Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= NV060115.seq
(695 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Z11692-1|CAA77750.1| 858|Homo sapiens human elongation factor ... 113 4e-25
X51466-1|CAA35829.1| 858|Homo sapiens elongation factor 2 protein. 113 4e-25
BC126259-1|AAI26260.1| 858|Homo sapiens EEF2 protein protein. 113 4e-25
BC006547-1|AAH06547.1| 583|Homo sapiens EEF2 protein protein. 113 4e-25
AY942181-1|AAX34409.1| 858|Homo sapiens elongation factor 2 pro... 113 4e-25
D21163-1|BAA04699.2| 977|Homo sapiens KIAA0031 protein. 43 0.001
CR456774-1|CAG33055.1| 972|Homo sapiens U5-116KD protein. 43 0.001
BC024689-1|AAH24689.1| 517|Homo sapiens Similar to Elongation f... 43 0.001
BC002360-1|AAH02360.1| 972|Homo sapiens elongation factor Tu GT... 43 0.001
AJ505017-1|CAD43720.1| 850|Homo sapiens small nuclear ribonucle... 43 0.001
AL096771-1|CAM28080.1| 637|Homo sapiens collagen type XII alpha... 30 6.9
X90568-1|CAA62188.1|26926|Homo sapiens titin protein. 30 9.1
X64698-1|CAA45939.1| 1100|Homo sapiens titin protein. 30 9.1
AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein. 30 9.1
AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein. 30 9.1
>Z11692-1|CAA77750.1| 858|Homo sapiens human elongation factor 2
protein.
Length = 858
Score = 113 bits (273), Expect = 4e-25
Identities = 52/81 (64%), Positives = 61/81 (75%), Gaps = 1/81 (1%)
Frame = +2
Query: 8 RPILFMNKMDRXXXXXXXXXXXXYQTFQRIVENVNVIIATYXD-DGGPMGXVRVDPSKGS 184
+P+L MNKMDR YQTFQRIVENVNVII+TY + + GPMG + +DP G+
Sbjct: 152 KPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEGESGPMGNIMIDPVLGT 211
Query: 185 VGFGSGLHGWAFTLKQFSEMY 247
VGFGSGLHGWAFTLKQF+EMY
Sbjct: 212 VGFGSGLHGWAFTLKQFAEMY 232
Score = 75.4 bits (177), Expect = 2e-13
Identities = 48/143 (33%), Positives = 65/143 (45%), Gaps = 7/143 (4%)
Frame = +1
Query: 277 LMNRLWGENFFNPXTKKWSKQKDDDN----KRSFCMYVLDPIYXXFDAIMKFKKEEXDDL 444
+M +LWG+ +F+P K+SK R+FC +LDPI+ FDAIM FKKEE L
Sbjct: 256 MMKKLWGDRYFDPANGKFSKSATSPEGKKLPRTFCQLILDPIFKVFDAIMNFKKEETAKL 315
Query: 445 LXKIGVTIKHXDXXKDGKXXXXXXXXXXXXXVKXCFX*LPFIYHHL*WP---SKYRMEML 615
+ K+ + + D K+GK L I HL P KYR E+L
Sbjct: 316 IEKLDIKLDSEDKDKEGKPLLKAVMRRWLPAGDAL---LQMITIHLPSPVTAQKYRCELL 372
Query: 616 XRXXPIDG*SCPLGXXXCXXEGP 684
P D +G C +GP
Sbjct: 373 YEGPPDD--EAAMGIKSCDPKGP 393
>X51466-1|CAA35829.1| 858|Homo sapiens elongation factor 2 protein.
Length = 858
Score = 113 bits (273), Expect = 4e-25
Identities = 52/81 (64%), Positives = 61/81 (75%), Gaps = 1/81 (1%)
Frame = +2
Query: 8 RPILFMNKMDRXXXXXXXXXXXXYQTFQRIVENVNVIIATYXD-DGGPMGXVRVDPSKGS 184
+P+L MNKMDR YQTFQRIVENVNVII+TY + + GPMG + +DP G+
Sbjct: 152 KPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEGESGPMGNIMIDPVLGT 211
Query: 185 VGFGSGLHGWAFTLKQFSEMY 247
VGFGSGLHGWAFTLKQF+EMY
Sbjct: 212 VGFGSGLHGWAFTLKQFAEMY 232
Score = 75.4 bits (177), Expect = 2e-13
Identities = 48/143 (33%), Positives = 65/143 (45%), Gaps = 7/143 (4%)
Frame = +1
Query: 277 LMNRLWGENFFNPXTKKWSKQKDDDN----KRSFCMYVLDPIYXXFDAIMKFKKEEXDDL 444
+M +LWG+ +F+P K+SK R+FC +LDPI+ FDAIM FKKEE L
Sbjct: 256 MMKKLWGDRYFDPANGKFSKSATSPEGKKLPRTFCQLILDPIFKVFDAIMNFKKEETAKL 315
Query: 445 LXKIGVTIKHXDXXKDGKXXXXXXXXXXXXXVKXCFX*LPFIYHHL*WP---SKYRMEML 615
+ K+ + + D K+GK L I HL P KYR E+L
Sbjct: 316 IEKLDIKLDSEDKDKEGKPLLKAVMRRWLPAGDAL---LQMITIHLPSPVTAQKYRCELL 372
Query: 616 XRXXPIDG*SCPLGXXXCXXEGP 684
P D +G C +GP
Sbjct: 373 YEGPPDD--EAAMGIKSCDPKGP 393
>BC126259-1|AAI26260.1| 858|Homo sapiens EEF2 protein protein.
Length = 858
Score = 113 bits (273), Expect = 4e-25
Identities = 52/81 (64%), Positives = 61/81 (75%), Gaps = 1/81 (1%)
Frame = +2
Query: 8 RPILFMNKMDRXXXXXXXXXXXXYQTFQRIVENVNVIIATYXD-DGGPMGXVRVDPSKGS 184
+P+L MNKMDR YQTFQRIVENVNVII+TY + + GPMG + +DP G+
Sbjct: 152 KPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEGESGPMGNIMIDPVLGT 211
Query: 185 VGFGSGLHGWAFTLKQFSEMY 247
VGFGSGLHGWAFTLKQF+EMY
Sbjct: 212 VGFGSGLHGWAFTLKQFAEMY 232
Score = 75.4 bits (177), Expect = 2e-13
Identities = 48/143 (33%), Positives = 65/143 (45%), Gaps = 7/143 (4%)
Frame = +1
Query: 277 LMNRLWGENFFNPXTKKWSKQKDDDN----KRSFCMYVLDPIYXXFDAIMKFKKEEXDDL 444
+M +LWG+ +F+P K+SK R+FC +LDPI+ FDAIM FKKEE L
Sbjct: 256 MMKKLWGDRYFDPANGKFSKSATSPEGKKLPRTFCQLILDPIFKVFDAIMNFKKEETAKL 315
Query: 445 LXKIGVTIKHXDXXKDGKXXXXXXXXXXXXXVKXCFX*LPFIYHHL*WP---SKYRMEML 615
+ K+ + + D K+GK L I HL P KYR E+L
Sbjct: 316 IEKLDIKLDSEDKDKEGKPLLKAVMRRWLPAGDAL---LQMITIHLPSPVTAQKYRCELL 372
Query: 616 XRXXPIDG*SCPLGXXXCXXEGP 684
P D +G C +GP
Sbjct: 373 YEGPPDD--EAAMGIKSCDPKGP 393
>BC006547-1|AAH06547.1| 583|Homo sapiens EEF2 protein protein.
Length = 583
Score = 113 bits (273), Expect = 4e-25
Identities = 52/81 (64%), Positives = 61/81 (75%), Gaps = 1/81 (1%)
Frame = +2
Query: 8 RPILFMNKMDRXXXXXXXXXXXXYQTFQRIVENVNVIIATYXD-DGGPMGXVRVDPSKGS 184
+P+L MNKMDR YQTFQRIVENVNVII+TY + + GPMG + +DP G+
Sbjct: 152 KPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEGESGPMGNIMIDPVLGT 211
Query: 185 VGFGSGLHGWAFTLKQFSEMY 247
VGFGSGLHGWAFTLKQF+EMY
Sbjct: 212 VGFGSGLHGWAFTLKQFAEMY 232
Score = 75.4 bits (177), Expect = 2e-13
Identities = 48/143 (33%), Positives = 65/143 (45%), Gaps = 7/143 (4%)
Frame = +1
Query: 277 LMNRLWGENFFNPXTKKWSKQKDDDN----KRSFCMYVLDPIYXXFDAIMKFKKEEXDDL 444
+M +LWG+ +F+P K+SK R+FC +LDPI+ FDAIM FKKEE L
Sbjct: 256 MMKKLWGDRYFDPANGKFSKSATSPEGKKLPRTFCQLILDPIFKVFDAIMNFKKEETAKL 315
Query: 445 LXKIGVTIKHXDXXKDGKXXXXXXXXXXXXXVKXCFX*LPFIYHHL*WP---SKYRMEML 615
+ K+ + + D K+GK L I HL P KYR E+L
Sbjct: 316 IEKLDIKLDSEDKDKEGKPLLKAVMRRWLPAGDAL---LQMITIHLPSPVTAQKYRCELL 372
Query: 616 XRXXPIDG*SCPLGXXXCXXEGP 684
P D +G C +GP
Sbjct: 373 YEGPPDD--EAAMGIKSCDPKGP 393
>AY942181-1|AAX34409.1| 858|Homo sapiens elongation factor 2
protein.
Length = 858
Score = 113 bits (273), Expect = 4e-25
Identities = 52/81 (64%), Positives = 61/81 (75%), Gaps = 1/81 (1%)
Frame = +2
Query: 8 RPILFMNKMDRXXXXXXXXXXXXYQTFQRIVENVNVIIATYXD-DGGPMGXVRVDPSKGS 184
+P+L MNKMDR YQTFQRIVENVNVII+TY + + GPMG + +DP G+
Sbjct: 152 KPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEGESGPMGNIMIDPVLGT 211
Query: 185 VGFGSGLHGWAFTLKQFSEMY 247
VGFGSGLHGWAFTLKQF+EMY
Sbjct: 212 VGFGSGLHGWAFTLKQFAEMY 232
Score = 75.4 bits (177), Expect = 2e-13
Identities = 48/143 (33%), Positives = 65/143 (45%), Gaps = 7/143 (4%)
Frame = +1
Query: 277 LMNRLWGENFFNPXTKKWSKQKDDDN----KRSFCMYVLDPIYXXFDAIMKFKKEEXDDL 444
+M +LWG+ +F+P K+SK R+FC +LDPI+ FDAIM FKKEE L
Sbjct: 256 MMKKLWGDRYFDPANGKFSKSATSPEGKKLPRTFCQLILDPIFKVFDAIMNFKKEETAKL 315
Query: 445 LXKIGVTIKHXDXXKDGKXXXXXXXXXXXXXVKXCFX*LPFIYHHL*WP---SKYRMEML 615
+ K+ + + D K+GK L I HL P KYR E+L
Sbjct: 316 IEKLDIKLDSEDKDKEGKPLLKAVMRRWLPAGDAL---LQMITIHLPSPVTAQKYRCELL 372
Query: 616 XRXXPIDG*SCPLGXXXCXXEGP 684
P D +G C +GP
Sbjct: 373 YEGPPDD--EAAMGIKSCDPKGP 393
>D21163-1|BAA04699.2| 977|Homo sapiens KIAA0031 protein.
Length = 977
Score = 43.2 bits (97), Expect = 0.001
Identities = 17/45 (37%), Positives = 31/45 (68%), Gaps = 1/45 (2%)
Frame = +1
Query: 262 IDLVKLMNRLWGENFFNPXTKKWSKQ-KDDDNKRSFCMYVLDPIY 393
I+ + RLWG+ +FNP T+K++K+ ++RSF ++L+P+Y
Sbjct: 339 INYQEFAKRLWGDIYFNPKTRKFTKKAPTSSSQRSFVEFILEPLY 383
Score = 39.9 bits (89), Expect = 0.008
Identities = 24/77 (31%), Positives = 37/77 (48%)
Frame = +2
Query: 23 MNKMDRXXXXXXXXXXXXYQTFQRIVENVNVIIATYXDDGGPMGXVRVDPSKGSVGFGSG 202
+NK+DR Y + IV+ VN +I+ Y D + + P G+V F S
Sbjct: 262 INKIDRLILELKLPPTDAYYKLRHIVDEVNGLISMYSTDENLI----LSPLLGNVCFSSS 317
Query: 203 LHGWAFTLKQFSEMYAD 253
+ FTL F+++YAD
Sbjct: 318 QYSICFTLGSFAKIYAD 334
>CR456774-1|CAG33055.1| 972|Homo sapiens U5-116KD protein.
Length = 972
Score = 43.2 bits (97), Expect = 0.001
Identities = 17/45 (37%), Positives = 31/45 (68%), Gaps = 1/45 (2%)
Frame = +1
Query: 262 IDLVKLMNRLWGENFFNPXTKKWSKQ-KDDDNKRSFCMYVLDPIY 393
I+ + RLWG+ +FNP T+K++K+ ++RSF ++L+P+Y
Sbjct: 334 INYQEFAKRLWGDIYFNPKTRKFTKKAPTSSSQRSFVEFILEPLY 378
Score = 39.9 bits (89), Expect = 0.008
Identities = 24/77 (31%), Positives = 37/77 (48%)
Frame = +2
Query: 23 MNKMDRXXXXXXXXXXXXYQTFQRIVENVNVIIATYXDDGGPMGXVRVDPSKGSVGFGSG 202
+NK+DR Y + IV+ VN +I+ Y D + + P G+V F S
Sbjct: 257 INKIDRLILELKLPPTDAYYKLRHIVDEVNGLISMYSTDENLI----LSPLLGNVCFSSS 312
Query: 203 LHGWAFTLKQFSEMYAD 253
+ FTL F+++YAD
Sbjct: 313 QYSICFTLVSFAKIYAD 329
>BC024689-1|AAH24689.1| 517|Homo sapiens Similar to Elongation
factor 2b protein.
Length = 517
Score = 43.2 bits (97), Expect = 0.001
Identities = 18/24 (75%), Positives = 20/24 (83%)
Frame = +3
Query: 525 WLPXGEALLQXIAIHLPSPVVAQQ 596
WLP G+ALLQ I IHLPSPV AQ+
Sbjct: 2 WLPAGDALLQMITIHLPSPVTAQK 25
>BC002360-1|AAH02360.1| 972|Homo sapiens elongation factor Tu GTP
binding domain containing 2 protein.
Length = 972
Score = 43.2 bits (97), Expect = 0.001
Identities = 17/45 (37%), Positives = 31/45 (68%), Gaps = 1/45 (2%)
Frame = +1
Query: 262 IDLVKLMNRLWGENFFNPXTKKWSKQ-KDDDNKRSFCMYVLDPIY 393
I+ + RLWG+ +FNP T+K++K+ ++RSF ++L+P+Y
Sbjct: 334 INYQEFAKRLWGDIYFNPKTRKFTKKAPTSSSQRSFVEFILEPLY 378
Score = 39.9 bits (89), Expect = 0.008
Identities = 24/77 (31%), Positives = 37/77 (48%)
Frame = +2
Query: 23 MNKMDRXXXXXXXXXXXXYQTFQRIVENVNVIIATYXDDGGPMGXVRVDPSKGSVGFGSG 202
+NK+DR Y + IV+ VN +I+ Y D + + P G+V F S
Sbjct: 257 INKIDRLILELKLPPTDAYYKLRHIVDEVNGLISMYSTDENLI----LSPLLGNVCFSSS 312
Query: 203 LHGWAFTLKQFSEMYAD 253
+ FTL F+++YAD
Sbjct: 313 QYSICFTLVSFAKIYAD 329
>AJ505017-1|CAD43720.1| 850|Homo sapiens small nuclear
ribonucleoprotein component protein.
Length = 850
Score = 43.2 bits (97), Expect = 0.001
Identities = 17/45 (37%), Positives = 31/45 (68%), Gaps = 1/45 (2%)
Frame = +1
Query: 262 IDLVKLMNRLWGENFFNPXTKKWSKQ-KDDDNKRSFCMYVLDPIY 393
I+ + RLWG+ +FNP T+K++K+ ++RSF ++L+P+Y
Sbjct: 212 INYQEFAKRLWGDIYFNPKTRKFTKKAPTSSSQRSFVEFILEPLY 256
Score = 39.9 bits (89), Expect = 0.008
Identities = 24/77 (31%), Positives = 37/77 (48%)
Frame = +2
Query: 23 MNKMDRXXXXXXXXXXXXYQTFQRIVENVNVIIATYXDDGGPMGXVRVDPSKGSVGFGSG 202
+NK+DR Y + IV+ VN +I+ Y D + + P G+V F S
Sbjct: 135 INKIDRLILELKLPPTDAYYKLRHIVDEVNGLISMYSTDENLI----LSPLLGNVCFSSS 190
Query: 203 LHGWAFTLKQFSEMYAD 253
+ FTL F+++YAD
Sbjct: 191 QYSICFTLGSFAKIYAD 207
>AL096771-1|CAM28080.1| 637|Homo sapiens collagen type XII alpha 1
protein.
Length = 637
Score = 30.3 bits (65), Expect = 6.9
Identities = 13/39 (33%), Positives = 20/39 (51%)
Frame = -3
Query: 201 PDPKPTEPLLGSTRTSPMGPPSSXYVAIMTLTFSTIRWN 85
PD ++ L+GS RT P P + V T T++W+
Sbjct: 470 PDESESDDLIGSERTPPKSGPRNLQVYNATSNSLTVKWD 508
>X90568-1|CAA62188.1|26926|Homo sapiens titin protein.
Length = 26926
Score = 29.9 bits (64), Expect = 9.1
Identities = 17/53 (32%), Positives = 26/53 (49%), Gaps = 2/53 (3%)
Frame = -3
Query: 240 SENCLRVKA--HP*RPDPKPTEPLLGSTRTSPMGPPSSXYVAIMTLTFSTIRW 88
+E RV A H + +P +EP+ R P GPP V+ +T +T+ W
Sbjct: 14043 NEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSW 14095
>X64698-1|CAA45939.1| 1100|Homo sapiens titin protein.
Length = 1100
Score = 29.9 bits (64), Expect = 9.1
Identities = 17/53 (32%), Positives = 26/53 (49%), Gaps = 2/53 (3%)
Frame = -3
Query: 240 SENCLRVKA--HP*RPDPKPTEPLLGSTRTSPMGPPSSXYVAIMTLTFSTIRW 88
+E RV A H + +P +EP+ R P GPP V+ +T +T+ W
Sbjct: 447 NEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSW 499
>AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein.
Length = 30000
Score = 29.9 bits (64), Expect = 9.1
Identities = 17/53 (32%), Positives = 26/53 (49%), Gaps = 2/53 (3%)
Frame = -3
Query: 240 SENCLRVKA--HP*RPDPKPTEPLLGSTRTSPMGPPSSXYVAIMTLTFSTIRW 88
+E RV A H + +P +EP+ R P GPP V+ +T +T+ W
Sbjct: 21467 NEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSW 21519
>AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein.
Length = 26926
Score = 29.9 bits (64), Expect = 9.1
Identities = 17/53 (32%), Positives = 26/53 (49%), Gaps = 2/53 (3%)
Frame = -3
Query: 240 SENCLRVKA--HP*RPDPKPTEPLLGSTRTSPMGPPSSXYVAIMTLTFSTIRW 88
+E RV A H + +P +EP+ R P GPP V+ +T +T+ W
Sbjct: 14043 NEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSW 14095
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 92,501,136
Number of Sequences: 237096
Number of extensions: 1784173
Number of successful extensions: 3306
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 3067
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3283
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8007229802
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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