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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= NV060259.seq
         (685 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC071562-1|AAH71562.2| 1235|Homo sapiens NOTCH2 protein protein.       31   2.9  
AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2 (Drosop...    31   2.9  
AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2 (Drosop...    31   2.9  
AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2 (Drosop...    31   2.9  
AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein.       31   2.9  
AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein.              31   2.9  
X52541-1|CAA36777.1|  543|Homo sapiens protein ( Human mRNA for ...    31   3.8  
M62829-1|AAA35815.1|  543|Homo sapiens ETR103 protein.                 31   3.8  
BC073983-1|AAH73983.1|  543|Homo sapiens early growth response 1...    31   3.8  
AJ243425-1|CAB46678.1|  543|Homo sapiens early growth response p...    31   3.8  
X80289-1|CAA56563.1| 2466|Homo sapiens protein-tyrosine-phosphat...    31   5.0  
X79676-1|CAA56124.1| 1267|Homo sapiens tyrosine phosphatase prot...    31   5.0  
U12128-1|AAB60339.1| 2490|Homo sapiens protein tyrosine phosphat...    31   5.0  
L34583-1|AAC41755.1|  610|Homo sapiens tyrosine phosphatase prot...    31   5.0  
D21211-1|BAA04752.1| 2294|Homo sapiens protein tyrosine phosphat...    31   5.0  
D21210-1|BAA04751.1| 2466|Homo sapiens protein tyrosine phosphat...    31   5.0  
D21209-1|BAA04750.1| 2485|Homo sapiens protein tyrosine phosphat...    31   5.0  
BC039610-1|AAH39610.1|  604|Homo sapiens PTPN13 protein protein.       31   5.0  
AF233323-1|AAF63474.1|  499|Homo sapiens Fas-associated phosphat...    31   5.0  
AC105413-1|AAY40972.1| 1305|Homo sapiens unknown protein.              31   5.0  
AB208904-1|BAD92141.1| 2434|Homo sapiens protein tyrosine phosph...    31   5.0  
BC010626-1|AAH10626.1|  513|Homo sapiens kinesin family member 1...    30   6.7  
AL137850-6|CAI15901.1|  646|Homo sapiens kinesin family member 1...    30   6.7  
AL137850-5|CAI15900.1|  513|Homo sapiens kinesin family member 1...    30   6.7  
X58430-1|CAB86198.1|  496|Homo sapiens homeobox protein protein.       30   8.8  

>BC071562-1|AAH71562.2| 1235|Homo sapiens NOTCH2 protein protein.
          Length = 1235

 Score = 31.5 bits (68), Expect = 2.9
 Identities = 21/69 (30%), Positives = 28/69 (40%), Gaps = 4/69 (5%)
 Frame = +1

Query: 367 VCTAFCTDGYTLGGCPA----CASQRSSPVAIAGRILNTSEGWQAWCNVPVRQGHGGAAC 534
           +CT  C  GY    C      CA   S+P   AG+ +NT   +   C     +G+ G  C
Sbjct: 400 ICT--CPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCEC----LKGYAGPRC 453

Query: 535 NCDSNTISS 561
             D N   S
Sbjct: 454 EMDINECHS 462


>AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2
           (Drosophila) protein.
          Length = 2471

 Score = 31.5 bits (68), Expect = 2.9
 Identities = 21/69 (30%), Positives = 28/69 (40%), Gaps = 4/69 (5%)
 Frame = +1

Query: 367 VCTAFCTDGYTLGGCPA----CASQRSSPVAIAGRILNTSEGWQAWCNVPVRQGHGGAAC 534
           +CT  C  GY    C      CA   S+P   AG+ +NT   +   C     +G+ G  C
Sbjct: 400 ICT--CPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCEC----LKGYAGPRC 453

Query: 535 NCDSNTISS 561
             D N   S
Sbjct: 454 EMDINECHS 462


>AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2
           (Drosophila) protein.
          Length = 2471

 Score = 31.5 bits (68), Expect = 2.9
 Identities = 21/69 (30%), Positives = 28/69 (40%), Gaps = 4/69 (5%)
 Frame = +1

Query: 367 VCTAFCTDGYTLGGCPA----CASQRSSPVAIAGRILNTSEGWQAWCNVPVRQGHGGAAC 534
           +CT  C  GY    C      CA   S+P   AG+ +NT   +   C     +G+ G  C
Sbjct: 400 ICT--CPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCEC----LKGYAGPRC 453

Query: 535 NCDSNTISS 561
             D N   S
Sbjct: 454 EMDINECHS 462


>AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2
           (Drosophila) protein.
          Length = 2471

 Score = 31.5 bits (68), Expect = 2.9
 Identities = 21/69 (30%), Positives = 28/69 (40%), Gaps = 4/69 (5%)
 Frame = +1

Query: 367 VCTAFCTDGYTLGGCPA----CASQRSSPVAIAGRILNTSEGWQAWCNVPVRQGHGGAAC 534
           +CT  C  GY    C      CA   S+P   AG+ +NT   +   C     +G+ G  C
Sbjct: 400 ICT--CPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCEC----LKGYAGPRC 453

Query: 535 NCDSNTISS 561
             D N   S
Sbjct: 454 EMDINECHS 462


>AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein.
          Length = 2471

 Score = 31.5 bits (68), Expect = 2.9
 Identities = 21/69 (30%), Positives = 28/69 (40%), Gaps = 4/69 (5%)
 Frame = +1

Query: 367 VCTAFCTDGYTLGGCPA----CASQRSSPVAIAGRILNTSEGWQAWCNVPVRQGHGGAAC 534
           +CT  C  GY    C      CA   S+P   AG+ +NT   +   C     +G+ G  C
Sbjct: 400 ICT--CPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCEC----LKGYAGPRC 453

Query: 535 NCDSNTISS 561
             D N   S
Sbjct: 454 EMDINECHS 462


>AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein.
          Length = 2471

 Score = 31.5 bits (68), Expect = 2.9
 Identities = 21/69 (30%), Positives = 28/69 (40%), Gaps = 4/69 (5%)
 Frame = +1

Query: 367 VCTAFCTDGYTLGGCPA----CASQRSSPVAIAGRILNTSEGWQAWCNVPVRQGHGGAAC 534
           +CT  C  GY    C      CA   S+P   AG+ +NT   +   C     +G+ G  C
Sbjct: 400 ICT--CPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCEC----LKGYAGPRC 453

Query: 535 NCDSNTISS 561
             D N   S
Sbjct: 454 EMDINECHS 462


>X52541-1|CAA36777.1|  543|Homo sapiens protein ( Human mRNA for
           early growth response protein 1 (hEGR1). ).
          Length = 543

 Score = 31.1 bits (67), Expect = 3.8
 Identities = 17/49 (34%), Positives = 26/49 (53%), Gaps = 2/49 (4%)
 Frame = +2

Query: 413 QPVPPNGAALWPSPVGS--STLLRVGRPGATFQCARGMAGPRATAIRTP 553
           +P P +G  LWP P+ S  S L+ +  P A+   A   A   A+A ++P
Sbjct: 140 EPAPNSGNTLWPEPLFSLVSGLVSMTNPPASSSSAPSPAASSASASQSP 188


>M62829-1|AAA35815.1|  543|Homo sapiens ETR103 protein.
          Length = 543

 Score = 31.1 bits (67), Expect = 3.8
 Identities = 17/49 (34%), Positives = 26/49 (53%), Gaps = 2/49 (4%)
 Frame = +2

Query: 413 QPVPPNGAALWPSPVGS--STLLRVGRPGATFQCARGMAGPRATAIRTP 553
           +P P +G  LWP P+ S  S L+ +  P A+   A   A   A+A ++P
Sbjct: 140 EPAPNSGNTLWPEPLFSLVSGLVSMTNPPASSSSAPSPAASSASASQSP 188


>BC073983-1|AAH73983.1|  543|Homo sapiens early growth response 1
           protein.
          Length = 543

 Score = 31.1 bits (67), Expect = 3.8
 Identities = 17/49 (34%), Positives = 26/49 (53%), Gaps = 2/49 (4%)
 Frame = +2

Query: 413 QPVPPNGAALWPSPVGS--STLLRVGRPGATFQCARGMAGPRATAIRTP 553
           +P P +G  LWP P+ S  S L+ +  P A+   A   A   A+A ++P
Sbjct: 140 EPAPNSGNTLWPEPLFSLVSGLVSMTNPPASSSSAPSPAASSASASQSP 188


>AJ243425-1|CAB46678.1|  543|Homo sapiens early growth response
           protein 1 protein.
          Length = 543

 Score = 31.1 bits (67), Expect = 3.8
 Identities = 17/49 (34%), Positives = 26/49 (53%), Gaps = 2/49 (4%)
 Frame = +2

Query: 413 QPVPPNGAALWPSPVGS--STLLRVGRPGATFQCARGMAGPRATAIRTP 553
           +P P +G  LWP P+ S  S L+ +  P A+   A   A   A+A ++P
Sbjct: 140 EPAPNSGNTLWPEPLFSLVSGLVSMTNPPASSSSAPSPAASSASASQSP 188


>X80289-1|CAA56563.1| 2466|Homo sapiens protein-tyrosine-phosphatase
            protein.
          Length = 2466

 Score = 30.7 bits (66), Expect = 5.0
 Identities = 19/59 (32%), Positives = 27/59 (45%)
 Frame = -3

Query: 407  PPSVYPSVQNAVQTALQSTAWSSSGCTQLHNG*PKLLPQSAGHTENRGSPYSRQCCWFP 231
            PP V P +  A+ T LQS A      ++  +  P  + QS    EN  S  S++ C  P
Sbjct: 1570 PPGVLPEIDTALLTPLQSPAQVLPNSSK-DSSQPSCVEQSTSSDENEMSDKSKKQCKSP 1627


>X79676-1|CAA56124.1| 1267|Homo sapiens tyrosine phosphatase
           protein.
          Length = 1267

 Score = 30.7 bits (66), Expect = 5.0
 Identities = 19/59 (32%), Positives = 27/59 (45%)
 Frame = -3

Query: 407 PPSVYPSVQNAVQTALQSTAWSSSGCTQLHNG*PKLLPQSAGHTENRGSPYSRQCCWFP 231
           PP V P +  A+ T LQS A      ++  +  P  + QS    EN  S  S++ C  P
Sbjct: 373 PPGVLPEIDTALLTPLQSPAQVLPNSSK-DSSQPSCVEQSTSSDENEMSDKSKKQCKSP 430


>U12128-1|AAB60339.1| 2490|Homo sapiens protein tyrosine phosphatase
            1E protein.
          Length = 2490

 Score = 30.7 bits (66), Expect = 5.0
 Identities = 19/59 (32%), Positives = 27/59 (45%)
 Frame = -3

Query: 407  PPSVYPSVQNAVQTALQSTAWSSSGCTQLHNG*PKLLPQSAGHTENRGSPYSRQCCWFP 231
            PP V P +  A+ T LQS A      ++  +  P  + QS    EN  S  S++ C  P
Sbjct: 1594 PPGVLPEIDTALLTPLQSPAQVLPNSSK-DSSQPSCVEQSTSSDENEMSDKSKKQCKSP 1651


>L34583-1|AAC41755.1|  610|Homo sapiens tyrosine phosphatase
           protein.
          Length = 610

 Score = 30.7 bits (66), Expect = 5.0
 Identities = 19/59 (32%), Positives = 27/59 (45%)
 Frame = -3

Query: 407 PPSVYPSVQNAVQTALQSTAWSSSGCTQLHNG*PKLLPQSAGHTENRGSPYSRQCCWFP 231
           PP V P +  A+ T LQS A      ++  +  P  + QS    EN  S  S++ C  P
Sbjct: 316 PPGVLPEIDTALLTPLQSPAQVLPNSSK-DSSQPSCVEQSTSSDENEMSDKSKKQCKSP 373


>D21211-1|BAA04752.1| 2294|Homo sapiens protein tyrosine phosphatase
            type 3 protein.
          Length = 2294

 Score = 30.7 bits (66), Expect = 5.0
 Identities = 19/59 (32%), Positives = 27/59 (45%)
 Frame = -3

Query: 407  PPSVYPSVQNAVQTALQSTAWSSSGCTQLHNG*PKLLPQSAGHTENRGSPYSRQCCWFP 231
            PP V P +  A+ T LQS A      ++  +  P  + QS    EN  S  S++ C  P
Sbjct: 1398 PPGVLPEIDTALLTPLQSPAQVLPNSSK-DSSQPSCVEQSTSSDENEMSDKSKKQCKSP 1455


>D21210-1|BAA04751.1| 2466|Homo sapiens protein tyrosine phosphatase
            type 2 protein.
          Length = 2466

 Score = 30.7 bits (66), Expect = 5.0
 Identities = 19/59 (32%), Positives = 27/59 (45%)
 Frame = -3

Query: 407  PPSVYPSVQNAVQTALQSTAWSSSGCTQLHNG*PKLLPQSAGHTENRGSPYSRQCCWFP 231
            PP V P +  A+ T LQS A      ++  +  P  + QS    EN  S  S++ C  P
Sbjct: 1570 PPGVLPEIDTALLTPLQSPAQVLPNSSK-DSSQPSCVEQSTSSDENEMSDKSKKQCKSP 1627


>D21209-1|BAA04750.1| 2485|Homo sapiens protein tyrosine phosphatase
            type 1 protein.
          Length = 2485

 Score = 30.7 bits (66), Expect = 5.0
 Identities = 19/59 (32%), Positives = 27/59 (45%)
 Frame = -3

Query: 407  PPSVYPSVQNAVQTALQSTAWSSSGCTQLHNG*PKLLPQSAGHTENRGSPYSRQCCWFP 231
            PP V P +  A+ T LQS A      ++  +  P  + QS    EN  S  S++ C  P
Sbjct: 1589 PPGVLPEIDTALLTPLQSPAQVLPNSSK-DSSQPSCVEQSTSSDENEMSDKSKKQCKSP 1646


>BC039610-1|AAH39610.1|  604|Homo sapiens PTPN13 protein protein.
          Length = 604

 Score = 30.7 bits (66), Expect = 5.0
 Identities = 19/59 (32%), Positives = 27/59 (45%)
 Frame = -3

Query: 407 PPSVYPSVQNAVQTALQSTAWSSSGCTQLHNG*PKLLPQSAGHTENRGSPYSRQCCWFP 231
           PP V P +  A+ T LQS A      ++  +  P  + QS    EN  S  S++ C  P
Sbjct: 267 PPGVLPEIDTALLTPLQSPAQVLPNSSK-DSSQPSCVEQSTSSDENEMSDKSKKQCKSP 324


>AF233323-1|AAF63474.1|  499|Homo sapiens Fas-associated
           phosphatase-1 protein.
          Length = 499

 Score = 30.7 bits (66), Expect = 5.0
 Identities = 19/59 (32%), Positives = 27/59 (45%)
 Frame = -3

Query: 407 PPSVYPSVQNAVQTALQSTAWSSSGCTQLHNG*PKLLPQSAGHTENRGSPYSRQCCWFP 231
           PP V P +  A+ T LQS A      ++  +  P  + QS    EN  S  S++ C  P
Sbjct: 267 PPGVLPEIDTALLTPLQSPAQVLPNSSK-DSSQPSCVEQSTSSDENEMSDKSKKQCKSP 324


>AC105413-1|AAY40972.1| 1305|Homo sapiens unknown protein.
          Length = 1305

 Score = 30.7 bits (66), Expect = 5.0
 Identities = 19/59 (32%), Positives = 27/59 (45%)
 Frame = -3

Query: 407 PPSVYPSVQNAVQTALQSTAWSSSGCTQLHNG*PKLLPQSAGHTENRGSPYSRQCCWFP 231
           PP V P +  A+ T LQS A      ++  +  P  + QS    EN  S  S++ C  P
Sbjct: 409 PPGVLPEIDTALLTPLQSPAQVLPNSSK-DSSQPSCVEQSTSSDENEMSDKSKKQCKSP 466


>AB208904-1|BAD92141.1| 2434|Homo sapiens protein tyrosine
            phosphatase, non-receptor type 13 isoform 2 variant
            protein.
          Length = 2434

 Score = 30.7 bits (66), Expect = 5.0
 Identities = 19/59 (32%), Positives = 27/59 (45%)
 Frame = -3

Query: 407  PPSVYPSVQNAVQTALQSTAWSSSGCTQLHNG*PKLLPQSAGHTENRGSPYSRQCCWFP 231
            PP V P +  A+ T LQS A      ++  +  P  + QS    EN  S  S++ C  P
Sbjct: 1538 PPGVLPEIDTALLTPLQSPAQVLPNSSK-DSSQPSCVKQSTSSDENEMSDKSKKQCKSP 1595


>BC010626-1|AAH10626.1|  513|Homo sapiens kinesin family member 12
           protein.
          Length = 513

 Score = 30.3 bits (65), Expect = 6.7
 Identities = 15/37 (40%), Positives = 16/37 (43%)
 Frame = -2

Query: 519 MPLAHWNVAPGLPTLRSVEDPTGDGHRAAPLGGTGWA 409
           +PLAHW   PG   L  V DP   G R        WA
Sbjct: 378 VPLAHWACLPGEHHLPQVLDPEASGGRPPSARPPPWA 414


>AL137850-6|CAI15901.1|  646|Homo sapiens kinesin family member 12
           protein.
          Length = 646

 Score = 30.3 bits (65), Expect = 6.7
 Identities = 15/37 (40%), Positives = 16/37 (43%)
 Frame = -2

Query: 519 MPLAHWNVAPGLPTLRSVEDPTGDGHRAAPLGGTGWA 409
           +PLAHW   PG   L  V DP   G R        WA
Sbjct: 511 VPLAHWACLPGEHHLPQVLDPEASGGRPPSARPPPWA 547


>AL137850-5|CAI15900.1|  513|Homo sapiens kinesin family member 12
           protein.
          Length = 513

 Score = 30.3 bits (65), Expect = 6.7
 Identities = 15/37 (40%), Positives = 16/37 (43%)
 Frame = -2

Query: 519 MPLAHWNVAPGLPTLRSVEDPTGDGHRAAPLGGTGWA 409
           +PLAHW   PG   L  V DP   G R        WA
Sbjct: 378 VPLAHWACLPGEHHLPQVLDPEASGGRPPSARPPPWA 414


>X58430-1|CAB86198.1|  496|Homo sapiens homeobox protein protein.
          Length = 496

 Score = 29.9 bits (64), Expect = 8.8
 Identities = 15/31 (48%), Positives = 19/31 (61%), Gaps = 1/31 (3%)
 Frame = +2

Query: 401 WEVAQPVPPNGAALWPSPVG-SSTLLRVGRP 490
           W  +   PP+GAA W  P G S+ LLR+ RP
Sbjct: 274 WLPSAGPPPDGAAPWAPPAGCSAWLLRLLRP 304


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 107,592,805
Number of Sequences: 237096
Number of extensions: 2667588
Number of successful extensions: 8363
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 7577
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8359
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7783251346
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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