Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= NV060282.seq
(678 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BT007307-1|AAP35971.1| 376|Homo sapiens proteasome (prosome, ma... 97 7e-20
BC001747-1|AAH01747.1| 376|Homo sapiens proteasome (prosome, ma... 97 7e-20
BC001100-1|AAH01100.1| 376|Homo sapiens proteasome (prosome, ma... 97 7e-20
AF107837-1|AAD43442.1| 376|Homo sapiens 26S proteasome subunit ... 97 7e-20
AF086708-1|AAC64104.1| 376|Homo sapiens 26S proteasome subunit ... 97 7e-20
AK222895-1|BAD96615.1| 376|Homo sapiens proteasome 26S non-ATPa... 95 2e-19
AB009398-1|BAA33214.1| 376|Homo sapiens 26S proteasome subunit ... 95 2e-19
BC025275-1|AAH25275.1| 483|Homo sapiens ATPase, H+ transporting... 33 1.2
AF298777-1|AAG22809.1| 483|Homo sapiens vacuolar ATPase subunit... 33 1.2
AF132945-1|AAD27720.1| 483|Homo sapiens CGI-11 protein protein. 33 1.2
AF125105-1|AAL75942.1| 476|Homo sapiens vacuolar proton pump su... 33 1.2
AF112204-1|AAF17192.1| 483|Homo sapiens Vacuolar proton pump su... 33 1.2
AF111162-1|AAD43651.1| 1849|Homo sapiens guanine nucleotide exch... 31 5.0
AF084520-1|AAD38427.1| 1849|Homo sapiens brefeldin A-inhibited g... 31 5.0
AB209324-1|BAD92561.1| 1278|Homo sapiens brefeldin A-inhibited g... 31 5.0
>BT007307-1|AAP35971.1| 376|Homo sapiens proteasome (prosome,
macropain) 26S subunit, non-ATPase, 13 protein.
Length = 376
Score = 96.7 bits (230), Expect = 7e-20
Identities = 42/79 (53%), Positives = 58/79 (73%)
Frame = +1
Query: 34 DVSDFLTKKQASEPALAADWAKLEELYNKKLWHQLTLKLQEFVKNPALQRGDNLIQLYNN 213
DV FL + Q+S P A W +LEELY KKLWHQLTL++ +FV++P +GD LI+LY N
Sbjct: 3 DVPGFLQQSQSSGPGQPAVWHRLEELYTKKLWHQLTLQVLDFVQDPCFAQGDGLIKLYEN 62
Query: 214 FLTTFESKINPLSLLRSLL 270
F++ FE ++NPLSL+ +L
Sbjct: 63 FISEFEHRVNPLSLVEIIL 81
Score = 54.0 bits (124), Expect = 5e-07
Identities = 27/65 (41%), Positives = 39/65 (60%)
Frame = +3
Query: 252 IVEIIAHIVEQYVNKRDAVTFLEKVETKVKMNDEALALCKVLQGQIYIEQLNDYDAAEKI 431
+VEII H+V Q + A+TFLEK KVK +DEA+ LCK G + + + D ++
Sbjct: 76 LVEIILHVVRQMTDPNVALTFLEKTREKVKSSDEAVILCKTAIGALKL-NIGDLQVTKET 134
Query: 432 IEHLE 446
IE +E
Sbjct: 135 IEDVE 139
Score = 41.1 bits (92), Expect = 0.004
Identities = 19/43 (44%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Frame = +2
Query: 452 LEDADGVTPVHGRFYKLASNITESV-VPLPYYRAALRYVGCAD 577
L + GVT VH RFY L+S +++ YY+ ALR++GC D
Sbjct: 142 LNNLPGVTSVHSRFYDLSSKYYQTIGNHASYYKDALRFLGCVD 184
>BC001747-1|AAH01747.1| 376|Homo sapiens proteasome (prosome,
macropain) 26S subunit, non-ATPase, 13 protein.
Length = 376
Score = 96.7 bits (230), Expect = 7e-20
Identities = 42/79 (53%), Positives = 58/79 (73%)
Frame = +1
Query: 34 DVSDFLTKKQASEPALAADWAKLEELYNKKLWHQLTLKLQEFVKNPALQRGDNLIQLYNN 213
DV FL + Q+S P A W +LEELY KKLWHQLTL++ +FV++P +GD LI+LY N
Sbjct: 3 DVPGFLQQSQSSGPGQPAVWHRLEELYTKKLWHQLTLQVLDFVQDPCFAQGDGLIKLYEN 62
Query: 214 FLTTFESKINPLSLLRSLL 270
F++ FE ++NPLSL+ +L
Sbjct: 63 FISEFEHRVNPLSLVEIIL 81
Score = 54.0 bits (124), Expect = 5e-07
Identities = 27/65 (41%), Positives = 39/65 (60%)
Frame = +3
Query: 252 IVEIIAHIVEQYVNKRDAVTFLEKVETKVKMNDEALALCKVLQGQIYIEQLNDYDAAEKI 431
+VEII H+V Q + A+TFLEK KVK +DEA+ LCK G + + + D ++
Sbjct: 76 LVEIILHVVRQMTDPNVALTFLEKTREKVKSSDEAVILCKTAIGALKL-NIGDLQVTKET 134
Query: 432 IEHLE 446
IE +E
Sbjct: 135 IEDVE 139
Score = 41.1 bits (92), Expect = 0.004
Identities = 19/43 (44%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Frame = +2
Query: 452 LEDADGVTPVHGRFYKLASNITESV-VPLPYYRAALRYVGCAD 577
L + GVT VH RFY L+S +++ YY+ ALR++GC D
Sbjct: 142 LNNLPGVTSVHSRFYDLSSKYYQTIGNHASYYKDALRFLGCVD 184
>BC001100-1|AAH01100.1| 376|Homo sapiens proteasome (prosome,
macropain) 26S subunit, non-ATPase, 13 protein.
Length = 376
Score = 96.7 bits (230), Expect = 7e-20
Identities = 42/79 (53%), Positives = 58/79 (73%)
Frame = +1
Query: 34 DVSDFLTKKQASEPALAADWAKLEELYNKKLWHQLTLKLQEFVKNPALQRGDNLIQLYNN 213
DV FL + Q+S P A W +LEELY KKLWHQLTL++ +FV++P +GD LI+LY N
Sbjct: 3 DVPGFLQQSQSSGPGQPAVWHRLEELYTKKLWHQLTLQVLDFVQDPCFAQGDGLIKLYEN 62
Query: 214 FLTTFESKINPLSLLRSLL 270
F++ FE ++NPLSL+ +L
Sbjct: 63 FISEFEHRVNPLSLVEIIL 81
Score = 54.0 bits (124), Expect = 5e-07
Identities = 27/65 (41%), Positives = 39/65 (60%)
Frame = +3
Query: 252 IVEIIAHIVEQYVNKRDAVTFLEKVETKVKMNDEALALCKVLQGQIYIEQLNDYDAAEKI 431
+VEII H+V Q + A+TFLEK KVK +DEA+ LCK G + + + D ++
Sbjct: 76 LVEIILHVVRQMTDPNVALTFLEKTREKVKSSDEAVILCKTAIGALKL-NIGDLQVTKET 134
Query: 432 IEHLE 446
IE +E
Sbjct: 135 IEDVE 139
Score = 41.1 bits (92), Expect = 0.004
Identities = 19/43 (44%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Frame = +2
Query: 452 LEDADGVTPVHGRFYKLASNITESV-VPLPYYRAALRYVGCAD 577
L + GVT VH RFY L+S +++ YY+ ALR++GC D
Sbjct: 142 LNNLPGVTSVHSRFYDLSSKYYQTIGNHASYYKDALRFLGCVD 184
>AF107837-1|AAD43442.1| 376|Homo sapiens 26S proteasome subunit
p40.5 protein.
Length = 376
Score = 96.7 bits (230), Expect = 7e-20
Identities = 42/79 (53%), Positives = 58/79 (73%)
Frame = +1
Query: 34 DVSDFLTKKQASEPALAADWAKLEELYNKKLWHQLTLKLQEFVKNPALQRGDNLIQLYNN 213
DV FL + Q+S P A W +LEELY KKLWHQLTL++ +FV++P +GD LI+LY N
Sbjct: 3 DVPGFLQQSQSSGPGQPAVWHRLEELYTKKLWHQLTLQVLDFVQDPCFAQGDGLIKLYEN 62
Query: 214 FLTTFESKINPLSLLRSLL 270
F++ FE ++NPLSL+ +L
Sbjct: 63 FISEFEHRVNPLSLVEIIL 81
Score = 54.0 bits (124), Expect = 5e-07
Identities = 27/65 (41%), Positives = 39/65 (60%)
Frame = +3
Query: 252 IVEIIAHIVEQYVNKRDAVTFLEKVETKVKMNDEALALCKVLQGQIYIEQLNDYDAAEKI 431
+VEII H+V Q + A+TFLEK KVK +DEA+ LCK G + + + D ++
Sbjct: 76 LVEIILHVVRQMTDPNVALTFLEKTREKVKSSDEAVILCKTAIGALKL-NIGDLQVTKET 134
Query: 432 IEHLE 446
IE +E
Sbjct: 135 IEDVE 139
Score = 41.1 bits (92), Expect = 0.004
Identities = 19/43 (44%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Frame = +2
Query: 452 LEDADGVTPVHGRFYKLASNITESV-VPLPYYRAALRYVGCAD 577
L + GVT VH RFY L+S +++ YY+ ALR++GC D
Sbjct: 142 LNNLPGVTSVHSRFYDLSSKYYQTIGNHASYYKDALRFLGCVD 184
>AF086708-1|AAC64104.1| 376|Homo sapiens 26S proteasome subunit 11
protein.
Length = 376
Score = 96.7 bits (230), Expect = 7e-20
Identities = 42/79 (53%), Positives = 58/79 (73%)
Frame = +1
Query: 34 DVSDFLTKKQASEPALAADWAKLEELYNKKLWHQLTLKLQEFVKNPALQRGDNLIQLYNN 213
DV FL + Q+S P A W +LEELY KKLWHQLTL++ +FV++P +GD LI+LY N
Sbjct: 3 DVPGFLQQSQSSGPGQPAVWHRLEELYTKKLWHQLTLQVLDFVQDPCFAQGDGLIKLYEN 62
Query: 214 FLTTFESKINPLSLLRSLL 270
F++ FE ++NPLSL+ +L
Sbjct: 63 FISEFEHRVNPLSLVEIIL 81
Score = 54.0 bits (124), Expect = 5e-07
Identities = 27/65 (41%), Positives = 39/65 (60%)
Frame = +3
Query: 252 IVEIIAHIVEQYVNKRDAVTFLEKVETKVKMNDEALALCKVLQGQIYIEQLNDYDAAEKI 431
+VEII H+V Q + A+TFLEK KVK +DEA+ LCK G + + + D ++
Sbjct: 76 LVEIILHVVRQMTDPNVALTFLEKTREKVKSSDEAVILCKTAIGALKL-NIGDLQVTKET 134
Query: 432 IEHLE 446
IE +E
Sbjct: 135 IEDVE 139
Score = 41.1 bits (92), Expect = 0.004
Identities = 19/43 (44%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Frame = +2
Query: 452 LEDADGVTPVHGRFYKLASNITESV-VPLPYYRAALRYVGCAD 577
L + GVT VH RFY L+S +++ YY+ ALR++GC D
Sbjct: 142 LNNLPGVTSVHSRFYDLSSKYYQTIGNHASYYKDALRFLGCVD 184
>AK222895-1|BAD96615.1| 376|Homo sapiens proteasome 26S non-ATPase
subunit 13 isoform 1 variant protein.
Length = 376
Score = 95.5 bits (227), Expect = 2e-19
Identities = 42/79 (53%), Positives = 57/79 (72%)
Frame = +1
Query: 34 DVSDFLTKKQASEPALAADWAKLEELYNKKLWHQLTLKLQEFVKNPALQRGDNLIQLYNN 213
DV FL + Q S P A W +LEELY KKLWHQLTL++ +FV++P +GD LI+LY N
Sbjct: 3 DVPGFLQQSQNSGPGQPAVWHRLEELYTKKLWHQLTLQVLDFVQDPCFAQGDGLIKLYEN 62
Query: 214 FLTTFESKINPLSLLRSLL 270
F++ FE ++NPLSL+ +L
Sbjct: 63 FISEFEHRVNPLSLVEIIL 81
Score = 54.0 bits (124), Expect = 5e-07
Identities = 27/65 (41%), Positives = 39/65 (60%)
Frame = +3
Query: 252 IVEIIAHIVEQYVNKRDAVTFLEKVETKVKMNDEALALCKVLQGQIYIEQLNDYDAAEKI 431
+VEII H+V Q + A+TFLEK KVK +DEA+ LCK G + + + D ++
Sbjct: 76 LVEIILHVVRQMTDPNVALTFLEKTREKVKSSDEAVILCKTAIGALKL-NIGDLQVTKET 134
Query: 432 IEHLE 446
IE +E
Sbjct: 135 IEDVE 139
Score = 39.5 bits (88), Expect = 0.011
Identities = 18/43 (41%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Frame = +2
Query: 452 LEDADGVTPVHGRFYKLASNITESV-VPLPYYRAALRYVGCAD 577
L + GVT VH RFY L+S +++ YY+ AL+++GC D
Sbjct: 142 LNNLPGVTSVHSRFYDLSSKYYQTIGNHASYYKDALQFLGCVD 184
>AB009398-1|BAA33214.1| 376|Homo sapiens 26S proteasome subunit
p40.5 protein.
Length = 376
Score = 95.5 bits (227), Expect = 2e-19
Identities = 42/79 (53%), Positives = 57/79 (72%)
Frame = +1
Query: 34 DVSDFLTKKQASEPALAADWAKLEELYNKKLWHQLTLKLQEFVKNPALQRGDNLIQLYNN 213
DV FL + Q S P A W +LEELY KKLWHQLTL++ +FV++P +GD LI+LY N
Sbjct: 3 DVPGFLQQSQNSGPGQPAVWHRLEELYTKKLWHQLTLQVLDFVQDPCFAQGDGLIKLYEN 62
Query: 214 FLTTFESKINPLSLLRSLL 270
F++ FE ++NPLSL+ +L
Sbjct: 63 FISEFEHRVNPLSLVEIIL 81
Score = 54.0 bits (124), Expect = 5e-07
Identities = 27/65 (41%), Positives = 39/65 (60%)
Frame = +3
Query: 252 IVEIIAHIVEQYVNKRDAVTFLEKVETKVKMNDEALALCKVLQGQIYIEQLNDYDAAEKI 431
+VEII H+V Q + A+TFLEK KVK +DEA+ LCK G + + + D ++
Sbjct: 76 LVEIILHVVRQMTDPNVALTFLEKTREKVKSSDEAVILCKTAIGALKL-NIGDLQVTKET 134
Query: 432 IEHLE 446
IE +E
Sbjct: 135 IEDVE 139
Score = 41.1 bits (92), Expect = 0.004
Identities = 19/43 (44%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Frame = +2
Query: 452 LEDADGVTPVHGRFYKLASNITESV-VPLPYYRAALRYVGCAD 577
L + GVT VH RFY L+S +++ YY+ ALR++GC D
Sbjct: 142 LNNLPGVTSVHSRFYDLSSKYYQTIGNHASYYKDALRFLGCVD 184
>BC025275-1|AAH25275.1| 483|Homo sapiens ATPase, H+ transporting,
lysosomal 50/57kDa, V1 subunit H protein.
Length = 483
Score = 32.7 bits (71), Expect = 1.2
Identities = 25/78 (32%), Positives = 41/78 (52%), Gaps = 7/78 (8%)
Frame = +3
Query: 219 DHLRKQNKSPIIVEIIAHIVEQYVNKRDAV---TFLEKVETKVKMNDEALAL--CKVLQG 383
+HLR+ N P++ +I+ V++ V + FLEK + + ALA+ CKVL+
Sbjct: 258 EHLRRYNIIPVLSDILQESVKEKVTRIILAAFRNFLEKSTERETRQEYALAMIQCKVLKQ 317
Query: 384 QIYIEQ--LNDYDAAEKI 431
+EQ +D D +E I
Sbjct: 318 LENLEQQKYDDEDISEDI 335
>AF298777-1|AAG22809.1| 483|Homo sapiens vacuolar ATPase subunit H
protein.
Length = 483
Score = 32.7 bits (71), Expect = 1.2
Identities = 25/78 (32%), Positives = 41/78 (52%), Gaps = 7/78 (8%)
Frame = +3
Query: 219 DHLRKQNKSPIIVEIIAHIVEQYVNKRDAV---TFLEKVETKVKMNDEALAL--CKVLQG 383
+HLR+ N P++ +I+ V++ V + FLEK + + ALA+ CKVL+
Sbjct: 258 EHLRRYNIIPVLSDILQESVKEKVTRIILAAFRNFLEKSTERETRQEYALAMIQCKVLKQ 317
Query: 384 QIYIEQ--LNDYDAAEKI 431
+EQ +D D +E I
Sbjct: 318 LENLEQQKYDDEDISEDI 335
>AF132945-1|AAD27720.1| 483|Homo sapiens CGI-11 protein protein.
Length = 483
Score = 32.7 bits (71), Expect = 1.2
Identities = 25/78 (32%), Positives = 41/78 (52%), Gaps = 7/78 (8%)
Frame = +3
Query: 219 DHLRKQNKSPIIVEIIAHIVEQYVNKRDAV---TFLEKVETKVKMNDEALAL--CKVLQG 383
+HLR+ N P++ +I+ V++ V + FLEK + + ALA+ CKVL+
Sbjct: 258 EHLRRYNIIPVLSDILQESVKEKVTRIILAAFRNFLEKSTERETRQEYALAMIQCKVLKQ 317
Query: 384 QIYIEQ--LNDYDAAEKI 431
+EQ +D D +E I
Sbjct: 318 LENLEQQKYDDEDISEDI 335
>AF125105-1|AAL75942.1| 476|Homo sapiens vacuolar proton pump
subunit SFD alpha isoform protein.
Length = 476
Score = 32.7 bits (71), Expect = 1.2
Identities = 25/78 (32%), Positives = 41/78 (52%), Gaps = 7/78 (8%)
Frame = +3
Query: 219 DHLRKQNKSPIIVEIIAHIVEQYVNKRDAV---TFLEKVETKVKMNDEALAL--CKVLQG 383
+HLR+ N P++ +I+ V++ V + FLEK + + ALA+ CKVL+
Sbjct: 258 EHLRRYNIIPVLSDILQESVKEKVTRIILAAFRNFLEKSTERETRQEYALAMIQCKVLKQ 317
Query: 384 QIYIEQ--LNDYDAAEKI 431
+EQ +D D +E I
Sbjct: 318 LENLEQQKYDDEDISEDI 335
>AF112204-1|AAF17192.1| 483|Homo sapiens Vacuolar proton pump
subunit SFD alpha isoform protein.
Length = 483
Score = 32.7 bits (71), Expect = 1.2
Identities = 25/78 (32%), Positives = 41/78 (52%), Gaps = 7/78 (8%)
Frame = +3
Query: 219 DHLRKQNKSPIIVEIIAHIVEQYVNKRDAV---TFLEKVETKVKMNDEALAL--CKVLQG 383
+HLR+ N P++ +I+ V++ V + FLEK + + ALA+ CKVL+
Sbjct: 258 EHLRRYNIIPVLSDILQESVKEKVTRIILAAFRNFLEKSTERETRQEYALAMIQCKVLKQ 317
Query: 384 QIYIEQ--LNDYDAAEKI 431
+EQ +D D +E I
Sbjct: 318 LENLEQQKYDDEDISEDI 335
>AF111162-1|AAD43651.1| 1849|Homo sapiens guanine nucleotide exchange
factor protein.
Length = 1849
Score = 30.7 bits (66), Expect = 5.0
Identities = 11/30 (36%), Positives = 20/30 (66%)
Frame = +3
Query: 216 FDHLRKQNKSPIIVEIIAHIVEQYVNKRDA 305
F+H+ K+N+SP I +++ + Q VN + A
Sbjct: 1240 FEHIMKRNRSPTIRDMVVRCIAQMVNSQAA 1269
>AF084520-1|AAD38427.1| 1849|Homo sapiens brefeldin A-inhibited
guanine nucleotide-exchange protein 1 protein.
Length = 1849
Score = 30.7 bits (66), Expect = 5.0
Identities = 11/30 (36%), Positives = 20/30 (66%)
Frame = +3
Query: 216 FDHLRKQNKSPIIVEIIAHIVEQYVNKRDA 305
F+H+ K+N+SP I +++ + Q VN + A
Sbjct: 1240 FEHIMKRNRSPTIRDMVVRCIAQMVNSQAA 1269
>AB209324-1|BAD92561.1| 1278|Homo sapiens brefeldin A-inhibited
guanine nucleotide-exchange protein 1 variant protein.
Length = 1278
Score = 30.7 bits (66), Expect = 5.0
Identities = 11/30 (36%), Positives = 20/30 (66%)
Frame = +3
Query: 216 FDHLRKQNKSPIIVEIIAHIVEQYVNKRDA 305
F+H+ K+N+SP I +++ + Q VN + A
Sbjct: 718 FEHIMKRNRSPTIRDMVVRCIAQMVNSQAA 747
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 94,205,902
Number of Sequences: 237096
Number of extensions: 2014312
Number of successful extensions: 4068
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 3848
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4059
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7671262118
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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