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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= NV060486.seq
         (684 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_O75390 Cluster: Citrate synthase, mitochondrial precurs...   111   1e-23
UniRef50_P20115 Cluster: Citrate synthase 4, mitochondrial precu...    99   5e-20
UniRef50_Q9M1D3 Cluster: Citrate synthase 5, mitochondrial precu...   100   7e-20
UniRef50_Q4QDX3 Cluster: Probable citrate synthase, mitochondria...    89   1e-16
UniRef50_A6S819 Cluster: Citrate synthase; n=1; Botryotinia fuck...    81   3e-14
UniRef50_UPI0000D9A0A8 Cluster: PREDICTED: similar to citrate sy...    77   4e-13
UniRef50_A0DZ50 Cluster: Citrate synthase; n=6; Paramecium tetra...    67   3e-10
UniRef50_Q6JGH9 Cluster: Citrate synthase; n=17; Desulfuromonada...    63   7e-09
UniRef50_Q4N4H4 Cluster: Citrate synthase, putative; n=3; Piropl...    56   1e-06
UniRef50_P43635 Cluster: Citrate synthase 3; n=7; Saccharomyceta...    56   1e-06
UniRef50_UPI00015B4F54 Cluster: PREDICTED: hypothetical protein;...    55   1e-06
UniRef50_Q95TZ4 Cluster: Citrate synthase; n=1; Drosophila melan...    55   1e-06
UniRef50_UPI00006CBE2B Cluster: citrate synthase; n=1; Tetrahyme...    55   2e-06
UniRef50_A4ZVV6 Cluster: Mitochondrial citrate synthase 1; n=1; ...    54   4e-06
UniRef50_UPI00006CFBEC Cluster: Citrate synthase family protein;...    53   6e-06
UniRef50_UPI0000DB6B6F Cluster: PREDICTED: similar to citrate sy...    48   2e-04
UniRef50_Q8F887 Cluster: Citrate synthase; n=4; Leptospira|Rep: ...    42   0.014
UniRef50_A5KE63 Cluster: Citrate synthase, mitochondrial, putati...    38   0.30 
UniRef50_Q8NSL1 Cluster: 2-methylcitrate synthase 2; n=29; Bacte...    36   0.92 
UniRef50_O75011 Cluster: Serine/threonine-protein kinase nak1; n...    35   1.6  
UniRef50_Q9LXS7 Cluster: Citrate synthase 1, peroxisomal precurs...    35   2.1  
UniRef50_Q7W5Q6 Cluster: 2-methylcitrate synthase; n=122; Bacter...    34   2.8  
UniRef50_A6T3T1 Cluster: 2-methylcitrate synthase; n=60; Bacteri...    34   2.8  
UniRef50_A7S7M5 Cluster: Predicted protein; n=1; Nematostella ve...    34   2.8  
UniRef50_Q1E3Z8 Cluster: Putative uncharacterized protein; n=1; ...    34   2.8  
UniRef50_Q9PKT4 Cluster: Putative uncharacterized protein; n=3; ...    33   4.9  
UniRef50_Q6LFK6 Cluster: Putative uncharacterized protein; n=2; ...    33   6.5  
UniRef50_Q823X4 Cluster: Polymorphic outer membrane protein G fa...    33   8.6  
UniRef50_A2F9Q9 Cluster: Putative uncharacterized protein; n=1; ...    33   8.6  

>UniRef50_O75390 Cluster: Citrate synthase, mitochondrial precursor;
           n=140; cellular organisms|Rep: Citrate synthase,
           mitochondrial precursor - Homo sapiens (Human)
          Length = 466

 Score =  111 bits (268), Expect = 1e-23
 Identities = 64/144 (44%), Positives = 84/144 (58%), Gaps = 3/144 (2%)
 Frame = +2

Query: 257 EVTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSIPECQQQLPKAKGGEEPLPEVFSG 436
           ++TVDMMYGGMRG+KGLV+ETSVLD DEGIRFRG SIPECQ+ LPKAKGGEEPLPE    
Sbjct: 62  QITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLPKAKGGEEPLPEGLFW 121

Query: 437 FSSLAIYPPKRK*SAV*R-MGGEGGYRLT*XQC*TXCPANCIPCRSSRLPSPHSTVN--L 607
                  P + + S + +                   P N  P   S+L +  + +N   
Sbjct: 122 LLVTGHIPTEEQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHP--MSQLSAAVTALNSES 179

Query: 608 NXLKPTQXGVHKSQYWEYVYXDTM 679
           N  +    G+ +++YWE +Y D+M
Sbjct: 180 NFARAYAQGISRTKYWELIYEDSM 203



 Score = 88.2 bits (209), Expect = 2e-16
 Identities = 45/79 (56%), Positives = 51/79 (64%), Gaps = 1/79 (1%)
 Frame = +1

Query: 400 GWRRTTTRSLFWLLVTGDIPTEAQVKRCLKN-GRRGRIPAHVVXMLNXMPGKLHPMSQFS 576
           G        LFWLLVTG IPTE QV    K   +R  +P+HVV ML+  P  LHPMSQ S
Sbjct: 110 GGEEPLPEGLFWLLVTGHIPTEEQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLS 169

Query: 577 AAVTALNSESKXAKAYSXG 633
           AAVTALNSES  A+AY+ G
Sbjct: 170 AAVTALNSESNFARAYAQG 188



 Score = 46.0 bits (104), Expect = 9e-04
 Identities = 26/62 (41%), Positives = 34/62 (54%)
 Frame = +3

Query: 69  MALFRITSSRLVELQKACPTATVLLRGLSAEQTNLKSILQEKIPKEQEKIREFRKKHGST 248
           MAL    +  L     +C    +  R  SA  TNLK IL + IPKEQ +I+ FR++HG T
Sbjct: 1   MALLTAAARLLGTKNASC--LVLAARHASASSTNLKDILADLIPKEQARIKTFRQQHGKT 58

Query: 249 KV 254
            V
Sbjct: 59  VV 60


>UniRef50_P20115 Cluster: Citrate synthase 4, mitochondrial
           precursor; n=27; Eukaryota|Rep: Citrate synthase 4,
           mitochondrial precursor - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 474

 Score =   99 bits (238), Expect = 5e-20
 Identities = 55/141 (39%), Positives = 73/141 (51%), Gaps = 1/141 (0%)
 Frame = +2

Query: 260 VTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSIPECQQQLPKAKGGEEPLPEVFSGF 439
           +TVDM+ GGMRG+ GL+WETS+LD +EGIRFRGLSIPECQ+ LP A+ G EPLPE     
Sbjct: 71  ITVDMVIGGMRGMTGLLWETSLLDPEEGIRFRGLSIPECQKVLPTAQSGAEPLPEGLLWL 130

Query: 440 SSLAIYPPKRK*SAV*R-MGGEGGYRLT*XQC*TXCPANCIPCRSSRLPSPHSTVNLNXL 616
                 P K +  A+ + +                 P+   P            V     
Sbjct: 131 LLTGKVPSKEQVEALSKDLANRAAVPDYVYNAIDALPSTAHPMTQFASGVMALQVQSEFQ 190

Query: 617 KPTQXGVHKSQYWEYVYXDTM 679
           K  + G+HKS++WE  Y D +
Sbjct: 191 KAYENGIHKSKFWEPTYEDCL 211



 Score = 60.1 bits (139), Expect = 5e-08
 Identities = 27/70 (38%), Positives = 43/70 (61%), Gaps = 1/70 (1%)
 Frame = +1

Query: 427 LFWLLVTGDIPTEAQVKRCLKN-GRRGRIPAHVVXMLNXMPGKLHPMSQFSAAVTALNSE 603
           L WLL+TG +P++ QV+   K+   R  +P +V   ++ +P   HPM+QF++ V AL  +
Sbjct: 127 LLWLLLTGKVPSKEQVEALSKDLANRAAVPDYVYNAIDALPSTAHPMTQFASGVMALQVQ 186

Query: 604 SKXAKAYSXG 633
           S+  KAY  G
Sbjct: 187 SEFQKAYENG 196



 Score = 34.7 bits (76), Expect = 2.1
 Identities = 16/62 (25%), Positives = 36/62 (58%)
 Frame = +3

Query: 69  MALFRITSSRLVELQKACPTATVLLRGLSAEQTNLKSILQEKIPKEQEKIREFRKKHGST 248
           ++ F    SR+   Q +   +   ++  S+   +LKS LQE IP++Q+++++ + +HG  
Sbjct: 7   VSAFTRLRSRVQGQQSSLSNSVRWIQMQSSTDLDLKSQLQELIPEQQDRLKKLKSEHGKV 66

Query: 249 KV 254
           ++
Sbjct: 67  QL 68


>UniRef50_Q9M1D3 Cluster: Citrate synthase 5, mitochondrial
           precursor; n=26; Eukaryota|Rep: Citrate synthase 5,
           mitochondrial precursor - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 433

 Score = 99.5 bits (237), Expect = 7e-20
 Identities = 58/141 (41%), Positives = 76/141 (53%), Gaps = 1/141 (0%)
 Frame = +2

Query: 260 VTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSIPECQQQLPKAKGGEEPLPEVFSGF 439
           +TVDM+ GGMRG+ GL+WETS+LDADEGIRFRG+SIPECQ+ LP A+ GEEPLPE     
Sbjct: 36  ITVDMVLGGMRGMTGLLWETSLLDADEGIRFRGMSIPECQKILPSAESGEEPLPESLLWL 95

Query: 440 SSLAIYPPKRK*SAV*RMGGEGGYRLT*XQC*TXCPANCIPCRSSRLPSPHSTVNLNXLK 619
                 P K + +A   +  E  +R          P+   P            V     K
Sbjct: 96  LLTGKVPTKEQANA---LSTELAHRAA-VPAIDALPSTAHPMTQFASGVMALQVQSEFQK 151

Query: 620 PTQXG-VHKSQYWEYVYXDTM 679
             + G + KS+YWE  + D +
Sbjct: 152 AYEQGDISKSKYWEPTFEDAL 172



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 27/71 (38%), Positives = 39/71 (54%), Gaps = 1/71 (1%)
 Frame = +1

Query: 424 SLFWLLVTGDIPTEAQVKRCLKN-GRRGRIPAHVVXMLNXMPGKLHPMSQFSAAVTALNS 600
           SL WLL+TG +PT+ Q          R  +PA     ++ +P   HPM+QF++ V AL  
Sbjct: 91  SLLWLLLTGKVPTKEQANALSTELAHRAAVPA-----IDALPSTAHPMTQFASGVMALQV 145

Query: 601 ESKXAKAYSXG 633
           +S+  KAY  G
Sbjct: 146 QSEFQKAYEQG 156


>UniRef50_Q4QDX3 Cluster: Probable citrate synthase, mitochondrial
           precursor; n=9; Trypanosomatidae|Rep: Probable citrate
           synthase, mitochondrial precursor - Leishmania major
          Length = 470

 Score = 88.6 bits (210), Expect = 1e-16
 Identities = 39/56 (69%), Positives = 47/56 (83%)
 Frame = +2

Query: 257 EVTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSIPECQQQLPKAKGGEEPLPE 424
           + T+D +YGGMRGI GLV+E S+LD  EGIRFRGL+I ECQ+ LPKA GG+EPLPE
Sbjct: 54  DATIDAVYGGMRGITGLVYEPSLLDPAEGIRFRGLTILECQEMLPKAPGGKEPLPE 109



 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 30/83 (36%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
 Frame = +1

Query: 400 GWRRTTTRSLFWLLVTGDIPTEAQVKRCLKNGRRGRIPAHVVXM---LNXMPGKLHPMSQ 570
           G +     ++FWLL+TG++PTE QV+       R   P  +      +  +P   HPM+ 
Sbjct: 102 GGKEPLPEAMFWLLMTGEVPTEEQVRGLNAELHRRADPEAIAAAQKAIAALPRNAHPMTA 161

Query: 571 FSAAVTALNSESKXAKAYSXGRA 639
           FS  V AL S SK A AY+ G++
Sbjct: 162 FSVGVLALQSYSKFAAAYAAGKS 184


>UniRef50_A6S819 Cluster: Citrate synthase; n=1; Botryotinia
           fuckeliana B05.10|Rep: Citrate synthase - Botryotinia
           fuckeliana B05.10
          Length = 534

 Score = 80.6 bits (190), Expect = 3e-14
 Identities = 35/56 (62%), Positives = 43/56 (76%)
 Frame = +2

Query: 257 EVTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSIPECQQQLPKAKGGEEPLPE 424
           EV ++   GGMRG+K +VWE SVLDADEGIRF G +I +CQ++LPK K G E LPE
Sbjct: 96  EVKIENTIGGMRGLKAMVWEGSVLDADEGIRFHGRTIKDCQKELPKGKSGTEMLPE 151



 Score = 66.5 bits (155), Expect = 6e-10
 Identities = 32/71 (45%), Positives = 47/71 (66%), Gaps = 1/71 (1%)
 Frame = +1

Query: 424 SLFWLLVTGDIPTEAQVKRCLKN-GRRGRIPAHVVXMLNXMPGKLHPMSQFSAAVTALNS 600
           ++FWLL+TG IP+ +QV++  K    +  +P  V  ML+  P  LHPM+QF+ AV+AL+ 
Sbjct: 152 AMFWLLLTGQIPSTSQVRQFSKELAEQAALPDFVNKMLDNFPKDLHPMTQFAMAVSALSH 211

Query: 601 ESKXAKAYSXG 633
            SK AK+Y  G
Sbjct: 212 TSKFAKSYEKG 222


>UniRef50_UPI0000D9A0A8 Cluster: PREDICTED: similar to citrate
           synthase precursor, isoform a; n=1; Macaca mulatta|Rep:
           PREDICTED: similar to citrate synthase precursor,
           isoform a - Macaca mulatta
          Length = 112

 Score = 77.0 bits (181), Expect = 4e-13
 Identities = 36/49 (73%), Positives = 40/49 (81%)
 Frame = +2

Query: 275 MYGGMRGIKGLVWETSVLDADEGIRFRGLSIPECQQQLPKAKGGEEPLP 421
           MYG MRGIKGLV++TSVLD  EG  F+G SIPE Q+ LPKAKGGE PLP
Sbjct: 1   MYGDMRGIKGLVYKTSVLDPHEGFCFQGFSIPEYQKLLPKAKGGEGPLP 49


>UniRef50_A0DZ50 Cluster: Citrate synthase; n=6; Paramecium
           tetraurelia|Rep: Citrate synthase - Paramecium
           tetraurelia
          Length = 459

 Score = 67.3 bits (157), Expect = 3e-10
 Identities = 48/144 (33%), Positives = 67/144 (46%), Gaps = 3/144 (2%)
 Frame = +2

Query: 257 EVTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSIPECQQQLPKAKGGEEPLPEVFSG 436
           +VTVD   GGMR + GL ++ S+LDA  GI  R  +IPE Q+ L KA+ G EPLPE    
Sbjct: 53  KVTVDQAIGGMRNVFGLFYDASLLDAKTGITMRDYNIPELQEYLQKAENGHEPLPEALFW 112

Query: 437 FSSLAIYPPKRK*SAV*RMGGEGGYRLT*XQ---C*TXCPANCIPCRSSRLPSPHSTVNL 607
                 +P +++ + V +   + G   +  Q         A+ +   S  L         
Sbjct: 113 LLCTGDFPSEQEFADVQQEWKQRGQLDSETQKFILSLPKAAHPMTMLSQTLLFLQKDSQF 172

Query: 608 NXLKPTQXGVHKSQYWEYVYXDTM 679
             +   Q  V K QYWEY Y D M
Sbjct: 173 QQVY-DQGKVSKPQYWEYFYEDAM 195



 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 1/76 (1%)
 Frame = +1

Query: 424 SLFWLLVTGDIPTEAQVKRCLKNGR-RGRIPAHVVXMLNXMPGKLHPMSQFSAAVTALNS 600
           +LFWLL TGD P+E +     +  + RG++ +     +  +P   HPM+  S  +  L  
Sbjct: 109 ALFWLLCTGDFPSEQEFADVQQEWKQRGQLDSETQKFILSLPKAAHPMTMLSQTLLFLQK 168

Query: 601 ESKXAKAYSXGRAQIP 648
           +S+  + Y  G+   P
Sbjct: 169 DSQFQQVYDQGKVSKP 184


>UniRef50_Q6JGH9 Cluster: Citrate synthase; n=17;
           Desulfuromonadales|Rep: Citrate synthase - Geobacter
           metallireducens
          Length = 441

 Score = 62.9 bits (146), Expect = 7e-09
 Identities = 30/58 (51%), Positives = 37/58 (63%)
 Frame = +2

Query: 257 EVTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSIPECQQQLPKAKGGEEPLPEVF 430
           +VT+D   GG R I+ LV + S LD  EGIRFRG +IPE  + LPKA G + P  E F
Sbjct: 32  QVTIDQAIGGARDIRSLVTDISYLDPQEGIRFRGKTIPETFEALPKASGSDYPTVESF 89



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 25/75 (33%), Positives = 43/75 (57%), Gaps = 1/75 (1%)
 Frame = +1

Query: 415 TTRSLFWLLVTGDIPTEAQVKRCLKNGR-RGRIPAHVVXMLNXMPGKLHPMSQFSAAVTA 591
           T  S ++ L+TG++PT+AQV   +   + R  +P +V   ++ +P + HPM   S  + A
Sbjct: 85  TVESFWYFLLTGEVPTQAQVDEVVAEWKTRQVVPQYVFDAISALPKESHPMVMLSVGILA 144

Query: 592 LNSESKXAKAYSXGR 636
           L  +SK A  Y+ G+
Sbjct: 145 LQKDSKFAGFYNSGK 159


>UniRef50_Q4N4H4 Cluster: Citrate synthase, putative; n=3;
           Piroplasmida|Rep: Citrate synthase, putative - Theileria
           parva
          Length = 676

 Score = 55.6 bits (128), Expect = 1e-06
 Identities = 26/70 (37%), Positives = 41/70 (58%), Gaps = 1/70 (1%)
 Frame = +1

Query: 418 TRSLFWLLVTGDIPTEAQVKRC-LKNGRRGRIPAHVVXMLNXMPGKLHPMSQFSAAVTAL 594
           T S+ W L+TG++P+   V     +  RR  +P HV  +++  P   HPM+Q+  AV+AL
Sbjct: 321 TESVLWFLLTGEVPSPVDVDDLSYELYRRSTVPEHVYKVIDGFPTDAHPMTQYITAVSAL 380

Query: 595 NSESKXAKAY 624
            +ES   +AY
Sbjct: 381 QTESVFREAY 390



 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 21/45 (46%), Positives = 30/45 (66%)
 Frame = +2

Query: 257 EVTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSIPECQQQLP 391
           EVT+ M++ G++ +  +V ETS LD   GIRFRGL++ E    LP
Sbjct: 268 EVTLSMLFSGLKDVPAMVTETSELDPFNGIRFRGLTVDEMLTALP 312


>UniRef50_P43635 Cluster: Citrate synthase 3; n=7;
           Saccharomycetales|Rep: Citrate synthase 3 -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 486

 Score = 55.6 bits (128), Expect = 1e-06
 Identities = 24/56 (42%), Positives = 37/56 (66%), Gaps = 1/56 (1%)
 Frame = +2

Query: 260 VTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSIPECQQQLPKAK-GGEEPLPE 424
           +T+  + GGMRG + + W+ + LD + GI+F+GL+I ECQ +LP     G+  LPE
Sbjct: 59  ITISSVLGGMRGNQSMFWQGTSLDPEHGIKFQGLTIEECQNRLPNTGIDGDNFLPE 114



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 25/72 (34%), Positives = 39/72 (54%), Gaps = 2/72 (2%)
 Frame = +1

Query: 424 SLFWLLVTGDIPTEAQVKRCLKN-GRRGR-IPAHVVXMLNXMPGKLHPMSQFSAAVTALN 597
           S+ WLL+TG +PT  Q     K    RGR +P +   +L+ +P  +HPM+Q +  + ++N
Sbjct: 115 SMLWLLMTGGVPTFQQAASFRKELAIRGRKLPHYTEKVLSSLPKDMHPMTQLAIGLASMN 174

Query: 598 SESKXAKAYSXG 633
             S  A  Y  G
Sbjct: 175 KGSLFATNYQKG 186


>UniRef50_UPI00015B4F54 Cluster: PREDICTED: hypothetical protein;
           n=1; Nasonia vitripennis|Rep: PREDICTED: hypothetical
           protein - Nasonia vitripennis
          Length = 479

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 26/56 (46%), Positives = 39/56 (69%)
 Frame = +2

Query: 257 EVTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSIPECQQQLPKAKGGEEPLPE 424
           ++TV+ +Y G+ G+  L+ ETS +D+  GI++RGLSIPE  Q LP+   G+ P PE
Sbjct: 47  QITVNDIYRGLDGVTALIRETSEIDSQCGIKYRGLSIPELYQLLPRR--GKSPSPE 100



 Score = 33.9 bits (74), Expect = 3.7
 Identities = 15/30 (50%), Positives = 21/30 (70%)
 Frame = +3

Query: 153 SAEQTNLKSILQEKIPKEQEKIREFRKKHG 242
           SA  T+LK  L EKIP   + +R+FR++HG
Sbjct: 12  SAGATDLKEALCEKIPLHHDLLRKFRQQHG 41


>UniRef50_Q95TZ4 Cluster: Citrate synthase; n=1; Drosophila
           melanogaster|Rep: Citrate synthase - Drosophila
           melanogaster (Fruit fly)
          Length = 478

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 25/79 (31%), Positives = 45/79 (56%), Gaps = 1/79 (1%)
 Frame = +1

Query: 400 GWRRTTTRSLFWLLVTGDIPTEAQVKRCLKNG-RRGRIPAHVVXMLNXMPGKLHPMSQFS 576
           G +  T    F+LL +G +PT+ + +       +RG +P + + M++ M  ++HPM+Q  
Sbjct: 111 GTQEGTPEGCFFLLTSGSMPTKKEAQEVTNEWLKRGSVPRYCLRMIDSMDKRVHPMAQLC 170

Query: 577 AAVTALNSESKXAKAYSXG 633
           AA   LN +S+  +AY+ G
Sbjct: 171 AASACLNPQSQFVEAYTKG 189



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 40/148 (27%), Positives = 69/148 (46%), Gaps = 7/148 (4%)
 Frame = +2

Query: 257 EVTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSIPECQQQLPKA-KGGEEPLPEVFS 433
           +++V+ + GGMRG+  L  ETS LD ++GI +RG  + +   +LP+  +G +E  PE   
Sbjct: 62  QISVNSVIGGMRGLPLLFCETSSLDKNKGIYYRGKLLKDVCAKLPRVQEGTQEGTPEGCF 121

Query: 434 GFSSLAIYPPKRK*SAV----*RMGGEGGY--RLT*XQC*TXCPANCIPCRSSRLPSPHS 595
              +    P K++   V     + G    Y  R+         P   + C +S   +P S
Sbjct: 122 FLLTSGSMPTKKEAQEVTNEWLKRGSVPRYCLRMIDSMDKRVHPMAQL-CAASACLNPQS 180

Query: 596 TVNLNXLKPTQXGVHKSQYWEYVYXDTM 679
                 ++    G  ++ YW+Y Y D+M
Sbjct: 181 ----QFVEAYTKGARRADYWKYSYEDSM 204


>UniRef50_UPI00006CBE2B Cluster: citrate synthase; n=1; Tetrahymena
           thermophila SB210|Rep: citrate synthase - Tetrahymena
           thermophila SB210
          Length = 474

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 27/64 (42%), Positives = 39/64 (60%), Gaps = 8/64 (12%)
 Frame = +2

Query: 257 EVTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSIPECQQQLPKAK--------GGEE 412
           E+TV+   GGMRGI+ L ++ S +D  +G+ FRG SIPE  + LPK +          ++
Sbjct: 54  EITVNQALGGMRGIRALFYDQSTVDPIDGVMFRGYSIPELHELLPKLRKPSAEDFQSDQQ 113

Query: 413 PLPE 424
           PLPE
Sbjct: 114 PLPE 117



 Score = 46.0 bits (104), Expect = 9e-04
 Identities = 22/71 (30%), Positives = 40/71 (56%), Gaps = 1/71 (1%)
 Frame = +1

Query: 427 LFWLLVTGDIPTEAQVKRCLKNGR-RGRIPAHVVXMLNXMPGKLHPMSQFSAAVTALNSE 603
           LF+LL+TG++P+  QV+        RG++   ++  +N +  K+HPM+  S A+      
Sbjct: 119 LFFLLLTGELPSYHQVELIRHEWDVRGKVSDELINFINRLDNKMHPMTMLSLAILYEQKT 178

Query: 604 SKXAKAYSXGR 636
           SK A+ Y+  +
Sbjct: 179 SKFAQLYNESK 189


>UniRef50_A4ZVV6 Cluster: Mitochondrial citrate synthase 1; n=1;
           Toxoplasma gondii|Rep: Mitochondrial citrate synthase 1
           - Toxoplasma gondii
          Length = 554

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 25/56 (44%), Positives = 36/56 (64%)
 Frame = +2

Query: 257 EVTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSIPECQQQLPKAKGGEEPLPE 424
           E T+  + GGMRG+  ++ ETS L A++GI +RGL+I EC  +LP+    E P  E
Sbjct: 143 EATLSTVCGGMRGLTAILTETSTLHAEKGILYRGLTINECLAKLPRMHKEEYPAVE 198



 Score = 39.5 bits (88), Expect = 0.075
 Identities = 28/79 (35%), Positives = 37/79 (46%), Gaps = 13/79 (16%)
 Frame = +1

Query: 427 LFWLLVTGDIPTEAQVKRCLKNGRRGR-------------IPAHVVXMLNXMPGKLHPMS 567
           L W L+TG IPT  +V+  L N                  IP HV  +L+ +P   HPM+
Sbjct: 200 LIWFLMTGSIPTVNEVE-LLSNALYALSLSSASSSPSAPFIPPHVGKVLDAVPPSTHPMT 258

Query: 568 QFSAAVTALNSESKXAKAY 624
           Q   A  AL   S+ A+AY
Sbjct: 259 QLVMAAAALQPTSELAQAY 277


>UniRef50_UPI00006CFBEC Cluster: Citrate synthase family protein;
           n=1; Tetrahymena thermophila SB210|Rep: Citrate synthase
           family protein - Tetrahymena thermophila SB210
          Length = 551

 Score = 53.2 bits (122), Expect = 6e-06
 Identities = 28/62 (45%), Positives = 40/62 (64%), Gaps = 6/62 (9%)
 Frame = +2

Query: 257 EVTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSIPECQQQLPKA------KGGEEPL 418
           + TV  + GGMRG+KGL+ + S  D  +GI FRG +IP+ ++ LPKA      +  +EPL
Sbjct: 55  QYTVKQVIGGMRGMKGLMSDLSRCDPYQGIIFRGYTIPQLKEFLPKADPKAADQANQEPL 114

Query: 419 PE 424
           PE
Sbjct: 115 PE 116



 Score = 53.2 bits (122), Expect = 6e-06
 Identities = 29/72 (40%), Positives = 40/72 (55%), Gaps = 2/72 (2%)
 Frame = +1

Query: 427 LFWLLVTGDIPTEAQVKRCLKN--GRRGRIPAHVVXMLNXMPGKLHPMSQFSAAVTALNS 600
           +FWLL+TG +PT AQV   LK+    RG +    V  +  +P  LH M+  S A+  L  
Sbjct: 118 IFWLLMTGQLPTHAQVD-ALKHEWQNRGTVNQDCVNFILNLPKDLHSMTMLSMALLYLQK 176

Query: 601 ESKXAKAYSXGR 636
           +SK AK Y  G+
Sbjct: 177 DSKFAKLYDEGK 188



 Score = 33.9 bits (74), Expect = 3.7
 Identities = 13/31 (41%), Positives = 23/31 (74%)
 Frame = +3

Query: 162 QTNLKSILQEKIPKEQEKIREFRKKHGSTKV 254
           QTNLK ++ E IP++Q +++E ++K+G   V
Sbjct: 23  QTNLKKVIAEIIPQKQAELKEVKEKYGDKVV 53


>UniRef50_UPI0000DB6B6F Cluster: PREDICTED: similar to citrate
           synthase; n=1; Apis mellifera|Rep: PREDICTED: similar to
           citrate synthase - Apis mellifera
          Length = 795

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 24/56 (42%), Positives = 36/56 (64%)
 Frame = +2

Query: 257 EVTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSIPECQQQLPKAKGGEEPLPE 424
           +VTV+ +Y G+ G+  +V ETS  D+  GI++RGL+IPE    LP+   G+ P  E
Sbjct: 65  QVTVENIYQGLNGVNTIVRETSETDSKYGIKYRGLTIPEVITLLPRE--GKSPSAE 118



 Score = 37.9 bits (84), Expect = 0.23
 Identities = 16/39 (41%), Positives = 26/39 (66%)
 Frame = +3

Query: 144 RGLSAEQTNLKSILQEKIPKEQEKIREFRKKHGSTKVER 260
           RG+ +  T+LK  L EKIP   + +R FR++HGS+ + +
Sbjct: 27  RGVPSTSTDLKEALCEKIPIHYDLLRNFRQQHGSSVISQ 65


>UniRef50_Q8F887 Cluster: Citrate synthase; n=4; Leptospira|Rep:
           Citrate synthase - Leptospira interrogans
          Length = 426

 Score = 41.9 bits (94), Expect = 0.014
 Identities = 21/57 (36%), Positives = 34/57 (59%), Gaps = 1/57 (1%)
 Frame = +1

Query: 433 WLLVTGDIPTEAQVKR-CLKNGRRGRIPAHVVXMLNXMPGKLHPMSQFSAAVTALNS 600
           +LL+ G +PTE Q+K   LK  +   I   ++ + +  PGK HP++  S  VT+L+S
Sbjct: 87  YLLIYGKLPTEQQLKDFSLKLSKHSLIHEDMINLFDGFPGKGHPLAVLSVMVTSLSS 143


>UniRef50_A5KE63 Cluster: Citrate synthase, mitochondrial, putative;
           n=13; Plasmodium|Rep: Citrate synthase, mitochondrial,
           putative - Plasmodium vivax
          Length = 569

 Score = 37.5 bits (83), Expect = 0.30
 Identities = 22/72 (30%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
 Frame = +1

Query: 424 SLFWLLVTGDIPTEAQVKRCLKN--GRRGRIPAHVVXMLNXMPGKLHPMSQFSAAVTALN 597
           ++ W L+T +IP    +K   +    R  ++P+ V   ++ +P   HPMSQ  + V+ L 
Sbjct: 209 AMLWYLLTKEIPAADDLKLFSRELYCRAKKMPSFVFEFIDSIPTFTHPMSQLVSTVSFLE 268

Query: 598 SESKXAKAYSXG 633
           S S     YS G
Sbjct: 269 SLSLFKIKYSEG 280



 Score = 34.7 bits (76), Expect = 2.1
 Identities = 18/55 (32%), Positives = 32/55 (58%), Gaps = 1/55 (1%)
 Frame = +2

Query: 263 TVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSIPECQQQLPK-AKGGEEPLPE 424
           T + + GG+R    L+ +TS+L+  +GI FRG ++ +  +  PK  +  E P+ E
Sbjct: 154 TPNNVIGGLRNTITLITDTSILEKRKGILFRGRTVDKILKDFPKWDENCEYPMAE 208


>UniRef50_Q8NSL1 Cluster: 2-methylcitrate synthase 2; n=29;
           Bacteria|Rep: 2-methylcitrate synthase 2 -
           Corynebacterium glutamicum (Brevibacterium flavum)
          Length = 383

 Score = 35.9 bits (79), Expect = 0.92
 Identities = 17/60 (28%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
 Frame = +1

Query: 427 LFWLLVTGDIPTEAQVKRCLKNGRRGR-IPAHVVXMLNXMPGKLHPMSQFSAAVTALNSE 603
           +F+LL  G++PT  Q+    + GR  R + A ++ +++ +P + HPM     AV+ + ++
Sbjct: 52  VFYLLWHGELPTAQQLAEFNERGRSYRSLDAGLISLIHSLPKEAHPMDVMRTAVSYMGTK 111


>UniRef50_O75011 Cluster: Serine/threonine-protein kinase nak1; n=1;
           Schizosaccharomyces pombe|Rep: Serine/threonine-protein
           kinase nak1 - Schizosaccharomyces pombe (Fission yeast)
          Length = 652

 Score = 35.1 bits (77), Expect = 1.6
 Identities = 23/75 (30%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
 Frame = -1

Query: 339 SSASSTEVSQTRPLIPRMPPYIIST--VTSRL*WNHASFGIRGSSLVLWESFPGEYFLNS 166
           SS SST       L   +PP  I +  V      N+ S G+RG ++ L+  +PG      
Sbjct: 560 SSCSSTPKPFNSKLRAHLPPLSIGSPAVQPLANDNYDSLGVRGLNMELFNDYPGNMHNIK 619

Query: 165 SVQRLDLEVELSQSD 121
           SV  L++++ L + D
Sbjct: 620 SVLSLEIDIVLGEMD 634


>UniRef50_Q9LXS7 Cluster: Citrate synthase 1, peroxisomal precursor;
           n=11; cellular organisms|Rep: Citrate synthase 1,
           peroxisomal precursor - Arabidopsis thaliana (Mouse-ear
           cress)
          Length = 480

 Score = 34.7 bits (76), Expect = 2.1
 Identities = 16/64 (25%), Positives = 35/64 (54%), Gaps = 1/64 (1%)
 Frame = +1

Query: 409 RTTTRSLFWLLVTGDIPTEAQVKRC-LKNGRRGRIPAHVVXMLNXMPGKLHPMSQFSAAV 585
           ++T   + +LL+ G++P++ Q+        +   +P  V+ M+  MP  +HP+     A+
Sbjct: 129 KSTYTEVTYLLIYGNLPSQRQLADWEFAISQNSAVPQGVLDMIQSMPNDVHPVGALVTAM 188

Query: 586 TALN 597
           +AL+
Sbjct: 189 SALS 192


>UniRef50_Q7W5Q6 Cluster: 2-methylcitrate synthase; n=122;
           Bacteria|Rep: 2-methylcitrate synthase - Bordetella
           parapertussis
          Length = 400

 Score = 34.3 bits (75), Expect = 2.8
 Identities = 19/54 (35%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
 Frame = +1

Query: 436 LLVTGDIPTEAQVKRCLKNGRRGR-IPAHVVXMLNXMPGKLHPMSQFSAAVTAL 594
           LLV G +P +A++K   +  R  R +PA +  +L  +P   HPM     AV+ L
Sbjct: 75  LLVHGKLPNKAELKAYKEKLRALRGLPAQLQNVLECLPASSHPMDVMRTAVSVL 128


>UniRef50_A6T3T1 Cluster: 2-methylcitrate synthase; n=60;
           Bacteria|Rep: 2-methylcitrate synthase -
           Janthinobacterium sp. (strain Marseille) (Minibacterium
           massiliensis)
          Length = 387

 Score = 34.3 bits (75), Expect = 2.8
 Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
 Frame = +1

Query: 436 LLVTGDIPTEAQVKRC-LKNGRRGRIPAHVVXMLNXMPGKLHPMSQFSAAVTAL 594
           LLV G +PT A++K   +K      +PA+V   L  +P   HPM      V+AL
Sbjct: 62  LLVHGKLPTAAELKAYKIKLKELRGLPANVKAALEWLPAASHPMDVMRTGVSAL 115


>UniRef50_A7S7M5 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 1041

 Score = 34.3 bits (75), Expect = 2.8
 Identities = 25/86 (29%), Positives = 41/86 (47%)
 Frame = +3

Query: 3   ARDRSRASCRDLCGSLRSAALKMALFRITSSRLVELQKACPTATVLLRGLSAEQTNLKSI 182
           ARDR R   RD C S RS++ +  L  + SS    L      AT +  G       ++  
Sbjct: 554 ARDRPRERSRDSCSSARSSSRERPLSAMLSSSWDTLPFGTTEATRMREG------RIRES 607

Query: 183 LQEKIPKEQEKIREFRKKHGSTKVER 260
           L+E+  +EQ +++E +++    K  R
Sbjct: 608 LKERRAREQAELKEEQQRQKKLKSMR 633


>UniRef50_Q1E3Z8 Cluster: Putative uncharacterized protein; n=1;
           Coccidioides immitis|Rep: Putative uncharacterized
           protein - Coccidioides immitis
          Length = 1155

 Score = 34.3 bits (75), Expect = 2.8
 Identities = 20/46 (43%), Positives = 26/46 (56%)
 Frame = -3

Query: 307 QTFDSTHATVHHINCDLSTLVEPCFFRNSRIFSCSLGIFSWRILFK 170
           QTF  T  ++  I  D   L EP   RN R+FS  +G FS R+L+K
Sbjct: 550 QTFSETQTSIA-IPEDAVFLNEPDMKRNGRVFSDGVGTFSPRLLYK 594


>UniRef50_Q9PKT4 Cluster: Putative uncharacterized protein; n=3;
           Chlamydia|Rep: Putative uncharacterized protein -
           Chlamydia muridarum
          Length = 153

 Score = 33.5 bits (73), Expect = 4.9
 Identities = 28/98 (28%), Positives = 38/98 (38%), Gaps = 1/98 (1%)
 Frame = -1

Query: 381 CW-HSGMDRPRKRIPSSASSTEVSQTRPLIPRMPPYIISTVTSRL*WNHASFGIRGSSLV 205
           CW      R R  IPSS SS +V   R L  +   Y+I      +         RG  + 
Sbjct: 58  CWLFRRFLRSRGHIPSSNSSIKVLDRRVLPSKTSIYVIKVANKTI-----VIAERGEHVT 112

Query: 204 LWESFPGEYFLNSSVQRLDLEVELSQSDMLSAILRVLK 91
           L   FP    LN  +Q+   +    + +MLS  L   K
Sbjct: 113 LLSEFPPNTDLNELMQQDQKKTPTPRREMLSGFLNQFK 150


>UniRef50_Q6LFK6 Cluster: Putative uncharacterized protein; n=2;
           Plasmodium|Rep: Putative uncharacterized protein -
           Plasmodium falciparum (isolate 3D7)
          Length = 1063

 Score = 33.1 bits (72), Expect = 6.5
 Identities = 11/27 (40%), Positives = 20/27 (74%)
 Frame = +3

Query: 366 SLSANSNCPRLRVEKNHYPKSFLASRH 446
           ++S + +CP+  ++KNH+ KSFL+  H
Sbjct: 423 AMSISYSCPKENIKKNHFLKSFLSGEH 449


>UniRef50_Q823X4 Cluster: Polymorphic outer membrane protein G
           family protein; n=3; Chlamydophila|Rep: Polymorphic
           outer membrane protein G family protein - Chlamydophila
           caviae
          Length = 868

 Score = 32.7 bits (71), Expect = 8.6
 Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 1/111 (0%)
 Frame = -3

Query: 355 TETDSFIGIQHRGFPNQTFDSTHATVHHINCDLSTLVEPCFFRNSRIFSCSLGIFSWRIL 176
           T TD+F GI +  FP +T DS   T + ++ D+  +++     N R  SC        ++
Sbjct: 32  TATDNFDGINNAAFPTKTSDSDEGTNYILSNDI--VIQNVAATNPRNSSCFKNT-KGNLI 88

Query: 175 FKFVCSALRPRSRTVAV-GHAFCNSTSLEDVILNRAIFKAAERKLPHKSRQ 26
           F     +L   + T AV G A  NS+   +  L+ + F   +   P  SR+
Sbjct: 89  FNGNNRSLTFNNITTAVEGKAILNSS---ETFLSMSCFSKLQFLEPVSSRK 136


>UniRef50_A2F9Q9 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 1936

 Score = 32.7 bits (71), Expect = 8.6
 Identities = 16/43 (37%), Positives = 27/43 (62%)
 Frame = +3

Query: 177 SILQEKIPKEQEKIREFRKKHGSTKVERSQLI*CTVACVESKV 305
           + ++EKIPK+Q+K  E  +K    K+E S++   T+  VE K+
Sbjct: 590 TFIEEKIPKKQQKKPEILQKQQEEKLEISKMKQETIEFVEEKI 632


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 654,272,926
Number of Sequences: 1657284
Number of extensions: 12527829
Number of successful extensions: 38327
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 36825
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 38309
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 53305790091
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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