Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= NV060123.seq
(692 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P40320 Cluster: S-adenosylmethionine synthetase; n=19; ... 180 3e-44
UniRef50_Q00266 Cluster: S-adenosylmethionine synthetase isoform... 161 2e-38
UniRef50_Q8MU02 Cluster: Putative S-adenosylmethionine synthetas... 137 3e-31
UniRef50_P19358 Cluster: S-adenosylmethionine synthetase 2; n=65... 137 3e-31
UniRef50_Q29NR2 Cluster: GA15421-PA; n=3; Bilateria|Rep: GA15421... 134 2e-30
UniRef50_Q837P9 Cluster: S-adenosylmethionine synthetase; n=45; ... 99 9e-20
UniRef50_P0A820 Cluster: S-adenosylmethionine synthetase; n=23; ... 98 2e-19
UniRef50_A7NSM8 Cluster: Chromosome chr18 scaffold_1, whole geno... 97 5e-19
UniRef50_Q9K7Q9 Cluster: S-adenosylmethionine synthetase; n=65; ... 95 1e-18
UniRef50_P72871 Cluster: S-adenosylmethionine synthetase; n=119;... 93 8e-18
UniRef50_A7APP7 Cluster: S-adenosylmethionine synthetase, putati... 91 2e-17
UniRef50_Q661P3 Cluster: S-adenosylmethionine synthetase; n=3; B... 80 6e-14
UniRef50_Q650L4 Cluster: S-adenosylmethionine synthetase; n=19; ... 80 6e-14
UniRef50_A4QEH8 Cluster: Putative uncharacterized protein; n=1; ... 76 7e-13
UniRef50_Q7QWJ4 Cluster: S-adenosylmethionine synthetase; n=1; G... 71 3e-11
UniRef50_Q2U8T6 Cluster: S-adenosylmethionine synthetase; n=2; A... 71 3e-11
UniRef50_Q4A5F4 Cluster: S-adenosylmethionine synthetase; n=4; B... 68 2e-10
UniRef50_Q1GND0 Cluster: S-adenosylmethionine synthetase; n=29; ... 62 2e-08
UniRef50_Q6KHY1 Cluster: S-adenosylmethionine synthetase; n=7; M... 60 7e-08
UniRef50_Q2LSR0 Cluster: S-adenosylmethionine synthetase; n=1; S... 59 9e-08
UniRef50_Q5FGR4 Cluster: S-adenosylmethionine synthetase; n=13; ... 58 2e-07
UniRef50_Q7NB16 Cluster: S-adenosylmethionine synthetase; n=2; M... 58 3e-07
UniRef50_Q60BL6 Cluster: S-adenosylmethionine synthetase; n=6; B... 57 5e-07
UniRef50_A6BGC6 Cluster: S-adenosylmethionine synthetase; n=1; D... 56 6e-07
UniRef50_O09486 Cluster: S-adenosylmethionine synthetase; n=1; A... 56 8e-07
UniRef50_UPI00015BD1C2 Cluster: UPI00015BD1C2 related cluster; n... 55 2e-06
UniRef50_A6QA94 Cluster: S-adenosylmethionine synthetase; n=20; ... 55 2e-06
UniRef50_Q6SZ22 Cluster: S-adenosylmethionine synthetase; n=4; S... 52 1e-05
UniRef50_Q2GDS4 Cluster: S-adenosylmethionine synthetase; n=1; N... 52 1e-05
UniRef50_P78003 Cluster: S-adenosylmethionine synthetase; n=4; M... 51 3e-05
UniRef50_Q7R6Z1 Cluster: Putative uncharacterized protein PY0779... 47 4e-04
UniRef50_Q1VNA9 Cluster: S-adenosylmethionine synthetase; n=1; P... 46 9e-04
UniRef50_Q6A7D8 Cluster: S-adenosylmethionine synthetase; n=11; ... 44 0.003
UniRef50_Q95QX7 Cluster: Putative uncharacterized protein; n=1; ... 44 0.003
UniRef50_A6PKG8 Cluster: Methionine adenosyltransferase precurso... 43 0.006
UniRef50_Q027Y1 Cluster: Methionine adenosyltransferase; n=1; So... 38 0.31
UniRef50_A4HUR1 Cluster: Chromosome 10; n=3; Leishmania|Rep: Chr... 37 0.41
UniRef50_UPI0000F1FBF8 Cluster: PREDICTED: hypothetical protein;... 36 0.71
UniRef50_A4DEX8 Cluster: Putative uncharacterized protein; n=1; ... 36 1.2
UniRef50_Q8FXU7 Cluster: Protease, putative; n=6; Brucellaceae|R... 35 1.6
UniRef50_A1A5Z7 Cluster: Zgc:158441; n=7; Deuterostomia|Rep: Zgc... 34 2.9
UniRef50_A4A0G4 Cluster: DNA-binding protein; n=1; Blastopirellu... 34 2.9
UniRef50_A6RT45 Cluster: Putative uncharacterized protein; n=2; ... 34 2.9
UniRef50_UPI00006A2011 Cluster: Tumor necrosis factor receptor s... 34 3.8
UniRef50_Q15TP8 Cluster: Adenosine deaminase; n=2; Gammaproteoba... 34 3.8
UniRef50_P37937 Cluster: Mating-type protein A-alpha Z3; n=1; Sc... 33 5.0
UniRef50_Q4T9B3 Cluster: Chromosome undetermined SCAF7602, whole... 33 6.6
UniRef50_A3ES79 Cluster: Transposase; n=1; Leptospirillum sp. Gr... 33 6.6
UniRef50_A5AMB5 Cluster: Putative uncharacterized protein; n=1; ... 33 6.6
UniRef50_Q6CUT6 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 33 8.8
>UniRef50_P40320 Cluster: S-adenosylmethionine synthetase; n=19;
Eukaryota|Rep: S-adenosylmethionine synthetase -
Drosophila melanogaster (Fruit fly)
Length = 408
Score = 180 bits (438), Expect = 3e-44
Identities = 90/149 (60%), Positives = 107/149 (71%), Gaps = 1/149 (0%)
Frame = +1
Query: 244 KSCIETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQ 423
K ET+ KTGM+LLCGEITSKA VDYQKVVRETV+HIGYDDSSKGFD+KTC+V+LALDQ
Sbjct: 64 KVACETVAKTGMILLCGEITSKAVVDYQKVVRETVQHIGYDDSSKGFDFKTCNVLLALDQ 123
Query: 424 QSPNIAAGVHENRNDEEVGAGDQGLMFGLQQMRQKNACR*L*CLHTNSI-RKLQSFRRNG 600
QSP IAAGVH NR +EE+GAGDQG+MFG + C L + + + K+ RR+
Sbjct: 124 QSPEIAAGVHVNRAEEEIGAGDQGIMFG-YATDETEECMPLTVVLAHKLNEKIAELRRSD 182
Query: 601 RFWWARPDSKNTGLLANMYLPGGATVPHR 687
FWWARPDSK T + G+ VP R
Sbjct: 183 VFWWARPDSK-TQVTCEYLFNQGSAVPKR 210
Score = 105 bits (251), Expect = 1e-21
Identities = 47/56 (83%), Positives = 51/56 (91%)
Frame = +2
Query: 86 NGXAKTNGHSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVA 253
NG +NG+SYDMEDG+ FLFTSESVGEGHPDKMCDQISDAILDAHL QDP+AKVA
Sbjct: 11 NGCNGSNGNSYDMEDGATFLFTSESVGEGHPDKMCDQISDAILDAHLKQDPNAKVA 66
>UniRef50_Q00266 Cluster: S-adenosylmethionine synthetase isoform
type-1; n=171; cellular organisms|Rep:
S-adenosylmethionine synthetase isoform type-1 - Homo
sapiens (Human)
Length = 395
Score = 161 bits (390), Expect = 2e-38
Identities = 81/149 (54%), Positives = 104/149 (69%), Gaps = 1/149 (0%)
Frame = +1
Query: 244 KSCIETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQ 423
K ET+ KTGMVLLCGEITS A VDYQ+VVR+T+KHIGYDDS+KGFD+KTC+V++AL+Q
Sbjct: 53 KVACETVCKTGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQ 112
Query: 424 QSPNIAAGVHENRNDEEVGAGDQGLMFGLQQMRQKNACR*L*CLHTNSIR-KLQSFRRNG 600
QSP+IA VH +RN+E+VGAGDQGLMFG + C L + + + ++ RR+G
Sbjct: 113 QSPDIAQCVHLDRNEEDVGAGDQGLMFG-YATDETEECMPLTIILAHKLNARMADLRRSG 171
Query: 601 RFWWARPDSKNTGLLANMYLPGGATVPHR 687
W RPDSK T + GA +P R
Sbjct: 172 LLPWLRPDSK-TQVTVQYMQDNGAVIPVR 199
Score = 79.8 bits (188), Expect = 6e-14
Identities = 35/46 (76%), Positives = 42/46 (91%)
Frame = +2
Query: 116 YDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVA 253
+ + +G VF+FTSESVGEGHPDK+CDQISDA+LDAHL QDP+AKVA
Sbjct: 11 HSLSEG-VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVA 55
>UniRef50_Q8MU02 Cluster: Putative S-adenosylmethionine synthetase;
n=1; Heterodera glycines|Rep: Putative
S-adenosylmethionine synthetase - Heterodera glycines
(Soybean cyst nematode worm)
Length = 211
Score = 137 bits (331), Expect = 3e-31
Identities = 61/87 (70%), Positives = 74/87 (85%)
Frame = +1
Query: 244 KSCIETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQ 423
K E +TKTGMVL+CGE TS A VDYQ VVRET+K IGYDDSSKGF+YKTC+V++AL++
Sbjct: 90 KVACEVVTKTGMVLVCGETTSSATVDYQSVVRETIKKIGYDDSSKGFNYKTCNVLVALEK 149
Query: 424 QSPNIAAGVHENRNDEEVGAGDQGLMF 504
QSP IAAGVHE++ E+VGA DQG+MF
Sbjct: 150 QSPEIAAGVHEDKEPEDVGARDQGIMF 176
Score = 76.6 bits (180), Expect = 5e-13
Identities = 36/43 (83%), Positives = 36/43 (83%)
Frame = +2
Query: 125 EDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVA 253
E FLFTSESVGEGHPDKMCDQISDAILDAHL DP AKVA
Sbjct: 50 EQVGTFLFTSESVGEGHPDKMCDQISDAILDAHLALDPAAKVA 92
Score = 38.7 bits (86), Expect = 0.13
Identities = 17/36 (47%), Positives = 25/36 (69%)
Frame = +3
Query: 483 RRPGLDVRFATDETEECMPLTVVLAHKLNQKIAELQ 590
R G+ + +DE+ E MPLT+VL+HKLN K +L+
Sbjct: 170 RDQGIMFXYPSDESPEAMPLTLVLSHKLNAKYHQLR 205
>UniRef50_P19358 Cluster: S-adenosylmethionine synthetase 2; n=659;
cellular organisms|Rep: S-adenosylmethionine synthetase
2 - Saccharomyces cerevisiae (Baker's yeast)
Length = 384
Score = 137 bits (331), Expect = 3e-31
Identities = 68/148 (45%), Positives = 94/148 (63%)
Frame = +1
Query: 244 KSCIETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQ 423
K ET KTGM+++ GEIT+KA +DYQ++VR+T+K IGYDDS+KGFDYKTC+V++A++Q
Sbjct: 42 KVACETAAKTGMIMVFGEITTKARLDYQQIVRDTIKKIGYDDSAKGFDYKTCNVLVAIEQ 101
Query: 424 QSPNIAAGVHENRNDEEVGAGDQGLMFGLQQMRQKNACR*L*CLHTNSIRKLQSFRRNGR 603
QSP+IA G+H ++ E++GAGDQG+MFG L + RR+G
Sbjct: 102 QSPDIAQGLHYEKSLEDLGAGDQGIMFGYATDETPEGLPLTILLAHKLNMAMADARRDGS 161
Query: 604 FWWARPDSKNTGLLANMYLPGGATVPHR 687
W RPD+K T + G VP R
Sbjct: 162 LPWLRPDTK-TQVTVEYEDDNGRWVPKR 188
Score = 72.9 bits (171), Expect = 7e-12
Identities = 33/44 (75%), Positives = 36/44 (81%)
Frame = +2
Query: 122 MEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVA 253
M FLFTSESVGEGHPDK+CDQ+SDAILDA L QDP +KVA
Sbjct: 1 MSKSKTFLFTSESVGEGHPDKICDQVSDAILDACLEQDPFSKVA 44
>UniRef50_Q29NR2 Cluster: GA15421-PA; n=3; Bilateria|Rep: GA15421-PA
- Drosophila pseudoobscura (Fruit fly)
Length = 200
Score = 134 bits (324), Expect = 2e-30
Identities = 60/83 (72%), Positives = 74/83 (89%)
Frame = +1
Query: 244 KSCIETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQ 423
K ET+ KTGM+LLCGEITSKA VDYQKVVRETV+HIGYDDSSKGFD+KT ++++A++Q
Sbjct: 64 KVACETVAKTGMILLCGEITSKAVVDYQKVVRETVQHIGYDDSSKGFDWKTLNLLVAIEQ 123
Query: 424 QSPNIAAGVHENRNDEEVGAGDQ 492
QSP+IA GVH NR +++VGAGDQ
Sbjct: 124 QSPDIANGVHINREEDDVGAGDQ 146
Score = 104 bits (250), Expect = 2e-21
Identities = 47/56 (83%), Positives = 50/56 (89%)
Frame = +2
Query: 86 NGXAKTNGHSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVA 253
NG +NG+SYDMEDG FLFTSESVGEGHPDKMCDQISDAILDAHL QDP+AKVA
Sbjct: 11 NGCNGSNGNSYDMEDGQTFLFTSESVGEGHPDKMCDQISDAILDAHLKQDPNAKVA 66
>UniRef50_Q837P9 Cluster: S-adenosylmethionine synthetase; n=45;
cellular organisms|Rep: S-adenosylmethionine synthetase
- Enterococcus faecalis (Streptococcus faecalis)
Length = 394
Score = 99.1 bits (236), Expect = 9e-20
Identities = 59/137 (43%), Positives = 83/137 (60%), Gaps = 6/137 (4%)
Frame = +1
Query: 241 RKSCIETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALD 420
R +C ET TG+VL+ GEI++ A VD QK+VR+TVK IGY + GFD +T +V++A+D
Sbjct: 40 RVAC-ETSVTTGLVLVFGEISTTAYVDIQKIVRQTVKDIGYTRAKYGFDGETVAVLVAID 98
Query: 421 QQSPNIAAGVH---ENRNDEE---VGAGDQGLMFGLQQMRQKNACR*L*CLHTNSIRKLQ 582
+QSP+IA GV E R+ +E +GAGDQGLMFG L +R+L
Sbjct: 99 EQSPDIAQGVDAALEVRDQDEKDDIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRLA 158
Query: 583 SFRRNGRFWWARPDSKN 633
R+ + RPD+K+
Sbjct: 159 ELRKEKVLPYLRPDAKS 175
Score = 61.3 bits (142), Expect = 2e-08
Identities = 28/37 (75%), Positives = 32/37 (86%)
Frame = +2
Query: 143 LFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVA 253
LFTSESV EGHPDK+ DQ+SDAILDA L +DP A+VA
Sbjct: 6 LFTSESVSEGHPDKVADQVSDAILDAILEKDPMARVA 42
>UniRef50_P0A820 Cluster: S-adenosylmethionine synthetase; n=23;
Proteobacteria|Rep: S-adenosylmethionine synthetase -
Shigella flexneri
Length = 384
Score = 97.9 bits (233), Expect = 2e-19
Identities = 55/131 (41%), Positives = 76/131 (58%)
Frame = +1
Query: 241 RKSCIETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALD 420
R +C ET KTGMVL+ GEIT+ A VD +++ R TV+ IGY S GFD +C+V+ A+
Sbjct: 39 RVAC-ETYVKTGMVLVGGEITTSAWVDIEEITRNTVREIGYVHSDMGFDANSCAVLSAIG 97
Query: 421 QQSPNIAAGVHENRNDEEVGAGDQGLMFGLQQMRQKNACR*L*CLHTNSIRKLQSFRRNG 600
+QSP+I GV + + E GAGDQGLMFG +++ R+NG
Sbjct: 98 KQSPDINQGV-DRADPLEQGAGDQGLMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNG 156
Query: 601 RFWWARPDSKN 633
W RPD+K+
Sbjct: 157 TLPWLRPDAKS 167
Score = 64.1 bits (149), Expect = 3e-09
Identities = 30/43 (69%), Positives = 35/43 (81%)
Frame = +2
Query: 143 LFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVALKP*LK 271
LFTSESV EGHPDK+ DQISDA+LDA L QDP A+VA + +K
Sbjct: 5 LFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVK 47
>UniRef50_A7NSM8 Cluster: Chromosome chr18 scaffold_1, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr18 scaffold_1, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 509
Score = 96.7 bits (230), Expect = 5e-19
Identities = 57/146 (39%), Positives = 75/146 (51%)
Frame = +1
Query: 244 KSCIETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQ 423
K ET TKT MV++ GEIT+KAN+DY+K+VR+T + IG+ GFD C V++ + Q
Sbjct: 277 KVACETCTKTDMVMIFGEITTKANIDYEKIVRDTCRTIGFVFYDVGFDVDNCKVLVNIGQ 336
Query: 424 QSPNIAAGVHENRNDEEVGAGDQGLMFGLQQMRQKNACR*L*CLHTNSIRKLQSFRRNGR 603
QSPNI V + + AGDQG MFG L T +L R+N
Sbjct: 337 QSPNITQDV------QGISAGDQGHMFGYATNETPKLMPLSHVLSTKLSARLTEVRKNET 390
Query: 604 FWWARPDSKNTGLLANMYLPGGATVP 681
W RPD K T + + GA P
Sbjct: 391 CSWLRPDGK-TQVTVEYHDENGAMAP 415
Score = 41.9 bits (94), Expect = 0.014
Identities = 20/37 (54%), Positives = 25/37 (67%)
Frame = +2
Query: 143 LFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVA 253
L+ E V GH ++ ISDA+LDA L QDPD+KVA
Sbjct: 243 LYYMEDVSIGHVHQIQSDISDAVLDACLTQDPDSKVA 279
>UniRef50_Q9K7Q9 Cluster: S-adenosylmethionine synthetase; n=65;
cellular organisms|Rep: S-adenosylmethionine synthetase
- Bacillus halodurans
Length = 399
Score = 95.5 bits (227), Expect = 1e-18
Identities = 56/145 (38%), Positives = 80/145 (55%), Gaps = 10/145 (6%)
Frame = +1
Query: 226 ESGSGRKSCIETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSV 405
E + R +C ET TG+VL+ GEIT+ VD KVVR+T+++IGY + GFD +TC+V
Sbjct: 38 EDPNARVAC-ETSVTTGLVLVAGEITTSTYVDIPKVVRDTIRNIGYTRAKYGFDSETCAV 96
Query: 406 MLALDQQSPNIAAGVHE----------NRNDEEVGAGDQGLMFGLQQMRQKNACR*L*CL 555
+ ++D+QSP+IA GV++ + E +GAGDQGLMFG L
Sbjct: 97 LTSIDEQSPDIAQGVNQALEAREGQMTDAEIEAIGAGDQGLMFGYANNETPELMPLPISL 156
Query: 556 HTNSIRKLQSFRRNGRFWWARPDSK 630
R+L R+ + RPD K
Sbjct: 157 SHKLARRLSEARKGEILPYLRPDGK 181
Score = 63.3 bits (147), Expect = 5e-09
Identities = 28/37 (75%), Positives = 33/37 (89%)
Frame = +2
Query: 143 LFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVA 253
LFTSESV EGHPDK+CDQISD+ILD L +DP+A+VA
Sbjct: 9 LFTSESVTEGHPDKICDQISDSILDEILKEDPNARVA 45
>UniRef50_P72871 Cluster: S-adenosylmethionine synthetase; n=119;
Bacteria|Rep: S-adenosylmethionine synthetase -
Synechocystis sp. (strain PCC 6803)
Length = 426
Score = 92.7 bits (220), Expect = 8e-18
Identities = 49/134 (36%), Positives = 79/134 (58%), Gaps = 9/134 (6%)
Frame = +1
Query: 256 ETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPN 435
ET+ TG+ L+ GEITS+A++++ +++R+ + IGY ++ G+ +C+VMLA+D+QSP+
Sbjct: 50 ETVVNTGLTLVTGEITSQAHINFVELIRQKIAEIGYTNADNGYSANSCAVMLAIDEQSPD 109
Query: 436 IAAGV-------HENRNDE--EVGAGDQGLMFGLQQMRQKNACR*L*CLHTNSIRKLQSF 588
I+ GV H +DE ++GAGDQGLMFG L +L
Sbjct: 110 ISQGVTAAQEQRHALSDDELDKIGAGDQGLMFGYACNETPELMPLPISLAHRIALRLSEV 169
Query: 589 RRNGRFWWARPDSK 630
R++G+ + RPD K
Sbjct: 170 RKSGQLAYLRPDGK 183
Score = 63.3 bits (147), Expect = 5e-09
Identities = 28/38 (73%), Positives = 33/38 (86%)
Frame = +2
Query: 140 FLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVA 253
+LFTSESV EGHPDK+CDQISD ILDA L DP+++VA
Sbjct: 11 YLFTSESVTEGHPDKVCDQISDTILDALLTLDPNSRVA 48
>UniRef50_A7APP7 Cluster: S-adenosylmethionine synthetase, putative;
n=1; Babesia bovis|Rep: S-adenosylmethionine synthetase,
putative - Babesia bovis
Length = 416
Score = 91.1 bits (216), Expect = 2e-17
Identities = 54/148 (36%), Positives = 71/148 (47%)
Frame = +1
Query: 244 KSCIETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQ 423
K E +V++ GEIT+ A VDYQ VVR+ + IGY + GFD T +M+ L Q
Sbjct: 49 KVACEVCAIKNLVMVFGEITTNAVVDYQAVVRQVLTDIGYTSNELGFDASTVEIMVRLAQ 108
Query: 424 QSPNIAAGVHENRNDEEVGAGDQGLMFGLQQMRQKNACR*L*CLHTNSIRKLQSFRRNGR 603
Q+P IA+ VH R EE AGDQG+MFG L T ++L R+
Sbjct: 109 QAPEIASAVHLGRKLEETAAGDQGIMFGYASDETPELMPLSHALATRLGKRLTKVRKTKV 168
Query: 604 FWWARPDSKNTGLLANMYLPGGATVPHR 687
+ RPD K + P G P R
Sbjct: 169 MPYLRPDGKTQITVEYRVEPNGHLEPVR 196
Score = 73.3 bits (172), Expect = 5e-12
Identities = 34/45 (75%), Positives = 38/45 (84%)
Frame = +2
Query: 119 DMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVA 253
D D + FLFTSESV EGHPDK+CDQISDAILDA L QDP++KVA
Sbjct: 7 DTVDKNNFLFTSESVNEGHPDKICDQISDAILDACLRQDPESKVA 51
>UniRef50_Q661P3 Cluster: S-adenosylmethionine synthetase; n=3;
Borrelia burgdorferi group|Rep: S-adenosylmethionine
synthetase - Borrelia garinii
Length = 392
Score = 79.8 bits (188), Expect = 6e-14
Identities = 44/132 (33%), Positives = 72/132 (54%), Gaps = 2/132 (1%)
Frame = +1
Query: 244 KSCIETITKTGMVLLCGEITS--KANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLAL 417
K E I +V++ GEI S K +D +++ ++ +K IGY + G DYKT +V+ A+
Sbjct: 44 KVACEVIITQNLVVIAGEINSPVKKTLDIKEIAKKIIKDIGYTNIDYGLDYKTITVIDAI 103
Query: 418 DQQSPNIAAGVHENRNDEEVGAGDQGLMFGLQQMRQKNACR*L*CLHTNSIRKLQSFRRN 597
QS +I + + + +GAGDQG++FG KN L + ++K + R++
Sbjct: 104 GNQSQDIINAI-KKKGSNALGAGDQGIIFGYACDETKNFLPAPYELANSILKKASNLRKS 162
Query: 598 GRFWWARPDSKN 633
G W RPDSK+
Sbjct: 163 GAIEWLRPDSKS 174
Score = 52.8 bits (121), Expect = 8e-06
Identities = 25/35 (71%), Positives = 28/35 (80%)
Frame = +2
Query: 149 TSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVA 253
TSE+V EGHPDK+ DQISDAILD L D +AKVA
Sbjct: 12 TSEAVSEGHPDKIADQISDAILDEILKVDKNAKVA 46
>UniRef50_Q650L4 Cluster: S-adenosylmethionine synthetase; n=19;
cellular organisms|Rep: S-adenosylmethionine synthetase
- Bacteroides fragilis
Length = 430
Score = 79.8 bits (188), Expect = 6e-14
Identities = 48/134 (35%), Positives = 71/134 (52%), Gaps = 1/134 (0%)
Frame = +1
Query: 235 SGRKSCIETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLA 414
S + +C ET+ TG V+L GE+ + A VD Q + RE ++ IGY F+ +C V+ A
Sbjct: 36 SSKVAC-ETLVTTGQVVLAGEVKTGAYVDLQLIAREVIQKIGYTKGEYMFESNSCGVLSA 94
Query: 415 LDQQSPNIAAGVHENRNDEEVGAGDQGLMFGLQQMRQKNACR*L*CLHTNSIRKLQSFRR 594
+ +QS +I GV E + GAGDQG+MFG +N L + L RR
Sbjct: 95 IHEQSADINRGV-EREDPMNQGAGDQGMMFGYATNETENYMPLSLDLAHRILLVLADIRR 153
Query: 595 NGR-FWWARPDSKN 633
G+ + RPD+K+
Sbjct: 154 EGKEMTYLRPDAKS 167
Score = 60.1 bits (139), Expect = 5e-08
Identities = 27/38 (71%), Positives = 31/38 (81%)
Frame = +2
Query: 140 FLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVA 253
+LFTSESV EGHPDK+ DQISDA+LD L DP +KVA
Sbjct: 3 YLFTSESVSEGHPDKVADQISDAVLDKLLAYDPSSKVA 40
Score = 33.5 bits (73), Expect = 5.0
Identities = 17/54 (31%), Positives = 32/54 (59%)
Frame = +3
Query: 492 GLDVRFATDETEECMPLTVVLAHKLNQKIAELQAKWEILVGKTRFKKHRFTCEY 653
G+ +AT+ETE MPL++ LAH++ +A+++ + + + K + T EY
Sbjct: 120 GMMFGYATNETENYMPLSLDLAHRILLVLADIRREGKEMTYLRPDAKSQVTIEY 173
>UniRef50_A4QEH8 Cluster: Putative uncharacterized protein; n=1;
Corynebacterium glutamicum R|Rep: Putative
uncharacterized protein - Corynebacterium glutamicum
(strain R)
Length = 257
Score = 76.2 bits (179), Expect = 7e-13
Identities = 46/135 (34%), Positives = 68/135 (50%), Gaps = 9/135 (6%)
Frame = +1
Query: 253 IETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSP 432
+ET+ TG+V + GE+ + A V+ ++VR + IG++ S GFD +TC V +++ +QS
Sbjct: 46 VETVVTTGIVHVVGEVRTSAYVEIPQLVRNKLIEIGFNSSEVGFDGRTCGVSVSIGEQSQ 105
Query: 433 NIAAGVHEN---------RNDEEVGAGDQGLMFGLQQMRQKNACR*L*CLHTNSIRKLQS 585
IA GV + D+ GAGDQGLMFG + L R+L
Sbjct: 106 EIADGVDNSDEARTNGDVEEDDRAGAGDQGLMFGYATNETEEYMPLPIALAHRLSRRLTQ 165
Query: 586 FRRNGRFWWARPDSK 630
R+ G RPD K
Sbjct: 166 VRKEGIVPHLRPDGK 180
Score = 62.1 bits (144), Expect = 1e-08
Identities = 28/42 (66%), Positives = 35/42 (83%)
Frame = +2
Query: 134 SVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVALK 259
+V LFTSESV EGHPDK+CD ISD ILDA L +DP ++VA++
Sbjct: 6 AVRLFTSESVTEGHPDKICDAISDTILDALLEKDPQSRVAVE 47
>UniRef50_Q7QWJ4 Cluster: S-adenosylmethionine synthetase; n=1;
Giardia lamblia ATCC 50803|Rep: S-adenosylmethionine
synthetase - Giardia lamblia ATCC 50803
Length = 436
Score = 70.9 bits (166), Expect = 3e-11
Identities = 43/122 (35%), Positives = 64/122 (52%), Gaps = 1/122 (0%)
Frame = +1
Query: 268 KTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAG 447
K V L GEI++ A VDY ++VR+ ++ IGY+D D++T ++ + QSP+I
Sbjct: 53 KDNTVFLLGEISTTAVVDYNQIVRDVLREIGYEDEKTSCDWRTVEIINRISSQSPDIYQA 112
Query: 448 VHENRNDEEVGAGDQGLMFGLQQMRQKNACR*L*CLHTNSI-RKLQSFRRNGRFWWARPD 624
V +E+ AGDQG+M G K A L N + +L R+ G + RPD
Sbjct: 113 VF---RQDELCAGDQGIMIGYASQETK-ALMPATHLFANLLAMRLSRVRKTGVLPFLRPD 168
Query: 625 SK 630
SK
Sbjct: 169 SK 170
Score = 60.1 bits (139), Expect = 5e-08
Identities = 28/38 (73%), Positives = 30/38 (78%)
Frame = +2
Query: 140 FLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVA 253
FLFTSE V EGHPDK+CDQISD ILD L QD A+VA
Sbjct: 10 FLFTSEQVSEGHPDKICDQISDRILDTILAQDKIARVA 47
>UniRef50_Q2U8T6 Cluster: S-adenosylmethionine synthetase; n=2;
Ascomycota|Rep: S-adenosylmethionine synthetase -
Aspergillus oryzae
Length = 384
Score = 70.9 bits (166), Expect = 3e-11
Identities = 32/51 (62%), Positives = 42/51 (82%)
Frame = +2
Query: 122 MEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVALKP*LKP 274
M+ S FLFTSESVGEGHPDK+CDQ++DAILD L Q+P +KVA++ ++P
Sbjct: 1 MKSQSKFLFTSESVGEGHPDKICDQVADAILDECLKQNPLSKVAIEVAVRP 51
Score = 57.6 bits (133), Expect = 3e-07
Identities = 37/130 (28%), Positives = 59/130 (45%), Gaps = 1/130 (0%)
Frame = +1
Query: 244 KSCIETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQ 423
K IE + G+V++ G + +D +VR +K IGY + DY+TC VM ++
Sbjct: 42 KVAIEVAVRPGLVIVFGVVHFIPQLDIDAIVRFVLKDIGYTSPDQELDYRTCQVMDCVEL 101
Query: 424 QSPNIAAGVHEN-RNDEEVGAGDQGLMFGLQQMRQKNACR*L*CLHTNSIRKLQSFRRNG 600
P++ G+ ++ AGDQG+ FG L R+L++ N
Sbjct: 102 H-PSLFNGISSGLEAPDDEPAGDQGMAFGYATDETPQLLPLTLHLAHRISRELKAAHTNR 160
Query: 601 RFWWARPDSK 630
W RPD+K
Sbjct: 161 ILPWLRPDTK 170
>UniRef50_Q4A5F4 Cluster: S-adenosylmethionine synthetase; n=4;
Bacteria|Rep: S-adenosylmethionine synthetase -
Mycoplasma synoviae (strain 53)
Length = 382
Score = 68.1 bits (159), Expect = 2e-10
Identities = 30/39 (76%), Positives = 35/39 (89%)
Frame = +2
Query: 143 LFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVALK 259
LFTSESVG GHPDK+CDQISDAILDA+L DP +KVA++
Sbjct: 4 LFTSESVGRGHPDKICDQISDAILDAYLTWDPHSKVAVE 42
Score = 56.4 bits (130), Expect = 6e-07
Identities = 31/88 (35%), Positives = 49/88 (55%)
Frame = +1
Query: 244 KSCIETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQ 423
K +ET+ V + GE+ SK VD ++ + +++IGY ++ F + +
Sbjct: 38 KVAVETMVSGNNVFIAGEVKSKVTVDVIEIAKNVLRNIGYYSNNTSF-------ITDIKS 90
Query: 424 QSPNIAAGVHENRNDEEVGAGDQGLMFG 507
QS NIA GV+ +D ++GAGDQG MFG
Sbjct: 91 QSENIAMGVNLQDSD-DLGAGDQGFMFG 117
>UniRef50_Q1GND0 Cluster: S-adenosylmethionine synthetase; n=29;
Alphaproteobacteria|Rep: S-adenosylmethionine synthetase
- Sphingopyxis alaskensis (Sphingomonas alaskensis)
Length = 406
Score = 61.7 bits (143), Expect = 2e-08
Identities = 27/38 (71%), Positives = 33/38 (86%)
Frame = +2
Query: 140 FLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVA 253
FLFTSESV EGHPDK+ DQISD+I+D L +DP+A+VA
Sbjct: 5 FLFTSESVSEGHPDKVADQISDSIVDLFLAKDPEARVA 42
Score = 56.8 bits (131), Expect = 5e-07
Identities = 41/100 (41%), Positives = 53/100 (53%), Gaps = 11/100 (11%)
Frame = +1
Query: 241 RKSCIETITKTGMVLLCGEITSK-----------ANVDYQKVVRETVKHIGYDDSSKGFD 387
R +C ET+T T +V+L GEI K A + + VR TV+ IGY+ + GF
Sbjct: 40 RVAC-ETLTTTQLVVLAGEIRCKGVFEDGEWAPGALDEIEATVRRTVREIGYEQA--GFH 96
Query: 388 YKTCSVMLALDQQSPNIAAGVHENRNDEEVGAGDQGLMFG 507
+ L QSP IA GV E +E GAGDQG+MFG
Sbjct: 97 WNRFRFENNLHGQSPQIAQGVDEGAGKDE-GAGDQGIMFG 135
>UniRef50_Q6KHY1 Cluster: S-adenosylmethionine synthetase; n=7;
Mycoplasma|Rep: S-adenosylmethionine synthetase -
Mycoplasma mobile
Length = 386
Score = 59.7 bits (138), Expect = 7e-08
Identities = 26/37 (70%), Positives = 33/37 (89%)
Frame = +2
Query: 143 LFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVA 253
+FTSESVG+GHPDK+CDQISD ILD+ L +D +A+VA
Sbjct: 5 IFTSESVGKGHPDKICDQISDRILDSILKKDCNARVA 41
Score = 41.1 bits (92), Expect = 0.025
Identities = 24/91 (26%), Positives = 54/91 (59%)
Frame = +1
Query: 235 SGRKSCIETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLA 414
+ R +C E + ++++ GEI + + +D K + +GYD++ D+ +++
Sbjct: 37 NARVAC-EVMASNKLIVIGGEIKTNSYIDVVKEAWNILLKLGYDEN----DF---TIISN 88
Query: 415 LDQQSPNIAAGVHENRNDEEVGAGDQGLMFG 507
+++QS +I+ GV ++++ + AGDQG++FG
Sbjct: 89 INKQSSDISFGV--DKSNGSIAAGDQGIVFG 117
>UniRef50_Q2LSR0 Cluster: S-adenosylmethionine synthetase; n=1;
Syntrophus aciditrophicus SB|Rep: S-adenosylmethionine
synthetase - Syntrophus aciditrophicus (strain SB)
Length = 392
Score = 59.3 bits (137), Expect = 9e-08
Identities = 28/86 (32%), Positives = 50/86 (58%), Gaps = 1/86 (1%)
Frame = +1
Query: 253 IETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSP 432
IE G+ ++ GE+ ++ VD ++ VR+TV +GY D G + + ++ + QSP
Sbjct: 47 IEVFLGKGLCIVGGEVATRIYVDIERCVRDTVLKLGYCDYELGLNGNSMGILNTIIPQSP 106
Query: 433 NIAAGVHENRND-EEVGAGDQGLMFG 507
+I G + +E+GAGDQG+++G
Sbjct: 107 DINIGTRADLGKYKEIGAGDQGIIYG 132
>UniRef50_Q5FGR4 Cluster: S-adenosylmethionine synthetase; n=13;
Rickettsiales|Rep: S-adenosylmethionine synthetase -
Ehrlichia ruminantium (strain Gardel)
Length = 401
Score = 58.4 bits (135), Expect = 2e-07
Identities = 32/90 (35%), Positives = 49/90 (54%), Gaps = 3/90 (3%)
Frame = +1
Query: 247 SCIETITKTGMVLLCGEITSKANVD---YQKVVRETVKHIGYDDSSKGFDYKTCSVMLAL 417
+ IET+ V + GEI NVD Q + R +K IGY+ GF ++ + + +
Sbjct: 47 TAIETLVTKNKVFIAGEICG-VNVDNSIIQSIARSVIKEIGYEQD--GFHWENVDIEILI 103
Query: 418 DQQSPNIAAGVHENRNDEEVGAGDQGLMFG 507
+QSP+I GV+ N GAGDQG+++G
Sbjct: 104 HEQSPDIIVGVNSGENQ---GAGDQGIVYG 130
Score = 51.2 bits (117), Expect = 2e-05
Identities = 22/42 (52%), Positives = 31/42 (73%)
Frame = +2
Query: 134 SVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVALK 259
S ++ TSESV GHPDK+ DQISDAILD +++ +P A++
Sbjct: 9 SSYIITSESVSSGHPDKIADQISDAILDYYISLNPFVHTAIE 50
>UniRef50_Q7NB16 Cluster: S-adenosylmethionine synthetase; n=2;
Mycoplasmataceae|Rep: S-adenosylmethionine synthetase -
Mycoplasma gallisepticum
Length = 395
Score = 57.6 bits (133), Expect = 3e-07
Identities = 24/37 (64%), Positives = 32/37 (86%)
Frame = +2
Query: 143 LFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVA 253
++T+ESVG HPDK+CDQI+DAILDA L QD +++VA
Sbjct: 22 VYTAESVGSAHPDKLCDQIADAILDACLKQDQNSRVA 58
Score = 51.2 bits (117), Expect = 2e-05
Identities = 32/99 (32%), Positives = 55/99 (55%)
Frame = +1
Query: 235 SGRKSCIETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLA 414
+ R +C E + ++++ GEI++KA+VDY + V GYD S D+ +++
Sbjct: 54 NSRVAC-EVMACNHLIIIAGEISTKASVDYVGTAWKVVNQFGYDRS----DF---TIIAN 105
Query: 415 LDQQSPNIAAGVHENRNDEEVGAGDQGLMFGLQQMRQKN 531
++QQS IA V ++ + ++GAGDQG+ G KN
Sbjct: 106 INQQSSEIAQSV--DQKNHKIGAGDQGITVGYACDETKN 142
>UniRef50_Q60BL6 Cluster: S-adenosylmethionine synthetase; n=6;
Bacteria|Rep: S-adenosylmethionine synthetase -
Methylococcus capsulatus
Length = 397
Score = 56.8 bits (131), Expect = 5e-07
Identities = 28/53 (52%), Positives = 35/53 (66%)
Frame = +2
Query: 140 FLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVALKP*LKPVWCFCVAK 298
FLFTSE+V EGHPD +CD ISDA++D L QDP A+V + L F A+
Sbjct: 5 FLFTSEAVTEGHPDCVCDIISDAVVDRFLQQDPYARVVTECALSKSVVFLAAR 57
>UniRef50_A6BGC6 Cluster: S-adenosylmethionine synthetase; n=1;
Dorea longicatena DSM 13814|Rep: S-adenosylmethionine
synthetase - Dorea longicatena DSM 13814
Length = 387
Score = 56.4 bits (130), Expect = 6e-07
Identities = 24/36 (66%), Positives = 30/36 (83%)
Frame = +2
Query: 146 FTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVA 253
+T+ESV EGHPDK+CDQI+DAILD L DP ++VA
Sbjct: 6 YTAESVTEGHPDKVCDQIADAILDECLRYDPSSRVA 41
Score = 38.7 bits (86), Expect = 0.13
Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 10/101 (9%)
Frame = +1
Query: 235 SGRKSCIETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLA 414
S R +C E + G V + GEITS V+R+ ++ GY + G + T
Sbjct: 37 SSRVAC-EVLATRGNVFVAGEITSGYEPPVFDVIRKVLEECGY--CTDGIEMDT-----F 88
Query: 415 LDQQSPNIAAGVHENR----------NDEEVGAGDQGLMFG 507
+ QQSP+IA V ++ D GAGDQG+M G
Sbjct: 89 VHQQSPDIAKAVSVSKEFRDNIGAKLRDRSRGAGDQGVMVG 129
>UniRef50_O09486 Cluster: S-adenosylmethionine synthetase; n=1;
Amoeba proteus|Rep: S-adenosylmethionine synthetase -
Amoeba proteus (Amoeba)
Length = 426
Score = 56.0 bits (129), Expect = 8e-07
Identities = 35/87 (40%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Frame = +1
Query: 253 IETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSP 432
+ET K +V L GE+T + RE V IGY D TCSV + + Q
Sbjct: 49 LETTIKGNVVGLFGEVTCQKTFPTISWFRELVTEIGYSREDLDLDPTTCSVHINVRGQEA 108
Query: 433 NIAAGVH--ENRNDEEVGAGDQGLMFG 507
I VH E E +GAGDQGLMFG
Sbjct: 109 EIRGVVHNQERAAKETLGAGDQGLMFG 135
Score = 49.6 bits (113), Expect = 7e-05
Identities = 21/44 (47%), Positives = 28/44 (63%)
Frame = +2
Query: 122 MEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVA 253
M+ + +LF SE+V GHPDK CDQ+SD +LD L + K A
Sbjct: 1 MQQNTRYLFASEAVSRGHPDKACDQVSDRVLDYCLQAEKKCKKA 44
>UniRef50_UPI00015BD1C2 Cluster: UPI00015BD1C2 related cluster; n=1;
unknown|Rep: UPI00015BD1C2 UniRef100 entry - unknown
Length = 372
Score = 54.8 bits (126), Expect = 2e-06
Identities = 37/127 (29%), Positives = 60/127 (47%), Gaps = 1/127 (0%)
Frame = +1
Query: 253 IETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSP 432
I + + +V + GE++S A VD Q V ++ +K +GY GFD V+ ++++QSP
Sbjct: 41 INVLLSSNIVFIAGEVSSSAYVDLQIVSKKAIKEVGYTKPEYGFDGDLIGVISSINEQSP 100
Query: 433 NIAAGVHENRNDEEVGAGDQGLMFGLQQMRQKNACR*L*CLHTNSIRKLQS-FRRNGRFW 609
IA + GAGD ++ G ++ + I K S FR+ G
Sbjct: 101 EIALCIASE------GAGDSAIVVGYATDETESFLP-APIYFAHKISKTTSDFRKKGIMP 153
Query: 610 WARPDSK 630
+ RPD K
Sbjct: 154 FLRPDGK 160
Score = 42.3 bits (95), Expect = 0.011
Identities = 18/35 (51%), Positives = 26/35 (74%)
Frame = +2
Query: 152 SESVGEGHPDKMCDQISDAILDAHLNQDPDAKVAL 256
+ES EGHPDK+ D ISD ILD + +DP ++V++
Sbjct: 7 AESPFEGHPDKLADIISDEILDEFMRKDPFSRVSI 41
>UniRef50_A6QA94 Cluster: S-adenosylmethionine synthetase; n=20;
Epsilonproteobacteria|Rep: S-adenosylmethionine
synthetase - Sulfurovum sp. (strain NBC37-1)
Length = 405
Score = 54.8 bits (126), Expect = 2e-06
Identities = 24/39 (61%), Positives = 31/39 (79%)
Frame = +2
Query: 137 VFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVA 253
++LFTSESV GHPDK D I+D I+D+ L +DP+AKVA
Sbjct: 1 MYLFTSESVSAGHPDKCADLIADTIVDSLLQRDPNAKVA 39
Score = 46.0 bits (104), Expect = 9e-04
Identities = 29/83 (34%), Positives = 49/83 (59%), Gaps = 7/83 (8%)
Frame = +1
Query: 280 VLLCGEI-TSKA--NVDYQKVVRETVKHIGYDDSS----KGFDYKTCSVMLALDQQSPNI 438
+++ GE+ TS A NV Y++ ++ ++ IGY + + F + + + +QSP+I
Sbjct: 49 IIIGGEVKTSTAVDNVFYEECAQKALEKIGYPEGGFKRGETFFPDEAEIEVYVSKQSPDI 108
Query: 439 AAGVHENRNDEEVGAGDQGLMFG 507
GV + N E+GAGDQG+MFG
Sbjct: 109 TMGVVKEGN--EIGAGDQGMMFG 129
>UniRef50_Q6SZ22 Cluster: S-adenosylmethionine synthetase; n=4;
Streptococcus|Rep: S-adenosylmethionine synthetase -
Streptococcus pyogenes
Length = 353
Score = 52.4 bits (120), Expect = 1e-05
Identities = 23/47 (48%), Positives = 32/47 (68%)
Frame = +2
Query: 131 GSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVALKP*LK 271
G + + +SE V GHPDK+CDQISDAIL L D ++VA++ +K
Sbjct: 6 GGIMIISSEQVSVGHPDKICDQISDAILTECLKYDKSSRVAVETLIK 52
Score = 42.7 bits (96), Expect = 0.008
Identities = 29/85 (34%), Positives = 45/85 (52%)
Frame = +1
Query: 253 IETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSP 432
+ET+ K V++ GEI+++ + + +VR+ V+ +G K V L QS
Sbjct: 47 VETLIKDNQVVVAGEISTRHYFNLENIVRQVVEPLG---------MKNVRVTNLLGLQSS 97
Query: 433 NIAAGVHENRNDEEVGAGDQGLMFG 507
+IA GV + GAGDQG+MFG
Sbjct: 98 DIAQGV------DNGGAGDQGMMFG 116
>UniRef50_Q2GDS4 Cluster: S-adenosylmethionine synthetase; n=1;
Neorickettsia sennetsu str. Miyayama|Rep:
S-adenosylmethionine synthetase - Neorickettsia sennetsu
(strain Miyayama)
Length = 382
Score = 52.0 bits (119), Expect = 1e-05
Identities = 22/43 (51%), Positives = 32/43 (74%)
Frame = +2
Query: 146 FTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVALKP*LKP 274
F+SE+V GHPDK+ DQISD +LD +L +DP ++VA + + P
Sbjct: 8 FSSEAVLPGHPDKIADQISDLVLDTYLQKDPSSRVAAETMVTP 50
Score = 51.2 bits (117), Expect = 2e-05
Identities = 30/86 (34%), Positives = 49/86 (56%), Gaps = 2/86 (2%)
Frame = +1
Query: 256 ETITKTGMVLLCGEITSK--ANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQS 429
ET+ V++ GEI N + ++ +R +K IGY+ D+++ ++ L +QS
Sbjct: 45 ETMVTPDRVIVAGEIYGPEVTNAELEEKIRLFLKGIGYEKHL--LDWESLEIVNLLHEQS 102
Query: 430 PNIAAGVHENRNDEEVGAGDQGLMFG 507
P I+AG+ R +GAGDQG+MFG
Sbjct: 103 PEISAGL---RRSASLGAGDQGVMFG 125
>UniRef50_P78003 Cluster: S-adenosylmethionine synthetase; n=4;
Mycoplasma|Rep: S-adenosylmethionine synthetase -
Mycoplasma pneumoniae
Length = 383
Score = 50.8 bits (116), Expect = 3e-05
Identities = 20/36 (55%), Positives = 28/36 (77%)
Frame = +2
Query: 146 FTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVA 253
+ +E+VG GHPDK+CDQI+D+ILD + Q P + VA
Sbjct: 13 YVAEAVGRGHPDKICDQIADSILDECIKQSPTSHVA 48
Score = 38.3 bits (85), Expect = 0.18
Identities = 25/94 (26%), Positives = 46/94 (48%)
Frame = +1
Query: 226 ESGSGRKSCIETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSV 405
+S + +C E ++++ GEI + VD + + + +GY ++ F + +C
Sbjct: 41 QSPTSHVAC-EVFASKNLIMVGGEILTTGYVDVVQTGWKVLNRLGYTEND--FSFLSC-- 95
Query: 406 MLALDQQSPNIAAGVHENRNDEEVGAGDQGLMFG 507
++ QS I V N +E+GAGDQG+ G
Sbjct: 96 ---INSQSSEINQAVQSN---DEIGAGDQGITVG 123
>UniRef50_Q7R6Z1 Cluster: Putative uncharacterized protein PY07799;
n=2; cellular organisms|Rep: Putative uncharacterized
protein PY07799 - Plasmodium yoelii yoelii
Length = 1022
Score = 47.2 bits (107), Expect = 4e-04
Identities = 32/99 (32%), Positives = 46/99 (46%)
Frame = -3
Query: 504 EHQALVSCPNFLVISVLMHPSSNVW*LLV*CEHHTACLVIKAFGRIIITNMFDRFAHNFL 325
EHQ LV+ F+V+ +H +V LL A L I+A +++ ++ AH FL
Sbjct: 901 EHQTLVARSLFVVVE-FVHTHGDVGRLLADGGQDGAALPIEADFGVVVADLVHDLAHQFL 959
Query: 324 IIHVSFGCDFATQKHHTGFSYGFNATFASGS*FRCASRI 208
+H G DFA + H G GF+ G C RI
Sbjct: 960 GVHPGGGGDFAGEHDHAGLHEGFHGHAGLG--ILCQDRI 996
>UniRef50_Q1VNA9 Cluster: S-adenosylmethionine synthetase; n=1;
Psychroflexus torquis ATCC 700755|Rep:
S-adenosylmethionine synthetase - Psychroflexus torquis
ATCC 700755
Length = 344
Score = 46.0 bits (104), Expect = 9e-04
Identities = 35/104 (33%), Positives = 54/104 (51%), Gaps = 7/104 (6%)
Frame = +1
Query: 217 RASESGSGRKSCIETI---TKTG-MVLLCGEITSKANV---DYQKVVRETVKHIGYDDSS 375
+A E+ + +ET+ TK G +V++ GEI+ AN+ D + +V E + S
Sbjct: 11 KALENNPSSRVAVETVLTGTKDGGLVMVGGEISEIANISTEDIKTIVHEALNKT-IKTSF 69
Query: 376 KGFDYKTCSVMLALDQQSPNIAAGVHENRNDEEVGAGDQGLMFG 507
+ F+ ++ L QS I A V E DE+ GAGDQG+M G
Sbjct: 70 EDFNLDRLNIYNELTPQSEEIRAAVEE---DEDQGAGDQGIMIG 110
>UniRef50_Q6A7D8 Cluster: S-adenosylmethionine synthetase; n=11;
Bacteria|Rep: S-adenosylmethionine synthetase -
Propionibacterium acnes
Length = 396
Score = 44.4 bits (100), Expect = 0.003
Identities = 21/37 (56%), Positives = 27/37 (72%)
Frame = +2
Query: 149 TSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVALK 259
T+ESV GHPDK+ DQI+D ILD L D A+VA++
Sbjct: 6 TAESVCAGHPDKLADQIADQILDDILYDDKAARVAVE 42
>UniRef50_Q95QX7 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 84
Score = 44.4 bits (100), Expect = 0.003
Identities = 18/19 (94%), Positives = 18/19 (94%)
Frame = +2
Query: 140 FLFTSESVGEGHPDKMCDQ 196
FLFTSESV EGHPDKMCDQ
Sbjct: 6 FLFTSESVSEGHPDKMCDQ 24
>UniRef50_A6PKG8 Cluster: Methionine adenosyltransferase precursor;
n=1; Victivallis vadensis ATCC BAA-548|Rep: Methionine
adenosyltransferase precursor - Victivallis vadensis
ATCC BAA-548
Length = 338
Score = 43.2 bits (97), Expect = 0.006
Identities = 21/43 (48%), Positives = 29/43 (67%)
Frame = +2
Query: 143 LFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVALKP*LK 271
L TSE V GHPDK+ D IS +LD HL++DP + A++ +K
Sbjct: 2 LKTSEWVSLGHPDKIADYISCYLLDRHLDRDPYTRFAVEVQIK 44
Score = 40.7 bits (91), Expect = 0.033
Identities = 35/96 (36%), Positives = 44/96 (45%), Gaps = 10/96 (10%)
Frame = +1
Query: 253 IETITKTGMVLLCGEITSKANV---DYQKVVRETVKHIGYDDSSK---GFDYKTCS---- 402
+E K V L GE+TSKAN D VR V IGY + G + C
Sbjct: 39 VEVQIKDNHVTLGGEVTSKANYSPEDIAAFVRAAVNQIGYTPEYQKRWGKENTICGDDLI 98
Query: 403 VMLALDQQSPNIAAGVHENRNDEEVGAGDQGLMFGL 510
V + QQSP+IA GV + G GDQG+ G+
Sbjct: 99 VTQHIGQQSPDIAQGVDAD------GYGDQGIFHGM 128
>UniRef50_Q027Y1 Cluster: Methionine adenosyltransferase; n=1;
Solibacter usitatus Ellin6076|Rep: Methionine
adenosyltransferase - Solibacter usitatus (strain
Ellin6076)
Length = 364
Score = 37.5 bits (83), Expect = 0.31
Identities = 15/39 (38%), Positives = 26/39 (66%)
Frame = +2
Query: 143 LFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVALK 259
L+ +E V GHPDK+CD I+DA+++ + + A A++
Sbjct: 2 LYAAEYVLPGHPDKLCDAIADALVEEAVRHEKRALCAIE 40
>UniRef50_A4HUR1 Cluster: Chromosome 10; n=3; Leishmania|Rep:
Chromosome 10 - Leishmania infantum
Length = 674
Score = 37.1 bits (82), Expect = 0.41
Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 3/52 (5%)
Frame = +2
Query: 524 RRMHA---VDCSACTQTQSENCRASGEMGDFGGQDQIQKTQVYLRICICLVV 670
+R HA +C +C CR + GG ++Q+ Q LR+C CL+V
Sbjct: 26 QRRHADVSFECGSCVSGAGVECRVAAGATAIGGAFRLQRKQTPLRVCACLLV 77
>UniRef50_UPI0000F1FBF8 Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 1206
Score = 36.3 bits (80), Expect = 0.71
Identities = 17/45 (37%), Positives = 26/45 (57%)
Frame = +2
Query: 524 RRMHAVDCSACTQTQSENCRASGEMGDFGGQDQIQKTQVYLRICI 658
RR+ C AC +T+ NC +M FGG +++K+ V LR C+
Sbjct: 496 RRVRCKRCEACLRTECGNCNYCRDMRKFGGPGRLKKSCV-LRQCL 539
>UniRef50_A4DEX8 Cluster: Putative uncharacterized protein; n=1;
Listeria monocytogenes FSL N1-017|Rep: Putative
uncharacterized protein - Listeria monocytogenes FSL
N1-017
Length = 277
Score = 35.5 bits (78), Expect = 1.2
Identities = 18/64 (28%), Positives = 34/64 (53%)
Frame = +2
Query: 155 ESVGEGHPDKMCDQISDAILDAHLNQDPDAKVALKP*LKPVWCFCVAKSHPKLTWIIKKL 334
E V HPDK+ D+IS AI+D ++ + K+A++ + C + ++ L++ +
Sbjct: 20 EKVNPSHPDKIADRISGAIVDLAYQEETNPKIAVEVLIGHGICHVIIETSAALSFEEVRK 79
Query: 335 CAKR 346
KR
Sbjct: 80 AIKR 83
>UniRef50_Q8FXU7 Cluster: Protease, putative; n=6; Brucellaceae|Rep:
Protease, putative - Brucella suis
Length = 261
Score = 35.1 bits (77), Expect = 1.6
Identities = 11/37 (29%), Positives = 24/37 (64%)
Frame = +2
Query: 116 YDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHL 226
YD + G++ + SE++G+GH + + D + A+ +A +
Sbjct: 50 YDSDSGAMLAYVSENIGKGHAEVLMDYVGQAMREAQI 86
>UniRef50_A1A5Z7 Cluster: Zgc:158441; n=7; Deuterostomia|Rep:
Zgc:158441 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 917
Score = 34.3 bits (75), Expect = 2.9
Identities = 16/45 (35%), Positives = 26/45 (57%)
Frame = +2
Query: 524 RRMHAVDCSACTQTQSENCRASGEMGDFGGQDQIQKTQVYLRICI 658
RR+ C AC +T+ +C +M FGG ++++T V LR C+
Sbjct: 122 RRVRCKRCEACLRTECGDCNFCRDMKKFGGPGKLKQTCV-LRQCL 165
>UniRef50_A4A0G4 Cluster: DNA-binding protein; n=1; Blastopirellula
marina DSM 3645|Rep: DNA-binding protein -
Blastopirellula marina DSM 3645
Length = 687
Score = 34.3 bits (75), Expect = 2.9
Identities = 14/35 (40%), Positives = 25/35 (71%)
Frame = +2
Query: 155 ESVGEGHPDKMCDQISDAILDAHLNQDPDAKVALK 259
++V GHP ++ + + DA+L+A + + PDAK+A K
Sbjct: 311 KAVRLGHPARVSESLHDALLEALVREHPDAKLAEK 345
>UniRef50_A6RT45 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 345
Score = 34.3 bits (75), Expect = 2.9
Identities = 14/34 (41%), Positives = 24/34 (70%)
Frame = +1
Query: 133 ISIFVHIGICWRGSSRQNVRPNKRRYSRRASESG 234
I+ +H+G+C G+SR++V+ +R SR+A SG
Sbjct: 282 IAWVIHVGMCCCGASRRDVKSGRRMGSRKAYSSG 315
>UniRef50_UPI00006A2011 Cluster: Tumor necrosis factor receptor
superfamily member 19L precursor (Receptor expressed in
lymphoid tissues).; n=1; Xenopus tropicalis|Rep: Tumor
necrosis factor receptor superfamily member 19L
precursor (Receptor expressed in lymphoid tissues). -
Xenopus tropicalis
Length = 313
Score = 33.9 bits (74), Expect = 3.8
Identities = 16/40 (40%), Positives = 19/40 (47%)
Frame = -2
Query: 487 LLPQLPRHFCSHAPQQQCLVIVGLVRASHCMSCNQSLWTN 368
LLPQ+P H C H + L S C C+Q WTN
Sbjct: 223 LLPQMP-HLCKHQHHLHTVQGPALPTGSCCSRCSQKKWTN 261
>UniRef50_Q15TP8 Cluster: Adenosine deaminase; n=2;
Gammaproteobacteria|Rep: Adenosine deaminase -
Pseudoalteromonas atlantica (strain T6c / BAA-1087)
Length = 537
Score = 33.9 bits (74), Expect = 3.8
Identities = 15/52 (28%), Positives = 26/52 (50%)
Frame = +1
Query: 316 VDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVHENRNDE 471
VD + + + +G +D+ KG+ + S + L Q+ PNI +H DE
Sbjct: 317 VDRHRDIYVGINMVGREDNDKGYPLRFLSTLRKLRQRIPNIPLAIHAGEVDE 368
>UniRef50_P37937 Cluster: Mating-type protein A-alpha Z3; n=1;
Schizophyllum commune|Rep: Mating-type protein A-alpha
Z3 - Schizophyllum commune (Bracket fungus)
Length = 891
Score = 33.5 bits (73), Expect = 5.0
Identities = 18/45 (40%), Positives = 26/45 (57%)
Frame = +1
Query: 169 GSSRQNVRPNKRRYSRRASESGSGRKSCIETITKTGMVLLCGEIT 303
G +R+ P KRR S RA E S ++ I +G+V++C EIT
Sbjct: 788 GITRRQTPPAKRRVSPRAQEPVEP-SSLVDDIISSGLVVVCKEIT 831
>UniRef50_Q4T9B3 Cluster: Chromosome undetermined SCAF7602, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF7602, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1251
Score = 33.1 bits (72), Expect = 6.6
Identities = 15/45 (33%), Positives = 26/45 (57%)
Frame = +2
Query: 524 RRMHAVDCSACTQTQSENCRASGEMGDFGGQDQIQKTQVYLRICI 658
RR+ C AC +++ +C +M FGG ++++T V LR C+
Sbjct: 509 RRVRCKRCEACVRSECGDCNFCRDMKKFGGPGKLKQTCV-LRQCL 552
>UniRef50_A3ES79 Cluster: Transposase; n=1; Leptospirillum sp. Group
II UBA|Rep: Transposase - Leptospirillum sp. Group II
UBA
Length = 377
Score = 33.1 bits (72), Expect = 6.6
Identities = 21/80 (26%), Positives = 36/80 (45%), Gaps = 4/80 (5%)
Frame = +1
Query: 247 SCIETITKTGMVLLCGEITSKANVDYQKVVRETVKHI-GYDDSSKGFDYK---TCSVMLA 414
S +E T G L+ + K V V + + G+ +S+ ++YK T S++ A
Sbjct: 186 SLVEQRTADGRSLITVSVDEKPGVQALATVSPDLPPVPGHHQTSRDYEYKRLGTVSILAA 245
Query: 415 LDQQSPNIAAGVHENRNDEE 474
LD Q + + VH+ E
Sbjct: 246 LDLQDGRVISQVHKKHRSRE 265
>UniRef50_A5AMB5 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 237
Score = 33.1 bits (72), Expect = 6.6
Identities = 23/73 (31%), Positives = 32/73 (43%)
Frame = +1
Query: 469 EEVGAGDQGLMFGLQQMRQKNACR*L*CLHTNSIRKLQSFRRNGRFWWARPDSKNTGLLA 648
+E+G GDQ MFG L T +L +NG + W RP+ K T ++
Sbjct: 145 KEIGVGDQSHMFGYATDDIPEFMPLNHVLATKLGARLSEVCKNGTYPWLRPNDK-TQVIV 203
Query: 649 NMYLPGGATVPHR 687
+ G A VP R
Sbjct: 204 KYHNDGDAMVPIR 216
>UniRef50_Q6CUT6 Cluster: Kluyveromyces lactis strain NRRL Y-1140
chromosome C of strain NRRL Y- 1140 of Kluyveromyces
lactis; n=1; Kluyveromyces lactis|Rep: Kluyveromyces
lactis strain NRRL Y-1140 chromosome C of strain NRRL Y-
1140 of Kluyveromyces lactis - Kluyveromyces lactis
(Yeast) (Candida sphaerica)
Length = 956
Score = 32.7 bits (71), Expect = 8.8
Identities = 14/48 (29%), Positives = 28/48 (58%)
Frame = +1
Query: 223 SESGSGRKSCIETITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYD 366
+ S SGRK +++T V L +T+K +V Y+K ++++ + +D
Sbjct: 204 ANSSSGRKVSSDSVTNIANVDLVDTVTTKEDVTYKKKRQDSISDLSFD 251
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 757,472,027
Number of Sequences: 1657284
Number of extensions: 16069496
Number of successful extensions: 42373
Number of sequences better than 10.0: 50
Number of HSP's better than 10.0 without gapping: 40654
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 42319
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 54545459628
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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