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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= NV060347.seq
         (634 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

CR541670-1|CAG46471.1|  283|Homo sapiens MTAP protein.                133   6e-31
L42634-1|AAR24607.2|  283|Homo sapiens methylthioadenosine phosp...   132   8e-31
L40432-1|AAG38871.1|  283|Homo sapiens methylthioadenosine phosp...   132   8e-31
AL359922-1|CAI16481.1|  283|Homo sapiens methylthioadenosine pho...   132   8e-31
U22233-1|AAA81646.1|  283|Homo sapiens methylthioadenosine phosp...   132   1e-30
BC026106-1|AAH26106.1|  283|Homo sapiens methylthioadenosine pho...   132   1e-30
BC012316-1|AAH12316.1|  242|Homo sapiens MTAP protein protein.        132   1e-30
AY712791-1|AAU04442.1|  283|Homo sapiens methylthioadenosine pho...   132   1e-30
CR541710-1|CAG46511.1|  283|Homo sapiens MTAP protein.                130   4e-30
AF109294-1|AAD19641.1|  143|Homo sapiens hypothetical methylthio...   126   7e-29
BC018625-1|AAH18625.1|  154|Homo sapiens MTAP protein protein.        124   3e-28
AK091741-1|BAC03737.1|  133|Homo sapiens protein ( Homo sapiens ...    32   1.5  
BC005029-1|AAH05029.1|  527|Homo sapiens LEPREL1 protein protein.      31   4.5  
AK001580-1|BAA91769.1|  527|Homo sapiens protein ( Homo sapiens ...    31   4.5  
AJ430351-1|CAD23039.2|  708|Homo sapiens leprecan-like 1 protein...    31   4.5  
DQ067453-1|AAZ23040.1| 1262|Homo sapiens diaphanous-1 protein.         30   5.9  
BC117257-1|AAI17258.1| 1262|Homo sapiens diaphanous homolog 1 (D...    30   5.9  
AY363395-1|AAQ63049.1| 1272|Homo sapiens diaphanous 1 protein.         30   5.9  
AK128837-1|BAC87637.1|  286|Homo sapiens protein ( Homo sapiens ...    30   5.9  
AK023345-1|BAB14533.1|  533|Homo sapiens protein ( Homo sapiens ...    30   5.9  
AF177663-1|AAD53166.1|  771|Homo sapiens GTPase-activating prote...    30   5.9  
AF117067-1|AAF43261.1|  974|Homo sapiens rho-type GTPase-activat...    30   5.9  
AB209482-1|BAD92719.1| 1299|Homo sapiens Diaphanous 1 variant pr...    30   5.9  

>CR541670-1|CAG46471.1|  283|Homo sapiens MTAP protein.
          Length = 283

 Score =  133 bits (321), Expect = 6e-31
 Identities = 70/129 (54%), Positives = 85/129 (65%), Gaps = 7/129 (5%)
 Frame = +1

Query: 256 GRPSDVLIEGQIKRVQCVLLARHGRKHQLQPSDVNYRANIWALKQVGCTHILATTATGSL 435
           G+PSD LI G+IK V CVLLARHGR+H + PS VNY+ANIWALK+ GCTH++ TTA GSL
Sbjct: 39  GKPSDALIMGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSL 98

Query: 436 VEEYRPGDLVILDDFIDRTWGRKCSF----TTTRRGV---RAACATCPCGRRIVGERAPH 594
            EE +PGD+VI+D FIDRT  R  SF     +  RGV     A   CP  R ++ E A  
Sbjct: 99  REEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKK 158

Query: 595 CXARAKSRG 621
              R  S+G
Sbjct: 159 LGLRCHSKG 167


>L42634-1|AAR24607.2|  283|Homo sapiens methylthioadenosine
           phosphorylase protein.
          Length = 283

 Score =  132 bits (320), Expect = 8e-31
 Identities = 70/129 (54%), Positives = 85/129 (65%), Gaps = 7/129 (5%)
 Frame = +1

Query: 256 GRPSDVLIEGQIKRVQCVLLARHGRKHQLQPSDVNYRANIWALKQVGCTHILATTATGSL 435
           G+PSD LI G+IK V CVLLARHGR+H + PS VNY+ANIWALK+ GCTH++ TTA GSL
Sbjct: 39  GKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSL 98

Query: 436 VEEYRPGDLVILDDFIDRTWGRKCSF----TTTRRGV---RAACATCPCGRRIVGERAPH 594
            EE +PGD+VI+D FIDRT  R  SF     +  RGV     A   CP  R ++ E A  
Sbjct: 99  REEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKK 158

Query: 595 CXARAKSRG 621
              R  S+G
Sbjct: 159 LGLRCHSKG 167


>L40432-1|AAG38871.1|  283|Homo sapiens methylthioadenosine
           phosphorylase protein.
          Length = 283

 Score =  132 bits (320), Expect = 8e-31
 Identities = 70/129 (54%), Positives = 85/129 (65%), Gaps = 7/129 (5%)
 Frame = +1

Query: 256 GRPSDVLIEGQIKRVQCVLLARHGRKHQLQPSDVNYRANIWALKQVGCTHILATTATGSL 435
           G+PSD LI G+IK V CVLLARHGR+H + PS VNY+ANIWALK+ GCTH++ TTA GSL
Sbjct: 39  GKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSL 98

Query: 436 VEEYRPGDLVILDDFIDRTWGRKCSF----TTTRRGV---RAACATCPCGRRIVGERAPH 594
            EE +PGD+VI+D FIDRT  R  SF     +  RGV     A   CP  R ++ E A  
Sbjct: 99  REEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKK 158

Query: 595 CXARAKSRG 621
              R  S+G
Sbjct: 159 LGLRCHSKG 167


>AL359922-1|CAI16481.1|  283|Homo sapiens methylthioadenosine
           phosphorylase protein.
          Length = 283

 Score =  132 bits (320), Expect = 8e-31
 Identities = 70/129 (54%), Positives = 85/129 (65%), Gaps = 7/129 (5%)
 Frame = +1

Query: 256 GRPSDVLIEGQIKRVQCVLLARHGRKHQLQPSDVNYRANIWALKQVGCTHILATTATGSL 435
           G+PSD LI G+IK V CVLLARHGR+H + PS VNY+ANIWALK+ GCTH++ TTA GSL
Sbjct: 39  GKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSL 98

Query: 436 VEEYRPGDLVILDDFIDRTWGRKCSF----TTTRRGV---RAACATCPCGRRIVGERAPH 594
            EE +PGD+VI+D FIDRT  R  SF     +  RGV     A   CP  R ++ E A  
Sbjct: 99  REEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKK 158

Query: 595 CXARAKSRG 621
              R  S+G
Sbjct: 159 LGLRCHSKG 167


>U22233-1|AAA81646.1|  283|Homo sapiens methylthioadenosine
           phosphorylase protein.
          Length = 283

 Score =  132 bits (319), Expect = 1e-30
 Identities = 69/129 (53%), Positives = 85/129 (65%), Gaps = 7/129 (5%)
 Frame = +1

Query: 256 GRPSDVLIEGQIKRVQCVLLARHGRKHQLQPSDVNYRANIWALKQVGCTHILATTATGSL 435
           G+PSD LI G+IK V C+LLARHGR+H + PS VNY+ANIWALK+ GCTH++ TTA GSL
Sbjct: 39  GKPSDALILGKIKNVDCILLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSL 98

Query: 436 VEEYRPGDLVILDDFIDRTWGRKCSF----TTTRRGV---RAACATCPCGRRIVGERAPH 594
            EE +PGD+VI+D FIDRT  R  SF     +  RGV     A   CP  R ++ E A  
Sbjct: 99  REEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKK 158

Query: 595 CXARAKSRG 621
              R  S+G
Sbjct: 159 LGLRCHSKG 167


>BC026106-1|AAH26106.1|  283|Homo sapiens methylthioadenosine
           phosphorylase protein.
          Length = 283

 Score =  132 bits (319), Expect = 1e-30
 Identities = 69/129 (53%), Positives = 85/129 (65%), Gaps = 7/129 (5%)
 Frame = +1

Query: 256 GRPSDVLIEGQIKRVQCVLLARHGRKHQLQPSDVNYRANIWALKQVGCTHILATTATGSL 435
           G+PSD LI G+IK V C+LLARHGR+H + PS VNY+ANIWALK+ GCTH++ TTA GSL
Sbjct: 39  GKPSDALILGKIKNVDCILLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSL 98

Query: 436 VEEYRPGDLVILDDFIDRTWGRKCSF----TTTRRGV---RAACATCPCGRRIVGERAPH 594
            EE +PGD+VI+D FIDRT  R  SF     +  RGV     A   CP  R ++ E A  
Sbjct: 99  REEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKK 158

Query: 595 CXARAKSRG 621
              R  S+G
Sbjct: 159 LGLRCHSKG 167


>BC012316-1|AAH12316.1|  242|Homo sapiens MTAP protein protein.
          Length = 242

 Score =  132 bits (319), Expect = 1e-30
 Identities = 69/129 (53%), Positives = 85/129 (65%), Gaps = 7/129 (5%)
 Frame = +1

Query: 256 GRPSDVLIEGQIKRVQCVLLARHGRKHQLQPSDVNYRANIWALKQVGCTHILATTATGSL 435
           G+PSD LI G+IK V C+LLARHGR+H + PS VNY+ANIWALK+ GCTH++ TTA GSL
Sbjct: 39  GKPSDALILGKIKNVDCILLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSL 98

Query: 436 VEEYRPGDLVILDDFIDRTWGRKCSF----TTTRRGV---RAACATCPCGRRIVGERAPH 594
            EE +PGD+VI+D FIDRT  R  SF     +  RGV     A   CP  R ++ E A  
Sbjct: 99  REEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKK 158

Query: 595 CXARAKSRG 621
              R  S+G
Sbjct: 159 LGLRCHSKG 167


>AY712791-1|AAU04442.1|  283|Homo sapiens methylthioadenosine
           phosphorylase protein.
          Length = 283

 Score =  132 bits (319), Expect = 1e-30
 Identities = 69/129 (53%), Positives = 85/129 (65%), Gaps = 7/129 (5%)
 Frame = +1

Query: 256 GRPSDVLIEGQIKRVQCVLLARHGRKHQLQPSDVNYRANIWALKQVGCTHILATTATGSL 435
           G+PSD LI G+IK V C+LLARHGR+H + PS VNY+ANIWALK+ GCTH++ TTA GSL
Sbjct: 39  GKPSDALILGKIKNVDCILLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSL 98

Query: 436 VEEYRPGDLVILDDFIDRTWGRKCSF----TTTRRGV---RAACATCPCGRRIVGERAPH 594
            EE +PGD+VI+D FIDRT  R  SF     +  RGV     A   CP  R ++ E A  
Sbjct: 99  REEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKK 158

Query: 595 CXARAKSRG 621
              R  S+G
Sbjct: 159 LGLRCHSKG 167


>CR541710-1|CAG46511.1|  283|Homo sapiens MTAP protein.
          Length = 283

 Score =  130 bits (314), Expect = 4e-30
 Identities = 69/129 (53%), Positives = 84/129 (65%), Gaps = 7/129 (5%)
 Frame = +1

Query: 256 GRPSDVLIEGQIKRVQCVLLARHGRKHQLQPSDVNYRANIWALKQVGCTHILATTATGSL 435
           G+PSD  I G+IK V CVLLARHGR+H + PS VNY+ANIWALK+ GCTH++ TTA GSL
Sbjct: 39  GKPSDASILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSL 98

Query: 436 VEEYRPGDLVILDDFIDRTWGRKCSF----TTTRRGV---RAACATCPCGRRIVGERAPH 594
            EE +PGD+VI+D FIDRT  R  SF     +  RGV     A   CP  R ++ E A  
Sbjct: 99  REEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKK 158

Query: 595 CXARAKSRG 621
              R  S+G
Sbjct: 159 LGLRCHSKG 167


>AF109294-1|AAD19641.1|  143|Homo sapiens hypothetical
           methylthioadenosine phosphorylase fusion protein
           protein.
          Length = 143

 Score =  126 bits (304), Expect = 7e-29
 Identities = 54/79 (68%), Positives = 66/79 (83%)
 Frame = +1

Query: 256 GRPSDVLIEGQIKRVQCVLLARHGRKHQLQPSDVNYRANIWALKQVGCTHILATTATGSL 435
           G+PSD LI G+IK V C+LLARHGR+H + PS VNY+ANIWALK+ GCTH++ TTA GSL
Sbjct: 39  GKPSDALILGKIKNVDCILLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSL 98

Query: 436 VEEYRPGDLVILDDFIDRT 492
            EE +PGD+VI+D FIDRT
Sbjct: 99  REEIQPGDIVIIDQFIDRT 117


>BC018625-1|AAH18625.1|  154|Homo sapiens MTAP protein protein.
          Length = 154

 Score =  124 bits (299), Expect = 3e-28
 Identities = 54/84 (64%), Positives = 66/84 (78%)
 Frame = +1

Query: 256 GRPSDVLIEGQIKRVQCVLLARHGRKHQLQPSDVNYRANIWALKQVGCTHILATTATGSL 435
           G+PSD LI G+IK V C+LLARHGR+H + PS VNY+ANIWALK+ GCTH++ TTA GSL
Sbjct: 39  GKPSDALILGKIKNVDCILLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSL 98

Query: 436 VEEYRPGDLVILDDFIDRTWGRKC 507
            EE +PGD+VI+D FID    R C
Sbjct: 99  REEIQPGDIVIIDQFIDSHVRRAC 122


>AK091741-1|BAC03737.1|  133|Homo sapiens protein ( Homo sapiens
           cDNA FLJ34422 fis, clone HHDPC2005185, moderately
           similar to STEROID RECEPTOR PROTEIN DG6. ).
          Length = 133

 Score = 32.3 bits (70), Expect = 1.5
 Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 1/46 (2%)
 Frame = +2

Query: 458 IWSYWTISLIGLGVGSAVLRQHGGGSARRVP-PAHAAGVLWESARR 592
           +W  W    +G G G+  L+       RR+P PAH A   WES RR
Sbjct: 71  LWVRWGRRGLGAGAGAG-LQLGAAAPVRRLPQPAHPARGQWESLRR 115


>BC005029-1|AAH05029.1|  527|Homo sapiens LEPREL1 protein protein.
          Length = 527

 Score = 30.7 bits (66), Expect = 4.5
 Identities = 15/35 (42%), Positives = 21/35 (60%)
 Frame = -1

Query: 265 RVSQRCDHLLFDLILEKRRIIEARTSDNSDLYFSY 161
           RV  +   L +D+  + RRI+E+    NS LYFSY
Sbjct: 341 RVPLKSARLFYDISEKARRIVESYFMLNSTLYFSY 375


>AK001580-1|BAA91769.1|  527|Homo sapiens protein ( Homo sapiens
           cDNA FLJ10718 fis, clone NT2RP3001096, weakly similar to
           Rattus norvegicus leprecan mRNA. ).
          Length = 527

 Score = 30.7 bits (66), Expect = 4.5
 Identities = 15/35 (42%), Positives = 21/35 (60%)
 Frame = -1

Query: 265 RVSQRCDHLLFDLILEKRRIIEARTSDNSDLYFSY 161
           RV  +   L +D+  + RRI+E+    NS LYFSY
Sbjct: 341 RVPLKSARLFYDISEKARRIVESYFMLNSTLYFSY 375


>AJ430351-1|CAD23039.2|  708|Homo sapiens leprecan-like 1 protein
           protein.
          Length = 708

 Score = 30.7 bits (66), Expect = 4.5
 Identities = 15/35 (42%), Positives = 21/35 (60%)
 Frame = -1

Query: 265 RVSQRCDHLLFDLILEKRRIIEARTSDNSDLYFSY 161
           RV  +   L +D+  + RRI+E+    NS LYFSY
Sbjct: 522 RVPLKSARLFYDISEKARRIVESYFMLNSTLYFSY 556


>DQ067453-1|AAZ23040.1| 1262|Homo sapiens diaphanous-1 protein.
          Length = 1262

 Score = 30.3 bits (65), Expect = 5.9
 Identities = 14/48 (29%), Positives = 22/48 (45%)
 Frame = -2

Query: 621 PPRLGPRXTVRRALSHNTPAAWAGGTRRADPPPCCRKTALPTPSPINE 478
           PP   P   +   +  ++P +  GGT  + PPP      +P P P+ E
Sbjct: 602 PPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPE 649


>BC117257-1|AAI17258.1| 1262|Homo sapiens diaphanous homolog 1
           (Drosophila) protein.
          Length = 1262

 Score = 30.3 bits (65), Expect = 5.9
 Identities = 14/48 (29%), Positives = 22/48 (45%)
 Frame = -2

Query: 621 PPRLGPRXTVRRALSHNTPAAWAGGTRRADPPPCCRKTALPTPSPINE 478
           PP   P   +   +  ++P +  GGT  + PPP      +P P P+ E
Sbjct: 602 PPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPE 649


>AY363395-1|AAQ63049.1| 1272|Homo sapiens diaphanous 1 protein.
          Length = 1272

 Score = 30.3 bits (65), Expect = 5.9
 Identities = 14/48 (29%), Positives = 22/48 (45%)
 Frame = -2

Query: 621 PPRLGPRXTVRRALSHNTPAAWAGGTRRADPPPCCRKTALPTPSPINE 478
           PP   P   +   +  ++P +  GGT  + PPP      +P P P+ E
Sbjct: 612 PPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPE 659


>AK128837-1|BAC87637.1|  286|Homo sapiens protein ( Homo sapiens
           cDNA FLJ46366 fis, clone TESTI4051388. ).
          Length = 286

 Score = 30.3 bits (65), Expect = 5.9
 Identities = 21/49 (42%), Positives = 23/49 (46%), Gaps = 2/49 (4%)
 Frame = -2

Query: 627 RVPPRLGPRXTVRRALSHNTP--AAWAGGTRRADPPPCCRKTALPTPSP 487
           R PPR  PR T  RA    TP  A+      RA PP     TA PT +P
Sbjct: 47  RTPPRASPRRTPPRASPRRTPPRASLTRPPTRA-PPTRMPPTAPPTRTP 94


>AK023345-1|BAB14533.1|  533|Homo sapiens protein ( Homo sapiens
           cDNA FLJ13283 fis, clone OVARC1001113, highly similar to
           Homo sapiens diaphanous 1 (HDIA1) mRNA. ).
          Length = 533

 Score = 30.3 bits (65), Expect = 5.9
 Identities = 14/48 (29%), Positives = 22/48 (45%)
 Frame = -2

Query: 621 PPRLGPRXTVRRALSHNTPAAWAGGTRRADPPPCCRKTALPTPSPINE 478
           PP   P   +   +  ++P +  GGT  + PPP      +P P P+ E
Sbjct: 379 PPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPE 426


>AF177663-1|AAD53166.1|  771|Homo sapiens GTPase-activating protein
           6 isoform 4 protein.
          Length = 771

 Score = 30.3 bits (65), Expect = 5.9
 Identities = 15/39 (38%), Positives = 19/39 (48%)
 Frame = +2

Query: 368 LIFGH*SKSAALTSSPRPPLGL*LKNTGLGIWSYWTISL 484
           ++ GH S S +  SSP P LG  L      IW  W  +L
Sbjct: 501 MLVGHLSSSKSRESSPGPRLGKDLSEEPFDIWGTWHSTL 539


>AF117067-1|AAF43261.1|  974|Homo sapiens rho-type GTPase-activating
           protein isoform 3 protein.
          Length = 974

 Score = 30.3 bits (65), Expect = 5.9
 Identities = 15/39 (38%), Positives = 19/39 (48%)
 Frame = +2

Query: 368 LIFGH*SKSAALTSSPRPPLGL*LKNTGLGIWSYWTISL 484
           ++ GH S S +  SSP P LG  L      IW  W  +L
Sbjct: 704 MLVGHLSSSKSRESSPGPRLGKDLSEEPFDIWGTWHSTL 742


>AB209482-1|BAD92719.1| 1299|Homo sapiens Diaphanous 1 variant
           protein.
          Length = 1299

 Score = 30.3 bits (65), Expect = 5.9
 Identities = 14/48 (29%), Positives = 22/48 (45%)
 Frame = -2

Query: 621 PPRLGPRXTVRRALSHNTPAAWAGGTRRADPPPCCRKTALPTPSPINE 478
           PP   P   +   +  ++P +  GGT  + PPP      +P P P+ E
Sbjct: 639 PPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPE 686


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 97,480,349
Number of Sequences: 237096
Number of extensions: 2364356
Number of successful extensions: 5507
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 5052
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5484
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6916500330
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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