Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= NV060057.seq
(691 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC037798-1|AAH37798.1| 176|Homo sapiens TPPP3 protein protein. 69 2e-11
BC000691-1|AAH00691.1| 176|Homo sapiens brain specific protein ... 69 2e-11
AF132972-1|AAD27747.1| 176|Homo sapiens CGI-38 protein protein. 69 2e-11
BT020035-1|AAV38838.1| 219|Homo sapiens brain-specific protein ... 67 5e-11
BC131506-1|AAI31507.1| 219|Homo sapiens tubulin polymerization ... 67 5e-11
BC040496-1|AAH40496.1| 234|Homo sapiens TPPP protein protein. 67 5e-11
AY319261-1|AAQ96657.1| 219|Homo sapiens fibroblast growth facto... 67 5e-11
AB017016-1|BAA36164.1| 219|Homo sapiens p25 alpha protein. 67 5e-11
BC038970-1|AAH38970.1| 170|Homo sapiens tubulin polymerization-... 62 2e-09
AY173946-1|AAO49716.1| 170|Homo sapiens brain-specific protein ... 62 2e-09
AY072034-1|AAL62338.1| 170|Homo sapiens p25 beta protein. 62 2e-09
M24355-1|AAA52454.1| 416|Homo sapiens FLG protein. 30 8.9
AL356504-1|CAI19595.1| 4061|Homo sapiens filaggrin protein. 30 8.9
AB208881-1|BAD92118.1| 583|Homo sapiens PREDICTED: filaggrin va... 30 8.9
>BC037798-1|AAH37798.1| 176|Homo sapiens TPPP3 protein protein.
Length = 176
Score = 68.5 bits (160), Expect = 2e-11
Identities = 54/155 (34%), Positives = 79/155 (50%), Gaps = 12/155 (7%)
Frame = +3
Query: 261 GDPKSDGKAITLSQSDKWMKQAKVIXGKKITTTDTAIHFKKLKSVKLGIDDYQKF---LD 431
GDPK+ G+ + K K KV GK +T TD I F K+K + +Y++F L+
Sbjct: 21 GDPKASGQEMNGKNWAKLCKDCKVADGKSVTGTDVDIVFSKVKGKSARVINYEEFKKALE 80
Query: 432 DLA------KNKKVELDEIKKKLTTCGQPGITHTLQNHRQPQRP*ID*QTRANILVRTGS 593
+LA K+K+ D I + L +P + +D T + TGS
Sbjct: 81 ELATKRFKGKSKEEAFDAICQ-LVAGKEPANVGVTKAKTGGA---VDRLTDTSRY--TGS 134
Query: 594 ---AFDETGKGKGIAGRKDLVDGSGYVTGYQHXXT 689
FDE+GKGKGIAGR+D++D SGYV+ Y++ T
Sbjct: 135 HKERFDESGKGKGIAGRQDILDDSGYVSAYKNAGT 169
Score = 35.5 bits (78), Expect = 0.18
Identities = 17/24 (70%), Positives = 19/24 (79%)
Frame = +2
Query: 515 VTKSPAAAAAVDRLTDTSKYTGSH 586
VTK+ A VDRLTDTS+YTGSH
Sbjct: 113 VTKAKTGGA-VDRLTDTSRYTGSH 135
>BC000691-1|AAH00691.1| 176|Homo sapiens brain specific protein
protein.
Length = 176
Score = 68.5 bits (160), Expect = 2e-11
Identities = 54/155 (34%), Positives = 79/155 (50%), Gaps = 12/155 (7%)
Frame = +3
Query: 261 GDPKSDGKAITLSQSDKWMKQAKVIXGKKITTTDTAIHFKKLKSVKLGIDDYQKF---LD 431
GDPK+ G+ + K K KV GK +T TD I F K+K + +Y++F L+
Sbjct: 21 GDPKASGQEMNGKNWAKLCKDCKVADGKSVTGTDVDIVFSKVKGKSARVINYEEFKKALE 80
Query: 432 DLA------KNKKVELDEIKKKLTTCGQPGITHTLQNHRQPQRP*ID*QTRANILVRTGS 593
+LA K+K+ D I + L +P + +D T + TGS
Sbjct: 81 ELATKRFKGKSKEEAFDAICQ-LVAGKEPANVGVTKAKTGGA---VDRLTDTSRY--TGS 134
Query: 594 ---AFDETGKGKGIAGRKDLVDGSGYVTGYQHXXT 689
FDE+GKGKGIAGR+D++D SGYV+ Y++ T
Sbjct: 135 HKERFDESGKGKGIAGRQDILDDSGYVSAYKNAGT 169
Score = 35.5 bits (78), Expect = 0.18
Identities = 17/24 (70%), Positives = 19/24 (79%)
Frame = +2
Query: 515 VTKSPAAAAAVDRLTDTSKYTGSH 586
VTK+ A VDRLTDTS+YTGSH
Sbjct: 113 VTKAKTGGA-VDRLTDTSRYTGSH 135
>AF132972-1|AAD27747.1| 176|Homo sapiens CGI-38 protein protein.
Length = 176
Score = 68.5 bits (160), Expect = 2e-11
Identities = 54/155 (34%), Positives = 79/155 (50%), Gaps = 12/155 (7%)
Frame = +3
Query: 261 GDPKSDGKAITLSQSDKWMKQAKVIXGKKITTTDTAIHFKKLKSVKLGIDDYQKF---LD 431
GDPK+ G+ + K K KV GK +T TD I F K+K + +Y++F L+
Sbjct: 21 GDPKASGQEMNGKNWAKLCKDCKVADGKSVTGTDVDIVFSKVKGKSARVINYEEFKKALE 80
Query: 432 DLA------KNKKVELDEIKKKLTTCGQPGITHTLQNHRQPQRP*ID*QTRANILVRTGS 593
+LA K+K+ D I + L +P + +D T + TGS
Sbjct: 81 ELATKRFQGKSKEEAFDAICQ-LVAGKEPANVGVTKAKTGGA---VDRLTDTSRY--TGS 134
Query: 594 ---AFDETGKGKGIAGRKDLVDGSGYVTGYQHXXT 689
FDE+GKGKGIAGR+D++D SGYV+ Y++ T
Sbjct: 135 HKERFDESGKGKGIAGRQDILDDSGYVSAYKNAGT 169
Score = 35.5 bits (78), Expect = 0.18
Identities = 17/24 (70%), Positives = 19/24 (79%)
Frame = +2
Query: 515 VTKSPAAAAAVDRLTDTSKYTGSH 586
VTK+ A VDRLTDTS+YTGSH
Sbjct: 113 VTKAKTGGA-VDRLTDTSRYTGSH 135
>BT020035-1|AAV38838.1| 219|Homo sapiens brain-specific protein p25
alpha protein.
Length = 219
Score = 67.3 bits (157), Expect = 5e-11
Identities = 51/154 (33%), Positives = 78/154 (50%), Gaps = 11/154 (7%)
Frame = +3
Query: 261 GDPKSDGKAITLSQSDKWMKQAKVIXGKKITTTDTAIHFKKLKSVK---LGIDDYQKFLD 431
GD ++ G+ + K K +VI G+ +T TD I F K+K + + +Q+ L+
Sbjct: 62 GDARATGREMHGKNWSKLCKDCQVIDGRNVTVTDVDIVFSKIKGKSCRTITFEQFQEALE 121
Query: 432 DLAKNK---KVELDEIKK--KLTTCGQPGITHTLQNHRQPQRP*ID*QTRANILVRTGS- 593
+LAK + K + +++ +L P I+ + P + T+ TGS
Sbjct: 122 ELAKKRFKDKSSEEAVREVHRLIEGKAPIISGVTKAISSPTVSRLTDTTKF-----TGSH 176
Query: 594 --AFDETGKGKGIAGRKDLVDGSGYVTGYQHXXT 689
FD +GKGKG AGR DLVD SGYV+GY+H T
Sbjct: 177 KERFDPSGKGKGKAGRVDLVDESGYVSGYKHAGT 210
Score = 31.1 bits (67), Expect = 3.9
Identities = 15/26 (57%), Positives = 20/26 (76%)
Frame = +2
Query: 509 SHVTKSPAAAAAVDRLTDTSKYTGSH 586
S VTK+ ++ V RLTDT+K+TGSH
Sbjct: 152 SGVTKA-ISSPTVSRLTDTTKFTGSH 176
>BC131506-1|AAI31507.1| 219|Homo sapiens tubulin polymerization
promoting protein protein.
Length = 219
Score = 67.3 bits (157), Expect = 5e-11
Identities = 51/154 (33%), Positives = 78/154 (50%), Gaps = 11/154 (7%)
Frame = +3
Query: 261 GDPKSDGKAITLSQSDKWMKQAKVIXGKKITTTDTAIHFKKLKSVK---LGIDDYQKFLD 431
GD ++ G+ + K K +VI G+ +T TD I F K+K + + +Q+ L+
Sbjct: 62 GDARATGREMHGKNWSKLCKDCQVIDGRNVTVTDVDIVFSKIKGKSCRTITFEQFQEALE 121
Query: 432 DLAKNK---KVELDEIKK--KLTTCGQPGITHTLQNHRQPQRP*ID*QTRANILVRTGS- 593
+LAK + K + +++ +L P I+ + P + T+ TGS
Sbjct: 122 ELAKKRFKDKSSEEAVREVHRLIEGKAPIISGVTKAISSPTVSRLTDTTKF-----TGSH 176
Query: 594 --AFDETGKGKGIAGRKDLVDGSGYVTGYQHXXT 689
FD +GKGKG AGR DLVD SGYV+GY+H T
Sbjct: 177 KERFDPSGKGKGKAGRVDLVDESGYVSGYKHAGT 210
Score = 31.1 bits (67), Expect = 3.9
Identities = 15/26 (57%), Positives = 20/26 (76%)
Frame = +2
Query: 509 SHVTKSPAAAAAVDRLTDTSKYTGSH 586
S VTK+ ++ V RLTDT+K+TGSH
Sbjct: 152 SGVTKA-ISSPTVSRLTDTTKFTGSH 176
>BC040496-1|AAH40496.1| 234|Homo sapiens TPPP protein protein.
Length = 234
Score = 67.3 bits (157), Expect = 5e-11
Identities = 51/154 (33%), Positives = 78/154 (50%), Gaps = 11/154 (7%)
Frame = +3
Query: 261 GDPKSDGKAITLSQSDKWMKQAKVIXGKKITTTDTAIHFKKLKSVK---LGIDDYQKFLD 431
GD ++ G+ + K K +VI G+ +T TD I F K+K + + +Q+ L+
Sbjct: 77 GDARATGREMHGKNWSKLCKDCQVIDGRNVTVTDVDIVFSKIKGKSCRTITFEQFQEALE 136
Query: 432 DLAKNK---KVELDEIKK--KLTTCGQPGITHTLQNHRQPQRP*ID*QTRANILVRTGS- 593
+LAK + K + +++ +L P I+ + P + T+ TGS
Sbjct: 137 ELAKKRFKDKSSEEAVREVHRLIEGKAPIISGVTKAISSPTVSRLTDTTKF-----TGSH 191
Query: 594 --AFDETGKGKGIAGRKDLVDGSGYVTGYQHXXT 689
FD +GKGKG AGR DLVD SGYV+GY+H T
Sbjct: 192 KERFDPSGKGKGKAGRVDLVDESGYVSGYKHAGT 225
Score = 31.1 bits (67), Expect = 3.9
Identities = 15/26 (57%), Positives = 20/26 (76%)
Frame = +2
Query: 509 SHVTKSPAAAAAVDRLTDTSKYTGSH 586
S VTK+ ++ V RLTDT+K+TGSH
Sbjct: 167 SGVTKA-ISSPTVSRLTDTTKFTGSH 191
>AY319261-1|AAQ96657.1| 219|Homo sapiens fibroblast growth factor-2
repression protein-1 protein.
Length = 219
Score = 67.3 bits (157), Expect = 5e-11
Identities = 51/154 (33%), Positives = 78/154 (50%), Gaps = 11/154 (7%)
Frame = +3
Query: 261 GDPKSDGKAITLSQSDKWMKQAKVIXGKKITTTDTAIHFKKLKSVK---LGIDDYQKFLD 431
GD ++ G+ + K K +VI G+ +T TD I F K+K + + +Q+ L+
Sbjct: 62 GDARATGREMHGKNWSKLCKDCQVIDGRNVTVTDVDIVFSKIKGKSCRTITFEQFQEALE 121
Query: 432 DLAKNK---KVELDEIKK--KLTTCGQPGITHTLQNHRQPQRP*ID*QTRANILVRTGS- 593
+LAK + K + +++ +L P I+ + P + T+ TGS
Sbjct: 122 ELAKKRFKDKSSEEAVREVHRLIEGKAPIISGVTKAISSPTVSRLTDTTKF-----TGSH 176
Query: 594 --AFDETGKGKGIAGRKDLVDGSGYVTGYQHXXT 689
FD +GKGKG AGR DLVD SGYV+GY+H T
Sbjct: 177 KERFDPSGKGKGKAGRVDLVDESGYVSGYKHAGT 210
Score = 31.1 bits (67), Expect = 3.9
Identities = 15/26 (57%), Positives = 20/26 (76%)
Frame = +2
Query: 509 SHVTKSPAAAAAVDRLTDTSKYTGSH 586
S VTK+ ++ V RLTDT+K+TGSH
Sbjct: 152 SGVTKA-ISSPTVSRLTDTTKFTGSH 176
>AB017016-1|BAA36164.1| 219|Homo sapiens p25 alpha protein.
Length = 219
Score = 67.3 bits (157), Expect = 5e-11
Identities = 51/154 (33%), Positives = 78/154 (50%), Gaps = 11/154 (7%)
Frame = +3
Query: 261 GDPKSDGKAITLSQSDKWMKQAKVIXGKKITTTDTAIHFKKLKSVK---LGIDDYQKFLD 431
GD ++ G+ + K K +VI G+ +T TD I F K+K + + +Q+ L+
Sbjct: 62 GDARATGREMHGKNWSKLCKDCQVIDGRNVTVTDVDIVFSKIKGKSCRTITFEQFQEALE 121
Query: 432 DLAKNK---KVELDEIKK--KLTTCGQPGITHTLQNHRQPQRP*ID*QTRANILVRTGS- 593
+LAK + K + +++ +L P I+ + P + T+ TGS
Sbjct: 122 ELAKKRFKDKSSEEAVREVHRLIEGKAPIISGVTKAISSPTVSRLTDTTKF-----TGSH 176
Query: 594 --AFDETGKGKGIAGRKDLVDGSGYVTGYQHXXT 689
FD +GKGKG AGR DLVD SGYV+GY+H T
Sbjct: 177 KERFDPSGKGKGKAGRVDLVDESGYVSGYKHAGT 210
Score = 31.1 bits (67), Expect = 3.9
Identities = 15/26 (57%), Positives = 20/26 (76%)
Frame = +2
Query: 509 SHVTKSPAAAAAVDRLTDTSKYTGSH 586
S VTK+ ++ V RLTDT+K+TGSH
Sbjct: 152 SGVTKA-ISSPTVSRLTDTTKFTGSH 176
>BC038970-1|AAH38970.1| 170|Homo sapiens tubulin
polymerization-promoting protein family member 2
protein.
Length = 170
Score = 61.7 bits (143), Expect = 2e-09
Identities = 44/150 (29%), Positives = 71/150 (47%), Gaps = 6/150 (4%)
Frame = +3
Query: 258 FGDPKSDGKAITLSQSDKWMKQAKVIXGKKITTTDTAIHFKKLKSVKLGIDDYQKFLD-- 431
FG+ S G + K K ++ GK +T+TD I F K+K+ +Q+F +
Sbjct: 15 FGESSSSGTEMNNKNFSKLCKDCGIMDGKTVTSTDVDIVFSKVKAKNARTITFQQFKEAV 74
Query: 432 -DLAKN--KKVELDEIKKKLTTCGQPGITHTLQNHRQPQRP*ID*QTRANILVRTGSA-F 599
+L + K DE+ + + + T + +D T + T F
Sbjct: 75 KELGQKRFKGKSPDEVLENIYGLMEGKDPATTGATKATTVGAVDRLTDTSKYTGTHKELF 134
Query: 600 DETGKGKGIAGRKDLVDGSGYVTGYQHXXT 689
DE+GKGKGIAGR+++ D +GYV+GY+ T
Sbjct: 135 DESGKGKGIAGREEMTDNTGYVSGYKGSGT 164
>AY173946-1|AAO49716.1| 170|Homo sapiens brain-specific protein
p25-like protein protein.
Length = 170
Score = 61.7 bits (143), Expect = 2e-09
Identities = 44/150 (29%), Positives = 71/150 (47%), Gaps = 6/150 (4%)
Frame = +3
Query: 258 FGDPKSDGKAITLSQSDKWMKQAKVIXGKKITTTDTAIHFKKLKSVKLGIDDYQKFLD-- 431
FG+ S G + K K ++ GK +T+TD I F K+K+ +Q+F +
Sbjct: 15 FGESSSSGTEMNNKNFSKLCKDCGIMDGKTVTSTDVDIVFSKVKAKNARTITFQQFKEAV 74
Query: 432 -DLAKN--KKVELDEIKKKLTTCGQPGITHTLQNHRQPQRP*ID*QTRANILVRTGSA-F 599
+L + K DE+ + + + T + +D T + T F
Sbjct: 75 KELGQKRFKGKSPDEVLENIYGLMEGKDPATTGATKATTVGAVDRLTDTSKYTGTHKELF 134
Query: 600 DETGKGKGIAGRKDLVDGSGYVTGYQHXXT 689
DE+GKGKGIAGR+++ D +GYV+GY+ T
Sbjct: 135 DESGKGKGIAGREEMTDNTGYVSGYKGSGT 164
>AY072034-1|AAL62338.1| 170|Homo sapiens p25 beta protein.
Length = 170
Score = 61.7 bits (143), Expect = 2e-09
Identities = 44/150 (29%), Positives = 71/150 (47%), Gaps = 6/150 (4%)
Frame = +3
Query: 258 FGDPKSDGKAITLSQSDKWMKQAKVIXGKKITTTDTAIHFKKLKSVKLGIDDYQKFLD-- 431
FG+ S G + K K ++ GK +T+TD I F K+K+ +Q+F +
Sbjct: 15 FGESSSSGTEMNNKNFSKLCKDCGIMDGKTVTSTDVDIVFSKVKAKNARTITFQQFKEAV 74
Query: 432 -DLAKN--KKVELDEIKKKLTTCGQPGITHTLQNHRQPQRP*ID*QTRANILVRTGSA-F 599
+L + K DE+ + + + T + +D T + T F
Sbjct: 75 KELGQKRFKGKSPDEVLENIYGLMEGKDPATTGATKATTVGAVDRLTDTSKYTGTHKELF 134
Query: 600 DETGKGKGIAGRKDLVDGSGYVTGYQHXXT 689
DE+GKGKGIAGR+++ D +GYV+GY+ T
Sbjct: 135 DESGKGKGIAGREEMTDNTGYVSGYKGSGT 164
>M24355-1|AAA52454.1| 416|Homo sapiens FLG protein.
Length = 416
Score = 29.9 bits (64), Expect = 8.9
Identities = 12/42 (28%), Positives = 23/42 (54%)
Frame = +2
Query: 281 KSHHALAKRQMDETSQSYXWKENNNNGHGYSLQKTQIGKTRH 406
++HH A+ Q+ + S+ + + GHG+S ++ TRH
Sbjct: 201 RNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRH 242
>AL356504-1|CAI19595.1| 4061|Homo sapiens filaggrin protein.
Length = 4061
Score = 29.9 bits (64), Expect = 8.9
Identities = 12/42 (28%), Positives = 23/42 (54%)
Frame = +2
Query: 281 KSHHALAKRQMDETSQSYXWKENNNNGHGYSLQKTQIGKTRH 406
++HH A+ Q+ + S+ + + GHG+S ++ TRH
Sbjct: 2589 RNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRH 2630
Score = 29.9 bits (64), Expect = 8.9
Identities = 12/42 (28%), Positives = 23/42 (54%)
Frame = +2
Query: 281 KSHHALAKRQMDETSQSYXWKENNNNGHGYSLQKTQIGKTRH 406
++HH A+ Q+ + S+ + + GHG+S ++ TRH
Sbjct: 2913 RNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRH 2954
>AB208881-1|BAD92118.1| 583|Homo sapiens PREDICTED: filaggrin
variant protein.
Length = 583
Score = 29.9 bits (64), Expect = 8.9
Identities = 12/42 (28%), Positives = 23/42 (54%)
Frame = +2
Query: 281 KSHHALAKRQMDETSQSYXWKENNNNGHGYSLQKTQIGKTRH 406
++HH A+ Q+ + S+ + + GHG+S ++ TRH
Sbjct: 105 RNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRH 146
Score = 29.9 bits (64), Expect = 8.9
Identities = 12/42 (28%), Positives = 23/42 (54%)
Frame = +2
Query: 281 KSHHALAKRQMDETSQSYXWKENNNNGHGYSLQKTQIGKTRH 406
++HH A+ Q+ + S+ + + GHG+S ++ TRH
Sbjct: 429 RNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRH 470
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 92,328,439
Number of Sequences: 237096
Number of extensions: 1829339
Number of successful extensions: 4879
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 4639
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4873
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7895240574
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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