Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= NV021936
(746 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC098386-1|AAH98386.1| 336|Homo sapiens vacuolar protein sortin... 140 5e-33
BC014128-1|AAH14128.1| 336|Homo sapiens vacuolar protein sortin... 139 1e-32
BC009747-1|AAH09747.1| 336|Homo sapiens vacuolar protein sortin... 139 1e-32
BC022505-1|AAH22505.1| 327|Homo sapiens vacuolar protein sortin... 128 2e-29
AL596223-4|CAH71501.1| 327|Homo sapiens vacuolar protein sortin... 128 2e-29
AL442635-2|CAH71779.1| 327|Homo sapiens vacuolar protein sortin... 128 2e-29
AF175266-1|AAF89954.1| 327|Homo sapiens vacuolar sorting protei... 128 2e-29
AK022992-1|BAB14351.1| 327|Homo sapiens protein ( Homo sapiens ... 127 4e-29
D87343-1|BAA23225.1| 297|Homo sapiens DCRA protein. 31 3.3
BC110655-1|AAI10656.1| 297|Homo sapiens Down syndrome critical ... 31 3.3
>BC098386-1|AAH98386.1| 336|Homo sapiens vacuolar protein sorting
26 homolog B (S. pombe) protein.
Length = 336
Score = 140 bits (339), Expect = 5e-33
Identities = 60/85 (70%), Positives = 73/85 (85%)
Frame = +3
Query: 255 SGKVNVTLRKPGSKLEHQGIKVELIGQIELFYDRGNHHEFISLVKELARPGDLLQHTSYP 434
SGKV++ LR P +LEHQGIK+E IGQIEL+YDRGNHHEF+SLVK+LARPG++ Q ++
Sbjct: 47 SGKVSLALRNPNKRLEHQGIKIEFIGQIELYYDRGNHHEFVSLVKDLARPGEITQSQAFD 106
Query: 435 FEFANVEKPYEVYTGSNVRLRYFLR 509
FEF +VEKPYE YTG NV+LRYFLR
Sbjct: 107 FEFTHVEKPYESYTGQNVKLRYFLR 131
Score = 123 bits (297), Expect = 6e-28
Identities = 58/73 (79%), Positives = 64/73 (87%)
Frame = +2
Query: 500 FPAATIVRCLTDITKEVDIAVHTLCSYPDVLNSIKMEVGIEDCLHIEFEYNKSKYHLKDV 679
F ATI R L D+ KE+DI VHTL +YP++ +SIKMEVGIEDCLHIEFEYNKSKYHLKDV
Sbjct: 129 FLRATISRRLNDVVKEMDIVVHTLSTYPELNSSIKMEVGIEDCLHIEFEYNKSKYHLKDV 188
Query: 680 IVGKIYFLLVRIK 718
IVGKIYFLLVRIK
Sbjct: 189 IVGKIYFLLVRIK 201
Score = 76.2 bits (179), Expect = 1e-13
Identities = 33/49 (67%), Positives = 41/49 (83%)
Frame = +1
Query: 118 MSFFGFGQTADIEIVFDDADKRKVAEVKTDDGKKEKLLLYYDGETVPGK 264
MSFFGFGQ+ ++EI+ +DA+ RK AE KT+DGKKEK L+YDGETV GK
Sbjct: 1 MSFFGFGQSVEVEILLNDAESRKRAEHKTEDGKKEKYFLFYDGETVSGK 49
>BC014128-1|AAH14128.1| 336|Homo sapiens vacuolar protein sorting
26 homolog B (S. pombe) protein.
Length = 336
Score = 139 bits (336), Expect = 1e-32
Identities = 59/85 (69%), Positives = 73/85 (85%)
Frame = +3
Query: 255 SGKVNVTLRKPGSKLEHQGIKVELIGQIELFYDRGNHHEFISLVKELARPGDLLQHTSYP 434
SGKV++ L+ P +LEHQGIK+E IGQIEL+YDRGNHHEF+SLVK+LARPG++ Q ++
Sbjct: 47 SGKVSLALKNPNKRLEHQGIKIEFIGQIELYYDRGNHHEFVSLVKDLARPGEITQSQAFD 106
Query: 435 FEFANVEKPYEVYTGSNVRLRYFLR 509
FEF +VEKPYE YTG NV+LRYFLR
Sbjct: 107 FEFTHVEKPYESYTGQNVKLRYFLR 131
Score = 123 bits (297), Expect = 6e-28
Identities = 58/73 (79%), Positives = 64/73 (87%)
Frame = +2
Query: 500 FPAATIVRCLTDITKEVDIAVHTLCSYPDVLNSIKMEVGIEDCLHIEFEYNKSKYHLKDV 679
F ATI R L D+ KE+DI VHTL +YP++ +SIKMEVGIEDCLHIEFEYNKSKYHLKDV
Sbjct: 129 FLRATISRRLNDVVKEMDIVVHTLSTYPELNSSIKMEVGIEDCLHIEFEYNKSKYHLKDV 188
Query: 680 IVGKIYFLLVRIK 718
IVGKIYFLLVRIK
Sbjct: 189 IVGKIYFLLVRIK 201
Score = 76.2 bits (179), Expect = 1e-13
Identities = 33/49 (67%), Positives = 41/49 (83%)
Frame = +1
Query: 118 MSFFGFGQTADIEIVFDDADKRKVAEVKTDDGKKEKLLLYYDGETVPGK 264
MSFFGFGQ+ ++EI+ +DA+ RK AE KT+DGKKEK L+YDGETV GK
Sbjct: 1 MSFFGFGQSVEVEILLNDAESRKRAEHKTEDGKKEKYFLFYDGETVSGK 49
>BC009747-1|AAH09747.1| 336|Homo sapiens vacuolar protein sorting
26 homolog B (S. pombe) protein.
Length = 336
Score = 139 bits (336), Expect = 1e-32
Identities = 59/85 (69%), Positives = 73/85 (85%)
Frame = +3
Query: 255 SGKVNVTLRKPGSKLEHQGIKVELIGQIELFYDRGNHHEFISLVKELARPGDLLQHTSYP 434
SGKV++ L+ P +LEHQGIK+E IGQIEL+YDRGNHHEF+SLVK+LARPG++ Q ++
Sbjct: 47 SGKVSLALKNPNKRLEHQGIKIEFIGQIELYYDRGNHHEFVSLVKDLARPGEITQSQAFD 106
Query: 435 FEFANVEKPYEVYTGSNVRLRYFLR 509
FEF +VEKPYE YTG NV+LRYFLR
Sbjct: 107 FEFTHVEKPYESYTGQNVKLRYFLR 131
Score = 123 bits (297), Expect = 6e-28
Identities = 58/73 (79%), Positives = 64/73 (87%)
Frame = +2
Query: 500 FPAATIVRCLTDITKEVDIAVHTLCSYPDVLNSIKMEVGIEDCLHIEFEYNKSKYHLKDV 679
F ATI R L D+ KE+DI VHTL +YP++ +SIKMEVGIEDCLHIEFEYNKSKYHLKDV
Sbjct: 129 FLRATISRRLNDVVKEMDIVVHTLSTYPELNSSIKMEVGIEDCLHIEFEYNKSKYHLKDV 188
Query: 680 IVGKIYFLLVRIK 718
IVGKIYFLLVRIK
Sbjct: 189 IVGKIYFLLVRIK 201
Score = 76.2 bits (179), Expect = 1e-13
Identities = 33/49 (67%), Positives = 41/49 (83%)
Frame = +1
Query: 118 MSFFGFGQTADIEIVFDDADKRKVAEVKTDDGKKEKLLLYYDGETVPGK 264
MSFFGFGQ+ ++EI+ +DA+ RK AE KT+DGKKEK L+YDGETV GK
Sbjct: 1 MSFFGFGQSVEVEILLNDAESRKRAEHKTEDGKKEKYFLFYDGETVSGK 49
>BC022505-1|AAH22505.1| 327|Homo sapiens vacuolar protein sorting
26 homolog A (S. pombe) protein.
Length = 327
Score = 128 bits (310), Expect = 2e-29
Identities = 56/85 (65%), Positives = 69/85 (81%)
Frame = +3
Query: 255 SGKVNVTLRKPGSKLEHQGIKVELIGQIELFYDRGNHHEFISLVKELARPGDLLQHTSYP 434
SGKVN+ ++PG +LEHQGI++E +GQIELF D+ N HEF++LVKELA PG+L Q SY
Sbjct: 49 SGKVNLAFKQPGKRLEHQGIRIEFVGQIELFNDKSNTHEFVNLVKELALPGELTQSRSYD 108
Query: 435 FEFANVEKPYEVYTGSNVRLRYFLR 509
FEF VEKPYE Y G+NVRLRYFL+
Sbjct: 109 FEFMQVEKPYESYIGANVRLRYFLK 133
Score = 127 bits (307), Expect = 4e-29
Identities = 61/75 (81%), Positives = 64/75 (85%)
Frame = +2
Query: 500 FPAATIVRCLTDITKEVDIAVHTLCSYPDVLNSIKMEVGIEDCLHIEFEYNKSKYHLKDV 679
F TIVR LTD+ KE D+ VH L +YPDV NSIKMEVGIEDCLHIEFEYNKSKYHLKDV
Sbjct: 131 FLKVTIVRRLTDLVKEYDLIVHQLATYPDVNNSIKMEVGIEDCLHIEFEYNKSKYHLKDV 190
Query: 680 IVGKIYFLLVRIKNQ 724
IVGKIYFLLVRIK Q
Sbjct: 191 IVGKIYFLLVRIKIQ 205
Score = 61.3 bits (142), Expect = 4e-09
Identities = 29/51 (56%), Positives = 38/51 (74%), Gaps = 2/51 (3%)
Frame = +1
Query: 118 MSFFG--FGQTADIEIVFDDADKRKVAEVKTDDGKKEKLLLYYDGETVPGK 264
MSF G FG +I+IV +D + RK+AE+KT+DGK EK L+YDGE+V GK
Sbjct: 1 MSFLGGFFGPICEIDIVLNDGETRKMAEMKTEDGKVEKHYLFYDGESVSGK 51
>AL596223-4|CAH71501.1| 327|Homo sapiens vacuolar protein sorting
26 homolog A (S. pombe) protein.
Length = 327
Score = 128 bits (310), Expect = 2e-29
Identities = 56/85 (65%), Positives = 69/85 (81%)
Frame = +3
Query: 255 SGKVNVTLRKPGSKLEHQGIKVELIGQIELFYDRGNHHEFISLVKELARPGDLLQHTSYP 434
SGKVN+ ++PG +LEHQGI++E +GQIELF D+ N HEF++LVKELA PG+L Q SY
Sbjct: 49 SGKVNLAFKQPGKRLEHQGIRIEFVGQIELFNDKSNTHEFVNLVKELALPGELTQSRSYD 108
Query: 435 FEFANVEKPYEVYTGSNVRLRYFLR 509
FEF VEKPYE Y G+NVRLRYFL+
Sbjct: 109 FEFMQVEKPYESYIGANVRLRYFLK 133
Score = 127 bits (307), Expect = 4e-29
Identities = 61/75 (81%), Positives = 64/75 (85%)
Frame = +2
Query: 500 FPAATIVRCLTDITKEVDIAVHTLCSYPDVLNSIKMEVGIEDCLHIEFEYNKSKYHLKDV 679
F TIVR LTD+ KE D+ VH L +YPDV NSIKMEVGIEDCLHIEFEYNKSKYHLKDV
Sbjct: 131 FLKVTIVRRLTDLVKEYDLIVHQLATYPDVNNSIKMEVGIEDCLHIEFEYNKSKYHLKDV 190
Query: 680 IVGKIYFLLVRIKNQ 724
IVGKIYFLLVRIK Q
Sbjct: 191 IVGKIYFLLVRIKIQ 205
Score = 61.3 bits (142), Expect = 4e-09
Identities = 29/51 (56%), Positives = 38/51 (74%), Gaps = 2/51 (3%)
Frame = +1
Query: 118 MSFFG--FGQTADIEIVFDDADKRKVAEVKTDDGKKEKLLLYYDGETVPGK 264
MSF G FG +I+IV +D + RK+AE+KT+DGK EK L+YDGE+V GK
Sbjct: 1 MSFLGGFFGPICEIDIVLNDGETRKMAEMKTEDGKVEKHYLFYDGESVSGK 51
>AL442635-2|CAH71779.1| 327|Homo sapiens vacuolar protein sorting
26 homolog A (S. pombe) protein.
Length = 327
Score = 128 bits (310), Expect = 2e-29
Identities = 56/85 (65%), Positives = 69/85 (81%)
Frame = +3
Query: 255 SGKVNVTLRKPGSKLEHQGIKVELIGQIELFYDRGNHHEFISLVKELARPGDLLQHTSYP 434
SGKVN+ ++PG +LEHQGI++E +GQIELF D+ N HEF++LVKELA PG+L Q SY
Sbjct: 49 SGKVNLAFKQPGKRLEHQGIRIEFVGQIELFNDKSNTHEFVNLVKELALPGELTQSRSYD 108
Query: 435 FEFANVEKPYEVYTGSNVRLRYFLR 509
FEF VEKPYE Y G+NVRLRYFL+
Sbjct: 109 FEFMQVEKPYESYIGANVRLRYFLK 133
Score = 127 bits (307), Expect = 4e-29
Identities = 61/75 (81%), Positives = 64/75 (85%)
Frame = +2
Query: 500 FPAATIVRCLTDITKEVDIAVHTLCSYPDVLNSIKMEVGIEDCLHIEFEYNKSKYHLKDV 679
F TIVR LTD+ KE D+ VH L +YPDV NSIKMEVGIEDCLHIEFEYNKSKYHLKDV
Sbjct: 131 FLKVTIVRRLTDLVKEYDLIVHQLATYPDVNNSIKMEVGIEDCLHIEFEYNKSKYHLKDV 190
Query: 680 IVGKIYFLLVRIKNQ 724
IVGKIYFLLVRIK Q
Sbjct: 191 IVGKIYFLLVRIKIQ 205
Score = 61.3 bits (142), Expect = 4e-09
Identities = 29/51 (56%), Positives = 38/51 (74%), Gaps = 2/51 (3%)
Frame = +1
Query: 118 MSFFG--FGQTADIEIVFDDADKRKVAEVKTDDGKKEKLLLYYDGETVPGK 264
MSF G FG +I+IV +D + RK+AE+KT+DGK EK L+YDGE+V GK
Sbjct: 1 MSFLGGFFGPICEIDIVLNDGETRKMAEMKTEDGKVEKHYLFYDGESVSGK 51
>AF175266-1|AAF89954.1| 327|Homo sapiens vacuolar sorting protein
26 protein.
Length = 327
Score = 128 bits (310), Expect = 2e-29
Identities = 56/85 (65%), Positives = 69/85 (81%)
Frame = +3
Query: 255 SGKVNVTLRKPGSKLEHQGIKVELIGQIELFYDRGNHHEFISLVKELARPGDLLQHTSYP 434
SGKVN+ ++PG +LEHQGI++E +GQIELF D+ N HEF++LVKELA PG+L Q SY
Sbjct: 49 SGKVNLAFKQPGKRLEHQGIRIEFVGQIELFNDKSNTHEFVNLVKELALPGELTQSRSYD 108
Query: 435 FEFANVEKPYEVYTGSNVRLRYFLR 509
FEF VEKPYE Y G+NVRLRYFL+
Sbjct: 109 FEFMQVEKPYESYIGANVRLRYFLK 133
Score = 127 bits (307), Expect = 4e-29
Identities = 61/75 (81%), Positives = 64/75 (85%)
Frame = +2
Query: 500 FPAATIVRCLTDITKEVDIAVHTLCSYPDVLNSIKMEVGIEDCLHIEFEYNKSKYHLKDV 679
F TIVR LTD+ KE D+ VH L +YPDV NSIKMEVGIEDCLHIEFEYNKSKYHLKDV
Sbjct: 131 FLKVTIVRRLTDLVKEYDLIVHQLATYPDVNNSIKMEVGIEDCLHIEFEYNKSKYHLKDV 190
Query: 680 IVGKIYFLLVRIKNQ 724
IVGKIYFLLVRIK Q
Sbjct: 191 IVGKIYFLLVRIKIQ 205
Score = 61.3 bits (142), Expect = 4e-09
Identities = 29/51 (56%), Positives = 38/51 (74%), Gaps = 2/51 (3%)
Frame = +1
Query: 118 MSFFG--FGQTADIEIVFDDADKRKVAEVKTDDGKKEKLLLYYDGETVPGK 264
MSF G FG +I+IV +D + RK+AE+KT+DGK EK L+YDGE+V GK
Sbjct: 1 MSFLGGFFGPICEIDIVLNDGETRKMAEMKTEDGKVEKHYLFYDGESVSGK 51
>AK022992-1|BAB14351.1| 327|Homo sapiens protein ( Homo sapiens
cDNA FLJ12930 fis, clone NT2RP2004816, highly similar to
H58 PROTEIN. ).
Length = 327
Score = 127 bits (307), Expect = 4e-29
Identities = 61/75 (81%), Positives = 64/75 (85%)
Frame = +2
Query: 500 FPAATIVRCLTDITKEVDIAVHTLCSYPDVLNSIKMEVGIEDCLHIEFEYNKSKYHLKDV 679
F TIVR LTD+ KE D+ VH L +YPDV NSIKMEVGIEDCLHIEFEYNKSKYHLKDV
Sbjct: 131 FLKVTIVRRLTDLVKEYDLIVHQLATYPDVNNSIKMEVGIEDCLHIEFEYNKSKYHLKDV 190
Query: 680 IVGKIYFLLVRIKNQ 724
IVGKIYFLLVRIK Q
Sbjct: 191 IVGKIYFLLVRIKIQ 205
Score = 127 bits (306), Expect = 5e-29
Identities = 55/85 (64%), Positives = 69/85 (81%)
Frame = +3
Query: 255 SGKVNVTLRKPGSKLEHQGIKVELIGQIELFYDRGNHHEFISLVKELARPGDLLQHTSYP 434
SGKVN+ ++PG +LEHQGI++E +G+IELF D+ N HEF++LVKELA PG+L Q SY
Sbjct: 49 SGKVNLAFKQPGKRLEHQGIRIEFVGRIELFNDKSNTHEFVNLVKELALPGELTQSRSYD 108
Query: 435 FEFANVEKPYEVYTGSNVRLRYFLR 509
FEF VEKPYE Y G+NVRLRYFL+
Sbjct: 109 FEFMQVEKPYESYIGANVRLRYFLK 133
Score = 61.3 bits (142), Expect = 4e-09
Identities = 29/51 (56%), Positives = 38/51 (74%), Gaps = 2/51 (3%)
Frame = +1
Query: 118 MSFFG--FGQTADIEIVFDDADKRKVAEVKTDDGKKEKLLLYYDGETVPGK 264
MSF G FG +I+IV +D + RK+AE+KT+DGK EK L+YDGE+V GK
Sbjct: 1 MSFLGGFFGPICEIDIVLNDGETRKMAEMKTEDGKVEKHYLFYDGESVSGK 51
>D87343-1|BAA23225.1| 297|Homo sapiens DCRA protein.
Length = 297
Score = 31.5 bits (68), Expect = 3.3
Identities = 22/71 (30%), Positives = 32/71 (45%), Gaps = 5/71 (7%)
Frame = +3
Query: 312 IKVELIGQIELFYDRGNHHEFISLVKELARPGDLLQ-HTSYPFEFANVEKP----YEVYT 476
+ + +G E FY+ + I+ E+ +PG T PFEF K YE Y
Sbjct: 51 LSAKSVGVFEAFYNSVKPIQIINSTIEMVKPGKFPSGKTEIPFEFPLHLKGNKVLYETYH 110
Query: 477 GSNVRLRYFLR 509
G V ++Y LR
Sbjct: 111 GVFVNIQYTLR 121
>BC110655-1|AAI10656.1| 297|Homo sapiens Down syndrome critical
region gene 3 protein.
Length = 297
Score = 31.5 bits (68), Expect = 3.3
Identities = 22/71 (30%), Positives = 32/71 (45%), Gaps = 5/71 (7%)
Frame = +3
Query: 312 IKVELIGQIELFYDRGNHHEFISLVKELARPGDLLQ-HTSYPFEFANVEKP----YEVYT 476
+ + +G E FY+ + I+ E+ +PG T PFEF K YE Y
Sbjct: 51 LSAKSVGVFEAFYNSVKPIQIINSTIEMVKPGKFPSGKTEIPFEFPLHLKGNKVLYETYH 110
Query: 477 GSNVRLRYFLR 509
G V ++Y LR
Sbjct: 111 GVFVNIQYTLR 121
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 109,015,300
Number of Sequences: 237096
Number of extensions: 2329774
Number of successful extensions: 4496
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4267
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4496
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8959138240
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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