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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= NV060654.seq
         (687 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AL096819-3|CAI21741.1|  932|Homo sapiens ER degradation enhancer...   115   1e-25
AF288393-1|AAG60613.1|  889|Homo sapiens C1orf22 protein.             115   1e-25
AL096819-2|CAI21740.1|  155|Homo sapiens ER degradation enhancer...    82   2e-15
AK023095-1|BAB14402.1|  155|Homo sapiens protein ( Homo sapiens ...    82   2e-15
BC105586-1|AAI05587.1|  242|Homo sapiens EDEM3 protein protein.        77   6e-14
D86967-1|BAA13203.2|  666|Homo sapiens KIAA0212 protein.               70   9e-12
BC019088-1|AAH19088.1|  657|Homo sapiens ER degradation enhancer...    70   9e-12
CR457266-1|CAG33547.1|  578|Homo sapiens C20orf31 protein.             67   5e-11
BC016184-1|AAH16184.1|  578|Homo sapiens ER degradation enhancer...    67   5e-11
BC001371-1|AAH01371.1|  578|Homo sapiens ER degradation enhancer...    67   5e-11
AL356652-1|CAH73763.1|  578|Homo sapiens ER degradation enhancer...    67   5e-11
AL135844-1|CAI19292.1|  578|Homo sapiens ER degradation enhancer...    67   5e-11
AK023931-1|BAB14731.1|  578|Homo sapiens protein ( Homo sapiens ...    67   5e-11
AK001645-1|BAA91806.1|  578|Homo sapiens protein ( Homo sapiens ...    67   5e-11
AY358580-1|AAQ88943.1|  541|Homo sapiens C20orf31 protein.             38   0.034
X74837-1|CAA52831.1|  625|Homo sapiens Man9-mannosidase protein.       36   0.18 
AL078600-1|CAB75695.2|  653|Homo sapiens mannosidase, alpha, cla...    36   0.18 
AL022722-2|CAI20315.1|  653|Homo sapiens mannosidase, alpha, cla...    36   0.18 
BC065827-1|AAH65827.1|  367|Homo sapiens MAN1A1 protein protein.       35   0.24 
BC063300-1|AAH63300.1|  641|Homo sapiens mannosidase, alpha, cla...    33   0.95 
AL358072-1|CAH71079.1|  641|Homo sapiens mannosidase, alpha, cla...    33   0.95 
AL157902-1|CAI22315.1|  641|Homo sapiens mannosidase, alpha, cla...    33   0.95 
AF053621-1|AAC26200.1|  358|Homo sapiens alpha 1,2-mannosidase I...    33   0.95 
AF027156-1|AAC26169.1|  641|Homo sapiens alpha 1,2-mannosidase I...    33   0.95 
AK023308-1|BAB14518.1|  618|Homo sapiens protein ( Homo sapiens ...    33   1.3  
BC006079-1|AAH06079.1|  699|Homo sapiens mannosidase, alpha, cla...    31   3.8  
BC002953-1|AAH02953.1|  699|Homo sapiens mannosidase, alpha, cla...    31   3.8  
AY358465-1|AAQ88830.1|  699|Homo sapiens MAN1B1 protein.               31   3.8  
AL929554-19|CAH72887.1|  699|Homo sapiens mannosidase, alpha, cl...    31   3.8  
AL807752-35|CAI12781.1|  699|Homo sapiens mannosidase, alpha, cl...    31   3.8  
AF148509-1|AAF03215.1|  699|Homo sapiens alpha 1,2-mannosidase p...    31   3.8  
AF145732-1|AAD45504.1|  663|Homo sapiens endoplasmic reticulum a...    31   3.8  

>AL096819-3|CAI21741.1|  932|Homo sapiens ER degradation enhancer,
           mannosidase alpha-like 3 protein.
          Length = 932

 Score =  115 bits (277), Expect = 1e-25
 Identities = 62/133 (46%), Positives = 77/133 (57%)
 Frame = +1

Query: 274 MSKAERLSLRDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSRGDMDDALGNF 453
           MS+ E+  L ++  +MF HAY  YME+AYPADELMPL+C+GR  G  PSRGD+DDALG F
Sbjct: 44  MSREEKQKLGNQVLEMFDHAYGNYMEHAYPADELMPLTCRGRVRGQEPSRGDVDDALGKF 103

Query: 454 XXXXXXXXXXXXXMGDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLAE 633
                        +    +       + +   L   +VVSVFETNIR+LGGLL  H LA 
Sbjct: 104 SLTLIDSLDTLVVLNKTKEFEDAVRKVLRDVNLDNDVVVSVFETNIRVLGGLLGGHSLAI 163

Query: 634 TLKSDIPLXQWYN 672
            LK      QWYN
Sbjct: 164 MLKEKGEYMQWYN 176


>AF288393-1|AAG60613.1|  889|Homo sapiens C1orf22 protein.
          Length = 889

 Score =  115 bits (277), Expect = 1e-25
 Identities = 62/133 (46%), Positives = 77/133 (57%)
 Frame = +1

Query: 274 MSKAERLSLRDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSRGDMDDALGNF 453
           MS+ E+  L ++  +MF HAY  YME+AYPADELMPL+C+GR  G  PSRGD+DDALG F
Sbjct: 1   MSREEKQKLGNQVLEMFDHAYGNYMEHAYPADELMPLTCRGRVRGQEPSRGDVDDALGKF 60

Query: 454 XXXXXXXXXXXXXMGDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLAE 633
                        +    +       + +   L   +VVSVFETNIR+LGGLL  H LA 
Sbjct: 61  SLTLIDSLDTLVVLNKTKEFEDAVRKVLRDVNLDNDVVVSVFETNIRVLGGLLGGHSLAI 120

Query: 634 TLKSDIPLXQWYN 672
            LK      QWYN
Sbjct: 121 MLKEKGEYMQWYN 133


>AL096819-2|CAI21740.1|  155|Homo sapiens ER degradation enhancer,
           mannosidase alpha-like 3 protein.
          Length = 155

 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 37/60 (61%), Positives = 46/60 (76%)
 Frame = +1

Query: 274 MSKAERLSLRDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSRGDMDDALGNF 453
           MS+ E+  L ++  +MF HAY  YME+AYPADELMPL+C+GR  G  PSRGD+DDALG F
Sbjct: 44  MSREEKQKLGNQVLEMFDHAYGNYMEHAYPADELMPLTCRGRVRGQEPSRGDVDDALGKF 103


>AK023095-1|BAB14402.1|  155|Homo sapiens protein ( Homo sapiens
           cDNA FLJ13033 fis, clone NT2RP3001126. ).
          Length = 155

 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 37/60 (61%), Positives = 46/60 (76%)
 Frame = +1

Query: 274 MSKAERLSLRDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSRGDMDDALGNF 453
           MS+ E+  L ++  +MF HAY  YME+AYPADELMPL+C+GR  G  PSRGD+DDALG F
Sbjct: 44  MSREEKQKLGNQVLEMFDHAYGNYMEHAYPADELMPLTCRGRVRGQEPSRGDVDDALGKF 103


>BC105586-1|AAI05587.1|  242|Homo sapiens EDEM3 protein protein.
          Length = 242

 Score = 77.0 bits (181), Expect = 6e-14
 Identities = 43/99 (43%), Positives = 52/99 (52%)
 Frame = +1

Query: 376 MPLSCKGRWXGITPSRGDMDDALGNFXXXXXXXXXXXXXMGDFSDLIMQSNSL*KMSLLT 555
           MPL+C+GR  G  PSRGD+DDALG F             +    +       + +   L 
Sbjct: 1   MPLTCRGRVRGQEPSRGDVDDALGKFSLTLIDSLDTLVVLNKTKEFEDAVRKVLRDVNLD 60

Query: 556 KILVVSVFETNIRMLGGLLSAHVLAETLKSDIPLXQWYN 672
             +VVSVFETNIR+LGGLL  H LA  LK      QWYN
Sbjct: 61  NDVVVSVFETNIRVLGGLLGGHSLAIMLKEKGEYMQWYN 99


>D86967-1|BAA13203.2|  666|Homo sapiens KIAA0212 protein.
          Length = 666

 Score = 69.7 bits (163), Expect = 9e-12
 Identities = 41/112 (36%), Positives = 55/112 (49%), Gaps = 1/112 (0%)
 Frame = +1

Query: 289 RLSLRDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGI-TPSRGDMDDALGNFXXXX 465
           R  +RD +R MF   Y  YM +A+P DEL P+ C+GR      PS  +++D LGN+    
Sbjct: 136 RAQMRDLARGMFVFGYDNYMAHAFPQDELNPIHCRGRGPDRGDPSNLNINDVLGNYSLTL 195

Query: 466 XXXXXXXXXMGDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAH 621
                    MG+ S+       +       K   V VFE  IR+LG LLSAH
Sbjct: 196 VDALDTLAIMGNSSEFQKAVKLVINTVSFDKDSTVQVFEATIRVLGSLLSAH 247


>BC019088-1|AAH19088.1|  657|Homo sapiens ER degradation enhancer,
           mannosidase alpha-like 1 protein.
          Length = 657

 Score = 69.7 bits (163), Expect = 9e-12
 Identities = 41/112 (36%), Positives = 55/112 (49%), Gaps = 1/112 (0%)
 Frame = +1

Query: 289 RLSLRDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGI-TPSRGDMDDALGNFXXXX 465
           R  +RD +R MF   Y  YM +A+P DEL P+ C+GR      PS  +++D LGN+    
Sbjct: 127 RAQMRDLARGMFVFGYDNYMAHAFPQDELNPIHCRGRGPDRGDPSNLNINDVLGNYSLTL 186

Query: 466 XXXXXXXXXMGDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAH 621
                    MG+ S+       +       K   V VFE  IR+LG LLSAH
Sbjct: 187 VDALDTLAIMGNSSEFQKAVKLVINTVSFDKDSTVQVFEATIRVLGSLLSAH 238


>CR457266-1|CAG33547.1|  578|Homo sapiens C20orf31 protein.
          Length = 578

 Score = 67.3 bits (157), Expect = 5e-11
 Identities = 41/111 (36%), Positives = 57/111 (51%)
 Frame = +1

Query: 301 RDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSRGDMDDALGNFXXXXXXXXX 480
           R+  + MFYHAY +Y+ENA+P DEL PL+C G             D  G+F         
Sbjct: 36  RERVKAMFYHAYDSYLENAFPFDELRPLTCDGH------------DTWGSFSLTLIDALD 83

Query: 481 XXXXMGDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLAE 633
               +G+ S+       L         +  SVFETNIR++GGLLSAH+L++
Sbjct: 84  TLLILGNVSEFQRVVEVLQDSVDFDIDVNASVFETNIRVVGGLLSAHLLSK 134


>BC016184-1|AAH16184.1|  578|Homo sapiens ER degradation enhancer,
           mannosidase alpha-like 2 protein.
          Length = 578

 Score = 67.3 bits (157), Expect = 5e-11
 Identities = 41/111 (36%), Positives = 57/111 (51%)
 Frame = +1

Query: 301 RDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSRGDMDDALGNFXXXXXXXXX 480
           R+  + MFYHAY +Y+ENA+P DEL PL+C G             D  G+F         
Sbjct: 36  RERVKAMFYHAYDSYLENAFPFDELRPLTCDGH------------DTWGSFSLTLIDALD 83

Query: 481 XXXXMGDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLAE 633
               +G+ S+       L         +  SVFETNIR++GGLLSAH+L++
Sbjct: 84  TLLILGNVSEFQRVVEVLQDSVDFDIDVNASVFETNIRVVGGLLSAHLLSK 134


>BC001371-1|AAH01371.1|  578|Homo sapiens ER degradation enhancer,
           mannosidase alpha-like 2 protein.
          Length = 578

 Score = 67.3 bits (157), Expect = 5e-11
 Identities = 41/111 (36%), Positives = 57/111 (51%)
 Frame = +1

Query: 301 RDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSRGDMDDALGNFXXXXXXXXX 480
           R+  + MFYHAY +Y+ENA+P DEL PL+C G             D  G+F         
Sbjct: 36  RERVKAMFYHAYDSYLENAFPFDELRPLTCDGH------------DTWGSFSLTLIDALD 83

Query: 481 XXXXMGDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLAE 633
               +G+ S+       L         +  SVFETNIR++GGLLSAH+L++
Sbjct: 84  TLLILGNVSEFQRVVEVLQDSVDFDIDVNASVFETNIRVVGGLLSAHLLSK 134


>AL356652-1|CAH73763.1|  578|Homo sapiens ER degradation enhancer,
           mannosidase alpha-like 2 protein.
          Length = 578

 Score = 67.3 bits (157), Expect = 5e-11
 Identities = 41/111 (36%), Positives = 57/111 (51%)
 Frame = +1

Query: 301 RDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSRGDMDDALGNFXXXXXXXXX 480
           R+  + MFYHAY +Y+ENA+P DEL PL+C G             D  G+F         
Sbjct: 36  RERVKAMFYHAYDSYLENAFPFDELRPLTCDGH------------DTWGSFSLTLIDALD 83

Query: 481 XXXXMGDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLAE 633
               +G+ S+       L         +  SVFETNIR++GGLLSAH+L++
Sbjct: 84  TLLILGNVSEFQRVVEVLQDSVDFDIDVNASVFETNIRVVGGLLSAHLLSK 134


>AL135844-1|CAI19292.1|  578|Homo sapiens ER degradation enhancer,
           mannosidase alpha-like 2 protein.
          Length = 578

 Score = 67.3 bits (157), Expect = 5e-11
 Identities = 41/111 (36%), Positives = 57/111 (51%)
 Frame = +1

Query: 301 RDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSRGDMDDALGNFXXXXXXXXX 480
           R+  + MFYHAY +Y+ENA+P DEL PL+C G             D  G+F         
Sbjct: 36  RERVKAMFYHAYDSYLENAFPFDELRPLTCDGH------------DTWGSFSLTLIDALD 83

Query: 481 XXXXMGDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLAE 633
               +G+ S+       L         +  SVFETNIR++GGLLSAH+L++
Sbjct: 84  TLLILGNVSEFQRVVEVLQDSVDFDIDVNASVFETNIRVVGGLLSAHLLSK 134


>AK023931-1|BAB14731.1|  578|Homo sapiens protein ( Homo sapiens
           cDNA FLJ13869 fis, clone THYRO1001287, weakly similar to
           MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE (EC
           3.2.1.113). ).
          Length = 578

 Score = 67.3 bits (157), Expect = 5e-11
 Identities = 41/111 (36%), Positives = 57/111 (51%)
 Frame = +1

Query: 301 RDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSRGDMDDALGNFXXXXXXXXX 480
           R+  + MFYHAY +Y+ENA+P DEL PL+C G             D  G+F         
Sbjct: 36  RERVKAMFYHAYDSYLENAFPFDELRPLTCDGH------------DTWGSFSLTLIDALD 83

Query: 481 XXXXMGDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLAE 633
               +G+ S+       L         +  SVFETNIR++GGLLSAH+L++
Sbjct: 84  TLLILGNVSEFQRVVEVLQDSVDFDIDVNASVFETNIRVVGGLLSAHLLSK 134


>AK001645-1|BAA91806.1|  578|Homo sapiens protein ( Homo sapiens
           cDNA FLJ10783 fis, clone NT2RP4000417, weakly similar to
           MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE (EC
           3.2.1.113). ).
          Length = 578

 Score = 67.3 bits (157), Expect = 5e-11
 Identities = 41/111 (36%), Positives = 57/111 (51%)
 Frame = +1

Query: 301 RDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSRGDMDDALGNFXXXXXXXXX 480
           R+  + MFYHAY +Y+ENA+P DEL PL+C G             D  G+F         
Sbjct: 36  RERVKAMFYHAYDSYLENAFPFDELRPLTCDGH------------DTWGSFSLTLIDALD 83

Query: 481 XXXXMGDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLAE 633
               +G+ S+       L         +  SVFETNIR++GGLLSAH+L++
Sbjct: 84  TLLILGNVSEFQRVVEVLQDSVDFDIDVNASVFETNIRVVGGLLSAHLLSK 134


>AY358580-1|AAQ88943.1|  541|Homo sapiens C20orf31 protein.
          Length = 541

 Score = 37.9 bits (84), Expect = 0.034
 Identities = 16/21 (76%), Positives = 21/21 (100%)
 Frame = +1

Query: 571 SVFETNIRMLGGLLSAHVLAE 633
           SVFETNIR++GGLLSAH+L++
Sbjct: 77  SVFETNIRVVGGLLSAHLLSK 97


>X74837-1|CAA52831.1|  625|Homo sapiens Man9-mannosidase protein.
          Length = 625

 Score = 35.5 bits (78), Expect = 0.18
 Identities = 31/111 (27%), Positives = 50/111 (45%), Gaps = 1/111 (0%)
 Frame = +1

Query: 301 RDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSRGDMDDALGNFXXXXXXXXX 480
           R + ++M  HA++ Y   A+  +EL P+S KG         G      GN          
Sbjct: 168 RAKIKEMMKHAWNNYKGYAWGLNELKPIS-KG---------GHSSSLFGNIKGATIVDAL 217

Query: 481 XXXXMGDFSDLIMQSNSL*KMSLLTKILV-VSVFETNIRMLGGLLSAHVLA 630
               + +      ++ S  + +L   +   +SVFE NIR +GGLLSA+ L+
Sbjct: 218 DTLFIMEMKHEFEEAKSWVEENLDFNVNAEISVFEVNIRFVGGLLSAYYLS 268


>AL078600-1|CAB75695.2|  653|Homo sapiens mannosidase, alpha, class
           1A, member 1 protein.
          Length = 653

 Score = 35.5 bits (78), Expect = 0.18
 Identities = 31/111 (27%), Positives = 50/111 (45%), Gaps = 1/111 (0%)
 Frame = +1

Query: 301 RDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSRGDMDDALGNFXXXXXXXXX 480
           R + ++M  HA++ Y   A+  +EL P+S KG         G      GN          
Sbjct: 196 RAKIKEMMKHAWNNYKGYAWGLNELKPIS-KG---------GHSSSLFGNIKGATIVDAL 245

Query: 481 XXXXMGDFSDLIMQSNSL*KMSLLTKILV-VSVFETNIRMLGGLLSAHVLA 630
               + +      ++ S  + +L   +   +SVFE NIR +GGLLSA+ L+
Sbjct: 246 DTLFIMEMKHEFEEAKSWVEENLDFNVNAEISVFEVNIRFVGGLLSAYYLS 296


>AL022722-2|CAI20315.1|  653|Homo sapiens mannosidase, alpha, class
           1A, member 1 protein.
          Length = 653

 Score = 35.5 bits (78), Expect = 0.18
 Identities = 31/111 (27%), Positives = 50/111 (45%), Gaps = 1/111 (0%)
 Frame = +1

Query: 301 RDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSRGDMDDALGNFXXXXXXXXX 480
           R + ++M  HA++ Y   A+  +EL P+S KG         G      GN          
Sbjct: 196 RAKIKEMMKHAWNNYKGYAWGLNELKPIS-KG---------GHSSSLFGNIKGATIVDAL 245

Query: 481 XXXXMGDFSDLIMQSNSL*KMSLLTKILV-VSVFETNIRMLGGLLSAHVLA 630
               + +      ++ S  + +L   +   +SVFE NIR +GGLLSA+ L+
Sbjct: 246 DTLFIMEMKHEFEEAKSWVEENLDFNVNAEISVFEVNIRFVGGLLSAYYLS 296


>BC065827-1|AAH65827.1|  367|Homo sapiens MAN1A1 protein protein.
          Length = 367

 Score = 35.1 bits (77), Expect = 0.24
 Identities = 31/106 (29%), Positives = 47/106 (44%), Gaps = 1/106 (0%)
 Frame = +1

Query: 316 QMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSRGDMDDALGNFXXXXXXXXXXXXXM 495
           QM  HA++ Y   A+  +EL P+S KG         G      GN              +
Sbjct: 224 QMMKHAWNNYKGYAWGLNELKPIS-KG---------GHSSSLFGNIKGATIVDALDTLFI 273

Query: 496 GDFSDLIMQSNSL*KMSLLTKILV-VSVFETNIRMLGGLLSAHVLA 630
            +      ++ S  + +L   +   +SVFE NIR +GGLLSA+ L+
Sbjct: 274 MEMKHEFEEAKSWVEENLDFNVNAEISVFEVNIRFVGGLLSAYYLS 319


>BC063300-1|AAH63300.1|  641|Homo sapiens mannosidase, alpha, class
           1A, member 2 protein.
          Length = 641

 Score = 33.1 bits (72), Expect = 0.95
 Identities = 32/113 (28%), Positives = 47/113 (41%), Gaps = 3/113 (2%)
 Frame = +1

Query: 301 RDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSR---GDMDDALGNFXXXXXX 471
           R++ ++M  HA+  Y    +  +EL P++ KG    I  S      + DAL         
Sbjct: 181 REKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLH 240

Query: 472 XXXXXXXMGDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLA 630
                       +L    NS            VSVFE NIR +GGLL+A+ L+
Sbjct: 241 DEFLDGQRWIEDNLDFSVNS-----------EVSVFEVNIRFIGGLLAAYYLS 282


>AL358072-1|CAH71079.1|  641|Homo sapiens mannosidase, alpha, class
           1A, member 2 protein.
          Length = 641

 Score = 33.1 bits (72), Expect = 0.95
 Identities = 32/113 (28%), Positives = 47/113 (41%), Gaps = 3/113 (2%)
 Frame = +1

Query: 301 RDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSR---GDMDDALGNFXXXXXX 471
           R++ ++M  HA+  Y    +  +EL P++ KG    I  S      + DAL         
Sbjct: 181 REKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLH 240

Query: 472 XXXXXXXMGDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLA 630
                       +L    NS            VSVFE NIR +GGLL+A+ L+
Sbjct: 241 DEFLDGQRWIEDNLDFSVNS-----------EVSVFEVNIRFIGGLLAAYYLS 282


>AL157902-1|CAI22315.1|  641|Homo sapiens mannosidase, alpha, class
           1A, member 2 protein.
          Length = 641

 Score = 33.1 bits (72), Expect = 0.95
 Identities = 32/113 (28%), Positives = 47/113 (41%), Gaps = 3/113 (2%)
 Frame = +1

Query: 301 RDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSR---GDMDDALGNFXXXXXX 471
           R++ ++M  HA+  Y    +  +EL P++ KG    I  S      + DAL         
Sbjct: 181 REKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLH 240

Query: 472 XXXXXXXMGDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLA 630
                       +L    NS            VSVFE NIR +GGLL+A+ L+
Sbjct: 241 DEFLDGQRWIEDNLDFSVNS-----------EVSVFEVNIRFIGGLLAAYYLS 282


>AF053621-1|AAC26200.1|  358|Homo sapiens alpha 1,2-mannosidase IB
           protein.
          Length = 358

 Score = 33.1 bits (72), Expect = 0.95
 Identities = 32/113 (28%), Positives = 47/113 (41%), Gaps = 3/113 (2%)
 Frame = +1

Query: 301 RDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSR---GDMDDALGNFXXXXXX 471
           R++ ++M  HA+  Y    +  +EL P++ KG    I  S      + DAL         
Sbjct: 181 REKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLH 240

Query: 472 XXXXXXXMGDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLA 630
                       +L    NS            VSVFE NIR +GGLL+A+ L+
Sbjct: 241 DEFLDGQRWIEDNLDFSVNS-----------EVSVFEVNIRFIGGLLAAYYLS 282


>AF027156-1|AAC26169.1|  641|Homo sapiens alpha 1,2-mannosidase IB
           protein.
          Length = 641

 Score = 33.1 bits (72), Expect = 0.95
 Identities = 32/113 (28%), Positives = 47/113 (41%), Gaps = 3/113 (2%)
 Frame = +1

Query: 301 RDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSR---GDMDDALGNFXXXXXX 471
           R++ ++M  HA+  Y    +  +EL P++ KG    I  S      + DAL         
Sbjct: 181 REKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLH 240

Query: 472 XXXXXXXMGDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLA 630
                       +L    NS            VSVFE NIR +GGLL+A+ L+
Sbjct: 241 DEFLDGQRWIEDNLDFSVNS-----------EVSVFEVNIRFIGGLLAAYYLS 282


>AK023308-1|BAB14518.1|  618|Homo sapiens protein ( Homo sapiens
           cDNA FLJ13246 fis, clone OVARC1000682, highly similar to
           PROCESSING ALPHA-1,2-MANNOSIDASE (EC 3.2.1.-). ).
          Length = 618

 Score = 32.7 bits (71), Expect = 1.3
 Identities = 14/21 (66%), Positives = 18/21 (85%)
 Frame = +1

Query: 568 VSVFETNIRMLGGLLSAHVLA 630
           VSVFE NIR +GGLL+A+ L+
Sbjct: 52  VSVFEVNIRFIGGLLAAYYLS 72


>BC006079-1|AAH06079.1|  699|Homo sapiens mannosidase, alpha, class
           1B, member 1 protein.
          Length = 699

 Score = 31.1 bits (67), Expect = 3.8
 Identities = 30/105 (28%), Positives = 48/105 (45%), Gaps = 1/105 (0%)
 Frame = +1

Query: 319 MFYHAYHAYMENAYPADELMPLSCK-GRWXGITPSRGDMDDALGNFXXXXXXXXXXXXXM 495
           +F HA+  Y + A+  DEL P+S     W G+  +  D  D +                +
Sbjct: 256 VFLHAWKGYRKFAWGHDELKPVSRSFSEWFGLGLTLIDALDTM--------------WIL 301

Query: 496 GDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLA 630
           G   +       + K     K + V++FE+ IR+LGGLLSA+ L+
Sbjct: 302 GLRKEFEEARKWVSKKLHFEKDVDVNLFESTIRILGGLLSAYHLS 346


>BC002953-1|AAH02953.1|  699|Homo sapiens mannosidase, alpha, class
           1B, member 1 protein.
          Length = 699

 Score = 31.1 bits (67), Expect = 3.8
 Identities = 30/105 (28%), Positives = 48/105 (45%), Gaps = 1/105 (0%)
 Frame = +1

Query: 319 MFYHAYHAYMENAYPADELMPLSCK-GRWXGITPSRGDMDDALGNFXXXXXXXXXXXXXM 495
           +F HA+  Y + A+  DEL P+S     W G+  +  D  D +                +
Sbjct: 256 VFLHAWKGYRKFAWGHDELKPVSRSFSEWFGLGLTLIDALDTM--------------WIL 301

Query: 496 GDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLA 630
           G   +       + K     K + V++FE+ IR+LGGLLSA+ L+
Sbjct: 302 GLRKEFEEARKWVSKKLHFEKDVDVNLFESTIRILGGLLSAYHLS 346


>AY358465-1|AAQ88830.1|  699|Homo sapiens MAN1B1 protein.
          Length = 699

 Score = 31.1 bits (67), Expect = 3.8
 Identities = 30/105 (28%), Positives = 48/105 (45%), Gaps = 1/105 (0%)
 Frame = +1

Query: 319 MFYHAYHAYMENAYPADELMPLSCK-GRWXGITPSRGDMDDALGNFXXXXXXXXXXXXXM 495
           +F HA+  Y + A+  DEL P+S     W G+  +  D  D +                +
Sbjct: 256 VFLHAWKGYRKFAWGHDELKPVSRSFSEWFGLGLTLIDALDTM--------------WIL 301

Query: 496 GDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLA 630
           G   +       + K     K + V++FE+ IR+LGGLLSA+ L+
Sbjct: 302 GLRKEFEEARKWVSKKLHFEKDVDVNLFESTIRILGGLLSAYHLS 346


>AL929554-19|CAH72887.1|  699|Homo sapiens mannosidase, alpha, class
           1B, member 1 protein.
          Length = 699

 Score = 31.1 bits (67), Expect = 3.8
 Identities = 30/105 (28%), Positives = 48/105 (45%), Gaps = 1/105 (0%)
 Frame = +1

Query: 319 MFYHAYHAYMENAYPADELMPLSCK-GRWXGITPSRGDMDDALGNFXXXXXXXXXXXXXM 495
           +F HA+  Y + A+  DEL P+S     W G+  +  D  D +                +
Sbjct: 256 VFLHAWKGYRKFAWGHDELKPVSRSFSEWFGLGLTLIDALDTM--------------WIL 301

Query: 496 GDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLA 630
           G   +       + K     K + V++FE+ IR+LGGLLSA+ L+
Sbjct: 302 GLRKEFEEARKWVSKKLHFEKDVDVNLFESTIRILGGLLSAYHLS 346


>AL807752-35|CAI12781.1|  699|Homo sapiens mannosidase, alpha, class
           1B, member 1 protein.
          Length = 699

 Score = 31.1 bits (67), Expect = 3.8
 Identities = 30/105 (28%), Positives = 48/105 (45%), Gaps = 1/105 (0%)
 Frame = +1

Query: 319 MFYHAYHAYMENAYPADELMPLSCK-GRWXGITPSRGDMDDALGNFXXXXXXXXXXXXXM 495
           +F HA+  Y + A+  DEL P+S     W G+  +  D  D +                +
Sbjct: 256 VFLHAWKGYRKFAWGHDELKPVSRSFSEWFGLGLTLIDALDTM--------------WIL 301

Query: 496 GDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLA 630
           G   +       + K     K + V++FE+ IR+LGGLLSA+ L+
Sbjct: 302 GLRKEFEEARKWVSKKLHFEKDVDVNLFESTIRILGGLLSAYHLS 346


>AF148509-1|AAF03215.1|  699|Homo sapiens alpha 1,2-mannosidase
           protein.
          Length = 699

 Score = 31.1 bits (67), Expect = 3.8
 Identities = 30/105 (28%), Positives = 48/105 (45%), Gaps = 1/105 (0%)
 Frame = +1

Query: 319 MFYHAYHAYMENAYPADELMPLSCK-GRWXGITPSRGDMDDALGNFXXXXXXXXXXXXXM 495
           +F HA+  Y + A+  DEL P+S     W G+  +  D  D +                +
Sbjct: 256 VFLHAWKGYRKFAWGHDELKPVSRSFSEWFGLGLTLIDALDTM--------------WIL 301

Query: 496 GDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLA 630
           G   +       + K     K + V++FE+ IR+LGGLLSA+ L+
Sbjct: 302 GLRKEFEEARKWVSKKLHFEKDVDVNLFESTIRILGGLLSAYHLS 346


>AF145732-1|AAD45504.1|  663|Homo sapiens endoplasmic reticulum
           alpha-mannosidase I protein.
          Length = 663

 Score = 31.1 bits (67), Expect = 3.8
 Identities = 30/105 (28%), Positives = 48/105 (45%), Gaps = 1/105 (0%)
 Frame = +1

Query: 319 MFYHAYHAYMENAYPADELMPLSCK-GRWXGITPSRGDMDDALGNFXXXXXXXXXXXXXM 495
           +F HA+  Y + A+  DEL P+S     W G+  +  D  D +                +
Sbjct: 220 VFLHAWKGYRKFAWGHDELKPVSRSFSEWFGLGLTLIDALDTM--------------WIL 265

Query: 496 GDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLA 630
           G   +       + K     K + V++FE+ IR+LGGLLSA+ L+
Sbjct: 266 GLRKEFEEARKWVSKKLHFEKDVDVNLFESTIRILGGLLSAYHLS 310


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 98,647,025
Number of Sequences: 237096
Number of extensions: 2044973
Number of successful extensions: 2948
Number of sequences better than 10.0: 32
Number of HSP's better than 10.0 without gapping: 2848
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2938
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7839245960
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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