Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= NV060598.seq
(685 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X68836-1|CAA48726.1| 395|Homo sapiens S-adenosylmethionine synt... 156 8e-38
DQ083239-1|AAY85355.1| 395|Homo sapiens methionine adenosyltran... 156 8e-38
BC001854-1|AAH01854.1| 395|Homo sapiens methionine adenosyltran... 156 8e-38
BC001686-1|AAH01686.1| 395|Homo sapiens methionine adenosyltran... 156 8e-38
AC016753-1|AAY24339.1| 395|Homo sapiens unknown protein. 156 8e-38
X69078-1|CAA48822.1| 395|Homo sapiens methionine adenosyltransf... 152 1e-36
D49357-1|BAA08355.1| 395|Homo sapiens S-adenosylmethionine synt... 152 1e-36
BC018359-1|AAH18359.1| 395|Homo sapiens methionine adenosyltran... 152 1e-36
AL359195-2|CAI13695.1| 395|Homo sapiens methionine adenosyltran... 152 1e-36
AL359195-3|CAI13696.1| 145|Homo sapiens methionine adenosyltran... 89 1e-17
BC028352-1|AAH28352.1| 691|Homo sapiens TBC1 domain family, mem... 30 6.7
AK022147-1|BAB13971.1| 674|Homo sapiens protein ( Homo sapiens ... 30 8.8
>X68836-1|CAA48726.1| 395|Homo sapiens S-adenosylmethionine
synthetase protein.
Length = 395
Score = 156 bits (378), Expect = 8e-38
Identities = 69/86 (80%), Positives = 81/86 (94%)
Frame = +3
Query: 255 TGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGV 434
TGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL+QQSP+IA GV
Sbjct: 62 TGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGV 121
Query: 435 HXNRNDEEVGAGDQGLMFGYATDETK 512
H +RN+E++GAGDQGLMFGYATDET+
Sbjct: 122 HLDRNEEDIGAGDQGLMFGYATDETE 147
Score = 96.3 bits (229), Expect = 9e-20
Identities = 47/64 (73%), Positives = 54/64 (84%), Gaps = 1/64 (1%)
Frame = +1
Query: 67 MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 243
MNG + NG H +E+G+ FLFTSESVGEGHPDK+CDQISDA+LDAHL QDPDAKVACE
Sbjct: 1 MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57
Query: 244 TITK 255
T+ K
Sbjct: 58 TVAK 61
Score = 76.2 bits (179), Expect = 1e-13
Identities = 33/43 (76%), Positives = 37/43 (86%)
Frame = +2
Query: 509 EECMPLTVVLAHKLNQKIAELRRNGEFWWARPDSKTQVTCEYV 637
EECMPLT+VLAHKLN K+AELRRNG W RPDSKTQVT +Y+
Sbjct: 147 EECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYM 189
>DQ083239-1|AAY85355.1| 395|Homo sapiens methionine
adenosyltransferase II protein.
Length = 395
Score = 156 bits (378), Expect = 8e-38
Identities = 69/86 (80%), Positives = 81/86 (94%)
Frame = +3
Query: 255 TGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGV 434
TGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL+QQSP+IA GV
Sbjct: 62 TGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGV 121
Query: 435 HXNRNDEEVGAGDQGLMFGYATDETK 512
H +RN+E++GAGDQGLMFGYATDET+
Sbjct: 122 HLDRNEEDIGAGDQGLMFGYATDETE 147
Score = 96.3 bits (229), Expect = 9e-20
Identities = 47/64 (73%), Positives = 54/64 (84%), Gaps = 1/64 (1%)
Frame = +1
Query: 67 MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 243
MNG + NG H +E+G+ FLFTSESVGEGHPDK+CDQISDA+LDAHL QDPDAKVACE
Sbjct: 1 MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57
Query: 244 TITK 255
T+ K
Sbjct: 58 TVAK 61
Score = 76.2 bits (179), Expect = 1e-13
Identities = 33/43 (76%), Positives = 37/43 (86%)
Frame = +2
Query: 509 EECMPLTVVLAHKLNQKIAELRRNGEFWWARPDSKTQVTCEYV 637
EECMPLT+VLAHKLN K+AELRRNG W RPDSKTQVT +Y+
Sbjct: 147 EECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYM 189
>BC001854-1|AAH01854.1| 395|Homo sapiens methionine
adenosyltransferase II, alpha protein.
Length = 395
Score = 156 bits (378), Expect = 8e-38
Identities = 69/86 (80%), Positives = 81/86 (94%)
Frame = +3
Query: 255 TGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGV 434
TGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL+QQSP+IA GV
Sbjct: 62 TGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGV 121
Query: 435 HXNRNDEEVGAGDQGLMFGYATDETK 512
H +RN+E++GAGDQGLMFGYATDET+
Sbjct: 122 HLDRNEEDIGAGDQGLMFGYATDETE 147
Score = 96.3 bits (229), Expect = 9e-20
Identities = 47/64 (73%), Positives = 54/64 (84%), Gaps = 1/64 (1%)
Frame = +1
Query: 67 MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 243
MNG + NG H +E+G+ FLFTSESVGEGHPDK+CDQISDA+LDAHL QDPDAKVACE
Sbjct: 1 MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57
Query: 244 TITK 255
T+ K
Sbjct: 58 TVAK 61
Score = 76.2 bits (179), Expect = 1e-13
Identities = 33/43 (76%), Positives = 37/43 (86%)
Frame = +2
Query: 509 EECMPLTVVLAHKLNQKIAELRRNGEFWWARPDSKTQVTCEYV 637
EECMPLT+VLAHKLN K+AELRRNG W RPDSKTQVT +Y+
Sbjct: 147 EECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYM 189
>BC001686-1|AAH01686.1| 395|Homo sapiens methionine
adenosyltransferase II, alpha protein.
Length = 395
Score = 156 bits (378), Expect = 8e-38
Identities = 69/86 (80%), Positives = 81/86 (94%)
Frame = +3
Query: 255 TGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGV 434
TGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL+QQSP+IA GV
Sbjct: 62 TGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGV 121
Query: 435 HXNRNDEEVGAGDQGLMFGYATDETK 512
H +RN+E++GAGDQGLMFGYATDET+
Sbjct: 122 HLDRNEEDIGAGDQGLMFGYATDETE 147
Score = 96.3 bits (229), Expect = 9e-20
Identities = 47/64 (73%), Positives = 54/64 (84%), Gaps = 1/64 (1%)
Frame = +1
Query: 67 MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 243
MNG + NG H +E+G+ FLFTSESVGEGHPDK+CDQISDA+LDAHL QDPDAKVACE
Sbjct: 1 MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57
Query: 244 TITK 255
T+ K
Sbjct: 58 TVAK 61
Score = 76.2 bits (179), Expect = 1e-13
Identities = 33/43 (76%), Positives = 37/43 (86%)
Frame = +2
Query: 509 EECMPLTVVLAHKLNQKIAELRRNGEFWWARPDSKTQVTCEYV 637
EECMPLT+VLAHKLN K+AELRRNG W RPDSKTQVT +Y+
Sbjct: 147 EECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYM 189
>AC016753-1|AAY24339.1| 395|Homo sapiens unknown protein.
Length = 395
Score = 156 bits (378), Expect = 8e-38
Identities = 69/86 (80%), Positives = 81/86 (94%)
Frame = +3
Query: 255 TGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGV 434
TGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL+QQSP+IA GV
Sbjct: 62 TGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGV 121
Query: 435 HXNRNDEEVGAGDQGLMFGYATDETK 512
H +RN+E++GAGDQGLMFGYATDET+
Sbjct: 122 HLDRNEEDIGAGDQGLMFGYATDETE 147
Score = 96.3 bits (229), Expect = 9e-20
Identities = 47/64 (73%), Positives = 54/64 (84%), Gaps = 1/64 (1%)
Frame = +1
Query: 67 MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 243
MNG + NG H +E+G+ FLFTSESVGEGHPDK+CDQISDA+LDAHL QDPDAKVACE
Sbjct: 1 MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57
Query: 244 TITK 255
T+ K
Sbjct: 58 TVAK 61
Score = 76.2 bits (179), Expect = 1e-13
Identities = 33/43 (76%), Positives = 37/43 (86%)
Frame = +2
Query: 509 EECMPLTVVLAHKLNQKIAELRRNGEFWWARPDSKTQVTCEYV 637
EECMPLT+VLAHKLN K+AELRRNG W RPDSKTQVT +Y+
Sbjct: 147 EECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYM 189
>X69078-1|CAA48822.1| 395|Homo sapiens methionine
adenosyltransferase protein.
Length = 395
Score = 152 bits (368), Expect = 1e-36
Identities = 67/86 (77%), Positives = 81/86 (94%)
Frame = +3
Query: 255 TGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGV 434
TGMVLLCGEITS A VDYQ+VVR+T+KHIGYDDS+KGFD+KTC+V++AL+QQSP+IA V
Sbjct: 62 TGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCV 121
Query: 435 HXNRNDEEVGAGDQGLMFGYATDETK 512
H +RN+E+VGAGDQGLMFGYATDET+
Sbjct: 122 HLDRNEEDVGAGDQGLMFGYATDETE 147
Score = 90.2 bits (214), Expect = 6e-18
Identities = 39/52 (75%), Positives = 47/52 (90%)
Frame = +1
Query: 100 YDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETITK 255
+ + +G VF+FTSESVGEGHPDK+CDQISDA+LDAHL QDP+AKVACET+ K
Sbjct: 11 HSLSEG-VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCK 61
Score = 70.1 bits (164), Expect = 7e-12
Identities = 29/43 (67%), Positives = 37/43 (86%)
Frame = +2
Query: 509 EECMPLTVVLAHKLNQKIAELRRNGEFWWARPDSKTQVTCEYV 637
EECMPLT++LAHKLN ++A+LRR+G W RPDSKTQVT +Y+
Sbjct: 147 EECMPLTIILAHKLNARMADLRRSGLLPWLRPDSKTQVTVQYM 189
>D49357-1|BAA08355.1| 395|Homo sapiens S-adenosylmethionine
synthetase protein.
Length = 395
Score = 152 bits (368), Expect = 1e-36
Identities = 67/86 (77%), Positives = 81/86 (94%)
Frame = +3
Query: 255 TGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGV 434
TGMVLLCGEITS A VDYQ+VVR+T+KHIGYDDS+KGFD+KTC+V++AL+QQSP+IA V
Sbjct: 62 TGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCV 121
Query: 435 HXNRNDEEVGAGDQGLMFGYATDETK 512
H +RN+E+VGAGDQGLMFGYATDET+
Sbjct: 122 HLDRNEEDVGAGDQGLMFGYATDETE 147
Score = 90.2 bits (214), Expect = 6e-18
Identities = 39/52 (75%), Positives = 47/52 (90%)
Frame = +1
Query: 100 YDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETITK 255
+ + +G VF+FTSESVGEGHPDK+CDQISDA+LDAHL QDP+AKVACET+ K
Sbjct: 11 HSLSEG-VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCK 61
Score = 70.1 bits (164), Expect = 7e-12
Identities = 29/43 (67%), Positives = 37/43 (86%)
Frame = +2
Query: 509 EECMPLTVVLAHKLNQKIAELRRNGEFWWARPDSKTQVTCEYV 637
EECMPLT++LAHKLN ++A+LRR+G W RPDSKTQVT +Y+
Sbjct: 147 EECMPLTIILAHKLNARMADLRRSGLLPWLRPDSKTQVTVQYM 189
>BC018359-1|AAH18359.1| 395|Homo sapiens methionine
adenosyltransferase I, alpha protein.
Length = 395
Score = 152 bits (368), Expect = 1e-36
Identities = 67/86 (77%), Positives = 81/86 (94%)
Frame = +3
Query: 255 TGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGV 434
TGMVLLCGEITS A VDYQ+VVR+T+KHIGYDDS+KGFD+KTC+V++AL+QQSP+IA V
Sbjct: 62 TGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCV 121
Query: 435 HXNRNDEEVGAGDQGLMFGYATDETK 512
H +RN+E+VGAGDQGLMFGYATDET+
Sbjct: 122 HLDRNEEDVGAGDQGLMFGYATDETE 147
Score = 90.2 bits (214), Expect = 6e-18
Identities = 39/52 (75%), Positives = 47/52 (90%)
Frame = +1
Query: 100 YDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETITK 255
+ + +G VF+FTSESVGEGHPDK+CDQISDA+LDAHL QDP+AKVACET+ K
Sbjct: 11 HSLSEG-VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCK 61
Score = 70.1 bits (164), Expect = 7e-12
Identities = 29/43 (67%), Positives = 37/43 (86%)
Frame = +2
Query: 509 EECMPLTVVLAHKLNQKIAELRRNGEFWWARPDSKTQVTCEYV 637
EECMPLT++LAHKLN ++A+LRR+G W RPDSKTQVT +Y+
Sbjct: 147 EECMPLTIILAHKLNARMADLRRSGLLPWLRPDSKTQVTVQYM 189
>AL359195-2|CAI13695.1| 395|Homo sapiens methionine
adenosyltransferase I, alpha protein.
Length = 395
Score = 152 bits (368), Expect = 1e-36
Identities = 67/86 (77%), Positives = 81/86 (94%)
Frame = +3
Query: 255 TGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGV 434
TGMVLLCGEITS A VDYQ+VVR+T+KHIGYDDS+KGFD+KTC+V++AL+QQSP+IA V
Sbjct: 62 TGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCV 121
Query: 435 HXNRNDEEVGAGDQGLMFGYATDETK 512
H +RN+E+VGAGDQGLMFGYATDET+
Sbjct: 122 HLDRNEEDVGAGDQGLMFGYATDETE 147
Score = 90.2 bits (214), Expect = 6e-18
Identities = 39/52 (75%), Positives = 47/52 (90%)
Frame = +1
Query: 100 YDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETITK 255
+ + +G VF+FTSESVGEGHPDK+CDQISDA+LDAHL QDP+AKVACET+ K
Sbjct: 11 HSLSEG-VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCK 61
Score = 70.1 bits (164), Expect = 7e-12
Identities = 29/43 (67%), Positives = 37/43 (86%)
Frame = +2
Query: 509 EECMPLTVVLAHKLNQKIAELRRNGEFWWARPDSKTQVTCEYV 637
EECMPLT++LAHKLN ++A+LRR+G W RPDSKTQVT +Y+
Sbjct: 147 EECMPLTIILAHKLNARMADLRRSGLLPWLRPDSKTQVTVQYM 189
>AL359195-3|CAI13696.1| 145|Homo sapiens methionine
adenosyltransferase I, alpha protein.
Length = 145
Score = 89.0 bits (211), Expect = 1e-17
Identities = 40/62 (64%), Positives = 53/62 (85%), Gaps = 3/62 (4%)
Frame = +3
Query: 336 HIGYDDSSK---GFDYKTCSVMLALDQQSPNIAAGVHXNRNDEEVGAGDQGLMFGYATDE 506
H+ D ++K GFD+KTC+V++AL+QQSP+IA VH +RN+E+VGAGDQGLMFGYATDE
Sbjct: 23 HLKQDPNAKVACGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQGLMFGYATDE 82
Query: 507 TK 512
T+
Sbjct: 83 TE 84
Score = 72.1 bits (169), Expect = 2e-12
Identities = 30/34 (88%), Positives = 33/34 (97%)
Frame = +1
Query: 139 ESVGEGHPDKMCDQISDAILDAHLNQDPDAKVAC 240
ESVGEGHPDK+CDQISDA+LDAHL QDP+AKVAC
Sbjct: 1 ESVGEGHPDKICDQISDAVLDAHLKQDPNAKVAC 34
Score = 70.1 bits (164), Expect = 7e-12
Identities = 29/43 (67%), Positives = 37/43 (86%)
Frame = +2
Query: 509 EECMPLTVVLAHKLNQKIAELRRNGEFWWARPDSKTQVTCEYV 637
EECMPLT++LAHKLN ++A+LRR+G W RPDSKTQVT +Y+
Sbjct: 84 EECMPLTIILAHKLNARMADLRRSGLLPWLRPDSKTQVTVQYM 126
>BC028352-1|AAH28352.1| 691|Homo sapiens TBC1 domain family, member
15 protein.
Length = 691
Score = 30.3 bits (65), Expect = 6.7
Identities = 20/66 (30%), Positives = 31/66 (46%)
Frame = +1
Query: 28 WANSKFRMPETSKMNGYAKTNGHSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAH 207
W K + P T+ M G++K + +D GS S + P +M D +SDAI
Sbjct: 235 WKKIK-KDPYTATMIGFSKVTNYIFDSLRGS-----DPSTHQRPPSEMADFLSDAIPGLK 288
Query: 208 LNQDPD 225
+NQ +
Sbjct: 289 INQQEE 294
>AK022147-1|BAB13971.1| 674|Homo sapiens protein ( Homo sapiens
cDNA FLJ12085 fis, clone HEMBB1002510, weakly similar to
GYP7 PROTEIN. ).
Length = 674
Score = 29.9 bits (64), Expect = 8.8
Identities = 18/58 (31%), Positives = 28/58 (48%)
Frame = +1
Query: 52 PETSKMNGYAKTNGHSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPD 225
P T+ M G++K + +D GS S + P +M D +SDAI +NQ +
Sbjct: 225 PYTATMIGFSKVTNYIFDSLRGS-----DPSTHQRPPSEMADFLSDAIPGLKINQQEE 277
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 114,072,753
Number of Sequences: 237096
Number of extensions: 2672779
Number of successful extensions: 8943
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 8762
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8943
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7783251346
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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