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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= NV060623.seq
         (682 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

X67698-1|CAA47928.1|  151|Homo sapiens protein ( H.sapiens tissu...    71   5e-12
BC002532-1|AAH02532.1|  151|Homo sapiens Niemann-Pick disease, t...    71   5e-12
AK222474-1|BAD96194.1|  151|Homo sapiens Niemann-Pick disease, t...    71   5e-12

>X67698-1|CAA47928.1|  151|Homo sapiens protein ( H.sapiens tissue
           specific mRNA. ).
          Length = 151

 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 25/61 (40%), Positives = 41/61 (67%)
 Frame = +1

Query: 289 VHGVIMNIPIPFPLPESDACKDNGLTCPLKEGTLADYKATLPILKSYPKVTVEVKWELQS 468
           VHG++M +P+PFP+PE D CK +G+ CP+++     Y   LP+   YP + + V+W+LQ 
Sbjct: 74  VHGILMGVPVPFPIPEPDGCK-SGINCPIQKDKTYSYLNKLPVKSEYPSIKLVVEWQLQD 132

Query: 469 E 471
           +
Sbjct: 133 D 133



 Score = 31.5 bits (68), Expect = 2.9
 Identities = 18/56 (32%), Positives = 25/56 (44%)
 Frame = +2

Query: 86  FFITAAVLLASAEAKFFKDCGSKLATVHNVTVSGCEESSSHCILKRNTDATIGLQF 253
           F + A    A AE   FKDCGS    +  V VS C   +  C L +    ++ + F
Sbjct: 8   FLLLALSTAAQAEPVQFKDCGSVDGVIKEVNVSPC--PTQPCQLSKGQSYSVNVTF 61


>BC002532-1|AAH02532.1|  151|Homo sapiens Niemann-Pick disease, type
           C2 protein.
          Length = 151

 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 25/61 (40%), Positives = 41/61 (67%)
 Frame = +1

Query: 289 VHGVIMNIPIPFPLPESDACKDNGLTCPLKEGTLADYKATLPILKSYPKVTVEVKWELQS 468
           VHG++M +P+PFP+PE D CK +G+ CP+++     Y   LP+   YP + + V+W+LQ 
Sbjct: 74  VHGILMGVPVPFPIPEPDGCK-SGINCPIQKDKTYSYLNKLPVKSEYPSIKLVVEWQLQD 132

Query: 469 E 471
           +
Sbjct: 133 D 133



 Score = 31.5 bits (68), Expect = 2.9
 Identities = 18/56 (32%), Positives = 25/56 (44%)
 Frame = +2

Query: 86  FFITAAVLLASAEAKFFKDCGSKLATVHNVTVSGCEESSSHCILKRNTDATIGLQF 253
           F + A    A AE   FKDCGS    +  V VS C   +  C L +    ++ + F
Sbjct: 8   FLLLALSTAAQAEPVQFKDCGSVDGVIKEVNVSPC--PTQPCQLSKGQSYSVNVTF 61


>AK222474-1|BAD96194.1|  151|Homo sapiens Niemann-Pick disease, type
           C2 precursor variant protein.
          Length = 151

 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 25/61 (40%), Positives = 41/61 (67%)
 Frame = +1

Query: 289 VHGVIMNIPIPFPLPESDACKDNGLTCPLKEGTLADYKATLPILKSYPKVTVEVKWELQS 468
           VHG++M +P+PFP+PE D CK +G+ CP+++     Y   LP+   YP + + V+W+LQ 
Sbjct: 74  VHGILMGVPVPFPIPEPDGCK-SGINCPIQKDKTYSYLNKLPVKSEYPSIKLVVEWQLQD 132

Query: 469 E 471
           +
Sbjct: 133 D 133



 Score = 30.3 bits (65), Expect = 6.6
 Identities = 17/56 (30%), Positives = 25/56 (44%)
 Frame = +2

Query: 86  FFITAAVLLASAEAKFFKDCGSKLATVHNVTVSGCEESSSHCILKRNTDATIGLQF 253
           F + A    A AE   F+DCGS    +  V VS C   +  C L +    ++ + F
Sbjct: 8   FLLLALSTAAQAEPVQFRDCGSVDGVIKEVNVSPC--PTQPCQLSKGQSYSVNVTF 61


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 97,317,775
Number of Sequences: 237096
Number of extensions: 2009190
Number of successful extensions: 4251
Number of sequences better than 10.0: 3
Number of HSP's better than 10.0 without gapping: 4103
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4248
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7727256732
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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