Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= NV021855
(785 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P53675 Cluster: Clathrin heavy chain 2; n=87; Eukaryota... 233 5e-60
UniRef50_Q00610 Cluster: Clathrin heavy chain 1; n=54; Eukaryota... 231 1e-59
UniRef50_Q4S928 Cluster: Chromosome undetermined SCAF14702, whol... 212 1e-53
UniRef50_P22137 Cluster: Clathrin heavy chain; n=13; Ascomycota|... 175 1e-42
UniRef50_A6R3L7 Cluster: Clathrin heavy chain; n=1; Ajellomyces ... 169 7e-41
UniRef50_A2EV07 Cluster: Clathrin and VPS domain-containing prot... 156 5e-37
UniRef50_Q38KF8 Cluster: Chc1p; n=3; Oligohymenophorea|Rep: Chc1... 133 4e-30
UniRef50_A0CHK3 Cluster: Chromosome undetermined scaffold_182, w... 118 2e-25
UniRef50_Q8I5L6 Cluster: Clathrin heavy chain, putative; n=10; E... 109 8e-23
UniRef50_A5JZZ8 Cluster: Clathrin heavy chain, putative; n=2; Pl... 108 1e-22
UniRef50_Q1EQ28 Cluster: Clathrin heavy chain; n=4; cellular org... 100 4e-20
UniRef50_Q5CW85 Cluster: Clathrin heavy chain; n=2; Cryptosporid... 90 7e-17
UniRef50_Q4Q1R2 Cluster: Clathrin heavy chain, putative; n=10; E... 85 1e-15
UniRef50_A2GL34 Cluster: Clathrin and VPS domain-containing prot... 83 1e-14
UniRef50_Q4MZN7 Cluster: Clathrin heavy chain, putative; n=1; Th... 62 1e-08
UniRef50_Q7QTC4 Cluster: GLP_9_31364_35911; n=3; Giardia intesti... 60 6e-08
UniRef50_Q4UBV3 Cluster: Clathrin heavy chain, putative; n=1; Th... 58 2e-07
UniRef50_A7AVF3 Cluster: Clathrin heavy chain; n=1; Babesia bovi... 58 3e-07
UniRef50_Q4T6Z2 Cluster: Chromosome undetermined SCAF8478, whole... 53 9e-06
UniRef50_Q4TE15 Cluster: Chromosome 7 SCAF5879, whole genome sho... 42 0.018
UniRef50_Q54TN3 Cluster: Putative uncharacterized protein; n=1; ... 39 0.16
UniRef50_A7B3Y3 Cluster: Putative uncharacterized protein; n=1; ... 38 0.22
UniRef50_A0TJ86 Cluster: Putative uncharacterized protein; n=1; ... 33 8.1
>UniRef50_P53675 Cluster: Clathrin heavy chain 2; n=87; Eukaryota|Rep:
Clathrin heavy chain 2 - Homo sapiens (Human)
Length = 1640
Score = 233 bits (569), Expect = 5e-60
Identities = 119/173 (68%), Positives = 128/173 (73%)
Frame = +3
Query: 255 LISLLEAALGLERAHMGMFTELAILYSKYKPVKMREHLELFWSRVNIPKVLRAAEHAHLW 434
LI LLEAALGLERAHMGMFTELAILYSK+KP KM EHLELFWSRVNIPKVLRAAE AHLW
Sbjct: 1299 LILLLEAALGLERAHMGMFTELAILYSKFKPQKMLEHLELFWSRVNIPKVLRAAEQAHLW 1358
Query: 435 SELVFLYDKYEEYDNAALTMMQHPTRLGARDTSKT*SLKSRTWNCTTKLSNFT*TTSHFL 614
+ELVFLYDKYEEYDNA LTMM HPT K K + F L
Sbjct: 1359 AELVFLYDKYEEYDNAVLTMMSHPTEAWKEGQFKDIITKVANVELCYRALQFYLDYKPLL 1418
Query: 615 LNDLLLVLAPRMDHTRAVNFFTKAGHLQLVKAYLRSVQSLNNKAVNEALTRCL 773
+NDLLLVL+PR+DHT V+FF+KAG L LVK YLRSVQS NNK+VNEAL L
Sbjct: 1419 INDLLLVLSPRLDHTWTVSFFSKAGQLPLVKPYLRSVQSHNNKSVNEALNHLL 1471
Score = 148 bits (359), Expect = 1e-34
Identities = 65/85 (76%), Positives = 78/85 (91%)
Frame = +1
Query: 1 AKLLYNNVSNFARLAITLVHLKEFQGAVDSARKANSTRTWKEVCFACVDAGEFRLAQMCG 180
AKLLY+NVSNFARLA TLVHL E+Q AVD++RKA+STRTWKEVCFAC+D EFR AQ+CG
Sbjct: 1214 AKLLYSNVSNFARLASTLVHLGEYQAAVDNSRKASSTRTWKEVCFACMDGQEFRFAQLCG 1273
Query: 181 LHIVVHADELEDLINYYQDRGHFDD 255
LHIV+HADELE+L+ YYQDRG+F++
Sbjct: 1274 LHIVIHADELEELMCYYQDRGYFEE 1298
>UniRef50_Q00610 Cluster: Clathrin heavy chain 1; n=54; Eukaryota|Rep:
Clathrin heavy chain 1 - Homo sapiens (Human)
Length = 1675
Score = 231 bits (565), Expect = 1e-59
Identities = 115/174 (66%), Positives = 130/174 (74%)
Frame = +3
Query: 255 LISLLEAALGLERAHMGMFTELAILYSKYKPVKMREHLELFWSRVNIPKVLRAAEHAHLW 434
LI++LEAALGLERAHMGMFTELAILYSK+KP KMREHLELFWSRVNIPKVLRAAE AHLW
Sbjct: 1299 LITMLEAALGLERAHMGMFTELAILYSKFKPQKMREHLELFWSRVNIPKVLRAAEQAHLW 1358
Query: 435 SELVFLYDKYEEYDNAALTMMQHPTRLGARDTSKT*SLKSRTWNCTTKLSNFT*TTSHFL 614
+ELVFLYDKYEEYDNA +TMM HPT K K + F L
Sbjct: 1359 AELVFLYDKYEEYDNAIITMMNHPTDAWKEGQFKDIITKVANVELYYRAIQFYLEFKPLL 1418
Query: 615 LNDLLLVLAPRMDHTRAVNFFTKAGHLQLVKAYLRSVQSLNNKAVNEALTRCLL 776
LNDLL+VL+PR+DHTRAVN+F+K L LVK YLRSVQ+ NNK+VNE+L +
Sbjct: 1419 LNDLLMVLSPRLDHTRAVNYFSKVKQLPLVKPYLRSVQNHNNKSVNESLNNLFI 1472
Score = 161 bits (390), Expect = 2e-38
Identities = 73/85 (85%), Positives = 78/85 (91%)
Frame = +1
Query: 1 AKLLYNNVSNFARLAITLVHLKEFQGAVDSARKANSTRTWKEVCFACVDAGEFRLAQMCG 180
AKLLYNNVSNF RLA TLVHL E+Q AVD ARKANSTRTWKEVCFACVD EFRLAQMCG
Sbjct: 1214 AKLLYNNVSNFGRLASTLVHLGEYQAAVDGARKANSTRTWKEVCFACVDGKEFRLAQMCG 1273
Query: 181 LHIVVHADELEDLINYYQDRGHFDD 255
LHIVVHADELE+LINYYQDRG+F++
Sbjct: 1274 LHIVVHADELEELINYYQDRGYFEE 1298
>UniRef50_Q4S928 Cluster: Chromosome undetermined SCAF14702, whole
genome shotgun sequence; n=4; Eumetazoa|Rep: Chromosome
undetermined SCAF14702, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1909
Score = 212 bits (517), Expect = 1e-53
Identities = 118/201 (58%), Positives = 131/201 (65%), Gaps = 26/201 (12%)
Frame = +3
Query: 255 LISLLEAALGLERAHMGMFTELAILYSKYKPVKMREHLELFWSRVNIPKVLRAAEHAHLW 434
LI++LEAALGLERAHMGMFTELAILYSK+KP KMREHLELFWSRVNIPKVLRAAE AHLW
Sbjct: 1490 LITMLEAALGLERAHMGMFTELAILYSKFKPQKMREHLELFWSRVNIPKVLRAAEQAHLW 1549
Query: 435 SELVFLYDKYEEYDNAALTMMQHPTRLGARDTSKT*SLKSRTWNCTTKLSNFT*TTSHFL 614
ELVFLYDKYEEYDNA +TMM HP K K K +F L
Sbjct: 1550 GELVFLYDKYEEYDNAIITMMSHPADAWKEGQFKDIVTKVANVELYYKAVHFYLEFKPLL 1609
Query: 615 LNDLLLVLAPRMDHTRAVNFFTKAG--------------------------HLQLVKAYL 716
LNDLL+VL+PR+DHTRAVNFF+K G L LVK YL
Sbjct: 1610 LNDLLIVLSPRLDHTRAVNFFSKVGLLLLILLLLLLLPLLSCWPCACVQVKQLPLVKPYL 1669
Query: 717 RSVQSLNNKAVNEALTRCLLM 779
RSVQ+ NNK+VNEAL ++
Sbjct: 1670 RSVQNHNNKSVNEALNNLFII 1690
Score = 89.0 bits (211), Expect = 1e-16
Identities = 37/44 (84%), Positives = 42/44 (95%)
Frame = +1
Query: 124 EVCFACVDAGEFRLAQMCGLHIVVHADELEDLINYYQDRGHFDD 255
+VCFACVD EFRLAQMCGLHIVVHADELE+LINYYQDRG+F++
Sbjct: 1446 QVCFACVDGKEFRLAQMCGLHIVVHADELEELINYYQDRGYFEE 1489
Score = 37.5 bits (83), Expect = 0.38
Identities = 25/55 (45%), Positives = 27/55 (49%), Gaps = 5/55 (9%)
Frame = +2
Query: 2 RNSCITTSATSPVLLLL---WCI*KNFKVPWTARVRPTLRAHGRR--SASRAWTP 151
R SC TT T P L WC + + PWT RPT RA GRR A R TP
Sbjct: 1373 RPSCSTT--TCPTLAAWPPPWCTWGSTRPPWTELARPTARAPGRRWAGARRGCTP 1425
>UniRef50_P22137 Cluster: Clathrin heavy chain; n=13; Ascomycota|Rep:
Clathrin heavy chain - Saccharomyces cerevisiae (Baker's
yeast)
Length = 1653
Score = 175 bits (426), Expect = 1e-42
Identities = 93/168 (55%), Positives = 112/168 (66%)
Frame = +3
Query: 255 LISLLEAALGLERAHMGMFTELAILYSKYKPVKMREHLELFWSRVNIPKVLRAAEHAHLW 434
LISL EA LGLERAHMGMFTELAILYSKY+P K EHL+LFWSR+NIPKV+RA E AHLW
Sbjct: 1305 LISLFEAGLGLERAHMGMFTELAILYSKYEPDKTFEHLKLFWSRINIPKVIRAVEQAHLW 1364
Query: 435 SELVFLYDKYEEYDNAALTMMQHPTRLGARDTSKT*SLKSRTWNCTTKLSNFT*TTSHFL 614
SELVFLY Y+E+DNAALT+++ T+ K +K K NF L
Sbjct: 1365 SELVFLYAHYDEWDNAALTLIEKSTKDLDHAYFKEVVVKVSNLEIYYKAINFYVKFHPSL 1424
Query: 615 LNDLLLVLAPRMDHTRAVNFFTKAGHLQLVKAYLRSVQSLNNKAVNEA 758
L DLL L PR+D R V F+K+ +L L+K +L +V NN VN+A
Sbjct: 1425 LVDLLTSLTPRLDIPRTVKIFSKSDNLPLIKPFLINVLPKNNSVVNQA 1472
Score = 102 bits (245), Expect = 9e-21
Identities = 42/85 (49%), Positives = 69/85 (81%)
Frame = +1
Query: 1 AKLLYNNVSNFARLAITLVHLKEFQGAVDSARKANSTRTWKEVCFACVDAGEFRLAQMCG 180
A+L Y+ VSN+++LA TLV+L ++Q AVD+ARKA++ + WK V AC++ EF+LAQ+CG
Sbjct: 1220 ARLCYSAVSNYSKLASTLVYLGDYQAAVDTARKASNIKVWKLVNDACIEKKEFKLAQICG 1279
Query: 181 LHIVVHADELEDLINYYQDRGHFDD 255
L+++VHA+EL++L+ Y+ G+F++
Sbjct: 1280 LNLIVHAEELDELVERYESNGYFEE 1304
>UniRef50_A6R3L7 Cluster: Clathrin heavy chain; n=1; Ajellomyces
capsulatus NAm1|Rep: Clathrin heavy chain - Ajellomyces
capsulatus NAm1
Length = 1631
Score = 169 bits (411), Expect = 7e-41
Identities = 87/174 (50%), Positives = 111/174 (63%)
Frame = +3
Query: 255 LISLLEAALGLERAHMGMFTELAILYSKYKPVKMREHLELFWSRVNIPKVLRAAEHAHLW 434
LI++LEA LGLERAHMGMFTEL I SKY P K+ EHL+LFW+R+NIPK++RA E A+LW
Sbjct: 1254 LIAVLEAGLGLERAHMGMFTELGISLSKYHPDKVMEHLKLFWTRINIPKMIRACEEANLW 1313
Query: 435 SELVFLYDKYEEYDNAALTMMQHPTRLGARDTSKT*SLKSRTWNCTTKLSNFT*TTSHFL 614
ELVFLY Y+E+DNAAL MM+ + K +K + NF L
Sbjct: 1314 PELVFLYCHYDEWDNAALAMMERAADSWEHHSFKDIIVKVANLEIYYRALNFYLQEQPLL 1373
Query: 615 LNDLLLVLAPRMDHTRAVNFFTKAGHLQLVKAYLRSVQSLNNKAVNEALTRCLL 776
L DLL VL PR+D R V F K+ ++ L+K +L +VQ N KAVN A+ L+
Sbjct: 1374 LTDLLQVLTPRIDVNRVVRMFEKSDNIPLIKPFLLNVQPQNKKAVNNAINDLLI 1427
Score = 115 bits (276), Expect = 2e-24
Identities = 48/85 (56%), Positives = 70/85 (82%)
Frame = +1
Query: 1 AKLLYNNVSNFARLAITLVHLKEFQGAVDSARKANSTRTWKEVCFACVDAGEFRLAQMCG 180
AK+ Y ++SN+A+LA TLVHL+E+Q AV+ ARKAN+ + WK+V ACV EFRLAQ+CG
Sbjct: 1169 AKIFYTSISNWAKLATTLVHLEEYQAAVECARKANNIKVWKQVNEACVSKKEFRLAQICG 1228
Query: 181 LHIVVHADELEDLINYYQDRGHFDD 255
L+++VHA+EL+DL++ Y+ G+FD+
Sbjct: 1229 LNLIVHAEELQDLVHQYERNGYFDE 1253
>UniRef50_A2EV07 Cluster: Clathrin and VPS domain-containing
protein; n=4; Trichomonas vaginalis G3|Rep: Clathrin and
VPS domain-containing protein - Trichomonas vaginalis G3
Length = 614
Score = 156 bits (379), Expect = 5e-37
Identities = 76/172 (44%), Positives = 113/172 (65%)
Frame = +3
Query: 252 RLISLLEAALGLERAHMGMFTELAILYSKYKPVKMREHLELFWSRVNIPKVLRAAEHAHL 431
++I LLEAALGLERAH G+FTELA+LY+K++P K +HL+ F R+ + KV++ + H+
Sbjct: 215 QVIGLLEAALGLERAHGGIFTELAVLYAKHQPEKCMDHLKQFNQRIALFKVIKILQAMHM 274
Query: 432 WSELVFLYDKYEEYDNAALTMMQHPTRLGARDTSKT*SLKSRTWNCTTKLSNFT*TTSHF 611
W EL + YDKY E+DNA T+++HP+ + K + + + NF T S
Sbjct: 275 WKELTYAYDKYSEFDNAVTTIIEHPSAAWTHNYFKELVAQVSNADILYRSLNFYLTISPM 334
Query: 612 LLNDLLLVLAPRMDHTRAVNFFTKAGHLQLVKAYLRSVQSLNNKAVNEALTR 767
+ DLL + P++D TR V+ F ++ +LQL+K+YL S+QS N +AVNEAL R
Sbjct: 335 DIPDLLQTIGPKIDSTRLVDMFKRSNNLQLIKSYLASIQSTNVQAVNEALNR 386
Score = 100 bits (240), Expect = 4e-20
Identities = 44/83 (53%), Positives = 64/83 (77%)
Frame = +1
Query: 1 AKLLYNNVSNFARLAITLVHLKEFQGAVDSARKANSTRTWKEVCFACVDAGEFRLAQMCG 180
AK+LY+ V ++ARLA TL+ LKE Q A+D+ARKA+ST++W V AC++ G+F+LAQ+ G
Sbjct: 131 AKILYSAVKDYARLAETLIELKELQAAIDAARKASSTKSWMAVLRACIEIGDFKLAQVAG 190
Query: 181 LHIVVHADELEDLINYYQDRGHF 249
L IV+ AD L ++I Y+D G+F
Sbjct: 191 LQIVIEADHLLEVIKLYEDGGYF 213
>UniRef50_Q38KF8 Cluster: Chc1p; n=3; Oligohymenophorea|Rep: Chc1p -
Tetrahymena thermophila
Length = 636
Score = 133 bits (322), Expect = 4e-30
Identities = 66/174 (37%), Positives = 104/174 (59%)
Frame = +3
Query: 255 LISLLEAALGLERAHMGMFTELAILYSKYKPVKMREHLELFWSRVNIPKVLRAAEHAHLW 434
+ISLLE +GL+RAH+G+FTEL +L +KY+P ++ EH + ++S++NI K+LR E W
Sbjct: 226 MISLLETGMGLDRAHVGIFTELGVLLAKYRPERLMEHCKQYYSKMNISKLLRVCERYQHW 285
Query: 435 SELVFLYDKYEEYDNAALTMMQHPTRLGARDTSKT*SLKSRTWNCTTKLSNFT*TTSHFL 614
SE VFL+ Y++YDNA M++H D +K+ ++ K F
Sbjct: 286 SEAVFLHSNYDQYDNAINIMIEHSPVAFNHDQFVNLLIKASNYDLYYKAILFYLDEQPEQ 345
Query: 615 LNDLLLVLAPRMDHTRAVNFFTKAGHLQLVKAYLRSVQSLNNKAVNEALTRCLL 776
+N+LL L ++D ++ V+ K G++ L+ +L+SVQ+ NNK VNE L L
Sbjct: 346 VNELLRSLTTKIDLSKCVSVMRKTGYIALITPFLKSVQNANNKEVNEILNEIYL 399
Score = 99.5 bits (237), Expect = 8e-20
Identities = 42/85 (49%), Positives = 64/85 (75%)
Frame = +1
Query: 1 AKLLYNNVSNFARLAITLVHLKEFQGAVDSARKANSTRTWKEVCFACVDAGEFRLAQMCG 180
AKLL+ N A++A LV LK+FQ A+D+A+KAN+ +TWKE+ ACV+A EF+LA + G
Sbjct: 141 AKLLFTATKNNAKIASCLVRLKQFQQAIDAAKKANTPKTWKELTMACVEAAEFKLAAVAG 200
Query: 181 LHIVVHADELEDLINYYQDRGHFDD 255
L+I++H D LE+L YY++ G+ ++
Sbjct: 201 LNIIIHPDHLEELAQYYEEFGYSNE 225
>UniRef50_A0CHK3 Cluster: Chromosome undetermined scaffold_182, whole
genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_182, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 1690
Score = 118 bits (284), Expect = 2e-25
Identities = 64/174 (36%), Positives = 97/174 (55%)
Frame = +3
Query: 255 LISLLEAALGLERAHMGMFTELAILYSKYKPVKMREHLELFWSRVNIPKVLRAAEHAHLW 434
++ LLE ALG++RAH+G+FTELA+LY YK K+ EH ++ ++NI KVLR E LW
Sbjct: 1294 MMILLENALGMQRAHVGIFTELAVLYCHYKQKKVMEHCRQYFQKMNILKVLRTCEKMCLW 1353
Query: 435 SELVFLYDKYEEYDNAALTMMQHPTRLGARDTSKT*SLKSRTWNCTTKLSNFT*TTSHFL 614
SE V+L+ Y++ DNA M++H + D K + K F
Sbjct: 1354 SEAVYLHQHYDQPDNAINIMIEHSPTAFSHDVLVMLLQKITNTDLYYKCILFYLEEQPEQ 1413
Query: 615 LNDLLLVLAPRMDHTRAVNFFTKAGHLQLVKAYLRSVQSLNNKAVNEALTRCLL 776
+NDLL + ++D ++ V G+L L +L+ +Q+ NNK VN+AL + L
Sbjct: 1414 INDLLRSIQSKIDLSKFVKLMKNTGYLALTLPFLQQIQNANNKDVNDALNQLYL 1467
Score = 87.4 bits (207), Expect = 4e-16
Identities = 37/79 (46%), Positives = 58/79 (73%)
Frame = +1
Query: 1 AKLLYNNVSNFARLAITLVHLKEFQGAVDSARKANSTRTWKEVCFACVDAGEFRLAQMCG 180
AK+L+ + N AR+A LV LK+F A+++A+KAN+++TWKE+CFACV+A EF+ A +
Sbjct: 1209 AKILFTALKNNARIASCLVRLKQFNKAIEAAQKANTSKTWKELCFACVEASEFKYASIAA 1268
Query: 181 LHIVVHADELEDLINYYQD 237
+I++ D LE LI Y++
Sbjct: 1269 QNIIIVPDMLESLIKQYEE 1287
>UniRef50_Q8I5L6 Cluster: Clathrin heavy chain, putative; n=10;
Eukaryota|Rep: Clathrin heavy chain, putative -
Plasmodium falciparum (isolate 3D7)
Length = 1997
Score = 109 bits (262), Expect = 8e-23
Identities = 61/174 (35%), Positives = 97/174 (55%)
Frame = +3
Query: 255 LISLLEAALGLERAHMGMFTELAILYSKYKPVKMREHLELFWSRVNIPKVLRAAEHAHLW 434
L++LLE L ERAH+G++TEL ILY+KYKP K+ E + + +++N K++ E+ +L
Sbjct: 1620 LMNLLENGLNNERAHVGIYTELGILYAKYKPEKLMEFIRNYTNKMNTRKLIDVCENEYLL 1679
Query: 435 SELVFLYDKYEEYDNAALTMMQHPTRLGARDTSKT*SLKSRTWNCTTKLSNFT*TTSHFL 614
E V+LY Y+EY+ A T+++H DT K + K+ +F
Sbjct: 1680 KEAVYLYISYDEYNLAVDTIIKHSPTAYTADTFMQVIHKVTNSDIIHKVIDFYIEEHPLN 1739
Query: 615 LNDLLLVLAPRMDHTRAVNFFTKAGHLQLVKAYLRSVQSLNNKAVNEALTRCLL 776
L +LL +L ++D+ R V K+ +L L++ YL +Q+ N AVNE L L
Sbjct: 1740 LYNLLKILENKIDNNRLVQTLKKSNNLPLIQKYLEDIQAQNITAVNETLNEIYL 1793
Score = 78.2 bits (184), Expect = 2e-13
Identities = 32/85 (37%), Positives = 56/85 (65%)
Frame = +1
Query: 1 AKLLYNNVSNFARLAITLVHLKEFQGAVDSARKANSTRTWKEVCFACVDAGEFRLAQMCG 180
AK+LY+N+ N +L + LKE+ A+++A+KA S +TWKEV F CV + + A G
Sbjct: 1535 AKILYSNIPNNQKLTACYLKLKEYALAIEAAKKAKSLKTWKEVNFICVKYKQLKYAHTAG 1594
Query: 181 LHIVVHADELEDLINYYQDRGHFDD 255
L +++HAD L+++I Y+ + + ++
Sbjct: 1595 LQLIMHADHLDEIIKIYEKKKYINE 1619
>UniRef50_A5JZZ8 Cluster: Clathrin heavy chain, putative; n=2;
Plasmodium|Rep: Clathrin heavy chain, putative -
Plasmodium vivax
Length = 1935
Score = 108 bits (260), Expect = 1e-22
Identities = 61/174 (35%), Positives = 96/174 (55%)
Frame = +3
Query: 255 LISLLEAALGLERAHMGMFTELAILYSKYKPVKMREHLELFWSRVNIPKVLRAAEHAHLW 434
L+SLLE L ERAH+G++TEL ILY+KYKP K+ E + + +++N K++ ++ +L
Sbjct: 1534 LMSLLENGLNSERAHVGIYTELGILYAKYKPEKLMEFIRNYSNKMNTRKLIDVCQNEYLL 1593
Query: 435 SELVFLYDKYEEYDNAALTMMQHPTRLGARDTSKT*SLKSRTWNCTTKLSNFT*TTSHFL 614
E V+LY Y+EY+ A T+++H DT K + K+ +F
Sbjct: 1594 KEAVYLYISYDEYNLAVDTIIKHSPTAYTPDTFMQVIHKVTNSDIIHKVIDFYIEEHPLN 1653
Query: 615 LNDLLLVLAPRMDHTRAVNFFTKAGHLQLVKAYLRSVQSLNNKAVNEALTRCLL 776
L +LL +L ++D+ R V K+ +L L++ YL +Q N AVNE L L
Sbjct: 1654 LYNLLKILENKIDNNRLVQTLKKSNNLPLIQKYLEDIQGQNITAVNETLNEIYL 1707
Score = 80.6 bits (190), Expect = 4e-14
Identities = 33/85 (38%), Positives = 57/85 (67%)
Frame = +1
Query: 1 AKLLYNNVSNFARLAITLVHLKEFQGAVDSARKANSTRTWKEVCFACVDAGEFRLAQMCG 180
AK+LY+N+ N +L + LKE+ A+++A+KA S +TWKEV F CV + + A G
Sbjct: 1449 AKILYSNIPNNQKLTFCYLKLKEYSLAIEAAKKAKSLKTWKEVNFICVKYKQLKHAHTAG 1508
Query: 181 LHIVVHADELEDLINYYQDRGHFDD 255
L +++HAD L+++IN Y+ + + ++
Sbjct: 1509 LQLIMHADHLDEIINIYEKKKYINE 1533
>UniRef50_Q1EQ28 Cluster: Clathrin heavy chain; n=4; cellular
organisms|Rep: Clathrin heavy chain - Entamoeba
histolytica
Length = 1622
Score = 100 bits (240), Expect = 4e-20
Identities = 57/170 (33%), Positives = 91/170 (53%)
Frame = +3
Query: 252 RLISLLEAALGLERAHMGMFTELAILYSKYKPVKMREHLELFWSRVNIPKVLRAAEHAHL 431
++I LLEA L +E H+ MFTELAILYSKYK K+ ++L+ + +++ KV+
Sbjct: 1230 QVIELLEAGLKIENVHVSMFTELAILYSKYKEEKLYDYLKQYVAKIQCQKVIPTVNMNQQ 1289
Query: 432 WSELVFLYDKYEEYDNAALTMMQHPTRLGARDTSKT*SLKSRTWNCTTKLSNFT*TTSHF 611
W ELVFLY + ++ A TM+ +P K + + K ++
Sbjct: 1290 WKELVFLYVQVDQV-KAIETMISYPDDCFDHQLMKELLVNVPRIDMIYKAESYYLAEKPE 1348
Query: 612 LLNDLLLVLAPRMDHTRAVNFFTKAGHLQLVKAYLRSVQSLNNKAVNEAL 761
+N++L+ +A R DHT+ ++ K L+ ++ YL LNN +VNEAL
Sbjct: 1349 KVNEMLIAVAHRCDHTQVISIARKEKDLKTIREYLLYCLDLNNDSVNEAL 1398
Score = 100 bits (239), Expect = 5e-20
Identities = 43/84 (51%), Positives = 65/84 (77%)
Frame = +1
Query: 1 AKLLYNNVSNFARLAITLVHLKEFQGAVDSARKANSTRTWKEVCFACVDAGEFRLAQMCG 180
AK+LY +++N+ +LA L+ LK++ GAV++A+KANSTRTWKEV FAC+DA EF LAQ G
Sbjct: 1146 AKILYTSLNNYIKLASCLLKLKDYAGAVEAAKKANSTRTWKEVTFACIDAKEFTLAQETG 1205
Query: 181 LHIVVHADELEDLINYYQDRGHFD 252
++I++ DE+ +L+ YY+ +D
Sbjct: 1206 INILMAGDEITELVYYYEKNELYD 1229
>UniRef50_Q5CW85 Cluster: Clathrin heavy chain; n=2;
Cryptosporidium|Rep: Clathrin heavy chain -
Cryptosporidium parvum Iowa II
Length = 2007
Score = 89.8 bits (213), Expect = 7e-17
Identities = 40/92 (43%), Positives = 61/92 (66%), Gaps = 1/92 (1%)
Frame = +3
Query: 255 LISLLEAAL-GLERAHMGMFTELAILYSKYKPVKMREHLELFWSRVNIPKVLRAAEHAHL 431
L++LLE A+ +RA+ +FTEL ILY+KY P K+ ++ + R+NIPK+ R E L
Sbjct: 1532 LLTLLEGAIQNTDRANGSLFTELGILYAKYTPEKLMDYCSSYSGRINIPKLTRICEQRQL 1591
Query: 432 WSELVFLYDKYEEYDNAALTMMQHPTRLGARD 527
W+E+V+LY +Y+E+D A LT++ HP D
Sbjct: 1592 WNEVVYLYLQYQEFDQAVLTVISHPKEAWKND 1623
Score = 74.5 bits (175), Expect = 3e-12
Identities = 30/79 (37%), Positives = 51/79 (64%)
Frame = +1
Query: 7 LLYNNVSNFARLAITLVHLKEFQGAVDSARKANSTRTWKEVCFACVDAGEFRLAQMCGLH 186
+ Y + N++RL + L E+ A+++A+KANS +TWKE+ C+ GE LA GL+
Sbjct: 1449 IFYQAIPNYSRLTSCYIQLGEYNNALETAKKANSPKTWKELLQICMQIGESELAHQAGLN 1508
Query: 187 IVVHADELEDLINYYQDRG 243
I+V+ D ED+++ Y+ +G
Sbjct: 1509 IIVYPDYCEDVVSEYEKKG 1527
Score = 35.5 bits (78), Expect = 1.5
Identities = 13/33 (39%), Positives = 20/33 (60%)
Frame = +2
Query: 509 EAWREGHFKDIITKVANMELYYKAIQFYLDYKP 607
EAW+ F I+ V N+++ YK++ FYL P
Sbjct: 1618 EAWKNDQFLSILQNVTNVDILYKSMTFYLQEHP 1650
>UniRef50_Q4Q1R2 Cluster: Clathrin heavy chain, putative; n=10;
Eukaryota|Rep: Clathrin heavy chain, putative -
Leishmania major
Length = 1680
Score = 85.4 bits (202), Expect = 1e-15
Identities = 52/169 (30%), Positives = 80/169 (47%)
Frame = +3
Query: 255 LISLLEAALGLERAHMGMFTELAILYSKYKPVKMREHLELFWSRVNIPKVLRAAEHAHLW 434
L S+L A + AHM +FTE+ +L +KY+P K+ EH+ ++ ++N K++ E H W
Sbjct: 1315 LFSVLRNASSHQGAHMSIFTEMGVLLAKYRPEKLMEHVIMYAKKINTHKMITVCEQYHHW 1374
Query: 435 SELVFLYDKYEEYDNAALTMMQHPTRLGARDTSKT*SLKSRTWNCTTKLSNFT*TTSHFL 614
L L+ E++ A +MMQH + K F T
Sbjct: 1375 VVLRVLHTNNEDWLAATNSMMQHHADAFDHEIFKDAVSHLGASELLYTAIGFYLKTHPDQ 1434
Query: 615 LNDLLLVLAPRMDHTRAVNFFTKAGHLQLVKAYLRSVQSLNNKAVNEAL 761
LND L + R+D R + TK + +++ YL + Q N K VNEAL
Sbjct: 1435 LNDFLSSIFKRVDPERVMAETTKVAPIHVIRTYLEAAQERNAKKVNEAL 1483
Score = 74.1 bits (174), Expect = 4e-12
Identities = 32/85 (37%), Positives = 56/85 (65%)
Frame = +1
Query: 1 AKLLYNNVSNFARLAITLVHLKEFQGAVDSARKANSTRTWKEVCFACVDAGEFRLAQMCG 180
A++LY +N+AR+A T V L AV++A+KA S +KE AC++AG+ +LA +C
Sbjct: 1230 ARVLYTVANNYARVASTEVMLNNLPAAVEAAKKAKSIHAYKEANLACIEAGDLKLAGVCA 1289
Query: 181 LHIVVHADELEDLINYYQDRGHFDD 255
+ +V+ A+E+ + N Y+ RG +++
Sbjct: 1290 VPVVLKAEEVSGMCNRYESRGLWEE 1314
>UniRef50_A2GL34 Cluster: Clathrin and VPS domain-containing
protein; n=1; Trichomonas vaginalis G3|Rep: Clathrin and
VPS domain-containing protein - Trichomonas vaginalis G3
Length = 838
Score = 82.6 bits (195), Expect = 1e-14
Identities = 36/65 (55%), Positives = 51/65 (78%)
Frame = +1
Query: 1 AKLLYNNVSNFARLAITLVHLKEFQGAVDSARKANSTRTWKEVCFACVDAGEFRLAQMCG 180
AK+LY V ++ARLA TL+ LKE Q A+D+ARKA+ST++W V AC++ G+F+LAQ+ G
Sbjct: 774 AKILYTAVKDYARLAETLIELKELQAAIDAARKASSTKSWMAVLRACIEIGDFKLAQVAG 833
Query: 181 LHIVV 195
L IV+
Sbjct: 834 LQIVI 838
>UniRef50_Q4MZN7 Cluster: Clathrin heavy chain, putative; n=1;
Theileria parva|Rep: Clathrin heavy chain, putative -
Theileria parva
Length = 1696
Score = 62.5 bits (145), Expect = 1e-08
Identities = 50/158 (31%), Positives = 70/158 (44%), Gaps = 3/158 (1%)
Frame = +3
Query: 312 TELAILYSKYKPVKMREHLE--LFWSR-VNIPKVLRAAEHAHLWSELVFLYDKYEEYDNA 482
TELAI +KY P + EHL F S +NI K R + LW E VFLY ++ D A
Sbjct: 1395 TELAICIAKYHPELLMEHLRNVAFESNSLNISKTARECSNLWLWKEAVFLY-TIDDSDKA 1453
Query: 483 ALTMMQHPTRLGARDTSKT*SLKSRTWNCTTKLSNFT*TTSHFLLNDLLLVLAPRMDHTR 662
L+M HP +T + S T K F L+ LLL + ++D R
Sbjct: 1454 ILSMTLHPECFEQDLFFRTLNNVSNT-EVIYKALYFCIQQYPTLVPKLLLCVRSKLDTGR 1512
Query: 663 AVNFFTKAGHLQLVKAYLRSVQSLNNKAVNEALTRCLL 776
+ +QL K Y + N++ VN+ L L+
Sbjct: 1513 VIKILKNNNCIQLAKEYFQQYSDRNSQLVNDTLYELLV 1550
>UniRef50_Q7QTC4 Cluster: GLP_9_31364_35911; n=3; Giardia
intestinalis|Rep: GLP_9_31364_35911 - Giardia lamblia
ATCC 50803
Length = 1515
Score = 60.1 bits (139), Expect = 6e-08
Identities = 27/85 (31%), Positives = 51/85 (60%)
Frame = +1
Query: 1 AKLLYNNVSNFARLAITLVHLKEFQGAVDSARKANSTRTWKEVCFACVDAGEFRLAQMCG 180
AK + V +++RL++TLV L+ + AV++A +A WK V C++ +F LA+
Sbjct: 1063 AKYFFEFVGDWSRLSLTLVKLRCLKEAVEAATRAADPECWKAVAAECLEIRDFELAKSVF 1122
Query: 181 LHIVVHADELEDLINYYQDRGHFDD 255
L++V+ EL ++ YY++ G ++
Sbjct: 1123 LNLVLVESELPSIVQYYEEYGFIEE 1147
Score = 46.0 bits (104), Expect = 0.001
Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 7/84 (8%)
Frame = +3
Query: 306 MFTELAILYSKYK-------PVKMREHLELFWSRVNIPKVLRAAEHAHLWSELVFLYDKY 464
+FT LAILY KY P +++ +++ ++++IP +L LW E +L
Sbjct: 1171 IFTILAILYCKYMWIVRKTDPQRLQTYIKTHGNKIHIPTLLHWTRETRLWGEYAYLLAAS 1230
Query: 465 EEYDNAALTMMQHPTRLGARDTSK 536
++D A + M+ HP D K
Sbjct: 1231 RDFDKAVVEMIAHPPSSFNHDVMK 1254
>UniRef50_Q4UBV3 Cluster: Clathrin heavy chain, putative; n=1;
Theileria annulata|Rep: Clathrin heavy chain, putative -
Theileria annulata
Length = 2068
Score = 58.0 bits (134), Expect = 2e-07
Identities = 48/153 (31%), Positives = 70/153 (45%), Gaps = 3/153 (1%)
Frame = +3
Query: 312 TELAILYSKYKPVKMREHLE--LFWSR-VNIPKVLRAAEHAHLWSELVFLYDKYEEYDNA 482
TELAI +KY P ++ EHL F S +NI K R + LW E VFLY ++ D A
Sbjct: 1771 TELAICIAKYHPEELMEHLRNVAFESNSLNISKTARECSNLWLWREAVFLY-TIDDSDKA 1829
Query: 483 ALTMMQHPTRLGARDTSKT*SLKSRTWNCTTKLSNFT*TTSHFLLNDLLLVLAPRMDHTR 662
L+M+ HP + +T + S T K F +N LL + ++D R
Sbjct: 1830 ILSMILHPECFEEQLFFRTLANVSNT-EVIYKALYFYIQQYPTAVNKLLSCVKFKLDTGR 1888
Query: 663 AVNFFTKAGHLQLVKAYLRSVQSLNNKAVNEAL 761
+ LQL K Y + N++ +N+ L
Sbjct: 1889 VIKILRNNNCLQLAKEYFQQ-SDRNSQQINDTL 1920
>UniRef50_A7AVF3 Cluster: Clathrin heavy chain; n=1; Babesia
bovis|Rep: Clathrin heavy chain - Babesia bovis
Length = 1676
Score = 57.6 bits (133), Expect = 3e-07
Identities = 50/175 (28%), Positives = 75/175 (42%), Gaps = 6/175 (3%)
Frame = +3
Query: 255 LISLLEAALGLERAHMGMFTELAILYSKYKPVKMREHLELFWSR------VNIPKVLRAA 416
LI LLE + + + TELAI +KYKP ++ H + ++ +N +V R
Sbjct: 1343 LIKLLEKSA----PSVAVSTELAIAIAKYKPEELMNHFKTNFTTEELLVCINTARVAREC 1398
Query: 417 EHAHLWSELVFLYDKYEEYDNAALTMMQHPTRLGARDTSKT*SLKSRTWNCTTKLSNFT* 596
+ LW E V+LY + D A ++M+ H + + K +F
Sbjct: 1399 CNLWLWQEAVYLYS-LDTPDTALISMIAHYGLAWDEKLFFETAATANNPEALYKAIHFCI 1457
Query: 597 TTSHFLLNDLLLVLAPRMDHTRAVNFFTKAGHLQLVKAYLRSVQSLNNKAVNEAL 761
LL+ LL R+D R V AG L L + YL V + AVN+AL
Sbjct: 1458 QCKPLLLSRLLACAKGRVDAVRVVKILRNAGCLGLARNYLEQVADKTSGAVNDAL 1512
Score = 52.4 bits (120), Expect = 1e-05
Identities = 23/85 (27%), Positives = 47/85 (55%)
Frame = +1
Query: 1 AKLLYNNVSNFARLAITLVHLKEFQGAVDSARKANSTRTWKEVCFACVDAGEFRLAQMCG 180
A L+Y+++ NFA+LA+ +HL EF A D+A + + + ++V CV + A
Sbjct: 1258 AVLIYSSIPNFAKLALCHLHLGEFYQAADAALNSRNPQVLRQVVEECVGKNQLGTAHKVA 1317
Query: 181 LHIVVHADELEDLINYYQDRGHFDD 255
+ ++ + D L ++ Y+ G+ ++
Sbjct: 1318 IELLTYPDFLPGIVTLYETTGNTNE 1342
>UniRef50_Q4T6Z2 Cluster: Chromosome undetermined SCAF8478, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF8478,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 144
Score = 52.8 bits (121), Expect = 9e-06
Identities = 34/78 (43%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
Frame = +2
Query: 8 SCITTSATSPVL---LLLWCI*KNFKVPWTARVRPTLRAHGRRSASRAWTPVNSDSRKCA 178
SC TT TSP L LW + ++ W RPT G++ A R W NSD KCA
Sbjct: 69 SCYTT--TSPPLGAWRRLWSTSGSTRLLWMVPARPTAPGPGKKCALRVWMGRNSDWPKCA 126
Query: 179 DCTL*YMLTNLKTSSITT 232
CTL ML N K S TT
Sbjct: 127 VCTLWSMLMNWKNSLTTT 144
>UniRef50_Q4TE15 Cluster: Chromosome 7 SCAF5879, whole genome
shotgun sequence; n=4; Tetraodon nigroviridis|Rep:
Chromosome 7 SCAF5879, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 330
Score = 41.9 bits (94), Expect = 0.018
Identities = 16/21 (76%), Positives = 21/21 (100%)
Frame = +2
Query: 548 KVANMELYYKAIQFYLDYKPL 610
+VAN+ELYYKA+QFYL++KPL
Sbjct: 1 QVANVELYYKAVQFYLEFKPL 21
Score = 41.5 bits (93), Expect = 0.023
Identities = 18/24 (75%), Positives = 21/24 (87%)
Frame = +3
Query: 612 LLNDLLLVLAPRMDHTRAVNFFTK 683
LLNDLL+VL+PR DH+RAV FF K
Sbjct: 22 LLNDLLMVLSPRRDHSRAVTFFGK 45
Score = 35.9 bits (79), Expect = 1.2
Identities = 19/42 (45%), Positives = 24/42 (57%)
Frame = +3
Query: 651 DHTRAVNFFTKAGHLQLVKAYLRSVQSLNNKAVNEALTRCLL 776
D + F + L LVK LRSVQ+ NNK+VNEAL +
Sbjct: 66 DSQGVLKFPLQVKQLPLVKPLLRSVQNHNNKSVNEALNNLFI 107
>UniRef50_Q54TN3 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 321
Score = 38.7 bits (86), Expect = 0.16
Identities = 18/52 (34%), Positives = 27/52 (51%)
Frame = +1
Query: 82 VDSARKANSTRTWKEVCFACVDAGEFRLAQMCGLHIVVHADELEDLINYYQD 237
VD +K N + + +C+ C GE + + L I D+ +LINYYQD
Sbjct: 90 VDKIKKKNLEKKVRMMCYDCRGHGETKTSDDSNLSIETMVDDCANLINYYQD 141
>UniRef50_A7B3Y3 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus gnavus ATCC 29149|Rep: Putative
uncharacterized protein - Ruminococcus gnavus ATCC 29149
Length = 919
Score = 38.3 bits (85), Expect = 0.22
Identities = 17/55 (30%), Positives = 28/55 (50%)
Frame = +3
Query: 351 KMREHLELFWSRVNIPKVLRAAEHAHLWSELVFLYDKYEEYDNAALTMMQHPTRL 515
++++ L W R I K L HAH + + +Y+ EEY + M+ HPT +
Sbjct: 575 RLKKQPTLLWLREEIGKELEQVRHAHDEAIIRPIYNSLEEYTTGSCDMLAHPTNI 629
>UniRef50_A0TJ86 Cluster: Putative uncharacterized protein; n=1;
Burkholderia ambifaria MC40-6|Rep: Putative
uncharacterized protein - Burkholderia ambifaria MC40-6
Length = 613
Score = 33.1 bits (72), Expect = 8.1
Identities = 22/52 (42%), Positives = 30/52 (57%), Gaps = 3/52 (5%)
Frame = +3
Query: 216 PHQLL-PGPRSL*RLISLL--EAALGLERAHMGMFTELAILYSKYKPVKMRE 362
PH+L PG RS RL S+L +A +RAH L +YS+ KPVK ++
Sbjct: 537 PHRLPGPGGRSRARLASVLASDARTDRQRAHSMTLPPLHRVYSRMKPVKRKK 588
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 736,706,577
Number of Sequences: 1657284
Number of extensions: 14101627
Number of successful extensions: 34652
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 33331
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 34618
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 66673674990
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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