Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= NV060315.seq
(686 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U20285-1|AAC50906.2| 500|Homo sapiens Gps1 protein. 159 6e-39
BT009834-1|AAP88836.1| 475|Homo sapiens G protein pathway suppr... 159 6e-39
BC064503-1|AAH64503.1| 527|Homo sapiens G protein pathway suppr... 159 6e-39
BC000155-1|AAH00155.3| 491|Homo sapiens G protein pathway suppr... 159 6e-39
AK093283-1|BAC04120.1| 549|Homo sapiens protein ( Homo sapiens ... 158 2e-38
AB209596-1|BAD92833.1| 284|Homo sapiens G protein pathway suppr... 155 2e-37
BC035315-1|AAH35315.1| 431|Homo sapiens THNSL2 protein protein. 30 6.7
AK001778-1|BAA91904.1| 265|Homo sapiens protein ( Homo sapiens ... 30 6.7
AC092836-2|AAX88906.1| 265|Homo sapiens unknown protein. 30 6.7
BC053538-1|AAH53538.1| 440|Homo sapiens tetratricopeptide repea... 30 8.9
BC030822-1|AAH30822.1| 440|Homo sapiens tetratricopeptide repea... 30 8.9
BC008647-1|AAH08647.1| 439|Homo sapiens TTC5 protein protein. 30 8.9
AK074553-1|BAC11056.1| 440|Homo sapiens protein ( Homo sapiens ... 30 8.9
>U20285-1|AAC50906.2| 500|Homo sapiens Gps1 protein.
Length = 500
Score = 159 bits (387), Expect = 6e-39
Identities = 82/136 (60%), Positives = 96/136 (70%), Gaps = 2/136 (1%)
Frame = +2
Query: 194 KKSCHKTGKARY*FEKL*NKSIKESIRRGHDDLGDHYLDCGDLTSALKCYSRARDYCTSG 373
KK+ K K + SIKESIRRGHDDLGDHYLDCGDL++ALKCYSRARDYCTS
Sbjct: 145 KKALLKLEKLDTDLKNYKGNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSRARDYCTSA 204
Query: 374 KHLVMMCLNVVKVSVYLQNWAHVLNYVSKAEATPDFNEIPG-KDSNSQF*LV-*NVQQD* 547
KH++ MCLNV+KVSVYLQNW+HVL+YVSKAE+TP+ E G +DS +Q L
Sbjct: 205 KHVINMCLNVIKVSVYLQNWSHVLSYVSKAESTPEIAEQRGERDSQTQAILTKLKCAAGL 264
Query: 548 PSWATKKYKSAAKHFL 595
A +KYK AAK L
Sbjct: 265 AELAARKYKQAAKCLL 280
Score = 126 bits (303), Expect = 1e-28
Identities = 80/231 (34%), Positives = 121/231 (52%), Gaps = 6/231 (2%)
Frame = +3
Query: 12 PSLRLEALKMAISYVMTTYNVNLYHTLHKKLSEAVASA-GLPDIAGSQDI--PVLDTIWV 182
P+LR+EALKMA+S+V T+NV++Y +H+KLSEA PD + P LDT WV
Sbjct: 81 PTLRVEALKMALSFVQRTFNVDMYEEIHRKLSEATRELQNAPDAIPESGVEPPALDTAWV 140
Query: 183 ESKTKKAAIKLEKLDTDLKNYKTNQSKK-VSEEAMMIWVTXXXXVEISPVP*NATRELEI 359
E+ KKA +KLEKLDTDLKNYK N K+ + + ++S +R +
Sbjct: 141 EATRKKALLKLEKLDTDLKNYKGNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSRARDY 200
Query: 360 TAQVENILS*CA*M*LKFQYIFKIGLMF*IMYLKLKRPQTLMKFPEKTATVN--FNSFKM 533
+++++ C + Y+ + + P+ + E+ + K
Sbjct: 201 CTSAKHVINMCLNVIKVSVYLQNWSHVLSYVSKAESTPEIAEQRGERDSQTQAILTKLKC 260
Query: 534 CSRISRAGQRKSINLLQNIFWAASIDHCEYPELMSSNNVAIYGGLCALATF 686
+ ++ RK + + AS DHC++PEL+S +NVAIYGGLCALATF
Sbjct: 261 AAGLAELAARKYKQAAKCLL-LASFDHCDFPELLSPSNVAIYGGLCALATF 310
>BT009834-1|AAP88836.1| 475|Homo sapiens G protein pathway
suppressor 1 protein.
Length = 475
Score = 159 bits (387), Expect = 6e-39
Identities = 82/136 (60%), Positives = 96/136 (70%), Gaps = 2/136 (1%)
Frame = +2
Query: 194 KKSCHKTGKARY*FEKL*NKSIKESIRRGHDDLGDHYLDCGDLTSALKCYSRARDYCTSG 373
KK+ K K + SIKESIRRGHDDLGDHYLDCGDL++ALKCYSRARDYCTS
Sbjct: 120 KKALLKLEKLDTDLKNYKGNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSRARDYCTSA 179
Query: 374 KHLVMMCLNVVKVSVYLQNWAHVLNYVSKAEATPDFNEIPG-KDSNSQF*LV-*NVQQD* 547
KH++ MCLNV+KVSVYLQNW+HVL+YVSKAE+TP+ E G +DS +Q L
Sbjct: 180 KHVINMCLNVIKVSVYLQNWSHVLSYVSKAESTPEIAEQRGERDSQTQAILTKLKCAAGL 239
Query: 548 PSWATKKYKSAAKHFL 595
A +KYK AAK L
Sbjct: 240 AELAARKYKQAAKCLL 255
Score = 125 bits (301), Expect = 2e-28
Identities = 81/235 (34%), Positives = 123/235 (52%), Gaps = 10/235 (4%)
Frame = +3
Query: 12 PSLRLEALKMAISYVMTTYNVNLYHTLHKKLSEAVASA-----GLPDIAGSQDI--PVLD 170
P+LR+EALKMA+S+V T+NV++Y +H+KLSEA S+ PD + P LD
Sbjct: 52 PTLRVEALKMALSFVQRTFNVDMYEEIHRKLSEATRSSLRELQNAPDAIPESGVEPPALD 111
Query: 171 TIWVESKTKKAAIKLEKLDTDLKNYKTNQSKK-VSEEAMMIWVTXXXXVEISPVP*NATR 347
T WVE+ KKA +KLEKLDTDLKNYK N K+ + + ++S +R
Sbjct: 112 TAWVEATRKKALLKLEKLDTDLKNYKGNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSR 171
Query: 348 ELEITAQVENILS*CA*M*LKFQYIFKIGLMF*IMYLKLKRPQTLMKFPEKTATVN--FN 521
+ +++++ C + Y+ + + P+ + E+ +
Sbjct: 172 ARDYCTSAKHVINMCLNVIKVSVYLQNWSHVLSYVSKAESTPEIAEQRGERDSQTQAILT 231
Query: 522 SFKMCSRISRAGQRKSINLLQNIFWAASIDHCEYPELMSSNNVAIYGGLCALATF 686
K + ++ RK + + AS DHC++PEL+S +NVAIYGGLCALATF
Sbjct: 232 KLKCAAGLAELAARKYKQAAKCLL-LASFDHCDFPELLSPSNVAIYGGLCALATF 285
>BC064503-1|AAH64503.1| 527|Homo sapiens G protein pathway
suppressor 1 protein.
Length = 527
Score = 159 bits (387), Expect = 6e-39
Identities = 82/136 (60%), Positives = 96/136 (70%), Gaps = 2/136 (1%)
Frame = +2
Query: 194 KKSCHKTGKARY*FEKL*NKSIKESIRRGHDDLGDHYLDCGDLTSALKCYSRARDYCTSG 373
KK+ K K + SIKESIRRGHDDLGDHYLDCGDL++ALKCYSRARDYCTS
Sbjct: 172 KKALLKLEKLDTDLKNYKGNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSRARDYCTSA 231
Query: 374 KHLVMMCLNVVKVSVYLQNWAHVLNYVSKAEATPDFNEIPG-KDSNSQF*LV-*NVQQD* 547
KH++ MCLNV+KVSVYLQNW+HVL+YVSKAE+TP+ E G +DS +Q L
Sbjct: 232 KHVINMCLNVIKVSVYLQNWSHVLSYVSKAESTPEIAEQRGERDSQTQAILTKLKCAAGL 291
Query: 548 PSWATKKYKSAAKHFL 595
A +KYK AAK L
Sbjct: 292 AELAARKYKQAAKCLL 307
Score = 126 bits (303), Expect = 1e-28
Identities = 80/231 (34%), Positives = 121/231 (52%), Gaps = 6/231 (2%)
Frame = +3
Query: 12 PSLRLEALKMAISYVMTTYNVNLYHTLHKKLSEAVASA-GLPDIAGSQDI--PVLDTIWV 182
P+LR+EALKMA+S+V T+NV++Y +H+KLSEA PD + P LDT WV
Sbjct: 108 PTLRVEALKMALSFVQRTFNVDMYEEIHRKLSEATRELQNAPDAIPESGVEPPALDTAWV 167
Query: 183 ESKTKKAAIKLEKLDTDLKNYKTNQSKK-VSEEAMMIWVTXXXXVEISPVP*NATRELEI 359
E+ KKA +KLEKLDTDLKNYK N K+ + + ++S +R +
Sbjct: 168 EATRKKALLKLEKLDTDLKNYKGNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSRARDY 227
Query: 360 TAQVENILS*CA*M*LKFQYIFKIGLMF*IMYLKLKRPQTLMKFPEKTATVN--FNSFKM 533
+++++ C + Y+ + + P+ + E+ + K
Sbjct: 228 CTSAKHVINMCLNVIKVSVYLQNWSHVLSYVSKAESTPEIAEQRGERDSQTQAILTKLKC 287
Query: 534 CSRISRAGQRKSINLLQNIFWAASIDHCEYPELMSSNNVAIYGGLCALATF 686
+ ++ RK + + AS DHC++PEL+S +NVAIYGGLCALATF
Sbjct: 288 AAGLAELAARKYKQAAKCLL-LASFDHCDFPELLSPSNVAIYGGLCALATF 337
>BC000155-1|AAH00155.3| 491|Homo sapiens G protein pathway
suppressor 1 protein.
Length = 491
Score = 159 bits (387), Expect = 6e-39
Identities = 82/136 (60%), Positives = 96/136 (70%), Gaps = 2/136 (1%)
Frame = +2
Query: 194 KKSCHKTGKARY*FEKL*NKSIKESIRRGHDDLGDHYLDCGDLTSALKCYSRARDYCTSG 373
KK+ K K + SIKESIRRGHDDLGDHYLDCGDL++ALKCYSRARDYCTS
Sbjct: 136 KKALLKLEKLDTDLKNYKGNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSRARDYCTSA 195
Query: 374 KHLVMMCLNVVKVSVYLQNWAHVLNYVSKAEATPDFNEIPG-KDSNSQF*LV-*NVQQD* 547
KH++ MCLNV+KVSVYLQNW+HVL+YVSKAE+TP+ E G +DS +Q L
Sbjct: 196 KHVINMCLNVIKVSVYLQNWSHVLSYVSKAESTPEIAEQRGERDSQTQAILTKLKCAAGL 255
Query: 548 PSWATKKYKSAAKHFL 595
A +KYK AAK L
Sbjct: 256 AELAARKYKQAAKCLL 271
Score = 125 bits (301), Expect = 2e-28
Identities = 81/235 (34%), Positives = 123/235 (52%), Gaps = 10/235 (4%)
Frame = +3
Query: 12 PSLRLEALKMAISYVMTTYNVNLYHTLHKKLSEAVASA-----GLPDIAGSQDI--PVLD 170
P+LR+EALKMA+S+V T+NV++Y +H+KLSEA S+ PD + P LD
Sbjct: 68 PTLRVEALKMALSFVQRTFNVDMYEEIHRKLSEATRSSLRELQNAPDAIPESGVEPPALD 127
Query: 171 TIWVESKTKKAAIKLEKLDTDLKNYKTNQSKK-VSEEAMMIWVTXXXXVEISPVP*NATR 347
T WVE+ KKA +KLEKLDTDLKNYK N K+ + + ++S +R
Sbjct: 128 TAWVEATRKKALLKLEKLDTDLKNYKGNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSR 187
Query: 348 ELEITAQVENILS*CA*M*LKFQYIFKIGLMF*IMYLKLKRPQTLMKFPEKTATVN--FN 521
+ +++++ C + Y+ + + P+ + E+ +
Sbjct: 188 ARDYCTSAKHVINMCLNVIKVSVYLQNWSHVLSYVSKAESTPEIAEQRGERDSQTQAILT 247
Query: 522 SFKMCSRISRAGQRKSINLLQNIFWAASIDHCEYPELMSSNNVAIYGGLCALATF 686
K + ++ RK + + AS DHC++PEL+S +NVAIYGGLCALATF
Sbjct: 248 KLKCAAGLAELAARKYKQAAKCLL-LASFDHCDFPELLSPSNVAIYGGLCALATF 301
>AK093283-1|BAC04120.1| 549|Homo sapiens protein ( Homo sapiens
cDNA FLJ35964 fis, clone TESTI2012592, highly similar to
G PROTEIN PATHWAY SUPPRESSOR 1. ).
Length = 549
Score = 158 bits (383), Expect = 2e-38
Identities = 81/136 (59%), Positives = 95/136 (69%), Gaps = 2/136 (1%)
Frame = +2
Query: 194 KKSCHKTGKARY*FEKL*NKSIKESIRRGHDDLGDHYLDCGDLTSALKCYSRARDYCTSG 373
KK+ K K + SIKESIRRGHDDLGDHYLDCGDL++ALKCYSRARDYCTS
Sbjct: 121 KKALLKLEKLDTDLKNYKGNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSRARDYCTSA 180
Query: 374 KHLVMMCLNVVKVSVYLQNWAHVLNYVSKAEATPDFNEIPG-KDSNSQF*LV-*NVQQD* 547
KH++ MCLNV+KVSVYLQNW+HVL+YVSKAE+TP+ E G +DS +Q L
Sbjct: 181 KHVINMCLNVIKVSVYLQNWSHVLSYVSKAESTPEIAEQRGERDSQTQAILTKLKCAAGL 240
Query: 548 PSWATKKYKSAAKHFL 595
+KYK AAK L
Sbjct: 241 AELTARKYKQAAKCLL 256
Score = 84.2 bits (199), Expect = 4e-16
Identities = 57/179 (31%), Positives = 88/179 (49%), Gaps = 3/179 (1%)
Frame = +3
Query: 159 PVLDTIWVESKTKKAAIKLEKLDTDLKNYKTNQSKK-VSEEAMMIWVTXXXXVEISPVP* 335
P LDT WVE+ KKA +KLEKLDTDLKNYK N K+ + + ++S
Sbjct: 109 PALDTAWVEATRKKALLKLEKLDTDLKNYKGNSIKESIRRGHDDLGDHYLDCGDLSNALK 168
Query: 336 NATRELEITAQVENILS*CA*M*LKFQYIFKIGLMF*IMYLKLKRPQTLMKFPEKTATVN 515
+R + +++++ C + Y+ + + P+ + E+ +
Sbjct: 169 CYSRARDYCTSAKHVINMCLNVIKVSVYLQNWSHVLSYVSKAESTPEIAEQRGERDSQTQ 228
Query: 516 --FNSFKMCSRISRAGQRKSINLLQNIFWAASIDHCEYPELMSSNNVAIYGGLCALATF 686
K + ++ RK + + AS DHC++PEL+S +NVAIYGGLCALATF
Sbjct: 229 AILTKLKCAAGLAELTARKYKQAAKCLL-LASFDHCDFPELLSPSNVAIYGGLCALATF 286
>AB209596-1|BAD92833.1| 284|Homo sapiens G protein pathway
suppressor 1 isoform 2 variant protein.
Length = 284
Score = 155 bits (375), Expect = 2e-37
Identities = 70/106 (66%), Positives = 83/106 (78%)
Frame = +2
Query: 194 KKSCHKTGKARY*FEKL*NKSIKESIRRGHDDLGDHYLDCGDLTSALKCYSRARDYCTSG 373
KK+ K K + SIKESIRRGHDDLGDHYLDCGDL++ALKCYSRARDYCTS
Sbjct: 57 KKALLKLEKLDTDLKNYKGNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSRARDYCTSA 116
Query: 374 KHLVMMCLNVVKVSVYLQNWAHVLNYVSKAEATPDFNEIPGKDSNS 511
KH++ MCLNV+KVSVYLQNW+HVL+YVSKAE+TP+ E+ S +
Sbjct: 117 KHVINMCLNVIKVSVYLQNWSHVLSYVSKAESTPEIAEVRATSSET 162
Score = 56.4 bits (130), Expect = 9e-08
Identities = 25/36 (69%), Positives = 28/36 (77%)
Frame = +3
Query: 159 PVLDTIWVESKTKKAAIKLEKLDTDLKNYKTNQSKK 266
P LDT WVE+ KKA +KLEKLDTDLKNYK N K+
Sbjct: 45 PALDTAWVEATRKKALLKLEKLDTDLKNYKGNSIKE 80
>BC035315-1|AAH35315.1| 431|Homo sapiens THNSL2 protein protein.
Length = 431
Score = 30.3 bits (65), Expect = 6.7
Identities = 16/30 (53%), Positives = 19/30 (63%)
Frame = +3
Query: 63 TYNVNLYHTLHKKLSEAVASAGLPDIAGSQ 152
T +VNL LH KLSEAV S + D A +Q
Sbjct: 294 TQSVNLPKELHSKLSEAVTSVSVSDEAITQ 323
>AK001778-1|BAA91904.1| 265|Homo sapiens protein ( Homo sapiens
cDNA FLJ10916 fis, clone OVARC1000309, weakly similar to
THREONINE SYNTHASE (EC 4.2.99.2). ).
Length = 265
Score = 30.3 bits (65), Expect = 6.7
Identities = 16/30 (53%), Positives = 19/30 (63%)
Frame = +3
Query: 63 TYNVNLYHTLHKKLSEAVASAGLPDIAGSQ 152
T +VNL LH KLSEAV S + D A +Q
Sbjct: 128 TQSVNLPKELHSKLSEAVTSVSVSDEAITQ 157
>AC092836-2|AAX88906.1| 265|Homo sapiens unknown protein.
Length = 265
Score = 30.3 bits (65), Expect = 6.7
Identities = 16/30 (53%), Positives = 19/30 (63%)
Frame = +3
Query: 63 TYNVNLYHTLHKKLSEAVASAGLPDIAGSQ 152
T +VNL LH KLSEAV S + D A +Q
Sbjct: 128 TQSVNLPKELHSKLSEAVTSVSVSDEAITQ 157
>BC053538-1|AAH53538.1| 440|Homo sapiens tetratricopeptide repeat
domain 5 protein.
Length = 440
Score = 29.9 bits (64), Expect = 8.9
Identities = 21/81 (25%), Positives = 42/81 (51%), Gaps = 4/81 (4%)
Frame = +2
Query: 236 EKL*NKSIK--ESIRRGHDDLGDHYLDCGDLTSALKCYSRARDYCTSGKHL--VMMCLNV 403
E+L +K++K + + LG+ Y GD+ +A C+S A +C + L + M L
Sbjct: 89 EELLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGALTHCRNKVSLQNLSMVLRQ 148
Query: 404 VKVSVYLQNWAHVLNYVSKAE 466
++ ++ HV++ V +A+
Sbjct: 149 LRTDTEDEHSHHVMDSVRQAK 169
>BC030822-1|AAH30822.1| 440|Homo sapiens tetratricopeptide repeat
domain 5 protein.
Length = 440
Score = 29.9 bits (64), Expect = 8.9
Identities = 21/81 (25%), Positives = 42/81 (51%), Gaps = 4/81 (4%)
Frame = +2
Query: 236 EKL*NKSIK--ESIRRGHDDLGDHYLDCGDLTSALKCYSRARDYCTSGKHL--VMMCLNV 403
E+L +K++K + + LG+ Y GD+ +A C+S A +C + L + M L
Sbjct: 89 EELLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGALTHCRNKVSLQNLSMVLRQ 148
Query: 404 VKVSVYLQNWAHVLNYVSKAE 466
++ ++ HV++ V +A+
Sbjct: 149 LRTDTEDEHSHHVMDSVRQAK 169
>BC008647-1|AAH08647.1| 439|Homo sapiens TTC5 protein protein.
Length = 439
Score = 29.9 bits (64), Expect = 8.9
Identities = 21/81 (25%), Positives = 42/81 (51%), Gaps = 4/81 (4%)
Frame = +2
Query: 236 EKL*NKSIK--ESIRRGHDDLGDHYLDCGDLTSALKCYSRARDYCTSGKHL--VMMCLNV 403
E+L +K++K + + LG+ Y GD+ +A C+S A +C + L + M L
Sbjct: 88 EELLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGALTHCRNKVSLQNLSMVLRQ 147
Query: 404 VKVSVYLQNWAHVLNYVSKAE 466
++ ++ HV++ V +A+
Sbjct: 148 LRTDTEDEHSHHVMDSVRQAK 168
>AK074553-1|BAC11056.1| 440|Homo sapiens protein ( Homo sapiens
cDNA FLJ90072 fis, clone HEMBA1004085. ).
Length = 440
Score = 29.9 bits (64), Expect = 8.9
Identities = 21/81 (25%), Positives = 42/81 (51%), Gaps = 4/81 (4%)
Frame = +2
Query: 236 EKL*NKSIK--ESIRRGHDDLGDHYLDCGDLTSALKCYSRARDYCTSGKHL--VMMCLNV 403
E+L +K++K + + LG+ Y GD+ +A C+S A +C + L + M L
Sbjct: 89 EELLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGALTHCRNKVSLQNLSMVLRQ 148
Query: 404 VKVSVYLQNWAHVLNYVSKAE 466
++ ++ HV++ V +A+
Sbjct: 149 LRTDTEDEHSHHVMDSVRQAK 169
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 89,571,421
Number of Sequences: 237096
Number of extensions: 1702558
Number of successful extensions: 3428
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 3169
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3419
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7839245960
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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