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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= NV021814X
         (567 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI000151E1BA Cluster: UDP-glucose dehydrogenase; n=3; ...   140   3e-32
UniRef50_O60701 Cluster: UDP-glucose 6-dehydrogenase; n=138; cel...   138   6e-32
UniRef50_Q9FM01 Cluster: UDP-glucose dehydrogenase; n=8; Eukaryo...   138   8e-32
UniRef50_Q10CK6 Cluster: UDP-glucose 6-dehydrogenase, putative, ...   132   4e-30
UniRef50_A2BXW7 Cluster: UDP-glucose 6-dehydrogenase; n=1; Proch...   117   2e-25
UniRef50_Q0CZ88 Cluster: UDP-glucose 6-dehydrogenase; n=2; Asper...   101   1e-20
UniRef50_A3AK92 Cluster: Putative uncharacterized protein; n=2; ...    99   6e-20
UniRef50_A0C8G1 Cluster: Chromosome undetermined scaffold_158, w...    91   2e-17
UniRef50_Q7S3T1 Cluster: Putative uncharacterized protein NCU049...    88   2e-16
UniRef50_UPI0001509F86 Cluster: UDP-glucose/GDP-mannose dehydrog...    82   1e-14
UniRef50_Q7S3L5 Cluster: Putative uncharacterized protein NCU082...    77   4e-13
UniRef50_Q2UR48 Cluster: UDP-glucose/GDP-mannose dehydrogenase; ...    77   4e-13
UniRef50_A2QGJ1 Cluster: Contig An03c0120, complete genome. prec...    69   8e-11
UniRef50_A1C8W5 Cluster: UDP-glucose dehydrogenase Ugd1, putativ...    60   5e-08
UniRef50_Q4FLP8 Cluster: UDPglucose 6-dehydrogenase; n=2; Candid...    54   3e-06
UniRef50_Q6MAI0 Cluster: Probable UDPglucose 6-dehydrogenase; n=...    53   4e-06
UniRef50_Q191B5 Cluster: UDP-glucose/GDP-mannose dehydrogenase p...    53   5e-06
UniRef50_Q5ARA8 Cluster: Putative uncharacterized protein; n=1; ...    52   1e-05
UniRef50_O86422 Cluster: UDP-glucose 6-dehydrogenase; n=137; Bac...    52   1e-05
UniRef50_Q5KUU7 Cluster: NDP-suger dehydrogenase; n=15; Firmicut...    51   2e-05
UniRef50_A1S0Y4 Cluster: UDP-glucose 6-dehydrogenase; n=1; Therm...    51   2e-05
UniRef50_Q2W9U5 Cluster: Predicted UDP-glucose 6-dehydrogenase; ...    51   2e-05
UniRef50_O32271 Cluster: UDP-glucose 6-dehydrogenase; n=5; Bacil...    51   2e-05
UniRef50_Q7MVC7 Cluster: Sugar dehydrogenase, UDP-glucose/GDP-ma...    50   3e-05
UniRef50_O34862 Cluster: YtcA; n=5; Bacillaceae|Rep: YtcA - Baci...    50   3e-05
UniRef50_Q5WD59 Cluster: UDP-glucose 6-dehydrogenase; n=1; Bacil...    50   4e-05
UniRef50_Q8EMC5 Cluster: NDP-sugar dehydrogenase; n=2; Bacillace...    50   5e-05
UniRef50_Q2S4Z2 Cluster: UDP-glucose dehydrogenase; n=1; Salinib...    48   2e-04
UniRef50_A7HFB2 Cluster: UDP-glucose 6-dehydrogenase; n=4; Bacte...    48   2e-04
UniRef50_A6Q2Z6 Cluster: UDP-glucose 6-dehydrogenase; n=3; cellu...    48   2e-04
UniRef50_A2QSA3 Cluster: Catalytic activity: UDP-glucose + 2 NAD...    48   2e-04
UniRef50_Q0CCH6 Cluster: Predicted protein; n=1; Aspergillus ter...    47   3e-04
UniRef50_Q11EL7 Cluster: UDP-glucose/GDP-mannose dehydrogenase; ...    47   4e-04
UniRef50_Q9RGJ9 Cluster: UDP-ManNAc dehydrogenase; n=15; Bacteri...    46   6e-04
UniRef50_Q2BE06 Cluster: Nucleotide sugar dehydrogenase; n=1; Ba...    46   6e-04
UniRef50_Q67RC3 Cluster: UDP-glucose dehydrogenase; n=1; Symbiob...    46   8e-04
UniRef50_Q2NHK2 Cluster: Predicted UDP-N-acetyl-D-mannosaminuron...    45   0.001
UniRef50_O26924 Cluster: UDP-N-acetyl-D-mannosaminuronic acid de...    45   0.001
UniRef50_A4FX80 Cluster: UDP-glucose 6-dehydrogenase; n=3; Metha...    45   0.001
UniRef50_O66443 Cluster: Nucleotide sugar dehydrogenase; n=11; B...    45   0.001
UniRef50_Q84AP5 Cluster: UDP-N-acetyl-D-mannosaminuronic acid de...    45   0.001
UniRef50_Q81K29 Cluster: UDP-N-acetyl-D-mannosamine dehydrogenas...    44   0.003
UniRef50_O29659 Cluster: UDP-glucose dehydrogenase; n=15; Euryar...    44   0.003
UniRef50_Q2JWZ7 Cluster: UDP-glucose dehydrogenase; n=3; Cyanoba...    43   0.004
UniRef50_Q2FTB3 Cluster: UDP-glucose 6-dehydrogenase; n=1; Metha...    43   0.006
UniRef50_Q89GP9 Cluster: Blr6296 protein; n=4; Bacteria|Rep: Blr...    42   0.010
UniRef50_Q1J352 Cluster: UDP-glucose 6-dehydrogenase; n=3; cellu...    42   0.010
UniRef50_Q98C77 Cluster: UDP-glucose dehydrogenase; n=4; Proteob...    42   0.013
UniRef50_Q1QJ09 Cluster: UDP-glucose/GDP-mannose dehydrogenase; ...    42   0.013
UniRef50_Q58454 Cluster: Uncharacterized protein MJ1054 (EC 1.1....    42   0.013
UniRef50_Q02BK7 Cluster: UDP-glucose/GDP-mannose dehydrogenase; ...    41   0.018
UniRef50_Q9UXJ6 Cluster: Udp-glucose dehydrogenase; n=2; Sulfolo...    41   0.018
UniRef50_Q8PXP4 Cluster: UDP-N-acetyl-D-mannosamine 6-dehydrogen...    41   0.023
UniRef50_Q1IJZ4 Cluster: UDP-glucose 6-dehydrogenase precursor; ...    40   0.031
UniRef50_Q5UXR5 Cluster: UDP-glucose 6-dehydrogenase; n=4; Halob...    40   0.031
UniRef50_Q3IN79 Cluster: UDP-glucose 6-dehydrogenase 1; n=2; Hal...    40   0.031
UniRef50_Q83D92 Cluster: UDP-glucose 6-dehydrogenase; n=4; Gamma...    40   0.054
UniRef50_Q7NLQ9 Cluster: UDP-glucose dehydrogenase; n=19; Bacter...    40   0.054
UniRef50_Q4UK39 Cluster: UDP-glucose 6-dehydrogenase; n=10; Rick...    40   0.054
UniRef50_O54068 Cluster: UDP-glucose 6-dehydrogenase; n=105; Bac...    40   0.054
UniRef50_A0V0Q2 Cluster: UDP-glucose 6-dehydrogenase precursor; ...    39   0.071
UniRef50_A1R406 Cluster: UDP-glucose 6-dehydrogenase; n=1; Arthr...    39   0.094
UniRef50_Q8U0F8 Cluster: NDP-sugar dehydrogenase; n=4; Thermococ...    38   0.16 
UniRef50_Q56812 Cluster: UDP-glucose dehydrogenase; n=1; Xanthom...    38   0.22 
UniRef50_Q4E8E3 Cluster: UDP-glucose 6-dehydrogenase; n=5; Wolba...    38   0.22 
UniRef50_Q5P7V5 Cluster: UDP-glucose dehydrogenase; n=12; Bacter...    37   0.29 
UniRef50_Q07RH1 Cluster: UDP-glucose/GDP-mannose dehydrogenase; ...    37   0.29 
UniRef50_A3YS39 Cluster: UDP-glucose 6-dehydrogenase; n=2; Campy...    37   0.38 
UniRef50_A1GFD3 Cluster: UDP-glucose 6-dehydrogenase; n=4; Actin...    36   0.66 
UniRef50_A0JTU3 Cluster: UDP-glucose 6-dehydrogenase precursor; ...    35   1.2  
UniRef50_UPI000058904C Cluster: PREDICTED: hypothetical protein;...    35   1.5  
UniRef50_Q4K1X3 Cluster: UDP-N-acetylmannosamine dehydrogenase M...    35   1.5  
UniRef50_Q57871 Cluster: Uncharacterized protein MJ0428; n=6; Me...    35   1.5  
UniRef50_A5UTQ6 Cluster: UDP-glucose/GDP-mannose dehydrogenase; ...    34   2.0  
UniRef50_Q9PCZ8 Cluster: UDP-glucose dehydrogenase; n=51; cellul...    34   2.7  
UniRef50_Q0AZ93 Cluster: UDP-glucose 6-dehydrogenase; n=1; Syntr...    34   2.7  
UniRef50_Q45410 Cluster: NDP-N-acetyl-D-galactosaminuronic acid ...    34   2.7  
UniRef50_Q89A08 Cluster: Putative uncharacterized protein; n=1; ...    33   4.7  
UniRef50_A6RSN0 Cluster: Putative uncharacterized protein; n=2; ...    33   6.2  
UniRef50_A6QYI2 Cluster: Predicted protein; n=1; Ajellomyces cap...    33   6.2  
UniRef50_Q0W3C1 Cluster: NDP-N-acetyl-D-galactosaminuronic acid ...    33   6.2  
UniRef50_A7P8X7 Cluster: Chromosome chr3 scaffold_8, whole genom...    32   8.1  
UniRef50_Q8N8W3 Cluster: CDNA FLJ38763 fis, clone KIDNE2014119; ...    32   8.1  

>UniRef50_UPI000151E1BA Cluster: UDP-glucose dehydrogenase; n=3;
           Danio rerio|Rep: UDP-glucose dehydrogenase - Danio rerio
          Length = 311

 Score =  140 bits (338), Expect = 3e-32
 Identities = 63/93 (67%), Positives = 73/93 (78%)
 Frame = +1

Query: 268 IQKICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRE 447
           I+KICC+GAGYVGGPTCSVIA  CP I VTV D +E RIK WNSD LPIYEPGL++VV  
Sbjct: 4   IKKICCIGAGYVGGPTCSVIASMCPEITVTVVDVNESRIKAWNSDTLPIYEPGLNEVVLS 63

Query: 448 CRGKNLFFSTNIAESIREAD*YLYPLTRPTKTH 546
           CRGKNLFFST+I  +I+EAD     +  PTKT+
Sbjct: 64  CRGKNLFFSTDIDSAIKEADLVFISVNTPTKTY 96


>UniRef50_O60701 Cluster: UDP-glucose 6-dehydrogenase; n=138;
           cellular organisms|Rep: UDP-glucose 6-dehydrogenase -
           Homo sapiens (Human)
          Length = 494

 Score =  138 bits (335), Expect = 6e-32
 Identities = 62/93 (66%), Positives = 72/93 (77%)
 Frame = +1

Query: 268 IQKICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRE 447
           I+KICC+GAGYVGGPTCSVIA  CP I+VTV D +E RI  WNS  LPIYEPGL +VV  
Sbjct: 4   IKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVES 63

Query: 448 CRGKNLFFSTNIAESIREAD*YLYPLTRPTKTH 546
           CRGKNLFFSTNI ++I+EAD     +  PTKT+
Sbjct: 64  CRGKNLFFSTNIDDAIKEADLVFISVNTPTKTY 96


>UniRef50_Q9FM01 Cluster: UDP-glucose dehydrogenase; n=8;
           Eukaryota|Rep: UDP-glucose dehydrogenase - Arabidopsis
           thaliana (Mouse-ear cress)
          Length = 480

 Score =  138 bits (334), Expect = 8e-32
 Identities = 60/90 (66%), Positives = 73/90 (81%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRECR 453
           KICC+GAGYVGGPT +VIALKCP+I+V V D S  RI  WNSD+LPIYEPGLDD+V++CR
Sbjct: 3   KICCIGAGYVGGPTMAVIALKCPDIEVAVVDISVPRINAWNSDQLPIYEPGLDDIVKQCR 62

Query: 454 GKNLFFSTNIAESIREAD*YLYPLTRPTKT 543
           GKNLFFST++ + +READ     +  PTKT
Sbjct: 63  GKNLFFSTDVEKHVREADIVFVSVNTPTKT 92


>UniRef50_Q10CK6 Cluster: UDP-glucose 6-dehydrogenase, putative,
           expressed; n=1; Oryza sativa (japonica
           cultivar-group)|Rep: UDP-glucose 6-dehydrogenase,
           putative, expressed - Oryza sativa subsp. japonica
           (Rice)
          Length = 245

 Score =  132 bits (320), Expect = 4e-30
 Identities = 58/90 (64%), Positives = 72/90 (80%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRECR 453
           KICC+GAGYVGGPT +VIALKCP I+V V D S+ RI  WNS++LPIYEPGLD+VV+ECR
Sbjct: 3   KICCIGAGYVGGPTMAVIALKCPAIEVVVVDISKPRIDAWNSEQLPIYEPGLDEVVKECR 62

Query: 454 GKNLFFSTNIAESIREAD*YLYPLTRPTKT 543
           G+NLFFST++ + + EAD     +  PTKT
Sbjct: 63  GRNLFFSTDVEKHVAEADIIFVSVNTPTKT 92


>UniRef50_A2BXW7 Cluster: UDP-glucose 6-dehydrogenase; n=1;
           Prochlorococcus marinus str. MIT 9515|Rep: UDP-glucose
           6-dehydrogenase - Prochlorococcus marinus (strain MIT
           9515)
          Length = 465

 Score =  117 bits (282), Expect = 2e-25
 Identities = 52/95 (54%), Positives = 68/95 (71%), Gaps = 3/95 (3%)
 Frame = +1

Query: 268 IQKICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSD---KLPIYEPGLDDV 438
           I+ ICC+GAGYVGGPT +VIA  CP++ + V D + +RI  WN D   KLP++EPGL D+
Sbjct: 9   IKNICCIGAGYVGGPTMAVIAANCPDLIINVVDINIDRINSWNIDDLSKLPVFEPGLKDI 68

Query: 439 VRECRGKNLFFSTNIAESIREAD*YLYPLTRPTKT 543
           V +CRGKNLFFS+N+ E+I  AD     +  PTKT
Sbjct: 69  VEKCRGKNLFFSSNVEENIANADIIFISVNTPTKT 103


>UniRef50_Q0CZ88 Cluster: UDP-glucose 6-dehydrogenase; n=2;
           Aspergillus|Rep: UDP-glucose 6-dehydrogenase -
           Aspergillus terreus (strain NIH 2624)
          Length = 508

 Score =  101 bits (242), Expect = 1e-20
 Identities = 46/98 (46%), Positives = 69/98 (70%), Gaps = 4/98 (4%)
 Frame = +1

Query: 265 VIQKICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVR 444
           +I+KI C+GAG+VGGP  +V+A +CP I VTV DK+  RI+ WNSD LP+YEPGL +++ 
Sbjct: 1   MIRKITCIGAGFVGGPLGAVLAFQCPEITVTVVDKNPARIESWNSDDLPMYEPGLSELIA 60

Query: 445 ECRGK----NLFFSTNIAESIREAD*YLYPLTRPTKTH 546
           + R +    NL FS ++ ++I +AD  +  +  PTK+H
Sbjct: 61  QVRQRKDTCNLTFSCDVRKAIGDADFIMLCIDTPTKSH 98


>UniRef50_A3AK92 Cluster: Putative uncharacterized protein; n=2;
           Oryza sativa (japonica cultivar-group)|Rep: Putative
           uncharacterized protein - Oryza sativa subsp. japonica
           (Rice)
          Length = 438

 Score = 99.1 bits (236), Expect = 6e-20
 Identities = 43/75 (57%), Positives = 57/75 (76%)
 Frame = +1

Query: 319 SVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRECRGKNLFFSTNIAESIR 498
           +VIALKCP+++V V D S  RI+ WNS++LPIYEPGLDDVVR+CRG+NLFFST++   + 
Sbjct: 2   AVIALKCPDVEVVVVDISAPRIEGWNSERLPIYEPGLDDVVRQCRGRNLFFSTDVERHVA 61

Query: 499 EAD*YLYPLTRPTKT 543
           +A      +  PTKT
Sbjct: 62  DAGIVFVSVNTPTKT 76


>UniRef50_A0C8G1 Cluster: Chromosome undetermined scaffold_158,
           whole genome shotgun sequence; n=2; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_158,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 434

 Score = 91.1 bits (216), Expect = 2e-17
 Identities = 40/95 (42%), Positives = 63/95 (66%)
 Frame = +1

Query: 262 MVIQKICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVV 441
           M I+K+ C GAGYVGGPT +V+A KCP     V D +E++I++WNS + P+YE  LD+ V
Sbjct: 1   MQIKKVSCFGAGYVGGPTMAVMASKCPEQTFIVYDINEQQIQKWNSKQYPVYEENLDEYV 60

Query: 442 RECRGKNLFFSTNIAESIREAD*YLYPLTRPTKTH 546
            +   KNL F+++I  ++++ D     +  P+KT+
Sbjct: 61  NKTIHKNLIFTSDIDLALKDCDIAFLAVNTPSKTY 95


>UniRef50_Q7S3T1 Cluster: Putative uncharacterized protein
           NCU04936.1; n=4; Pezizomycotina|Rep: Putative
           uncharacterized protein NCU04936.1 - Neurospora crassa
          Length = 682

 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 37/62 (59%), Positives = 49/62 (79%)
 Frame = +1

Query: 268 IQKICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRE 447
           ++ ICC+GAGYVGGPT +VIA   P+I+VTV DK E+RI++WNS   PIYEPGL+ ++R 
Sbjct: 71  VRNICCVGAGYVGGPTAAVIAFNNPHIRVTVVDKDEKRIRRWNSVHPPIYEPGLNHILRI 130

Query: 448 CR 453
            R
Sbjct: 131 AR 132



 Score = 32.7 bits (71), Expect = 6.2
 Identities = 15/31 (48%), Positives = 21/31 (67%)
 Frame = +1

Query: 451 RGKNLFFSTNIAESIREAD*YLYPLTRPTKT 543
           R  NLFF+ ++A+SI EAD  L  +  PTK+
Sbjct: 183 RQPNLFFTADVAKSISEADIVLIAVNTPTKS 213


>UniRef50_UPI0001509F86 Cluster: UDP-glucose/GDP-mannose dehydrogenase
            family, NAD binding domain containing protein; n=2;
            Eukaryota|Rep: UDP-glucose/GDP-mannose dehydrogenase
            family, NAD binding domain containing protein -
            Tetrahymena thermophila SB210
          Length = 1559

 Score = 81.8 bits (193), Expect = 1e-14
 Identities = 38/91 (41%), Positives = 59/91 (64%), Gaps = 1/91 (1%)
 Frame = +1

Query: 271  QKICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQW-NSDKLPIYEPGLDDVVRE 447
            ++I C GAGYVGGPT +V A K P I+ T+ D  +++I++W  S+ LP++E GL  ++ E
Sbjct: 1088 ERISCFGAGYVGGPTMAVFASKHPQIQFTIYDIDKQQIEKWQQSETLPVFESGLSLLLEE 1147

Query: 448  CRGKNLFFSTNIAESIREAD*YLYPLTRPTK 540
             R KNL F+++I E++ E D     +  P K
Sbjct: 1148 TRNKNLSFTSDINEALDEVDIIFLAVNTPIK 1178


>UniRef50_Q7S3L5 Cluster: Putative uncharacterized protein
           NCU08228.1; n=2; Sordariales|Rep: Putative
           uncharacterized protein NCU08228.1 - Neurospora crassa
          Length = 665

 Score = 76.6 bits (180), Expect = 4e-13
 Identities = 47/115 (40%), Positives = 62/115 (53%), Gaps = 22/115 (19%)
 Frame = +1

Query: 268 IQKICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVR- 444
           ++ IC +GAG+VGGPT +VIA   P+I V V D +E+RI  WNS +LPI+E GL  VVR 
Sbjct: 105 VKSICFVGAGFVGGPTAAVIAYHNPDITVNVVDLNEQRIAAWNSSQLPIHEDGLLKVVRT 164

Query: 445 ---------------------ECRGKNLFFSTNIAESIREAD*YLYPLTRPTKTH 546
                                + R  NL FST + E+I  AD     +  PTKT+
Sbjct: 165 ARDGTVDTTVKIPGLPRSFKLDARSPNLVFSTKVNEAIEVADVIFICVNTPTKTY 219


>UniRef50_Q2UR48 Cluster: UDP-glucose/GDP-mannose dehydrogenase;
           n=4; Trichocomaceae|Rep: UDP-glucose/GDP-mannose
           dehydrogenase - Aspergillus oryzae
          Length = 655

 Score = 76.6 bits (180), Expect = 4e-13
 Identities = 45/112 (40%), Positives = 60/112 (53%), Gaps = 21/112 (18%)
 Frame = +1

Query: 271 QKICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVREC 450
           + +C +GAGYVGGPT +V+AL  P+I V V D+   RI++W S   P++EPGLD+VVR  
Sbjct: 86  KNVCVVGAGYVGGPTAAVLALHNPSIAVEVVDRDPRRIQRWKSRHPPVHEPGLDNVVRVA 145

Query: 451 RG---------------------KNLFFSTNIAESIREAD*YLYPLTRPTKT 543
           R                       NLFF+ + A SI  AD     +  PTKT
Sbjct: 146 RDGAEFVTASASIAAILGDAKRKPNLFFTCDSASSISRADMVFVAVNTPTKT 197


>UniRef50_A2QGJ1 Cluster: Contig An03c0120, complete genome.
           precursor; n=2; Aspergillus|Rep: Contig An03c0120,
           complete genome. precursor - Aspergillus niger
          Length = 646

 Score = 68.9 bits (161), Expect = 8e-11
 Identities = 32/82 (39%), Positives = 51/82 (62%), Gaps = 2/82 (2%)
 Frame = +1

Query: 268 IQKICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRE 447
           ++  C +GAG+VG  T  V+A + P+I+ +V D     I  WNSD+ P++EPGL+++ + 
Sbjct: 59  VRSACIIGAGHVGALTAVVLASQNPHIQFSVVDNDAGLINAWNSDRPPVFEPGLEEMFQP 118

Query: 448 CRGK--NLFFSTNIAESIREAD 507
            + K  NL FSTN+   +  AD
Sbjct: 119 RKRKLTNLTFSTNVHAGVAAAD 140


>UniRef50_A1C8W5 Cluster: UDP-glucose dehydrogenase Ugd1, putative;
           n=3; Trichocomaceae|Rep: UDP-glucose dehydrogenase Ugd1,
           putative - Aspergillus clavatus
          Length = 546

 Score = 59.7 bits (138), Expect = 5e-08
 Identities = 24/58 (41%), Positives = 38/58 (65%)
 Frame = +1

Query: 268 IQKICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVV 441
           ++  C +GAG+VG  T  ++A + P+++  + D     I  WNSD+LP+ EPGLDD+V
Sbjct: 59  VRNACIVGAGHVGALTGIILASQNPHVQFHIVDGESRLIAAWNSDRLPVLEPGLDDLV 116


>UniRef50_Q4FLP8 Cluster: UDPglucose 6-dehydrogenase; n=2;
           Candidatus Pelagibacter ubique|Rep: UDPglucose
           6-dehydrogenase - Pelagibacter ubique
          Length = 432

 Score = 53.6 bits (123), Expect = 3e-06
 Identities = 30/90 (33%), Positives = 48/90 (53%), Gaps = 1/90 (1%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDD-VVREC 450
           K+C +G GYVG    S +        V   DK   +I+   +  +PIYEPGL++ +++  
Sbjct: 2   KLCMIGTGYVG--LVSGVCFSDLGNDVICVDKDLNKIENLKNGIIPIYEPGLEELLIKNY 59

Query: 451 RGKNLFFSTNIAESIREAD*YLYPLTRPTK 540
           +   L FSTN+ +SI ++D     +  PTK
Sbjct: 60  KNNRLRFSTNLKDSISKSDIIFICVGTPTK 89


>UniRef50_Q6MAI0 Cluster: Probable UDPglucose 6-dehydrogenase; n=1;
           Candidatus Protochlamydia amoebophila UWE25|Rep:
           Probable UDPglucose 6-dehydrogenase - Protochlamydia
           amoebophila (strain UWE25)
          Length = 469

 Score = 53.2 bits (122), Expect = 4e-06
 Identities = 32/94 (34%), Positives = 49/94 (52%), Gaps = 1/94 (1%)
 Frame = +1

Query: 259 EMVIQKICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDV 438
           E     +  +G GYVG  T +  +       VT  D ++E+I+Q     +PIYEPGLD++
Sbjct: 6   ERTCMNLLIIGVGYVGLVTATCFSEM--GYYVTCLDINKEKIEQLKLGMIPIYEPGLDEM 63

Query: 439 V-RECRGKNLFFSTNIAESIREAD*YLYPLTRPT 537
           V R  + K L F+TN + S+  A+     +  PT
Sbjct: 64  VKRNIKSKRLTFTTNYSSSVPLANICFIAVDTPT 97


>UniRef50_Q191B5 Cluster: UDP-glucose/GDP-mannose dehydrogenase
           precursor; n=2; Desulfitobacterium hafniense|Rep:
           UDP-glucose/GDP-mannose dehydrogenase precursor -
           Desulfitobacterium hafniense (strain DCB-2)
          Length = 441

 Score = 52.8 bits (121), Expect = 5e-06
 Identities = 31/77 (40%), Positives = 50/77 (64%), Gaps = 2/77 (2%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVC-DKSEERIKQWNSDKLPIYEPGLDDVVR-E 447
           KIC +GAGYVG  + +++A    N+   VC D +E++I+   + KLPI+EPGL ++V   
Sbjct: 2   KICVVGAGYVGLVSAAILADWQHNV---VCVDHNEQKIEDLLAGKLPIFEPGLQELVELN 58

Query: 448 CRGKNLFFSTNIAESIR 498
            R + L F+  +AE++R
Sbjct: 59  RRRQYLRFTAEMAEALR 75


>UniRef50_Q5ARA8 Cluster: Putative uncharacterized protein; n=1;
           Emericella nidulans|Rep: Putative uncharacterized
           protein - Emericella nidulans (Aspergillus nidulans)
          Length = 514

 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 22/57 (38%), Positives = 35/57 (61%)
 Frame = +1

Query: 268 IQKICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDV 438
           ++++C +GAG  G  T  ++A   P ++  V D  EE I+ W SD LP  EPGL+++
Sbjct: 77  VRQVCIIGAGKEGVITGIILASHNPEVEFCVADTDEELIRLWKSDTLPFSEPGLENM 133


>UniRef50_O86422 Cluster: UDP-glucose 6-dehydrogenase; n=137;
           Bacteria|Rep: UDP-glucose 6-dehydrogenase - Pseudomonas
           aeruginosa
          Length = 453

 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 26/79 (32%), Positives = 48/79 (60%), Gaps = 1/79 (1%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVR-EC 450
           ++C +GAGYVG  T +  A +  N +V   ++  ER+ +    ++PIYEPGL+ ++R + 
Sbjct: 2   RLCVIGAGYVGLVTAACFA-EMGN-QVRCVERDRERVARLRRGEMPIYEPGLESILRDQL 59

Query: 451 RGKNLFFSTNIAESIREAD 507
               L F+ ++AE + +A+
Sbjct: 60  DAARLTFTASLAEGLADAE 78


>UniRef50_Q5KUU7 Cluster: NDP-suger dehydrogenase; n=15;
           Firmicutes|Rep: NDP-suger dehydrogenase - Geobacillus
           kaustophilus
          Length = 457

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 31/79 (39%), Positives = 49/79 (62%), Gaps = 1/79 (1%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVC-DKSEERIKQWNSDKLPIYEPGLDDVVREC 450
           KI   GAGYVG  T + +A K  ++   +C D +EE+I++ N   +PIYEPGL+ +++  
Sbjct: 2   KITIAGAGYVGLVTAACLADKGHDV---ICVDVNEEKIRRLNEGIVPIYEPGLEPLIQR- 57

Query: 451 RGKNLFFSTNIAESIREAD 507
               L F+T+ AE+ R A+
Sbjct: 58  NSARLRFTTDDAEAYRWAE 76


>UniRef50_A1S0Y4 Cluster: UDP-glucose 6-dehydrogenase; n=1;
           Thermofilum pendens Hrk 5|Rep: UDP-glucose
           6-dehydrogenase - Thermofilum pendens (strain Hrk 5)
          Length = 447

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 29/92 (31%), Positives = 49/92 (53%), Gaps = 1/92 (1%)
 Frame = +1

Query: 268 IQKICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRE 447
           + ++  +G GY G P    +AL     KV   D  EE+++  N    P+YEP L+D ++ 
Sbjct: 1   MDRVAVIGLGYAGLPFA--VALAHRGFKVVGVDTDEEKVELINKGVSPVYEPALNDYLKG 58

Query: 448 CRGKNLF-FSTNIAESIREAD*YLYPLTRPTK 540
              + LF  +T++A++I E+D     +  PTK
Sbjct: 59  VLERGLFKATTSVAKAIEESDVVFVFVGTPTK 90


>UniRef50_Q2W9U5 Cluster: Predicted UDP-glucose 6-dehydrogenase;
           n=4; Proteobacteria|Rep: Predicted UDP-glucose
           6-dehydrogenase - Magnetospirillum magneticum (strain
           AMB-1 / ATCC 700264)
          Length = 435

 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 29/90 (32%), Positives = 48/90 (53%), Gaps = 1/90 (1%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVV-REC 450
           +I  +G GYVG    S        I V   DK   +I++ + + +PIYEPGLDD+V    
Sbjct: 2   RIAMIGTGYVG--LVSGTCFSEFGIDVVCVDKDAAKIEKLHQNIMPIYEPGLDDMVAANV 59

Query: 451 RGKNLFFSTNIAESIREAD*YLYPLTRPTK 540
               L F+T++ E++++AD     +  P++
Sbjct: 60  EAGRLSFTTDLKEAVKDADAVFIAVGTPSR 89


>UniRef50_O32271 Cluster: UDP-glucose 6-dehydrogenase; n=5;
           Bacillus|Rep: UDP-glucose 6-dehydrogenase - Bacillus
           subtilis
          Length = 461

 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 30/81 (37%), Positives = 47/81 (58%), Gaps = 1/81 (1%)
 Frame = +1

Query: 268 IQKICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVV-R 444
           ++KI  +G GYVG  + +  A +  N KV  CD  E +I+   +  +PIYEPGL D+V +
Sbjct: 1   MKKIAVIGTGYVGLVSGTCFA-EIGN-KVVCCDIDESKIRSLKNGVIPIYEPGLADLVEK 58

Query: 445 ECRGKNLFFSTNIAESIREAD 507
               + L F+ +I  +IR +D
Sbjct: 59  NVLDQRLTFTNDIPSAIRASD 79


>UniRef50_Q7MVC7 Cluster: Sugar dehydrogenase,
           UDP-glucose/GDP-mannose dehydrogenase family; n=26;
           cellular organisms|Rep: Sugar dehydrogenase,
           UDP-glucose/GDP-mannose dehydrogenase family -
           Porphyromonas gingivalis (Bacteroides gingivalis)
          Length = 522

 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 28/78 (35%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
 Frame = +1

Query: 277 ICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVV-RECR 453
           I  +G GYVG  + +  A    N++    D++  +I+Q NS  +PIYEPGL+ ++ R  +
Sbjct: 81  IAVVGIGYVGLVSATCFAELGANVRCIDTDRN--KIEQLNSGTIPIYEPGLEKMIARNVK 138

Query: 454 GKNLFFSTNIAESIREAD 507
              L F T I +++ EAD
Sbjct: 139 AGRLRFGTEIEQAVPEAD 156


>UniRef50_O34862 Cluster: YtcA; n=5; Bacillaceae|Rep: YtcA -
           Bacillus subtilis
          Length = 428

 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 29/76 (38%), Positives = 41/76 (53%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRECR 453
           KIC +GAGYVG    + +A    ++  T  DK  ++I Q     +P YEPGL D +  C 
Sbjct: 2   KICVVGAGYVGLTLSAALASIGHDMICT--DKDVKKIGQLKKGVIPFYEPGLSDAILRC- 58

Query: 454 GKNLFFSTNIAESIRE 501
             NL FS+ +  S+ E
Sbjct: 59  -GNLSFSSEVKSSMEE 73


>UniRef50_Q5WD59 Cluster: UDP-glucose 6-dehydrogenase; n=1; Bacillus
           clausii KSM-K16|Rep: UDP-glucose 6-dehydrogenase -
           Bacillus clausii (strain KSM-K16)
          Length = 456

 Score = 50.0 bits (114), Expect = 4e-05
 Identities = 26/90 (28%), Positives = 49/90 (54%), Gaps = 1/90 (1%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVV-REC 450
           K+C +G GYVG    S +       +V   D+ +E+IK+ +  ++PI+EPGL+D++    
Sbjct: 2   KLCVIGTGYVG--LVSGVCYSHIGHEVVCVDRDQEKIKRLSQGEVPIFEPGLEDMLASNM 59

Query: 451 RGKNLFFSTNIAESIREAD*YLYPLTRPTK 540
               L F+T +++ +  AD  +  +  P +
Sbjct: 60  AAGRLSFTTRLSDGLAGADAAIIAVGTPAR 89


>UniRef50_Q8EMC5 Cluster: NDP-sugar dehydrogenase; n=2;
           Bacillaceae|Rep: NDP-sugar dehydrogenase -
           Oceanobacillus iheyensis
          Length = 440

 Score = 49.6 bits (113), Expect = 5e-05
 Identities = 27/83 (32%), Positives = 46/83 (55%), Gaps = 1/83 (1%)
 Frame = +1

Query: 262 MVIQKICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVV 441
           M+   +  +G GYVG  T + +A K    +V   D  E R++Q N+   PIYE G+++++
Sbjct: 1   MIEMDVAVIGTGYVGLVTGACLAEK--GHRVHCIDIDESRVQQLNNAISPIYEEGIEELL 58

Query: 442 RE-CRGKNLFFSTNIAESIREAD 507
           +      NLFF+T+  E + + D
Sbjct: 59  KNGINNDNLFFTTDYKEGLHQKD 81


>UniRef50_Q2S4Z2 Cluster: UDP-glucose dehydrogenase; n=1;
           Salinibacter ruber DSM 13855|Rep: UDP-glucose
           dehydrogenase - Salinibacter ruber (strain DSM 13855)
          Length = 439

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 31/88 (35%), Positives = 46/88 (52%), Gaps = 1/88 (1%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRECR 453
           +I  +G GYVG  + +  A    +  VT  D  EE++ Q +S +LPIYEP L+      R
Sbjct: 6   EIAVIGTGYVGLVSGTCFAEMGHD--VTCVDIDEEKVAQLSSGELPIYEPDLEKYFERAR 63

Query: 454 GK-NLFFSTNIAESIREAD*YLYPLTRP 534
            +  L F+T++AE I  A    + L  P
Sbjct: 64  SEGRLHFTTDLAEGIDGAKVIFFALPTP 91


>UniRef50_A7HFB2 Cluster: UDP-glucose 6-dehydrogenase; n=4;
           Bacteria|Rep: UDP-glucose 6-dehydrogenase -
           Anaeromyxobacter sp. Fw109-5
          Length = 503

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 29/70 (41%), Positives = 37/70 (52%), Gaps = 1/70 (1%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVV-REC 450
           KIC +G GYVG    +   L      VT  D  EE+I      + PIYEPGLD++V R  
Sbjct: 2   KICVIGTGYVG--LVAGACLADSGHLVTCIDTDEEKIALLRRGRSPIYEPGLDELVERNV 59

Query: 451 RGKNLFFSTN 480
             + L FS+N
Sbjct: 60  AQRRLAFSSN 69


>UniRef50_A6Q2Z6 Cluster: UDP-glucose 6-dehydrogenase; n=3; cellular
           organisms|Rep: UDP-glucose 6-dehydrogenase -
           Nitratiruptor sp. (strain SB155-2)
          Length = 455

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 27/79 (34%), Positives = 50/79 (63%), Gaps = 1/79 (1%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRE-C 450
           ++  +G GYVG  T + +A +  N  + V D  EE+I++     +PIYEPGL+++V+E  
Sbjct: 2   RLSIIGTGYVGLVTGACMA-QMGNSVICV-DIDEEKIEKLKKGIIPIYEPGLEEIVKENF 59

Query: 451 RGKNLFFSTNIAESIREAD 507
           +   L F+T+I ++++ +D
Sbjct: 60  KIGTLHFTTDIKDALKRSD 78


>UniRef50_A2QSA3 Cluster: Catalytic activity: UDP-glucose + 2 NAD(+)
           + H(2)O <=> UDP-glucuronate + 2 NADH; n=1; Aspergillus
           niger|Rep: Catalytic activity: UDP-glucose + 2 NAD(+) +
           H(2)O <=> UDP-glucuronate + 2 NADH - Aspergillus niger
          Length = 456

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 19/47 (40%), Positives = 29/47 (61%)
 Frame = +1

Query: 307 GPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRE 447
           G     +A K P+++  V D+    I  WNSD +PI+EPGL+D++ E
Sbjct: 4   GQLSEALASKNPSVQFNVVDRDASLIAVWNSDHIPIFEPGLEDIIFE 50


>UniRef50_Q0CCH6 Cluster: Predicted protein; n=1; Aspergillus
           terreus NIH2624|Rep: Predicted protein - Aspergillus
           terreus (strain NIH 2624)
          Length = 566

 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 23/56 (41%), Positives = 31/56 (55%)
 Frame = +1

Query: 280 CCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRE 447
           C +GA   G  T  V+A K P ++  V D     I  WNSD LPI EP L++++ E
Sbjct: 66  CIIGADGAGALTAIVLANKNPGVQFYVVDSDPRIIDAWNSDHLPISEPQLEELLFE 121


>UniRef50_Q11EL7 Cluster: UDP-glucose/GDP-mannose dehydrogenase;
           n=1; Mesorhizobium sp. BNC1|Rep: UDP-glucose/GDP-mannose
           dehydrogenase - Mesorhizobium sp. (strain BNC1)
          Length = 457

 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 29/86 (33%), Positives = 46/86 (53%), Gaps = 1/86 (1%)
 Frame = +1

Query: 286 LGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRE-CRGKN 462
           +GAGYVG  T + +A    N++    D +  RI +  +  +PIYEPGL + +R   +   
Sbjct: 6   IGAGYVGLTTGTCLANLGHNVRCFDIDAA--RIGRLQNFDIPIYEPGLQEAMRSAAKAGR 63

Query: 463 LFFSTNIAESIREAD*YLYPLTRPTK 540
           L FS  + ES+ +AD     +  P+K
Sbjct: 64  LSFSDQLRESVAQADAVFIAVGTPSK 89


>UniRef50_Q9RGJ9 Cluster: UDP-ManNAc dehydrogenase; n=15;
           Bacteria|Rep: UDP-ManNAc dehydrogenase - Bacteroides
           fragilis
          Length = 408

 Score = 46.0 bits (104), Expect = 6e-04
 Identities = 24/68 (35%), Positives = 39/68 (57%)
 Frame = +1

Query: 280 CCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRECRGK 459
           C +G GY+G PT ++IA K   +KVT  D + + ++  N  KL I EPG+ D++ E    
Sbjct: 4   CFMGLGYIGLPT-AIIAAK-HGVKVTGVDINPKVVEMTNEGKLHIIEPGMQDILEEVVAN 61

Query: 460 NLFFSTNI 483
            +  ++ I
Sbjct: 62  GMLTASTI 69


>UniRef50_Q2BE06 Cluster: Nucleotide sugar dehydrogenase; n=1;
           Bacillus sp. NRRL B-14911|Rep: Nucleotide sugar
           dehydrogenase - Bacillus sp. NRRL B-14911
          Length = 435

 Score = 46.0 bits (104), Expect = 6e-04
 Identities = 29/79 (36%), Positives = 47/79 (59%), Gaps = 1/79 (1%)
 Frame = +1

Query: 286 LGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRECR-GKN 462
           +GAGYVG  T SV   K  + KV V D+   +I     ++LP YE GL++  ++ +   N
Sbjct: 6   IGAGYVG-ITTSVAFAKYGH-KVFVMDQDPTKISMMKQNRLPFYEDGLENEFQQLQLNGN 63

Query: 463 LFFSTNIAESIREAD*YLY 519
           L F+ ++ E IR++D Y++
Sbjct: 64  LLFTGDLEECIRKSD-YIF 81


>UniRef50_Q67RC3 Cluster: UDP-glucose dehydrogenase; n=1;
           Symbiobacterium thermophilum|Rep: UDP-glucose
           dehydrogenase - Symbiobacterium thermophilum
          Length = 431

 Score = 45.6 bits (103), Expect = 8e-04
 Identities = 25/76 (32%), Positives = 42/76 (55%)
 Frame = +1

Query: 277 ICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRECRG 456
           I   GAGYVG  T + +       +V + +   ER+ +    + P YEPG+D ++R   G
Sbjct: 3   IAVAGAGYVGLTTAACLCEL--GHEVALLEIDGERVARLRRGECPFYEPGMDRLLRRHLG 60

Query: 457 KNLFFSTNIAESIREA 504
           ++L  +T++ E+IR A
Sbjct: 61  RSLTVTTSLDEAIRRA 76


>UniRef50_Q2NHK2 Cluster: Predicted UDP-N-acetyl-D-mannosaminuronate
           dehydrogenase; n=1; Methanosphaera stadtmanae DSM
           3091|Rep: Predicted UDP-N-acetyl-D-mannosaminuronate
           dehydrogenase - Methanosphaera stadtmanae (strain DSM
           3091)
          Length = 416

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 27/89 (30%), Positives = 44/89 (49%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRECR 453
           KIC +G GY+G PT ++ A       V   D +EE I   N+  + I EP +++++  C 
Sbjct: 2   KICVIGQGYIGIPTAALFASN--GCDVVGVDINEEIISNLNNGVMTIEEPKINEIMNACL 59

Query: 454 GKNLFFSTNIAESIREAD*YLYPLTRPTK 540
               + ++   E   EAD Y+  +  P K
Sbjct: 60  DNGTYHASLTPE---EADVYIITVPTPFK 85


>UniRef50_O26924 Cluster: UDP-N-acetyl-D-mannosaminuronic acid
           dehydrogenase; n=1; Methanothermobacter
           thermautotrophicus str. Delta H|Rep:
           UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase -
           Methanobacterium thermoautotrophicum
          Length = 431

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 23/62 (37%), Positives = 36/62 (58%)
 Frame = +1

Query: 271 QKICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVREC 450
           Q+I   G G++G PT ++ A      KVT  D + E +++ N  + P+ EPGLD++V E 
Sbjct: 4   QRIAVFGLGHIGLPTAALFARA--GFKVTGVDINPETVEKVNIGRSPVLEPGLDELVAEV 61

Query: 451 RG 456
            G
Sbjct: 62  VG 63


>UniRef50_A4FX80 Cluster: UDP-glucose 6-dehydrogenase; n=3;
           Methanococcus|Rep: UDP-glucose 6-dehydrogenase -
           Methanococcus maripaludis
          Length = 440

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 26/78 (33%), Positives = 42/78 (53%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRECR 453
           KI  +G GYVG        L     +V   D  E ++K  N    P++E GL++++R   
Sbjct: 2   KISVIGTGYVG--LIQATGLASFGFEVMGIDIDETKVKMLNEGLCPLHEEGLEELLRSHV 59

Query: 454 GKNLFFSTNIAESIREAD 507
           GKNL F+T+  E ++E++
Sbjct: 60  GKNLKFTTSY-ECLKESE 76


>UniRef50_O66443 Cluster: Nucleotide sugar dehydrogenase; n=11;
           Bacteria|Rep: Nucleotide sugar dehydrogenase - Aquifex
           aeolicus
          Length = 437

 Score = 44.8 bits (101), Expect = 0.001
 Identities = 27/75 (36%), Positives = 42/75 (56%), Gaps = 1/75 (1%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRE-C 450
           K+  +G GYVG  T +  +      +V V +K  E+++     K PIYEPGL++++RE  
Sbjct: 2   KLSVIGGGYVGLVTAACFSHL--GHEVLVVEKIPEKVELLRRGKSPIYEPGLEELLREGI 59

Query: 451 RGKNLFFSTNIAESI 495
               L F+T+I E I
Sbjct: 60  NEGRLSFTTDIKEGI 74


>UniRef50_Q84AP5 Cluster: UDP-N-acetyl-D-mannosaminuronic acid
           dehydrogenase; n=23; Gammaproteobacteria|Rep:
           UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase -
           Aeromonas hydrophila
          Length = 492

 Score = 44.8 bits (101), Expect = 0.001
 Identities = 23/62 (37%), Positives = 36/62 (58%)
 Frame = +1

Query: 262 MVIQKICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVV 441
           M  + I  +G GY+G PT +VIA     I+V   D ++  +   N  K+ I EPGL+D+V
Sbjct: 1   MKFETISVVGLGYIGLPTAAVIASN--GIRVIGVDVNQHAVDTINQGKIHIVEPGLEDLV 58

Query: 442 RE 447
           ++
Sbjct: 59  KQ 60


>UniRef50_Q81K29 Cluster: UDP-N-acetyl-D-mannosamine dehydrogenase;
           n=21; Bacillales|Rep: UDP-N-acetyl-D-mannosamine
           dehydrogenase - Bacillus anthracis
          Length = 427

 Score = 43.6 bits (98), Expect = 0.003
 Identities = 29/91 (31%), Positives = 49/91 (53%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRECR 453
           KIC +G GY+G PT ++ A      +V   D  ++ + + N+ ++ I EPGL +VV+E  
Sbjct: 2   KICTMGLGYIGLPTSAMFAKY--GTEVVGVDIHQKVVDKLNNGEIHIEEPGLGEVVKEVV 59

Query: 454 GKNLFFSTNIAESIREAD*YLYPLTRPTKTH 546
               F ++   E   EAD ++  ++ PT  H
Sbjct: 60  ANGKFRASLTPE---EADAFI--ISVPTPNH 85


>UniRef50_O29659 Cluster: UDP-glucose dehydrogenase; n=15;
           Euryarchaeota|Rep: UDP-glucose dehydrogenase -
           Archaeoglobus fulgidus
          Length = 465

 Score = 43.6 bits (98), Expect = 0.003
 Identities = 24/62 (38%), Positives = 36/62 (58%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRECR 453
           KI  LG+GYVG  T   I       ++   D  E +++  NS K PIYE GL++++++ R
Sbjct: 44  KIAILGSGYVGIVTG--IGFAELGHEIVFIDVDERKVEMLNSSKPPIYERGLEELMKKNR 101

Query: 454 GK 459
           GK
Sbjct: 102 GK 103


>UniRef50_Q2JWZ7 Cluster: UDP-glucose dehydrogenase; n=3;
           Cyanobacteria|Rep: UDP-glucose dehydrogenase -
           Synechococcus sp. (strain JA-3-3Ab) (Cyanobacteria
           bacteriumYellowstone A-Prime)
          Length = 472

 Score = 43.2 bits (97), Expect = 0.004
 Identities = 25/76 (32%), Positives = 45/76 (59%), Gaps = 2/76 (2%)
 Frame = +1

Query: 286 LGAGYVGGPTCSVIALKCPNIKVTVC-DKSEERIKQWNSDKLPIYEPGLDDVVRE-CRGK 459
           +GAGYVG  T + +A    ++   +C D +  +I+     +LPIYEPGL+++VRE     
Sbjct: 6   VGAGYVGLVTGACLAHLGHSV---ICIDNNPVKIENLQRGRLPIYEPGLEELVREGAEAG 62

Query: 460 NLFFSTNIAESIREAD 507
            L F+T++   ++ ++
Sbjct: 63  RLHFTTDLGLGVKASE 78


>UniRef50_Q2FTB3 Cluster: UDP-glucose 6-dehydrogenase; n=1;
           Methanospirillum hungatei JF-1|Rep: UDP-glucose
           6-dehydrogenase - Methanospirillum hungatei (strain JF-1
           / DSM 864)
          Length = 428

 Score = 42.7 bits (96), Expect = 0.006
 Identities = 27/83 (32%), Positives = 41/83 (49%)
 Frame = +1

Query: 259 EMVIQKICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDV 438
           E  I  I  +G GYVG  T S  A     +++   D  +  +   N    PIYE  L+D+
Sbjct: 2   ESTILNISVIGGGYVGLVTASCFAYLGHTVRIVEIDTKKAELI--NKGIPPIYEEKLEDI 59

Query: 439 VRECRGKNLFFSTNIAESIREAD 507
           +++  GKNL   ++  E I +AD
Sbjct: 60  LKQTSGKNLSAQSHY-EGIDDAD 81


>UniRef50_Q89GP9 Cluster: Blr6296 protein; n=4; Bacteria|Rep:
           Blr6296 protein - Bradyrhizobium japonicum
          Length = 420

 Score = 41.9 bits (94), Expect = 0.010
 Identities = 26/71 (36%), Positives = 36/71 (50%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRECR 453
           KI   G GYVG  T + +A      +V   D S+E++   N+   PI EPGLD++V    
Sbjct: 2   KIAVFGLGYVGMTTAACLARS--GHEVIGVDVSDEKVAIVNAGNSPITEPGLDELVARAV 59

Query: 454 GKNLFFSTNIA 486
            K L  +T  A
Sbjct: 60  RKGLLSATQNA 70


>UniRef50_Q1J352 Cluster: UDP-glucose 6-dehydrogenase; n=3; cellular
           organisms|Rep: UDP-glucose 6-dehydrogenase - Deinococcus
           geothermalis (strain DSM 11300)
          Length = 467

 Score = 41.9 bits (94), Expect = 0.010
 Identities = 26/78 (33%), Positives = 45/78 (57%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRECR 453
           ++  +G GYVG  T  ++A    N+ V V D  + ++      +LPIYEP LD ++R+  
Sbjct: 8   RVAVVGTGYVGLGTAVMLAYLGHNV-VGV-DVDQAKVDLLQRGQLPIYEPHLDQLLRDSA 65

Query: 454 GKNLFFSTNIAESIREAD 507
            + L ++T+ A +I +AD
Sbjct: 66  SR-LRWTTDYASAIPDAD 82


>UniRef50_Q98C77 Cluster: UDP-glucose dehydrogenase; n=4;
           Proteobacteria|Rep: UDP-glucose dehydrogenase -
           Rhizobium loti (Mesorhizobium loti)
          Length = 443

 Score = 41.5 bits (93), Expect = 0.013
 Identities = 24/74 (32%), Positives = 41/74 (55%), Gaps = 1/74 (1%)
 Frame = +1

Query: 289 GAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRECRGK-NL 465
           G GYVG    +V+A      +V   D  E ++++ N   +PI+EPGL+ +VRE      +
Sbjct: 7   GIGYVGLVQAAVLAEV--GHQVVCVDIDENKVERLNQGFVPIFEPGLESLVRENHAAGRI 64

Query: 466 FFSTNIAESIREAD 507
            F+T+ A ++R  +
Sbjct: 65  KFTTDAAAAVRHGE 78


>UniRef50_Q1QJ09 Cluster: UDP-glucose/GDP-mannose dehydrogenase;
           n=6; Proteobacteria|Rep: UDP-glucose/GDP-mannose
           dehydrogenase - Nitrobacter hamburgensis (strain X14 /
           DSM 10229)
          Length = 419

 Score = 41.5 bits (93), Expect = 0.013
 Identities = 22/60 (36%), Positives = 36/60 (60%)
 Frame = +1

Query: 268 IQKICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRE 447
           I+K+  +G GY+G PT +VIA +   +KV   D + + +K   S  + I EP LD +V++
Sbjct: 4   IKKVAVIGLGYIGLPTAAVIASR--GMKVVGIDTNPDIVKTVASGTIHIVEPDLDGLVQK 61


>UniRef50_Q58454 Cluster: Uncharacterized protein MJ1054 (EC
           1.1.1.-) [Contains: Mja UDPGD intein]; n=2;
           Methanococcales|Rep: Uncharacterized protein MJ1054 (EC
           1.1.1.-) [Contains: Mja UDPGD intein] - Methanococcus
           jannaschii
          Length = 895

 Score = 41.5 bits (93), Expect = 0.013
 Identities = 24/77 (31%), Positives = 41/77 (53%)
 Frame = +1

Query: 277 ICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRECRG 456
           I  +G GYVG      + L      V   D  E ++K  N  + P+YE GL+ ++++   
Sbjct: 3   ISVIGTGYVG--LIQAVGLAEFGFDVVGIDIDESKVKALNRGECPLYEEGLEGLLKKHVN 60

Query: 457 KNLFFSTNIAESIREAD 507
           KNL F+T+  + I+++D
Sbjct: 61  KNLTFTTSY-KPIKDSD 76


>UniRef50_Q02BK7 Cluster: UDP-glucose/GDP-mannose dehydrogenase;
           n=1; Solibacter usitatus Ellin6076|Rep:
           UDP-glucose/GDP-mannose dehydrogenase - Solibacter
           usitatus (strain Ellin6076)
          Length = 445

 Score = 41.1 bits (92), Expect = 0.018
 Identities = 26/91 (28%), Positives = 49/91 (53%), Gaps = 1/91 (1%)
 Frame = +1

Query: 271 QKICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRE- 447
           QKI  LG GYVG  T + +A      +VT  D+ + ++      + P +EPGL+++V + 
Sbjct: 19  QKIAVLGLGYVGCVTAACLARI--GHRVTGVDRDQFKVDSVLGGRAPFFEPGLEELVGDG 76

Query: 448 CRGKNLFFSTNIAESIREAD*YLYPLTRPTK 540
                L  + ++A+++ +AD  L  +  P++
Sbjct: 77  VATGRLSATVSLADAVADADVALICVGTPSE 107


>UniRef50_Q9UXJ6 Cluster: Udp-glucose dehydrogenase; n=2;
           Sulfolobaceae|Rep: Udp-glucose dehydrogenase -
           Sulfolobus solfataricus
          Length = 409

 Score = 41.1 bits (92), Expect = 0.018
 Identities = 26/88 (29%), Positives = 46/88 (52%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRECR 453
           +I  +G G VG  T +V+A +    +V   D  + ++K    ++ PIYEPGLD+++   +
Sbjct: 2   RIGVVGLGVVGLVTGAVLADQ--GHEVVGVDIDQNKVKGLQCNRSPIYEPGLDELL--LK 57

Query: 454 GKNLFFSTNIAESIREAD*YLYPLTRPT 537
            KN F  T    ++++ D     +  PT
Sbjct: 58  NKNRFLFTTDYSALKDVDIVFITVATPT 85


>UniRef50_Q8PXP4 Cluster: UDP-N-acetyl-D-mannosamine
           6-dehydrogenase; n=2; Methanomicrobia|Rep:
           UDP-N-acetyl-D-mannosamine 6-dehydrogenase -
           Methanosarcina mazei (Methanosarcina frisia)
          Length = 418

 Score = 40.7 bits (91), Expect = 0.023
 Identities = 26/89 (29%), Positives = 43/89 (48%)
 Frame = +1

Query: 268 IQKICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRE 447
           + KIC LG GY+G PT  + A      +V   D ++  +    + K+P  E G  +++  
Sbjct: 1   MSKICVLGQGYIGLPTALLFANN--GHEVVGIDVNKRVVDTLKAGKMPFEEKGFQELLDG 58

Query: 448 CRGKNLFFSTNIAESIREAD*YLYPLTRP 534
              KN F + ++ E   EAD +L  +  P
Sbjct: 59  AIAKNAFRAESLVE---EADTFLVAVPTP 84


>UniRef50_Q1IJZ4 Cluster: UDP-glucose 6-dehydrogenase precursor;
           n=2; Acidobacteria bacterium Ellin345|Rep: UDP-glucose
           6-dehydrogenase precursor - Acidobacteria bacterium
           (strain Ellin345)
          Length = 478

 Score = 40.3 bits (90), Expect = 0.031
 Identities = 23/78 (29%), Positives = 45/78 (57%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRECR 453
           KI  +G+GYVG  + +  A +  +  ++V D    ++    + ++PI+E  L +++ + R
Sbjct: 2   KIAVIGSGYVGLVSAACFA-EIGHEVISV-DNDHAKVNALRNGEVPIHEQFLPELLAKHR 59

Query: 454 GKNLFFSTNIAESIREAD 507
           GK L FST++ ++   AD
Sbjct: 60  GKGLKFSTSVGDATAWAD 77


>UniRef50_Q5UXR5 Cluster: UDP-glucose 6-dehydrogenase; n=4;
           Halobacteriaceae|Rep: UDP-glucose 6-dehydrogenase -
           Haloarcula marismortui (Halobacterium marismortui)
          Length = 435

 Score = 40.3 bits (90), Expect = 0.031
 Identities = 25/68 (36%), Positives = 36/68 (52%)
 Frame = +1

Query: 286 LGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRECRGKNL 465
           +G+GYVG  T     L     +V   D  E+ +   N+ + PI+EPGLD++V E  G  L
Sbjct: 6   VGSGYVG--TTVAACLADLGHEVVTIDIDEDIVDAINNGESPIHEPGLDELVAEHGGGRL 63

Query: 466 FFSTNIAE 489
             ST+  E
Sbjct: 64  RASTDYEE 71


>UniRef50_Q3IN79 Cluster: UDP-glucose 6-dehydrogenase 1; n=2;
           Halobacteriaceae|Rep: UDP-glucose 6-dehydrogenase 1 -
           Natronomonas pharaonis (strain DSM 2160 / ATCC 35678)
          Length = 455

 Score = 40.3 bits (90), Expect = 0.031
 Identities = 23/73 (31%), Positives = 39/73 (53%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRECR 453
           K+  +G+GYVG    + +A    N  V+  D  E  +   N    PI+EPGL+D++ +  
Sbjct: 2   KLNVVGSGYVGTTLAACLAEMGHN--VSAIDIDEATVAALNQGSAPIHEPGLEDLLADHV 59

Query: 454 GKNLFFSTNIAES 492
           G  L  +T+ A++
Sbjct: 60  GDRLQATTSYADA 72


>UniRef50_Q83D92 Cluster: UDP-glucose 6-dehydrogenase; n=4;
           Gammaproteobacteria|Rep: UDP-glucose 6-dehydrogenase -
           Coxiella burnetii
          Length = 449

 Score = 39.5 bits (88), Expect = 0.054
 Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVV-REC 450
           K+   GAGYVG    S + L      V  CD +EE+I +      PI+E  L+ ++ +  
Sbjct: 2   KVSVYGAGYVG--LVSAVCLAELGHSVCCCDVNEEKIAKLMQGITPIHEQQLEPLLQKNL 59

Query: 451 RGKNLFFSTNIAESIR 498
           + K +FF+T   E+++
Sbjct: 60  KIKRIFFTTRSDEAVK 75


>UniRef50_Q7NLQ9 Cluster: UDP-glucose dehydrogenase; n=19;
           Bacteria|Rep: UDP-glucose dehydrogenase - Gloeobacter
           violaceus
          Length = 463

 Score = 39.5 bits (88), Expect = 0.054
 Identities = 23/79 (29%), Positives = 41/79 (51%), Gaps = 1/79 (1%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVR-EC 450
           ++C +G GYVG  T + +A       V   D +  ++ Q  +   PI EPGL+ ++    
Sbjct: 2   RVCVIGTGYVGLVTGACLA--HIGHDVVGVDNNAAKVAQMQAGISPIVEPGLETIMTGAM 59

Query: 451 RGKNLFFSTNIAESIREAD 507
           + + L F+T+IA  +R  +
Sbjct: 60  QAQRLAFTTDIAAGVRHGE 78


>UniRef50_Q4UK39 Cluster: UDP-glucose 6-dehydrogenase; n=10;
           Rickettsia|Rep: UDP-glucose 6-dehydrogenase - Rickettsia
           felis (Rickettsia azadi)
          Length = 448

 Score = 39.5 bits (88), Expect = 0.054
 Identities = 28/89 (31%), Positives = 43/89 (48%), Gaps = 1/89 (1%)
 Frame = +1

Query: 277 ICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRECRG 456
           I  +G+GYVG    S I +      VT  D  E +I + N   LPIYE  LD+ +++   
Sbjct: 3   ITFIGSGYVG--LVSGIIMGYLGHNVTCLDNDEVKISKLNKQILPIYEAKLDEYLKQALE 60

Query: 457 KNLFFSTNIAES-IREAD*YLYPLTRPTK 540
            N    TNI  + ++ A+     +  P+K
Sbjct: 61  ANRLKFTNIYNNELQNAEAIFITVGTPSK 89


>UniRef50_O54068 Cluster: UDP-glucose 6-dehydrogenase; n=105;
           Bacteria|Rep: UDP-glucose 6-dehydrogenase - Rhizobium
           meliloti (Sinorhizobium meliloti)
          Length = 437

 Score = 39.5 bits (88), Expect = 0.054
 Identities = 26/90 (28%), Positives = 42/90 (46%), Gaps = 1/90 (1%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVV-REC 450
           KI  +GAGYVG    S +        V   DK E +I      ++PI+EPGLD +V    
Sbjct: 2   KITMIGAGYVG--LVSGVCFADFGHDVVCVDKDEGKISALKKGQIPIFEPGLDHLVASNV 59

Query: 451 RGKNLFFSTNIAESIREAD*YLYPLTRPTK 540
               L F+ ++  ++  +D     +  P++
Sbjct: 60  ASGRLNFTDDLKTAVAASDVVFIAVGTPSR 89


>UniRef50_A0V0Q2 Cluster: UDP-glucose 6-dehydrogenase precursor;
           n=2; cellular organisms|Rep: UDP-glucose 6-dehydrogenase
           precursor - Clostridium cellulolyticum H10
          Length = 424

 Score = 39.1 bits (87), Expect = 0.071
 Identities = 24/58 (41%), Positives = 34/58 (58%)
 Frame = +1

Query: 271 QKICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVR 444
           +KIC +G GY+G PT ++ A    +I V V D  EE +   N  K+ I EP LD +V+
Sbjct: 8   KKICIIGLGYIGLPTAAMFATHGHSI-VGV-DVKEEVVDSLNQGKIIIEEPYLDIMVQ 63


>UniRef50_A1R406 Cluster: UDP-glucose 6-dehydrogenase; n=1;
           Arthrobacter aurescens TC1|Rep: UDP-glucose
           6-dehydrogenase - Arthrobacter aurescens (strain TC1)
          Length = 461

 Score = 38.7 bits (86), Expect = 0.094
 Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 1/72 (1%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRECR 453
           KI  +G GY+G    + +A       V   D    +++Q N    P +EPGLD+++++ R
Sbjct: 2   KISVIGCGYLGAVHAATLASM--GHTVVGIDVDSSKVEQLNKAMAPFHEPGLDELLKDGR 59

Query: 454 GK-NLFFSTNIA 486
               L F+T+ A
Sbjct: 60  TTGRLVFTTDFA 71


>UniRef50_Q8U0F8 Cluster: NDP-sugar dehydrogenase; n=4;
           Thermococcaceae|Rep: NDP-sugar dehydrogenase -
           Pyrococcus furiosus
          Length = 434

 Score = 37.9 bits (84), Expect = 0.16
 Identities = 24/95 (25%), Positives = 47/95 (49%)
 Frame = +1

Query: 265 VIQKICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVR 444
           V  KI  +G GY+G PT  + A      +V   D  ++ + + NS K  I EPG+++ + 
Sbjct: 15  VRMKIAVIGLGYIGLPTAIMFAE--AGYEVIGFDVKKDVVDRINSGKAHIVEPGIEEKLN 72

Query: 445 ECRGKNLFFSTNIAESIREAD*YLYPLTRPTKTHR 549
           +   +    +T   E +R A+ ++  +  P + ++
Sbjct: 73  KVVKEERLKATTKVEKLRGANAFIICVQTPLEGNK 107


>UniRef50_Q56812 Cluster: UDP-glucose dehydrogenase; n=1;
           Xanthomonas campestris|Rep: UDP-glucose dehydrogenase -
           Xanthomonas campestris
          Length = 445

 Score = 37.5 bits (83), Expect = 0.22
 Identities = 24/80 (30%), Positives = 42/80 (52%), Gaps = 2/80 (2%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVC-DKSEERIKQWNSDKLPIYEPGLDDVVREC 450
           ++   G GYVG  T + +A    ++   +C D  + ++   N   +PIYEPGL+ +V+  
Sbjct: 2   RVAIFGTGYVGLVTGTCLAEVGHHV---ICVDIDQAKVDGLNRGVIPIYEPGLEPMVKGN 58

Query: 451 RGK-NLFFSTNIAESIREAD 507
                L F+T+ AE+I   +
Sbjct: 59  HASGRLRFTTDAAEAIAHGE 78


>UniRef50_Q4E8E3 Cluster: UDP-glucose 6-dehydrogenase; n=5;
           Wolbachia|Rep: UDP-glucose 6-dehydrogenase - Wolbachia
           endosymbiont of Drosophila simulans
          Length = 435

 Score = 37.5 bits (83), Expect = 0.22
 Identities = 20/53 (37%), Positives = 32/53 (60%)
 Frame = +1

Query: 277 ICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDD 435
           I  +G GYVG  +C++++ +  N  V   D + ++I+     K+PIYEPGL D
Sbjct: 3   ITIIGIGYVGLVSCAMLSEQGHN--VDCIDINTKKIELLKLGKIPIYEPGLAD 53


>UniRef50_Q5P7V5 Cluster: UDP-glucose dehydrogenase; n=12;
           Bacteria|Rep: UDP-glucose dehydrogenase - Azoarcus sp.
           (strain EbN1) (Aromatoleum aromaticum (strain EbN1))
          Length = 440

 Score = 37.1 bits (82), Expect = 0.29
 Identities = 25/76 (32%), Positives = 36/76 (47%), Gaps = 1/76 (1%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVV-REC 450
           KI  +G GYVG    S   L      V   D    +I+      +PI+EPGL ++V R  
Sbjct: 2   KITVVGTGYVG--LVSGACLADVGNDVLCLDVDPAKIRILKGGGIPIHEPGLLEIVRRNV 59

Query: 451 RGKNLFFSTNIAESIR 498
               LFF+T++  + R
Sbjct: 60  EAGRLFFTTDVERAAR 75


>UniRef50_Q07RH1 Cluster: UDP-glucose/GDP-mannose dehydrogenase;
           n=1; Rhodopseudomonas palustris BisA53|Rep:
           UDP-glucose/GDP-mannose dehydrogenase - Rhodopseudomonas
           palustris (strain BisA53)
          Length = 425

 Score = 37.1 bits (82), Expect = 0.29
 Identities = 14/42 (33%), Positives = 30/42 (71%)
 Frame = +1

Query: 364 DKSEERIKQWNSDKLPIYEPGLDDVVRECRGKNLFFSTNIAE 489
           D + + + +  + +LP++EPGLDD+VR+ +G+ L F++ + +
Sbjct: 31  DANTQLVAELKAGQLPVFEPGLDDLVRD-KGERLSFTSAVGD 71


>UniRef50_A3YS39 Cluster: UDP-glucose 6-dehydrogenase; n=2;
           Campylobacter jejuni|Rep: UDP-glucose 6-dehydrogenase -
           Campylobacter jejuni subsp. jejuni 260.94
          Length = 432

 Score = 36.7 bits (81), Expect = 0.38
 Identities = 24/78 (30%), Positives = 40/78 (51%), Gaps = 1/78 (1%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVV-REC 450
           K+  +G GYVG PT   + L      V   D+ + +I   N   L IYE  L+++  +  
Sbjct: 2   KVGIIGTGYVGLPT--GVGLAELGNDVICIDREKSKIDALNDGILTIYEDNLEELFHKNV 59

Query: 451 RGKNLFFSTNIAESIREA 504
           +   L F+T++ E I++A
Sbjct: 60  KEGRLKFTTSMQEGIKDA 77


>UniRef50_A1GFD3 Cluster: UDP-glucose 6-dehydrogenase; n=4;
           Actinomycetales|Rep: UDP-glucose 6-dehydrogenase -
           Salinispora arenicola CNS205
          Length = 471

 Score = 35.9 bits (79), Expect = 0.66
 Identities = 22/87 (25%), Positives = 39/87 (44%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRECR 453
           ++   GAGYVG  TC  +AL     +V   D   + ++   + +  + EPGL  +VR   
Sbjct: 32  RVVVAGAGYVG--TCLGVALAERGAEVVAVDSDPDTVEDLRAGRCRLPEPGLAPMVRRLA 89

Query: 454 GKNLFFSTNIAESIREAD*YLYPLTRP 534
                 ++   + ++ AD  L  +  P
Sbjct: 90  ATGRLTASTSFDPVQVADVVLVAVGTP 116


>UniRef50_A0JTU3 Cluster: UDP-glucose 6-dehydrogenase precursor;
           n=47; Actinobacteria (class)|Rep: UDP-glucose
           6-dehydrogenase precursor - Arthrobacter sp. (strain
           FB24)
          Length = 454

 Score = 35.1 bits (77), Expect = 1.2
 Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRECR 453
           KI  +G GY+G    + +A       V   D    +++Q      P +EPGLD+++R+ R
Sbjct: 2   KISVIGCGYLGAVHAATLASM--GHTVVGIDVDAAKVEQLARGFAPFFEPGLDELLRDGR 59

Query: 454 GK-NLFFSTNIA 486
               L FS + A
Sbjct: 60  ATGRLTFSADFA 71


>UniRef50_UPI000058904C Cluster: PREDICTED: hypothetical protein;
           n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 412

 Score = 34.7 bits (76), Expect = 1.5
 Identities = 17/59 (28%), Positives = 25/59 (42%)
 Frame = +1

Query: 259 EMVIQKICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDD 435
           E  I  +C +GAG VG      +    P  KV +    E   ++W S K  I+    D+
Sbjct: 2   EETIYDVCIIGAGMVGSAAAKWLCKLQPETKVCLIGPQEPTEEEWQSGKREIFSSHYDE 60


>UniRef50_Q4K1X3 Cluster: UDP-N-acetylmannosamine dehydrogenase
           MnaB; n=5; Bacteria|Rep: UDP-N-acetylmannosamine
           dehydrogenase MnaB - Streptococcus pneumoniae
          Length = 407

 Score = 34.7 bits (76), Expect = 1.5
 Identities = 17/69 (24%), Positives = 35/69 (50%)
 Frame = +1

Query: 286 LGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRECRGKNL 465
           +G GY+G PT  ++ L    +KV   D +++ ++  N  +    E GLD++  +     +
Sbjct: 5   IGLGYIGLPT--ILMLATNGVKVVGTDYNQDLVRTLNEGQTTFKEDGLDELFHKAVESGV 62

Query: 466 FFSTNIAES 492
            F+T   ++
Sbjct: 63  DFTTEYQQT 71


>UniRef50_Q57871 Cluster: Uncharacterized protein MJ0428; n=6;
           Methanococcales|Rep: Uncharacterized protein MJ0428 -
           Methanococcus jannaschii
          Length = 427

 Score = 34.7 bits (76), Expect = 1.5
 Identities = 15/40 (37%), Positives = 27/40 (67%)
 Frame = +1

Query: 271 QKICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQ 390
           ++IC +G GY+G PT S++A++     V   D +E+R+K+
Sbjct: 11  KRICVIGLGYIGLPTASMLAIQ--GFDVIGVDINEKRVKE 48


>UniRef50_A5UTQ6 Cluster: UDP-glucose/GDP-mannose dehydrogenase;
           n=3; Chloroflexi (class)|Rep: UDP-glucose/GDP-mannose
           dehydrogenase - Roseiflexus sp. RS-1
          Length = 470

 Score = 34.3 bits (75), Expect = 2.0
 Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLP-----IYEPGLDDV 438
           KI  +G G+VG    +V +      +V   D   +RI+ + S +       ++EPGL  +
Sbjct: 2   KIIVVGTGFVGLTHAAVCSEY--GHEVYAYDIDHQRIEAYRSCRPEAIEHYVHEPGLTSI 59

Query: 439 VRECRGKNLFFSTNIAESIREAD*YLYPLTRPTK 540
           + E  G+ LFF  ++   I  AD     L  P K
Sbjct: 60  ILENHGRYLFFVDDVESVIEGADALFLCLPTPPK 93


>UniRef50_Q9PCZ8 Cluster: UDP-glucose dehydrogenase; n=51; cellular
           organisms|Rep: UDP-glucose dehydrogenase - Xylella
           fastidiosa
          Length = 450

 Score = 33.9 bits (74), Expect = 2.7
 Identities = 21/73 (28%), Positives = 38/73 (52%), Gaps = 2/73 (2%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVR--E 447
           ++   G GYVG  T + +A      +V   D ++ ++   N   +PIYEPGL+ +V+   
Sbjct: 2   RVAIFGTGYVGLVTGTCLAEV--GHEVLCVDINQAKVDGLNCGVIPIYEPGLEPMVKANH 59

Query: 448 CRGKNLFFSTNIA 486
             G+  F + ++A
Sbjct: 60  ATGRLRFTTDSVA 72


>UniRef50_Q0AZ93 Cluster: UDP-glucose 6-dehydrogenase; n=1;
           Syntrophomonas wolfei subsp. wolfei str. Goettingen|Rep:
           UDP-glucose 6-dehydrogenase - Syntrophomonas wolfei
           subsp. wolfei (strain Goettingen)
          Length = 435

 Score = 33.9 bits (74), Expect = 2.7
 Identities = 19/70 (27%), Positives = 38/70 (54%), Gaps = 1/70 (1%)
 Frame = +1

Query: 268 IQKICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVVRE 447
           ++++  +G GY+G PT  ++A      +V   D+  + +++    K+ I EP L+ + ++
Sbjct: 20  VKQVIVMGLGYIGLPTAVILAAN--GYRVMGVDRDIKLLQELEQGKIHIEEPNLNLLFQQ 77

Query: 448 CRG-KNLFFS 474
            R  K L FS
Sbjct: 78  VRSEKKLRFS 87


>UniRef50_Q45410 Cluster: NDP-N-acetyl-D-galactosaminuronic acid
           dehydrogenase; n=80; Bacteria|Rep:
           NDP-N-acetyl-D-galactosaminuronic acid dehydrogenase -
           Ralstonia solanacearum (Pseudomonas solanacearum)
          Length = 423

 Score = 33.9 bits (74), Expect = 2.7
 Identities = 25/92 (27%), Positives = 44/92 (47%)
 Frame = +1

Query: 259 EMVIQKICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDV 438
           E+  + I  +G GY+G PT +V+A +    ++   D ++  +   N  ++ I EP LD +
Sbjct: 6   EIDFRTISVVGLGYIGLPTATVLASR--QRELIGVDINQHAVDTINQARIHIVEPDLDML 63

Query: 439 VRECRGKNLFFSTNIAESIREAD*YLYPLTRP 534
           VR    +    +T   E    AD +L  +  P
Sbjct: 64  VRAAVSQGYLRATTEPE---PADAFLIAVPTP 92


>UniRef50_Q89A08 Cluster: Putative uncharacterized protein; n=1;
           Clostridium tetani|Rep: Putative uncharacterized protein
           - Clostridium tetani
          Length = 117

 Score = 33.1 bits (72), Expect = 4.7
 Identities = 21/67 (31%), Positives = 35/67 (52%), Gaps = 4/67 (5%)
 Frame = -3

Query: 547 YGSSWGVLT--DININRLPECFR-RCSLRKINFYLYI-RGLHRLGQARKSVAYQSSIALS 380
           Y SS  +L   ++NIN LPE F+ +  +R I  Y  +    ++L    K +  Q  ++L+
Sbjct: 48  YKSSGNILDIEELNINNLPEEFKNKIEVRSIKIYNKVYNEFNKLCNQYKGIKKQDLLSLA 107

Query: 379 SLRFCRK 359
              FC+K
Sbjct: 108 LYEFCKK 114


>UniRef50_A6RSN0 Cluster: Putative uncharacterized protein; n=2;
           Sclerotiniaceae|Rep: Putative uncharacterized protein -
           Botryotinia fuckeliana B05.10
          Length = 540

 Score = 32.7 bits (71), Expect = 6.2
 Identities = 14/32 (43%), Positives = 20/32 (62%)
 Frame = +1

Query: 451 RGKNLFFSTNIAESIREAD*YLYPLTRPTKTH 546
           R  NLFFS N+ + + EAD  +  +  PTKT+
Sbjct: 73  RSPNLFFSDNVEKCLGEADLIMIAVNTPTKTY 104


>UniRef50_A6QYI2 Cluster: Predicted protein; n=1; Ajellomyces
           capsulatus NAm1|Rep: Predicted protein - Ajellomyces
           capsulatus NAm1
          Length = 1187

 Score = 32.7 bits (71), Expect = 6.2
 Identities = 16/56 (28%), Positives = 28/56 (50%)
 Frame = +1

Query: 274 KICCLGAGYVGGPTCSVIALKCPNIKVTVCDKSEERIKQWNSDKLPIYEPGLDDVV 441
           K+     GY+G P   +I + C   K+ +   SEE ++ W++D    Y+P L   +
Sbjct: 173 KMAGFRVGYLGDPENIIICISCRISKLAI---SEEAMQAWHADLCDSYKPTLQSAL 225


>UniRef50_Q0W3C1 Cluster: NDP-N-acetyl-D-galactosaminuronic acid
           dehydrogenase; n=8; Euryarchaeota|Rep:
           NDP-N-acetyl-D-galactosaminuronic acid dehydrogenase -
           Uncultured methanogenic archaeon RC-I
          Length = 493

 Score = 32.7 bits (71), Expect = 6.2
 Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 7/98 (7%)
 Frame = +1

Query: 268 IQKICCLGAGYVGGPTCSVIALKCPNIKVTV-----CDKSEERIKQWNSDKLPIY--EPG 426
           I+K+  +G GYVG P  ++ A  C   +  +        S  +I   N  + P+   EPG
Sbjct: 16  IRKVGVIGMGYVGIPAAALFA-DCRQFEHVLGFQRDSPSSGYKIDMLNRGESPLKGEEPG 74

Query: 427 LDDVVRECRGKNLFFSTNIAESIREAD*YLYPLTRPTK 540
           L+D++++   +  F  T     IRE D     +  P K
Sbjct: 75  LEDLLKKVVSEGRFECTPDFSRIRELDAVTLAIQTPFK 112


>UniRef50_A7P8X7 Cluster: Chromosome chr3 scaffold_8, whole genome
           shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
           chr3 scaffold_8, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 396

 Score = 32.3 bits (70), Expect = 8.1
 Identities = 14/57 (24%), Positives = 29/57 (50%)
 Frame = +1

Query: 394 NSDKLPIYEPGLDDVVRECRGKNLFFSTNIAESIREAD*YLYPLTRPTKTHR*WERR 564
           +S  LP Y P  ++V +  RG+ + +S    +S+ +    ++ L  P ++   W+ R
Sbjct: 336 DSSNLPYYAPTAEEVRKVMRGRRIIYSQETRKSLEKRSVMIFLLDLPRRSLIAWQER 392


>UniRef50_Q8N8W3 Cluster: CDNA FLJ38763 fis, clone KIDNE2014119;
           n=1; Homo sapiens|Rep: CDNA FLJ38763 fis, clone
           KIDNE2014119 - Homo sapiens (Human)
          Length = 261

 Score = 32.3 bits (70), Expect = 8.1
 Identities = 23/58 (39%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
 Frame = +1

Query: 382 IKQWNSDKLPIYEPGLDDVVRECRGKNLFFSTNIAESIREAD*YLYPL--TRPTKTHR 549
           I QWNS  L    P L  V  E R ++ FFS    +++ +AD  L PL  TRP +  R
Sbjct: 7   ILQWNSGYLQTDLPALQ-VFDEIRSESPFFSRARFQAVEQADLGLRPLPHTRPARPAR 63


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 565,666,614
Number of Sequences: 1657284
Number of extensions: 11214274
Number of successful extensions: 24595
Number of sequences better than 10.0: 83
Number of HSP's better than 10.0 without gapping: 24011
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 24567
length of database: 575,637,011
effective HSP length: 96
effective length of database: 416,537,747
effective search space used: 38321472724
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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