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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= NV021816X
         (536 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_A7T6B8 Cluster: Predicted protein; n=1; Nematostella ve...   139   4e-32
UniRef50_Q4S0L0 Cluster: Malic enzyme; n=2; Tetraodon nigrovirid...   135   7e-31
UniRef50_Q16798 Cluster: NADP-dependent malic enzyme, mitochondr...   133   3e-30
UniRef50_P23368 Cluster: NAD-dependent malic enzyme, mitochondri...   131   1e-29
UniRef50_Q5BX10 Cluster: Malic enzyme; n=1; Schistosoma japonicu...   130   3e-29
UniRef50_P48163 Cluster: NADP-dependent malic enzyme; n=63; Euka...   130   3e-29
UniRef50_P06801 Cluster: NADP-dependent malic enzyme; n=52; cell...   126   4e-28
UniRef50_A2ZQ54 Cluster: Malic enzyme; n=9; Oryza sativa|Rep: Ma...   124   1e-27
UniRef50_A0L5P5 Cluster: Malate dehydrogenase (Oxaloacetate-deca...   122   7e-27
UniRef50_A7CWP9 Cluster: Malate dehydrogenase (Oxaloacetate-deca...   121   1e-26
UniRef50_Q89G76 Cluster: Malic enzyme; n=3; cellular organisms|R...   119   4e-26
UniRef50_Q0AIF8 Cluster: Malate dehydrogenase (Oxaloacetate-deca...   119   4e-26
UniRef50_P16243 Cluster: NADP-dependent malic enzyme, chloroplas...   115   6e-25
UniRef50_A7PC00 Cluster: Chromosome chr2 scaffold_11, whole geno...   111   7e-24
UniRef50_Q016K2 Cluster: NADP dependent malic enzyme; n=2; Ostre...   107   2e-22
UniRef50_Q8D911 Cluster: NAD-dependent malic enzyme; n=187; cell...   103   3e-21
UniRef50_A6SA55 Cluster: Malic enzyme; n=2; Sclerotiniaceae|Rep:...   101   8e-21
UniRef50_A7IMB8 Cluster: Malate dehydrogenase (Oxaloacetate-deca...   100   4e-20
UniRef50_Q8I8I4 Cluster: Malic enzyme; n=4; Eukaryota|Rep: Malic...   100   4e-20
UniRef50_Q86NT5 Cluster: Malic enzyme; n=2; Drosophila melanogas...    99   6e-20
UniRef50_UPI0000D9F768 Cluster: PREDICTED: similar to Y48B6A.12,...    97   2e-19
UniRef50_A3QW96 Cluster: Malic enzyme; n=10; Tigriopus californi...    97   2e-19
UniRef50_P37221 Cluster: NAD-dependent malic enzyme 62 kDa isofo...    97   2e-19
UniRef50_Q4X1Z2 Cluster: NADP-dependent malic enzyme MaeA; n=11;...    96   5e-19
UniRef50_P78715 Cluster: Malic enzyme, hydrogenosomal precursor;...    95   7e-19
UniRef50_A1ZAF7 Cluster: Malic enzyme; n=5; Sophophora|Rep: Mali...    94   2e-18
UniRef50_Q01AM5 Cluster: NADP+-dependent malic enzyme; n=2; Ostr...    93   3e-18
UniRef50_Q00XN9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma...    91   1e-17
UniRef50_A3BK03 Cluster: Malic enzyme; n=2; Oryza sativa|Rep: Ma...    91   2e-17
UniRef50_Q4PC56 Cluster: Malic enzyme; n=1; Ustilago maydis|Rep:...    90   3e-17
UniRef50_Q875H8 Cluster: Malic enzyme; n=1; Mucor circinelloides...    89   6e-17
UniRef50_Q9HE50 Cluster: Malic enzyme; n=6; Pezizomycotina|Rep: ...    89   8e-17
UniRef50_A0Q531 Cluster: NAD-dependent malic enzyme; n=10; Franc...    86   4e-16
UniRef50_A4RQC9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma...    86   4e-16
UniRef50_Q9RYN4 Cluster: Malate oxidoreductase; n=6; Deinococci|...    85   1e-15
UniRef50_A2EKE3 Cluster: Malic enzyme; n=14; Trichomonadidae|Rep...    84   2e-15
UniRef50_A1SVL3 Cluster: Malic enzyme aka malate dehydrogenase (...    81   2e-14
UniRef50_P45868 Cluster: Probable NAD-dependent malic enzyme 2; ...    79   8e-14
UniRef50_Q7SHJ8 Cluster: Malic enzyme; n=12; Pezizomycotina|Rep:...    77   3e-13
UniRef50_Q4QAQ6 Cluster: Malic enzyme, putative; n=20; Trypanoso...    76   6e-13
UniRef50_Q5K758 Cluster: Malic enzyme; n=1; Filobasidiella neofo...    74   2e-12
UniRef50_A4SKB8 Cluster: NAD-dependent malic enzyme; n=2; Aeromo...    71   2e-11
UniRef50_Q95061 Cluster: Malic enzyme; n=2; Giardia intestinalis...    70   3e-11
UniRef50_A6XP71 Cluster: Malic enzyme protein 2; n=2; Mucoromyco...    70   4e-11
UniRef50_Q6AL43 Cluster: Related to NAD-dependent malic enzyme; ...    69   7e-11
UniRef50_A3YYQ0 Cluster: Malate oxidoreductase; n=1; Synechococc...    69   9e-11
UniRef50_A2QY66 Cluster: Malic enzyme; n=2; cellular organisms|R...    68   2e-10
UniRef50_P40375 Cluster: NAD-dependent malic enzyme; n=3; Schizo...    63   3e-09
UniRef50_Q7K3R0 Cluster: Malic enzyme; n=2; Sophophora|Rep: Mali...    58   2e-07
UniRef50_Q48796 Cluster: Malolactic enzyme; n=49; Bacteria|Rep: ...    58   2e-07
UniRef50_Q2HCG7 Cluster: Malic enzyme; n=1; Chaetomium globosum|...    57   3e-07
UniRef50_Q5CS07 Cluster: Malic enzyme; n=2; Cryptosporidium|Rep:...    56   4e-07
UniRef50_A4RZU1 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma...    56   7e-07
UniRef50_Q8Y5Y8 Cluster: Lmo1915 protein; n=15; Firmicutes|Rep: ...    54   2e-06
UniRef50_Q5KBK5 Cluster: Nad-dependent malic enzyme, putative; n...    52   6e-06
UniRef50_Q5KEY3 Cluster: Malic enzyme; n=1; Filobasidiella neofo...    52   1e-05
UniRef50_P36013 Cluster: NAD-dependent malic enzyme, mitochondri...    51   2e-05
UniRef50_Q9S4T5 Cluster: NAD-malate oxidoreductase homolog; n=15...    48   1e-04
UniRef50_Q8S484 Cluster: Putative NADP-dependent malic enzyme; n...    46   4e-04
UniRef50_UPI0000DB7FF6 Cluster: PREDICTED: hypothetical protein,...    42   0.009
UniRef50_Q4SHK3 Cluster: Chromosome 5 SCAF14581, whole genome sh...    34   2.4  
UniRef50_Q7WLT2 Cluster: Putative uncharacterized protein; n=1; ...    34   2.4  
UniRef50_A1CKF3 Cluster: Stress response protein (Ish1), putativ...    34   2.4  
UniRef50_Q4RNM6 Cluster: Chromosome 21 SCAF15012, whole genome s...    33   3.1  
UniRef50_UPI0001560FE5 Cluster: PREDICTED: similar to KIAA2007 p...    33   4.2  
UniRef50_Q7QQ11 Cluster: GLP_227_10956_9892; n=1; Giardia lambli...    33   4.2  
UniRef50_Q1EI20 Cluster: Putative uncharacterized protein; n=2; ...    33   5.5  
UniRef50_A0WC26 Cluster: Multi-sensor hybrid histidine kinase pr...    33   5.5  
UniRef50_UPI0000F2DA74 Cluster: PREDICTED: hypothetical protein;...    32   7.3  
UniRef50_Q4SBA5 Cluster: Chromosome undetermined SCAF14676, whol...    32   7.3  
UniRef50_Q1MKF6 Cluster: Putative uncharacterized protein; n=1; ...    32   7.3  
UniRef50_Q0RK68 Cluster: Type I polyketide synthase; n=2; Franki...    32   9.6  
UniRef50_A4X664 Cluster: GCN5-related N-acetyltransferase; n=2; ...    32   9.6  
UniRef50_Q4Q8F5 Cluster: Putative uncharacterized protein; n=6; ...    32   9.6  

>UniRef50_A7T6B8 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 365

 Score =  139 bits (336), Expect = 4e-32
 Identities = 58/86 (67%), Positives = 75/86 (87%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431
           +YI LM LL+RNE LF+R + D   E+MPIVYTPTVGLAC+K+G+++RRPRGLFI+IHDK
Sbjct: 71  KYIQLMALLERNESLFFRVLFDYTEELMPIVYTPTVGLACRKYGMIFRRPRGLFISIHDK 130

Query: 432 GHVYDVLKNWPETDVRAIVVTDGERI 509
           GH+ D++ NWP T+V+AIV+TDGERI
Sbjct: 131 GHIRDIVSNWPTTEVKAIVMTDGERI 156



 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 29/57 (50%), Positives = 38/57 (66%)
 Frame = +1

Query: 79  LSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPL 249
           + G D ++   LNKG+AFT+EERQ+LGIHGLLPP V +QE Q +     + R  N L
Sbjct: 13  IRGTDIMRDSHLNKGLAFTLEERQILGIHGLLPPCVISQEIQAQRVYRELQRKPNDL 69


>UniRef50_Q4S0L0 Cluster: Malic enzyme; n=2; Tetraodon
           nigroviridis|Rep: Malic enzyme - Tetraodon nigroviridis
           (Green puffer)
          Length = 694

 Score =  135 bits (326), Expect = 7e-31
 Identities = 57/86 (66%), Positives = 72/86 (83%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431
           +YI LM L DRNE LFYR +  ++ + MPIVYTPTVGLACQ++GL +RRPRGLFITIHD+
Sbjct: 118 KYILLMTLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYGLAFRRPRGLFITIHDR 177

Query: 432 GHVYDVLKNWPETDVRAIVVTDGERI 509
           GH+  +L +WPE D++A+VVTDGERI
Sbjct: 178 GHIATMLNSWPEEDIKAVVVTDGERI 203



 Score = 60.9 bits (141), Expect = 2e-08
 Identities = 31/72 (43%), Positives = 43/72 (59%)
 Frame = +1

Query: 52  SGDGQPTSGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSID 231
           + +G   +   G D  ++P LNKGMAFT+EER  +GIHGLLPP   +Q+ QV     S +
Sbjct: 51  ASEGSVRTKKRGYDITRNPHLNKGMAFTLEERLQMGIHGLLPPCFLSQDVQVLRVMKSYE 110

Query: 232 RYENPLNNTSIL 267
              NPL+   +L
Sbjct: 111 TRSNPLDKYILL 122


>UniRef50_Q16798 Cluster: NADP-dependent malic enzyme, mitochondrial
           precursor; n=15; Bilateria|Rep: NADP-dependent malic
           enzyme, mitochondrial precursor - Homo sapiens (Human)
          Length = 604

 Score =  133 bits (321), Expect = 3e-30
 Identities = 58/86 (67%), Positives = 71/86 (82%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431
           +YI LM L DRNE LFYR +  +V + MPIVYTPTVGLACQ +GL +RRPRGLFITIHDK
Sbjct: 106 KYIILMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDK 165

Query: 432 GHVYDVLKNWPETDVRAIVVTDGERI 509
           GH+  +L +WPE +++A+VVTDGERI
Sbjct: 166 GHLATMLNSWPEDNIKAVVVTDGERI 191



 Score = 55.6 bits (128), Expect = 7e-07
 Identities = 28/61 (45%), Positives = 39/61 (63%)
 Frame = +1

Query: 85  GLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNNTSI 264
           G D  ++P LNKGMAFT+EER  LGIHGL+PP   +Q+ Q+       +R ++ L+   I
Sbjct: 50  GYDVTRNPHLNKGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYII 109

Query: 265 L 267
           L
Sbjct: 110 L 110


>UniRef50_P23368 Cluster: NAD-dependent malic enzyme, mitochondrial
           precursor; n=53; Eumetazoa|Rep: NAD-dependent malic
           enzyme, mitochondrial precursor - Homo sapiens (Human)
          Length = 584

 Score =  131 bits (316), Expect = 1e-29
 Identities = 53/86 (61%), Positives = 72/86 (83%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431
           +YIY+MG+ +RNE LFYR + D++  +MPIVYTPTVGLAC ++G ++RRP+GLFI+I D+
Sbjct: 81  KYIYIMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDR 140

Query: 432 GHVYDVLKNWPETDVRAIVVTDGERI 509
           GHV  ++ NWPE  V+A+VVTDGERI
Sbjct: 141 GHVRSIVDNWPENHVKAVVVTDGERI 166



 Score = 56.0 bits (129), Expect = 5e-07
 Identities = 24/57 (42%), Positives = 38/57 (66%)
 Frame = +1

Query: 103 HPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNNTSILWG 273
           +P  NKGMAFT++ERQ+LG+ GLLPP+++TQ+ Q      ++ +  +PL     + G
Sbjct: 31  NPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMG 87


>UniRef50_Q5BX10 Cluster: Malic enzyme; n=1; Schistosoma
           japonicum|Rep: Malic enzyme - Schistosoma japonicum
           (Blood fluke)
          Length = 216

 Score =  130 bits (313), Expect = 3e-29
 Identities = 55/86 (63%), Positives = 71/86 (82%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431
           +YIYL  L DRNE LFY+ V ++V   MP++YTPTVGLACQ++G+V+RRPRGL+ITIHD+
Sbjct: 110 RYIYLTSLQDRNEALFYKLVIEHVEYCMPLIYTPTVGLACQRYGVVFRRPRGLYITIHDR 169

Query: 432 GHVYDVLKNWPETDVRAIVVTDGERI 509
            H+ ++L NWPE  V+AIV TDGERI
Sbjct: 170 HHIPEILNNWPEPIVKAIVFTDGERI 195



 Score = 60.1 bits (139), Expect = 3e-08
 Identities = 27/43 (62%), Positives = 33/43 (76%)
 Frame = +1

Query: 79  LSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQV 207
           L G+D ++ P  N+G AFT+ ERQLLGIHGLLPP V T E+QV
Sbjct: 52  LLGIDVVRDPRTNRGTAFTVNERQLLGIHGLLPPSVLTLEQQV 94


>UniRef50_P48163 Cluster: NADP-dependent malic enzyme; n=63;
           Eukaryota|Rep: NADP-dependent malic enzyme - Homo
           sapiens (Human)
          Length = 572

 Score =  130 bits (313), Expect = 3e-29
 Identities = 56/86 (65%), Positives = 70/86 (81%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431
           +Y+ LM L DRNE LFYR +  ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD+
Sbjct: 71  RYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDR 130

Query: 432 GHVYDVLKNWPETDVRAIVVTDGERI 509
           GH+  VL  WPE  ++AIVVTDGERI
Sbjct: 131 GHIASVLNAWPEDVIKAIVVTDGERI 156



 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 23/36 (63%), Positives = 28/36 (77%)
 Frame = +1

Query: 100 KHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQV 207
           ++P LNK +AFT+EERQ L IHGLLPP   +QE QV
Sbjct: 20  RNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQV 55


>UniRef50_P06801 Cluster: NADP-dependent malic enzyme; n=52;
           cellular organisms|Rep: NADP-dependent malic enzyme -
           Mus musculus (Mouse)
          Length = 572

 Score =  126 bits (303), Expect = 4e-28
 Identities = 56/86 (65%), Positives = 68/86 (79%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431
           +Y+ LM L DRNE LFY  +  +V + MPIVYTPTVGLACQ++ L +R+PRGLFI+IHDK
Sbjct: 71  RYLLLMDLQDRNEKLFYSVLMSDVEKFMPIVYTPTVGLACQQYSLAFRKPRGLFISIHDK 130

Query: 432 GHVYDVLKNWPETDVRAIVVTDGERI 509
           GH+  VL  WPE  V+AIVVTDGERI
Sbjct: 131 GHIASVLNAWPEDVVKAIVVTDGERI 156



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 23/36 (63%), Positives = 28/36 (77%)
 Frame = +1

Query: 100 KHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQV 207
           + P LNK +AFT+EERQ L IHGLLPP + +QE QV
Sbjct: 20  RDPHLNKDLAFTLEERQQLNIHGLLPPCIISQELQV 55


>UniRef50_A2ZQ54 Cluster: Malic enzyme; n=9; Oryza sativa|Rep: Malic
           enzyme - Oryza sativa subsp. japonica (Rice)
          Length = 613

 Score =  124 bits (300), Expect = 1e-27
 Identities = 50/86 (58%), Positives = 72/86 (83%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431
           +Y+ +M L +RNE LFY+ + DNV E++P+VYTPTVG ACQK+G ++R+P+GL++++ DK
Sbjct: 156 RYMAMMDLQERNERLFYKLLIDNVEELLPVVYTPTVGEACQKYGSIFRQPQGLYVSLKDK 215

Query: 432 GHVYDVLKNWPETDVRAIVVTDGERI 509
           G V DVL+NWPE +++ IVVTDGERI
Sbjct: 216 GKVLDVLRNWPERNIQVIVVTDGERI 241



 Score = 44.0 bits (99), Expect = 0.002
 Identities = 23/56 (41%), Positives = 34/56 (60%)
 Frame = +1

Query: 82  SGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPL 249
           SG   L+ P  NKG+AF+ +ER    + GLLPP V +Q+ QV+    ++ +Y  PL
Sbjct: 99  SGYTLLRDPHHNKGLAFSEKERDAHYLRGLLPPAVVSQDLQVKKIMHNLRQYSVPL 154


>UniRef50_A0L5P5 Cluster: Malate dehydrogenase
           (Oxaloacetate-decarboxylating) (NADP(+)); n=1;
           Magnetococcus sp. MC-1|Rep: Malate dehydrogenase
           (Oxaloacetate-decarboxylating) (NADP(+)) - Magnetococcus
           sp. (strain MC-1)
          Length = 556

 Score =  122 bits (293), Expect = 7e-27
 Identities = 52/86 (60%), Positives = 68/86 (79%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431
           +YI+L GL +RNE LFYR V  N+ EM+PI+YTPTVG ACQ +G ++RRP+G+FI+I+DK
Sbjct: 75  KYIFLTGLQERNETLFYRLVMTNIEEMLPIIYTPTVGKACQTYGHIFRRPQGMFISINDK 134

Query: 432 GHVYDVLKNWPETDVRAIVVTDGERI 509
           G + ++L NW   DVR IVVTDG RI
Sbjct: 135 GRIAELLGNWVHKDVRVIVVTDGSRI 160



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 24/46 (52%), Positives = 31/46 (67%)
 Frame = +1

Query: 70  TSGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQV 207
           T   + L+ L  P +NKG+AFT EER L  + GLLPPRV+T E Q+
Sbjct: 14  TGHANPLEILNDPYMNKGVAFTEEERDLFHLRGLLPPRVQTMEAQL 59


>UniRef50_A7CWP9 Cluster: Malate dehydrogenase
           (Oxaloacetate-decarboxylating) (NADP(+)); n=1;
           Opitutaceae bacterium TAV2|Rep: Malate dehydrogenase
           (Oxaloacetate-decarboxylating) (NADP(+)) - Opitutaceae
           bacterium TAV2
          Length = 561

 Score =  121 bits (291), Expect = 1e-26
 Identities = 70/160 (43%), Positives = 87/160 (54%), Gaps = 5/160 (3%)
 Frame = +3

Query: 45  IGLRGRTAHXXXXXXXXXXXXXXXXGHGFYHRRASALG-----HTRVVTTTSQDARGAG* 209
           +GL  R A                 G  F  R   ALG       RV T   Q+ R    
Sbjct: 11  LGLSARGARASLRGTALLGDSVLNKGTAFSERERDALGLRGLLPPRVFTLEQQEQRALN- 69

Query: 210 TMQALDRQIRKST*QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLV 389
            M      I K    YIYL  L  RNE LFYR + ++  EM+P+VYTPTVG AC ++G  
Sbjct: 70  AMAKKPSAIEK----YIYLTTLQSRNETLFYRLLTNHAEEMIPLVYTPTVGQACLEYGAN 125

Query: 390 YRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERI 509
           +RRPRGLFI+I D+G + ++L++WP TDVR IVVTDGERI
Sbjct: 126 FRRPRGLFISIKDRGRIAEILRHWPITDVRMIVVTDGERI 165


>UniRef50_Q89G76 Cluster: Malic enzyme; n=3; cellular organisms|Rep:
           Malic enzyme - Bradyrhizobium japonicum
          Length = 531

 Score =  119 bits (287), Expect = 4e-26
 Identities = 52/86 (60%), Positives = 68/86 (79%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431
           +Y+ L  L DRNE LF+R V DN+ E+ PI+YTPTVGLACQK+GL+++RPRG+FI+  D+
Sbjct: 56  KYVALNALHDRNEALFFRVVVDNIDEIQPIIYTPTVGLACQKYGLIFQRPRGMFISSRDR 115

Query: 432 GHVYDVLKNWPETDVRAIVVTDGERI 509
           G + ++LKNWP    R IVVTDGERI
Sbjct: 116 GQIAEILKNWP-YPARLIVVTDGERI 140



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 23/38 (60%), Positives = 26/38 (68%)
 Frame = +1

Query: 97  LKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVE 210
           L+ P LNKG AFT  ER  LG+ GLLPP V T E QV+
Sbjct: 4   LRDPLLNKGTAFTEAERAALGLRGLLPPCVLTMETQVD 41


>UniRef50_Q0AIF8 Cluster: Malate dehydrogenase
           (Oxaloacetate-decarboxylating) (NADP(+)); n=2;
           Nitrosomonas|Rep: Malate dehydrogenase
           (Oxaloacetate-decarboxylating) (NADP(+)) - Nitrosomonas
           eutropha (strain C71)
          Length = 536

 Score =  119 bits (287), Expect = 4e-26
 Identities = 51/86 (59%), Positives = 67/86 (77%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431
           +YIYL  LL+RN+ LFYR + D++ E+MP+VYTPTVG AC K   ++R+P+G +IT  D+
Sbjct: 62  KYIYLNDLLERNQQLFYRTLVDHIGEIMPLVYTPTVGEACVKLSHIFRKPQGFYITPEDR 121

Query: 432 GHVYDVLKNWPETDVRAIVVTDGERI 509
           G +   LKNWPETDV+ IVVTDGERI
Sbjct: 122 GEIISRLKNWPETDVQIIVVTDGERI 147



 Score = 33.9 bits (74), Expect = 2.4
 Identities = 20/46 (43%), Positives = 26/46 (56%), Gaps = 3/46 (6%)
 Frame = +1

Query: 79  LSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLP---PRVKTQEEQV 207
           L G   L  P  NK  AFT EER+  G+ GLLP     +K Q+++V
Sbjct: 4   LYGKTLLNDPVQNKSTAFTREEREHYGLQGLLPYGVTDIKKQQQRV 49


>UniRef50_P16243 Cluster: NADP-dependent malic enzyme, chloroplast
           precursor; n=79; Magnoliophyta|Rep: NADP-dependent malic
           enzyme, chloroplast precursor - Zea mays (Maize)
          Length = 636

 Score =  115 bits (277), Expect = 6e-25
 Identities = 48/94 (51%), Positives = 70/94 (74%)
 Frame = +3

Query: 228 RQIRKST*QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRG 407
           RQ +    +YI +M L + +E LFY+ + DNV E++P VYTPTVG ACQK+G ++ RP+G
Sbjct: 145 RQYQTPLQRYIAMMNLQETDERLFYKLLIDNVVELLPFVYTPTVGEACQKYGSIFGRPQG 204

Query: 408 LFITIHDKGHVYDVLKNWPETDVRAIVVTDGERI 509
           L++++ DKG V +VL+NWP  +++ I VTDGERI
Sbjct: 205 LYVSLKDKGKVLEVLRNWPHRNIQVICVTDGERI 238



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 27/60 (45%), Positives = 37/60 (61%)
 Frame = +1

Query: 70  TSGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPL 249
           TS  SG   L+ P  NKG+AFT EER    + GLLPP V +QE Q++    ++ +Y+ PL
Sbjct: 92  TSVASGYTLLRDPHHNKGLAFTEEERDGHYLRGLLPPAVLSQELQIKKFMNTLRQYQTPL 151


>UniRef50_A7PC00 Cluster: Chromosome chr2 scaffold_11, whole genome
           shotgun sequence; n=3; Vitis vinifera|Rep: Chromosome
           chr2 scaffold_11, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 573

 Score =  111 bits (268), Expect = 7e-24
 Identities = 48/94 (51%), Positives = 68/94 (72%)
 Frame = +3

Query: 228 RQIRKST*QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRG 407
           RQ +    +Y+ +M   +RNE LFY+ + DNV E++P+VYTPTVG ACQK+G ++RRP+ 
Sbjct: 245 RQYKVPLQRYMAMMDFQERNERLFYKLLIDNVEELLPVVYTPTVGEACQKYGSIFRRPQS 304

Query: 408 LFITIHDKGHVYDVLKNWPETDVRAIVVTDGERI 509
           L+I     G + +VLKNWPE  ++ IVVT+GERI
Sbjct: 305 LYIIDFFMGKILEVLKNWPERSIQVIVVTNGERI 338



 Score = 43.2 bits (97), Expect = 0.004
 Identities = 23/56 (41%), Positives = 33/56 (58%)
 Frame = +1

Query: 82  SGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPL 249
           SG   L+ P  NKG+AFT +ER    + GLLPP V  Q+ Q +    ++ +Y+ PL
Sbjct: 196 SGYTLLRDPHHNKGLAFTEKERDAHYLRGLLPPAVLNQDLQEKRLMHNLRQYKVPL 251


>UniRef50_Q016K2 Cluster: NADP dependent malic enzyme; n=2;
           Ostreococcus|Rep: NADP dependent malic enzyme -
           Ostreococcus tauri
          Length = 641

 Score =  107 bits (256), Expect = 2e-22
 Identities = 43/94 (45%), Positives = 70/94 (74%)
 Frame = +3

Query: 228 RQIRKST*QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRG 407
           R++     ++ +L  L +RNE LFYR V D++ E++P++  PTV   C++ GL+YR+PRG
Sbjct: 131 RRVTSGVEKHAWLPALYERNERLFYRVVKDHLEELLPVLAEPTVWQVCREAGLMYRQPRG 190

Query: 408 LFITIHDKGHVYDVLKNWPETDVRAIVVTDGERI 509
           L++++ DKG VY +LKNWP  +V+A+V+TDG+R+
Sbjct: 191 LYVSMQDKGSVYRLLKNWPVRNVKAVVLTDGQRV 224



 Score = 43.6 bits (98), Expect = 0.003
 Identities = 21/44 (47%), Positives = 28/44 (63%)
 Frame = +1

Query: 79  LSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVE 210
           +SG++ L+    NKGM+F  +ER  L + GLLPP V  Q  QVE
Sbjct: 81  ISGVELLRSGRYNKGMSFARDERDRLNLRGLLPPAVFDQATQVE 124


>UniRef50_Q8D911 Cluster: NAD-dependent malic enzyme; n=187;
           cellular organisms|Rep: NAD-dependent malic enzyme -
           Vibrio vulnificus
          Length = 562

 Score =  103 bits (246), Expect = 3e-21
 Identities = 45/86 (52%), Positives = 62/86 (72%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431
           ++IYL  + D NE LFYR V +++ EMMPI+YTPTVG AC+ F  +YRR RGLF++  ++
Sbjct: 70  KHIYLRNIQDTNETLFYRLVQNHITEMMPIIYTPTVGAACENFSNIYRRGRGLFVSYANR 129

Query: 432 GHVYDVLKNWPETDVRAIVVTDGERI 509
             + D+L N    +V+ IVVTDGERI
Sbjct: 130 DRIDDILNNASNHNVKVIVVTDGERI 155



 Score = 42.7 bits (96), Expect = 0.005
 Identities = 21/52 (40%), Positives = 30/52 (57%)
 Frame = +1

Query: 97  LKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLN 252
           L  P LNKG AF+ EER    + GLLP   +T +EQVE   +    +E+ ++
Sbjct: 18  LSTPLLNKGSAFSAEERISFNLEGLLPETTETIQEQVERAYMQYKAFESDMD 69


>UniRef50_A6SA55 Cluster: Malic enzyme; n=2; Sclerotiniaceae|Rep:
           Malic enzyme - Botryotinia fuckeliana B05.10
          Length = 685

 Score =  101 bits (243), Expect = 8e-21
 Identities = 40/86 (46%), Positives = 64/86 (74%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431
           +Y+YL  L + N HLFYR V +++ ++ P++YTPTVG AC ++  +Y++P GL+++ HD+
Sbjct: 146 KYMYLSNLRNNNVHLFYRLVQEHLTDITPLIYTPTVGEACLRWSEIYQQPEGLYLSYHDR 205

Query: 432 GHVYDVLKNWPETDVRAIVVTDGERI 509
           G++ +VL NW ++DV   VVTDG RI
Sbjct: 206 GNLEEVLGNWRQSDVEMTVVTDGSRI 231


>UniRef50_A7IMB8 Cluster: Malate dehydrogenase
           (Oxaloacetate-decarboxylating) (NADP(+)); n=2;
           Alphaproteobacteria|Rep: Malate dehydrogenase
           (Oxaloacetate-decarboxylating) (NADP(+)) - Xanthobacter
           sp. (strain Py2)
          Length = 550

 Score = 99.5 bits (237), Expect = 4e-20
 Identities = 44/86 (51%), Positives = 60/86 (69%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431
           QY YLM L  RNE +FY+ V  +    +PI+Y PTV  AC+ FG +YRRPRG++IT H K
Sbjct: 75  QYSYLMDLEARNETVFYKAVMSDPKRFIPILYDPTVADACEAFGNLYRRPRGMYITRHMK 134

Query: 432 GHVYDVLKNWPETDVRAIVVTDGERI 509
           G + +VL+NWP+ D+R + V+ G RI
Sbjct: 135 GRMAEVLRNWPQKDIRFVCVSTGGRI 160



 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 29/67 (43%), Positives = 41/67 (61%)
 Frame = +1

Query: 67  PTSGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENP 246
           P S LSGL+ L  P  NKG A+T ++R+ LG+ GLLP  V+T + QVE     +D  ++ 
Sbjct: 13  PKSNLSGLNLLHDPVRNKGTAYTRDDRRQLGLEGLLPHAVETLDRQVERVLDHLDHVKDE 72

Query: 247 LNNTSIL 267
           L+  S L
Sbjct: 73  LDQYSYL 79


>UniRef50_Q8I8I4 Cluster: Malic enzyme; n=4; Eukaryota|Rep: Malic
           enzyme - Mastigamoeba balamuthi (Phreatamoeba balamuthi)
          Length = 568

 Score = 99.5 bits (237), Expect = 4e-20
 Identities = 46/86 (53%), Positives = 59/86 (68%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431
           +Y+YL  L  RN+ LF+  V  +V E +P+VYTPTVG  C KF   +R P GL+IT  DK
Sbjct: 91  KYLYLSQLSQRNQTLFFYLVQHHVEECVPLVYTPTVGEGCTKFSAEFRNPTGLYITPEDK 150

Query: 432 GHVYDVLKNWPETDVRAIVVTDGERI 509
           GHV ++L+NWP  +V  IVVTDG RI
Sbjct: 151 GHVAEILENWPH-EVEIIVVTDGGRI 175



 Score = 36.3 bits (80), Expect = 0.45
 Identities = 24/62 (38%), Positives = 29/62 (46%)
 Frame = +1

Query: 64  QPTSGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYEN 243
           +P  GL+G   L       G AFT EER+ L I GLLP  V+T E Q       +     
Sbjct: 30  RPADGLAGPSWLTLAPT--GTAFTTEERKALRIRGLLPHAVETIEAQAARAYAQLTSQPT 87

Query: 244 PL 249
           PL
Sbjct: 88  PL 89


>UniRef50_Q86NT5 Cluster: Malic enzyme; n=2; Drosophila
           melanogaster|Rep: Malic enzyme - Drosophila melanogaster
           (Fruit fly)
          Length = 610

 Score = 99.1 bits (236), Expect = 6e-20
 Identities = 44/87 (50%), Positives = 61/87 (70%), Gaps = 1/87 (1%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431
           +Y YL  L    E L+++FV+ NV  ++PI+YTPTVGLAC  +G++YR   G+ IT HD+
Sbjct: 102 RYRYLRALRQGYERLYFQFVSKNVHAVLPIIYTPTVGLACTVYGMLYRGMTGIHITKHDR 161

Query: 432 GHVYDVLKNWP-ETDVRAIVVTDGERI 509
           GH+  +L NWP    V+AI VTDG+RI
Sbjct: 162 GHMKQILSNWPMRRSVKAICVTDGQRI 188



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 20/43 (46%), Positives = 30/43 (69%)
 Frame = +1

Query: 115 NKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYEN 243
           NK +AFT+EERQ L IHGL+P  V+T +EQ+   + +   +E+
Sbjct: 56  NKALAFTLEERQRLCIHGLMPACVRTYDEQMLAIESNFHSFES 98


>UniRef50_UPI0000D9F768 Cluster: PREDICTED: similar to Y48B6A.12,
           partial; n=1; Macaca mulatta|Rep: PREDICTED: similar to
           Y48B6A.12, partial - Macaca mulatta
          Length = 456

 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 45/86 (52%), Positives = 60/86 (69%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431
           +YIYL  L DRNE L+++ + D+VAEMMPIVYTP VG ACQ FG ++R  RGL+  + +K
Sbjct: 63  KYIYLESLHDRNETLYFKLLVDHVAEMMPIVYTPVVGKACQLFGHIFRNARGLYFNLSEK 122

Query: 432 GHVYDVLKNWPETDVRAIVVTDGERI 509
           G+  +++ N    D   IVVTDG RI
Sbjct: 123 GNFKEMVWNSNVRDADIIVVTDGSRI 148


>UniRef50_A3QW96 Cluster: Malic enzyme; n=10; Tigriopus
           californicus|Rep: Malic enzyme - Tigriopus californicus
           (Marine copepod)
          Length = 322

 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 41/82 (50%), Positives = 56/82 (68%)
 Frame = +3

Query: 264 LMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVY 443
           L  + DRNE LFYR + DN  +M PI+YTPTVG AC  F  +YRRPRG++ +  D+G + 
Sbjct: 124 LQSVQDRNETLFYRILMDNFQDMAPIIYTPTVGWACSHFSQLYRRPRGMYFSHGDRGEMA 183

Query: 444 DVLKNWPETDVRAIVVTDGERI 509
            ++ NW   +V A+V+TDG RI
Sbjct: 184 SMVYNWESDEVDAVVITDGSRI 205



 Score = 39.9 bits (89), Expect = 0.036
 Identities = 17/40 (42%), Positives = 26/40 (65%)
 Frame = +1

Query: 85  GLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQ 204
           G + +  P  NKG+AF + ER  L + GL+PPR+ + +EQ
Sbjct: 45  GRNLVSDPISNKGLAFPLSERDRLSVRGLVPPRILSIQEQ 84


>UniRef50_P37221 Cluster: NAD-dependent malic enzyme 62 kDa isoform,
           mitochondrial precursor; n=41; Eukaryota|Rep:
           NAD-dependent malic enzyme 62 kDa isoform, mitochondrial
           precursor - Solanum tuberosum (Potato)
          Length = 626

 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 41/79 (51%), Positives = 56/79 (70%)
 Frame = +3

Query: 273 LLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVL 452
           L DRNE L+Y+ + +N+ E  PIVYTPTVGL CQK+  ++RRPRG++ +  D+G +  ++
Sbjct: 122 LHDRNETLYYKVLMENIEEYAPIVYTPTVGLVCQKYSGLFRRPRGMYFSAEDRGEMMSMV 181

Query: 453 KNWPETDVRAIVVTDGERI 509
            NWP   V  IVVTDG RI
Sbjct: 182 YNWPADQVDMIVVTDGSRI 200



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 23/51 (45%), Positives = 28/51 (54%)
 Frame = +1

Query: 88  LDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYE 240
           LD L  P  NKG AF+  ER  L I GLLPP V + E+Q+      + R E
Sbjct: 50  LDILHDPWFNKGTAFSFTERDRLHIRGLLPPNVMSFEQQIARFMADLKRLE 100


>UniRef50_Q4X1Z2 Cluster: NADP-dependent malic enzyme MaeA; n=11;
           Pezizomycotina|Rep: NADP-dependent malic enzyme MaeA -
           Aspergillus fumigatus (Sartorya fumigata)
          Length = 661

 Score = 95.9 bits (228), Expect = 5e-19
 Identities = 37/86 (43%), Positives = 60/86 (69%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431
           +++YL  L   N HLFYR V D++ E+ P++YTP VG ACQK+  +Y++P G++++  D+
Sbjct: 138 KFLYLSTLRKNNVHLFYRLVTDHLKELTPLIYTPVVGEACQKWSEIYQQPEGMYLSWEDR 197

Query: 432 GHVYDVLKNWPETDVRAIVVTDGERI 509
           G++  V+ NWP+ +V    +TDG RI
Sbjct: 198 GNLAAVIANWPQPNVEITCITDGSRI 223


>UniRef50_P78715 Cluster: Malic enzyme, hydrogenosomal precursor;
           n=1; Neocallimastix frontalis|Rep: Malic enzyme,
           hydrogenosomal precursor - Neocallimastix frontalis
           (Rumen fungus)
          Length = 592

 Score = 95.5 bits (227), Expect = 7e-19
 Identities = 41/86 (47%), Positives = 58/86 (67%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431
           ++IYL  L +RNE L+Y+ + +N  E+ PI+YTP VG ACQKF  ++ + RG++ +  D+
Sbjct: 103 KFIYLNHLQNRNETLYYKMILENFVELAPIIYTPVVGEACQKFHKIFTQTRGMYFSTADR 162

Query: 432 GHVYDVLKNWPETDVRAIVVTDGERI 509
           G +  V  NWP  DV  IVVTDG RI
Sbjct: 163 GQMSAVAANWPYDDVDVIVVTDGSRI 188



 Score = 63.3 bits (147), Expect = 3e-09
 Identities = 28/56 (50%), Positives = 39/56 (69%)
 Frame = +1

Query: 82  SGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPL 249
           +GLD L  P LNKG AFT +E+  LGI GL+PPR ++ E Q + CK ++D+  +PL
Sbjct: 46  TGLDILNDPKLNKGSAFTADEKDRLGIRGLVPPRPQSLEAQYKRCKTNLDKISDPL 101


>UniRef50_A1ZAF7 Cluster: Malic enzyme; n=5; Sophophora|Rep: Malic
           enzyme - Drosophila melanogaster (Fruit fly)
          Length = 603

 Score = 94.3 bits (224), Expect = 2e-18
 Identities = 39/86 (45%), Positives = 60/86 (69%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431
           ++ YL  +  R+  L+YRF+ +N+ + +PIVYTPTVG     +GL +++   LFI+IHDK
Sbjct: 94  RFTYLSAVHHRHRRLYYRFIKENIEKSLPIVYTPTVGDVVATYGLNFQQAISLFISIHDK 153

Query: 432 GHVYDVLKNWPETDVRAIVVTDGERI 509
           GH+ D++ NW +  V+AI VTDG R+
Sbjct: 154 GHIRDLMHNWVDEGVKAICVTDGGRV 179



 Score = 42.7 bits (96), Expect = 0.005
 Identities = 18/31 (58%), Positives = 26/31 (83%)
 Frame = +1

Query: 115 NKGMAFTIEERQLLGIHGLLPPRVKTQEEQV 207
           NKG+AFTI+ERQ LGI GL+P  V++ ++Q+
Sbjct: 48  NKGLAFTIKERQRLGIMGLMPCSVRSMDDQM 78


>UniRef50_Q01AM5 Cluster: NADP+-dependent malic enzyme; n=2;
           Ostreococcus|Rep: NADP+-dependent malic enzyme -
           Ostreococcus tauri
          Length = 580

 Score = 93.5 bits (222), Expect = 3e-18
 Identities = 40/86 (46%), Positives = 59/86 (68%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431
           +Y  L+ L   +E  FYR +      ++PI+YTPTVG AC KFG + +RP GL+++ +D 
Sbjct: 102 KYKQLVALQMTDESTFYRMLRSQTETLLPILYTPTVGEACVKFGTLVQRPMGLWVSSNDA 161

Query: 432 GHVYDVLKNWPETDVRAIVVTDGERI 509
           G+V  +++NWP TDV+  V+TDGERI
Sbjct: 162 GNVKQLIRNWPATDVKIAVITDGERI 187


>UniRef50_Q00XN9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
           enzyme - Ostreococcus tauri
          Length = 639

 Score = 91.5 bits (217), Expect = 1e-17
 Identities = 45/98 (45%), Positives = 64/98 (65%)
 Frame = +3

Query: 216 QALDRQIRKST*QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYR 395
           Q+L+R + K    + +L  L DRNE LFYR V D++ E+ PI+YTPTVG AC  F  + R
Sbjct: 129 QSLERPLDK----WQHLQDLKDRNETLFYRLVHDHIEELAPIIYTPTVGDACLNFSKLLR 184

Query: 396 RPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERI 509
           R RG++ ++ D+G +  ++ NW +  V  IVVTDG RI
Sbjct: 185 RARGMYFSVDDRGDINSMMFNW-KRSVSVIVVTDGSRI 221



 Score = 42.3 bits (95), Expect = 0.007
 Identities = 21/56 (37%), Positives = 30/56 (53%)
 Frame = +1

Query: 85  GLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLN 252
           G++ L +P  NKG +FT  ER+ LG+ GL+PPR     +Q           E PL+
Sbjct: 81  GIEVLHNPVYNKGTSFTASERERLGVRGLVPPRFFPIGQQATKIWAQNQSLERPLD 136


>UniRef50_A3BK03 Cluster: Malic enzyme; n=2; Oryza sativa|Rep: Malic
           enzyme - Oryza sativa subsp. japonica (Rice)
          Length = 635

 Score = 90.6 bits (215), Expect = 2e-17
 Identities = 40/81 (49%), Positives = 55/81 (67%), Gaps = 2/81 (2%)
 Frame = +3

Query: 273 LLDRNEHLFYR--FVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYD 446
           L DRNE ++Y+   + DN+ E  PIVYTPTVGL CQ +  ++RRPRG++ +  D+G +  
Sbjct: 154 LHDRNETMYYKAEVLIDNIEEHAPIVYTPTVGLVCQNYSGLFRRPRGMYFSAEDRGEMMS 213

Query: 447 VLKNWPETDVRAIVVTDGERI 509
           ++ NWP   V  IVVTDG RI
Sbjct: 214 MVYNWPADQVDMIVVTDGSRI 234



 Score = 44.0 bits (99), Expect = 0.002
 Identities = 18/42 (42%), Positives = 27/42 (64%)
 Frame = +1

Query: 85  GLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVE 210
           G D L  P  N+G  F++ ER  LG+ GLLPP V + ++Q++
Sbjct: 45  GSDILHDPWFNRGTGFSMTERDRLGLRGLLPPNVVSSQQQID 86


>UniRef50_Q4PC56 Cluster: Malic enzyme; n=1; Ustilago maydis|Rep:
           Malic enzyme - Ustilago maydis (Smut fungus)
          Length = 634

 Score = 89.8 bits (213), Expect = 3e-17
 Identities = 48/132 (36%), Positives = 72/132 (54%), Gaps = 4/132 (3%)
 Frame = +3

Query: 126 GFYHRRASALGHTRVVTTTSQDARGAG*TMQALDRQIRKST*--QYIYLMGLLDRNEHLF 299
           GF + +   LG   ++    Q        ++ L +   KST   +++ L  L   N  L+
Sbjct: 91  GFSYEKRDQLGLRGLLPPAKQSLNTQ--VLRVLHQLRSKSTPLEKHVMLASLRQTNTRLY 148

Query: 300 YRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNW--PETD 473
           Y  +  N  E++P++YTPTVG ACQKF  +YRRP GL I++ DKG +  +++NW  P   
Sbjct: 149 YATILANKEEILPLIYTPTVGEACQKFSHIYRRPEGLSISLEDKGKIASIVENWPVPAGS 208

Query: 474 VRAIVVTDGERI 509
            R  V+TDG RI
Sbjct: 209 PRIAVITDGSRI 220


>UniRef50_Q875H8 Cluster: Malic enzyme; n=1; Mucor
           circinelloides|Rep: Malic enzyme - Mucor circinelloides
          Length = 617

 Score = 89.0 bits (211), Expect = 6e-17
 Identities = 37/86 (43%), Positives = 58/86 (67%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431
           ++++L  L DRNE L+Y+ + +++ E+  I+YTPTVGLA Q    +YRR RG++ +  D+
Sbjct: 106 KFVFLAALHDRNETLYYKIIMEHLEELAGIIYTPTVGLASQMSHSIYRRSRGMYFSSQDR 165

Query: 432 GHVYDVLKNWPETDVRAIVVTDGERI 509
           G +  ++ NWP   V  IVVTDG R+
Sbjct: 166 GQMSAMVYNWPHDKVDVIVVTDGSRV 191



 Score = 50.0 bits (114), Expect = 3e-05
 Identities = 24/55 (43%), Positives = 36/55 (65%)
 Frame = +1

Query: 85  GLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPL 249
           G++ L  P L+KG AF+I ER+ L I GL+PPR +  ++Q+   K ++D  E PL
Sbjct: 50  GVNLLHDPLLSKGTAFSIAERERLSIRGLVPPRCQEMDKQLLRIKRNLDACETPL 104


>UniRef50_Q9HE50 Cluster: Malic enzyme; n=6; Pezizomycotina|Rep:
           Malic enzyme - Neurospora crassa
          Length = 1023

 Score = 88.6 bits (210), Expect = 8e-17
 Identities = 37/86 (43%), Positives = 54/86 (62%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431
           +Y+YL  +  +N  LFYR + D+  EMMP+VYTPT+G  C ++  +Y RP  L+I+I  +
Sbjct: 528 RYLYLSTIKSQNVDLFYRLLMDHAKEMMPLVYTPTIGDVCLQYSTLYTRPEALYISIKQR 587

Query: 432 GHVYDVLKNWPETDVRAIVVTDGERI 509
             +  +L+NWP       VVTDG RI
Sbjct: 588 KSIRTILRNWPYPQPEICVVTDGSRI 613


>UniRef50_A0Q531 Cluster: NAD-dependent malic enzyme; n=10;
           Francisella tularensis|Rep: NAD-dependent malic enzyme -
           Francisella tularensis subsp. novicida (strain U112)
          Length = 604

 Score = 86.2 bits (204), Expect = 4e-16
 Identities = 38/86 (44%), Positives = 57/86 (66%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431
           +Y++L  L D N  LFY FV +N+ E+MPI+YTPTVG A QK+   +R+  GLFI+I  K
Sbjct: 83  KYVFLNRLHDLNTTLFYHFVRENLEEIMPIIYTPTVGEAVQKYSSSFRKQSGLFISISHK 142

Query: 432 GHVYDVLKNWPETDVRAIVVTDGERI 509
            H+  +L+ +    +  ++VTDGE +
Sbjct: 143 KHIARILERYEYNSIDLVLVTDGEAV 168



 Score = 36.7 bits (81), Expect = 0.34
 Identities = 21/59 (35%), Positives = 32/59 (54%)
 Frame = +1

Query: 73  SGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPL 249
           + L+G   L +  LNK +AF+ EER    + G LP +V++ EEQ    +  +D   N L
Sbjct: 23  TNLTGRQLLNNRVLNKDVAFSQEERIAFDLIGYLPEKVESLEEQAIRVRRQLDLKPNSL 81


>UniRef50_A4RQC9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
           enzyme - Ostreococcus lucimarinus CCE9901
          Length = 549

 Score = 86.2 bits (204), Expect = 4e-16
 Identities = 39/86 (45%), Positives = 56/86 (65%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431
           +YI+L  L  +NE LFYR + +++ ++MPIVYTPTVG AC  F  +YR   G++ +  D 
Sbjct: 65  RYIFLENLHMQNERLFYRVLVEHLEDLMPIVYTPTVGEACINFDALYRNRCGMYFSRLDS 124

Query: 432 GHVYDVLKNWPETDVRAIVVTDGERI 509
           G +  +L NWP  +   IVVTDG R+
Sbjct: 125 GVMRRMLDNWPSPETEIIVVTDGGRV 150



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 21/52 (40%), Positives = 30/52 (57%)
 Frame = +1

Query: 97  LKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLN 252
           L  P LNKG  FT  +R+ LG+ GLLP + +T E QV+     +  +E  +N
Sbjct: 13  LDSPSLNKGTGFTFTQRERLGLRGLLPRKYETVEIQVKRAWTQLCAFEEDMN 64


>UniRef50_Q9RYN4 Cluster: Malate oxidoreductase; n=6;
           Deinococci|Rep: Malate oxidoreductase - Deinococcus
           radiodurans
          Length = 580

 Score = 85.0 bits (201), Expect = 1e-15
 Identities = 42/86 (48%), Positives = 53/86 (61%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431
           +++YL  L DRNE LFY  ++ +V EM+PIVYTPTVG A +KF  +YR PRGL ++    
Sbjct: 93  KHVYLRNLQDRNEVLFYALLSHHVEEMLPIVYTPTVGDAVKKFSQIYRYPRGLTLSTRTI 152

Query: 432 GHVYDVLKNWPETDVRAIVVTDGERI 509
                 L N P  DVR IV TD   I
Sbjct: 153 ERAEQALANVPLNDVRIIVATDSSAI 178



 Score = 40.7 bits (91), Expect = 0.021
 Identities = 20/42 (47%), Positives = 27/42 (64%)
 Frame = +1

Query: 85  GLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVE 210
           G +  + P LNKG AFT EER+  G+ GLL P+V + E  +E
Sbjct: 37  GFNLTRIPLLNKGTAFTAEEREAHGLDGLLAPQVDSLEVLIE 78


>UniRef50_A2EKE3 Cluster: Malic enzyme; n=14; Trichomonadidae|Rep:
           Malic enzyme - Trichomonas vaginalis G3
          Length = 567

 Score = 84.2 bits (199), Expect = 2e-15
 Identities = 40/87 (45%), Positives = 57/87 (65%), Gaps = 1/87 (1%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAE-MMPIVYTPTVGLACQKFGLVYRRPRGLFITIHD 428
           +YI+L    ++N   F+RF+  +  E  MPI+YTPTVG ACQK+    +  RG++IT  D
Sbjct: 80  KYIFLANEREKNSQSFWRFLFTHPPEETMPILYTPTVGEACQKWATHRQSYRGIYITPED 139

Query: 429 KGHVYDVLKNWPETDVRAIVVTDGERI 509
            G + D+L+N+P  D+R IVVTD  RI
Sbjct: 140 SGKIKDILRNYPRQDIRCIVVTDAGRI 166



 Score = 43.2 bits (97), Expect = 0.004
 Identities = 22/56 (39%), Positives = 31/56 (55%)
 Frame = +1

Query: 82  SGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPL 249
           +G+  L+   LNKG AFT EER    + GLLP +V T++EQ    +   +    PL
Sbjct: 23  TGMTLLQDGDLNKGTAFTKEERDRFNLRGLLPYKVFTKDEQAARIRRQFELMPTPL 78


>UniRef50_A1SVL3 Cluster: Malic enzyme aka malate dehydrogenase
           (Oxaloacetate-decarboxylating) (NADP(+)); n=4;
           Gammaproteobacteria|Rep: Malic enzyme aka malate
           dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)) -
           Psychromonas ingrahamii (strain 37)
          Length = 571

 Score = 81.0 bits (191), Expect = 2e-14
 Identities = 38/86 (44%), Positives = 55/86 (63%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431
           +Y YL  L DRNE LFY  ++ N+ EM PI+YTPTVG ACQ+F   ++  RGL++T  + 
Sbjct: 80  KYQYLRALQDRNETLFYALISRNIEEMTPIIYTPTVGKACQEFSHRFQIARGLYLTTDNI 139

Query: 432 GHVYDVLKNWPETDVRAIVVTDGERI 509
             V  + + +   D++ IVVTD + I
Sbjct: 140 HDVGSMAREFTGKDIQIIVVTDSQGI 165



 Score = 45.6 bits (103), Expect = 7e-04
 Identities = 23/49 (46%), Positives = 35/49 (71%)
 Frame = +1

Query: 64  QPTSGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVE 210
           +P S L+G + L +  LNK  AFT +ER+   ++GLLPPRV+T E+Q++
Sbjct: 18  RPVS-LTGNELLNNRTLNKSTAFTYQEREDFDLNGLLPPRVQTFEDQLK 65


>UniRef50_P45868 Cluster: Probable NAD-dependent malic enzyme 2;
           n=37; Bacteria|Rep: Probable NAD-dependent malic enzyme
           2 - Bacillus subtilis
          Length = 582

 Score = 78.6 bits (185), Expect = 8e-14
 Identities = 45/121 (37%), Positives = 69/121 (57%), Gaps = 2/121 (1%)
 Frame = +3

Query: 171 VTTTSQDARGAG*TMQALDRQIRKST*QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYT 350
           V +  Q A+ A    QA   ++R    Q +YL  L +RNE LFY+ + +++ EM+P+VYT
Sbjct: 68  VLSLDQQAQRAYEQFQAQPDRLR----QNVYLSDLANRNEVLFYKLLKNHLREMLPVVYT 123

Query: 351 PTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPET--DVRAIVVTDGERIWVWAT 524
           PTVG A Q++   YRRP+G++++I +   +    +N   T  D+  IV TD E I     
Sbjct: 124 PTVGEAIQEYSHEYRRPQGIYLSIDNIDGIEKAFENLHATAGDIDLIVATDSESILGIGD 183

Query: 525 W 527
           W
Sbjct: 184 W 184



 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 24/51 (47%), Positives = 35/51 (68%)
 Frame = +1

Query: 58  DGQPTSGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVE 210
           +G   + L G + L  P LNKG+AF++EERQ LG+ GLLPP V + ++Q +
Sbjct: 26  EGHLETTLRGKEVLSIPTLNKGVAFSLEERQELGLEGLLPPTVLSLDQQAQ 76


>UniRef50_Q7SHJ8 Cluster: Malic enzyme; n=12; Pezizomycotina|Rep:
           Malic enzyme - Neurospora crassa
          Length = 611

 Score = 76.6 bits (180), Expect = 3e-13
 Identities = 43/111 (38%), Positives = 67/111 (60%), Gaps = 12/111 (10%)
 Frame = +3

Query: 213 MQALDRQIRKST*QYI----------YLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVG 362
           +Q+L++Q++++  QY           ++  + ++NE LFYR + D++ EM  +VYTPT G
Sbjct: 68  IQSLEQQVQRAYEQYCSQPNDLAKNTFMTSMKEQNEVLFYRLLHDHLDEMFSVVYTPTEG 127

Query: 363 LACQKFGLVYRRPRGLFITIHDKGHVYDVLKNW--PETDVRAIVVTDGERI 509
            A Q +  ++RRP G+F+ I+D   V   L  W  PE D+  IVVTDGE I
Sbjct: 128 EAIQNYSRLFRRPEGVFLNINDMDSVKRDLAQWGKPE-DIDYIVVTDGEEI 177



 Score = 52.8 bits (121), Expect = 5e-06
 Identities = 25/53 (47%), Positives = 33/53 (62%)
 Frame = +1

Query: 52  SGDGQPTSGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVE 210
           S  G     L G   L HP  NKG AFT EER+   +HGLLPP++++ E+QV+
Sbjct: 24  STSGPLECALKGTVLLNHPYFNKGSAFTKEERRDFALHGLLPPQIQSLEQQVQ 76


>UniRef50_Q4QAQ6 Cluster: Malic enzyme, putative; n=20;
           Trypanosomatidae|Rep: Malic enzyme, putative -
           Leishmania major
          Length = 573

 Score = 75.8 bits (178), Expect = 6e-13
 Identities = 33/86 (38%), Positives = 56/86 (65%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431
           +Y  L  + + N  L+Y  +   + + +PIVYTPTVG ACQ++G +Y++  GL++ +  K
Sbjct: 75  RYQLLRNVQNTNVTLYYAILTRYLKQTLPIVYTPTVGEACQRYGDLYQKDHGLYLDVASK 134

Query: 432 GHVYDVLKNWPETDVRAIVVTDGERI 509
           G V  +++N  +T++  IV+TDG RI
Sbjct: 135 GKVRRLIQNLRKTNIDVIVITDGSRI 160



 Score = 56.0 bits (129), Expect = 5e-07
 Identities = 25/61 (40%), Positives = 39/61 (63%)
 Frame = +1

Query: 85  GLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNNTSI 264
           G+D+L++   NKG AFT  ER  + + GLLPP V+T ++QVE     ++R+  P+N   +
Sbjct: 19  GVDYLRNRFTNKGTAFTAAERSHMNVEGLLPPSVETLDDQVERYWDQLNRFNEPINRYQL 78

Query: 265 L 267
           L
Sbjct: 79  L 79


>UniRef50_Q5K758 Cluster: Malic enzyme; n=1; Filobasidiella
           neoformans|Rep: Malic enzyme - Cryptococcus neoformans
           (Filobasidiella neoformans)
          Length = 600

 Score = 74.1 bits (174), Expect = 2e-12
 Identities = 34/89 (38%), Positives = 55/89 (61%), Gaps = 3/89 (3%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431
           ++++L  +   + +LF+  + D + E+ PIVYTPTVG ACQK+  +Y  P GL++ I DK
Sbjct: 107 KHVHLSKIRREDPNLFFSVMRDELTELAPIVYTPTVGEACQKYSQIYSGPEGLYLNIEDK 166

Query: 432 GHVYDVLKNWPETDV---RAIVVTDGERI 509
             + ++L  +    V   + +VVTDG RI
Sbjct: 167 DRIPEILHQYASKLVAPPQILVVTDGSRI 195


>UniRef50_A4SKB8 Cluster: NAD-dependent malic enzyme; n=2;
           Aeromonas|Rep: NAD-dependent malic enzyme - Aeromonas
           salmonicida (strain A449)
          Length = 516

 Score = 70.5 bits (165), Expect = 2e-11
 Identities = 34/86 (39%), Positives = 54/86 (62%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431
           Q++ L  L + N  LFY  V  ++ E++PI+YTP VG ACQ+   +Y R  GL+++ HD+
Sbjct: 51  QHLLLRQLQEDNPVLFYDLVRHHLPELLPIIYTPVVGEACQRHSDLYLRSHGLYLSWHDR 110

Query: 432 GHVYDVLKNWPETDVRAIVVTDGERI 509
             + D +    E +V  IV++DGER+
Sbjct: 111 DDL-DAIFAAVEQEVDVIVISDGERV 135


>UniRef50_Q95061 Cluster: Malic enzyme; n=2; Giardia
           intestinalis|Rep: Malic enzyme - Giardia lamblia
           (Giardia intestinalis)
          Length = 557

 Score = 70.1 bits (164), Expect = 3e-11
 Identities = 37/89 (41%), Positives = 52/89 (58%), Gaps = 1/89 (1%)
 Frame = +3

Query: 246 T*QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYR-RPRGLFITI 422
           T +++YL  L + NE LF  F    + E++PIVYTPTVG AC  + L+++  PRG ++  
Sbjct: 59  TEKWLYLTRLQEVNETLFSGFCLKYLKEVLPIVYTPTVGTACSNYSLLWQGYPRGFYLNR 118

Query: 423 HDKGHVYDVLKNWPETDVRAIVVTDGERI 509
              G V  +   WP +  R IV TDG RI
Sbjct: 119 THLGKVKQIFDQWPYSP-RIIVATDGTRI 146



 Score = 37.9 bits (84), Expect = 0.15
 Identities = 19/50 (38%), Positives = 26/50 (52%)
 Frame = +1

Query: 97  LKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENP 246
           L++   NK  AFT  ER+   I   LP RV+T E+Q+  C+   D    P
Sbjct: 9   LRNKDCNKDTAFTAAEREAHHIVARLPARVETIEQQISRCRAQFDVLTTP 58


>UniRef50_A6XP71 Cluster: Malic enzyme protein 2; n=2;
           Mucoromycotina|Rep: Malic enzyme protein 2 - Mortierella
           alpina (Mortierella renispora)
          Length = 669

 Score = 69.7 bits (163), Expect = 4e-11
 Identities = 35/98 (35%), Positives = 57/98 (58%), Gaps = 12/98 (12%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVY------RRPRGLF 413
           +Y++L  L + N  LFY  V D + E +P++YTPTVG ACQ +  +Y       +P GLF
Sbjct: 153 KYVFLAWLRNTNVRLFYGLVGDQLEETLPLIYTPTVGTACQNYSSIYPFLAPPGQPDGLF 212

Query: 414 ITIHDKGHVYDVLKNW------PETDVRAIVVTDGERI 509
           ++I+D  ++  +++N+      P    +  V+TDG RI
Sbjct: 213 LSINDLPNLTQIIQNYKPFPQDPSLTPQIAVITDGSRI 250


>UniRef50_Q6AL43 Cluster: Related to NAD-dependent malic enzyme;
           n=1; Desulfotalea psychrophila|Rep: Related to
           NAD-dependent malic enzyme - Desulfotalea psychrophila
          Length = 578

 Score = 68.9 bits (161), Expect = 7e-11
 Identities = 31/86 (36%), Positives = 50/86 (58%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431
           +YI++  L DRN  L +  +  ++ + M I+YTPTVGLA QK+  ++R+  GL  +    
Sbjct: 81  KYIFIRSLFDRNVTLAHALIQSDLEKFMGIIYTPTVGLAVQKYSAMFRQANGLHFSPDTI 140

Query: 432 GHVYDVLKNWPETDVRAIVVTDGERI 509
               D+L+ +   D+R  VVTD + I
Sbjct: 141 DQAEDILRRFAHRDIRVAVVTDNQGI 166



 Score = 37.1 bits (82), Expect = 0.26
 Identities = 17/43 (39%), Positives = 24/43 (55%)
 Frame = +1

Query: 115 NKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYEN 243
           NK  AF+ +ER   G+ G LPP  +  E QVE C + +   E+
Sbjct: 35  NKSTAFSSKERDDFGLQGSLPPGFRDLEAQVENCHIKLGEKES 77


>UniRef50_A3YYQ0 Cluster: Malate oxidoreductase; n=1; Synechococcus
           sp. WH 5701|Rep: Malate oxidoreductase - Synechococcus
           sp. WH 5701
          Length = 517

 Score = 68.5 bits (160), Expect = 9e-11
 Identities = 36/93 (38%), Positives = 53/93 (56%), Gaps = 1/93 (1%)
 Frame = +3

Query: 234 IRKST*QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPR-GL 410
           +R    ++ + + L   N  LF+RF+AD++  +MPIVYTPTVG A Q+F L YR P  G+
Sbjct: 18  LRNDLERFRFAVALRQANLTLFHRFLADHIEAVMPIVYTPTVGAAIQRFSLDYRTPSGGV 77

Query: 411 FITIHDKGHVYDVLKNWPETDVRAIVVTDGERI 509
           F+   D   +  VL       V  I++TD + I
Sbjct: 78  FLAAPDLERIESVLSQAATGPVDLILITDSQGI 110


>UniRef50_A2QY66 Cluster: Malic enzyme; n=2; cellular organisms|Rep:
           Malic enzyme - Aspergillus niger
          Length = 609

 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 35/114 (30%), Positives = 63/114 (55%), Gaps = 1/114 (0%)
 Frame = +3

Query: 171 VTTTSQDARGAG*TMQALDRQIRKST*QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYT 350
           + T  +  + A     + D  + K+T    ++  +  +NE L+Y+ +  ++ EM+ I+YT
Sbjct: 90  IQTLEEQVQRAYEQYSSRDNDLAKNT----FMASMKAQNEVLYYKLIDTHLKEMLSIIYT 145

Query: 351 PTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPE-TDVRAIVVTDGERI 509
           PT G A Q +  ++R+P G F+ I D+  + + L N+    +V  IVV+DGE I
Sbjct: 146 PTEGDAIQNYSRLFRKPEGCFLNIRDQDRIEECLSNFSRGEEVDYIVVSDGEEI 199



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 25/61 (40%), Positives = 34/61 (55%)
 Frame = +1

Query: 85  GLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNNTSI 264
           G D L+    NKG AFT EER+   +HGLLPP ++T EEQV+         +N L   + 
Sbjct: 57  GRDALQSCQFNKGSAFTEEERKTFKLHGLLPPNIQTLEEQVQRAYEQYSSRDNDLAKNTF 116

Query: 265 L 267
           +
Sbjct: 117 M 117


>UniRef50_P40375 Cluster: NAD-dependent malic enzyme; n=3;
           Schizosaccharomyces pombe|Rep: NAD-dependent malic
           enzyme - Schizosaccharomyces pombe (Fission yeast)
          Length = 565

 Score = 63.3 bits (147), Expect = 3e-09
 Identities = 32/87 (36%), Positives = 53/87 (60%), Gaps = 3/87 (3%)
 Frame = +3

Query: 258 IYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITI--HDK 431
           +YL  L   N+ LFY  ++ ++ EM+PI+YTPT G A ++F  +YR P G ++ I  +D 
Sbjct: 74  LYLSQLSVTNQTLFYALISQHLIEMIPIIYTPTEGDAIKQFSDIYRYPEGCYLDIDHNDL 133

Query: 432 GHVYDVLKNWPETD-VRAIVVTDGERI 509
            ++   L  + ++D V  I++TD E I
Sbjct: 134 SYIKQQLSEFGKSDSVEYIIITDSEGI 160



 Score = 43.2 bits (97), Expect = 0.004
 Identities = 22/46 (47%), Positives = 27/46 (58%)
 Frame = +1

Query: 79  LSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELC 216
           L G+  L  P  NK  AFT EERQ   I   LPP V+T ++QV+ C
Sbjct: 13  LKGVTLLNSPRYNKDTAFTPEERQKFEISSRLPPIVETLQQQVDRC 58


>UniRef50_Q7K3R0 Cluster: Malic enzyme; n=2; Sophophora|Rep: Malic
           enzyme - Drosophila melanogaster (Fruit fly)
          Length = 633

 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 26/57 (45%), Positives = 37/57 (64%)
 Frame = +1

Query: 73  SGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYEN 243
           S + GL  L     NKG+AFT+ ER++L IHGLLP  V+T +EQ E+C   ++ + N
Sbjct: 68  SKVDGLWMLNQSNYNKGLAFTLNERRVLSIHGLLPVAVRTIDEQAEICSNLLESFTN 124



 Score = 56.0 bits (129), Expect = 5e-07
 Identities = 29/86 (33%), Positives = 43/86 (50%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431
           QYIYL  L  RN  LFY  +  N    +P+              +++   +GL+I I D 
Sbjct: 128 QYIYLTYLSRRNRRLFYYLLLSNPDRFVPMTDASGSIDLLMVHRMIHSMGQGLYICIKDL 187

Query: 432 GHVYDVLKNWPETDVRAIVVTDGERI 509
           GHV  +L NWP   VR ++V++G  +
Sbjct: 188 GHVSQILSNWPFRCVRCLLVSNGASV 213


>UniRef50_Q48796 Cluster: Malolactic enzyme; n=49; Bacteria|Rep:
           Malolactic enzyme - Oenococcus oeni (Leuconostoc oenos)
          Length = 541

 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 29/92 (31%), Positives = 50/92 (54%), Gaps = 2/92 (2%)
 Frame = +3

Query: 258 IYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRG-LFITIHDKG 434
           ++LM + + N  LFY+  + +V E MPIVY PT+    + +  ++  P+G  F+ I+   
Sbjct: 62  LFLMEIFNTNHVLFYKLFSQHVVEFMPIVYDPTIADTIENYSELFVEPQGAAFLDINHPE 121

Query: 435 HVYDVLKNWPE-TDVRAIVVTDGERIWVWATW 527
           ++   LKN     D++ +VV+D E I     W
Sbjct: 122 NIQSTLKNAANGRDIKLLVVSDAEGILGIGDW 153



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 20/38 (52%), Positives = 28/38 (73%)
 Frame = +1

Query: 97  LKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVE 210
           L  P +NKG AFT  ER+ LG++GLLP +V+  +EQV+
Sbjct: 8   LNDPFINKGTAFTEAEREELGLNGLLPAKVQALQEQVD 45


>UniRef50_Q2HCG7 Cluster: Malic enzyme; n=1; Chaetomium
           globosum|Rep: Malic enzyme - Chaetomium globosum (Soil
           fungus)
          Length = 586

 Score = 56.8 bits (131), Expect = 3e-07
 Identities = 34/98 (34%), Positives = 54/98 (55%), Gaps = 3/98 (3%)
 Frame = +3

Query: 210 TMQALDRQIRKST*QYIYLMGLLDRNEHLFYRFVADNVA--EMMPIVYTPTVGLACQKFG 383
           ++Q LD+Q++++  QY      L +N  L      + V   +M  +VYTPT G A + F 
Sbjct: 65  SIQTLDQQVQRAYEQYSARPDDLAKNTFLTSMKEQNEVLYFKMFSVVYTPTEGDAIENFS 124

Query: 384 LVYRRPRGLFITIHDKGHVYDVLKNW-PETDVRAIVVT 494
            ++RRP+G+F+ +HD   V+  L  W    D+  IVVT
Sbjct: 125 RLFRRPQGVFLNVHDCDRVHHDLSLWGMPDDIDYIVVT 162



 Score = 41.5 bits (93), Expect = 0.012
 Identities = 22/53 (41%), Positives = 29/53 (54%)
 Frame = +1

Query: 52  SGDGQPTSGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVE 210
           S  G     L G   L H   NKG AFT EER+   + GLLP  ++T ++QV+
Sbjct: 22  STSGPLECALKGTVLLNHSYFNKGSAFTKEERRDFELSGLLPQSIQTLDQQVQ 74


>UniRef50_Q5CS07 Cluster: Malic enzyme; n=2; Cryptosporidium|Rep:
           Malic enzyme - Cryptosporidium parvum Iowa II
          Length = 614

 Score = 56.4 bits (130), Expect = 4e-07
 Identities = 30/90 (33%), Positives = 49/90 (54%), Gaps = 4/90 (4%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGL--VYRR--PRGLFIT 419
           +Y +L  +   +  LF+  +     ++ P+VYTPTVG  C +F      R     GL++ 
Sbjct: 122 KYTFLENIRSSSFILFHSLLDKYFKDLTPLVYTPTVGEGCIEFSRNPTIRNWLGSGLYLN 181

Query: 420 IHDKGHVYDVLKNWPETDVRAIVVTDGERI 509
              KG +Y++LK++   D+  IV+TDG RI
Sbjct: 182 KSHKGRIYEILKDFKSDDIEIIVLTDGGRI 211



 Score = 52.0 bits (119), Expect = 8e-06
 Identities = 23/63 (36%), Positives = 42/63 (66%)
 Frame = +1

Query: 79  LSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNNT 258
           L G++ L++P  NKG++FT+EER+  G+ GLLP + +T +EQV     +I++ ++ +   
Sbjct: 64  LKGIELLRNPFYNKGLSFTMEERKEYGLEGLLPAKYETIDEQVSRLWTAINKIDSNIGKY 123

Query: 259 SIL 267
           + L
Sbjct: 124 TFL 126


>UniRef50_A4RZU1 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
           enzyme - Ostreococcus lucimarinus CCE9901
          Length = 539

 Score = 55.6 bits (128), Expect = 7e-07
 Identities = 26/63 (41%), Positives = 36/63 (57%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 431
           +Y+YL  L   +   FYR +     E+MP VYTPTVG AC+K+  +     G++IT  D 
Sbjct: 20  RYVYLRELQRASAETFYRALVREPLELMPFVYTPTVGEACEKYHRLGIETNGVYITADDA 79

Query: 432 GHV 440
           G V
Sbjct: 80  GRV 82


>UniRef50_Q8Y5Y8 Cluster: Lmo1915 protein; n=15; Firmicutes|Rep:
           Lmo1915 protein - Listeria monocytogenes
          Length = 547

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 26/62 (41%), Positives = 38/62 (61%)
 Frame = +1

Query: 82  SGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNNTS 261
           SG D++ +P LNKG AF+ EER    + GLLPP ++T E+Q    +  I+  E PL+   
Sbjct: 5   SGFDYMNNPLLNKGTAFSKEERASYQLDGLLPPIIETIEQQAVRIETQIENLETPLHKHR 64

Query: 262 IL 267
           +L
Sbjct: 65  LL 66



 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 29/92 (31%), Positives = 47/92 (51%), Gaps = 3/92 (3%)
 Frame = +3

Query: 264 LMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRP-RGLFITIHDKGHV 440
           L  L + N  L+Y  V  NV + +PI+YTPT+G A  ++   Y  P   LF+       +
Sbjct: 66  LTNLYNENRTLYYYVVTKNVTDYLPIIYTPTIGDAVIQYHKDYTAPDEALFVDAFAPEKL 125

Query: 441 YDVLKNWPET--DVRAIVVTDGERIWVWATWA 530
              +KN+ +   ++  IV+TDGE +     W+
Sbjct: 126 SASIKNYAKNNPNIDMIVITDGEGVLGIGDWS 157


>UniRef50_Q5KBK5 Cluster: Nad-dependent malic enzyme, putative; n=2;
           Filobasidiella neoformans|Rep: Nad-dependent malic
           enzyme, putative - Cryptococcus neoformans
           (Filobasidiella neoformans)
          Length = 584

 Score = 52.4 bits (120), Expect = 6e-06
 Identities = 30/84 (35%), Positives = 45/84 (53%), Gaps = 1/84 (1%)
 Frame = +3

Query: 261 YLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFIT-IHDKGH 437
           +L  +  +N  LFY  +  ++ EM PIVYTPT   A   +  ++RR  GL++T   +K  
Sbjct: 87  FLQSMKAQNWTLFYALLQAHLVEMFPIVYTPTEADAIADYSHLFRRSEGLYLTPPGEKNM 146

Query: 438 VYDVLKNWPETDVRAIVVTDGERI 509
             D L      ++  IVV+DGE I
Sbjct: 147 EEDFLDACEGRELELIVVSDGEAI 170



 Score = 34.7 bits (76), Expect = 1.4
 Identities = 23/61 (37%), Positives = 34/61 (55%)
 Frame = +1

Query: 97  LKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNNTSILWGS 276
           L +P  NKG AFT +ER    + G LP  V + E QV   K + ++Y++    T+IL  S
Sbjct: 32  LNNPRFNKGSAFTHQERSEFALRGRLPYAVDSLEIQV---KRAYEQYKS--RETNILKNS 86

Query: 277 W 279
           +
Sbjct: 87  F 87


>UniRef50_Q5KEY3 Cluster: Malic enzyme; n=1; Filobasidiella
           neoformans|Rep: Malic enzyme - Cryptococcus neoformans
           (Filobasidiella neoformans)
          Length = 629

 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 31/102 (30%), Positives = 54/102 (52%), Gaps = 16/102 (15%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHD- 428
           ++ +L  L D+N+ LFYR + D + E++ ++YTP    A   +  ++RRP G +I+  + 
Sbjct: 108 KHAFLASLRDQNQVLFYRLMQDRLKELLGVLYTPGAAEAVAGYSSLFRRPVGCYISFPNQ 167

Query: 429 -------KGHVYDVLK--------NWPETDVRAIVVTDGERI 509
                  +GH+ DV +        N P+  +  +VVTD E I
Sbjct: 168 DGMRAQLEGHLTDVNRTADVAYDSNKPDDAIDLVVVTDAEAI 209



 Score = 41.5 bits (93), Expect = 0.012
 Identities = 21/44 (47%), Positives = 26/44 (59%)
 Frame = +1

Query: 73  SGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQ 204
           + L G   L  P LNKG  FT EERQ+ G+ G LP  V + E+Q
Sbjct: 48  TNLRGSALLNTPRLNKGAGFTREERQIFGLEGFLPYDVHSLEKQ 91


>UniRef50_P36013 Cluster: NAD-dependent malic enzyme, mitochondrial
           precursor; n=15; Saccharomycetales|Rep: NAD-dependent
           malic enzyme, mitochondrial precursor - Saccharomyces
           cerevisiae (Baker's yeast)
          Length = 669

 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 26/84 (30%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
 Frame = +3

Query: 261 YLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHV 440
           ++  L  +N+ L++  +  ++ E++PI+YTPT G A   +   +R+P G+F+ I +   +
Sbjct: 159 FMTSLRVQNKVLYFALIRRHIKELVPIIYTPTEGDAIAAYSHRFRKPEGVFLDITEPDSI 218

Query: 441 YDVLKNW-PETDVRAIVVTDGERI 509
              L  +  + DV  IVV+D E I
Sbjct: 219 ECRLATYGGDKDVDYIVVSDSEGI 242



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 23/57 (40%), Positives = 30/57 (52%)
 Frame = +1

Query: 79  LSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPL 249
           L     L  P  NKG AFT EER+   +  LLPP+V T +EQ+E     +   + PL
Sbjct: 98  LESFQLLNSPLFNKGSAFTQEEREAFNLEALLPPQVNTLDEQLERSYKQLCYLKTPL 154


>UniRef50_Q9S4T5 Cluster: NAD-malate oxidoreductase homolog; n=15;
           Legionellales|Rep: NAD-malate oxidoreductase homolog -
           Legionella pneumophila
          Length = 117

 Score = 48.0 bits (109), Expect = 1e-04
 Identities = 19/39 (48%), Positives = 30/39 (76%)
 Frame = +3

Query: 252 QYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLA 368
           Q+IYL  L D+N+ +FY+ ++ ++ EM+PI+YTP VG A
Sbjct: 79  QHIYLNNLHDKNQIVFYKLLSRHLGEMLPIIYTPIVGAA 117



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 27/59 (45%), Positives = 33/59 (55%)
 Frame = +1

Query: 73  SGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPL 249
           + L G   L  P LNKG AFT EER+  G+ G LP RV+T +EQV+   L    Y   L
Sbjct: 19  TSLCGKPLLTTPQLNKGTAFTQEERKDFGLLGKLPHRVETLDEQVKRAYLQYSSYTTRL 77


>UniRef50_Q8S484 Cluster: Putative NADP-dependent malic enzyme; n=1;
           Zea mays|Rep: Putative NADP-dependent malic enzyme - Zea
           mays (Maize)
          Length = 309

 Score = 46.4 bits (105), Expect = 4e-04
 Identities = 29/75 (38%), Positives = 37/75 (49%)
 Frame = +3

Query: 285 NEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWP 464
           +E LFY+ + DNV E++P VYT T                         G V DVLKNWP
Sbjct: 225 DERLFYKLLIDNVVELLPFVYTTT-------------------------GKVLDVLKNWP 259

Query: 465 ETDVRAIVVTDGERI 509
             +++ I VTD ERI
Sbjct: 260 HRNIQVIFVTDSERI 274


>UniRef50_UPI0000DB7FF6 Cluster: PREDICTED: hypothetical protein,
           partial; n=1; Apis mellifera|Rep: PREDICTED:
           hypothetical protein, partial - Apis mellifera
          Length = 95

 Score = 41.9 bits (94), Expect = 0.009
 Identities = 19/37 (51%), Positives = 26/37 (70%)
 Frame = +1

Query: 10  TYSEMERDRIGL*GSGDGQPTSGLSGLDHLKHPGLNK 120
           T S ++RD++G  G GD   ++ L GLDHLK+P LNK
Sbjct: 59  TMSSVQRDQLGQRGHGDAMCSNLLRGLDHLKNPRLNK 95


>UniRef50_Q4SHK3 Cluster: Chromosome 5 SCAF14581, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 5 SCAF14581, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 72

 Score = 33.9 bits (74), Expect = 2.4
 Identities = 19/50 (38%), Positives = 24/50 (48%)
 Frame = -1

Query: 218 LHSSTCSSCVLTRGGNNPCMPKS*RSSMVKAMPLLRPGCLRWSRPERPLV 69
           L  S  SS   +RG   P  P    SS ++     R G  RWSRP RP++
Sbjct: 22  LKGSAASSAAASRGQKTPASPTVPGSSQLQT----RSGQARWSRPRRPML 67


>UniRef50_Q7WLT2 Cluster: Putative uncharacterized protein; n=1;
           Bordetella bronchiseptica|Rep: Putative uncharacterized
           protein - Bordetella bronchiseptica (Alcaligenes
           bronchisepticus)
          Length = 215

 Score = 33.9 bits (74), Expect = 2.4
 Identities = 16/38 (42%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
 Frame = +3

Query: 426 DKGHVYDVLKNWP-ETDVRAIVVTDGERIWVWATWAHA 536
           D GH + V K+ P E  V+      G+R+WV  TWA+A
Sbjct: 49  DDGHAFMVYKHMPHERAVKCPYGQPGDRLWVRETWAYA 86


>UniRef50_A1CKF3 Cluster: Stress response protein (Ish1), putative;
           n=5; Pezizomycotina|Rep: Stress response protein (Ish1),
           putative - Aspergillus clavatus
          Length = 516

 Score = 33.9 bits (74), Expect = 2.4
 Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 1/53 (1%)
 Frame = -1

Query: 410 EAPW-SAVHKPELLTGQANRRSVHNWHHFSHVIRDETVEQMLIAVQEPHKIDV 255
           +A W S V KP    GQA   + HNWHH    I D   +  L A  + H + V
Sbjct: 63  KANWDSKVQKP---LGQAAEHTTHNWHHAKEWIFDTWSDSQLKAFLDRHGVPV 112


>UniRef50_Q4RNM6 Cluster: Chromosome 21 SCAF15012, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 21 SCAF15012, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 1187

 Score = 33.5 bits (73), Expect = 3.1
 Identities = 20/51 (39%), Positives = 26/51 (50%)
 Frame = -1

Query: 236 YLSIESLHSSTCSSCVLTRGGNNPCMPKS*RSSMVKAMPLLRPGCLRWSRP 84
           Y S+ES +  T  SC L   G+   +P+S RSS      L RP   +WS P
Sbjct: 255 YNSLESSYQRTLQSC-LKSSGSVASLPQSDRSSSSSQESLNRPLTSKWSAP 304


>UniRef50_UPI0001560FE5 Cluster: PREDICTED: similar to KIAA2007
           protein; n=2; Equus caballus|Rep: PREDICTED: similar to
           KIAA2007 protein - Equus caballus
          Length = 745

 Score = 33.1 bits (72), Expect = 4.2
 Identities = 19/49 (38%), Positives = 24/49 (48%)
 Frame = -1

Query: 203 CSSCVLTRGGNNPCMPKS*RSSMVKAMPLLRPGCLRWSRPERPLVGCPS 57
           C+S V      +   P+  RSS    +PLLRP  LR+S P  P   C S
Sbjct: 167 CASLVRASASPSRLFPRR-RSSSAVRVPLLRPLALRFSGPATPPCACES 214


>UniRef50_Q7QQ11 Cluster: GLP_227_10956_9892; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_227_10956_9892 - Giardia lamblia
           ATCC 50803
          Length = 354

 Score = 33.1 bits (72), Expect = 4.2
 Identities = 32/119 (26%), Positives = 54/119 (45%)
 Frame = -1

Query: 431 LIVDRDEEAPWSAVHKPELLTGQANRRSVHNWHHFSHVIRDETVEQMLIAVQEPHKIDVL 252
           L VD  +   WSA+ +P +     N+R  H    F+  ++++   +   +V     +  L
Sbjct: 159 LFVDMFDNIVWSAI-RPCVFVLAFNKRE-HIV--FTVTLKEDQSAKDAYSVLVHDDVHKL 214

Query: 251 LSGFSYLSIESLHSSTCSSCVLTRGGNNPCMPKS*RSSMVKAMPLLRPGCLRWSRPERP 75
            SG S LSI ++ S+   SCV      NP   K    + ++++ L+R      SRP  P
Sbjct: 215 ASGLSALSIANITSTDLDSCVCCISSVNPLESKDGLINKIQSLLLIRA-----SRPTTP 268


>UniRef50_Q1EI20 Cluster: Putative uncharacterized protein; n=2;
           root|Rep: Putative uncharacterized protein - uncultured
           organism
          Length = 302

 Score = 32.7 bits (71), Expect = 5.5
 Identities = 10/20 (50%), Positives = 16/20 (80%)
 Frame = +3

Query: 405 GLFITIHDKGHVYDVLKNWP 464
           G+++TI + G + D+LKNWP
Sbjct: 210 GVYLTIREPGQITDILKNWP 229


>UniRef50_A0WC26 Cluster: Multi-sensor hybrid histidine kinase
           precursor; n=2; Geobacter lovleyi SZ|Rep: Multi-sensor
           hybrid histidine kinase precursor - Geobacter lovleyi SZ
          Length = 1007

 Score = 32.7 bits (71), Expect = 5.5
 Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
 Frame = +3

Query: 360 GLACQKFGLVYRRPRGL-FITIHDKGHVYDVLKNWPETDVRAIVVTDG 500
           G+   K   +YR  R   FI  HD+ H+++ +KN PE  +  IV  DG
Sbjct: 198 GIFDSKGVFLYRTARANEFIGKHDQPHLFEQMKNGPEEGIIDIVSNDG 245


>UniRef50_UPI0000F2DA74 Cluster: PREDICTED: hypothetical protein;
           n=1; Monodelphis domestica|Rep: PREDICTED: hypothetical
           protein - Monodelphis domestica
          Length = 380

 Score = 32.3 bits (70), Expect = 7.3
 Identities = 17/35 (48%), Positives = 21/35 (60%)
 Frame = -1

Query: 134 VKAMPLLRPGCLRWSRPERPLVGCPSPEPYNPIRS 30
           VKA P   PG    SRPERP    P+P  ++P+RS
Sbjct: 92  VKARPEACPGPAACSRPERP----PTPRSFHPLRS 122


>UniRef50_Q4SBA5 Cluster: Chromosome undetermined SCAF14676, whole
           genome shotgun sequence; n=2; Tetraodontidae|Rep:
           Chromosome undetermined SCAF14676, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 224

 Score = 32.3 bits (70), Expect = 7.3
 Identities = 17/44 (38%), Positives = 23/44 (52%)
 Frame = +1

Query: 358 LAWPVRSSGLCTADQGASSSRSTIRDMYTMFLRTGRRRTSVPLL 489
           L WP+   G  +  QG SS R+T+ D     L  G R  S+PL+
Sbjct: 16  LLWPLHRRGNPSLKQGFSSQRATLVDSLLEELHQGPRPFSLPLM 59


>UniRef50_Q1MKF6 Cluster: Putative uncharacterized protein; n=1;
           Rhizobium leguminosarum bv. viciae 3841|Rep: Putative
           uncharacterized protein - Rhizobium leguminosarum bv.
           viciae (strain 3841)
          Length = 337

 Score = 32.3 bits (70), Expect = 7.3
 Identities = 17/55 (30%), Positives = 24/55 (43%)
 Frame = +1

Query: 166 GLLPPRVKTQEEQVELCKLSIDRYENPLNNTSILWGSWTAMSICSTVSSRITWLK 330
           GL+PPR+  Q  Q  + K+ I   +N + +  I WG     S    V     W K
Sbjct: 243 GLIPPRLNKQYNQHPISKIIIQSVQNRMPDELIFWGIGLTDSDVDLVELYKAWSK 297


>UniRef50_Q0RK68 Cluster: Type I polyketide synthase; n=2;
            Frankia|Rep: Type I polyketide synthase - Frankia alni
            (strain ACN14a)
          Length = 2157

 Score = 31.9 bits (69), Expect = 9.6
 Identities = 18/50 (36%), Positives = 23/50 (46%)
 Frame = +1

Query: 31   DRIGL*GSGDGQPTSGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPP 180
            DR+G+   G       L G  H  HP L  G+A T+   Q LG  G+  P
Sbjct: 1298 DRVGIDRVGGVVSLLALDGTPHPDHPHLTTGLALTVTGVQALGDLGVGAP 1347


>UniRef50_A4X664 Cluster: GCN5-related N-acetyltransferase; n=2;
           Salinispora|Rep: GCN5-related N-acetyltransferase -
           Salinispora tropica CNB-440
          Length = 182

 Score = 31.9 bits (69), Expect = 9.6
 Identities = 24/82 (29%), Positives = 35/82 (42%), Gaps = 2/82 (2%)
 Frame = -1

Query: 518 PDPDTFSVGYNNGT--DVRLRPVLKNIVYMSLIVDRDEEAPWSAVHKPELLTGQANRRSV 345
           P P  F   Y+     D+RLRPVL + +    +  +D EA W A   P      A+R + 
Sbjct: 3   PRPGVFGRSYHRAVSADLRLRPVLDDDLPFFFLHQQDVEASWMAAFGP---ADPADRTAF 59

Query: 344 HNWHHFSHVIRDETVEQMLIAV 279
               H+  +  D TV    + V
Sbjct: 60  D--AHWKRIRTDPTVVSRTVVV 79


>UniRef50_Q4Q8F5 Cluster: Putative uncharacterized protein; n=6;
           Trypanosomatidae|Rep: Putative uncharacterized protein -
           Leishmania major
          Length = 629

 Score = 31.9 bits (69), Expect = 9.6
 Identities = 21/66 (31%), Positives = 30/66 (45%), Gaps = 1/66 (1%)
 Frame = +1

Query: 103 HPGLNKGMA-FTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNNTSILWGSW 279
           HPG    +  F   ER+L  IH +L  +VK Q     L +  +     P +NT +LW   
Sbjct: 83  HPGFQADVCIFDFAERRL--IHRMLLHKVKVQALAFSLDEQYLASVGGPDDNTVVLWDVK 140

Query: 280 TAMSIC 297
           T   +C
Sbjct: 141 TGRPLC 146


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 620,980,677
Number of Sequences: 1657284
Number of extensions: 13844296
Number of successful extensions: 40984
Number of sequences better than 10.0: 74
Number of HSP's better than 10.0 without gapping: 39301
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 40963
length of database: 575,637,011
effective HSP length: 96
effective length of database: 416,537,747
effective search space used: 34156095254
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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