
Frame = +2
Query: 302 GQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWG 481
G + WG + GQLG GA + P + LAT +Q+ G A+T G LY+ G
Sbjct: 3952 GTIYGWGHNHRGQLGGIEGAKVK-VPTPCEALATLRPVQLIGGEQTLFAVTADGKLYATG 4010
Query: 482 ANSYGQCGL 508
+ G+ G+
Sbjct: 4011 YGAGGRLGI 4019
Score = 36.3 bits (80), Expect = 0.10
Identities = 17/51 (33%), Positives = 27/51 (52%)
Frame = +3
Query: 45 DLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQT 197
D V +P + + + A+A G H + + G +Y+ G+ND GQLG T
Sbjct: 4235 DHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGT 4285
Score = 33.9 bits (74), Expect = 0.55
Identities = 18/47 (38%), Positives = 28/47 (59%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFK 242
VAAG HS ++ +G LY+ G G+LG ++S++ P LVE +
Sbjct: 4096 VAAGGAHSACVTAAGDLYTWGKGRYGRLG-HSDSEDQLKPKLVEALQ 4141
>BC038104-1|AAH38104.1| 355|Homo sapiens RCBTB1 protein protein.
Length = 355
Score = 80.2 bits (189), Expect = 6e-15
Identities = 40/118 (33%), Positives = 66/118 (55%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG HS+A+ G+ F+WG ++ GQ+G+ A+ K L K V+ +ACG
Sbjct: 133 VACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTS 192
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
S+A+ ++G++Y WG N GQ GL + ++ +++L V + I CG HT L+
Sbjct: 193 SMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVR-VAALHSVCVNQIVCGYAHTLALT 249
Score = 71.3 bits (167), Expect = 3e-12
Identities = 38/83 (45%), Positives = 52/83 (62%), Gaps = 1/83 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHA-QDKPKFVKGLATKNVIQVACGAY 436
IACG S+A+ + G+ + WG + GQLG LG + Q P V L + V Q+ CG
Sbjct: 186 IACGQTSSMAVLDNGEVYGWGYNGNGQLG--LGNNGNQLTPVRVAALHSVCVNQIVCGYA 243
Query: 437 HSVALTNSGDLYSWGANSYGQCG 505
H++ALT+ G LY+WGAN+YGQ G
Sbjct: 244 HTLALTDEGLLYAWGANTYGQLG 266
Score = 62.5 bits (145), Expect = 1e-09
Identities = 28/76 (36%), Positives = 42/76 (55%)
Frame = +2
Query: 278 HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTN 457
H L E G ++WG + QLGN + L K V++VACG++HS+AL
Sbjct: 86 HVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIATVQVCTNLLIKQVVEVACGSHHSMALAA 145
Query: 458 SGDLYSWGANSYGQCG 505
G++++WG N+ GQ G
Sbjct: 146 DGEVFAWGYNNCGQVG 161
Score = 31.5 bits (68), Expect = 2.9
Identities = 17/51 (33%), Positives = 28/51 (54%)
Frame = +3
Query: 93 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKD 245
+ + G H+L L++ G LY+ G N GQLG + +N +PA + K+
Sbjct: 235 VNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGNK-NNLLSPAHIMVEKE 284
Score = 30.3 bits (65), Expect = 6.8
Identities = 12/29 (41%), Positives = 19/29 (65%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLG 188
VA G HS+ L+ G +++ G N+ GQ+G
Sbjct: 133 VACGSHHSMALAADGEVFAWGYNNCGQVG 161
>AL139321-5|CAH71047.1| 531|Homo sapiens regulator of chromosome
condensation (RCC1) and BTB (POZ) domain containing pro
protein.
Length = 531
Score = 80.2 bits (189), Expect = 6e-15
Identities = 40/118 (33%), Positives = 66/118 (55%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG HS+A+ G+ F+WG ++ GQ+G+ A+ K L K V+ +ACG
Sbjct: 133 VACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTS 192
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
S+A+ ++G++Y WG N GQ GL + ++ +++L V + I CG HT L+
Sbjct: 193 SMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVR-VAALHSVCVNQIVCGYAHTLALT 249
Score = 71.3 bits (167), Expect = 3e-12
Identities = 38/83 (45%), Positives = 52/83 (62%), Gaps = 1/83 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHA-QDKPKFVKGLATKNVIQVACGAY 436
IACG S+A+ + G+ + WG + GQLG LG + Q P V L + V Q+ CG
Sbjct: 186 IACGQTSSMAVLDNGEVYGWGYNGNGQLG--LGNNGNQLTPVRVAALHSVCVNQIVCGYA 243
Query: 437 HSVALTNSGDLYSWGANSYGQCG 505
H++ALT+ G LY+WGAN+YGQ G
Sbjct: 244 HTLALTDEGLLYAWGANTYGQLG 266
Score = 62.5 bits (145), Expect = 1e-09
Identities = 28/76 (36%), Positives = 42/76 (55%)
Frame = +2
Query: 278 HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTN 457
H L E G ++WG + QLGN + L K V++VACG++HS+AL
Sbjct: 86 HVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAA 145
Query: 458 SGDLYSWGANSYGQCG 505
G++++WG N+ GQ G
Sbjct: 146 DGEVFAWGYNNCGQVG 161
Score = 31.5 bits (68), Expect = 2.9
Identities = 17/51 (33%), Positives = 28/51 (54%)
Frame = +3
Query: 93 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKD 245
+ + G H+L L++ G LY+ G N GQLG + +N +PA + K+
Sbjct: 235 VNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGNK-NNLLSPAHIMVEKE 284
Score = 30.3 bits (65), Expect = 6.8
Identities = 12/29 (41%), Positives = 19/29 (65%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLG 188
VA G HS+ L+ G +++ G N+ GQ+G
Sbjct: 133 VACGSHHSMALAADGEVFAWGYNNCGQVG 161
>AK096654-1|BAC04833.1| 531|Homo sapiens protein ( Homo sapiens
cDNA FLJ39335 fis, clone OCBBF2017398, moderately
similar to Homo sapiens RCC1-like G exchanging factor
RLG mRNA. ).
Length = 531
Score = 80.2 bits (189), Expect = 6e-15
Identities = 40/118 (33%), Positives = 66/118 (55%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG HS+A+ G+ F+WG ++ GQ+G+ A+ K L K V+ +ACG
Sbjct: 133 VACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTS 192
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
S+A+ ++G++Y WG N GQ GL + ++ +++L V + I CG HT L+
Sbjct: 193 SMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVR-VAALHSVCVNQIVCGYAHTLALT 249
Score = 71.3 bits (167), Expect = 3e-12
Identities = 38/83 (45%), Positives = 52/83 (62%), Gaps = 1/83 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHA-QDKPKFVKGLATKNVIQVACGAY 436
IACG S+A+ + G+ + WG + GQLG LG + Q P V L + V Q+ CG
Sbjct: 186 IACGQTSSMAVLDNGEVYGWGYNGNGQLG--LGNNGNQLTPVRVAALHSVCVNQIVCGYA 243
Query: 437 HSVALTNSGDLYSWGANSYGQCG 505
H++ALT+ G LY+WGAN+YGQ G
Sbjct: 244 HTLALTDEGLLYAWGANTYGQLG 266
Score = 62.5 bits (145), Expect = 1e-09
Identities = 28/76 (36%), Positives = 42/76 (55%)
Frame = +2
Query: 278 HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTN 457
H L E G ++WG + QLGN + L K V++VACG++HS+AL
Sbjct: 86 HVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAA 145
Query: 458 SGDLYSWGANSYGQCG 505
G++++WG N+ GQ G
Sbjct: 146 DGEVFAWGYNNCGQVG 161
Score = 31.5 bits (68), Expect = 2.9
Identities = 17/51 (33%), Positives = 28/51 (54%)
Frame = +3
Query: 93 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKD 245
+ + G H+L L++ G LY+ G N GQLG + +N +PA + K+
Sbjct: 235 VNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGNK-NNLLSPAHIMVEKE 284
Score = 30.3 bits (65), Expect = 6.8
Identities = 12/29 (41%), Positives = 19/29 (65%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLG 188
VA G HS+ L+ G +++ G N+ GQ+G
Sbjct: 133 VACGSHHSMALAADGEVFAWGYNNCGQVG 161
>AJ319660-1|CAC40027.1| 531|Homo sapiens guanine nucleotide
exchange factor protein.
Length = 531
Score = 80.2 bits (189), Expect = 6e-15
Identities = 40/118 (33%), Positives = 66/118 (55%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG HS+A+ G+ F+WG ++ GQ+G+ A+ K L K V+ +ACG
Sbjct: 133 VACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTS 192
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
S+A+ ++G++Y WG N GQ GL + ++ +++L V + I CG HT L+
Sbjct: 193 SMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVR-VAALHSVCVNQIVCGYAHTLALT 249
Score = 71.3 bits (167), Expect = 3e-12
Identities = 38/83 (45%), Positives = 52/83 (62%), Gaps = 1/83 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHA-QDKPKFVKGLATKNVIQVACGAY 436
IACG S+A+ + G+ + WG + GQLG LG + Q P V L + V Q+ CG
Sbjct: 186 IACGQTSSMAVLDNGEVYGWGYNGNGQLG--LGNNGNQLTPVRVAALHSVCVNQIVCGYA 243
Query: 437 HSVALTNSGDLYSWGANSYGQCG 505
H++ALT+ G LY+WGAN+YGQ G
Sbjct: 244 HTLALTDEGLLYAWGANTYGQLG 266
Score = 62.5 bits (145), Expect = 1e-09
Identities = 28/76 (36%), Positives = 42/76 (55%)
Frame = +2
Query: 278 HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTN 457
H L E G ++WG + QLGN + L K V++VACG++HS+AL
Sbjct: 86 HVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAA 145
Query: 458 SGDLYSWGANSYGQCG 505
G++++WG N+ GQ G
Sbjct: 146 DGEVFAWGYNNCGQVG 161
Score = 31.5 bits (68), Expect = 2.9
Identities = 17/51 (33%), Positives = 28/51 (54%)
Frame = +3
Query: 93 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKD 245
+ + G H+L L++ G LY+ G N GQLG + +N +PA + K+
Sbjct: 235 VNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGNK-NNLLSPAHIMVEKE 284
Score = 30.3 bits (65), Expect = 6.8
Identities = 12/29 (41%), Positives = 19/29 (65%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLG 188
VA G HS+ L+ G +++ G N+ GQ+G
Sbjct: 133 VACGSHHSMALAADGEVFAWGYNNCGQVG 161
>AF334406-1|AAK38372.1| 531|Homo sapiens CLLL7 protein protein.
Length = 531
Score = 80.2 bits (189), Expect = 6e-15
Identities = 40/118 (33%), Positives = 66/118 (55%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG HS+A+ G+ F+WG ++ GQ+G+ A+ K L K V+ +ACG
Sbjct: 133 VACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTS 192
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
S+A+ ++G++Y WG N GQ GL + ++ +++L V + I CG HT L+
Sbjct: 193 SMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVR-VAALHSVCVNQIVCGYAHTLALT 249
Score = 71.3 bits (167), Expect = 3e-12
Identities = 38/83 (45%), Positives = 52/83 (62%), Gaps = 1/83 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHA-QDKPKFVKGLATKNVIQVACGAY 436
IACG S+A+ + G+ + WG + GQLG LG + Q P V L + V Q+ CG
Sbjct: 186 IACGQTSSMAVLDNGEVYGWGYNGNGQLG--LGNNGNQLTPVRVAALHSVCVNQIVCGYA 243
Query: 437 HSVALTNSGDLYSWGANSYGQCG 505
H++ALT+ G LY+WGAN+YGQ G
Sbjct: 244 HTLALTDEGLLYAWGANTYGQLG 266
Score = 62.5 bits (145), Expect = 1e-09
Identities = 28/76 (36%), Positives = 42/76 (55%)
Frame = +2
Query: 278 HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTN 457
H L E G ++WG + QLGN + L K V++VACG++HS+AL
Sbjct: 86 HVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAA 145
Query: 458 SGDLYSWGANSYGQCG 505
G++++WG N+ GQ G
Sbjct: 146 DGEVFAWGYNNCGQVG 161
Score = 31.5 bits (68), Expect = 2.9
Identities = 17/51 (33%), Positives = 28/51 (54%)
Frame = +3
Query: 93 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKD 245
+ + G H+L L++ G LY+ G N GQLG + +N +PA + K+
Sbjct: 235 VNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGNK-NNLLSPAHIMVEKE 284
Score = 30.3 bits (65), Expect = 6.8
Identities = 12/29 (41%), Positives = 19/29 (65%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLG 188
VA G HS+ L+ G +++ G N+ GQ+G
Sbjct: 133 VACGSHHSMALAADGEVFAWGYNNCGQVG 161
>AK092403-1|BAC03879.1| 184|Homo sapiens protein ( Homo sapiens
cDNA FLJ35084 fis, clone PLACE6005482. ).
Length = 184
Score = 79.8 bits (188), Expect = 8e-15
Identities = 46/129 (35%), Positives = 67/129 (51%), Gaps = 2/129 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
++CG HSLA+ + Q FSWG +S GQLG +Q P+ V+ L + QVA G H
Sbjct: 11 VSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAH 70
Query: 440 SVALTNSGDLYSWGANSYGQCGL--ELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
S AL+ G + WG+NS GQ L + + +L + + I+CG+ HT VL+
Sbjct: 71 SFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVYISCGDAHTAVLT 130
Query: 614 KSRCGFWMG 640
+ F G
Sbjct: 131 QDGKVFTFG 139
Score = 70.9 bits (166), Expect = 4e-12
Identities = 32/77 (41%), Positives = 45/77 (58%)
Frame = +2
Query: 410 VIQVACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCG 589
+IQV+CG YHS+AL+ ++SWG NS+GQ GL + Q + SL G+P+A + G
Sbjct: 8 IIQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAG 67
Query: 590 NNHTFVLSKSRCGFWMG 640
H+F LS F G
Sbjct: 68 GAHSFALSLCGTSFGWG 84
Score = 63.3 bits (147), Expect = 8e-10
Identities = 39/115 (33%), Positives = 58/115 (50%), Gaps = 3/115 (2%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQL---GNNLGAHAQDKPKFVKGLATKNVIQVACG 430
+A G HS A+ G F WGS+S GQL G N+ + +KP V L V+ ++CG
Sbjct: 64 VAAGGAHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQS-NKPLSVGALKNLGVVYISCG 122
Query: 431 AYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNN 595
H+ LT G ++++G N GQ G K Q + + G+ ++ I CG N
Sbjct: 123 DAHTAVLTQDGKVFTFGDNRSGQLGYS-PTPEKRGPQLVERIDGL-VSQIDCGRN 175
Score = 36.7 bits (81), Expect = 0.078
Identities = 18/53 (33%), Positives = 27/53 (50%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIRQ 260
V+ G +HSL LS ++S G N GQLG E + +P V + + + Q
Sbjct: 11 VSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQ 63
Score = 31.1 bits (67), Expect = 3.9
Identities = 14/44 (31%), Positives = 26/44 (59%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 233
++ G+ H+ L+ G +++ G+N GQLG + + + P LVE
Sbjct: 119 ISCGDAHTAVLTQDGKVFTFGDNRSGQLG-YSPTPEKRGPQLVE 161
>BC029052-1|AAH29052.1| 551|Homo sapiens regulator of chromosome
condensation (RCC1) and BTB (POZ) domain containing pro
protein.
Length = 551
Score = 78.6 bits (185), Expect = 2e-14
Identities = 43/121 (35%), Positives = 68/121 (56%), Gaps = 3/121 (2%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG-LATKNVIQVACGAY 436
+ACG HSL + G+ F+WG ++ GQ+G+ + Q P+ V G L K V+ +ACG
Sbjct: 157 VACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVN-QPIPRRVTGCLQNKVVVTIACGQM 215
Query: 437 HSVALTNSGDLYSWGANSYGQCGL--ELYQTRKCHLQHISSLIGVPIALITCGNNHTFVL 610
+A+ ++G++Y WG N GQ GL Q C +++L G+ + + CG HT VL
Sbjct: 216 CCMAVVDTGEVYVWGYNGNGQLGLGNSGNQPTPC---RVAALQGIRVQRVACGYAHTLVL 272
Query: 611 S 613
+
Sbjct: 273 T 273
Score = 72.1 bits (169), Expect = 2e-12
Identities = 36/83 (43%), Positives = 49/83 (59%)
Frame = +2
Query: 257 TIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAY 436
TIACG +A+ + G+ + WG + GQLG + Q P V L V +VACG
Sbjct: 209 TIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGN-QPTPCRVAALQGIRVQRVACGYA 267
Query: 437 HSVALTNSGDLYSWGANSYGQCG 505
H++ LT+ G +Y+WGANSYGQ G
Sbjct: 268 HTLVLTDEGQVYAWGANSYGQLG 290
Score = 70.1 bits (164), Expect = 7e-12
Identities = 29/68 (42%), Positives = 43/68 (63%)
Frame = +2
Query: 302 GQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWG 481
G+ F+WG ++ QLGN H L+ K VI+VACG+YHS+ LT+ G++++WG
Sbjct: 118 GEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWG 177
Query: 482 ANSYGQCG 505
N+ GQ G
Sbjct: 178 YNNSGQVG 185
Score = 40.7 bits (91), Expect = 0.005
Identities = 29/105 (27%), Positives = 53/105 (50%), Gaps = 4/105 (3%)
Frame = +2
Query: 311 FSWGSDSMGQLGNNLG-AHAQDKPKFVKGLATKNVIQVACGAY-HSVALTNSGDLYSWGA 484
F G++ G LG LG + +P+ + L K + ++ G+ H V T G++++WG
Sbjct: 68 FVLGTNCCGCLG--LGDVQSTIEPRRLDSLNGKKIACLSYGSGPHIVLATTEGEVFTWGH 125
Query: 485 NSYGQC--GLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
N+Y Q G + CH+ ++L + + CG+ H+ VL+
Sbjct: 126 NAYSQLGNGTTNHGLVPCHIS--TNLSNKQVIEVACGSYHSLVLT 168
Score = 38.7 bits (86), Expect = 0.019
Identities = 21/51 (41%), Positives = 28/51 (54%)
Frame = +3
Query: 93 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKD 245
+Q VA G H+L L++ G +Y+ G N GQLG +S N P V KD
Sbjct: 259 VQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGNKS-NQSYPTPVTVEKD 308
Score = 33.9 bits (74), Expect = 0.55
Identities = 13/29 (44%), Positives = 21/29 (72%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLG 188
VA G +HSL L++ G +++ G N+ GQ+G
Sbjct: 157 VACGSYHSLVLTSDGEVFAWGYNNSGQVG 185
>AY341245-1|AAP88928.1| 551|Homo sapiens chromosome condensation
1-like protein.
Length = 551
Score = 78.6 bits (185), Expect = 2e-14
Identities = 43/121 (35%), Positives = 68/121 (56%), Gaps = 3/121 (2%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG-LATKNVIQVACGAY 436
+ACG HSL + G+ F+WG ++ GQ+G+ + Q P+ V G L K V+ +ACG
Sbjct: 157 VACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVN-QPIPRRVTGCLQNKVVVTIACGQM 215
Query: 437 HSVALTNSGDLYSWGANSYGQCGL--ELYQTRKCHLQHISSLIGVPIALITCGNNHTFVL 610
+A+ ++G++Y WG N GQ GL Q C +++L G+ + + CG HT VL
Sbjct: 216 CCMAVVDTGEVYVWGYNGNGQLGLGNSGNQPTPC---RVAALQGIRVQRVACGYAHTLVL 272
Query: 611 S 613
+
Sbjct: 273 T 273
Score = 72.1 bits (169), Expect = 2e-12
Identities = 36/83 (43%), Positives = 49/83 (59%)
Frame = +2
Query: 257 TIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAY 436
TIACG +A+ + G+ + WG + GQLG + Q P V L V +VACG
Sbjct: 209 TIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGN-QPTPCRVAALQGIRVQRVACGYA 267
Query: 437 HSVALTNSGDLYSWGANSYGQCG 505
H++ LT+ G +Y+WGANSYGQ G
Sbjct: 268 HTLVLTDEGQVYAWGANSYGQLG 290
Score = 70.1 bits (164), Expect = 7e-12
Identities = 29/68 (42%), Positives = 43/68 (63%)
Frame = +2
Query: 302 GQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWG 481
G+ F+WG ++ QLGN H L+ K VI+VACG+YHS+ LT+ G++++WG
Sbjct: 118 GEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWG 177
Query: 482 ANSYGQCG 505
N+ GQ G
Sbjct: 178 YNNSGQVG 185
Score = 40.7 bits (91), Expect = 0.005
Identities = 29/105 (27%), Positives = 53/105 (50%), Gaps = 4/105 (3%)
Frame = +2
Query: 311 FSWGSDSMGQLGNNLG-AHAQDKPKFVKGLATKNVIQVACGAY-HSVALTNSGDLYSWGA 484
F G++ G LG LG + +P+ + L K + ++ G+ H V T G++++WG
Sbjct: 68 FVLGTNCCGCLG--LGDVQSTIEPRRLDSLNGKKIACLSYGSGPHIVLATTEGEVFTWGH 125
Query: 485 NSYGQC--GLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
N+Y Q G + CH+ ++L + + CG+ H+ VL+
Sbjct: 126 NAYSQLGNGTTNHGLVPCHIS--TNLSNKQVIEVACGSYHSLVLT 168
Score = 38.7 bits (86), Expect = 0.019
Identities = 21/51 (41%), Positives = 28/51 (54%)
Frame = +3
Query: 93 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKD 245
+Q VA G H+L L++ G +Y+ G N GQLG +S N P V KD
Sbjct: 259 VQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGNKS-NQSYPTPVTVEKD 308
Score = 33.9 bits (74), Expect = 0.55
Identities = 13/29 (44%), Positives = 21/29 (72%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLG 188
VA G +HSL L++ G +++ G N+ GQ+G
Sbjct: 157 VACGSYHSLVLTSDGEVFAWGYNNSGQVG 185
>AL157813-1|CAH70795.1| 551|Homo sapiens regulator of chromosome
condensation (RCC1) and BTB (POZ) domain containing pro
protein.
Length = 551
Score = 78.6 bits (185), Expect = 2e-14
Identities = 43/121 (35%), Positives = 68/121 (56%), Gaps = 3/121 (2%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG-LATKNVIQVACGAY 436
+ACG HSL + G+ F+WG ++ GQ+G+ + Q P+ V G L K V+ +ACG
Sbjct: 157 VACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVN-QPIPRRVTGCLQNKVVVTIACGQM 215
Query: 437 HSVALTNSGDLYSWGANSYGQCGL--ELYQTRKCHLQHISSLIGVPIALITCGNNHTFVL 610
+A+ ++G++Y WG N GQ GL Q C +++L G+ + + CG HT VL
Sbjct: 216 CCMAVVDTGEVYVWGYNGNGQLGLGNSGNQPTPC---RVAALQGIRVQRVACGYAHTLVL 272
Query: 611 S 613
+
Sbjct: 273 T 273
Score = 72.1 bits (169), Expect = 2e-12
Identities = 36/83 (43%), Positives = 49/83 (59%)
Frame = +2
Query: 257 TIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAY 436
TIACG +A+ + G+ + WG + GQLG + Q P V L V +VACG
Sbjct: 209 TIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGN-QPTPCRVAALQGIRVQRVACGYA 267
Query: 437 HSVALTNSGDLYSWGANSYGQCG 505
H++ LT+ G +Y+WGANSYGQ G
Sbjct: 268 HTLVLTDEGQVYAWGANSYGQLG 290
Score = 70.1 bits (164), Expect = 7e-12
Identities = 29/68 (42%), Positives = 43/68 (63%)
Frame = +2
Query: 302 GQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWG 481
G+ F+WG ++ QLGN H L+ K VI+VACG+YHS+ LT+ G++++WG
Sbjct: 118 GEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWG 177
Query: 482 ANSYGQCG 505
N+ GQ G
Sbjct: 178 YNNSGQVG 185
Score = 40.7 bits (91), Expect = 0.005
Identities = 29/105 (27%), Positives = 53/105 (50%), Gaps = 4/105 (3%)
Frame = +2
Query: 311 FSWGSDSMGQLGNNLG-AHAQDKPKFVKGLATKNVIQVACGAY-HSVALTNSGDLYSWGA 484
F G++ G LG LG + +P+ + L K + ++ G+ H V T G++++WG
Sbjct: 68 FVLGTNCCGCLG--LGDVQSTIEPRRLDSLNGKKIACLSYGSGPHIVLATTEGEVFTWGH 125
Query: 485 NSYGQC--GLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
N+Y Q G + CH+ ++L + + CG+ H+ VL+
Sbjct: 126 NAYSQLGNGTTNHGLVPCHIS--TNLSNKQVIEVACGSYHSLVLT 168
Score = 38.7 bits (86), Expect = 0.019
Identities = 21/51 (41%), Positives = 28/51 (54%)
Frame = +3
Query: 93 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKD 245
+Q VA G H+L L++ G +Y+ G N GQLG +S N P V KD
Sbjct: 259 VQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGNKS-NQSYPTPVTVEKD 308
Score = 33.9 bits (74), Expect = 0.55
Identities = 13/29 (44%), Positives = 21/29 (72%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLG 188
VA G +HSL L++ G +++ G N+ GQ+G
Sbjct: 157 VACGSYHSLVLTSDGEVFAWGYNNSGQVG 185
>AF224249-1|AAO27475.1| 328|Homo sapiens HERC2 protein.
Length = 328
Score = 78.6 bits (185), Expect = 2e-14
Identities = 47/123 (38%), Positives = 68/123 (55%), Gaps = 3/123 (2%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGA-- 433
IACG HS A+ G+ ++WG G+LG+ Q KPK VK L VIQVACG+
Sbjct: 142 IACGSSHSAALTSSGELYTWGLGEYGRLGHGDNT-TQLKPKMVKVLLGHRVIQVACGSRD 200
Query: 434 YHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHL-QHISSLIGVPIALITCGNNHTFVL 610
++ALT+ G ++SWG +G+ G + C++ Q+I L G + I CG + L
Sbjct: 201 AQTLALTDEGLVFSWGDGDFGKLGRG--GSEGCNIPQNIERLNGQGVCQIECGAQFSLAL 258
Query: 611 SKS 619
+KS
Sbjct: 259 TKS 261
Score = 77.8 bits (183), Expect = 3e-14
Identities = 39/115 (33%), Positives = 64/115 (55%)
Frame = +2
Query: 269 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 448
G +H+ A+ G+ F WG G+LG+ + DKP+ ++ L TK + +ACG+ HS A
Sbjct: 93 GGRHATALTVDGKVFWWGEGDDGKLGHFSRMNC-DKPRLIEALKTKRIRDIACGSSHSAA 151
Query: 449 LTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
LT+SG+LY+WG YG+ G T + + + L+G + + CG+ L+
Sbjct: 152 LTSSGELYTWGLGEYGRLG-HGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLA 205
Score = 77.0 bits (181), Expect = 6e-14
Identities = 35/82 (42%), Positives = 52/82 (63%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
I CG Q SLA+ + G ++WG +LG+ H + KP+ V+GL K ++ VA GA H
Sbjct: 248 IECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVR-KPQVVEGLRGKKIVHVAVGALH 306
Query: 440 SVALTNSGDLYSWGANSYGQCG 505
+A+T+SG +Y+WG N +GQ G
Sbjct: 307 CLAVTDSGQVYAWGDNDHGQQG 328
Score = 61.7 bits (143), Expect = 2e-09
Identities = 31/84 (36%), Positives = 49/84 (58%), Gaps = 2/84 (2%)
Frame = +2
Query: 260 IACGLQ--HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGA 433
+ACG + +LA+ + G FSWG G+LG G+ + P+ ++ L + V Q+ CGA
Sbjct: 194 VACGSRDAQTLALTDEGLVFSWGDGDFGKLGRG-GSEGCNIPQNIERLNGQGVCQIECGA 252
Query: 434 YHSVALTNSGDLYSWGANSYGQCG 505
S+ALT SG +++WG Y + G
Sbjct: 253 QFSLALTKSGVVWTWGKGDYFRLG 276
Score = 49.2 bits (112), Expect = 1e-05
Identities = 38/139 (27%), Positives = 65/139 (46%), Gaps = 3/139 (2%)
Frame = +2
Query: 212 KESSFSGNI*RLHNTTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVK 391
K SFS + L+ +A G + A+ G+ ++ G + G+LG + + P+ +
Sbjct: 19 KVPSFSETLSALNVVQVAGGSKSLFAVTVEGKVYACGEATNGRLGLGISSGTVPIPRQIT 78
Query: 392 GLATKNVIQVAC--GAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQH-ISSLIG 562
L++ V +VA G H+ ALT G ++ WG G+ G + C I +L
Sbjct: 79 ALSSYVVKKVAVHSGGRHATALTVDGKVFWWGEGDDGKLG--HFSRMNCDKPRLIEALKT 136
Query: 563 VPIALITCGNNHTFVLSKS 619
I I CG++H+ L+ S
Sbjct: 137 KRIRDIACGSSHSAALTSS 155
Score = 44.0 bits (99), Expect = 5e-04
Identities = 32/110 (29%), Positives = 50/110 (45%), Gaps = 2/110 (1%)
Frame = +2
Query: 317 WGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYG 496
WG + QLG G+ + P F + L+ NV+QVA G+ A+T G +Y+ G + G
Sbjct: 2 WGLNDKDQLGGLKGSKIK-VPSFSETLSALNVVQVAGGSKSLFAVTVEGKVYACGEATNG 60
Query: 497 QCGLELYQTRKCHLQHISSLIG--VPIALITCGNNHTFVLSKSRCGFWMG 640
+ GL + + I++L V + G H L+ FW G
Sbjct: 61 RLGLGISSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFWWG 110
>AF060219-1|AAC79987.1| 551|Homo sapiens RCC1-like G exchanging
factor RLG protein.
Length = 551
Score = 78.6 bits (185), Expect = 2e-14
Identities = 43/121 (35%), Positives = 68/121 (56%), Gaps = 3/121 (2%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG-LATKNVIQVACGAY 436
+ACG HSL + G+ F+WG ++ GQ+G+ + Q P+ V G L K V+ +ACG
Sbjct: 157 VACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVN-QPIPRRVTGCLQNKVVVTIACGQM 215
Query: 437 HSVALTNSGDLYSWGANSYGQCGL--ELYQTRKCHLQHISSLIGVPIALITCGNNHTFVL 610
+A+ ++G++Y WG N GQ GL Q C +++L G+ + + CG HT VL
Sbjct: 216 CCMAVVDTGEVYVWGYNGNGQLGLGNSGNQPTPC---RVAALQGIRVQRVACGYAHTLVL 272
Query: 611 S 613
+
Sbjct: 273 T 273
Score = 72.1 bits (169), Expect = 2e-12
Identities = 36/83 (43%), Positives = 49/83 (59%)
Frame = +2
Query: 257 TIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAY 436
TIACG +A+ + G+ + WG + GQLG + Q P V L V +VACG
Sbjct: 209 TIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGN-QPTPCRVAALQGIRVQRVACGYA 267
Query: 437 HSVALTNSGDLYSWGANSYGQCG 505
H++ LT+ G +Y+WGANSYGQ G
Sbjct: 268 HTLVLTDEGQVYAWGANSYGQLG 290
Score = 70.1 bits (164), Expect = 7e-12
Identities = 29/68 (42%), Positives = 43/68 (63%)
Frame = +2
Query: 302 GQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWG 481
G+ F+WG ++ QLGN H L+ K VI+VACG+YHS+ LT+ G++++WG
Sbjct: 118 GEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWG 177
Query: 482 ANSYGQCG 505
N+ GQ G
Sbjct: 178 YNNSGQVG 185
Score = 40.7 bits (91), Expect = 0.005
Identities = 29/105 (27%), Positives = 53/105 (50%), Gaps = 4/105 (3%)
Frame = +2
Query: 311 FSWGSDSMGQLGNNLG-AHAQDKPKFVKGLATKNVIQVACGAY-HSVALTNSGDLYSWGA 484
F G++ G LG LG + +P+ + L K + ++ G+ H V T G++++WG
Sbjct: 68 FVLGTNCCGCLG--LGDVQSTIEPRRLDSLNGKKIACLSYGSGPHIVLATTEGEVFTWGH 125
Query: 485 NSYGQC--GLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
N+Y Q G + CH+ ++L + + CG+ H+ VL+
Sbjct: 126 NAYSQLGNGTTNHGLVPCHIS--TNLSNKQVIEVACGSYHSLVLT 168
Score = 38.7 bits (86), Expect = 0.019
Identities = 21/51 (41%), Positives = 28/51 (54%)
Frame = +3
Query: 93 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKD 245
+Q VA G H+L L++ G +Y+ G N GQLG +S N P V KD
Sbjct: 259 VQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGNKS-NQSYPTPVTVEKD 308
Score = 33.9 bits (74), Expect = 0.55
Identities = 13/29 (44%), Positives = 21/29 (72%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLG 188
VA G +HSL L++ G +++ G N+ GQ+G
Sbjct: 157 VACGSYHSLVLTSDGEVFAWGYNNSGQVG 185
>AB209543-1|BAD92780.1| 556|Homo sapiens RCC1-like G exchanging
factor RLG variant protein.
Length = 556
Score = 78.6 bits (185), Expect = 2e-14
Identities = 43/121 (35%), Positives = 68/121 (56%), Gaps = 3/121 (2%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG-LATKNVIQVACGAY 436
+ACG HSL + G+ F+WG ++ GQ+G+ + Q P+ V G L K V+ +ACG
Sbjct: 162 VACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVN-QPIPRRVTGCLQNKVVVTIACGQM 220
Query: 437 HSVALTNSGDLYSWGANSYGQCGL--ELYQTRKCHLQHISSLIGVPIALITCGNNHTFVL 610
+A+ ++G++Y WG N GQ GL Q C +++L G+ + + CG HT VL
Sbjct: 221 CCMAVVDTGEVYVWGYNGNGQLGLGNSGNQPTPC---RVAALQGIRVQRVACGYAHTLVL 277
Query: 611 S 613
+
Sbjct: 278 T 278
Score = 72.1 bits (169), Expect = 2e-12
Identities = 36/83 (43%), Positives = 49/83 (59%)
Frame = +2
Query: 257 TIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAY 436
TIACG +A+ + G+ + WG + GQLG + Q P V L V +VACG
Sbjct: 214 TIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGN-QPTPCRVAALQGIRVQRVACGYA 272
Query: 437 HSVALTNSGDLYSWGANSYGQCG 505
H++ LT+ G +Y+WGANSYGQ G
Sbjct: 273 HTLVLTDEGQVYAWGANSYGQLG 295
Score = 70.1 bits (164), Expect = 7e-12
Identities = 29/68 (42%), Positives = 43/68 (63%)
Frame = +2
Query: 302 GQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWG 481
G+ F+WG ++ QLGN H L+ K VI+VACG+YHS+ LT+ G++++WG
Sbjct: 123 GEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWG 182
Query: 482 ANSYGQCG 505
N+ GQ G
Sbjct: 183 YNNSGQVG 190
Score = 40.7 bits (91), Expect = 0.005
Identities = 29/105 (27%), Positives = 53/105 (50%), Gaps = 4/105 (3%)
Frame = +2
Query: 311 FSWGSDSMGQLGNNLG-AHAQDKPKFVKGLATKNVIQVACGAY-HSVALTNSGDLYSWGA 484
F G++ G LG LG + +P+ + L K + ++ G+ H V T G++++WG
Sbjct: 73 FVLGTNCCGCLG--LGDVQSTIEPRRLDSLNGKKIACLSYGSGPHIVLATTEGEVFTWGH 130
Query: 485 NSYGQC--GLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
N+Y Q G + CH+ ++L + + CG+ H+ VL+
Sbjct: 131 NAYSQLGNGTTNHGLVPCHIS--TNLSNKQVIEVACGSYHSLVLT 173
Score = 38.7 bits (86), Expect = 0.019
Identities = 21/51 (41%), Positives = 28/51 (54%)
Frame = +3
Query: 93 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKD 245
+Q VA G H+L L++ G +Y+ G N GQLG +S N P V KD
Sbjct: 264 VQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGNKS-NQSYPTPVTVEKD 313
Score = 33.9 bits (74), Expect = 0.55
Identities = 13/29 (44%), Positives = 21/29 (72%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLG 188
VA G +HSL L++ G +++ G N+ GQ+G
Sbjct: 162 VACGSYHSLVLTSDGEVFAWGYNNSGQVG 190
>AC004460-2|AAC06339.1| 371|Homo sapiens WUGSC:H_DJ1086D14.2
protein.
Length = 371
Score = 78.2 bits (184), Expect = 3e-14
Identities = 39/114 (34%), Positives = 63/114 (55%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
I CG Q LA+ + G ++WG +LG+ H + KP+ V+GL K ++ VA GA H
Sbjct: 39 IECGAQFLLALTKSGVVWTWGKGDYFRLGHRSDVHVR-KPQVVEGLRGKKIVHVAVGAQH 97
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHT 601
+A+ +SG +Y+WG N +GQ G + + + L G I + CG++H+
Sbjct: 98 CLAVMDSGQVYAWGDNDHGQQGNGTTTVNRKPML-VQGLEGQKIMCVACGSSHS 150
Score = 58.0 bits (134), Expect = 3e-08
Identities = 28/65 (43%), Positives = 39/65 (60%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+A G QH LA+ + GQ ++WG + GQ GN KP V+GL + ++ VACG+ H
Sbjct: 91 VAVGAQHCLAVMDSGQVYAWGDNDHGQQGNGTTT-VNRKPMLVQGLEGQKIMCVACGSSH 149
Query: 440 SVALT 454
SVA T
Sbjct: 150 SVAWT 154
Score = 53.6 bits (123), Expect = 6e-07
Identities = 34/107 (31%), Positives = 50/107 (46%), Gaps = 1/107 (0%)
Frame = +2
Query: 302 GQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWG 481
G FSWG G+LG G+ + P+ ++ L + V Q+ CGA +ALT SG +++WG
Sbjct: 1 GLVFSWGDGDFGKLGRG-GSEGCNIPQNIERLNGQGVCQIECGAQFLLALTKSGVVWTWG 59
Query: 482 ANSYGQCGLEL-YQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
Y + G RK Q + L G I + G H + S
Sbjct: 60 KGDYFRLGHRSDVHVRK--PQVVEGLRGKKIVHVAVGAQHCLAVMDS 104
>AF225407-1|AAO27483.1| 409|Homo sapiens HERC2 protein.
Length = 409
Score = 77.0 bits (181), Expect = 6e-14
Identities = 39/121 (32%), Positives = 65/121 (53%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ CG Q S+A+ + G ++WG +LG+ H + +P+ V+GL K VI +A G+ H
Sbjct: 106 VECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVR-RPRQVQGLQGKKVIAIATGSLH 164
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
V T G++Y+WG N GQ G + + +++L G + + CG+ HT S S
Sbjct: 165 CVCCTEDGEVYTWGDNDEGQLGDGTTNAIQ-RPRLVAALQGKKVNRVACGSAHTLAWSTS 223
Query: 620 R 622
+
Sbjct: 224 K 224
Score = 67.7 bits (158), Expect = 4e-11
Identities = 39/128 (30%), Positives = 65/128 (50%), Gaps = 2/128 (1%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGA--Y 436
A G HS + G ++WG G+LG++ + Q KPK V+ L V+ +ACG+
Sbjct: 1 AAGGAHSACVTAAGDLYTWGKGRYGRLGHS-DSEDQLKPKLVEALQGHRVVDIACGSGDA 59
Query: 437 HSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSK 616
++ LT+ ++SWG YG+ G K ++ I SL G+ + + CG+ + L+K
Sbjct: 60 QTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMK-IDSLTGLGVVKVECGSQFSVALTK 118
Query: 617 SRCGFWMG 640
S + G
Sbjct: 119 SGAVYTWG 126
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Frame = +2
Query: 260 IACGL--QHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGA 433
IACG +L + + +SWG G+LG G+ P + L V++V CG+
Sbjct: 52 IACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRG-GSDGCKVPMKIDSLTGLGVVKVECGS 110
Query: 434 YHSVALTNSGDLYSWGANSYGQCG 505
SVALT SG +Y+WG Y + G
Sbjct: 111 QFSVALTKSGAVYTWGKGDYHRLG 134
Score = 36.3 bits (80), Expect = 0.10
Identities = 17/51 (33%), Positives = 27/51 (52%)
Frame = +3
Query: 45 DLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQT 197
D V +P + + + A+A G H + + G +Y+ G+ND GQLG T
Sbjct: 139 DHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGT 189
Score = 32.3 bits (70), Expect = 1.7
Identities = 17/46 (36%), Positives = 27/46 (58%)
Frame = +3
Query: 105 AAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFK 242
AAG HS ++ +G LY+ G G+LG ++S++ P LVE +
Sbjct: 1 AAGGAHSACVTAAGDLYTWGKGRYGRLG-HSDSEDQLKPKLVEALQ 45
>AL356741-1|CAH74146.1| 907|Homo sapiens hect domain and RLD 4
protein.
Length = 907
Score = 73.7 bits (173), Expect = 6e-13
Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 2/123 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+A G HS + G F WG + GQLG N + + P +K L ++ ++ + CG H
Sbjct: 45 VAAGGAHSFVLTLSGAIFGWGRNKFGQLGLN-DENDRYVPNLLKSLRSQKIVYICCGEDH 103
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHT--FVLS 613
+ ALT G ++++GA YGQ G + + + + + L+G + I CG HT FV S
Sbjct: 104 TAALTKEGGVFTFGAGGYGQLG-HNSTSHEINPRKVFELMGSIVTEIACGRQHTSAFVPS 162
Query: 614 KSR 622
R
Sbjct: 163 SGR 165
Score = 72.5 bits (170), Expect = 1e-12
Identities = 41/110 (37%), Positives = 51/110 (46%)
Frame = +2
Query: 311 FSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANS 490
F WG + GQLG Q P+ +K L +QVA G HS LT SG ++ WG N
Sbjct: 9 FCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGRNK 68
Query: 491 YGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKSRCGFWMG 640
+GQ GL R + SL I I CG +HT L+K F G
Sbjct: 69 FGQLGLNDENDRYVP-NLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFG 117
Score = 47.2 bits (107), Expect = 6e-05
Identities = 21/62 (33%), Positives = 34/62 (54%)
Frame = +2
Query: 455 NSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKSRCGFW 634
++ +++ WG N YGQ GL ++ Q + SL+G+P + G H+FVL+ S F
Sbjct: 4 SASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFG 63
Query: 635 MG 640
G
Sbjct: 64 WG 65
Score = 35.5 bits (78), Expect = 0.18
Identities = 17/35 (48%), Positives = 21/35 (60%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESD 206
VAAG HS L+ SG ++ G N GQLG E+D
Sbjct: 45 VAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDEND 79
Score = 31.1 bits (67), Expect = 3.9
Identities = 19/48 (39%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Frame = +2
Query: 254 TTIACGLQHSLA-IDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG 394
T IACG QH+ A + G+ +S+G GQLG ++ + P VKG
Sbjct: 147 TEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSN-RKSPFTVKG 193
Score = 30.3 bits (65), Expect = 6.8
Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Frame = +3
Query: 93 IQAVAAGEFH-SLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 233
+ +A G H S ++ +SG +YS G GQLG + S N K+P V+
Sbjct: 146 VTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTS-NRKSPFTVK 192
>AL133551-1|CAI16031.1| 907|Homo sapiens hect domain and RLD 4
protein.
Length = 907
Score = 73.7 bits (173), Expect = 6e-13
Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 2/123 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+A G HS + G F WG + GQLG N + + P +K L ++ ++ + CG H
Sbjct: 45 VAAGGAHSFVLTLSGAIFGWGRNKFGQLGLN-DENDRYVPNLLKSLRSQKIVYICCGEDH 103
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHT--FVLS 613
+ ALT G ++++GA YGQ G + + + + + L+G + I CG HT FV S
Sbjct: 104 TAALTKEGGVFTFGAGGYGQLG-HNSTSHEINPRKVFELMGSIVTEIACGRQHTSAFVPS 162
Query: 614 KSR 622
R
Sbjct: 163 SGR 165
Score = 72.5 bits (170), Expect = 1e-12
Identities = 41/110 (37%), Positives = 51/110 (46%)
Frame = +2
Query: 311 FSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANS 490
F WG + GQLG Q P+ +K L +QVA G HS LT SG ++ WG N
Sbjct: 9 FCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGRNK 68
Query: 491 YGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKSRCGFWMG 640
+GQ GL R + SL I I CG +HT L+K F G
Sbjct: 69 FGQLGLNDENDRYVP-NLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFG 117
Score = 47.2 bits (107), Expect = 6e-05
Identities = 21/62 (33%), Positives = 34/62 (54%)
Frame = +2
Query: 455 NSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKSRCGFW 634
++ +++ WG N YGQ GL ++ Q + SL+G+P + G H+FVL+ S F
Sbjct: 4 SASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFG 63
Query: 635 MG 640
G
Sbjct: 64 WG 65
Score = 35.5 bits (78), Expect = 0.18
Identities = 17/35 (48%), Positives = 21/35 (60%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESD 206
VAAG HS L+ SG ++ G N GQLG E+D
Sbjct: 45 VAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDEND 79
Score = 31.1 bits (67), Expect = 3.9
Identities = 19/48 (39%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Frame = +2
Query: 254 TTIACGLQHSLA-IDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG 394
T IACG QH+ A + G+ +S+G GQLG ++ + P VKG
Sbjct: 147 TEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSN-RKSPFTVKG 193
Score = 30.3 bits (65), Expect = 6.8
Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Frame = +3
Query: 93 IQAVAAGEFH-SLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 233
+ +A G H S ++ +SG +YS G GQLG + S N K+P V+
Sbjct: 146 VTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTS-NRKSPFTVK 192
>BC142946-1|AAI42947.1| 457|Homo sapiens RCC2 protein protein.
Length = 457
Score = 68.5 bits (160), Expect = 2e-11
Identities = 36/111 (32%), Positives = 59/111 (53%)
Frame = +2
Query: 278 HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTN 457
HSL I G+ +SWG + GQLG+ + P+ ++GL+ + ++ ACG H++ALT
Sbjct: 96 HSLLITTEGKLWSWGRNEKGQLGHG-DTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTE 154
Query: 458 SGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVL 610
+G ++++G N GQ GL QT G PI + CG + ++
Sbjct: 155 TGSVFAFGENKMGQLGLG-NQTDAVPSPAQIMYNGQPITKMACGAEFSMIM 204
Score = 60.1 bits (139), Expect = 7e-09
Identities = 31/81 (38%), Positives = 45/81 (55%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 442
ACG H+LA+ E G F++G + MGQLG A P + + + ++ACGA S
Sbjct: 143 ACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQIM-YNGQPITKMACGAEFS 201
Query: 443 VALTNSGDLYSWGANSYGQCG 505
+ + G+LYS+G YGQ G
Sbjct: 202 MIMDCKGNLYSFGCPEYGQLG 222
Score = 48.0 bits (109), Expect = 3e-05
Identities = 34/102 (33%), Positives = 47/102 (46%), Gaps = 2/102 (1%)
Frame = +2
Query: 341 LGNNL-GAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLELY 517
LG NL G H + G+ + V+ +C A HS+ +T G L+SWG N GQ G
Sbjct: 67 LGQNLWGPHRYG---CLAGVRVRTVVSGSCAA-HSLLITTEGKLWSWGRNEKGQLGHG-- 120
Query: 518 QTRKCHLQH-ISSLIGVPIALITCGNNHTFVLSKSRCGFWMG 640
T++ I L I CG NHT L+++ F G
Sbjct: 121 DTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFG 162
Score = 45.2 bits (102), Expect = 2e-04
Identities = 35/107 (32%), Positives = 51/107 (47%), Gaps = 23/107 (21%)
Frame = +2
Query: 254 TTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLG----AHAQ----------------- 370
T +ACG + S+ +D G +S+G GQLG+N A AQ
Sbjct: 192 TKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFI 251
Query: 371 DKPKFVKGLATKNVI--QVACGAYHSVALTNSGDLYSWGANSYGQCG 505
+K K + L NV+ VACGA H++ L + ++SWG YG+ G
Sbjct: 252 EKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYGRLG 298
Score = 45.2 bits (102), Expect = 2e-04
Identities = 26/81 (32%), Positives = 42/81 (51%), Gaps = 4/81 (4%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK--PKFVK--GLATKNVIQVAC 427
+ACG H+L +D + FSWG G+LG+ A +D+ P+ VK + ++
Sbjct: 270 VACGANHTLVLDSQKRVFSWGFGGYGRLGH---AEQKDEMVPRLVKLFDFPGRGASRIYA 326
Query: 428 GAYHSVALTNSGDLYSWGANS 490
G S A++ G L+ WGA +
Sbjct: 327 GYTCSFAVSEVGGLFFWGATN 347
Score = 38.3 bits (85), Expect = 0.026
Identities = 20/63 (31%), Positives = 34/63 (53%)
Frame = +3
Query: 42 TDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNP 221
T V P L + + I + A G H+L L+ +G +++ G N +GQLG ++D +P
Sbjct: 122 TKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSP 181
Query: 222 ALV 230
A +
Sbjct: 182 AQI 184
Score = 31.1 bits (67), Expect = 3.9
Identities = 15/38 (39%), Positives = 23/38 (60%)
Frame = +3
Query: 120 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 233
HSL ++ G L+S G N+ GQLG ++ + P L+E
Sbjct: 96 HSLLITTEGKLWSWGRNEKGQLG-HGDTKRVEAPRLIE 132
>BC053908-1|AAH53908.1| 522|Homo sapiens RCC2 protein protein.
Length = 522
Score = 68.5 bits (160), Expect = 2e-11
Identities = 36/111 (32%), Positives = 59/111 (53%)
Frame = +2
Query: 278 HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTN 457
HSL I G+ +SWG + GQLG+ + P+ ++GL+ + ++ ACG H++ALT
Sbjct: 161 HSLLITTEGKLWSWGRNEKGQLGHG-DTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTE 219
Query: 458 SGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVL 610
+G ++++G N GQ GL QT G PI + CG + ++
Sbjct: 220 TGSVFAFGENKMGQLGLG-NQTDAVPSPAQIMYNGQPITKMACGAEFSMIM 269
Score = 60.1 bits (139), Expect = 7e-09
Identities = 31/81 (38%), Positives = 45/81 (55%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 442
ACG H+LA+ E G F++G + MGQLG A P + + + ++ACGA S
Sbjct: 208 ACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQIM-YNGQPITKMACGAEFS 266
Query: 443 VALTNSGDLYSWGANSYGQCG 505
+ + G+LYS+G YGQ G
Sbjct: 267 MIMDCKGNLYSFGCPEYGQLG 287
Score = 48.0 bits (109), Expect = 3e-05
Identities = 34/102 (33%), Positives = 47/102 (46%), Gaps = 2/102 (1%)
Frame = +2
Query: 341 LGNNL-GAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLELY 517
LG NL G H + G+ + V+ +C A HS+ +T G L+SWG N GQ G
Sbjct: 132 LGQNLWGPHRYG---CLAGVRVRTVVSGSCAA-HSLLITTEGKLWSWGRNEKGQLGHG-- 185
Query: 518 QTRKCHLQH-ISSLIGVPIALITCGNNHTFVLSKSRCGFWMG 640
T++ I L I CG NHT L+++ F G
Sbjct: 186 DTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFG 227
Score = 46.8 bits (106), Expect = 7e-05
Identities = 27/81 (33%), Positives = 42/81 (51%), Gaps = 4/81 (4%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK--PKFVK--GLATKNVIQVAC 427
+ACG H+L +D + FSWG G+LG+ A +D+ P+ VK + Q+
Sbjct: 335 VACGANHTLVLDSQKRVFSWGFGGYGRLGH---AEQKDEMVPRLVKLFDFPGRGASQIYA 391
Query: 428 GAYHSVALTNSGDLYSWGANS 490
G S A++ G L+ WGA +
Sbjct: 392 GYTCSFAVSEVGGLFFWGATN 412
Score = 45.2 bits (102), Expect = 2e-04
Identities = 35/107 (32%), Positives = 51/107 (47%), Gaps = 23/107 (21%)
Frame = +2
Query: 254 TTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLG----AHAQ----------------- 370
T +ACG + S+ +D G +S+G GQLG+N A AQ
Sbjct: 257 TKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFI 316
Query: 371 DKPKFVKGLATKNVI--QVACGAYHSVALTNSGDLYSWGANSYGQCG 505
+K K + L NV+ VACGA H++ L + ++SWG YG+ G
Sbjct: 317 EKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYGRLG 363
Score = 38.3 bits (85), Expect = 0.026
Identities = 20/63 (31%), Positives = 34/63 (53%)
Frame = +3
Query: 42 TDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNP 221
T V P L + + I + A G H+L L+ +G +++ G N +GQLG ++D +P
Sbjct: 187 TKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSP 246
Query: 222 ALV 230
A +
Sbjct: 247 AQI 249
Score = 31.1 bits (67), Expect = 3.9
Identities = 15/38 (39%), Positives = 23/38 (60%)
Frame = +3
Query: 120 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 233
HSL ++ G L+S G N+ GQLG ++ + P L+E
Sbjct: 161 HSLLITTEGKLWSWGRNEKGQLG-HGDTKRVEAPRLIE 197
>BC042141-1|AAH42141.1| 522|Homo sapiens regulator of chromosome
condensation 2 protein.
Length = 522
Score = 68.5 bits (160), Expect = 2e-11
Identities = 36/111 (32%), Positives = 59/111 (53%)
Frame = +2
Query: 278 HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTN 457
HSL I G+ +SWG + GQLG+ + P+ ++GL+ + ++ ACG H++ALT
Sbjct: 161 HSLLITTEGKLWSWGRNEKGQLGHG-DTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTE 219
Query: 458 SGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVL 610
+G ++++G N GQ GL QT G PI + CG + ++
Sbjct: 220 TGSVFAFGENKMGQLGLG-NQTDAVPSPAQIMYNGQPITKMACGAEFSMIM 269
Score = 60.1 bits (139), Expect = 7e-09
Identities = 31/81 (38%), Positives = 45/81 (55%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 442
ACG H+LA+ E G F++G + MGQLG A P + + + ++ACGA S
Sbjct: 208 ACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQIM-YNGQPITKMACGAEFS 266
Query: 443 VALTNSGDLYSWGANSYGQCG 505
+ + G+LYS+G YGQ G
Sbjct: 267 MIMDCKGNLYSFGCPEYGQLG 287
Score = 48.0 bits (109), Expect = 3e-05
Identities = 34/102 (33%), Positives = 47/102 (46%), Gaps = 2/102 (1%)
Frame = +2
Query: 341 LGNNL-GAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLELY 517
LG NL G H + G+ + V+ +C A HS+ +T G L+SWG N GQ G
Sbjct: 132 LGQNLWGPHRYG---CLAGVRVRTVVSGSCAA-HSLLITTEGKLWSWGRNEKGQLGHG-- 185
Query: 518 QTRKCHLQH-ISSLIGVPIALITCGNNHTFVLSKSRCGFWMG 640
T++ I L I CG NHT L+++ F G
Sbjct: 186 DTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFG 227
Score = 46.8 bits (106), Expect = 7e-05
Identities = 27/81 (33%), Positives = 42/81 (51%), Gaps = 4/81 (4%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK--PKFVK--GLATKNVIQVAC 427
+ACG H+L +D + FSWG G+LG+ A +D+ P+ VK + Q+
Sbjct: 335 VACGANHTLVLDSQKRVFSWGFGGYGRLGH---AEQKDEMVPRLVKLFDFPGRGASQIYA 391
Query: 428 GAYHSVALTNSGDLYSWGANS 490
G S A++ G L+ WGA +
Sbjct: 392 GYTCSFAVSEVGGLFFWGATN 412
Score = 45.2 bits (102), Expect = 2e-04
Identities = 35/107 (32%), Positives = 51/107 (47%), Gaps = 23/107 (21%)
Frame = +2
Query: 254 TTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLG----AHAQ----------------- 370
T +ACG + S+ +D G +S+G GQLG+N A AQ
Sbjct: 257 TKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFI 316
Query: 371 DKPKFVKGLATKNVI--QVACGAYHSVALTNSGDLYSWGANSYGQCG 505
+K K + L NV+ VACGA H++ L + ++SWG YG+ G
Sbjct: 317 EKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYGRLG 363
Score = 38.3 bits (85), Expect = 0.026
Identities = 20/63 (31%), Positives = 34/63 (53%)
Frame = +3
Query: 42 TDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNP 221
T V P L + + I + A G H+L L+ +G +++ G N +GQLG ++D +P
Sbjct: 187 TKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSP 246
Query: 222 ALV 230
A +
Sbjct: 247 AQI 249
Score = 31.1 bits (67), Expect = 3.9
Identities = 15/38 (39%), Positives = 23/38 (60%)
Frame = +3
Query: 120 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 233
HSL ++ G L+S G N+ GQLG ++ + P L+E
Sbjct: 161 HSLLITTEGKLWSWGRNEKGQLG-HGDTKRVEAPRLIE 197
>AL359612-1|CAB94882.1| 333|Homo sapiens hypothetical protein
protein.
Length = 333
Score = 68.5 bits (160), Expect = 2e-11
Identities = 36/111 (32%), Positives = 59/111 (53%)
Frame = +2
Query: 278 HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTN 457
HSL I G+ +SWG + GQLG+ + P+ ++GL+ + ++ ACG H++ALT
Sbjct: 17 HSLLITTEGKLWSWGRNEKGQLGHG-DTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTE 75
Query: 458 SGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVL 610
+G ++++G N GQ GL QT G PI + CG + ++
Sbjct: 76 TGSVFAFGENKMGQLGLG-NQTDAVPSPAQIMYNGQPITKMACGAEFSMIM 125
Score = 60.1 bits (139), Expect = 7e-09
Identities = 31/81 (38%), Positives = 45/81 (55%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 442
ACG H+LA+ E G F++G + MGQLG A P + + + ++ACGA S
Sbjct: 64 ACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQIM-YNGQPITKMACGAEFS 122
Query: 443 VALTNSGDLYSWGANSYGQCG 505
+ + G+LYS+G YGQ G
Sbjct: 123 MIMDCKGNLYSFGCPEYGQLG 143
Score = 46.8 bits (106), Expect = 7e-05
Identities = 27/81 (33%), Positives = 42/81 (51%), Gaps = 4/81 (4%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK--PKFVK--GLATKNVIQVAC 427
+ACG H+L +D + FSWG G+LG+ A +D+ P+ VK + Q+
Sbjct: 191 VACGANHTLVLDSQKRVFSWGFGGYGRLGH---AEQKDEMVPRLVKLFDFPGRGASQIYA 247
Query: 428 GAYHSVALTNSGDLYSWGANS 490
G S A++ G L+ WGA +
Sbjct: 248 GYTCSFAVSEVGGLFFWGATN 268
Score = 45.2 bits (102), Expect = 2e-04
Identities = 35/107 (32%), Positives = 51/107 (47%), Gaps = 23/107 (21%)
Frame = +2
Query: 254 TTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLG----AHAQ----------------- 370
T +ACG + S+ +D G +S+G GQLG+N A AQ
Sbjct: 113 TKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFI 172
Query: 371 DKPKFVKGLATKNVI--QVACGAYHSVALTNSGDLYSWGANSYGQCG 505
+K K + L NV+ VACGA H++ L + ++SWG YG+ G
Sbjct: 173 EKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYGRLG 219
Score = 44.8 bits (101), Expect = 3e-04
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Frame = +2
Query: 404 KNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQH-ISSLIGVPIALI 580
+ V+ +C A HS+ +T G L+SWG N GQ G T++ I L I
Sbjct: 7 RTVVSGSCAA-HSLLITTEGKLWSWGRNEKGQLGHG--DTKRVEAPRLIEGLSHEVIVSA 63
Query: 581 TCGNNHTFVLSKSRCGFWMG 640
CG NHT L+++ F G
Sbjct: 64 ACGRNHTLALTETGSVFAFG 83
Score = 38.3 bits (85), Expect = 0.026
Identities = 20/63 (31%), Positives = 34/63 (53%)
Frame = +3
Query: 42 TDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNP 221
T V P L + + I + A G H+L L+ +G +++ G N +GQLG ++D +P
Sbjct: 43 TKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSP 102
Query: 222 ALV 230
A +
Sbjct: 103 AQI 105
Score = 31.1 bits (67), Expect = 3.9
Identities = 15/38 (39%), Positives = 23/38 (60%)
Frame = +3
Query: 120 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 233
HSL ++ G L+S G N+ GQLG ++ + P L+E
Sbjct: 17 HSLLITTEGKLWSWGRNEKGQLG-HGDTKRVEAPRLIE 53
>AJ421269-1|CAD13148.1| 522|Homo sapiens RCC1-like protein protein.
Length = 522
Score = 68.5 bits (160), Expect = 2e-11
Identities = 36/111 (32%), Positives = 59/111 (53%)
Frame = +2
Query: 278 HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTN 457
HSL I G+ +SWG + GQLG+ + P+ ++GL+ + ++ ACG H++ALT
Sbjct: 161 HSLLITTEGKLWSWGRNEKGQLGHG-DTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTE 219
Query: 458 SGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVL 610
+G ++++G N GQ GL QT G PI + CG + ++
Sbjct: 220 TGSVFAFGENKMGQLGLG-NQTDAVPSPAQIMYNGQPITKMACGAEFSMIM 269
Score = 60.1 bits (139), Expect = 7e-09
Identities = 31/81 (38%), Positives = 45/81 (55%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 442
ACG H+LA+ E G F++G + MGQLG A P + + + ++ACGA S
Sbjct: 208 ACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQIM-YNGQPITKMACGAEFS 266
Query: 443 VALTNSGDLYSWGANSYGQCG 505
+ + G+LYS+G YGQ G
Sbjct: 267 MIMDCKGNLYSFGCPEYGQLG 287
Score = 48.0 bits (109), Expect = 3e-05
Identities = 34/102 (33%), Positives = 47/102 (46%), Gaps = 2/102 (1%)
Frame = +2
Query: 341 LGNNL-GAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLELY 517
LG NL G H + G+ + V+ +C A HS+ +T G L+SWG N GQ G
Sbjct: 132 LGQNLWGPHRYG---CLAGVRVRTVVSGSCAA-HSLLITTEGKLWSWGRNEKGQLGHG-- 185
Query: 518 QTRKCHLQH-ISSLIGVPIALITCGNNHTFVLSKSRCGFWMG 640
T++ I L I CG NHT L+++ F G
Sbjct: 186 DTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFG 227
Score = 46.8 bits (106), Expect = 7e-05
Identities = 27/81 (33%), Positives = 42/81 (51%), Gaps = 4/81 (4%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK--PKFVK--GLATKNVIQVAC 427
+ACG H+L +D + FSWG G+LG+ A +D+ P+ VK + Q+
Sbjct: 335 VACGANHTLVLDSQKRVFSWGFGGYGRLGH---AEQKDEMVPRLVKLFDFPGRGASQIYA 391
Query: 428 GAYHSVALTNSGDLYSWGANS 490
G S A++ G L+ WGA +
Sbjct: 392 GYTCSFAVSEVGGLFFWGATN 412
Score = 45.2 bits (102), Expect = 2e-04
Identities = 35/107 (32%), Positives = 51/107 (47%), Gaps = 23/107 (21%)
Frame = +2
Query: 254 TTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLG----AHAQ----------------- 370
T +ACG + S+ +D G +S+G GQLG+N A AQ
Sbjct: 257 TKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFI 316
Query: 371 DKPKFVKGLATKNVI--QVACGAYHSVALTNSGDLYSWGANSYGQCG 505
+K K + L NV+ VACGA H++ L + ++SWG YG+ G
Sbjct: 317 EKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYGRLG 363
Score = 38.3 bits (85), Expect = 0.026
Identities = 20/63 (31%), Positives = 34/63 (53%)
Frame = +3
Query: 42 TDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNP 221
T V P L + + I + A G H+L L+ +G +++ G N +GQLG ++D +P
Sbjct: 187 TKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSP 246
Query: 222 ALV 230
A +
Sbjct: 247 AQI 249
Score = 31.1 bits (67), Expect = 3.9
Identities = 15/38 (39%), Positives = 23/38 (60%)
Frame = +3
Query: 120 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 233
HSL ++ G L+S G N+ GQLG ++ + P L+E
Sbjct: 161 HSLLITTEGKLWSWGRNEKGQLG-HGDTKRVEAPRLIE 197
>AB040903-1|BAA95994.1| 564|Homo sapiens KIAA1470 protein protein.
Length = 564
Score = 68.5 bits (160), Expect = 2e-11
Identities = 36/111 (32%), Positives = 59/111 (53%)
Frame = +2
Query: 278 HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTN 457
HSL I G+ +SWG + GQLG+ + P+ ++GL+ + ++ ACG H++ALT
Sbjct: 203 HSLLITTEGKLWSWGRNEKGQLGHG-DTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTE 261
Query: 458 SGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVL 610
+G ++++G N GQ GL QT G PI + CG + ++
Sbjct: 262 TGSVFAFGENKMGQLGLG-NQTDAVPSPAQIMYNGQPITKMACGAEFSMIM 311
Score = 60.1 bits (139), Expect = 7e-09
Identities = 31/81 (38%), Positives = 45/81 (55%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 442
ACG H+LA+ E G F++G + MGQLG A P + + + ++ACGA S
Sbjct: 250 ACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQIM-YNGQPITKMACGAEFS 308
Query: 443 VALTNSGDLYSWGANSYGQCG 505
+ + G+LYS+G YGQ G
Sbjct: 309 MIMDCKGNLYSFGCPEYGQLG 329
Score = 48.0 bits (109), Expect = 3e-05
Identities = 34/102 (33%), Positives = 47/102 (46%), Gaps = 2/102 (1%)
Frame = +2
Query: 341 LGNNL-GAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLELY 517
LG NL G H + G+ + V+ +C A HS+ +T G L+SWG N GQ G
Sbjct: 174 LGQNLWGPHRYG---CLAGVRVRTVVSGSCAA-HSLLITTEGKLWSWGRNEKGQLGHG-- 227
Query: 518 QTRKCHLQH-ISSLIGVPIALITCGNNHTFVLSKSRCGFWMG 640
T++ I L I CG NHT L+++ F G
Sbjct: 228 DTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFG 269
Score = 46.8 bits (106), Expect = 7e-05
Identities = 27/81 (33%), Positives = 42/81 (51%), Gaps = 4/81 (4%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK--PKFVK--GLATKNVIQVAC 427
+ACG H+L +D + FSWG G+LG+ A +D+ P+ VK + Q+
Sbjct: 377 VACGANHTLVLDSQKRVFSWGFGGYGRLGH---AEQKDEMVPRLVKLFDFPGRGASQIYA 433
Query: 428 GAYHSVALTNSGDLYSWGANS 490
G S A++ G L+ WGA +
Sbjct: 434 GYTCSFAVSEVGGLFFWGATN 454
Score = 45.2 bits (102), Expect = 2e-04
Identities = 35/107 (32%), Positives = 51/107 (47%), Gaps = 23/107 (21%)
Frame = +2
Query: 254 TTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLG----AHAQ----------------- 370
T +ACG + S+ +D G +S+G GQLG+N A AQ
Sbjct: 299 TKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFI 358
Query: 371 DKPKFVKGLATKNVI--QVACGAYHSVALTNSGDLYSWGANSYGQCG 505
+K K + L NV+ VACGA H++ L + ++SWG YG+ G
Sbjct: 359 EKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYGRLG 405
Score = 38.3 bits (85), Expect = 0.026
Identities = 20/63 (31%), Positives = 34/63 (53%)
Frame = +3
Query: 42 TDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNP 221
T V P L + + I + A G H+L L+ +G +++ G N +GQLG ++D +P
Sbjct: 229 TKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSP 288
Query: 222 ALV 230
A +
Sbjct: 289 AQI 291
Score = 31.1 bits (67), Expect = 3.9
Identities = 15/38 (39%), Positives = 23/38 (60%)
Frame = +3
Query: 120 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 233
HSL ++ G L+S G N+ GQLG ++ + P L+E
Sbjct: 203 HSLLITTEGKLWSWGRNEKGQLG-HGDTKRVEAPRLIE 239
>BC071576-1|AAH71576.1| 1237|Homo sapiens ALS2 protein protein.
Length = 1237
Score = 65.3 bits (152), Expect = 2e-10
Identities = 41/101 (40%), Positives = 53/101 (52%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 442
A L SL I+ W +WG GQLG+ + +P VK L K VI + G YHS
Sbjct: 517 ADALLPSLRIEVW----TWGKGKEGQLGHG-DVLPRLQPLCVKCLDGKEVIHLEAGGYHS 571
Query: 443 VALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGV 565
+ALT +YSWG+N++GQ G + T L ISS GV
Sbjct: 572 LALTAKSQVYSWGSNTFGQLGHSDFPTTVPRLAKISSENGV 612
Score = 58.8 bits (136), Expect = 2e-08
Identities = 40/126 (31%), Positives = 60/126 (47%), Gaps = 6/126 (4%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 442
A G++H + + E G+ +S+G+ + P L + VI VA G++HS
Sbjct: 47 ALGVKHGVLLTEDGEVYSFGTLPWRSGPVEI---CPSSPILENALVGQYVITVATGSFHS 103
Query: 443 VALTNSGDLYSWGANSYGQCGL--ELYQTRKCHL----QHISSLIGVPIALITCGNNHTF 604
A+T++G Y WG NS GQC + + Y + S L+ V I + CG HT
Sbjct: 104 GAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQLACGEEHTL 163
Query: 605 VLSKSR 622
LS SR
Sbjct: 164 ALSISR 169
Score = 52.4 bits (120), Expect = 1e-06
Identities = 28/64 (43%), Positives = 42/64 (65%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG +H+LA+ + ++WG+ QLG A KP+ V+ LA + V+QVACGA+H
Sbjct: 155 LACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLAGRVVLQVACGAFH 212
Query: 440 SVAL 451
S+AL
Sbjct: 213 SLAL 216
Score = 51.2 bits (117), Expect = 3e-06
Identities = 35/124 (28%), Positives = 56/124 (45%), Gaps = 6/124 (4%)
Frame = +2
Query: 257 TIACGLQHSLAIDEWGQPFSWGSDSMGQLG-NNLGAHAQDKPKFVKG-----LATKNVIQ 418
T+A G HS A+ + G + WG +S GQ N + P + L ++Q
Sbjct: 95 TVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQ 154
Query: 419 VACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNH 598
+ACG H++AL+ S ++++WG Q GL Q + L G + + CG H
Sbjct: 155 LACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLAGRVVLQVACGAFH 212
Query: 599 TFVL 610
+ L
Sbjct: 213 SLAL 216
Score = 39.1 bits (87), Expect = 0.015
Identities = 22/69 (31%), Positives = 36/69 (52%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ G HSLA+ Q +SWGS++ GQLG++ P+ K + V +A G +
Sbjct: 564 LEAGGYHSLALTAKSQVYSWGSNTFGQLGHS--DFPTTVPRLAKISSENGVWSIAAGRDY 621
Query: 440 SVALTNSGD 466
S+ L ++ D
Sbjct: 622 SLFLVDTED 630
Score = 37.1 bits (82), Expect = 0.059
Identities = 22/88 (25%), Positives = 44/88 (50%)
Frame = +2
Query: 377 PKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSL 556
P+ + G K V+Q A G H V LT G++YS+G + +E+ + L+ ++L
Sbjct: 32 PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFGTLPWRSGPVEICPSSPI-LE--NAL 88
Query: 557 IGVPIALITCGNNHTFVLSKSRCGFWMG 640
+G + + G+ H+ ++ + + G
Sbjct: 89 VGQYVITVATGSFHSGAVTDNGVAYMWG 116
Score = 34.7 bits (76), Expect = 0.31
Identities = 16/45 (35%), Positives = 25/45 (55%)
Frame = +3
Query: 54 IKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG 188
++P K + + + AG +HSL L+ +YS G+N GQLG
Sbjct: 548 LQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLG 592
Score = 29.9 bits (64), Expect = 8.9
Identities = 14/41 (34%), Positives = 20/41 (48%)
Frame = +3
Query: 60 PTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQ 182
P L ++ VA G FHS ++++G Y G N GQ
Sbjct: 82 PILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQ 122
>BC040929-1|AAH40929.1| 651|Homo sapiens HERC1 protein protein.
Length = 651
Score = 64.9 bits (151), Expect = 3e-10
Identities = 39/115 (33%), Positives = 65/115 (56%), Gaps = 1/115 (0%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG Q S+A+ + G +++G D + L A ++P+ + LA + VA GA H
Sbjct: 34 VACGTQFSVALTKDGHVYTFGQDRLIGLPEGR-ARNHNRPQQIPVLAGVIIEDVAVGAEH 92
Query: 440 SVALTNSGDLYSWGANSYGQCGL-ELYQTRKCHLQHISSLIGVPIALITCGNNHT 601
++AL ++GD+Y+WG+NS GQ GL R+ L ++ L G + I+ G H+
Sbjct: 93 TLALASNGDVYAWGSNSEGQLGLGHTNHVREPTL--VTGLQGKNVRQISAGRCHS 145
Score = 55.6 bits (128), Expect = 2e-07
Identities = 28/65 (43%), Positives = 39/65 (60%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+A G +H+LA+ G ++WGS+S GQLG H ++ P V GL KNV Q++ G H
Sbjct: 86 VAVGAEHTLALASNGDVYAWGSNSEGQLGLGHTNHVRE-PTLVTGLQGKNVRQISAGRCH 144
Query: 440 SVALT 454
S A T
Sbjct: 145 SAAWT 149
Score = 43.2 bits (97), Expect = 9e-04
Identities = 32/102 (31%), Positives = 49/102 (48%), Gaps = 1/102 (0%)
Frame = +2
Query: 317 WGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYG 496
+G G+LG + A+ P+ + L + +VACG SVALT G +Y++G +
Sbjct: 1 FGDGDYGKLGLG-NSTAKSSPQKIDVLCGIGIKKVACGTQFSVALTKDGHVYTFGQDRL- 58
Query: 497 QCGLELYQTRKCHL-QHISSLIGVPIALITCGNNHTFVLSKS 619
GL + R + Q I L GV I + G HT L+ +
Sbjct: 59 -IGLPEGRARNHNRPQQIPVLAGVIIEDVAVGAEHTLALASN 99
Score = 38.3 bits (85), Expect = 0.026
Identities = 20/56 (35%), Positives = 34/56 (60%)
Frame = +3
Query: 93 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIRQ 260
I+ VA G H+L L+++G +Y+ G+N GQLG +++ + P LV + +RQ
Sbjct: 83 IEDVAVGAEHTLALASNGDVYAWGSNSEGQLG-LGHTNHVREPTLVTGLQGKNVRQ 137
>X97668-1|CAA66258.1| 815|Homo sapiens XLRP3 protein.
Length = 815
Score = 63.3 bits (147), Expect = 8e-10
Identities = 41/115 (35%), Positives = 60/115 (52%), Gaps = 2/115 (1%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKN--VIQVACGAY 436
ACG H+L E G ++ G ++ GQLG LG + V T + Q++ G+
Sbjct: 93 ACGRNHTLVSTEGGNVYATGGNNEGQLG--LGDTEERNTFHVISFFTSEHKIKQLSAGSN 150
Query: 437 HSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHT 601
S ALT G L+ WG NS GQ GL+ + C Q ++ IG P++ I+CG H+
Sbjct: 151 TSAALTEDGRLFMWGDNSEGQIGLK-NVSNVCVPQQVT--IGKPVSWISCGYYHS 202
Score = 60.1 bits (139), Expect = 7e-09
Identities = 36/120 (30%), Positives = 57/120 (47%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
++ G S A+ E G+ F WG +S GQ+G ++ + G K V ++CG YH
Sbjct: 145 LSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVTIG---KPVSWISCGYYH 201
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
S +T G+LY +G G+ GL + S I + + CG HT VL+++
Sbjct: 202 SAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQVACGGEHTVVLTEN 261
Score = 59.7 bits (138), Expect = 1e-08
Identities = 41/129 (31%), Positives = 67/129 (51%), Gaps = 4/129 (3%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAH-AQDKPKFVKGLATKNVIQVACGAY 436
++CG +HS + + + +GS++ GQLG LG+ A KP VK L + V ACG
Sbjct: 40 LSCGDEHSAVVTGNNKLYMFGSNNWGQLG--LGSKSAISKPTCVKALKPEKVKLAACGRN 97
Query: 437 HSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGV--PIALITCGNNHTFVL 610
H++ T G++Y+ G N+ GQ GL T + + H+ S I ++ G+N + L
Sbjct: 98 HTLVSTEGGNVYATGGNNEGQLGLG--DTEERNTFHVISFFTSEHKIKQLSAGSNTSAAL 155
Query: 611 SK-SRCGFW 634
++ R W
Sbjct: 156 TEDGRLFMW 164
Score = 59.7 bits (138), Expect = 1e-08
Identities = 30/124 (24%), Positives = 61/124 (49%), Gaps = 1/124 (0%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG +H++ + E +++G GQLG +PK ++ + + + ++CG H
Sbjct: 248 VACGGEHTVVLTE-NAVYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISCGENH 306
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHI-SSLIGVPIALITCGNNHTFVLSK 616
+ +T+ G +Y++G +G+ GL L + + S+ + + L+ CG H V +
Sbjct: 307 TALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFLRFIVKLVACGGCHMVVFAA 366
Query: 617 SRCG 628
G
Sbjct: 367 PHRG 370
Score = 43.6 bits (98), Expect = 7e-04
Identities = 21/65 (32%), Positives = 35/65 (53%)
Frame = +2
Query: 413 IQVACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGN 592
+ ++CG HS +T + LY +G+N++GQ GL ++ + +L + L CG
Sbjct: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLG-SKSAISKPTCVKALKPEKVKLAACGR 96
Query: 593 NHTFV 607
NHT V
Sbjct: 97 NHTLV 101
Score = 38.3 bits (85), Expect = 0.026
Identities = 19/54 (35%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
Frame = +3
Query: 51 VIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG-RQTESDN 209
+ KPT K + + ++ A G H+L + G++Y+ G N+ GQLG TE N
Sbjct: 75 ISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERN 128
Score = 33.1 bits (72), Expect = 0.96
Identities = 18/56 (32%), Positives = 31/56 (55%)
Frame = +3
Query: 75 WKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFK 242
W ++D ++ G+ HS ++ + LY G+N+ GQLG ++S K P V+ K
Sbjct: 31 WFKNDVPVHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISK-PTCVKALK 85
>U57629-1|AAC50481.1| 815|Homo sapiens retinitis pigmentosa GTPase
regulator protein.
Length = 815
Score = 63.3 bits (147), Expect = 8e-10
Identities = 41/115 (35%), Positives = 60/115 (52%), Gaps = 2/115 (1%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKN--VIQVACGAY 436
ACG H+L E G ++ G ++ GQLG LG + V T + Q++ G+
Sbjct: 93 ACGRNHTLVSTEGGNVYATGGNNEGQLG--LGDTEERNTFHVISFFTSEHKIKQLSAGSN 150
Query: 437 HSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHT 601
S ALT G L+ WG NS GQ GL+ + C Q ++ IG P++ I+CG H+
Sbjct: 151 TSAALTEDGRLFMWGDNSEGQIGLK-NVSNVCVPQQVT--IGKPVSWISCGYYHS 202
Score = 60.1 bits (139), Expect = 7e-09
Identities = 36/120 (30%), Positives = 57/120 (47%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
++ G S A+ E G+ F WG +S GQ+G ++ + G K V ++CG YH
Sbjct: 145 LSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVTIG---KPVSWISCGYYH 201
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
S +T G+LY +G G+ GL + S I + + CG HT VL+++
Sbjct: 202 SAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQVACGGEHTVVLTEN 261
Score = 59.7 bits (138), Expect = 1e-08
Identities = 41/129 (31%), Positives = 67/129 (51%), Gaps = 4/129 (3%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAH-AQDKPKFVKGLATKNVIQVACGAY 436
++CG +HS + + + +GS++ GQLG LG+ A KP VK L + V ACG
Sbjct: 40 LSCGDEHSAVVTGNNKLYMFGSNNWGQLG--LGSKSAISKPTCVKALKPEKVKLAACGRN 97
Query: 437 HSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGV--PIALITCGNNHTFVL 610
H++ T G++Y+ G N+ GQ GL T + + H+ S I ++ G+N + L
Sbjct: 98 HTLVSTEGGNVYATGGNNEGQLGLG--DTEERNTFHVISFFTSEHKIKQLSAGSNTSAAL 155
Query: 611 SK-SRCGFW 634
++ R W
Sbjct: 156 TEDGRLFMW 164
Score = 59.7 bits (138), Expect = 1e-08
Identities = 30/124 (24%), Positives = 61/124 (49%), Gaps = 1/124 (0%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG +H++ + E +++G GQLG +PK ++ + + + ++CG H
Sbjct: 248 VACGGEHTVVLTE-NAVYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISCGENH 306
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHI-SSLIGVPIALITCGNNHTFVLSK 616
+ +T+ G +Y++G +G+ GL L + + S+ + + L+ CG H V +
Sbjct: 307 TALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFLRFIVKLVACGGCHMVVFAA 366
Query: 617 SRCG 628
G
Sbjct: 367 PHRG 370
Score = 43.6 bits (98), Expect = 7e-04
Identities = 21/65 (32%), Positives = 35/65 (53%)
Frame = +2
Query: 413 IQVACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGN 592
+ ++CG HS +T + LY +G+N++GQ GL ++ + +L + L CG
Sbjct: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLG-SKSAISKPTCVKALKPEKVKLAACGR 96
Query: 593 NHTFV 607
NHT V
Sbjct: 97 NHTLV 101
Score = 38.3 bits (85), Expect = 0.026
Identities = 19/54 (35%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
Frame = +3
Query: 51 VIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG-RQTESDN 209
+ KPT K + + ++ A G H+L + G++Y+ G N+ GQLG TE N
Sbjct: 75 ISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERN 128
Score = 33.1 bits (72), Expect = 0.96
Identities = 18/56 (32%), Positives = 31/56 (55%)
Frame = +3
Query: 75 WKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFK 242
W ++D ++ G+ HS ++ + LY G+N+ GQLG ++S K P V+ K
Sbjct: 31 WFKNDVPVHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISK-PTCVKALK 85
>BC031624-1|AAH31624.1| 480|Homo sapiens RPGR protein protein.
Length = 480
Score = 63.3 bits (147), Expect = 8e-10
Identities = 41/115 (35%), Positives = 60/115 (52%), Gaps = 2/115 (1%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKN--VIQVACGAY 436
ACG H+L E G ++ G ++ GQLG LG + V T + Q++ G+
Sbjct: 93 ACGRNHTLVSTEGGNVYATGGNNEGQLG--LGDTEERNTFHVISFFTSEHKIKQLSAGSN 150
Query: 437 HSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHT 601
S ALT G L+ WG NS GQ GL+ + C Q ++ IG P++ I+CG H+
Sbjct: 151 TSAALTEDGRLFMWGDNSEGQIGLK-NVSNVCVPQQVT--IGKPVSWISCGYYHS 202
Score = 60.1 bits (139), Expect = 7e-09
Identities = 36/120 (30%), Positives = 57/120 (47%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
++ G S A+ E G+ F WG +S GQ+G ++ + G K V ++CG YH
Sbjct: 145 LSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVTIG---KPVSWISCGYYH 201
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
S +T G+LY +G G+ GL + S I + + CG HT VL+++
Sbjct: 202 SAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQVACGGEHTVVLTEN 261
Score = 59.7 bits (138), Expect = 1e-08
Identities = 41/129 (31%), Positives = 67/129 (51%), Gaps = 4/129 (3%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAH-AQDKPKFVKGLATKNVIQVACGAY 436
++CG +HS + + + +GS++ GQLG LG+ A KP VK L + V ACG
Sbjct: 40 LSCGDEHSAVVTGNNKLYMFGSNNWGQLG--LGSKSAISKPTCVKALKPEKVKLAACGRN 97
Query: 437 HSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGV--PIALITCGNNHTFVL 610
H++ T G++Y+ G N+ GQ GL T + + H+ S I ++ G+N + L
Sbjct: 98 HTLVSTEGGNVYATGGNNEGQLGLG--DTEERNTFHVISFFTSEHKIKQLSAGSNTSAAL 155
Query: 611 SK-SRCGFW 634
++ R W
Sbjct: 156 TEDGRLFMW 164
Score = 59.7 bits (138), Expect = 1e-08
Identities = 30/124 (24%), Positives = 61/124 (49%), Gaps = 1/124 (0%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG +H++ + E +++G GQLG +PK ++ + + + ++CG H
Sbjct: 248 VACGGEHTVVLTE-NAVYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISCGENH 306
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHI-SSLIGVPIALITCGNNHTFVLSK 616
+ +T+ G +Y++G +G+ GL L + + S+ + + L+ CG H V +
Sbjct: 307 TALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFLRFIVKLVACGGCHMVVFAA 366
Query: 617 SRCG 628
G
Sbjct: 367 PHRG 370
Score = 43.6 bits (98), Expect = 7e-04
Identities = 21/65 (32%), Positives = 35/65 (53%)
Frame = +2
Query: 413 IQVACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGN 592
+ ++CG HS +T + LY +G+N++GQ GL ++ + +L + L CG
Sbjct: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLG-SKSAISKPTCVKALKPEKVKLAACGR 96
Query: 593 NHTFV 607
NHT V
Sbjct: 97 NHTLV 101
Score = 38.3 bits (85), Expect = 0.026
Identities = 19/54 (35%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
Frame = +3
Query: 51 VIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG-RQTESDN 209
+ KPT K + + ++ A G H+L + G++Y+ G N+ GQLG TE N
Sbjct: 75 ISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERN 128
Score = 33.1 bits (72), Expect = 0.96
Identities = 18/56 (32%), Positives = 31/56 (55%)
Frame = +3
Query: 75 WKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFK 242
W ++D ++ G+ HS ++ + LY G+N+ GQLG ++S K P V+ K
Sbjct: 31 WFKNDVPVHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISK-PTCVKALK 85
>BC029174-1|AAH29174.1| 812|Homo sapiens ALS2 protein protein.
Length = 812
Score = 63.3 bits (147), Expect = 8e-10
Identities = 35/85 (41%), Positives = 47/85 (55%)
Frame = +2
Query: 311 FSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANS 490
++WG GQLG+ + +P VK L K VI + G YHS+ALT +YSWG+N+
Sbjct: 529 WTWGKGKEGQLGHG-DVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNT 587
Query: 491 YGQCGLELYQTRKCHLQHISSLIGV 565
+GQ G + T L ISS GV
Sbjct: 588 FGQLGHSDFPTTVPRLAKISSENGV 612
Score = 53.6 bits (123), Expect = 6e-07
Identities = 39/126 (30%), Positives = 59/126 (46%), Gaps = 6/126 (4%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 442
A G++H + + E G+ +S+G+ + P L + VI VA G++HS
Sbjct: 47 ALGVKHGVLLTEDGEVYSFGTLPWRSGPVEI---CPSSPILENALVGQYVITVATGSFHS 103
Query: 443 VALTNSGDLYSWGANSYGQCGL--ELYQTRKCHL----QHISSLIGVPIALITCGNNHTF 604
A+T++G Y G NS GQC + + Y + S L+ V I + CG HT
Sbjct: 104 GAVTDNGVAYMCGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQLACGEEHTL 163
Query: 605 VLSKSR 622
LS SR
Sbjct: 164 ALSISR 169
Score = 52.4 bits (120), Expect = 1e-06
Identities = 28/64 (43%), Positives = 42/64 (65%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG +H+LA+ + ++WG+ QLG A KP+ V+ LA + V+QVACGA+H
Sbjct: 155 LACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLAGRVVLQVACGAFH 212
Query: 440 SVAL 451
S+AL
Sbjct: 213 SLAL 216
Score = 46.0 bits (104), Expect = 1e-04
Identities = 34/124 (27%), Positives = 55/124 (44%), Gaps = 6/124 (4%)
Frame = +2
Query: 257 TIACGLQHSLAIDEWGQPFSWGSDSMGQLG-NNLGAHAQDKPKFVKG-----LATKNVIQ 418
T+A G HS A+ + G + G +S GQ N + P + L ++Q
Sbjct: 95 TVATGSFHSGAVTDNGVAYMCGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQ 154
Query: 419 VACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNH 598
+ACG H++AL+ S ++++WG Q GL Q + L G + + CG H
Sbjct: 155 LACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLAGRVVLQVACGAFH 212
Query: 599 TFVL 610
+ L
Sbjct: 213 SLAL 216
Score = 39.1 bits (87), Expect = 0.015
Identities = 22/69 (31%), Positives = 36/69 (52%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ G HSLA+ Q +SWGS++ GQLG++ P+ K + V +A G +
Sbjct: 564 LEAGGYHSLALTAKSQVYSWGSNTFGQLGHS--DFPTTVPRLAKISSENGVWSIAAGRDY 621
Query: 440 SVALTNSGD 466
S+ L ++ D
Sbjct: 622 SLFLVDTED 630
Score = 37.1 bits (82), Expect = 0.059
Identities = 22/88 (25%), Positives = 44/88 (50%)
Frame = +2
Query: 377 PKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSL 556
P+ + G K V+Q A G H V LT G++YS+G + +E+ + L+ ++L
Sbjct: 32 PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFGTLPWRSGPVEICPSSPI-LE--NAL 88
Query: 557 IGVPIALITCGNNHTFVLSKSRCGFWMG 640
+G + + G+ H+ ++ + + G
Sbjct: 89 VGQYVITVATGSFHSGAVTDNGVAYMCG 116
Score = 34.7 bits (76), Expect = 0.31
Identities = 16/45 (35%), Positives = 25/45 (55%)
Frame = +3
Query: 54 IKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG 188
++P K + + + AG +HSL L+ +YS G+N GQLG
Sbjct: 548 LQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLG 592
Score = 34.3 bits (75), Expect = 0.42
Identities = 15/41 (36%), Positives = 21/41 (51%)
Frame = +3
Query: 60 PTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQ 182
P L ++ VA G FHS ++++G Y CG N GQ
Sbjct: 82 PILENALVGQYVITVATGSFHSGAVTDNGVAYMCGENSAGQ 122
>AL606748-2|CAI95407.1| 815|Homo sapiens retinitis pigmentosa
GTPase regulator protein.
Length = 815
Score = 63.3 bits (147), Expect = 8e-10
Identities = 41/115 (35%), Positives = 60/115 (52%), Gaps = 2/115 (1%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKN--VIQVACGAY 436
ACG H+L E G ++ G ++ GQLG LG + V T + Q++ G+
Sbjct: 93 ACGRNHTLVSTEGGNVYATGGNNEGQLG--LGDTEERNTFHVISFFTSEHKIKQLSAGSN 150
Query: 437 HSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHT 601
S ALT G L+ WG NS GQ GL+ + C Q ++ IG P++ I+CG H+
Sbjct: 151 TSAALTEDGRLFMWGDNSEGQIGLK-NVSNVCVPQQVT--IGKPVSWISCGYYHS 202
Score = 60.1 bits (139), Expect = 7e-09
Identities = 36/120 (30%), Positives = 57/120 (47%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
++ G S A+ E G+ F WG +S GQ+G ++ + G K V ++CG YH
Sbjct: 145 LSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVTIG---KPVSWISCGYYH 201
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
S +T G+LY +G G+ GL + S I + + CG HT VL+++
Sbjct: 202 SAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQVACGGEHTVVLTEN 261
Score = 59.7 bits (138), Expect = 1e-08
Identities = 41/129 (31%), Positives = 67/129 (51%), Gaps = 4/129 (3%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAH-AQDKPKFVKGLATKNVIQVACGAY 436
++CG +HS + + + +GS++ GQLG LG+ A KP VK L + V ACG
Sbjct: 40 LSCGDEHSAVVTGNNKLYMFGSNNWGQLG--LGSKSAISKPTCVKALKPEKVKLAACGRN 97
Query: 437 HSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGV--PIALITCGNNHTFVL 610
H++ T G++Y+ G N+ GQ GL T + + H+ S I ++ G+N + L
Sbjct: 98 HTLVSTEGGNVYATGGNNEGQLGLG--DTEERNTFHVISFFTSEHKIKQLSAGSNTSAAL 155
Query: 611 SK-SRCGFW 634
++ R W
Sbjct: 156 TEDGRLFMW 164
Score = 59.7 bits (138), Expect = 1e-08
Identities = 30/124 (24%), Positives = 61/124 (49%), Gaps = 1/124 (0%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG +H++ + E +++G GQLG +PK ++ + + + ++CG H
Sbjct: 248 VACGGEHTVVLTE-NAVYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISCGENH 306
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHI-SSLIGVPIALITCGNNHTFVLSK 616
+ +T+ G +Y++G +G+ GL L + + S+ + + L+ CG H V +
Sbjct: 307 TALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFLRFIVKLVACGGCHMVVFAA 366
Query: 617 SRCG 628
G
Sbjct: 367 PHRG 370
Score = 43.6 bits (98), Expect = 7e-04
Identities = 21/65 (32%), Positives = 35/65 (53%)
Frame = +2
Query: 413 IQVACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGN 592
+ ++CG HS +T + LY +G+N++GQ GL ++ + +L + L CG
Sbjct: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLG-SKSAISKPTCVKALKPEKVKLAACGR 96
Query: 593 NHTFV 607
NHT V
Sbjct: 97 NHTLV 101
Score = 38.3 bits (85), Expect = 0.026
Identities = 19/54 (35%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
Frame = +3
Query: 51 VIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG-RQTESDN 209
+ KPT K + + ++ A G H+L + G++Y+ G N+ GQLG TE N
Sbjct: 75 ISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERN 128
Score = 33.1 bits (72), Expect = 0.96
Identities = 18/56 (32%), Positives = 31/56 (55%)
Frame = +3
Query: 75 WKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFK 242
W ++D ++ G+ HS ++ + LY G+N+ GQLG ++S K P V+ K
Sbjct: 31 WFKNDVPVHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISK-PTCVKALK 85
>AK223491-1|BAD97211.1| 815|Homo sapiens retinitis pigmentosa
GTPase regulator variant protein.
Length = 815
Score = 63.3 bits (147), Expect = 8e-10
Identities = 41/115 (35%), Positives = 60/115 (52%), Gaps = 2/115 (1%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKN--VIQVACGAY 436
ACG H+L E G ++ G ++ GQLG LG + V T + Q++ G+
Sbjct: 93 ACGRNHTLVSTEGGNVYATGGNNEGQLG--LGDTEERNTFHVISFFTSEHKIKQLSAGSN 150
Query: 437 HSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHT 601
S ALT G L+ WG NS GQ GL+ + C Q ++ IG P++ I+CG H+
Sbjct: 151 TSAALTEDGRLFMWGDNSEGQIGLK-NVSNVCVPQQVT--IGKPVSWISCGYYHS 202
Score = 60.1 bits (139), Expect = 7e-09
Identities = 36/120 (30%), Positives = 57/120 (47%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
++ G S A+ E G+ F WG +S GQ+G ++ + G K V ++CG YH
Sbjct: 145 LSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVTIG---KPVSWISCGYYH 201
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
S +T G+LY +G G+ GL + S I + + CG HT VL+++
Sbjct: 202 SAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQVACGGEHTVVLTEN 261
Score = 59.7 bits (138), Expect = 1e-08
Identities = 41/129 (31%), Positives = 67/129 (51%), Gaps = 4/129 (3%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAH-AQDKPKFVKGLATKNVIQVACGAY 436
++CG +HS + + + +GS++ GQLG LG+ A KP VK L + V ACG
Sbjct: 40 LSCGDEHSAVVTGNNKLYMFGSNNWGQLG--LGSKSAISKPTCVKALKPEKVKLAACGRN 97
Query: 437 HSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGV--PIALITCGNNHTFVL 610
H++ T G++Y+ G N+ GQ GL T + + H+ S I ++ G+N + L
Sbjct: 98 HTLVSTEGGNVYATGGNNEGQLGLG--DTEERNTFHVISFFTSEHKIKQLSAGSNTSAAL 155
Query: 611 SK-SRCGFW 634
++ R W
Sbjct: 156 TEDGRLFMW 164
Score = 59.7 bits (138), Expect = 1e-08
Identities = 30/124 (24%), Positives = 61/124 (49%), Gaps = 1/124 (0%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG +H++ + E +++G GQLG +PK ++ + + + ++CG H
Sbjct: 248 VACGGEHTVVLTE-NAVYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISCGENH 306
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHI-SSLIGVPIALITCGNNHTFVLSK 616
+ +T+ G +Y++G +G+ GL L + + S+ + + L+ CG H V +
Sbjct: 307 TALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFLRFIVKLVACGGCHMVVFAA 366
Query: 617 SRCG 628
G
Sbjct: 367 PHRG 370
Score = 43.6 bits (98), Expect = 7e-04
Identities = 21/65 (32%), Positives = 35/65 (53%)
Frame = +2
Query: 413 IQVACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGN 592
+ ++CG HS +T + LY +G+N++GQ GL ++ + +L + L CG
Sbjct: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLG-SKSAISKPTCVKALKPEKVKLAACGR 96
Query: 593 NHTFV 607
NHT V
Sbjct: 97 NHTLV 101
Score = 38.3 bits (85), Expect = 0.026
Identities = 19/54 (35%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
Frame = +3
Query: 51 VIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG-RQTESDN 209
+ KPT K + + ++ A G H+L + G++Y+ G N+ GQLG TE N
Sbjct: 75 ISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERN 128
Score = 33.1 bits (72), Expect = 0.96
Identities = 18/56 (32%), Positives = 31/56 (55%)
Frame = +3
Query: 75 WKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFK 242
W ++D ++ G+ HS ++ + LY G+N+ GQLG ++S K P V+ K
Sbjct: 31 WFKNDVPVHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISK-PTCVKALK 85
>AJ238395-1|CAB54002.1| 646|Homo sapiens RPGR protein protein.
Length = 646
Score = 63.3 bits (147), Expect = 8e-10
Identities = 41/115 (35%), Positives = 60/115 (52%), Gaps = 2/115 (1%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKN--VIQVACGAY 436
ACG H+L E G ++ G ++ GQLG LG + V T + Q++ G+
Sbjct: 93 ACGRNHTLVSTEGGNVYATGGNNEGQLG--LGDTEERNTFHVISFFTSEHKIKQLSAGSN 150
Query: 437 HSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHT 601
S ALT G L+ WG NS GQ GL+ + C Q ++ IG P++ I+CG H+
Sbjct: 151 TSAALTEDGRLFMWGDNSEGQIGLK-NVSNVCVPQQVT--IGKPVSWISCGYYHS 202
Score = 60.1 bits (139), Expect = 7e-09
Identities = 36/120 (30%), Positives = 57/120 (47%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
++ G S A+ E G+ F WG +S GQ+G ++ + G K V ++CG YH
Sbjct: 145 LSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVTIG---KPVSWISCGYYH 201
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
S +T G+LY +G G+ GL + S I + + CG HT VL+++
Sbjct: 202 SAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQVACGGEHTVVLTEN 261
Score = 59.7 bits (138), Expect = 1e-08
Identities = 41/129 (31%), Positives = 67/129 (51%), Gaps = 4/129 (3%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAH-AQDKPKFVKGLATKNVIQVACGAY 436
++CG +HS + + + +GS++ GQLG LG+ A KP VK L + V ACG
Sbjct: 40 LSCGDEHSAVVTGNNKLYMFGSNNWGQLG--LGSKSAISKPTCVKALKPEKVKLAACGRN 97
Query: 437 HSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGV--PIALITCGNNHTFVL 610
H++ T G++Y+ G N+ GQ GL T + + H+ S I ++ G+N + L
Sbjct: 98 HTLVSTEGGNVYATGGNNEGQLGLG--DTEERNTFHVISFFTSEHKIKQLSAGSNTSAAL 155
Query: 611 SK-SRCGFW 634
++ R W
Sbjct: 156 TEDGRLFMW 164
Score = 59.7 bits (138), Expect = 1e-08
Identities = 30/124 (24%), Positives = 61/124 (49%), Gaps = 1/124 (0%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG +H++ + E +++G GQLG +PK ++ + + + ++CG H
Sbjct: 248 VACGGEHTVVLTE-NAVYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISCGENH 306
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHI-SSLIGVPIALITCGNNHTFVLSK 616
+ +T+ G +Y++G +G+ GL L + + S+ + + L+ CG H V +
Sbjct: 307 TALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFLRFIVKLVACGGCHMVVFAA 366
Query: 617 SRCG 628
G
Sbjct: 367 PHRG 370
Score = 43.6 bits (98), Expect = 7e-04
Identities = 21/65 (32%), Positives = 35/65 (53%)
Frame = +2
Query: 413 IQVACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGN 592
+ ++CG HS +T + LY +G+N++GQ GL ++ + +L + L CG
Sbjct: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLG-SKSAISKPTCVKALKPEKVKLAACGR 96
Query: 593 NHTFV 607
NHT V
Sbjct: 97 NHTLV 101
Score = 38.3 bits (85), Expect = 0.026
Identities = 19/54 (35%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
Frame = +3
Query: 51 VIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG-RQTESDN 209
+ KPT K + + ++ A G H+L + G++Y+ G N+ GQLG TE N
Sbjct: 75 ISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERN 128
Score = 33.1 bits (72), Expect = 0.96
Identities = 18/56 (32%), Positives = 31/56 (55%)
Frame = +3
Query: 75 WKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFK 242
W ++D ++ G+ HS ++ + LY G+N+ GQLG ++S K P V+ K
Sbjct: 31 WFKNDVPVHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISK-PTCVKALK 85
>AF391100-1|AAL14103.1| 1657|Homo sapiens alsin protein.
Length = 1657
Score = 63.3 bits (147), Expect = 8e-10
Identities = 35/85 (41%), Positives = 47/85 (55%)
Frame = +2
Query: 311 FSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANS 490
++WG GQLG+ + +P VK L K VI + G YHS+ALT +YSWG+N+
Sbjct: 529 WTWGKGKEGQLGHG-DVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNT 587
Query: 491 YGQCGLELYQTRKCHLQHISSLIGV 565
+GQ G + T L ISS GV
Sbjct: 588 FGQLGHSDFPTTVPRLAKISSENGV 612
Score = 58.8 bits (136), Expect = 2e-08
Identities = 41/126 (32%), Positives = 62/126 (49%), Gaps = 6/126 (4%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 442
A G++H + + E G+ +S+G+ + + G P L + VI VA G++HS
Sbjct: 47 ALGVKHGVLLTEDGEVYSFGT-LLWRSGPV--EICPSSPILENALVGQYVITVATGSFHS 103
Query: 443 VALTNSGDLYSWGANSYGQCGL--ELYQTRKCHL----QHISSLIGVPIALITCGNNHTF 604
A+T++G Y WG NS GQC + + Y + S L+ V I + CG HT
Sbjct: 104 GAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQLACGEEHTL 163
Query: 605 VLSKSR 622
LS SR
Sbjct: 164 ALSISR 169
Score = 52.4 bits (120), Expect = 1e-06
Identities = 28/64 (43%), Positives = 42/64 (65%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG +H+LA+ + ++WG+ QLG A KP+ V+ LA + V+QVACGA+H
Sbjct: 155 LACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLAGRVVLQVACGAFH 212
Query: 440 SVAL 451
S+AL
Sbjct: 213 SLAL 216
Score = 51.2 bits (117), Expect = 3e-06
Identities = 35/124 (28%), Positives = 56/124 (45%), Gaps = 6/124 (4%)
Frame = +2
Query: 257 TIACGLQHSLAIDEWGQPFSWGSDSMGQLG-NNLGAHAQDKPKFVKG-----LATKNVIQ 418
T+A G HS A+ + G + WG +S GQ N + P + L ++Q
Sbjct: 95 TVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQ 154
Query: 419 VACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNH 598
+ACG H++AL+ S ++++WG Q GL Q + L G + + CG H
Sbjct: 155 LACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLAGRVVLQVACGAFH 212
Query: 599 TFVL 610
+ L
Sbjct: 213 SLAL 216
Score = 39.1 bits (87), Expect = 0.015
Identities = 22/69 (31%), Positives = 36/69 (52%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ G HSLA+ Q +SWGS++ GQLG++ P+ K + V +A G +
Sbjct: 564 LEAGGYHSLALTAKSQVYSWGSNTFGQLGHS--DFPTTVPRLAKISSENGVWSIAAGRDY 621
Query: 440 SVALTNSGD 466
S+ L ++ D
Sbjct: 622 SLFLVDTED 630
Score = 36.7 bits (81), Expect = 0.078
Identities = 22/88 (25%), Positives = 44/88 (50%)
Frame = +2
Query: 377 PKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSL 556
P+ + G K V+Q A G H V LT G++YS+G + +E+ + L+ ++L
Sbjct: 32 PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFGTLLWRSGPVEICPSSPI-LE--NAL 88
Query: 557 IGVPIALITCGNNHTFVLSKSRCGFWMG 640
+G + + G+ H+ ++ + + G
Sbjct: 89 VGQYVITVATGSFHSGAVTDNGVAYMWG 116
Score = 34.7 bits (76), Expect = 0.31
Identities = 16/45 (35%), Positives = 25/45 (55%)
Frame = +3
Query: 54 IKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG 188
++P K + + + AG +HSL L+ +YS G+N GQLG
Sbjct: 548 LQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLG 592
Score = 29.9 bits (64), Expect = 8.9
Identities = 14/41 (34%), Positives = 20/41 (48%)
Frame = +3
Query: 60 PTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQ 182
P L ++ VA G FHS ++++G Y G N GQ
Sbjct: 82 PILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQ 122
>AC007279-1|AAY15058.1| 1598|Homo sapiens unknown protein.
Length = 1598
Score = 63.3 bits (147), Expect = 8e-10
Identities = 35/85 (41%), Positives = 47/85 (55%)
Frame = +2
Query: 311 FSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANS 490
++WG GQLG+ + +P VK L K VI + G YHS+ALT +YSWG+N+
Sbjct: 470 WTWGKGKEGQLGHG-DVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNT 528
Query: 491 YGQCGLELYQTRKCHLQHISSLIGV 565
+GQ G + T L ISS GV
Sbjct: 529 FGQLGHSDFPTTVPRLAKISSENGV 553
Score = 54.4 bits (125), Expect = 4e-07
Identities = 33/88 (37%), Positives = 44/88 (50%), Gaps = 6/88 (6%)
Frame = +2
Query: 377 PKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGL--ELYQTRKCHL---- 538
P L + VI VA G++HS A+T++G Y WG NS GQC + + Y +
Sbjct: 23 PILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIAD 82
Query: 539 QHISSLIGVPIALITCGNNHTFVLSKSR 622
S L+ V I + CG HT LS SR
Sbjct: 83 SEASPLLAVRILQLACGEEHTLALSISR 110
Score = 52.4 bits (120), Expect = 1e-06
Identities = 28/64 (43%), Positives = 42/64 (65%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG +H+LA+ + ++WG+ QLG A KP+ V+ LA + V+QVACGA+H
Sbjct: 96 LACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLAGRVVLQVACGAFH 153
Query: 440 SVAL 451
S+AL
Sbjct: 154 SLAL 157
Score = 51.2 bits (117), Expect = 3e-06
Identities = 35/124 (28%), Positives = 56/124 (45%), Gaps = 6/124 (4%)
Frame = +2
Query: 257 TIACGLQHSLAIDEWGQPFSWGSDSMGQLG-NNLGAHAQDKPKFVKG-----LATKNVIQ 418
T+A G HS A+ + G + WG +S GQ N + P + L ++Q
Sbjct: 36 TVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQ 95
Query: 419 VACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNH 598
+ACG H++AL+ S ++++WG Q GL Q + L G + + CG H
Sbjct: 96 LACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLAGRVVLQVACGAFH 153
Query: 599 TFVL 610
+ L
Sbjct: 154 SLAL 157
Score = 39.1 bits (87), Expect = 0.015
Identities = 22/69 (31%), Positives = 36/69 (52%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ G HSLA+ Q +SWGS++ GQLG++ P+ K + V +A G +
Sbjct: 505 LEAGGYHSLALTAKSQVYSWGSNTFGQLGHS--DFPTTVPRLAKISSENGVWSIAAGRDY 562
Query: 440 SVALTNSGD 466
S+ L ++ D
Sbjct: 563 SLFLVDTED 571
Score = 34.7 bits (76), Expect = 0.31
Identities = 16/45 (35%), Positives = 25/45 (55%)
Frame = +3
Query: 54 IKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG 188
++P K + + + AG +HSL L+ +YS G+N GQLG
Sbjct: 489 LQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLG 533
Score = 29.9 bits (64), Expect = 8.9
Identities = 14/41 (34%), Positives = 20/41 (48%)
Frame = +3
Query: 60 PTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQ 182
P L ++ VA G FHS ++++G Y G N GQ
Sbjct: 23 PILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQ 63
>AB053305-1|BAB69014.1| 1657|Homo sapiens ALS2 protein.
Length = 1657
Score = 63.3 bits (147), Expect = 8e-10
Identities = 35/85 (41%), Positives = 47/85 (55%)
Frame = +2
Query: 311 FSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANS 490
++WG GQLG+ + +P VK L K VI + G YHS+ALT +YSWG+N+
Sbjct: 529 WTWGKGKEGQLGHG-DVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNT 587
Query: 491 YGQCGLELYQTRKCHLQHISSLIGV 565
+GQ G + T L ISS GV
Sbjct: 588 FGQLGHSDFPTTVPRLAKISSENGV 612
Score = 58.8 bits (136), Expect = 2e-08
Identities = 40/126 (31%), Positives = 60/126 (47%), Gaps = 6/126 (4%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 442
A G++H + + E G+ +S+G+ + P L + VI VA G++HS
Sbjct: 47 ALGVKHGVLLTEDGEVYSFGTLPWRSGPVEI---CPSSPILENALVGQYVITVATGSFHS 103
Query: 443 VALTNSGDLYSWGANSYGQCGL--ELYQTRKCHL----QHISSLIGVPIALITCGNNHTF 604
A+T++G Y WG NS GQC + + Y + S L+ V I + CG HT
Sbjct: 104 GAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQLACGEEHTL 163
Query: 605 VLSKSR 622
LS SR
Sbjct: 164 ALSISR 169
Score = 52.4 bits (120), Expect = 1e-06
Identities = 28/64 (43%), Positives = 42/64 (65%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG +H+LA+ + ++WG+ QLG A KP+ V+ LA + V+QVACGA+H
Sbjct: 155 LACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLAGRVVLQVACGAFH 212
Query: 440 SVAL 451
S+AL
Sbjct: 213 SLAL 216
Score = 51.2 bits (117), Expect = 3e-06
Identities = 35/124 (28%), Positives = 56/124 (45%), Gaps = 6/124 (4%)
Frame = +2
Query: 257 TIACGLQHSLAIDEWGQPFSWGSDSMGQLG-NNLGAHAQDKPKFVKG-----LATKNVIQ 418
T+A G HS A+ + G + WG +S GQ N + P + L ++Q
Sbjct: 95 TVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQ 154
Query: 419 VACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNH 598
+ACG H++AL+ S ++++WG Q GL Q + L G + + CG H
Sbjct: 155 LACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLAGRVVLQVACGAFH 212
Query: 599 TFVL 610
+ L
Sbjct: 213 SLAL 216
Score = 39.1 bits (87), Expect = 0.015
Identities = 22/69 (31%), Positives = 36/69 (52%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ G HSLA+ Q +SWGS++ GQLG++ P+ K + V +A G +
Sbjct: 564 LEAGGYHSLALTAKSQVYSWGSNTFGQLGHS--DFPTTVPRLAKISSENGVWSIAAGRDY 621
Query: 440 SVALTNSGD 466
S+ L ++ D
Sbjct: 622 SLFLVDTED 630
Score = 37.1 bits (82), Expect = 0.059
Identities = 22/88 (25%), Positives = 44/88 (50%)
Frame = +2
Query: 377 PKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSL 556
P+ + G K V+Q A G H V LT G++YS+G + +E+ + L+ ++L
Sbjct: 32 PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFGTLPWRSGPVEICPSSPI-LE--NAL 88
Query: 557 IGVPIALITCGNNHTFVLSKSRCGFWMG 640
+G + + G+ H+ ++ + + G
Sbjct: 89 VGQYVITVATGSFHSGAVTDNGVAYMWG 116
Score = 34.7 bits (76), Expect = 0.31
Identities = 16/45 (35%), Positives = 25/45 (55%)
Frame = +3
Query: 54 IKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG 188
++P K + + + AG +HSL L+ +YS G+N GQLG
Sbjct: 548 LQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLG 592
Score = 29.9 bits (64), Expect = 8.9
Identities = 14/41 (34%), Positives = 20/41 (48%)
Frame = +3
Query: 60 PTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQ 182
P L ++ VA G FHS ++++G Y G N GQ
Sbjct: 82 PILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQ 122
>AB046783-1|BAB13389.2| 1658|Homo sapiens KIAA1563 protein protein.
Length = 1658
Score = 63.3 bits (147), Expect = 8e-10
Identities = 35/85 (41%), Positives = 47/85 (55%)
Frame = +2
Query: 311 FSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANS 490
++WG GQLG+ + +P VK L K VI + G YHS+ALT +YSWG+N+
Sbjct: 530 WTWGKGKEGQLGHG-DVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNT 588
Query: 491 YGQCGLELYQTRKCHLQHISSLIGV 565
+GQ G + T L ISS GV
Sbjct: 589 FGQLGHSDFPTTVPRLAKISSENGV 613
Score = 58.8 bits (136), Expect = 2e-08
Identities = 40/126 (31%), Positives = 60/126 (47%), Gaps = 6/126 (4%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 442
A G++H + + E G+ +S+G+ + P L + VI VA G++HS
Sbjct: 48 ALGVKHGVLLTEDGEVYSFGTLPWRSGPVEI---CPSSPILENALVGQYVITVATGSFHS 104
Query: 443 VALTNSGDLYSWGANSYGQCGL--ELYQTRKCHL----QHISSLIGVPIALITCGNNHTF 604
A+T++G Y WG NS GQC + + Y + S L+ V I + CG HT
Sbjct: 105 GAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQLACGEEHTL 164
Query: 605 VLSKSR 622
LS SR
Sbjct: 165 ALSISR 170
Score = 52.4 bits (120), Expect = 1e-06
Identities = 28/64 (43%), Positives = 42/64 (65%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG +H+LA+ + ++WG+ QLG A KP+ V+ LA + V+QVACGA+H
Sbjct: 156 LACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLAGRVVLQVACGAFH 213
Query: 440 SVAL 451
S+AL
Sbjct: 214 SLAL 217
Score = 51.2 bits (117), Expect = 3e-06
Identities = 35/124 (28%), Positives = 56/124 (45%), Gaps = 6/124 (4%)
Frame = +2
Query: 257 TIACGLQHSLAIDEWGQPFSWGSDSMGQLG-NNLGAHAQDKPKFVKG-----LATKNVIQ 418
T+A G HS A+ + G + WG +S GQ N + P + L ++Q
Sbjct: 96 TVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQ 155
Query: 419 VACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNH 598
+ACG H++AL+ S ++++WG Q GL Q + L G + + CG H
Sbjct: 156 LACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLAGRVVLQVACGAFH 213
Query: 599 TFVL 610
+ L
Sbjct: 214 SLAL 217
Score = 39.1 bits (87), Expect = 0.015
Identities = 22/69 (31%), Positives = 36/69 (52%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ G HSLA+ Q +SWGS++ GQLG++ P+ K + V +A G +
Sbjct: 565 LEAGGYHSLALTAKSQVYSWGSNTFGQLGHS--DFPTTVPRLAKISSENGVWSIAAGRDY 622
Query: 440 SVALTNSGD 466
S+ L ++ D
Sbjct: 623 SLFLVDTED 631
Score = 37.1 bits (82), Expect = 0.059
Identities = 22/88 (25%), Positives = 44/88 (50%)
Frame = +2
Query: 377 PKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSL 556
P+ + G K V+Q A G H V LT G++YS+G + +E+ + L+ ++L
Sbjct: 33 PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFGTLPWRSGPVEICPSSPI-LE--NAL 89
Query: 557 IGVPIALITCGNNHTFVLSKSRCGFWMG 640
+G + + G+ H+ ++ + + G
Sbjct: 90 VGQYVITVATGSFHSGAVTDNGVAYMWG 117
Score = 34.7 bits (76), Expect = 0.31
Identities = 16/45 (35%), Positives = 25/45 (55%)
Frame = +3
Query: 54 IKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG 188
++P K + + + AG +HSL L+ +YS G+N GQLG
Sbjct: 549 LQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLG 593
Score = 29.9 bits (64), Expect = 8.9
Identities = 14/41 (34%), Positives = 20/41 (48%)
Frame = +3
Query: 60 PTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQ 182
P L ++ VA G FHS ++++G Y G N GQ
Sbjct: 83 PILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQ 123
>BC112101-1|AAI12102.1| 979|Homo sapiens NIMA related kinase 9
protein.
Length = 979
Score = 62.9 bits (146), Expect = 1e-09
Identities = 36/121 (29%), Positives = 65/121 (53%), Gaps = 1/121 (0%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQD-KPKFVKGLATKNVIQVACGAY 436
++CG ++ + + GQ +++GSD G +G + A + +P + + V QV+CG
Sbjct: 431 VSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDN 490
Query: 437 HSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSK 616
H V LT + ++YSWG YG+ GL+ + Q + + I + CG + TF+L++
Sbjct: 491 HVVVLTRNKEVYSWGCGEYGRLGLDSEEDYYTP-QKVDVPKALIIVAVQCGCDGTFLLTQ 549
Query: 617 S 619
S
Sbjct: 550 S 550
Score = 58.4 bits (135), Expect = 2e-08
Identities = 31/102 (30%), Positives = 59/102 (57%), Gaps = 1/102 (0%)
Frame = +2
Query: 320 GSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQ 499
G+ GQLG+ A + +PK V+ L K + QV+CG +V +T+ G LY++G++ YG
Sbjct: 399 GTKLHGQLGHGDKASYR-QPKHVEKLQGKAIRQVSCGDDFTVCVTDEGQLYAFGSDYYGC 457
Query: 500 CGLE-LYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKSR 622
G++ + ++ + P+ ++CG+NH VL++++
Sbjct: 458 MGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDNHVVVLTRNK 499
Score = 49.6 bits (113), Expect = 1e-05
Identities = 29/86 (33%), Positives = 48/86 (55%), Gaps = 2/86 (2%)
Frame = +2
Query: 257 TIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG--LATKNVIQVACG 430
TIA G H+ AIDE G+ ++G + GQLG +G + + + G L K VI+V+CG
Sbjct: 601 TIAPGKTHTAAIDERGRLLTFGCNKCGQLG--VGNYKKRLGINLLGGPLGGKQVIRVSCG 658
Query: 431 AYHSVALTNSGDLYSWGANSYGQCGL 508
++A T+ +++WG G+ +
Sbjct: 659 DEFTIAATDDNHIFAWGNGGNGRLAM 684
>BC093881-1|AAH93881.1| 979|Homo sapiens NIMA (never in mitosis
gene a)- related kinase 9 protein.
Length = 979
Score = 62.9 bits (146), Expect = 1e-09
Identities = 36/121 (29%), Positives = 65/121 (53%), Gaps = 1/121 (0%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQD-KPKFVKGLATKNVIQVACGAY 436
++CG ++ + + GQ +++GSD G +G + A + +P + + V QV+CG
Sbjct: 431 VSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDN 490
Query: 437 HSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSK 616
H V LT + ++YSWG YG+ GL+ + Q + + I + CG + TF+L++
Sbjct: 491 HVVVLTRNKEVYSWGCGEYGRLGLDSEEDYYTP-QKVDVPKALIIVAVQCGCDGTFLLTQ 549
Query: 617 S 619
S
Sbjct: 550 S 550
Score = 58.4 bits (135), Expect = 2e-08
Identities = 31/102 (30%), Positives = 59/102 (57%), Gaps = 1/102 (0%)
Frame = +2
Query: 320 GSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQ 499
G+ GQLG+ A + +PK V+ L K + QV+CG +V +T+ G LY++G++ YG
Sbjct: 399 GTKLHGQLGHGDKASYR-QPKHVEKLQGKAIRQVSCGDDFTVCVTDEGQLYAFGSDYYGC 457
Query: 500 CGLE-LYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKSR 622
G++ + ++ + P+ ++CG+NH VL++++
Sbjct: 458 MGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDNHVVVLTRNK 499
Score = 49.6 bits (113), Expect = 1e-05
Identities = 29/86 (33%), Positives = 48/86 (55%), Gaps = 2/86 (2%)
Frame = +2
Query: 257 TIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG--LATKNVIQVACG 430
TIA G H+ AIDE G+ ++G + GQLG +G + + + G L K VI+V+CG
Sbjct: 601 TIAPGKTHTAAIDERGRLLTFGCNKCGQLG--VGNYKKRLGINLLGGPLGGKQVIRVSCG 658
Query: 431 AYHSVALTNSGDLYSWGANSYGQCGL 508
++A T+ +++WG G+ +
Sbjct: 659 DEFTIAATDDNHIFAWGNGGNGRLAM 684
>AY080896-1|AAL87410.1| 979|Homo sapiens NIMA-family kinase NERCC1
protein.
Length = 979
Score = 62.9 bits (146), Expect = 1e-09
Identities = 36/121 (29%), Positives = 65/121 (53%), Gaps = 1/121 (0%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQD-KPKFVKGLATKNVIQVACGAY 436
++CG ++ + + GQ +++GSD G +G + A + +P + + V QV+CG
Sbjct: 431 VSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDN 490
Query: 437 HSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSK 616
H V LT + ++YSWG YG+ GL+ + Q + + I + CG + TF+L++
Sbjct: 491 HVVVLTRNKEVYSWGCGEYGRLGLDSEEDYYTP-QKVDVPKALIIVAVQCGCDGTFLLTQ 549
Query: 617 S 619
S
Sbjct: 550 S 550
Score = 58.4 bits (135), Expect = 2e-08
Identities = 31/102 (30%), Positives = 59/102 (57%), Gaps = 1/102 (0%)
Frame = +2
Query: 320 GSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQ 499
G+ GQLG+ A + +PK V+ L K + QV+CG +V +T+ G LY++G++ YG
Sbjct: 399 GTKLHGQLGHGDKASYR-QPKHVEKLQGKAIHQVSCGDDFTVCVTDEGQLYAFGSDYYGC 457
Query: 500 CGLE-LYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKSR 622
G++ + ++ + P+ ++CG+NH VL++++
Sbjct: 458 MGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDNHVVVLTRNK 499
Score = 49.6 bits (113), Expect = 1e-05
Identities = 29/86 (33%), Positives = 48/86 (55%), Gaps = 2/86 (2%)
Frame = +2
Query: 257 TIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG--LATKNVIQVACG 430
TIA G H+ AIDE G+ ++G + GQLG +G + + + G L K VI+V+CG
Sbjct: 601 TIAPGKTHTAAIDERGRLLTFGCNKCGQLG--VGNYKKRLGINLLGGPLGGKQVIRVSCG 658
Query: 431 AYHSVALTNSGDLYSWGANSYGQCGL 508
++A T+ +++WG G+ +
Sbjct: 659 DEFTIAATDDNHIFAWGNGGNGRLAM 684
>AY048580-1|AAL05428.1| 979|Homo sapiens NIMA-related kinase Nek8
protein.
Length = 979
Score = 62.9 bits (146), Expect = 1e-09
Identities = 36/121 (29%), Positives = 65/121 (53%), Gaps = 1/121 (0%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQD-KPKFVKGLATKNVIQVACGAY 436
++CG ++ + + GQ +++GSD G +G + A + +P + + V QV+CG
Sbjct: 431 VSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDN 490
Query: 437 HSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSK 616
H V LT + ++YSWG YG+ GL+ + Q + + I + CG + TF+L++
Sbjct: 491 HVVVLTRNKEVYSWGCGEYGRLGLDSEEDYYTP-QKVDVPKALIIVAVQCGCDGTFLLTQ 549
Query: 617 S 619
S
Sbjct: 550 S 550
Score = 58.4 bits (135), Expect = 2e-08
Identities = 31/102 (30%), Positives = 59/102 (57%), Gaps = 1/102 (0%)
Frame = +2
Query: 320 GSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQ 499
G+ GQLG+ A + +PK V+ L K + QV+CG +V +T+ G LY++G++ YG
Sbjct: 399 GTKLHGQLGHGDKASYR-QPKHVEKLQGKAIHQVSCGDDFTVCVTDEGQLYAFGSDYYGC 457
Query: 500 CGLE-LYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKSR 622
G++ + ++ + P+ ++CG+NH VL++++
Sbjct: 458 MGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDNHVVVLTRNK 499
Score = 49.6 bits (113), Expect = 1e-05
Identities = 29/86 (33%), Positives = 48/86 (55%), Gaps = 2/86 (2%)
Frame = +2
Query: 257 TIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG--LATKNVIQVACG 430
TIA G H+ AIDE G+ ++G + GQLG +G + + + G L K VI+V+CG
Sbjct: 601 TIAPGKTHTAAIDERGRLLTFGCNKCGQLG--VGNYKKRLGINLLGGPLGGKQVIRVSCG 658
Query: 431 AYHSVALTNSGDLYSWGANSYGQCGL 508
++A T+ +++WG G+ +
Sbjct: 659 DEFTIAATDDNHIFAWGNGGNGRLAM 684
>AJ318463-1|CAC86116.1| 815|Homo sapiens retinitis pigmentosa
GTPase regulator protein.
Length = 815
Score = 62.9 bits (146), Expect = 1e-09
Identities = 41/115 (35%), Positives = 60/115 (52%), Gaps = 2/115 (1%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKN--VIQVACGAY 436
ACG H+L E G ++ G ++ GQLG LG + V T + Q++ G+
Sbjct: 93 ACGRNHTLVSTEGGNVYATGGNNEGQLG--LGDTEERNTFHVISFFTSEHKIKQLSAGSN 150
Query: 437 HSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHT 601
S ALT G L+ WG NS GQ GL+ + C Q ++ IG P++ I+CG H+
Sbjct: 151 TSAALTEDGRLFMWGDNSEGQIGLK-NVSNVCVPQQVT--IGNPVSWISCGYYHS 202
Score = 59.7 bits (138), Expect = 1e-08
Identities = 41/129 (31%), Positives = 67/129 (51%), Gaps = 4/129 (3%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAH-AQDKPKFVKGLATKNVIQVACGAY 436
++CG +HS + + + +GS++ GQLG LG+ A KP VK L + V ACG
Sbjct: 40 LSCGDEHSAVVTGNNKLYMFGSNNWGQLG--LGSKSAISKPTCVKALKPEKVKLAACGRN 97
Query: 437 HSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGV--PIALITCGNNHTFVL 610
H++ T G++Y+ G N+ GQ GL T + + H+ S I ++ G+N + L
Sbjct: 98 HTLVSTEGGNVYATGGNNEGQLGLG--DTEERNTFHVISFFTSEHKIKQLSAGSNTSAAL 155
Query: 611 SK-SRCGFW 634
++ R W
Sbjct: 156 TEDGRLFMW 164
Score = 59.7 bits (138), Expect = 1e-08
Identities = 30/124 (24%), Positives = 61/124 (49%), Gaps = 1/124 (0%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG +H++ + E +++G GQLG +PK ++ + + + ++CG H
Sbjct: 248 VACGGEHTVVLTE-NAVYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISCGENH 306
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHI-SSLIGVPIALITCGNNHTFVLSK 616
+ +T+ G +Y++G +G+ GL L + + S+ + + L+ CG H V +
Sbjct: 307 TALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFLRFIVKLVACGGCHMVVFAA 366
Query: 617 SRCG 628
G
Sbjct: 367 PHRG 370
Score = 58.0 bits (134), Expect = 3e-08
Identities = 35/120 (29%), Positives = 56/120 (46%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
++ G S A+ E G+ F WG +S GQ+G ++ + G V ++CG YH
Sbjct: 145 LSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVTIG---NPVSWISCGYYH 201
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
S +T G+LY +G G+ GL + S I + + CG HT VL+++
Sbjct: 202 SAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQVACGGEHTVVLTEN 261
Score = 43.6 bits (98), Expect = 7e-04
Identities = 21/65 (32%), Positives = 35/65 (53%)
Frame = +2
Query: 413 IQVACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGN 592
+ ++CG HS +T + LY +G+N++GQ GL ++ + +L + L CG
Sbjct: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLG-SKSAISKPTCVKALKPEKVKLAACGR 96
Query: 593 NHTFV 607
NHT V
Sbjct: 97 NHTLV 101
Score = 38.3 bits (85), Expect = 0.026
Identities = 19/54 (35%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
Frame = +3
Query: 51 VIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG-RQTESDN 209
+ KPT K + + ++ A G H+L + G++Y+ G N+ GQLG TE N
Sbjct: 75 ISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERN 128
Score = 33.1 bits (72), Expect = 0.96
Identities = 18/56 (32%), Positives = 31/56 (55%)
Frame = +3
Query: 75 WKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFK 242
W ++D ++ G+ HS ++ + LY G+N+ GQLG ++S K P V+ K
Sbjct: 31 WFKNDVPVHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISK-PTCVKALK 85
>AC007055-4|AAD31939.1| 414|Homo sapiens protein ( Homo sapiens
chromosome 14 clone BAC 201F1 map 14q24.3, complete
sequence. ).
Length = 414
Score = 62.9 bits (146), Expect = 1e-09
Identities = 36/121 (29%), Positives = 65/121 (53%), Gaps = 1/121 (0%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQD-KPKFVKGLATKNVIQVACGAY 436
++CG ++ + + GQ +++GSD G +G + A + +P + + V QV+CG
Sbjct: 101 VSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDN 160
Query: 437 HSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSK 616
H V LT + ++YSWG YG+ GL+ + Q + + I + CG + TF+L++
Sbjct: 161 HVVVLTRNKEVYSWGCGEYGRLGLDSEEDYYTP-QKVDVPKALIIVAVQCGCDGTFLLTQ 219
Query: 617 S 619
S
Sbjct: 220 S 220
Score = 58.4 bits (135), Expect = 2e-08
Identities = 31/102 (30%), Positives = 59/102 (57%), Gaps = 1/102 (0%)
Frame = +2
Query: 320 GSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQ 499
G+ GQLG+ A + +PK V+ L K + QV+CG +V +T+ G LY++G++ YG
Sbjct: 69 GTKLHGQLGHGDKASYR-QPKHVEKLQGKAIRQVSCGDDFTVCVTDEGQLYAFGSDYYGC 127
Query: 500 CGLE-LYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKSR 622
G++ + ++ + P+ ++CG+NH VL++++
Sbjct: 128 MGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDNHVVVLTRNK 169
Score = 49.6 bits (113), Expect = 1e-05
Identities = 29/86 (33%), Positives = 48/86 (55%), Gaps = 2/86 (2%)
Frame = +2
Query: 257 TIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG--LATKNVIQVACG 430
TIA G H+ AIDE G+ ++G + GQLG +G + + + G L K VI+V+CG
Sbjct: 271 TIAPGKTHTAAIDERGRLLTFGCNKCGQLG--VGNYKKRLGINLLGGPLGGKQVIRVSCG 328
Query: 431 AYHSVALTNSGDLYSWGANSYGQCGL 508
++A T+ +++WG G+ +
Sbjct: 329 DEFTIAATDDNHIFAWGNGGNGRLAM 354
>AB082526-1|BAC02704.1| 1011|Homo sapiens KIAA1995 protein protein.
Length = 1011
Score = 62.9 bits (146), Expect = 1e-09
Identities = 36/121 (29%), Positives = 65/121 (53%), Gaps = 1/121 (0%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQD-KPKFVKGLATKNVIQVACGAY 436
++CG ++ + + GQ +++GSD G +G + A + +P + + V QV+CG
Sbjct: 463 VSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDN 522
Query: 437 HSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSK 616
H V LT + ++YSWG YG+ GL+ + Q + + I + CG + TF+L++
Sbjct: 523 HVVVLTRNKEVYSWGCGEYGRLGLDSEEDYYTP-QKVDVPKALIIVAVQCGCDGTFLLTQ 581
Query: 617 S 619
S
Sbjct: 582 S 582
Score = 58.4 bits (135), Expect = 2e-08
Identities = 31/102 (30%), Positives = 59/102 (57%), Gaps = 1/102 (0%)
Frame = +2
Query: 320 GSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQ 499
G+ GQLG+ A + +PK V+ L K + QV+CG +V +T+ G LY++G++ YG
Sbjct: 431 GTKLHGQLGHGDKASYR-QPKHVEKLQGKAIHQVSCGDDFTVCVTDEGQLYAFGSDYYGC 489
Query: 500 CGLE-LYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKSR 622
G++ + ++ + P+ ++CG+NH VL++++
Sbjct: 490 MGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDNHVVVLTRNK 531
Score = 49.6 bits (113), Expect = 1e-05
Identities = 29/86 (33%), Positives = 48/86 (55%), Gaps = 2/86 (2%)
Frame = +2
Query: 257 TIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG--LATKNVIQVACG 430
TIA G H+ AIDE G+ ++G + GQLG +G + + + G L K VI+V+CG
Sbjct: 633 TIAPGKTHTAAIDERGRLLTFGCNKCGQLG--VGNYKKRLGINLLGGPLGGKQVIRVSCG 690
Query: 431 AYHSVALTNSGDLYSWGANSYGQCGL 508
++A T+ +++WG G+ +
Sbjct: 691 DEFTIAATDDNHIFAWGNGGNGRLAM 716
>BC004933-1|AAH04933.1| 351|Homo sapiens RCC2 protein protein.
Length = 351
Score = 61.3 bits (142), Expect = 3e-09
Identities = 31/100 (31%), Positives = 53/100 (53%)
Frame = +2
Query: 311 FSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANS 490
+SWG + GQLG+ + P+ ++GL+ + ++ ACG H++ALT +G ++++G N
Sbjct: 1 WSWGRNEKGQLGHG-DTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENK 59
Query: 491 YGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVL 610
GQ GL QT G PI + CG + ++
Sbjct: 60 MGQLGLG-NQTDAVPSPAQIMYNGQPITKMACGAEFSMIM 98
Score = 60.1 bits (139), Expect = 7e-09
Identities = 31/81 (38%), Positives = 45/81 (55%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 442
ACG H+LA+ E G F++G + MGQLG A P + + + ++ACGA S
Sbjct: 37 ACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQIM-YNGQPITKMACGAEFS 95
Query: 443 VALTNSGDLYSWGANSYGQCG 505
+ + G+LYS+G YGQ G
Sbjct: 96 MIMDCKGNLYSFGCPEYGQLG 116
Score = 46.8 bits (106), Expect = 7e-05
Identities = 27/81 (33%), Positives = 42/81 (51%), Gaps = 4/81 (4%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK--PKFVK--GLATKNVIQVAC 427
+ACG H+L +D + FSWG G+LG+ A +D+ P+ VK + Q+
Sbjct: 164 VACGANHTLVLDSQKRVFSWGFGGYGRLGH---AEQKDEMVPRLVKLFDFPGRGASQIYA 220
Query: 428 GAYHSVALTNSGDLYSWGANS 490
G S A++ G L+ WGA +
Sbjct: 221 GYTCSFAVSEVGGLFFWGATN 241
Score = 45.2 bits (102), Expect = 2e-04
Identities = 35/107 (32%), Positives = 51/107 (47%), Gaps = 23/107 (21%)
Frame = +2
Query: 254 TTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLG----AHAQ----------------- 370
T +ACG + S+ +D G +S+G GQLG+N A AQ
Sbjct: 86 TKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFI 145
Query: 371 DKPKFVKGLATKNVI--QVACGAYHSVALTNSGDLYSWGANSYGQCG 505
+K K + L NV+ VACGA H++ L + ++SWG YG+ G
Sbjct: 146 EKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYGRLG 192
Score = 38.3 bits (85), Expect = 0.026
Identities = 20/63 (31%), Positives = 34/63 (53%)
Frame = +3
Query: 42 TDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNP 221
T V P L + + I + A G H+L L+ +G +++ G N +GQLG ++D +P
Sbjct: 16 TKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSP 75
Query: 222 ALV 230
A +
Sbjct: 76 AQI 78
Score = 29.9 bits (64), Expect = 8.9
Identities = 19/58 (32%), Positives = 25/58 (43%), Gaps = 1/58 (1%)
Frame = +2
Query: 470 YSWGANSYGQCGLELYQTRKCHLQH-ISSLIGVPIALITCGNNHTFVLSKSRCGFWMG 640
+SWG N GQ G T++ I L I CG NHT L+++ F G
Sbjct: 1 WSWGRNEKGQLGHG--DTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFG 56
>BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis
gene a)- related kinase 8 protein.
Length = 692
Score = 59.7 bits (138), Expect = 1e-08
Identities = 34/118 (28%), Positives = 59/118 (50%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG + + + G ++GS S G LG+ +P V+ L ++QVACGA H
Sbjct: 396 VACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDIS-QPTIVEALLGYEMVQVACGASH 454
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
+AL+ +L++WG G+ GL ++ C Q + G + CG + + +L+
Sbjct: 455 VLALSTERELFAWGRGDSGRLGLGTRESHSCP-QQVPMPPGQEAQRVVCGIDSSMILT 511
Score = 53.6 bits (123), Expect = 6e-07
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +2
Query: 257 TIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAY 436
+I G HS A+ G +++GS+ GQLG N ++ P V+GL + VACG
Sbjct: 565 SIDLGTAHSAAVTASGDCYTFGSNQHGQLGTNTRRGSR-APCKVQGLEGIKMAMVACGDA 623
Query: 437 HSVALTNSGDLYSWGANSYGQCG 505
+VA+ ++YSWG + G+ G
Sbjct: 624 FTVAIGAESEVYSWGKGARGRLG 646
Score = 50.0 bits (114), Expect = 8e-06
Identities = 32/130 (24%), Positives = 62/130 (47%), Gaps = 13/130 (10%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNN---LGAHAQDKPKFVKGLA---------- 400
+ CG+ S+ + GQ + GS+ +LG + LG + + L+
Sbjct: 500 VVCGIDSSMILTVPGQALACGSNRFNKLGLDHLSLGEEPVPHQQVEEALSFTLLGSAPLD 559
Query: 401 TKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALI 580
+ ++ + G HS A+T SGD Y++G+N +GQ G + + + + L G+ +A++
Sbjct: 560 QEPLLSIDLGTAHSAAVTASGDCYTFGSNQHGQLGTNTRRGSRAPCK-VQGLEGIKMAMV 618
Query: 581 TCGNNHTFVL 610
CG+ T +
Sbjct: 619 ACGDAFTVAI 628
Score = 48.8 bits (111), Expect = 2e-05
Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 6/127 (4%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNL--GAHAQDKPKFV----KGLATKNVIQV 421
+A G + G+ W + +G G +L GA Q +P+F+ +G + + V
Sbjct: 337 VAAGRTQKAGVTRSGRLILWEAPPLGAGGGSLLPGAVEQPQPQFISRFLEGQSGVTIKHV 396
Query: 422 ACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHT 601
ACG + + LT+ G + ++G+ S G G T + +L+G + + CG +H
Sbjct: 397 ACGDFFTACLTDRGIIMTFGSGSNGCLGHGSL-TDISQPTIVEALLGYEMVQVACGASHV 455
Query: 602 FVLSKSR 622
LS R
Sbjct: 456 LALSTER 462
Score = 45.6 bits (103), Expect = 2e-04
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 1/85 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK-PKFVKGLATKNVIQVACGAY 436
+ACG H LA+ + F+WG G+LG LG P+ V + +V CG
Sbjct: 448 VACGASHVLALSTERELFAWGRGDSGRLG--LGTRESHSCPQQVPMPPGQEAQRVVCGID 505
Query: 437 HSVALTNSGDLYSWGANSYGQCGLE 511
S+ LT G + G+N + + GL+
Sbjct: 506 SSMILTVPGQALACGSNRFNKLGLD 530
Score = 29.9 bits (64), Expect = 8.9
Identities = 13/39 (33%), Positives = 22/39 (56%)
Frame = +3
Query: 81 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQT 197
+ + + ++ G HS ++ SG Y+ G+N GQLG T
Sbjct: 559 DQEPLLSIDLGTAHSAAVTASGDCYTFGSNQHGQLGTNT 597
>BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8
protein.
Length = 692
Score = 59.7 bits (138), Expect = 1e-08
Identities = 34/118 (28%), Positives = 59/118 (50%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG + + + G ++GS S G LG+ +P V+ L ++QVACGA H
Sbjct: 396 VACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDIS-QPTIVEALLGYEMVQVACGASH 454
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
+AL+ +L++WG G+ GL ++ C Q + G + CG + + +L+
Sbjct: 455 VLALSTERELFAWGRGDSGRLGLGTRESHSCP-QQVPMPPGQEAQRVVCGIDSSMILT 511
Score = 53.6 bits (123), Expect = 6e-07
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +2
Query: 257 TIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAY 436
+I G HS A+ G +++GS+ GQLG N ++ P V+GL + VACG
Sbjct: 565 SIDLGTAHSAAVTASGDCYTFGSNQHGQLGTNTRRGSR-APCKVQGLEGIKMAMVACGDA 623
Query: 437 HSVALTNSGDLYSWGANSYGQCG 505
+VA+ ++YSWG + G+ G
Sbjct: 624 FTVAIGAESEVYSWGKGARGRLG 646
Score = 50.0 bits (114), Expect = 8e-06
Identities = 32/130 (24%), Positives = 62/130 (47%), Gaps = 13/130 (10%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNN---LGAHAQDKPKFVKGLA---------- 400
+ CG+ S+ + GQ + GS+ +LG + LG + + L+
Sbjct: 500 VVCGIDSSMILTVPGQALACGSNRFNKLGLDHLSLGEEPVPHQQVEEALSFTLLGSAPLD 559
Query: 401 TKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALI 580
+ ++ + G HS A+T SGD Y++G+N +GQ G + + + + L G+ +A++
Sbjct: 560 QEPLLSIDLGTAHSAAVTASGDCYTFGSNQHGQLGTNTRRGSRAPCK-VQGLEGIKMAMV 618
Query: 581 TCGNNHTFVL 610
CG+ T +
Sbjct: 619 ACGDAFTVAI 628
Score = 48.8 bits (111), Expect = 2e-05
Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 6/127 (4%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNL--GAHAQDKPKFV----KGLATKNVIQV 421
+A G + G+ W + +G G +L GA Q +P+F+ +G + + V
Sbjct: 337 VAAGRTQKAGVTRSGRLILWEAPPLGAGGGSLLPGAVEQPQPQFISRFLEGQSGVTIKHV 396
Query: 422 ACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHT 601
ACG + + LT+ G + ++G+ S G G T + +L+G + + CG +H
Sbjct: 397 ACGDFFTACLTDRGIIMTFGSGSNGCLGHGSL-TDISQPTIVEALLGYEMVQVACGASHV 455
Query: 602 FVLSKSR 622
LS R
Sbjct: 456 LALSTER 462
Score = 45.6 bits (103), Expect = 2e-04
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 1/85 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK-PKFVKGLATKNVIQVACGAY 436
+ACG H LA+ + F+WG G+LG LG P+ V + +V CG
Sbjct: 448 VACGASHVLALSTERELFAWGRGDSGRLG--LGTRESHSCPQQVPMPPGQEAQRVVCGID 505
Query: 437 HSVALTNSGDLYSWGANSYGQCGLE 511
S+ LT G + G+N + + GL+
Sbjct: 506 SSMILTVPGQALACGSNRFNKLGLD 530
Score = 29.9 bits (64), Expect = 8.9
Identities = 13/39 (33%), Positives = 22/39 (56%)
Frame = +3
Query: 81 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQT 197
+ + + ++ G HS ++ SG Y+ G+N GQLG T
Sbjct: 559 DQEPLLSIDLGTAHSAAVTASGDCYTFGSNQHGQLGTNT 597
>AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8
protein.
Length = 692
Score = 59.7 bits (138), Expect = 1e-08
Identities = 34/118 (28%), Positives = 59/118 (50%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG + + + G ++GS S G LG+ +P V+ L ++QVACGA H
Sbjct: 396 VACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDIS-QPTIVEALLGYEMVQVACGASH 454
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
+AL+ +L++WG G+ GL ++ C Q + G + CG + + +L+
Sbjct: 455 VLALSTERELFAWGRGDSGRLGLGTRESHSCP-QQVPMPPGQEAQRVVCGIDSSMILT 511
Score = 53.6 bits (123), Expect = 6e-07
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +2
Query: 257 TIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAY 436
+I G HS A+ G +++GS+ GQLG N ++ P V+GL + VACG
Sbjct: 565 SIDLGTAHSAAVTASGDCYTFGSNQHGQLGTNTRRGSR-APCKVQGLEGIKMAMVACGDA 623
Query: 437 HSVALTNSGDLYSWGANSYGQCG 505
+VA+ ++YSWG + G+ G
Sbjct: 624 FTVAIGAESEVYSWGKGARGRLG 646
Score = 50.0 bits (114), Expect = 8e-06
Identities = 32/130 (24%), Positives = 62/130 (47%), Gaps = 13/130 (10%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNN---LGAHAQDKPKFVKGLA---------- 400
+ CG+ S+ + GQ + GS+ +LG + LG + + L+
Sbjct: 500 VVCGIDSSMILTVPGQALACGSNRFNKLGLDHLSLGEEPVPHQQVEEALSFTLLGSAPLD 559
Query: 401 TKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALI 580
+ ++ + G HS A+T SGD Y++G+N +GQ G + + + + L G+ +A++
Sbjct: 560 QEPLLSIDLGTAHSAAVTASGDCYTFGSNQHGQLGTNTRRGSRAPCK-VQGLEGIKMAMV 618
Query: 581 TCGNNHTFVL 610
CG+ T +
Sbjct: 619 ACGDAFTVAI 628
Score = 48.8 bits (111), Expect = 2e-05
Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 6/127 (4%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNL--GAHAQDKPKFV----KGLATKNVIQV 421
+A G + G+ W + +G G +L GA Q +P+F+ +G + + V
Sbjct: 337 VAAGRTQKAGVTRSGRLILWEAPPLGAGGGSLLPGAVEQPQPQFISRFLEGQSGVTIKHV 396
Query: 422 ACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHT 601
ACG + + LT+ G + ++G+ S G G T + +L+G + + CG +H
Sbjct: 397 ACGDFFTACLTDRGIIMTFGSGSNGCLGHGSL-TDISQPTIVEALLGYEMVQVACGASHV 455
Query: 602 FVLSKSR 622
LS R
Sbjct: 456 LALSTER 462
Score = 45.6 bits (103), Expect = 2e-04
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 1/85 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK-PKFVKGLATKNVIQVACGAY 436
+ACG H LA+ + F+WG G+LG LG P+ V + +V CG
Sbjct: 448 VACGASHVLALSTERELFAWGRGDSGRLG--LGTRESHSCPQQVPMPPGQEAQRVVCGID 505
Query: 437 HSVALTNSGDLYSWGANSYGQCGLE 511
S+ LT G + G+N + + GL+
Sbjct: 506 SSMILTVPGQALACGSNRFNKLGLD 530
Score = 29.9 bits (64), Expect = 8.9
Identities = 13/39 (33%), Positives = 22/39 (56%)
Frame = +3
Query: 81 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQT 197
+ + + ++ G HS ++ SG Y+ G+N GQLG T
Sbjct: 559 DQEPLLSIDLGTAHSAAVTASGDCYTFGSNQHGQLGTNT 597
>AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a
protein.
Length = 692
Score = 59.7 bits (138), Expect = 1e-08
Identities = 34/118 (28%), Positives = 59/118 (50%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG + + + G ++GS S G LG+ +P V+ L ++QVACGA H
Sbjct: 396 VACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDIS-QPTIVEALLGYEMVQVACGASH 454
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
+AL+ +L++WG G+ GL ++ C Q + G + CG + + +L+
Sbjct: 455 VLALSTERELFAWGRGDSGRLGLGTRESHSCP-QQVPMPPGQEAQRVVCGIDSSMILT 511
Score = 53.6 bits (123), Expect = 6e-07
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +2
Query: 257 TIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAY 436
+I G HS A+ G +++GS+ GQLG N ++ P V+GL + VACG
Sbjct: 565 SIDLGTAHSAAVTASGDCYTFGSNQHGQLGTNTRRGSR-APCKVQGLEGIKMAMVACGDA 623
Query: 437 HSVALTNSGDLYSWGANSYGQCG 505
+VA+ ++YSWG + G+ G
Sbjct: 624 FTVAIGAESEVYSWGKGARGRLG 646
Score = 50.0 bits (114), Expect = 8e-06
Identities = 32/130 (24%), Positives = 62/130 (47%), Gaps = 13/130 (10%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNN---LGAHAQDKPKFVKGLA---------- 400
+ CG+ S+ + GQ + GS+ +LG + LG + + L+
Sbjct: 500 VVCGIDSSMILTVPGQALACGSNRFNKLGLDHLSLGEEPVPHQQVEEALSFTLLGSAPLD 559
Query: 401 TKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALI 580
+ ++ + G HS A+T SGD Y++G+N +GQ G + + + + L G+ +A++
Sbjct: 560 QEPLLSIDLGTAHSAAVTASGDCYTFGSNQHGQLGTNTRRGSRAPCK-VQGLEGIKMAMV 618
Query: 581 TCGNNHTFVL 610
CG+ T +
Sbjct: 619 ACGDAFTVAI 628
Score = 48.8 bits (111), Expect = 2e-05
Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 6/127 (4%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNL--GAHAQDKPKFV----KGLATKNVIQV 421
+A G + G+ W + +G G +L GA Q +P+F+ +G + + V
Sbjct: 337 VAAGRTQKAGVTRSGRLILWEAPPLGAGGGSLLPGAVEQPQPQFISRFLEGQSGVTIKHV 396
Query: 422 ACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHT 601
ACG + + LT+ G + ++G+ S G G T + +L+G + + CG +H
Sbjct: 397 ACGDFFTACLTDRGIIMTFGSGSNGCLGHGSL-TDISQPTIVEALLGYEMVQVACGASHV 455
Query: 602 FVLSKSR 622
LS R
Sbjct: 456 LALSTER 462
Score = 45.6 bits (103), Expect = 2e-04
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 1/85 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK-PKFVKGLATKNVIQVACGAY 436
+ACG H LA+ + F+WG G+LG LG P+ V + +V CG
Sbjct: 448 VACGASHVLALSTERELFAWGRGDSGRLG--LGTRESHSCPQQVPMPPGQEAQRVVCGID 505
Query: 437 HSVALTNSGDLYSWGANSYGQCGLE 511
S+ LT G + G+N + + GL+
Sbjct: 506 SSMILTVPGQALACGSNRFNKLGLD 530
Score = 29.9 bits (64), Expect = 8.9
Identities = 13/39 (33%), Positives = 22/39 (56%)
Frame = +3
Query: 81 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQT 197
+ + + ++ G HS ++ SG Y+ G+N GQLG T
Sbjct: 559 DQEPLLSIDLGTAHSAAVTASGDCYTFGSNQHGQLGTNT 597
>AK023024-1|BAB14362.1| 396|Homo sapiens protein ( Homo sapiens
cDNA FLJ12962 fis, clone NT2RP2005694, weakly similar to
X-LINKED RETINITIS PIGMENTOSA GTPASE REGULATOR. ).
Length = 396
Score = 58.8 bits (136), Expect = 2e-08
Identities = 41/126 (32%), Positives = 62/126 (49%), Gaps = 6/126 (4%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 442
A G++H + + E G+ +S+G+ + + G P L + VI VA G++HS
Sbjct: 47 ALGVKHGVLLTEDGEVYSFGT-LLWRSGPV--EICPSSPILENALVGQYVITVATGSFHS 103
Query: 443 VALTNSGDLYSWGANSYGQCGL--ELYQTRKCHL----QHISSLIGVPIALITCGNNHTF 604
A+T++G Y WG NS GQC + + Y + S L+ V I + CG HT
Sbjct: 104 GAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQLACGEEHTL 163
Query: 605 VLSKSR 622
LS SR
Sbjct: 164 ALSISR 169
Score = 52.4 bits (120), Expect = 1e-06
Identities = 28/64 (43%), Positives = 42/64 (65%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG +H+LA+ + ++WG+ QLG A KP+ V+ LA + V+QVACGA+H
Sbjct: 155 LACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLAGRVVLQVACGAFH 212
Query: 440 SVAL 451
S+AL
Sbjct: 213 SLAL 216
Score = 51.2 bits (117), Expect = 3e-06
Identities = 35/124 (28%), Positives = 56/124 (45%), Gaps = 6/124 (4%)
Frame = +2
Query: 257 TIACGLQHSLAIDEWGQPFSWGSDSMGQLG-NNLGAHAQDKPKFVKG-----LATKNVIQ 418
T+A G HS A+ + G + WG +S GQ N + P + L ++Q
Sbjct: 95 TVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQ 154
Query: 419 VACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNH 598
+ACG H++AL+ S ++++WG Q GL Q + L G + + CG H
Sbjct: 155 LACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLAGRVVLQVACGAFH 212
Query: 599 TFVL 610
+ L
Sbjct: 213 SLAL 216
Score = 36.7 bits (81), Expect = 0.078
Identities = 22/88 (25%), Positives = 44/88 (50%)
Frame = +2
Query: 377 PKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSL 556
P+ + G K V+Q A G H V LT G++YS+G + +E+ + L+ ++L
Sbjct: 32 PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFGTLLWRSGPVEICPSSPI-LE--NAL 88
Query: 557 IGVPIALITCGNNHTFVLSKSRCGFWMG 640
+G + + G+ H+ ++ + + G
Sbjct: 89 VGQYVITVATGSFHSGAVTDNGVAYMWG 116
Score = 29.9 bits (64), Expect = 8.9
Identities = 14/41 (34%), Positives = 20/41 (48%)
Frame = +3
Query: 60 PTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQ 182
P L ++ VA G FHS ++++G Y G N GQ
Sbjct: 82 PILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQ 122
>AB053306-1|BAB69015.1| 396|Homo sapiens ALS2 protein.
Length = 396
Score = 58.8 bits (136), Expect = 2e-08
Identities = 40/126 (31%), Positives = 60/126 (47%), Gaps = 6/126 (4%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 442
A G++H + + E G+ +S+G+ + P L + VI VA G++HS
Sbjct: 47 ALGVKHGVLLTEDGEVYSFGTLPWRSGPVEI---CPSSPILENALVGQYVITVATGSFHS 103
Query: 443 VALTNSGDLYSWGANSYGQCGL--ELYQTRKCHL----QHISSLIGVPIALITCGNNHTF 604
A+T++G Y WG NS GQC + + Y + S L+ V I + CG HT
Sbjct: 104 GAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQLACGEEHTL 163
Query: 605 VLSKSR 622
LS SR
Sbjct: 164 ALSISR 169
Score = 52.4 bits (120), Expect = 1e-06
Identities = 28/64 (43%), Positives = 42/64 (65%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG +H+LA+ + ++WG+ QLG A KP+ V+ LA + V+QVACGA+H
Sbjct: 155 LACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLAGRVVLQVACGAFH 212
Query: 440 SVAL 451
S+AL
Sbjct: 213 SLAL 216
Score = 51.2 bits (117), Expect = 3e-06
Identities = 35/124 (28%), Positives = 56/124 (45%), Gaps = 6/124 (4%)
Frame = +2
Query: 257 TIACGLQHSLAIDEWGQPFSWGSDSMGQLG-NNLGAHAQDKPKFVKG-----LATKNVIQ 418
T+A G HS A+ + G + WG +S GQ N + P + L ++Q
Sbjct: 95 TVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQ 154
Query: 419 VACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNH 598
+ACG H++AL+ S ++++WG Q GL Q + L G + + CG H
Sbjct: 155 LACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLAGRVVLQVACGAFH 212
Query: 599 TFVL 610
+ L
Sbjct: 213 SLAL 216
Score = 37.1 bits (82), Expect = 0.059
Identities = 22/88 (25%), Positives = 44/88 (50%)
Frame = +2
Query: 377 PKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSL 556
P+ + G K V+Q A G H V LT G++YS+G + +E+ + L+ ++L
Sbjct: 32 PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFGTLPWRSGPVEICPSSPI-LE--NAL 88
Query: 557 IGVPIALITCGNNHTFVLSKSRCGFWMG 640
+G + + G+ H+ ++ + + G
Sbjct: 89 VGQYVITVATGSFHSGAVTDNGVAYMWG 116
Score = 29.9 bits (64), Expect = 8.9
Identities = 14/41 (34%), Positives = 20/41 (48%)
Frame = +3
Query: 60 PTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQ 182
P L ++ VA G FHS ++++G Y G N GQ
Sbjct: 82 PILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQ 122
>BC065375-1|AAH65375.1| 458|Homo sapiens secretion regulating
guanine nucleotide exchange factor protein.
Length = 458
Score = 57.6 bits (133), Expect = 4e-08
Identities = 43/129 (33%), Positives = 60/129 (46%), Gaps = 2/129 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFV--KGLATKNVIQVACGA 433
I G HS + + G F G + GQLG LG H +D P F K L + QVACG
Sbjct: 54 ITGGGGHSAVVTDGGDLFVCGLNKDGQLG--LG-HTEDIPYFTPCKSLFGCPIQQVACGW 110
Query: 434 YHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
++ LT +G + S G+NS+GQ G+ + R+C + L + I G H +
Sbjct: 111 DFTIMLTENGQVLSCGSNSFGQLGVP-HGPRRCVVPQAIELHKEKVVCIAAGLRHAVAAT 169
Query: 614 KSRCGFWMG 640
S F G
Sbjct: 170 ASGIVFQWG 178
Score = 54.0 bits (124), Expect = 5e-07
Identities = 36/106 (33%), Positives = 57/106 (53%), Gaps = 3/106 (2%)
Frame = +2
Query: 311 FSWGSDSMGQLGNNLGAHAQDK--PKFVKGLAT-KNVIQVACGAYHSVALTNSGDLYSWG 481
F+WG++S GQLG LG H +D P+ + ++V ++ G HS +T+ GDL+ G
Sbjct: 18 FAWGANSYGQLG--LG-HKEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDGGDLFVCG 74
Query: 482 ANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
N GQ GL + + SL G PI + CG + T +L+++
Sbjct: 75 LNKDGQLGLG-HTEDIPYFTPCKSLFGCPIQQVACGWDFTIMLTEN 119
Score = 53.6 bits (123), Expect = 6e-07
Identities = 33/90 (36%), Positives = 47/90 (52%), Gaps = 6/90 (6%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSD--SMGQL---GNNLGAHAQDK-PKFVKGLATKNVIQV 421
IA GL+H++A G F WG+ S G+ G L K P V GL + V
Sbjct: 158 IAAGLRHAVAATASGIVFQWGTGLASCGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCV 217
Query: 422 ACGAYHSVALTNSGDLYSWGANSYGQCGLE 511
G+ HS +LT++G++Y WG+N +GQ E
Sbjct: 218 LAGSDHSASLTDAGEVYVWGSNKHGQLANE 247
Score = 52.8 bits (121), Expect = 1e-06
Identities = 37/140 (26%), Positives = 58/140 (41%), Gaps = 15/140 (10%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ G HS ++ + G+ + WGS+ GQL N + + V + G H
Sbjct: 217 VLAGSDHSASLTDAGEVYVWGSNKHGQLANEAAFLPVPQKIEAHCFQNEKVTAIWSGWTH 276
Query: 440 SVALTNSGDLYSWGANSYGQCG--LELYQTRKCHLQHI--------SSLIGVPIAL---- 577
VA T +G +++WG YGQ G LE Y+ K Q +S+ P L
Sbjct: 277 LVAQTETGKMFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRPPNSMPSSPHCLTGAT 336
Query: 578 -ITCGNNHTFVLSKSRCGFW 634
++CG+ H + C W
Sbjct: 337 EVSCGSEHNLAIIGGVCYSW 356
Score = 50.8 bits (116), Expect = 4e-06
Identities = 38/134 (28%), Positives = 60/134 (44%), Gaps = 15/134 (11%)
Frame = +2
Query: 254 TTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNL----GAHAQDKPKFVKGLATKNVI-- 415
T I G H +A E G+ F+WG GQLG L G + + F+ N +
Sbjct: 268 TAIWSGWTHLVAQTETGKMFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRPPNSMPS 327
Query: 416 ---------QVACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVP 568
+V+CG+ H++A+ G YSWG N +G CG + + + + +L+
Sbjct: 328 SPHCLTGATEVSCGSEHNLAIIG-GVCYSWGWNEHGMCG-DGTEANVWAPKPVQALLSSS 385
Query: 569 IALITCGNNHTFVL 610
L+ CG H+ L
Sbjct: 386 GLLVGCGAGHSLAL 399
Score = 34.3 bits (75), Expect = 0.42
Identities = 15/32 (46%), Positives = 21/32 (65%)
Frame = +3
Query: 93 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG 188
IQ VA G ++ L+ +G + SCG+N GQLG
Sbjct: 103 IQQVACGWDFTIMLTENGQVLSCGSNSFGQLG 134
Score = 34.3 bits (75), Expect = 0.42
Identities = 15/57 (26%), Positives = 32/57 (56%)
Frame = +3
Query: 81 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCT 251
+++ + A+ +G H + + +G +++ G D GQLGR+ E+ G ++F C+
Sbjct: 263 QNEKVTAIWSGWTHLVAQTETGKMFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCS 319
Score = 33.1 bits (72), Expect = 0.96
Identities = 28/104 (26%), Positives = 50/104 (48%), Gaps = 2/104 (1%)
Frame = +3
Query: 45 DLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG-RQTESDNGKNP 221
D+++ L+ + + ++ + G HS +++ G L+ CG N GQLG TE P
Sbjct: 35 DVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDGGDLFVCGLNKDGQLGLGHTEDIPYFTP 94
Query: 222 ALVETFKDCTIRQ*HVAFNI-L*L*MNGDSLSVGALTVWGNLAI 350
++ C I+Q ++ + L NG LS G+ +G L +
Sbjct: 95 C--KSLFGCPIQQVACGWDFTIMLTENGQVLSCGS-NSFGQLGV 135
Score = 31.1 bits (67), Expect = 3.9
Identities = 13/23 (56%), Positives = 16/23 (69%)
Frame = +2
Query: 440 SVALTNSGDLYSWGANSYGQCGL 508
S A + L++WGANSYGQ GL
Sbjct: 8 SEAAPAAAALFAWGANSYGQLGL 30
Score = 30.7 bits (66), Expect = 5.1
Identities = 14/38 (36%), Positives = 21/38 (55%)
Frame = +3
Query: 81 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQ 194
E+ V AG HS L+++G +Y G+N GQL +
Sbjct: 210 ENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQLANE 247
>AJ243951-1|CAB60833.1| 288|Homo sapiens deafness locus associated
putative guanine nucleotide exchange factor protein.
Length = 288
Score = 57.6 bits (133), Expect = 4e-08
Identities = 43/129 (33%), Positives = 60/129 (46%), Gaps = 2/129 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFV--KGLATKNVIQVACGA 433
I G HS + + G F G + GQLG LG H +D P F K L + QVACG
Sbjct: 54 ITGGGGHSAVVTDGGDLFVCGLNKDGQLG--LG-HTEDIPYFTPCKSLFGCPIQQVACGW 110
Query: 434 YHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
++ LT +G + S G+NS+GQ G+ + R+C + L + I G H +
Sbjct: 111 DFTIMLTENGQVLSCGSNSFGQLGVP-HGPRRCVVPQAIELHKEKVVCIAAGLRHAVAAT 169
Query: 614 KSRCGFWMG 640
S F G
Sbjct: 170 ASGIVFQWG 178
Score = 54.0 bits (124), Expect = 5e-07
Identities = 36/106 (33%), Positives = 57/106 (53%), Gaps = 3/106 (2%)
Frame = +2
Query: 311 FSWGSDSMGQLGNNLGAHAQDK--PKFVKGLAT-KNVIQVACGAYHSVALTNSGDLYSWG 481
F+WG++S GQLG LG H +D P+ + ++V ++ G HS +T+ GDL+ G
Sbjct: 18 FAWGANSYGQLG--LG-HKEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDGGDLFVCG 74
Query: 482 ANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
N GQ GL + + SL G PI + CG + T +L+++
Sbjct: 75 LNKDGQLGLG-HTEDIPYFTPCKSLFGCPIQQVACGWDFTIMLTEN 119
Score = 53.6 bits (123), Expect = 6e-07
Identities = 33/90 (36%), Positives = 47/90 (52%), Gaps = 6/90 (6%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSD--SMGQL---GNNLGAHAQDK-PKFVKGLATKNVIQV 421
IA GL+H++A G F WG+ S G+ G L K P V GL + V
Sbjct: 158 IAAGLRHAVAATASGIVFQWGTGLASCGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCV 217
Query: 422 ACGAYHSVALTNSGDLYSWGANSYGQCGLE 511
G+ HS +LT++G++Y WG+N +GQ E
Sbjct: 218 LAGSDHSASLTDAGEVYVWGSNKHGQLANE 247
Score = 34.3 bits (75), Expect = 0.42
Identities = 15/32 (46%), Positives = 21/32 (65%)
Frame = +3
Query: 93 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG 188
IQ VA G ++ L+ +G + SCG+N GQLG
Sbjct: 103 IQQVACGWDFTIMLTENGQVLSCGSNSFGQLG 134
Score = 33.1 bits (72), Expect = 0.96
Identities = 28/104 (26%), Positives = 50/104 (48%), Gaps = 2/104 (1%)
Frame = +3
Query: 45 DLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG-RQTESDNGKNP 221
D+++ L+ + + ++ + G HS +++ G L+ CG N GQLG TE P
Sbjct: 35 DVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDGGDLFVCGLNKDGQLGLGHTEDIPYFTP 94
Query: 222 ALVETFKDCTIRQ*HVAFNI-L*L*MNGDSLSVGALTVWGNLAI 350
++ C I+Q ++ + L NG LS G+ +G L +
Sbjct: 95 C--KSLFGCPIQQVACGWDFTIMLTENGQVLSCGS-NSFGQLGV 135
Score = 31.1 bits (67), Expect = 3.9
Identities = 13/23 (56%), Positives = 16/23 (69%)
Frame = +2
Query: 440 SVALTNSGDLYSWGANSYGQCGL 508
S A + L++WGANSYGQ GL
Sbjct: 8 SEAAPAAAALFAWGANSYGQLGL 30
Score = 30.7 bits (66), Expect = 5.1
Identities = 14/38 (36%), Positives = 21/38 (55%)
Frame = +3
Query: 81 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQ 194
E+ V AG HS L+++G +Y G+N GQL +
Sbjct: 210 ENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQLANE 247
>AJ243950-1|CAB60832.1| 458|Homo sapiens deafness locus associated
putative guanine nucleotide exchange factor protein.
Length = 458
Score = 57.6 bits (133), Expect = 4e-08
Identities = 43/129 (33%), Positives = 60/129 (46%), Gaps = 2/129 (1%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFV--KGLATKNVIQVACGA 433
I G HS + + G F G + GQLG LG H +D P F K L + QVACG
Sbjct: 54 ITGGGGHSAVVTDGGDLFVCGLNKDGQLG--LG-HTEDIPYFTPCKSLFGCPIQQVACGW 110
Query: 434 YHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
++ LT +G + S G+NS+GQ G+ + R+C + L + I G H +
Sbjct: 111 DFTIMLTENGQVLSCGSNSFGQLGVP-HGPRRCVVPQAIELHKEKVVCIAAGLRHAVAAT 169
Query: 614 KSRCGFWMG 640
S F G
Sbjct: 170 ASGIVFQWG 178
Score = 54.0 bits (124), Expect = 5e-07
Identities = 36/106 (33%), Positives = 57/106 (53%), Gaps = 3/106 (2%)
Frame = +2
Query: 311 FSWGSDSMGQLGNNLGAHAQDK--PKFVKGLAT-KNVIQVACGAYHSVALTNSGDLYSWG 481
F+WG++S GQLG LG H +D P+ + ++V ++ G HS +T+ GDL+ G
Sbjct: 18 FAWGANSYGQLG--LG-HKEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDGGDLFVCG 74
Query: 482 ANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSKS 619
N GQ GL + + SL G PI + CG + T +L+++
Sbjct: 75 LNKDGQLGLG-HTEDIPYFTPCKSLFGCPIQQVACGWDFTIMLTEN 119
Score = 53.6 bits (123), Expect = 6e-07
Identities = 33/90 (36%), Positives = 47/90 (52%), Gaps = 6/90 (6%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSD--SMGQL---GNNLGAHAQDK-PKFVKGLATKNVIQV 421
IA GL+H++A G F WG+ S G+ G L K P V GL + V
Sbjct: 158 IAAGLRHAVAATASGIVFQWGTGLASCGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCV 217
Query: 422 ACGAYHSVALTNSGDLYSWGANSYGQCGLE 511
G+ HS +LT++G++Y WG+N +GQ E
Sbjct: 218 LAGSDHSASLTDAGEVYVWGSNKHGQLANE 247
Score = 52.8 bits (121), Expect = 1e-06
Identities = 37/140 (26%), Positives = 58/140 (41%), Gaps = 15/140 (10%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ G HS ++ + G+ + WGS+ GQL N + + V + G H
Sbjct: 217 VLAGSDHSASLTDAGEVYVWGSNKHGQLANEAAFLPVPQKIEAHCFQNEKVTAIWSGWTH 276
Query: 440 SVALTNSGDLYSWGANSYGQCG--LELYQTRKCHLQHI--------SSLIGVPIAL---- 577
VA T +G +++WG YGQ G LE Y+ K Q +S+ P L
Sbjct: 277 LVAQTETGKMFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRPPNSMPSSPHCLTGAT 336
Query: 578 -ITCGNNHTFVLSKSRCGFW 634
++CG+ H + C W
Sbjct: 337 EVSCGSEHNLAIIGGVCYSW 356
Score = 50.8 bits (116), Expect = 4e-06
Identities = 38/134 (28%), Positives = 60/134 (44%), Gaps = 15/134 (11%)
Frame = +2
Query: 254 TTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNL----GAHAQDKPKFVKGLATKNVI-- 415
T I G H +A E G+ F+WG GQLG L G + + F+ N +
Sbjct: 268 TAIWSGWTHLVAQTETGKMFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRPPNSMPS 327
Query: 416 ---------QVACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVP 568
+V+CG+ H++A+ G YSWG N +G CG + + + + +L+
Sbjct: 328 SPHCLTGATEVSCGSEHNLAIIG-GVCYSWGWNEHGMCG-DGTEANVWAPKPVQALLSSS 385
Query: 569 IALITCGNNHTFVL 610
L+ CG H+ L
Sbjct: 386 GLLVGCGAGHSLAL 399
Score = 34.3 bits (75), Expect = 0.42
Identities = 15/32 (46%), Positives = 21/32 (65%)
Frame = +3
Query: 93 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG 188
IQ VA G ++ L+ +G + SCG+N GQLG
Sbjct: 103 IQQVACGWDFTIMLTENGQVLSCGSNSFGQLG 134
Score = 34.3 bits (75), Expect = 0.42
Identities = 15/57 (26%), Positives = 32/57 (56%)
Frame = +3
Query: 81 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCT 251
+++ + A+ +G H + + +G +++ G D GQLGR+ E+ G ++F C+
Sbjct: 263 QNEKVTAIWSGWTHLVAQTETGKMFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCS 319
Score = 33.1 bits (72), Expect = 0.96
Identities = 28/104 (26%), Positives = 50/104 (48%), Gaps = 2/104 (1%)
Frame = +3
Query: 45 DLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG-RQTESDNGKNP 221
D+++ L+ + + ++ + G HS +++ G L+ CG N GQLG TE P
Sbjct: 35 DVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDGGDLFVCGLNKDGQLGLGHTEDIPYFTP 94
Query: 222 ALVETFKDCTIRQ*HVAFNI-L*L*MNGDSLSVGALTVWGNLAI 350
++ C I+Q ++ + L NG LS G+ +G L +
Sbjct: 95 C--KSLFGCPIQQVACGWDFTIMLTENGQVLSCGS-NSFGQLGV 135
Score = 31.1 bits (67), Expect = 3.9
Identities = 13/23 (56%), Positives = 16/23 (69%)
Frame = +2
Query: 440 SVALTNSGDLYSWGANSYGQCGL 508
S A + L++WGANSYGQ GL
Sbjct: 8 SEAAPAAAALFAWGANSYGQLGL 30
Score = 30.7 bits (66), Expect = 5.1
Identities = 14/38 (36%), Positives = 21/38 (55%)
Frame = +3
Query: 81 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQ 194
E+ V AG HS L+++G +Y G+N GQL +
Sbjct: 210 ENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQLANE 247
>X12654-1|CAA31182.1| 421|Homo sapiens protein ( Human mRNA for
cell cycle gene RCC1. ).
Length = 421
Score = 55.2 bits (127), Expect = 2e-07
Identities = 30/115 (26%), Positives = 56/115 (48%)
Frame = +2
Query: 269 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 448
G H++ + + GQ +S+G + G LG + + L K V+QV+ G H+ A
Sbjct: 75 GGMHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK-VVQVSAGDSHTAA 133
Query: 449 LTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
LT+ G ++ WG+ + L + K + + + VP+ + GN+H +L+
Sbjct: 134 LTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVASGNDHLVMLT 188
Score = 51.6 bits (118), Expect = 3e-06
Identities = 32/119 (26%), Positives = 55/119 (46%), Gaps = 1/119 (0%)
Frame = +2
Query: 269 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 448
G H++ +D G+ +S G G+LG GA + P + L V VACGA A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYA 359
Query: 449 LTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIAL-ITCGNNHTFVLSKSR 622
+T G +++WG + Q G + ++ + + + L ++ G HT +L K +
Sbjct: 360 VTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKDK 418
Score = 44.8 bits (101), Expect = 3e-04
Identities = 25/78 (32%), Positives = 38/78 (48%)
Frame = +2
Query: 272 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVAL 451
+ H E G + G +GQLG LG + ++ K ++V+Q G H+V L
Sbjct: 25 VSHRSHSTEPGLVLTLGQGDVGQLG--LGENVMERKKPALVSIPEDVVQAEAGGMHTVCL 82
Query: 452 TNSGDLYSWGANSYGQCG 505
+ SG +YS+G N G G
Sbjct: 83 SKSGQVYSFGCNDEGALG 100
Score = 42.7 bits (96), Expect = 0.001
Identities = 32/93 (34%), Positives = 45/93 (48%), Gaps = 4/93 (4%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGS--DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGA 433
++ G H+ A+ + G+ F WGS D+ G +G P V+ V++VA G
Sbjct: 124 VSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQ--LDVPVVKVASGN 181
Query: 434 YHSVALTNSGDLYSWGANSYGQCGL--ELYQTR 526
H V LT GDLY+ G GQ G EL+ R
Sbjct: 182 DHLVMLTADGDLYTLGCGEQGQLGRVPELFANR 214
Score = 41.1 bits (92), Expect = 0.004
Identities = 27/60 (45%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Frame = +3
Query: 57 KPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKN-PALVE 233
KP L E D +QA A G H++ LS SG +YS G ND G LGR T + + P VE
Sbjct: 59 KPALVSIPE-DVVQAEAGG-MHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE 116
Score = 41.1 bits (92), Expect = 0.004
Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 2/119 (1%)
Frame = +2
Query: 266 CGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGL--ATKNVIQVACGAYH 439
CG + AI G + +G + QLG G + P+ + +TK+ + + G +H
Sbjct: 247 CGAYFTFAISHEGHVYGFGLSNYHQLGTP-GTESCFIPQNLTSFKNSTKSWVGFSGGQHH 305
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSK 616
+V + + G YS G YG+ GL K IS L V + + CG + + ++K
Sbjct: 306 TVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPAV--SSVACGASVGYAVTK 362
Score = 36.7 bits (81), Expect = 0.078
Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 1/67 (1%)
Frame = +2
Query: 254 TTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFV-KGLATKNVIQVACG 430
+++ACG A+ + G+ F+WG + QLG A + + K L + V+ V+ G
Sbjct: 348 SSVACGASVGYAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSG 407
Query: 431 AYHSVAL 451
H+V L
Sbjct: 408 GQHTVLL 414
Score = 31.5 bits (68), Expect = 2.9
Identities = 15/33 (45%), Positives = 20/33 (60%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE 200
VA+G H + L+ G LY+ G + GQLGR E
Sbjct: 177 VASGNDHLVMLTADGDLYTLGCGEQGQLGRVPE 209
>X06130-1|CAA29496.1| 421|Homo sapiens protein ( Human mRNA for
cell cycle gene RCC1. ).
Length = 421
Score = 55.2 bits (127), Expect = 2e-07
Identities = 30/115 (26%), Positives = 56/115 (48%)
Frame = +2
Query: 269 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 448
G H++ + + GQ +S+G + G LG + + L K V+QV+ G H+ A
Sbjct: 75 GGMHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK-VVQVSAGDSHTAA 133
Query: 449 LTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
LT+ G ++ WG+ + L + K + + + VP+ + GN+H +L+
Sbjct: 134 LTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVASGNDHLVMLT 188
Score = 51.6 bits (118), Expect = 3e-06
Identities = 32/119 (26%), Positives = 55/119 (46%), Gaps = 1/119 (0%)
Frame = +2
Query: 269 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 448
G H++ +D G+ +S G G+LG GA + P + L V VACGA A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYA 359
Query: 449 LTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIAL-ITCGNNHTFVLSKSR 622
+T G +++WG + Q G + ++ + + + L ++ G HT +L K +
Sbjct: 360 VTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKDK 418
Score = 44.8 bits (101), Expect = 3e-04
Identities = 25/78 (32%), Positives = 38/78 (48%)
Frame = +2
Query: 272 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVAL 451
+ H E G + G +GQLG LG + ++ K ++V+Q G H+V L
Sbjct: 25 VSHRSHSTEPGLVLTLGQGDVGQLG--LGENVMERKKPALVSIPEDVVQAEAGGMHTVCL 82
Query: 452 TNSGDLYSWGANSYGQCG 505
+ SG +YS+G N G G
Sbjct: 83 SKSGQVYSFGCNDEGALG 100
Score = 42.7 bits (96), Expect = 0.001
Identities = 32/93 (34%), Positives = 45/93 (48%), Gaps = 4/93 (4%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGS--DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGA 433
++ G H+ A+ + G+ F WGS D+ G +G P V+ V++VA G
Sbjct: 124 VSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQ--LDVPVVKVASGN 181
Query: 434 YHSVALTNSGDLYSWGANSYGQCGL--ELYQTR 526
H V LT GDLY+ G GQ G EL+ R
Sbjct: 182 DHLVMLTADGDLYTLGCGEQGQLGRVPELFANR 214
Score = 41.1 bits (92), Expect = 0.004
Identities = 27/60 (45%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Frame = +3
Query: 57 KPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKN-PALVE 233
KP L E D +QA A G H++ LS SG +YS G ND G LGR T + + P VE
Sbjct: 59 KPALVSIPE-DVVQAEAGG-MHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE 116
Score = 41.1 bits (92), Expect = 0.004
Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 2/119 (1%)
Frame = +2
Query: 266 CGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGL--ATKNVIQVACGAYH 439
CG + AI G + +G + QLG G + P+ + +TK+ + + G +H
Sbjct: 247 CGAYFTFAISHEGHVYGFGLSNYHQLGTP-GTESCFIPQNLTSFKNSTKSWVGFSGGQHH 305
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSK 616
+V + + G YS G YG+ GL K IS L V + + CG + + ++K
Sbjct: 306 TVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPAV--SSVACGASVGYAVTK 362
Score = 36.7 bits (81), Expect = 0.078
Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 1/67 (1%)
Frame = +2
Query: 254 TTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFV-KGLATKNVIQVACG 430
+++ACG A+ + G+ F+WG + QLG A + + K L + V+ V+ G
Sbjct: 348 SSVACGASVGYAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSG 407
Query: 431 AYHSVAL 451
H+V L
Sbjct: 408 GQHTVLL 414
Score = 31.5 bits (68), Expect = 2.9
Identities = 15/33 (45%), Positives = 20/33 (60%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE 200
VA+G H + L+ G LY+ G + GQLGR E
Sbjct: 177 VASGNDHLVMLTADGDLYTLGCGEQGQLGRVPE 209
>D00591-1|BAA00469.1| 421|Homo sapiens RCC1 protein.
Length = 421
Score = 55.2 bits (127), Expect = 2e-07
Identities = 30/115 (26%), Positives = 56/115 (48%)
Frame = +2
Query: 269 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 448
G H++ + + GQ +S+G + G LG + + L K V+QV+ G H+ A
Sbjct: 75 GGMHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK-VVQVSAGDSHTAA 133
Query: 449 LTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
LT+ G ++ WG+ + L + K + + + VP+ + GN+H +L+
Sbjct: 134 LTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVASGNDHLVMLT 188
Score = 51.6 bits (118), Expect = 3e-06
Identities = 32/119 (26%), Positives = 55/119 (46%), Gaps = 1/119 (0%)
Frame = +2
Query: 269 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 448
G H++ +D G+ +S G G+LG GA + P + L V VACGA A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYA 359
Query: 449 LTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIAL-ITCGNNHTFVLSKSR 622
+T G +++WG + Q G + ++ + + + L ++ G HT +L K +
Sbjct: 360 VTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKDK 418
Score = 44.8 bits (101), Expect = 3e-04
Identities = 25/78 (32%), Positives = 38/78 (48%)
Frame = +2
Query: 272 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVAL 451
+ H E G + G +GQLG LG + ++ K ++V+Q G H+V L
Sbjct: 25 VSHRSHSTEPGLVLTLGQGDVGQLG--LGENVMERKKPALVSIPEDVVQAEAGGMHTVCL 82
Query: 452 TNSGDLYSWGANSYGQCG 505
+ SG +YS+G N G G
Sbjct: 83 SKSGQVYSFGCNDEGALG 100
Score = 42.7 bits (96), Expect = 0.001
Identities = 32/93 (34%), Positives = 45/93 (48%), Gaps = 4/93 (4%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGS--DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGA 433
++ G H+ A+ + G+ F WGS D+ G +G P V+ V++VA G
Sbjct: 124 VSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQ--LDVPVVKVASGN 181
Query: 434 YHSVALTNSGDLYSWGANSYGQCGL--ELYQTR 526
H V LT GDLY+ G GQ G EL+ R
Sbjct: 182 DHLVMLTADGDLYTLGCGEQGQLGRVPELFANR 214
Score = 41.1 bits (92), Expect = 0.004
Identities = 27/60 (45%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Frame = +3
Query: 57 KPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKN-PALVE 233
KP L E D +QA A G H++ LS SG +YS G ND G LGR T + + P VE
Sbjct: 59 KPALVSIPE-DVVQAEAGG-MHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE 116
Score = 41.1 bits (92), Expect = 0.004
Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 2/119 (1%)
Frame = +2
Query: 266 CGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGL--ATKNVIQVACGAYH 439
CG + AI G + +G + QLG G + P+ + +TK+ + + G +H
Sbjct: 247 CGAYFTFAISHEGHVYGFGLSNYHQLGTP-GTESCFIPQNLTSFKNSTKSWVGFSGGQHH 305
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSK 616
+V + + G YS G YG+ GL K IS L V + + CG + + ++K
Sbjct: 306 TVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPAV--SSVACGASVGYAVTK 362
Score = 36.7 bits (81), Expect = 0.078
Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 1/67 (1%)
Frame = +2
Query: 254 TTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFV-KGLATKNVIQVACG 430
+++ACG A+ + G+ F+WG + QLG A + + K L + V+ V+ G
Sbjct: 348 SSVACGASVGYAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSG 407
Query: 431 AYHSVAL 451
H+V L
Sbjct: 408 GQHTVLL 414
Score = 31.5 bits (68), Expect = 2.9
Identities = 15/33 (45%), Positives = 20/33 (60%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE 200
VA+G H + L+ G LY+ G + GQLGR E
Sbjct: 177 VASGNDHLVMLTADGDLYTLGCGEQGQLGRVPE 209
>CR407693-1|CAG28621.1| 421|Homo sapiens CHC1 protein.
Length = 421
Score = 55.2 bits (127), Expect = 2e-07
Identities = 30/115 (26%), Positives = 56/115 (48%)
Frame = +2
Query: 269 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 448
G H++ + + GQ +S+G + G LG + + L K V+QV+ G H+ A
Sbjct: 75 GGMHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK-VVQVSAGDSHTAA 133
Query: 449 LTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
LT+ G ++ WG+ + L + K + + + VP+ + GN+H +L+
Sbjct: 134 LTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVASGNDHLVMLT 188
Score = 51.6 bits (118), Expect = 3e-06
Identities = 32/119 (26%), Positives = 55/119 (46%), Gaps = 1/119 (0%)
Frame = +2
Query: 269 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 448
G H++ +D G+ +S G G+LG GA + P + L V VACGA A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYA 359
Query: 449 LTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIAL-ITCGNNHTFVLSKSR 622
+T G +++WG + Q G + ++ + + + L ++ G HT +L K +
Sbjct: 360 VTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKDK 418
Score = 44.8 bits (101), Expect = 3e-04
Identities = 25/78 (32%), Positives = 38/78 (48%)
Frame = +2
Query: 272 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVAL 451
+ H E G + G +GQLG LG + ++ K ++V+Q G H+V L
Sbjct: 25 VSHRSHSTEPGLVLTLGQGDVGQLG--LGENVMERKKPALVSIPEDVVQAEAGGMHTVCL 82
Query: 452 TNSGDLYSWGANSYGQCG 505
+ SG +YS+G N G G
Sbjct: 83 SKSGQVYSFGCNDEGALG 100
Score = 42.7 bits (96), Expect = 0.001
Identities = 32/93 (34%), Positives = 45/93 (48%), Gaps = 4/93 (4%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGS--DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGA 433
++ G H+ A+ + G+ F WGS D+ G +G P V+ V++VA G
Sbjct: 124 VSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQ--LDVPVVKVASGN 181
Query: 434 YHSVALTNSGDLYSWGANSYGQCGL--ELYQTR 526
H V LT GDLY+ G GQ G EL+ R
Sbjct: 182 DHLVMLTADGDLYTLGCGEQGQLGRVPELFANR 214
Score = 41.1 bits (92), Expect = 0.004
Identities = 27/60 (45%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Frame = +3
Query: 57 KPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKN-PALVE 233
KP L E D +QA A G H++ LS SG +YS G ND G LGR T + + P VE
Sbjct: 59 KPALVSIPE-DVVQAEAGG-MHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE 116
Score = 41.1 bits (92), Expect = 0.004
Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 2/119 (1%)
Frame = +2
Query: 266 CGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGL--ATKNVIQVACGAYH 439
CG + AI G + +G + QLG G + P+ + +TK+ + + G +H
Sbjct: 247 CGAYFTFAISHEGHVYGFGLSNYHQLGTP-GTESCFIPQNLTSFKNSTKSWVGFSGGQHH 305
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSK 616
+V + + G YS G YG+ GL K IS L V + + CG + + ++K
Sbjct: 306 TVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPAV--SSVACGASVGYAVTK 362
Score = 36.7 bits (81), Expect = 0.078
Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 1/67 (1%)
Frame = +2
Query: 254 TTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFV-KGLATKNVIQVACG 430
+++ACG A+ + G+ F+WG + QLG A + + K L + V+ V+ G
Sbjct: 348 SSVACGASVGYAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSG 407
Query: 431 AYHSVAL 451
H+V L
Sbjct: 408 GQHTVLL 414
Score = 31.5 bits (68), Expect = 2.9
Identities = 15/33 (45%), Positives = 20/33 (60%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE 200
VA+G H + L+ G LY+ G + GQLGR E
Sbjct: 177 VASGNDHLVMLTADGDLYTLGCGEQGQLGRVPE 209
>BC069198-1|AAH69198.1| 452|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 452
Score = 55.2 bits (127), Expect = 2e-07
Identities = 30/115 (26%), Positives = 56/115 (48%)
Frame = +2
Query: 269 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 448
G H++ + + GQ +S+G + G LG + + L K V+QV+ G H+ A
Sbjct: 106 GGMHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK-VVQVSAGDSHTAA 164
Query: 449 LTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
LT+ G ++ WG+ + L + K + + + VP+ + GN+H +L+
Sbjct: 165 LTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVASGNDHLVMLT 219
Score = 51.6 bits (118), Expect = 3e-06
Identities = 32/119 (26%), Positives = 55/119 (46%), Gaps = 1/119 (0%)
Frame = +2
Query: 269 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 448
G H++ +D G+ +S G G+LG GA + P + L V VACGA A
Sbjct: 333 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYA 390
Query: 449 LTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIAL-ITCGNNHTFVLSKSR 622
+T G +++WG + Q G + ++ + + + L ++ G HT +L K +
Sbjct: 391 VTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKDK 449
Score = 44.8 bits (101), Expect = 3e-04
Identities = 25/78 (32%), Positives = 38/78 (48%)
Frame = +2
Query: 272 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVAL 451
+ H E G + G +GQLG LG + ++ K ++V+Q G H+V L
Sbjct: 56 VSHRSHSTEPGLVLTLGQGDVGQLG--LGENVMERKKPALVSIPEDVVQAEAGGMHTVCL 113
Query: 452 TNSGDLYSWGANSYGQCG 505
+ SG +YS+G N G G
Sbjct: 114 SKSGQVYSFGCNDEGALG 131
Score = 42.7 bits (96), Expect = 0.001
Identities = 32/93 (34%), Positives = 45/93 (48%), Gaps = 4/93 (4%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGS--DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGA 433
++ G H+ A+ + G+ F WGS D+ G +G P V+ V++VA G
Sbjct: 155 VSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQ--LDVPVVKVASGN 212
Query: 434 YHSVALTNSGDLYSWGANSYGQCGL--ELYQTR 526
H V LT GDLY+ G GQ G EL+ R
Sbjct: 213 DHLVMLTADGDLYTLGCGEQGQLGRVPELFANR 245
Score = 41.1 bits (92), Expect = 0.004
Identities = 27/60 (45%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Frame = +3
Query: 57 KPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKN-PALVE 233
KP L E D +QA A G H++ LS SG +YS G ND G LGR T + + P VE
Sbjct: 90 KPALVSIPE-DVVQAEAGG-MHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE 147
Score = 41.1 bits (92), Expect = 0.004
Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 2/119 (1%)
Frame = +2
Query: 266 CGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGL--ATKNVIQVACGAYH 439
CG + AI G + +G + QLG G + P+ + +TK+ + + G +H
Sbjct: 278 CGAYFTFAISHEGHVYGFGLSNYHQLGTP-GTESCFIPQNLTSFKNSTKSWVGFSGGQHH 336
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSK 616
+V + + G YS G YG+ GL K IS L V + + CG + + ++K
Sbjct: 337 TVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPAV--SSVACGASVGYAVTK 393
Score = 36.7 bits (81), Expect = 0.078
Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 1/67 (1%)
Frame = +2
Query: 254 TTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFV-KGLATKNVIQVACG 430
+++ACG A+ + G+ F+WG + QLG A + + K L + V+ V+ G
Sbjct: 379 SSVACGASVGYAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSG 438
Query: 431 AYHSVAL 451
H+V L
Sbjct: 439 GQHTVLL 445
Score = 31.5 bits (68), Expect = 2.9
Identities = 15/33 (45%), Positives = 20/33 (60%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE 200
VA+G H + L+ G LY+ G + GQLGR E
Sbjct: 208 VASGNDHLVMLTADGDLYTLGCGEQGQLGRVPE 240
>BC036903-1|AAH36903.1| 421|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 421
Score = 55.2 bits (127), Expect = 2e-07
Identities = 30/115 (26%), Positives = 56/115 (48%)
Frame = +2
Query: 269 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 448
G H++ + + GQ +S+G + G LG + + L K V+QV+ G H+ A
Sbjct: 75 GGMHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK-VVQVSAGDSHTAA 133
Query: 449 LTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
LT+ G ++ WG+ + L + K + + + VP+ + GN+H +L+
Sbjct: 134 LTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVASGNDHLVMLT 188
Score = 51.6 bits (118), Expect = 3e-06
Identities = 32/119 (26%), Positives = 55/119 (46%), Gaps = 1/119 (0%)
Frame = +2
Query: 269 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 448
G H++ +D G+ +S G G+LG GA + P + L V VACGA A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYA 359
Query: 449 LTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIAL-ITCGNNHTFVLSKSR 622
+T G +++WG + Q G + ++ + + + L ++ G HT +L K +
Sbjct: 360 VTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKDK 418
Score = 44.8 bits (101), Expect = 3e-04
Identities = 25/78 (32%), Positives = 38/78 (48%)
Frame = +2
Query: 272 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVAL 451
+ H E G + G +GQLG LG + ++ K ++V+Q G H+V L
Sbjct: 25 VSHRSHSTEPGLVLTLGQGDVGQLG--LGENVMERKKPALVSIPEDVVQAEAGGMHTVCL 82
Query: 452 TNSGDLYSWGANSYGQCG 505
+ SG +YS+G N G G
Sbjct: 83 SKSGQVYSFGCNDEGALG 100
Score = 42.7 bits (96), Expect = 0.001
Identities = 32/93 (34%), Positives = 45/93 (48%), Gaps = 4/93 (4%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGS--DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGA 433
++ G H+ A+ + G+ F WGS D+ G +G P V+ V++VA G
Sbjct: 124 VSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQ--LDVPVVKVASGN 181
Query: 434 YHSVALTNSGDLYSWGANSYGQCGL--ELYQTR 526
H V LT GDLY+ G GQ G EL+ R
Sbjct: 182 DHLVMLTADGDLYTLGCGEQGQLGRVPELFANR 214
Score = 41.1 bits (92), Expect = 0.004
Identities = 27/60 (45%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Frame = +3
Query: 57 KPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKN-PALVE 233
KP L E D +QA A G H++ LS SG +YS G ND G LGR T + + P VE
Sbjct: 59 KPALVSIPE-DVVQAEAGG-MHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE 116
Score = 41.1 bits (92), Expect = 0.004
Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 2/119 (1%)
Frame = +2
Query: 266 CGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGL--ATKNVIQVACGAYH 439
CG + AI G + +G + QLG G + P+ + +TK+ + + G +H
Sbjct: 247 CGAYFTFAISHEGHVYGFGLSNYHQLGTP-GTESCFIPQNLTSFKNSTKSWVGFSGGQHH 305
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSK 616
+V + + G YS G YG+ GL K IS L V + + CG + + ++K
Sbjct: 306 TVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPAV--SSVACGASVGYAVTK 362
Score = 36.7 bits (81), Expect = 0.078
Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 1/67 (1%)
Frame = +2
Query: 254 TTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFV-KGLATKNVIQVACG 430
+++ACG A+ + G+ F+WG + QLG A + + K L + V+ V+ G
Sbjct: 348 SSVACGASVGYAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSG 407
Query: 431 AYHSVAL 451
H+V L
Sbjct: 408 GQHTVLL 414
Score = 31.5 bits (68), Expect = 2.9
Identities = 15/33 (45%), Positives = 20/33 (60%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE 200
VA+G H + L+ G LY+ G + GQLGR E
Sbjct: 177 VASGNDHLVMLTADGDLYTLGCGEQGQLGRVPE 209
>BC010067-1|AAH10067.1| 421|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 421
Score = 55.2 bits (127), Expect = 2e-07
Identities = 30/115 (26%), Positives = 56/115 (48%)
Frame = +2
Query: 269 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 448
G H++ + + GQ +S+G + G LG + + L K V+QV+ G H+ A
Sbjct: 75 GGMHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK-VVQVSAGDSHTAA 133
Query: 449 LTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
LT+ G ++ WG+ + L + K + + + VP+ + GN+H +L+
Sbjct: 134 LTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVASGNDHLVMLT 188
Score = 51.6 bits (118), Expect = 3e-06
Identities = 32/119 (26%), Positives = 55/119 (46%), Gaps = 1/119 (0%)
Frame = +2
Query: 269 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 448
G H++ +D G+ +S G G+LG GA + P + L V VACGA A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYA 359
Query: 449 LTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIAL-ITCGNNHTFVLSKSR 622
+T G +++WG + Q G + ++ + + + L ++ G HT +L K +
Sbjct: 360 VTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKDK 418
Score = 44.8 bits (101), Expect = 3e-04
Identities = 25/78 (32%), Positives = 38/78 (48%)
Frame = +2
Query: 272 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVAL 451
+ H E G + G +GQLG LG + ++ K ++V+Q G H+V L
Sbjct: 25 VSHRSHSTEPGLVLTLGQGDVGQLG--LGENVMERKKPALVSIPEDVVQAEAGGMHTVCL 82
Query: 452 TNSGDLYSWGANSYGQCG 505
+ SG +YS+G N G G
Sbjct: 83 SKSGQVYSFGCNDEGALG 100
Score = 42.7 bits (96), Expect = 0.001
Identities = 32/93 (34%), Positives = 45/93 (48%), Gaps = 4/93 (4%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGS--DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGA 433
++ G H+ A+ + G+ F WGS D+ G +G P V+ V++VA G
Sbjct: 124 VSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQ--LDVPVVKVASGN 181
Query: 434 YHSVALTNSGDLYSWGANSYGQCGL--ELYQTR 526
H V LT GDLY+ G GQ G EL+ R
Sbjct: 182 DHLVMLTADGDLYTLGCGEQGQLGRVPELFANR 214
Score = 41.1 bits (92), Expect = 0.004
Identities = 27/60 (45%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Frame = +3
Query: 57 KPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKN-PALVE 233
KP L E D +QA A G H++ LS SG +YS G ND G LGR T + + P VE
Sbjct: 59 KPALVSIPE-DVVQAEAGG-MHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE 116
Score = 41.1 bits (92), Expect = 0.004
Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 2/119 (1%)
Frame = +2
Query: 266 CGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGL--ATKNVIQVACGAYH 439
CG + AI G + +G + QLG G + P+ + +TK+ + + G +H
Sbjct: 247 CGAYFTFAISHEGHVYGFGLSNYHQLGTP-GTESCFIPQNLTSFKNSTKSWVGFSGGQHH 305
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSK 616
+V + + G YS G YG+ GL K IS L V + + CG + + ++K
Sbjct: 306 TVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPAV--SSVACGASVGYAVTK 362
Score = 36.7 bits (81), Expect = 0.078
Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 1/67 (1%)
Frame = +2
Query: 254 TTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFV-KGLATKNVIQVACG 430
+++ACG A+ + G+ F+WG + QLG A + + K L + V+ V+ G
Sbjct: 348 SSVACGASVGYAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSG 407
Query: 431 AYHSVAL 451
H+V L
Sbjct: 408 GQHTVLL 414
Score = 31.5 bits (68), Expect = 2.9
Identities = 15/33 (45%), Positives = 20/33 (60%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE 200
VA+G H + L+ G LY+ G + GQLGR E
Sbjct: 177 VASGNDHLVMLTADGDLYTLGCGEQGQLGRVPE 209
>BC007300-1|AAH07300.1| 421|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 421
Score = 55.2 bits (127), Expect = 2e-07
Identities = 30/115 (26%), Positives = 56/115 (48%)
Frame = +2
Query: 269 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 448
G H++ + + GQ +S+G + G LG + + L K V+QV+ G H+ A
Sbjct: 75 GGMHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK-VVQVSAGDSHTAA 133
Query: 449 LTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
LT+ G ++ WG+ + L + K + + + VP+ + GN+H +L+
Sbjct: 134 LTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVASGNDHLVMLT 188
Score = 51.6 bits (118), Expect = 3e-06
Identities = 32/119 (26%), Positives = 55/119 (46%), Gaps = 1/119 (0%)
Frame = +2
Query: 269 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 448
G H++ +D G+ +S G G+LG GA + P + L V VACGA A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYA 359
Query: 449 LTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIAL-ITCGNNHTFVLSKSR 622
+T G +++WG + Q G + ++ + + + L ++ G HT +L K +
Sbjct: 360 VTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKDK 418
Score = 44.8 bits (101), Expect = 3e-04
Identities = 25/78 (32%), Positives = 38/78 (48%)
Frame = +2
Query: 272 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVAL 451
+ H E G + G +GQLG LG + ++ K ++V+Q G H+V L
Sbjct: 25 VSHRSHSTEPGLVLTLGQGDVGQLG--LGENVMERKKPALVSIPEDVVQAEAGGMHTVCL 82
Query: 452 TNSGDLYSWGANSYGQCG 505
+ SG +YS+G N G G
Sbjct: 83 SKSGQVYSFGCNDEGALG 100
Score = 42.7 bits (96), Expect = 0.001
Identities = 32/93 (34%), Positives = 45/93 (48%), Gaps = 4/93 (4%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGS--DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGA 433
++ G H+ A+ + G+ F WGS D+ G +G P V+ V++VA G
Sbjct: 124 VSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQ--LDVPVVKVASGN 181
Query: 434 YHSVALTNSGDLYSWGANSYGQCGL--ELYQTR 526
H V LT GDLY+ G GQ G EL+ R
Sbjct: 182 DHLVMLTADGDLYTLGCGEQGQLGRVPELFANR 214
Score = 41.1 bits (92), Expect = 0.004
Identities = 27/60 (45%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Frame = +3
Query: 57 KPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKN-PALVE 233
KP L E D +QA A G H++ LS SG +YS G ND G LGR T + + P VE
Sbjct: 59 KPALVSIPE-DVVQAEAGG-MHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE 116
Score = 41.1 bits (92), Expect = 0.004
Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 2/119 (1%)
Frame = +2
Query: 266 CGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGL--ATKNVIQVACGAYH 439
CG + AI G + +G + QLG G + P+ + +TK+ + + G +H
Sbjct: 247 CGAYFTFAISHEGHVYGFGLSNYHQLGTP-GTESCFIPQNLTSFKNSTKSWVGFSGGQHH 305
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSK 616
+V + + G YS G YG+ GL K IS L V + + CG + + ++K
Sbjct: 306 TVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPAV--SSVACGASVGYAVTK 362
Score = 36.7 bits (81), Expect = 0.078
Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 1/67 (1%)
Frame = +2
Query: 254 TTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFV-KGLATKNVIQVACG 430
+++ACG A+ + G+ F+WG + QLG A + + K L + V+ V+ G
Sbjct: 348 SSVACGASVGYAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSG 407
Query: 431 AYHSVAL 451
H+V L
Sbjct: 408 GQHTVLL 414
Score = 31.5 bits (68), Expect = 2.9
Identities = 15/33 (45%), Positives = 20/33 (60%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE 200
VA+G H + L+ G LY+ G + GQLGR E
Sbjct: 177 VASGNDHLVMLTADGDLYTLGCGEQGQLGRVPE 209
>AL513497-2|CAI22287.1| 421|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 421
Score = 55.2 bits (127), Expect = 2e-07
Identities = 30/115 (26%), Positives = 56/115 (48%)
Frame = +2
Query: 269 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 448
G H++ + + GQ +S+G + G LG + + L K V+QV+ G H+ A
Sbjct: 75 GGMHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK-VVQVSAGDSHTAA 133
Query: 449 LTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
LT+ G ++ WG+ + L + K + + + VP+ + GN+H +L+
Sbjct: 134 LTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVASGNDHLVMLT 188
Score = 51.6 bits (118), Expect = 3e-06
Identities = 32/119 (26%), Positives = 55/119 (46%), Gaps = 1/119 (0%)
Frame = +2
Query: 269 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 448
G H++ +D G+ +S G G+LG GA + P + L V VACGA A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYA 359
Query: 449 LTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIAL-ITCGNNHTFVLSKSR 622
+T G +++WG + Q G + ++ + + + L ++ G HT +L K +
Sbjct: 360 VTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKDK 418
Score = 44.8 bits (101), Expect = 3e-04
Identities = 25/78 (32%), Positives = 38/78 (48%)
Frame = +2
Query: 272 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVAL 451
+ H E G + G +GQLG LG + ++ K ++V+Q G H+V L
Sbjct: 25 VSHRSHSTEPGLVLTLGQGDVGQLG--LGENVMERKKPALVSIPEDVVQAEAGGMHTVCL 82
Query: 452 TNSGDLYSWGANSYGQCG 505
+ SG +YS+G N G G
Sbjct: 83 SKSGQVYSFGCNDEGALG 100
Score = 42.7 bits (96), Expect = 0.001
Identities = 32/93 (34%), Positives = 45/93 (48%), Gaps = 4/93 (4%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGS--DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGA 433
++ G H+ A+ + G+ F WGS D+ G +G P V+ V++VA G
Sbjct: 124 VSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQ--LDVPVVKVASGN 181
Query: 434 YHSVALTNSGDLYSWGANSYGQCGL--ELYQTR 526
H V LT GDLY+ G GQ G EL+ R
Sbjct: 182 DHLVMLTADGDLYTLGCGEQGQLGRVPELFANR 214
Score = 41.1 bits (92), Expect = 0.004
Identities = 27/60 (45%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Frame = +3
Query: 57 KPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKN-PALVE 233
KP L E D +QA A G H++ LS SG +YS G ND G LGR T + + P VE
Sbjct: 59 KPALVSIPE-DVVQAEAGG-MHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE 116
Score = 41.1 bits (92), Expect = 0.004
Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 2/119 (1%)
Frame = +2
Query: 266 CGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGL--ATKNVIQVACGAYH 439
CG + AI G + +G + QLG G + P+ + +TK+ + + G +H
Sbjct: 247 CGAYFTFAISHEGHVYGFGLSNYHQLGTP-GTESCFIPQNLTSFKNSTKSWVGFSGGQHH 305
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSK 616
+V + + G YS G YG+ GL K IS L V + + CG + + ++K
Sbjct: 306 TVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPAV--SSVACGASVGYAVTK 362
Score = 36.7 bits (81), Expect = 0.078
Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 1/67 (1%)
Frame = +2
Query: 254 TTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFV-KGLATKNVIQVACG 430
+++ACG A+ + G+ F+WG + QLG A + + K L + V+ V+ G
Sbjct: 348 SSVACGASVGYAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSG 407
Query: 431 AYHSVAL 451
H+V L
Sbjct: 408 GQHTVLL 414
Score = 31.5 bits (68), Expect = 2.9
Identities = 15/33 (45%), Positives = 20/33 (60%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE 200
VA+G H + L+ G LY+ G + GQLGR E
Sbjct: 177 VASGNDHLVMLTADGDLYTLGCGEQGQLGRVPE 209
>AF498924-1|AAM21072.1| 421|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 421
Score = 55.2 bits (127), Expect = 2e-07
Identities = 30/115 (26%), Positives = 56/115 (48%)
Frame = +2
Query: 269 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 448
G H++ + + GQ +S+G + G LG + + L K V+QV+ G H+ A
Sbjct: 75 GGMHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK-VVQVSAGDSHTAA 133
Query: 449 LTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLS 613
LT+ G ++ WG+ + L + K + + + VP+ + GN+H +L+
Sbjct: 134 LTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVASGNDHLVMLT 188
Score = 51.6 bits (118), Expect = 3e-06
Identities = 32/119 (26%), Positives = 55/119 (46%), Gaps = 1/119 (0%)
Frame = +2
Query: 269 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 448
G H++ +D G+ +S G G+LG GA + P + L V VACGA A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYA 359
Query: 449 LTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIAL-ITCGNNHTFVLSKSR 622
+T G +++WG + Q G + ++ + + + L ++ G HT +L K +
Sbjct: 360 VTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKDK 418
Score = 44.8 bits (101), Expect = 3e-04
Identities = 25/78 (32%), Positives = 38/78 (48%)
Frame = +2
Query: 272 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVAL 451
+ H E G + G +GQLG LG + ++ K ++V+Q G H+V L
Sbjct: 25 VSHRSHSTEPGLVLTLGQGDVGQLG--LGENVMERKKPALVSIPEDVVQAEAGGMHTVCL 82
Query: 452 TNSGDLYSWGANSYGQCG 505
+ SG +YS+G N G G
Sbjct: 83 SKSGQVYSFGCNDEGALG 100
Score = 42.7 bits (96), Expect = 0.001
Identities = 32/93 (34%), Positives = 45/93 (48%), Gaps = 4/93 (4%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGS--DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGA 433
++ G H+ A+ + G+ F WGS D+ G +G P V+ V++VA G
Sbjct: 124 VSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQ--LDVPVVKVASGN 181
Query: 434 YHSVALTNSGDLYSWGANSYGQCGL--ELYQTR 526
H V LT GDLY+ G GQ G EL+ R
Sbjct: 182 DHLVMLTADGDLYTLGCGEQGQLGRVPELFANR 214
Score = 41.1 bits (92), Expect = 0.004
Identities = 27/60 (45%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Frame = +3
Query: 57 KPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKN-PALVE 233
KP L E D +QA A G H++ LS SG +YS G ND G LGR T + + P VE
Sbjct: 59 KPALVSIPE-DVVQAEAGG-MHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE 116
Score = 41.1 bits (92), Expect = 0.004
Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 2/119 (1%)
Frame = +2
Query: 266 CGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGL--ATKNVIQVACGAYH 439
CG + AI G + +G + QLG G + P+ + +TK+ + + G +H
Sbjct: 247 CGAYFTFAISHEGHVYGFGLSNYHQLGTP-GTESCFIPQNLTSFKNSTKSWVGFSGGQHH 305
Query: 440 SVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTFVLSK 616
+V + + G YS G YG+ GL K IS L V + + CG + + ++K
Sbjct: 306 TVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPAV--SSVACGASVGYAVTK 362
Score = 36.7 bits (81), Expect = 0.078
Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 1/67 (1%)
Frame = +2
Query: 254 TTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFV-KGLATKNVIQVACG 430
+++ACG A+ + G+ F+WG + QLG A + + K L + V+ V+ G
Sbjct: 348 SSVACGASVGYAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSG 407
Query: 431 AYHSVAL 451
H+V L
Sbjct: 408 GQHTVLL 414
Score = 31.5 bits (68), Expect = 2.9
Identities = 15/33 (45%), Positives = 20/33 (60%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE 200
VA+G H + L+ G LY+ G + GQLGR E
Sbjct: 177 VASGNDHLVMLTADGDLYTLGCGEQGQLGRVPE 209
>BC040695-1|AAH40695.1| 358|Homo sapiens WBSCR16 protein protein.
Length = 358
Score = 54.0 bits (124), Expect = 5e-07
Identities = 35/107 (32%), Positives = 54/107 (50%), Gaps = 3/107 (2%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHA-QDKPKFVKGLATKN--VIQVACG 430
++CG HSL + + FS G++S GQ G + + + V + + V+QVACG
Sbjct: 179 VSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQVVQVACG 238
Query: 431 AYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPI 571
HS+ LT+ G++YS G + GQ GL Y + L GV +
Sbjct: 239 QDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNV 285
Score = 52.0 bits (119), Expect = 2e-06
Identities = 24/71 (33%), Positives = 39/71 (54%), Gaps = 3/71 (4%)
Frame = +2
Query: 410 VIQVACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTR---KCHLQHISSLIGVPIALI 580
V+QV+CG HS+ LT+ ++S G NSYGQCG ++ + + H H + +
Sbjct: 176 VLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQVVQV 235
Query: 581 TCGNNHTFVLS 613
CG +H+ L+
Sbjct: 236 ACGQDHSLFLT 246
Score = 46.4 bits (105), Expect = 1e-04
Identities = 28/80 (35%), Positives = 39/80 (48%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG HSL + + G+ +S G + GQ G K LA NVIQVA
Sbjct: 235 VACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDC 294
Query: 440 SVALTNSGDLYSWGANSYGQ 499
+A++ G L+ WG + Y Q
Sbjct: 295 CLAVSADGGLFGWGNSEYLQ 314
Score = 35.5 bits (78), Expect = 0.18
Identities = 15/29 (51%), Positives = 20/29 (68%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLG 188
VA G+ HSL+L++ G +YSCG GQ G
Sbjct: 235 VACGQDHSLFLTDKGEVYSCGWGADGQTG 263
Score = 33.1 bits (72), Expect = 0.96
Identities = 14/38 (36%), Positives = 22/38 (57%)
Frame = +3
Query: 81 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQ 194
+ + V+ G HSL L++ ++S GNN GQ GR+
Sbjct: 172 QETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRK 209
>BC032712-1|AAH32712.1| 454|Homo sapiens WBSCR16 protein protein.
Length = 454
Score = 54.0 bits (124), Expect = 5e-07
Identities = 35/107 (32%), Positives = 54/107 (50%), Gaps = 3/107 (2%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHA-QDKPKFVKGLATKN--VIQVACG 430
++CG HSL + + FS G++S GQ G + + + V + + V+QVACG
Sbjct: 179 VSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQVVQVACG 238
Query: 431 AYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPI 571
HS+ LT+ G++YS G + GQ GL Y + L GV +
Sbjct: 239 QDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNV 285
Score = 52.0 bits (119), Expect = 2e-06
Identities = 24/71 (33%), Positives = 39/71 (54%), Gaps = 3/71 (4%)
Frame = +2
Query: 410 VIQVACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTR---KCHLQHISSLIGVPIALI 580
V+QV+CG HS+ LT+ ++S G NSYGQCG ++ + + H H + +
Sbjct: 176 VLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQVVQV 235
Query: 581 TCGNNHTFVLS 613
CG +H+ L+
Sbjct: 236 ACGQDHSLFLT 246
Score = 46.4 bits (105), Expect = 1e-04
Identities = 28/80 (35%), Positives = 39/80 (48%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG HSL + + G+ +S G + GQ G K LA NVIQVA
Sbjct: 235 VACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDC 294
Query: 440 SVALTNSGDLYSWGANSYGQ 499
+A++ G L+ WG + Y Q
Sbjct: 295 CLAVSADGGLFGWGNSEYLQ 314
Score = 46.0 bits (104), Expect = 1e-04
Identities = 31/88 (35%), Positives = 42/88 (47%), Gaps = 6/88 (6%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK--PKFVKGLATKN----VIQVA 424
ACG ++ G F WG +G+ G NL A + P + GL N V ++
Sbjct: 342 ACGGTGCAVLNGEGHVFVWGYGILGK-GPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIR 400
Query: 425 CGAYHSVALTNSGDLYSWGANSYGQCGL 508
CG H ALTN G+L+ WG N G G+
Sbjct: 401 CGLSHFAALTNKGELFVWGKNIRGCLGI 428
Score = 35.5 bits (78), Expect = 0.18
Identities = 15/29 (51%), Positives = 20/29 (68%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLG 188
VA G+ HSL+L++ G +YSCG GQ G
Sbjct: 235 VACGQDHSLFLTDKGEVYSCGWGADGQTG 263
Score = 34.7 bits (76), Expect = 0.31
Identities = 19/72 (26%), Positives = 29/72 (40%)
Frame = +2
Query: 284 LAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSG 463
LA+ G F WG+ QL + + + P+ + V Q ACG L G
Sbjct: 296 LAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACGGTGCAVLNGEG 355
Query: 464 DLYSWGANSYGQ 499
++ WG G+
Sbjct: 356 HVFVWGYGILGK 367
Score = 33.1 bits (72), Expect = 0.96
Identities = 14/38 (36%), Positives = 22/38 (57%)
Frame = +3
Query: 81 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQ 194
+ + V+ G HSL L++ ++S GNN GQ GR+
Sbjct: 172 QETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRK 209
Score = 30.7 bits (66), Expect = 5.1
Identities = 13/29 (44%), Positives = 16/29 (55%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLG 346
I CGL H A+ G+ F WG + G LG
Sbjct: 399 IRCGLSHFAALTNKGELFVWGKNIRGCLG 427
>BC019008-1|AAH19008.1| 464|Homo sapiens Williams-Beuren syndrome
chromosome region 16 protein.
Length = 464
Score = 54.0 bits (124), Expect = 5e-07
Identities = 35/107 (32%), Positives = 54/107 (50%), Gaps = 3/107 (2%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHA-QDKPKFVKGLATKN--VIQVACG 430
++CG HSL + + FS G++S GQ G + + + V + + V+QVACG
Sbjct: 179 VSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQVVQVACG 238
Query: 431 AYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPI 571
HS+ LT+ G++YS G + GQ GL Y + L GV +
Sbjct: 239 QDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNV 285
Score = 52.0 bits (119), Expect = 2e-06
Identities = 24/71 (33%), Positives = 39/71 (54%), Gaps = 3/71 (4%)
Frame = +2
Query: 410 VIQVACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTR---KCHLQHISSLIGVPIALI 580
V+QV+CG HS+ LT+ ++S G NSYGQCG ++ + + H H + +
Sbjct: 176 VLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQVVQV 235
Query: 581 TCGNNHTFVLS 613
CG +H+ L+
Sbjct: 236 ACGQDHSLFLT 246
Score = 52.0 bits (119), Expect = 2e-06
Identities = 39/125 (31%), Positives = 59/125 (47%), Gaps = 6/125 (4%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK--PKFVKGLATKN----VIQVA 424
ACG ++ G F WG +G+ G NL A + P + GL N V ++
Sbjct: 342 ACGGTGCAVLNGEGHVFVWGYGILGK-GPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIR 400
Query: 425 CGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTF 604
CG H ALTN G+L+ WG N G G+ + + + ++ G P+ + CG +H
Sbjct: 401 CGLSHFAALTNKGELFVWGKNIRGCLGIGRLEDQ--YFPWRVTMPGEPVD-VACGVDHMV 457
Query: 605 VLSKS 619
L+KS
Sbjct: 458 TLAKS 462
Score = 46.4 bits (105), Expect = 1e-04
Identities = 28/80 (35%), Positives = 39/80 (48%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG HSL + + G+ +S G + GQ G K LA NVIQVA
Sbjct: 235 VACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDC 294
Query: 440 SVALTNSGDLYSWGANSYGQ 499
+A++ G L+ WG + Y Q
Sbjct: 295 CLAVSADGGLFGWGNSEYLQ 314
Score = 35.9 bits (79), Expect = 0.14
Identities = 23/67 (34%), Positives = 31/67 (46%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
I CGL H A+ G+ F WG + G LG +G +D+ + + VACG H
Sbjct: 399 IRCGLSHFAALTNKGELFVWGKNIRGCLG--IG-RLEDQYFPWRVTMPGEPVDVACGVDH 455
Query: 440 SVALTNS 460
V L S
Sbjct: 456 MVTLAKS 462
Score = 35.5 bits (78), Expect = 0.18
Identities = 15/29 (51%), Positives = 20/29 (68%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLG 188
VA G+ HSL+L++ G +YSCG GQ G
Sbjct: 235 VACGQDHSLFLTDKGEVYSCGWGADGQTG 263
Score = 34.7 bits (76), Expect = 0.31
Identities = 19/72 (26%), Positives = 29/72 (40%)
Frame = +2
Query: 284 LAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSG 463
LA+ G F WG+ QL + + + P+ + V Q ACG L G
Sbjct: 296 LAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACGGTGCAVLNGEG 355
Query: 464 DLYSWGANSYGQ 499
++ WG G+
Sbjct: 356 HVFVWGYGILGK 367
Score = 33.1 bits (72), Expect = 0.96
Identities = 14/38 (36%), Positives = 22/38 (57%)
Frame = +3
Query: 81 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQ 194
+ + V+ G HSL L++ ++S GNN GQ GR+
Sbjct: 172 QETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRK 209
>BC007823-1|AAH07823.1| 464|Homo sapiens Williams-Beuren syndrome
chromosome region 16 protein.
Length = 464
Score = 54.0 bits (124), Expect = 5e-07
Identities = 35/107 (32%), Positives = 54/107 (50%), Gaps = 3/107 (2%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHA-QDKPKFVKGLATKN--VIQVACG 430
++CG HSL + + FS G++S GQ G + + + V + + V+QVACG
Sbjct: 179 VSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQVVQVACG 238
Query: 431 AYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPI 571
HS+ LT+ G++YS G + GQ GL Y + L GV +
Sbjct: 239 QDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNV 285
Score = 52.0 bits (119), Expect = 2e-06
Identities = 24/71 (33%), Positives = 39/71 (54%), Gaps = 3/71 (4%)
Frame = +2
Query: 410 VIQVACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTR---KCHLQHISSLIGVPIALI 580
V+QV+CG HS+ LT+ ++S G NSYGQCG ++ + + H H + +
Sbjct: 176 VLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQVVQV 235
Query: 581 TCGNNHTFVLS 613
CG +H+ L+
Sbjct: 236 ACGQDHSLFLT 246
Score = 52.0 bits (119), Expect = 2e-06
Identities = 39/125 (31%), Positives = 59/125 (47%), Gaps = 6/125 (4%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK--PKFVKGLATKN----VIQVA 424
ACG ++ G F WG +G+ G NL A + P + GL N V ++
Sbjct: 342 ACGGTGCAVLNGEGHVFVWGYGILGK-GPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIR 400
Query: 425 CGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTF 604
CG H ALTN G+L+ WG N G G+ + + + ++ G P+ + CG +H
Sbjct: 401 CGLSHFAALTNKGELFVWGKNIRGCLGIGRLEDQ--YFPWRVTMPGEPVD-VACGVDHMV 457
Query: 605 VLSKS 619
L+KS
Sbjct: 458 TLAKS 462
Score = 46.4 bits (105), Expect = 1e-04
Identities = 28/80 (35%), Positives = 39/80 (48%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG HSL + + G+ +S G + GQ G K LA NVIQVA
Sbjct: 235 VACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDC 294
Query: 440 SVALTNSGDLYSWGANSYGQ 499
+A++ G L+ WG + Y Q
Sbjct: 295 CLAVSADGGLFGWGNSEYLQ 314
Score = 35.9 bits (79), Expect = 0.14
Identities = 23/67 (34%), Positives = 31/67 (46%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
I CGL H A+ G+ F WG + G LG +G +D+ + + VACG H
Sbjct: 399 IRCGLSHFAALTNKGELFVWGKNIRGCLG--IG-RLEDQYFPWRVTMPGEPVDVACGVDH 455
Query: 440 SVALTNS 460
V L S
Sbjct: 456 MVTLAKS 462
Score = 35.5 bits (78), Expect = 0.18
Identities = 15/29 (51%), Positives = 20/29 (68%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLG 188
VA G+ HSL+L++ G +YSCG GQ G
Sbjct: 235 VACGQDHSLFLTDKGEVYSCGWGADGQTG 263
Score = 34.7 bits (76), Expect = 0.31
Identities = 19/72 (26%), Positives = 29/72 (40%)
Frame = +2
Query: 284 LAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSG 463
LA+ G F WG+ QL + + + P+ + V Q ACG L G
Sbjct: 296 LAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACGGTGCAVLNGEG 355
Query: 464 DLYSWGANSYGQ 499
++ WG G+
Sbjct: 356 HVFVWGYGILGK 367
Score = 33.1 bits (72), Expect = 0.96
Identities = 14/38 (36%), Positives = 22/38 (57%)
Frame = +3
Query: 81 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQ 194
+ + V+ G HSL L++ ++S GNN GQ GR+
Sbjct: 172 QETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRK 209
>AF410455-1|AAM62304.1| 464|Homo sapiens RCC1-like G exchanging
factor-like protein protein.
Length = 464
Score = 54.0 bits (124), Expect = 5e-07
Identities = 35/107 (32%), Positives = 54/107 (50%), Gaps = 3/107 (2%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHA-QDKPKFVKGLATKN--VIQVACG 430
++CG HSL + + FS G++S GQ G + + + V + + V+QVACG
Sbjct: 179 VSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQVVQVACG 238
Query: 431 AYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPI 571
HS+ LT+ G++YS G + GQ GL Y + L GV +
Sbjct: 239 QDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNV 285
Score = 52.0 bits (119), Expect = 2e-06
Identities = 24/71 (33%), Positives = 39/71 (54%), Gaps = 3/71 (4%)
Frame = +2
Query: 410 VIQVACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTR---KCHLQHISSLIGVPIALI 580
V+QV+CG HS+ LT+ ++S G NSYGQCG ++ + + H H + +
Sbjct: 176 VLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQVVQV 235
Query: 581 TCGNNHTFVLS 613
CG +H+ L+
Sbjct: 236 ACGQDHSLFLT 246
Score = 52.0 bits (119), Expect = 2e-06
Identities = 39/125 (31%), Positives = 59/125 (47%), Gaps = 6/125 (4%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK--PKFVKGLATKN----VIQVA 424
ACG ++ G F WG +G+ G NL A + P + GL N V ++
Sbjct: 342 ACGGTGCAVLNGEGHVFVWGYGILGK-GPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIR 400
Query: 425 CGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGNNHTF 604
CG H ALTN G+L+ WG N G G+ + + + ++ G P+ + CG +H
Sbjct: 401 CGLSHFAALTNKGELFVWGKNIRGCLGIGRLEDQ--YFPWRVTMPGEPVD-VACGVDHMV 457
Query: 605 VLSKS 619
L+KS
Sbjct: 458 TLAKS 462
Score = 46.4 bits (105), Expect = 1e-04
Identities = 28/80 (35%), Positives = 39/80 (48%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
+ACG HSL + + G+ +S G + GQ G K LA NVIQVA
Sbjct: 235 VACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDC 294
Query: 440 SVALTNSGDLYSWGANSYGQ 499
+A++ G L+ WG + Y Q
Sbjct: 295 CLAVSADGGLFGWGNSEYLQ 314
Score = 35.9 bits (79), Expect = 0.14
Identities = 23/67 (34%), Positives = 31/67 (46%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 439
I CGL H A+ G+ F WG + G LG +G +D+ + + VACG H
Sbjct: 399 IRCGLSHFAALTNKGELFVWGKNIRGCLG--IG-RLEDQYFPWRVTMPGEPVDVACGVDH 455
Query: 440 SVALTNS 460
V L S
Sbjct: 456 MVTLAKS 462
Score = 35.5 bits (78), Expect = 0.18
Identities = 15/29 (51%), Positives = 20/29 (68%)
Frame = +3
Query: 102 VAAGEFHSLYLSNSGHLYSCGNNDVGQLG 188
VA G+ HSL+L++ G +YSCG GQ G
Sbjct: 235 VACGQDHSLFLTDKGEVYSCGWGADGQTG 263
Score = 34.7 bits (76), Expect = 0.31
Identities = 19/72 (26%), Positives = 29/72 (40%)
Frame = +2
Query: 284 LAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSG 463
LA+ G F WG+ QL + + + P+ + V Q ACG L G
Sbjct: 296 LAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACGGTGCAVLNGEG 355
Query: 464 DLYSWGANSYGQ 499
++ WG G+
Sbjct: 356 HVFVWGYGILGK 367
Score = 33.1 bits (72), Expect = 0.96
Identities = 14/38 (36%), Positives = 22/38 (57%)
Frame = +3
Query: 81 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQ 194
+ + V+ G HSL L++ ++S GNN GQ GR+
Sbjct: 172 QETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRK 209
>AL359257-2|CAI39759.1| 4640|Homo sapiens AC001226.5 protein.
Length = 4640
Score = 53.2 bits (122), Expect = 8e-07
Identities = 27/66 (40%), Positives = 40/66 (60%)
Frame = +2
Query: 413 IQVACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGN 592
+QV+CG +HSV L +GD+Y++G +GQ G +R C + +L G P +T G+
Sbjct: 905 VQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTL-VQALPG-PSTQVTAGS 962
Query: 593 NHTFVL 610
NHT VL
Sbjct: 963 NHTAVL 968
Score = 49.6 bits (113), Expect = 1e-05
Identities = 32/126 (25%), Positives = 59/126 (46%), Gaps = 5/126 (3%)
Frame = +2
Query: 245 LHNTTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVA 424
L ++CG HS+ + E G +++G GQLG+ +++ P V+ L + QV
Sbjct: 902 LRAVQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHG-DVNSRGCPTLVQALPGPST-QVT 959
Query: 425 CGAYHSVALTNSGDLYSWGANSYGQCG-----LELYQTRKCHLQHISSLIGVPIALITCG 589
G+ H+ L G ++++G+ S GQ G + + + + +I S G I
Sbjct: 960 AGSNHTAVLLMDGQVFTFGSFSKGQLGRPILDVPYWNAKPAPMPNIGSKYGRKATWIGAS 1019
Query: 590 NNHTFV 607
+ TF+
Sbjct: 1020 GDQTFL 1025
Score = 40.3 bits (90), Expect = 0.006
Identities = 35/123 (28%), Positives = 55/123 (44%), Gaps = 6/123 (4%)
Frame = +2
Query: 278 HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKP----KFVKGLATKNVIQVACGAYHSV 445
H+L + E G F GS S G+ G + + Q KP K +K + K V+ AC S
Sbjct: 555 HALLVAEDGSIFFTGSASKGEDGESTKSRRQSKPYKPKKIIK-MEGKIVVYTACNNGSSS 613
Query: 446 ALTNSGDLYSWGANSYGQCGLELYQTRKCH-LQHISSLIGVPIALITCGNNHTF-VLSKS 619
++ G+LY +G ++ L K H + ++ L+ G TF V +K
Sbjct: 614 VISKDGELYMFGKDAIYSDSSSLVTDLKGHFVTQVAMGKAHTCVLMKNGEVWTFGVNNKG 673
Query: 620 RCG 628
+CG
Sbjct: 674 QCG 676
Score = 38.3 bits (85), Expect = 0.026
Identities = 24/81 (29%), Positives = 38/81 (46%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 442
AC S I + G+ + +G D++ D V L V QVA G H+
Sbjct: 606 ACNNGSSSVISKDGELYMFGKDAI----------YSDSSSLVTDLKGHFVTQVAMGKAHT 655
Query: 443 VALTNSGDLYSWGANSYGQCG 505
L +G+++++G N+ GQCG
Sbjct: 656 CVLMKNGEVWTFGVNNKGQCG 676
>AL159158-1|CAI16842.1| 4640|Homo sapiens AC001226.5 protein.
Length = 4640
Score = 53.2 bits (122), Expect = 8e-07
Identities = 27/66 (40%), Positives = 40/66 (60%)
Frame = +2
Query: 413 IQVACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGN 592
+QV+CG +HSV L +GD+Y++G +GQ G +R C + +L G P +T G+
Sbjct: 905 VQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTL-VQALPG-PSTQVTAGS 962
Query: 593 NHTFVL 610
NHT VL
Sbjct: 963 NHTAVL 968
Score = 49.6 bits (113), Expect = 1e-05
Identities = 32/126 (25%), Positives = 59/126 (46%), Gaps = 5/126 (3%)
Frame = +2
Query: 245 LHNTTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVA 424
L ++CG HS+ + E G +++G GQLG+ +++ P V+ L + QV
Sbjct: 902 LRAVQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHG-DVNSRGCPTLVQALPGPST-QVT 959
Query: 425 CGAYHSVALTNSGDLYSWGANSYGQCG-----LELYQTRKCHLQHISSLIGVPIALITCG 589
G+ H+ L G ++++G+ S GQ G + + + + +I S G I
Sbjct: 960 AGSNHTAVLLMDGQVFTFGSFSKGQLGRPILDVPYWNAKPAPMPNIGSKYGRKATWIGAS 1019
Query: 590 NNHTFV 607
+ TF+
Sbjct: 1020 GDQTFL 1025
Score = 40.3 bits (90), Expect = 0.006
Identities = 35/123 (28%), Positives = 55/123 (44%), Gaps = 6/123 (4%)
Frame = +2
Query: 278 HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKP----KFVKGLATKNVIQVACGAYHSV 445
H+L + E G F GS S G+ G + + Q KP K +K + K V+ AC S
Sbjct: 555 HALLVAEDGSIFFTGSASKGEDGESTKSRRQSKPYKPKKIIK-MEGKIVVYTACNNGSSS 613
Query: 446 ALTNSGDLYSWGANSYGQCGLELYQTRKCH-LQHISSLIGVPIALITCGNNHTF-VLSKS 619
++ G+LY +G ++ L K H + ++ L+ G TF V +K
Sbjct: 614 VISKDGELYMFGKDAIYSDSSSLVTDLKGHFVTQVAMGKAHTCVLMKNGEVWTFGVNNKG 673
Query: 620 RCG 628
+CG
Sbjct: 674 QCG 676
Score = 38.3 bits (85), Expect = 0.026
Identities = 24/81 (29%), Positives = 38/81 (46%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 442
AC S I + G+ + +G D++ D V L V QVA G H+
Sbjct: 606 ACNNGSSSVISKDGELYMFGKDAI----------YSDSSSLVTDLKGHFVTQVAMGKAHT 655
Query: 443 VALTNSGDLYSWGANSYGQCG 505
L +G+++++G N+ GQCG
Sbjct: 656 CVLMKNGEVWTFGVNNKGQCG 676
>AL159154-1|CAH73736.1| 4640|Homo sapiens AC001226.5 protein.
Length = 4640
Score = 53.2 bits (122), Expect = 8e-07
Identities = 27/66 (40%), Positives = 40/66 (60%)
Frame = +2
Query: 413 IQVACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGN 592
+QV+CG +HSV L +GD+Y++G +GQ G +R C + +L G P +T G+
Sbjct: 905 VQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTL-VQALPG-PSTQVTAGS 962
Query: 593 NHTFVL 610
NHT VL
Sbjct: 963 NHTAVL 968
Score = 49.6 bits (113), Expect = 1e-05
Identities = 32/126 (25%), Positives = 59/126 (46%), Gaps = 5/126 (3%)
Frame = +2
Query: 245 LHNTTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVA 424
L ++CG HS+ + E G +++G GQLG+ +++ P V+ L + QV
Sbjct: 902 LRAVQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHG-DVNSRGCPTLVQALPGPST-QVT 959
Query: 425 CGAYHSVALTNSGDLYSWGANSYGQCG-----LELYQTRKCHLQHISSLIGVPIALITCG 589
G+ H+ L G ++++G+ S GQ G + + + + +I S G I
Sbjct: 960 AGSNHTAVLLMDGQVFTFGSFSKGQLGRPILDVPYWNAKPAPMPNIGSKYGRKATWIGAS 1019
Query: 590 NNHTFV 607
+ TF+
Sbjct: 1020 GDQTFL 1025
Score = 40.3 bits (90), Expect = 0.006
Identities = 35/123 (28%), Positives = 55/123 (44%), Gaps = 6/123 (4%)
Frame = +2
Query: 278 HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKP----KFVKGLATKNVIQVACGAYHSV 445
H+L + E G F GS S G+ G + + Q KP K +K + K V+ AC S
Sbjct: 555 HALLVAEDGSIFFTGSASKGEDGESTKSRRQSKPYKPKKIIK-MEGKIVVYTACNNGSSS 613
Query: 446 ALTNSGDLYSWGANSYGQCGLELYQTRKCH-LQHISSLIGVPIALITCGNNHTF-VLSKS 619
++ G+LY +G ++ L K H + ++ L+ G TF V +K
Sbjct: 614 VISKDGELYMFGKDAIYSDSSSLVTDLKGHFVTQVAMGKAHTCVLMKNGEVWTFGVNNKG 673
Query: 620 RCG 628
+CG
Sbjct: 674 QCG 676
Score = 38.3 bits (85), Expect = 0.026
Identities = 24/81 (29%), Positives = 38/81 (46%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 442
AC S I + G+ + +G D++ D V L V QVA G H+
Sbjct: 606 ACNNGSSSVISKDGELYMFGKDAI----------YSDSSSLVTDLKGHFVTQVAMGKAHT 655
Query: 443 VALTNSGDLYSWGANSYGQCG 505
L +G+++++G N+ GQCG
Sbjct: 656 CVLMKNGEVWTFGVNNKGQCG 676
>AF075587-1|AAC39928.1| 4641|Homo sapiens protein associated with Myc
protein.
Length = 4641
Score = 53.2 bits (122), Expect = 8e-07
Identities = 27/66 (40%), Positives = 40/66 (60%)
Frame = +2
Query: 413 IQVACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIGVPIALITCGN 592
+QV+CG +HSV L +GD+Y++G +GQ G +R C + +L G P +T G+
Sbjct: 905 VQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTL-VQALPG-PSTQVTAGS 962
Query: 593 NHTFVL 610
NHT VL
Sbjct: 963 NHTAVL 968
Score = 49.6 bits (113), Expect = 1e-05
Identities = 32/126 (25%), Positives = 59/126 (46%), Gaps = 5/126 (3%)
Frame = +2
Query: 245 LHNTTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVA 424
L ++CG HS+ + E G +++G GQLG+ +++ P V+ L + QV
Sbjct: 902 LRAVQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHG-DVNSRGCPTLVQALPGPST-QVT 959
Query: 425 CGAYHSVALTNSGDLYSWGANSYGQCG-----LELYQTRKCHLQHISSLIGVPIALITCG 589
G+ H+ L G ++++G+ S GQ G + + + + +I S G I
Sbjct: 960 AGSNHTAVLLMDGQVFTFGSFSKGQLGRPILDVPYWNAKPAPMPNIGSKYGRKATWIGAS 1019
Query: 590 NNHTFV 607
+ TF+
Sbjct: 1020 GDQTFL 1025
Score = 41.5 bits (93), Expect = 0.003
Identities = 34/122 (27%), Positives = 55/122 (45%), Gaps = 5/122 (4%)
Frame = +2
Query: 278 HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQD---KPKFVKGLATKNVIQVACGAYHSVA 448
H+L + E G F GS S G+ G ++ + Q KPK + + K V+ AC S
Sbjct: 555 HALLVAEDGSIFFTGSASKGEDGESIKSRRQSKPYKPKKIIKMEGKIVVYTACNNGSSSV 614
Query: 449 LTNSGDLYSWGANSYGQCGLELYQTRKCH-LQHISSLIGVPIALITCGNNHTF-VLSKSR 622
++ G+LY +G ++ L K H + ++ L+ G TF V +K +
Sbjct: 615 ISKDGELYMFGKDAIYSDSSSLVTDLKGHFVTQVAMGKAHTCVLMKNGEVWTFGVNNKGQ 674
Query: 623 CG 628
CG
Sbjct: 675 CG 676
Score = 38.3 bits (85), Expect = 0.026
Identities = 24/81 (29%), Positives = 38/81 (46%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 442
AC S I + G+ + +G D++ D V L V QVA G H+
Sbjct: 606 ACNNGSSSVISKDGELYMFGKDAI----------YSDSSSLVTDLKGHFVTQVAMGKAHT 655
Query: 443 VALTNSGDLYSWGANSYGQCG 505
L +G+++++G N+ GQCG
Sbjct: 656 CVLMKNGEVWTFGVNNKGQCG 676
>BC113826-1|AAI13827.1| 244|Homo sapiens RCCD1 protein protein.
Length = 244
Score = 48.4 bits (110), Expect = 2e-05
Identities = 23/61 (37%), Positives = 36/61 (59%)
Frame = +2
Query: 326 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCG 505
D GQLG+ A+ +P+ ++ L + +VA G +HSV ++ +GD+Y WG N GQ
Sbjct: 53 DPHGQLGHGT-LEAELEPRLLEALQGLVMAEVAAGGWHSVCVSETGDIYIWGWNESGQLA 111
Query: 506 L 508
L
Sbjct: 112 L 112
Score = 43.6 bits (98), Expect = 7e-04
Identities = 20/69 (28%), Positives = 38/69 (55%), Gaps = 2/69 (2%)
Frame = +2
Query: 407 NVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLELYQTRKCHLQHISSLIG--VPIALI 580
+ ++ +CG+ H+ +T +G+LY+WG YGQ G E T + + + + + +
Sbjct: 169 DAVKASCGSRHTAVVTRTGELYTWGWGKYGQLGHE-DTTSLDRPRRVEYFVDKQLQVKAV 227
Query: 581 TCGNNHTFV 607
TCG +T+V
Sbjct: 228 TCGPWNTYV 236
Score = 36.3 bits (80), Expect = 0.10
Identities = 18/62 (29%), Positives = 33/62 (53%), Gaps = 2/62 (3%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATK--NVIQVACGAY 436
+CG +H+ + G+ ++WG GQLG+ + D+P+ V+ K V V CG +
Sbjct: 174 SCGSRHTAVVTRTGELYTWGWGKYGQLGHE-DTTSLDRPRRVEYFVDKQLQVKAVTCGPW 232
Query: 437 HS 442
++
Sbjct: 233 NT 234
Score = 32.7 bits (71), Expect = 1.3
Identities = 17/50 (34%), Positives = 29/50 (58%)
Frame = +3
Query: 54 IKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTES 203
++P L + + + VAAG +HS+ +S +G +Y G N+ GQL T +
Sbjct: 67 LEPRLLEALQGLVMAEVAAGGWHSVCVSETGDIYIWGWNESGQLALPTRN 116
Score = 30.7 bits (66), Expect = 5.1
Identities = 18/54 (33%), Positives = 30/54 (55%)
Frame = +3
Query: 84 SDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKD 245
SD ++A + G H+ ++ +G LY+ G GQLG + ++ + P VE F D
Sbjct: 168 SDAVKA-SCGSRHTAVVTRTGELYTWGWGKYGQLGHE-DTTSLDRPRRVEYFVD 219
>DQ005634-1|AAY55907.1| 1196|Homo sapiens inhibitor of Bruton's
tyrosine kinase-beta protein.
Length = 1196
Score = 47.2 bits (107), Expect = 6e-05
Identities = 26/77 (33%), Positives = 41/77 (53%)
Frame = +2
Query: 278 HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTN 457
HS+ + + GQ ++ G G+LG+ P+ V+GL N QVA H+V LT
Sbjct: 188 HSVFLSQKGQVYTCGHGPGGRLGHG-DEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTE 246
Query: 458 SGDLYSWGANSYGQCGL 508
G +Y++G N + Q G+
Sbjct: 247 DGCVYTFGLNIFHQLGI 263
Score = 38.7 bits (86), Expect = 0.019
Identities = 23/65 (35%), Positives = 34/65 (52%), Gaps = 10/65 (15%)
Frame = +3
Query: 90 HIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG----------RQTESDNGKNPALVETF 239
+I+ V +FHS++LS G +Y+CG+ G+LG R E NG N + V
Sbjct: 178 YIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAA 237
Query: 240 KDCTI 254
KD T+
Sbjct: 238 KDHTV 242
>DQ005633-1|AAY55906.1| 1353|Homo sapiens inhibitor of Bruton's
tyrosine kinase-alpha protein.
Length = 1353
Score = 47.2 bits (107), Expect = 6e-05
Identities = 26/77 (33%), Positives = 41/77 (53%)
Frame = +2
Query: 278 HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTN 457
HS+ + + GQ ++ G G+LG+ P+ V+GL N QVA H+V LT
Sbjct: 188 HSVFLSQKGQVYTCGHGPGGRLGHG-DEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTE 246
Query: 458 SGDLYSWGANSYGQCGL 508
G +Y++G N + Q G+
Sbjct: 247 DGCVYTFGLNIFHQLGI 263
Score = 38.7 bits (86), Expect = 0.019
Identities = 23/65 (35%), Positives = 34/65 (52%), Gaps = 10/65 (15%)
Frame = +3
Query: 90 HIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG----------RQTESDNGKNPALVETF 239
+I+ V +FHS++LS G +Y+CG+ G+LG R E NG N + V
Sbjct: 178 YIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAA 237
Query: 240 KDCTI 254
KD T+
Sbjct: 238 KDHTV 242
>BC113698-1|AAI13699.1| 1353|Homo sapiens inhibitor of Bruton
agammaglobulinemia tyrosine kinase protein.
Length = 1353
Score = 47.2 bits (107), Expect = 6e-05
Identities = 26/77 (33%), Positives = 41/77 (53%)
Frame = +2
Query: 278 HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTN 457
HS+ + + GQ ++ G G+LG+ P+ V+GL N QVA H+V LT
Sbjct: 188 HSVFLSQKGQVYTCGHGPGGRLGHG-DEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTE 246
Query: 458 SGDLYSWGANSYGQCGL 508
G +Y++G N + Q G+
Sbjct: 247 DGCVYTFGLNIFHQLGI 263
Score = 38.7 bits (86), Expect = 0.019
Identities = 23/65 (35%), Positives = 34/65 (52%), Gaps = 10/65 (15%)
Frame = +3
Query: 90 HIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG----------RQTESDNGKNPALVETF 239
+I+ V +FHS++LS G +Y+CG+ G+LG R E NG N + V
Sbjct: 178 YIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAA 237
Query: 240 KDCTI 254
KD T+
Sbjct: 238 KDHTV 242
>BC113696-1|AAI13697.1| 1353|Homo sapiens inhibitor of Bruton
agammaglobulinemia tyrosine kinase protein.
Length = 1353
Score = 47.2 bits (107), Expect = 6e-05
Identities = 26/77 (33%), Positives = 41/77 (53%)
Frame = +2
Query: 278 HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTN 457
HS+ + + GQ ++ G G+LG+ P+ V+GL N QVA H+V LT
Sbjct: 188 HSVFLSQKGQVYTCGHGPGGRLGHG-DEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTE 246
Query: 458 SGDLYSWGANSYGQCGL 508
G +Y++G N + Q G+
Sbjct: 247 DGCVYTFGLNIFHQLGI 263
Score = 38.7 bits (86), Expect = 0.019
Identities = 23/65 (35%), Positives = 34/65 (52%), Gaps = 10/65 (15%)
Frame = +3
Query: 90 HIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG----------RQTESDNGKNPALVETF 239
+I+ V +FHS++LS G +Y+CG+ G+LG R E NG N + V
Sbjct: 178 YIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAA 237
Query: 240 KDCTI 254
KD T+
Sbjct: 238 KDHTV 242
>AL050333-2|CAI23416.1| 1187|Homo sapiens RP1-93K22.1 protein.
Length = 1187
Score = 47.2 bits (107), Expect = 6e-05
Identities = 26/77 (33%), Positives = 41/77 (53%)
Frame = +2
Query: 278 HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTN 457
HS+ + + GQ ++ G G+LG+ P+ V+GL N QVA H+V LT
Sbjct: 184 HSVFLSQKGQVYTCGHGPGGRLGHG-DEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTE 242
Query: 458 SGDLYSWGANSYGQCGL 508
G +Y++G N + Q G+
Sbjct: 243 DGCVYTFGLNIFHQLGI 259
Score = 38.7 bits (86), Expect = 0.019
Identities = 23/65 (35%), Positives = 34/65 (52%), Gaps = 10/65 (15%)
Frame = +3
Query: 90 HIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG----------RQTESDNGKNPALVETF 239
+I+ V +FHS++LS G +Y+CG+ G+LG R E NG N + V
Sbjct: 174 YIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAA 233
Query: 240 KDCTI 254
KD T+
Sbjct: 234 KDHTV 238
>AB037838-1|BAA92655.2| 1379|Homo sapiens KIAA1417 protein protein.
Length = 1379
Score = 47.2 bits (107), Expect = 6e-05
Identities = 26/77 (33%), Positives = 41/77 (53%)
Frame = +2
Query: 278 HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTN 457
HS+ + + GQ ++ G G+LG+ P+ V+GL N QVA H+V LT
Sbjct: 214 HSVFLSQKGQVYTCGHGPGGRLGHG-DEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTE 272
Query: 458 SGDLYSWGANSYGQCGL 508
G +Y++G N + Q G+
Sbjct: 273 DGCVYTFGLNIFHQLGI 289
Score = 38.7 bits (86), Expect = 0.019
Identities = 23/65 (35%), Positives = 34/65 (52%), Gaps = 10/65 (15%)
Frame = +3
Query: 90 HIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG----------RQTESDNGKNPALVETF 239
+I+ V +FHS++LS G +Y+CG+ G+LG R E NG N + V
Sbjct: 204 YIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAA 263
Query: 240 KDCTI 254
KD T+
Sbjct: 264 KDHTV 268
>AY650034-1|AAV66580.1| 110|Homo sapiens HECT and RCC1 containing
protein 4 isoform 4 protein.
Length = 110
Score = 43.6 bits (98), Expect = 7e-04
Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
Frame = +2
Query: 317 WGSDSMGQLG-NNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSY 493
WG+ S GQLG + +P+ K V V CG H+V + + G +Y+ G N
Sbjct: 4 WGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGCNDL 63
Query: 494 GQCGLE 511
GQ G E
Sbjct: 64 GQLGHE 69
Score = 41.5 bits (93), Expect = 0.003
Identities = 16/50 (32%), Positives = 33/50 (66%)
Frame = +3
Query: 45 DLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQ 194
++V++P S + + ++ V G H++++ + G +Y+CG ND+GQLG +
Sbjct: 20 EIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGCNDLGQLGHE 69
Score = 31.1 bits (67), Expect = 3.9
Identities = 13/42 (30%), Positives = 27/42 (64%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKF 385
+ CGL+H++ + + G ++ G + +GQLG+ ++ KP+F
Sbjct: 39 VGCGLRHTVFVLDDGTVYTCGCNDLGQLGHE---KSRKKPEF 77
>AY650032-1|AAV66578.1| 117|Homo sapiens HECT and RCC1 containing
protein 4 isoform 2 protein.
Length = 117
Score = 43.6 bits (98), Expect = 7e-04
Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
Frame = +2
Query: 317 WGSDSMGQLG-NNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSY 493
WG+ S GQLG + +P+ K V V CG H+V + + G +Y+ G N
Sbjct: 4 WGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGCNDL 63
Query: 494 GQCGLE 511
GQ G E
Sbjct: 64 GQLGHE 69
Score = 41.5 bits (93), Expect = 0.003
Identities = 16/50 (32%), Positives = 33/50 (66%)
Frame = +3
Query: 45 DLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQ 194
++V++P S + + ++ V G H++++ + G +Y+CG ND+GQLG +
Sbjct: 20 EIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGCNDLGQLGHE 69
Score = 31.1 bits (67), Expect = 3.9
Identities = 13/44 (29%), Positives = 28/44 (63%)
Frame = +2
Query: 260 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVK 391
+ CGL+H++ + + G ++ G + +GQLG+ ++ KP+ +K
Sbjct: 39 VGCGLRHTVFVLDDGTVYTCGCNDLGQLGHE---KSRKKPEILK 79
>AF225404-1|AAO27482.1| 259|Homo sapiens HERC2 protein.
Length = 259
Score = 38.7 bits (86), Expect = 0.019
Identities = 23/69 (33%), Positives = 34/69 (49%)
Frame = +2
Query: 302 GQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWG 481
G + WG + GQLG GA + P + LAT +Q+ G A+T G LY+ G
Sbjct: 127 GTIYGWGHNHRGQLGGIEGAKVK-VPTPCEALATLRPVQLIGGEQTLFAVTADGKLYATG 185
Query: 482 ANSYGQCGL 508
+ G+ G+
Sbjct: 186 YGAGGRLGI 194
Score = 36.7 bits (81), Expect = 0.078
Identities = 23/81 (28%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +2
Query: 269 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC--GAYHS 442
G Q A+ G+ ++ G + G+LG G + P ++ + + +VA G H
Sbjct: 168 GEQTLFAVTADGKLYATGYGAGGRLGIG-GTESVSTPTLLESIQHVFIKKVAVNSGGKHC 226
Query: 443 VALTNSGDLYSWGANSYGQCG 505
+AL++ G++YSWG G+ G
Sbjct: 227 LALSSEGEVYSWGEAEDGKLG 247
>BC067293-1|AAH67293.1| 580|Homo sapiens F-box protein 24 protein.
Length = 580
Score = 33.9 bits (74), Expect = 0.55
Identities = 20/68 (29%), Positives = 33/68 (48%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 442
A G H +DE+G+ F G++ GQLG D+ + + + I + CG HS
Sbjct: 363 ALGYNHLGLVDEFGRIFMQGNNRYGQLGT---GDKMDRGEPTQVCYLQRPITLWCGLNHS 419
Query: 443 VALTNSGD 466
+ L+ S +
Sbjct: 420 LVLSQSSE 427
Score = 29.9 bits (64), Expect = 8.9
Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 5/75 (6%)
Frame = +2
Query: 410 VIQVACGAYHSVALTNSGDLYSWGANSYGQCGL-----ELYQTRKCHLQHISSLIGVPIA 574
++ A G H + G ++ G N YGQ G T+ C+LQ PI
Sbjct: 359 ILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYLQR-------PIT 411
Query: 575 LITCGNNHTFVLSKS 619
L CG NH+ VLS+S
Sbjct: 412 L-WCGLNHSLVLSQS 425
>AC069281-1|AAP21863.1| 580|Homo sapiens unknown protein.
Length = 580
Score = 33.9 bits (74), Expect = 0.55
Identities = 20/68 (29%), Positives = 33/68 (48%)
Frame = +2
Query: 263 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 442
A G H +DE+G+ F G++ GQLG D+ + + + I + CG HS
Sbjct: 363 ALGYNHLGLVDEFGRIFMQGNNRYGQLGT---GDKMDRGEPTQVCYLQRPITLWCGLNHS 419
Query: 443 VALTNSGD 466
+ L+ S +
Sbjct: 420 LVLSQSSE 427
Score = 29.9 bits (64), Expect = 8.9
Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 5/75 (6%)
Frame = +2
Query: 410 VIQVACGAYHSVALTNSGDLYSWGANSYGQCGL-----ELYQTRKCHLQHISSLIGVPIA 574
++ A G H + G ++ G N YGQ G T+ C+LQ PI
Sbjct: 359 ILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYLQR-------PIT 411
Query: 575 LITCGNNHTFVLSKS 619
L CG NH+ VLS+S
Sbjct: 412 L-WCGLNHSLVLSQS 425
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 110,987,420
Number of Sequences: 237096
Number of extensions: 2477731
Number of successful extensions: 5086
Number of sequences better than 10.0: 101
Number of HSP's better than 10.0 without gapping: 3859
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4764
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7895240574
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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