Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= NV021818
(779 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI00015B4325 Cluster: PREDICTED: similar to aconitase,... 167 3e-40
UniRef50_Q99798 Cluster: Aconitate hydratase, mitochondrial prec... 165 1e-39
UniRef50_Q9VIE8 Cluster: CG9244-PB; n=37; cellular organisms|Rep... 156 5e-37
UniRef50_Q0CSK9 Cluster: Aconitate hydratase, mitochondrial; n=2... 149 1e-34
UniRef50_P19414 Cluster: Aconitate hydratase, mitochondrial prec... 144 3e-33
UniRef50_O13966 Cluster: Aconitate hydratase, mitochondrial prec... 140 4e-32
UniRef50_Q2UTF0 Cluster: Aconitase/homoaconitase; n=9; cellular ... 122 1e-26
UniRef50_Q4PB22 Cluster: Putative uncharacterized protein; n=5; ... 117 3e-25
UniRef50_Q0USA6 Cluster: Putative uncharacterized protein; n=2; ... 116 7e-25
UniRef50_O75944 Cluster: Aconitase; n=34; cellular organisms|Rep... 112 1e-23
UniRef50_A0RTP9 Cluster: 3-isopropylmalate isomerase/aconitase A... 107 3e-22
UniRef50_Q4AHJ7 Cluster: Aconitate hydratase; n=1; Chlorobium ph... 95 2e-18
UniRef50_Q5AVN8 Cluster: Putative uncharacterized protein; n=1; ... 75 2e-12
UniRef50_O67656 Cluster: Aconitase; n=17; cellular organisms|Rep... 73 8e-12
UniRef50_Q74AD1 Cluster: Aconitate hydratase, putative; n=12; Ba... 71 2e-11
UniRef50_Q7NDZ5 Cluster: Aconitate hydratase; n=28; Bacteria|Rep... 69 1e-10
UniRef50_Q0PQM4 Cluster: Aconitase A; n=1; Endoriftia persephone... 64 4e-09
UniRef50_Q5V0F1 Cluster: Aconitate hydratase; n=8; cellular orga... 62 1e-08
UniRef50_Q5K9V9 Cluster: Homoaconitase, mitochondrial precursor;... 54 4e-06
UniRef50_Q59PT1 Cluster: Putative uncharacterized protein; n=1; ... 52 2e-05
UniRef50_Q97Z42 Cluster: Aconitate hydratase; n=3; cellular orga... 50 5e-05
UniRef50_Q0W1Q4 Cluster: 3-isopropylmalate dehydratase, large su... 49 1e-04
UniRef50_A2SQ03 Cluster: 3-isopropylmalate dehydratase; n=5; Met... 49 2e-04
UniRef50_A0HK99 Cluster: Aconitate hydratase-like; n=3; Burkhold... 48 3e-04
UniRef50_Q125M5 Cluster: Aconitate hydratase-like; n=8; Proteoba... 48 3e-04
UniRef50_Q4WUL6 Cluster: Homoaconitase, mitochondrial precursor;... 48 3e-04
UniRef50_Q5PXM8 Cluster: Aconitase A; n=3; Gammaproteobacteria|R... 47 5e-04
UniRef50_Q4J9H0 Cluster: Aconitate hydratase; n=7; cellular orga... 47 5e-04
UniRef50_P75764 Cluster: Uncharacterized protein ybhJ; n=32; Bac... 47 5e-04
UniRef50_A5ZNE1 Cluster: Putative uncharacterized protein; n=1; ... 47 6e-04
UniRef50_A7DAM6 Cluster: Aconitate hydratase domain protein; n=1... 46 8e-04
UniRef50_Q97VY2 Cluster: 3-isopropylmalate dehydratase large sub... 46 8e-04
UniRef50_Q9WYC7 Cluster: 3-isopropylmalate dehydratase large sub... 46 8e-04
UniRef50_Q58409 Cluster: 3-isopropylmalate dehydratase large sub... 46 8e-04
UniRef50_Q9I3F5 Cluster: Aconitate hydratase 1; n=98; Bacteria|R... 46 8e-04
UniRef50_O53237 Cluster: 3-isopropylmalate dehydratase large sub... 46 0.001
UniRef50_A6G875 Cluster: 3-isopropylmalate dehydratase; n=1; Ple... 46 0.001
UniRef50_O08451 Cluster: Aconitate hydratase; n=21; Bacteria|Rep... 46 0.001
UniRef50_Q4T087 Cluster: Chromosome undetermined SCAF11289, whol... 45 0.002
UniRef50_A6DRT0 Cluster: 3-isopropylmalate dehydratase; n=4; Bac... 45 0.002
UniRef50_Q5V7D3 Cluster: Aconitate hydratase I; n=4; cellular or... 45 0.002
UniRef50_Q9RNH9 Cluster: Aconitase; n=3; Bacteria|Rep: Aconitase... 45 0.002
UniRef50_Q59938 Cluster: Aconitate hydratase; n=356; cellular or... 45 0.002
UniRef50_A5WEQ7 Cluster: 2-methylisocitrate dehydratase, Fe/S-de... 44 0.003
UniRef50_P81291 Cluster: 3-isopropylmalate dehydratase large sub... 44 0.003
UniRef50_P21399 Cluster: Iron-responsive element-binding protein... 44 0.003
UniRef50_Q7WB80 Cluster: Aconitate hydratase; n=3; Bordetella|Re... 44 0.004
UniRef50_Q6A800 Cluster: 3-isopropylmalate dehydratase large sub... 44 0.004
UniRef50_Q42560 Cluster: Aconitate hydratase 1; n=35; cellular o... 44 0.004
UniRef50_A5ZND9 Cluster: Putative uncharacterized protein; n=1; ... 44 0.006
UniRef50_Q8TVF2 Cluster: 3-isopropylmalate dehydratase large sub... 44 0.006
UniRef50_Q5A379 Cluster: Putative uncharacterized protein; n=1; ... 43 0.007
UniRef50_UPI00015BAFD3 Cluster: 3-isopropylmalate dehydratase; n... 43 0.010
UniRef50_UPI0000E49144 Cluster: PREDICTED: similar to Aconitase ... 43 0.010
UniRef50_Q5FUG3 Cluster: 3-isopropylmalate dehydratase large sub... 43 0.010
UniRef50_Q1IMD4 Cluster: Aconitate hydratase-like; n=1; Acidobac... 42 0.013
UniRef50_A7CSQ0 Cluster: Aconitate hydratase 1; n=1; Opitutaceae... 42 0.013
UniRef50_A6FCI8 Cluster: Isopropylmalate isomerase large subunit... 42 0.013
UniRef50_A5C294 Cluster: Putative uncharacterized protein; n=1; ... 42 0.013
UniRef50_Q2GN26 Cluster: Homoaconitase, mitochondrial precursor;... 42 0.013
UniRef50_Q5P0Q2 Cluster: Aconitase; n=4; Proteobacteria|Rep: Aco... 42 0.017
UniRef50_A4FHT3 Cluster: Aconitate hydratase 1; n=2; Actinomycet... 42 0.017
UniRef50_Q0ZQ48 Cluster: FrbA; n=6; cellular organisms|Rep: FrbA... 42 0.023
UniRef50_Q0ADB7 Cluster: Aconitate hydratase 1; n=5; Bacteria|Re... 42 0.023
UniRef50_P49367 Cluster: Homoaconitase, mitochondrial precursor;... 42 0.023
UniRef50_Q65VS0 Cluster: 3-isopropylmalate dehydratase large sub... 42 0.023
UniRef50_Q8NQ98 Cluster: Aconitate hydratase; n=10; Bacteria|Rep... 42 0.023
UniRef50_A4M821 Cluster: Homoaconitate hydratase family protein;... 41 0.030
UniRef50_Q8TW29 Cluster: 3-isopropylmalate dehydratase large sub... 41 0.040
UniRef50_Q89X98 Cluster: 3-isopropylmalate dehydratase large sub... 41 0.040
UniRef50_A5WGT5 Cluster: 3-isopropylmalate dehydratase, large su... 40 0.053
UniRef50_A7NXJ3 Cluster: Chromosome chr5 scaffold_2, whole genom... 40 0.053
UniRef50_Q2GXH4 Cluster: Putative uncharacterized protein; n=1; ... 40 0.053
UniRef50_Q6NH63 Cluster: Aconitate hydratase; n=32; cellular org... 40 0.053
UniRef50_Q9RTY9 Cluster: 3-isopropylmalate dehydratase large sub... 40 0.070
UniRef50_A3BB05 Cluster: Putative uncharacterized protein; n=1; ... 40 0.092
UniRef50_Q82WI9 Cluster: 3-isopropylmalate dehydratase large sub... 40 0.092
UniRef50_Q1AVC5 Cluster: Homoaconitate hydratase family protein;... 39 0.12
UniRef50_A4VXS4 Cluster: 3-isopropylmalate dehydratase large sub... 39 0.12
UniRef50_Q9RTI6 Cluster: 3-isopropylmalate dehydratase large sub... 39 0.12
UniRef50_Q18GT3 Cluster: 3-isopropylmalate dehydratase large sub... 39 0.16
UniRef50_P07264 Cluster: 3-isopropylmalate dehydratase; n=473; c... 39 0.16
UniRef50_Q0C395 Cluster: Putative 3-isopropylmalate dehydratase,... 38 0.21
UniRef50_Q8KER8 Cluster: 3-isopropylmalate dehydratase, large su... 38 0.28
UniRef50_A7DIC6 Cluster: Metallophosphoesterase; n=2; Methylobac... 38 0.28
UniRef50_A0ZF76 Cluster: 3-isopropylmalate dehydratase, LeuC sub... 38 0.28
UniRef50_Q08N42 Cluster: Aconitate hydratase; n=2; Cystobacterin... 38 0.37
UniRef50_A6XPX3 Cluster: Putative uncharacterized protein; n=1; ... 38 0.37
UniRef50_A3LRP7 Cluster: 3-isopropylmalate dehydratase; n=1; Pic... 38 0.37
UniRef50_Q7N5S3 Cluster: Similar to large subunit of 3-isopropyl... 37 0.49
UniRef50_A6NVP4 Cluster: Putative uncharacterized protein; n=1; ... 37 0.49
UniRef50_P48200 Cluster: Iron-responsive element-binding protein... 37 0.49
UniRef50_Q1LAU9 Cluster: Homoaconitate hydratase family protein;... 37 0.65
UniRef50_O67078 Cluster: 3-isopropylmalate dehydratase large sub... 36 0.86
UniRef50_UPI00006D922D Cluster: COG0065: 3-isopropylmalate dehyd... 36 1.1
UniRef50_Q4WBR0 Cluster: Aconitase family protein; n=7; Pezizomy... 36 1.1
UniRef50_Q8PUG1 Cluster: 3-isopropylmalate dehydratase large sub... 36 1.5
UniRef50_Q7WPW8 Cluster: Aconitase family protein; n=2; Bordetel... 35 2.0
UniRef50_Q0VKG5 Cluster: Aconitate hydratase; n=2; Bacteria|Rep:... 35 2.0
UniRef50_Q05FR0 Cluster: 3-isopropylmalate dehydratase large sub... 35 2.0
UniRef50_A1W553 Cluster: Aconitate hydratase 1 precursor; n=8; P... 35 2.0
UniRef50_Q6BX71 Cluster: 5-aminolevulinate synthase, mitochondri... 35 2.0
UniRef50_Q938C9 Cluster: 3-isopropylmalate dehydratase large sub... 35 2.6
UniRef50_Q8KSY7 Cluster: Putative cyclase GrhE; n=1; Streptomyce... 34 3.5
UniRef50_Q6L0K5 Cluster: 3-isopropylmalate dehydratase large sub... 34 4.6
UniRef50_A0GFK5 Cluster: RAD55; n=2; Burkholderia|Rep: RAD55 - B... 33 6.1
UniRef50_Q4VDG4 Cluster: Putative 3-isopropylmalate dehydratase ... 33 6.1
UniRef50_Q8U0C0 Cluster: 3-isopropylmalate dehydratase large sub... 33 6.1
UniRef50_Q47LU6 Cluster: Putative uncharacterized protein precur... 33 8.0
UniRef50_Q30ZB6 Cluster: DTDP-4-dehydrorhamnose reductase; n=4; ... 33 8.0
>UniRef50_UPI00015B4325 Cluster: PREDICTED: similar to aconitase,
mitochondrial; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aconitase, mitochondrial - Nasonia
vitripennis
Length = 917
Score = 167 bits (406), Expect = 3e-40
Identities = 77/84 (91%), Positives = 81/84 (96%)
Frame = +3
Query: 3 LRLRPDRVAMQDATAQMAMLQFISSGLPRVAVPSTIHCDHLIEAQVGGEKDLARAKDLNK 182
LRLRPDRVAMQDATAQMAMLQFISSGLPRVAVPSTIHCDHLIEAQ+GG+KDL RAKD+NK
Sbjct: 223 LRLRPDRVAMQDATAQMAMLQFISSGLPRVAVPSTIHCDHLIEAQLGGDKDLKRAKDINK 282
Query: 183 EVYKFLETAGAKYGVGFWKPGSGI 254
EVY FL+TAGAKYGVGFW PGSGI
Sbjct: 283 EVYSFLKTAGAKYGVGFWNPGSGI 306
Score = 145 bits (352), Expect = 9e-34
Identities = 68/85 (80%), Positives = 71/85 (83%)
Frame = +2
Query: 257 HQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVK 436
HQIILENYAFPGLLMIGTDSHTPN ADAVDVMANIPWELKCPKVIGVK
Sbjct: 308 HQIILENYAFPGLLMIGTDSHTPNGGGLGGLCIGVGGADAVDVMANIPWELKCPKVIGVK 367
Query: 437 LTGKLTGWTSPKDVILKVAGILTVR 511
LTG+L GWTSPKD+ILKVAGILTV+
Sbjct: 368 LTGELKGWTSPKDIILKVAGILTVK 392
Score = 102 bits (245), Expect = 9e-21
Identities = 51/73 (69%), Positives = 57/73 (78%)
Frame = +1
Query: 508 EGGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLKFEPDAHDIA 687
+GGTGAIVEY GPGVD ISCTGMATICNMGAEIGATTSVFPYN RM+ YLK A IA
Sbjct: 392 KGGTGAIVEYFGPGVDSISCTGMATICNMGAEIGATTSVFPYNDRMKDYLKATQRA-SIA 450
Query: 688 ATANFLQATCSTA 726
+ A+ + + TA
Sbjct: 451 SAADQFKGSLLTA 463
>UniRef50_Q99798 Cluster: Aconitate hydratase, mitochondrial
precursor; n=28; cellular organisms|Rep: Aconitate
hydratase, mitochondrial precursor - Homo sapiens
(Human)
Length = 780
Score = 165 bits (400), Expect = 1e-39
Identities = 77/84 (91%), Positives = 80/84 (95%)
Frame = +3
Query: 3 LRLRPDRVAMQDATAQMAMLQFISSGLPRVAVPSTIHCDHLIEAQVGGEKDLARAKDLNK 182
LRLRPDRVAMQDATAQMAMLQFISSGL +VAVPSTIHCDHLIEAQVGGEKDL RAKD+N+
Sbjct: 89 LRLRPDRVAMQDATAQMAMLQFISSGLSKVAVPSTIHCDHLIEAQVGGEKDLRRAKDINQ 148
Query: 183 EVYKFLETAGAKYGVGFWKPGSGI 254
EVY FL TAGAKYGVGFWKPGSGI
Sbjct: 149 EVYNFLATAGAKYGVGFWKPGSGI 172
Score = 138 bits (335), Expect = 1e-31
Identities = 64/85 (75%), Positives = 70/85 (82%)
Frame = +2
Query: 257 HQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVK 436
HQIILENYA+PG+L+IGTDSHTPN ADAVDVMA IPWELKCPKVIGVK
Sbjct: 174 HQIILENYAYPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPKVIGVK 233
Query: 437 LTGKLTGWTSPKDVILKVAGILTVR 511
LTG L+GW+SPKDVILKVAGILTV+
Sbjct: 234 LTGSLSGWSSPKDVILKVAGILTVK 258
Score = 103 bits (246), Expect = 7e-21
Identities = 49/64 (76%), Positives = 53/64 (82%)
Frame = +1
Query: 508 EGGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLKFEPDAHDIA 687
+GGTGAIVEYHGPGVD ISCTGMATICNMGAEIGATTSVFPYN RM+ YL + DIA
Sbjct: 258 KGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYNHRMKKYLS-KTGREDIA 316
Query: 688 ATAN 699
A+
Sbjct: 317 NLAD 320
>UniRef50_Q9VIE8 Cluster: CG9244-PB; n=37; cellular organisms|Rep:
CG9244-PB - Drosophila melanogaster (Fruit fly)
Length = 787
Score = 156 bits (379), Expect = 5e-37
Identities = 72/84 (85%), Positives = 78/84 (92%)
Frame = +3
Query: 3 LRLRPDRVAMQDATAQMAMLQFISSGLPRVAVPSTIHCDHLIEAQVGGEKDLARAKDLNK 182
LRLRPDRVAMQDATAQMA+LQFISSGL +VAVPST+HCDHLIEAQ+GG KDLARAKDLNK
Sbjct: 96 LRLRPDRVAMQDATAQMALLQFISSGLKKVAVPSTVHCDHLIEAQIGGPKDLARAKDLNK 155
Query: 183 EVYKFLETAGAKYGVGFWKPGSGI 254
EVY FL + AKYG+GFWKPGSGI
Sbjct: 156 EVYDFLASTCAKYGLGFWKPGSGI 179
Score = 140 bits (340), Expect = 3e-32
Identities = 66/85 (77%), Positives = 70/85 (82%)
Frame = +2
Query: 257 HQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVK 436
HQIILENYAFPGLLMIGTDSHTPN ADAVDVMA+IPWELKCPKVIGV
Sbjct: 181 HQIILENYAFPGLLMIGTDSHTPNGGGLGGLCIGVGGADAVDVMADIPWELKCPKVIGVN 240
Query: 437 LTGKLTGWTSPKDVILKVAGILTVR 511
LTGK++GWTSPKDVILKVA ILTV+
Sbjct: 241 LTGKISGWTSPKDVILKVADILTVK 265
Score = 97.9 bits (233), Expect = 2e-19
Identities = 49/73 (67%), Positives = 55/73 (75%)
Frame = +1
Query: 508 EGGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLKFEPDAHDIA 687
+GGTGAI+EYHG GVD ISCTGMATICNMGAEIGATTS+FP+N RM YLK A IA
Sbjct: 265 KGGTGAIIEYHGKGVDSISCTGMATICNMGAEIGATTSLFPFNQRMADYLKSTGRA-GIA 323
Query: 688 ATANFLQATCSTA 726
+ A QA +A
Sbjct: 324 SEAQKYQAKILSA 336
>UniRef50_Q0CSK9 Cluster: Aconitate hydratase, mitochondrial; n=2;
Pezizomycotina|Rep: Aconitate hydratase, mitochondrial -
Aspergillus terreus (strain NIH 2624)
Length = 781
Score = 149 bits (360), Expect = 1e-34
Identities = 66/84 (78%), Positives = 76/84 (90%)
Frame = +3
Query: 3 LRLRPDRVAMQDATAQMAMLQFISSGLPRVAVPSTIHCDHLIEAQVGGEKDLARAKDLNK 182
L+LRPDRVA QDATAQMA+LQF+S+G+P VA P+T+HCDHLIEAQVGGEKDLARA ++NK
Sbjct: 119 LKLRPDRVACQDATAQMAILQFMSAGMPSVATPTTVHCDHLIEAQVGGEKDLARANEINK 178
Query: 183 EVYKFLETAGAKYGVGFWKPGSGI 254
EVY FL TA AKY +GFWKPGSGI
Sbjct: 179 EVYDFLATATAKYNIGFWKPGSGI 202
Score = 133 bits (321), Expect = 5e-30
Identities = 60/85 (70%), Positives = 69/85 (81%)
Frame = +2
Query: 257 HQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVK 436
HQI+LENYAFPG LMIGTDSHTPN ADAVDVMA +PWELK PKVIGVK
Sbjct: 204 HQIVLENYAFPGGLMIGTDSHTPNAGGLAMAAIGVGGADAVDVMAGLPWELKAPKVIGVK 263
Query: 437 LTGKLTGWTSPKDVILKVAGILTVR 511
LTG+++GWT+PKD+ILKVAG+LTV+
Sbjct: 264 LTGEMSGWTTPKDIILKVAGLLTVK 288
Score = 95.5 bits (227), Expect = 1e-18
Identities = 41/57 (71%), Positives = 47/57 (82%)
Frame = +1
Query: 508 EGGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLKFEPDAH 678
+GGTGAI+EYHGPGV+ +SCTGM TICNMGAEIGATTS+FP+N RM YLK H
Sbjct: 288 KGGTGAIIEYHGPGVNSLSCTGMGTICNMGAEIGATTSMFPFNDRMYDYLKATKRQH 344
>UniRef50_P19414 Cluster: Aconitate hydratase, mitochondrial
precursor; n=41; cellular organisms|Rep: Aconitate
hydratase, mitochondrial precursor - Saccharomyces
cerevisiae (Baker's yeast)
Length = 778
Score = 144 bits (348), Expect = 3e-33
Identities = 66/84 (78%), Positives = 75/84 (89%)
Frame = +3
Query: 3 LRLRPDRVAMQDATAQMAMLQFISSGLPRVAVPSTIHCDHLIEAQVGGEKDLARAKDLNK 182
L+LRPDRVA QDATAQMA+LQF+S+GLP+VA P T+HCDHLI+AQVGGEKDL RA DLNK
Sbjct: 85 LKLRPDRVACQDATAQMAILQFMSAGLPQVAKPVTVHCDHLIQAQVGGEKDLKRAIDLNK 144
Query: 183 EVYKFLETAGAKYGVGFWKPGSGI 254
EVY FL +A AKY +GFWKPGSGI
Sbjct: 145 EVYDFLASATAKYNMGFWKPGSGI 168
Score = 129 bits (312), Expect = 7e-29
Identities = 58/85 (68%), Positives = 66/85 (77%)
Frame = +2
Query: 257 HQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVK 436
HQI+LENYAFPG L+IGTDSHTPN ADAVDVMA PWELK PK++GVK
Sbjct: 170 HQIVLENYAFPGALIIGTDSHTPNAGGLGQLAIGVGGADAVDVMAGRPWELKAPKILGVK 229
Query: 437 LTGKLTGWTSPKDVILKVAGILTVR 511
LTGK+ GWTSPKD+ILK+AGI TV+
Sbjct: 230 LTGKMNGWTSPKDIILKLAGITTVK 254
Score = 81.0 bits (191), Expect = 3e-14
Identities = 37/51 (72%), Positives = 40/51 (78%)
Frame = +1
Query: 508 EGGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLK 660
+GGTG IVEY G GVD S TGM TICNMGAEIGATTSVFP+N M YL+
Sbjct: 254 KGGTGKIVEYFGDGVDTFSATGMGTICNMGAEIGATTSVFPFNKSMIEYLE 304
>UniRef50_O13966 Cluster: Aconitate hydratase, mitochondrial
precursor; n=21; cellular organisms|Rep: Aconitate
hydratase, mitochondrial precursor - Schizosaccharomyces
pombe (Fission yeast)
Length = 778
Score = 140 bits (339), Expect = 4e-32
Identities = 65/85 (76%), Positives = 70/85 (82%)
Frame = +2
Query: 257 HQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVK 436
HQI+LENYAFPG L+IGTDSHTPN ADAVDVMAN+PWELKCPKVIGVK
Sbjct: 170 HQIVLENYAFPGGLLIGTDSHTPNAGGLGMVAIGVGGADAVDVMANLPWELKCPKVIGVK 229
Query: 437 LTGKLTGWTSPKDVILKVAGILTVR 511
LTG+L GWTSPKDVILKVAGILTV+
Sbjct: 230 LTGQLKGWTSPKDVILKVAGILTVK 254
Score = 133 bits (322), Expect = 4e-30
Identities = 61/84 (72%), Positives = 70/84 (83%)
Frame = +3
Query: 3 LRLRPDRVAMQDATAQMAMLQFISSGLPRVAVPSTIHCDHLIEAQVGGEKDLARAKDLNK 182
L+LRPDRVA QDATAQMA+LQF+S+G+P VAVP T+HCDHLIEA GG DL RA NK
Sbjct: 85 LKLRPDRVACQDATAQMAILQFMSAGMPEVAVPVTVHCDHLIEAYEGGPIDLERANVTNK 144
Query: 183 EVYKFLETAGAKYGVGFWKPGSGI 254
EVY FL+TA AKY +GFW+PGSGI
Sbjct: 145 EVYDFLQTACAKYNIGFWRPGSGI 168
Score = 92.7 bits (220), Expect = 9e-18
Identities = 39/51 (76%), Positives = 45/51 (88%)
Frame = +1
Query: 508 EGGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLK 660
+GGTGAIVEY GPGV+ +SCTGM TICNMGAEIGATTS+FP+N RM YL+
Sbjct: 254 KGGTGAIVEYFGPGVESLSCTGMGTICNMGAEIGATTSIFPFNPRMSEYLR 304
>UniRef50_Q2UTF0 Cluster: Aconitase/homoaconitase; n=9; cellular
organisms|Rep: Aconitase/homoaconitase - Aspergillus
oryzae
Length = 806
Score = 122 bits (294), Expect = 1e-26
Identities = 56/84 (66%), Positives = 67/84 (79%)
Frame = +3
Query: 3 LRLRPDRVAMQDATAQMAMLQFISSGLPRVAVPSTIHCDHLIEAQVGGEKDLARAKDLNK 182
L LRPDRVA DATA MA+LQFIS+GLPRVAVP+T+H DHLI ++ G E D+ RA +
Sbjct: 98 LELRPDRVACHDATATMALLQFISAGLPRVAVPTTVHGDHLIVSEKGAEPDMKRALTEHA 157
Query: 183 EVYKFLETAGAKYGVGFWKPGSGI 254
EVY+FL +A KYG+GFWKPGSGI
Sbjct: 158 EVYEFLSSASRKYGIGFWKPGSGI 181
Score = 105 bits (251), Expect = 2e-21
Identities = 46/84 (54%), Positives = 60/84 (71%)
Frame = +2
Query: 257 HQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVK 436
H +I EN+A PG L+IGTDSHTPN +DAVD M+ +PWEL P+++GV+
Sbjct: 183 HTVIFENHAVPGGLIIGTDSHTPNAGGLAMMGIGVGGSDAVDAMSGMPWELVTPQIVGVR 242
Query: 437 LTGKLTGWTSPKDVILKVAGILTV 508
LTG+L+GW S KD+I K+AGILTV
Sbjct: 243 LTGQLSGWASTKDIICKLAGILTV 266
Score = 69.3 bits (162), Expect = 1e-10
Identities = 31/67 (46%), Positives = 40/67 (59%)
Frame = +1
Query: 511 GGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLKFEPDAHDIAA 690
GG G ++E+ GPG + + T MATICNM AEIG+T+ +FPY + M YL AH A
Sbjct: 268 GGKGRVIEFFGPGTETLGATAMATICNMSAEIGSTSCIFPYTTAMGRYLTATRRAHVAQA 327
Query: 691 TANFLQA 711
QA
Sbjct: 328 AQGVQQA 334
>UniRef50_Q4PB22 Cluster: Putative uncharacterized protein; n=5;
Fungi/Metazoa group|Rep: Putative uncharacterized
protein - Ustilago maydis (Smut fungus)
Length = 1041
Score = 117 bits (282), Expect = 3e-25
Identities = 52/84 (61%), Positives = 68/84 (80%)
Frame = +3
Query: 3 LRLRPDRVAMQDATAQMAMLQFISSGLPRVAVPSTIHCDHLIEAQVGGEKDLARAKDLNK 182
L+L+ DR+AMQDA+AQMA+LQF++ GLPR A+PS++HCDHLI+A G E DL R+ N+
Sbjct: 205 LKLKIDRLAMQDASAQMALLQFMTCGLPRTAIPSSVHCDHLIQAFEGAEADLKRSIASNQ 264
Query: 183 EVYKFLETAGAKYGVGFWKPGSGI 254
EV+ FLE+A KYG+ FW PGSGI
Sbjct: 265 EVFAFLESASKKYGIEFWGPGSGI 288
Score = 113 bits (273), Expect = 4e-24
Identities = 56/101 (55%), Positives = 64/101 (63%)
Frame = +2
Query: 257 HQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVK 436
HQI+LENYA PGLLM+GTDSHTPN ADAVD M N PWEL PKV+GV
Sbjct: 290 HQIVLENYAAPGLLMLGTDSHTPNASGLGCLAIGVGGADAVDAMTNTPWELMAPKVLGVH 349
Query: 437 LTGKLTGWTSPKDVILKVAGILTVREVPAPSWSTTDPGWTT 559
L G+L+ W +PKDVIL +AG LTVR + PG T
Sbjct: 350 LKGELSPWCTPKDVILHLAGKLTVRGGTGKIVEYSGPGLQT 390
Score = 70.5 bits (165), Expect = 4e-11
Identities = 30/50 (60%), Positives = 38/50 (76%)
Frame = +1
Query: 511 GGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLK 660
GGTG IVEY GPG+ + TG+AT+ NMGAE+GATTS FP+ M +YL+
Sbjct: 375 GGTGKIVEYSGPGLQTLPATGLATMSNMGAEVGATTSAFPFTPAMGSYLE 424
>UniRef50_Q0USA6 Cluster: Putative uncharacterized protein; n=2;
Pezizomycotina|Rep: Putative uncharacterized protein -
Phaeosphaeria nodorum (Septoria nodorum)
Length = 781
Score = 116 bits (279), Expect = 7e-25
Identities = 51/85 (60%), Positives = 63/85 (74%)
Frame = +2
Query: 257 HQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVK 436
HQ +LENY+ PGL+M+GTDSH+PN ADAVD + + PWELK PK++GVK
Sbjct: 190 HQSVLENYSAPGLMMLGTDSHSPNAGGLGAIVIGVGGADAVDALVDAPWELKAPKILGVK 249
Query: 437 LTGKLTGWTSPKDVILKVAGILTVR 511
LTG+L+GW SPKDVIL +AG LTVR
Sbjct: 250 LTGELSGWASPKDVILSLAGQLTVR 274
Score = 113 bits (273), Expect = 4e-24
Identities = 50/84 (59%), Positives = 67/84 (79%)
Frame = +3
Query: 3 LRLRPDRVAMQDATAQMAMLQFISSGLPRVAVPSTIHCDHLIEAQVGGEKDLARAKDLNK 182
L+L+PDRVAMQDA+AQMA+LQF+S GL + AVP++IHCDH+I + G + DL ++ NK
Sbjct: 105 LKLKPDRVAMQDASAQMALLQFMSCGLGKTAVPASIHCDHMIVGEKGADLDLPQSIKGNK 164
Query: 183 EVYKFLETAGAKYGVGFWKPGSGI 254
EV+ FLE+A KYG+ FW PG+GI
Sbjct: 165 EVFDFLESAAKKYGIEFWPPGAGI 188
Score = 80.2 bits (189), Expect = 5e-14
Identities = 34/50 (68%), Positives = 41/50 (82%)
Frame = +1
Query: 511 GGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLK 660
GGTG I+EY GPGV +SCTGMATICNMGAE+GATTS+FP++ YL+
Sbjct: 275 GGTGYIIEYFGPGVQTLSCTGMATICNMGAEVGATTSLFPFSPAHVPYLQ 324
>UniRef50_O75944 Cluster: Aconitase; n=34; cellular organisms|Rep:
Aconitase - Homo sapiens (Human)
Length = 600
Score = 112 bits (269), Expect = 1e-23
Identities = 53/79 (67%), Positives = 59/79 (74%)
Frame = +2
Query: 275 NYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLT 454
NYA+PG+L+IGTDSHTPN D VDVMA IP ELKC KVI +KLTG L+
Sbjct: 1 NYAYPGVLLIGTDSHTPNGGGLGGISIGVGGRDRVDVMAGIPCELKCTKVIAMKLTGSLS 60
Query: 455 GWTSPKDVILKVAGILTVR 511
GWTSPKDVILKVAGILTV+
Sbjct: 61 GWTSPKDVILKVAGILTVK 79
Score = 101 bits (243), Expect = 2e-20
Identities = 45/50 (90%), Positives = 47/50 (94%)
Frame = +1
Query: 508 EGGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYL 657
+GGTGAIVEYHGPGVD ISCTGMATICNMGAEIGATTSVFPYN RM+ YL
Sbjct: 79 KGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYNHRMKKYL 128
>UniRef50_A0RTP9 Cluster: 3-isopropylmalate isomerase/aconitase A;
n=7; cellular organisms|Rep: 3-isopropylmalate
isomerase/aconitase A - Cenarchaeum symbiosum
Length = 754
Score = 107 bits (257), Expect = 3e-22
Identities = 47/84 (55%), Positives = 63/84 (75%)
Frame = +3
Query: 3 LRLRPDRVAMQDATAQMAMLQFISSGLPRVAVPSTIHCDHLIEAQVGGEKDLARAKDLNK 182
+ L PDRVA+QD T QM MLQF+ + A+P+TIHCDHLI A+V G +D+ + D N
Sbjct: 58 VHLTPDRVALQDVTGQMVMLQFMVTRHEETALPTTIHCDHLIRAKVEGGEDMRVSLDENS 117
Query: 183 EVYKFLETAGAKYGVGFWKPGSGI 254
EV++FL++A A+YG GFWKPG+GI
Sbjct: 118 EVFRFLKSAAARYGCGFWKPGAGI 141
Score = 104 bits (250), Expect = 2e-21
Identities = 52/84 (61%), Positives = 56/84 (66%)
Frame = +2
Query: 257 HQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVK 436
HQ++LENYAFPG LMIGTDSHTPN DA + MA WEL PK IGV
Sbjct: 143 HQVVLENYAFPGGLMIGTDSHTPNAGGLGMIAVGVGGMDAAEAMAIKEWELLYPKRIGVH 202
Query: 437 LTGKLTGWTSPKDVILKVAGILTV 508
LTGK +GWTSPKDVILKV LTV
Sbjct: 203 LTGKSSGWTSPKDVILKVVEELTV 226
Score = 77.8 bits (183), Expect = 3e-13
Identities = 35/51 (68%), Positives = 40/51 (78%)
Frame = +1
Query: 511 GGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLKF 663
GGT AIVEY GPG ISCTG ATI NMGAE+GAT S+FPY++RM YL +
Sbjct: 228 GGTNAIVEYLGPGASTISCTGKATITNMGAEMGATCSIFPYDNRMGEYLGY 278
>UniRef50_Q4AHJ7 Cluster: Aconitate hydratase; n=1; Chlorobium
phaeobacteroides BS1|Rep: Aconitate hydratase -
Chlorobium phaeobacteroides BS1
Length = 141
Score = 94.7 bits (225), Expect = 2e-18
Identities = 43/63 (68%), Positives = 52/63 (82%)
Frame = +3
Query: 12 RPDRVAMQDATAQMAMLQFISSGLPRVAVPSTIHCDHLIEAQVGGEKDLARAKDLNKEVY 191
RPDRVAMQDATAQMA+LQF+ +G P+ AV S++HCDHLI+A+ G E+DLA A NKEVY
Sbjct: 73 RPDRVAMQDATAQMALLQFMQAGKPQAAVSSSVHCDHLIQAKSGAEQDLANADFTNKEVY 132
Query: 192 KFL 200
FL
Sbjct: 133 DFL 135
>UniRef50_Q5AVN8 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 326
Score = 74.9 bits (176), Expect = 2e-12
Identities = 32/51 (62%), Positives = 39/51 (76%)
Frame = +1
Query: 508 EGGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLK 660
+G TG+I+EY G G IS TGMAT+CNMGAE GATTS+FPY + M YL+
Sbjct: 135 KGSTGSIIEYFGLGAQTISATGMATVCNMGAESGATTSIFPYTASMAEYLR 185
>UniRef50_O67656 Cluster: Aconitase; n=17; cellular organisms|Rep:
Aconitase - Aquifex aeolicus
Length = 659
Score = 72.9 bits (171), Expect = 8e-12
Identities = 34/85 (40%), Positives = 48/85 (56%)
Frame = +2
Query: 257 HQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVK 436
HQ+ LE +A PG ++G+DSHTP D MA P+ LK PK++GV
Sbjct: 102 HQVHLERFAKPGKTLLGSDSHTPTAGGMGMLAIGAGGLDVAAAMAGEPFYLKMPKIVGVH 161
Query: 437 LTGKLTGWTSPKDVILKVAGILTVR 511
L GK+ W + KD+IL++ LTV+
Sbjct: 162 LKGKMPEWVTAKDIILELLRRLTVK 186
Score = 60.5 bits (140), Expect = 5e-08
Identities = 32/67 (47%), Positives = 39/67 (58%)
Frame = +1
Query: 481 LEGGRHPDCEGGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLK 660
LE R +GG G I EY G GV +S ATI NMGAE+GATTS+FP + AYL+
Sbjct: 177 LELLRRLTVKGGLGKIFEYFGEGVKELSVPERATITNMGAELGATTSIFPSDEITRAYLR 236
Query: 661 FEPDAHD 681
+ D
Sbjct: 237 AQGREED 243
Score = 38.7 bits (86), Expect = 0.16
Identities = 24/85 (28%), Positives = 42/85 (49%), Gaps = 1/85 (1%)
Frame = +3
Query: 3 LRLRPDRVAMQDATAQMAMLQFISSGLPRVAVP-STIHCDHLIEAQVGGEKDLARAKDLN 179
+ ++ D+ QDAT M L+F + G+P V S + DH ++ + N
Sbjct: 26 IAIKIDQTLTQDATGTMCYLEFEAMGVPEVKTELSVSYIDH----------NMLQTDFRN 75
Query: 180 KEVYKFLETAGAKYGVGFWKPGSGI 254
+ +K+L + K+G+ KPG+GI
Sbjct: 76 ADDHKYLMSVAKKFGIWLSKPGNGI 100
>UniRef50_Q74AD1 Cluster: Aconitate hydratase, putative; n=12;
Bacteria|Rep: Aconitate hydratase, putative - Geobacter
sulfurreducens
Length = 645
Score = 71.3 bits (167), Expect = 2e-11
Identities = 36/85 (42%), Positives = 46/85 (54%)
Frame = +2
Query: 257 HQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVK 436
HQ+ LE + PG M+G DSHT + D MA P+ L CPK+ GVK
Sbjct: 101 HQVHLERFGVPGRTMLGADSHTTSAAGLSMIAIGAGGLDVSLAMAGHPFHLPCPKIWGVK 160
Query: 437 LTGKLTGWTSPKDVILKVAGILTVR 511
LTG+L W S KDVIL++ TV+
Sbjct: 161 LTGQLQPWVSAKDVILEMLRRHTVK 185
Score = 64.1 bits (149), Expect = 4e-09
Identities = 31/60 (51%), Positives = 40/60 (66%)
Frame = +1
Query: 481 LEGGRHPDCEGGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLK 660
LE R +GG G I+EY+GPGV +S T A I NMGAE+GATTS+FP + R +L+
Sbjct: 176 LEMLRRHTVKGGVGKIIEYYGPGVATLSATDRAIIGNMGAELGATTSLFPSDHRTREFLE 235
Score = 50.4 bits (115), Expect = 5e-05
Identities = 31/86 (36%), Positives = 48/86 (55%), Gaps = 1/86 (1%)
Frame = +3
Query: 3 LRLRPDRVAMQDATAQMAMLQFISSGLPRVAVP-STIHCDHLIEAQVGGEKDLARAKDLN 179
+ L+ D +QDAT MAML+FI+ G+ RV V + + DH +L + + N
Sbjct: 25 IALKIDHALLQDATGTMAMLEFIAMGVDRVKVELAAQYIDH----------NLLQTDNRN 74
Query: 180 KEVYKFLETAGAKYGVGFWKPGSGIS 257
+ + FL TA ++GV KPG+G+S
Sbjct: 75 ADDHVFLMTAAQRFGVHLSKPGNGVS 100
>UniRef50_Q7NDZ5 Cluster: Aconitate hydratase; n=28; Bacteria|Rep:
Aconitate hydratase - Gloeobacter violaceus
Length = 645
Score = 68.9 bits (161), Expect = 1e-10
Identities = 37/98 (37%), Positives = 49/98 (50%)
Frame = +2
Query: 257 HQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVK 436
HQ+ E +A P ++G+DSHTP D MA P+ + PKV+GV+
Sbjct: 99 HQVHRERFAVPAQTLLGSDSHTPTCGGLGMLAIGAGGLDVAVAMAGEPYFIPMPKVLGVR 158
Query: 437 LTGKLTGWTSPKDVILKVAGILTVREVPAPSWSTTDPG 550
LTG L W S KDVIL++ LTV+ T PG
Sbjct: 159 LTGTLQPWCSGKDVILEMLRRLTVKGGTGRIVEYTGPG 196
Score = 61.3 bits (142), Expect = 3e-08
Identities = 32/59 (54%), Positives = 38/59 (64%)
Frame = +1
Query: 481 LEGGRHPDCEGGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYL 657
LE R +GGTG IVEY GPGV +S + TI NMGAE+GATTSVFP + +L
Sbjct: 174 LEMLRRLTVKGGTGRIVEYTGPGVASLSVSHRFTITNMGAELGATTSVFPSDEVTHRFL 232
Score = 52.4 bits (120), Expect = 1e-05
Identities = 33/83 (39%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Frame = +3
Query: 9 LRPDRVAMQDATAQMAMLQFISSGLPRVAVP-STIHCDHLIEAQVGGEKDLARAKDLNKE 185
+R D+ QDAT MA LQF + GLPRV S + DH + Q G E N +
Sbjct: 25 IRIDQTLTQDATGTMAYLQFEAMGLPRVRTKLSVSYIDHNM-LQTGFE---------NAD 74
Query: 186 VYKFLETAGAKYGVGFWKPGSGI 254
+++L++ G KYG+ F +PG+GI
Sbjct: 75 DHRYLQSVGQKYGIVFSRPGNGI 97
>UniRef50_Q0PQM4 Cluster: Aconitase A; n=1; Endoriftia persephone
'Hot96_1+Hot96_2'|Rep: Aconitase A - Endoriftia
persephone 'Hot96_1+Hot96_2'
Length = 236
Score = 64.1 bits (149), Expect = 4e-09
Identities = 29/51 (56%), Positives = 37/51 (72%)
Frame = +1
Query: 508 EGGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLK 660
+GG G I EY GPGV +S T ATI NMGAE+GATTS+FP + R + +L+
Sbjct: 16 KGGKGVIFEYAGPGVASLSLTERATITNMGAEMGATTSIFPSDERTQEFLE 66
>UniRef50_Q5V0F1 Cluster: Aconitate hydratase; n=8; cellular
organisms|Rep: Aconitate hydratase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 677
Score = 62.5 bits (145), Expect = 1e-08
Identities = 34/104 (32%), Positives = 50/104 (48%)
Frame = +2
Query: 257 HQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVK 436
H + EN+A PG M+G+DSHTP D M + ++ P+V+ V+
Sbjct: 121 HNVHKENFAAPGKTMLGSDSHTPTPGGLGELAIGSGGLDVAVAMGGGAYYIEMPEVVNVR 180
Query: 437 LTGKLTGWTSPKDVILKVAGILTVREVPAPSWSTTDPGWTTSRV 568
L G+L W + KDVIL++ L+V+ T PG T V
Sbjct: 181 LEGELPEWATAKDVILELLRRLSVKGGVGKVLEYTGPGVETLTV 224
Score = 57.6 bits (133), Expect = 3e-07
Identities = 26/60 (43%), Positives = 39/60 (65%)
Frame = +1
Query: 481 LEGGRHPDCEGGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLK 660
LE R +GG G ++EY GPGV+ ++ TI NMG E+GAT+S+FP + + + YL+
Sbjct: 196 LELLRRLSVKGGVGKVLEYTGPGVETLTVPERTTITNMGTELGATSSIFPTDDQTKDYLE 255
>UniRef50_Q5K9V9 Cluster: Homoaconitase, mitochondrial precursor;
n=3; Dikarya|Rep: Homoaconitase, mitochondrial precursor
- Cryptococcus neoformans (Filobasidiella neoformans)
Length = 728
Score = 54.0 bits (124), Expect = 4e-06
Identities = 28/88 (31%), Positives = 48/88 (54%), Gaps = 1/88 (1%)
Frame = +2
Query: 257 HQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGV 433
HQII+E YA+PG +++ +DSH+ + DA + A + + P+++ V
Sbjct: 133 HQIIVEEGYAWPGKMVVASDSHSNHYGGVGCLGTAIVRTDAAGIWATGKFWWQIPRIVSV 192
Query: 434 KLTGKLTGWTSPKDVILKVAGILTVREV 517
L G+L+ + KDVI+ +AG+ EV
Sbjct: 193 SLDGRLSPGVTGKDVIVALAGLFNKDEV 220
Score = 40.3 bits (90), Expect = 0.053
Identities = 17/44 (38%), Positives = 26/44 (59%)
Frame = +1
Query: 523 AIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAY 654
A +E+ G GV+H+S TI NM E GA VFP + +++ +
Sbjct: 223 AAIEFTGSGVEHLSIDERLTIANMTTEWGAVAGVFPVDDKLKEW 266
>UniRef50_Q59PT1 Cluster: Putative uncharacterized protein; n=1;
Candida albicans|Rep: Putative uncharacterized protein -
Candida albicans (Yeast)
Length = 182
Score = 51.6 bits (118), Expect = 2e-05
Identities = 24/36 (66%), Positives = 28/36 (77%)
Frame = -1
Query: 632 YGNTLVVAPISAPMLQIVAMPVHEMWSTPGPWYSTM 525
YG VVAPISAP+LQIVA+PVH+ TP P YST+
Sbjct: 147 YGKVEVVAPISAPILQIVAIPVHDNVLTPSPKYSTI 182
>UniRef50_Q97Z42 Cluster: Aconitate hydratase; n=3; cellular
organisms|Rep: Aconitate hydratase - Sulfolobus
solfataricus
Length = 855
Score = 50.4 bits (115), Expect = 5e-05
Identities = 28/79 (35%), Positives = 42/79 (53%)
Frame = +2
Query: 281 AFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGW 460
AFP ++ IGTDSHT +A V+ P+ L P+VIGV+LTG++
Sbjct: 191 AFPEVI-IGTDSHTTMIEGLGILGWGVGGLEAEAVLLGEPYYLNVPEVIGVRLTGEIQEG 249
Query: 461 TSPKDVILKVAGILTVREV 517
+P DV+L + +L + V
Sbjct: 250 VTPTDVVLYITELLRKKNV 268
Score = 38.7 bits (86), Expect = 0.16
Identities = 18/44 (40%), Positives = 25/44 (56%)
Frame = +1
Query: 529 VEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLK 660
VE+ GP + +S ATI NM E GAT + FP + +YL+
Sbjct: 273 VEFFGPSLSLLSVPDRATIANMAPEYGATAAYFPIDDVTVSYLE 316
>UniRef50_Q0W1Q4 Cluster: 3-isopropylmalate dehydratase, large
subunit; n=2; Euryarchaeota|Rep: 3-isopropylmalate
dehydratase, large subunit - Uncultured methanogenic
archaeon RC-I
Length = 414
Score = 49.2 bits (112), Expect = 1e-04
Identities = 19/51 (37%), Positives = 31/51 (60%)
Frame = +1
Query: 508 EGGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLK 660
+G T +E++GP +DH+S G T+CNM E+G + P + + A+LK
Sbjct: 186 DGATYKAMEFYGPVIDHMSIAGRMTLCNMAIEMGGKAGIVPPDEKTFAFLK 236
Score = 47.6 bits (108), Expect = 3e-04
Identities = 24/80 (30%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
Frame = +2
Query: 257 HQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGV 433
HQ++ EN +A PG +++G DSH+ D ++ + + P+ I +
Sbjct: 101 HQLLPENGFAMPGKVIVGADSHSCTYGAFGAFATGVGATDMAEIYTSGKLWFRVPETIKL 160
Query: 434 KLTGKLTGWTSPKDVILKVA 493
+ GKL +PKDVIL++A
Sbjct: 161 TVDGKLPAAVTPKDVILRIA 180
>UniRef50_A2SQ03 Cluster: 3-isopropylmalate dehydratase; n=5;
Methanomicrobia|Rep: 3-isopropylmalate dehydratase -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 417
Score = 48.8 bits (111), Expect = 2e-04
Identities = 25/76 (32%), Positives = 36/76 (47%)
Frame = +2
Query: 257 HQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVK 436
HQI+ E PG +++G DSH+ D + A + P+ I +
Sbjct: 99 HQIMSEGVCLPGEIVVGADSHSCTLGALGAFSTGVGATDMAGIWATGGTWFRVPESISIV 158
Query: 437 LTGKLTGWTSPKDVIL 484
L+GKL+G T PKDV L
Sbjct: 159 LSGKLSGHTEPKDVAL 174
>UniRef50_A0HK99 Cluster: Aconitate hydratase-like; n=3;
Burkholderiales|Rep: Aconitate hydratase-like -
Comamonas testosteroni KF-1
Length = 659
Score = 48.0 bits (109), Expect = 3e-04
Identities = 24/76 (31%), Positives = 37/76 (48%)
Frame = +2
Query: 257 HQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVK 436
H ++ E YA PG L++GTDSHTP+ D + L P+ + +
Sbjct: 329 HAMMAECYALPGQLVVGTDSHTPHSGALGCVAFGIGTTDMANAFVTGAVRLTVPESLRIV 388
Query: 437 LTGKLTGWTSPKDVIL 484
L G+L+ + KDV+L
Sbjct: 389 LDGELSANVTAKDVVL 404
Score = 34.3 bits (75), Expect = 3.5
Identities = 14/38 (36%), Positives = 21/38 (55%)
Frame = +1
Query: 511 GGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSV 624
GG G + E+ G + +S AT+ NM AE+G T +
Sbjct: 416 GGVGKVFEFTGAAIARMSTDERATLTNMSAELGGFTGI 453
>UniRef50_Q125M5 Cluster: Aconitate hydratase-like; n=8;
Proteobacteria|Rep: Aconitate hydratase-like -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 888
Score = 47.6 bits (108), Expect = 3e-04
Identities = 28/74 (37%), Positives = 38/74 (51%)
Frame = +2
Query: 296 LMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKD 475
+MIGTDSHTP +A VM +P L+ P VIGV+LTG+L D
Sbjct: 203 MMIGTDSHTPMINGIGVLGWGVGGLEAQTVMFGMPTMLRIPDVIGVRLTGRLPPAAQSTD 262
Query: 476 VILKVAGILTVREV 517
+ L V L +R++
Sbjct: 263 LALTVT--LRLRQI 274
Score = 43.6 bits (98), Expect = 0.006
Identities = 20/50 (40%), Positives = 28/50 (56%)
Frame = +1
Query: 511 GGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLK 660
G +G VE++GPGV +S + + NM E GATT F + R YL+
Sbjct: 275 GVSGEFVEFYGPGVATLSAGDRSVVANMAPEYGATTGFFAVDQRTLDYLR 324
>UniRef50_Q4WUL6 Cluster: Homoaconitase, mitochondrial precursor;
n=10; Pezizomycotina|Rep: Homoaconitase, mitochondrial
precursor - Aspergillus fumigatus (Sartorya fumigata)
Length = 777
Score = 47.6 bits (108), Expect = 3e-04
Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 1/88 (1%)
Frame = +2
Query: 257 HQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGV 433
HQI++E YAFPG + + +DSH+ DA + A K P + V
Sbjct: 180 HQIMIEEGYAFPGTVTVASDSHSNMYGGVGCLGTPMVRTDAATIWATGRTWWKVPPIAKV 239
Query: 434 KLTGKLTGWTSPKDVILKVAGILTVREV 517
+ TG L + KDVI+ ++G+ EV
Sbjct: 240 QFTGTLPEGVTGKDVIVALSGLFNKDEV 267
>UniRef50_Q5PXM8 Cluster: Aconitase A; n=3; Gammaproteobacteria|Rep:
Aconitase A - Vibrio cholerae
Length = 407
Score = 47.2 bits (107), Expect = 5e-04
Identities = 26/89 (29%), Positives = 41/89 (46%)
Frame = +2
Query: 230 FLEARLWYFHQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWEL 409
F+ + HQ + E A G +++G+DSHT + V + N W++
Sbjct: 130 FVPPHIAVIHQYMREMMAGGGKMILGSDSHT-RYGALGTMAVGEGGGELVKQLLNDTWDI 188
Query: 410 KCPKVIGVKLTGKLTGWTSPKDVILKVAG 496
P V+ V LTGK + P+DV L + G
Sbjct: 189 DYPGVVAVHLTGKPAPYVGPQDVALAIIG 217
>UniRef50_Q4J9H0 Cluster: Aconitate hydratase; n=7; cellular
organisms|Rep: Aconitate hydratase - Sulfolobus
acidocaldarius
Length = 848
Score = 47.2 bits (107), Expect = 5e-04
Identities = 23/70 (32%), Positives = 38/70 (54%)
Frame = +2
Query: 281 AFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGW 460
A+P ++ IGTDSHTP +A VM P+ + P+V+GV+L G++
Sbjct: 188 AYPEIV-IGTDSHTPMTNGLGVLSWGVGGLEAEAVMLGEPYTMAVPEVVGVRLVGEIKEG 246
Query: 461 TSPKDVILKV 490
+P D++L +
Sbjct: 247 VTPTDIVLYI 256
Score = 42.3 bits (95), Expect = 0.013
Identities = 20/50 (40%), Positives = 28/50 (56%)
Frame = +1
Query: 508 EGGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYL 657
+G G VE+ GP + +++ ATI NM E GAT S FP + + YL
Sbjct: 263 KGVVGKFVEFFGPSLGNLTVPDRATIANMAPEYGATASYFPIDYQTLNYL 312
>UniRef50_P75764 Cluster: Uncharacterized protein ybhJ; n=32;
Bacteria|Rep: Uncharacterized protein ybhJ - Escherichia
coli (strain K12)
Length = 753
Score = 47.2 bits (107), Expect = 5e-04
Identities = 26/89 (29%), Positives = 41/89 (46%)
Frame = +2
Query: 230 FLEARLWYFHQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWEL 409
F+ + HQ + E A G +++G+DSHT + V + N W++
Sbjct: 122 FVPPHIAVIHQYMREMMAGGGKMILGSDSHT-RYGALGTMAVGEGGGELVKQLLNDTWDI 180
Query: 410 KCPKVIGVKLTGKLTGWTSPKDVILKVAG 496
P V+ V LTGK + P+DV L + G
Sbjct: 181 DYPGVVAVHLTGKPAPYVGPQDVALAIIG 209
>UniRef50_A5ZNE1 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 416
Score = 46.8 bits (106), Expect = 6e-04
Identities = 26/81 (32%), Positives = 40/81 (49%), Gaps = 1/81 (1%)
Frame = +2
Query: 257 HQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAV-DVMANIPWELKCPKVIGV 433
HQ+++ENY PG L+ G DSHT + D + ++ W L P+ +
Sbjct: 102 HQVMIENYVRPGELIFGADSHTCSYGALGAFGTGVGCTDFLYGMVTGTSWVL-VPESVKF 160
Query: 434 KLTGKLTGWTSPKDVILKVAG 496
LTGKL + +D+IL + G
Sbjct: 161 NLTGKLPEGVTARDLILTIIG 181
Score = 39.1 bits (87), Expect = 0.12
Identities = 16/45 (35%), Positives = 25/45 (55%)
Frame = +1
Query: 526 IVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLK 660
++E+ G G +S + T+CNM E GA T +F + + YLK
Sbjct: 192 VMEFTGEGAKTLSISDRMTLCNMAVEAGAKTGIFEADEKAMEYLK 236
>UniRef50_A7DAM6 Cluster: Aconitate hydratase domain protein; n=1;
Methylobacterium extorquens PA1|Rep: Aconitate hydratase
domain protein - Methylobacterium extorquens PA1
Length = 908
Score = 46.4 bits (105), Expect = 8e-04
Identities = 21/51 (41%), Positives = 29/51 (56%)
Frame = +1
Query: 508 EGGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLK 660
+G G VE++GPG+D + ATI NM E GAT FP + + +LK
Sbjct: 280 KGVVGKFVEFYGPGLDDMPVADRATISNMAPEYGATCGFFPIDQKTIDFLK 330
Score = 43.2 bits (97), Expect = 0.007
Identities = 27/79 (34%), Positives = 38/79 (48%)
Frame = +2
Query: 281 AFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGW 460
A+P L +GTDSHT +A M P + P+VIG KL+GKL
Sbjct: 205 AYPDSL-VGTDSHTTMVNGLAVLGWGVGGIEAEAAMLGQPLSMLIPEVIGFKLSGKLPEG 263
Query: 461 TSPKDVILKVAGILTVREV 517
T+ D++L V +L + V
Sbjct: 264 TTATDLVLTVTQMLRKKGV 282
>UniRef50_Q97VY2 Cluster: 3-isopropylmalate dehydratase large
subunit; n=10; Thermoprotei|Rep: 3-isopropylmalate
dehydratase large subunit - Sulfolobus solfataricus
Length = 416
Score = 46.4 bits (105), Expect = 8e-04
Identities = 27/90 (30%), Positives = 41/90 (45%), Gaps = 1/90 (1%)
Frame = +2
Query: 230 FLEARLWYFHQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXAD-AVDVMANIPWE 406
F + H++++E YA PG +++ DSHT +D A ++ W
Sbjct: 95 FYDINYGILHEVMIEQYANPGQVILAADSHTTTSGAVGAFAQGMGASDIAAALITGKTW- 153
Query: 407 LKCPKVIGVKLTGKLTGWTSPKDVILKVAG 496
L P+ V L GK W + KDV LK+ G
Sbjct: 154 LVVPQPFKVVLEGKPAKWITGKDVALKLLG 183
>UniRef50_Q9WYC7 Cluster: 3-isopropylmalate dehydratase large
subunit 1; n=8; cellular organisms|Rep:
3-isopropylmalate dehydratase large subunit 1 -
Thermotoga maritima
Length = 418
Score = 46.4 bits (105), Expect = 8e-04
Identities = 28/82 (34%), Positives = 36/82 (43%)
Frame = +2
Query: 257 HQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVK 436
HQI+ E Y PG L+ G DSHT D + K P+ I V
Sbjct: 100 HQILAEKYVKPGDLVAGADSHTCTAGGLGAFGTGMGSTDVAIIFGLGQNWFKVPETIKVV 159
Query: 437 LTGKLTGWTSPKDVILKVAGIL 502
+ GKL KD+IL++A IL
Sbjct: 160 VNGKLQDGVYAKDIILEIARIL 181
Score = 39.1 bits (87), Expect = 0.12
Identities = 18/60 (30%), Positives = 31/60 (51%)
Frame = +1
Query: 481 LEGGRHPDCEGGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLK 660
LE R +G T +E+HG +++++ TI NM E+GA + P + + +LK
Sbjct: 175 LEIARILGSDGATYKALEFHGSCIENMNVEDRLTISNMAVEVGAKAGLMPSDEKTREFLK 234
>UniRef50_Q58409 Cluster: 3-isopropylmalate dehydratase large
subunit 1; n=7; cellular organisms|Rep:
3-isopropylmalate dehydratase large subunit 1 -
Methanococcus jannaschii
Length = 420
Score = 46.4 bits (105), Expect = 8e-04
Identities = 26/78 (33%), Positives = 35/78 (44%)
Frame = +2
Query: 257 HQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVK 436
HQI+ ENY P + + G DSHT D + A +K PK I V
Sbjct: 99 HQILAENYVLPNMFVAGGDSHTCTHGAFGAFATGFGATDMAYIYATGETWIKVPKTIRVD 158
Query: 437 LTGKLTGWTSPKDVILKV 490
+ GK S KD++L+V
Sbjct: 159 IVGKNEN-VSAKDIVLRV 175
Score = 37.5 bits (83), Expect = 0.37
Identities = 20/57 (35%), Positives = 26/57 (45%)
Frame = +1
Query: 511 GGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLKFEPDAHD 681
G T +EY G V ++ G T+CNM E+G T V + YLK E D
Sbjct: 183 GATYMAIEYGGEVVKNMDMDGRLTLCNMAIEMGGKTGVIEADEITYDYLKKERGLSD 239
>UniRef50_Q9I3F5 Cluster: Aconitate hydratase 1; n=98; Bacteria|Rep:
Aconitate hydratase 1 - Pseudomonas aeruginosa
Length = 910
Score = 46.4 bits (105), Expect = 8e-04
Identities = 29/80 (36%), Positives = 38/80 (47%)
Frame = +2
Query: 278 YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLTG 457
YAFP L +GTDSHT +A M P + P+VIG KLTGKL
Sbjct: 202 YAFPDTL-VGTDSHTTMINGLGVLGWGVGGIEAEAAMLGQPVSMLIPEVIGFKLTGKLRE 260
Query: 458 WTSPKDVILKVAGILTVREV 517
+ D++L V +L + V
Sbjct: 261 GITATDLVLTVTQMLRKKGV 280
Score = 39.9 bits (89), Expect = 0.070
Identities = 19/51 (37%), Positives = 26/51 (50%)
Frame = +1
Query: 508 EGGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLK 660
+G G VE++G G+ + ATI NM E GAT FP + YL+
Sbjct: 278 KGVVGKFVEFYGDGLADLPLADRATIANMAPEYGATCGFFPVDEITLGYLR 328
>UniRef50_O53237 Cluster: 3-isopropylmalate dehydratase large
subunit; n=29; cellular organisms|Rep: 3-isopropylmalate
dehydratase large subunit - Mycobacterium tuberculosis
Length = 473
Score = 46.0 bits (104), Expect = 0.001
Identities = 20/55 (36%), Positives = 29/55 (52%)
Frame = +1
Query: 511 GGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLKFEPDA 675
GG G ++EY G ++ +S G TICNM E GA + + A+L+ P A
Sbjct: 202 GGQGHVIEYRGSAIESLSMEGRMTICNMSIEAGARAGMVAPDETTYAFLRGRPHA 256
>UniRef50_A6G875 Cluster: 3-isopropylmalate dehydratase; n=1;
Plesiocystis pacifica SIR-1|Rep: 3-isopropylmalate
dehydratase - Plesiocystis pacifica SIR-1
Length = 643
Score = 45.6 bits (103), Expect = 0.001
Identities = 26/86 (30%), Positives = 40/86 (46%)
Frame = +2
Query: 257 HQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVK 436
H+I++E+YA PG +++ TDSHTP + + PK + V
Sbjct: 320 HRIVVEDYARPGDIIVLTDSHTPTAGVMNAFAFGVGSTAMAFALRTGMIPVTVPKTVRVW 379
Query: 437 LTGKLTGWTSPKDVILKVAGILTVRE 514
+ G G SPKD++L + G RE
Sbjct: 380 VEGDAKGVLSPKDLVLHLIGDPFFRE 405
>UniRef50_O08451 Cluster: Aconitate hydratase; n=21; Bacteria|Rep:
Aconitate hydratase - Mycobacterium avium
Length = 961
Score = 45.6 bits (103), Expect = 0.001
Identities = 20/51 (39%), Positives = 28/51 (54%)
Frame = +1
Query: 511 GGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLKF 663
G G VE++G GV + AT+ NM E G+T ++FP + YLKF
Sbjct: 298 GVVGKFVEFYGEGVAEVPLANRATLGNMSPEFGSTAAIFPIDQETIDYLKF 348
Score = 37.9 bits (84), Expect = 0.28
Identities = 25/90 (27%), Positives = 40/90 (44%), Gaps = 2/90 (2%)
Frame = +2
Query: 236 EARLWYFHQIILENY--AFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWEL 409
+ + Y ++++E A+P +GTDSHT +A M P +
Sbjct: 205 QVNIEYLARVVMERVGVAYPDTC-VGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSM 263
Query: 410 KCPKVIGVKLTGKLTGWTSPKDVILKVAGI 499
P+V+G KLTG+ + DV+L V I
Sbjct: 264 LIPRVVGFKLTGEDPAPGAATDVVLTVTEI 293
>UniRef50_Q4T087 Cluster: Chromosome undetermined SCAF11289, whole
genome shotgun sequence; n=3; Euteleostomi|Rep:
Chromosome undetermined SCAF11289, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 894
Score = 45.2 bits (102), Expect = 0.002
Identities = 25/68 (36%), Positives = 35/68 (51%), Gaps = 1/68 (1%)
Frame = +1
Query: 511 GGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYL-KFEPDAHDIA 687
G G VE+ GPGV +S ATI NM E GAT + FP + YL + + +A
Sbjct: 265 GVVGKFVEFFGPGVARLSIADRATIANMCPEYGATAAFFPVDDASIRYLEQTGREPETLA 324
Query: 688 ATANFLQA 711
++L+A
Sbjct: 325 TVRDYLKA 332
Score = 37.5 bits (83), Expect = 0.37
Identities = 19/64 (29%), Positives = 31/64 (48%)
Frame = +2
Query: 299 MIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDV 478
++GTDSHT +A VM P + P+V+G +L+G G+ + D+
Sbjct: 194 VVGTDSHTTMIDGLGVLGWGVGGIEAEAVMLGQPISMVLPQVVGYRLSGVPDGFVTSTDI 253
Query: 479 ILKV 490
+L V
Sbjct: 254 VLTV 257
>UniRef50_A6DRT0 Cluster: 3-isopropylmalate dehydratase; n=4;
Bacteria|Rep: 3-isopropylmalate dehydratase -
Lentisphaera araneosa HTCC2155
Length = 433
Score = 45.2 bits (102), Expect = 0.002
Identities = 20/54 (37%), Positives = 29/54 (53%)
Frame = +1
Query: 511 GGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLKFEPD 672
G T +E+ GP +D +S TICNM E G V ++++EAY+K D
Sbjct: 195 GATYCAMEFEGPVIDELSIEERMTICNMAIEAGGKNGVIAADAKVEAYVKERTD 248
Score = 38.3 bits (85), Expect = 0.21
Identities = 24/70 (34%), Positives = 30/70 (42%)
Frame = +2
Query: 287 PGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTS 466
PG +++GTDSHT DA M LK P+ I L GKL
Sbjct: 120 PGEIILGTDSHTCTHGALGAFATGIGNTDAAFTMGTGRTWLKIPETIKFVLNGKLPKTMM 179
Query: 467 PKDVILKVAG 496
KD+IL + G
Sbjct: 180 AKDLILHMIG 189
>UniRef50_Q5V7D3 Cluster: Aconitate hydratase I; n=4; cellular
organisms|Rep: Aconitate hydratase I - Haloarcula
marismortui (Halobacterium marismortui)
Length = 927
Score = 45.2 bits (102), Expect = 0.002
Identities = 23/61 (37%), Positives = 35/61 (57%), Gaps = 3/61 (4%)
Frame = +1
Query: 511 GGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLKF---EPDAHD 681
G VE+ GPGV++++ ATI NM E G+T S+FP + + YL+ +PD D
Sbjct: 279 GVVDRFVEFFGPGVENLTVPDRATIANMAPEQGSTISMFPVDEQTLEYLELTGRDPDHVD 338
Query: 682 I 684
+
Sbjct: 339 L 339
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/73 (32%), Positives = 36/73 (49%)
Frame = +2
Query: 272 ENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKL 451
EN+ P L +GTDSHTP +A M P +K P+V+GV+L G+L
Sbjct: 200 ENWLLPDTL-VGTDSHTPMIGGIGVVGWGVGGIEAEAAMLGQPVTMKLPEVVGVRLEGEL 258
Query: 452 TGWTSPKDVILKV 490
+ D++L +
Sbjct: 259 PEGATATDLVLHI 271
>UniRef50_Q9RNH9 Cluster: Aconitase; n=3; Bacteria|Rep: Aconitase -
Streptomyces coelicolor
Length = 904
Score = 44.8 bits (101), Expect = 0.002
Identities = 25/74 (33%), Positives = 37/74 (50%)
Frame = +2
Query: 281 AFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGW 460
A+P L +GTDSHT +A M P + P+V+G KLTG+LT
Sbjct: 194 AYPDTL-VGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVGFKLTGELTPG 252
Query: 461 TSPKDVILKVAGIL 502
T+ D++L + +L
Sbjct: 253 TTATDLVLTITEML 266
Score = 43.6 bits (98), Expect = 0.006
Identities = 22/60 (36%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
Frame = +1
Query: 511 GGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLKFE-PDAHDIA 687
G G VE++G GV S ATI NM E G+T ++FP + Y++ AH +A
Sbjct: 270 GVVGKFVEFYGEGVAATSLANRATIGNMSPEFGSTAAIFPVDDETLNYMRLTGRSAHQVA 329
>UniRef50_Q59938 Cluster: Aconitate hydratase; n=356; cellular
organisms|Rep: Aconitate hydratase - Streptococcus
mutans
Length = 888
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/66 (36%), Positives = 31/66 (46%), Gaps = 1/66 (1%)
Frame = +1
Query: 508 EGGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLKF-EPDAHDI 684
E G VE+ GPG+ +S AT+ NM E GAT FP + Y+K A I
Sbjct: 269 ENVVGKFVEFFGPGLAGLSLADRATVANMAPEYGATCGYFPIDDETLNYMKLTNRSAEHI 328
Query: 685 AATANF 702
A T +
Sbjct: 329 ALTKEY 334
Score = 33.9 bits (74), Expect = 4.6
Identities = 26/96 (27%), Positives = 40/96 (41%), Gaps = 2/96 (2%)
Frame = +2
Query: 236 EARLWYFHQIIL--ENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWEL 409
+ L + +I+ + + +P M GTDSHT +A M
Sbjct: 177 QVNLEFLSDVIINKDGFLYPDS-MFGTDSHTTMINGIGVLGWGVGGIEAEAAMLGEASYF 235
Query: 410 KCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVREV 517
P+VIGV+L G+L + D+ LKV L + V
Sbjct: 236 PIPEVIGVRLYGELPKVATATDLALKVTQKLRLENV 271
>UniRef50_A5WEQ7 Cluster: 2-methylisocitrate dehydratase,
Fe/S-dependent; n=155; cellular organisms|Rep:
2-methylisocitrate dehydratase, Fe/S-dependent -
Psychrobacter sp. PRwf-1
Length = 903
Score = 44.4 bits (100), Expect = 0.003
Identities = 25/74 (33%), Positives = 37/74 (50%)
Frame = +2
Query: 281 AFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGW 460
A+P L +GTDSHTP +A VM P ++ P +IG++LTGKL
Sbjct: 222 AYPDTL-VGTDSHTPMVDALGVISIGVGGLEAESVMLGNPSYMRLPDIIGLELTGKLQPG 280
Query: 461 TSPKDVILKVAGIL 502
+ D++L + L
Sbjct: 281 ITGTDLVLAMTEFL 294
>UniRef50_P81291 Cluster: 3-isopropylmalate dehydratase large
subunit 2; n=3; cellular organisms|Rep:
3-isopropylmalate dehydratase large subunit 2 -
Methanococcus jannaschii
Length = 424
Score = 44.4 bits (100), Expect = 0.003
Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 1/90 (1%)
Frame = +2
Query: 230 FLEARLWYFHQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWE 406
F + R HQ++ E + PG +++G DSHT D V A
Sbjct: 94 FYDIREGVCHQVLPEKGHVAPGEVVVGADSHTCTHGAFGAFATGIGSTDMAHVFATGKLW 153
Query: 407 LKCPKVIGVKLTGKLTGWTSPKDVILKVAG 496
K P+ I +TG L + + KDVIL + G
Sbjct: 154 FKVPETIYFNITGDLQPYVTSKDVILSIIG 183
>UniRef50_P21399 Cluster: Iron-responsive element-binding protein 1;
n=116; cellular organisms|Rep: Iron-responsive
element-binding protein 1 - Homo sapiens (Human)
Length = 889
Score = 44.4 bits (100), Expect = 0.003
Identities = 26/68 (38%), Positives = 33/68 (48%), Gaps = 1/68 (1%)
Frame = +1
Query: 511 GGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYL-KFEPDAHDIA 687
G G VE+ GPGV +S ATI NM E GAT + FP + YL + D +
Sbjct: 272 GVVGKFVEFFGPGVAQLSIADRATIANMCPEYGATAAFFPVDEVSITYLVQTGRDEEKLK 331
Query: 688 ATANFLQA 711
+LQA
Sbjct: 332 YIKKYLQA 339
Score = 37.9 bits (84), Expect = 0.28
Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 2/87 (2%)
Frame = +2
Query: 236 EARLWYFHQIILEN--YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWEL 409
+ L Y +++ + Y +P L +GTDSHT +A VM P +
Sbjct: 179 QVNLEYLARVVFDQDGYYYPDSL-VGTDSHTTMIDGLGILGWGVGGIEAEAVMLGQPISM 237
Query: 410 KCPKVIGVKLTGKLTGWTSPKDVILKV 490
P+VIG +L GK + D++L +
Sbjct: 238 VLPQVIGYRLMGKPHPLVTSTDIVLTI 264
>UniRef50_Q7WB80 Cluster: Aconitate hydratase; n=3; Bordetella|Rep:
Aconitate hydratase - Bordetella parapertussis
Length = 894
Score = 44.0 bits (99), Expect = 0.004
Identities = 21/51 (41%), Positives = 29/51 (56%)
Frame = +1
Query: 508 EGGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLK 660
EG TG +VE+ G + +S ATI NM E GAT FP +++ YL+
Sbjct: 280 EGVTGCMVEFFGEALPGLSVADRATIANMAPEYGATCGFFPVDAQTLDYLR 330
>UniRef50_Q6A800 Cluster: 3-isopropylmalate dehydratase large
subunit; n=1; Propionibacterium acnes|Rep:
3-isopropylmalate dehydratase large subunit -
Propionibacterium acnes
Length = 135
Score = 44.0 bits (99), Expect = 0.004
Identities = 21/55 (38%), Positives = 27/55 (49%)
Frame = +1
Query: 511 GGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLKFEPDA 675
GG G +VEY G ++ +S G TICNM E G + + YLK P A
Sbjct: 30 GGQGHMVEYRGEAIEKMSMEGRMTICNMSIEWGVRVGMVASDETTFTYLKDRPHA 84
>UniRef50_Q42560 Cluster: Aconitate hydratase 1; n=35; cellular
organisms|Rep: Aconitate hydratase 1 - Arabidopsis
thaliana (Mouse-ear cress)
Length = 898
Score = 44.0 bits (99), Expect = 0.004
Identities = 22/57 (38%), Positives = 28/57 (49%)
Frame = +1
Query: 511 GGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLKFEPDAHD 681
G G VE+HG G+ +S ATI NM E GAT FP + YL+ + D
Sbjct: 276 GVVGKFVEFHGEGMRELSLADRATIANMSPEYGATMGFFPVDHVTLQYLRLTGRSDD 332
Score = 39.9 bits (89), Expect = 0.070
Identities = 22/68 (32%), Positives = 31/68 (45%)
Frame = +2
Query: 299 MIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDV 478
++GTDSHT +A M P + P V+G KLTGKL + D+
Sbjct: 205 VVGTDSHTTMIDGLGVAGWGVGGIEAEATMLGQPMSMVLPGVVGFKLTGKLRDGMTATDL 264
Query: 479 ILKVAGIL 502
+L V +L
Sbjct: 265 VLTVTQML 272
>UniRef50_A5ZND9 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 423
Score = 43.6 bits (98), Expect = 0.006
Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Frame = +2
Query: 257 HQIILE-NYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGV 433
HQ++ E Y PG ++ GTDSHT + ++ +K P+ I V
Sbjct: 110 HQLMTEAGYVKPGNIVFGTDSHTTTYGCVGAFSSGIGYTEMASILGTGTMWIKVPETIKV 169
Query: 434 KLTGKLTGWTSPKDVILKVAGIL 502
+ G+L KDVIL++ G L
Sbjct: 170 VIDGELPANVMSKDVILRLIGDL 192
>UniRef50_Q8TVF2 Cluster: 3-isopropylmalate dehydratase large
subunit 1; n=3; cellular organisms|Rep:
3-isopropylmalate dehydratase large subunit 1 -
Methanopyrus kandleri
Length = 418
Score = 43.6 bits (98), Expect = 0.006
Identities = 27/90 (30%), Positives = 40/90 (44%), Gaps = 1/90 (1%)
Frame = +2
Query: 230 FLEARLWYFHQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWE 406
F + R HQ++ E + PG +++G DSHT D V A
Sbjct: 93 FYDVREGVCHQVLPEKGHVRPGDVIVGADSHTCTHGALGAFATGIGSTDMAAVFATGKLW 152
Query: 407 LKCPKVIGVKLTGKLTGWTSPKDVILKVAG 496
+ P+ V++TG+L KDV+LKV G
Sbjct: 153 FRVPETYRVEITGELPEGVYAKDVVLKVTG 182
Score = 41.1 bits (92), Expect = 0.030
Identities = 18/51 (35%), Positives = 28/51 (54%)
Frame = +1
Query: 508 EGGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLK 660
+G T +EYHG V +S + +CNM E+GA T + P + + Y+K
Sbjct: 187 DGATYMAIEYHGEVVREMSVSDRMCLCNMAIEMGAKTGMVPPDEKTLEYVK 237
>UniRef50_Q5A379 Cluster: Putative uncharacterized protein; n=1;
Candida albicans|Rep: Putative uncharacterized protein -
Candida albicans (Yeast)
Length = 115
Score = 43.2 bits (97), Expect = 0.007
Identities = 26/82 (31%), Positives = 40/82 (48%)
Frame = -1
Query: 254 NTRAGLPETDSIFSSGSL*KLVYFFVEVLSPGQILLASDLGFDQVITMNGGRYSYTGKAG 75
NT PET IF + S ++V F V+V GQI ++L DQ++T++
Sbjct: 3 NTGTWFPETQVIFGTSSGQEIVNFLVQVNGSGQIFWTTNLSLDQMVTVDSRWSGNLWNTS 62
Query: 74 RDKL*HCHLCSGVLHGHTVGTQ 9
KL + HL +L + V +Q
Sbjct: 63 GHKLQNGHLGGSILTSNPVWSQ 84
>UniRef50_UPI00015BAFD3 Cluster: 3-isopropylmalate dehydratase; n=1;
Ignicoccus hospitalis KIN4/I|Rep: 3-isopropylmalate
dehydratase - Ignicoccus hospitalis KIN4/I
Length = 429
Score = 42.7 bits (96), Expect = 0.010
Identities = 27/84 (32%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +2
Query: 257 HQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXAD-AVDVMANIPWELKCPKVIG 430
HQ+++E A+PG + +G DSHT D A+ +M W K P+ +
Sbjct: 102 HQVMVEEGRAWPGSVFVGADSHTVTYGALGSFATGVGSTDAAIAMMTGRIW-FKVPEALK 160
Query: 431 VKLTGKLTGWTSPKDVILKVAGIL 502
L GK KD+ILK+ G L
Sbjct: 161 FNLIGKFREGVMSKDLILKIIGDL 184
>UniRef50_UPI0000E49144 Cluster: PREDICTED: similar to Aconitase 2,
mitochondrial; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to Aconitase 2, mitochondrial -
Strongylocentrotus purpuratus
Length = 632
Score = 42.7 bits (96), Expect = 0.010
Identities = 22/36 (61%), Positives = 26/36 (72%)
Frame = +1
Query: 592 MGAEIGATTSVFPYNSRMEAYLKFEPDAHDIAATAN 699
MGAEIGATTS+FP+NSRM YL D +IA A+
Sbjct: 1 MGAEIGATTSMFPFNSRMRDYL-VATDRSEIADLAD 35
>UniRef50_Q5FUG3 Cluster: 3-isopropylmalate dehydratase large
subunit; n=120; Bacteria|Rep: 3-isopropylmalate
dehydratase large subunit - Gluconobacter oxydans
(Gluconobacter suboxydans)
Length = 475
Score = 42.7 bits (96), Expect = 0.010
Identities = 19/55 (34%), Positives = 28/55 (50%)
Frame = +1
Query: 511 GGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLKFEPDA 675
GGTG ++E+ G + + G T+CNM E GA + + AY+K P A
Sbjct: 200 GGTGHVIEFAGSAIRDLDMAGRMTLCNMSIEAGARAGLVAPDETTFAYVKGRPFA 254
>UniRef50_Q1IMD4 Cluster: Aconitate hydratase-like; n=1;
Acidobacteria bacterium Ellin345|Rep: Aconitate
hydratase-like - Acidobacteria bacterium (strain
Ellin345)
Length = 655
Score = 42.3 bits (95), Expect = 0.013
Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 1/88 (1%)
Frame = +2
Query: 257 HQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGV 433
HQI++E Y P ++ +DSH+ DA + A + P+ I V
Sbjct: 104 HQIMVERGYVVPESFVVASDSHSNMYGAMGAIGTPVVRTDAAAIWATGEFWWSIPRTIQV 163
Query: 434 KLTGKLTGWTSPKDVILKVAGILTVREV 517
L GKL + KDVI+ +AG+ EV
Sbjct: 164 VLEGKLRPGVTGKDVIITLAGLYNKDEV 191
>UniRef50_A7CSQ0 Cluster: Aconitate hydratase 1; n=1; Opitutaceae
bacterium TAV2|Rep: Aconitate hydratase 1 - Opitutaceae
bacterium TAV2
Length = 965
Score = 42.3 bits (95), Expect = 0.013
Identities = 19/47 (40%), Positives = 25/47 (53%)
Frame = +1
Query: 520 GAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLK 660
G VE++GPG + ATI NM E GAT FP ++ YL+
Sbjct: 283 GKFVEFYGPGAAALPVVDRATIANMAPEYGATMGFFPIDAECTNYLR 329
>UniRef50_A6FCI8 Cluster: Isopropylmalate isomerase large subunit;
n=1; Moritella sp. PE36|Rep: Isopropylmalate isomerase
large subunit - Moritella sp. PE36
Length = 468
Score = 42.3 bits (95), Expect = 0.013
Identities = 18/50 (36%), Positives = 26/50 (52%)
Frame = +1
Query: 511 GGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLK 660
GG G ++EY G V +S T+CNM E GA+ + + +YLK
Sbjct: 195 GGQGCVIEYTGEAVSQLSMEQRMTLCNMTVEAGASAGIISPDQTTVSYLK 244
>UniRef50_A5C294 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 885
Score = 42.3 bits (95), Expect = 0.013
Identities = 21/50 (42%), Positives = 26/50 (52%)
Frame = +1
Query: 511 GGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLK 660
G G VE++G G+ +S ATI NM E GAT FP + YLK
Sbjct: 248 GVVGKFVEFYGEGMRELSLADRATIANMSPEYGATMGFFPVDHVTLQYLK 297
Score = 39.1 bits (87), Expect = 0.12
Identities = 25/91 (27%), Positives = 40/91 (43%), Gaps = 2/91 (2%)
Frame = +2
Query: 236 EARLWYFHQIIL--ENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWEL 409
+ L Y +++ E +P + +GTDSHT +A M P +
Sbjct: 155 QVNLEYLGRVVFNTEGILYPDSV-VGTDSHTTMIDGLGVAGWGVGGIEAEAAMLGQPMSM 213
Query: 410 KCPKVIGVKLTGKLTGWTSPKDVILKVAGIL 502
P V+G KL+GKL + D++L V +L
Sbjct: 214 VLPGVVGFKLSGKLRDGVTATDLVLTVTQML 244
>UniRef50_Q2GN26 Cluster: Homoaconitase, mitochondrial precursor;
n=9; Pezizomycotina|Rep: Homoaconitase, mitochondrial
precursor - Chaetomium globosum (Soil fungus)
Length = 797
Score = 42.3 bits (95), Expect = 0.013
Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 1/88 (1%)
Frame = +2
Query: 257 HQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGV 433
HQI++E YA+PG L + +DSH+ DA + A + P + V
Sbjct: 182 HQIMIEEGYAWPGTLTVASDSHSNMYGGVAALGTPVVRTDAASIWATGQTWWQIPPIAKV 241
Query: 434 KLTGKLTGWTSPKDVILKVAGILTVREV 517
TG L + KDVI+ + + EV
Sbjct: 242 TFTGVLPRGVTGKDVIIALCALFNQDEV 269
>UniRef50_Q5P0Q2 Cluster: Aconitase; n=4; Proteobacteria|Rep:
Aconitase - Azoarcus sp. (strain EbN1) (Aromatoleum
aromaticum (strain EbN1))
Length = 905
Score = 41.9 bits (94), Expect = 0.017
Identities = 18/47 (38%), Positives = 26/47 (55%)
Frame = +1
Query: 520 GAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLK 660
G VE+ G G ++ T AT+ NM E GAT FP + + AY++
Sbjct: 283 GKFVEFFGEGTASLTVTDRATLANMAPEYGATMGFFPIDDKTVAYMR 329
Score = 36.7 bits (81), Expect = 0.65
Identities = 22/73 (30%), Positives = 33/73 (45%)
Frame = +2
Query: 299 MIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDV 478
++GTDSHT +A M P L P V+GV+L G+L + D+
Sbjct: 209 LVGTDSHTTMINGLGVVGWGVGGIEAEAGMLGQPVYLLTPDVVGVELKGRLNEGVTATDL 268
Query: 479 ILKVAGILTVREV 517
+L V +L +V
Sbjct: 269 VLTVTELLRRHKV 281
>UniRef50_A4FHT3 Cluster: Aconitate hydratase 1; n=2;
Actinomycetales|Rep: Aconitate hydratase 1 -
Saccharopolyspora erythraea (strain NRRL 23338)
Length = 711
Score = 41.9 bits (94), Expect = 0.017
Identities = 26/83 (31%), Positives = 34/83 (40%)
Frame = +2
Query: 308 TDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILK 487
TDSHTP A M P ++ P V+GV+LTG+L + D+ L
Sbjct: 31 TDSHTPMVNSIGVLGWGVGGLQAQAAMVGEPTAIRFPTVVGVRLTGRLRSGVTATDLALT 90
Query: 488 VAGILTVREVPAPSWSTTDPGWT 556
V +L V T PG T
Sbjct: 91 VTELLRAHGVVDKFVEFTGPGAT 113
Score = 40.7 bits (91), Expect = 0.040
Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 1/84 (1%)
Frame = +1
Query: 511 GGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLKFEP-DAHDIA 687
G VE+ GPG + A + NM E GAT + FP++ +YL+ A
Sbjct: 99 GVVDKFVEFTGPGATGLGWAARAAVSNMAPEYGATCAFFPFDDEAMSYLELTARSPEQRA 158
Query: 688 ATANFLQATCSTARQQRHPMNQFD 759
A +L+A R+ P+ ++D
Sbjct: 159 VVAAYLRAQ-GLYRRAGDPVPRYD 181
>UniRef50_Q0ZQ48 Cluster: FrbA; n=6; cellular organisms|Rep: FrbA -
Streptomyces rubellomurinus
Length = 886
Score = 41.5 bits (93), Expect = 0.023
Identities = 20/50 (40%), Positives = 26/50 (52%)
Frame = +1
Query: 511 GGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLK 660
G G VE+ GPGV +S AT+ NM E G T + FP + YL+
Sbjct: 281 GVVGRFVEFFGPGVCALSVPDRATLSNMAPEYGCTVAFFPVDDTTLRYLE 330
Score = 37.9 bits (84), Expect = 0.28
Identities = 22/68 (32%), Positives = 33/68 (48%)
Frame = +2
Query: 299 MIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDV 478
++GTDSHTP +A V+ L P+VIGV+LTG+L ++ D+
Sbjct: 210 VLGTDSHTPMVGALGVLGWGVGGIEAETVLLGHSVSLLSPQVIGVRLTGELPVGSTATDL 269
Query: 479 ILKVAGIL 502
L + L
Sbjct: 270 ALTMTEFL 277
>UniRef50_Q0ADB7 Cluster: Aconitate hydratase 1; n=5; Bacteria|Rep:
Aconitate hydratase 1 - Nitrosomonas eutropha (strain
C71)
Length = 947
Score = 41.5 bits (93), Expect = 0.023
Identities = 20/48 (41%), Positives = 25/48 (52%)
Frame = +1
Query: 520 GAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLKF 663
G VE+ G GV +S ATI NM E GAT FP + AY ++
Sbjct: 279 GKFVEFFGEGVTLLSLPDRATIANMAPEYGATMGFFPVDDATLAYFRY 326
Score = 35.9 bits (79), Expect = 1.1
Identities = 23/77 (29%), Positives = 33/77 (42%)
Frame = +2
Query: 272 ENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKL 451
+ + +P L +GTDSHT +A M P P V+GV LTG L
Sbjct: 197 DGFIYPDTL-VGTDSHTTMINGIGVVGWGVGGIEAEAGMLGQPIYFLTPDVVGVNLTGHL 255
Query: 452 TGWTSPKDVILKVAGIL 502
+ D++L V +L
Sbjct: 256 QEGVTATDLVLTVTEML 272
>UniRef50_P49367 Cluster: Homoaconitase, mitochondrial precursor;
n=14; Dikarya|Rep: Homoaconitase, mitochondrial
precursor - Saccharomyces cerevisiae (Baker's yeast)
Length = 693
Score = 41.5 bits (93), Expect = 0.023
Identities = 26/88 (29%), Positives = 41/88 (46%), Gaps = 1/88 (1%)
Frame = +2
Query: 257 HQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGV 433
HQI++E YAFP + + +DSH+ DA + A + P V V
Sbjct: 123 HQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQV 182
Query: 434 KLTGKLTGWTSPKDVILKVAGILTVREV 517
+L G+L S KD+I+ + G+ +V
Sbjct: 183 ELKGQLPQGVSGKDIIVALCGLFNNDQV 210
>UniRef50_Q65VS0 Cluster: 3-isopropylmalate dehydratase large
subunit 1; n=7; Proteobacteria|Rep: 3-isopropylmalate
dehydratase large subunit 1 - Mannheimia
succiniciproducens (strain MBEL55E)
Length = 475
Score = 41.5 bits (93), Expect = 0.023
Identities = 19/56 (33%), Positives = 29/56 (51%)
Frame = +1
Query: 508 EGGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLKFEPDA 675
+G T +E+ G +D +S G TICNM E GA + + ++ Y+K P A
Sbjct: 200 DGATNYAIEFCGEVIDELSVEGRMTICNMAVECGARGAFMAPDEKVYEYIKGTPRA 255
Score = 33.1 bits (72), Expect = 8.0
Identities = 21/71 (29%), Positives = 32/71 (45%)
Frame = +2
Query: 272 ENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKL 451
+ A PG+++ DSHT ++ ++A K K + V LTGKL
Sbjct: 121 QGLALPGMVIAAGDSHTTTYGAFGAFGFGIGTSEIEHLLATQTLVYKKLKNMRVTLTGKL 180
Query: 452 TGWTSPKDVIL 484
T+ KDVI+
Sbjct: 181 PFGTTAKDVIM 191
>UniRef50_Q8NQ98 Cluster: Aconitate hydratase; n=10; Bacteria|Rep:
Aconitate hydratase - Corynebacterium glutamicum
(Brevibacterium flavum)
Length = 939
Score = 41.5 bits (93), Expect = 0.023
Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Frame = +2
Query: 236 EARLWYFHQIILEN--YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWEL 409
+ + Y +++ +N A+P IGTDSHT +A M P +
Sbjct: 179 QVNIEYLARVVFDNEGLAYPDTC-IGTDSHTTMENGLGILGWGVGGIEAEAAMLGQPVSM 237
Query: 410 KCPKVIGVKLTGKLTGWTSPKDVILKVAGIL 502
P+V+G KLTG++ + DV+L + +L
Sbjct: 238 LIPRVVGFKLTGEIPVGVTATDVVLTITEML 268
Score = 39.1 bits (87), Expect = 0.12
Identities = 17/44 (38%), Positives = 25/44 (56%)
Frame = +1
Query: 529 VEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLK 660
VE++G GV + ATI NM E G+T ++FP + YL+
Sbjct: 278 VEFYGSGVKAVPLANRATIGNMSPEFGSTCAMFPIDEETTKYLR 321
>UniRef50_A4M821 Cluster: Homoaconitate hydratase family protein;
n=5; Bacteria|Rep: Homoaconitate hydratase family
protein - Petrotoga mobilis SJ95
Length = 419
Score = 41.1 bits (92), Expect = 0.030
Identities = 31/106 (29%), Positives = 46/106 (43%), Gaps = 1/106 (0%)
Frame = +2
Query: 191 QVFRDCRS*IWSRFLEARLWYFHQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXX 367
++ RD S ++F + HQ++ E +A PG ++IG DSHT
Sbjct: 81 KLMRDFSSNYGTKFYDIGEGICHQLMPEKGHALPGQIVIGADSHTCTYGALNCFSTGVGS 140
Query: 368 ADAVDVMANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILT 505
D MA+ K P+ I + L G L+ KDV L V +T
Sbjct: 141 TDLAIAMASGKLWFKVPQSIKIVLEGSLSKGIYSKDVALYVIKNMT 186
Score = 39.5 bits (88), Expect = 0.092
Identities = 18/54 (33%), Positives = 28/54 (51%)
Frame = +1
Query: 511 GGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLKFEPD 672
G T VE+ GP +D++S TI NM E+GA + + + E ++K D
Sbjct: 189 GATYKAVEFEGPVIDNLSVEARFTISNMSVEMGAKVGLMKLDEKAENWIKERTD 242
>UniRef50_Q8TW29 Cluster: 3-isopropylmalate dehydratase large
subunit 2; n=1; Methanopyrus kandleri|Rep:
3-isopropylmalate dehydratase large subunit 2 -
Methanopyrus kandleri
Length = 402
Score = 40.7 bits (91), Expect = 0.040
Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Frame = +2
Query: 257 HQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGV 433
HQ+++E YA PG ++ G DSHTP D + ++ P+ + V
Sbjct: 100 HQVLVEEGYAGPGRVVFGGDSHTPTSGAASALAFGFGGTDMAFALLYGELWIRVPRTVRV 159
Query: 434 KLTGKLTGWTSPKDVILKVAGIL 502
+ G+L + KD+ L V G L
Sbjct: 160 HVEGELEEPATAKDLALTVVGEL 182
>UniRef50_Q89X98 Cluster: 3-isopropylmalate dehydratase large
subunit 1; n=52; Bacteria|Rep: 3-isopropylmalate
dehydratase large subunit 1 - Bradyrhizobium japonicum
Length = 477
Score = 40.7 bits (91), Expect = 0.040
Identities = 20/60 (33%), Positives = 28/60 (46%)
Frame = +1
Query: 496 HPDCEGGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLKFEPDA 675
H GGTG VEY G + + G TICN+ E+GA + + Y++ P A
Sbjct: 200 HVGAAGGTGYAVEYAGSAIRGMPIEGRLTICNLSVELGAKMGLIAPDQTTFDYVRGRPYA 259
>UniRef50_A5WGT5 Cluster: 3-isopropylmalate dehydratase, large
subunit; n=11; Bacteria|Rep: 3-isopropylmalate
dehydratase, large subunit - Psychrobacter sp. PRwf-1
Length = 478
Score = 40.3 bits (90), Expect = 0.053
Identities = 19/55 (34%), Positives = 28/55 (50%)
Frame = +1
Query: 511 GGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLKFEPDA 675
GGTG +E+ G +++S G T+CNM E GA + + Y+K P A
Sbjct: 207 GGTGYAIEFAGEVFENMSMEGRMTVCNMAIEAGARVGMVGVDETTIEYVKGRPFA 261
>UniRef50_A7NXJ3 Cluster: Chromosome chr5 scaffold_2, whole genome
shotgun sequence; n=8; Magnoliophyta|Rep: Chromosome
chr5 scaffold_2, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 507
Score = 40.3 bits (90), Expect = 0.053
Identities = 22/79 (27%), Positives = 37/79 (46%)
Frame = +2
Query: 272 ENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKL 451
E + PG +++GTDSHT DA V+ LK P + + G++
Sbjct: 202 EGHCRPGEVLLGTDSHTCTAGAFGQFATGIGNTDAAFVLGTGKILLKVPPTLRFVMDGEM 261
Query: 452 TGWTSPKDVILKVAGILTV 508
+ KD+IL++ G ++V
Sbjct: 262 PNYLLAKDLILQIIGEISV 280
>UniRef50_Q2GXH4 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 605
Score = 40.3 bits (90), Expect = 0.053
Identities = 22/79 (27%), Positives = 36/79 (45%)
Frame = +2
Query: 263 IILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLT 442
++ E +A+PG + + +DSH + DA + A P + V+LT
Sbjct: 132 MVEEGHAWPGTMAVASDSHGTHYGGVGCLGTPVVRTDACSICATDRTWCNVPPIARVRLT 191
Query: 443 GKLTGWTSPKDVILKVAGI 499
G L + KDVI+ + GI
Sbjct: 192 GTLPQGVTGKDVIVALCGI 210
>UniRef50_Q6NH63 Cluster: Aconitate hydratase; n=32; cellular
organisms|Rep: Aconitate hydratase - Corynebacterium
diphtheriae
Length = 934
Score = 40.3 bits (90), Expect = 0.053
Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 2/83 (2%)
Frame = +2
Query: 260 QIILEN--YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGV 433
+++ +N A+P IGTDSHT +A M P + P+V+G
Sbjct: 187 RVVFDNNGLAYPDTC-IGTDSHTTMENGLGILGWGVGGIEAEAAMLGQPVSMLIPRVVGF 245
Query: 434 KLTGKLTGWTSPKDVILKVAGIL 502
KLTG++ + DV+L + +L
Sbjct: 246 KLTGEIPAGVTATDVVLTITEML 268
Score = 38.3 bits (85), Expect = 0.21
Identities = 17/43 (39%), Positives = 24/43 (55%)
Frame = +1
Query: 529 VEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYL 657
VE++G GV I ATI NM E G+T ++FP + Y+
Sbjct: 278 VEFYGNGVKSIPLANRATIGNMSPEFGSTCAIFPIDEETVKYM 320
>UniRef50_Q9RTY9 Cluster: 3-isopropylmalate dehydratase large
subunit 1; n=10; Bacteria|Rep: 3-isopropylmalate
dehydratase large subunit 1 - Deinococcus radiodurans
Length = 434
Score = 39.9 bits (89), Expect = 0.070
Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Frame = +2
Query: 257 HQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGV 433
HQ+++E A PG +++G+DSH+ D A+ L+ P+ + V
Sbjct: 117 HQVLMEEKLAQPGWIVLGSDSHSTTYGAVAAFGSGMGATDIALAAASGKTWLRVPESVKV 176
Query: 434 KLTGKLTGWTSPKDVILKVAGIL 502
LTG L + KDV L++ +L
Sbjct: 177 TLTGDLRPGVTAKDVALEMIRVL 199
>UniRef50_A3BB05 Cluster: Putative uncharacterized protein; n=1;
Oryza sativa (japonica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. japonica
(Rice)
Length = 696
Score = 39.5 bits (88), Expect = 0.092
Identities = 24/70 (34%), Positives = 32/70 (45%)
Frame = +1
Query: 511 GGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLKFEPDAHDIAA 690
G G VE++G GV +S ATI NM E GA+ FP + YL+ H
Sbjct: 130 GVVGKFVEFYGVGVGELSLPARATIANMSPEYGASMGFFPVDH--YNYLRKISSFHTRLI 187
Query: 691 TANFLQATCS 720
+ L TC+
Sbjct: 188 KQHNLAITCT 197
>UniRef50_Q82WI9 Cluster: 3-isopropylmalate dehydratase large
subunit; n=81; cellular organisms|Rep: 3-isopropylmalate
dehydratase large subunit - Nitrosomonas europaea
Length = 470
Score = 39.5 bits (88), Expect = 0.092
Identities = 19/55 (34%), Positives = 27/55 (49%)
Frame = +1
Query: 511 GGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLKFEPDA 675
GGTG +E+ G + +S G T+CNM E GA + + Y+K P A
Sbjct: 197 GGTGYAIEFAGSAIRSLSMEGRMTLCNMAIEAGARAGMVGADEVTIDYIKGRPFA 251
>UniRef50_Q1AVC5 Cluster: Homoaconitate hydratase family protein;
n=2; Bacteria|Rep: Homoaconitate hydratase family
protein - Rubrobacter xylanophilus (strain DSM 9941 /
NBRC 16129)
Length = 424
Score = 39.1 bits (87), Expect = 0.12
Identities = 18/54 (33%), Positives = 25/54 (46%)
Frame = +1
Query: 511 GGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLKFEPD 672
GG A++E+ G G +S + NM E GA T +FP + YL D
Sbjct: 189 GGANAVLEFVGEGAASLSLDDRLAVANMAVEAGAETGIFPADEVTARYLDRRAD 242
Score = 33.1 bits (72), Expect = 8.0
Identities = 21/79 (26%), Positives = 36/79 (45%), Gaps = 1/79 (1%)
Frame = +2
Query: 257 HQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGV 433
H +++E+ + PG+++ G DSHT D +A + + P I V
Sbjct: 103 HTVLVEDGWIVPGMVIAGGDSHTCTYGALGAFGTGLGSTDIAACLAFGEFWQQVPGTIQV 162
Query: 434 KLTGKLTGWTSPKDVILKV 490
+ TG + + KD+IL V
Sbjct: 163 EFTGHKGSFVAGKDLILAV 181
>UniRef50_A4VXS4 Cluster: 3-isopropylmalate dehydratase large
subunit; n=2; Streptococcus suis|Rep: 3-isopropylmalate
dehydratase large subunit - Streptococcus suis (strain
05ZYH33)
Length = 439
Score = 39.1 bits (87), Expect = 0.12
Identities = 19/53 (35%), Positives = 27/53 (50%)
Frame = +1
Query: 502 DCEGGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLK 660
DC G G +VE+ GP +D +S TICNM E G+ + + YL+
Sbjct: 194 DC--GLGHVVEFAGPVIDRLSMEERMTICNMSIEFGSKMGIMAPDQTTFDYLR 244
>UniRef50_Q9RTI6 Cluster: 3-isopropylmalate dehydratase large
subunit 2; n=3; Bacteria|Rep: 3-isopropylmalate
dehydratase large subunit 2 - Deinococcus radiodurans
Length = 431
Score = 39.1 bits (87), Expect = 0.12
Identities = 24/79 (30%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
Frame = +2
Query: 263 IILENYAF--PGLLMIGTDSHTPNXXXXXXXXXXXXXAD-AVDVMANIPWELKCPKVIGV 433
++LEN PG ++ DSHT N D A + A W K P+ + +
Sbjct: 105 VVLENTGLMKPGQTLVSGDSHTCNAGALGAFATGVGSTDLAGAIYAGKVW-FKVPETMLI 163
Query: 434 KLTGKLTGWTSPKDVILKV 490
++TGK +PKD++L+V
Sbjct: 164 RVTGKTNPGVTPKDIVLEV 182
>UniRef50_Q18GT3 Cluster: 3-isopropylmalate dehydratase large
subunit; n=2; cellular organisms|Rep: 3-isopropylmalate
dehydratase large subunit - Haloquadratum walsbyi
(strain DSM 16790)
Length = 488
Score = 38.7 bits (86), Expect = 0.16
Identities = 19/60 (31%), Positives = 27/60 (45%), Gaps = 3/60 (5%)
Frame = +1
Query: 511 GGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLK---FEPDAHD 681
GG G + EY G ++++ G +CNM E GA + YLK + PD D
Sbjct: 198 GGVGHVYEYGGEAIENLDMEGRLAVCNMSIEGGARAGYINPDQTTYEYLKGREYAPDVDD 257
>UniRef50_P07264 Cluster: 3-isopropylmalate dehydratase; n=473;
cellular organisms|Rep: 3-isopropylmalate dehydratase -
Saccharomyces cerevisiae (Baker's yeast)
Length = 779
Score = 38.7 bits (86), Expect = 0.16
Identities = 16/53 (30%), Positives = 26/53 (49%)
Frame = +1
Query: 511 GGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLKFEP 669
GGTG ++E+ G ++ +S ++CNM E GA + + Y K P
Sbjct: 208 GGTGCVIEFAGEAIEALSMEARMSMCNMAIEAGARAGMIKPDETTFQYTKGRP 260
>UniRef50_Q0C395 Cluster: Putative 3-isopropylmalate dehydratase,
large subunit; n=1; Hyphomonas neptunium ATCC 15444|Rep:
Putative 3-isopropylmalate dehydratase, large subunit -
Hyphomonas neptunium (strain ATCC 15444)
Length = 463
Score = 38.3 bits (85), Expect = 0.21
Identities = 16/54 (29%), Positives = 27/54 (50%)
Frame = +1
Query: 508 EGGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLKFEP 669
+GG +EY G + +S G T+CNM E A T++ +++ Y+ P
Sbjct: 195 DGGKRCAIEYAGEAISDLSIEGRLTLCNMAVEFAAFTALIAPDAKTLDYVSGRP 248
Score = 33.1 bits (72), Expect = 8.0
Identities = 19/70 (27%), Positives = 32/70 (45%)
Frame = +2
Query: 281 AFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKLTGW 460
A PGL ++ DSHT + +DA MA P+ + +++ G+L+
Sbjct: 119 ALPGLTLVCPDSHTCSLGALGALAWGIGSSDAEHAMATGTLRAAKPRQMLIRVAGRLSPG 178
Query: 461 TSPKDVILKV 490
S KD+ L +
Sbjct: 179 VSAKDLALYI 188
>UniRef50_Q8KER8 Cluster: 3-isopropylmalate dehydratase, large
subunit, putative; n=9; cellular organisms|Rep:
3-isopropylmalate dehydratase, large subunit, putative -
Chlorobium tepidum
Length = 431
Score = 37.9 bits (84), Expect = 0.28
Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 1/79 (1%)
Frame = +2
Query: 272 ENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIP-WELKCPKVIGVKLTGK 448
E + PG ++ GTDSHT DA ++ WE K P + G+
Sbjct: 115 EGFNLPGTVLFGTDSHTCTSGAFGMFGSGIGNTDAAFILGTGKLWE-KVPDSMKFTFEGQ 173
Query: 449 LTGWTSPKDVILKVAGILT 505
+ + + KD+IL++ G +T
Sbjct: 174 MPEYLTAKDLILQILGDIT 192
>UniRef50_A7DIC6 Cluster: Metallophosphoesterase; n=2;
Methylobacterium extorquens PA1|Rep:
Metallophosphoesterase - Methylobacterium extorquens PA1
Length = 331
Score = 37.9 bits (84), Expect = 0.28
Identities = 16/35 (45%), Positives = 22/35 (62%)
Frame = +1
Query: 493 RHPDCEGGTGAIVEYHGPGVDHISCTGMATICNMG 597
RH D + I + HG GVDH++CTG +CN+G
Sbjct: 56 RHHDMDLLGALIADLHGQGVDHVACTG--DLCNLG 88
>UniRef50_A0ZF76 Cluster: 3-isopropylmalate dehydratase, LeuC
subunit; n=2; Nostocaceae|Rep: 3-isopropylmalate
dehydratase, LeuC subunit - Nodularia spumigena CCY 9414
Length = 574
Score = 37.9 bits (84), Expect = 0.28
Identities = 20/75 (26%), Positives = 34/75 (45%)
Frame = +2
Query: 272 ENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVKLTGKL 451
+ + PG+++ GTDSHT D ++ A ++ P + +L+G L
Sbjct: 266 KGFVRPGMIIAGTDSHTCTYGALGAFSAGVGTTDMANIYAMGDMWIRVPSTLVFELSGTL 325
Query: 452 TGWTSPKDVILKVAG 496
S KD+IL + G
Sbjct: 326 PPHISAKDIILFILG 340
>UniRef50_Q08N42 Cluster: Aconitate hydratase; n=2;
Cystobacterineae|Rep: Aconitate hydratase - Stigmatella
aurantiaca DW4/3-1
Length = 691
Score = 37.5 bits (83), Expect = 0.37
Identities = 24/91 (26%), Positives = 36/91 (39%)
Frame = +2
Query: 230 FLEARLWYFHQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWEL 409
F +A + H PG +++G DSHT + AD + L
Sbjct: 139 FQDANVTILHTKFYRELVQPGQVVLGADSHTSSHGGLGAFAIGLGGADVTAALVLGQSWL 198
Query: 410 KCPKVIGVKLTGKLTGWTSPKDVILKVAGIL 502
+ P+ I V+ G+ KD+ILK G L
Sbjct: 199 EVPEAIAVEYQGEPPFGIGGKDIILKTLGTL 229
Score = 33.9 bits (74), Expect = 4.6
Identities = 23/74 (31%), Positives = 29/74 (39%)
Frame = +1
Query: 529 VEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLKFEPDAHDIAATANFLQ 708
VEY GP V S TI NM AE G +F + +L D A + Q
Sbjct: 240 VEYRGPAVRGFSTDMRFTIANMTAEFGGLNGIFEADEAAARWLSRRSSDKD---EALYFQ 296
Query: 709 ATCSTARQQRHPMN 750
A RHP++
Sbjct: 297 ADPDAPYVARHPID 310
>UniRef50_A6XPX3 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 319
Score = 37.5 bits (83), Expect = 0.37
Identities = 16/21 (76%), Positives = 18/21 (85%)
Frame = +1
Query: 595 GAEIGATTSVFPYNSRMEAYL 657
GAEIGATTS+FP+N RM YL
Sbjct: 1 GAEIGATTSLFPFNDRMYDYL 21
>UniRef50_A3LRP7 Cluster: 3-isopropylmalate dehydratase; n=1; Pichia
stipitis|Rep: 3-isopropylmalate dehydratase - Pichia
stipitis (Yeast)
Length = 677
Score = 37.5 bits (83), Expect = 0.37
Identities = 16/43 (37%), Positives = 23/43 (53%)
Frame = +1
Query: 529 VEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYL 657
VEY G G+ ++SC I NM E GA VF + + A++
Sbjct: 201 VEYDGQGLQYLSCDARFAISNMSTEFGALAGVFVPDQQTSAFI 243
Score = 33.1 bits (72), Expect = 8.0
Identities = 20/78 (25%), Positives = 32/78 (41%)
Frame = +2
Query: 257 HQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGVK 436
H A PG+L+IG DSHT + +D V + + P+ + ++
Sbjct: 109 HTEFYRERAQPGMLIIGADSHTCSSGALGCLAVGLGTSDVVFPLITGETFFQIPETLKIE 168
Query: 437 LTGKLTGWTSPKDVILKV 490
+ GK KD IL +
Sbjct: 169 IVGKPNFGIGGKDTILHI 186
>UniRef50_Q7N5S3 Cluster: Similar to large subunit of
3-isopropylmalate dehydratase; n=1; Photorhabdus
luminescens subsp. laumondii|Rep: Similar to large
subunit of 3-isopropylmalate dehydratase - Photorhabdus
luminescens subsp. laumondii
Length = 413
Score = 37.1 bits (82), Expect = 0.49
Identities = 24/77 (31%), Positives = 35/77 (45%), Gaps = 1/77 (1%)
Frame = +2
Query: 257 HQIILENYAF-PGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGV 433
H I LE F PG ++IG DSHT +D + M LK P+ + +
Sbjct: 105 HLIALEEQWFQPGNIVIGADSHTCTGGAVQSLALGMGASDVLAAMLTGQTWLKVPETVSL 164
Query: 434 KLTGKLTGWTSPKDVIL 484
++G+ T KDV+L
Sbjct: 165 SISGQPHPATRTKDVML 181
>UniRef50_A6NVP4 Cluster: Putative uncharacterized protein; n=1;
Bacteroides capillosus ATCC 29799|Rep: Putative
uncharacterized protein - Bacteroides capillosus ATCC
29799
Length = 396
Score = 37.1 bits (82), Expect = 0.49
Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 1/82 (1%)
Frame = +2
Query: 257 HQIILENY-AFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGV 433
HQ++ E + A PG L+ DSHT + MA +L+ P+V+ +
Sbjct: 100 HQLMYEKHRANPGDLIAIADSHTGTCGGYGVMGVGVGSTELAAAMATGKLDLEVPQVVQI 159
Query: 434 KLTGKLTGWTSPKDVILKVAGI 499
LTGK KD+IL + +
Sbjct: 160 HLTGKKPANVFGKDLILYLGSV 181
Score = 33.1 bits (72), Expect = 8.0
Identities = 12/31 (38%), Positives = 19/31 (61%)
Frame = +1
Query: 535 YHGPGVDHISCTGMATICNMGAEIGATTSVF 627
+ G G++ S T+CNMG EIG+ ++F
Sbjct: 194 FTGEGIEDFSVAERMTVCNMGIEIGSMITIF 224
>UniRef50_P48200 Cluster: Iron-responsive element-binding protein 2;
n=45; Euteleostomi|Rep: Iron-responsive element-binding
protein 2 - Homo sapiens (Human)
Length = 963
Score = 37.1 bits (82), Expect = 0.49
Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 2/87 (2%)
Frame = +2
Query: 236 EARLWYFHQIILE--NYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWEL 409
+ L Y +++ E + FP + +GTDSH + VM +P L
Sbjct: 254 QINLEYLSRVVFEEKDLLFPDSV-VGTDSHITMVNGLGILGWGVGGIETEAVMLGLPVSL 312
Query: 410 KCPKVIGVKLTGKLTGWTSPKDVILKV 490
P+V+G +LTG + + DV+L +
Sbjct: 313 TLPEVVGCELTGSSNPFVTSIDVVLGI 339
Score = 37.1 bits (82), Expect = 0.49
Identities = 18/43 (41%), Positives = 22/43 (51%)
Frame = +1
Query: 511 GGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNS 639
G G VE+ G GV +S TI NM E GA S FP ++
Sbjct: 347 GVAGKFVEFFGSGVSQLSIVDRTTIANMCPEYGAILSFFPVDN 389
>UniRef50_Q1LAU9 Cluster: Homoaconitate hydratase family protein;
n=8; Burkholderiales|Rep: Homoaconitate hydratase family
protein - Ralstonia metallidurans (strain CH34 / ATCC
43123 / DSM 2839)
Length = 440
Score = 36.7 bits (81), Expect = 0.65
Identities = 34/135 (25%), Positives = 54/135 (40%), Gaps = 5/135 (3%)
Frame = +2
Query: 257 HQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGV 433
H ++ E + PG ++G DSH+P + V+A L+ P I V
Sbjct: 116 HVVLPERGHILPGRFIVGGDSHSPTGGAFGAYMFGIGATEMAGVLATGEIWLRVPNTIRV 175
Query: 434 KLTGKLTGWTSPKDVILKVAGILTVR----EVPAPSWSTTDPGWTTSRVQAWRQSATWAL 601
+ G L+ KD++L + L + EV + ST R+ S
Sbjct: 176 EWQGTLSDGVCAKDIMLFLCATLGMAGGRYEVIEYTGSTVKTLSMQERMTLTNMSTELGA 235
Query: 602 RSALPLACSRTTPAW 646
++AL +A TT AW
Sbjct: 236 QTAL-IAPDATTMAW 249
>UniRef50_O67078 Cluster: 3-isopropylmalate dehydratase large
subunit; n=50; cellular organisms|Rep: 3-isopropylmalate
dehydratase large subunit - Aquifex aeolicus
Length = 432
Score = 36.3 bits (80), Expect = 0.86
Identities = 26/85 (30%), Positives = 34/85 (40%), Gaps = 1/85 (1%)
Frame = +2
Query: 257 HQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGV 433
H I+ E PG L++G DSHT D MA L+ P+ +
Sbjct: 103 HAILPEQGLVVPGDLVVGADSHTCTYGALGAFATGVGSTDIAYAMATGEVWLRVPESMKF 162
Query: 434 KLTGKLTGWTSPKDVILKVAGILTV 508
GKL W KD+IL G + V
Sbjct: 163 IFYGKLKPWVMGKDLILYTIGQIGV 187
>UniRef50_UPI00006D922D Cluster: COG0065: 3-isopropylmalate
dehydratase large subunit; n=1; Pseudomonas aeruginosa
2192|Rep: COG0065: 3-isopropylmalate dehydratase large
subunit - Pseudomonas aeruginosa 2192
Length = 329
Score = 35.9 bits (79), Expect = 1.1
Identities = 15/34 (44%), Positives = 19/34 (55%)
Frame = +1
Query: 511 GGTGAIVEYHGPGVDHISCTGMATICNMGAEIGA 612
GG G +E+ G + +S G TICNM E GA
Sbjct: 201 GGNGHAIEFAGSAIRDLSIEGRMTICNMSIEAGA 234
>UniRef50_Q4WBR0 Cluster: Aconitase family protein; n=7;
Pezizomycotina|Rep: Aconitase family protein -
Aspergillus fumigatus (Sartorya fumigata)
Length = 811
Score = 35.9 bits (79), Expect = 1.1
Identities = 24/79 (30%), Positives = 36/79 (45%), Gaps = 1/79 (1%)
Frame = +2
Query: 257 HQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXAD-AVDVMANIPWELKCPKVIGV 433
H A PG+L+IG+DSHT + AD + ++ W +K P+ I +
Sbjct: 240 HTEFYRERAQPGMLIIGSDSHTCSSGALGCLAIGLGAADVTLPLVTGETW-VKVPESISI 298
Query: 434 KLTGKLTGWTSPKDVILKV 490
+L G KDVIL +
Sbjct: 299 RLVGVPKPGIGGKDVILYI 317
Score = 35.1 bits (77), Expect = 2.0
Identities = 15/34 (44%), Positives = 20/34 (58%)
Frame = +1
Query: 526 IVEYHGPGVDHISCTGMATICNMGAEIGATTSVF 627
IVE+ G GV ++S ICNM AE+ T +F
Sbjct: 331 IVEFSGAGVQYLSADARFAICNMTAELCGITGIF 364
>UniRef50_Q8PUG1 Cluster: 3-isopropylmalate dehydratase large
subunit 2; n=30; Archaea|Rep: 3-isopropylmalate
dehydratase large subunit 2 - Methanosarcina mazei
(Methanosarcina frisia)
Length = 420
Score = 35.5 bits (78), Expect = 1.5
Identities = 25/88 (28%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Frame = +2
Query: 257 HQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGV 433
HQ++ E + PG L++G+DSHT D V A + P+
Sbjct: 103 HQVLPEKGHVKPGDLIVGSDSHTCAYGSLGAFSTGIGSTDMAAVFATGKLWFRVPETFRF 162
Query: 434 KLTGKLTGWTSPKDVILKVAGILTVREV 517
++ GKL KD+IL + G + V V
Sbjct: 163 EVEGKLPERVYSKDLILHLIGDVGVEGV 190
>UniRef50_Q7WPW8 Cluster: Aconitase family protein; n=2;
Bordetella|Rep: Aconitase family protein - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 436
Score = 35.1 bits (77), Expect = 2.0
Identities = 16/47 (34%), Positives = 24/47 (51%)
Frame = +1
Query: 520 GAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLK 660
G +E+ GPGV + + N IGATT +FP + + YL+
Sbjct: 194 GCAIEFDGPGVATMPLDVRMAVANGAPHIGATTMIFPSDDILLDYLR 240
>UniRef50_Q0VKG5 Cluster: Aconitate hydratase; n=2; Bacteria|Rep:
Aconitate hydratase - Pseudomonas fluorescens
Length = 149
Score = 35.1 bits (77), Expect = 2.0
Identities = 18/47 (38%), Positives = 26/47 (55%)
Frame = +1
Query: 520 GAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLK 660
GA +E+ G ++ ATI NM E GAT +F +++ AYLK
Sbjct: 63 GAWLEFFXEGASALTLGDRATISNMAPEYGATAXMFYIDAQTIAYLK 109
>UniRef50_Q05FR0 Cluster: 3-isopropylmalate dehydratase large
subunit; n=1; Candidatus Carsonella ruddii PV|Rep:
3-isopropylmalate dehydratase large subunit - Carsonella
ruddii (strain PV)
Length = 456
Score = 35.1 bits (77), Expect = 2.0
Identities = 14/39 (35%), Positives = 23/39 (58%)
Frame = +1
Query: 508 EGGTGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSV 624
+GGTG +E+ G + +S + T+CNM E G+ S+
Sbjct: 190 KGGTGYSIEFKGDCIKSLSISEKMTLCNMSIEAGSKISI 228
>UniRef50_A1W553 Cluster: Aconitate hydratase 1 precursor; n=8;
Proteobacteria|Rep: Aconitate hydratase 1 precursor -
Acidovorax sp. (strain JS42)
Length = 972
Score = 35.1 bits (77), Expect = 2.0
Identities = 17/47 (36%), Positives = 23/47 (48%)
Frame = +1
Query: 520 GAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYNSRMEAYLK 660
G VE+ G G ++ ATI NM E GAT FP + + Y +
Sbjct: 285 GKFVEFFGEGTRTLALPDRATIGNMAPEYGATMGFFPVDEKTIDYFR 331
>UniRef50_Q6BX71 Cluster: 5-aminolevulinate synthase, mitochondrial
precursor; n=4; cellular organisms|Rep:
5-aminolevulinate synthase, mitochondrial precursor -
Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
Length = 575
Score = 35.1 bits (77), Expect = 2.0
Identities = 16/61 (26%), Positives = 29/61 (47%)
Frame = +3
Query: 9 LRPDRVAMQDATAQMAMLQFISSGLPRVAVPSTIHCDHLIEAQVGGEKDLARAKDLNKEV 188
+R R +QD AQ +++ + L + +P + H++ VG D +A DL +
Sbjct: 408 IRYQRSTLQDRIAQQTNTRYVKNNLTDIGIPVIPNPSHIVPVLVGNALDAKKASDLLLDK 467
Query: 189 Y 191
Y
Sbjct: 468 Y 468
>UniRef50_Q938C9 Cluster: 3-isopropylmalate dehydratase large
subunit; n=4; Mycobacterium|Rep: 3-isopropylmalate
dehydratase large subunit - Mycobacterium smegmatis
(strain ATCC 700084 / mc(2)155)
Length = 422
Score = 34.7 bits (76), Expect = 2.6
Identities = 17/40 (42%), Positives = 21/40 (52%)
Frame = +1
Query: 517 TGAIVEYHGPGVDHISCTGMATICNMGAEIGATTSVFPYN 636
T + +EY GPG+ I TI GAEI A S F Y+
Sbjct: 185 TNSNLEYGGPGLASIPLNDRRTIATQGAEISADFSTFAYD 224
>UniRef50_Q8KSY7 Cluster: Putative cyclase GrhE; n=1; Streptomyces
sp. JP95|Rep: Putative cyclase GrhE - Streptomyces sp.
JP95
Length = 323
Score = 34.3 bits (75), Expect = 3.5
Identities = 21/65 (32%), Positives = 30/65 (46%)
Frame = +2
Query: 449 LTGWTSPKDVILKVAGILTVREVPAPSWSTTDPGWTTSRVQAWRQSATWALRSALPLACS 628
+T W + + + I +EVP PS W + S+ LRSALP + +
Sbjct: 64 VTSWVTRRTLDPAARRIDFRQEVPGPSEPGVTGSWVVEELP--EGSSRLTLRSALPASAT 121
Query: 629 RTTPA 643
RTTPA
Sbjct: 122 RTTPA 126
>UniRef50_Q6L0K5 Cluster: 3-isopropylmalate dehydratase large
subunit; n=2; Thermoplasmatales|Rep: 3-isopropylmalate
dehydratase large subunit - Picrophilus torridus
Length = 413
Score = 33.9 bits (74), Expect = 4.6
Identities = 21/79 (26%), Positives = 34/79 (43%), Gaps = 1/79 (1%)
Frame = +2
Query: 257 HQIILEN-YAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGV 433
HQ+++E +A PG L+ G DSHT +A + K P+ +
Sbjct: 99 HQVMMEKGFAAPGRLIAGADSHTNTYGALSCVSVGIGSTEAGVIFGTGRMWFKVPETDLI 158
Query: 434 KLTGKLTGWTSPKDVILKV 490
++ G+ KD+IL V
Sbjct: 159 RINGRPKKGVYGKDIILNV 177
>UniRef50_A0GFK5 Cluster: RAD55; n=2; Burkholderia|Rep: RAD55 -
Burkholderia phytofirmans PsJN
Length = 531
Score = 33.5 bits (73), Expect = 6.1
Identities = 22/68 (32%), Positives = 31/68 (45%), Gaps = 3/68 (4%)
Frame = -1
Query: 314 SLCRS*VDQGT---HSSPE*SDGNTRAGLPETDSIFSSGSL*KLVYFFVEVLSPGQILLA 144
SL R+ D T H S S N G+P D I G + VY + G+ +L+
Sbjct: 30 SLLRTLNDSSTMTNHESQTSSRSNVETGVPGLDEILGGGLVRGGVYLLEGMAGAGKTILS 89
Query: 143 SDLGFDQV 120
S +GF +V
Sbjct: 90 SQIGFHRV 97
>UniRef50_Q4VDG4 Cluster: Putative 3-isopropylmalate dehydratase
large subunit; n=1; Hyaloperonospora parasitica|Rep:
Putative 3-isopropylmalate dehydratase large subunit -
Hyaloperonospora parasitica
Length = 714
Score = 33.5 bits (73), Expect = 6.1
Identities = 25/91 (27%), Positives = 33/91 (36%)
Frame = +2
Query: 230 FLEARLWYFHQIILENYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWEL 409
F A H A PG ++IG DSHT + D V +
Sbjct: 106 FQPANTTIMHTEFARKRAQPGQIIIGADSHTCSAGGMGAFAAGLGAGDVVMPLVTGQTWF 165
Query: 410 KCPKVIGVKLTGKLTGWTSPKDVILKVAGIL 502
K P+V ++ G KDVIL + G L
Sbjct: 166 KVPEVCYIEFVGAPHFGIGGKDVILHILGEL 196
>UniRef50_Q8U0C0 Cluster: 3-isopropylmalate dehydratase large
subunit 2; n=4; Thermococcaceae|Rep: 3-isopropylmalate
dehydratase large subunit 2 - Pyrococcus furiosus
Length = 380
Score = 33.5 bits (73), Expect = 6.1
Identities = 20/83 (24%), Positives = 35/83 (42%), Gaps = 1/83 (1%)
Frame = +2
Query: 257 HQIILE-NYAFPGLLMIGTDSHTPNXXXXXXXXXXXXXADAVDVMANIPWELKCPKVIGV 433
HQ+++E +++G DSHTP D ++ + P+ +GV
Sbjct: 89 HQLVVEMGLTENSKIVVGADSHTPTLGALGVFAVGMGATDVAVILGLGKTWFRIPESVGV 148
Query: 434 KLTGKLTGWTSPKDVILKVAGIL 502
L G + + DVIL + +L
Sbjct: 149 ILEGNPSRYVMATDVILHLLSLL 171
>UniRef50_Q47LU6 Cluster: Putative uncharacterized protein
precursor; n=1; Thermobifida fusca YX|Rep: Putative
uncharacterized protein precursor - Thermobifida fusca
(strain YX)
Length = 209
Score = 33.1 bits (72), Expect = 8.0
Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 3/86 (3%)
Frame = +2
Query: 389 ANIPWELKCPKVIGVKLTGKLTGWTSPKDVILKVAGILTVREVPAPSWSTTDPGWTTSRV 568
+++P C ++GV L G + T + V+G + + P W+ DPG T +
Sbjct: 38 SSVPLPTACAVLMGVGLLGAVLAATRFSPLAAFVSGGVLLG---GPLWALLDPGSLTQLL 94
Query: 569 QAW---RQSATWALRSALPLACSRTT 637
AW S L LPL C+ T
Sbjct: 95 PAWLVGSDSLVHPLGPGLPLLCTLGT 120
>UniRef50_Q30ZB6 Cluster: DTDP-4-dehydrorhamnose reductase; n=4;
Desulfovibrionaceae|Rep: DTDP-4-dehydrorhamnose
reductase - Desulfovibrio desulfuricans (strain G20)
Length = 294
Score = 33.1 bits (72), Expect = 8.0
Identities = 15/35 (42%), Positives = 20/35 (57%)
Frame = +1
Query: 499 PDCEGGTGAIVEYHGPGVDHISCTGMATICNMGAE 603
PD G+ +VE G G+ H+S G AT C + AE
Sbjct: 193 PDLAAGSRLLVEKGGTGLFHLSNGGQATWCELAAE 227
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 869,530,230
Number of Sequences: 1657284
Number of extensions: 19133876
Number of successful extensions: 58084
Number of sequences better than 10.0: 110
Number of HSP's better than 10.0 without gapping: 54819
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 58037
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 65850543200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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