Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= NV060443.seq
(679 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
DQ314875-1|ABC40734.1| 606|Homo sapiens mitogen-activated prote... 156 6e-38
BT019654-1|AAV38460.1| 579|Homo sapiens mitogen-activated prote... 156 6e-38
BC017715-1|AAH17715.1| 579|Homo sapiens mitogen-activated prote... 156 6e-38
AL121964-4|CAI19611.1| 579|Homo sapiens mitogen-activated prote... 156 6e-38
AL121964-3|CAI19612.1| 606|Homo sapiens mitogen-activated prote... 156 6e-38
AL121964-2|CAI19609.1| 491|Homo sapiens mitogen-activated prote... 156 6e-38
AL121964-1|CAI19610.1| 518|Homo sapiens mitogen-activated prote... 156 6e-38
AL121837-4|CAI23533.1| 579|Homo sapiens mitogen-activated prote... 156 6e-38
AL121837-3|CAI23532.1| 606|Homo sapiens mitogen-activated prote... 156 6e-38
AL121837-2|CAI23531.1| 491|Homo sapiens mitogen-activated prote... 156 6e-38
AL121837-1|CAI23530.1| 518|Homo sapiens mitogen-activated prote... 156 6e-38
AF218074-1|AAF27652.1| 491|Homo sapiens TGF beta-activated kina... 156 6e-38
AB009358-1|BAA25027.2| 518|Homo sapiens TGF-beta activated kina... 156 6e-38
AB009357-1|BAA25026.1| 606|Homo sapiens TGF-beta activated kina... 156 6e-38
AB009356-1|BAA25025.1| 579|Homo sapiens TGF-beta activated kina... 156 6e-38
BT019655-1|AAV38461.1| 606|Homo sapiens mitogen-activated prote... 156 8e-38
Z48615-1|CAA88531.1| 953|Homo sapiens serine/threonine kinase w... 65 2e-10
X90846-1|CAA62351.1| 954|Homo sapiens mixed lineage kinase 2 pr... 65 2e-10
BC001401-1|AAH01401.1| 455|Homo sapiens sterile alpha motif and... 63 1e-09
AF480462-1|AAL85892.1| 455|Homo sapiens mixed lineage kinase-re... 63 1e-09
AF480461-1|AAL85891.1| 800|Homo sapiens mixed lineage kinase-re... 63 1e-09
AF465843-1|AAO33376.1| 312|Homo sapiens cervical cancer suppres... 63 1e-09
AF325454-1|AAK11615.1| 455|Homo sapiens mixed lineage kinase pr... 63 1e-09
AF251441-1|AAF65822.1| 800|Homo sapiens sterile-alpha motif and... 63 1e-09
AF238255-1|AAF63490.1| 800|Homo sapiens mixed lineage kinase ZA... 63 1e-09
AC013461-1|AAX93067.1| 400|Homo sapiens unknown protein. 63 1e-09
AB208974-1|BAD92211.1| 845|Homo sapiens Plaucible mixed-lineage... 63 1e-09
AB049734-1|BAB16445.1| 455|Homo sapiens MLTK-beta protein. 63 1e-09
AB049733-1|BAB16444.1| 800|Homo sapiens MLTK-alpha protein. 63 1e-09
AB030034-1|BAB12040.1| 800|Homo sapiens plaucible mixed-lineage... 63 1e-09
S65186-1|AAB28072.2| 620|Homo sapiens EMT protein. 61 4e-09
L10717-1|AAA36748.1| 620|Homo sapiens tyrosine kinase protein. 61 4e-09
D13720-1|BAA02873.1| 620|Homo sapiens ITK protein. 61 4e-09
BC109078-1|AAI09079.1| 620|Homo sapiens IL2-inducible T-cell ki... 61 4e-09
BC109077-1|AAI09078.1| 620|Homo sapiens IL2-inducible T-cell ki... 61 4e-09
U22322-1|AAC50116.1| 505|Homo sapiens Rak protein. 58 3e-08
U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase ... 58 3e-08
BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase prot... 58 3e-08
AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase prot... 58 3e-08
AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase prot... 58 3e-08
AB001872-1|BAA24817.1| 966|Homo sapiens leucine zipper bearing ... 58 3e-08
L76191-1|AAC41949.1| 712|Homo sapiens interleukin-1 receptor-as... 58 4e-08
DQ054788-1|AAY88246.1| 633|Homo sapiens interleukin-1 receptor ... 58 4e-08
BC054000-1|AAH54000.1| 693|Homo sapiens IRAK1 protein protein. 58 4e-08
BC014963-1|AAH14963.1| 633|Homo sapiens interleukin-1 receptor-... 58 4e-08
AF346607-1|AAK62888.1| 682|Homo sapiens interleukin-1 receptor ... 58 4e-08
AF030876-1|AAC08756.1| 712|Homo sapiens Interleukin 1 receptor-... 58 4e-08
D29767-1|BAA06171.1| 631|Homo sapiens Tec protein-tyrosine kina... 57 5e-08
BC101713-1|AAI01714.1| 631|Homo sapiens tec protein tyrosine ki... 57 5e-08
BC101711-1|AAI01712.1| 631|Homo sapiens tec protein tyrosine ki... 57 5e-08
U34379-1|AAB60412.1| 527|Homo sapiens tyrosine kinase protein. 57 7e-08
L27071-1|AAA74557.1| 527|Homo sapiens tyrosine kinase protein. 56 9e-08
U07747-1|AAA19647.1| 847|Homo sapiens serine/threonine protein ... 55 3e-07
L32976-1|AAA59859.1| 847|Homo sapiens protein kinase protein. 55 3e-07
BC064543-1|AAH64543.1| 847|Homo sapiens mitogen-activated prote... 55 3e-07
BC011263-1|AAH11263.1| 847|Homo sapiens mitogen-activated prote... 55 3e-07
AL133380-4|CAI23046.1| 1036|Homo sapiens mixed lineage kinase 4 ... 55 3e-07
AL133380-3|CAI23045.1| 570|Homo sapiens mixed lineage kinase 4 ... 55 3e-07
AK222781-1|BAD96501.1| 847|Homo sapiens mitogen-activated prote... 55 3e-07
AJ311798-1|CAC84640.1| 1036|Homo sapiens mixed lineage kinase 4b... 55 3e-07
AJ311797-1|CAC84639.1| 570|Homo sapiens mixed lineage kinase 4a... 55 3e-07
AB209655-1|BAD92892.1| 310|Homo sapiens mitogen-activated prote... 55 3e-07
L40636-1|AAB08520.1| 984|Homo sapiens protein tyrosine kinase p... 54 4e-07
BC111744-1|AAI11745.1| 984|Homo sapiens EPH receptor B1 protein. 54 4e-07
AF037332-1|AAD02031.1| 973|Homo sapiens Eph-like receptor tyros... 54 4e-07
AF037331-1|AAD02030.1| 984|Homo sapiens Eph-like receptor tyros... 54 4e-07
U07358-1|AAA67343.1| 859|Homo sapiens serine/threonine protein ... 54 5e-07
BC050050-1|AAH50050.1| 567|Homo sapiens MAP3K12 protein protein. 54 5e-07
AF283475-1|AAL67158.1| 859|Homo sapiens zipper protein kinase p... 54 5e-07
X58957-1|CAA41728.1| 659|Homo sapiens agammaglobulinaemia tyros... 54 6e-07
U78027-4|AAB64205.1| 659|Homo sapiens Bruton's tyrosine kinase ... 54 6e-07
U13433-1|AAC51347.1| 657|Homo sapiens Bruton's agammaglobulinem... 54 6e-07
U10087-1|AAB60639.1| 659|Homo sapiens Bruton agammaglobulinemia... 54 6e-07
L31572-1|AAA61479.1| 659|Homo sapiens Bruton agammaglobulinemia... 54 6e-07
BC109080-1|AAI09081.1| 659|Homo sapiens Bruton agammaglobulinem... 54 6e-07
BC109079-1|AAI09080.1| 659|Homo sapiens Bruton agammaglobulinem... 54 6e-07
AM051278-1|CAJ19684.1| 197|Homo sapiens dominant-negative kinas... 54 6e-07
AM051277-1|CAJ19683.1| 172|Homo sapiens dominant-negative kinas... 54 6e-07
AM051276-1|CAJ19682.1| 319|Homo sapiens dominant-negative kinas... 54 6e-07
AL035422-3|CAB55876.1| 659|Homo sapiens Bruton agammaglobulinem... 54 6e-07
X83107-1|CAA58169.1| 675|Homo sapiens bmx protein. 53 8e-07
BC016652-1|AAH16652.1| 675|Homo sapiens BMX non-receptor tyrosi... 53 8e-07
AF045459-1|AAC08966.1| 697|Homo sapiens Etk/Bmx cytosolic tyros... 53 8e-07
BC133706-1|AAI33707.1| 1104|Homo sapiens MAP3K9 protein protein. 53 1e-06
BC111407-1|AAI11408.1| 1103|Homo sapiens MAP3K9 protein protein. 53 1e-06
AY327900-1|AAQ23054.1| 1104|Homo sapiens mixed-lineage protein k... 53 1e-06
AF251442-1|AAG44591.1| 1066|Homo sapiens mixed lineage kinase ML... 53 1e-06
AF042838-1|AAC97073.1| 1495|Homo sapiens MEK kinase 1 protein. 52 1e-06
BX538196-1|CAD98063.1| 109|Homo sapiens hypothetical protein pr... 52 2e-06
X75208-1|CAA53021.1| 998|Homo sapiens protein tyrosine kinase-r... 51 3e-06
BC111965-1|AAI11966.1| 863|Homo sapiens AP2 associated kinase 1... 51 3e-06
BC104842-1|AAI04843.1| 863|Homo sapiens AP2 associated kinase 1... 51 3e-06
BC052968-1|AAH52968.1| 998|Homo sapiens EPH receptor B3 protein. 51 3e-06
BC002695-1|AAH02695.1| 474|Homo sapiens AAK1 protein protein. 51 3e-06
AC079121-1|AAY14931.1| 769|Homo sapiens unknown protein. 51 3e-06
AB028971-1|BAA83000.2| 897|Homo sapiens KIAA1048 protein protein. 51 3e-06
X03484-1|CAA27204.1| 648|Homo sapiens protein ( Human mRNA for ... 51 4e-06
L00212-1|AAA60247.1| 421|Homo sapiens RAF1 protein. 51 4e-06
BC018119-1|AAH18119.1| 648|Homo sapiens v-raf-1 murine leukemia... 51 4e-06
AY271661-1|AAP03432.1| 648|Homo sapiens v-raf-1 murine leukemia... 51 4e-06
Z25428-1|CAA80915.1| 111|Homo sapiens protein-serine/threonine ... 50 6e-06
X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRN... 50 6e-06
U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene tyrosine-p... 50 6e-06
U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene tyrosine-p... 50 6e-06
M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein. 50 6e-06
DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine le... 50 6e-06
BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine le... 50 6e-06
AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine l... 50 6e-06
AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine le... 50 6e-06
AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine le... 50 6e-06
AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine le... 50 6e-06
X52192-1|CAA36438.1| 822|Homo sapiens c-fes protein. 50 8e-06
X06292-1|CAA29619.1| 822|Homo sapiens NCP92 protein. 50 8e-06
BC036021-1|AAH36021.1| 662|Homo sapiens BMP2 inducible kinase p... 50 8e-06
BC035357-1|AAH35357.1| 822|Homo sapiens feline sarcoma oncogene... 50 8e-06
AY513657-1|AAS82869.1| 752|Homo sapiens proto-oncogene c-fes va... 50 8e-06
AY513656-1|AAS82868.1| 764|Homo sapiens proto-oncogene c-fes va... 50 8e-06
AY513654-1|AAS82866.1| 694|Homo sapiens proto-oncogene c-fes va... 50 8e-06
AL137661-1|CAB70863.1| 661|Homo sapiens hypothetical protein pr... 50 8e-06
AL121829-14|CAC15526.1| 488|Homo sapiens protein ( ne kinase, t... 50 8e-06
AC098818-1|AAY40926.1| 662|Homo sapiens unknown protein. 50 8e-06
Z84466-8|CAI42468.1| 606|Homo sapiens v-raf murine sarcoma 3611... 50 1e-05
X04790-1|CAA28476.1| 606|Homo sapiens protein ( Human mRNA for ... 50 1e-05
U01337-1|AAB03517.1| 606|Homo sapiens Ser/Thr protein kinase pr... 50 1e-05
M13829-1|AAB08754.1| 298|Homo sapiens raf related protein protein. 50 1e-05
L41939-1|AAA99310.1| 987|Homo sapiens protein-tyrosine kinase p... 50 1e-05
L36643-1|AAA74244.1| 970|Homo sapiens receptor protein-tyrosine... 50 1e-05
L36642-1|AAA74243.1| 998|Homo sapiens receptor protein-tyrosine... 50 1e-05
L24038-1|AAA65219.1| 606|Homo sapiens ARAF1 protein. 50 1e-05
D37827-1|BAA07073.1| 478|Homo sapiens large erk/cek5 tyrosine k... 50 1e-05
D31661-1|BAA06506.1| 981|Homo sapiens tyrosine kinase precursor... 50 1e-05
BT019864-1|AAV38667.1| 606|Homo sapiens v-raf murine sarcoma 36... 50 1e-05
BC126151-1|AAI26152.1| 998|Homo sapiens EPH receptor A7 protein. 50 1e-05
BC126125-1|AAI26126.1| 998|Homo sapiens EPH receptor A7 protein. 50 1e-05
BC013316-1|AAH13316.1| 460|Homo sapiens interleukin-1 receptor-... 50 1e-05
BC007514-1|AAH07514.1| 609|Homo sapiens ARAF protein protein. 50 1e-05
BC002466-1|AAH02466.1| 606|Homo sapiens v-raf murine sarcoma 36... 50 1e-05
AY730682-1|AAX22228.1| 460|Homo sapiens interleukin-1 receptor ... 50 1e-05
AY340967-1|AAR02363.1| 336|Homo sapiens interleukin-1 receptor-... 50 1e-05
AY340966-1|AAR02362.1| 336|Homo sapiens interleukin-1 receptor-... 50 1e-05
AY340965-1|AAR02361.1| 336|Homo sapiens interleukin-1 receptor-... 50 1e-05
AY340964-1|AAR02360.1| 336|Homo sapiens interleukin-1 receptor-... 50 1e-05
AY340963-1|AAR02359.1| 460|Homo sapiens interleukin-1 receptor-... 50 1e-05
AY340962-1|AAR02358.1| 460|Homo sapiens interleukin-1 receptor-... 50 1e-05
AY283670-1|AAP57089.1| 292|Homo sapiens interleukin-1 receptor ... 50 1e-05
AY186092-1|AAN75440.1| 460|Homo sapiens interleukin-1 receptor-... 50 1e-05
AL591036-1|CAH73650.1| 998|Homo sapiens EPH receptor A7 protein. 50 1e-05
AL512444-4|CAI16429.1| 1055|Homo sapiens EPH receptor B2 protein. 50 1e-05
AL512444-3|CAI16430.2| 986|Homo sapiens EPH receptor B2 protein. 50 1e-05
AL512444-2|CAI16428.1| 987|Homo sapiens EPH receptor B2 protein. 50 1e-05
AL512444-1|CAI16427.1| 946|Homo sapiens EPH receptor B2 protein. 50 1e-05
AL354857-1|CAH72780.1| 998|Homo sapiens EPH receptor A7 protein. 50 1e-05
AL158086-8|CAI22898.1| 1055|Homo sapiens EPH receptor B2 protein. 50 1e-05
AL158086-7|CAI22899.2| 986|Homo sapiens EPH receptor B2 protein. 50 1e-05
AL158086-6|CAI22897.1| 987|Homo sapiens EPH receptor B2 protein. 50 1e-05
AL121966-2|CAI19722.1| 998|Homo sapiens EPH receptor A7 protein. 50 1e-05
AL035704-4|CAI22646.1| 1055|Homo sapiens EPH receptor B2 protein. 50 1e-05
AL035704-3|CAI22647.2| 986|Homo sapiens EPH receptor B2 protein. 50 1e-05
AL035704-2|CAI22645.1| 987|Homo sapiens EPH receptor B2 protein. 50 1e-05
AL035704-1|CAI22644.1| 946|Homo sapiens EPH receptor B2 protein. 50 1e-05
AK027301-1|BAD12234.1| 277|Homo sapiens protein ( Homo sapiens ... 50 1e-05
AK000528-1|BAA91232.1| 460|Homo sapiens protein ( Homo sapiens ... 50 1e-05
AF445802-1|AAM15772.1| 460|Homo sapiens interleukin-1 receptor ... 50 1e-05
AF155118-1|AAD42884.1| 460|Homo sapiens putative protein kinase... 50 1e-05
AF025304-1|AAB94602.1| 1055|Homo sapiens protein-tyrosine kinase... 50 1e-05
AB210018-1|BAE06100.1| 1004|Homo sapiens EPHB2 variant protein p... 50 1e-05
AB209269-1|BAD92506.1| 1000|Homo sapiens ephrin receptor EphA7 v... 50 1e-05
J03358-1|AAA61190.1| 822|Homo sapiens FER protein. 49 1e-05
DQ822519-1|ABG46944.1| 835|Homo sapiens TNNI3 interacting kinas... 49 1e-05
BX640903-1|CAE45949.1| 714|Homo sapiens hypothetical protein pr... 49 1e-05
BX470253-1|CAI16293.1| 835|Homo sapiens TNNI3 interacting kinas... 49 1e-05
BC117262-1|AAI17263.1| 835|Homo sapiens TNNI3 interacting kinas... 49 1e-05
BC113539-1|AAI13540.1| 835|Homo sapiens TNNI3 interacting kinas... 49 1e-05
BC032865-1|AAH32865.1| 843|Homo sapiens TNNI3K protein protein. 49 1e-05
AY303691-1|AAP72030.1| 835|Homo sapiens cardiac ankyrin repeat ... 49 1e-05
AF116826-1|AAD29632.1| 835|Homo sapiens putative protein-tyrosi... 49 1e-05
AB208941-1|BAD92178.1| 941|Homo sapiens TNNI3 interacting kinas... 49 1e-05
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 49 2e-05
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 49 2e-05
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 49 2e-05
U50648-1|AAC50768.1| 551|Homo sapiens interferon-inducible RNA-... 48 3e-05
M95712-1|AAA35609.2| 766|Homo sapiens B-raf protein protein. 48 3e-05
M85294-1|AAA18253.1| 551|Homo sapiens P1/eIF-2a protein kinase ... 48 3e-05
M35663-1|AAA36409.1| 551|Homo sapiens protein ( Human p68 kinas... 48 3e-05
M21001-1|AAA96495.1| 328|Homo sapiens B-raf protein protein. 48 3e-05
BC112079-1|AAI12080.1| 766|Homo sapiens v-raf murine sarcoma vi... 48 3e-05
BC101757-1|AAI01758.1| 766|Homo sapiens v-raf murine sarcoma vi... 48 3e-05
BC101475-1|AAI01476.1| 551|Homo sapiens eukaryotic translation ... 48 3e-05
BC094862-1|AAH94862.1| 393|Homo sapiens WNK1 protein protein. 48 3e-05
BC093676-1|AAH93676.1| 551|Homo sapiens eukaryotic translation ... 48 3e-05
BC057805-1|AAH57805.1| 513|Homo sapiens EIF2AK2 protein protein. 48 3e-05
BC040851-1|AAH40851.1| 513|Homo sapiens EIF2AK2 protein protein. 48 3e-05
BC021121-1|AAH21121.1| 393|Homo sapiens WNK1 protein protein. 48 3e-05
BC006524-1|AAH06524.1| 630|Homo sapiens eukaryotic translation ... 48 3e-05
AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion prote... 48 3e-05
AY302136-1|AAP57628.1| 510|Homo sapiens interferon-inducible do... 48 3e-05
AY228338-1|AAO38055.1| 551|Homo sapiens protein kinase, interfe... 48 3e-05
AL583839-7|CAO03350.1| 2219|Homo sapiens WNK lysine deficient pr... 48 3e-05
AL583839-6|CAI12344.3| 2297|Homo sapiens WNK lysine deficient pr... 48 3e-05
AL390760-3|CAO03647.1| 2219|Homo sapiens WNK lysine deficient pr... 48 3e-05
AL390760-2|CAO03646.1| 790|Homo sapiens WNK lysine deficient pr... 48 3e-05
AL390760-1|CAH73069.3| 2297|Homo sapiens WNK lysine deficient pr... 48 3e-05
AL354991-3|CAO03639.1| 2219|Homo sapiens WNK lysine deficient pr... 48 3e-05
AL354991-2|CAI14449.3| 2297|Homo sapiens WNK lysine deficient pr... 48 3e-05
AK075192-1|BAC11461.1| 630|Homo sapiens protein ( Homo sapiens ... 48 3e-05
AJ296290-1|CAC15059.1| 2382|Homo sapiens putative protein kinase... 48 3e-05
AJ242724-1|CAB44308.5| 2297|Homo sapiens putative mitogen-activa... 48 3e-05
AF255050-1|AAF70289.1| 629|Homo sapiens heme-regulated eukaryot... 48 3e-05
AF183414-1|AAG09683.1| 630|Homo sapiens hemin-sensitive initiat... 48 3e-05
AF181071-1|AAF18391.1| 630|Homo sapiens heme-regulated initiati... 48 3e-05
AF167472-1|AAF13156.1| 551|Homo sapiens double stranded RNA act... 48 3e-05
AF147094-1|AAF66736.1| 629|Homo sapiens heme-regulated initiati... 48 3e-05
AF100784-1|AAP97223.1| 630|Homo sapiens hemin-sensitive initita... 48 3e-05
AF061944-1|AAF31483.1| 670|Homo sapiens kinase deficient protei... 48 3e-05
AC007899-1|AAY24317.1| 551|Homo sapiens unknown protein. 48 3e-05
AC006344-3|AAD43193.1| 651|Homo sapiens WUGSC:H_DJ0726N20.3 pro... 48 3e-05
AC005995-1|AAS00388.1| 386|Homo sapiens unknown protein. 48 3e-05
AB209642-1|BAD92879.1| 949|Homo sapiens Proto-oncogene tyrosine... 48 3e-05
AB051547-1|BAB21851.2| 2219|Homo sapiens KIAA1760 protein protein. 48 3e-05
AB044546-1|BAB18648.1| 779|Homo sapiens mitogen-activated prote... 48 3e-05
AB037790-1|BAA92607.1| 653|Homo sapiens KIAA1369 protein protein. 48 3e-05
AB002342-1|BAA20802.2| 2066|Homo sapiens KIAA0344 protein. 48 3e-05
Z84469-2|CAI42732.1| 1790|Homo sapiens WNK lysine deficient prot... 48 4e-05
Z84469-1|CAI42733.1| 1743|Homo sapiens WNK lysine deficient prot... 48 4e-05
U63333-1|AAB05809.1| 433|Homo sapiens serine/threonine protein ... 48 4e-05
U07695-1|AAA20598.1| 987|Homo sapiens tyrosine kinase protein. 48 4e-05
D88435-1|BAA22623.1| 1311|Homo sapiens HsGAK protein. 48 4e-05
BC085005-1|AAH85005.1| 1232|Homo sapiens GAK protein protein. 48 4e-05
BC052804-1|AAH52804.1| 987|Homo sapiens EPH receptor B4 protein. 48 4e-05
BC019334-1|AAH19334.1| 433|Homo sapiens serine/threonine kinase... 48 4e-05
BC007981-1|AAH07981.1| 433|Homo sapiens serine/threonine kinase... 48 4e-05
BC004264-1|AAH04264.1| 845|Homo sapiens EPHB4 protein protein. 48 4e-05
AY352048-1|AAR89465.1| 1800|Homo sapiens putative protein kinase... 48 4e-05
AY082340-1|AAL99253.1| 1800|Homo sapiens putative protein kinase... 48 4e-05
AY056048-1|AAL14195.1| 935|Homo sapiens receptor protein tyrosi... 48 4e-05
AY056047-1|AAL14194.1| 987|Homo sapiens receptor protein tyrosi... 48 4e-05
AL591766-2|CAI40707.1| 1790|Homo sapiens WNK lysine deficient pr... 48 4e-05
AL591766-1|CAI40708.1| 1743|Homo sapiens WNK lysine deficient pr... 48 4e-05
AL049793-2|CAI43128.1| 1790|Homo sapiens WNK lysine deficient pr... 48 4e-05
AL049793-1|CAI43129.1| 1743|Homo sapiens WNK lysine deficient pr... 48 4e-05
AJ409088-1|CAC32455.2| 1743|Homo sapiens protein kinase WNK3 pro... 48 4e-05
AF312032-8|AAK21010.1| 987|Homo sapiens ephrin type-B receptor ... 48 4e-05
AF217978-1|AAG17221.1| 433|Homo sapiens unknown protein. 48 4e-05
AF055327-1|AAC15742.1| 433|Homo sapiens Peutz-Jeghers syndrome ... 48 4e-05
AF035625-1|AAC39527.1| 433|Homo sapiens serine threonine kinase... 48 4e-05
AF032986-1|AAB97833.1| 433|Homo sapiens serine threonine kinase... 48 4e-05
AB209644-1|BAD92881.1| 986|Homo sapiens ephrin receptor EphB4 p... 48 4e-05
AB209553-1|BAD92790.1| 337|Homo sapiens serine/threonine protei... 48 4e-05
AB208854-1|BAD92091.1| 1196|Homo sapiens Cyclin G-associated kin... 48 4e-05
X74765-1|CAB58562.1| 450|Homo sapiens protein tyrosine kinase p... 47 5e-05
X60114-1|CAA42713.1| 450|Homo sapiens put. cytoplasmic tyrosine... 47 5e-05
X59932-1|CAA42556.1| 450|Homo sapiens c-src-kinase protein. 47 5e-05
DQ075211-1|AAY57329.1| 450|Homo sapiens c-src tyrosine kinase p... 47 5e-05
CR541960-1|CAG46758.1| 450|Homo sapiens CSK protein. 47 5e-05
BC106073-1|AAI06074.1| 450|Homo sapiens c-src tyrosine kinase p... 47 5e-05
BC104875-1|AAI04876.1| 450|Homo sapiens c-src tyrosine kinase p... 47 5e-05
BC104847-1|AAI04848.1| 450|Homo sapiens c-src tyrosine kinase p... 47 5e-05
AY603755-1|AAT80901.1| 3094|Homo sapiens striated muscle prefere... 47 5e-05
AK223626-1|BAD97346.1| 449|Homo sapiens c-src tyrosine kinase v... 47 5e-05
AB037718-1|BAA92535.1| 2242|Homo sapiens KIAA1297 protein protein. 47 5e-05
M35296-1|AAA35553.1| 1182|Homo sapiens protein ( Human tyrosine ... 47 7e-05
DQ009672-1|AAY16984.1| 1182|Homo sapiens v-abl Abelson murine le... 47 7e-05
BX538317-1|CAD98092.1| 1092|Homo sapiens hypothetical protein pr... 47 7e-05
BC111726-1|AAI11727.1| 656|Homo sapiens MAP3K13 protein protein. 47 7e-05
BC065912-1|AAH65912.1| 1167|Homo sapiens ABL2 protein protein. 47 7e-05
AL512326-6|CAI13570.1| 1182|Homo sapiens v-abl Abelson murine le... 47 7e-05
AL512326-2|CAI13566.1| 1064|Homo sapiens v-abl Abelson murine le... 47 7e-05
AL359179-2|CAI15585.1| 1182|Homo sapiens v-abl Abelson murine le... 47 7e-05
AL359179-1|CAI15584.1| 1064|Homo sapiens v-abl Abelson murine le... 47 7e-05
AL139132-5|CAH70925.1| 1182|Homo sapiens v-abl Abelson murine le... 47 7e-05
AL139132-1|CAH70921.1| 1064|Homo sapiens v-abl Abelson murine le... 47 7e-05
U63721-3|AAC13886.1| 633|Homo sapiens LIM-kinase protein. 46 9e-05
U63721-2|AAC13885.1| 647|Homo sapiens LIM-kinase protein. 46 9e-05
U62293-2|AAB17546.1| 633|Homo sapiens alternatively spliced LIM... 46 9e-05
U62293-1|AAB17545.1| 647|Homo sapiens LIM-kinase1 protein. 46 9e-05
M34182-1|AAC41690.1| 360|Homo sapiens protein kinase A gamma-su... 46 9e-05
EF644172-1|ABR45718.1| 433|Homo sapiens polarization-related pr... 46 9e-05
D26309-1|BAA05371.1| 647|Homo sapiens LIM kinase protein. 46 9e-05
DQ667175-1|ABG25920.1| 351|Homo sapiens protein kinase, cAMP-de... 46 9e-05
BC039888-1|AAH39888.1| 351|Homo sapiens protein kinase, cAMP-de... 46 9e-05
BC033085-1|AAH33085.1| 542|Homo sapiens TESK2 protein protein. 46 9e-05
BC002655-1|AAH02655.1| 275|Homo sapiens CCRK protein protein. 46 9e-05
AY904367-1|AAW82349.1| 243|Homo sapiens cell cycle-related kina... 46 9e-05
AL451136-3|CAI13093.1| 571|Homo sapiens testis-specific kinase ... 46 9e-05
AL451136-2|CAI13092.1| 542|Homo sapiens testis-specific kinase ... 46 9e-05
AL359540-13|CAI21724.1| 571|Homo sapiens testis-specific kinase... 46 9e-05
AL359540-12|CAI21723.1| 542|Homo sapiens testis-specific kinase... 46 9e-05
AL353572-5|CAH72843.1| 325|Homo sapiens cell cycle related kina... 46 9e-05
AL353572-4|CAM17657.1| 346|Homo sapiens cell cycle related kina... 46 9e-05
AL353572-3|CAM17658.1| 338|Homo sapiens cell cycle related kina... 46 9e-05
AL162730-1|CAH71828.1| 351|Homo sapiens protein kinase, cAMP-de... 46 9e-05
AJ132545-1|CAB41970.1| 555|Homo sapiens protein kinase protein. 46 9e-05
AJ001597-1|CAA04863.1| 351|Homo sapiens cAMP-dependent protein ... 46 9e-05
AF547664-1|AAN28684.1| 346|Homo sapiens cell cycle related kina... 46 9e-05
AF113130-1|AAF43778.1| 452|Homo sapiens cyclin-dependent protei... 46 9e-05
AF035013-1|AAC98920.1| 452|Homo sapiens cell cycle related kina... 46 9e-05
AC005057-3|AAS07438.1| 596|Homo sapiens unknown protein. 46 9e-05
AB057597-1|BAB62909.1| 571|Homo sapiens testicular protein kina... 46 9e-05
X75346-1|CAA53094.1| 396|Homo sapiens MAP kinase activated prot... 46 1e-04
U77129-1|AAB48435.1| 846|Homo sapiens KHS1 protein. 46 1e-04
U12779-1|AAA20851.1| 370|Homo sapiens MAP kinase activated prot... 46 1e-04
D50863-1|BAA09459.1| 626|Homo sapiens TESK1 protein. 46 1e-04
BC109097-1|AAI09098.2| 795|Homo sapiens MLCK protein protein. 46 1e-04
BC067130-1|AAH67130.1| 626|Homo sapiens TESK1 protein protein. 46 1e-04
BC052584-1|AAH52584.1| 400|Homo sapiens mitogen-activated prote... 46 1e-04
BC038448-1|AAH38448.1| 626|Homo sapiens TESK1 protein protein. 46 1e-04
BC036060-1|AAH36060.2| 400|Homo sapiens mitogen-activated prote... 46 1e-04
BC036013-1|AAH36013.1| 846|Homo sapiens mitogen-activated prote... 46 1e-04
AL591846-12|CAI13544.1| 400|Homo sapiens mitogen-activated prot... 46 1e-04
AL591846-11|CAI13543.1| 370|Homo sapiens mitogen-activated prot... 46 1e-04
AL390029-2|CAI15721.1| 740|Homo sapiens doublecortin and CaM ki... 46 1e-04
AL390029-1|CAI15720.1| 729|Homo sapiens doublecortin and CaM ki... 46 1e-04
AL357874-1|CAI13441.1| 626|Homo sapiens testis-specific kinase ... 46 1e-04
AL160392-2|CAH70261.1| 740|Homo sapiens doublecortin and CaM ki... 46 1e-04
AL160392-1|CAH70262.1| 729|Homo sapiens doublecortin and CaM ki... 46 1e-04
AL157760-4|CAH70170.1| 433|Homo sapiens doublecortin and CaM ki... 46 1e-04
AL157760-2|CAH70167.1| 740|Homo sapiens doublecortin and CaM ki... 46 1e-04
AL157760-1|CAH70168.1| 729|Homo sapiens doublecortin and CaM ki... 46 1e-04
AL157694-2|CAH70656.1| 740|Homo sapiens doublecortin and CaM ki... 46 1e-04
AL157694-1|CAH70657.1| 729|Homo sapiens doublecortin and CaM ki... 46 1e-04
AJ247087-1|CAC42766.1| 795|Homo sapiens myosin light chain kina... 46 1e-04
AF507907-1|AAM50515.1| 244|Homo sapiens testis-specific kinase-... 46 1e-04
AB002367-1|BAA20824.2| 794|Homo sapiens KIAA0369 protein. 46 1e-04
AK096052-1|BAC04688.1| 663|Homo sapiens protein ( Homo sapiens ... 46 2e-04
AJ316534-1|CAC48387.1| 1231|Homo sapiens serine/threonine protei... 46 2e-04
AJ309861-1|CAC32991.1| 212|Homo sapiens putative protein kinase... 46 2e-04
AF390018-1|AAK91995.1| 1243|Homo sapiens putative protein kinase... 46 2e-04
AB209611-1|BAD92848.1| 453|Homo sapiens Mitogen activated prote... 46 2e-04
Z22536-1|CAA80258.1| 505|Homo sapiens ALK-4 protein. 45 2e-04
X90870-1|CAA62378.1| 458|Homo sapiens myosin-light-chain kinase... 45 2e-04
X85545-1|CAA59733.1| 358|Homo sapiens protein kinase protein. 45 2e-04
U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase... 45 2e-04
U14722-1|AAA50246.1| 505|Homo sapiens activin type I receptor p... 45 2e-04
BT007072-1|AAP35735.1| 505|Homo sapiens activin A receptor, typ... 45 2e-04
BC127622-1|AAI27623.1| 596|Homo sapiens myosin light chain kina... 45 2e-04
BC127603-1|AAI27604.1| 829|Homo sapiens kinase suppressor of ra... 45 2e-04
BC107107-1|AAI07108.1| 827|Homo sapiens KSR2 protein protein. 45 2e-04
BC107106-1|AAI07107.1| 827|Homo sapiens KSR2 protein protein. 45 2e-04
BC092413-1|AAH92413.1| 596|Homo sapiens myosin light chain kina... 45 2e-04
BC069627-1|AAH69627.1| 596|Homo sapiens skeletal myosin light c... 45 2e-04
BC041073-1|AAH41073.1| 358|Homo sapiens protein kinase, X-linke... 45 2e-04
BC040531-1|AAH40531.1| 505|Homo sapiens activin A receptor, typ... 45 2e-04
BC009350-1|AAH09350.2| 829|Homo sapiens EIF2AK4 protein protein. 45 2e-04
BC007753-1|AAH07753.1| 242|Homo sapiens Unknown (protein for IM... 45 2e-04
BC000254-1|AAH00254.1| 505|Homo sapiens activin A receptor, typ... 45 2e-04
AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain poly... 45 2e-04
AY424269-1|AAR29061.1| 1845|Homo sapiens myosin light chain poly... 45 2e-04
AY345972-1|AAQ24226.1| 829|Homo sapiens kinase suppressor of Ra... 45 2e-04
AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain... 45 2e-04
AL160175-10|CAC10006.1| 596|Homo sapiens myosin light chain kin... 45 2e-04
AL157497-1|CAB75678.1| 938|Homo sapiens hypothetical protein pr... 45 2e-04
AL035703-1|CAB81612.1| 1005|Homo sapiens EPH receptor A8 protein. 45 2e-04
AJ272502-1|CAC81354.1| 596|Homo sapiens skeletal muscle-specifi... 45 2e-04
AF325549-1|AAK15494.1| 596|Homo sapiens skeletal myosin light c... 45 2e-04
AF069603-1|AAD15923.1| 1793|Homo sapiens myosin light chain kina... 45 2e-04
AF069602-1|AAD15922.1| 1862|Homo sapiens myosin light chain kina... 45 2e-04
AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kina... 45 2e-04
AB040892-1|BAA95983.1| 853|Homo sapiens KIAA1459 protein protein. 45 2e-04
AB037759-1|BAA92576.1| 1495|Homo sapiens KIAA1338 protein protein. 45 2e-04
AB037663-1|BAB21504.1| 992|Homo sapiens myosin light chain kina... 45 2e-04
Z25426-1|CAA80913.1| 113|Homo sapiens protein-serine/threonine ... 45 3e-04
L11695-1|AAA16073.1| 503|Homo sapiens activin receptor-like kin... 45 3e-04
L07868-1|AAB59446.1| 1308|Homo sapiens receptor tyrosine kinase ... 45 3e-04
DQ383424-1|ABD46753.1| 503|Homo sapiens transforming growth fac... 45 3e-04
BC112199-1|AAI12200.1| 1308|Homo sapiens v-erb-a erythroblastic ... 45 3e-04
BC071181-1|AAH71181.1| 426|Homo sapiens TGFBR1 protein protein. 45 3e-04
AY497473-1|AAR32097.1| 503|Homo sapiens transforming growth fac... 45 3e-04
AL162427-1|CAI17140.1| 503|Homo sapiens transforming growth fac... 45 3e-04
AF069604-1|AAD15924.1| 560|Homo sapiens myosin light chain kina... 45 3e-04
AF054598-1|AAC08998.1| 503|Homo sapiens TGF-beta type I recepto... 45 3e-04
AF035670-1|AAD02042.1| 503|Homo sapiens transforming growth fac... 45 3e-04
AC068970-1|AAX88856.1| 136|Homo sapiens unknown protein. 45 3e-04
AB209697-1|BAD92934.1| 892|Homo sapiens v-erb-a erythroblastic ... 45 3e-04
Z48970-1|CAA88834.1| 303|Homo sapiens orf protein. 44 4e-04
X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein. 44 4e-04
X56348-1|CAA39792.1| 435|Homo sapiens urf-ret protein. 44 4e-04
X15786-1|CAA33787.1| 899|Homo sapiens retII protein. 44 4e-04
X12949-1|CAA31408.1| 860|Homo sapiens protein ( Human ret proto... 44 4e-04
U81031-1|AAC39521.2| 303|Homo sapiens CDK4 protein. 44 4e-04
U79269-1|AAB50213.1| 229|Homo sapiens cyclin dependent protein ... 44 4e-04
U37022-1|AAC50506.1| 303|Homo sapiens cyclin-dependent kinase 4... 44 4e-04
S67448-1|AAD13991.1| 89|Homo sapiens CDK4 protein. 44 4e-04
M83941-1|AAA58633.1| 983|Homo sapiens receptor protein kinase p... 44 4e-04
M31213-1|AAA36524.1| 503|Homo sapiens protein ( Human papillary... 44 4e-04
M14505-1|AAA35673.1| 303|Homo sapiens cyclin-dependent protein ... 44 4e-04
J00119-1|AAA52029.1| 346|Homo sapiens MOS protein. 44 4e-04
DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protei... 44 4e-04
DQ316259-1|ABC40748.1| 516|Homo sapiens nemo like kinase protein. 44 4e-04
DQ104207-1|AAZ57203.1| 776|Homo sapiens HOOK3-RET fusion protei... 44 4e-04
CR542247-1|CAG47043.1| 303|Homo sapiens CDK4 protein. 44 4e-04
CR407668-1|CAG28596.1| 303|Homo sapiens CDK4 protein. 44 4e-04
BT006935-1|AAP35581.1| 367|Homo sapiens death-associated protei... 44 4e-04
BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protei... 44 4e-04
BC106737-1|AAI06738.1| 346|Homo sapiens v-mos Moloney murine sa... 44 4e-04
BC069590-1|AAH69590.1| 346|Homo sapiens MOS protein protein. 44 4e-04
BC069569-1|AAH69569.1| 346|Homo sapiens v-mos Moloney murine sa... 44 4e-04
BC064663-1|AAH64663.1| 515|Homo sapiens nemo-like kinase protein. 44 4e-04
BC063282-1|AAH63282.1| 983|Homo sapiens EPH receptor A3 protein. 44 4e-04
BC015191-1|AAH15191.1| 322|Homo sapiens PDZ binding kinase prot... 44 4e-04
BC010153-1|AAH10153.1| 303|Homo sapiens cyclin-dependent kinase... 44 4e-04
BC005864-1|AAH05864.1| 303|Homo sapiens cyclin-dependent kinase... 44 4e-04
BC004257-1|AAH04257.1| 1072|Homo sapiens ret proto-oncogene prot... 44 4e-04
BC003644-1|AAH03644.1| 303|Homo sapiens cyclin-dependent kinase... 44 4e-04
AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protei... 44 4e-04
AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protei... 44 4e-04
AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protei... 44 4e-04
AF507942-1|AAM23014.1| 303|Homo sapiens cyclin-dependent kinase... 44 4e-04
AF237709-1|AAF71521.1| 322|Homo sapiens spermatogenesis-related... 44 4e-04
AF213459-1|AAG43576.1| 983|Homo sapiens ephrin receptor EPHA3 c... 44 4e-04
AF197898-1|AAF04857.1| 515|Homo sapiens nemo-like kinase protein. 44 4e-04
AF189722-1|AAF69107.1| 322|Homo sapiens PDZ-binding kinase prot... 44 4e-04
AF180819-1|AAD56013.1| 515|Homo sapiens LAK1 protein protein. 44 4e-04
AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein DK... 44 4e-04
AB027250-1|BAA99577.1| 322|Homo sapiens MPAKK-like protein kina... 44 4e-04
AB027249-1|BAA99576.1| 322|Homo sapiens MAPKK like protein kina... 44 4e-04
Y15801-1|CAA75792.1| 277|Homo sapiens protein kinase protein. 44 5e-04
Y13927-1|CAA74244.1| 277|Homo sapiens protein kinase protein. 44 5e-04
U29727-1|AAA82933.1| 816|Homo sapiens BMK1 gamma kinase protein. 44 5e-04
U29726-1|AAA82932.1| 816|Homo sapiens BMK1 beta kinase protein. 44 5e-04
U29725-1|AAA82931.1| 816|Homo sapiens BMK1 alpha kinase protein. 44 5e-04
U25278-1|AAA81381.1| 815|Homo sapiens ERK5 protein. 44 5e-04
M16029-1|AAA36786.1| 805|Homo sapiens protein ( Human ret mRNA ... 44 5e-04
L03357-1|AAA60266.1| 593|Homo sapiens RET tyrosine kinase/cAMP ... 44 5e-04
BC126432-1|AAI26433.1| 454|Homo sapiens death-associated protei... 44 5e-04
BC126430-1|AAI26431.1| 454|Homo sapiens death-associated protei... 44 5e-04
BC110618-1|AAI10619.1| 784|Homo sapiens receptor-interacting se... 44 5e-04
BC110617-1|AAI10618.1| 784|Homo sapiens receptor-interacting se... 44 5e-04
BC106738-1|AAI06739.1| 346|Homo sapiens v-mos Moloney murine sa... 44 5e-04
BC074852-1|AAH74852.1| 277|Homo sapiens protein kinase, Y-linke... 44 5e-04
BC074851-1|AAH74851.1| 277|Homo sapiens protein kinase, Y-linke... 44 5e-04
BC071579-1|AAH71579.1| 873|Homo sapiens MAP4K3 protein protein. 44 5e-04
BC030134-1|AAH30134.1| 816|Homo sapiens mitogen-activated prote... 44 5e-04
BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein. 44 5e-04
BC009963-1|AAH09963.1| 816|Homo sapiens mitogen-activated prote... 44 5e-04
BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein. 44 5e-04
BC004553-1|AAH04553.1| 540|Homo sapiens receptor-interacting se... 44 5e-04
BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein. 44 5e-04
BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein. 44 5e-04
AY534741-1|AAS38577.1| 533|Homo sapiens mitogen activated prote... 44 5e-04
AY524045-1|AAS94254.1| 540|Homo sapiens GIG30 protein. 44 5e-04
AY358814-1|AAQ89173.1| 540|Homo sapiens RIPK2 protein. 44 5e-04
AP001743-1|BAA95526.1| 832|Homo sapiens ANKRD3 protein. 44 5e-04
AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein. 44 5e-04
AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein. 44 5e-04
AK098831-1|BAC05426.1| 439|Homo sapiens protein ( Homo sapiens ... 44 5e-04
AK027424-1|BAB55102.1| 784|Homo sapiens protein ( Homo sapiens ... 44 5e-04
AJ278016-1|CAC04247.1| 784|Homo sapiens protein kinase protein. 44 5e-04
AJ243297-1|CAB46483.1| 1091|Homo sapiens RET tyrosine kinase rec... 44 5e-04
AF445413-2|AAN75850.1| 873|Homo sapiens MAP4K3 protein. 44 5e-04
AF445413-1|AAN75849.1| 894|Homo sapiens MAP4K3 protein. 44 5e-04
AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine ... 44 5e-04
AF078530-1|AAC27722.1| 540|Homo sapiens receptor interacting pr... 44 5e-04
AF064824-1|AAC25668.1| 540|Homo sapiens CARD-containing ICE ass... 44 5e-04
AF027706-1|AAC34970.1| 540|Homo sapiens serine/threonine kinase... 44 5e-04
AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase... 44 5e-04
AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1... 44 5e-04
AF000145-1|AAC15472.1| 884|Homo sapiens germinal center kinase ... 44 5e-04
AC007684-1|AAF19240.1| 712|Homo sapiens unknown protein. 44 5e-04
AC004003-1|AAC24561.1| 540|Homo sapiens WUGSC:H_RG437L15.1 prot... 44 5e-04
AB047783-1|BAB56136.1| 784|Homo sapiens probable dual-specifici... 44 5e-04
AB022341-1|BAA81746.1| 454|Homo sapiens ZIP kinase protein. 44 5e-04
AB007144-1|BAA24955.1| 454|Homo sapiens ZIP-kinase protein. 44 5e-04
U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-co... 44 7e-04
L33801-1|AAA66475.1| 420|Homo sapiens protein kinase protein. 44 7e-04
CR536510-1|CAG38748.1| 420|Homo sapiens GSK3B protein. 44 7e-04
BC012760-1|AAH12760.1| 420|Homo sapiens GSK3B protein protein. 44 7e-04
BC007992-1|AAH07992.1| 677|Homo sapiens mitogen-activated prote... 44 7e-04
BC007404-1|AAH07404.1| 677|Homo sapiens mitogen-activated prote... 44 7e-04
BC000251-1|AAH00251.1| 433|Homo sapiens glycogen synthase kinas... 44 7e-04
AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal ... 44 7e-04
AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal ... 44 7e-04
AK131512-1|BAD18656.1| 345|Homo sapiens protein ( Homo sapiens ... 44 7e-04
AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein. 44 7e-04
Z25421-1|CAA80908.1| 127|Homo sapiens protein-serine/threonine ... 43 9e-04
Y10256-1|CAA71306.1| 947|Homo sapiens NIK, serine/threonine pro... 43 9e-04
X85337-1|CAA59685.1| 991|Homo sapiens myosin light chain kinase... 43 9e-04
X66365-1|CAA47008.1| 326|Homo sapiens serine/threonine protein ... 43 9e-04
X66362-1|CAA47005.1| 380|Homo sapiens serine/threonine protein ... 43 9e-04
D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein. 43 9e-04
D50927-1|BAA09486.2| 801|Homo sapiens KIAA0137 protein protein. 43 9e-04
DQ314874-1|ABC40733.1| 947|Homo sapiens mitogen-activated prote... 43 9e-04
BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein. 43 9e-04
BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein. 43 9e-04
BC111088-1|AAI11089.1| 252|Homo sapiens TSSK4 protein protein. 43 9e-04
BC052264-1|AAH52264.1| 326|Homo sapiens cyclin-dependent kinase... 43 9e-04
BC044925-1|AAH44925.2| 830|Homo sapiens TLK2 protein protein. 43 9e-04
BC035576-1|AAH35576.1| 947|Homo sapiens mitogen-activated prote... 43 9e-04
BC032657-1|AAH32657.1| 766|Homo sapiens tousled-like kinase 1 p... 43 9e-04
AY461663-1|AAS17971.1| 328|Homo sapiens testis-specific serine ... 43 9e-04
AY128534-1|AAM76970.1| 326|Homo sapiens cyclin-dependent kinase... 43 9e-04
AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule affinit... 43 9e-04
AK027493-1|BAB55152.1| 638|Homo sapiens protein ( Homo sapiens ... 43 9e-04
AJ844634-1|CAH59749.2| 84|Homo sapiens serine/threonine kinase... 43 9e-04
AJ541797-1|CAD62569.2| 765|Homo sapiens ankyrin repeat and kina... 43 9e-04
AJ277481-1|CAB94832.1| 452|Homo sapiens integrin-linked kinase-... 43 9e-04
AF525298-1|AAM91924.1| 765|Homo sapiens X-kinase protein. 43 9e-04
AF487542-1|AAQ09005.1| 765|Homo sapiens protein kinase PKK2 pro... 43 9e-04
AF246219-1|AAF71263.1| 549|Homo sapiens SNARE protein kinase SN... 43 9e-04
AF162667-1|AAF03095.1| 749|Homo sapiens tousled-like kinase 2 p... 43 9e-04
AF162666-1|AAF03094.1| 718|Homo sapiens tousled-like kinase 1 p... 43 9e-04
>DQ314875-1|ABC40734.1| 606|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 606
Score = 156 bits (379), Expect = 6e-38
Identities = 81/143 (56%), Positives = 94/143 (65%), Gaps = 3/143 (2%)
Frame = +2
Query: 257 AEGGSLYNVLHN-RPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVG 433
AEGGSLYNVLH P P YTAAHAMSW QC++GVAYLHSM+PK LIHRDLKPPNLLLV
Sbjct: 107 AEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVA 166
Query: 434 GGQRLKICDFGTAADKATYMTNNKGVLLGWLLR--YLKDRHTQKNVMCSHXXXXXXXXXX 607
GG LKICDFGTA D T+MTNNKG W+ + +++K + S
Sbjct: 167 GGTVLKICDFGTACDIQTHMTNNKG-SAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITR 225
Query: 608 XXNHFEEGGSAYRIMWAVHTRSK 676
E GG A+RIMWAVH ++
Sbjct: 226 RKPFDEIGGPAFRIMWAVHNGTR 248
Score = 102 bits (245), Expect = 1e-21
Identities = 50/79 (63%), Positives = 60/79 (75%)
Frame = +3
Query: 18 EEIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEKREFAIEVRQLSRVCHPN 197
EEIDY EI+ VVG+GAFGVV K WR + VA+K I SE+E++ F +E+RQLSRV HPN
Sbjct: 29 EEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPN 88
Query: 198 IVRLYGACTRGAHVCLVME 254
IV+LYGAC VCLVME
Sbjct: 89 IVKLYGACLN--PVCLVME 105
>BT019654-1|AAV38460.1| 579|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 579
Score = 156 bits (379), Expect = 6e-38
Identities = 81/143 (56%), Positives = 94/143 (65%), Gaps = 3/143 (2%)
Frame = +2
Query: 257 AEGGSLYNVLHN-RPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVG 433
AEGGSLYNVLH P P YTAAHAMSW QC++GVAYLHSM+PK LIHRDLKPPNLLLV
Sbjct: 107 AEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVA 166
Query: 434 GGQRLKICDFGTAADKATYMTNNKGVLLGWLLR--YLKDRHTQKNVMCSHXXXXXXXXXX 607
GG LKICDFGTA D T+MTNNKG W+ + +++K + S
Sbjct: 167 GGTVLKICDFGTACDIQTHMTNNKG-SAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITR 225
Query: 608 XXNHFEEGGSAYRIMWAVHTRSK 676
E GG A+RIMWAVH ++
Sbjct: 226 RKPFDEIGGPAFRIMWAVHNGTR 248
Score = 102 bits (245), Expect = 1e-21
Identities = 50/79 (63%), Positives = 60/79 (75%)
Frame = +3
Query: 18 EEIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEKREFAIEVRQLSRVCHPN 197
EEIDY EI+ VVG+GAFGVV K WR + VA+K I SE+E++ F +E+RQLSRV HPN
Sbjct: 29 EEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPN 88
Query: 198 IVRLYGACTRGAHVCLVME 254
IV+LYGAC VCLVME
Sbjct: 89 IVKLYGACLN--PVCLVME 105
>BC017715-1|AAH17715.1| 579|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 579
Score = 156 bits (379), Expect = 6e-38
Identities = 81/143 (56%), Positives = 94/143 (65%), Gaps = 3/143 (2%)
Frame = +2
Query: 257 AEGGSLYNVLHN-RPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVG 433
AEGGSLYNVLH P P YTAAHAMSW QC++GVAYLHSM+PK LIHRDLKPPNLLLV
Sbjct: 107 AEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVA 166
Query: 434 GGQRLKICDFGTAADKATYMTNNKGVLLGWLLR--YLKDRHTQKNVMCSHXXXXXXXXXX 607
GG LKICDFGTA D T+MTNNKG W+ + +++K + S
Sbjct: 167 GGTVLKICDFGTACDIQTHMTNNKG-SAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITR 225
Query: 608 XXNHFEEGGSAYRIMWAVHTRSK 676
E GG A+RIMWAVH ++
Sbjct: 226 RKPFDEIGGPAFRIMWAVHNGTR 248
Score = 102 bits (245), Expect = 1e-21
Identities = 50/79 (63%), Positives = 60/79 (75%)
Frame = +3
Query: 18 EEIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEKREFAIEVRQLSRVCHPN 197
EEIDY EI+ VVG+GAFGVV K WR + VA+K I SE+E++ F +E+RQLSRV HPN
Sbjct: 29 EEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPN 88
Query: 198 IVRLYGACTRGAHVCLVME 254
IV+LYGAC VCLVME
Sbjct: 89 IVKLYGACLN--PVCLVME 105
>AL121964-4|CAI19611.1| 579|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 579
Score = 156 bits (379), Expect = 6e-38
Identities = 81/143 (56%), Positives = 94/143 (65%), Gaps = 3/143 (2%)
Frame = +2
Query: 257 AEGGSLYNVLHN-RPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVG 433
AEGGSLYNVLH P P YTAAHAMSW QC++GVAYLHSM+PK LIHRDLKPPNLLLV
Sbjct: 107 AEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVA 166
Query: 434 GGQRLKICDFGTAADKATYMTNNKGVLLGWLLR--YLKDRHTQKNVMCSHXXXXXXXXXX 607
GG LKICDFGTA D T+MTNNKG W+ + +++K + S
Sbjct: 167 GGTVLKICDFGTACDIQTHMTNNKG-SAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITR 225
Query: 608 XXNHFEEGGSAYRIMWAVHTRSK 676
E GG A+RIMWAVH ++
Sbjct: 226 RKPFDEIGGPAFRIMWAVHNGTR 248
Score = 102 bits (245), Expect = 1e-21
Identities = 50/79 (63%), Positives = 60/79 (75%)
Frame = +3
Query: 18 EEIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEKREFAIEVRQLSRVCHPN 197
EEIDY EI+ VVG+GAFGVV K WR + VA+K I SE+E++ F +E+RQLSRV HPN
Sbjct: 29 EEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPN 88
Query: 198 IVRLYGACTRGAHVCLVME 254
IV+LYGAC VCLVME
Sbjct: 89 IVKLYGACLN--PVCLVME 105
>AL121964-3|CAI19612.1| 606|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 606
Score = 156 bits (379), Expect = 6e-38
Identities = 81/143 (56%), Positives = 94/143 (65%), Gaps = 3/143 (2%)
Frame = +2
Query: 257 AEGGSLYNVLHN-RPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVG 433
AEGGSLYNVLH P P YTAAHAMSW QC++GVAYLHSM+PK LIHRDLKPPNLLLV
Sbjct: 107 AEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVA 166
Query: 434 GGQRLKICDFGTAADKATYMTNNKGVLLGWLLR--YLKDRHTQKNVMCSHXXXXXXXXXX 607
GG LKICDFGTA D T+MTNNKG W+ + +++K + S
Sbjct: 167 GGTVLKICDFGTACDIQTHMTNNKG-SAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITR 225
Query: 608 XXNHFEEGGSAYRIMWAVHTRSK 676
E GG A+RIMWAVH ++
Sbjct: 226 RKPFDEIGGPAFRIMWAVHNGTR 248
Score = 102 bits (245), Expect = 1e-21
Identities = 50/79 (63%), Positives = 60/79 (75%)
Frame = +3
Query: 18 EEIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEKREFAIEVRQLSRVCHPN 197
EEIDY EI+ VVG+GAFGVV K WR + VA+K I SE+E++ F +E+RQLSRV HPN
Sbjct: 29 EEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPN 88
Query: 198 IVRLYGACTRGAHVCLVME 254
IV+LYGAC VCLVME
Sbjct: 89 IVKLYGACLN--PVCLVME 105
>AL121964-2|CAI19609.1| 491|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 491
Score = 156 bits (379), Expect = 6e-38
Identities = 81/143 (56%), Positives = 94/143 (65%), Gaps = 3/143 (2%)
Frame = +2
Query: 257 AEGGSLYNVLHN-RPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVG 433
AEGGSLYNVLH P P YTAAHAMSW QC++GVAYLHSM+PK LIHRDLKPPNLLLV
Sbjct: 107 AEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVA 166
Query: 434 GGQRLKICDFGTAADKATYMTNNKGVLLGWLLR--YLKDRHTQKNVMCSHXXXXXXXXXX 607
GG LKICDFGTA D T+MTNNKG W+ + +++K + S
Sbjct: 167 GGTVLKICDFGTACDIQTHMTNNKG-SAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITR 225
Query: 608 XXNHFEEGGSAYRIMWAVHTRSK 676
E GG A+RIMWAVH ++
Sbjct: 226 RKPFDEIGGPAFRIMWAVHNGTR 248
Score = 102 bits (245), Expect = 1e-21
Identities = 50/79 (63%), Positives = 60/79 (75%)
Frame = +3
Query: 18 EEIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEKREFAIEVRQLSRVCHPN 197
EEIDY EI+ VVG+GAFGVV K WR + VA+K I SE+E++ F +E+RQLSRV HPN
Sbjct: 29 EEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPN 88
Query: 198 IVRLYGACTRGAHVCLVME 254
IV+LYGAC VCLVME
Sbjct: 89 IVKLYGACLN--PVCLVME 105
>AL121964-1|CAI19610.1| 518|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 518
Score = 156 bits (379), Expect = 6e-38
Identities = 81/143 (56%), Positives = 94/143 (65%), Gaps = 3/143 (2%)
Frame = +2
Query: 257 AEGGSLYNVLHN-RPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVG 433
AEGGSLYNVLH P P YTAAHAMSW QC++GVAYLHSM+PK LIHRDLKPPNLLLV
Sbjct: 107 AEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVA 166
Query: 434 GGQRLKICDFGTAADKATYMTNNKGVLLGWLLR--YLKDRHTQKNVMCSHXXXXXXXXXX 607
GG LKICDFGTA D T+MTNNKG W+ + +++K + S
Sbjct: 167 GGTVLKICDFGTACDIQTHMTNNKG-SAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITR 225
Query: 608 XXNHFEEGGSAYRIMWAVHTRSK 676
E GG A+RIMWAVH ++
Sbjct: 226 RKPFDEIGGPAFRIMWAVHNGTR 248
Score = 102 bits (245), Expect = 1e-21
Identities = 50/79 (63%), Positives = 60/79 (75%)
Frame = +3
Query: 18 EEIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEKREFAIEVRQLSRVCHPN 197
EEIDY EI+ VVG+GAFGVV K WR + VA+K I SE+E++ F +E+RQLSRV HPN
Sbjct: 29 EEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPN 88
Query: 198 IVRLYGACTRGAHVCLVME 254
IV+LYGAC VCLVME
Sbjct: 89 IVKLYGACLN--PVCLVME 105
>AL121837-4|CAI23533.1| 579|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 579
Score = 156 bits (379), Expect = 6e-38
Identities = 81/143 (56%), Positives = 94/143 (65%), Gaps = 3/143 (2%)
Frame = +2
Query: 257 AEGGSLYNVLHN-RPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVG 433
AEGGSLYNVLH P P YTAAHAMSW QC++GVAYLHSM+PK LIHRDLKPPNLLLV
Sbjct: 107 AEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVA 166
Query: 434 GGQRLKICDFGTAADKATYMTNNKGVLLGWLLR--YLKDRHTQKNVMCSHXXXXXXXXXX 607
GG LKICDFGTA D T+MTNNKG W+ + +++K + S
Sbjct: 167 GGTVLKICDFGTACDIQTHMTNNKG-SAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITR 225
Query: 608 XXNHFEEGGSAYRIMWAVHTRSK 676
E GG A+RIMWAVH ++
Sbjct: 226 RKPFDEIGGPAFRIMWAVHNGTR 248
Score = 102 bits (245), Expect = 1e-21
Identities = 50/79 (63%), Positives = 60/79 (75%)
Frame = +3
Query: 18 EEIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEKREFAIEVRQLSRVCHPN 197
EEIDY EI+ VVG+GAFGVV K WR + VA+K I SE+E++ F +E+RQLSRV HPN
Sbjct: 29 EEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPN 88
Query: 198 IVRLYGACTRGAHVCLVME 254
IV+LYGAC VCLVME
Sbjct: 89 IVKLYGACLN--PVCLVME 105
>AL121837-3|CAI23532.1| 606|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 606
Score = 156 bits (379), Expect = 6e-38
Identities = 81/143 (56%), Positives = 94/143 (65%), Gaps = 3/143 (2%)
Frame = +2
Query: 257 AEGGSLYNVLHN-RPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVG 433
AEGGSLYNVLH P P YTAAHAMSW QC++GVAYLHSM+PK LIHRDLKPPNLLLV
Sbjct: 107 AEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVA 166
Query: 434 GGQRLKICDFGTAADKATYMTNNKGVLLGWLLR--YLKDRHTQKNVMCSHXXXXXXXXXX 607
GG LKICDFGTA D T+MTNNKG W+ + +++K + S
Sbjct: 167 GGTVLKICDFGTACDIQTHMTNNKG-SAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITR 225
Query: 608 XXNHFEEGGSAYRIMWAVHTRSK 676
E GG A+RIMWAVH ++
Sbjct: 226 RKPFDEIGGPAFRIMWAVHNGTR 248
Score = 102 bits (245), Expect = 1e-21
Identities = 50/79 (63%), Positives = 60/79 (75%)
Frame = +3
Query: 18 EEIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEKREFAIEVRQLSRVCHPN 197
EEIDY EI+ VVG+GAFGVV K WR + VA+K I SE+E++ F +E+RQLSRV HPN
Sbjct: 29 EEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPN 88
Query: 198 IVRLYGACTRGAHVCLVME 254
IV+LYGAC VCLVME
Sbjct: 89 IVKLYGACLN--PVCLVME 105
>AL121837-2|CAI23531.1| 491|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 491
Score = 156 bits (379), Expect = 6e-38
Identities = 81/143 (56%), Positives = 94/143 (65%), Gaps = 3/143 (2%)
Frame = +2
Query: 257 AEGGSLYNVLHN-RPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVG 433
AEGGSLYNVLH P P YTAAHAMSW QC++GVAYLHSM+PK LIHRDLKPPNLLLV
Sbjct: 107 AEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVA 166
Query: 434 GGQRLKICDFGTAADKATYMTNNKGVLLGWLLR--YLKDRHTQKNVMCSHXXXXXXXXXX 607
GG LKICDFGTA D T+MTNNKG W+ + +++K + S
Sbjct: 167 GGTVLKICDFGTACDIQTHMTNNKG-SAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITR 225
Query: 608 XXNHFEEGGSAYRIMWAVHTRSK 676
E GG A+RIMWAVH ++
Sbjct: 226 RKPFDEIGGPAFRIMWAVHNGTR 248
Score = 102 bits (245), Expect = 1e-21
Identities = 50/79 (63%), Positives = 60/79 (75%)
Frame = +3
Query: 18 EEIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEKREFAIEVRQLSRVCHPN 197
EEIDY EI+ VVG+GAFGVV K WR + VA+K I SE+E++ F +E+RQLSRV HPN
Sbjct: 29 EEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPN 88
Query: 198 IVRLYGACTRGAHVCLVME 254
IV+LYGAC VCLVME
Sbjct: 89 IVKLYGACLN--PVCLVME 105
>AL121837-1|CAI23530.1| 518|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 518
Score = 156 bits (379), Expect = 6e-38
Identities = 81/143 (56%), Positives = 94/143 (65%), Gaps = 3/143 (2%)
Frame = +2
Query: 257 AEGGSLYNVLHN-RPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVG 433
AEGGSLYNVLH P P YTAAHAMSW QC++GVAYLHSM+PK LIHRDLKPPNLLLV
Sbjct: 107 AEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVA 166
Query: 434 GGQRLKICDFGTAADKATYMTNNKGVLLGWLLR--YLKDRHTQKNVMCSHXXXXXXXXXX 607
GG LKICDFGTA D T+MTNNKG W+ + +++K + S
Sbjct: 167 GGTVLKICDFGTACDIQTHMTNNKG-SAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITR 225
Query: 608 XXNHFEEGGSAYRIMWAVHTRSK 676
E GG A+RIMWAVH ++
Sbjct: 226 RKPFDEIGGPAFRIMWAVHNGTR 248
Score = 102 bits (245), Expect = 1e-21
Identities = 50/79 (63%), Positives = 60/79 (75%)
Frame = +3
Query: 18 EEIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEKREFAIEVRQLSRVCHPN 197
EEIDY EI+ VVG+GAFGVV K WR + VA+K I SE+E++ F +E+RQLSRV HPN
Sbjct: 29 EEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPN 88
Query: 198 IVRLYGACTRGAHVCLVME 254
IV+LYGAC VCLVME
Sbjct: 89 IVKLYGACLN--PVCLVME 105
>AF218074-1|AAF27652.1| 491|Homo sapiens TGF beta-activated kinase
splice variant d protein.
Length = 491
Score = 156 bits (379), Expect = 6e-38
Identities = 81/143 (56%), Positives = 94/143 (65%), Gaps = 3/143 (2%)
Frame = +2
Query: 257 AEGGSLYNVLHN-RPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVG 433
AEGGSLYNVLH P P YTAAHAMSW QC++GVAYLHSM+PK LIHRDLKPPNLLLV
Sbjct: 107 AEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVA 166
Query: 434 GGQRLKICDFGTAADKATYMTNNKGVLLGWLLR--YLKDRHTQKNVMCSHXXXXXXXXXX 607
GG LKICDFGTA D T+MTNNKG W+ + +++K + S
Sbjct: 167 GGTVLKICDFGTACDIQTHMTNNKG-SAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITR 225
Query: 608 XXNHFEEGGSAYRIMWAVHTRSK 676
E GG A+RIMWAVH ++
Sbjct: 226 RKPFDEIGGPAFRIMWAVHNGTR 248
Score = 102 bits (245), Expect = 1e-21
Identities = 50/79 (63%), Positives = 60/79 (75%)
Frame = +3
Query: 18 EEIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEKREFAIEVRQLSRVCHPN 197
EEIDY EI+ VVG+GAFGVV K WR + VA+K I SE+E++ F +E+RQLSRV HPN
Sbjct: 29 EEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPN 88
Query: 198 IVRLYGACTRGAHVCLVME 254
IV+LYGAC VCLVME
Sbjct: 89 IVKLYGACLN--PVCLVME 105
>AB009358-1|BAA25027.2| 518|Homo sapiens TGF-beta activated kinase
1c protein.
Length = 518
Score = 156 bits (379), Expect = 6e-38
Identities = 81/143 (56%), Positives = 94/143 (65%), Gaps = 3/143 (2%)
Frame = +2
Query: 257 AEGGSLYNVLHN-RPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVG 433
AEGGSLYNVLH P P YTAAHAMSW QC++GVAYLHSM+PK LIHRDLKPPNLLLV
Sbjct: 107 AEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVA 166
Query: 434 GGQRLKICDFGTAADKATYMTNNKGVLLGWLLR--YLKDRHTQKNVMCSHXXXXXXXXXX 607
GG LKICDFGTA D T+MTNNKG W+ + +++K + S
Sbjct: 167 GGTVLKICDFGTACDIQTHMTNNKG-SAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITR 225
Query: 608 XXNHFEEGGSAYRIMWAVHTRSK 676
E GG A+RIMWAVH ++
Sbjct: 226 RKPFDEIGGPAFRIMWAVHNGTR 248
Score = 102 bits (245), Expect = 1e-21
Identities = 50/79 (63%), Positives = 60/79 (75%)
Frame = +3
Query: 18 EEIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEKREFAIEVRQLSRVCHPN 197
EEIDY EI+ VVG+GAFGVV K WR + VA+K I SE+E++ F +E+RQLSRV HPN
Sbjct: 29 EEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPN 88
Query: 198 IVRLYGACTRGAHVCLVME 254
IV+LYGAC VCLVME
Sbjct: 89 IVKLYGACLN--PVCLVME 105
>AB009357-1|BAA25026.1| 606|Homo sapiens TGF-beta activated kinase
1b protein.
Length = 606
Score = 156 bits (379), Expect = 6e-38
Identities = 81/143 (56%), Positives = 94/143 (65%), Gaps = 3/143 (2%)
Frame = +2
Query: 257 AEGGSLYNVLHN-RPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVG 433
AEGGSLYNVLH P P YTAAHAMSW QC++GVAYLHSM+PK LIHRDLKPPNLLLV
Sbjct: 107 AEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVA 166
Query: 434 GGQRLKICDFGTAADKATYMTNNKGVLLGWLLR--YLKDRHTQKNVMCSHXXXXXXXXXX 607
GG LKICDFGTA D T+MTNNKG W+ + +++K + S
Sbjct: 167 GGTVLKICDFGTACDIQTHMTNNKG-SAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITR 225
Query: 608 XXNHFEEGGSAYRIMWAVHTRSK 676
E GG A+RIMWAVH ++
Sbjct: 226 RKPFDEIGGPAFRIMWAVHNGTR 248
Score = 102 bits (245), Expect = 1e-21
Identities = 50/79 (63%), Positives = 60/79 (75%)
Frame = +3
Query: 18 EEIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEKREFAIEVRQLSRVCHPN 197
EEIDY EI+ VVG+GAFGVV K WR + VA+K I SE+E++ F +E+RQLSRV HPN
Sbjct: 29 EEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPN 88
Query: 198 IVRLYGACTRGAHVCLVME 254
IV+LYGAC VCLVME
Sbjct: 89 IVKLYGACLN--PVCLVME 105
>AB009356-1|BAA25025.1| 579|Homo sapiens TGF-beta activated kinase
1a protein.
Length = 579
Score = 156 bits (379), Expect = 6e-38
Identities = 81/143 (56%), Positives = 94/143 (65%), Gaps = 3/143 (2%)
Frame = +2
Query: 257 AEGGSLYNVLHN-RPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVG 433
AEGGSLYNVLH P P YTAAHAMSW QC++GVAYLHSM+PK LIHRDLKPPNLLLV
Sbjct: 107 AEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVA 166
Query: 434 GGQRLKICDFGTAADKATYMTNNKGVLLGWLLR--YLKDRHTQKNVMCSHXXXXXXXXXX 607
GG LKICDFGTA D T+MTNNKG W+ + +++K + S
Sbjct: 167 GGTVLKICDFGTACDIQTHMTNNKG-SAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITR 225
Query: 608 XXNHFEEGGSAYRIMWAVHTRSK 676
E GG A+RIMWAVH ++
Sbjct: 226 RKPFDEIGGPAFRIMWAVHNGTR 248
Score = 102 bits (245), Expect = 1e-21
Identities = 50/79 (63%), Positives = 60/79 (75%)
Frame = +3
Query: 18 EEIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEKREFAIEVRQLSRVCHPN 197
EEIDY EI+ VVG+GAFGVV K WR + VA+K I SE+E++ F +E+RQLSRV HPN
Sbjct: 29 EEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPN 88
Query: 198 IVRLYGACTRGAHVCLVME 254
IV+LYGAC VCLVME
Sbjct: 89 IVKLYGACLN--PVCLVME 105
>BT019655-1|AAV38461.1| 606|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 606
Score = 156 bits (378), Expect = 8e-38
Identities = 81/143 (56%), Positives = 93/143 (65%), Gaps = 3/143 (2%)
Frame = +2
Query: 257 AEGGSLYNVLHN-RPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVG 433
AEGGSLYNVLH P P YTAAHAMSW QC++GVAYLHSM+PK LIHRDLKPPNLLLV
Sbjct: 107 AEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVA 166
Query: 434 GGQRLKICDFGTAADKATYMTNNKGVLLGWLLR--YLKDRHTQKNVMCSHXXXXXXXXXX 607
GG LKICDFGTA D T+MTNNKG W+ + + +K + S
Sbjct: 167 GGTVLKICDFGTACDIQTHMTNNKG-SAAWMAPEVFEGSNYNEKCDVFSWGIILWEVITR 225
Query: 608 XXNHFEEGGSAYRIMWAVHTRSK 676
E GG A+RIMWAVH ++
Sbjct: 226 RKPFDEIGGPAFRIMWAVHNGTR 248
Score = 102 bits (245), Expect = 1e-21
Identities = 50/79 (63%), Positives = 60/79 (75%)
Frame = +3
Query: 18 EEIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEKREFAIEVRQLSRVCHPN 197
EEIDY EI+ VVG+GAFGVV K WR + VA+K I SE+E++ F +E+RQLSRV HPN
Sbjct: 29 EEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPN 88
Query: 198 IVRLYGACTRGAHVCLVME 254
IV+LYGAC VCLVME
Sbjct: 89 IVKLYGACLN--PVCLVME 105
>Z48615-1|CAA88531.1| 953|Homo sapiens serine/threonine kinase with
SH3 domain, leucine zipper domain and proline rich
protein.
Length = 953
Score = 64.9 bits (151), Expect = 2e-10
Identities = 33/85 (38%), Positives = 46/85 (54%), Gaps = 6/85 (7%)
Frame = +3
Query: 18 EEIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEK------REFAIEVRQLS 179
+EI + E+Q ++G G FG V++ +WR VAVK + EK + E R
Sbjct: 91 QEIPFHELQLEEIIGVGGFGKVYRALWRGEEVAVKAARLDPEKDPAVTAEQVCQEARLFG 150
Query: 180 RVCHPNIVRLYGACTRGAHVCLVME 254
+ HPNI+ L GAC H+CLVME
Sbjct: 151 ALQHPNIIALRGACLNPPHLCLVME 175
Score = 54.8 bits (126), Expect = 3e-07
Identities = 36/89 (40%), Positives = 49/89 (55%), Gaps = 9/89 (10%)
Frame = +2
Query: 257 AEGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGG 436
A GG+L VL R P + ++WA Q A G+ YLH+ P P+IHRDLK N+L++
Sbjct: 177 ARGGALSRVLAGRRVPPHVL---VNWAVQVARGMNYLHNDAPVPIIHRDLKSINILILEA 233
Query: 437 GQR-------LKICDFGTAAD--KATYMT 496
+ LKI DFG A + K T M+
Sbjct: 234 IENHNLADTVLKITDFGLAREWHKTTKMS 262
Score = 45.2 bits (102), Expect = 2e-04
Identities = 17/36 (47%), Positives = 27/36 (75%)
Frame = +1
Query: 514 AWMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRKPF 621
AWMAPEV S +++ DV+S+G++LWE+L+ P+
Sbjct: 268 AWMAPEVIRLSLFSKSSDVWSFGVLLWELLTGEVPY 303
>X90846-1|CAA62351.1| 954|Homo sapiens mixed lineage kinase 2
protein.
Length = 954
Score = 64.9 bits (151), Expect = 2e-10
Identities = 33/85 (38%), Positives = 46/85 (54%), Gaps = 6/85 (7%)
Frame = +3
Query: 18 EEIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEK------REFAIEVRQLS 179
+EI + E+Q ++G G FG V++ +WR VAVK + EK + E R
Sbjct: 91 QEIPFHELQLEEIIGVGGFGKVYRALWRGEEVAVKAARLDPEKDPAVTAEQVCQEARLFG 150
Query: 180 RVCHPNIVRLYGACTRGAHVCLVME 254
+ HPNI+ L GAC H+CLVME
Sbjct: 151 ALQHPNIIALRGACLNPPHLCLVME 175
Score = 54.8 bits (126), Expect = 3e-07
Identities = 36/89 (40%), Positives = 49/89 (55%), Gaps = 9/89 (10%)
Frame = +2
Query: 257 AEGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGG 436
A GG+L VL R P + ++WA Q A G+ YLH+ P P+IHRDLK N+L++
Sbjct: 177 ARGGALSRVLAGRRVPPHVL---VNWAVQVARGMNYLHNDAPVPIIHRDLKSINILILEA 233
Query: 437 GQR-------LKICDFGTAAD--KATYMT 496
+ LKI DFG A + K T M+
Sbjct: 234 IENHNLADTVLKITDFGLAREWHKTTKMS 262
Score = 45.2 bits (102), Expect = 2e-04
Identities = 17/36 (47%), Positives = 27/36 (75%)
Frame = +1
Query: 514 AWMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRKPF 621
AWMAPEV S +++ DV+S+G++LWE+L+ P+
Sbjct: 268 AWMAPEVIRLSLFSKSSDVWSFGVLLWELLTGEVPY 303
>BC001401-1|AAH01401.1| 455|Homo sapiens sterile alpha motif and
leucine zipper containing kinase AZK protein.
Length = 455
Score = 62.9 bits (146), Expect = 1e-09
Identities = 29/69 (42%), Positives = 42/69 (60%)
Frame = +2
Query: 266 GSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQR 445
GSLY+ +++ + H M+WA A+G+ YLH P +IHRDLK N+++ G
Sbjct: 88 GSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGV- 146
Query: 446 LKICDFGTA 472
LKICDFG +
Sbjct: 147 LKICDFGAS 155
Score = 51.2 bits (117), Expect = 3e-06
Identities = 18/35 (51%), Positives = 26/35 (74%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRKPF 621
WMAPEV + +E CD +S+G++LWE+L+R PF
Sbjct: 172 WMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPF 206
Score = 34.7 bits (76), Expect = 0.31
Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 2/103 (1%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVW--RNRFVAVKHINSEAEKREFAIEVRQLSRVCHP 194
+I + ++Q G G+FG V++ W +++ VAVK + + EK E LS + H
Sbjct: 10 QIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKL-LKIEK-----EAEILSVLSHR 63
Query: 195 NIVRLYGACTRGAHVCLVMEMQKVALSIMYYTTDPNPNTQQHM 323
NI++ YG + +V E +L +Y + N + + M
Sbjct: 64 NIIQFYGVILEPPNYGIVTEY--ASLGSLYDYINSNRSEEMDM 104
>AF480462-1|AAL85892.1| 455|Homo sapiens mixed lineage
kinase-related kinase MRK-beta protein.
Length = 455
Score = 62.9 bits (146), Expect = 1e-09
Identities = 29/69 (42%), Positives = 42/69 (60%)
Frame = +2
Query: 266 GSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQR 445
GSLY+ +++ + H M+WA A+G+ YLH P +IHRDLK N+++ G
Sbjct: 88 GSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGV- 146
Query: 446 LKICDFGTA 472
LKICDFG +
Sbjct: 147 LKICDFGAS 155
Score = 51.2 bits (117), Expect = 3e-06
Identities = 18/35 (51%), Positives = 26/35 (74%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRKPF 621
WMAPEV + +E CD +S+G++LWE+L+R PF
Sbjct: 172 WMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPF 206
Score = 34.7 bits (76), Expect = 0.31
Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 2/103 (1%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVW--RNRFVAVKHINSEAEKREFAIEVRQLSRVCHP 194
+I + ++Q G G+FG V++ W +++ VAVK + + EK E LS + H
Sbjct: 10 QIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKL-LKIEK-----EAEILSVLSHR 63
Query: 195 NIVRLYGACTRGAHVCLVMEMQKVALSIMYYTTDPNPNTQQHM 323
NI++ YG + +V E +L +Y + N + + M
Sbjct: 64 NIIQFYGVILEPPNYGIVTEY--ASLGSLYDYINSNRSEEMDM 104
>AF480461-1|AAL85891.1| 800|Homo sapiens mixed lineage
kinase-related kinase MRK-alpha protein.
Length = 800
Score = 62.9 bits (146), Expect = 1e-09
Identities = 29/69 (42%), Positives = 42/69 (60%)
Frame = +2
Query: 266 GSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQR 445
GSLY+ +++ + H M+WA A+G+ YLH P +IHRDLK N+++ G
Sbjct: 88 GSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGV- 146
Query: 446 LKICDFGTA 472
LKICDFG +
Sbjct: 147 LKICDFGAS 155
Score = 51.2 bits (117), Expect = 3e-06
Identities = 18/35 (51%), Positives = 26/35 (74%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRKPF 621
WMAPEV + +E CD +S+G++LWE+L+R PF
Sbjct: 172 WMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPF 206
Score = 34.7 bits (76), Expect = 0.31
Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 2/103 (1%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVW--RNRFVAVKHINSEAEKREFAIEVRQLSRVCHP 194
+I + ++Q G G+FG V++ W +++ VAVK + + EK E LS + H
Sbjct: 10 QIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKL-LKIEK-----EAEILSVLSHR 63
Query: 195 NIVRLYGACTRGAHVCLVMEMQKVALSIMYYTTDPNPNTQQHM 323
NI++ YG + +V E +L +Y + N + + M
Sbjct: 64 NIIQFYGVILEPPNYGIVTEY--ASLGSLYDYINSNRSEEMDM 104
>AF465843-1|AAO33376.1| 312|Homo sapiens cervical cancer suppressor
gene-4 protein protein.
Length = 312
Score = 62.9 bits (146), Expect = 1e-09
Identities = 29/69 (42%), Positives = 42/69 (60%)
Frame = +2
Query: 266 GSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQR 445
GSLY+ +++ + H M+WA A+G+ YLH P +IHRDLK N+++ G
Sbjct: 88 GSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGV- 146
Query: 446 LKICDFGTA 472
LKICDFG +
Sbjct: 147 LKICDFGAS 155
Score = 51.2 bits (117), Expect = 3e-06
Identities = 18/35 (51%), Positives = 26/35 (74%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRKPF 621
WMAPEV + +E CD +S+G++LWE+L+R PF
Sbjct: 172 WMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPF 206
Score = 34.7 bits (76), Expect = 0.31
Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 2/103 (1%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVW--RNRFVAVKHINSEAEKREFAIEVRQLSRVCHP 194
+I + ++Q G G+FG V++ W +++ VAVK + + EK E LS + H
Sbjct: 10 QIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKL-LKIEK-----EAEILSVLSHR 63
Query: 195 NIVRLYGACTRGAHVCLVMEMQKVALSIMYYTTDPNPNTQQHM 323
NI++ YG + +V E +L +Y + N + + M
Sbjct: 64 NIIQFYGVILEPPNYGIVTEY--ASLGSLYDYINSNRSEEMDM 104
>AF325454-1|AAK11615.1| 455|Homo sapiens mixed lineage kinase
protein.
Length = 455
Score = 62.9 bits (146), Expect = 1e-09
Identities = 29/69 (42%), Positives = 42/69 (60%)
Frame = +2
Query: 266 GSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQR 445
GSLY+ +++ + H M+WA A+G+ YLH P +IHRDLK N+++ G
Sbjct: 88 GSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGV- 146
Query: 446 LKICDFGTA 472
LKICDFG +
Sbjct: 147 LKICDFGAS 155
Score = 51.2 bits (117), Expect = 3e-06
Identities = 18/35 (51%), Positives = 26/35 (74%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRKPF 621
WMAPEV + +E CD +S+G++LWE+L+R PF
Sbjct: 172 WMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPF 206
Score = 34.7 bits (76), Expect = 0.31
Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 2/103 (1%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVW--RNRFVAVKHINSEAEKREFAIEVRQLSRVCHP 194
+I + ++Q G G+FG V++ W +++ VAVK + + EK E LS + H
Sbjct: 10 QIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKL-LKIEK-----EAEILSVLSHR 63
Query: 195 NIVRLYGACTRGAHVCLVMEMQKVALSIMYYTTDPNPNTQQHM 323
NI++ YG + +V E +L +Y + N + + M
Sbjct: 64 NIIQFYGVILEPPNYGIVTEY--ASLGSLYDYINSNRSEEMDM 104
>AF251441-1|AAF65822.1| 800|Homo sapiens sterile-alpha motif and
leucine zipper containing kinase AZK protein.
Length = 800
Score = 62.9 bits (146), Expect = 1e-09
Identities = 29/69 (42%), Positives = 42/69 (60%)
Frame = +2
Query: 266 GSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQR 445
GSLY+ +++ + H M+WA A+G+ YLH P +IHRDLK N+++ G
Sbjct: 88 GSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGV- 146
Query: 446 LKICDFGTA 472
LKICDFG +
Sbjct: 147 LKICDFGAS 155
Score = 51.2 bits (117), Expect = 3e-06
Identities = 18/35 (51%), Positives = 26/35 (74%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRKPF 621
WMAPEV + +E CD +S+G++LWE+L+R PF
Sbjct: 172 WMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPF 206
Score = 34.7 bits (76), Expect = 0.31
Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 2/103 (1%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVW--RNRFVAVKHINSEAEKREFAIEVRQLSRVCHP 194
+I + ++Q G G+FG V++ W +++ VAVK + + EK E LS + H
Sbjct: 10 QIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKL-LKIEK-----EAEILSVLSHR 63
Query: 195 NIVRLYGACTRGAHVCLVMEMQKVALSIMYYTTDPNPNTQQHM 323
NI++ YG + +V E +L +Y + N + + M
Sbjct: 64 NIIQFYGVILEPPNYGIVTEY--ASLGSLYDYINSNRSEEMDM 104
>AF238255-1|AAF63490.1| 800|Homo sapiens mixed lineage kinase ZAK
protein.
Length = 800
Score = 62.9 bits (146), Expect = 1e-09
Identities = 29/69 (42%), Positives = 42/69 (60%)
Frame = +2
Query: 266 GSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQR 445
GSLY+ +++ + H M+WA A+G+ YLH P +IHRDLK N+++ G
Sbjct: 88 GSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGV- 146
Query: 446 LKICDFGTA 472
LKICDFG +
Sbjct: 147 LKICDFGAS 155
Score = 51.2 bits (117), Expect = 3e-06
Identities = 18/35 (51%), Positives = 26/35 (74%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRKPF 621
WMAPEV + +E CD +S+G++LWE+L+R PF
Sbjct: 172 WMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPF 206
Score = 34.7 bits (76), Expect = 0.31
Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 2/103 (1%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVW--RNRFVAVKHINSEAEKREFAIEVRQLSRVCHP 194
+I + ++Q G G+FG V++ W +++ VAVK + + EK E LS + H
Sbjct: 10 QIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKL-LKIEK-----EAEILSVLSHR 63
Query: 195 NIVRLYGACTRGAHVCLVMEMQKVALSIMYYTTDPNPNTQQHM 323
NI++ YG + +V E +L +Y + N + + M
Sbjct: 64 NIIQFYGVILEPPNYGIVTEY--ASLGSLYDYINSNRSEEMDM 104
>AC013461-1|AAX93067.1| 400|Homo sapiens unknown protein.
Length = 400
Score = 62.9 bits (146), Expect = 1e-09
Identities = 29/69 (42%), Positives = 42/69 (60%)
Frame = +2
Query: 266 GSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQR 445
GSLY+ +++ + H M+WA A+G+ YLH P +IHRDLK N+++ G
Sbjct: 35 GSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGV- 93
Query: 446 LKICDFGTA 472
LKICDFG +
Sbjct: 94 LKICDFGAS 102
Score = 51.2 bits (117), Expect = 3e-06
Identities = 18/35 (51%), Positives = 26/35 (74%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRKPF 621
WMAPEV + +E CD +S+G++LWE+L+R PF
Sbjct: 119 WMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPF 153
>AB208974-1|BAD92211.1| 845|Homo sapiens Plaucible mixed-lineage
kinase protein variant protein.
Length = 845
Score = 62.9 bits (146), Expect = 1e-09
Identities = 29/69 (42%), Positives = 42/69 (60%)
Frame = +2
Query: 266 GSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQR 445
GSLY+ +++ + H M+WA A+G+ YLH P +IHRDLK N+++ G
Sbjct: 133 GSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGV- 191
Query: 446 LKICDFGTA 472
LKICDFG +
Sbjct: 192 LKICDFGAS 200
Score = 51.2 bits (117), Expect = 3e-06
Identities = 18/35 (51%), Positives = 26/35 (74%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRKPF 621
WMAPEV + +E CD +S+G++LWE+L+R PF
Sbjct: 217 WMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPF 251
Score = 34.7 bits (76), Expect = 0.31
Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 2/103 (1%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVW--RNRFVAVKHINSEAEKREFAIEVRQLSRVCHP 194
+I + ++Q G G+FG V++ W +++ VAVK + + EK E LS + H
Sbjct: 55 QIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKL-LKIEK-----EAEILSVLSHR 108
Query: 195 NIVRLYGACTRGAHVCLVMEMQKVALSIMYYTTDPNPNTQQHM 323
NI++ YG + +V E +L +Y + N + + M
Sbjct: 109 NIIQFYGVILEPPNYGIVTEY--ASLGSLYDYINSNRSEEMDM 149
>AB049734-1|BAB16445.1| 455|Homo sapiens MLTK-beta protein.
Length = 455
Score = 62.9 bits (146), Expect = 1e-09
Identities = 29/69 (42%), Positives = 42/69 (60%)
Frame = +2
Query: 266 GSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQR 445
GSLY+ +++ + H M+WA A+G+ YLH P +IHRDLK N+++ G
Sbjct: 88 GSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGV- 146
Query: 446 LKICDFGTA 472
LKICDFG +
Sbjct: 147 LKICDFGAS 155
Score = 51.2 bits (117), Expect = 3e-06
Identities = 18/35 (51%), Positives = 26/35 (74%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRKPF 621
WMAPEV + +E CD +S+G++LWE+L+R PF
Sbjct: 172 WMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPF 206
Score = 34.7 bits (76), Expect = 0.31
Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 2/103 (1%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVW--RNRFVAVKHINSEAEKREFAIEVRQLSRVCHP 194
+I + ++Q G G+FG V++ W +++ VAVK + + EK E LS + H
Sbjct: 10 QIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKL-LKIEK-----EAEILSVLSHR 63
Query: 195 NIVRLYGACTRGAHVCLVMEMQKVALSIMYYTTDPNPNTQQHM 323
NI++ YG + +V E +L +Y + N + + M
Sbjct: 64 NIIQFYGVILEPPNYGIVTEY--ASLGSLYDYINSNRSEEMDM 104
>AB049733-1|BAB16444.1| 800|Homo sapiens MLTK-alpha protein.
Length = 800
Score = 62.9 bits (146), Expect = 1e-09
Identities = 29/69 (42%), Positives = 42/69 (60%)
Frame = +2
Query: 266 GSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQR 445
GSLY+ +++ + H M+WA A+G+ YLH P +IHRDLK N+++ G
Sbjct: 88 GSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGV- 146
Query: 446 LKICDFGTA 472
LKICDFG +
Sbjct: 147 LKICDFGAS 155
Score = 51.2 bits (117), Expect = 3e-06
Identities = 18/35 (51%), Positives = 26/35 (74%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRKPF 621
WMAPEV + +E CD +S+G++LWE+L+R PF
Sbjct: 172 WMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPF 206
Score = 34.7 bits (76), Expect = 0.31
Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 2/103 (1%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVW--RNRFVAVKHINSEAEKREFAIEVRQLSRVCHP 194
+I + ++Q G G+FG V++ W +++ VAVK + + EK E LS + H
Sbjct: 10 QIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKL-LKIEK-----EAEILSVLSHR 63
Query: 195 NIVRLYGACTRGAHVCLVMEMQKVALSIMYYTTDPNPNTQQHM 323
NI++ YG + +V E +L +Y + N + + M
Sbjct: 64 NIIQFYGVILEPPNYGIVTEY--ASLGSLYDYINSNRSEEMDM 104
>AB030034-1|BAB12040.1| 800|Homo sapiens plaucible mixed-lineage
kinase protein protein.
Length = 800
Score = 62.9 bits (146), Expect = 1e-09
Identities = 29/69 (42%), Positives = 42/69 (60%)
Frame = +2
Query: 266 GSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQR 445
GSLY+ +++ + H M+WA A+G+ YLH P +IHRDLK N+++ G
Sbjct: 88 GSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGV- 146
Query: 446 LKICDFGTA 472
LKICDFG +
Sbjct: 147 LKICDFGAS 155
Score = 51.2 bits (117), Expect = 3e-06
Identities = 18/35 (51%), Positives = 26/35 (74%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRKPF 621
WMAPEV + +E CD +S+G++LWE+L+R PF
Sbjct: 172 WMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPF 206
Score = 34.7 bits (76), Expect = 0.31
Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 2/103 (1%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVW--RNRFVAVKHINSEAEKREFAIEVRQLSRVCHP 194
+I + ++Q G G+FG V++ W +++ VAVK + + EK E LS + H
Sbjct: 10 QIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKL-LKIEK-----EAEILSVLSHR 63
Query: 195 NIVRLYGACTRGAHVCLVMEMQKVALSIMYYTTDPNPNTQQHM 323
NI++ YG + +V E +L +Y + N + + M
Sbjct: 64 NIIQFYGVILEPPNYGIVTEY--ASLGSLYDYINSNRSEEMDM 104
>S65186-1|AAB28072.2| 620|Homo sapiens EMT protein.
Length = 620
Score = 60.9 bits (141), Expect = 4e-09
Identities = 32/82 (39%), Positives = 45/82 (54%), Gaps = 2/82 (2%)
Frame = +3
Query: 24 IDYSEIQELSVVGKGAFGVVWKGVWRNRF-VAVKHINSEAEKRE-FAIEVRQLSRVCHPN 197
ID SE+ + +G G FG+V G W N+ VA+K I A E F E + ++ HP
Sbjct: 358 IDPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIREGAMSEEDFIEEAEVMMKLSHPK 417
Query: 198 IVRLYGACTRGAHVCLVMEMQK 263
+V+LYG C A +CLV E +
Sbjct: 418 LVQLYGVCLEQAPICLVFEFME 439
Score = 44.8 bits (101), Expect = 3e-04
Identities = 17/33 (51%), Positives = 24/33 (72%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRK 615
W +PEVF S Y+ K DV+S+G+++WEV S K
Sbjct: 524 WASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGK 556
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/69 (34%), Positives = 33/69 (47%)
Frame = +2
Query: 260 EGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGG 439
E G L + L + + + A + EG+AYL +IHRDL N L VG
Sbjct: 439 EHGCLSDYLRTQ-RGLFAAETLLGMCLDVCEGMAYLEEAC---VIHRDLAARNCL-VGEN 493
Query: 440 QRLKICDFG 466
Q +K+ DFG
Sbjct: 494 QVIKVSDFG 502
>L10717-1|AAA36748.1| 620|Homo sapiens tyrosine kinase protein.
Length = 620
Score = 60.9 bits (141), Expect = 4e-09
Identities = 32/82 (39%), Positives = 45/82 (54%), Gaps = 2/82 (2%)
Frame = +3
Query: 24 IDYSEIQELSVVGKGAFGVVWKGVWRNRF-VAVKHINSEAEKRE-FAIEVRQLSRVCHPN 197
ID SE+ + +G G FG+V G W N+ VA+K I A E F E + ++ HP
Sbjct: 358 IDPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIREGAMSEEDFIEEAEVMMKLSHPK 417
Query: 198 IVRLYGACTRGAHVCLVMEMQK 263
+V+LYG C A +CLV E +
Sbjct: 418 LVQLYGVCLEQAPICLVFEFME 439
Score = 44.8 bits (101), Expect = 3e-04
Identities = 17/33 (51%), Positives = 24/33 (72%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRK 615
W +PEVF S Y+ K DV+S+G+++WEV S K
Sbjct: 524 WASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGK 556
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/69 (34%), Positives = 33/69 (47%)
Frame = +2
Query: 260 EGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGG 439
E G L + L + + + A + EG+AYL +IHRDL N L VG
Sbjct: 439 EHGCLSDYLRTQ-RGLFAAETLLGMCLDVCEGMAYLEEAC---VIHRDLAARNCL-VGEN 493
Query: 440 QRLKICDFG 466
Q +K+ DFG
Sbjct: 494 QVIKVSDFG 502
>D13720-1|BAA02873.1| 620|Homo sapiens ITK protein.
Length = 620
Score = 60.9 bits (141), Expect = 4e-09
Identities = 32/82 (39%), Positives = 45/82 (54%), Gaps = 2/82 (2%)
Frame = +3
Query: 24 IDYSEIQELSVVGKGAFGVVWKGVWRNRF-VAVKHINSEAEKRE-FAIEVRQLSRVCHPN 197
ID SE+ + +G G FG+V G W N+ VA+K I A E F E + ++ HP
Sbjct: 358 IDPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIREGAMSEEDFIEEAEVMMKLSHPK 417
Query: 198 IVRLYGACTRGAHVCLVMEMQK 263
+V+LYG C A +CLV E +
Sbjct: 418 LVQLYGVCLEQAPICLVFEFME 439
Score = 44.8 bits (101), Expect = 3e-04
Identities = 17/33 (51%), Positives = 24/33 (72%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRK 615
W +PEVF S Y+ K DV+S+G+++WEV S K
Sbjct: 524 WASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGK 556
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/69 (34%), Positives = 33/69 (47%)
Frame = +2
Query: 260 EGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGG 439
E G L + L + + + A + EG+AYL +IHRDL N L VG
Sbjct: 439 EHGCLSDYLRTQ-RGLFAAETLLGMCLDVCEGMAYLEEAC---VIHRDLAARNCL-VGEN 493
Query: 440 QRLKICDFG 466
Q +K+ DFG
Sbjct: 494 QVIKVSDFG 502
>BC109078-1|AAI09079.1| 620|Homo sapiens IL2-inducible T-cell
kinase protein.
Length = 620
Score = 60.9 bits (141), Expect = 4e-09
Identities = 32/82 (39%), Positives = 45/82 (54%), Gaps = 2/82 (2%)
Frame = +3
Query: 24 IDYSEIQELSVVGKGAFGVVWKGVWRNRF-VAVKHINSEAEKRE-FAIEVRQLSRVCHPN 197
ID SE+ + +G G FG+V G W N+ VA+K I A E F E + ++ HP
Sbjct: 358 IDPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIREGAMSEEDFIEEAEVMMKLSHPK 417
Query: 198 IVRLYGACTRGAHVCLVMEMQK 263
+V+LYG C A +CLV E +
Sbjct: 418 LVQLYGVCLEQAPICLVFEFME 439
Score = 44.8 bits (101), Expect = 3e-04
Identities = 17/33 (51%), Positives = 24/33 (72%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRK 615
W +PEVF S Y+ K DV+S+G+++WEV S K
Sbjct: 524 WASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGK 556
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/69 (34%), Positives = 33/69 (47%)
Frame = +2
Query: 260 EGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGG 439
E G L + L + + + A + EG+AYL +IHRDL N L VG
Sbjct: 439 EHGCLSDYLRTQ-RGLFAAETLLGMCLDVCEGMAYLEEAC---VIHRDLAARNCL-VGEN 493
Query: 440 QRLKICDFG 466
Q +K+ DFG
Sbjct: 494 QVIKVSDFG 502
>BC109077-1|AAI09078.1| 620|Homo sapiens IL2-inducible T-cell
kinase protein.
Length = 620
Score = 60.9 bits (141), Expect = 4e-09
Identities = 32/82 (39%), Positives = 45/82 (54%), Gaps = 2/82 (2%)
Frame = +3
Query: 24 IDYSEIQELSVVGKGAFGVVWKGVWRNRF-VAVKHINSEAEKRE-FAIEVRQLSRVCHPN 197
ID SE+ + +G G FG+V G W N+ VA+K I A E F E + ++ HP
Sbjct: 358 IDPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIREGAMSEEDFIEEAEVMMKLSHPK 417
Query: 198 IVRLYGACTRGAHVCLVMEMQK 263
+V+LYG C A +CLV E +
Sbjct: 418 LVQLYGVCLEQAPICLVFEFME 439
Score = 44.8 bits (101), Expect = 3e-04
Identities = 17/33 (51%), Positives = 24/33 (72%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRK 615
W +PEVF S Y+ K DV+S+G+++WEV S K
Sbjct: 524 WASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGK 556
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/69 (34%), Positives = 33/69 (47%)
Frame = +2
Query: 260 EGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGG 439
E G L + L + + + A + EG+AYL +IHRDL N L VG
Sbjct: 439 EHGCLSDYLRTQ-RGLFAAETLLGMCLDVCEGMAYLEEAC---VIHRDLAARNCL-VGEN 493
Query: 440 QRLKICDFG 466
Q +K+ DFG
Sbjct: 494 QVIKVSDFG 502
>U22322-1|AAC50116.1| 505|Homo sapiens Rak protein.
Length = 505
Score = 58.0 bits (134), Expect = 3e-08
Identities = 28/83 (33%), Positives = 46/83 (55%), Gaps = 2/83 (2%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRF-VAVKHIN-SEAEKREFAIEVRQLSRVCHP 194
EID + IQ L +G G FG VW+G+W N VAVK + + +F E + + + HP
Sbjct: 228 EIDRNSIQLLKRLGSGQFGEVWEGLWNNTTPVAVKTLKPGSMDPNDFLREAQIMKNLRHP 287
Query: 195 NIVRLYGACTRGAHVCLVMEMQK 263
+++LY CT + ++ E+ +
Sbjct: 288 KLIQLYAVCTLEDPIYIITELMR 310
Score = 40.7 bits (91), Expect = 0.005
Identities = 28/69 (40%), Positives = 33/69 (47%)
Frame = +2
Query: 266 GSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQR 445
GSL L N K + A Q A G+AYL S + IHRDL N +LVG
Sbjct: 312 GSLQEYLQNDTGSKIHLTQQVDMAAQVASGMAYLES---RNYIHRDLAARN-VLVGEHNI 367
Query: 446 LKICDFGTA 472
K+ DFG A
Sbjct: 368 YKVADFGLA 376
Score = 35.1 bits (77), Expect = 0.23
Identities = 13/33 (39%), Positives = 23/33 (69%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRK 615
W APE + ++ K DV+S+GI+L+E+++ K
Sbjct: 399 WTAPEAIRSNKFSIKSDVWSFGILLYEIITYGK 431
>U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase
protein.
Length = 505
Score = 58.0 bits (134), Expect = 3e-08
Identities = 28/83 (33%), Positives = 46/83 (55%), Gaps = 2/83 (2%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRF-VAVKHIN-SEAEKREFAIEVRQLSRVCHP 194
EID + IQ L +G G FG VW+G+W N VAVK + + +F E + + + HP
Sbjct: 228 EIDRNSIQLLKRLGSGQFGEVWEGLWNNTTPVAVKTLKPGSMDPNDFLREAQIMKNLRHP 287
Query: 195 NIVRLYGACTRGAHVCLVMEMQK 263
+++LY CT + ++ E+ +
Sbjct: 288 KLIQLYAVCTLEDPIYIITELMR 310
Score = 40.7 bits (91), Expect = 0.005
Identities = 28/69 (40%), Positives = 33/69 (47%)
Frame = +2
Query: 266 GSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQR 445
GSL L N K + A Q A G+AYL S + IHRDL N +LVG
Sbjct: 312 GSLQEYLQNDTGSKIHLTQQVDMAAQVASGMAYLES---RNYIHRDLAARN-VLVGEHNI 367
Query: 446 LKICDFGTA 472
K+ DFG A
Sbjct: 368 YKVADFGLA 376
Score = 35.1 bits (77), Expect = 0.23
Identities = 13/33 (39%), Positives = 23/33 (69%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRK 615
W APE + ++ K DV+S+GI+L+E+++ K
Sbjct: 399 WTAPEAIRSNKFSIKSDVWSFGILLYEIITYGK 431
>BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 58.0 bits (134), Expect = 3e-08
Identities = 28/83 (33%), Positives = 46/83 (55%), Gaps = 2/83 (2%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRF-VAVKHIN-SEAEKREFAIEVRQLSRVCHP 194
EID + IQ L +G G FG VW+G+W N VAVK + + +F E + + + HP
Sbjct: 228 EIDRNSIQLLKRLGSGQFGEVWEGLWNNTTPVAVKTLKPGSMDPNDFLREAQIMKNLRHP 287
Query: 195 NIVRLYGACTRGAHVCLVMEMQK 263
+++LY CT + ++ E+ +
Sbjct: 288 KLIQLYAVCTLEDPIYIITELMR 310
Score = 40.7 bits (91), Expect = 0.005
Identities = 28/69 (40%), Positives = 33/69 (47%)
Frame = +2
Query: 266 GSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQR 445
GSL L N K + A Q A G+AYL S + IHRDL N +LVG
Sbjct: 312 GSLQEYLQNDTGSKIHLTQQVDMAAQVASGMAYLES---RNYIHRDLAARN-VLVGEHNI 367
Query: 446 LKICDFGTA 472
K+ DFG A
Sbjct: 368 YKVADFGLA 376
Score = 35.1 bits (77), Expect = 0.23
Identities = 13/33 (39%), Positives = 23/33 (69%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRK 615
W APE + ++ K DV+S+GI+L+E+++ K
Sbjct: 399 WTAPEAIRSNKFSIKSDVWSFGILLYEIITYGK 431
>AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 58.0 bits (134), Expect = 3e-08
Identities = 28/83 (33%), Positives = 46/83 (55%), Gaps = 2/83 (2%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRF-VAVKHIN-SEAEKREFAIEVRQLSRVCHP 194
EID + IQ L +G G FG VW+G+W N VAVK + + +F E + + + HP
Sbjct: 228 EIDRNSIQLLKRLGSGQFGEVWEGLWNNTTPVAVKTLKPGSMDPNDFLREAQIMKNLRHP 287
Query: 195 NIVRLYGACTRGAHVCLVMEMQK 263
+++LY CT + ++ E+ +
Sbjct: 288 KLIQLYAVCTLEDPIYIITELMR 310
Score = 40.7 bits (91), Expect = 0.005
Identities = 28/69 (40%), Positives = 33/69 (47%)
Frame = +2
Query: 266 GSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQR 445
GSL L N K + A Q A G+AYL S + IHRDL N +LVG
Sbjct: 312 GSLQEYLQNDTGSKIHLTQQVDMAAQVASGMAYLES---RNYIHRDLAARN-VLVGEHNI 367
Query: 446 LKICDFGTA 472
K+ DFG A
Sbjct: 368 YKVADFGLA 376
Score = 35.1 bits (77), Expect = 0.23
Identities = 13/33 (39%), Positives = 23/33 (69%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRK 615
W APE + ++ K DV+S+GI+L+E+++ K
Sbjct: 399 WTAPEAIRSNKFSIKSDVWSFGILLYEIITYGK 431
>AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 58.0 bits (134), Expect = 3e-08
Identities = 28/83 (33%), Positives = 46/83 (55%), Gaps = 2/83 (2%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRF-VAVKHIN-SEAEKREFAIEVRQLSRVCHP 194
EID + IQ L +G G FG VW+G+W N VAVK + + +F E + + + HP
Sbjct: 228 EIDRNSIQLLKRLGSGQFGEVWEGLWNNTTPVAVKTLKPGSMDPNDFLREAQIMKNLRHP 287
Query: 195 NIVRLYGACTRGAHVCLVMEMQK 263
+++LY CT + ++ E+ +
Sbjct: 288 KLIQLYAVCTLEDPIYIITELMR 310
Score = 40.7 bits (91), Expect = 0.005
Identities = 28/69 (40%), Positives = 33/69 (47%)
Frame = +2
Query: 266 GSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQR 445
GSL L N K + A Q A G+AYL S + IHRDL N +LVG
Sbjct: 312 GSLQEYLQNDTGSKIHLTQQVDMAAQVASGMAYLES---RNYIHRDLAARN-VLVGEHNI 367
Query: 446 LKICDFGTA 472
K+ DFG A
Sbjct: 368 YKVADFGLA 376
Score = 35.1 bits (77), Expect = 0.23
Identities = 13/33 (39%), Positives = 23/33 (69%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRK 615
W APE + ++ K DV+S+GI+L+E+++ K
Sbjct: 399 WTAPEAIRSNKFSIKSDVWSFGILLYEIITYGK 431
>AB001872-1|BAA24817.1| 966|Homo sapiens leucine zipper bearing
kinase protein.
Length = 966
Score = 58.0 bits (134), Expect = 3e-08
Identities = 29/84 (34%), Positives = 46/84 (54%)
Frame = +3
Query: 3 QQTFVEEIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEKREFAIEVRQLSR 182
QQ E+ + EI EL +G GA G V+ G +R VA+K + + E +++ L +
Sbjct: 156 QQQDTWEVPFEEISELQWLGSGAQGAVFLGKFRAEEVAIKKVREQNE-----TDIKHLRK 210
Query: 183 VCHPNIVRLYGACTRGAHVCLVME 254
+ HPNI+ G CT+ C++ME
Sbjct: 211 LKHPNIIAFKGVCTQAPCYCIIME 234
Score = 50.4 bits (115), Expect = 6e-06
Identities = 35/80 (43%), Positives = 45/80 (56%), Gaps = 3/80 (3%)
Frame = +2
Query: 266 GSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQR 445
G LY VL R K T + W+ A G+ YLH K +IHRDLK PN +LV
Sbjct: 239 GQLYEVL--RAGRKITPRLLVDWSTGIASGMNYLHLHK---IIHRDLKSPN-VLVTHTDA 292
Query: 446 LKICDFGTA---ADKATYMT 496
+KI DFGT+ +DK+T M+
Sbjct: 293 VKISDFGTSKELSDKSTKMS 312
Score = 46.8 bits (106), Expect = 7e-05
Identities = 17/36 (47%), Positives = 26/36 (72%)
Frame = +1
Query: 514 AWMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRKPF 621
AWMAPEV +EK D++S+G++LWE+L+ P+
Sbjct: 318 AWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPY 353
>L76191-1|AAC41949.1| 712|Homo sapiens interleukin-1
receptor-associated kinase protein.
Length = 712
Score = 57.6 bits (133), Expect = 4e-08
Identities = 30/70 (42%), Positives = 38/70 (54%), Gaps = 6/70 (8%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKHINSEAE------KREFAIEVRQLSRVCHPNIVRLYGA 218
+G+G FG V++ V RN AVK + A+ K+ F EV QLSR HPNIV G
Sbjct: 218 IGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGY 277
Query: 219 CTRGAHVCLV 248
C + CLV
Sbjct: 278 CAQNGFYCLV 287
>DQ054788-1|AAY88246.1| 633|Homo sapiens interleukin-1 receptor
associated-kinase 1 splice variant c protein.
Length = 633
Score = 57.6 bits (133), Expect = 4e-08
Identities = 30/70 (42%), Positives = 38/70 (54%), Gaps = 6/70 (8%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKHINSEAE------KREFAIEVRQLSRVCHPNIVRLYGA 218
+G+G FG V++ V RN AVK + A+ K+ F EV QLSR HPNIV G
Sbjct: 218 IGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGY 277
Query: 219 CTRGAHVCLV 248
C + CLV
Sbjct: 278 CAQNGFYCLV 287
>BC054000-1|AAH54000.1| 693|Homo sapiens IRAK1 protein protein.
Length = 693
Score = 57.6 bits (133), Expect = 4e-08
Identities = 30/70 (42%), Positives = 38/70 (54%), Gaps = 6/70 (8%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKHINSEAE------KREFAIEVRQLSRVCHPNIVRLYGA 218
+G+G FG V++ V RN AVK + A+ K+ F EV QLSR HPNIV G
Sbjct: 244 IGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGY 303
Query: 219 CTRGAHVCLV 248
C + CLV
Sbjct: 304 CAQNGFYCLV 313
>BC014963-1|AAH14963.1| 633|Homo sapiens interleukin-1
receptor-associated kinase 1 protein.
Length = 633
Score = 57.6 bits (133), Expect = 4e-08
Identities = 30/70 (42%), Positives = 38/70 (54%), Gaps = 6/70 (8%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKHINSEAE------KREFAIEVRQLSRVCHPNIVRLYGA 218
+G+G FG V++ V RN AVK + A+ K+ F EV QLSR HPNIV G
Sbjct: 218 IGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGY 277
Query: 219 CTRGAHVCLV 248
C + CLV
Sbjct: 278 CAQNGFYCLV 287
>AF346607-1|AAK62888.1| 682|Homo sapiens interleukin-1 receptor
associated kinase 1b protein.
Length = 682
Score = 57.6 bits (133), Expect = 4e-08
Identities = 30/70 (42%), Positives = 38/70 (54%), Gaps = 6/70 (8%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKHINSEAE------KREFAIEVRQLSRVCHPNIVRLYGA 218
+G+G FG V++ V RN AVK + A+ K+ F EV QLSR HPNIV G
Sbjct: 218 IGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGY 277
Query: 219 CTRGAHVCLV 248
C + CLV
Sbjct: 278 CAQNGFYCLV 287
>AF030876-1|AAC08756.1| 712|Homo sapiens Interleukin 1
receptor-associated kinase 1 protein.
Length = 712
Score = 57.6 bits (133), Expect = 4e-08
Identities = 30/70 (42%), Positives = 38/70 (54%), Gaps = 6/70 (8%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKHINSEAE------KREFAIEVRQLSRVCHPNIVRLYGA 218
+G+G FG V++ V RN AVK + A+ K+ F EV QLSR HPNIV G
Sbjct: 218 IGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGY 277
Query: 219 CTRGAHVCLV 248
C + CLV
Sbjct: 278 CAQNGFYCLV 287
>D29767-1|BAA06171.1| 631|Homo sapiens Tec protein-tyrosine kinase
protein.
Length = 631
Score = 57.2 bits (132), Expect = 5e-08
Identities = 30/83 (36%), Positives = 49/83 (59%), Gaps = 2/83 (2%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRF-VAVKHINSEAE-KREFAIEVRQLSRVCHP 194
EI+ SE+ + +G G FGVV G WR ++ VA+K I A + +F E + + ++ HP
Sbjct: 364 EINPSELTFMRELGSGLFGVVRLGKWRAQYKVAIKAIREGAMCEEDFIEEAKVMMKLTHP 423
Query: 195 NIVRLYGACTRGAHVCLVMEMQK 263
+V+LYG CT+ + +V E +
Sbjct: 424 KLVQLYGVCTQQKPIYIVTEFME 446
Score = 42.3 bits (95), Expect = 0.002
Identities = 17/36 (47%), Positives = 25/36 (69%), Gaps = 1/36 (2%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSR-RKPF 621
W PEVF S ++ K DV+S+G+++WEV + R PF
Sbjct: 531 WCPPEVFNYSRFSSKSDVWSFGVLMWEVFTEGRMPF 566
>BC101713-1|AAI01714.1| 631|Homo sapiens tec protein tyrosine
kinase protein.
Length = 631
Score = 57.2 bits (132), Expect = 5e-08
Identities = 30/83 (36%), Positives = 49/83 (59%), Gaps = 2/83 (2%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRF-VAVKHINSEAE-KREFAIEVRQLSRVCHP 194
EI+ SE+ + +G G FGVV G WR ++ VA+K I A + +F E + + ++ HP
Sbjct: 364 EINPSELTFMRELGSGLFGVVRLGKWRAQYKVAIKAIREGAMCEEDFIEEAKVMMKLTHP 423
Query: 195 NIVRLYGACTRGAHVCLVMEMQK 263
+V+LYG CT+ + +V E +
Sbjct: 424 KLVQLYGVCTQQKPIYIVTEFME 446
Score = 42.3 bits (95), Expect = 0.002
Identities = 17/36 (47%), Positives = 25/36 (69%), Gaps = 1/36 (2%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSR-RKPF 621
W PEVF S ++ K DV+S+G+++WEV + R PF
Sbjct: 531 WCPPEVFNYSRFSSKSDVWSFGVLMWEVFTEGRMPF 566
>BC101711-1|AAI01712.1| 631|Homo sapiens tec protein tyrosine
kinase protein.
Length = 631
Score = 57.2 bits (132), Expect = 5e-08
Identities = 30/83 (36%), Positives = 49/83 (59%), Gaps = 2/83 (2%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRF-VAVKHINSEAE-KREFAIEVRQLSRVCHP 194
EI+ SE+ + +G G FGVV G WR ++ VA+K I A + +F E + + ++ HP
Sbjct: 364 EINPSELTFMRELGSGLFGVVRLGKWRAQYKVAIKAIREGAMCEEDFIEEAKVMMKLTHP 423
Query: 195 NIVRLYGACTRGAHVCLVMEMQK 263
+V+LYG CT+ + +V E +
Sbjct: 424 KLVQLYGVCTQQKPIYIVTEFME 446
Score = 42.3 bits (95), Expect = 0.002
Identities = 17/36 (47%), Positives = 25/36 (69%), Gaps = 1/36 (2%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSR-RKPF 621
W PEVF S ++ K DV+S+G+++WEV + R PF
Sbjct: 531 WCPPEVFNYSRFSSKSDVWSFGVLMWEVFTEGRMPF 566
>U34379-1|AAB60412.1| 527|Homo sapiens tyrosine kinase protein.
Length = 527
Score = 56.8 bits (131), Expect = 7e-08
Identities = 30/90 (33%), Positives = 48/90 (53%), Gaps = 2/90 (2%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRF-VAVKHIN-SEAEKREFAIEVRQLSRVCHP 194
EID SE+ + +G G FGVV G WR+ VA+K IN + +F E + + ++ H
Sbjct: 265 EIDPSELAFIKXIGSGQFGVVHLGEWRSHIQVAIKAINEGSMSEEDFIEEAKVMMKLSHS 324
Query: 195 NIVRLYGACTRGAHVCLVMEMQKVALSIMY 284
+V+LYG C + + +V E + + Y
Sbjct: 325 KLVQLYGVCIQRKPLYIVTEFMENGCLLNY 354
Score = 41.1 bits (92), Expect = 0.004
Identities = 17/36 (47%), Positives = 25/36 (69%), Gaps = 1/36 (2%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRK-PF 621
W PEVF + Y+ K DV+S+G+++WEV + K PF
Sbjct: 432 WSPPEVFLFNKYSSKSDVWSFGVLMWEVFTEGKMPF 467
>L27071-1|AAA74557.1| 527|Homo sapiens tyrosine kinase protein.
Length = 527
Score = 56.4 bits (130), Expect = 9e-08
Identities = 30/90 (33%), Positives = 48/90 (53%), Gaps = 2/90 (2%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRF-VAVKHIN-SEAEKREFAIEVRQLSRVCHP 194
EID SE+ + +G G FGVV G WR+ VA+K IN + +F E + + ++ H
Sbjct: 265 EIDPSELAFIKEIGSGQFGVVHLGEWRSHIQVAIKAINEGSMSEEDFIEEAKVMMKLSHS 324
Query: 195 NIVRLYGACTRGAHVCLVMEMQKVALSIMY 284
+V+LYG C + + +V E + + Y
Sbjct: 325 KLVQLYGVCIQRKPLYIVTEFMENGCLLNY 354
Score = 41.1 bits (92), Expect = 0.004
Identities = 17/36 (47%), Positives = 25/36 (69%), Gaps = 1/36 (2%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRK-PF 621
W PEVF + Y+ K DV+S+G+++WEV + K PF
Sbjct: 432 WSPPEVFLFNKYSSKSDVWSFGVLMWEVFTEGKMPF 467
>U07747-1|AAA19647.1| 847|Homo sapiens serine/threonine protein
kinase protein.
Length = 847
Score = 54.8 bits (126), Expect = 3e-07
Identities = 31/85 (36%), Positives = 45/85 (52%), Gaps = 6/85 (7%)
Frame = +3
Query: 18 EEIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEK--REFAIEVRQLSR--- 182
E + E++ V+G G FG V++G WR VAVK + ++ A VRQ +R
Sbjct: 110 EVASFQELRLEEVIGIGGFGKVYRGSWRGELVAVKAARQDPDEDISVTAESVRQEARLFA 169
Query: 183 -VCHPNIVRLYGACTRGAHVCLVME 254
+ HPNI+ L C ++CLVME
Sbjct: 170 MLAHPNIIALKAVCLEEPNLCLVME 194
Score = 48.8 bits (111), Expect = 2e-05
Identities = 18/36 (50%), Positives = 29/36 (80%)
Frame = +1
Query: 514 AWMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRKPF 621
AWMAPEV + ST+++ DV+S+G++LWE+L+ P+
Sbjct: 287 AWMAPEVIKASTFSKGSDVWSFGVLLWELLTGEVPY 322
Score = 48.0 bits (109), Expect = 3e-05
Identities = 35/89 (39%), Positives = 45/89 (50%), Gaps = 9/89 (10%)
Frame = +2
Query: 257 AEGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVG- 433
A GG L L R P + ++WA Q A G+ YLH P+IHRDLK N+LL+
Sbjct: 196 AAGGPLSRALAGRRVPPHVL---VNWAVQIARGMHYLHCEALVPVIHRDLKSNNILLLQP 252
Query: 434 ------GGQRLKICDFGTAAD--KATYMT 496
+ LKI DFG A + K T M+
Sbjct: 253 IESDDMEHKTLKITDFGLAREWHKTTQMS 281
>L32976-1|AAA59859.1| 847|Homo sapiens protein kinase protein.
Length = 847
Score = 54.8 bits (126), Expect = 3e-07
Identities = 31/85 (36%), Positives = 45/85 (52%), Gaps = 6/85 (7%)
Frame = +3
Query: 18 EEIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEK--REFAIEVRQLSR--- 182
E + E++ V+G G FG V++G WR VAVK + ++ A VRQ +R
Sbjct: 110 EVASFQELRLEEVIGIGGFGKVYRGSWRGELVAVKAARQDPDEDISVTAESVRQEARLFA 169
Query: 183 -VCHPNIVRLYGACTRGAHVCLVME 254
+ HPNI+ L C ++CLVME
Sbjct: 170 MLAHPNIIALKAVCLEEPNLCLVME 194
Score = 48.8 bits (111), Expect = 2e-05
Identities = 18/36 (50%), Positives = 29/36 (80%)
Frame = +1
Query: 514 AWMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRKPF 621
AWMAPEV + ST+++ DV+S+G++LWE+L+ P+
Sbjct: 287 AWMAPEVIKASTFSKGSDVWSFGVLLWELLTGEVPY 322
Score = 48.0 bits (109), Expect = 3e-05
Identities = 35/89 (39%), Positives = 45/89 (50%), Gaps = 9/89 (10%)
Frame = +2
Query: 257 AEGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVG- 433
A GG L L R P + ++WA Q A G+ YLH P+IHRDLK N+LL+
Sbjct: 196 AAGGPLSRALAGRRVPPHVL---VNWAVQIARGMHYLHCEALVPVIHRDLKSNNILLLQP 252
Query: 434 ------GGQRLKICDFGTAAD--KATYMT 496
+ LKI DFG A + K T M+
Sbjct: 253 IESDDMEHKTLKITDFGLAREWHKTTQMS 281
>BC064543-1|AAH64543.1| 847|Homo sapiens mitogen-activated protein
kinase kinase kinase 11 protein.
Length = 847
Score = 54.8 bits (126), Expect = 3e-07
Identities = 31/85 (36%), Positives = 45/85 (52%), Gaps = 6/85 (7%)
Frame = +3
Query: 18 EEIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEK--REFAIEVRQLSR--- 182
E + E++ V+G G FG V++G WR VAVK + ++ A VRQ +R
Sbjct: 110 EVASFQELRLEEVIGIGGFGKVYRGSWRGELVAVKAARQDPDEDISVTAESVRQEARLFA 169
Query: 183 -VCHPNIVRLYGACTRGAHVCLVME 254
+ HPNI+ L C ++CLVME
Sbjct: 170 MLAHPNIIALKAVCLEEPNLCLVME 194
Score = 48.8 bits (111), Expect = 2e-05
Identities = 18/36 (50%), Positives = 29/36 (80%)
Frame = +1
Query: 514 AWMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRKPF 621
AWMAPEV + ST+++ DV+S+G++LWE+L+ P+
Sbjct: 287 AWMAPEVIKASTFSKGSDVWSFGVLLWELLTGEVPY 322
Score = 48.0 bits (109), Expect = 3e-05
Identities = 35/89 (39%), Positives = 45/89 (50%), Gaps = 9/89 (10%)
Frame = +2
Query: 257 AEGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVG- 433
A GG L L R P + ++WA Q A G+ YLH P+IHRDLK N+LL+
Sbjct: 196 AAGGPLSRALAGRRVPPHVL---VNWAVQIARGMHYLHCEALVPVIHRDLKSNNILLLQH 252
Query: 434 ------GGQRLKICDFGTAAD--KATYMT 496
+ LKI DFG A + K T M+
Sbjct: 253 IESDDMEHKTLKITDFGLAREWHKTTQMS 281
>BC011263-1|AAH11263.1| 847|Homo sapiens mitogen-activated protein
kinase kinase kinase 11 protein.
Length = 847
Score = 54.8 bits (126), Expect = 3e-07
Identities = 31/85 (36%), Positives = 45/85 (52%), Gaps = 6/85 (7%)
Frame = +3
Query: 18 EEIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEK--REFAIEVRQLSR--- 182
E + E++ V+G G FG V++G WR VAVK + ++ A VRQ +R
Sbjct: 110 EVASFQELRLEEVIGIGGFGKVYRGSWRGELVAVKAARQDPDEDISVTAESVRQEARLFA 169
Query: 183 -VCHPNIVRLYGACTRGAHVCLVME 254
+ HPNI+ L C ++CLVME
Sbjct: 170 MLAHPNIIALKAVCLEEPNLCLVME 194
Score = 48.8 bits (111), Expect = 2e-05
Identities = 18/36 (50%), Positives = 29/36 (80%)
Frame = +1
Query: 514 AWMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRKPF 621
AWMAPEV + ST+++ DV+S+G++LWE+L+ P+
Sbjct: 287 AWMAPEVIKASTFSKGSDVWSFGVLLWELLTGEVPY 322
Score = 48.0 bits (109), Expect = 3e-05
Identities = 35/89 (39%), Positives = 45/89 (50%), Gaps = 9/89 (10%)
Frame = +2
Query: 257 AEGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVG- 433
A GG L L R P + ++WA Q A G+ YLH P+IHRDLK N+LL+
Sbjct: 196 AAGGPLSRALAGRRVPPHVL---VNWAVQIARGMHYLHCEALVPVIHRDLKSNNILLLQP 252
Query: 434 ------GGQRLKICDFGTAAD--KATYMT 496
+ LKI DFG A + K T M+
Sbjct: 253 IESDDMEHKTLKITDFGLAREWHKTTQMS 281
>AL133380-4|CAI23046.1| 1036|Homo sapiens mixed lineage kinase 4
(KIAA1804) protein.
Length = 1036
Score = 54.8 bits (126), Expect = 3e-07
Identities = 29/82 (35%), Positives = 45/82 (54%), Gaps = 6/82 (7%)
Frame = +3
Query: 36 EIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEKREFAI------EVRQLSRVCHPN 197
E++EL +G G FG V++ W+ + VAVK + E+ A E R + + HPN
Sbjct: 125 ELKEL--IGAGGFGQVYRATWQGQEVAVKAARQDPEQDAAAAAESVRREARLFAMLRHPN 182
Query: 198 IVRLYGACTRGAHVCLVMEMQK 263
I+ L G C + H+CLV+E +
Sbjct: 183 IIELRGVCLQQPHLCLVLEFAR 204
Score = 46.4 bits (105), Expect = 9e-05
Identities = 16/36 (44%), Positives = 28/36 (77%)
Frame = +1
Query: 514 AWMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRKPF 621
AWMAPEV + S +++ D++S+G++LWE+L+ P+
Sbjct: 309 AWMAPEVIKSSLFSKGSDIWSYGVLLWELLTGEVPY 344
Score = 44.0 bits (99), Expect = 5e-04
Identities = 24/58 (41%), Positives = 33/58 (56%), Gaps = 7/58 (12%)
Frame = +2
Query: 326 MSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGG-------GQRLKICDFGTAAD 478
++WA Q A G+ YLH P++HRDLK N+LL+ + LKI DFG A +
Sbjct: 238 VNWAVQIARGMLYLHEEAFVPILHRDLKSSNILLLEKIEHDDICNKTLKITDFGLARE 295
>AL133380-3|CAI23045.1| 570|Homo sapiens mixed lineage kinase 4
(KIAA1804) protein.
Length = 570
Score = 54.8 bits (126), Expect = 3e-07
Identities = 29/82 (35%), Positives = 45/82 (54%), Gaps = 6/82 (7%)
Frame = +3
Query: 36 EIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEKREFAI------EVRQLSRVCHPN 197
E++EL +G G FG V++ W+ + VAVK + E+ A E R + + HPN
Sbjct: 125 ELKEL--IGAGGFGQVYRATWQGQEVAVKAARQDPEQDAAAAAESVRREARLFAMLRHPN 182
Query: 198 IVRLYGACTRGAHVCLVMEMQK 263
I+ L G C + H+CLV+E +
Sbjct: 183 IIELRGVCLQQPHLCLVLEFAR 204
Score = 46.4 bits (105), Expect = 9e-05
Identities = 16/36 (44%), Positives = 28/36 (77%)
Frame = +1
Query: 514 AWMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRKPF 621
AWMAPEV + S +++ D++S+G++LWE+L+ P+
Sbjct: 309 AWMAPEVIKSSLFSKGSDIWSYGVLLWELLTGEVPY 344
Score = 44.0 bits (99), Expect = 5e-04
Identities = 24/58 (41%), Positives = 33/58 (56%), Gaps = 7/58 (12%)
Frame = +2
Query: 326 MSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGG-------GQRLKICDFGTAAD 478
++WA Q A G+ YLH P++HRDLK N+LL+ + LKI DFG A +
Sbjct: 238 VNWAVQIARGMLYLHEEAFVPILHRDLKSSNILLLEKIEHDDICNKTLKITDFGLARE 295
>AK222781-1|BAD96501.1| 847|Homo sapiens mitogen-activated protein
kinase kinase kinase 11 variant protein.
Length = 847
Score = 54.8 bits (126), Expect = 3e-07
Identities = 31/85 (36%), Positives = 45/85 (52%), Gaps = 6/85 (7%)
Frame = +3
Query: 18 EEIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEK--REFAIEVRQLSR--- 182
E + E++ V+G G FG V++G WR VAVK + ++ A VRQ +R
Sbjct: 110 EVASFQELRLEEVIGIGGFGKVYRGSWRGELVAVKAARQDPDEDISVTAESVRQEARLFA 169
Query: 183 -VCHPNIVRLYGACTRGAHVCLVME 254
+ HPNI+ L C ++CLVME
Sbjct: 170 MLAHPNIIALKAVCLEEPNLCLVME 194
Score = 48.8 bits (111), Expect = 2e-05
Identities = 18/36 (50%), Positives = 29/36 (80%)
Frame = +1
Query: 514 AWMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRKPF 621
AWMAPEV + ST+++ DV+S+G++LWE+L+ P+
Sbjct: 287 AWMAPEVIKASTFSKGSDVWSFGVLLWELLTGEVPY 322
Score = 48.0 bits (109), Expect = 3e-05
Identities = 35/89 (39%), Positives = 45/89 (50%), Gaps = 9/89 (10%)
Frame = +2
Query: 257 AEGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVG- 433
A GG L L R P + ++WA Q A G+ YLH P+IHRDLK N+LL+
Sbjct: 196 AAGGPLSRALAGRRVPPHVL---VNWAVQIARGMHYLHCEALVPVIHRDLKSNNILLLQP 252
Query: 434 ------GGQRLKICDFGTAAD--KATYMT 496
+ LKI DFG A + K T M+
Sbjct: 253 IESDDMEHKTLKITDFGLAREWHKTTQMS 281
>AJ311798-1|CAC84640.1| 1036|Homo sapiens mixed lineage kinase 4beta
protein.
Length = 1036
Score = 54.8 bits (126), Expect = 3e-07
Identities = 29/82 (35%), Positives = 45/82 (54%), Gaps = 6/82 (7%)
Frame = +3
Query: 36 EIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEKREFAI------EVRQLSRVCHPN 197
E++EL +G G FG V++ W+ + VAVK + E+ A E R + + HPN
Sbjct: 125 ELKEL--IGAGGFGQVYRATWQGQEVAVKAARQDPEQDAAAAAESVRREARLFAMLRHPN 182
Query: 198 IVRLYGACTRGAHVCLVMEMQK 263
I+ L G C + H+CLV+E +
Sbjct: 183 IIELRGVCLQQPHLCLVLEFAR 204
Score = 44.8 bits (101), Expect = 3e-04
Identities = 16/36 (44%), Positives = 27/36 (75%)
Frame = +1
Query: 514 AWMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRKPF 621
AWMAPEV + S +++ D++S G++LWE+L+ P+
Sbjct: 309 AWMAPEVIKSSLFSKGSDIWSCGVLLWELLTGEVPY 344
Score = 44.0 bits (99), Expect = 5e-04
Identities = 24/58 (41%), Positives = 33/58 (56%), Gaps = 7/58 (12%)
Frame = +2
Query: 326 MSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGG-------GQRLKICDFGTAAD 478
++WA Q A G+ YLH P++HRDLK N+LL+ + LKI DFG A +
Sbjct: 238 VNWAVQIARGMLYLHEEAFVPILHRDLKSSNILLLEEIEHDDICNKTLKITDFGLARE 295
>AJ311797-1|CAC84639.1| 570|Homo sapiens mixed lineage kinase
4alpha protein.
Length = 570
Score = 54.8 bits (126), Expect = 3e-07
Identities = 29/82 (35%), Positives = 45/82 (54%), Gaps = 6/82 (7%)
Frame = +3
Query: 36 EIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEKREFAI------EVRQLSRVCHPN 197
E++EL +G G FG V++ W+ + VAVK + E+ A E R + + HPN
Sbjct: 125 ELKEL--IGAGGFGQVYRATWQGQEVAVKAARQDPEQDAAAAAESVRREARLFAMLRHPN 182
Query: 198 IVRLYGACTRGAHVCLVMEMQK 263
I+ L G C + H+CLV+E +
Sbjct: 183 IIELRGVCLQQPHLCLVLEFAR 204
Score = 44.8 bits (101), Expect = 3e-04
Identities = 16/36 (44%), Positives = 27/36 (75%)
Frame = +1
Query: 514 AWMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRKPF 621
AWMAPEV + S +++ D++S G++LWE+L+ P+
Sbjct: 309 AWMAPEVIKSSLFSKGSDIWSCGVLLWELLTGEVPY 344
Score = 44.0 bits (99), Expect = 5e-04
Identities = 24/58 (41%), Positives = 33/58 (56%), Gaps = 7/58 (12%)
Frame = +2
Query: 326 MSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGG-------GQRLKICDFGTAAD 478
++WA Q A G+ YLH P++HRDLK N+LL+ + LKI DFG A +
Sbjct: 238 VNWAVQIARGMLYLHEEAFVPILHRDLKSSNILLLEEIEHDDICNKTLKITDFGLARE 295
>AB209655-1|BAD92892.1| 310|Homo sapiens mitogen-activated protein
kinase kinase kinase 11 variant protein.
Length = 310
Score = 54.8 bits (126), Expect = 3e-07
Identities = 31/85 (36%), Positives = 45/85 (52%), Gaps = 6/85 (7%)
Frame = +3
Query: 18 EEIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEK--REFAIEVRQLSR--- 182
E + E++ V+G G FG V++G WR VAVK + ++ A VRQ +R
Sbjct: 148 EVASFQELRLEEVIGIGGFGKVYRGSWRGELVAVKAARQDPDEDISVTAESVRQEARLFA 207
Query: 183 -VCHPNIVRLYGACTRGAHVCLVME 254
+ HPNI+ L C ++CLVME
Sbjct: 208 MLAHPNIIALKAVCLEEPNLCLVME 232
Score = 41.5 bits (93), Expect = 0.003
Identities = 24/59 (40%), Positives = 30/59 (50%)
Frame = +2
Query: 257 AEGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVG 433
A GG L L R P + ++WA Q A G+ YLH P+IHRDLK N +G
Sbjct: 234 AAGGPLSRALAGRRVPPHVL---VNWAVQIARGMHYLHCEALVPVIHRDLKSNNSEFLG 289
>L40636-1|AAB08520.1| 984|Homo sapiens protein tyrosine kinase
protein.
Length = 984
Score = 54.4 bits (125), Expect = 4e-07
Identities = 32/92 (34%), Positives = 50/92 (54%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVW-----RNRFVAVKHIN---SEAEKREFAIEV 167
F +EID S ++ V+G G FG V+KG R +VA+K + SE ++R+F E
Sbjct: 610 FAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEA 669
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPNI+RL G T+ V ++ E +
Sbjct: 670 SIMGQFDHPNIIRLEGVVTKSRPVMIITEFME 701
Score = 37.9 bits (84), Expect = 0.033
Identities = 14/30 (46%), Positives = 20/30 (66%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE +T DV+S+GI++WEV+S
Sbjct: 790 WTAPEAIAYRKFTSASDVWSYGIVMWEVMS 819
>BC111744-1|AAI11745.1| 984|Homo sapiens EPH receptor B1 protein.
Length = 984
Score = 54.4 bits (125), Expect = 4e-07
Identities = 32/92 (34%), Positives = 50/92 (54%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVW-----RNRFVAVKHIN---SEAEKREFAIEV 167
F +EID S ++ V+G G FG V+KG R +VA+K + SE ++R+F E
Sbjct: 610 FAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEA 669
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPNI+RL G T+ V ++ E +
Sbjct: 670 SIMGQFDHPNIIRLEGVVTKSRPVMIITEFME 701
Score = 37.9 bits (84), Expect = 0.033
Identities = 14/30 (46%), Positives = 20/30 (66%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE +T DV+S+GI++WEV+S
Sbjct: 790 WTAPEAIAYRKFTSASDVWSYGIVMWEVMS 819
>AF037332-1|AAD02031.1| 973|Homo sapiens Eph-like receptor tyrosine
kinase hEphB1b protein.
Length = 973
Score = 54.4 bits (125), Expect = 4e-07
Identities = 32/92 (34%), Positives = 50/92 (54%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVW-----RNRFVAVKHIN---SEAEKREFAIEV 167
F +EID S ++ V+G G FG V+KG R +VA+K + SE ++R+F E
Sbjct: 599 FAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEA 658
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPNI+RL G T+ V ++ E +
Sbjct: 659 SIMGQFDHPNIIRLEGVVTKSRPVMIITEFME 690
Score = 35.5 bits (78), Expect = 0.17
Identities = 14/30 (46%), Positives = 19/30 (63%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE +T DV+S+GI +WEV+S
Sbjct: 779 WTAPEAIAYRKFTSASDVWSYGIRMWEVMS 808
>AF037331-1|AAD02030.1| 984|Homo sapiens Eph-like receptor tyrosine
kinase hEphB1 protein.
Length = 984
Score = 54.4 bits (125), Expect = 4e-07
Identities = 32/92 (34%), Positives = 50/92 (54%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVW-----RNRFVAVKHIN---SEAEKREFAIEV 167
F +EID S ++ V+G G FG V+KG R +VA+K + SE ++R+F E
Sbjct: 610 FAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEA 669
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPNI+RL G T+ V ++ E +
Sbjct: 670 SIMGQFDHPNIIRLEGVVTKSRPVMIITEFME 701
Score = 33.9 bits (74), Expect = 0.53
Identities = 13/29 (44%), Positives = 18/29 (62%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVL 603
W APE +T DV+S+GI +WEV+
Sbjct: 790 WTAPEAIAYRKFTSASDVWSYGIHMWEVM 818
>U07358-1|AAA67343.1| 859|Homo sapiens serine/threonine protein
kinase protein.
Length = 859
Score = 54.0 bits (124), Expect = 5e-07
Identities = 29/84 (34%), Positives = 45/84 (53%)
Frame = +3
Query: 3 QQTFVEEIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEKREFAIEVRQLSR 182
QQ + E+ + EI +L VG GA G V+ G + VAVK + E +++ L +
Sbjct: 113 QQEDLWEVPFEEILDLQWVGSGAQGAVFLGRFHGEEVAVKKVRDLKET-----DIKHLRK 167
Query: 183 VCHPNIVRLYGACTRGAHVCLVME 254
+ HPNI+ G CT+ C++ME
Sbjct: 168 LKHPNIITFKGVCTQAPCYCILME 191
Score = 47.6 bits (108), Expect = 4e-05
Identities = 34/81 (41%), Positives = 46/81 (56%), Gaps = 4/81 (4%)
Frame = +2
Query: 266 GSLYNVLH-NRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQ 442
G LY VL RP T + + W+ A G+ YLH K +IHRDLK PN+L+
Sbjct: 196 GQLYEVLRAGRP---VTPSLLVDWSMGIAGGMNYLHLHK---IIHRDLKSPNMLIT-YDD 248
Query: 443 RLKICDFGTA---ADKATYMT 496
+KI DFGT+ +DK+T M+
Sbjct: 249 VVKISDFGTSKELSDKSTKMS 269
Score = 46.8 bits (106), Expect = 7e-05
Identities = 17/36 (47%), Positives = 26/36 (72%)
Frame = +1
Query: 514 AWMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRKPF 621
AWMAPEV +EK D++S+G++LWE+L+ P+
Sbjct: 275 AWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPY 310
>BC050050-1|AAH50050.1| 567|Homo sapiens MAP3K12 protein protein.
Length = 567
Score = 54.0 bits (124), Expect = 5e-07
Identities = 29/84 (34%), Positives = 45/84 (53%)
Frame = +3
Query: 3 QQTFVEEIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEKREFAIEVRQLSR 182
QQ + E+ + EI +L VG GA G V+ G + VAVK + E +++ L +
Sbjct: 146 QQEDLWEVPFEEILDLQWVGSGAQGAVFLGRFHGEEVAVKKVRDLKET-----DIKHLRK 200
Query: 183 VCHPNIVRLYGACTRGAHVCLVME 254
+ HPNI+ G CT+ C++ME
Sbjct: 201 LKHPNIITFKGVCTQAPCYCILME 224
Score = 47.6 bits (108), Expect = 4e-05
Identities = 34/81 (41%), Positives = 46/81 (56%), Gaps = 4/81 (4%)
Frame = +2
Query: 266 GSLYNVLH-NRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQ 442
G LY VL RP T + + W+ A G+ YLH K +IHRDLK PN+L+
Sbjct: 229 GQLYEVLRAGRP---VTPSLLVDWSMGIAGGMNYLHLHK---IIHRDLKSPNMLIT-YDD 281
Query: 443 RLKICDFGTA---ADKATYMT 496
+KI DFGT+ +DK+T M+
Sbjct: 282 VVKISDFGTSKELSDKSTKMS 302
Score = 46.8 bits (106), Expect = 7e-05
Identities = 17/36 (47%), Positives = 26/36 (72%)
Frame = +1
Query: 514 AWMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRKPF 621
AWMAPEV +EK D++S+G++LWE+L+ P+
Sbjct: 308 AWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPY 343
>AF283475-1|AAL67158.1| 859|Homo sapiens zipper protein kinase
protein.
Length = 859
Score = 54.0 bits (124), Expect = 5e-07
Identities = 29/84 (34%), Positives = 45/84 (53%)
Frame = +3
Query: 3 QQTFVEEIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEKREFAIEVRQLSR 182
QQ + E+ + EI +L VG GA G V+ G + VAVK + E +++ L +
Sbjct: 113 QQEDLWEVPFEEILDLQWVGSGAQGAVFLGRFHGEEVAVKKVRDLKET-----DIKHLRK 167
Query: 183 VCHPNIVRLYGACTRGAHVCLVME 254
+ HPNI+ G CT+ C++ME
Sbjct: 168 LKHPNIITFKGVCTQAPCYCILME 191
Score = 47.6 bits (108), Expect = 4e-05
Identities = 34/81 (41%), Positives = 46/81 (56%), Gaps = 4/81 (4%)
Frame = +2
Query: 266 GSLYNVLH-NRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQ 442
G LY VL RP T + + W+ A G+ YLH K +IHRDLK PN+L+
Sbjct: 196 GQLYEVLRAGRP---VTPSLLVDWSMGIAGGMNYLHLHK---IIHRDLKSPNMLIT-YDD 248
Query: 443 RLKICDFGTA---ADKATYMT 496
+KI DFGT+ +DK+T M+
Sbjct: 249 VVKISDFGTSKELSDKSTKMS 269
Score = 46.8 bits (106), Expect = 7e-05
Identities = 17/36 (47%), Positives = 26/36 (72%)
Frame = +1
Query: 514 AWMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRKPF 621
AWMAPEV +EK D++S+G++LWE+L+ P+
Sbjct: 275 AWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPY 310
>X58957-1|CAA41728.1| 659|Homo sapiens agammaglobulinaemia tyrosine
kinase protein.
Length = 659
Score = 53.6 bits (123), Expect = 6e-07
Identities = 28/80 (35%), Positives = 45/80 (56%), Gaps = 2/80 (2%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRF-VAVKHINSEA-EKREFAIEVRQLSRVCHP 194
EID ++ L +G G FGVV G WR ++ VA+K I + + EF E + + + H
Sbjct: 396 EIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHE 455
Query: 195 NIVRLYGACTRGAHVCLVME 254
+V+LYG CT+ + ++ E
Sbjct: 456 KLVQLYGVCTKQRPIFIITE 475
Score = 35.9 bits (79), Expect = 0.13
Identities = 12/33 (36%), Positives = 22/33 (66%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRK 615
W PEV S ++ K D++++G+++WE+ S K
Sbjct: 563 WSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGK 595
>U78027-4|AAB64205.1| 659|Homo sapiens Bruton's tyrosine kinase
protein.
Length = 659
Score = 53.6 bits (123), Expect = 6e-07
Identities = 28/80 (35%), Positives = 45/80 (56%), Gaps = 2/80 (2%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRF-VAVKHINSEA-EKREFAIEVRQLSRVCHP 194
EID ++ L +G G FGVV G WR ++ VA+K I + + EF E + + + H
Sbjct: 396 EIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHE 455
Query: 195 NIVRLYGACTRGAHVCLVME 254
+V+LYG CT+ + ++ E
Sbjct: 456 KLVQLYGVCTKQRPIFIITE 475
Score = 35.9 bits (79), Expect = 0.13
Identities = 12/33 (36%), Positives = 22/33 (66%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRK 615
W PEV S ++ K D++++G+++WE+ S K
Sbjct: 563 WSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGK 595
>U13433-1|AAC51347.1| 657|Homo sapiens Bruton's agammaglobulinemia
tyrosine kinase protein.
Length = 657
Score = 53.6 bits (123), Expect = 6e-07
Identities = 28/80 (35%), Positives = 45/80 (56%), Gaps = 2/80 (2%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRF-VAVKHINSEA-EKREFAIEVRQLSRVCHP 194
EID ++ L +G G FGVV G WR ++ VA+K I + + EF E + + + H
Sbjct: 394 EIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHE 453
Query: 195 NIVRLYGACTRGAHVCLVME 254
+V+LYG CT+ + ++ E
Sbjct: 454 KLVQLYGVCTKQRPIFIITE 473
Score = 35.9 bits (79), Expect = 0.13
Identities = 12/33 (36%), Positives = 22/33 (66%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRK 615
W PEV S ++ K D++++G+++WE+ S K
Sbjct: 561 WSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGK 593
>U10087-1|AAB60639.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 53.6 bits (123), Expect = 6e-07
Identities = 28/80 (35%), Positives = 45/80 (56%), Gaps = 2/80 (2%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRF-VAVKHINSEA-EKREFAIEVRQLSRVCHP 194
EID ++ L +G G FGVV G WR ++ VA+K I + + EF E + + + H
Sbjct: 396 EIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHE 455
Query: 195 NIVRLYGACTRGAHVCLVME 254
+V+LYG CT+ + ++ E
Sbjct: 456 KLVQLYGVCTKQRPIFIITE 475
Score = 35.9 bits (79), Expect = 0.13
Identities = 12/33 (36%), Positives = 22/33 (66%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRK 615
W PEV S ++ K D++++G+++WE+ S K
Sbjct: 563 WSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGK 595
>L31572-1|AAA61479.1| 659|Homo sapiens Bruton agammaglobulinemia
protein.
Length = 659
Score = 53.6 bits (123), Expect = 6e-07
Identities = 28/80 (35%), Positives = 45/80 (56%), Gaps = 2/80 (2%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRF-VAVKHINSEA-EKREFAIEVRQLSRVCHP 194
EID ++ L +G G FGVV G WR ++ VA+K I + + EF E + + + H
Sbjct: 396 EIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHE 455
Query: 195 NIVRLYGACTRGAHVCLVME 254
+V+LYG CT+ + ++ E
Sbjct: 456 KLVQLYGVCTKQRPIFIITE 475
Score = 35.9 bits (79), Expect = 0.13
Identities = 12/33 (36%), Positives = 22/33 (66%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRK 615
W PEV S ++ K D++++G+++WE+ S K
Sbjct: 563 WSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGK 595
>BC109080-1|AAI09081.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 53.6 bits (123), Expect = 6e-07
Identities = 28/80 (35%), Positives = 45/80 (56%), Gaps = 2/80 (2%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRF-VAVKHINSEA-EKREFAIEVRQLSRVCHP 194
EID ++ L +G G FGVV G WR ++ VA+K I + + EF E + + + H
Sbjct: 396 EIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHE 455
Query: 195 NIVRLYGACTRGAHVCLVME 254
+V+LYG CT+ + ++ E
Sbjct: 456 KLVQLYGVCTKQRPIFIITE 475
Score = 35.9 bits (79), Expect = 0.13
Identities = 12/33 (36%), Positives = 22/33 (66%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRK 615
W PEV S ++ K D++++G+++WE+ S K
Sbjct: 563 WSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGK 595
>BC109079-1|AAI09080.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 53.6 bits (123), Expect = 6e-07
Identities = 28/80 (35%), Positives = 45/80 (56%), Gaps = 2/80 (2%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRF-VAVKHINSEA-EKREFAIEVRQLSRVCHP 194
EID ++ L +G G FGVV G WR ++ VA+K I + + EF E + + + H
Sbjct: 396 EIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHE 455
Query: 195 NIVRLYGACTRGAHVCLVME 254
+V+LYG CT+ + ++ E
Sbjct: 456 KLVQLYGVCTKQRPIFIITE 475
Score = 35.9 bits (79), Expect = 0.13
Identities = 12/33 (36%), Positives = 22/33 (66%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRK 615
W PEV S ++ K D++++G+++WE+ S K
Sbjct: 563 WSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGK 595
>AM051278-1|CAJ19684.1| 197|Homo sapiens dominant-negative
kinase-deficient Brutons tyrosine kinase isoform 4
protein.
Length = 197
Score = 53.6 bits (123), Expect = 6e-07
Identities = 28/80 (35%), Positives = 45/80 (56%), Gaps = 2/80 (2%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRF-VAVKHINSEA-EKREFAIEVRQLSRVCHP 194
EID ++ L +G G FGVV G WR ++ VA+K I + + EF E + + + H
Sbjct: 67 EIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHE 126
Query: 195 NIVRLYGACTRGAHVCLVME 254
+V+LYG CT+ + ++ E
Sbjct: 127 KLVQLYGVCTKQRPIFIITE 146
>AM051277-1|CAJ19683.1| 172|Homo sapiens dominant-negative
kinase-deficient Brutons tyrosine kinase isoform 3
protein.
Length = 172
Score = 53.6 bits (123), Expect = 6e-07
Identities = 28/80 (35%), Positives = 45/80 (56%), Gaps = 2/80 (2%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRF-VAVKHINSEA-EKREFAIEVRQLSRVCHP 194
EID ++ L +G G FGVV G WR ++ VA+K I + + EF E + + + H
Sbjct: 67 EIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHE 126
Query: 195 NIVRLYGACTRGAHVCLVME 254
+V+LYG CT+ + ++ E
Sbjct: 127 KLVQLYGVCTKQRPIFIITE 146
>AM051276-1|CAJ19682.1| 319|Homo sapiens dominant-negative
kinase-deficient Brutons tyrosine kinase isoform 2
protein.
Length = 319
Score = 53.6 bits (123), Expect = 6e-07
Identities = 28/80 (35%), Positives = 45/80 (56%), Gaps = 2/80 (2%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRF-VAVKHINSEA-EKREFAIEVRQLSRVCHP 194
EID ++ L +G G FGVV G WR ++ VA+K I + + EF E + + + H
Sbjct: 67 EIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHE 126
Query: 195 NIVRLYGACTRGAHVCLVME 254
+V+LYG CT+ + ++ E
Sbjct: 127 KLVQLYGVCTKQRPIFIITE 146
Score = 35.9 bits (79), Expect = 0.13
Identities = 12/33 (36%), Positives = 22/33 (66%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRK 615
W PEV S ++ K D++++G+++WE+ S K
Sbjct: 234 WSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGK 266
>AL035422-3|CAB55876.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 53.6 bits (123), Expect = 6e-07
Identities = 28/80 (35%), Positives = 45/80 (56%), Gaps = 2/80 (2%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRF-VAVKHINSEA-EKREFAIEVRQLSRVCHP 194
EID ++ L +G G FGVV G WR ++ VA+K I + + EF E + + + H
Sbjct: 396 EIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHE 455
Query: 195 NIVRLYGACTRGAHVCLVME 254
+V+LYG CT+ + ++ E
Sbjct: 456 KLVQLYGVCTKQRPIFIITE 475
Score = 35.9 bits (79), Expect = 0.13
Identities = 12/33 (36%), Positives = 22/33 (66%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRK 615
W PEV S ++ K D++++G+++WE+ S K
Sbjct: 563 WSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGK 595
>X83107-1|CAA58169.1| 675|Homo sapiens bmx protein.
Length = 675
Score = 53.2 bits (122), Expect = 8e-07
Identities = 28/80 (35%), Positives = 45/80 (56%), Gaps = 2/80 (2%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRF-VAVKHINSEA-EKREFAIEVRQLSRVCHP 194
E+ EI L +G G FGVV G W+ ++ VAVK I + + EF E + + ++ HP
Sbjct: 411 ELKREEITLLKELGSGQFGVVQLGKWKGQYDVAVKMIKEGSMSEDEFFQEAQTMMKLSHP 470
Query: 195 NIVRLYGACTRGAHVCLVME 254
+V+ YG C++ + +V E
Sbjct: 471 KLVKFYGVCSKEYPIYIVTE 490
Score = 41.9 bits (94), Expect = 0.002
Identities = 17/33 (51%), Positives = 23/33 (69%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRK 615
W APEVF Y+ K DV+++GI++WEV S K
Sbjct: 578 WSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGK 610
>BC016652-1|AAH16652.1| 675|Homo sapiens BMX non-receptor tyrosine
kinase protein.
Length = 675
Score = 53.2 bits (122), Expect = 8e-07
Identities = 28/80 (35%), Positives = 45/80 (56%), Gaps = 2/80 (2%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRF-VAVKHINSEA-EKREFAIEVRQLSRVCHP 194
E+ EI L +G G FGVV G W+ ++ VAVK I + + EF E + + ++ HP
Sbjct: 411 ELKREEITLLKELGSGQFGVVQLGKWKGQYDVAVKMIKEGSMSEDEFFQEAQTMMKLSHP 470
Query: 195 NIVRLYGACTRGAHVCLVME 254
+V+ YG C++ + +V E
Sbjct: 471 KLVKFYGVCSKEYPIYIVTE 490
Score = 41.9 bits (94), Expect = 0.002
Identities = 17/33 (51%), Positives = 23/33 (69%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRK 615
W APEVF Y+ K DV+++GI++WEV S K
Sbjct: 578 WSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGK 610
>AF045459-1|AAC08966.1| 697|Homo sapiens Etk/Bmx cytosolic tyrosine
kinase protein.
Length = 697
Score = 53.2 bits (122), Expect = 8e-07
Identities = 28/80 (35%), Positives = 45/80 (56%), Gaps = 2/80 (2%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRF-VAVKHINSEA-EKREFAIEVRQLSRVCHP 194
E+ EI L +G G FGVV G W+ ++ VAVK I + + EF E + + ++ HP
Sbjct: 433 ELKREEITLLKELGSGQFGVVQLGKWKGQYDVAVKMIKEGSMSEDEFFQEAQTMMKLSHP 492
Query: 195 NIVRLYGACTRGAHVCLVME 254
+V+ YG C++ + +V E
Sbjct: 493 KLVKFYGVCSKEYPIYIVTE 512
Score = 41.9 bits (94), Expect = 0.002
Identities = 17/33 (51%), Positives = 23/33 (69%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRK 615
W APEVF Y+ K DV+++GI++WEV S K
Sbjct: 600 WSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGK 632
>BC133706-1|AAI33707.1| 1104|Homo sapiens MAP3K9 protein protein.
Length = 1104
Score = 52.8 bits (121), Expect = 1e-06
Identities = 31/87 (35%), Positives = 49/87 (56%), Gaps = 6/87 (6%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEKR-EFAIE-VRQLSRVC-- 188
EID++E+ ++G G FG V++ W VAVK + ++ IE VRQ +++
Sbjct: 138 EIDFAELTLEEIIGIGGFGKVYRAFWIGDEVAVKAARHDPDEDISQTIENVRQEAKLFAM 197
Query: 189 --HPNIVRLYGACTRGAHVCLVMEMQK 263
HPNI+ L G C + ++CLVME +
Sbjct: 198 LKHPNIIALRGVCLKEPNLCLVMEFAR 224
Score = 47.6 bits (108), Expect = 4e-05
Identities = 18/36 (50%), Positives = 27/36 (75%)
Frame = +1
Query: 514 AWMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRKPF 621
AWMAPEV S +++ DV+S+G++LWE+L+ PF
Sbjct: 314 AWMAPEVIRASMFSKGSDVWSYGVLLWELLTGEVPF 349
Score = 46.8 bits (106), Expect = 7e-05
Identities = 31/81 (38%), Positives = 41/81 (50%), Gaps = 7/81 (8%)
Frame = +2
Query: 257 AEGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVG- 433
A GG L VL + P ++WA Q A G+ YLH P+IHRDLK N+L++
Sbjct: 223 ARGGPLNRVLSGKRIPPDIL---VNWAVQIARGMNYLHDEAIVPIIHRDLKSSNILILQK 279
Query: 434 ------GGQRLKICDFGTAAD 478
+ LKI DFG A +
Sbjct: 280 VENGDLSNKILKITDFGLARE 300
>BC111407-1|AAI11408.1| 1103|Homo sapiens MAP3K9 protein protein.
Length = 1103
Score = 52.8 bits (121), Expect = 1e-06
Identities = 31/87 (35%), Positives = 49/87 (56%), Gaps = 6/87 (6%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEKR-EFAIE-VRQLSRVC-- 188
EID++E+ ++G G FG V++ W VAVK + ++ IE VRQ +++
Sbjct: 137 EIDFAELTLEEIIGIGGFGKVYRAFWIGDEVAVKAARHDPDEDISQTIENVRQEAKLFAM 196
Query: 189 --HPNIVRLYGACTRGAHVCLVMEMQK 263
HPNI+ L G C + ++CLVME +
Sbjct: 197 LKHPNIIALRGVCLKEPNLCLVMEFAR 223
Score = 47.6 bits (108), Expect = 4e-05
Identities = 18/36 (50%), Positives = 27/36 (75%)
Frame = +1
Query: 514 AWMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRKPF 621
AWMAPEV S +++ DV+S+G++LWE+L+ PF
Sbjct: 313 AWMAPEVIRASMFSKGSDVWSYGVLLWELLTGEVPF 348
Score = 46.8 bits (106), Expect = 7e-05
Identities = 31/81 (38%), Positives = 41/81 (50%), Gaps = 7/81 (8%)
Frame = +2
Query: 257 AEGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVG- 433
A GG L VL + P ++WA Q A G+ YLH P+IHRDLK N+L++
Sbjct: 222 ARGGPLNRVLSGKRIPPDIL---VNWAVQIARGMNYLHDEAIVPIIHRDLKSSNILILQK 278
Query: 434 ------GGQRLKICDFGTAAD 478
+ LKI DFG A +
Sbjct: 279 VENGDLSNKILKITDFGLARE 299
>AY327900-1|AAQ23054.1| 1104|Homo sapiens mixed-lineage protein
kinase 1 protein.
Length = 1104
Score = 52.8 bits (121), Expect = 1e-06
Identities = 31/87 (35%), Positives = 49/87 (56%), Gaps = 6/87 (6%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEKR-EFAIE-VRQLSRVC-- 188
EID++E+ ++G G FG V++ W VAVK + ++ IE VRQ +++
Sbjct: 138 EIDFAELTLEEIIGIGGFGKVYRAFWIGDEVAVKAARHDPDEDISQTIENVRQEAKLFAM 197
Query: 189 --HPNIVRLYGACTRGAHVCLVMEMQK 263
HPNI+ L G C + ++CLVME +
Sbjct: 198 LKHPNIIALRGVCLKEPNLCLVMEFAR 224
Score = 47.6 bits (108), Expect = 4e-05
Identities = 18/36 (50%), Positives = 27/36 (75%)
Frame = +1
Query: 514 AWMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRKPF 621
AWMAPEV S +++ DV+S+G++LWE+L+ PF
Sbjct: 314 AWMAPEVIRASMFSKGSDVWSYGVLLWELLTGEVPF 349
Score = 46.8 bits (106), Expect = 7e-05
Identities = 31/81 (38%), Positives = 41/81 (50%), Gaps = 7/81 (8%)
Frame = +2
Query: 257 AEGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVG- 433
A GG L VL + P ++WA Q A G+ YLH P+IHRDLK N+L++
Sbjct: 223 ARGGPLNRVLSGKRIPPDIL---VNWAVQIARGMNYLHDEAIVPIIHRDLKSSNILILQK 279
Query: 434 ------GGQRLKICDFGTAAD 478
+ LKI DFG A +
Sbjct: 280 VENGDLSNKILKITDFGLARE 300
>AF251442-1|AAG44591.1| 1066|Homo sapiens mixed lineage kinase MLK1
protein.
Length = 1066
Score = 52.8 bits (121), Expect = 1e-06
Identities = 31/87 (35%), Positives = 49/87 (56%), Gaps = 6/87 (6%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEKR-EFAIE-VRQLSRVC-- 188
EID++E+ ++G G FG V++ W VAVK + ++ IE VRQ +++
Sbjct: 86 EIDFAELTLEEIIGIGGFGKVYRAFWIGDEVAVKAARHDPDEDISQTIENVRQEAKLFAM 145
Query: 189 --HPNIVRLYGACTRGAHVCLVMEMQK 263
HPNI+ L G C + ++CLVME +
Sbjct: 146 LKHPNIIALRGVCLKEPNLCLVMEFAR 172
Score = 47.6 bits (108), Expect = 4e-05
Identities = 18/36 (50%), Positives = 27/36 (75%)
Frame = +1
Query: 514 AWMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRKPF 621
AWMAPEV S +++ DV+S+G++LWE+L+ PF
Sbjct: 262 AWMAPEVIRASMFSKGSDVWSYGVLLWELLTGEVPF 297
Score = 46.8 bits (106), Expect = 7e-05
Identities = 31/81 (38%), Positives = 41/81 (50%), Gaps = 7/81 (8%)
Frame = +2
Query: 257 AEGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVG- 433
A GG L VL + P ++WA Q A G+ YLH P+IHRDLK N+L++
Sbjct: 171 ARGGPLNRVLSGKRIPPDIL---VNWAVQIARGMNYLHDEAIVPIIHRDLKSSNILILQK 227
Query: 434 ------GGQRLKICDFGTAAD 478
+ LKI DFG A +
Sbjct: 228 VENGDLSNKILKITDFGLARE 248
>AF042838-1|AAC97073.1| 1495|Homo sapiens MEK kinase 1 protein.
Length = 1495
Score = 52.4 bits (120), Expect = 1e-06
Identities = 40/114 (35%), Positives = 59/114 (51%), Gaps = 6/114 (5%)
Frame = +2
Query: 197 HCAIVRSVHAGCSRMPRHGDAE---GGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYL 367
H I+R + A C + + E GGS+ ++L K + +++ Q G++YL
Sbjct: 1286 HPNIIRMLGATCEKSNYNLFIEWMAGGSVAHLLSKYGAFKESVV--INYTEQLLRGLSYL 1343
Query: 368 HSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTA---ADKATYMTNNKGVLLG 520
H + +IHRD+K NLL+ GQRL+I DFG A A K T +G LLG
Sbjct: 1344 HENQ---IIHRDVKGANLLIDSTGQRLRIADFGAAARLASKGTGAGEFQGQLLG 1394
Score = 34.7 bits (76), Expect = 0.31
Identities = 15/36 (41%), Positives = 21/36 (58%)
Frame = +1
Query: 514 AWMAPEVFEGSTYTEKCDVFSWGIILWEVLSRRKPF 621
A+MAPEV G Y CDV+S G + E+ + P+
Sbjct: 1397 AFMAPEVLRGQQYGRSCDVWSVGCAIIEMACAKPPW 1432
Score = 33.9 bits (74), Expect = 0.53
Identities = 26/94 (27%), Positives = 49/94 (52%), Gaps = 10/94 (10%)
Frame = +3
Query: 3 QQTFVEEIDYSEIQELSVVGKGAFGVVWKG--VWRNRFVAVKHI----NSEAEKREFAI- 161
+Q + E+ ++ + Q+ +G GAF ++ V +AVK + N+ +E+ E
Sbjct: 1217 KQPYREDTEWLKGQQ---IGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEA 1273
Query: 162 ---EVRQLSRVCHPNIVRLYGACTRGAHVCLVME 254
E+R +S + HPNI+R+ GA ++ L +E
Sbjct: 1274 LREEIRMMSHLNHPNIIRMLGATCEKSNYNLFIE 1307
>BX538196-1|CAD98063.1| 109|Homo sapiens hypothetical protein
protein.
Length = 109
Score = 52.0 bits (119), Expect = 2e-06
Identities = 27/68 (39%), Positives = 37/68 (54%), Gaps = 2/68 (2%)
Frame = +3
Query: 66 GAFGVVWKGVWRNRF-VAVKHINSEAEKRE-FAIEVRQLSRVCHPNIVRLYGACTRGAHV 239
G FG+V G W N+ VA+K I A E F E + ++ HP +V+LYG C A +
Sbjct: 1 GQFGLVHLGYWLNKDKVAIKTIREGAMSEEDFIEEAEVMMKLSHPKLVQLYGVCLEQAPI 60
Query: 240 CLVMEMQK 263
CLV E +
Sbjct: 61 CLVFEFME 68
>X75208-1|CAA53021.1| 998|Homo sapiens protein tyrosine
kinase-receptor protein.
Length = 998
Score = 51.2 bits (117), Expect = 3e-06
Identities = 34/96 (35%), Positives = 52/96 (54%), Gaps = 9/96 (9%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVW-----RNRFVAVKHIN---SEAEKREFAIEV 167
F +EID S ++ V+G G FG V +G R FVA+K + +E ++R+F E
Sbjct: 624 FAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEA 683
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVME-MQKVAL 272
+ + HPNI+RL G T+ V ++ E M+ AL
Sbjct: 684 SIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCAL 719
Score = 37.9 bits (84), Expect = 0.033
Identities = 14/30 (46%), Positives = 20/30 (66%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE +T DV+S+GI++WEV+S
Sbjct: 804 WTAPEAIAYRKFTSASDVWSYGIVMWEVMS 833
>BC111965-1|AAI11966.1| 863|Homo sapiens AP2 associated kinase 1
protein.
Length = 863
Score = 51.2 bits (117), Expect = 3e-06
Identities = 28/73 (38%), Positives = 41/73 (56%)
Frame = +2
Query: 263 GGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQ 442
GG + N+++ R + +T + E VA LH K P+IHRDLK N+LL G
Sbjct: 131 GGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKT-PIIHRDLKVENILLHDRGH 189
Query: 443 RLKICDFGTAADK 481
+ +CDFG+A +K
Sbjct: 190 YV-LCDFGSATNK 201
>BC104842-1|AAI04843.1| 863|Homo sapiens AP2 associated kinase 1
protein.
Length = 863
Score = 51.2 bits (117), Expect = 3e-06
Identities = 28/73 (38%), Positives = 41/73 (56%)
Frame = +2
Query: 263 GGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQ 442
GG + N+++ R + +T + E VA LH K P+IHRDLK N+LL G
Sbjct: 131 GGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKT-PIIHRDLKVENILLHDRGH 189
Query: 443 RLKICDFGTAADK 481
+ +CDFG+A +K
Sbjct: 190 YV-LCDFGSATNK 201
>BC052968-1|AAH52968.1| 998|Homo sapiens EPH receptor B3 protein.
Length = 998
Score = 51.2 bits (117), Expect = 3e-06
Identities = 34/96 (35%), Positives = 52/96 (54%), Gaps = 9/96 (9%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVW-----RNRFVAVKHIN---SEAEKREFAIEV 167
F +EID S ++ V+G G FG V +G R FVA+K + +E ++R+F E
Sbjct: 624 FAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEA 683
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVME-MQKVAL 272
+ + HPNI+RL G T+ V ++ E M+ AL
Sbjct: 684 SIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCAL 719
Score = 37.9 bits (84), Expect = 0.033
Identities = 14/30 (46%), Positives = 20/30 (66%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE +T DV+S+GI++WEV+S
Sbjct: 804 WTAPEAIAYRKFTSASDVWSYGIVMWEVMS 833
>BC002695-1|AAH02695.1| 474|Homo sapiens AAK1 protein protein.
Length = 474
Score = 51.2 bits (117), Expect = 3e-06
Identities = 28/73 (38%), Positives = 41/73 (56%)
Frame = +2
Query: 263 GGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQ 442
GG + N+++ R + +T + E VA LH K P+IHRDLK N+LL G
Sbjct: 131 GGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKT-PIIHRDLKVENILLHDRGH 189
Query: 443 RLKICDFGTAADK 481
+ +CDFG+A +K
Sbjct: 190 YV-LCDFGSATNK 201
>AC079121-1|AAY14931.1| 769|Homo sapiens unknown protein.
Length = 769
Score = 51.2 bits (117), Expect = 3e-06
Identities = 28/73 (38%), Positives = 41/73 (56%)
Frame = +2
Query: 263 GGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQ 442
GG + N+++ R + +T + E VA LH K P+IHRDLK N+LL G
Sbjct: 37 GGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKT-PIIHRDLKVENILLHDRGH 95
Query: 443 RLKICDFGTAADK 481
+ +CDFG+A +K
Sbjct: 96 YV-LCDFGSATNK 107
>AB028971-1|BAA83000.2| 897|Homo sapiens KIAA1048 protein protein.
Length = 897
Score = 51.2 bits (117), Expect = 3e-06
Identities = 28/73 (38%), Positives = 41/73 (56%)
Frame = +2
Query: 263 GGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQ 442
GG + N+++ R + +T + E VA LH K P+IHRDLK N+LL G
Sbjct: 165 GGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKT-PIIHRDLKVENILLHDRGH 223
Query: 443 RLKICDFGTAADK 481
+ +CDFG+A +K
Sbjct: 224 YV-LCDFGSATNK 235
>X03484-1|CAA27204.1| 648|Homo sapiens protein ( Human mRNA for raf
oncogene. ).
Length = 648
Score = 50.8 bits (116), Expect = 4e-06
Identities = 32/77 (41%), Positives = 45/77 (58%)
Frame = +2
Query: 260 EGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGG 439
EG SLY LH + + K+ + ARQ A+G+ YLH+ K +IHRD+K N+ L G
Sbjct: 425 EGSSLYKHLHVQ-ETKFQMFQLIDIARQTAQGMDYLHA---KNIIHRDMKSNNIFL-HEG 479
Query: 440 QRLKICDFGTAADKATY 490
+KI DFG A K+ +
Sbjct: 480 LTVKIGDFGLATVKSRW 496
Score = 38.7 bits (86), Expect = 0.019
Identities = 25/73 (34%), Positives = 38/73 (52%), Gaps = 4/73 (5%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHIN----SEAEKREFAIEVRQLSRVC 188
EI+ SE+ + +G G+FG V+KG W VAVK + + + + F EV L +
Sbjct: 343 EIEASEVMLSTRIGSGSFGTVYKGKWHGD-VAVKILKVVDPTPEQFQAFRNEVAVLRKTR 401
Query: 189 HPNIVRLYGACTR 227
H NI+ G T+
Sbjct: 402 HVNILLFMGYMTK 414
Score = 35.1 bits (77), Expect = 0.23
Identities = 14/38 (36%), Positives = 27/38 (71%), Gaps = 3/38 (7%)
Frame = +1
Query: 517 WMAPEVF---EGSTYTEKCDVFSWGIILWEVLSRRKPF 621
WMAPEV + + ++ + DV+S+GI+L+E+++ P+
Sbjct: 511 WMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPY 548
>L00212-1|AAA60247.1| 421|Homo sapiens RAF1 protein.
Length = 421
Score = 50.8 bits (116), Expect = 4e-06
Identities = 32/77 (41%), Positives = 45/77 (58%)
Frame = +2
Query: 260 EGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGG 439
EG SLY LH + + K+ + ARQ A+G+ YLH+ K +IHRD+K N+ L G
Sbjct: 198 EGSSLYKHLHVQ-ETKFQMFQLIDIARQTAQGMDYLHA---KNIIHRDMKSNNIFL-HEG 252
Query: 440 QRLKICDFGTAADKATY 490
+KI DFG A K+ +
Sbjct: 253 LTVKIGDFGLATVKSRW 269
Score = 38.7 bits (86), Expect = 0.019
Identities = 25/73 (34%), Positives = 38/73 (52%), Gaps = 4/73 (5%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHIN----SEAEKREFAIEVRQLSRVC 188
EI+ SE+ + +G G+FG V+KG W VAVK + + + + F EV L +
Sbjct: 116 EIEASEVMLSTRIGSGSFGTVYKGKWHGD-VAVKILKVVDPTPEQFQAFRNEVAVLRKTR 174
Query: 189 HPNIVRLYGACTR 227
H NI+ G T+
Sbjct: 175 HVNILLFMGYMTK 187
Score = 35.1 bits (77), Expect = 0.23
Identities = 14/38 (36%), Positives = 27/38 (71%), Gaps = 3/38 (7%)
Frame = +1
Query: 517 WMAPEVF---EGSTYTEKCDVFSWGIILWEVLSRRKPF 621
WMAPEV + + ++ + DV+S+GI+L+E+++ P+
Sbjct: 284 WMAPEVIRMQDNNPFSFQSDVYSYGIVLYELITGELPY 321
>BC018119-1|AAH18119.1| 648|Homo sapiens v-raf-1 murine leukemia
viral oncogene homolog 1 protein.
Length = 648
Score = 50.8 bits (116), Expect = 4e-06
Identities = 32/77 (41%), Positives = 45/77 (58%)
Frame = +2
Query: 260 EGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGG 439
EG SLY LH + + K+ + ARQ A+G+ YLH+ K +IHRD+K N+ L G
Sbjct: 425 EGSSLYKHLHVQ-ETKFQMFQLIDIARQTAQGMDYLHA---KNIIHRDMKSNNIFL-HEG 479
Query: 440 QRLKICDFGTAADKATY 490
+KI DFG A K+ +
Sbjct: 480 LTVKIGDFGLATVKSRW 496
Score = 38.7 bits (86), Expect = 0.019
Identities = 25/73 (34%), Positives = 38/73 (52%), Gaps = 4/73 (5%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHIN----SEAEKREFAIEVRQLSRVC 188
EI+ SE+ + +G G+FG V+KG W VAVK + + + + F EV L +
Sbjct: 343 EIEASEVMLSTRIGSGSFGTVYKGKWHGD-VAVKILKVVDPTPEQFQAFRNEVAVLRKTR 401
Query: 189 HPNIVRLYGACTR 227
H NI+ G T+
Sbjct: 402 HVNILLFMGYMTK 414
Score = 35.1 bits (77), Expect = 0.23
Identities = 14/38 (36%), Positives = 27/38 (71%), Gaps = 3/38 (7%)
Frame = +1
Query: 517 WMAPEVF---EGSTYTEKCDVFSWGIILWEVLSRRKPF 621
WMAPEV + + ++ + DV+S+GI+L+E+++ P+
Sbjct: 511 WMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPY 548
>AY271661-1|AAP03432.1| 648|Homo sapiens v-raf-1 murine leukemia
viral oncogene homolog 1 protein.
Length = 648
Score = 50.8 bits (116), Expect = 4e-06
Identities = 32/77 (41%), Positives = 45/77 (58%)
Frame = +2
Query: 260 EGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGG 439
EG SLY LH + + K+ + ARQ A+G+ YLH+ K +IHRD+K N+ L G
Sbjct: 425 EGSSLYKHLHVQ-ETKFQMFQLIDIARQTAQGMDYLHA---KNIIHRDMKSNNIFL-HEG 479
Query: 440 QRLKICDFGTAADKATY 490
+KI DFG A K+ +
Sbjct: 480 LTVKIGDFGLATVKSRW 496
Score = 38.7 bits (86), Expect = 0.019
Identities = 25/73 (34%), Positives = 38/73 (52%), Gaps = 4/73 (5%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHIN----SEAEKREFAIEVRQLSRVC 188
EI+ SE+ + +G G+FG V+KG W VAVK + + + + F EV L +
Sbjct: 343 EIEASEVMLSTRIGSGSFGTVYKGKWHGD-VAVKILKVVDPTPEQFQAFRNEVAVLRKTR 401
Query: 189 HPNIVRLYGACTR 227
H NI+ G T+
Sbjct: 402 HVNILLFMGYMTK 414
Score = 35.1 bits (77), Expect = 0.23
Identities = 14/38 (36%), Positives = 27/38 (71%), Gaps = 3/38 (7%)
Frame = +1
Query: 517 WMAPEVF---EGSTYTEKCDVFSWGIILWEVLSRRKPF 621
WMAPEV + + ++ + DV+S+GI+L+E+++ P+
Sbjct: 511 WMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPY 548
>Z25428-1|CAA80915.1| 111|Homo sapiens protein-serine/threonine
kinase protein.
Length = 111
Score = 50.4 bits (115), Expect = 6e-06
Identities = 35/80 (43%), Positives = 45/80 (56%), Gaps = 3/80 (3%)
Frame = +2
Query: 266 GSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQR 445
G LY VL R K T + W+ A G+ YLH K +IHRDLK PN +LV
Sbjct: 10 GQLYEVL--RAGRKITPRLLVDWSTGIASGMNYLHLHK---IIHRDLKSPN-VLVTHTDA 63
Query: 446 LKICDFGTA---ADKATYMT 496
+KI DFGT+ +DK+T M+
Sbjct: 64 VKISDFGTSKELSDKSTKMS 83
>X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRNA
encoding p150 protein. ).
Length = 1130
Score = 50.4 bits (115), Expect = 6e-06
Identities = 27/81 (33%), Positives = 45/81 (55%), Gaps = 3/81 (3%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWR--NRFVAVKHINSEA-EKREFAIEVRQLSRVCH 191
E++ ++I +G G +G V++GVW+ + VAVK + + E EF E + + H
Sbjct: 236 EMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKH 295
Query: 192 PNIVRLYGACTRGAHVCLVME 254
PN+V+L G CTR ++ E
Sbjct: 296 PNLVQLLGVCTREPPFYIITE 316
Score = 33.1 bits (72), Expect = 0.93
Identities = 11/28 (39%), Positives = 20/28 (71%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEV 600
W APE + ++ K DV+++G++LWE+
Sbjct: 405 WTAPESLAYNKFSIKSDVWAFGVLLWEI 432
>U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene
tyrosine-protein kinase protein.
Length = 1130
Score = 50.4 bits (115), Expect = 6e-06
Identities = 27/81 (33%), Positives = 45/81 (55%), Gaps = 3/81 (3%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWR--NRFVAVKHINSEA-EKREFAIEVRQLSRVCH 191
E++ ++I +G G +G V++GVW+ + VAVK + + E EF E + + H
Sbjct: 236 EMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKH 295
Query: 192 PNIVRLYGACTRGAHVCLVME 254
PN+V+L G CTR ++ E
Sbjct: 296 PNLVQLLGVCTREPPFYIITE 316
Score = 33.1 bits (72), Expect = 0.93
Identities = 11/28 (39%), Positives = 20/28 (71%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEV 600
W APE + ++ K DV+++G++LWE+
Sbjct: 405 WTAPESLAYNKFSIKSDVWAFGVLLWEI 432
>U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene
tyrosine-protein kinase protein.
Length = 1149
Score = 50.4 bits (115), Expect = 6e-06
Identities = 27/81 (33%), Positives = 45/81 (55%), Gaps = 3/81 (3%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWR--NRFVAVKHINSEA-EKREFAIEVRQLSRVCH 191
E++ ++I +G G +G V++GVW+ + VAVK + + E EF E + + H
Sbjct: 255 EMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKH 314
Query: 192 PNIVRLYGACTRGAHVCLVME 254
PN+V+L G CTR ++ E
Sbjct: 315 PNLVQLLGVCTREPPFYIITE 335
Score = 33.1 bits (72), Expect = 0.93
Identities = 11/28 (39%), Positives = 20/28 (71%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEV 600
W APE + ++ K DV+++G++LWE+
Sbjct: 424 WTAPESLAYNKFSIKSDVWAFGVLLWEI 451
>M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein.
Length = 1130
Score = 50.4 bits (115), Expect = 6e-06
Identities = 27/81 (33%), Positives = 45/81 (55%), Gaps = 3/81 (3%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWR--NRFVAVKHINSEA-EKREFAIEVRQLSRVCH 191
E++ ++I +G G +G V++GVW+ + VAVK + + E EF E + + H
Sbjct: 236 EMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKH 295
Query: 192 PNIVRLYGACTRGAHVCLVME 254
PN+V+L G CTR ++ E
Sbjct: 296 PNLVQLLGVCTREPPFYIITE 316
Score = 33.1 bits (72), Expect = 0.93
Identities = 11/28 (39%), Positives = 20/28 (71%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEV 600
W APE + ++ K DV+++G++LWE+
Sbjct: 405 WTAPESLAYNKFSIKSDVWAFGVLLWEI 432
>DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 50.4 bits (115), Expect = 6e-06
Identities = 27/81 (33%), Positives = 45/81 (55%), Gaps = 3/81 (3%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWR--NRFVAVKHINSEA-EKREFAIEVRQLSRVCH 191
E++ ++I +G G +G V++GVW+ + VAVK + + E EF E + + H
Sbjct: 255 EMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKH 314
Query: 192 PNIVRLYGACTRGAHVCLVME 254
PN+V+L G CTR ++ E
Sbjct: 315 PNLVQLLGVCTREPPFYIITE 335
Score = 33.1 bits (72), Expect = 0.93
Identities = 11/28 (39%), Positives = 20/28 (71%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEV 600
W APE + ++ K DV+++G++LWE+
Sbjct: 424 WTAPESLAYNKFSIKSDVWAFGVLLWEI 451
>BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 50.4 bits (115), Expect = 6e-06
Identities = 27/81 (33%), Positives = 45/81 (55%), Gaps = 3/81 (3%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWR--NRFVAVKHINSEA-EKREFAIEVRQLSRVCH 191
E++ ++I +G G +G V++GVW+ + VAVK + + E EF E + + H
Sbjct: 255 EMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKH 314
Query: 192 PNIVRLYGACTRGAHVCLVME 254
PN+V+L G CTR ++ E
Sbjct: 315 PNLVQLLGVCTREPPFYIITE 335
Score = 33.1 bits (72), Expect = 0.93
Identities = 11/28 (39%), Positives = 20/28 (71%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEV 600
W APE + ++ K DV+++G++LWE+
Sbjct: 424 WTAPESLAYNKFSIKSDVWAFGVLLWEI 451
>AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 50.4 bits (115), Expect = 6e-06
Identities = 27/81 (33%), Positives = 45/81 (55%), Gaps = 3/81 (3%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWR--NRFVAVKHINSEA-EKREFAIEVRQLSRVCH 191
E++ ++I +G G +G V++GVW+ + VAVK + + E EF E + + H
Sbjct: 255 EMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKH 314
Query: 192 PNIVRLYGACTRGAHVCLVME 254
PN+V+L G CTR ++ E
Sbjct: 315 PNLVQLLGVCTREPPFYIITE 335
Score = 33.1 bits (72), Expect = 0.93
Identities = 11/28 (39%), Positives = 20/28 (71%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEV 600
W APE + ++ K DV+++G++LWE+
Sbjct: 424 WTAPESLAYNKFSIKSDVWAFGVLLWEI 451
>AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 50.4 bits (115), Expect = 6e-06
Identities = 27/81 (33%), Positives = 45/81 (55%), Gaps = 3/81 (3%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWR--NRFVAVKHINSEA-EKREFAIEVRQLSRVCH 191
E++ ++I +G G +G V++GVW+ + VAVK + + E EF E + + H
Sbjct: 255 EMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKH 314
Query: 192 PNIVRLYGACTRGAHVCLVME 254
PN+V+L G CTR ++ E
Sbjct: 315 PNLVQLLGVCTREPPFYIITE 335
Score = 33.1 bits (72), Expect = 0.93
Identities = 11/28 (39%), Positives = 20/28 (71%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEV 600
W APE + ++ K DV+++G++LWE+
Sbjct: 424 WTAPESLAYNKFSIKSDVWAFGVLLWEI 451
>AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1130
Score = 50.4 bits (115), Expect = 6e-06
Identities = 27/81 (33%), Positives = 45/81 (55%), Gaps = 3/81 (3%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWR--NRFVAVKHINSEA-EKREFAIEVRQLSRVCH 191
E++ ++I +G G +G V++GVW+ + VAVK + + E EF E + + H
Sbjct: 236 EMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKH 295
Query: 192 PNIVRLYGACTRGAHVCLVME 254
PN+V+L G CTR ++ E
Sbjct: 296 PNLVQLLGVCTREPPFYIITE 316
Score = 33.1 bits (72), Expect = 0.93
Identities = 11/28 (39%), Positives = 20/28 (71%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEV 600
W APE + ++ K DV+++G++LWE+
Sbjct: 405 WTAPESLAYNKFSIKSDVWAFGVLLWEI 432
>AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 isoform b variant
protein.
Length = 1167
Score = 50.4 bits (115), Expect = 6e-06
Identities = 27/81 (33%), Positives = 45/81 (55%), Gaps = 3/81 (3%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWR--NRFVAVKHINSEA-EKREFAIEVRQLSRVCH 191
E++ ++I +G G +G V++GVW+ + VAVK + + E EF E + + H
Sbjct: 273 EMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKH 332
Query: 192 PNIVRLYGACTRGAHVCLVME 254
PN+V+L G CTR ++ E
Sbjct: 333 PNLVQLLGVCTREPPFYIITE 353
Score = 33.1 bits (72), Expect = 0.93
Identities = 11/28 (39%), Positives = 20/28 (71%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEV 600
W APE + ++ K DV+++G++LWE+
Sbjct: 442 WTAPESLAYNKFSIKSDVWAFGVLLWEI 469
>X52192-1|CAA36438.1| 822|Homo sapiens c-fes protein.
Length = 822
Score = 50.0 bits (114), Expect = 8e-06
Identities = 30/72 (41%), Positives = 39/72 (54%), Gaps = 5/72 (6%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWR--NRFVAVKHINSEAE---KREFAIEVRQLSRVCHPNIVRLYGAC 221
+G+G FG V+ G R N VAVK K +F E R L + HPNIVRL G C
Sbjct: 567 IGRGNFGEVFSGRLRADNTLVAVKSCRETLPPDLKAKFLQEARILKQYSHPNIVRLIGVC 626
Query: 222 TRGAHVCLVMEM 257
T+ + +VME+
Sbjct: 627 TQKQPIYIVMEL 638
Score = 37.1 bits (82), Expect = 0.057
Identities = 14/30 (46%), Positives = 19/30 (63%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE Y+ + DV+S+GI+LWE S
Sbjct: 726 WTAPEALNYGRYSSESDVWSFGILLWETFS 755
>X06292-1|CAA29619.1| 822|Homo sapiens NCP92 protein.
Length = 822
Score = 50.0 bits (114), Expect = 8e-06
Identities = 30/72 (41%), Positives = 39/72 (54%), Gaps = 5/72 (6%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWR--NRFVAVKHINSEAE---KREFAIEVRQLSRVCHPNIVRLYGAC 221
+G+G FG V+ G R N VAVK K +F E R L + HPNIVRL G C
Sbjct: 567 IGRGNFGEVFSGRLRADNTLVAVKSCRETLPPDLKAKFLQEARILKQYSHPNIVRLIGVC 626
Query: 222 TRGAHVCLVMEM 257
T+ + +VME+
Sbjct: 627 TQKQPIYIVMEL 638
Score = 37.1 bits (82), Expect = 0.057
Identities = 14/30 (46%), Positives = 19/30 (63%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE Y+ + DV+S+GI+LWE S
Sbjct: 726 WTAPEALNYGRYSSESDVWSFGILLWETFS 755
>BC036021-1|AAH36021.1| 662|Homo sapiens BMP2 inducible kinase
protein.
Length = 662
Score = 50.0 bits (114), Expect = 8e-06
Identities = 27/72 (37%), Positives = 40/72 (55%)
Frame = +2
Query: 266 GSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQR 445
G + N ++ + + +T + E VA LH K P+IHRDLK N+LL GG
Sbjct: 136 GQVVNQMNKKLQTGFTEPEVLQIFCDTCEAVARLHQCKT-PIIHRDLKVENILLNDGGNY 194
Query: 446 LKICDFGTAADK 481
+ +CDFG+A +K
Sbjct: 195 V-LCDFGSATNK 205
>BC035357-1|AAH35357.1| 822|Homo sapiens feline sarcoma oncogene
protein.
Length = 822
Score = 50.0 bits (114), Expect = 8e-06
Identities = 30/72 (41%), Positives = 39/72 (54%), Gaps = 5/72 (6%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWR--NRFVAVKHINSEAE---KREFAIEVRQLSRVCHPNIVRLYGAC 221
+G+G FG V+ G R N VAVK K +F E R L + HPNIVRL G C
Sbjct: 567 IGRGNFGEVFSGRLRADNTLVAVKSCRETLPPDLKAKFLQEARILKQYSHPNIVRLIGVC 626
Query: 222 TRGAHVCLVMEM 257
T+ + +VME+
Sbjct: 627 TQKQPIYIVMEL 638
Score = 37.1 bits (82), Expect = 0.057
Identities = 14/30 (46%), Positives = 19/30 (63%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE Y+ + DV+S+GI+LWE S
Sbjct: 726 WTAPEALNYGRYSSESDVWSFGILLWETFS 755
>AY513657-1|AAS82869.1| 752|Homo sapiens proto-oncogene c-fes
variant 4 protein.
Length = 752
Score = 50.0 bits (114), Expect = 8e-06
Identities = 30/72 (41%), Positives = 39/72 (54%), Gaps = 5/72 (6%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWR--NRFVAVKHINSEAE---KREFAIEVRQLSRVCHPNIVRLYGAC 221
+G+G FG V+ G R N VAVK K +F E R L + HPNIVRL G C
Sbjct: 497 IGRGNFGEVFSGRLRADNTLVAVKSCRETLPPDLKAKFLQEARILKQYSHPNIVRLIGVC 556
Query: 222 TRGAHVCLVMEM 257
T+ + +VME+
Sbjct: 557 TQKQPIYIVMEL 568
Score = 37.1 bits (82), Expect = 0.057
Identities = 14/30 (46%), Positives = 19/30 (63%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE Y+ + DV+S+GI+LWE S
Sbjct: 656 WTAPEALNYGRYSSESDVWSFGILLWETFS 685
>AY513656-1|AAS82868.1| 764|Homo sapiens proto-oncogene c-fes
variant 3 protein.
Length = 764
Score = 50.0 bits (114), Expect = 8e-06
Identities = 30/72 (41%), Positives = 39/72 (54%), Gaps = 5/72 (6%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWR--NRFVAVKHINSEAE---KREFAIEVRQLSRVCHPNIVRLYGAC 221
+G+G FG V+ G R N VAVK K +F E R L + HPNIVRL G C
Sbjct: 509 IGRGNFGEVFSGRLRADNTLVAVKSCRETLPPDLKAKFLQEARILKQYSHPNIVRLIGVC 568
Query: 222 TRGAHVCLVMEM 257
T+ + +VME+
Sbjct: 569 TQKQPIYIVMEL 580
Score = 37.1 bits (82), Expect = 0.057
Identities = 14/30 (46%), Positives = 19/30 (63%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE Y+ + DV+S+GI+LWE S
Sbjct: 668 WTAPEALNYGRYSSESDVWSFGILLWETFS 697
>AY513654-1|AAS82866.1| 694|Homo sapiens proto-oncogene c-fes
variant 1 protein.
Length = 694
Score = 50.0 bits (114), Expect = 8e-06
Identities = 30/72 (41%), Positives = 39/72 (54%), Gaps = 5/72 (6%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWR--NRFVAVKHINSEAE---KREFAIEVRQLSRVCHPNIVRLYGAC 221
+G+G FG V+ G R N VAVK K +F E R L + HPNIVRL G C
Sbjct: 439 IGRGNFGEVFSGRLRADNTLVAVKSCRETLPPDLKAKFLQEARILKQYSHPNIVRLIGVC 498
Query: 222 TRGAHVCLVMEM 257
T+ + +VME+
Sbjct: 499 TQKQPIYIVMEL 510
Score = 37.1 bits (82), Expect = 0.057
Identities = 14/30 (46%), Positives = 19/30 (63%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE Y+ + DV+S+GI+LWE S
Sbjct: 598 WTAPEALNYGRYSSESDVWSFGILLWETFS 627
>AL137661-1|CAB70863.1| 661|Homo sapiens hypothetical protein
protein.
Length = 661
Score = 50.0 bits (114), Expect = 8e-06
Identities = 27/72 (37%), Positives = 40/72 (55%)
Frame = +2
Query: 266 GSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQR 445
G + N ++ + + +T + E VA LH K P+IHRDLK N+LL GG
Sbjct: 136 GQVVNQMNKKLQTGFTEPEVLQIFCDTCEAVARLHQCKT-PIIHRDLKVENILLNDGGNY 194
Query: 446 LKICDFGTAADK 481
+ +CDFG+A +K
Sbjct: 195 V-LCDFGSATNK 205
>AL121829-14|CAC15526.1| 488|Homo sapiens protein ( ne kinase, the
PTK6 gene for ).).
Length = 488
Score = 50.0 bits (114), Expect = 8e-06
Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 2/85 (2%)
Frame = +3
Query: 15 VEEIDYSEIQELSVVGKGAFGVVWKGVWRNRF-VAVKHINSEAEK-REFAIEVRQLSRVC 188
V E +SE +G+G FG VW+G+W VA+K I S K + A E++ L +
Sbjct: 222 VWERPHSEFALGRKLGEGYFGEVWEGLWLGSLPVAIKVIKSANMKLTDLAKEIQTLKGLR 281
Query: 189 HPNIVRLYGACTRGAHVCLVMEMQK 263
H ++RL+ C+ G V +V E+ +
Sbjct: 282 HERLIRLHAVCSGGEPVYIVTELMR 306
Score = 31.9 bits (69), Expect = 2.2
Identities = 12/30 (40%), Positives = 20/30 (66%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE +++K DV+S+G++L EV +
Sbjct: 392 WTAPEAANYRVFSQKSDVWSFGVLLHEVFT 421
>AC098818-1|AAY40926.1| 662|Homo sapiens unknown protein.
Length = 662
Score = 50.0 bits (114), Expect = 8e-06
Identities = 27/72 (37%), Positives = 40/72 (55%)
Frame = +2
Query: 266 GSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQR 445
G + N ++ + + +T + E VA LH K P+IHRDLK N+LL GG
Sbjct: 136 GQVVNQMNKKLQTGFTEPEVLQIFCDTCEAVARLHQCKT-PIIHRDLKVENILLNDGGNY 194
Query: 446 LKICDFGTAADK 481
+ +CDFG+A +K
Sbjct: 195 V-LCDFGSATNK 205
>Z84466-8|CAI42468.1| 606|Homo sapiens v-raf murine sarcoma 3611
viral oncogene homolog protein.
Length = 606
Score = 49.6 bits (113), Expect = 1e-05
Identities = 32/77 (41%), Positives = 43/77 (55%)
Frame = +2
Query: 260 EGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGG 439
EG SLY+ LH ++ + ARQ A+G+ YLH+ K +IHRDLK N+ L G
Sbjct: 386 EGSSLYHHLHVADT-RFDMVQLIDVARQTAQGMDYLHA---KNIIHRDLKSNNIFL-HEG 440
Query: 440 QRLKICDFGTAADKATY 490
+KI DFG A K +
Sbjct: 441 LTVKIGDFGLATVKTRW 457
Score = 39.9 bits (89), Expect = 0.008
Identities = 25/73 (34%), Positives = 39/73 (53%), Gaps = 4/73 (5%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHIN----SEAEKREFAIEVRQLSRVC 188
E+ SE+Q L +G G+FG V++G W VAVK + + + + F E++ L +
Sbjct: 304 EVPPSEVQLLKRIGTGSFGTVFRGRWHGD-VAVKVLKVSQPTAEQAQAFKNEMQVLRKTR 362
Query: 189 HPNIVRLYGACTR 227
H NI+ G TR
Sbjct: 363 HVNILLFMGFMTR 375
Score = 30.7 bits (66), Expect = 5.0
Identities = 12/38 (31%), Positives = 26/38 (68%), Gaps = 3/38 (7%)
Frame = +1
Query: 517 WMAPEVF---EGSTYTEKCDVFSWGIILWEVLSRRKPF 621
WMA EV + + Y+ + DV+++G++L+E+++ P+
Sbjct: 472 WMAAEVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPY 509
>X04790-1|CAA28476.1| 606|Homo sapiens protein ( Human mRNA for
A-raf-1 oncogene. ).
Length = 606
Score = 49.6 bits (113), Expect = 1e-05
Identities = 32/77 (41%), Positives = 43/77 (55%)
Frame = +2
Query: 260 EGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGG 439
EG SLY+ LH ++ + ARQ A+G+ YLH+ K +IHRDLK N+ L G
Sbjct: 386 EGSSLYHHLHVADT-RFDMVQLIDVARQTAQGMDYLHA---KNIIHRDLKSNNIFL-HEG 440
Query: 440 QRLKICDFGTAADKATY 490
+KI DFG A K +
Sbjct: 441 LTVKIGDFGLATVKTRW 457
Score = 39.9 bits (89), Expect = 0.008
Identities = 25/73 (34%), Positives = 39/73 (53%), Gaps = 4/73 (5%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHIN----SEAEKREFAIEVRQLSRVC 188
E+ SE+Q L +G G+FG V++G W VAVK + + + + F E++ L +
Sbjct: 304 EVPPSEVQLLKRIGTGSFGTVFRGRWHGD-VAVKVLKVSQPTAEQAQAFKNEMQVLRKTR 362
Query: 189 HPNIVRLYGACTR 227
H NI+ G TR
Sbjct: 363 HVNILLFMGFMTR 375
Score = 30.7 bits (66), Expect = 5.0
Identities = 12/38 (31%), Positives = 26/38 (68%), Gaps = 3/38 (7%)
Frame = +1
Query: 517 WMAPEVF---EGSTYTEKCDVFSWGIILWEVLSRRKPF 621
WMA EV + + Y+ + DV+++G++L+E+++ P+
Sbjct: 472 WMAAEVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPY 509
>U01337-1|AAB03517.1| 606|Homo sapiens Ser/Thr protein kinase
protein.
Length = 606
Score = 49.6 bits (113), Expect = 1e-05
Identities = 32/77 (41%), Positives = 43/77 (55%)
Frame = +2
Query: 260 EGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGG 439
EG SLY+ LH ++ + ARQ A+G+ YLH+ K +IHRDLK N+ L G
Sbjct: 386 EGSSLYHHLHVADT-RFDMVQLIDVARQTAQGMDYLHA---KNIIHRDLKSNNIFL-HEG 440
Query: 440 QRLKICDFGTAADKATY 490
+KI DFG A K +
Sbjct: 441 LTVKIGDFGLATVKTRW 457
Score = 39.9 bits (89), Expect = 0.008
Identities = 25/73 (34%), Positives = 39/73 (53%), Gaps = 4/73 (5%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHIN----SEAEKREFAIEVRQLSRVC 188
E+ SE+Q L +G G+FG V++G W VAVK + + + + F E++ L +
Sbjct: 304 EVPPSEVQLLKRIGTGSFGTVFRGRWHGD-VAVKVLKVSQPTAEQAQAFKNEMQVLRKTR 362
Query: 189 HPNIVRLYGACTR 227
H NI+ G TR
Sbjct: 363 HVNILLFMGFMTR 375
Score = 30.7 bits (66), Expect = 5.0
Identities = 12/38 (31%), Positives = 26/38 (68%), Gaps = 3/38 (7%)
Frame = +1
Query: 517 WMAPEVF---EGSTYTEKCDVFSWGIILWEVLSRRKPF 621
WMA EV + + Y+ + DV+++G++L+E+++ P+
Sbjct: 472 WMAAEVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPY 509
>M13829-1|AAB08754.1| 298|Homo sapiens raf related protein protein.
Length = 298
Score = 49.6 bits (113), Expect = 1e-05
Identities = 32/77 (41%), Positives = 43/77 (55%)
Frame = +2
Query: 260 EGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGG 439
EG SLY+ LH ++ + ARQ A+G+ YLH+ K +IHRDLK N+ L G
Sbjct: 95 EGSSLYHHLHVADT-RFDMVQLIDVARQTAQGMDYLHA---KNIIHRDLKSNNIFL-HEG 149
Query: 440 QRLKICDFGTAADKATY 490
+KI DFG A K +
Sbjct: 150 LTVKIGDFGLATVKTRW 166
Score = 39.9 bits (89), Expect = 0.008
Identities = 25/73 (34%), Positives = 39/73 (53%), Gaps = 4/73 (5%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHIN----SEAEKREFAIEVRQLSRVC 188
E+ SE+Q L +G G+FG V++G W VAVK + + + + F E++ L +
Sbjct: 13 EVPPSEVQLLKRIGTGSFGTVFRGRWHGD-VAVKVLKVSQPTAEQAQAFKNEMQVLRKTR 71
Query: 189 HPNIVRLYGACTR 227
H NI+ G TR
Sbjct: 72 HVNILPFMGFMTR 84
Score = 29.9 bits (64), Expect = 8.7
Identities = 12/38 (31%), Positives = 26/38 (68%), Gaps = 3/38 (7%)
Frame = +1
Query: 517 WMAPEVF---EGSTYTEKCDVFSWGIILWEVLSRRKPF 621
WMA EV + + Y+ + DV+++G++L+E+++ P+
Sbjct: 181 WMAAEVTRMQDPNPYSFQSDVYAYGVVLYELMTGSLPY 218
>L41939-1|AAA99310.1| 987|Homo sapiens protein-tyrosine kinase
protein.
Length = 987
Score = 49.6 bits (113), Expect = 1e-05
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVW-----RNRFVAVKHINS---EAEKREFAIEV 167
F +EID S ++ V+G G FG V G R FVA+K + S E ++R+F E
Sbjct: 613 FAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEA 672
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPN++ L G T+ V ++ E +
Sbjct: 673 SIMGQFDHPNVIHLEGVVTKSTPVMIITEFME 704
Score = 39.1 bits (87), Expect = 0.014
Identities = 14/30 (46%), Positives = 21/30 (70%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE + +T DV+S+GI++WEV+S
Sbjct: 793 WTAPEAIQYRKFTSASDVWSYGIVMWEVMS 822
>L36643-1|AAA74244.1| 970|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 970
Score = 49.6 bits (113), Expect = 1e-05
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVW-----RNRFVAVKHINS---EAEKREFAIEV 167
F +EID S ++ V+G G FG V G R FVA+K + S E ++R+F E
Sbjct: 596 FAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEA 655
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPN++ L G T+ V ++ E +
Sbjct: 656 SIMGQFDHPNVIHLEGVVTKSTPVMIITEFME 687
Score = 39.1 bits (87), Expect = 0.014
Identities = 14/30 (46%), Positives = 21/30 (70%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE + +T DV+S+GI++WEV+S
Sbjct: 776 WTAPEAIQYRKFTSASDVWSYGIVMWEVMS 805
>L36642-1|AAA74243.1| 998|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 998
Score = 49.6 bits (113), Expect = 1e-05
Identities = 32/92 (34%), Positives = 49/92 (53%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVW-----RNRFVAVKHIN---SEAEKREFAIEV 167
F +E+D S I+ V+G G FG V G R+ VA+K + +E ++R+F E
Sbjct: 624 FAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEA 683
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPN+V L G TRG V +V+E +
Sbjct: 684 SIMGQFDHPNVVHLEGVVTRGKPVMIVIEFME 715
Score = 39.1 bits (87), Expect = 0.014
Identities = 14/30 (46%), Positives = 21/30 (70%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE + +T DV+S+GI++WEV+S
Sbjct: 802 WTAPEAIQYRKFTSASDVWSYGIVMWEVMS 831
>L24038-1|AAA65219.1| 606|Homo sapiens ARAF1 protein.
Length = 606
Score = 49.6 bits (113), Expect = 1e-05
Identities = 32/77 (41%), Positives = 43/77 (55%)
Frame = +2
Query: 260 EGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGG 439
EG SLY+ LH ++ + ARQ A+G+ YLH+ K +IHRDLK N+ L G
Sbjct: 386 EGSSLYHHLHVADT-RFDMVQLIDVARQTAQGMDYLHA---KNIIHRDLKSNNIFL-HEG 440
Query: 440 QRLKICDFGTAADKATY 490
+KI DFG A K +
Sbjct: 441 LTVKIGDFGLATVKTRW 457
Score = 39.9 bits (89), Expect = 0.008
Identities = 25/73 (34%), Positives = 39/73 (53%), Gaps = 4/73 (5%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHIN----SEAEKREFAIEVRQLSRVC 188
E+ SE+Q L +G G+FG V++G W VAVK + + + + F E++ L +
Sbjct: 304 EVPPSEVQLLKRIGTGSFGTVFRGRWHGD-VAVKVLKVSQPTAEQAQAFKNEMQVLRKTR 362
Query: 189 HPNIVRLYGACTR 227
H NI+ G TR
Sbjct: 363 HVNILLFMGFMTR 375
Score = 30.7 bits (66), Expect = 5.0
Identities = 12/38 (31%), Positives = 26/38 (68%), Gaps = 3/38 (7%)
Frame = +1
Query: 517 WMAPEVF---EGSTYTEKCDVFSWGIILWEVLSRRKPF 621
WMA EV + + Y+ + DV+++G++L+E+++ P+
Sbjct: 472 WMAAEVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPY 509
>D37827-1|BAA07073.1| 478|Homo sapiens large erk/cek5 tyrosine
kinase protein.
Length = 478
Score = 49.6 bits (113), Expect = 1e-05
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVW-----RNRFVAVKHINS---EAEKREFAIEV 167
F +EID S ++ V+G G FG V G R FVA+K + S E ++R+F E
Sbjct: 104 FAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEA 163
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPN++ L G T+ V ++ E +
Sbjct: 164 SIMGQFDHPNVIHLEGVVTKSTPVMIITEFME 195
Score = 39.1 bits (87), Expect = 0.014
Identities = 14/30 (46%), Positives = 21/30 (70%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE + +T DV+S+GI++WEV+S
Sbjct: 284 WTAPEAIQYRKFTSASDVWSYGIVMWEVMS 313
>D31661-1|BAA06506.1| 981|Homo sapiens tyrosine kinase precursor
protein.
Length = 981
Score = 49.6 bits (113), Expect = 1e-05
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVW-----RNRFVAVKHINS---EAEKREFAIEV 167
F +EID S ++ V+G G FG V G R FVA+K + S E ++R+F E
Sbjct: 607 FAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEA 666
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPN++ L G T+ V ++ E +
Sbjct: 667 SIMGQFDHPNVIHLEGVVTKSTPVMIITEFME 698
Score = 39.1 bits (87), Expect = 0.014
Identities = 14/30 (46%), Positives = 21/30 (70%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE + +T DV+S+GI++WEV+S
Sbjct: 787 WTAPEAIQYRKFTSASDVWSYGIVMWEVMS 816
>BT019864-1|AAV38667.1| 606|Homo sapiens v-raf murine sarcoma 3611
viral oncogene homolog 1 protein.
Length = 606
Score = 49.6 bits (113), Expect = 1e-05
Identities = 32/77 (41%), Positives = 43/77 (55%)
Frame = +2
Query: 260 EGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGG 439
EG SLY+ LH ++ + ARQ A+G+ YLH+ K +IHRDLK N+ L G
Sbjct: 386 EGSSLYHHLHVADT-RFDMVQLIDVARQTAQGMDYLHA---KNIIHRDLKSNNIFL-HEG 440
Query: 440 QRLKICDFGTAADKATY 490
+KI DFG A K +
Sbjct: 441 LTVKIGDFGLATVKTRW 457
Score = 39.9 bits (89), Expect = 0.008
Identities = 25/73 (34%), Positives = 39/73 (53%), Gaps = 4/73 (5%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHIN----SEAEKREFAIEVRQLSRVC 188
E+ SE+Q L +G G+FG V++G W VAVK + + + + F E++ L +
Sbjct: 304 EVPPSEVQLLKRIGTGSFGTVFRGRWHGD-VAVKVLKVSQPTAEQAQAFKNEMQVLRKTR 362
Query: 189 HPNIVRLYGACTR 227
H NI+ G TR
Sbjct: 363 HVNILLFMGFMTR 375
Score = 30.7 bits (66), Expect = 5.0
Identities = 12/38 (31%), Positives = 26/38 (68%), Gaps = 3/38 (7%)
Frame = +1
Query: 517 WMAPEVF---EGSTYTEKCDVFSWGIILWEVLSRRKPF 621
WMA EV + + Y+ + DV+++G++L+E+++ P+
Sbjct: 472 WMAAEVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPY 509
>BC126151-1|AAI26152.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 49.6 bits (113), Expect = 1e-05
Identities = 32/92 (34%), Positives = 49/92 (53%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVW-----RNRFVAVKHIN---SEAEKREFAIEV 167
F +E+D S I+ V+G G FG V G R+ VA+K + +E ++R+F E
Sbjct: 624 FAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEA 683
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPN+V L G TRG V +V+E +
Sbjct: 684 SIMGQFDHPNVVHLEGVVTRGKPVMIVIEFME 715
Score = 39.1 bits (87), Expect = 0.014
Identities = 14/30 (46%), Positives = 21/30 (70%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE + +T DV+S+GI++WEV+S
Sbjct: 802 WTAPEAIQYRKFTSASDVWSYGIVMWEVMS 831
>BC126125-1|AAI26126.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 49.6 bits (113), Expect = 1e-05
Identities = 32/92 (34%), Positives = 49/92 (53%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVW-----RNRFVAVKHIN---SEAEKREFAIEV 167
F +E+D S I+ V+G G FG V G R+ VA+K + +E ++R+F E
Sbjct: 624 FAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEA 683
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPN+V L G TRG V +V+E +
Sbjct: 684 SIMGQFDHPNVVHLEGVVTRGKPVMIVIEFME 715
Score = 39.1 bits (87), Expect = 0.014
Identities = 14/30 (46%), Positives = 21/30 (70%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE + +T DV+S+GI++WEV+S
Sbjct: 802 WTAPEAIQYRKFTSASDVWSYGIVMWEVMS 831
>BC013316-1|AAH13316.1| 460|Homo sapiens interleukin-1
receptor-associated kinase 4 protein.
Length = 460
Score = 49.6 bits (113), Expect = 1e-05
Identities = 33/97 (34%), Positives = 50/97 (51%), Gaps = 7/97 (7%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKH------INSEAEKREFAIEVRQLSRVCHPNIVRLYGA 218
+G+G FGVV+KG N VAVK I +E K++F E++ +++ H N+V L G
Sbjct: 192 MGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGF 251
Query: 219 CTRGAHVCLV-MEMQKVALSIMYYTTDPNPNTQQHMQ 326
+ G +CLV + M +L D P HM+
Sbjct: 252 SSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMR 288
Score = 32.7 bits (71), Expect = 1.2
Identities = 13/31 (41%), Positives = 22/31 (70%)
Frame = +1
Query: 514 AWMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
A+MAPE G T K D++S+G++L E+++
Sbjct: 353 AYMAPEALRGEI-TPKSDIYSFGVVLLEIIT 382
Score = 29.9 bits (64), Expect = 8.7
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 3/52 (5%)
Frame = +2
Query: 326 MSWARQC--AEGVAY-LHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTA 472
+SW +C A+G A ++ + IHRD+K N+LL KI DFG A
Sbjct: 283 LSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILL-DEAFTAKISDFGLA 333
>BC007514-1|AAH07514.1| 609|Homo sapiens ARAF protein protein.
Length = 609
Score = 49.6 bits (113), Expect = 1e-05
Identities = 32/77 (41%), Positives = 43/77 (55%)
Frame = +2
Query: 260 EGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGG 439
EG SLY+ LH ++ + ARQ A+G+ YLH+ K +IHRDLK N+ L G
Sbjct: 389 EGSSLYHHLHVADT-RFDMVQLIDVARQTAQGMDYLHA---KNIIHRDLKSNNIFL-HEG 443
Query: 440 QRLKICDFGTAADKATY 490
+KI DFG A K +
Sbjct: 444 LTVKIGDFGLATVKTRW 460
Score = 39.9 bits (89), Expect = 0.008
Identities = 25/73 (34%), Positives = 39/73 (53%), Gaps = 4/73 (5%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHIN----SEAEKREFAIEVRQLSRVC 188
E+ SE+Q L +G G+FG V++G W VAVK + + + + F E++ L +
Sbjct: 307 EVPPSEVQLLKRIGTGSFGTVFRGRWHGD-VAVKVLKVSQPTAEQAQAFKNEMQVLRKTR 365
Query: 189 HPNIVRLYGACTR 227
H NI+ G TR
Sbjct: 366 HVNILLFMGFMTR 378
Score = 30.7 bits (66), Expect = 5.0
Identities = 12/38 (31%), Positives = 26/38 (68%), Gaps = 3/38 (7%)
Frame = +1
Query: 517 WMAPEVF---EGSTYTEKCDVFSWGIILWEVLSRRKPF 621
WMA EV + + Y+ + DV+++G++L+E+++ P+
Sbjct: 475 WMAAEVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPY 512
>BC002466-1|AAH02466.1| 606|Homo sapiens v-raf murine sarcoma 3611
viral oncogene homolog protein.
Length = 606
Score = 49.6 bits (113), Expect = 1e-05
Identities = 32/77 (41%), Positives = 43/77 (55%)
Frame = +2
Query: 260 EGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGG 439
EG SLY+ LH ++ + ARQ A+G+ YLH+ K +IHRDLK N+ L G
Sbjct: 386 EGSSLYHHLHVADT-RFDMVQLIDVARQTAQGMDYLHA---KNIIHRDLKSNNIFL-HEG 440
Query: 440 QRLKICDFGTAADKATY 490
+KI DFG A K +
Sbjct: 441 LTVKIGDFGLATVKTRW 457
Score = 39.9 bits (89), Expect = 0.008
Identities = 25/73 (34%), Positives = 39/73 (53%), Gaps = 4/73 (5%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHIN----SEAEKREFAIEVRQLSRVC 188
E+ SE+Q L +G G+FG V++G W VAVK + + + + F E++ L +
Sbjct: 304 EVPPSEVQLLKRIGTGSFGTVFRGRWHGD-VAVKVLKVSQPTAEQAQAFKNEMQVLRKTR 362
Query: 189 HPNIVRLYGACTR 227
H NI+ G TR
Sbjct: 363 HVNILLFMGFMTR 375
Score = 30.7 bits (66), Expect = 5.0
Identities = 12/38 (31%), Positives = 26/38 (68%), Gaps = 3/38 (7%)
Frame = +1
Query: 517 WMAPEVF---EGSTYTEKCDVFSWGIILWEVLSRRKPF 621
WMA EV + + Y+ + DV+++G++L+E+++ P+
Sbjct: 472 WMAAEVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPY 509
>AY730682-1|AAX22228.1| 460|Homo sapiens interleukin-1 receptor
associated kinase-4 protein.
Length = 460
Score = 49.6 bits (113), Expect = 1e-05
Identities = 33/97 (34%), Positives = 50/97 (51%), Gaps = 7/97 (7%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKH------INSEAEKREFAIEVRQLSRVCHPNIVRLYGA 218
+G+G FGVV+KG N VAVK I +E K++F E++ +++ H N+V L G
Sbjct: 192 MGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGF 251
Query: 219 CTRGAHVCLV-MEMQKVALSIMYYTTDPNPNTQQHMQ 326
+ G +CLV + M +L D P HM+
Sbjct: 252 SSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMR 288
Score = 32.7 bits (71), Expect = 1.2
Identities = 13/31 (41%), Positives = 22/31 (70%)
Frame = +1
Query: 514 AWMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
A+MAPE G T K D++S+G++L E+++
Sbjct: 353 AYMAPEALRGEI-TPKSDIYSFGVVLLEIIT 382
Score = 29.9 bits (64), Expect = 8.7
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 3/52 (5%)
Frame = +2
Query: 326 MSWARQC--AEGVAY-LHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTA 472
+SW +C A+G A ++ + IHRD+K N+LL KI DFG A
Sbjct: 283 LSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILL-DEAFTAKISDFGLA 333
>AY340967-1|AAR02363.1| 336|Homo sapiens interleukin-1
receptor-associated kinase 4 short form variant 4
protein.
Length = 336
Score = 49.6 bits (113), Expect = 1e-05
Identities = 33/97 (34%), Positives = 50/97 (51%), Gaps = 7/97 (7%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKH------INSEAEKREFAIEVRQLSRVCHPNIVRLYGA 218
+G+G FGVV+KG N VAVK I +E K++F E++ +++ H N+V L G
Sbjct: 68 MGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGF 127
Query: 219 CTRGAHVCLV-MEMQKVALSIMYYTTDPNPNTQQHMQ 326
+ G +CLV + M +L D P HM+
Sbjct: 128 SSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMR 164
Score = 32.7 bits (71), Expect = 1.2
Identities = 13/31 (41%), Positives = 22/31 (70%)
Frame = +1
Query: 514 AWMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
A+MAPE G T K D++S+G++L E+++
Sbjct: 229 AYMAPEALRGEI-TPKSDIYSFGVVLLEIIT 258
Score = 29.9 bits (64), Expect = 8.7
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 3/52 (5%)
Frame = +2
Query: 326 MSWARQC--AEGVAY-LHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTA 472
+SW +C A+G A ++ + IHRD+K N+LL KI DFG A
Sbjct: 159 LSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILL-DEAFTAKISDFGLA 209
>AY340966-1|AAR02362.1| 336|Homo sapiens interleukin-1
receptor-associated kinase 4 short form variant 3
protein.
Length = 336
Score = 49.6 bits (113), Expect = 1e-05
Identities = 33/97 (34%), Positives = 50/97 (51%), Gaps = 7/97 (7%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKH------INSEAEKREFAIEVRQLSRVCHPNIVRLYGA 218
+G+G FGVV+KG N VAVK I +E K++F E++ +++ H N+V L G
Sbjct: 68 MGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGF 127
Query: 219 CTRGAHVCLV-MEMQKVALSIMYYTTDPNPNTQQHMQ 326
+ G +CLV + M +L D P HM+
Sbjct: 128 SSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMR 164
Score = 32.7 bits (71), Expect = 1.2
Identities = 13/31 (41%), Positives = 22/31 (70%)
Frame = +1
Query: 514 AWMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
A+MAPE G T K D++S+G++L E+++
Sbjct: 229 AYMAPEALRGEI-TPKSDIYSFGVVLLEIIT 258
Score = 29.9 bits (64), Expect = 8.7
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 3/52 (5%)
Frame = +2
Query: 326 MSWARQC--AEGVAY-LHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTA 472
+SW +C A+G A ++ + IHRD+K N+LL KI DFG A
Sbjct: 159 LSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILL-DEAFTAKISDFGLA 209
>AY340965-1|AAR02361.1| 336|Homo sapiens interleukin-1
receptor-associated kinase 4 short form variant 2
protein.
Length = 336
Score = 49.6 bits (113), Expect = 1e-05
Identities = 33/97 (34%), Positives = 50/97 (51%), Gaps = 7/97 (7%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKH------INSEAEKREFAIEVRQLSRVCHPNIVRLYGA 218
+G+G FGVV+KG N VAVK I +E K++F E++ +++ H N+V L G
Sbjct: 68 MGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGF 127
Query: 219 CTRGAHVCLV-MEMQKVALSIMYYTTDPNPNTQQHMQ 326
+ G +CLV + M +L D P HM+
Sbjct: 128 SSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMR 164
Score = 32.7 bits (71), Expect = 1.2
Identities = 13/31 (41%), Positives = 22/31 (70%)
Frame = +1
Query: 514 AWMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
A+MAPE G T K D++S+G++L E+++
Sbjct: 229 AYMAPEALRGEI-TPKSDIYSFGVVLLEIIT 258
Score = 29.9 bits (64), Expect = 8.7
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 3/52 (5%)
Frame = +2
Query: 326 MSWARQC--AEGVAY-LHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTA 472
+SW +C A+G A ++ + IHRD+K N+LL KI DFG A
Sbjct: 159 LSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILL-DEAFTAKISDFGLA 209
>AY340964-1|AAR02360.1| 336|Homo sapiens interleukin-1
receptor-associated kinase 4 short form variant 1
protein.
Length = 336
Score = 49.6 bits (113), Expect = 1e-05
Identities = 33/97 (34%), Positives = 50/97 (51%), Gaps = 7/97 (7%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKH------INSEAEKREFAIEVRQLSRVCHPNIVRLYGA 218
+G+G FGVV+KG N VAVK I +E K++F E++ +++ H N+V L G
Sbjct: 68 MGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGF 127
Query: 219 CTRGAHVCLV-MEMQKVALSIMYYTTDPNPNTQQHMQ 326
+ G +CLV + M +L D P HM+
Sbjct: 128 SSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMR 164
Score = 32.7 bits (71), Expect = 1.2
Identities = 13/31 (41%), Positives = 22/31 (70%)
Frame = +1
Query: 514 AWMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
A+MAPE G T K D++S+G++L E+++
Sbjct: 229 AYMAPEALRGEI-TPKSDIYSFGVVLLEIIT 258
Score = 29.9 bits (64), Expect = 8.7
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 3/52 (5%)
Frame = +2
Query: 326 MSWARQC--AEGVAY-LHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTA 472
+SW +C A+G A ++ + IHRD+K N+LL KI DFG A
Sbjct: 159 LSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILL-DEAFTAKISDFGLA 209
>AY340963-1|AAR02359.1| 460|Homo sapiens interleukin-1
receptor-associated kinase 4 variant protein.
Length = 460
Score = 49.6 bits (113), Expect = 1e-05
Identities = 33/97 (34%), Positives = 50/97 (51%), Gaps = 7/97 (7%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKH------INSEAEKREFAIEVRQLSRVCHPNIVRLYGA 218
+G+G FGVV+KG N VAVK I +E K++F E++ +++ H N+V L G
Sbjct: 192 MGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGF 251
Query: 219 CTRGAHVCLV-MEMQKVALSIMYYTTDPNPNTQQHMQ 326
+ G +CLV + M +L D P HM+
Sbjct: 252 SSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMR 288
Score = 32.7 bits (71), Expect = 1.2
Identities = 13/31 (41%), Positives = 22/31 (70%)
Frame = +1
Query: 514 AWMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
A+MAPE G T K D++S+G++L E+++
Sbjct: 353 AYMAPEALRGEI-TPKSDIYSFGVVLLEIIT 382
Score = 29.9 bits (64), Expect = 8.7
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 3/52 (5%)
Frame = +2
Query: 326 MSWARQC--AEGVAY-LHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTA 472
+SW +C A+G A ++ + IHRD+K N+LL KI DFG A
Sbjct: 283 LSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILL-DEAFTAKISDFGLA 333
>AY340962-1|AAR02358.1| 460|Homo sapiens interleukin-1
receptor-associated kinase 4 protein.
Length = 460
Score = 49.6 bits (113), Expect = 1e-05
Identities = 33/97 (34%), Positives = 50/97 (51%), Gaps = 7/97 (7%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKH------INSEAEKREFAIEVRQLSRVCHPNIVRLYGA 218
+G+G FGVV+KG N VAVK I +E K++F E++ +++ H N+V L G
Sbjct: 192 MGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGF 251
Query: 219 CTRGAHVCLV-MEMQKVALSIMYYTTDPNPNTQQHMQ 326
+ G +CLV + M +L D P HM+
Sbjct: 252 SSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMR 288
Score = 32.7 bits (71), Expect = 1.2
Identities = 13/31 (41%), Positives = 22/31 (70%)
Frame = +1
Query: 514 AWMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
A+MAPE G T K D++S+G++L E+++
Sbjct: 353 AYMAPEALRGEI-TPKSDIYSFGVVLLEIIT 382
Score = 29.9 bits (64), Expect = 8.7
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 3/52 (5%)
Frame = +2
Query: 326 MSWARQC--AEGVAY-LHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTA 472
+SW +C A+G A ++ + IHRD+K N+LL KI DFG A
Sbjct: 283 LSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILL-DEAFTAKISDFGLA 333
>AY283670-1|AAP57089.1| 292|Homo sapiens interleukin-1 receptor
associated kinase 4 mutant form 1 protein.
Length = 292
Score = 49.6 bits (113), Expect = 1e-05
Identities = 33/97 (34%), Positives = 50/97 (51%), Gaps = 7/97 (7%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKH------INSEAEKREFAIEVRQLSRVCHPNIVRLYGA 218
+G+G FGVV+KG N VAVK I +E K++F E++ +++ H N+V L G
Sbjct: 192 MGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGF 251
Query: 219 CTRGAHVCLV-MEMQKVALSIMYYTTDPNPNTQQHMQ 326
+ G +CLV + M +L D P HM+
Sbjct: 252 SSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMR 288
>AY186092-1|AAN75440.1| 460|Homo sapiens interleukin-1
receptor-associated kinase 4 protein.
Length = 460
Score = 49.6 bits (113), Expect = 1e-05
Identities = 33/97 (34%), Positives = 50/97 (51%), Gaps = 7/97 (7%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKH------INSEAEKREFAIEVRQLSRVCHPNIVRLYGA 218
+G+G FGVV+KG N VAVK I +E K++F E++ +++ H N+V L G
Sbjct: 192 MGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGF 251
Query: 219 CTRGAHVCLV-MEMQKVALSIMYYTTDPNPNTQQHMQ 326
+ G +CLV + M +L D P HM+
Sbjct: 252 SSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMR 288
Score = 32.7 bits (71), Expect = 1.2
Identities = 13/31 (41%), Positives = 22/31 (70%)
Frame = +1
Query: 514 AWMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
A+MAPE G T K D++S+G++L E+++
Sbjct: 353 AYMAPEALRGEI-TPKSDIYSFGVVLLEIIT 382
Score = 29.9 bits (64), Expect = 8.7
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 3/52 (5%)
Frame = +2
Query: 326 MSWARQC--AEGVAY-LHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTA 472
+SW +C A+G A ++ + IHRD+K N+LL KI DFG A
Sbjct: 283 LSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILL-DEAFTAKISDFGLA 333
>AL591036-1|CAH73650.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 49.6 bits (113), Expect = 1e-05
Identities = 32/92 (34%), Positives = 49/92 (53%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVW-----RNRFVAVKHIN---SEAEKREFAIEV 167
F +E+D S I+ V+G G FG V G R+ VA+K + +E ++R+F E
Sbjct: 624 FAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEA 683
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPN+V L G TRG V +V+E +
Sbjct: 684 SIMGQFDHPNVVHLEGVVTRGKPVMIVIEFME 715
Score = 39.1 bits (87), Expect = 0.014
Identities = 14/30 (46%), Positives = 21/30 (70%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE + +T DV+S+GI++WEV+S
Sbjct: 802 WTAPEAIQYRKFTSASDVWSYGIVMWEVMS 831
>AL512444-4|CAI16429.1| 1055|Homo sapiens EPH receptor B2 protein.
Length = 1055
Score = 49.6 bits (113), Expect = 1e-05
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVW-----RNRFVAVKHINS---EAEKREFAIEV 167
F +EID S ++ V+G G FG V G R FVA+K + S E ++R+F E
Sbjct: 612 FAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEA 671
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPN++ L G T+ V ++ E +
Sbjct: 672 SIMGQFDHPNVIHLEGVVTKSTPVMIITEFME 703
Score = 39.1 bits (87), Expect = 0.014
Identities = 14/30 (46%), Positives = 21/30 (70%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE + +T DV+S+GI++WEV+S
Sbjct: 792 WTAPEAIQYRKFTSASDVWSYGIVMWEVMS 821
>AL512444-3|CAI16430.2| 986|Homo sapiens EPH receptor B2 protein.
Length = 986
Score = 49.6 bits (113), Expect = 1e-05
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVW-----RNRFVAVKHINS---EAEKREFAIEV 167
F +EID S ++ V+G G FG V G R FVA+K + S E ++R+F E
Sbjct: 612 FAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEA 671
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPN++ L G T+ V ++ E +
Sbjct: 672 SIMGQFDHPNVIHLEGVVTKSTPVMIITEFME 703
Score = 39.1 bits (87), Expect = 0.014
Identities = 14/30 (46%), Positives = 21/30 (70%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE + +T DV+S+GI++WEV+S
Sbjct: 792 WTAPEAIQYRKFTSASDVWSYGIVMWEVMS 821
>AL512444-2|CAI16428.1| 987|Homo sapiens EPH receptor B2 protein.
Length = 987
Score = 49.6 bits (113), Expect = 1e-05
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVW-----RNRFVAVKHINS---EAEKREFAIEV 167
F +EID S ++ V+G G FG V G R FVA+K + S E ++R+F E
Sbjct: 613 FAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEA 672
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPN++ L G T+ V ++ E +
Sbjct: 673 SIMGQFDHPNVIHLEGVVTKSTPVMIITEFME 704
Score = 39.1 bits (87), Expect = 0.014
Identities = 14/30 (46%), Positives = 21/30 (70%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE + +T DV+S+GI++WEV+S
Sbjct: 793 WTAPEAIQYRKFTSASDVWSYGIVMWEVMS 822
>AL512444-1|CAI16427.1| 946|Homo sapiens EPH receptor B2 protein.
Length = 946
Score = 49.6 bits (113), Expect = 1e-05
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVW-----RNRFVAVKHINS---EAEKREFAIEV 167
F +EID S ++ V+G G FG V G R FVA+K + S E ++R+F E
Sbjct: 607 FAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEA 666
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPN++ L G T+ V ++ E +
Sbjct: 667 SIMGQFDHPNVIHLEGVVTKSTPVMIITEFME 698
Score = 39.1 bits (87), Expect = 0.014
Identities = 14/30 (46%), Positives = 21/30 (70%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE + +T DV+S+GI++WEV+S
Sbjct: 787 WTAPEAIQYRKFTSASDVWSYGIVMWEVMS 816
>AL354857-1|CAH72780.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 49.6 bits (113), Expect = 1e-05
Identities = 32/92 (34%), Positives = 49/92 (53%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVW-----RNRFVAVKHIN---SEAEKREFAIEV 167
F +E+D S I+ V+G G FG V G R+ VA+K + +E ++R+F E
Sbjct: 624 FAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEA 683
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPN+V L G TRG V +V+E +
Sbjct: 684 SIMGQFDHPNVVHLEGVVTRGKPVMIVIEFME 715
Score = 39.1 bits (87), Expect = 0.014
Identities = 14/30 (46%), Positives = 21/30 (70%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE + +T DV+S+GI++WEV+S
Sbjct: 802 WTAPEAIQYRKFTSASDVWSYGIVMWEVMS 831
>AL158086-8|CAI22898.1| 1055|Homo sapiens EPH receptor B2 protein.
Length = 1055
Score = 49.6 bits (113), Expect = 1e-05
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVW-----RNRFVAVKHINS---EAEKREFAIEV 167
F +EID S ++ V+G G FG V G R FVA+K + S E ++R+F E
Sbjct: 612 FAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEA 671
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPN++ L G T+ V ++ E +
Sbjct: 672 SIMGQFDHPNVIHLEGVVTKSTPVMIITEFME 703
Score = 39.1 bits (87), Expect = 0.014
Identities = 14/30 (46%), Positives = 21/30 (70%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE + +T DV+S+GI++WEV+S
Sbjct: 792 WTAPEAIQYRKFTSASDVWSYGIVMWEVMS 821
>AL158086-7|CAI22899.2| 986|Homo sapiens EPH receptor B2 protein.
Length = 986
Score = 49.6 bits (113), Expect = 1e-05
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVW-----RNRFVAVKHINS---EAEKREFAIEV 167
F +EID S ++ V+G G FG V G R FVA+K + S E ++R+F E
Sbjct: 612 FAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEA 671
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPN++ L G T+ V ++ E +
Sbjct: 672 SIMGQFDHPNVIHLEGVVTKSTPVMIITEFME 703
Score = 39.1 bits (87), Expect = 0.014
Identities = 14/30 (46%), Positives = 21/30 (70%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE + +T DV+S+GI++WEV+S
Sbjct: 792 WTAPEAIQYRKFTSASDVWSYGIVMWEVMS 821
>AL158086-6|CAI22897.1| 987|Homo sapiens EPH receptor B2 protein.
Length = 987
Score = 49.6 bits (113), Expect = 1e-05
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVW-----RNRFVAVKHINS---EAEKREFAIEV 167
F +EID S ++ V+G G FG V G R FVA+K + S E ++R+F E
Sbjct: 613 FAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEA 672
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPN++ L G T+ V ++ E +
Sbjct: 673 SIMGQFDHPNVIHLEGVVTKSTPVMIITEFME 704
Score = 39.1 bits (87), Expect = 0.014
Identities = 14/30 (46%), Positives = 21/30 (70%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE + +T DV+S+GI++WEV+S
Sbjct: 793 WTAPEAIQYRKFTSASDVWSYGIVMWEVMS 822
>AL121966-2|CAI19722.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 49.6 bits (113), Expect = 1e-05
Identities = 32/92 (34%), Positives = 49/92 (53%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVW-----RNRFVAVKHIN---SEAEKREFAIEV 167
F +E+D S I+ V+G G FG V G R+ VA+K + +E ++R+F E
Sbjct: 624 FAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEA 683
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPN+V L G TRG V +V+E +
Sbjct: 684 SIMGQFDHPNVVHLEGVVTRGKPVMIVIEFME 715
Score = 39.1 bits (87), Expect = 0.014
Identities = 14/30 (46%), Positives = 21/30 (70%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE + +T DV+S+GI++WEV+S
Sbjct: 802 WTAPEAIQYRKFTSASDVWSYGIVMWEVMS 831
>AL035704-4|CAI22646.1| 1055|Homo sapiens EPH receptor B2 protein.
Length = 1055
Score = 49.6 bits (113), Expect = 1e-05
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVW-----RNRFVAVKHINS---EAEKREFAIEV 167
F +EID S ++ V+G G FG V G R FVA+K + S E ++R+F E
Sbjct: 612 FAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEA 671
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPN++ L G T+ V ++ E +
Sbjct: 672 SIMGQFDHPNVIHLEGVVTKSTPVMIITEFME 703
Score = 39.1 bits (87), Expect = 0.014
Identities = 14/30 (46%), Positives = 21/30 (70%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE + +T DV+S+GI++WEV+S
Sbjct: 792 WTAPEAIQYRKFTSASDVWSYGIVMWEVMS 821
>AL035704-3|CAI22647.2| 986|Homo sapiens EPH receptor B2 protein.
Length = 986
Score = 49.6 bits (113), Expect = 1e-05
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVW-----RNRFVAVKHINS---EAEKREFAIEV 167
F +EID S ++ V+G G FG V G R FVA+K + S E ++R+F E
Sbjct: 612 FAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEA 671
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPN++ L G T+ V ++ E +
Sbjct: 672 SIMGQFDHPNVIHLEGVVTKSTPVMIITEFME 703
Score = 39.1 bits (87), Expect = 0.014
Identities = 14/30 (46%), Positives = 21/30 (70%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE + +T DV+S+GI++WEV+S
Sbjct: 792 WTAPEAIQYRKFTSASDVWSYGIVMWEVMS 821
>AL035704-2|CAI22645.1| 987|Homo sapiens EPH receptor B2 protein.
Length = 987
Score = 49.6 bits (113), Expect = 1e-05
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVW-----RNRFVAVKHINS---EAEKREFAIEV 167
F +EID S ++ V+G G FG V G R FVA+K + S E ++R+F E
Sbjct: 613 FAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEA 672
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPN++ L G T+ V ++ E +
Sbjct: 673 SIMGQFDHPNVIHLEGVVTKSTPVMIITEFME 704
Score = 39.1 bits (87), Expect = 0.014
Identities = 14/30 (46%), Positives = 21/30 (70%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE + +T DV+S+GI++WEV+S
Sbjct: 793 WTAPEAIQYRKFTSASDVWSYGIVMWEVMS 822
>AL035704-1|CAI22644.1| 946|Homo sapiens EPH receptor B2 protein.
Length = 946
Score = 49.6 bits (113), Expect = 1e-05
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVW-----RNRFVAVKHINS---EAEKREFAIEV 167
F +EID S ++ V+G G FG V G R FVA+K + S E ++R+F E
Sbjct: 607 FAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEA 666
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPN++ L G T+ V ++ E +
Sbjct: 667 SIMGQFDHPNVIHLEGVVTKSTPVMIITEFME 698
Score = 39.1 bits (87), Expect = 0.014
Identities = 14/30 (46%), Positives = 21/30 (70%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE + +T DV+S+GI++WEV+S
Sbjct: 787 WTAPEAIQYRKFTSASDVWSYGIVMWEVMS 816
>AK027301-1|BAD12234.1| 277|Homo sapiens protein ( Homo sapiens
cDNA FLJ14395 fis, clone HEMBA1003250, weakly similar to
PROTEIN KINASE APK1A (EC 2.7.1.-). ).
Length = 277
Score = 49.6 bits (113), Expect = 1e-05
Identities = 33/97 (34%), Positives = 50/97 (51%), Gaps = 7/97 (7%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKH------INSEAEKREFAIEVRQLSRVCHPNIVRLYGA 218
+G+G FGVV+KG N VAVK I +E K++F E++ +++ H N+V L G
Sbjct: 68 MGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGF 127
Query: 219 CTRGAHVCLV-MEMQKVALSIMYYTTDPNPNTQQHMQ 326
+ G +CLV + M +L D P HM+
Sbjct: 128 SSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMR 164
Score = 32.7 bits (71), Expect = 1.2
Identities = 13/31 (41%), Positives = 22/31 (70%)
Frame = +1
Query: 514 AWMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
A+MAPE G T K D++S+G++L E+++
Sbjct: 229 AYMAPEALRGEI-TPKSDIYSFGVVLLEIIT 258
Score = 29.9 bits (64), Expect = 8.7
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 3/52 (5%)
Frame = +2
Query: 326 MSWARQC--AEGVAY-LHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTA 472
+SW +C A+G A ++ + IHRD+K N+LL KI DFG A
Sbjct: 159 LSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILL-DEAFTAKISDFGLA 209
>AK000528-1|BAA91232.1| 460|Homo sapiens protein ( Homo sapiens
cDNA FLJ20521 fis, clone KAT10395. ).
Length = 460
Score = 49.6 bits (113), Expect = 1e-05
Identities = 33/97 (34%), Positives = 50/97 (51%), Gaps = 7/97 (7%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKH------INSEAEKREFAIEVRQLSRVCHPNIVRLYGA 218
+G+G FGVV+KG N VAVK I +E K++F E++ +++ H N+V L G
Sbjct: 192 MGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGF 251
Query: 219 CTRGAHVCLV-MEMQKVALSIMYYTTDPNPNTQQHMQ 326
+ G +CLV + M +L D P HM+
Sbjct: 252 SSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMR 288
Score = 32.7 bits (71), Expect = 1.2
Identities = 13/31 (41%), Positives = 22/31 (70%)
Frame = +1
Query: 514 AWMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
A+MAPE G T K D++S+G++L E+++
Sbjct: 353 AYMAPEALRGEI-TPKSDIYSFGVVLLEIIT 382
Score = 29.9 bits (64), Expect = 8.7
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 3/52 (5%)
Frame = +2
Query: 326 MSWARQC--AEGVAY-LHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTA 472
+SW +C A+G A ++ + IHRD+K N+LL KI DFG A
Sbjct: 283 LSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILL-DEAFTAKISDFGLA 333
>AF445802-1|AAM15772.1| 460|Homo sapiens interleukin-1 receptor
associated kinase 4 protein.
Length = 460
Score = 49.6 bits (113), Expect = 1e-05
Identities = 33/97 (34%), Positives = 50/97 (51%), Gaps = 7/97 (7%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKH------INSEAEKREFAIEVRQLSRVCHPNIVRLYGA 218
+G+G FGVV+KG N VAVK I +E K++F E++ +++ H N+V L G
Sbjct: 192 MGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGF 251
Query: 219 CTRGAHVCLV-MEMQKVALSIMYYTTDPNPNTQQHMQ 326
+ G +CLV + M +L D P HM+
Sbjct: 252 SSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMR 288
Score = 32.7 bits (71), Expect = 1.2
Identities = 13/31 (41%), Positives = 22/31 (70%)
Frame = +1
Query: 514 AWMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
A+MAPE G T K D++S+G++L E+++
Sbjct: 353 AYMAPEALRGEI-TPKSDIYSFGVVLLEIIT 382
Score = 29.9 bits (64), Expect = 8.7
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 3/52 (5%)
Frame = +2
Query: 326 MSWARQC--AEGVAY-LHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTA 472
+SW +C A+G A ++ + IHRD+K N+LL KI DFG A
Sbjct: 283 LSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILL-DEAFTAKISDFGLA 333
>AF155118-1|AAD42884.1| 460|Homo sapiens putative protein kinase
NY-REN-64 antigen protein.
Length = 460
Score = 49.6 bits (113), Expect = 1e-05
Identities = 33/97 (34%), Positives = 50/97 (51%), Gaps = 7/97 (7%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKH------INSEAEKREFAIEVRQLSRVCHPNIVRLYGA 218
+G+G FGVV+KG N VAVK I +E K++F E++ +++ H N+V L G
Sbjct: 192 MGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGF 251
Query: 219 CTRGAHVCLV-MEMQKVALSIMYYTTDPNPNTQQHMQ 326
+ G +CLV + M +L D P HM+
Sbjct: 252 SSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMR 288
Score = 32.7 bits (71), Expect = 1.2
Identities = 13/31 (41%), Positives = 22/31 (70%)
Frame = +1
Query: 514 AWMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
A+MAPE G T K D++S+G++L E+++
Sbjct: 353 AYMAPEALRGEI-TPKSDIYSFGVVLLEIIT 382
Score = 29.9 bits (64), Expect = 8.7
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 3/52 (5%)
Frame = +2
Query: 326 MSWARQC--AEGVAY-LHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTA 472
+SW +C A+G A ++ + IHRD+K N+LL KI DFG A
Sbjct: 283 LSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILL-DEAFTAKISDFGLA 333
>AF025304-1|AAB94602.1| 1055|Homo sapiens protein-tyrosine kinase
EPHB2v protein.
Length = 1055
Score = 49.6 bits (113), Expect = 1e-05
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVW-----RNRFVAVKHINS---EAEKREFAIEV 167
F +EID S ++ V+G G FG V G R FVA+K + S E ++R+F E
Sbjct: 612 FAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEA 671
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPN++ L G T+ V ++ E +
Sbjct: 672 SIMGQFDHPNVIHLEGVVTKSTPVMIITEFME 703
Score = 39.1 bits (87), Expect = 0.014
Identities = 14/30 (46%), Positives = 21/30 (70%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE + +T DV+S+GI++WEV+S
Sbjct: 792 WTAPEAIQYRKFTSASDVWSYGIVMWEVMS 821
>AB210018-1|BAE06100.1| 1004|Homo sapiens EPHB2 variant protein
protein.
Length = 1004
Score = 49.6 bits (113), Expect = 1e-05
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVW-----RNRFVAVKHINS---EAEKREFAIEV 167
F +EID S ++ V+G G FG V G R FVA+K + S E ++R+F E
Sbjct: 630 FAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEA 689
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPN++ L G T+ V ++ E +
Sbjct: 690 SIMGQFDHPNVIHLEGVVTKSTPVMIITEFME 721
Score = 39.1 bits (87), Expect = 0.014
Identities = 14/30 (46%), Positives = 21/30 (70%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE + +T DV+S+GI++WEV+S
Sbjct: 810 WTAPEAIQYRKFTSASDVWSYGIVMWEVMS 839
>AB209269-1|BAD92506.1| 1000|Homo sapiens ephrin receptor EphA7
variant protein.
Length = 1000
Score = 49.6 bits (113), Expect = 1e-05
Identities = 32/92 (34%), Positives = 49/92 (53%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVW-----RNRFVAVKHIN---SEAEKREFAIEV 167
F +E+D S I+ V+G G FG V G R+ VA+K + +E ++R+F E
Sbjct: 626 FAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEA 685
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPN+V L G TRG V +V+E +
Sbjct: 686 SIMGQFDHPNVVHLEGVVTRGKPVMIVIEFME 717
Score = 39.1 bits (87), Expect = 0.014
Identities = 14/30 (46%), Positives = 21/30 (70%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE + +T DV+S+GI++WEV+S
Sbjct: 804 WTAPEAIQYRKFTSASDVWSYGIVMWEVMS 833
>J03358-1|AAA61190.1| 822|Homo sapiens FER protein.
Length = 822
Score = 49.2 bits (112), Expect = 1e-05
Identities = 28/72 (38%), Positives = 43/72 (59%), Gaps = 4/72 (5%)
Frame = +3
Query: 54 VVGKGAFGVVWKGVWRNRF-VAVKHINSEAE---KREFAIEVRQLSRVCHPNIVRLYGAC 221
++GKG FG V+KG +++ VAVK + K +F E + L + HPNIV+L G C
Sbjct: 568 LLGKGNFGEVYKGTLKDKTSVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVC 627
Query: 222 TRGAHVCLVMEM 257
T+ V ++ME+
Sbjct: 628 TQRQPVYIIMEL 639
Score = 37.1 bits (82), Expect = 0.057
Identities = 14/30 (46%), Positives = 19/30 (63%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE Y+ + DV+S+GI+LWE S
Sbjct: 726 WTAPEALNYGRYSSESDVWSFGILLWETFS 755
>DQ822519-1|ABG46944.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 49.2 bits (112), Expect = 1e-05
Identities = 25/71 (35%), Positives = 42/71 (59%), Gaps = 5/71 (7%)
Frame = +3
Query: 24 IDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVK--HINSEAEKREFAIEVRQLSRVC--- 188
+ SEI+ ++G G+FG V+KG RN+ VA+K N+ K + + R++S +C
Sbjct: 458 LQLSEIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCREVSILCQLN 517
Query: 189 HPNIVRLYGAC 221
HP +++ GAC
Sbjct: 518 HPCVIQFVGAC 528
Score = 46.4 bits (105), Expect = 9e-05
Identities = 21/36 (58%), Positives = 25/36 (69%), Gaps = 1/36 (2%)
Frame = +1
Query: 517 WMAPEVFEGST-YTEKCDVFSWGIILWEVLSRRKPF 621
WMAPEVF T YT K DVFS+ + LWE+L+ PF
Sbjct: 630 WMAPEVFTQCTRYTIKADVFSYALCLWEILTGEIPF 665
Score = 44.8 bits (101), Expect = 3e-04
Identities = 26/68 (38%), Positives = 40/68 (58%)
Frame = +2
Query: 263 GGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQ 442
GGSL+++LH + K + A A+G+ YLH++ +P+IHRDL N+LL G
Sbjct: 544 GGSLFSLLHEQ-KRILDLQSKLIIAVDVAKGMEYLHNLT-QPIIHRDLNSHNILLYEDGH 601
Query: 443 RLKICDFG 466
+ + DFG
Sbjct: 602 AV-VADFG 608
>BX640903-1|CAE45949.1| 714|Homo sapiens hypothetical protein
protein.
Length = 714
Score = 49.2 bits (112), Expect = 1e-05
Identities = 25/71 (35%), Positives = 42/71 (59%), Gaps = 5/71 (7%)
Frame = +3
Query: 24 IDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVK--HINSEAEKREFAIEVRQLSRVC--- 188
+ SEI+ ++G G+FG V+KG RN+ VA+K N+ K + + R++S +C
Sbjct: 576 LQLSEIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCREVSILCQLN 635
Query: 189 HPNIVRLYGAC 221
HP +++ GAC
Sbjct: 636 HPCVIQFVGAC 646
>BX470253-1|CAI16293.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 49.2 bits (112), Expect = 1e-05
Identities = 25/71 (35%), Positives = 42/71 (59%), Gaps = 5/71 (7%)
Frame = +3
Query: 24 IDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVK--HINSEAEKREFAIEVRQLSRVC--- 188
+ SEI+ ++G G+FG V+KG RN+ VA+K N+ K + + R++S +C
Sbjct: 458 LQLSEIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCREVSILCQLN 517
Query: 189 HPNIVRLYGAC 221
HP +++ GAC
Sbjct: 518 HPCVIQFVGAC 528
Score = 46.4 bits (105), Expect = 9e-05
Identities = 21/36 (58%), Positives = 25/36 (69%), Gaps = 1/36 (2%)
Frame = +1
Query: 517 WMAPEVFEGST-YTEKCDVFSWGIILWEVLSRRKPF 621
WMAPEVF T YT K DVFS+ + LWE+L+ PF
Sbjct: 630 WMAPEVFTQCTRYTIKADVFSYALCLWEILTGEIPF 665
Score = 44.8 bits (101), Expect = 3e-04
Identities = 26/68 (38%), Positives = 40/68 (58%)
Frame = +2
Query: 263 GGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQ 442
GGSL+++LH + K + A A+G+ YLH++ +P+IHRDL N+LL G
Sbjct: 544 GGSLFSLLHEQ-KRILDLQSKLIIAVDVAKGMEYLHNLT-QPIIHRDLNSHNILLYEDGH 601
Query: 443 RLKICDFG 466
+ + DFG
Sbjct: 602 AV-VADFG 608
>BC117262-1|AAI17263.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 49.2 bits (112), Expect = 1e-05
Identities = 25/71 (35%), Positives = 42/71 (59%), Gaps = 5/71 (7%)
Frame = +3
Query: 24 IDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVK--HINSEAEKREFAIEVRQLSRVC--- 188
+ SEI+ ++G G+FG V+KG RN+ VA+K N+ K + + R++S +C
Sbjct: 458 LQLSEIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCREVSILCQLN 517
Query: 189 HPNIVRLYGAC 221
HP +++ GAC
Sbjct: 518 HPCVIQFVGAC 528
Score = 46.4 bits (105), Expect = 9e-05
Identities = 21/36 (58%), Positives = 25/36 (69%), Gaps = 1/36 (2%)
Frame = +1
Query: 517 WMAPEVFEGST-YTEKCDVFSWGIILWEVLSRRKPF 621
WMAPEVF T YT K DVFS+ + LWE+L+ PF
Sbjct: 630 WMAPEVFTQCTRYTIKADVFSYALCLWEILTGEIPF 665
Score = 44.8 bits (101), Expect = 3e-04
Identities = 26/68 (38%), Positives = 40/68 (58%)
Frame = +2
Query: 263 GGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQ 442
GGSL+++LH + K + A A+G+ YLH++ +P+IHRDL N+LL G
Sbjct: 544 GGSLFSLLHEQ-KRILDLQSKLIIAVDVAKGMEYLHNLT-QPIIHRDLNSHNILLYEDGH 601
Query: 443 RLKICDFG 466
+ + DFG
Sbjct: 602 AV-VADFG 608
>BC113539-1|AAI13540.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 49.2 bits (112), Expect = 1e-05
Identities = 25/71 (35%), Positives = 42/71 (59%), Gaps = 5/71 (7%)
Frame = +3
Query: 24 IDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVK--HINSEAEKREFAIEVRQLSRVC--- 188
+ SEI+ ++G G+FG V+KG RN+ VA+K N+ K + + R++S +C
Sbjct: 458 LQLSEIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCREVSILCQLN 517
Query: 189 HPNIVRLYGAC 221
HP +++ GAC
Sbjct: 518 HPCVIQFVGAC 528
Score = 46.4 bits (105), Expect = 9e-05
Identities = 21/36 (58%), Positives = 25/36 (69%), Gaps = 1/36 (2%)
Frame = +1
Query: 517 WMAPEVFEGST-YTEKCDVFSWGIILWEVLSRRKPF 621
WMAPEVF T YT K DVFS+ + LWE+L+ PF
Sbjct: 630 WMAPEVFTQCTRYTIKADVFSYALCLWEILTGEIPF 665
Score = 44.8 bits (101), Expect = 3e-04
Identities = 26/68 (38%), Positives = 40/68 (58%)
Frame = +2
Query: 263 GGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQ 442
GGSL+++LH + K + A A+G+ YLH++ +P+IHRDL N+LL G
Sbjct: 544 GGSLFSLLHEQ-KRILDLQSKLIIAVDVAKGMEYLHNLT-QPIIHRDLNSHNILLYEDGH 601
Query: 443 RLKICDFG 466
+ + DFG
Sbjct: 602 AV-VADFG 608
>BC032865-1|AAH32865.1| 843|Homo sapiens TNNI3K protein protein.
Length = 843
Score = 49.2 bits (112), Expect = 1e-05
Identities = 25/71 (35%), Positives = 42/71 (59%), Gaps = 5/71 (7%)
Frame = +3
Query: 24 IDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVK--HINSEAEKREFAIEVRQLSRVC--- 188
+ SEI+ ++G G+FG V+KG RN+ VA+K N+ K + + R++S +C
Sbjct: 559 LQLSEIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCREVSILCQLN 618
Query: 189 HPNIVRLYGAC 221
HP +++ GAC
Sbjct: 619 HPCVIQFVGAC 629
Score = 46.4 bits (105), Expect = 9e-05
Identities = 21/36 (58%), Positives = 25/36 (69%), Gaps = 1/36 (2%)
Frame = +1
Query: 517 WMAPEVFEGST-YTEKCDVFSWGIILWEVLSRRKPF 621
WMAPEVF T YT K DVFS+ + LWE+L+ PF
Sbjct: 731 WMAPEVFTQCTRYTIKADVFSYALCLWEILTGEIPF 766
Score = 44.8 bits (101), Expect = 3e-04
Identities = 26/68 (38%), Positives = 40/68 (58%)
Frame = +2
Query: 263 GGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQ 442
GGSL+++LH + K + A A+G+ YLH++ +P+IHRDL N+LL G
Sbjct: 645 GGSLFSLLHEQ-KRILDLQSKLIIAVDVAKGMEYLHNLT-QPIIHRDLNSHNILLYEDGH 702
Query: 443 RLKICDFG 466
+ + DFG
Sbjct: 703 AV-VADFG 709
>AY303691-1|AAP72030.1| 835|Homo sapiens cardiac ankyrin repeat
kinase protein.
Length = 835
Score = 49.2 bits (112), Expect = 1e-05
Identities = 25/71 (35%), Positives = 42/71 (59%), Gaps = 5/71 (7%)
Frame = +3
Query: 24 IDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVK--HINSEAEKREFAIEVRQLSRVC--- 188
+ SEI+ ++G G+FG V+KG RN+ VA+K N+ K + + R++S +C
Sbjct: 458 LQLSEIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCREVSILCQLN 517
Query: 189 HPNIVRLYGAC 221
HP +++ GAC
Sbjct: 518 HPCVIQFVGAC 528
Score = 46.4 bits (105), Expect = 9e-05
Identities = 21/36 (58%), Positives = 25/36 (69%), Gaps = 1/36 (2%)
Frame = +1
Query: 517 WMAPEVFEGST-YTEKCDVFSWGIILWEVLSRRKPF 621
WMAPEVF T YT K DVFS+ + LWE+L+ PF
Sbjct: 630 WMAPEVFTQCTRYTIKADVFSYALCLWEILTGEIPF 665
Score = 44.8 bits (101), Expect = 3e-04
Identities = 26/68 (38%), Positives = 40/68 (58%)
Frame = +2
Query: 263 GGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQ 442
GGSL+++LH + K + A A+G+ YLH++ +P+IHRDL N+LL G
Sbjct: 544 GGSLFSLLHEQ-KRILDLQSKLIIAVDVAKGMEYLHNLT-QPIIHRDLNSHNILLYEDGH 601
Query: 443 RLKICDFG 466
+ + DFG
Sbjct: 602 AV-VADFG 608
>AF116826-1|AAD29632.1| 835|Homo sapiens putative protein-tyrosine
kinase protein.
Length = 835
Score = 49.2 bits (112), Expect = 1e-05
Identities = 25/71 (35%), Positives = 42/71 (59%), Gaps = 5/71 (7%)
Frame = +3
Query: 24 IDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVK--HINSEAEKREFAIEVRQLSRVC--- 188
+ SEI+ ++G G+FG V+KG RN+ VA+K N+ K + + R++S +C
Sbjct: 458 LQLSEIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCREVSILCQLN 517
Query: 189 HPNIVRLYGAC 221
HP +++ GAC
Sbjct: 518 HPCVIQFVGAC 528
Score = 46.4 bits (105), Expect = 9e-05
Identities = 21/36 (58%), Positives = 25/36 (69%), Gaps = 1/36 (2%)
Frame = +1
Query: 517 WMAPEVFEGST-YTEKCDVFSWGIILWEVLSRRKPF 621
WMAPEVF T YT K DVFS+ + LWE+L+ PF
Sbjct: 630 WMAPEVFTQCTRYTIKADVFSYALCLWEILTGEIPF 665
Score = 44.8 bits (101), Expect = 3e-04
Identities = 26/68 (38%), Positives = 40/68 (58%)
Frame = +2
Query: 263 GGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQ 442
GGSL+++LH + K + A A+G+ YLH++ +P+IHRDL N+LL G
Sbjct: 544 GGSLFSLLHEQ-KRILDLQSKLIIAVDVAKGMEYLHNLT-QPIIHRDLNSHNILLYEDGH 601
Query: 443 RLKICDFG 466
+ + DFG
Sbjct: 602 AV-VADFG 608
>AB208941-1|BAD92178.1| 941|Homo sapiens TNNI3 interacting kinase
variant protein.
Length = 941
Score = 49.2 bits (112), Expect = 1e-05
Identities = 25/71 (35%), Positives = 42/71 (59%), Gaps = 5/71 (7%)
Frame = +3
Query: 24 IDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVK--HINSEAEKREFAIEVRQLSRVC--- 188
+ SEI+ ++G G+FG V+KG RN+ VA+K N+ K + + R++S +C
Sbjct: 564 LQLSEIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCREVSILCQLN 623
Query: 189 HPNIVRLYGAC 221
HP +++ GAC
Sbjct: 624 HPCVIQFVGAC 634
Score = 46.4 bits (105), Expect = 9e-05
Identities = 21/36 (58%), Positives = 25/36 (69%), Gaps = 1/36 (2%)
Frame = +1
Query: 517 WMAPEVFEGST-YTEKCDVFSWGIILWEVLSRRKPF 621
WMAPEVF T YT K DVFS+ + LWE+L+ PF
Sbjct: 736 WMAPEVFTQCTRYTIKADVFSYALCLWEILTGEIPF 771
Score = 44.8 bits (101), Expect = 3e-04
Identities = 26/68 (38%), Positives = 40/68 (58%)
Frame = +2
Query: 263 GGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQ 442
GGSL+++LH + K + A A+G+ YLH++ +P+IHRDL N+LL G
Sbjct: 650 GGSLFSLLHEQ-KRILDLQSKLIIAVDVAKGMEYLHNLT-QPIIHRDLNSHNILLYEDGH 707
Query: 443 RLKICDFG 466
+ + DFG
Sbjct: 708 AV-VADFG 714
>BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase
36, fused homolog (Drosophila) protein.
Length = 1315
Score = 48.8 bits (111), Expect = 2e-05
Identities = 33/91 (36%), Positives = 48/91 (52%), Gaps = 3/91 (3%)
Frame = +2
Query: 254 DAEGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVG 433
D G L+ +L + K A+ A Q + YLHS + ++HRD+KP N+LL
Sbjct: 81 DYAEGELFQILEDDGKLPEDQVQAI--AAQLVSALYYLHSHR---ILHRDMKPQNILLAK 135
Query: 434 GGQRLKICDFGTAADKAT---YMTNNKGVLL 517
GG +K+CDFG A +T +T+ KG L
Sbjct: 136 GG-GIKLCDFGFARAMSTNTMVLTSIKGTPL 165
Score = 35.9 bits (79), Expect = 0.13
Identities = 24/75 (32%), Positives = 39/75 (52%), Gaps = 6/75 (8%)
Frame = +3
Query: 48 LSVVGKGAFGVVWKG--VWRNRFVAVKHI----NSEAEKREFAIEVRQLSRVCHPNIVRL 209
L ++G+G+FG V+KG + + VA+K I SE E R E+ + + HPNIV +
Sbjct: 7 LEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRHPNIVHM 66
Query: 210 YGACTRGAHVCLVME 254
+ V +V +
Sbjct: 67 LDSFETDKEVVVVTD 81
>AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine
kinase protein.
Length = 1315
Score = 48.8 bits (111), Expect = 2e-05
Identities = 33/91 (36%), Positives = 48/91 (52%), Gaps = 3/91 (3%)
Frame = +2
Query: 254 DAEGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVG 433
D G L+ +L + K A+ A Q + YLHS + ++HRD+KP N+LL
Sbjct: 81 DYAEGELFQILEDDGKLPEDQVQAI--AAQLVSALYYLHSHR---ILHRDMKPQNILLAK 135
Query: 434 GGQRLKICDFGTAADKAT---YMTNNKGVLL 517
GG +K+CDFG A +T +T+ KG L
Sbjct: 136 GG-GIKLCDFGFARAMSTNTMVLTSIKGTPL 165
Score = 35.9 bits (79), Expect = 0.13
Identities = 24/75 (32%), Positives = 39/75 (52%), Gaps = 6/75 (8%)
Frame = +3
Query: 48 LSVVGKGAFGVVWKG--VWRNRFVAVKHI----NSEAEKREFAIEVRQLSRVCHPNIVRL 209
L ++G+G+FG V+KG + + VA+K I SE E R E+ + + HPNIV +
Sbjct: 7 LEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRHPNIVHM 66
Query: 210 YGACTRGAHVCLVME 254
+ V +V +
Sbjct: 67 LDSFETDKEVVVVTD 81
>AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein.
Length = 1311
Score = 48.8 bits (111), Expect = 2e-05
Identities = 33/91 (36%), Positives = 48/91 (52%), Gaps = 3/91 (3%)
Frame = +2
Query: 254 DAEGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVG 433
D G L+ +L + K A+ A Q + YLHS + ++HRD+KP N+LL
Sbjct: 98 DYAEGELFQILEDDGKLPEDQVQAI--AAQLVSALYYLHSHR---ILHRDMKPQNILLAK 152
Query: 434 GGQRLKICDFGTAADKAT---YMTNNKGVLL 517
GG +K+CDFG A +T +T+ KG L
Sbjct: 153 GG-GIKLCDFGFARAMSTNTMVLTSIKGTPL 182
Score = 35.9 bits (79), Expect = 0.13
Identities = 24/75 (32%), Positives = 39/75 (52%), Gaps = 6/75 (8%)
Frame = +3
Query: 48 LSVVGKGAFGVVWKG--VWRNRFVAVKHI----NSEAEKREFAIEVRQLSRVCHPNIVRL 209
L ++G+G+FG V+KG + + VA+K I SE E R E+ + + HPNIV +
Sbjct: 24 LEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRHPNIVHM 83
Query: 210 YGACTRGAHVCLVME 254
+ V +V +
Sbjct: 84 LDSFETDKEVVVVTD 98
>U50648-1|AAC50768.1| 551|Homo sapiens interferon-inducible
RNA-dependent protein kinase protein.
Length = 551
Score = 48.0 bits (109), Expect = 3e-05
Identities = 34/85 (40%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Frame = +2
Query: 266 GSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQR 445
G+L + R K A+ Q +GV Y+HS K LIHRDLKP N+ LV Q
Sbjct: 372 GTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKK---LIHRDLKPSNIFLVDTKQ- 427
Query: 446 LKICDFG--TAADKATYMTNNKGVL 514
+KI DFG T+ T +KG L
Sbjct: 428 VKIGDFGLVTSLKNDGKRTRSKGTL 452
Score = 36.3 bits (80), Expect = 0.10
Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Frame = +3
Query: 36 EIQELSVVGKGAFGVVWKGVWR--NRFVAVKHINSEAEKREFAIEVRQLSRVCHPNIVRL 209
+ +E+ ++G G FG V+K R + +K + EK E EV+ L+++ H NIV
Sbjct: 266 DFKEIELIGSGGFGQVFKAKHRIDGKTYVIKRVKYNNEKAE--REVKALAKLDHVNIVH- 322
Query: 210 YGACTRG 230
Y C G
Sbjct: 323 YNGCWDG 329
>M95712-1|AAA35609.2| 766|Homo sapiens B-raf protein protein.
Length = 766
Score = 48.0 bits (109), Expect = 3e-05
Identities = 32/77 (41%), Positives = 44/77 (57%)
Frame = +2
Query: 260 EGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGG 439
EG SLY+ LH + K+ + ARQ A+G+ YLH+ K +IHRDLK N+ L
Sbjct: 533 EGSSLYHHLHII-ETKFEMIKLIDIARQTAQGMDYLHA---KSIIHRDLKSNNIFL-HED 587
Query: 440 QRLKICDFGTAADKATY 490
+KI DFG A K+ +
Sbjct: 588 LTVKIGDFGLATVKSRW 604
Score = 37.1 bits (82), Expect = 0.057
Identities = 26/73 (35%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEA----EKREFAIEVRQLSRVC 188
EI +I +G G+FG V+KG W VAVK +N A + + F EV L +
Sbjct: 451 EIPDGQITVGQRIGSGSFGTVYKGKWHGD-VAVKMLNVTAPTPQQLQAFKNEVGVLRKTR 509
Query: 189 HPNIVRLYGACTR 227
H NI+ G T+
Sbjct: 510 HVNILLFMGYSTK 522
Score = 34.7 bits (76), Expect = 0.31
Identities = 14/38 (36%), Positives = 28/38 (73%), Gaps = 3/38 (7%)
Frame = +1
Query: 517 WMAPEVF---EGSTYTEKCDVFSWGIILWEVLSRRKPF 621
WMAPEV + + Y+ + DV+++GI+L+E+++ + P+
Sbjct: 619 WMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPY 656
>M85294-1|AAA18253.1| 551|Homo sapiens P1/eIF-2a protein kinase
protein.
Length = 551
Score = 48.0 bits (109), Expect = 3e-05
Identities = 34/85 (40%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Frame = +2
Query: 266 GSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQR 445
G+L + R K A+ Q +GV Y+HS K LIHRDLKP N+ LV Q
Sbjct: 372 GTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKK---LIHRDLKPSNIFLVDTKQ- 427
Query: 446 LKICDFG--TAADKATYMTNNKGVL 514
+KI DFG T+ T +KG L
Sbjct: 428 VKIGDFGLVTSLKNDGKRTRSKGTL 452
Score = 36.3 bits (80), Expect = 0.10
Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Frame = +3
Query: 36 EIQELSVVGKGAFGVVWKGVWR--NRFVAVKHINSEAEKREFAIEVRQLSRVCHPNIVRL 209
+ +E+ ++G G FG V+K R + +K + EK E EV+ L+++ H NIV
Sbjct: 266 DFKEIELIGSGGFGQVFKAKHRIDGKTYVIKRVKYNNEKAE--REVKALAKLDHVNIVH- 322
Query: 210 YGACTRG 230
Y C G
Sbjct: 323 YNGCWDG 329
>M35663-1|AAA36409.1| 551|Homo sapiens protein ( Human p68 kinase
mRNA, complete cds. ).
Length = 551
Score = 48.0 bits (109), Expect = 3e-05
Identities = 34/85 (40%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Frame = +2
Query: 266 GSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQR 445
G+L + R K A+ Q +GV Y+HS K LIHRDLKP N+ LV Q
Sbjct: 372 GTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKK---LIHRDLKPSNIFLVDTKQ- 427
Query: 446 LKICDFG--TAADKATYMTNNKGVL 514
+KI DFG T+ T +KG L
Sbjct: 428 VKIGDFGLVTSLKNDGKRTRSKGTL 452
Score = 36.3 bits (80), Expect = 0.10
Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Frame = +3
Query: 36 EIQELSVVGKGAFGVVWKGVWR--NRFVAVKHINSEAEKREFAIEVRQLSRVCHPNIVRL 209
+ +E+ ++G G FG V+K R + +K + EK E EV+ L+++ H NIV
Sbjct: 266 DFKEIELIGSGGFGQVFKAKHRIDGKTYVIKRVKYNNEKAE--REVKALAKLDHVNIVH- 322
Query: 210 YGACTRG 230
Y C G
Sbjct: 323 YNGCWDG 329
>M21001-1|AAA96495.1| 328|Homo sapiens B-raf protein protein.
Length = 328
Score = 48.0 bits (109), Expect = 3e-05
Identities = 32/77 (41%), Positives = 44/77 (57%)
Frame = +2
Query: 260 EGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGG 439
EG SLY+ LH + K+ + ARQ A+G+ YLH+ K +IHRDLK N+ L
Sbjct: 95 EGSSLYHHLHII-ETKFEMIKLIDIARQTAQGMDYLHA---KSIIHRDLKSNNIFL-HED 149
Query: 440 QRLKICDFGTAADKATY 490
+KI DFG A K+ +
Sbjct: 150 LTVKIGDFGLATVKSRW 166
Score = 37.1 bits (82), Expect = 0.057
Identities = 26/73 (35%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEA----EKREFAIEVRQLSRVC 188
EI +I +G G+FG V+KG W VAVK +N A + + F EV L +
Sbjct: 13 EIPDGQITVGQRIGSGSFGTVYKGKWHGD-VAVKMLNVTAPTPQQLQAFKNEVGVLRKTR 71
Query: 189 HPNIVRLYGACTR 227
H NI+ G T+
Sbjct: 72 HVNILLFMGYSTK 84
Score = 34.7 bits (76), Expect = 0.31
Identities = 14/38 (36%), Positives = 28/38 (73%), Gaps = 3/38 (7%)
Frame = +1
Query: 517 WMAPEVF---EGSTYTEKCDVFSWGIILWEVLSRRKPF 621
WMAPEV + + Y+ + DV+++GI+L+E+++ + P+
Sbjct: 181 WMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPY 218
>BC112079-1|AAI12080.1| 766|Homo sapiens v-raf murine sarcoma viral
oncogene homolog B1 protein.
Length = 766
Score = 48.0 bits (109), Expect = 3e-05
Identities = 32/77 (41%), Positives = 44/77 (57%)
Frame = +2
Query: 260 EGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGG 439
EG SLY+ LH + K+ + ARQ A+G+ YLH+ K +IHRDLK N+ L
Sbjct: 533 EGSSLYHHLHII-ETKFEMIKLIDIARQTAQGMDYLHA---KSIIHRDLKSNNIFL-HED 587
Query: 440 QRLKICDFGTAADKATY 490
+KI DFG A K+ +
Sbjct: 588 LTVKIGDFGLATVKSRW 604
Score = 37.1 bits (82), Expect = 0.057
Identities = 26/73 (35%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEA----EKREFAIEVRQLSRVC 188
EI +I +G G+FG V+KG W VAVK +N A + + F EV L +
Sbjct: 451 EIPDGQITVGQRIGSGSFGTVYKGKWHGD-VAVKMLNVTAPTPQQLQAFKNEVGVLRKTR 509
Query: 189 HPNIVRLYGACTR 227
H NI+ G T+
Sbjct: 510 HVNILLFMGYSTK 522
Score = 34.7 bits (76), Expect = 0.31
Identities = 14/38 (36%), Positives = 28/38 (73%), Gaps = 3/38 (7%)
Frame = +1
Query: 517 WMAPEVF---EGSTYTEKCDVFSWGIILWEVLSRRKPF 621
WMAPEV + + Y+ + DV+++GI+L+E+++ + P+
Sbjct: 619 WMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPY 656
>BC101757-1|AAI01758.1| 766|Homo sapiens v-raf murine sarcoma viral
oncogene homolog B1 protein.
Length = 766
Score = 48.0 bits (109), Expect = 3e-05
Identities = 32/77 (41%), Positives = 44/77 (57%)
Frame = +2
Query: 260 EGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGG 439
EG SLY+ LH + K+ + ARQ A+G+ YLH+ K +IHRDLK N+ L
Sbjct: 533 EGSSLYHHLHII-ETKFEMIKLIDIARQTAQGMDYLHA---KSIIHRDLKSNNIFL-HED 587
Query: 440 QRLKICDFGTAADKATY 490
+KI DFG A K+ +
Sbjct: 588 LTVKIGDFGLATVKSRW 604
Score = 37.1 bits (82), Expect = 0.057
Identities = 26/73 (35%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEA----EKREFAIEVRQLSRVC 188
EI +I +G G+FG V+KG W VAVK +N A + + F EV L +
Sbjct: 451 EIPDGQITVGQRIGSGSFGTVYKGKWHGD-VAVKMLNVTAPTPQQLQAFKNEVGVLRKTR 509
Query: 189 HPNIVRLYGACTR 227
H NI+ G T+
Sbjct: 510 HVNILLFMGYSTK 522
Score = 34.7 bits (76), Expect = 0.31
Identities = 14/38 (36%), Positives = 28/38 (73%), Gaps = 3/38 (7%)
Frame = +1
Query: 517 WMAPEVF---EGSTYTEKCDVFSWGIILWEVLSRRKPF 621
WMAPEV + + Y+ + DV+++GI+L+E+++ + P+
Sbjct: 619 WMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPY 656
>BC101475-1|AAI01476.1| 551|Homo sapiens eukaryotic translation
initiation factor 2-alpha kinase 2 protein.
Length = 551
Score = 48.0 bits (109), Expect = 3e-05
Identities = 34/85 (40%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Frame = +2
Query: 266 GSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQR 445
G+L + R K A+ Q +GV Y+HS K LIHRDLKP N+ LV Q
Sbjct: 372 GTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKK---LIHRDLKPSNIFLVDTKQ- 427
Query: 446 LKICDFG--TAADKATYMTNNKGVL 514
+KI DFG T+ T +KG L
Sbjct: 428 VKIGDFGLVTSLKNDGKRTRSKGTL 452
Score = 36.3 bits (80), Expect = 0.10
Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Frame = +3
Query: 36 EIQELSVVGKGAFGVVWKGVWR--NRFVAVKHINSEAEKREFAIEVRQLSRVCHPNIVRL 209
+ +E+ ++G G FG V+K R + +K + EK E EV+ L+++ H NIV
Sbjct: 266 DFKEIELIGSGGFGQVFKAKHRIDGKTYVIKRVKYNNEKAE--REVKALAKLDHVNIVH- 322
Query: 210 YGACTRG 230
Y C G
Sbjct: 323 YNGCWDG 329
>BC094862-1|AAH94862.1| 393|Homo sapiens WNK1 protein protein.
Length = 393
Score = 48.0 bits (109), Expect = 3e-05
Identities = 23/51 (45%), Positives = 31/51 (60%)
Frame = +2
Query: 329 SWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTAADK 481
SW RQ +G+ +LH+ P P+IHRDLK N+ + G +KI D G A K
Sbjct: 326 SWCRQILKGLQFLHTRTP-PIIHRDLKCDNIFITGPTGSVKIGDLGLATLK 375
Score = 33.5 bits (73), Expect = 0.71
Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 6/58 (10%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKHIN------SEAEKREFAIEVRQLSRVCHPNIVRLY 212
+G+G+F V+KG+ V V +++E++ F E L + HPNIVR Y
Sbjct: 227 IGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFY 284
>BC093676-1|AAH93676.1| 551|Homo sapiens eukaryotic translation
initiation factor 2-alpha kinase 2 protein.
Length = 551
Score = 48.0 bits (109), Expect = 3e-05
Identities = 34/85 (40%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Frame = +2
Query: 266 GSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQR 445
G+L + R K A+ Q +GV Y+HS K LIHRDLKP N+ LV Q
Sbjct: 372 GTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKK---LIHRDLKPSNIFLVDTKQ- 427
Query: 446 LKICDFG--TAADKATYMTNNKGVL 514
+KI DFG T+ T +KG L
Sbjct: 428 VKIGDFGLVTSLKNDGKRTRSKGTL 452
Score = 36.3 bits (80), Expect = 0.10
Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Frame = +3
Query: 36 EIQELSVVGKGAFGVVWKGVWR--NRFVAVKHINSEAEKREFAIEVRQLSRVCHPNIVRL 209
+ +E+ ++G G FG V+K R + +K + EK E EV+ L+++ H NIV
Sbjct: 266 DFKEIELIGSGGFGQVFKAKHRIDGKTYVIKRVKYNNEKAE--REVKALAKLDHVNIVH- 322
Query: 210 YGACTRG 230
Y C G
Sbjct: 323 YNGCWDG 329
>BC057805-1|AAH57805.1| 513|Homo sapiens EIF2AK2 protein protein.
Length = 513
Score = 48.0 bits (109), Expect = 3e-05
Identities = 34/85 (40%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Frame = +2
Query: 266 GSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQR 445
G+L + R K A+ Q +GV Y+HS K LIHRDLKP N+ LV Q
Sbjct: 372 GTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKK---LIHRDLKPSNIFLVDTKQ- 427
Query: 446 LKICDFG--TAADKATYMTNNKGVL 514
+KI DFG T+ T +KG L
Sbjct: 428 VKIGDFGLVTSLKNDGKRTRSKGTL 452
Score = 36.3 bits (80), Expect = 0.10
Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Frame = +3
Query: 36 EIQELSVVGKGAFGVVWKGVWR--NRFVAVKHINSEAEKREFAIEVRQLSRVCHPNIVRL 209
+ +E+ ++G G FG V+K R + +K + EK E EV+ L+++ H NIV
Sbjct: 266 DFKEIELIGSGGFGQVFKAKHRIDGKTYVIKRVKYNNEKAE--REVKALAKLDHVNIVH- 322
Query: 210 YGACTRG 230
Y C G
Sbjct: 323 YNGCWDG 329
>BC040851-1|AAH40851.1| 513|Homo sapiens EIF2AK2 protein protein.
Length = 513
Score = 48.0 bits (109), Expect = 3e-05
Identities = 34/85 (40%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Frame = +2
Query: 266 GSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQR 445
G+L + R K A+ Q +GV Y+HS K LIHRDLKP N+ LV Q
Sbjct: 372 GTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKK---LIHRDLKPSNIFLVDTKQ- 427
Query: 446 LKICDFG--TAADKATYMTNNKGVL 514
+KI DFG T+ T +KG L
Sbjct: 428 VKIGDFGLVTSLKNDGKRTRSKGTL 452
Score = 36.3 bits (80), Expect = 0.10
Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Frame = +3
Query: 36 EIQELSVVGKGAFGVVWKGVWR--NRFVAVKHINSEAEKREFAIEVRQLSRVCHPNIVRL 209
+ +E+ ++G G FG V+K R + +K + EK E EV+ L+++ H NIV
Sbjct: 266 DFKEIELIGSGGFGQVFKAKHRIDGKTYVIKRVKYNNEKAE--REVKALAKLDHVNIVH- 322
Query: 210 YGACTRG 230
Y C G
Sbjct: 323 YNGCWDG 329
>BC021121-1|AAH21121.1| 393|Homo sapiens WNK1 protein protein.
Length = 393
Score = 48.0 bits (109), Expect = 3e-05
Identities = 23/51 (45%), Positives = 31/51 (60%)
Frame = +2
Query: 329 SWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTAADK 481
SW RQ +G+ +LH+ P P+IHRDLK N+ + G +KI D G A K
Sbjct: 326 SWCRQILKGLQFLHTRTP-PIIHRDLKCDNIFITGPTGSVKIGDLGLATLK 375
Score = 33.5 bits (73), Expect = 0.71
Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 6/58 (10%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKHIN------SEAEKREFAIEVRQLSRVCHPNIVRLY 212
+G+G+F V+KG+ V V +++E++ F E L + HPNIVR Y
Sbjct: 227 IGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFY 284
>BC006524-1|AAH06524.1| 630|Homo sapiens eukaryotic translation
initiation factor 2-alpha kinase 1 protein.
Length = 630
Score = 48.0 bits (109), Expect = 3e-05
Identities = 27/61 (44%), Positives = 36/61 (59%), Gaps = 4/61 (6%)
Frame = +2
Query: 338 RQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTAA----DKATYMTNNK 505
++ EGV Y+H+M ++HRDLKP N+ L G Q++KI DFG A K T TN
Sbjct: 424 QELVEGVFYIHNMG---IVHRDLKPRNIFLHGPDQQVKIGDFGLACTDILQKNTDWTNRN 480
Query: 506 G 508
G
Sbjct: 481 G 481
Score = 36.3 bits (80), Expect = 0.10
Identities = 23/75 (30%), Positives = 40/75 (53%), Gaps = 6/75 (8%)
Frame = +3
Query: 33 SEIQELSVVGKGAFGVVWK--GVWRNRFVAVKHINSEAEKREFAI----EVRQLSRVCHP 194
+E +EL+++GKG +G V+K ++ A+K I + + + EV+ L+ + HP
Sbjct: 165 NEFEELAILGKGGYGRVYKVRNKLDGQYYAIKKILIKGATKTVCMKVLREVKVLAGLQHP 224
Query: 195 NIVRLYGACTRGAHV 239
NIV + A HV
Sbjct: 225 NIVGYHTAWIEHVHV 239
Score = 31.1 bits (67), Expect = 3.8
Identities = 12/28 (42%), Positives = 19/28 (67%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEV 600
+ +PE EGS Y K D++S G++L E+
Sbjct: 496 YASPEQLEGSEYDAKSDMYSLGVVLLEL 523
>AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion protein
protein.
Length = 1492
Score = 48.0 bits (109), Expect = 3e-05
Identities = 32/77 (41%), Positives = 44/77 (57%)
Frame = +2
Query: 260 EGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGG 439
EG SLY+ LH + K+ + ARQ A+G+ YLH+ K +IHRDLK N+ L
Sbjct: 1259 EGSSLYHHLHII-ETKFEMIKLIDIARQTAQGMDYLHA---KSIIHRDLKSNNIFL-HED 1313
Query: 440 QRLKICDFGTAADKATY 490
+KI DFG A K+ +
Sbjct: 1314 LTVKIGDFGLATVKSRW 1330
Score = 37.1 bits (82), Expect = 0.057
Identities = 26/73 (35%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEA----EKREFAIEVRQLSRVC 188
EI +I +G G+FG V+KG W VAVK +N A + + F EV L +
Sbjct: 1177 EIPDGQITVGQRIGSGSFGTVYKGKWHGD-VAVKMLNVTAPTPQQLQAFKNEVGVLRKTR 1235
Query: 189 HPNIVRLYGACTR 227
H NI+ G T+
Sbjct: 1236 HVNILLFMGYSTK 1248
Score = 34.7 bits (76), Expect = 0.31
Identities = 14/38 (36%), Positives = 28/38 (73%), Gaps = 3/38 (7%)
Frame = +1
Query: 517 WMAPEVF---EGSTYTEKCDVFSWGIILWEVLSRRKPF 621
WMAPEV + + Y+ + DV+++GI+L+E+++ + P+
Sbjct: 1345 WMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPY 1382
>AY302136-1|AAP57628.1| 510|Homo sapiens interferon-inducible
double-stranded RNA-dependent protein kinase protein.
Length = 510
Score = 48.0 bits (109), Expect = 3e-05
Identities = 34/85 (40%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Frame = +2
Query: 266 GSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQR 445
G+L + R K A+ Q +GV Y+HS K LIHRDLKP N+ LV Q
Sbjct: 331 GTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKK---LIHRDLKPSNIFLVDTKQ- 386
Query: 446 LKICDFG--TAADKATYMTNNKGVL 514
+KI DFG T+ T +KG L
Sbjct: 387 VKIGDFGLVTSLKNDGKRTRSKGTL 411
>AY228338-1|AAO38055.1| 551|Homo sapiens protein kinase,
interferon-inducible double stranded RNA dependent
protein.
Length = 551
Score = 48.0 bits (109), Expect = 3e-05
Identities = 34/85 (40%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Frame = +2
Query: 266 GSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQR 445
G+L + R K A+ Q +GV Y+HS K LIHRDLKP N+ LV Q
Sbjct: 372 GTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKK---LIHRDLKPSNIFLVDTKQ- 427
Query: 446 LKICDFG--TAADKATYMTNNKGVL 514
+KI DFG T+ T +KG L
Sbjct: 428 VKIGDFGLVTSLKNDGKRTRSKGTL 452
Score = 36.3 bits (80), Expect = 0.10
Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Frame = +3
Query: 36 EIQELSVVGKGAFGVVWKGVWR--NRFVAVKHINSEAEKREFAIEVRQLSRVCHPNIVRL 209
+ +E+ ++G G FG V+K R + +K + EK E EV+ L+++ H NIV
Sbjct: 266 DFKEIELIGSGGFGQVFKAKHRIDGKTYVIKRVKYNNEKAE--REVKALAKLDHVNIVH- 322
Query: 210 YGACTRG 230
Y C G
Sbjct: 323 YNGCWDG 329
>AL583839-7|CAO03350.1| 2219|Homo sapiens WNK lysine deficient
protein kinase 2 protein.
Length = 2219
Score = 48.0 bits (109), Expect = 3e-05
Identities = 23/51 (45%), Positives = 31/51 (60%)
Frame = +2
Query: 329 SWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTAADK 481
SW RQ +G+ +LH+ P P+IHRDLK N+ + G +KI D G A K
Sbjct: 295 SWCRQILKGLLFLHTRTP-PIIHRDLKCDNIFITGPTGSVKIGDLGLATLK 344
Score = 33.1 bits (72), Expect = 0.93
Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 6/58 (10%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKHIN------SEAEKREFAIEVRQLSRVCHPNIVRLY 212
+G+G+F V+KG+ +V V ++ E++ F E L + HPNIVR Y
Sbjct: 196 LGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFKEEAEMLKGLQHPNIVRFY 253
>AL583839-6|CAI12344.3| 2297|Homo sapiens WNK lysine deficient
protein kinase 2 protein.
Length = 2297
Score = 48.0 bits (109), Expect = 3e-05
Identities = 23/51 (45%), Positives = 31/51 (60%)
Frame = +2
Query: 329 SWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTAADK 481
SW RQ +G+ +LH+ P P+IHRDLK N+ + G +KI D G A K
Sbjct: 300 SWCRQILKGLLFLHTRTP-PIIHRDLKCDNIFITGPTGSVKIGDLGLATLK 349
Score = 33.1 bits (72), Expect = 0.93
Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 6/58 (10%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKHIN------SEAEKREFAIEVRQLSRVCHPNIVRLY 212
+G+G+F V+KG+ +V V ++ E++ F E L + HPNIVR Y
Sbjct: 201 LGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFKEEAEMLKGLQHPNIVRFY 258
>AL390760-3|CAO03647.1| 2219|Homo sapiens WNK lysine deficient
protein kinase 2 protein.
Length = 2219
Score = 48.0 bits (109), Expect = 3e-05
Identities = 23/51 (45%), Positives = 31/51 (60%)
Frame = +2
Query: 329 SWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTAADK 481
SW RQ +G+ +LH+ P P+IHRDLK N+ + G +KI D G A K
Sbjct: 295 SWCRQILKGLLFLHTRTP-PIIHRDLKCDNIFITGPTGSVKIGDLGLATLK 344
Score = 33.1 bits (72), Expect = 0.93
Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 6/58 (10%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKHIN------SEAEKREFAIEVRQLSRVCHPNIVRLY 212
+G+G+F V+KG+ +V V ++ E++ F E L + HPNIVR Y
Sbjct: 196 LGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFKEEAEMLKGLQHPNIVRFY 253
>AL390760-2|CAO03646.1| 790|Homo sapiens WNK lysine deficient
protein kinase 2 protein.
Length = 790
Score = 48.0 bits (109), Expect = 3e-05
Identities = 23/51 (45%), Positives = 31/51 (60%)
Frame = +2
Query: 329 SWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTAADK 481
SW RQ +G+ +LH+ P P+IHRDLK N+ + G +KI D G A K
Sbjct: 300 SWCRQILKGLLFLHTRTP-PIIHRDLKCDNIFITGPTGSVKIGDLGLATLK 349
Score = 33.1 bits (72), Expect = 0.93
Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 6/58 (10%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKHIN------SEAEKREFAIEVRQLSRVCHPNIVRLY 212
+G+G+F V+KG+ +V V ++ E++ F E L + HPNIVR Y
Sbjct: 201 LGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFKEEAEMLKGLQHPNIVRFY 258
>AL390760-1|CAH73069.3| 2297|Homo sapiens WNK lysine deficient
protein kinase 2 protein.
Length = 2297
Score = 48.0 bits (109), Expect = 3e-05
Identities = 23/51 (45%), Positives = 31/51 (60%)
Frame = +2
Query: 329 SWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTAADK 481
SW RQ +G+ +LH+ P P+IHRDLK N+ + G +KI D G A K
Sbjct: 300 SWCRQILKGLLFLHTRTP-PIIHRDLKCDNIFITGPTGSVKIGDLGLATLK 349
Score = 33.1 bits (72), Expect = 0.93
Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 6/58 (10%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKHIN------SEAEKREFAIEVRQLSRVCHPNIVRLY 212
+G+G+F V+KG+ +V V ++ E++ F E L + HPNIVR Y
Sbjct: 201 LGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFKEEAEMLKGLQHPNIVRFY 258
>AL354991-3|CAO03639.1| 2219|Homo sapiens WNK lysine deficient
protein kinase 2 protein.
Length = 2219
Score = 48.0 bits (109), Expect = 3e-05
Identities = 23/51 (45%), Positives = 31/51 (60%)
Frame = +2
Query: 329 SWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTAADK 481
SW RQ +G+ +LH+ P P+IHRDLK N+ + G +KI D G A K
Sbjct: 295 SWCRQILKGLLFLHTRTP-PIIHRDLKCDNIFITGPTGSVKIGDLGLATLK 344
Score = 33.1 bits (72), Expect = 0.93
Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 6/58 (10%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKHIN------SEAEKREFAIEVRQLSRVCHPNIVRLY 212
+G+G+F V+KG+ +V V ++ E++ F E L + HPNIVR Y
Sbjct: 196 LGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFKEEAEMLKGLQHPNIVRFY 253
>AL354991-2|CAI14449.3| 2297|Homo sapiens WNK lysine deficient
protein kinase 2 protein.
Length = 2297
Score = 48.0 bits (109), Expect = 3e-05
Identities = 23/51 (45%), Positives = 31/51 (60%)
Frame = +2
Query: 329 SWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTAADK 481
SW RQ +G+ +LH+ P P+IHRDLK N+ + G +KI D G A K
Sbjct: 300 SWCRQILKGLLFLHTRTP-PIIHRDLKCDNIFITGPTGSVKIGDLGLATLK 349
Score = 33.1 bits (72), Expect = 0.93
Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 6/58 (10%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKHIN------SEAEKREFAIEVRQLSRVCHPNIVRLY 212
+G+G+F V+KG+ +V V ++ E++ F E L + HPNIVR Y
Sbjct: 201 LGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFKEEAEMLKGLQHPNIVRFY 258
>AK075192-1|BAC11461.1| 630|Homo sapiens protein ( Homo sapiens
cDNA FLJ90711 fis, clone PLACE1008282, highly similar to
HEME-REGULATED EUKARYOTIC INITIATION FACTOR EIF-2-ALPHA
KINASE ).
Length = 630
Score = 48.0 bits (109), Expect = 3e-05
Identities = 27/61 (44%), Positives = 36/61 (59%), Gaps = 4/61 (6%)
Frame = +2
Query: 338 RQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTAA----DKATYMTNNK 505
++ EGV Y+H+M ++HRDLKP N+ L G Q++KI DFG A K T TN
Sbjct: 424 QELVEGVFYIHNMG---IVHRDLKPRNIFLHGPDQQVKIGDFGLACTDILQKNTDWTNRN 480
Query: 506 G 508
G
Sbjct: 481 G 481
Score = 36.3 bits (80), Expect = 0.10
Identities = 23/75 (30%), Positives = 40/75 (53%), Gaps = 6/75 (8%)
Frame = +3
Query: 33 SEIQELSVVGKGAFGVVWK--GVWRNRFVAVKHINSEAEKREFAI----EVRQLSRVCHP 194
+E +EL+++GKG +G V+K ++ A+K I + + + EV+ L+ + HP
Sbjct: 165 NEFEELAILGKGGYGRVYKVRNKLDGQYYAIKKILIKGATKTVCMKVLREVKVLAGLQHP 224
Query: 195 NIVRLYGACTRGAHV 239
NIV + A HV
Sbjct: 225 NIVGYHTAWIEHVHV 239
Score = 31.1 bits (67), Expect = 3.8
Identities = 12/28 (42%), Positives = 19/28 (67%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEV 600
+ +PE EGS Y K D++S G++L E+
Sbjct: 496 YASPEQLEGSEYDAKSDMYSLGVVLLEL 523
>AJ296290-1|CAC15059.1| 2382|Homo sapiens putative protein kinase
protein.
Length = 2382
Score = 48.0 bits (109), Expect = 3e-05
Identities = 23/51 (45%), Positives = 31/51 (60%)
Frame = +2
Query: 329 SWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTAADK 481
SW RQ +G+ +LH+ P P+IHRDLK N+ + G +KI D G A K
Sbjct: 326 SWCRQILKGLQFLHTRTP-PIIHRDLKCDNIFITGPTGSVKIGDLGLATLK 375
Score = 33.5 bits (73), Expect = 0.71
Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 6/58 (10%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKHIN------SEAEKREFAIEVRQLSRVCHPNIVRLY 212
+G+G+F V+KG+ V V +++E++ F E L + HPNIVR Y
Sbjct: 227 IGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFY 284
>AJ242724-1|CAB44308.5| 2297|Homo sapiens putative mitogen-activated
protein kinase kinase kinase protein.
Length = 2297
Score = 48.0 bits (109), Expect = 3e-05
Identities = 23/51 (45%), Positives = 31/51 (60%)
Frame = +2
Query: 329 SWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTAADK 481
SW RQ +G+ +LH+ P P+IHRDLK N+ + G +KI D G A K
Sbjct: 300 SWCRQILKGLLFLHTRTP-PIIHRDLKCDNIFITGPTGSVKIGDLGLATLK 349
Score = 33.1 bits (72), Expect = 0.93
Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 6/58 (10%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKHIN------SEAEKREFAIEVRQLSRVCHPNIVRLY 212
+G+G+F V+KG+ +V V ++ E++ F E L + HPNIVR Y
Sbjct: 201 LGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFKEEAEMLKGLQHPNIVRFY 258
>AF255050-1|AAF70289.1| 629|Homo sapiens heme-regulated eukaryotic
initiation factor 2 alpha kinase protein.
Length = 629
Score = 48.0 bits (109), Expect = 3e-05
Identities = 27/61 (44%), Positives = 36/61 (59%), Gaps = 4/61 (6%)
Frame = +2
Query: 338 RQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTAA----DKATYMTNNK 505
++ EGV Y+H+M ++HRDLKP N+ L G Q++KI DFG A K T TN
Sbjct: 423 QELVEGVFYIHNMG---IVHRDLKPRNIFLHGPDQQVKIGDFGLACTDILQKNTDWTNRN 479
Query: 506 G 508
G
Sbjct: 480 G 480
Score = 36.3 bits (80), Expect = 0.10
Identities = 23/75 (30%), Positives = 40/75 (53%), Gaps = 6/75 (8%)
Frame = +3
Query: 33 SEIQELSVVGKGAFGVVWK--GVWRNRFVAVKHINSEAEKREFAI----EVRQLSRVCHP 194
+E +EL+++GKG +G V+K ++ A+K I + + + EV+ L+ + HP
Sbjct: 164 NEFEELAILGKGGYGRVYKVRNKLDGQYYAIKKILIKGATKTVCMKVLREVKVLAGLQHP 223
Query: 195 NIVRLYGACTRGAHV 239
NIV + A HV
Sbjct: 224 NIVGYHTAWIEHVHV 238
Score = 31.1 bits (67), Expect = 3.8
Identities = 12/28 (42%), Positives = 19/28 (67%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEV 600
+ +PE EGS Y K D++S G++L E+
Sbjct: 495 YASPEQLEGSEYDAKSDMYSLGVVLLEL 522
>AF183414-1|AAG09683.1| 630|Homo sapiens hemin-sensitive initiation
factor 2a kinase protein.
Length = 630
Score = 48.0 bits (109), Expect = 3e-05
Identities = 27/61 (44%), Positives = 36/61 (59%), Gaps = 4/61 (6%)
Frame = +2
Query: 338 RQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTAA----DKATYMTNNK 505
++ EGV Y+H+M ++HRDLKP N+ L G Q++KI DFG A K T TN
Sbjct: 424 QELVEGVFYIHNMG---IVHRDLKPRNIFLHGPDQQVKIGDFGLACTDILQKNTDWTNRN 480
Query: 506 G 508
G
Sbjct: 481 G 481
Score = 36.3 bits (80), Expect = 0.10
Identities = 23/75 (30%), Positives = 40/75 (53%), Gaps = 6/75 (8%)
Frame = +3
Query: 33 SEIQELSVVGKGAFGVVWK--GVWRNRFVAVKHINSEAEKREFAI----EVRQLSRVCHP 194
+E +EL+++GKG +G V+K ++ A+K I + + + EV+ L+ + HP
Sbjct: 165 NEFEELAILGKGGYGRVYKVRNKLDGQYYAIKKILIKGATKTVCMKVLREVKVLAGLQHP 224
Query: 195 NIVRLYGACTRGAHV 239
NIV + A HV
Sbjct: 225 NIVGYHTAWIEHVHV 239
Score = 31.1 bits (67), Expect = 3.8
Identities = 12/28 (42%), Positives = 19/28 (67%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEV 600
+ +PE EGS Y K D++S G++L E+
Sbjct: 496 YASPEQLEGSEYDAKSDMYSLGVVLLEL 523
>AF181071-1|AAF18391.1| 630|Homo sapiens heme-regulated initiation
factor 2-alpha kinase protein.
Length = 630
Score = 48.0 bits (109), Expect = 3e-05
Identities = 27/61 (44%), Positives = 36/61 (59%), Gaps = 4/61 (6%)
Frame = +2
Query: 338 RQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTAA----DKATYMTNNK 505
++ EGV Y+H+M ++HRDLKP N+ L G Q++KI DFG A K T TN
Sbjct: 424 QELVEGVFYIHNMG---IVHRDLKPRNIFLHGPDQQVKIGDFGLACTDILQKNTDWTNRN 480
Query: 506 G 508
G
Sbjct: 481 G 481
Score = 35.1 bits (77), Expect = 0.23
Identities = 23/75 (30%), Positives = 39/75 (52%), Gaps = 6/75 (8%)
Frame = +3
Query: 33 SEIQELSVVGKGAFGVVWK--GVWRNRFVAVKHINSEAEKREFAI----EVRQLSRVCHP 194
+E +EL ++GKG +G V+K ++ A+K I + + + EV+ L+ + HP
Sbjct: 165 NEFEELVILGKGGYGRVYKVRNKLDGQYYAIKKILIKGATKTVCMKVLREVKVLAGLQHP 224
Query: 195 NIVRLYGACTRGAHV 239
NIV + A HV
Sbjct: 225 NIVGYHTAWIEHVHV 239
Score = 31.1 bits (67), Expect = 3.8
Identities = 12/28 (42%), Positives = 19/28 (67%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEV 600
+ +PE EGS Y K D++S G++L E+
Sbjct: 496 YASPEQLEGSEYDAKSDMYSLGVVLLEL 523
>AF167472-1|AAF13156.1| 551|Homo sapiens double stranded RNA
activated protein kinase protein.
Length = 551
Score = 48.0 bits (109), Expect = 3e-05
Identities = 34/85 (40%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Frame = +2
Query: 266 GSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQR 445
G+L + R K A+ Q +GV Y+HS K LIHRDLKP N+ LV Q
Sbjct: 372 GTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKK---LIHRDLKPSNIFLVDTKQ- 427
Query: 446 LKICDFG--TAADKATYMTNNKGVL 514
+KI DFG T+ T +KG L
Sbjct: 428 VKIGDFGLVTSLKNDGKRTRSKGTL 452
Score = 36.3 bits (80), Expect = 0.10
Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Frame = +3
Query: 36 EIQELSVVGKGAFGVVWKGVWR--NRFVAVKHINSEAEKREFAIEVRQLSRVCHPNIVRL 209
+ +E+ ++G G FG V+K R + +K + EK E EV+ L+++ H NIV
Sbjct: 266 DFKEIELIGSGGFGQVFKAKHRIDGKTYVIKRVKYNNEKAE--REVKALAKLDHVNIVH- 322
Query: 210 YGACTRG 230
Y C G
Sbjct: 323 YNGCWDG 329
>AF147094-1|AAF66736.1| 629|Homo sapiens heme-regulated initiation
factor 2 alpha kinase protein.
Length = 629
Score = 48.0 bits (109), Expect = 3e-05
Identities = 27/61 (44%), Positives = 36/61 (59%), Gaps = 4/61 (6%)
Frame = +2
Query: 338 RQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTAA----DKATYMTNNK 505
++ EGV Y+H+M ++HRDLKP N+ L G Q++KI DFG A K T TN
Sbjct: 423 QELVEGVFYIHNMG---IVHRDLKPRNIFLHGPDQQVKIGDFGLACTDILQKNTDWTNRN 479
Query: 506 G 508
G
Sbjct: 480 G 480
Score = 38.7 bits (86), Expect = 0.019
Identities = 26/101 (25%), Positives = 49/101 (48%), Gaps = 6/101 (5%)
Frame = +3
Query: 33 SEIQELSVVGKGAFGVVWK--GVWRNRFVAVKHINSEAEKREFAI----EVRQLSRVCHP 194
+E +EL+++GKG +G V+K ++ A+K I + + + EV+ L+ + HP
Sbjct: 165 NEFEELAILGKGGYGRVYKVRNKLDGQYYAIKKILIKGATKPVCMKVLREVKVLAGLQHP 224
Query: 195 NIVRLYGACTRGAHVCLVMEMQKVALSIMYYTTDPNPNTQQ 317
NIV + A HV + + L + +D + +Q
Sbjct: 225 NIVGYHTAWIEHVHVIQPRDRAAIELPSLEVLSDQEEDREQ 265
Score = 31.1 bits (67), Expect = 3.8
Identities = 12/28 (42%), Positives = 19/28 (67%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEV 600
+ +PE EGS Y K D++S G++L E+
Sbjct: 495 YASPEQLEGSEYDAKSDMYSLGVVLLEL 522
>AF100784-1|AAP97223.1| 630|Homo sapiens hemin-sensitive
inititation factor 2a kinase protein.
Length = 630
Score = 48.0 bits (109), Expect = 3e-05
Identities = 27/61 (44%), Positives = 36/61 (59%), Gaps = 4/61 (6%)
Frame = +2
Query: 338 RQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTAA----DKATYMTNNK 505
++ EGV Y+H+M ++HRDLKP N+ L G Q++KI DFG A K T TN
Sbjct: 424 QELVEGVFYIHNMG---IVHRDLKPRNIFLHGPDQQVKIGDFGLACTDILQKNTDWTNRN 480
Query: 506 G 508
G
Sbjct: 481 G 481
Score = 36.3 bits (80), Expect = 0.10
Identities = 23/75 (30%), Positives = 40/75 (53%), Gaps = 6/75 (8%)
Frame = +3
Query: 33 SEIQELSVVGKGAFGVVWK--GVWRNRFVAVKHINSEAEKREFAI----EVRQLSRVCHP 194
+E +EL+++GKG +G V+K ++ A+K I + + + EV+ L+ + HP
Sbjct: 165 NEFEELAILGKGGYGRVYKVRNKLDGQYYAIKKILIKGATKTVCMKVLREVKVLAGLQHP 224
Query: 195 NIVRLYGACTRGAHV 239
NIV + A HV
Sbjct: 225 NIVGYHTAWIEHVHV 239
Score = 31.1 bits (67), Expect = 3.8
Identities = 12/28 (42%), Positives = 19/28 (67%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEV 600
+ +PE EGS Y K D++S G++L E+
Sbjct: 496 YASPEQLEGSEYDAKSDMYSLGVVLLEL 523
>AF061944-1|AAF31483.1| 670|Homo sapiens kinase deficient protein
KDP protein.
Length = 670
Score = 48.0 bits (109), Expect = 3e-05
Identities = 23/51 (45%), Positives = 31/51 (60%)
Frame = +2
Query: 329 SWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTAADK 481
SW RQ +G+ +LH+ P P+IHRDLK N+ + G +KI D G A K
Sbjct: 326 SWCRQILKGLQFLHTRTP-PIIHRDLKCDNIFITGPTGSVKIGDLGLATLK 375
Score = 33.5 bits (73), Expect = 0.71
Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 6/58 (10%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKHIN------SEAEKREFAIEVRQLSRVCHPNIVRLY 212
+G+G+F V+KG+ V V +++E++ F E L + HPNIVR Y
Sbjct: 227 IGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFY 284
>AC007899-1|AAY24317.1| 551|Homo sapiens unknown protein.
Length = 551
Score = 48.0 bits (109), Expect = 3e-05
Identities = 34/85 (40%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Frame = +2
Query: 266 GSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQR 445
G+L + R K A+ Q +GV Y+HS K LIHRDLKP N+ LV Q
Sbjct: 372 GTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKK---LIHRDLKPSNIFLVDTKQ- 427
Query: 446 LKICDFG--TAADKATYMTNNKGVL 514
+KI DFG T+ T +KG L
Sbjct: 428 VKIGDFGLVTSLKNDGKRTRSKGTL 452
Score = 36.3 bits (80), Expect = 0.10
Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Frame = +3
Query: 36 EIQELSVVGKGAFGVVWKGVWR--NRFVAVKHINSEAEKREFAIEVRQLSRVCHPNIVRL 209
+ +E+ ++G G FG V+K R + +K + EK E EV+ L+++ H NIV
Sbjct: 266 DFKEIELIGSGGFGQVFKAKHRIDGKTYVIKRVKYNNEKAE--REVKALAKLDHVNIVH- 322
Query: 210 YGACTRG 230
Y C G
Sbjct: 323 YNGCWDG 329
>AC006344-3|AAD43193.1| 651|Homo sapiens WUGSC:H_DJ0726N20.3
protein.
Length = 651
Score = 48.0 bits (109), Expect = 3e-05
Identities = 32/77 (41%), Positives = 44/77 (57%)
Frame = +2
Query: 260 EGGSLYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGG 439
EG SLY+ LH + K+ + ARQ A+G+ YLH+ K +IHRDLK N+ L
Sbjct: 418 EGSSLYHHLHII-ETKFEMIKLIDIARQTAQGMDYLHA---KSIIHRDLKSNNIFL-HED 472
Query: 440 QRLKICDFGTAADKATY 490
+KI DFG A K+ +
Sbjct: 473 LTVKIGDFGLATVKSRW 489
Score = 37.1 bits (82), Expect = 0.057
Identities = 26/73 (35%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
Frame = +3
Query: 21 EIDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEA----EKREFAIEVRQLSRVC 188
EI +I +G G+FG V+KG W VAVK +N A + + F EV L +
Sbjct: 336 EIPDGQITVGQRIGSGSFGTVYKGKWHGD-VAVKMLNVTAPTPQQLQAFKNEVGVLRKTR 394
Query: 189 HPNIVRLYGACTR 227
H NI+ G T+
Sbjct: 395 HVNILLFMGYSTK 407
Score = 34.7 bits (76), Expect = 0.31
Identities = 14/38 (36%), Positives = 28/38 (73%), Gaps = 3/38 (7%)
Frame = +1
Query: 517 WMAPEVF---EGSTYTEKCDVFSWGIILWEVLSRRKPF 621
WMAPEV + + Y+ + DV+++GI+L+E+++ + P+
Sbjct: 504 WMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPY 541
>AC005995-1|AAS00388.1| 386|Homo sapiens unknown protein.
Length = 386
Score = 48.0 bits (109), Expect = 3e-05
Identities = 27/61 (44%), Positives = 36/61 (59%), Gaps = 4/61 (6%)
Frame = +2
Query: 338 RQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTAA----DKATYMTNNK 505
++ EGV Y+H+M ++HRDLKP N+ L G Q++KI DFG A K T TN
Sbjct: 180 QELVEGVFYIHNMG---IVHRDLKPRNIFLHGPDQQVKIGDFGLACTDILQKNTDWTNRN 236
Query: 506 G 508
G
Sbjct: 237 G 237
Score = 31.1 bits (67), Expect = 3.8
Identities = 12/28 (42%), Positives = 19/28 (67%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEV 600
+ +PE EGS Y K D++S G++L E+
Sbjct: 252 YASPEQLEGSEYDAKSDMYSLGVVLLEL 279
>AB209642-1|BAD92879.1| 949|Homo sapiens Proto-oncogene
tyrosine-protein kinase ABL1 variant protein.
Length = 949
Score = 48.0 bits (109), Expect = 3e-05
Identities = 25/68 (36%), Positives = 38/68 (55%), Gaps = 3/68 (4%)
Frame = +3
Query: 60 GKGAFGVVWKGVWR--NRFVAVKHINSEA-EKREFAIEVRQLSRVCHPNIVRLYGACTRG 230
G G +G V++GVW+ + VAVK + + E EF E + + HPN+V+L G CTR
Sbjct: 68 GGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTRE 127
Query: 231 AHVCLVME 254
++ E
Sbjct: 128 PPFYIITE 135
Score = 33.1 bits (72), Expect = 0.93
Identities = 11/28 (39%), Positives = 20/28 (71%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEV 600
W APE + ++ K DV+++G++LWE+
Sbjct: 224 WTAPESLAYNKFSIKSDVWAFGVLLWEI 251
>AB051547-1|BAB21851.2| 2219|Homo sapiens KIAA1760 protein protein.
Length = 2219
Score = 48.0 bits (109), Expect = 3e-05
Identities = 23/51 (45%), Positives = 31/51 (60%)
Frame = +2
Query: 329 SWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTAADK 481
SW RQ +G+ +LH+ P P+IHRDLK N+ + G +KI D G A K
Sbjct: 295 SWCRQILKGLLFLHTRTP-PIIHRDLKCDNIFITGPTGSVKIGDLGLATLK 344
Score = 33.1 bits (72), Expect = 0.93
Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 6/58 (10%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKHIN------SEAEKREFAIEVRQLSRVCHPNIVRLY 212
+G+G+F V+KG+ +V V ++ E++ F E L + HPNIVR Y
Sbjct: 196 LGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFKEEAEMLKGLQHPNIVRFY 253
>AB044546-1|BAB18648.1| 779|Homo sapiens mitogen-activated protein
kinase kinase kinase protein.
Length = 779
Score = 48.0 bits (109), Expect = 3e-05
Identities = 23/51 (45%), Positives = 31/51 (60%)
Frame = +2
Query: 329 SWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTAADK 481
SW RQ +G+ +LH+ P P+IHRDLK N+ + G +KI D G A K
Sbjct: 286 SWCRQILKGLLFLHTRTP-PIIHRDLKCDNIFITGPTGSVKIGDLGLATLK 335
Score = 33.1 bits (72), Expect = 0.93
Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 6/58 (10%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKHIN------SEAEKREFAIEVRQLSRVCHPNIVRLY 212
+G+G+F V+KG+ +V V ++ E++ F E L + HPNIVR Y
Sbjct: 187 LGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFKEEAEMLKGLQHPNIVRFY 244
>AB037790-1|BAA92607.1| 653|Homo sapiens KIAA1369 protein protein.
Length = 653
Score = 48.0 bits (109), Expect = 3e-05
Identities = 27/61 (44%), Positives = 36/61 (59%), Gaps = 4/61 (6%)
Frame = +2
Query: 338 RQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTAA----DKATYMTNNK 505
++ EGV Y+H+M ++HRDLKP N+ L G Q++KI DFG A K T TN
Sbjct: 447 QELVEGVFYIHNMG---IVHRDLKPRNIFLHGPDQQVKIGDFGLACTDILQKNTDWTNRN 503
Query: 506 G 508
G
Sbjct: 504 G 504
Score = 36.3 bits (80), Expect = 0.10
Identities = 23/75 (30%), Positives = 40/75 (53%), Gaps = 6/75 (8%)
Frame = +3
Query: 33 SEIQELSVVGKGAFGVVWK--GVWRNRFVAVKHINSEAEKREFAI----EVRQLSRVCHP 194
+E +EL+++GKG +G V+K ++ A+K I + + + EV+ L+ + HP
Sbjct: 188 NEFEELAILGKGGYGRVYKVRNKLDGQYYAIKKILIKGATKTVCMKVLREVKVLAGLQHP 247
Query: 195 NIVRLYGACTRGAHV 239
NIV + A HV
Sbjct: 248 NIVGYHTAWIEHVHV 262
Score = 31.1 bits (67), Expect = 3.8
Identities = 12/28 (42%), Positives = 19/28 (67%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEV 600
+ +PE EGS Y K D++S G++L E+
Sbjct: 519 YASPEQLEGSEYDAKSDMYSLGVVLLEL 546
>AB002342-1|BAA20802.2| 2066|Homo sapiens KIAA0344 protein.
Length = 2066
Score = 48.0 bits (109), Expect = 3e-05
Identities = 23/51 (45%), Positives = 31/51 (60%)
Frame = +2
Query: 329 SWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTAADK 481
SW RQ +G+ +LH+ P P+IHRDLK N+ + G +KI D G A K
Sbjct: 258 SWCRQILKGLQFLHTRTP-PIIHRDLKCDNIFITGPTGSVKIGDLGLATLK 307
Score = 33.5 bits (73), Expect = 0.71
Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 6/58 (10%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKHIN------SEAEKREFAIEVRQLSRVCHPNIVRLY 212
+G+G+F V+KG+ V V +++E++ F E L + HPNIVR Y
Sbjct: 159 IGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFY 216
>Z84469-2|CAI42732.1| 1790|Homo sapiens WNK lysine deficient protein
kinase 3 protein.
Length = 1790
Score = 47.6 bits (108), Expect = 4e-05
Identities = 22/48 (45%), Positives = 30/48 (62%)
Frame = +2
Query: 329 SWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTA 472
SW RQ +G+ +LH+ P P+IHRDLK N+ + G +KI D G A
Sbjct: 252 SWCRQILKGLQFLHTRTP-PIIHRDLKCDNIFITGPTGSVKIGDLGLA 298
Score = 35.9 bits (79), Expect = 0.13
Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 6/58 (10%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKHIN------SEAEKREFAIEVRQLSRVCHPNIVRLY 212
+G+GAF V+KG+ +V V ++AE++ F E L + HPNIVR Y
Sbjct: 153 LGRGAFKTVYKGLDTETWVEVAWCELQDRKLTKAEQQRFKEEAEMLKGLQHPNIVRFY 210
>Z84469-1|CAI42733.1| 1743|Homo sapiens WNK lysine deficient protein
kinase 3 protein.
Length = 1743
Score = 47.6 bits (108), Expect = 4e-05
Identities = 22/48 (45%), Positives = 30/48 (62%)
Frame = +2
Query: 329 SWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTA 472
SW RQ +G+ +LH+ P P+IHRDLK N+ + G +KI D G A
Sbjct: 252 SWCRQILKGLQFLHTRTP-PIIHRDLKCDNIFITGPTGSVKIGDLGLA 298
Score = 35.9 bits (79), Expect = 0.13
Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 6/58 (10%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKHIN------SEAEKREFAIEVRQLSRVCHPNIVRLY 212
+G+GAF V+KG+ +V V ++AE++ F E L + HPNIVR Y
Sbjct: 153 LGRGAFKTVYKGLDTETWVEVAWCELQDRKLTKAEQQRFKEEAEMLKGLQHPNIVRFY 210
>U63333-1|AAB05809.1| 433|Homo sapiens serine/threonine protein
kinase protein.
Length = 433
Score = 47.6 bits (108), Expect = 4e-05
Identities = 25/67 (37%), Positives = 39/67 (58%)
Frame = +2
Query: 272 LYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLK 451
+ +L + P+ ++ A + Q +G+ YLHS + ++H+D+KP NLLL GG LK
Sbjct: 136 MQEMLDSVPEKRFPVCQAHGYFCQLIDGLEYLHS---QGIVHKDIKPGNLLLTTGG-TLK 191
Query: 452 ICDFGTA 472
I D G A
Sbjct: 192 ISDLGVA 198
>U07695-1|AAA20598.1| 987|Homo sapiens tyrosine kinase protein.
Length = 987
Score = 47.6 bits (108), Expect = 4e-05
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVWR-----NRFVAVKHIN---SEAEKREFAIEV 167
F +EID S ++ V+G G FG V +G + VA+K + +E ++REF E
Sbjct: 606 FAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEA 665
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPNI+RL G T V ++ E +
Sbjct: 666 SIMGQFEHPNIIRLEGVVTNSMPVMILTEFME 697
Score = 36.3 bits (80), Expect = 0.10
Identities = 13/30 (43%), Positives = 19/30 (63%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE +T D +S+GI++WEV+S
Sbjct: 786 WTAPEAIAFRKFTSASDAWSYGIVMWEVMS 815
>D88435-1|BAA22623.1| 1311|Homo sapiens HsGAK protein.
Length = 1311
Score = 47.6 bits (108), Expect = 4e-05
Identities = 24/50 (48%), Positives = 31/50 (62%)
Frame = +2
Query: 341 QCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTAADKATY 490
Q V ++H KP P+IHRDLK NLLL G +K+CDFG+A + Y
Sbjct: 154 QTCRAVQHMHRQKP-PIIHRDLKVENLLLSNQG-TIKLCDFGSATTISHY 201
>BC085005-1|AAH85005.1| 1232|Homo sapiens GAK protein protein.
Length = 1232
Score = 47.6 bits (108), Expect = 4e-05
Identities = 24/50 (48%), Positives = 31/50 (62%)
Frame = +2
Query: 341 QCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTAADKATY 490
Q V ++H KP P+IHRDLK NLLL G +K+CDFG+A + Y
Sbjct: 75 QTCRAVQHMHRQKP-PIIHRDLKVENLLLSNQG-TIKLCDFGSATTISHY 122
>BC052804-1|AAH52804.1| 987|Homo sapiens EPH receptor B4 protein.
Length = 987
Score = 47.6 bits (108), Expect = 4e-05
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVWR-----NRFVAVKHIN---SEAEKREFAIEV 167
F +EID S ++ V+G G FG V +G + VA+K + +E ++REF E
Sbjct: 606 FAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEA 665
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPNI+RL G T V ++ E +
Sbjct: 666 SIMGQFEHPNIIRLEGVVTNSMPVMILTEFME 697
Score = 36.3 bits (80), Expect = 0.10
Identities = 13/30 (43%), Positives = 19/30 (63%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE +T D +S+GI++WEV+S
Sbjct: 786 WTAPEAIAFRKFTSASDAWSYGIVMWEVMS 815
>BC019334-1|AAH19334.1| 433|Homo sapiens serine/threonine kinase 11
protein.
Length = 433
Score = 47.6 bits (108), Expect = 4e-05
Identities = 25/67 (37%), Positives = 39/67 (58%)
Frame = +2
Query: 272 LYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLK 451
+ +L + P+ ++ A + Q +G+ YLHS + ++H+D+KP NLLL GG LK
Sbjct: 136 MQEMLDSVPEKRFPVCQAHGYFCQLIDGLEYLHS---QGIVHKDIKPGNLLLTTGG-TLK 191
Query: 452 ICDFGTA 472
I D G A
Sbjct: 192 ISDLGVA 198
>BC007981-1|AAH07981.1| 433|Homo sapiens serine/threonine kinase 11
protein.
Length = 433
Score = 47.6 bits (108), Expect = 4e-05
Identities = 25/67 (37%), Positives = 39/67 (58%)
Frame = +2
Query: 272 LYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLK 451
+ +L + P+ ++ A + Q +G+ YLHS + ++H+D+KP NLLL GG LK
Sbjct: 136 MQEMLDSVPEKRFPVCQAHGYFCQLIDGLEYLHS---QGIVHKDIKPGNLLLTTGG-TLK 191
Query: 452 ICDFGTA 472
I D G A
Sbjct: 192 ISDLGVA 198
>BC004264-1|AAH04264.1| 845|Homo sapiens EPHB4 protein protein.
Length = 845
Score = 47.6 bits (108), Expect = 4e-05
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVWR-----NRFVAVKHIN---SEAEKREFAIEV 167
F +EID S ++ V+G G FG V +G + VA+K + +E ++REF E
Sbjct: 464 FAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEA 523
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPNI+RL G T V ++ E +
Sbjct: 524 SIMGQFEHPNIIRLEGVVTNSMPVMILTEFME 555
Score = 36.3 bits (80), Expect = 0.10
Identities = 13/30 (43%), Positives = 19/30 (63%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE +T D +S+GI++WEV+S
Sbjct: 644 WTAPEAIAFRKFTSASDAWSYGIVMWEVMS 673
>AY352048-1|AAR89465.1| 1800|Homo sapiens putative protein kinase
WNK3 protein.
Length = 1800
Score = 47.6 bits (108), Expect = 4e-05
Identities = 22/48 (45%), Positives = 30/48 (62%)
Frame = +2
Query: 329 SWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTA 472
SW RQ +G+ +LH+ P P+IHRDLK N+ + G +KI D G A
Sbjct: 252 SWCRQILKGLQFLHTRTP-PIIHRDLKCDNIFITGPTGSVKIGDLGLA 298
Score = 35.9 bits (79), Expect = 0.13
Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 6/58 (10%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKHIN------SEAEKREFAIEVRQLSRVCHPNIVRLY 212
+G+GAF V+KG+ +V V ++AE++ F E L + HPNIVR Y
Sbjct: 153 LGRGAFKTVYKGLDTETWVEVAWCELQDRKLTKAEQQRFKEEAEMLKGLQHPNIVRFY 210
>AY082340-1|AAL99253.1| 1800|Homo sapiens putative protein kinase
WNK3 protein.
Length = 1800
Score = 47.6 bits (108), Expect = 4e-05
Identities = 22/48 (45%), Positives = 30/48 (62%)
Frame = +2
Query: 329 SWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTA 472
SW RQ +G+ +LH+ P P+IHRDLK N+ + G +KI D G A
Sbjct: 252 SWCRQILKGLQFLHTRTP-PIIHRDLKCDNIFITGPTGSVKIGDLGLA 298
Score = 35.9 bits (79), Expect = 0.13
Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 6/58 (10%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKHIN------SEAEKREFAIEVRQLSRVCHPNIVRLY 212
+G+GAF V+KG+ +V V ++AE++ F E L + HPNIVR Y
Sbjct: 153 LGRGAFKTVYKGLDTETWVEVAWCELQDRKLTKAEQQRFKEEAEMLKGLQHPNIVRFY 210
>AY056048-1|AAL14195.1| 935|Homo sapiens receptor protein tyrosine
kinase variant EphB4v1 protein.
Length = 935
Score = 47.6 bits (108), Expect = 4e-05
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVWR-----NRFVAVKHIN---SEAEKREFAIEV 167
F +EID S ++ V+G G FG V +G + VA+K + +E ++REF E
Sbjct: 606 FAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEA 665
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPNI+RL G T V ++ E +
Sbjct: 666 SIMGQFEHPNIIRLEGVVTNSMPVMILTEFME 697
Score = 36.3 bits (80), Expect = 0.10
Identities = 13/30 (43%), Positives = 19/30 (63%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE +T D +S+GI++WEV+S
Sbjct: 786 WTAPEAIAFRKFTSASDAWSYGIVMWEVMS 815
>AY056047-1|AAL14194.1| 987|Homo sapiens receptor protein tyrosine
kinase EphB4 protein.
Length = 987
Score = 47.6 bits (108), Expect = 4e-05
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVWR-----NRFVAVKHIN---SEAEKREFAIEV 167
F +EID S ++ V+G G FG V +G + VA+K + +E ++REF E
Sbjct: 606 FAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEA 665
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPNI+RL G T V ++ E +
Sbjct: 666 SIMGQFEHPNIIRLEGVVTNSMPVMILTEFME 697
Score = 36.3 bits (80), Expect = 0.10
Identities = 13/30 (43%), Positives = 19/30 (63%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE +T D +S+GI++WEV+S
Sbjct: 786 WTAPEAIAFRKFTSASDAWSYGIVMWEVMS 815
>AL591766-2|CAI40707.1| 1790|Homo sapiens WNK lysine deficient
protein kinase 3 protein.
Length = 1790
Score = 47.6 bits (108), Expect = 4e-05
Identities = 22/48 (45%), Positives = 30/48 (62%)
Frame = +2
Query: 329 SWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTA 472
SW RQ +G+ +LH+ P P+IHRDLK N+ + G +KI D G A
Sbjct: 252 SWCRQILKGLQFLHTRTP-PIIHRDLKCDNIFITGPTGSVKIGDLGLA 298
Score = 35.9 bits (79), Expect = 0.13
Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 6/58 (10%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKHIN------SEAEKREFAIEVRQLSRVCHPNIVRLY 212
+G+GAF V+KG+ +V V ++AE++ F E L + HPNIVR Y
Sbjct: 153 LGRGAFKTVYKGLDTETWVEVAWCELQDRKLTKAEQQRFKEEAEMLKGLQHPNIVRFY 210
>AL591766-1|CAI40708.1| 1743|Homo sapiens WNK lysine deficient
protein kinase 3 protein.
Length = 1743
Score = 47.6 bits (108), Expect = 4e-05
Identities = 22/48 (45%), Positives = 30/48 (62%)
Frame = +2
Query: 329 SWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTA 472
SW RQ +G+ +LH+ P P+IHRDLK N+ + G +KI D G A
Sbjct: 252 SWCRQILKGLQFLHTRTP-PIIHRDLKCDNIFITGPTGSVKIGDLGLA 298
Score = 35.9 bits (79), Expect = 0.13
Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 6/58 (10%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKHIN------SEAEKREFAIEVRQLSRVCHPNIVRLY 212
+G+GAF V+KG+ +V V ++AE++ F E L + HPNIVR Y
Sbjct: 153 LGRGAFKTVYKGLDTETWVEVAWCELQDRKLTKAEQQRFKEEAEMLKGLQHPNIVRFY 210
>AL049793-2|CAI43128.1| 1790|Homo sapiens WNK lysine deficient
protein kinase 3 protein.
Length = 1790
Score = 47.6 bits (108), Expect = 4e-05
Identities = 22/48 (45%), Positives = 30/48 (62%)
Frame = +2
Query: 329 SWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTA 472
SW RQ +G+ +LH+ P P+IHRDLK N+ + G +KI D G A
Sbjct: 252 SWCRQILKGLQFLHTRTP-PIIHRDLKCDNIFITGPTGSVKIGDLGLA 298
Score = 35.9 bits (79), Expect = 0.13
Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 6/58 (10%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKHIN------SEAEKREFAIEVRQLSRVCHPNIVRLY 212
+G+GAF V+KG+ +V V ++AE++ F E L + HPNIVR Y
Sbjct: 153 LGRGAFKTVYKGLDTETWVEVAWCELQDRKLTKAEQQRFKEEAEMLKGLQHPNIVRFY 210
>AL049793-1|CAI43129.1| 1743|Homo sapiens WNK lysine deficient
protein kinase 3 protein.
Length = 1743
Score = 47.6 bits (108), Expect = 4e-05
Identities = 22/48 (45%), Positives = 30/48 (62%)
Frame = +2
Query: 329 SWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTA 472
SW RQ +G+ +LH+ P P+IHRDLK N+ + G +KI D G A
Sbjct: 252 SWCRQILKGLQFLHTRTP-PIIHRDLKCDNIFITGPTGSVKIGDLGLA 298
Score = 35.9 bits (79), Expect = 0.13
Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 6/58 (10%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKHIN------SEAEKREFAIEVRQLSRVCHPNIVRLY 212
+G+GAF V+KG+ +V V ++AE++ F E L + HPNIVR Y
Sbjct: 153 LGRGAFKTVYKGLDTETWVEVAWCELQDRKLTKAEQQRFKEEAEMLKGLQHPNIVRFY 210
>AJ409088-1|CAC32455.2| 1743|Homo sapiens protein kinase WNK3
protein.
Length = 1743
Score = 47.6 bits (108), Expect = 4e-05
Identities = 22/48 (45%), Positives = 30/48 (62%)
Frame = +2
Query: 329 SWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTA 472
SW RQ +G+ +LH+ P P+IHRDLK N+ + G +KI D G A
Sbjct: 252 SWCRQILKGLQFLHTRTP-PIIHRDLKCDNIFITGPTGSVKIGDLGLA 298
Score = 35.9 bits (79), Expect = 0.13
Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 6/58 (10%)
Frame = +3
Query: 57 VGKGAFGVVWKGVWRNRFVAVKHIN------SEAEKREFAIEVRQLSRVCHPNIVRLY 212
+G+GAF V+KG+ +V V ++AE++ F E L + HPNIVR Y
Sbjct: 153 LGRGAFKTVYKGLDTETWVEVAWCELQDRKLTKAEQQRFKEEAEMLKGLQHPNIVRFY 210
>AF312032-8|AAK21010.1| 987|Homo sapiens ephrin type-B receptor 4
precursor protein.
Length = 987
Score = 47.6 bits (108), Expect = 4e-05
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVWR-----NRFVAVKHIN---SEAEKREFAIEV 167
F +EID S ++ V+G G FG V +G + VA+K + +E ++REF E
Sbjct: 606 FAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEA 665
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPNI+RL G T V ++ E +
Sbjct: 666 SIMGQFEHPNIIRLEGVVTNSMPVMILTEFME 697
Score = 36.3 bits (80), Expect = 0.10
Identities = 13/30 (43%), Positives = 19/30 (63%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE +T D +S+GI++WEV+S
Sbjct: 786 WTAPEAIAFRKFTSASDAWSYGIVMWEVMS 815
>AF217978-1|AAG17221.1| 433|Homo sapiens unknown protein.
Length = 433
Score = 47.6 bits (108), Expect = 4e-05
Identities = 25/67 (37%), Positives = 39/67 (58%)
Frame = +2
Query: 272 LYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLK 451
+ +L + P+ ++ A + Q +G+ YLHS + ++H+D+KP NLLL GG LK
Sbjct: 136 MQEMLDSVPEKRFPVCQAHGYFCQLIDGLEYLHS---QGIVHKDIKPGNLLLTTGG-TLK 191
Query: 452 ICDFGTA 472
I D G A
Sbjct: 192 ISDLGVA 198
>AF055327-1|AAC15742.1| 433|Homo sapiens Peutz-Jeghers syndrome
protein protein.
Length = 433
Score = 47.6 bits (108), Expect = 4e-05
Identities = 25/67 (37%), Positives = 39/67 (58%)
Frame = +2
Query: 272 LYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLK 451
+ +L + P+ ++ A + Q +G+ YLHS + ++H+D+KP NLLL GG LK
Sbjct: 136 MQEMLDSVPEKRFPVCQAHGYFCQLIDGLEYLHS---QGIVHKDIKPGNLLLTTGG-TLK 191
Query: 452 ICDFGTA 472
I D G A
Sbjct: 192 ISDLGVA 198
>AF035625-1|AAC39527.1| 433|Homo sapiens serine threonine kinase 11
protein.
Length = 433
Score = 47.6 bits (108), Expect = 4e-05
Identities = 25/67 (37%), Positives = 39/67 (58%)
Frame = +2
Query: 272 LYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLK 451
+ +L + P+ ++ A + Q +G+ YLHS + ++H+D+KP NLLL GG LK
Sbjct: 136 MQEMLDSVPEKRFPVCQAHGYFCQLIDGLEYLHS---QGIVHKDIKPGNLLLTTGG-TLK 191
Query: 452 ICDFGTA 472
I D G A
Sbjct: 192 ISDLGVA 198
>AF032986-1|AAB97833.1| 433|Homo sapiens serine threonine kinase 11
protein.
Length = 433
Score = 47.6 bits (108), Expect = 4e-05
Identities = 25/67 (37%), Positives = 39/67 (58%)
Frame = +2
Query: 272 LYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLK 451
+ +L + P+ ++ A + Q +G+ YLHS + ++H+D+KP NLLL GG LK
Sbjct: 136 MQEMLDSVPEKRFPVCQAHGYFCQLIDGLEYLHS---QGIVHKDIKPGNLLLTTGG-TLK 191
Query: 452 ICDFGTA 472
I D G A
Sbjct: 192 ISDLGVA 198
>AB209644-1|BAD92881.1| 986|Homo sapiens ephrin receptor EphB4
precursor variant protein.
Length = 986
Score = 47.6 bits (108), Expect = 4e-05
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 8/92 (8%)
Frame = +3
Query: 12 FVEEIDYSEIQELSVVGKGAFGVVWKGVWR-----NRFVAVKHIN---SEAEKREFAIEV 167
F +EID S ++ V+G G FG V +G + VA+K + +E ++REF E
Sbjct: 605 FAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEA 664
Query: 168 RQLSRVCHPNIVRLYGACTRGAHVCLVMEMQK 263
+ + HPNI+RL G T V ++ E +
Sbjct: 665 SIMGQFEHPNIIRLEGVVTNSMPVMILTEFME 696
Score = 36.3 bits (80), Expect = 0.10
Identities = 13/30 (43%), Positives = 19/30 (63%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS 606
W APE +T D +S+GI++WEV+S
Sbjct: 785 WTAPEAIAFRKFTSASDAWSYGIVMWEVMS 814
>AB209553-1|BAD92790.1| 337|Homo sapiens serine/threonine protein
kinase 11 variant protein.
Length = 337
Score = 47.6 bits (108), Expect = 4e-05
Identities = 25/67 (37%), Positives = 39/67 (58%)
Frame = +2
Query: 272 LYNVLHNRPKPKYTAAHAMSWARQCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLK 451
+ +L + P+ ++ A + Q +G+ YLHS + ++H+D+KP NLLL GG LK
Sbjct: 166 MQEMLDSVPEKRFPVCQAHGYFCQLIDGLEYLHS---QGIVHKDIKPGNLLLTTGG-TLK 221
Query: 452 ICDFGTA 472
I D G A
Sbjct: 222 ISDLGVA 228
>AB208854-1|BAD92091.1| 1196|Homo sapiens Cyclin G-associated kinase
variant protein.
Length = 1196
Score = 47.6 bits (108), Expect = 4e-05
Identities = 24/50 (48%), Positives = 31/50 (62%)
Frame = +2
Query: 341 QCAEGVAYLHSMKPKPLIHRDLKPPNLLLVGGGQRLKICDFGTAADKATY 490
Q V ++H KP P+IHRDLK NLLL G +K+CDFG+A + Y
Sbjct: 50 QTCRAVQHMHRQKP-PIIHRDLKVENLLLSNQG-TIKLCDFGSATTISHY 97
>X74765-1|CAB58562.1| 450|Homo sapiens protein tyrosine kinase
protein.
Length = 450
Score = 47.2 bits (107), Expect = 5e-05
Identities = 23/64 (35%), Positives = 38/64 (59%)
Frame = +3
Query: 24 IDYSEIQELSVVGKGAFGVVWKGVWRNRFVAVKHINSEAEKREFAIEVRQLSRVCHPNIV 203
++ E++ L +GKG FG V G +R VAVK I ++A + F E ++++ H N+V
Sbjct: 190 LNMKELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIKNDATAQAFLAEASVMTQLRHSNLV 249
Query: 204 RLYG 215
+L G
Sbjct: 250 QLLG 253
Score = 38.3 bits (85), Expect = 0.025
Identities = 17/38 (44%), Positives = 24/38 (63%), Gaps = 1/38 (2%)
Frame = +1
Query: 517 WMAPEVFEGSTYTEKCDVFSWGIILWEVLS-RRKPF*R 627
W APE ++ K DV+S+GI+LWE+ S R P+ R
Sbjct: 352 WTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPR 389
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 123,635,829
Number of Sequences: 237096
Number of extensions: 3120369
Number of successful extensions: 13099
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 8990
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 12336
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7671262118
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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