Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= NV021849
(794 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AY515704-1|AAR99654.1| 585|Homo sapiens bestrophin 1 protein. 86 1e-16
AF073501-1|AAC33766.1| 585|Homo sapiens vitelliform macular dys... 86 1e-16
AF073500-1|AAC64926.1| 585|Homo sapiens vitelliform macular dys... 86 1e-16
AF057170-1|AAC64344.1| 435|Homo sapiens bestrophin protein. 86 1e-16
AF057169-1|AAC64343.1| 585|Homo sapiens bestrophin protein. 86 1e-16
AY515705-1|AAR99655.1| 509|Homo sapiens bestrophin 2 protein. 84 6e-16
AF440756-1|AAM76995.1| 509|Homo sapiens vitelliform macular dys... 84 6e-16
AY515706-1|AAR99656.1| 668|Homo sapiens bestrophin 3 protein. 83 8e-16
AK096459-1|BAC04797.1| 668|Homo sapiens protein ( Homo sapiens ... 83 8e-16
AF440758-1|AAM76997.1| 398|Homo sapiens vitelliform macular dys... 83 8e-16
BC101823-1|AAI01824.1| 473|Homo sapiens bestrophin 4 protein. 79 2e-14
AY515707-1|AAR99657.1| 473|Homo sapiens bestrophin 4 protein. 79 2e-14
AL592166-10|CAI13005.1| 473|Homo sapiens vitelliform macular dy... 79 2e-14
AF440757-1|AAM76996.1| 473|Homo sapiens vitelliform macular dys... 79 2e-14
AK000139-1|BAA90970.1| 466|Homo sapiens protein ( Homo sapiens ... 73 9e-13
BC041664-1|AAH41664.1| 604|Homo sapiens BEST1 protein protein. 69 2e-11
BC015220-1|AAH15220.1| 498|Homo sapiens BEST1 protein protein. 69 2e-11
AB209451-1|BAD92688.1| 376|Homo sapiens bestrophin variant prot... 50 1e-05
BC006440-1|AAH06440.1| 72|Homo sapiens BEST3 protein protein. 31 3.6
BC119643-1|AAI19644.1| 370|Homo sapiens keratin associated prot... 30 8.4
AB076354-1|BAD01541.1| 370|Homo sapiens keratin associated prot... 30 8.4
>AY515704-1|AAR99654.1| 585|Homo sapiens bestrophin 1 protein.
Length = 585
Score = 86.2 bits (204), Expect = 1e-16
Identities = 40/84 (47%), Positives = 52/84 (61%)
Frame = +2
Query: 257 VYKLVWREXXXXXXXXXXXXXXXRFALTEQQQRVFEKVRQYFGAQSESIPMSFVLGFYVS 436
+YKL++ E R ALTE+QQ +FEK+ Y + + IP+SFVLGFYV+
Sbjct: 28 IYKLLYGEFLIFLLCYYIIRFIYRLALTEEQQLMFEKLTLYCDSYIQLIPISFVLGFYVT 87
Query: 437 LVVKRWWEQYKLLPWPDTLALFIS 508
LVV RWW QY+ LPWPD L +S
Sbjct: 88 LVVTRWWNQYENLPWPDRLMSLVS 111
Score = 37.9 bits (84), Expect = 0.042
Identities = 20/44 (45%), Positives = 29/44 (65%), Gaps = 1/44 (2%)
Frame = +1
Query: 505 LSGIPGAVS-KDETGRLMRRNIVRYAILAYVITLQRVSLRVKRK 633
+S + G V KDE GRL+RR ++RYA L V+ L+ VS V ++
Sbjct: 107 MSLVSGFVEGKDEQGRLLRRTLIRYANLGNVLILRSVSTAVYKR 150
>AF073501-1|AAC33766.1| 585|Homo sapiens vitelliform macular
dystrophy protein protein.
Length = 585
Score = 86.2 bits (204), Expect = 1e-16
Identities = 40/84 (47%), Positives = 52/84 (61%)
Frame = +2
Query: 257 VYKLVWREXXXXXXXXXXXXXXXRFALTEQQQRVFEKVRQYFGAQSESIPMSFVLGFYVS 436
+YKL++ E R ALTE+QQ +FEK+ Y + + IP+SFVLGFYV+
Sbjct: 28 IYKLLYGEFLIFLLCYYIIRFIYRLALTEEQQLMFEKLTLYCDSYIQLIPISFVLGFYVT 87
Query: 437 LVVKRWWEQYKLLPWPDTLALFIS 508
LVV RWW QY+ LPWPD L +S
Sbjct: 88 LVVTRWWNQYENLPWPDRLMSLVS 111
Score = 37.9 bits (84), Expect = 0.042
Identities = 20/44 (45%), Positives = 29/44 (65%), Gaps = 1/44 (2%)
Frame = +1
Query: 505 LSGIPGAVS-KDETGRLMRRNIVRYAILAYVITLQRVSLRVKRK 633
+S + G V KDE GRL+RR ++RYA L V+ L+ VS V ++
Sbjct: 107 MSLVSGFVEGKDEQGRLLRRTLIRYANLGNVLILRSVSTAVYKR 150
>AF073500-1|AAC64926.1| 585|Homo sapiens vitelliform macular
dystrophy protein protein.
Length = 585
Score = 86.2 bits (204), Expect = 1e-16
Identities = 40/84 (47%), Positives = 52/84 (61%)
Frame = +2
Query: 257 VYKLVWREXXXXXXXXXXXXXXXRFALTEQQQRVFEKVRQYFGAQSESIPMSFVLGFYVS 436
+YKL++ E R ALTE+QQ +FEK+ Y + + IP+SFVLGFYV+
Sbjct: 28 IYKLLYGEFLIFLLCYYIIRFIYRLALTEEQQLMFEKLTLYCDSYIQLIPISFVLGFYVT 87
Query: 437 LVVKRWWEQYKLLPWPDTLALFIS 508
LVV RWW QY+ LPWPD L +S
Sbjct: 88 LVVTRWWNQYENLPWPDRLMSLVS 111
Score = 37.9 bits (84), Expect = 0.042
Identities = 20/44 (45%), Positives = 29/44 (65%), Gaps = 1/44 (2%)
Frame = +1
Query: 505 LSGIPGAVS-KDETGRLMRRNIVRYAILAYVITLQRVSLRVKRK 633
+S + G V KDE GRL+RR ++RYA L V+ L+ VS V ++
Sbjct: 107 MSLVSGFVEGKDEQGRLLRRTLIRYANLGNVLILRSVSTAVYKR 150
>AF057170-1|AAC64344.1| 435|Homo sapiens bestrophin protein.
Length = 435
Score = 86.2 bits (204), Expect = 1e-16
Identities = 40/84 (47%), Positives = 52/84 (61%)
Frame = +2
Query: 257 VYKLVWREXXXXXXXXXXXXXXXRFALTEQQQRVFEKVRQYFGAQSESIPMSFVLGFYVS 436
+YKL++ E R ALTE+QQ +FEK+ Y + + IP+SFVLGFYV+
Sbjct: 28 IYKLLYGEFLIFLLCYYIIRFIYRLALTEEQQLMFEKLTLYCDSYIQLIPISFVLGFYVT 87
Query: 437 LVVKRWWEQYKLLPWPDTLALFIS 508
LVV RWW QY+ LPWPD L +S
Sbjct: 88 LVVTRWWNQYENLPWPDRLMSLVS 111
Score = 37.9 bits (84), Expect = 0.042
Identities = 20/44 (45%), Positives = 29/44 (65%), Gaps = 1/44 (2%)
Frame = +1
Query: 505 LSGIPGAVS-KDETGRLMRRNIVRYAILAYVITLQRVSLRVKRK 633
+S + G V KDE GRL+RR ++RYA L V+ L+ VS V ++
Sbjct: 107 MSLVSGFVEGKDEQGRLLRRTLIRYANLGNVLILRSVSTAVYKR 150
>AF057169-1|AAC64343.1| 585|Homo sapiens bestrophin protein.
Length = 585
Score = 86.2 bits (204), Expect = 1e-16
Identities = 40/84 (47%), Positives = 52/84 (61%)
Frame = +2
Query: 257 VYKLVWREXXXXXXXXXXXXXXXRFALTEQQQRVFEKVRQYFGAQSESIPMSFVLGFYVS 436
+YKL++ E R ALTE+QQ +FEK+ Y + + IP+SFVLGFYV+
Sbjct: 28 IYKLLYGEFLIFLLCYYIIRFIYRLALTEEQQLMFEKLTLYCDSYIQLIPISFVLGFYVT 87
Query: 437 LVVKRWWEQYKLLPWPDTLALFIS 508
LVV RWW QY+ LPWPD L +S
Sbjct: 88 LVVTRWWNQYENLPWPDRLMSLVS 111
Score = 37.9 bits (84), Expect = 0.042
Identities = 20/44 (45%), Positives = 29/44 (65%), Gaps = 1/44 (2%)
Frame = +1
Query: 505 LSGIPGAVS-KDETGRLMRRNIVRYAILAYVITLQRVSLRVKRK 633
+S + G V KDE GRL+RR ++RYA L V+ L+ VS V ++
Sbjct: 107 MSLVSGFVEGKDEQGRLLRRTLIRYANLGNVLILRSVSTAVYKR 150
>AY515705-1|AAR99655.1| 509|Homo sapiens bestrophin 2 protein.
Length = 509
Score = 83.8 bits (198), Expect = 6e-16
Identities = 39/84 (46%), Positives = 49/84 (58%)
Frame = +2
Query: 257 VYKLVWREXXXXXXXXXXXXXXXRFALTEQQQRVFEKVRQYFGAQSESIPMSFVLGFYVS 436
+YKL+WRE RF LTE Q+R FEK+ Y + IP+SFVLGFYV+
Sbjct: 28 IYKLLWRELLCFLGFYMALSAAYRFVLTEGQKRYFEKLVIYCDQYASLIPVSFVLGFYVT 87
Query: 437 LVVKRWWEQYKLLPWPDTLALFIS 508
LVV RWW QY +P PD L ++
Sbjct: 88 LVVNRWWSQYLCMPLPDALMCVVA 111
Score = 35.5 bits (78), Expect = 0.22
Identities = 15/33 (45%), Positives = 21/33 (63%)
Frame = +3
Query: 663 SGLMLESERKVFEKMDGKSPMSKYWMPLVWATN 761
+G M ERK FE ++ S +KYW+P VW +N
Sbjct: 160 AGFMTREERKKFENLN--SSYNKYWVPCVWFSN 190
Score = 33.1 bits (72), Expect = 1.2
Identities = 17/41 (41%), Positives = 27/41 (65%), Gaps = 1/41 (2%)
Frame = +1
Query: 514 IPGAV-SKDETGRLMRRNIVRYAILAYVITLQRVSLRVKRK 633
+ G V +D+ GRL RR ++RYA L+ V+ L+ VS V ++
Sbjct: 110 VAGTVHGRDDRGRLYRRTLMRYAGLSAVLILRSVSTAVFKR 150
>AF440756-1|AAM76995.1| 509|Homo sapiens vitelliform macular
dystrophy 2-like protein 1 protein.
Length = 509
Score = 83.8 bits (198), Expect = 6e-16
Identities = 39/84 (46%), Positives = 49/84 (58%)
Frame = +2
Query: 257 VYKLVWREXXXXXXXXXXXXXXXRFALTEQQQRVFEKVRQYFGAQSESIPMSFVLGFYVS 436
+YKL+WRE RF LTE Q+R FEK+ Y + IP+SFVLGFYV+
Sbjct: 28 IYKLLWRELLCFLGFYMALSAAYRFVLTEGQKRYFEKLVIYCDQYASLIPVSFVLGFYVT 87
Query: 437 LVVKRWWEQYKLLPWPDTLALFIS 508
LVV RWW QY +P PD L ++
Sbjct: 88 LVVNRWWSQYLCMPLPDALMCVVA 111
Score = 35.5 bits (78), Expect = 0.22
Identities = 15/33 (45%), Positives = 21/33 (63%)
Frame = +3
Query: 663 SGLMLESERKVFEKMDGKSPMSKYWMPLVWATN 761
+G M ERK FE ++ S +KYW+P VW +N
Sbjct: 160 AGFMTREERKKFENLN--SSYNKYWVPCVWFSN 190
Score = 33.1 bits (72), Expect = 1.2
Identities = 17/41 (41%), Positives = 27/41 (65%), Gaps = 1/41 (2%)
Frame = +1
Query: 514 IPGAV-SKDETGRLMRRNIVRYAILAYVITLQRVSLRVKRK 633
+ G V +D+ GRL RR ++RYA L+ V+ L+ VS V ++
Sbjct: 110 VAGTVHGRDDRGRLYRRTLMRYAGLSAVLILRSVSTAVFKR 150
>AY515706-1|AAR99656.1| 668|Homo sapiens bestrophin 3 protein.
Length = 668
Score = 83.4 bits (197), Expect = 8e-16
Identities = 40/92 (43%), Positives = 52/92 (56%)
Frame = +2
Query: 239 LQMERRVYKLVWREXXXXXXXXXXXXXXXRFALTEQQQRVFEKVRQYFGAQSESIPMSFV 418
L+ +YKL++RE R LT Q+R FEK+ Y +E IP++FV
Sbjct: 22 LKWRGSIYKLLYREFIVFAVLYTAISLVYRLLLTGVQKRYFEKLSIYCDRYAEQIPVTFV 81
Query: 419 LGFYVSLVVKRWWEQYKLLPWPDTLALFISQA 514
LGFYV+LVV RWW Q+ LPWPD L IS +
Sbjct: 82 LGFYVTLVVNRWWNQFVNLPWPDRLMFLISSS 113
Score = 35.9 bits (79), Expect = 0.17
Identities = 15/33 (45%), Positives = 20/33 (60%)
Frame = +3
Query: 663 SGLMLESERKVFEKMDGKSPMSKYWMPLVWATN 761
+G M ERK+F + KSP KYW+P +W N
Sbjct: 160 AGFMTTDERKLFNHL--KSPHLKYWVPFIWFGN 190
Score = 33.9 bits (74), Expect = 0.68
Identities = 14/28 (50%), Positives = 21/28 (75%)
Frame = +3
Query: 174 MTISYAGEVPNGSSFGCFWRILCKWRGA 257
MT++Y+ +V N + FG F R+L KWRG+
Sbjct: 1 MTVTYSSKVANATFFG-FHRLLLKWRGS 27
Score = 31.5 bits (68), Expect = 3.6
Identities = 14/37 (37%), Positives = 22/37 (59%)
Frame = +1
Query: 535 DETGRLMRRNIVRYAILAYVITLQRVSLRVKRKISNM 645
DE GRL+RR ++RY L ++ + VS V ++ M
Sbjct: 118 DEHGRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTM 154
>AK096459-1|BAC04797.1| 668|Homo sapiens protein ( Homo sapiens
cDNA FLJ39140 fis, clone NTONG2009233, moderately
similar to BESTROPHIN. ).
Length = 668
Score = 83.4 bits (197), Expect = 8e-16
Identities = 40/92 (43%), Positives = 52/92 (56%)
Frame = +2
Query: 239 LQMERRVYKLVWREXXXXXXXXXXXXXXXRFALTEQQQRVFEKVRQYFGAQSESIPMSFV 418
L+ +YKL++RE R LT Q+R FEK+ Y +E IP++FV
Sbjct: 22 LKWRGSIYKLLYREFIVFAVLYTAISLVYRLLLTGVQKRYFEKLSIYCDRYAEQIPVTFV 81
Query: 419 LGFYVSLVVKRWWEQYKLLPWPDTLALFISQA 514
LGFYV+LVV RWW Q+ LPWPD L IS +
Sbjct: 82 LGFYVTLVVNRWWNQFVNLPWPDRLMFLISSS 113
Score = 35.9 bits (79), Expect = 0.17
Identities = 15/33 (45%), Positives = 20/33 (60%)
Frame = +3
Query: 663 SGLMLESERKVFEKMDGKSPMSKYWMPLVWATN 761
+G M ERK+F + KSP KYW+P +W N
Sbjct: 160 AGFMTTDERKLFNHL--KSPHLKYWVPFIWFGN 190
Score = 33.9 bits (74), Expect = 0.68
Identities = 14/28 (50%), Positives = 21/28 (75%)
Frame = +3
Query: 174 MTISYAGEVPNGSSFGCFWRILCKWRGA 257
MT++Y+ +V N + FG F R+L KWRG+
Sbjct: 1 MTVTYSSKVANATFFG-FHRLLLKWRGS 27
Score = 31.5 bits (68), Expect = 3.6
Identities = 14/37 (37%), Positives = 22/37 (59%)
Frame = +1
Query: 535 DETGRLMRRNIVRYAILAYVITLQRVSLRVKRKISNM 645
DE GRL+RR ++RY L ++ + VS V ++ M
Sbjct: 118 DEHGRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTM 154
>AF440758-1|AAM76997.1| 398|Homo sapiens vitelliform macular
dystrophy 2-like protein 3 protein.
Length = 398
Score = 83.4 bits (197), Expect = 8e-16
Identities = 40/92 (43%), Positives = 52/92 (56%)
Frame = +2
Query: 239 LQMERRVYKLVWREXXXXXXXXXXXXXXXRFALTEQQQRVFEKVRQYFGAQSESIPMSFV 418
L+ +YKL++RE R LT Q+R FEK+ Y +E IP++FV
Sbjct: 22 LKWRGSIYKLLYREFIVFAVLYTAISLVYRLLLTGVQKRYFEKLSIYCDRYAEQIPVTFV 81
Query: 419 LGFYVSLVVKRWWEQYKLLPWPDTLALFISQA 514
LGFYV+LVV RWW Q+ LPWPD L IS +
Sbjct: 82 LGFYVTLVVNRWWNQFVNLPWPDRLMFLISSS 113
Score = 35.9 bits (79), Expect = 0.17
Identities = 15/33 (45%), Positives = 20/33 (60%)
Frame = +3
Query: 663 SGLMLESERKVFEKMDGKSPMSKYWMPLVWATN 761
+G M ERK+F + KSP KYW+P +W N
Sbjct: 160 AGFMTTDERKLFNHL--KSPHLKYWVPFIWFGN 190
Score = 33.9 bits (74), Expect = 0.68
Identities = 14/28 (50%), Positives = 21/28 (75%)
Frame = +3
Query: 174 MTISYAGEVPNGSSFGCFWRILCKWRGA 257
MT++Y+ +V N + FG F R+L KWRG+
Sbjct: 1 MTVTYSSKVANATFFG-FHRLLLKWRGS 27
Score = 31.5 bits (68), Expect = 3.6
Identities = 14/37 (37%), Positives = 22/37 (59%)
Frame = +1
Query: 535 DETGRLMRRNIVRYAILAYVITLQRVSLRVKRKISNM 645
DE GRL+RR ++RY L ++ + VS V ++ M
Sbjct: 118 DEHGRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTM 154
>BC101823-1|AAI01824.1| 473|Homo sapiens bestrophin 4 protein.
Length = 473
Score = 78.6 bits (185), Expect = 2e-14
Identities = 49/153 (32%), Positives = 72/153 (47%)
Frame = +2
Query: 239 LQMERRVYKLVWREXXXXXXXXXXXXXXXRFALTEQQQRVFEKVRQYFGAQSESIPMSFV 418
L+ +YKL+++E R LT++Q+ V+ +V +Y ++ IP+SFV
Sbjct: 22 LRWRGSIYKLLYKEFLLFGALYAVLSITYRLLLTQEQRYVYAQVARYCNRSADLIPLSFV 81
Query: 419 LGFYVSLVVKRWWEQYKLLPWPDTLALFISQAYLERSVKTRRAD**EEIL*DTPSSPTSS 598
LGFYV+LVV RWW QY +P PD L IS + + R L + +
Sbjct: 82 LGFYVTLVVNRWWSQYTSIPLPDQLMCVISASVHGVDQRGRLL---RRTLIRYANLASVL 138
Query: 599 RYRGCLLG*KERFPTWQHVVDFRSYVGKREKSF 697
R +RFPT +HVVD + K F
Sbjct: 139 VLRSVSTRVLKRFPTMEHVVDAGFMSQEERKKF 171
Score = 40.3 bits (90), Expect = 0.008
Identities = 18/37 (48%), Positives = 26/37 (70%)
Frame = +1
Query: 535 DETGRLMRRNIVRYAILAYVITLQRVSLRVKRKISNM 645
D+ GRL+RR ++RYA LA V+ L+ VS RV ++ M
Sbjct: 118 DQRGRLLRRTLIRYANLASVLVLRSVSTRVLKRFPTM 154
Score = 39.5 bits (88), Expect = 0.014
Identities = 17/33 (51%), Positives = 22/33 (66%)
Frame = +3
Query: 663 SGLMLESERKVFEKMDGKSPMSKYWMPLVWATN 761
+G M + ERK FE + KS +KYW+P VW TN
Sbjct: 160 AGFMSQEERKKFESL--KSDFNKYWVPCVWFTN 190
>AY515707-1|AAR99657.1| 473|Homo sapiens bestrophin 4 protein.
Length = 473
Score = 78.6 bits (185), Expect = 2e-14
Identities = 49/153 (32%), Positives = 72/153 (47%)
Frame = +2
Query: 239 LQMERRVYKLVWREXXXXXXXXXXXXXXXRFALTEQQQRVFEKVRQYFGAQSESIPMSFV 418
L+ +YKL+++E R LT++Q+ V+ +V +Y ++ IP+SFV
Sbjct: 22 LRWRGSIYKLLYKEFLLFGALYAVLSITYRLLLTQEQRYVYAQVARYCNRSADLIPLSFV 81
Query: 419 LGFYVSLVVKRWWEQYKLLPWPDTLALFISQAYLERSVKTRRAD**EEIL*DTPSSPTSS 598
LGFYV+LVV RWW QY +P PD L IS + + R L + +
Sbjct: 82 LGFYVTLVVNRWWSQYTSIPLPDQLMCVISASVHGVDQRGRLL---RRTLIRYANLASVL 138
Query: 599 RYRGCLLG*KERFPTWQHVVDFRSYVGKREKSF 697
R +RFPT +HVVD + K F
Sbjct: 139 VLRSVSTRVLKRFPTMEHVVDAGFMSQEERKKF 171
Score = 40.3 bits (90), Expect = 0.008
Identities = 18/37 (48%), Positives = 26/37 (70%)
Frame = +1
Query: 535 DETGRLMRRNIVRYAILAYVITLQRVSLRVKRKISNM 645
D+ GRL+RR ++RYA LA V+ L+ VS RV ++ M
Sbjct: 118 DQRGRLLRRTLIRYANLASVLVLRSVSTRVLKRFPTM 154
Score = 39.5 bits (88), Expect = 0.014
Identities = 17/33 (51%), Positives = 22/33 (66%)
Frame = +3
Query: 663 SGLMLESERKVFEKMDGKSPMSKYWMPLVWATN 761
+G M + ERK FE + KS +KYW+P VW TN
Sbjct: 160 AGFMSQEERKKFESL--KSDFNKYWVPCVWFTN 190
>AL592166-10|CAI13005.1| 473|Homo sapiens vitelliform macular
dystrophy 2-like 2 protein.
Length = 473
Score = 78.6 bits (185), Expect = 2e-14
Identities = 49/153 (32%), Positives = 72/153 (47%)
Frame = +2
Query: 239 LQMERRVYKLVWREXXXXXXXXXXXXXXXRFALTEQQQRVFEKVRQYFGAQSESIPMSFV 418
L+ +YKL+++E R LT++Q+ V+ +V +Y ++ IP+SFV
Sbjct: 22 LRWRGSIYKLLYKEFLLFGALYAVLSITYRLLLTQEQRYVYAQVARYCNRSADLIPLSFV 81
Query: 419 LGFYVSLVVKRWWEQYKLLPWPDTLALFISQAYLERSVKTRRAD**EEIL*DTPSSPTSS 598
LGFYV+LVV RWW QY +P PD L IS + + R L + +
Sbjct: 82 LGFYVTLVVNRWWSQYTSIPLPDQLMCVISASVHGVDQRGRLL---RRTLIRYANLASVL 138
Query: 599 RYRGCLLG*KERFPTWQHVVDFRSYVGKREKSF 697
R +RFPT +HVVD + K F
Sbjct: 139 VLRSVSTRVLKRFPTMEHVVDAGFMSQEERKKF 171
Score = 40.3 bits (90), Expect = 0.008
Identities = 18/37 (48%), Positives = 26/37 (70%)
Frame = +1
Query: 535 DETGRLMRRNIVRYAILAYVITLQRVSLRVKRKISNM 645
D+ GRL+RR ++RYA LA V+ L+ VS RV ++ M
Sbjct: 118 DQRGRLLRRTLIRYANLASVLVLRSVSTRVLKRFPTM 154
Score = 39.5 bits (88), Expect = 0.014
Identities = 17/33 (51%), Positives = 22/33 (66%)
Frame = +3
Query: 663 SGLMLESERKVFEKMDGKSPMSKYWMPLVWATN 761
+G M + ERK FE + KS +KYW+P VW TN
Sbjct: 160 AGFMSQEERKKFESL--KSDFNKYWVPCVWFTN 190
>AF440757-1|AAM76996.1| 473|Homo sapiens vitelliform macular
dystrophy 2-like protein 2 protein.
Length = 473
Score = 78.6 bits (185), Expect = 2e-14
Identities = 49/153 (32%), Positives = 72/153 (47%)
Frame = +2
Query: 239 LQMERRVYKLVWREXXXXXXXXXXXXXXXRFALTEQQQRVFEKVRQYFGAQSESIPMSFV 418
L+ +YKL+++E R LT++Q+ V+ +V +Y ++ IP+SFV
Sbjct: 22 LRWRGSIYKLLYKEFLLFGALYAVLSITYRLLLTQEQRYVYAQVARYCNRSADLIPLSFV 81
Query: 419 LGFYVSLVVKRWWEQYKLLPWPDTLALFISQAYLERSVKTRRAD**EEIL*DTPSSPTSS 598
LGFYV+LVV RWW QY +P PD L IS + + R L + +
Sbjct: 82 LGFYVTLVVNRWWSQYTSIPLPDQLMCVISASVHGVDQRGRLL---RRTLIRYANLASVL 138
Query: 599 RYRGCLLG*KERFPTWQHVVDFRSYVGKREKSF 697
R +RFPT +HVVD + K F
Sbjct: 139 VLRSVSTRVLKRFPTMEHVVDAGFMSQEERKKF 171
Score = 40.3 bits (90), Expect = 0.008
Identities = 18/37 (48%), Positives = 26/37 (70%)
Frame = +1
Query: 535 DETGRLMRRNIVRYAILAYVITLQRVSLRVKRKISNM 645
D+ GRL+RR ++RYA LA V+ L+ VS RV ++ M
Sbjct: 118 DQRGRLLRRTLIRYANLASVLVLRSVSTRVLKRFPTM 154
Score = 39.5 bits (88), Expect = 0.014
Identities = 17/33 (51%), Positives = 22/33 (66%)
Frame = +3
Query: 663 SGLMLESERKVFEKMDGKSPMSKYWMPLVWATN 761
+G M + ERK FE + KS +KYW+P VW TN
Sbjct: 160 AGFMSQEERKKFESL--KSDFNKYWVPCVWFTN 190
>AK000139-1|BAA90970.1| 466|Homo sapiens protein ( Homo sapiens
cDNA FLJ20132 fis, clone COL06441. ).
Length = 466
Score = 73.3 bits (172), Expect = 9e-13
Identities = 33/61 (54%), Positives = 41/61 (67%)
Frame = +2
Query: 326 RFALTEQQQRVFEKVRQYFGAQSESIPMSFVLGFYVSLVVKRWWEQYKLLPWPDTLALFI 505
RF LTE Q+R FEK+ Y + IP+SFVLGFYV+LVV RWW QY +P PD L +
Sbjct: 8 RFVLTEGQKRYFEKLVIYCDQYASLIPVSFVLGFYVTLVVNRWWSQYLCMPLPDALMCVV 67
Query: 506 S 508
+
Sbjct: 68 A 68
Score = 35.5 bits (78), Expect = 0.22
Identities = 15/33 (45%), Positives = 21/33 (63%)
Frame = +3
Query: 663 SGLMLESERKVFEKMDGKSPMSKYWMPLVWATN 761
+G M ERK FE ++ S +KYW+P VW +N
Sbjct: 117 AGFMTREERKKFENLN--SSYNKYWVPCVWFSN 147
Score = 33.1 bits (72), Expect = 1.2
Identities = 17/41 (41%), Positives = 27/41 (65%), Gaps = 1/41 (2%)
Frame = +1
Query: 514 IPGAV-SKDETGRLMRRNIVRYAILAYVITLQRVSLRVKRK 633
+ G V +D+ GRL RR ++RYA L+ V+ L+ VS V ++
Sbjct: 67 VAGTVHGRDDRGRLYRRTLMRYAGLSAVLILRSVSTAVFKR 107
>BC041664-1|AAH41664.1| 604|Homo sapiens BEST1 protein protein.
Length = 604
Score = 68.9 bits (161), Expect = 2e-11
Identities = 29/51 (56%), Positives = 37/51 (72%)
Frame = +2
Query: 356 VFEKVRQYFGAQSESIPMSFVLGFYVSLVVKRWWEQYKLLPWPDTLALFIS 508
+FEK+ Y + + IP+SFVLGFYV+LVV RWW QY+ LPWPD L +S
Sbjct: 1 MFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVS 51
Score = 37.9 bits (84), Expect = 0.042
Identities = 20/44 (45%), Positives = 29/44 (65%), Gaps = 1/44 (2%)
Frame = +1
Query: 505 LSGIPGAVS-KDETGRLMRRNIVRYAILAYVITLQRVSLRVKRK 633
+S + G V KDE GRL+RR ++RYA L V+ L+ VS V ++
Sbjct: 47 MSLVSGFVEGKDEQGRLLRRTLIRYANLGNVLILRSVSTAVYKR 90
>BC015220-1|AAH15220.1| 498|Homo sapiens BEST1 protein protein.
Length = 498
Score = 68.9 bits (161), Expect = 2e-11
Identities = 29/51 (56%), Positives = 37/51 (72%)
Frame = +2
Query: 356 VFEKVRQYFGAQSESIPMSFVLGFYVSLVVKRWWEQYKLLPWPDTLALFIS 508
+FEK+ Y + + IP+SFVLGFYV+LVV RWW QY+ LPWPD L +S
Sbjct: 1 MFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVS 51
Score = 37.9 bits (84), Expect = 0.042
Identities = 20/44 (45%), Positives = 29/44 (65%), Gaps = 1/44 (2%)
Frame = +1
Query: 505 LSGIPGAVS-KDETGRLMRRNIVRYAILAYVITLQRVSLRVKRK 633
+S + G V KDE GRL+RR ++RYA L V+ L+ VS V ++
Sbjct: 47 MSLVSGFVEGKDEQGRLLRRTLIRYANLGNVLILRSVSTAVYKR 90
>AB209451-1|BAD92688.1| 376|Homo sapiens bestrophin variant
protein.
Length = 376
Score = 50.0 bits (114), Expect = 1e-05
Identities = 19/29 (65%), Positives = 22/29 (75%)
Frame = +2
Query: 422 GFYVSLVVKRWWEQYKLLPWPDTLALFIS 508
GFYV+LVV RWW QY+ LPWPD L +S
Sbjct: 102 GFYVTLVVTRWWNQYENLPWPDRLMSLVS 130
Score = 37.9 bits (84), Expect = 0.042
Identities = 20/44 (45%), Positives = 29/44 (65%), Gaps = 1/44 (2%)
Frame = +1
Query: 505 LSGIPGAVS-KDETGRLMRRNIVRYAILAYVITLQRVSLRVKRK 633
+S + G V KDE GRL+RR ++RYA L V+ L+ VS V ++
Sbjct: 126 MSLVSGFVEGKDEQGRLLRRTLIRYANLGNVLILRSVSTAVYKR 169
>BC006440-1|AAH06440.1| 72|Homo sapiens BEST3 protein protein.
Length = 72
Score = 31.5 bits (68), Expect = 3.6
Identities = 14/37 (37%), Positives = 22/37 (59%)
Frame = +1
Query: 535 DETGRLMRRNIVRYAILAYVITLQRVSLRVKRKISNM 645
DE GRL+RR ++RY L ++ + VS V ++ M
Sbjct: 12 DEHGRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTM 48
>BC119643-1|AAI19644.1| 370|Homo sapiens keratin associated protein
10-7 protein.
Length = 370
Score = 30.3 bits (65), Expect = 8.4
Identities = 14/35 (40%), Positives = 18/35 (51%)
Frame = -3
Query: 438 RLT*KPSTNDIGIDSLCAPKYCRTFSNTLCCCSVS 334
R+T +PS G S C P C+ S L CC+ S
Sbjct: 69 RVTCEPSPCQSGCTSSCTPSCCQQSSCQLACCASS 103
>AB076354-1|BAD01541.1| 370|Homo sapiens keratin associated protein
protein.
Length = 370
Score = 30.3 bits (65), Expect = 8.4
Identities = 14/35 (40%), Positives = 18/35 (51%)
Frame = -3
Query: 438 RLT*KPSTNDIGIDSLCAPKYCRTFSNTLCCCSVS 334
R+T +PS G S C P C+ S L CC+ S
Sbjct: 69 RVTCEPSPCQSGCTSSCTPSCCQQSSCQLACCASS 103
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 113,295,317
Number of Sequences: 237096
Number of extensions: 2363801
Number of successful extensions: 5047
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 4790
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5047
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9757565650
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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