Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= NV060631.seq
(541 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000D563F8 Cluster: PREDICTED: similar to CG9165-PA;... 113 3e-24
UniRef50_UPI0000DB6D6A Cluster: PREDICTED: similar to Porphobili... 112 6e-24
UniRef50_Q9W0G4 Cluster: CG9165-PA; n=6; Coelomata|Rep: CG9165-P... 108 9e-23
UniRef50_Q0IEI9 Cluster: Porphobilinogen deaminase; n=4; Coeloma... 106 3e-22
UniRef50_P08397 Cluster: Porphobilinogen deaminase; n=50; Eutele... 100 4e-20
UniRef50_UPI0000583C22 Cluster: PREDICTED: hypothetical protein;... 99 6e-20
UniRef50_Q4T5L1 Cluster: Chromosome undetermined SCAF9206, whole... 98 1e-19
UniRef50_Q86ET2 Cluster: Clone ZZD1450 mRNA sequence; n=2; Schis... 92 9e-18
UniRef50_Q8YVU6 Cluster: Porphobilinogen deaminase; n=42; Bacter... 92 9e-18
UniRef50_Q2RJ26 Cluster: Porphobilinogen deaminase; n=2; Clostri... 87 2e-16
UniRef50_Q54P93 Cluster: Porphobilinogen deaminase; n=1; Dictyos... 86 6e-16
UniRef50_P28789 Cluster: Porphobilinogen deaminase; n=9; Ascomyc... 82 7e-15
UniRef50_P16616 Cluster: Porphobilinogen deaminase; n=22; Bacill... 82 9e-15
UniRef50_Q3E1E4 Cluster: Porphobilinogen deaminase; n=3; Chlorof... 80 4e-14
UniRef50_Q5KWK6 Cluster: Porphobilinogen deaminase; n=32; Bacill... 79 6e-14
UniRef50_Q7U5C2 Cluster: Porphobilinogen deaminase; n=24; Bacter... 79 9e-14
UniRef50_Q92HR5 Cluster: Porphobilinogen deaminase; n=9; Rickett... 79 9e-14
UniRef50_Q6C097 Cluster: Porphobilinogen deaminase; n=10; Ascomy... 78 1e-13
UniRef50_Q9RRY0 Cluster: Porphobilinogen deaminase; n=4; Deinoco... 78 1e-13
UniRef50_O66621 Cluster: Porphobilinogen deaminase; n=2; Aquifex... 78 1e-13
UniRef50_Q1Q7D2 Cluster: Strongly similar to hydroxymethylbilane... 77 3e-13
UniRef50_Q0EVH8 Cluster: Porphobilinogen deaminase; n=2; Thermoa... 77 3e-13
UniRef50_Q8XWW3 Cluster: Porphobilinogen deaminase; n=71; Proteo... 77 3e-13
UniRef50_Q2LQU2 Cluster: Porphobilinogen deaminase; n=1; Syntrop... 76 5e-13
UniRef50_Q8KCJ4 Cluster: Porphobilinogen deaminase; n=11; Chloro... 76 5e-13
UniRef50_Q1QEM1 Cluster: Porphobilinogen deaminase; n=2; Psychro... 76 6e-13
UniRef50_A1WVT9 Cluster: Porphobilinogen deaminase; n=5; Gammapr... 75 1e-12
UniRef50_A3CL78 Cluster: Porphobilinogen deaminase, putative; n=... 75 1e-12
UniRef50_Q9KVM1 Cluster: Porphobilinogen deaminase; n=57; Gammap... 75 1e-12
UniRef50_Q602K3 Cluster: Porphobilinogen deaminase; n=26; cellul... 74 2e-12
UniRef50_Q75DY0 Cluster: Porphobilinogen deaminase; n=7; Ascomyc... 74 2e-12
UniRef50_Q5ZRY6 Cluster: Porphobilinogen deaminase; n=5; Legione... 73 4e-12
UniRef50_Q180R9 Cluster: Porphobilinogen deaminase; n=3; Clostri... 72 7e-12
UniRef50_Q0EWI8 Cluster: Porphobilinogen deaminase; n=2; Proteob... 72 7e-12
UniRef50_Q92LH7 Cluster: Porphobilinogen deaminase; n=53; cellul... 72 7e-12
UniRef50_Q5WEP5 Cluster: Porphobilinogen deaminase; n=2; Firmicu... 72 7e-12
UniRef50_Q1EPC8 Cluster: Porphobilinogen deaminase, chloroplast ... 71 1e-11
UniRef50_A0RXB2 Cluster: Porphobilinogen deaminase; n=2; Thermop... 71 2e-11
UniRef50_Q0GL46 Cluster: Porphobilinogen deaminase; n=3; Lactoba... 71 2e-11
UniRef50_A6GB01 Cluster: Porphobilinogen deaminase; n=1; Plesioc... 71 2e-11
UniRef50_A5ZY88 Cluster: Putative uncharacterized protein; n=3; ... 71 2e-11
UniRef50_Q09899 Cluster: Porphobilinogen deaminase; n=1; Schizos... 70 3e-11
UniRef50_P46355 Cluster: Porphobilinogen deaminase; n=144; Bacte... 69 5e-11
UniRef50_O94048 Cluster: Porphobilinogen deaminase; n=4; Ascomyc... 69 5e-11
UniRef50_A6Q7Y4 Cluster: Porphobilinogen deaminase; n=1; Sulfuro... 69 7e-11
UniRef50_A6LKX0 Cluster: Porphobilinogen deaminase; n=1; Thermos... 69 9e-11
UniRef50_Q6BM23 Cluster: Porphobilinogen deaminase; n=6; Sacchar... 67 2e-10
UniRef50_Q57B08 Cluster: Porphobilinogen deaminase; n=7; Rhizobi... 67 2e-10
UniRef50_Q2S2A6 Cluster: Porphobilinogen deaminase; n=1; Salinib... 67 3e-10
UniRef50_Q59293 Cluster: Porphobilinogen deaminase; n=5; Clostri... 66 4e-10
UniRef50_Q7M8L2 Cluster: Porphobilinogen deaminase; n=6; Bacteri... 66 6e-10
UniRef50_Q97MU4 Cluster: Porphobilinogen deaminase; n=12; Clostr... 66 6e-10
UniRef50_Q43316 Cluster: Porphobilinogen deaminase, chloroplast ... 66 6e-10
UniRef50_Q0ATQ1 Cluster: Porphobilinogen deaminase; n=3; Alphapr... 65 1e-09
UniRef50_A6EES9 Cluster: Porphobilinogen deaminase; n=1; Pedobac... 65 1e-09
UniRef50_O26960 Cluster: Probable porphobilinogen deaminase; n=2... 65 1e-09
UniRef50_Q5FPS5 Cluster: Porphobilinogen deaminase; n=3; Acetoba... 64 3e-09
UniRef50_Q57989 Cluster: Probable porphobilinogen deaminase; n=6... 64 3e-09
UniRef50_Q8ZYW7 Cluster: Probable porphobilinogen deaminase; n=3... 63 3e-09
UniRef50_A5KJC5 Cluster: Putative uncharacterized protein; n=1; ... 63 5e-09
UniRef50_A2BL26 Cluster: Probable porphobilinogen deaminase; n=2... 63 5e-09
UniRef50_Q1XAN5 Cluster: Putative porphobilinogen deaminase; n=2... 62 6e-09
UniRef50_A4CHM3 Cluster: Porphobilinogen deaminase; n=3; Flavoba... 62 6e-09
UniRef50_Q7RNI8 Cluster: Porphobilinogen deaminase, putative; n=... 62 8e-09
UniRef50_Q9ABZ8 Cluster: Porphobilinogen deaminase; n=2; Cauloba... 62 8e-09
UniRef50_A6C1S2 Cluster: Porphobilinogen deaminase; n=1; Plancto... 61 1e-08
UniRef50_Q7VFE9 Cluster: Porphobilinogen deaminase; n=19; Epsilo... 61 2e-08
UniRef50_Q0UDH2 Cluster: Putative uncharacterized protein; n=1; ... 60 3e-08
UniRef50_Q8TT56 Cluster: Probable porphobilinogen deaminase; n=6... 60 4e-08
UniRef50_Q8RFP5 Cluster: Porphobilinogen deaminase; n=3; Fusobac... 60 4e-08
UniRef50_A5CDH4 Cluster: Porphobilinogen deaminase; n=1; Orienti... 59 6e-08
UniRef50_Q8EY46 Cluster: Porphobilinogen deaminase; n=4; Leptosp... 59 7e-08
UniRef50_Q8TXC8 Cluster: Probable porphobilinogen deaminase; n=2... 58 1e-07
UniRef50_Q1AUK3 Cluster: Porphobilinogen deaminase; n=1; Rubroba... 58 1e-07
UniRef50_Q0BX92 Cluster: Porphobilinogen deaminase; n=1; Hyphomo... 58 1e-07
UniRef50_A4BYX0 Cluster: Porphobilinogen deaminase HemC; n=11; B... 58 2e-07
UniRef50_Q2NEP4 Cluster: HemC; n=1; Methanosphaera stadtmanae DS... 58 2e-07
UniRef50_Q4PFH9 Cluster: Putative uncharacterized protein; n=1; ... 57 2e-07
UniRef50_Q9HMY5 Cluster: Probable porphobilinogen deaminase; n=1... 57 2e-07
UniRef50_Q11XT5 Cluster: Porphobilinogen deaminase; n=6; Bacteri... 57 2e-07
UniRef50_Q3W4S6 Cluster: Porphobilinogen deaminase; n=1; Frankia... 56 4e-07
UniRef50_Q83A37 Cluster: Porphobilinogen deaminase; n=3; Coxiell... 56 4e-07
UniRef50_UPI0000DAE5D1 Cluster: hypothetical protein Rgryl_01000... 56 5e-07
UniRef50_A3H5P0 Cluster: Porphobilinogen deaminase; n=1; Caldivi... 56 5e-07
UniRef50_Q9F7M2 Cluster: Predicted porphobilinogen deaminase; n=... 56 7e-07
UniRef50_Q2JFS0 Cluster: Porphobilinogen deaminase; n=2; Frankia... 55 9e-07
UniRef50_Q2GJX6 Cluster: Porphobilinogen deaminase; n=11; Ricket... 55 9e-07
UniRef50_O29026 Cluster: Probable porphobilinogen deaminase; n=1... 55 9e-07
UniRef50_A5K0J5 Cluster: Porphobilinogen deaminase, putative; n=... 54 2e-06
UniRef50_UPI00006CBE06 Cluster: porphobilinogen deaminase family... 53 5e-06
UniRef50_Q6MHU0 Cluster: Hydroxymethylbilane synthase; n=1; Bdel... 53 5e-06
UniRef50_A1DGB8 Cluster: Porphobilinogen deaminase; n=1; Neosart... 53 5e-06
UniRef50_Q2FTK7 Cluster: Porphobilinogen deaminase; n=1; Methano... 53 5e-06
UniRef50_Q6MEK3 Cluster: Putative Porphobilinogen deaminase; n=1... 52 6e-06
UniRef50_Q5HBG1 Cluster: Porphobilinogen deaminase; n=2; Ehrlich... 52 6e-06
UniRef50_Q1GP41 Cluster: Porphobilinogen deaminase; n=7; Sphingo... 52 8e-06
UniRef50_A3ZKX4 Cluster: Porphobilinogen deaminase; n=1; Blastop... 52 8e-06
UniRef50_Q5NL83 Cluster: Porphobilinogen deaminase; n=1; Zymomon... 52 1e-05
UniRef50_Q6L2G8 Cluster: Probable porphobilinogen deaminase; n=2... 52 1e-05
UniRef50_Q2GE22 Cluster: Putative porphobilinogen deaminase; n=1... 51 1e-05
UniRef50_Q93A65 Cluster: Porphobilinogen deaminase; n=1; uncultu... 51 1e-05
UniRef50_Q5KKQ0 Cluster: Hydroxymethylbilane synthase, putative;... 51 1e-05
UniRef50_Q5UY52 Cluster: Porphobilinogen deaminase; n=3; Halobac... 50 3e-05
UniRef50_A2Q9P7 Cluster: Catalytic activity: 4 porphobilinogen+H... 50 5e-05
UniRef50_UPI00015BAF19 Cluster: hydroxymethylbilane synthase; n=... 49 6e-05
UniRef50_A0DD68 Cluster: Chromosome undetermined scaffold_46, wh... 49 8e-05
UniRef50_Q4FNV7 Cluster: Hydroxymethylbilane synthase; n=2; Cand... 48 1e-04
UniRef50_A7D1I3 Cluster: Porphobilinogen deaminase; n=1; Halorub... 47 3e-04
UniRef50_Q9Y9J0 Cluster: Probable porphobilinogen deaminase; n=1... 46 7e-04
UniRef50_Q7UPN0 Cluster: Porphobilinogen deaminase; n=1; Pirellu... 45 0.001
UniRef50_A0LRF1 Cluster: Porphobilinogen deaminase precursor; n=... 44 0.002
UniRef50_Q97B26 Cluster: Probable porphobilinogen deaminase; n=2... 44 0.002
UniRef50_UPI000155526F Cluster: PREDICTED: similar to hydroxymet... 44 0.003
UniRef50_Q6AB05 Cluster: Porphobilinogen deaminase; n=17; Actino... 44 0.003
UniRef50_A5CNI4 Cluster: HemC protein; n=2; Actinobacteria (clas... 43 0.004
UniRef50_A4YD92 Cluster: Porphobilinogen deaminase; n=1; Metallo... 43 0.005
UniRef50_Q82P95 Cluster: Porphobilinogen deaminase 2; n=3; Strep... 42 0.009
UniRef50_Q8NT90 Cluster: Porphobilinogen deaminase; n=5; Coryneb... 42 0.012
UniRef50_Q8D2W2 Cluster: HemC protein; n=1; Wigglesworthia gloss... 41 0.016
UniRef50_A4XK06 Cluster: Porphobilinogen deaminase; n=1; Caldice... 41 0.016
UniRef50_Q5YP70 Cluster: Porphobilinogen deaminase; n=18; Actino... 40 0.048
UniRef50_Q976H1 Cluster: Probable porphobilinogen deaminase; n=3... 39 0.064
UniRef50_Q9PK95 Cluster: Probable porphobilinogen deaminase; n=7... 38 0.20
UniRef50_A6R1N6 Cluster: Predicted protein; n=1; Ajellomyces cap... 35 1.0
UniRef50_A4YPB9 Cluster: Porphobilinogen deaminase; n=8; Bradyrh... 35 1.4
UniRef50_A6EWA1 Cluster: Putative uncharacterized protein; n=1; ... 32 7.3
UniRef50_UPI0000D9FBB5 Cluster: PREDICTED: similar to lethal (3)... 32 9.7
>UniRef50_UPI0000D563F8 Cluster: PREDICTED: similar to CG9165-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG9165-PA - Tribolium castaneum
Length = 460
Score = 113 bits (271), Expect = 3e-24
Identities = 56/88 (63%), Positives = 68/88 (77%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
++ +AL+QT VI LK+ +P K+F+IVTM+TLGD+VLD PLP IGEKSL TK L AL
Sbjct: 12 RKSELALIQTRHVISLLKKIHPGKDFEIVTMSTLGDKVLDIPLPKIGEKSLFTKELEAAL 71
Query: 422 MSKNVDFVVHSLKDLPTTLPDGLVIGAV 505
+ VDFVVHSLKDLPT LP G+ IGAV
Sbjct: 72 STGCVDFVVHSLKDLPTVLPPGMAIGAV 99
>UniRef50_UPI0000DB6D6A Cluster: PREDICTED: similar to
Porphobilinogen deaminase (Hydroxymethylbilane synthase)
(HMBS) (Pre-uroporphyrinogen synthase) (PBG-D); n=1;
Apis mellifera|Rep: PREDICTED: similar to
Porphobilinogen deaminase (Hydroxymethylbilane synthase)
(HMBS) (Pre-uroporphyrinogen synthase) (PBG-D) - Apis
mellifera
Length = 357
Score = 112 bits (269), Expect = 6e-24
Identities = 52/90 (57%), Positives = 70/90 (77%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
++ +AL QT +VI+ LK +P KEF+I+TM+T GD++LD+ LP IGEKSL T+ L AL
Sbjct: 15 RKSELALKQTKYVIECLKEYHPTKEFQIITMSTKGDKILDKSLPKIGEKSLFTEELELAL 74
Query: 422 MSKNVDFVVHSLKDLPTTLPDGLVIGAVFK 511
S VDFVVHSLKDLPT+LP+G+ +GA+ K
Sbjct: 75 ESGRVDFVVHSLKDLPTSLPEGMALGAILK 104
>UniRef50_Q9W0G4 Cluster: CG9165-PA; n=6; Coelomata|Rep: CG9165-PA -
Drosophila melanogaster (Fruit fly)
Length = 652
Score = 108 bits (259), Expect = 9e-23
Identities = 52/90 (57%), Positives = 68/90 (75%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
++ +AL+QT VI L++ YP+++F+I TM+T GDRVL+ LP IGEKSL T+ L DAL
Sbjct: 13 RKSELALIQTKHVIGRLQKLYPKQKFEIHTMSTFGDRVLNVSLPKIGEKSLFTRDLEDAL 72
Query: 422 MSKNVDFVVHSLKDLPTTLPDGLVIGAVFK 511
+ VDFVVHSLKDLPT LP G+ IGAV +
Sbjct: 73 RNGGVDFVVHSLKDLPTALPTGMAIGAVLE 102
>UniRef50_Q0IEI9 Cluster: Porphobilinogen deaminase; n=4;
Coelomata|Rep: Porphobilinogen deaminase - Aedes aegypti
(Yellowfever mosquito)
Length = 534
Score = 106 bits (255), Expect = 3e-22
Identities = 52/90 (57%), Positives = 69/90 (76%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
++ +AL+QT VI L++ P+ +++I TMTT+GDRVL++ LP IGEKSL TK L DAL
Sbjct: 15 RKSELALIQTKHVIACLQKLNPDVQYEIHTMTTVGDRVLNKSLPKIGEKSLFTKDLEDAL 74
Query: 422 MSKNVDFVVHSLKDLPTTLPDGLVIGAVFK 511
+ VDFVVHSLKDLPT+LP G+ IGAV +
Sbjct: 75 RNGGVDFVVHSLKDLPTSLPIGMAIGAVLE 104
>UniRef50_P08397 Cluster: Porphobilinogen deaminase; n=50;
Euteleostomi|Rep: Porphobilinogen deaminase - Homo
sapiens (Human)
Length = 361
Score = 99.5 bits (237), Expect = 4e-20
Identities = 47/90 (52%), Positives = 63/90 (70%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
++ ++A +QT+ V+ +LK +YP +F+I+ M+T GD++LD L IGEKSL TK L AL
Sbjct: 26 RKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHAL 85
Query: 422 MSKNVDFVVHSLKDLPTTLPDGLVIGAVFK 511
VD VVHSLKDLPT LP G IGA+ K
Sbjct: 86 EKNEVDLVVHSLKDLPTVLPPGFTIGAICK 115
>UniRef50_UPI0000583C22 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 324
Score = 99.1 bits (236), Expect = 6e-20
Identities = 44/88 (50%), Positives = 63/88 (71%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
++ +A++QTN V++ L++ +PE EFKIVTM T+GD + D+PL IGE +L TK L AL
Sbjct: 13 RKSELAMIQTNHVVEMLQKVHPETEFKIVTMETIGDHIQDKPLASIGESNLFTKELEKAL 72
Query: 422 MSKNVDFVVHSLKDLPTTLPDGLVIGAV 505
VD +VHSLKD+P+ LP + IGA+
Sbjct: 73 ALDEVDMLVHSLKDMPSRLPSNMAIGAI 100
>UniRef50_Q4T5L1 Cluster: Chromosome undetermined SCAF9206, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF9206, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 385
Score = 97.9 bits (233), Expect = 1e-19
Identities = 48/87 (55%), Positives = 60/87 (68%)
Frame = +2
Query: 251 RVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSK 430
++A +QT+ V + LK YP+ +IV M+T GD++LD L IGEKSL TK L +AL
Sbjct: 2 QLARIQTDSVAEKLKELYPDVHLEIVAMSTTGDKILDTALSKIGEKSLFTKELENALERN 61
Query: 431 NVDFVVHSLKDLPTTLPDGLVIGAVFK 511
VD VVHSLKDLPT+LP G IGAV K
Sbjct: 62 EVDLVVHSLKDLPTSLPPGFTIGAVLK 88
>UniRef50_Q86ET2 Cluster: Clone ZZD1450 mRNA sequence; n=2;
Schistosoma japonicum|Rep: Clone ZZD1450 mRNA sequence -
Schistosoma japonicum (Blood fluke)
Length = 277
Score = 91.9 bits (218), Expect = 9e-18
Identities = 47/98 (47%), Positives = 64/98 (65%), Gaps = 2/98 (2%)
Frame = +2
Query: 221 TKHSRRLQEER--VALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSL 394
++H+ R+ R +AL+QT I LK P F++V + T+GD +LD PL IG+KSL
Sbjct: 6 SQHAVRVGSRRSNLALLQTEMAISLLKVQKPHIMFEVVEIATVGDEILDVPLSKIGDKSL 65
Query: 395 XTKXLXDALMSKNVDFVVHSLKDLPTTLPDGLVIGAVF 508
TK L +L+ VD VVHSLKD+P+ LP GLV+G VF
Sbjct: 66 FTKELEKSLLVGEVDLVVHSLKDVPSVLPTGLVLGCVF 103
>UniRef50_Q8YVU6 Cluster: Porphobilinogen deaminase; n=42;
Bacteria|Rep: Porphobilinogen deaminase - Anabaena sp.
(strain PCC 7120)
Length = 323
Score = 91.9 bits (218), Expect = 9e-18
Identities = 40/88 (45%), Positives = 64/88 (72%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
++ ++ALVQT +V + L+ ++P+ F++ TM+T GD++LD L IG+K L TK L +
Sbjct: 17 RKSQLALVQTYWVREQLQNSFPDINFEVHTMSTQGDKILDVALAKIGDKGLFTKELEVGM 76
Query: 422 MSKNVDFVVHSLKDLPTTLPDGLVIGAV 505
+++ +DF VHSLKDLPT LP+GL + A+
Sbjct: 77 INEEIDFAVHSLKDLPTNLPEGLALAAI 104
>UniRef50_Q2RJ26 Cluster: Porphobilinogen deaminase; n=2;
Clostridia|Rep: Porphobilinogen deaminase - Moorella
thermoacetica (strain ATCC 39073)
Length = 313
Score = 87.4 bits (207), Expect = 2e-16
Identities = 41/88 (46%), Positives = 60/88 (68%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
+E +A Q +VI +L++ +P ++VT+ T GD++LD L IG+K L TK L AL
Sbjct: 9 RESELARWQARWVIQALEKAWPGLSCRLVTLKTKGDKILDVALARIGDKGLFTKELELAL 68
Query: 422 MSKNVDFVVHSLKDLPTTLPDGLVIGAV 505
+ +D VHS+KD+PTTLP+GLVIGA+
Sbjct: 69 LDGAIDLAVHSMKDMPTTLPEGLVIGAI 96
>UniRef50_Q54P93 Cluster: Porphobilinogen deaminase; n=1;
Dictyostelium discoideum AX4|Rep: Porphobilinogen
deaminase - Dictyostelium discoideum AX4
Length = 325
Score = 85.8 bits (203), Expect = 6e-16
Identities = 41/90 (45%), Positives = 60/90 (66%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
++ ++A++QT +V D ++ P +I TM T GD+VLD L IG+K L TK L D +
Sbjct: 15 RKSQLAMLQTEWVRDRIQELNPGIIVEIKTMDTTGDKVLDVSLSKIGDKGLFTKELEDMM 74
Query: 422 MSKNVDFVVHSLKDLPTTLPDGLVIGAVFK 511
++ +D VHSLKD+PT LPDGL +GA+ K
Sbjct: 75 LNGTIDLAVHSLKDIPTKLPDGLKLGAITK 104
>UniRef50_P28789 Cluster: Porphobilinogen deaminase; n=9;
Ascomycota|Rep: Porphobilinogen deaminase -
Saccharomyces cerevisiae (Baker's yeast)
Length = 327
Score = 82.2 bits (194), Expect = 7e-15
Identities = 38/94 (40%), Positives = 62/94 (65%), Gaps = 4/94 (4%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
++ ++A++Q+N V+ ++ YP+ + K+ T+ TLGD++ +PL G K+L TK L D L
Sbjct: 11 RKSKLAVIQSNHVLKLIEEKYPDYDCKVFTLQTLGDQIQFKPLYSFGGKALWTKELEDHL 70
Query: 422 M----SKNVDFVVHSLKDLPTTLPDGLVIGAVFK 511
SK +D +VHSLKD+PT LP+G +G + K
Sbjct: 71 YHDDPSKKLDLIVHSLKDMPTLLPEGFELGGITK 104
>UniRef50_P16616 Cluster: Porphobilinogen deaminase; n=22;
Bacillales|Rep: Porphobilinogen deaminase - Bacillus
subtilis
Length = 313
Score = 81.8 bits (193), Expect = 9e-15
Identities = 36/88 (40%), Positives = 55/88 (62%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
+ ++A+ QT +VI LK P F+I + T GDR++D L +G K L K + AL
Sbjct: 9 RRSKLAMTQTKWVIQKLKEINPSFAFEIKEIVTKGDRIVDVTLSKVGGKGLFVKEIEQAL 68
Query: 422 MSKNVDFVVHSLKDLPTTLPDGLVIGAV 505
+++ +D VHS+KD+P LP+GLVIG +
Sbjct: 69 LNEEIDMAVHSMKDMPAVLPEGLVIGCI 96
>UniRef50_Q3E1E4 Cluster: Porphobilinogen deaminase; n=3;
Chloroflexi (class)|Rep: Porphobilinogen deaminase -
Chloroflexus aurantiacus J-10-fl
Length = 324
Score = 79.8 bits (188), Expect = 4e-14
Identities = 38/83 (45%), Positives = 54/83 (65%)
Frame = +2
Query: 254 VALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKN 433
+A VQ+ +V D+L+ +P E ++ ++T GDRVLD L +G+K L K L AL++
Sbjct: 13 LARVQSVWVADALRTAFPSLEVELRIISTTGDRVLDVALSAVGDKGLFVKELEHALLASE 72
Query: 434 VDFVVHSLKDLPTTLPDGLVIGA 502
VD VHS KD+PT PDGLV+ A
Sbjct: 73 VDLCVHSAKDMPTATPDGLVLAA 95
>UniRef50_Q5KWK6 Cluster: Porphobilinogen deaminase; n=32;
Bacillales|Rep: Porphobilinogen deaminase - Geobacillus
kaustophilus
Length = 309
Score = 79.0 bits (186), Expect = 6e-14
Identities = 38/88 (43%), Positives = 55/88 (62%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
+ ++AL QT +VI+ LK+ F++ + T GDRVLD L +G K L K + L
Sbjct: 9 RRSKLALTQTKWVINELKQLGAPFTFEVKEIVTKGDRVLDVTLSKVGGKGLFVKEIEHEL 68
Query: 422 MSKNVDFVVHSLKDLPTTLPDGLVIGAV 505
++ +D VHS+KD+P LP+GLVIGAV
Sbjct: 69 LAGGIDMAVHSMKDMPAVLPEGLVIGAV 96
>UniRef50_Q7U5C2 Cluster: Porphobilinogen deaminase; n=24;
Bacteria|Rep: Porphobilinogen deaminase - Synechococcus
sp. (strain WH8102)
Length = 317
Score = 78.6 bits (185), Expect = 9e-14
Identities = 36/88 (40%), Positives = 55/88 (62%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
+ ++A+VQTN+V L++ +P + M T GD++LD L IG+K L TK L +
Sbjct: 11 RRSQLAMVQTNWVKAELEKAHPGLTITVEAMATQGDKILDVALAKIGDKGLFTKELEAQM 70
Query: 422 MSKNVDFVVHSLKDLPTTLPDGLVIGAV 505
+ + VHSLKDLPT LP+GL++G +
Sbjct: 71 LVGRAEIAVHSLKDLPTNLPEGLMLGCI 98
>UniRef50_Q92HR5 Cluster: Porphobilinogen deaminase; n=9;
Rickettsia|Rep: Porphobilinogen deaminase - Rickettsia
conorii
Length = 351
Score = 78.6 bits (185), Expect = 9e-14
Identities = 37/86 (43%), Positives = 56/86 (65%)
Frame = +2
Query: 254 VALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKN 433
+AL+ TN VI +K+ +P+ +IV + T GD + ++PL IG K+L K + AL+ K
Sbjct: 14 LALIHTNLVIQQIKQFFPDINCEIVPIITSGDLIQNKPLYDIGGKALFLKEIEQALLDKK 73
Query: 434 VDFVVHSLKDLPTTLPDGLVIGAVFK 511
+D VHSLKD+P +P+ LVI AV +
Sbjct: 74 IDLAVHSLKDVPGRMPEPLVIAAVLE 99
>UniRef50_Q6C097 Cluster: Porphobilinogen deaminase; n=10;
Ascomycota|Rep: Porphobilinogen deaminase - Yarrowia
lipolytica (Candida lipolytica)
Length = 338
Score = 78.2 bits (184), Expect = 1e-13
Identities = 40/93 (43%), Positives = 58/93 (62%), Gaps = 5/93 (5%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
++ ++ALVQT V LK+ +P+ F ++ +TTLGD+V +PL K+L TK L L
Sbjct: 24 RKSKLALVQTQHVAAMLKKVHPDYSFPVLGLTTLGDQVQSKPLYSFDGKALWTKELETLL 83
Query: 422 MSK-----NVDFVVHSLKDLPTTLPDGLVIGAV 505
+ K D +VHSLKD+PT LPDG +GA+
Sbjct: 84 LEKVPGFDQQDIIVHSLKDMPTVLPDGCELGAI 116
>UniRef50_Q9RRY0 Cluster: Porphobilinogen deaminase; n=4;
Deinococci|Rep: Porphobilinogen deaminase - Deinococcus
radiodurans
Length = 309
Score = 77.8 bits (183), Expect = 1e-13
Identities = 38/88 (43%), Positives = 57/88 (64%), Gaps = 2/88 (2%)
Frame = +2
Query: 254 VALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLD--QPLPXIGEKSLXTKXLXDALMS 427
+AL QT +V+ LK +PE +F+I T++T GDR + + L G+K K + +AL++
Sbjct: 13 LALAQTRWVVARLKEEWPETDFRIQTISTKGDRNRESLEQLAQKGDKGFWVKEIEEALLA 72
Query: 428 KNVDFVVHSLKDLPTTLPDGLVIGAVFK 511
K +D VHSLKDLPT P+GL I ++ K
Sbjct: 73 KKIDIAVHSLKDLPTEQPEGLEISSIPK 100
>UniRef50_O66621 Cluster: Porphobilinogen deaminase; n=2; Aquifex
aeolicus|Rep: Porphobilinogen deaminase - Aquifex
aeolicus
Length = 304
Score = 77.8 bits (183), Expect = 1e-13
Identities = 37/90 (41%), Positives = 59/90 (65%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
++ ++AL Q N+V D L++++ E ++V +TT GD++ D PL IG K L K + AL
Sbjct: 8 RKSKLALWQANYVKDFLEKHWGV-EVELVKITTTGDKITDVPLAKIGGKGLFVKEIEKAL 66
Query: 422 MSKNVDFVVHSLKDLPTTLPDGLVIGAVFK 511
+ ++D VHSLKD+P +P GL +GA+ K
Sbjct: 67 LEGSIDLAVHSLKDVPMVIPKGLKLGAITK 96
>UniRef50_Q1Q7D2 Cluster: Strongly similar to hydroxymethylbilane
synthase; n=1; Candidatus Kuenenia stuttgartiensis|Rep:
Strongly similar to hydroxymethylbilane synthase -
Candidatus Kuenenia stuttgartiensis
Length = 319
Score = 77.0 bits (181), Expect = 3e-13
Identities = 37/87 (42%), Positives = 56/87 (64%)
Frame = +2
Query: 251 RVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSK 430
++AL QTN+VI LK+ P EF+I ++T GD++ D PL +G + TK L AL+ +
Sbjct: 18 KLALTQTNWVISELKKLNPGVEFEIKKISTSGDKITDVPLSRLGGVGVFTKELEVALIKE 77
Query: 431 NVDFVVHSLKDLPTTLPDGLVIGAVFK 511
+D VHS KD+PT + + L +GA+ K
Sbjct: 78 KIDLAVHSAKDIPTEVSEKLTLGAMPK 104
>UniRef50_Q0EVH8 Cluster: Porphobilinogen deaminase; n=2;
Thermoanaerobacter ethanolicus|Rep: Porphobilinogen
deaminase - Thermoanaerobacter ethanolicus X514
Length = 299
Score = 76.6 bits (180), Expect = 3e-13
Identities = 36/90 (40%), Positives = 56/90 (62%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
+ +AL QT VI+ +K+ + EF+IV +TT GD ++D+P+ IG K + K + AL
Sbjct: 10 RSSELALKQTAMVINEIKKFRQDFEFEIVKITTQGDALIDKPVSEIGGKGVFVKEIESAL 69
Query: 422 MSKNVDFVVHSLKDLPTTLPDGLVIGAVFK 511
+ +D VHS+KD+P +P GL + AV K
Sbjct: 70 LKGEIDMAVHSMKDMPYEIPKGLKLMAVLK 99
>UniRef50_Q8XWW3 Cluster: Porphobilinogen deaminase; n=71;
Proteobacteria|Rep: Porphobilinogen deaminase -
Ralstonia solanacearum (Pseudomonas solanacearum)
Length = 334
Score = 76.6 bits (180), Expect = 3e-13
Identities = 37/90 (41%), Positives = 54/90 (60%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
+E R+A+ Q +V +L++ YP + I+ MTT GD++LD+ L +G K L K L AL
Sbjct: 27 RESRLAMWQAEYVRAALQKYYPACDVSILGMTTRGDQILDRSLAKVGGKGLFVKELEVAL 86
Query: 422 MSKNVDFVVHSLKDLPTTLPDGLVIGAVFK 511
D VHSLKD+P LP G V+ A+ +
Sbjct: 87 AEGRADLAVHSLKDVPMELPPGFVLSAILE 116
>UniRef50_Q2LQU2 Cluster: Porphobilinogen deaminase; n=1; Syntrophus
aciditrophicus SB|Rep: Porphobilinogen deaminase -
Syntrophus aciditrophicus (strain SB)
Length = 306
Score = 76.2 bits (179), Expect = 5e-13
Identities = 39/84 (46%), Positives = 50/84 (59%)
Frame = +2
Query: 254 VALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKN 433
+AL QT + L+ YPE +IV + T GD D PL IG K L K + +AL++
Sbjct: 10 LALTQTRQIAARLQGQYPEMHLEIVVIKTSGDIQKDVPLAKIGGKGLFIKEIEEALLAGT 69
Query: 434 VDFVVHSLKDLPTTLPDGLVIGAV 505
VD VHS+KDLP LP+GL I AV
Sbjct: 70 VDLAVHSMKDLPAELPEGLQIAAV 93
>UniRef50_Q8KCJ4 Cluster: Porphobilinogen deaminase; n=11;
Chlorobiaceae|Rep: Porphobilinogen deaminase -
Chlorobium tepidum
Length = 312
Score = 76.2 bits (179), Expect = 5e-13
Identities = 37/86 (43%), Positives = 51/86 (59%)
Frame = +2
Query: 254 VALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKN 433
+AL Q F L R++PE + + T GD +LD PL IG+ L TK + L++K
Sbjct: 14 LALWQAEFTKAELSRHFPELNITLKLVKTTGDVLLDSPLSKIGDMGLFTKDIEKHLLAKE 73
Query: 434 VDFVVHSLKDLPTTLPDGLVIGAVFK 511
+D VHSLKD+PT P+GLVI + K
Sbjct: 74 IDLAVHSLKDVPTGTPEGLVISSFTK 99
>UniRef50_Q1QEM1 Cluster: Porphobilinogen deaminase; n=2;
Psychrobacter|Rep: Porphobilinogen deaminase -
Psychrobacter cryohalolentis (strain K5)
Length = 345
Score = 75.8 bits (178), Expect = 6e-13
Identities = 37/90 (41%), Positives = 50/90 (55%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
++ +AL Q + + L YPE ++ + T GD++LD PL IG K L K L AL
Sbjct: 17 RQSPLALWQAEHIRNRLLALYPEMTINLLKIVTKGDKILDTPLAKIGGKGLFVKELEQAL 76
Query: 422 MSKNVDFVVHSLKDLPTTLPDGLVIGAVFK 511
K D VHSLKD+P LP+GL +G K
Sbjct: 77 YDKQADIAVHSLKDVPMDLPEGLTLGVYCK 106
>UniRef50_A1WVT9 Cluster: Porphobilinogen deaminase; n=5;
Gammaproteobacteria|Rep: Porphobilinogen deaminase -
Halorhodospira halophila (strain DSM 244 / SL1)
(Ectothiorhodospirahalophila (strain DSM 244 / SL1))
Length = 310
Score = 74.9 bits (176), Expect = 1e-12
Identities = 35/88 (39%), Positives = 52/88 (59%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
+ ++A+ Q + L+R +P E ++V M+T GD +LDQPL IG K L K L D +
Sbjct: 11 RRSQLAMWQAEHIAAELQRLHPGLEVELVPMSTRGDEILDQPLARIGGKGLFMKELEDGM 70
Query: 422 MSKNVDFVVHSLKDLPTTLPDGLVIGAV 505
+ D VHS+KD+P LP+G + AV
Sbjct: 71 LRGEADLAVHSMKDIPWRLPEGFDLAAV 98
>UniRef50_A3CL78 Cluster: Porphobilinogen deaminase, putative; n=1;
Streptococcus sanguinis SK36|Rep: Porphobilinogen
deaminase, putative - Streptococcus sanguinis (strain
SK36)
Length = 306
Score = 74.5 bits (175), Expect = 1e-12
Identities = 33/88 (37%), Positives = 55/88 (62%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
++ ++A+ QT ++D LK +PE++F +V TT GDR+ L IG K + K + AL
Sbjct: 9 RKSKLAMTQTQQLVDQLKALHPERDFVLVPYTTKGDRLTHVSLQEIGGKGVFVKEIERAL 68
Query: 422 MSKNVDFVVHSLKDLPTTLPDGLVIGAV 505
++ ++ VHSLKD+P L +G +GA+
Sbjct: 69 LAGEINMAVHSLKDMPAKLAEGCALGAI 96
>UniRef50_Q9KVM1 Cluster: Porphobilinogen deaminase; n=57;
Gammaproteobacteria|Rep: Porphobilinogen deaminase -
Vibrio cholerae
Length = 311
Score = 74.5 bits (175), Expect = 1e-12
Identities = 35/83 (42%), Positives = 50/83 (60%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
++ +AL Q N+V D+L +P + ++VTM T GD +LD PL +G K L K L A+
Sbjct: 11 RQSPLALWQANYVKDALMAAHPGLQVELVTMVTRGDVILDTPLAKVGGKGLFVKELEIAM 70
Query: 422 MSKNVDFVVHSLKDLPTTLPDGL 490
+ D VHS+KD+P PDGL
Sbjct: 71 LEGRADLAVHSMKDVPVDFPDGL 93
>UniRef50_Q602K3 Cluster: Porphobilinogen deaminase; n=26; cellular
organisms|Rep: Porphobilinogen deaminase - Methylococcus
capsulatus
Length = 322
Score = 73.7 bits (173), Expect = 2e-12
Identities = 35/97 (36%), Positives = 55/97 (56%), Gaps = 2/97 (2%)
Frame = +2
Query: 227 HSRRLQEER--VALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXT 400
H+ R+ + +AL Q +V L+ +P+ ++V MTT GD++LD PL +G K L
Sbjct: 16 HTLRIATRKSPLALWQAEYVASRLRAAHPDLRVELVGMTTRGDKLLDAPLAKVGGKGLFV 75
Query: 401 KXLXDALMSKNVDFVVHSLKDLPTTLPDGLVIGAVFK 511
K L L+ D VHS+KD+P P+GL + A+ +
Sbjct: 76 KELEQGLLEGRADIAVHSMKDVPVEFPEGLHLAAILE 112
>UniRef50_Q75DY0 Cluster: Porphobilinogen deaminase; n=7;
Ascomycota|Rep: Porphobilinogen deaminase - Ashbya
gossypii (Yeast) (Eremothecium gossypii)
Length = 326
Score = 73.7 bits (173), Expect = 2e-12
Identities = 35/94 (37%), Positives = 58/94 (61%), Gaps = 4/94 (4%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
+ ++A++Q+ V + ++R +P ++ TLGD+V +PL G K+L TK L D L
Sbjct: 11 RRSKLAVIQSESVKEIVQREFPNYTCTVLAKQTLGDQVQSKPLYAFGGKALWTKELEDLL 70
Query: 422 ----MSKNVDFVVHSLKDLPTTLPDGLVIGAVFK 511
+ + +D +VHSLKD+PT LP+G +GA+ K
Sbjct: 71 YEEDLDQRIDMIVHSLKDMPTQLPEGFELGAITK 104
>UniRef50_Q5ZRY6 Cluster: Porphobilinogen deaminase; n=5; Legionella
pneumophila|Rep: Porphobilinogen deaminase - Legionella
pneumophila subsp. pneumophila (strain Philadelphia 1
/ATCC 33152 / DSM 7513)
Length = 309
Score = 72.9 bits (171), Expect = 4e-12
Identities = 36/90 (40%), Positives = 51/90 (56%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
++ +AL Q N V + L + +P +++ M T GDR L L G K L K L +AL
Sbjct: 11 RQSPLALWQANHVREMLVKQWPNLSIELLPMITSGDRFLKDKLLSAGGKGLFVKELEEAL 70
Query: 422 MSKNVDFVVHSLKDLPTTLPDGLVIGAVFK 511
+ K D VHS KD+P LPDGL++ A+ K
Sbjct: 71 LDKRADLAVHSTKDMPAQLPDGLLLTAICK 100
>UniRef50_Q180R9 Cluster: Porphobilinogen deaminase; n=3;
Clostridium|Rep: Porphobilinogen deaminase - Clostridium
difficile (strain 630)
Length = 301
Score = 72.1 bits (169), Expect = 7e-12
Identities = 33/79 (41%), Positives = 50/79 (63%)
Frame = +2
Query: 254 VALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKN 433
+AL+QT +VI+ LK+ YPE F+I + T GD + + L IG+K L K + L+
Sbjct: 12 LALIQTEWVINELKKKYPEISFEIKIIKTKGDLIQNVSLDKIGDKGLFVKEIEQQLLDGK 71
Query: 434 VDFVVHSLKDLPTTLPDGL 490
+D VHS+KD+P+ L +GL
Sbjct: 72 IDIAVHSMKDMPSYLANGL 90
>UniRef50_Q0EWI8 Cluster: Porphobilinogen deaminase; n=2;
Proteobacteria|Rep: Porphobilinogen deaminase -
Mariprofundus ferrooxydans PV-1
Length = 333
Score = 72.1 bits (169), Expect = 7e-12
Identities = 36/98 (36%), Positives = 55/98 (56%), Gaps = 1/98 (1%)
Frame = +2
Query: 215 NETKHSR-RLQEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKS 391
N H R + +AL Q ++ L++ P+ ++V + T GD++LD PL +G K
Sbjct: 22 NSVPHIRIATRRSPLALWQAEYIAAELEKMSPDVTTELVKIVTRGDKILDVPLAKVGGKG 81
Query: 392 LXTKXLXDALMSKNVDFVVHSLKDLPTTLPDGLVIGAV 505
L TK + +AL D VHS+KD+PT LP+G I A+
Sbjct: 82 LFTKEIDEALFDGRADVAVHSMKDVPTQLPEGTSIRAL 119
>UniRef50_Q92LH7 Cluster: Porphobilinogen deaminase; n=53; cellular
organisms|Rep: Porphobilinogen deaminase - Rhizobium
meliloti (Sinorhizobium meliloti)
Length = 309
Score = 72.1 bits (169), Expect = 7e-12
Identities = 37/85 (43%), Positives = 54/85 (63%), Gaps = 2/85 (2%)
Frame = +2
Query: 254 VALVQTNFVIDSLKRNY--PEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMS 427
+A+ QT+ D L + P + F+IV ++T GDR+ D+ L IG K L T+ L L+S
Sbjct: 15 LAMAQTHETRDRLAAAHGLPPEMFEIVILSTKGDRITDRSLAEIGGKGLFTEELEQQLLS 74
Query: 428 KNVDFVVHSLKDLPTTLPDGLVIGA 502
++DF VHS KD+PT LP+GL + A
Sbjct: 75 GDLDFAVHSSKDMPTKLPEGLFLSA 99
>UniRef50_Q5WEP5 Cluster: Porphobilinogen deaminase; n=2;
Firmicutes|Rep: Porphobilinogen deaminase - Bacillus
clausii (strain KSM-K16)
Length = 311
Score = 72.1 bits (169), Expect = 7e-12
Identities = 35/88 (39%), Positives = 53/88 (60%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
+ ++AL QTN+VID LK+ EF++ + T GDR+LD L +G K L K + AL
Sbjct: 9 RRSKLALTQTNWVIDQLKQLGVPYEFEVKEIVTKGDRILDVTLSKVGGKGLFVKEIEAAL 68
Query: 422 MSKNVDFVVHSLKDLPTTLPDGLVIGAV 505
S +D VHS+KD+P+ L + + A+
Sbjct: 69 RSGEIDVAVHSMKDVPSELLEEFTLAAI 96
>UniRef50_Q1EPC8 Cluster: Porphobilinogen deaminase, chloroplast
(Hydroxymethylbilane synthase) (Pre-uroporphyrinogen
synthase), putative; n=1; Musa acuminata|Rep:
Porphobilinogen deaminase, chloroplast
(Hydroxymethylbilane synthase) (Pre-uroporphyrinogen
synthase), putative - Musa acuminata (Banana)
Length = 328
Score = 71.3 bits (167), Expect = 1e-11
Identities = 36/90 (40%), Positives = 53/90 (58%), Gaps = 4/90 (4%)
Frame = +2
Query: 239 LQEERVALVQTNFVIDSLKRNYPEKE----FKIVTMTTLGDRVLDQPLPXIGEKSLXTKX 406
L++ +AL Q D LK + E +I+ + T GD +LD+PL IG K L TK
Sbjct: 53 LRDSDLALAQARETRDKLKAAHSELAEEGAVEIIIIKTTGDMILDKPLADIGGKGLFTKE 112
Query: 407 LXDALMSKNVDFVVHSLKDLPTTLPDGLVI 496
+ DAL+ +D VHS+KD+PT LP+G ++
Sbjct: 113 IDDALLQGRIDIAVHSMKDVPTYLPEGTIL 142
>UniRef50_A0RXB2 Cluster: Porphobilinogen deaminase; n=2;
Thermoprotei|Rep: Porphobilinogen deaminase -
Cenarchaeum symbiosum
Length = 311
Score = 70.9 bits (166), Expect = 2e-11
Identities = 37/85 (43%), Positives = 51/85 (60%)
Frame = +2
Query: 251 RVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSK 430
R++L QT V+D+LK PE E+K+ + T GD D+PL I +K + K + A+
Sbjct: 12 RLSLAQTGHVLDALKEANPEDEYKVRRIKTQGDTD-DRPLFAIDQKGIFEKEIDRAVSEG 70
Query: 431 NVDFVVHSLKDLPTTLPDGLVIGAV 505
DF VHSLKD+PT L GLV+ V
Sbjct: 71 GADFAVHSLKDVPTELAPGLVLACV 95
>UniRef50_Q0GL46 Cluster: Porphobilinogen deaminase; n=3;
Lactobacillus reuteri|Rep: Porphobilinogen deaminase -
Lactobacillus reuteri
Length = 305
Score = 70.5 bits (165), Expect = 2e-11
Identities = 35/87 (40%), Positives = 51/87 (58%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
++ ++A+ QT VI SLK +P +F+I + T GDR L IG K + K + + L
Sbjct: 10 RKSKLAMAQTKLVIASLKELFPTTQFEIKNVITEGDRNQQASLAKIGGKGVFVKEIEEEL 69
Query: 422 MSKNVDFVVHSLKDLPTTLPDGLVIGA 502
+ +DF VHSLKD+ LPD L +GA
Sbjct: 70 KNCTIDFAVHSLKDVMPVLPDELTLGA 96
>UniRef50_A6GB01 Cluster: Porphobilinogen deaminase; n=1;
Plesiocystis pacifica SIR-1|Rep: Porphobilinogen
deaminase - Plesiocystis pacifica SIR-1
Length = 322
Score = 70.5 bits (165), Expect = 2e-11
Identities = 35/85 (41%), Positives = 52/85 (61%), Gaps = 2/85 (2%)
Frame = +2
Query: 254 VALVQTNFVIDSLKRNYPEK--EFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMS 427
+AL Q N + D L + + E ++V + T GDRV D+PL +G L K L D L++
Sbjct: 20 LALWQANMIRDRLLAAWGAQGLEVELVRVVTKGDRVTDRPLNQVGGMGLFVKGLEDKLLA 79
Query: 428 KNVDFVVHSLKDLPTTLPDGLVIGA 502
+DF VHS+KD+P TLP+GL + +
Sbjct: 80 GEIDFAVHSMKDMPGTLPEGLTLAS 104
>UniRef50_A5ZY88 Cluster: Putative uncharacterized protein; n=3;
Bacteria|Rep: Putative uncharacterized protein -
Ruminococcus obeum ATCC 29174
Length = 312
Score = 70.5 bits (165), Expect = 2e-11
Identities = 33/83 (39%), Positives = 51/83 (61%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
+E R+A++Q+ V D +K +P + +I+TM T GD++LD+ L +G K L K L AL
Sbjct: 15 RESRLAVLQSEMVRDYIKEQHPGLDVEILTMKTTGDKILDRTLDKVGGKGLFVKELDKAL 74
Query: 422 MSKNVDFVVHSLKDLPTTLPDGL 490
+ VHSLKD+P +P+ L
Sbjct: 75 LEGRTMLSVHSLKDMPMEVPEDL 97
>UniRef50_Q09899 Cluster: Porphobilinogen deaminase; n=1;
Schizosaccharomyces pombe|Rep: Porphobilinogen deaminase
- Schizosaccharomyces pombe (Fission yeast)
Length = 336
Score = 70.1 bits (164), Expect = 3e-11
Identities = 33/93 (35%), Positives = 58/93 (62%), Gaps = 3/93 (3%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGE---KSLXTKXLX 412
++ ++A++Q+ + + L+++YP EF I++ T+GD +L + L KSL T+ L
Sbjct: 12 RKSKLAVIQSEIIREELEKHYPHLEFPIISRDTIGDEILSKALFEFKRQLAKSLWTRELE 71
Query: 413 DALMSKNVDFVVHSLKDLPTTLPDGLVIGAVFK 511
L++ +VHSLKDLP+ +PDG+VI + K
Sbjct: 72 ALLVTNQCRILVHSLKDLPSEMPDGMVIACIPK 104
>UniRef50_P46355 Cluster: Porphobilinogen deaminase; n=144;
Bacteria|Rep: Porphobilinogen deaminase - Yersinia
pestis
Length = 313
Score = 69.3 bits (162), Expect = 5e-11
Identities = 33/83 (39%), Positives = 49/83 (59%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
++ +AL Q ++V L+ N+P + ++V M T GD +LD PL +G K L K L AL
Sbjct: 11 RQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKGLFVKELELAL 70
Query: 422 MSKNVDFVVHSLKDLPTTLPDGL 490
+ D VHS+KD+P P+GL
Sbjct: 71 LDGRADIAVHSMKDVPIAFPEGL 93
>UniRef50_O94048 Cluster: Porphobilinogen deaminase; n=4;
Ascomycota|Rep: Porphobilinogen deaminase - Candida
albicans (Yeast)
Length = 340
Score = 69.3 bits (162), Expect = 5e-11
Identities = 35/95 (36%), Positives = 56/95 (58%), Gaps = 5/95 (5%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
++ ++A+VQ+ V ++ +P I+ ++TLGD+V QPL G KSL TK L L
Sbjct: 19 RKSKLAVVQSEIVKKVIEDTFPNLSCSILALSTLGDKVQTQPLYTFGGKSLWTKELEILL 78
Query: 422 MSK-----NVDFVVHSLKDLPTTLPDGLVIGAVFK 511
+ +D +VHSLKD+PT LP+ +G +F+
Sbjct: 79 LDSVDEFPKLDLIVHSLKDMPTNLPEEFELGCIFQ 113
>UniRef50_A6Q7Y4 Cluster: Porphobilinogen deaminase; n=1; Sulfurovum
sp. NBC37-1|Rep: Porphobilinogen deaminase - Sulfurovum
sp. (strain NBC37-1)
Length = 323
Score = 68.9 bits (161), Expect = 7e-11
Identities = 31/84 (36%), Positives = 53/84 (63%)
Frame = +2
Query: 254 VALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKN 433
+AL Q + + ++ +PE ++ +T+ GD++LD+PL +G K TK L D +++ N
Sbjct: 13 LALWQAYHIKERIETAFPEVRVELNEITSKGDKILDKPLALVGGKGHFTKELEDEMIAGN 72
Query: 434 VDFVVHSLKDLPTTLPDGLVIGAV 505
VHSLKD+PT +P+GL + A+
Sbjct: 73 AHLAVHSLKDVPTYIPEGLELCAI 96
>UniRef50_A6LKX0 Cluster: Porphobilinogen deaminase; n=1;
Thermosipho melanesiensis BI429|Rep: Porphobilinogen
deaminase - Thermosipho melanesiensis BI429
Length = 279
Score = 68.5 bits (160), Expect = 9e-11
Identities = 31/90 (34%), Positives = 53/90 (58%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
++ ++AL+QT V++ LK P +F+I + T GDR L P+ IG K + + +
Sbjct: 8 RKSKLALIQTQLVVNKLKELLPNIDFEITPVVTKGDR-LKTPIDKIGGKGVFVSDIEKLI 66
Query: 422 MSKNVDFVVHSLKDLPTTLPDGLVIGAVFK 511
+ +D +HS+KDLP+ +PD L + +V K
Sbjct: 67 LDDKLDIAIHSMKDLPSKIPDKLFLTSVLK 96
>UniRef50_Q6BM23 Cluster: Porphobilinogen deaminase; n=6;
Saccharomycetales|Rep: Porphobilinogen deaminase -
Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
Length = 361
Score = 67.3 bits (157), Expect = 2e-10
Identities = 32/93 (34%), Positives = 56/93 (60%), Gaps = 5/93 (5%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
++ ++A+VQ+ V + + +PE ++ ++TLGD+V +PL G K+L TK L L
Sbjct: 24 RKSKLAVVQSEIVKECIVEKFPELSCSVLALSTLGDKVQSKPLYSFGGKALWTKELEILL 83
Query: 422 MSK-----NVDFVVHSLKDLPTTLPDGLVIGAV 505
+ + +D +VHSLKD+PT LP+ +G +
Sbjct: 84 LEQVEEYPRLDLIVHSLKDIPTNLPEEFELGCI 116
>UniRef50_Q57B08 Cluster: Porphobilinogen deaminase; n=7;
Rhizobiales|Rep: Porphobilinogen deaminase - Brucella
abortus
Length = 314
Score = 67.3 bits (157), Expect = 2e-10
Identities = 29/62 (46%), Positives = 40/62 (64%)
Frame = +2
Query: 305 PEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKNVDFVVHSLKDLPTTLPD 484
PE +I+ M+T GDR+ D+PL +G K L T+ + AL +D VHS KD+PT LP+
Sbjct: 39 PEDAIEILPMSTAGDRIQDRPLSEVGGKGLFTEEIEQALKDGRIDIAVHSTKDMPTALPE 98
Query: 485 GL 490
GL
Sbjct: 99 GL 100
>UniRef50_Q2S2A6 Cluster: Porphobilinogen deaminase; n=1;
Salinibacter ruber DSM 13855|Rep: Porphobilinogen
deaminase - Salinibacter ruber (strain DSM 13855)
Length = 323
Score = 66.9 bits (156), Expect = 3e-10
Identities = 35/84 (41%), Positives = 50/84 (59%)
Frame = +2
Query: 254 VALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKN 433
+AL Q N V L+ E + T+TT GD D P+ IG++++ TK L AL+
Sbjct: 16 LALRQANVVRSRLEAAGHRVELE--TITTRGDEATDTPISEIGDEAVFTKELDRALLQGG 73
Query: 434 VDFVVHSLKDLPTTLPDGLVIGAV 505
VD VHSLKD+P+T+P GL + A+
Sbjct: 74 VDLAVHSLKDIPSTVPSGLALAAI 97
>UniRef50_Q59293 Cluster: Porphobilinogen deaminase; n=5;
Clostridium|Rep: Porphobilinogen deaminase - Clostridium
josui
Length = 291
Score = 66.5 bits (155), Expect = 4e-10
Identities = 27/76 (35%), Positives = 50/76 (65%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
++ ++A++Q+ ++ ++++ P+ E +++TM T GD++LD+ L I K L K L +AL
Sbjct: 9 RDSKLAIIQSELIMSAIRKYDPDIELELITMKTTGDKILDKTLDKIEGKGLFVKELDNAL 68
Query: 422 MSKNVDFVVHSLKDLP 469
+ VD VHS KD+P
Sbjct: 69 YNNEVDITVHSYKDMP 84
>UniRef50_Q7M8L2 Cluster: Porphobilinogen deaminase; n=6;
Bacteria|Rep: Porphobilinogen deaminase - Wolinella
succinogenes
Length = 311
Score = 65.7 bits (153), Expect = 6e-10
Identities = 31/84 (36%), Positives = 49/84 (58%)
Frame = +2
Query: 254 VALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKN 433
+AL Q +V L+R + ++ + T GD++LD PL +G K L TK L + ++
Sbjct: 13 LALWQAEYVKAELERAHEGLSVELKIVKTKGDKILDVPLAKVGGKGLFTKELEEMMLQGE 72
Query: 434 VDFVVHSLKDLPTTLPDGLVIGAV 505
+D VHSLKD+P L +GL + A+
Sbjct: 73 IDLAVHSLKDVPVELIEGLTLSAI 96
>UniRef50_Q97MU4 Cluster: Porphobilinogen deaminase; n=12;
Clostridium|Rep: Porphobilinogen deaminase - Clostridium
acetobutylicum
Length = 291
Score = 65.7 bits (153), Expect = 6e-10
Identities = 35/88 (39%), Positives = 51/88 (57%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
++ ++A VQT +I+ LK Y K++ M TLGD++LD+ L IG K L K + L
Sbjct: 8 RKSKLAQVQTELIINVLKDKYGISSEKLL-METLGDKILDKSLADIGGKGLFIKDIERIL 66
Query: 422 MSKNVDFVVHSLKDLPTTLPDGLVIGAV 505
+ D VHS+KD+P +PD I AV
Sbjct: 67 LEDKADAAVHSMKDVPFEVPDMFEIAAV 94
>UniRef50_Q43316 Cluster: Porphobilinogen deaminase, chloroplast
precursor; n=12; Eukaryota|Rep: Porphobilinogen
deaminase, chloroplast precursor - Arabidopsis thaliana
(Mouse-ear cress)
Length = 382
Score = 65.7 bits (153), Expect = 6e-10
Identities = 33/85 (38%), Positives = 51/85 (60%), Gaps = 4/85 (4%)
Frame = +2
Query: 254 VALVQTNFVIDSLKRNYPEK----EFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
+AL Q + LK+ +PE I + T GD++L QPL IG K L TK + +AL
Sbjct: 84 LALAQAYETREKLKKKHPELVEDGAIHIEIIKTTGDKILSQPLADIGGKGLFTKEIDEAL 143
Query: 422 MSKNVDFVVHSLKDLPTTLPDGLVI 496
++ ++D VHS+KD+PT LP+ ++
Sbjct: 144 INGHIDIAVHSMKDVPTYLPEKTIL 168
>UniRef50_Q0ATQ1 Cluster: Porphobilinogen deaminase; n=3;
Alphaproteobacteria|Rep: Porphobilinogen deaminase -
Maricaulis maris (strain MCS10)
Length = 321
Score = 64.9 bits (151), Expect = 1e-09
Identities = 29/68 (42%), Positives = 44/68 (64%)
Frame = +2
Query: 308 EKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKNVDFVVHSLKDLPTTLPDG 487
E+ F I+ + + GDR+ D+ L G K L TK + +A + F VHS+KD+PT LPDG
Sbjct: 41 ERCFPILGLVSTGDRIQDRTLIEAGGKGLFTKEIDEAQLDGRAAFAVHSMKDVPTVLPDG 100
Query: 488 LVIGAVFK 511
+V+GA+ +
Sbjct: 101 IVLGALLE 108
>UniRef50_A6EES9 Cluster: Porphobilinogen deaminase; n=1; Pedobacter
sp. BAL39|Rep: Porphobilinogen deaminase - Pedobacter
sp. BAL39
Length = 526
Score = 64.9 bits (151), Expect = 1e-09
Identities = 37/84 (44%), Positives = 47/84 (55%)
Frame = +2
Query: 254 VALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKN 433
+AL Q NF+ D L E E KI+ T GD++L+ L + K TK L + L+
Sbjct: 13 LALWQANFIKDRLAEIGAEAELKIIK--TQGDKILNLRLDKLEGKGFFTKELEEELLGGT 70
Query: 434 VDFVVHSLKDLPTTLPDGLVIGAV 505
+D VHS KDLPTT P GL I AV
Sbjct: 71 IDIAVHSHKDLPTTHPAGLTIAAV 94
>UniRef50_O26960 Cluster: Probable porphobilinogen deaminase; n=2;
Methanobacteriaceae|Rep: Probable porphobilinogen
deaminase - Methanobacterium thermoautotrophicum
Length = 289
Score = 64.9 bits (151), Expect = 1e-09
Identities = 39/86 (45%), Positives = 52/86 (60%), Gaps = 1/86 (1%)
Frame = +2
Query: 251 RVALVQTNFVIDSLKRNYPEK-EFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMS 427
R+ALVQTN VI+ L EK E KI+ T GDR+ D L + + L T+ L A+++
Sbjct: 9 RLALVQTNHVIEMLSEVCKEKIEKKIIK--TKGDRIRDSQLYSMDSRGLFTRELDMAVLN 66
Query: 428 KNVDFVVHSLKDLPTTLPDGLVIGAV 505
+ VD VHSLKD+P+ L L I AV
Sbjct: 67 EEVDLAVHSLKDVPSDLDPDLAIAAV 92
>UniRef50_Q5FPS5 Cluster: Porphobilinogen deaminase; n=3;
Acetobacteraceae|Rep: Porphobilinogen deaminase -
Gluconobacter oxydans (Gluconobacter suboxydans)
Length = 357
Score = 63.7 bits (148), Expect = 3e-09
Identities = 39/90 (43%), Positives = 49/90 (54%), Gaps = 4/90 (4%)
Frame = +2
Query: 254 VALVQTNFVIDSLKRNYPEKE----FKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
+ALVQT + L R P F+ ++T GDR L Q L IG K L K + +AL
Sbjct: 52 LALVQTRNFLTRLTRFCPVLRDMGAFQEYQISTEGDRNLVQRLAEIGGKGLFAKEIHEAL 111
Query: 422 MSKNVDFVVHSLKDLPTTLPDGLVIGAVFK 511
+ +DF VHSLKDL T LP GLV+ K
Sbjct: 112 AAGRIDFAVHSLKDLETNLPPGLVLACTLK 141
>UniRef50_Q57989 Cluster: Probable porphobilinogen deaminase; n=6;
Methanococcales|Rep: Probable porphobilinogen deaminase
- Methanococcus jannaschii
Length = 292
Score = 63.7 bits (148), Expect = 3e-09
Identities = 38/97 (39%), Positives = 58/97 (59%), Gaps = 2/97 (2%)
Frame = +2
Query: 251 RVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSK 430
++AL Q N V + LK + E KI+ T GDRVLD+ L IG + TK L A+++
Sbjct: 10 KLALYQANKVAELLKNLGYKVEIKIIKTT--GDRVLDKKLSDIGI-GVFTKELDLAMLNN 66
Query: 431 NVDFVVHSLKDLPTTLPDGLVIGAVFKXXTL--VMLW 535
+D VHSLKD+PT + L++GAV + + +++W
Sbjct: 67 EIDIAVHSLKDIPTIWNENLMVGAVLERDSYHDLLIW 103
>UniRef50_Q8ZYW7 Cluster: Probable porphobilinogen deaminase; n=3;
Pyrobaculum|Rep: Probable porphobilinogen deaminase -
Pyrobaculum aerophilum
Length = 297
Score = 63.3 bits (147), Expect = 3e-09
Identities = 35/91 (38%), Positives = 52/91 (57%)
Frame = +2
Query: 251 RVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSK 430
R++L+QT + +K P +F+I + T GD V D+PL IG K + K + A++
Sbjct: 11 RLSLLQTEEFLAQIKAVEPRVDFEIKIVKTTGDLVQDKPLFQIGVKGIFEKEVNLAVLKG 70
Query: 431 NVDFVVHSLKDLPTTLPDGLVIGAVFKXXTL 523
D +HSLKDLP+ + GLV+ A F TL
Sbjct: 71 EADIAIHSLKDLPSEISPGLVL-AGFSKRTL 100
>UniRef50_A5KJC5 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus torques ATCC 27756|Rep: Putative
uncharacterized protein - Ruminococcus torques ATCC
27756
Length = 307
Score = 62.9 bits (146), Expect = 5e-09
Identities = 30/76 (39%), Positives = 44/76 (57%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
+E R+A+ Q + D ++R +I+TM T GD++LD+ L +G K L K L AL
Sbjct: 10 RESRLAVKQAEIIKDQIRRCDQTILVEIITMKTTGDKILDRSLESVGGKGLFVKELDQAL 69
Query: 422 MSKNVDFVVHSLKDLP 469
+D VHSLKD+P
Sbjct: 70 ADGRIDLAVHSLKDMP 85
>UniRef50_A2BL26 Cluster: Probable porphobilinogen deaminase; n=2;
Thermoprotei|Rep: Probable porphobilinogen deaminase -
Hyperthermus butylicus (strain DSM 5456 / JCM 9403)
Length = 303
Score = 62.9 bits (146), Expect = 5e-09
Identities = 29/82 (35%), Positives = 49/82 (59%)
Frame = +2
Query: 251 RVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSK 430
++++ QT ++++KR P E+++V + T GD D+P IG K L K + A++
Sbjct: 11 KLSIAQTMIALEAIKRVEPSLEYELVIVKTRGDIHQDKPFTAIGGKGLFEKEVNLAVLEG 70
Query: 431 NVDFVVHSLKDLPTTLPDGLVI 496
D VHSLKD+P+ + GLV+
Sbjct: 71 RADIAVHSLKDVPSAISPGLVL 92
>UniRef50_Q1XAN5 Cluster: Putative porphobilinogen deaminase; n=2;
Actinomycetales|Rep: Putative porphobilinogen deaminase
- Streptomyces nodosus subsp. asukaensis
Length = 167
Score = 62.5 bits (145), Expect = 6e-09
Identities = 34/88 (38%), Positives = 51/88 (57%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
+ ++A+ Q+ V D++ + ++V +TT GD + + L IG + L DAL
Sbjct: 20 RRSKLAMAQSGMVADAVSE-VTGRAVELVEVTTYGD-ISREHLAQIGGTGVFVAALRDAL 77
Query: 422 MSKNVDFVVHSLKDLPTTLPDGLVIGAV 505
+ VDF VHSLKDLPT P+GLV+ AV
Sbjct: 78 LRGEVDFAVHSLKDLPTAQPEGLVLAAV 105
>UniRef50_A4CHM3 Cluster: Porphobilinogen deaminase; n=3;
Flavobacteriaceae|Rep: Porphobilinogen deaminase -
Robiginitalea biformata HTCC2501
Length = 315
Score = 62.5 bits (145), Expect = 6e-09
Identities = 34/90 (37%), Positives = 53/90 (58%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
++ +AL Q V D L+ E +V + + GD VLD+PL +G + TK L AL
Sbjct: 10 RDSELALWQAQTVRDRLEAAGHRAE--LVPVKSTGDLVLDKPLYELGITGIFTKTLDVAL 67
Query: 422 MSKNVDFVVHSLKDLPTTLPDGLVIGAVFK 511
+ +++D VHS+KD+PT LP+G+ AV +
Sbjct: 68 LREDIDLAVHSMKDVPTALPEGICQAAVLE 97
>UniRef50_Q7RNI8 Cluster: Porphobilinogen deaminase, putative; n=5;
Plasmodium|Rep: Porphobilinogen deaminase, putative -
Plasmodium yoelii yoelii
Length = 583
Score = 62.1 bits (144), Expect = 8e-09
Identities = 27/62 (43%), Positives = 38/62 (61%)
Frame = +2
Query: 338 TLGDRVLDQPLPXIGEKSLXTKXLXDALMSKNVDFVVHSLKDLPTTLPDGLVIGAVFKXX 517
T GD++LD+ + G K + TK L + L+ NVD VHSLKD+PT LPD + + K
Sbjct: 114 TTGDKILDKTVGSFGGKGIFTKELDEELIKNNVDICVHSLKDIPTVLPDNIHLSCFLKRD 173
Query: 518 TL 523
T+
Sbjct: 174 TI 175
>UniRef50_Q9ABZ8 Cluster: Porphobilinogen deaminase; n=2;
Caulobacter|Rep: Porphobilinogen deaminase - Caulobacter
crescentus (Caulobacter vibrioides)
Length = 322
Score = 62.1 bits (144), Expect = 8e-09
Identities = 28/60 (46%), Positives = 39/60 (65%)
Frame = +2
Query: 323 IVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKNVDFVVHSLKDLPTTLPDGLVIGA 502
++ + T GDR+ D+ L IG K L TK + +AL+ +D VHSLKD+P LP GLV+ A
Sbjct: 49 LIPIVTSGDRIQDRRLMEIGGKGLFTKEIEEALLDGRIDCAVHSLKDMPAELPPGLVLAA 108
>UniRef50_A6C1S2 Cluster: Porphobilinogen deaminase; n=1;
Planctomyces maris DSM 8797|Rep: Porphobilinogen
deaminase - Planctomyces maris DSM 8797
Length = 318
Score = 61.3 bits (142), Expect = 1e-08
Identities = 32/84 (38%), Positives = 46/84 (54%)
Frame = +2
Query: 254 VALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKN 433
+AL Q +V D LK+ E+ +IV +T+ GDR L PL G + T+ + A++
Sbjct: 19 LALWQAYYVSDLLKKQSSERPIEIVHITSEGDRDLTSPLSEFGGLGVFTREVQKAVLDGR 78
Query: 434 VDFVVHSLKDLPTTLPDGLVIGAV 505
D VHSLKDLPT GL + +
Sbjct: 79 ADLAVHSLKDLPTEQAPGLQLAGI 102
>UniRef50_Q7VFE9 Cluster: Porphobilinogen deaminase; n=19;
Epsilonproteobacteria|Rep: Porphobilinogen deaminase -
Helicobacter hepaticus
Length = 321
Score = 60.9 bits (141), Expect = 2e-08
Identities = 33/84 (39%), Positives = 48/84 (57%)
Frame = +2
Query: 254 VALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKN 433
+AL Q ++ LK + +I + T GD++LD PL IG K L TK L + L+SK+
Sbjct: 20 LALWQAEYIKSCLKAQCGLQS-RIQIIKTRGDKILDVPLAKIGGKGLFTKELEEMLLSKD 78
Query: 434 VDFVVHSLKDLPTTLPDGLVIGAV 505
+D VHSLKD+P L + A+
Sbjct: 79 IDLAVHSLKDVPVEFVPELDLAAI 102
>UniRef50_Q0UDH2 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 397
Score = 60.1 bits (139), Expect = 3e-08
Identities = 33/90 (36%), Positives = 49/90 (54%), Gaps = 4/90 (4%)
Frame = +2
Query: 254 VALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGE----KSLXTKXLXDAL 421
+A +Q V +LK +PE+ + I + GDR PL + + KSL T L L
Sbjct: 40 LAQIQARAVAAALKSAHPERTYNICPVVVEGDRDKITPLQQLSQGENAKSLWTGELETML 99
Query: 422 MSKNVDFVVHSLKDLPTTLPDGLVIGAVFK 511
++D +VH LKD+PT LPD L +GA+ +
Sbjct: 100 EKGDLDIIVHCLKDMPTQLPDNLELGAILE 129
>UniRef50_Q8TT56 Cluster: Probable porphobilinogen deaminase; n=6;
Euryarchaeota|Rep: Probable porphobilinogen deaminase -
Methanosarcina acetivorans
Length = 317
Score = 59.7 bits (138), Expect = 4e-08
Identities = 35/91 (38%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
Frame = +2
Query: 251 RVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXI-GEKSLXTKXLXDALMS 427
++AL QT V LK E KI+ T GDR D+PL + G + L D +++
Sbjct: 9 QLALAQTENVARLLKERGVETSIKIIK--TSGDRFTDRPLHAVSGGVGAFVRELDDVMLA 66
Query: 428 KNVDFVVHSLKDLPTTLPDGLVIGAVFKXXT 520
+D VHS+KD+PT P+GL AV K T
Sbjct: 67 GEIDIAVHSMKDMPTIRPEGLPTVAVLKRDT 97
>UniRef50_Q8RFP5 Cluster: Porphobilinogen deaminase; n=3;
Fusobacterium nucleatum|Rep: Porphobilinogen deaminase -
Fusobacterium nucleatum subsp. nucleatum
Length = 298
Score = 59.7 bits (138), Expect = 4e-08
Identities = 32/86 (37%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Frame = +2
Query: 254 VALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPX--IGEKSLXTKXLXDALMS 427
+AL Q N V D L+ NYP F+I + T GD+ L I KS TK + L+
Sbjct: 14 LALAQANLVKDRLQGNYPNLSFEIKEIVTSGDKDLKSNWENSDISLKSFFTKEIEQELLD 73
Query: 428 KNVDFVVHSLKDLPTTLPDGLVIGAV 505
+D VHS+KD+P L+ GA+
Sbjct: 74 GEIDIAVHSMKDMPAVSAKSLICGAI 99
>UniRef50_A5CDH4 Cluster: Porphobilinogen deaminase; n=1; Orientia
tsutsugamushi Boryong|Rep: Porphobilinogen deaminase -
Orientia tsutsugamushi (strain Boryong) (Rickettsia
tsutsugamushi)
Length = 298
Score = 59.3 bits (137), Expect = 6e-08
Identities = 32/87 (36%), Positives = 48/87 (55%)
Frame = +2
Query: 251 RVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSK 430
R+AL+Q V+ + I+ + T GD + ++ L IG K L K + AL++
Sbjct: 11 RLALIQAQAVVQKINDLLGLNAI-IIPIKTTGDLIQNKNLYDIGGKGLFLKEIEYALLNN 69
Query: 431 NVDFVVHSLKDLPTTLPDGLVIGAVFK 511
+D VHSLKD+P LPDGL + AV +
Sbjct: 70 TIDIAVHSLKDVPAYLPDGLQLAAVLE 96
>UniRef50_Q8EY46 Cluster: Porphobilinogen deaminase; n=4;
Leptospira|Rep: Porphobilinogen deaminase - Leptospira
interrogans
Length = 547
Score = 58.8 bits (136), Expect = 7e-08
Identities = 34/100 (34%), Positives = 55/100 (55%), Gaps = 2/100 (2%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
++ +A +QT V+ +LK+ +PE + ++ GD+ L PL +G K + T+ L L
Sbjct: 15 RKSALAKLQTYLVLGALKKKFPEIQVELFFREASGDQDLQTPLWKMGTKGVFTQDLTADL 74
Query: 422 MSKNVDFVVHSLKDLPTT-LPDGLVIGAVFKXXTL-VMLW 535
+ K VD V+HS KDL PD +IG + + V+LW
Sbjct: 75 VEKKVDIVIHSWKDLDLEGHPDTTIIGVLDRADQRDVLLW 114
>UniRef50_Q8TXC8 Cluster: Probable porphobilinogen deaminase; n=2;
Methanopyrus kandleri|Rep: Probable porphobilinogen
deaminase - Methanopyrus kandleri
Length = 298
Score = 58.4 bits (135), Expect = 1e-07
Identities = 31/89 (34%), Positives = 51/89 (57%), Gaps = 1/89 (1%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYP-EKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDA 418
+ R+A++QT VI+ L+R P + E +IV + GD V D+PL +GEK + K +
Sbjct: 10 RSSRLAIIQTREVIELLERESPRDVEVEIVKTKSRGDVVRDRPLHKLGEKGVFVKEVDRL 69
Query: 419 LMSKNVDFVVHSLKDLPTTLPDGLVIGAV 505
++ D VHS KD+P+ + + + AV
Sbjct: 70 VLEGKADIAVHSAKDVPSVVDYPVDVAAV 98
>UniRef50_Q1AUK3 Cluster: Porphobilinogen deaminase; n=1;
Rubrobacter xylanophilus DSM 9941|Rep: Porphobilinogen
deaminase - Rubrobacter xylanophilus (strain DSM 9941 /
NBRC 16129)
Length = 305
Score = 58.0 bits (134), Expect = 1e-07
Identities = 25/56 (44%), Positives = 38/56 (67%)
Frame = +2
Query: 338 TLGDRVLDQPLPXIGEKSLXTKXLXDALMSKNVDFVVHSLKDLPTTLPDGLVIGAV 505
T DR D PL I ++ + T+ L +AL++ VD VHS+KD+PT +P+G+V+ AV
Sbjct: 40 TTSDRRPDDPLSVIDQRDVFTRQLDEALLAGEVDLAVHSMKDVPTEVPEGIVLAAV 95
>UniRef50_Q0BX92 Cluster: Porphobilinogen deaminase; n=1; Hyphomonas
neptunium ATCC 15444|Rep: Porphobilinogen deaminase -
Hyphomonas neptunium (strain ATCC 15444)
Length = 321
Score = 58.0 bits (134), Expect = 1e-07
Identities = 31/84 (36%), Positives = 47/84 (55%), Gaps = 1/84 (1%)
Frame = +2
Query: 254 VALVQTNFVIDSLKR-NYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSK 430
+AL Q + + D ++ + + +IV TT GD++ + L G K L T+ L DAL
Sbjct: 22 LALAQAHQIADGIRAASAGAYDCEIVAFTTTGDKLTTERLINSGGKGLFTRELDDALSRG 81
Query: 431 NVDFVVHSLKDLPTTLPDGLVIGA 502
+D VHSLKD+P+ LP G + A
Sbjct: 82 ELDLAVHSLKDVPSVLPPGQIFAA 105
>UniRef50_A4BYX0 Cluster: Porphobilinogen deaminase HemC; n=11;
Bacteroidetes|Rep: Porphobilinogen deaminase HemC -
Polaribacter irgensii 23-P
Length = 531
Score = 57.6 bits (133), Expect = 2e-07
Identities = 30/66 (45%), Positives = 39/66 (59%)
Frame = +2
Query: 314 EFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKNVDFVVHSLKDLPTTLPDGLV 493
E +V + + GD LD PL +G + TK L AL+ +D VHSLKD+PT LP G+V
Sbjct: 32 ESVLVPIKSSGDINLDTPLYEMGITGIFTKSLDIALLEGKIDIAVHSLKDVPTALPKGIV 91
Query: 494 IGAVFK 511
AV K
Sbjct: 92 QAAVLK 97
>UniRef50_Q2NEP4 Cluster: HemC; n=1; Methanosphaera stadtmanae DSM
3091|Rep: HemC - Methanosphaera stadtmanae (strain DSM
3091)
Length = 290
Score = 57.6 bits (133), Expect = 2e-07
Identities = 34/86 (39%), Positives = 50/86 (58%), Gaps = 1/86 (1%)
Frame = +2
Query: 251 RVALVQTNFVIDSLKRNYPEK-EFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMS 427
++A QT V+ +L+ E+ E KI+ T GD++ + L I K + TK L AL+
Sbjct: 9 KLATTQTKTVVKALEEITGEEIETKIIKTT--GDKIKNSQLYNIDAKGIFTKELDTALID 66
Query: 428 KNVDFVVHSLKDLPTTLPDGLVIGAV 505
++DF VHS KDLP+ L D L I A+
Sbjct: 67 GSIDFAVHSFKDLPSELNDQLTITAI 92
>UniRef50_Q4PFH9 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 770
Score = 57.2 bits (132), Expect = 2e-07
Identities = 32/67 (47%), Positives = 41/67 (61%), Gaps = 2/67 (2%)
Frame = +2
Query: 317 FKIVTMTTLGDRVLDQPLPXIGE--KSLXTKXLXDALMSKNVDFVVHSLKDLPTTLPDGL 490
F I +M+T GD+ L PL IG K++ TK L AL VD +VH LKD+PT LP GL
Sbjct: 251 FPITSMSTAGDQNLRSPLYVIGGEGKAIWTKELEVALEQGAVDAIVHCLKDVPTALPQGL 310
Query: 491 VIGAVFK 511
+ AV +
Sbjct: 311 ELAAVLE 317
>UniRef50_Q9HMY5 Cluster: Probable porphobilinogen deaminase; n=1;
Halobacterium salinarum|Rep: Probable porphobilinogen
deaminase - Halobacterium salinarium (Halobacterium
halobium)
Length = 396
Score = 57.2 bits (132), Expect = 2e-07
Identities = 31/84 (36%), Positives = 48/84 (57%)
Frame = +2
Query: 254 VALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKN 433
+AL Q V+D+L+ + E +V + T GDRV D + +G+ + L +M
Sbjct: 15 LALRQAGEVVDTLEDRRHDVE--LVEVETEGDRVTDALISDLGKTGAFVRALDQEVMEGT 72
Query: 434 VDFVVHSLKDLPTTLPDGLVIGAV 505
VD VHS+KD+PT +P+ LV+ AV
Sbjct: 73 VDAAVHSMKDVPTEVPEDLVVAAV 96
>UniRef50_Q11XT5 Cluster: Porphobilinogen deaminase; n=6;
Bacteria|Rep: Porphobilinogen deaminase - Cytophaga
hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Length = 312
Score = 57.2 bits (132), Expect = 2e-07
Identities = 34/85 (40%), Positives = 47/85 (55%)
Frame = +2
Query: 251 RVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSK 430
++AL Q V L+ E + IV + T GD++LDQ L IG K L T+ L + L +
Sbjct: 13 KLALWQAEHVAACLQTKGLEPQ--IVIIDTTGDKILDQSLSKIGSKGLFTEELEEQLHAG 70
Query: 431 NVDFVVHSLKDLPTTLPDGLVIGAV 505
+D VHS KDL T L G+ I A+
Sbjct: 71 TIDIAVHSAKDLQTHLKGGMYILAI 95
>UniRef50_Q3W4S6 Cluster: Porphobilinogen deaminase; n=1; Frankia
sp. EAN1pec|Rep: Porphobilinogen deaminase - Frankia sp.
EAN1pec
Length = 354
Score = 56.4 bits (130), Expect = 4e-07
Identities = 35/92 (38%), Positives = 50/92 (54%), Gaps = 2/92 (2%)
Frame = +2
Query: 236 RLQEERVALV--QTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXL 409
RL R AL Q+ V ++L+ + ++V + T GD+ + IG + L
Sbjct: 21 RLGTRRSALARAQSEKVAETLRTRL-SRPVELVPIVTAGDQS-QVAISQIGGTGVFVSAL 78
Query: 410 XDALMSKNVDFVVHSLKDLPTTLPDGLVIGAV 505
DAL++ +D VHSLKDLPT PDGLV+ AV
Sbjct: 79 RDALLAGEIDLAVHSLKDLPTATPDGLVLAAV 110
>UniRef50_Q83A37 Cluster: Porphobilinogen deaminase; n=3; Coxiella
burnetii|Rep: Porphobilinogen deaminase - Coxiella
burnetii
Length = 307
Score = 56.4 bits (130), Expect = 4e-07
Identities = 29/86 (33%), Positives = 47/86 (54%)
Frame = +2
Query: 254 VALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKN 433
+AL Q FV ++ ++P +I+ TT GDR+ + L G K L K L AL++++
Sbjct: 16 LALWQAEFVKQQIENSHPHLACQILGCTTQGDRLTTEKLVDSGGKDLFVKDLQKALLNRD 75
Query: 434 VDFVVHSLKDLPTTLPDGLVIGAVFK 511
D VHS+KD+ L++GA +
Sbjct: 76 ADIAVHSIKDMSACDGPELMVGAFIR 101
>UniRef50_UPI0000DAE5D1 Cluster: hypothetical protein
Rgryl_01000734; n=1; Rickettsiella grylli|Rep:
hypothetical protein Rgryl_01000734 - Rickettsiella
grylli
Length = 311
Score = 56.0 bits (129), Expect = 5e-07
Identities = 33/86 (38%), Positives = 45/86 (52%)
Frame = +2
Query: 254 VALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKN 433
+A Q + + L++ +P + ++ T GDR L G K L K L AL+
Sbjct: 16 LAYWQATSIKNQLEKIFPFLKITLLPFVTEGDRP-SHSLNQWGGKGLFVKELEAALLHGQ 74
Query: 434 VDFVVHSLKDLPTTLPDGLVIGAVFK 511
D VHSLKDLP TL GLV+GA+ K
Sbjct: 75 ADIAVHSLKDLPMTLEKGLVLGAICK 100
>UniRef50_A3H5P0 Cluster: Porphobilinogen deaminase; n=1; Caldivirga
maquilingensis IC-167|Rep: Porphobilinogen deaminase -
Caldivirga maquilingensis IC-167
Length = 305
Score = 56.0 bits (129), Expect = 5e-07
Identities = 27/81 (33%), Positives = 45/81 (55%)
Frame = +2
Query: 254 VALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKN 433
++L QT V+D + + EFK++ + T GD L +PL IG K + + + A++
Sbjct: 12 LSLKQTKIVMDRILEFNKDVEFKLIIVKTTGDVDLSKPLYEIGVKGIFEREVNQAVLRGE 71
Query: 434 VDFVVHSLKDLPTTLPDGLVI 496
D VHSLKD+P + + L +
Sbjct: 72 ADVAVHSLKDMPAQISNDLTL 92
>UniRef50_Q9F7M2 Cluster: Predicted porphobilinogen deaminase; n=2;
Bacteria|Rep: Predicted porphobilinogen deaminase -
Gamma-proteobacterium EBAC31A08
Length = 303
Score = 55.6 bits (128), Expect = 7e-07
Identities = 32/89 (35%), Positives = 46/89 (51%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
++ +A+ Q FV D L + ++V MT+ GD+ D+PL IG K L L +L
Sbjct: 8 RQSELAMYQAKFVADELLAKINNIKVELVPMTSEGDQT-DKPLHEIGGKGLFISTLESSL 66
Query: 422 MSKNVDFVVHSLKDLPTTLPDGLVIGAVF 508
+ D VHSLKD+P L I +VF
Sbjct: 67 EADEADIAVHSLKDVPAKLDPKFKIISVF 95
>UniRef50_Q2JFS0 Cluster: Porphobilinogen deaminase; n=2;
Frankia|Rep: Porphobilinogen deaminase - Frankia sp.
(strain CcI3)
Length = 395
Score = 55.2 bits (127), Expect = 9e-07
Identities = 33/84 (39%), Positives = 46/84 (54%)
Frame = +2
Query: 254 VALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKN 433
+AL Q+ V +L+ ++V + T GDR + + IG + L DAL+S
Sbjct: 51 LALAQSGTVAATLRARVG-CAVELVPIVTAGDRSSGE-ISQIGGTGVFVSALRDALLSGE 108
Query: 434 VDFVVHSLKDLPTTLPDGLVIGAV 505
+D VHSLKDLPT P GLV+ AV
Sbjct: 109 IDLAVHSLKDLPTATPPGLVLAAV 132
>UniRef50_Q2GJX6 Cluster: Porphobilinogen deaminase; n=11;
Rickettsiales|Rep: Porphobilinogen deaminase - Anaplasma
phagocytophilum (strain HZ)
Length = 304
Score = 55.2 bits (127), Expect = 9e-07
Identities = 29/84 (34%), Positives = 44/84 (52%)
Frame = +2
Query: 254 VALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKN 433
+A+ Q V +++ NY E +I+T+ T GD PL IG K L K + +AL+
Sbjct: 16 LAMQQARIVKTAIETNYAELSTRIITIKTSGDMNTHVPLYDIGGKGLFIKEIEEALLDNI 75
Query: 434 VDFVVHSLKDLPTTLPDGLVIGAV 505
+D VHS KD+P + L I +
Sbjct: 76 IDVAVHSAKDVPGIYSEDLDIPCI 99
>UniRef50_O29026 Cluster: Probable porphobilinogen deaminase; n=1;
Archaeoglobus fulgidus|Rep: Probable porphobilinogen
deaminase - Archaeoglobus fulgidus
Length = 289
Score = 55.2 bits (127), Expect = 9e-07
Identities = 34/87 (39%), Positives = 46/87 (52%)
Frame = +2
Query: 251 RVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSK 430
++AL QTN V + LK Y E E +IV T GD + D+PL + L AL
Sbjct: 11 KLALAQTNKVAERLKERY-EVEIRIVK--TAGDIMKDKPLYEFKGMGAFVRALDTALAEG 67
Query: 431 NVDFVVHSLKDLPTTLPDGLVIGAVFK 511
VD VHS KD+P+ +G V+ AV +
Sbjct: 68 KVDVAVHSFKDVPSQRVEGTVVAAVIE 94
>UniRef50_A5K0J5 Cluster: Porphobilinogen deaminase, putative; n=1;
Plasmodium vivax|Rep: Porphobilinogen deaminase,
putative - Plasmodium vivax
Length = 341
Score = 54.0 bits (124), Expect = 2e-06
Identities = 24/61 (39%), Positives = 36/61 (59%)
Frame = +2
Query: 341 LGDRVLDQPLPXIGEKSLXTKXLXDALMSKNVDFVVHSLKDLPTTLPDGLVIGAVFKXXT 520
+GD +LD+ + G K + TK L + L+ KNV VHSLKD+P LP+ + + K T
Sbjct: 1 MGDHILDKKVGLFGGKGIFTKELDEQLIKKNVHICVHSLKDVPMELPEHVQLSCFLKRDT 60
Query: 521 L 523
+
Sbjct: 61 I 61
>UniRef50_UPI00006CBE06 Cluster: porphobilinogen deaminase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
porphobilinogen deaminase family protein - Tetrahymena
thermophila SB210
Length = 362
Score = 52.8 bits (121), Expect = 5e-06
Identities = 37/94 (39%), Positives = 52/94 (55%), Gaps = 8/94 (8%)
Frame = +2
Query: 248 ERVALVQTNFVIDSLKRNYPEK----EFKI-VT---MTTLGDRVLDQPLPXIGEKSLXTK 403
+ + L + NF + + N P K +FKI +T T GD+ L PL +G + TK
Sbjct: 46 KELGLTKENFEVVPIS-NAPGKNCTLKFKINITNKQFTNKGDQNLKDPLYVMGGVGVFTK 104
Query: 404 XLXDALMSKNVDFVVHSLKDLPTTLPDGLVIGAV 505
+ L++KN D VHSLKDLPT + + L IGAV
Sbjct: 105 IVEVELLNKNGDIAVHSLKDLPTIIDERLFIGAV 138
>UniRef50_Q6MHU0 Cluster: Hydroxymethylbilane synthase; n=1;
Bdellovibrio bacteriovorus|Rep: Hydroxymethylbilane
synthase - Bdellovibrio bacteriovorus
Length = 502
Score = 52.8 bits (121), Expect = 5e-06
Identities = 32/83 (38%), Positives = 41/83 (49%)
Frame = +2
Query: 254 VALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKN 433
+A +Q V D+LK P+ E +LGD+ L PL I EK + T+ L+
Sbjct: 12 LARLQAYMVGDALKEKNPQIEIDYRFRESLGDKNLTDPLWKIPEKGVFTEDFFGELLRDE 71
Query: 434 VDFVVHSLKDLPTTLPDGLVIGA 502
D VVHS KDLPT VI A
Sbjct: 72 TDLVVHSWKDLPTEHKSETVIAA 94
>UniRef50_A1DGB8 Cluster: Porphobilinogen deaminase; n=1;
Neosartorya fischeri NRRL 181|Rep: Porphobilinogen
deaminase - Neosartorya fischeri (strain ATCC 1020 / DSM
3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC
1020 / DSM 3700 / NRRL 181))
Length = 363
Score = 52.8 bits (121), Expect = 5e-06
Identities = 35/97 (36%), Positives = 51/97 (52%), Gaps = 9/97 (9%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNY-PEKEFKIVTMTTLGDRVLDQPLPXIGE--------KSL 394
++ +ALVQT +V L + P F+I T + +GD P + + KSL
Sbjct: 28 RKSELALVQTRWVTSKLGQTLDPSPTFQIATGSAVGDADKQAPFAVLSKLTGGSDIGKSL 87
Query: 395 XTKXLXDALMSKNVDFVVHSLKDLPTTLPDGLVIGAV 505
T L L++ V +VHSLKD+PTTLP ++GAV
Sbjct: 88 WTNELELDLVAGKVHCLVHSLKDMPTTLPPHCLLGAV 124
>UniRef50_Q2FTK7 Cluster: Porphobilinogen deaminase; n=1;
Methanospirillum hungatei JF-1|Rep: Porphobilinogen
deaminase - Methanospirillum hungatei (strain JF-1 / DSM
864)
Length = 295
Score = 52.8 bits (121), Expect = 5e-06
Identities = 24/62 (38%), Positives = 36/62 (58%)
Frame = +2
Query: 320 KIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKNVDFVVHSLKDLPTTLPDGLVIG 499
++V ++T GD PL IG + + + L DAL+ +D VHS+KD+P P GLV
Sbjct: 32 ELVFISTAGDEQTGVPLHEIGGQGVFVRALDDALVQNKIDLAVHSMKDIPAERPYGLVTS 91
Query: 500 AV 505
A+
Sbjct: 92 AI 93
>UniRef50_Q6MEK3 Cluster: Putative Porphobilinogen deaminase; n=1;
Candidatus Protochlamydia amoebophila UWE25|Rep:
Putative Porphobilinogen deaminase - Protochlamydia
amoebophila (strain UWE25)
Length = 233
Score = 52.4 bits (120), Expect = 6e-06
Identities = 25/75 (33%), Positives = 39/75 (52%)
Frame = +2
Query: 266 QTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKNVDFV 445
Q ++ +L+ YP EF I T+GD L + + + TK + +A++ K
Sbjct: 31 QVQEILKALRSFYPSIEFTISYFDTIGDLDQKTSLRDLDKTNFFTKEIDEAILQKKCQIG 90
Query: 446 VHSLKDLPTTLPDGL 490
+HS KDLP +PDGL
Sbjct: 91 IHSAKDLPDPIPDGL 105
>UniRef50_Q5HBG1 Cluster: Porphobilinogen deaminase; n=2; Ehrlichia
ruminantium|Rep: Porphobilinogen deaminase - Ehrlichia
ruminantium (strain Welgevonden)
Length = 299
Score = 52.4 bits (120), Expect = 6e-06
Identities = 31/86 (36%), Positives = 44/86 (51%)
Frame = +2
Query: 254 VALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKN 433
+A+ Q V L +P+ +IV + T GD L IG K L K L +AL++
Sbjct: 15 LAIAQAMEVKKLLYNYFPDINVQIVHIVTSGDINDKISLSEIGGKGLFLKELEEALLTGT 74
Query: 434 VDFVVHSLKDLPTTLPDGLVIGAVFK 511
+D VHS+KD+P D LVI + K
Sbjct: 75 IDLAVHSMKDVPAFYCDSLVIPCILK 100
>UniRef50_Q1GP41 Cluster: Porphobilinogen deaminase; n=7;
Sphingomonadales|Rep: Porphobilinogen deaminase -
Sphingopyxis alaskensis (Sphingomonas alaskensis)
Length = 315
Score = 52.0 bits (119), Expect = 8e-06
Identities = 26/64 (40%), Positives = 38/64 (59%)
Frame = +2
Query: 320 KIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKNVDFVVHSLKDLPTTLPDGLVIG 499
+IV MT GDR+ D+ L +G K+L T+ L AL + +D VHSLKD+ T +G
Sbjct: 44 EIVPMTATGDRIQDRALAEVGGKALWTRELDAALDAGTIDVAVHSLKDVETLRDARFFLG 103
Query: 500 AVFK 511
A+ +
Sbjct: 104 AMLE 107
>UniRef50_A3ZKX4 Cluster: Porphobilinogen deaminase; n=1;
Blastopirellula marina DSM 3645|Rep: Porphobilinogen
deaminase - Blastopirellula marina DSM 3645
Length = 308
Score = 52.0 bits (119), Expect = 8e-06
Identities = 33/85 (38%), Positives = 46/85 (54%)
Frame = +2
Query: 251 RVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSK 430
++A Q N+V D L+ + E I+ + T GD V PL IG + + T + AL+
Sbjct: 12 QLAQWQANWVADQLRAVGTDVE--IIHIATQGD-VTQGPLDLIGGRGVFTTEIQAALLDN 68
Query: 431 NVDFVVHSLKDLPTTLPDGLVIGAV 505
+D VHSLKDLPT GL + AV
Sbjct: 69 RIDVAVHSLKDLPTEAVVGLRLAAV 93
>UniRef50_Q5NL83 Cluster: Porphobilinogen deaminase; n=1; Zymomonas
mobilis|Rep: Porphobilinogen deaminase - Zymomonas
mobilis
Length = 308
Score = 51.6 bits (118), Expect = 1e-05
Identities = 32/86 (37%), Positives = 46/86 (53%), Gaps = 2/86 (2%)
Frame = +2
Query: 254 VALVQTNFVIDSL--KRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMS 427
+AL+Q V +L ++ E IV + T GD+ Q L IG K+L TK L AL +
Sbjct: 14 LALIQARSVASALCAAHSWSEDAVVIVPIRTSGDKNRHQALADIGGKALWTKELDIALTT 73
Query: 428 KNVDFVVHSLKDLPTTLPDGLVIGAV 505
+D VHS+KD+ T P + I A+
Sbjct: 74 GQIDAAVHSMKDVETFRPSHISIAAM 99
>UniRef50_Q6L2G8 Cluster: Probable porphobilinogen deaminase; n=2;
Thermoplasmatales|Rep: Probable porphobilinogen
deaminase - Picrophilus torridus
Length = 282
Score = 51.6 bits (118), Expect = 1e-05
Identities = 31/90 (34%), Positives = 44/90 (48%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
+ ++A++Q V D L E E K T+ GD LD PL IG + L +
Sbjct: 8 RSSKLAMIQAMMVKDRLDSLGIETEVK--GFTSKGDINLDSPLYSIGGTGVFVDDLNRMI 65
Query: 422 MSKNVDFVVHSLKDLPTTLPDGLVIGAVFK 511
+ +D VHS KD+P+ + D L I AV K
Sbjct: 66 LKNEIDIAVHSAKDIPSFIDDSLEISAVLK 95
>UniRef50_Q2GE22 Cluster: Putative porphobilinogen deaminase; n=1;
Neorickettsia sennetsu str. Miyayama|Rep: Putative
porphobilinogen deaminase - Neorickettsia sennetsu
(strain Miyayama)
Length = 286
Score = 51.2 bits (117), Expect = 1e-05
Identities = 30/86 (34%), Positives = 45/86 (52%)
Frame = +2
Query: 254 VALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKN 433
+AL+Q V +L + +V + T GD V D PL +G K+L K L + L++
Sbjct: 13 LALIQARLVERALAPYCARTD--LVEVKTSGDIVSDVPLTEVGGKALFLKELEEKLLTGE 70
Query: 434 VDFVVHSLKDLPTTLPDGLVIGAVFK 511
+D VHS+KD+P D L + V K
Sbjct: 71 IDIAVHSMKDVPAFYHDDLEVVPVLK 96
>UniRef50_Q93A65 Cluster: Porphobilinogen deaminase; n=1; uncultured
bacterium|Rep: Porphobilinogen deaminase - uncultured
bacterium
Length = 299
Score = 51.2 bits (117), Expect = 1e-05
Identities = 32/85 (37%), Positives = 45/85 (52%)
Frame = +2
Query: 251 RVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSK 430
R+AL Q +V L + E E +V + T GDR +P + + TK + +A++
Sbjct: 12 RLALWQAEWVAKQLVQQGAEVE--LVVVETQGDRE-KRPFAQMQGQGFFTKAVQEAVLEG 68
Query: 431 NVDFVVHSLKDLPTTLPDGLVIGAV 505
DF VHS KDLP+ P GL I AV
Sbjct: 69 RADFAVHSYKDLPSARPAGLEIAAV 93
>UniRef50_Q5KKQ0 Cluster: Hydroxymethylbilane synthase, putative;
n=2; Filobasidiella neoformans|Rep: Hydroxymethylbilane
synthase, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 481
Score = 51.2 bits (117), Expect = 1e-05
Identities = 31/72 (43%), Positives = 40/72 (55%), Gaps = 7/72 (9%)
Frame = +2
Query: 317 FKIVTMTTLGDRVLDQPLPXIGE-------KSLXTKXLXDALMSKNVDFVVHSLKDLPTT 475
F I +MTT+GDR PL + KSL T L L++ + D +VHSLKD+PT
Sbjct: 88 FSIESMTTVGDRNQTTPLHLLSPYSSTQPAKSLWTDELEARLINGHFDMLVHSLKDVPTV 147
Query: 476 LPDGLVIGAVFK 511
L DG IG + K
Sbjct: 148 LKDGCEIGCMAK 159
>UniRef50_Q5UY52 Cluster: Porphobilinogen deaminase; n=3;
Halobacteriaceae|Rep: Porphobilinogen deaminase -
Haloarcula marismortui (Halobacterium marismortui)
Length = 389
Score = 50.4 bits (115), Expect = 3e-05
Identities = 28/84 (33%), Positives = 46/84 (54%)
Frame = +2
Query: 254 VALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKN 433
+AL Q V DSL E +V + T GD++ D+ + +G+ + L + ++
Sbjct: 17 LALRQAATVRDSLSSRRLAVE--LVEVETTGDQIRDELIHRLGKTGAFVRSLDEKVLDGE 74
Query: 434 VDFVVHSLKDLPTTLPDGLVIGAV 505
+D VHS+KD+PT P+ LV+ AV
Sbjct: 75 LDAAVHSMKDMPTERPERLVVAAV 98
>UniRef50_A2Q9P7 Cluster: Catalytic activity: 4
porphobilinogen+H(2)O<=>hydroxymethylbilane+4 NH; n=1;
Aspergillus niger|Rep: Catalytic activity: 4
porphobilinogen+H(2)O<=>hydroxymethylbilane+4 NH -
Aspergillus niger
Length = 346
Score = 49.6 bits (113), Expect = 5e-05
Identities = 28/93 (30%), Positives = 45/93 (48%), Gaps = 5/93 (5%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPL-----PXIGEKSLXTKX 406
+ ++ALVQ V L +P +F T+ GD P P K++ T+
Sbjct: 17 RNSKLALVQAEHVSKELTSAHPGVQFPWQTVVVRGDADKSSPFLKFAGPSDAAKNIWTEE 76
Query: 407 LXDALMSKNVDFVVHSLKDLPTTLPDGLVIGAV 505
+ L + +D +VH LKD+PT LP+ +GA+
Sbjct: 77 METKLCAGELDLLVHCLKDMPTRLPETCTLGAI 109
>UniRef50_UPI00015BAF19 Cluster: hydroxymethylbilane synthase; n=1;
Ignicoccus hospitalis KIN4/I|Rep: hydroxymethylbilane
synthase - Ignicoccus hospitalis KIN4/I
Length = 304
Score = 49.2 bits (112), Expect = 6e-05
Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
Frame = +2
Query: 251 RVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLD--QPLPXIGEKSLXTKXLXDALM 424
+++L Q + L + +P+ E++++T+ T GD+ + L G L K + A++
Sbjct: 11 KLSLKQVSMFTSYLLKFFPDLEYEVITVKTTGDKANAPFEELAKRGLTGLFEKEVNKAVL 70
Query: 425 SKNVDFVVHSLKDLPTTLPDGLVIGA 502
D VHSLKDLPT L L I A
Sbjct: 71 EGKADVAVHSLKDLPTELDPRLEIAA 96
>UniRef50_A0DD68 Cluster: Chromosome undetermined scaffold_46, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_46,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 306
Score = 48.8 bits (111), Expect = 8e-05
Identities = 31/87 (35%), Positives = 47/87 (54%), Gaps = 1/87 (1%)
Frame = +2
Query: 254 VALVQTNFVIDSLKRNYPEKEFKIVTMTT-LGDRVLDQPLPXIGEKSLXTKXLXDALMSK 430
+A+ QTN+VI LK+ E +I+ ++ +GD L PL + + TK + L+ +
Sbjct: 14 LAMAQTNYVISELKQ-----ECEIIKVSNEVGDVNLQDPLYQMPTVGVFTKQVEQYLLEQ 68
Query: 431 NVDFVVHSLKDLPTTLPDGLVIGAVFK 511
D VHSLKDLPT + L + A K
Sbjct: 69 KADVAVHSLKDLPTIIDAQLHLAAYTK 95
>UniRef50_Q4FNV7 Cluster: Hydroxymethylbilane synthase; n=2;
Candidatus Pelagibacter ubique|Rep: Hydroxymethylbilane
synthase - Pelagibacter ubique
Length = 307
Score = 48.0 bits (109), Expect = 1e-04
Identities = 23/66 (34%), Positives = 39/66 (59%)
Frame = +2
Query: 296 RNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKNVDFVVHSLKDLPTT 475
+++ +E I + T GD+V D+ L +G K L +K + L+ K +D VH+LKD+P+
Sbjct: 32 KDFGIEEVIIKEIVTKGDQVQDKRLSEVGGKGLFSKTIEVELLEKKIDIAVHALKDMPSE 91
Query: 476 LPDGLV 493
GL+
Sbjct: 92 ETRGLL 97
>UniRef50_A7D1I3 Cluster: Porphobilinogen deaminase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Porphobilinogen deaminase
- Halorubrum lacusprofundi ATCC 49239
Length = 415
Score = 46.8 bits (106), Expect = 3e-04
Identities = 27/84 (32%), Positives = 44/84 (52%)
Frame = +2
Query: 254 VALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKN 433
+AL Q V D+L + E + V T GD++ D+ + +G+ + L + ++ +
Sbjct: 44 LALRQAGTVRDALSSRRRDVELRRVE--TRGDQIPDEMIHRLGKTGAFVRALDEEVLGGD 101
Query: 434 VDFVVHSLKDLPTTLPDGLVIGAV 505
D VHSLKD+PT D +VI V
Sbjct: 102 ADLAVHSLKDVPTEGMDDMVIAGV 125
>UniRef50_Q9Y9J0 Cluster: Probable porphobilinogen deaminase; n=1;
Aeropyrum pernix|Rep: Probable porphobilinogen deaminase
- Aeropyrum pernix
Length = 307
Score = 45.6 bits (103), Expect = 7e-04
Identities = 25/76 (32%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
Frame = +2
Query: 251 RVALVQTNFVIDSLKRNYP-EKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMS 427
R++L+Q ++ L R +++V + + GD D+PL IG + T+ + A+ S
Sbjct: 11 RLSLLQVEQALEELSRYAGVSMHWEVVRVKSAGDVWSDRPLESIGVVGVFTREVDRAVAS 70
Query: 428 KNVDFVVHSLKDLPTT 475
D VHSLKD+PT+
Sbjct: 71 GAADIAVHSLKDMPTS 86
>UniRef50_Q7UPN0 Cluster: Porphobilinogen deaminase; n=1; Pirellula
sp.|Rep: Porphobilinogen deaminase - Rhodopirellula
baltica
Length = 337
Score = 45.2 bits (102), Expect = 0.001
Identities = 30/88 (34%), Positives = 45/88 (51%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
+E +A+ Q V LK++ + E IV + + GD + +P+ + L TK + AL
Sbjct: 17 RESPLAMWQAEHVAKLLKKHGFQTE--IVPLVSKGDTDM-RPIDGTRQVGLFTKRIQQAL 73
Query: 422 MSKNVDFVVHSLKDLPTTLPDGLVIGAV 505
+ D VHSLKDLPT V+ AV
Sbjct: 74 VDDEADVAVHSLKDLPTEPDSRFVLAAV 101
>UniRef50_A0LRF1 Cluster: Porphobilinogen deaminase precursor; n=2;
Actinomycetales|Rep: Porphobilinogen deaminase precursor
- Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 331
Score = 44.4 bits (100), Expect = 0.002
Identities = 25/62 (40%), Positives = 32/62 (51%)
Frame = +2
Query: 320 KIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKNVDFVVHSLKDLPTTLPDGLVIG 499
+IV + + GDR D PL + L AL+ VD VVHS+KDLPT L I
Sbjct: 39 EIVGIQSTGDRHADVPLHEFAGSGVFVAELRAALLRGEVDVVVHSMKDLPTAEIPELAIA 98
Query: 500 AV 505
A+
Sbjct: 99 AI 100
>UniRef50_Q97B26 Cluster: Probable porphobilinogen deaminase; n=2;
Thermoplasma|Rep: Probable porphobilinogen deaminase -
Thermoplasma volcanium
Length = 297
Score = 44.0 bits (99), Expect = 0.002
Identities = 26/86 (30%), Positives = 43/86 (50%)
Frame = +2
Query: 254 VALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKN 433
+A+ Q N V SL+ + E IV + GD P+ IG+ + + L + ++
Sbjct: 12 LAVAQANMVASSLEAIGIDTE--IVKHRSAGDIDTKNPIYSIGKTGVFVQDLNNMILRGE 69
Query: 434 VDFVVHSLKDLPTTLPDGLVIGAVFK 511
+D VHS KD+P+ + + L I A K
Sbjct: 70 IDVAVHSAKDIPSEIENRLTIAATLK 95
>UniRef50_UPI000155526F Cluster: PREDICTED: similar to
hydroxymethylbilane synthase; n=1; Ornithorhynchus
anatinus|Rep: PREDICTED: similar to hydroxymethylbilane
synthase - Ornithorhynchus anatinus
Length = 218
Score = 43.6 bits (98), Expect = 0.003
Identities = 20/26 (76%), Positives = 20/26 (76%)
Frame = +2
Query: 434 VDFVVHSLKDLPTTLPDGLVIGAVFK 511
VD VVHSLKDLPT LP G IGAV K
Sbjct: 90 VDLVVHSLKDLPTVLPPGFTIGAVCK 115
>UniRef50_Q6AB05 Cluster: Porphobilinogen deaminase; n=17;
Actinomycetales|Rep: Porphobilinogen deaminase -
Propionibacterium acnes
Length = 334
Score = 43.6 bits (98), Expect = 0.003
Identities = 25/64 (39%), Positives = 32/64 (50%)
Frame = +2
Query: 314 EFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKNVDFVVHSLKDLPTTLPDGLV 493
+ + T+TT GD L +G + + AL+ D VHS KDLPT P GL
Sbjct: 31 DVNLTTITTHGD-TSTASLAAMGGIGVFASAIRAALLEGEADIAVHSFKDLPTGRPLGLA 89
Query: 494 IGAV 505
IGAV
Sbjct: 90 IGAV 93
>UniRef50_A5CNI4 Cluster: HemC protein; n=2; Actinobacteria
(class)|Rep: HemC protein - Clavibacter michiganensis
subsp. michiganensis (strain NCPPB 382)
Length = 328
Score = 43.2 bits (97), Expect = 0.004
Identities = 24/64 (37%), Positives = 35/64 (54%)
Frame = +2
Query: 314 EFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKNVDFVVHSLKDLPTTLPDGLV 493
E ++V +TT GD + L +G + L ++L+ D VVHSLKDLPT GL
Sbjct: 42 EVELVPVTTHGDTSRES-LSSLGGTGVFASALRESLLRGECDLVVHSLKDLPTAPYAGLT 100
Query: 494 IGAV 505
+ +V
Sbjct: 101 VASV 104
>UniRef50_A4YD92 Cluster: Porphobilinogen deaminase; n=1;
Metallosphaera sedula DSM 5348|Rep: Porphobilinogen
deaminase - Metallosphaera sedula DSM 5348
Length = 290
Score = 42.7 bits (96), Expect = 0.005
Identities = 28/87 (32%), Positives = 45/87 (51%)
Frame = +2
Query: 251 RVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSK 430
+++L Q V L+ E EF + + T D ++PL IG K + K + +A++
Sbjct: 11 KLSLKQVEIVTTYLQAKGYETEF--IEIKTKADLFGNKPLHEIG-KGVFEKEVNEAVLQG 67
Query: 431 NVDFVVHSLKDLPTTLPDGLVIGAVFK 511
D VHS+KD+ + LP GL + A K
Sbjct: 68 RADIAVHSMKDMSSELPPGLELLATPK 94
>UniRef50_Q82P95 Cluster: Porphobilinogen deaminase 2; n=3;
Streptomyces|Rep: Porphobilinogen deaminase 2 -
Streptomyces avermitilis
Length = 314
Score = 41.9 bits (94), Expect = 0.009
Identities = 27/92 (29%), Positives = 43/92 (46%), Gaps = 2/92 (2%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
++ +AL Q V L +P ++V + T GD+ + L + K TK + AL
Sbjct: 15 RDSPMALAQVARVRAELAALHPRTRTEVVAVKTTGDKWMGD-LSKVDGKGAFTKEVDAAL 73
Query: 422 MSKNVDFVVHSLKDLPT--TLPDGLVIGAVFK 511
++ D VH +KD+P LP G + A K
Sbjct: 74 LAGEADLAVHCVKDVPADRPLPAGTMFAAFLK 105
>UniRef50_Q8NT90 Cluster: Porphobilinogen deaminase; n=5;
Corynebacterium|Rep: Porphobilinogen deaminase -
Corynebacterium glutamicum (Brevibacterium flavum)
Length = 302
Score = 41.5 bits (93), Expect = 0.012
Identities = 30/74 (40%), Positives = 38/74 (51%)
Frame = +2
Query: 251 RVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSK 430
++A Q + D LK + E IVT T GD V P+ IG + T+ L D L S
Sbjct: 11 KLATTQAGTIRDQLKHYGRDAELHIVT--TPGD-VNMSPVERIGV-GVFTQALRDVLHSG 66
Query: 431 NVDFVVHSLKDLPT 472
D VHS+KDLPT
Sbjct: 67 ECDVAVHSMKDLPT 80
>UniRef50_Q8D2W2 Cluster: HemC protein; n=1; Wigglesworthia
glossinidia endosymbiont of Glossina brevipalpis|Rep:
HemC protein - Wigglesworthia glossinidia brevipalpis
Length = 291
Score = 41.1 bits (92), Expect = 0.016
Identities = 22/70 (31%), Positives = 34/70 (48%)
Frame = +2
Query: 302 YPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKNVDFVVHSLKDLPTTLP 481
+P+ K+V + T GD + EK L K L +L+ D VHS+KD ++
Sbjct: 14 HPKLNIKLVPILTTGDLINKIRNNITNEKGLFIKELEKSLLKYQSDIAVHSMKDFSSSFL 73
Query: 482 DGLVIGAVFK 511
D L + A+ K
Sbjct: 74 DSLGLAAICK 83
>UniRef50_A4XK06 Cluster: Porphobilinogen deaminase; n=1;
Caldicellulosiruptor saccharolyticus DSM 8903|Rep:
Porphobilinogen deaminase - Caldicellulosiruptor
saccharolyticus (strain ATCC 43494 / DSM 8903)
Length = 290
Score = 41.1 bits (92), Expect = 0.016
Identities = 25/88 (28%), Positives = 43/88 (48%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDAL 421
++ +++ +Q + V +K+ E + V + T GD + L + K + AL
Sbjct: 9 RDSKLSRIQVDIVARKIKQTLGI-ECEFVPIKTKGDIDKTKSLKDFKSPGVFVKEIELAL 67
Query: 422 MSKNVDFVVHSLKDLPTTLPDGLVIGAV 505
+S+ +D VHSLKDLP + I AV
Sbjct: 68 LSREIDLAVHSLKDLPCEMDSNFEIVAV 95
>UniRef50_Q5YP70 Cluster: Porphobilinogen deaminase; n=18;
Actinomycetales|Rep: Porphobilinogen deaminase -
Nocardia farcinica
Length = 346
Score = 39.5 bits (88), Expect = 0.048
Identities = 29/84 (34%), Positives = 41/84 (48%)
Frame = +2
Query: 254 VALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKN 433
+A+ Q V D+L + ++V + T GD D P+ IG + T L D L +
Sbjct: 19 LAMTQAGTVRDALIA--AGRPAELVVVKTPGDMSSD-PVQKIGV-GVFTSALRDELAAGT 74
Query: 434 VDFVVHSLKDLPTTLPDGLVIGAV 505
+D VHS KDLPT VI A+
Sbjct: 75 IDLAVHSYKDLPTAPDPRFVIAAI 98
>UniRef50_Q976H1 Cluster: Probable porphobilinogen deaminase; n=3;
Sulfolobus|Rep: Probable porphobilinogen deaminase -
Sulfolobus tokodaii
Length = 294
Score = 39.1 bits (87), Expect = 0.064
Identities = 25/85 (29%), Positives = 44/85 (51%)
Frame = +2
Query: 251 RVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSK 430
+++ +Q V + L + E EF + + T D ++PL +G K + K + A++
Sbjct: 11 KLSRIQVMMVENYLHKLGIETEF--IEIKTKADLFQNEPLSKLG-KGVFEKEVNQAVLDN 67
Query: 431 NVDFVVHSLKDLPTTLPDGLVIGAV 505
D VHS+KD+ T + + L I AV
Sbjct: 68 KADVAVHSMKDILTEISENLEIYAV 92
>UniRef50_Q9PK95 Cluster: Probable porphobilinogen deaminase; n=7;
Chlamydiaceae|Rep: Probable porphobilinogen deaminase -
Chlamydia muridarum
Length = 242
Score = 37.5 bits (83), Expect = 0.20
Identities = 20/72 (27%), Positives = 34/72 (47%)
Frame = +2
Query: 254 VALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKN 433
+A++Q + + L+ +P +++T TT GD PL + T + + S
Sbjct: 30 LAVLQAHECLRRLQTFFPRLWGQVITETTQGDLDQHTPLHSVENTGFFTDDIDFLVQSGK 89
Query: 434 VDFVVHSLKDLP 469
D +HS KDLP
Sbjct: 90 CDLAIHSAKDLP 101
>UniRef50_A6R1N6 Cluster: Predicted protein; n=1; Ajellomyces
capsulatus NAm1|Rep: Predicted protein - Ajellomyces
capsulatus NAm1
Length = 1212
Score = 35.1 bits (77), Expect = 1.0
Identities = 19/48 (39%), Positives = 26/48 (54%)
Frame = +2
Query: 218 ETKHSRRLQEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLD 361
E K S+ L++ R ALV N VID L+ +K + LGD +LD
Sbjct: 928 EAKESKTLEKRRKALVDKNVVIDKLESLQGDKAHIVRKRQELGDIILD 975
>UniRef50_A4YPB9 Cluster: Porphobilinogen deaminase; n=8;
Bradyrhizobiaceae|Rep: Porphobilinogen deaminase -
Bradyrhizobium sp. (strain ORS278)
Length = 325
Score = 34.7 bits (76), Expect = 1.4
Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 2/90 (2%)
Frame = +2
Query: 242 QEERVALVQTNFVIDSLKRNYPEKEFKIVTMTTLGDRVLDQPLPXIGEKS-LXTKXLXDA 418
++ +AL QT + L+ P + +IV T GD L G K + A
Sbjct: 9 RKSTMALAQTEEIARRLQAAIPSLDIEIVKFETTGDSDQTSKLLTHGGKGGAFVAEIRRA 68
Query: 419 LMSKNVDFVVHSLKDLP-TTLPDGLVIGAV 505
++ + +HSLKD+P GLVI A+
Sbjct: 69 MLDGKLHAAMHSLKDMPGNEETPGLVIAAL 98
>UniRef50_A6EWA1 Cluster: Putative uncharacterized protein; n=1;
Marinobacter algicola DG893|Rep: Putative
uncharacterized protein - Marinobacter algicola DG893
Length = 312
Score = 32.3 bits (70), Expect = 7.3
Identities = 18/53 (33%), Positives = 29/53 (54%)
Frame = +2
Query: 320 KIVTMTTLGDRVLDQPLPXIGEKSLXTKXLXDALMSKNVDFVVHSLKDLPTTL 478
++ +T + LDQ + IGE + + L L KN+D ++H L+D PT L
Sbjct: 250 RLEALTARNEGSLDQGMQGIGELAPAMRELRSTL--KNLDSLIHRLEDDPTGL 300
>UniRef50_UPI0000D9FBB5 Cluster: PREDICTED: similar to lethal (3)
02640 CG9165-PA; n=1; Macaca mulatta|Rep: PREDICTED:
similar to lethal (3) 02640 CG9165-PA - Macaca mulatta
Length = 105
Score = 31.9 bits (69), Expect = 9.7
Identities = 16/40 (40%), Positives = 20/40 (50%)
Frame = +2
Query: 383 EKSLXTKXLXDALMSKNVDFVVHSLKDLPTTLPDGLVIGA 502
E + T L L+ +VD VVHS KDLP G + A
Sbjct: 44 ETGVFTTFLRQKLLDGSVDLVVHSWKDLPLAEEAGTTVAA 83
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 426,429,102
Number of Sequences: 1657284
Number of extensions: 6979422
Number of successful extensions: 12815
Number of sequences better than 10.0: 127
Number of HSP's better than 10.0 without gapping: 12549
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 12796
length of database: 575,637,011
effective HSP length: 96
effective length of database: 416,537,747
effective search space used: 34572633001
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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