BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= NV060654.seq (687 letters) Database: human 237,096 sequences; 76,859,062 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AL096819-3|CAI21741.1| 932|Homo sapiens ER degradation enhancer... 115 1e-25 AF288393-1|AAG60613.1| 889|Homo sapiens C1orf22 protein. 115 1e-25 AL096819-2|CAI21740.1| 155|Homo sapiens ER degradation enhancer... 82 2e-15 AK023095-1|BAB14402.1| 155|Homo sapiens protein ( Homo sapiens ... 82 2e-15 BC105586-1|AAI05587.1| 242|Homo sapiens EDEM3 protein protein. 77 6e-14 D86967-1|BAA13203.2| 666|Homo sapiens KIAA0212 protein. 70 9e-12 BC019088-1|AAH19088.1| 657|Homo sapiens ER degradation enhancer... 70 9e-12 CR457266-1|CAG33547.1| 578|Homo sapiens C20orf31 protein. 67 5e-11 BC016184-1|AAH16184.1| 578|Homo sapiens ER degradation enhancer... 67 5e-11 BC001371-1|AAH01371.1| 578|Homo sapiens ER degradation enhancer... 67 5e-11 AL356652-1|CAH73763.1| 578|Homo sapiens ER degradation enhancer... 67 5e-11 AL135844-1|CAI19292.1| 578|Homo sapiens ER degradation enhancer... 67 5e-11 AK023931-1|BAB14731.1| 578|Homo sapiens protein ( Homo sapiens ... 67 5e-11 AK001645-1|BAA91806.1| 578|Homo sapiens protein ( Homo sapiens ... 67 5e-11 AY358580-1|AAQ88943.1| 541|Homo sapiens C20orf31 protein. 38 0.034 X74837-1|CAA52831.1| 625|Homo sapiens Man9-mannosidase protein. 36 0.18 AL078600-1|CAB75695.2| 653|Homo sapiens mannosidase, alpha, cla... 36 0.18 AL022722-2|CAI20315.1| 653|Homo sapiens mannosidase, alpha, cla... 36 0.18 BC065827-1|AAH65827.1| 367|Homo sapiens MAN1A1 protein protein. 35 0.24 BC063300-1|AAH63300.1| 641|Homo sapiens mannosidase, alpha, cla... 33 0.95 AL358072-1|CAH71079.1| 641|Homo sapiens mannosidase, alpha, cla... 33 0.95 AL157902-1|CAI22315.1| 641|Homo sapiens mannosidase, alpha, cla... 33 0.95 AF053621-1|AAC26200.1| 358|Homo sapiens alpha 1,2-mannosidase I... 33 0.95 AF027156-1|AAC26169.1| 641|Homo sapiens alpha 1,2-mannosidase I... 33 0.95 AK023308-1|BAB14518.1| 618|Homo sapiens protein ( Homo sapiens ... 33 1.3 BC006079-1|AAH06079.1| 699|Homo sapiens mannosidase, alpha, cla... 31 3.8 BC002953-1|AAH02953.1| 699|Homo sapiens mannosidase, alpha, cla... 31 3.8 AY358465-1|AAQ88830.1| 699|Homo sapiens MAN1B1 protein. 31 3.8 AL929554-19|CAH72887.1| 699|Homo sapiens mannosidase, alpha, cl... 31 3.8 AL807752-35|CAI12781.1| 699|Homo sapiens mannosidase, alpha, cl... 31 3.8 AF148509-1|AAF03215.1| 699|Homo sapiens alpha 1,2-mannosidase p... 31 3.8 AF145732-1|AAD45504.1| 663|Homo sapiens endoplasmic reticulum a... 31 3.8 >AL096819-3|CAI21741.1| 932|Homo sapiens ER degradation enhancer, mannosidase alpha-like 3 protein. Length = 932 Score = 115 bits (277), Expect = 1e-25 Identities = 62/133 (46%), Positives = 77/133 (57%) Frame = +1 Query: 274 MSKAERLSLRDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSRGDMDDALGNF 453 MS+ E+ L ++ +MF HAY YME+AYPADELMPL+C+GR G PSRGD+DDALG F Sbjct: 44 MSREEKQKLGNQVLEMFDHAYGNYMEHAYPADELMPLTCRGRVRGQEPSRGDVDDALGKF 103 Query: 454 XXXXXXXXXXXXXMGDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLAE 633 + + + + L +VVSVFETNIR+LGGLL H LA Sbjct: 104 SLTLIDSLDTLVVLNKTKEFEDAVRKVLRDVNLDNDVVVSVFETNIRVLGGLLGGHSLAI 163 Query: 634 TLKSDIPLXQWYN 672 LK QWYN Sbjct: 164 MLKEKGEYMQWYN 176 >AF288393-1|AAG60613.1| 889|Homo sapiens C1orf22 protein. Length = 889 Score = 115 bits (277), Expect = 1e-25 Identities = 62/133 (46%), Positives = 77/133 (57%) Frame = +1 Query: 274 MSKAERLSLRDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSRGDMDDALGNF 453 MS+ E+ L ++ +MF HAY YME+AYPADELMPL+C+GR G PSRGD+DDALG F Sbjct: 1 MSREEKQKLGNQVLEMFDHAYGNYMEHAYPADELMPLTCRGRVRGQEPSRGDVDDALGKF 60 Query: 454 XXXXXXXXXXXXXMGDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLAE 633 + + + + L +VVSVFETNIR+LGGLL H LA Sbjct: 61 SLTLIDSLDTLVVLNKTKEFEDAVRKVLRDVNLDNDVVVSVFETNIRVLGGLLGGHSLAI 120 Query: 634 TLKSDIPLXQWYN 672 LK QWYN Sbjct: 121 MLKEKGEYMQWYN 133 >AL096819-2|CAI21740.1| 155|Homo sapiens ER degradation enhancer, mannosidase alpha-like 3 protein. Length = 155 Score = 82.2 bits (194), Expect = 2e-15 Identities = 37/60 (61%), Positives = 46/60 (76%) Frame = +1 Query: 274 MSKAERLSLRDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSRGDMDDALGNF 453 MS+ E+ L ++ +MF HAY YME+AYPADELMPL+C+GR G PSRGD+DDALG F Sbjct: 44 MSREEKQKLGNQVLEMFDHAYGNYMEHAYPADELMPLTCRGRVRGQEPSRGDVDDALGKF 103 >AK023095-1|BAB14402.1| 155|Homo sapiens protein ( Homo sapiens cDNA FLJ13033 fis, clone NT2RP3001126. ). Length = 155 Score = 82.2 bits (194), Expect = 2e-15 Identities = 37/60 (61%), Positives = 46/60 (76%) Frame = +1 Query: 274 MSKAERLSLRDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSRGDMDDALGNF 453 MS+ E+ L ++ +MF HAY YME+AYPADELMPL+C+GR G PSRGD+DDALG F Sbjct: 44 MSREEKQKLGNQVLEMFDHAYGNYMEHAYPADELMPLTCRGRVRGQEPSRGDVDDALGKF 103 >BC105586-1|AAI05587.1| 242|Homo sapiens EDEM3 protein protein. Length = 242 Score = 77.0 bits (181), Expect = 6e-14 Identities = 43/99 (43%), Positives = 52/99 (52%) Frame = +1 Query: 376 MPLSCKGRWXGITPSRGDMDDALGNFXXXXXXXXXXXXXMGDFSDLIMQSNSL*KMSLLT 555 MPL+C+GR G PSRGD+DDALG F + + + + L Sbjct: 1 MPLTCRGRVRGQEPSRGDVDDALGKFSLTLIDSLDTLVVLNKTKEFEDAVRKVLRDVNLD 60 Query: 556 KILVVSVFETNIRMLGGLLSAHVLAETLKSDIPLXQWYN 672 +VVSVFETNIR+LGGLL H LA LK QWYN Sbjct: 61 NDVVVSVFETNIRVLGGLLGGHSLAIMLKEKGEYMQWYN 99 >D86967-1|BAA13203.2| 666|Homo sapiens KIAA0212 protein. Length = 666 Score = 69.7 bits (163), Expect = 9e-12 Identities = 41/112 (36%), Positives = 55/112 (49%), Gaps = 1/112 (0%) Frame = +1 Query: 289 RLSLRDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGI-TPSRGDMDDALGNFXXXX 465 R +RD +R MF Y YM +A+P DEL P+ C+GR PS +++D LGN+ Sbjct: 136 RAQMRDLARGMFVFGYDNYMAHAFPQDELNPIHCRGRGPDRGDPSNLNINDVLGNYSLTL 195 Query: 466 XXXXXXXXXMGDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAH 621 MG+ S+ + K V VFE IR+LG LLSAH Sbjct: 196 VDALDTLAIMGNSSEFQKAVKLVINTVSFDKDSTVQVFEATIRVLGSLLSAH 247 >BC019088-1|AAH19088.1| 657|Homo sapiens ER degradation enhancer, mannosidase alpha-like 1 protein. Length = 657 Score = 69.7 bits (163), Expect = 9e-12 Identities = 41/112 (36%), Positives = 55/112 (49%), Gaps = 1/112 (0%) Frame = +1 Query: 289 RLSLRDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGI-TPSRGDMDDALGNFXXXX 465 R +RD +R MF Y YM +A+P DEL P+ C+GR PS +++D LGN+ Sbjct: 127 RAQMRDLARGMFVFGYDNYMAHAFPQDELNPIHCRGRGPDRGDPSNLNINDVLGNYSLTL 186 Query: 466 XXXXXXXXXMGDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAH 621 MG+ S+ + K V VFE IR+LG LLSAH Sbjct: 187 VDALDTLAIMGNSSEFQKAVKLVINTVSFDKDSTVQVFEATIRVLGSLLSAH 238 >CR457266-1|CAG33547.1| 578|Homo sapiens C20orf31 protein. Length = 578 Score = 67.3 bits (157), Expect = 5e-11 Identities = 41/111 (36%), Positives = 57/111 (51%) Frame = +1 Query: 301 RDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSRGDMDDALGNFXXXXXXXXX 480 R+ + MFYHAY +Y+ENA+P DEL PL+C G D G+F Sbjct: 36 RERVKAMFYHAYDSYLENAFPFDELRPLTCDGH------------DTWGSFSLTLIDALD 83 Query: 481 XXXXMGDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLAE 633 +G+ S+ L + SVFETNIR++GGLLSAH+L++ Sbjct: 84 TLLILGNVSEFQRVVEVLQDSVDFDIDVNASVFETNIRVVGGLLSAHLLSK 134 >BC016184-1|AAH16184.1| 578|Homo sapiens ER degradation enhancer, mannosidase alpha-like 2 protein. Length = 578 Score = 67.3 bits (157), Expect = 5e-11 Identities = 41/111 (36%), Positives = 57/111 (51%) Frame = +1 Query: 301 RDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSRGDMDDALGNFXXXXXXXXX 480 R+ + MFYHAY +Y+ENA+P DEL PL+C G D G+F Sbjct: 36 RERVKAMFYHAYDSYLENAFPFDELRPLTCDGH------------DTWGSFSLTLIDALD 83 Query: 481 XXXXMGDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLAE 633 +G+ S+ L + SVFETNIR++GGLLSAH+L++ Sbjct: 84 TLLILGNVSEFQRVVEVLQDSVDFDIDVNASVFETNIRVVGGLLSAHLLSK 134 >BC001371-1|AAH01371.1| 578|Homo sapiens ER degradation enhancer, mannosidase alpha-like 2 protein. Length = 578 Score = 67.3 bits (157), Expect = 5e-11 Identities = 41/111 (36%), Positives = 57/111 (51%) Frame = +1 Query: 301 RDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSRGDMDDALGNFXXXXXXXXX 480 R+ + MFYHAY +Y+ENA+P DEL PL+C G D G+F Sbjct: 36 RERVKAMFYHAYDSYLENAFPFDELRPLTCDGH------------DTWGSFSLTLIDALD 83 Query: 481 XXXXMGDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLAE 633 +G+ S+ L + SVFETNIR++GGLLSAH+L++ Sbjct: 84 TLLILGNVSEFQRVVEVLQDSVDFDIDVNASVFETNIRVVGGLLSAHLLSK 134 >AL356652-1|CAH73763.1| 578|Homo sapiens ER degradation enhancer, mannosidase alpha-like 2 protein. Length = 578 Score = 67.3 bits (157), Expect = 5e-11 Identities = 41/111 (36%), Positives = 57/111 (51%) Frame = +1 Query: 301 RDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSRGDMDDALGNFXXXXXXXXX 480 R+ + MFYHAY +Y+ENA+P DEL PL+C G D G+F Sbjct: 36 RERVKAMFYHAYDSYLENAFPFDELRPLTCDGH------------DTWGSFSLTLIDALD 83 Query: 481 XXXXMGDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLAE 633 +G+ S+ L + SVFETNIR++GGLLSAH+L++ Sbjct: 84 TLLILGNVSEFQRVVEVLQDSVDFDIDVNASVFETNIRVVGGLLSAHLLSK 134 >AL135844-1|CAI19292.1| 578|Homo sapiens ER degradation enhancer, mannosidase alpha-like 2 protein. Length = 578 Score = 67.3 bits (157), Expect = 5e-11 Identities = 41/111 (36%), Positives = 57/111 (51%) Frame = +1 Query: 301 RDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSRGDMDDALGNFXXXXXXXXX 480 R+ + MFYHAY +Y+ENA+P DEL PL+C G D G+F Sbjct: 36 RERVKAMFYHAYDSYLENAFPFDELRPLTCDGH------------DTWGSFSLTLIDALD 83 Query: 481 XXXXMGDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLAE 633 +G+ S+ L + SVFETNIR++GGLLSAH+L++ Sbjct: 84 TLLILGNVSEFQRVVEVLQDSVDFDIDVNASVFETNIRVVGGLLSAHLLSK 134 >AK023931-1|BAB14731.1| 578|Homo sapiens protein ( Homo sapiens cDNA FLJ13869 fis, clone THYRO1001287, weakly similar to MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE (EC 3.2.1.113). ). Length = 578 Score = 67.3 bits (157), Expect = 5e-11 Identities = 41/111 (36%), Positives = 57/111 (51%) Frame = +1 Query: 301 RDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSRGDMDDALGNFXXXXXXXXX 480 R+ + MFYHAY +Y+ENA+P DEL PL+C G D G+F Sbjct: 36 RERVKAMFYHAYDSYLENAFPFDELRPLTCDGH------------DTWGSFSLTLIDALD 83 Query: 481 XXXXMGDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLAE 633 +G+ S+ L + SVFETNIR++GGLLSAH+L++ Sbjct: 84 TLLILGNVSEFQRVVEVLQDSVDFDIDVNASVFETNIRVVGGLLSAHLLSK 134 >AK001645-1|BAA91806.1| 578|Homo sapiens protein ( Homo sapiens cDNA FLJ10783 fis, clone NT2RP4000417, weakly similar to MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE (EC 3.2.1.113). ). Length = 578 Score = 67.3 bits (157), Expect = 5e-11 Identities = 41/111 (36%), Positives = 57/111 (51%) Frame = +1 Query: 301 RDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSRGDMDDALGNFXXXXXXXXX 480 R+ + MFYHAY +Y+ENA+P DEL PL+C G D G+F Sbjct: 36 RERVKAMFYHAYDSYLENAFPFDELRPLTCDGH------------DTWGSFSLTLIDALD 83 Query: 481 XXXXMGDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLAE 633 +G+ S+ L + SVFETNIR++GGLLSAH+L++ Sbjct: 84 TLLILGNVSEFQRVVEVLQDSVDFDIDVNASVFETNIRVVGGLLSAHLLSK 134 >AY358580-1|AAQ88943.1| 541|Homo sapiens C20orf31 protein. Length = 541 Score = 37.9 bits (84), Expect = 0.034 Identities = 16/21 (76%), Positives = 21/21 (100%) Frame = +1 Query: 571 SVFETNIRMLGGLLSAHVLAE 633 SVFETNIR++GGLLSAH+L++ Sbjct: 77 SVFETNIRVVGGLLSAHLLSK 97 >X74837-1|CAA52831.1| 625|Homo sapiens Man9-mannosidase protein. Length = 625 Score = 35.5 bits (78), Expect = 0.18 Identities = 31/111 (27%), Positives = 50/111 (45%), Gaps = 1/111 (0%) Frame = +1 Query: 301 RDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSRGDMDDALGNFXXXXXXXXX 480 R + ++M HA++ Y A+ +EL P+S KG G GN Sbjct: 168 RAKIKEMMKHAWNNYKGYAWGLNELKPIS-KG---------GHSSSLFGNIKGATIVDAL 217 Query: 481 XXXXMGDFSDLIMQSNSL*KMSLLTKILV-VSVFETNIRMLGGLLSAHVLA 630 + + ++ S + +L + +SVFE NIR +GGLLSA+ L+ Sbjct: 218 DTLFIMEMKHEFEEAKSWVEENLDFNVNAEISVFEVNIRFVGGLLSAYYLS 268 >AL078600-1|CAB75695.2| 653|Homo sapiens mannosidase, alpha, class 1A, member 1 protein. Length = 653 Score = 35.5 bits (78), Expect = 0.18 Identities = 31/111 (27%), Positives = 50/111 (45%), Gaps = 1/111 (0%) Frame = +1 Query: 301 RDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSRGDMDDALGNFXXXXXXXXX 480 R + ++M HA++ Y A+ +EL P+S KG G GN Sbjct: 196 RAKIKEMMKHAWNNYKGYAWGLNELKPIS-KG---------GHSSSLFGNIKGATIVDAL 245 Query: 481 XXXXMGDFSDLIMQSNSL*KMSLLTKILV-VSVFETNIRMLGGLLSAHVLA 630 + + ++ S + +L + +SVFE NIR +GGLLSA+ L+ Sbjct: 246 DTLFIMEMKHEFEEAKSWVEENLDFNVNAEISVFEVNIRFVGGLLSAYYLS 296 >AL022722-2|CAI20315.1| 653|Homo sapiens mannosidase, alpha, class 1A, member 1 protein. Length = 653 Score = 35.5 bits (78), Expect = 0.18 Identities = 31/111 (27%), Positives = 50/111 (45%), Gaps = 1/111 (0%) Frame = +1 Query: 301 RDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSRGDMDDALGNFXXXXXXXXX 480 R + ++M HA++ Y A+ +EL P+S KG G GN Sbjct: 196 RAKIKEMMKHAWNNYKGYAWGLNELKPIS-KG---------GHSSSLFGNIKGATIVDAL 245 Query: 481 XXXXMGDFSDLIMQSNSL*KMSLLTKILV-VSVFETNIRMLGGLLSAHVLA 630 + + ++ S + +L + +SVFE NIR +GGLLSA+ L+ Sbjct: 246 DTLFIMEMKHEFEEAKSWVEENLDFNVNAEISVFEVNIRFVGGLLSAYYLS 296 >BC065827-1|AAH65827.1| 367|Homo sapiens MAN1A1 protein protein. Length = 367 Score = 35.1 bits (77), Expect = 0.24 Identities = 31/106 (29%), Positives = 47/106 (44%), Gaps = 1/106 (0%) Frame = +1 Query: 316 QMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSRGDMDDALGNFXXXXXXXXXXXXXM 495 QM HA++ Y A+ +EL P+S KG G GN + Sbjct: 224 QMMKHAWNNYKGYAWGLNELKPIS-KG---------GHSSSLFGNIKGATIVDALDTLFI 273 Query: 496 GDFSDLIMQSNSL*KMSLLTKILV-VSVFETNIRMLGGLLSAHVLA 630 + ++ S + +L + +SVFE NIR +GGLLSA+ L+ Sbjct: 274 MEMKHEFEEAKSWVEENLDFNVNAEISVFEVNIRFVGGLLSAYYLS 319 >BC063300-1|AAH63300.1| 641|Homo sapiens mannosidase, alpha, class 1A, member 2 protein. Length = 641 Score = 33.1 bits (72), Expect = 0.95 Identities = 32/113 (28%), Positives = 47/113 (41%), Gaps = 3/113 (2%) Frame = +1 Query: 301 RDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSR---GDMDDALGNFXXXXXX 471 R++ ++M HA+ Y + +EL P++ KG I S + DAL Sbjct: 181 REKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLH 240 Query: 472 XXXXXXXMGDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLA 630 +L NS VSVFE NIR +GGLL+A+ L+ Sbjct: 241 DEFLDGQRWIEDNLDFSVNS-----------EVSVFEVNIRFIGGLLAAYYLS 282 >AL358072-1|CAH71079.1| 641|Homo sapiens mannosidase, alpha, class 1A, member 2 protein. Length = 641 Score = 33.1 bits (72), Expect = 0.95 Identities = 32/113 (28%), Positives = 47/113 (41%), Gaps = 3/113 (2%) Frame = +1 Query: 301 RDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSR---GDMDDALGNFXXXXXX 471 R++ ++M HA+ Y + +EL P++ KG I S + DAL Sbjct: 181 REKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLH 240 Query: 472 XXXXXXXMGDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLA 630 +L NS VSVFE NIR +GGLL+A+ L+ Sbjct: 241 DEFLDGQRWIEDNLDFSVNS-----------EVSVFEVNIRFIGGLLAAYYLS 282 >AL157902-1|CAI22315.1| 641|Homo sapiens mannosidase, alpha, class 1A, member 2 protein. Length = 641 Score = 33.1 bits (72), Expect = 0.95 Identities = 32/113 (28%), Positives = 47/113 (41%), Gaps = 3/113 (2%) Frame = +1 Query: 301 RDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSR---GDMDDALGNFXXXXXX 471 R++ ++M HA+ Y + +EL P++ KG I S + DAL Sbjct: 181 REKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLH 240 Query: 472 XXXXXXXMGDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLA 630 +L NS VSVFE NIR +GGLL+A+ L+ Sbjct: 241 DEFLDGQRWIEDNLDFSVNS-----------EVSVFEVNIRFIGGLLAAYYLS 282 >AF053621-1|AAC26200.1| 358|Homo sapiens alpha 1,2-mannosidase IB protein. Length = 358 Score = 33.1 bits (72), Expect = 0.95 Identities = 32/113 (28%), Positives = 47/113 (41%), Gaps = 3/113 (2%) Frame = +1 Query: 301 RDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSR---GDMDDALGNFXXXXXX 471 R++ ++M HA+ Y + +EL P++ KG I S + DAL Sbjct: 181 REKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLH 240 Query: 472 XXXXXXXMGDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLA 630 +L NS VSVFE NIR +GGLL+A+ L+ Sbjct: 241 DEFLDGQRWIEDNLDFSVNS-----------EVSVFEVNIRFIGGLLAAYYLS 282 >AF027156-1|AAC26169.1| 641|Homo sapiens alpha 1,2-mannosidase IB protein. Length = 641 Score = 33.1 bits (72), Expect = 0.95 Identities = 32/113 (28%), Positives = 47/113 (41%), Gaps = 3/113 (2%) Frame = +1 Query: 301 RDESRQMFYHAYHAYMENAYPADELMPLSCKGRWXGITPSR---GDMDDALGNFXXXXXX 471 R++ ++M HA+ Y + +EL P++ KG I S + DAL Sbjct: 181 REKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLH 240 Query: 472 XXXXXXXMGDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLA 630 +L NS VSVFE NIR +GGLL+A+ L+ Sbjct: 241 DEFLDGQRWIEDNLDFSVNS-----------EVSVFEVNIRFIGGLLAAYYLS 282 >AK023308-1|BAB14518.1| 618|Homo sapiens protein ( Homo sapiens cDNA FLJ13246 fis, clone OVARC1000682, highly similar to PROCESSING ALPHA-1,2-MANNOSIDASE (EC 3.2.1.-). ). Length = 618 Score = 32.7 bits (71), Expect = 1.3 Identities = 14/21 (66%), Positives = 18/21 (85%) Frame = +1 Query: 568 VSVFETNIRMLGGLLSAHVLA 630 VSVFE NIR +GGLL+A+ L+ Sbjct: 52 VSVFEVNIRFIGGLLAAYYLS 72 >BC006079-1|AAH06079.1| 699|Homo sapiens mannosidase, alpha, class 1B, member 1 protein. Length = 699 Score = 31.1 bits (67), Expect = 3.8 Identities = 30/105 (28%), Positives = 48/105 (45%), Gaps = 1/105 (0%) Frame = +1 Query: 319 MFYHAYHAYMENAYPADELMPLSCK-GRWXGITPSRGDMDDALGNFXXXXXXXXXXXXXM 495 +F HA+ Y + A+ DEL P+S W G+ + D D + + Sbjct: 256 VFLHAWKGYRKFAWGHDELKPVSRSFSEWFGLGLTLIDALDTM--------------WIL 301 Query: 496 GDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLA 630 G + + K K + V++FE+ IR+LGGLLSA+ L+ Sbjct: 302 GLRKEFEEARKWVSKKLHFEKDVDVNLFESTIRILGGLLSAYHLS 346 >BC002953-1|AAH02953.1| 699|Homo sapiens mannosidase, alpha, class 1B, member 1 protein. Length = 699 Score = 31.1 bits (67), Expect = 3.8 Identities = 30/105 (28%), Positives = 48/105 (45%), Gaps = 1/105 (0%) Frame = +1 Query: 319 MFYHAYHAYMENAYPADELMPLSCK-GRWXGITPSRGDMDDALGNFXXXXXXXXXXXXXM 495 +F HA+ Y + A+ DEL P+S W G+ + D D + + Sbjct: 256 VFLHAWKGYRKFAWGHDELKPVSRSFSEWFGLGLTLIDALDTM--------------WIL 301 Query: 496 GDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLA 630 G + + K K + V++FE+ IR+LGGLLSA+ L+ Sbjct: 302 GLRKEFEEARKWVSKKLHFEKDVDVNLFESTIRILGGLLSAYHLS 346 >AY358465-1|AAQ88830.1| 699|Homo sapiens MAN1B1 protein. Length = 699 Score = 31.1 bits (67), Expect = 3.8 Identities = 30/105 (28%), Positives = 48/105 (45%), Gaps = 1/105 (0%) Frame = +1 Query: 319 MFYHAYHAYMENAYPADELMPLSCK-GRWXGITPSRGDMDDALGNFXXXXXXXXXXXXXM 495 +F HA+ Y + A+ DEL P+S W G+ + D D + + Sbjct: 256 VFLHAWKGYRKFAWGHDELKPVSRSFSEWFGLGLTLIDALDTM--------------WIL 301 Query: 496 GDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLA 630 G + + K K + V++FE+ IR+LGGLLSA+ L+ Sbjct: 302 GLRKEFEEARKWVSKKLHFEKDVDVNLFESTIRILGGLLSAYHLS 346 >AL929554-19|CAH72887.1| 699|Homo sapiens mannosidase, alpha, class 1B, member 1 protein. Length = 699 Score = 31.1 bits (67), Expect = 3.8 Identities = 30/105 (28%), Positives = 48/105 (45%), Gaps = 1/105 (0%) Frame = +1 Query: 319 MFYHAYHAYMENAYPADELMPLSCK-GRWXGITPSRGDMDDALGNFXXXXXXXXXXXXXM 495 +F HA+ Y + A+ DEL P+S W G+ + D D + + Sbjct: 256 VFLHAWKGYRKFAWGHDELKPVSRSFSEWFGLGLTLIDALDTM--------------WIL 301 Query: 496 GDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLA 630 G + + K K + V++FE+ IR+LGGLLSA+ L+ Sbjct: 302 GLRKEFEEARKWVSKKLHFEKDVDVNLFESTIRILGGLLSAYHLS 346 >AL807752-35|CAI12781.1| 699|Homo sapiens mannosidase, alpha, class 1B, member 1 protein. Length = 699 Score = 31.1 bits (67), Expect = 3.8 Identities = 30/105 (28%), Positives = 48/105 (45%), Gaps = 1/105 (0%) Frame = +1 Query: 319 MFYHAYHAYMENAYPADELMPLSCK-GRWXGITPSRGDMDDALGNFXXXXXXXXXXXXXM 495 +F HA+ Y + A+ DEL P+S W G+ + D D + + Sbjct: 256 VFLHAWKGYRKFAWGHDELKPVSRSFSEWFGLGLTLIDALDTM--------------WIL 301 Query: 496 GDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLA 630 G + + K K + V++FE+ IR+LGGLLSA+ L+ Sbjct: 302 GLRKEFEEARKWVSKKLHFEKDVDVNLFESTIRILGGLLSAYHLS 346 >AF148509-1|AAF03215.1| 699|Homo sapiens alpha 1,2-mannosidase protein. Length = 699 Score = 31.1 bits (67), Expect = 3.8 Identities = 30/105 (28%), Positives = 48/105 (45%), Gaps = 1/105 (0%) Frame = +1 Query: 319 MFYHAYHAYMENAYPADELMPLSCK-GRWXGITPSRGDMDDALGNFXXXXXXXXXXXXXM 495 +F HA+ Y + A+ DEL P+S W G+ + D D + + Sbjct: 256 VFLHAWKGYRKFAWGHDELKPVSRSFSEWFGLGLTLIDALDTM--------------WIL 301 Query: 496 GDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLA 630 G + + K K + V++FE+ IR+LGGLLSA+ L+ Sbjct: 302 GLRKEFEEARKWVSKKLHFEKDVDVNLFESTIRILGGLLSAYHLS 346 >AF145732-1|AAD45504.1| 663|Homo sapiens endoplasmic reticulum alpha-mannosidase I protein. Length = 663 Score = 31.1 bits (67), Expect = 3.8 Identities = 30/105 (28%), Positives = 48/105 (45%), Gaps = 1/105 (0%) Frame = +1 Query: 319 MFYHAYHAYMENAYPADELMPLSCK-GRWXGITPSRGDMDDALGNFXXXXXXXXXXXXXM 495 +F HA+ Y + A+ DEL P+S W G+ + D D + + Sbjct: 220 VFLHAWKGYRKFAWGHDELKPVSRSFSEWFGLGLTLIDALDTM--------------WIL 265 Query: 496 GDFSDLIMQSNSL*KMSLLTKILVVSVFETNIRMLGGLLSAHVLA 630 G + + K K + V++FE+ IR+LGGLLSA+ L+ Sbjct: 266 GLRKEFEEARKWVSKKLHFEKDVDVNLFESTIRILGGLLSAYHLS 310 Database: human Posted date: Oct 23, 2007 1:18 PM Number of letters in database: 76,859,062 Number of sequences in database: 237,096 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 98,647,025 Number of Sequences: 237096 Number of extensions: 2044973 Number of successful extensions: 2948 Number of sequences better than 10.0: 32 Number of HSP's better than 10.0 without gapping: 2848 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2938 length of database: 76,859,062 effective HSP length: 88 effective length of database: 55,994,614 effective search space used: 7839245960 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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