Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= NV021811
(712 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000DB72A4 Cluster: PREDICTED: similar to 3-phosphog... 120 5e-26
UniRef50_UPI00015B605A Cluster: PREDICTED: similar to GA19489-PA... 109 5e-23
UniRef50_A7SFV8 Cluster: Predicted protein; n=1; Nematostella ve... 99 9e-20
UniRef50_O43175 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 96 9e-19
UniRef50_Q2AHU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 93 8e-18
UniRef50_A5UQ03 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 91 3e-17
UniRef50_Q9X1C1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 90 4e-17
UniRef50_A2U4T1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 89 8e-17
UniRef50_Q8PW48 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 89 8e-17
UniRef50_Q3AQU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 89 1e-16
UniRef50_Q1IVI0 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 89 1e-16
UniRef50_A1SM51 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 88 2e-16
UniRef50_A1DFM4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 88 2e-16
UniRef50_Q0W4A2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 87 3e-16
UniRef50_Q58424 Cluster: D-3-phosphoglycerate dehydrogenase; n=7... 87 3e-16
UniRef50_Q3ZX05 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 87 4e-16
UniRef50_A7HDB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 87 4e-16
UniRef50_Q8YIU3 Cluster: D-3-PHOSPHOGLYCERATE DEHYDROGENASE; n=7... 86 9e-16
UniRef50_A6C9V4 Cluster: Phosphoglycerate dehydrogenase; n=1; Pl... 85 2e-15
UniRef50_P35136 Cluster: D-3-phosphoglycerate dehydrogenase; n=8... 84 3e-15
UniRef50_Q897N8 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 83 9e-15
UniRef50_A0LMX1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 82 1e-14
UniRef50_A0L7J1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 82 1e-14
UniRef50_Q8EN61 Cluster: Phosphoglycerate dehydrogenase; n=2; Ba... 81 2e-14
UniRef50_Q8UJZ6 Cluster: Phosphoglycerate dehydrogenase; n=3; Al... 80 6e-14
UniRef50_A6UQN3 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 80 6e-14
UniRef50_Q1PZY1 Cluster: Similar to D-3-phosphoglycerate dehydro... 79 1e-13
UniRef50_Q1AXS3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 79 1e-13
UniRef50_A3EWA5 Cluster: Phosphoglycerate dehydrogenase; n=2; Ba... 79 1e-13
UniRef50_Q7UQL2 Cluster: Phosphoglycerate dehydrogenase; n=2; Pl... 78 2e-13
UniRef50_O29445 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 78 2e-13
UniRef50_Q8TYK0 Cluster: Predicted dehydrogenase related to phos... 77 3e-13
UniRef50_O04130 Cluster: D-3-phosphoglycerate dehydrogenase, chl... 77 3e-13
UniRef50_Q67TJ9 Cluster: Phosphoglycerate dehydrogenase; n=1; Sy... 77 4e-13
UniRef50_P73821 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 77 4e-13
UniRef50_A7CYD6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 77 6e-13
UniRef50_UPI0000E4762C Cluster: PREDICTED: similar to D-3-phosph... 76 8e-13
UniRef50_A4YUP8 Cluster: Putative D-3-phosphoglycerate dehydroge... 76 8e-13
UniRef50_Q4L766 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 76 1e-12
UniRef50_UPI0000DC0E13 Cluster: 3-phosphoglycerate dehydrogenase... 74 3e-12
UniRef50_Q1NQ97 Cluster: D-isomer specific 2-hydroxyacid dehydro... 74 3e-12
UniRef50_Q8ZTC7 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 74 4e-12
UniRef50_O67741 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 73 7e-12
UniRef50_A4FIF2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 73 7e-12
UniRef50_A7P9P5 Cluster: Chromosome chr3 scaffold_8, whole genom... 73 7e-12
UniRef50_Q4WHR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 73 7e-12
UniRef50_A0V9Y4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 72 1e-11
UniRef50_O33116 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 72 1e-11
UniRef50_Q0EUV6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 72 2e-11
UniRef50_A1RDF9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 71 2e-11
UniRef50_A6PUG1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 71 3e-11
UniRef50_A0RW58 Cluster: Phosphoglycerate dehydrogenase; n=3; Cr... 71 4e-11
UniRef50_Q7D366 Cluster: AGR_pAT_578p; n=2; Agrobacterium tumefa... 70 5e-11
UniRef50_A4MA79 Cluster: D-isomer specific 2-hydroxyacid dehydro... 70 5e-11
UniRef50_Q8R716 Cluster: Phosphoglycerate dehydrogenase and rela... 70 7e-11
UniRef50_Q2LGV1 Cluster: Phosphoglycerate dehydrogenase; n=6; Ha... 69 9e-11
UniRef50_Q8EMJ8 Cluster: Hypothetical conserved protein; n=1; Oc... 69 1e-10
UniRef50_Q18XF4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 2e-10
UniRef50_A6C2G1 Cluster: Phosphoglycerate dehydrogenase; n=1; Pl... 69 2e-10
UniRef50_UPI00015BAF48 Cluster: D-isomer specific 2-hydroxyacid ... 68 2e-10
UniRef50_Q97N23 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 68 2e-10
UniRef50_A4ETV8 Cluster: Putative uncharacterized protein; n=6; ... 67 3e-10
UniRef50_Q6MN05 Cluster: Phosphoglycerate dehydrogenase; n=1; Bd... 66 8e-10
UniRef50_A6ULR7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 66 8e-10
UniRef50_A1IDH6 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 66 8e-10
UniRef50_Q3SK87 Cluster: D-isomer specific 2-hydroxyacid dehydro... 66 1e-09
UniRef50_A4FHH0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 66 1e-09
UniRef50_Q8XPB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 65 1e-09
UniRef50_Q9RUU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 65 2e-09
UniRef50_Q0FX01 Cluster: D-isomer specific 2-hydroxyacid dehydro... 65 2e-09
UniRef50_A7NGZ0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 65 2e-09
UniRef50_A7HM61 Cluster: Glyoxylate reductase; n=1; Fervidobacte... 65 2e-09
UniRef50_A5URV2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 65 2e-09
UniRef50_Q63VJ5 Cluster: D-3-phosphoglycerate dehydrogenase; n=8... 64 2e-09
UniRef50_Q5WLJ2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 64 2e-09
UniRef50_A0JVX0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 3e-09
UniRef50_Q0J5C2 Cluster: Os08g0447000 protein; n=11; Viridiplant... 64 3e-09
UniRef50_Q825H6 Cluster: Putative glycerate dehydrogenase; n=1; ... 64 4e-09
UniRef50_A4WXD4 Cluster: Dimethylmenaquinone methyltransferase; ... 64 4e-09
UniRef50_A6PPS4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 63 6e-09
UniRef50_A1HSQ7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 63 6e-09
UniRef50_A1AR04 Cluster: D-isomer specific 2-hydroxyacid dehydro... 63 6e-09
UniRef50_Q6W1I8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 63 7e-09
UniRef50_Q46VE6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 62 1e-08
UniRef50_A6Q7Q2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 62 1e-08
UniRef50_Q9WYG2 Cluster: Phosphoglycerate dehydrogenase, putativ... 62 1e-08
UniRef50_O50096 Cluster: Putative uncharacterized protein PH1388... 62 1e-08
UniRef50_Q8FPW0 Cluster: Putative uncharacterized protein; n=1; ... 62 2e-08
UniRef50_A7CY19 Cluster: D-isomer specific 2-hydroxyacid dehydro... 62 2e-08
UniRef50_UPI00015BD3AA Cluster: UPI00015BD3AA related cluster; n... 61 2e-08
UniRef50_O86322 Cluster: POSSIBLE D-3-PHOSPHOGLYCERATE DEHYDROGE... 61 2e-08
UniRef50_A6UCB8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 61 2e-08
UniRef50_A6CKS4 Cluster: Putative uncharacterized protein; n=1; ... 61 2e-08
UniRef50_A1W9A3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 61 2e-08
UniRef50_A0UAW1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 61 2e-08
UniRef50_UPI000050F9E4 Cluster: COG0111: Phosphoglycerate dehydr... 61 3e-08
UniRef50_A0LN07 Cluster: D-isomer specific 2-hydroxyacid dehydro... 61 3e-08
UniRef50_Q39LG4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 60 5e-08
UniRef50_A6G5P3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 60 7e-08
UniRef50_A4YFM2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 60 7e-08
UniRef50_Q3CIY1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 59 9e-08
UniRef50_A7HEG1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 59 9e-08
UniRef50_A3PPC6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 59 9e-08
UniRef50_P13443 Cluster: Glycerate dehydrogenase; n=15; Viridipl... 59 9e-08
UniRef50_Q7X388 Cluster: Phosphoglycerate dehydrogenase; n=3; Es... 59 1e-07
UniRef50_A7HBU0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 59 1e-07
UniRef50_Q97ZK1 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 59 1e-07
UniRef50_O28495 Cluster: 2-hydroxyacid dehydrogenase, putative; ... 59 1e-07
UniRef50_A6DQ00 Cluster: SerA; n=1; Lentisphaera araneosa HTCC21... 58 2e-07
UniRef50_Q7WM64 Cluster: Putative dehydrogenase; n=2; Bordetella... 58 2e-07
UniRef50_Q1K3M3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 58 2e-07
UniRef50_Q0K073 Cluster: D-3-Phosphoglycerate dehydrogenase; n=2... 58 2e-07
UniRef50_Q03WU1 Cluster: Lactate dehydrogenase related dehydroge... 58 2e-07
UniRef50_Q5KN70 Cluster: D-3-phosphoglycerate dehydrogenase 2, p... 58 2e-07
UniRef50_Q81T55 Cluster: D-isomer specific 2-hydroxyacid dehydro... 57 5e-07
UniRef50_Q3KBX8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 56 7e-07
UniRef50_Q8CPW2 Cluster: Glycerate dehydrogenase; n=4; Staphyloc... 56 9e-07
UniRef50_A0Z6W9 Cluster: Spermidine/putrescine ABC transporter A... 56 9e-07
UniRef50_Q8EP33 Cluster: Glycerate dehydrogenase; n=2; Bacillace... 56 1e-06
UniRef50_Q0ETU3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 56 1e-06
UniRef50_A5V6T9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 56 1e-06
UniRef50_A7P8C8 Cluster: Chromosome chr3 scaffold_8, whole genom... 56 1e-06
UniRef50_O58320 Cluster: Glyoxylate reductase; n=16; cellular or... 56 1e-06
UniRef50_Q7UQC8 Cluster: Probable 2-hydroxyacid dehydrogenase; n... 55 2e-06
UniRef50_Q21A61 Cluster: D-isomer specific 2-hydroxyacid dehydro... 55 2e-06
UniRef50_A3UGW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 55 2e-06
UniRef50_A2SRM1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 55 2e-06
UniRef50_Q1LCR9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 55 2e-06
UniRef50_Q031D4 Cluster: Phosphoglycerate dehydrogenase; n=20; S... 55 2e-06
UniRef50_A0VQR0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 55 2e-06
UniRef50_Q83AZ4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 3e-06
UniRef50_Q214B1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 3e-06
UniRef50_Q0W672 Cluster: Glycerate dehydrogenase; n=2; Archaea|R... 54 3e-06
UniRef50_P0A9T3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 54 3e-06
UniRef50_O34815 Cluster: YoaD; n=2; Bacillus|Rep: YoaD - Bacillu... 54 3e-06
UniRef50_Q3Y1E6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 3e-06
UniRef50_Q1FF19 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 3e-06
UniRef50_Q0FY56 Cluster: Putative phosphoglycerate dehydrogenase... 54 3e-06
UniRef50_Q01W77 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 3e-06
UniRef50_Q5KE95 Cluster: Phosphoglycerate dehydrogenase; n=2; Fi... 54 3e-06
UniRef50_Q6L245 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 54 3e-06
UniRef50_A0RUD3 Cluster: 2 lactate dehydrogenase; n=2; Thermopro... 54 3e-06
UniRef50_P40054 Cluster: D-3-phosphoglycerate dehydrogenase 1; n... 54 3e-06
UniRef50_Q72KT6 Cluster: Glycerate dehydrogenase/glyoxylate redu... 54 5e-06
UniRef50_A6GGA6 Cluster: Probable 2-hydroxyacid dehydrogenase; n... 54 5e-06
UniRef50_A6EBH4 Cluster: Phosphoglycerate dehydrogenase; n=1; Pe... 54 5e-06
UniRef50_Q5FUW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 53 6e-06
UniRef50_Q49ZM5 Cluster: Putative dehydrogenase; n=1; Staphyloco... 53 6e-06
UniRef50_A7IJ69 Cluster: D-isomer specific 2-hydroxyacid dehydro... 53 6e-06
UniRef50_Q8Y3L1 Cluster: Lmo2824 protein; n=14; Bacillales|Rep: ... 53 8e-06
UniRef50_Q88ZU6 Cluster: Phosphoglycerate dehydrogenase; n=2; La... 53 8e-06
UniRef50_Q6AMI7 Cluster: Related to D-3-phosphoglycerate dehydro... 53 8e-06
UniRef50_A1AQ02 Cluster: D-isomer specific 2-hydroxyacid dehydro... 53 8e-06
UniRef50_Q4WMF4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 53 8e-06
UniRef50_Q8TR50 Cluster: Glycerate dehydrogenase; n=2; Methanosa... 53 8e-06
UniRef50_Q88YI0 Cluster: Phosphoglycerate dehydrogenase; n=5; Ba... 52 1e-05
UniRef50_Q4AIL7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 1e-05
UniRef50_Q03YV3 Cluster: Lactate dehydrogenase related enzyme; n... 52 1e-05
UniRef50_A6T665 Cluster: Putative D-3-phosphoglycerate dehydroge... 52 1e-05
UniRef50_A1JTE6 Cluster: Putative oxidoreductase; n=1; Yersinia ... 52 1e-05
UniRef50_Q65WI5 Cluster: SerA protein; n=1; Mannheimia succinici... 52 1e-05
UniRef50_Q2S4U0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 1e-05
UniRef50_A6CRV0 Cluster: 2-hydroxyacid dehydrogenase; n=15; Baci... 52 1e-05
UniRef50_A3ZW64 Cluster: Phosphoglycerate dehydrogenase, putativ... 52 1e-05
UniRef50_A3K878 Cluster: 2-hydroxyacid dehydrogenase; n=1; Sagit... 52 1e-05
UniRef50_A0JWH0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 1e-05
UniRef50_A0GVM6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 1e-05
UniRef50_Q8R8Q2 Cluster: Lactate dehydrogenase and related dehyd... 52 2e-05
UniRef50_Q82U25 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 2e-05
UniRef50_Q5FUD9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 52 2e-05
UniRef50_Q30V14 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 2e-05
UniRef50_A6LZ51 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 2e-05
UniRef50_A4FK85 Cluster: D-3-phosphoglycerate dehydrogenase, put... 52 2e-05
UniRef50_A4AN91 Cluster: Predicted dehydrogenase; n=14; Bacteroi... 52 2e-05
UniRef50_A1RC54 Cluster: Glyoxylate reductase; n=2; Actinomyceta... 52 2e-05
UniRef50_Q6MY49 Cluster: NAD-dependant D-isomer specific 2-hydro... 52 2e-05
UniRef50_Q986P2 Cluster: Phosphoglycerate dehydrogenase; n=14; c... 51 2e-05
UniRef50_Q82XE1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 51 2e-05
UniRef50_Q7WEA3 Cluster: Phosphoglycerate dehydrogenase; n=1; Bo... 51 2e-05
UniRef50_Q74CK1 Cluster: Glycerate dehydrogenase; n=12; Bacteria... 51 2e-05
UniRef50_Q4IV69 Cluster: D-isomer specific 2-hydroxyacid dehydro... 51 2e-05
UniRef50_Q1WVK4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 51 2e-05
UniRef50_A4S3N1 Cluster: Predicted protein; n=2; Ostreococcus|Re... 51 2e-05
UniRef50_Q27SS3 Cluster: Glycerate dehydrogenase-like protein; n... 51 2e-05
UniRef50_Q9HVG5 Cluster: Glycerate dehydrogenase; n=23; Gammapro... 51 3e-05
UniRef50_Q896Z8 Cluster: 2-hydroxyacid dehydrogenase; n=4; Clost... 51 3e-05
UniRef50_Q6A5K9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 51 3e-05
UniRef50_A0HBX6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 51 3e-05
UniRef50_Q0CUD5 Cluster: Putative uncharacterized protein; n=1; ... 51 3e-05
UniRef50_A2QX18 Cluster: Contig An11c0250, complete genome; n=3;... 51 3e-05
UniRef50_Q9HK29 Cluster: 2-hydroxyacid dehydrogenase related pro... 51 3e-05
UniRef50_Q6F7L0 Cluster: Glycerate dehydrogenase; n=3; Gammaprot... 50 4e-05
UniRef50_Q3KAR6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 50 4e-05
UniRef50_Q0RXU8 Cluster: Phosphoglycerate dehydrogenase; n=1; Rh... 50 4e-05
UniRef50_A1W7V5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 50 4e-05
UniRef50_A4RX85 Cluster: Predicted protein; n=3; Ostreococcus|Re... 50 4e-05
UniRef50_Q27SN5 Cluster: Beta xylosidase-like protein; n=1; Acan... 50 4e-05
UniRef50_Q81N95 Cluster: D-3-phosphoglycerate dehydrogenase, put... 50 6e-05
UniRef50_A4FIJ9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 50 6e-05
UniRef50_A0Q8P3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 50 6e-05
UniRef50_Q5KQ73 Cluster: D-3-phosphoglycerate dehydrogenase, put... 50 6e-05
UniRef50_Q1MQK2 Cluster: Phosphoglycerate dehydrogenase and rela... 50 7e-05
UniRef50_Q0C254 Cluster: D-isomer specific 2-hydroxyacid dehydro... 50 7e-05
UniRef50_A1HMI9 Cluster: Phosphoglycerate dehydrogenase; n=1; Th... 50 7e-05
UniRef50_Q4IXK9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 49 1e-04
UniRef50_Q44NM9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 49 1e-04
UniRef50_A1HQU2 Cluster: Glyoxylate reductase; n=1; Thermosinus ... 49 1e-04
UniRef50_A1G3C5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 49 1e-04
UniRef50_A0ZEB8 Cluster: Predicted dehydrogenase; n=6; Cyanobact... 49 1e-04
UniRef50_A0QQ27 Cluster: Glyoxylate reductase; n=4; Mycobacteriu... 49 1e-04
UniRef50_Q9TXJ5 Cluster: D-3-phosphoglycerate dehydrogenase-like... 49 1e-04
UniRef50_A3H6F3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 49 1e-04
UniRef50_Q89QF5 Cluster: Blr3173 protein; n=3; Bradyrhizobium|Re... 49 1e-04
UniRef50_Q2LUG0 Cluster: 2-hydroxyacid dehydrogenase, D-isomer s... 49 1e-04
UniRef50_Q1GJ08 Cluster: D-isomer specific 2-hydroxyacid dehydro... 49 1e-04
UniRef50_Q125T3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 49 1e-04
UniRef50_Q03U10 Cluster: 2-hydroxyacid dehydrogenase; n=1; Lacto... 49 1e-04
UniRef50_A1HM37 Cluster: D-isomer specific 2-hydroxyacid dehydro... 49 1e-04
UniRef50_A0FZA8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 49 1e-04
UniRef50_A7EUN0 Cluster: Formate dehydrogenase; n=2; Sclerotinia... 49 1e-04
UniRef50_Q8F5N8 Cluster: Phosphoglycerate dehydrogenase; n=4; Le... 48 2e-04
UniRef50_Q6A895 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 48 2e-04
UniRef50_Q67M76 Cluster: Phosphoglycerate dehydrogenase, N-termi... 48 2e-04
UniRef50_Q3A6W9 Cluster: 3-phosphoglycerate dehydrogenase; n=1; ... 48 2e-04
UniRef50_Q11JF3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 48 2e-04
UniRef50_A1UEI9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 48 2e-04
UniRef50_A2A023 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 48 2e-04
UniRef50_UPI000023EBBC Cluster: hypothetical protein FG00146.1; ... 48 3e-04
UniRef50_Q6FCL4 Cluster: 2-keto-D-gluconate reductase; n=15; Pse... 48 3e-04
UniRef50_A0GDF1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 48 3e-04
UniRef50_Q5KFZ5 Cluster: Phosphoglycerate dehydrogenase, putativ... 48 3e-04
UniRef50_UPI000023F60F Cluster: hypothetical protein FG08018.1; ... 47 4e-04
UniRef50_Q5KYJ7 Cluster: Dehydrogenase; n=3; Firmicutes|Rep: Deh... 47 4e-04
UniRef50_Q5FKH9 Cluster: Glyoxylate reductase; n=1; Lactobacillu... 47 4e-04
UniRef50_A4A9T4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 47 4e-04
UniRef50_A3RV54 Cluster: 2-hydroxyacid dehydrogenase; n=5; Burkh... 47 4e-04
UniRef50_Q0CK41 Cluster: Putative uncharacterized protein; n=5; ... 47 4e-04
UniRef50_Q7WNI7 Cluster: Putative dehydrogenase; n=1; Bordetella... 47 5e-04
UniRef50_Q5LT44 Cluster: D-isomer specific 2-hydroxyacid dehydro... 47 5e-04
UniRef50_Q2S4S4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 47 5e-04
UniRef50_Q2NVC4 Cluster: Putative 2-hydroxyacid-family dehydroge... 47 5e-04
UniRef50_A4SWE6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 47 5e-04
UniRef50_Q3S8E5 Cluster: Putative D-isomer specific 2-hydroxyaci... 46 7e-04
UniRef50_Q11JH0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 7e-04
UniRef50_A7CR80 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 7e-04
UniRef50_A4R4W0 Cluster: Formate dehydrogenase; n=1; Magnaporthe... 46 7e-04
UniRef50_Q12VM6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 7e-04
UniRef50_Q9K7P7 Cluster: Glycerate dehydrogenase; n=8; Bacillace... 46 0.001
UniRef50_A5N5A9 Cluster: SerA; n=1; Clostridium kluyveri DSM 555... 46 0.001
UniRef50_A4EAR0 Cluster: Putative uncharacterized protein; n=1; ... 46 0.001
UniRef50_Q6CDS0 Cluster: Similar to tr|O94020 Candida albicans Y... 46 0.001
UniRef50_UPI0000DA2A77 Cluster: PREDICTED: similar to D-3-phosph... 46 0.001
UniRef50_Q89LI6 Cluster: Blr4558 protein; n=6; Bradyrhizobiaceae... 46 0.001
UniRef50_Q89J71 Cluster: 2-hydroxyacid dehydrogenase; n=8; Brady... 46 0.001
UniRef50_O94574 Cluster: Putative 2-hydroxyacid dehydrogenase C1... 46 0.001
UniRef50_Q97F10 Cluster: Possible phosphoglycerate dehydrogenase... 45 0.002
UniRef50_Q7NEV2 Cluster: Phosphoglycerate dehydrogenase; n=6; Ba... 45 0.002
UniRef50_Q3DL54 Cluster: Glyoxylate reductase, NADH-dependent; n... 45 0.002
UniRef50_Q0PQJ5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 45 0.002
UniRef50_A6C853 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 45 0.002
UniRef50_A5Z3X2 Cluster: Putative uncharacterized protein; n=1; ... 45 0.002
UniRef50_Q5V1E2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 45 0.002
UniRef50_Q89388 Cluster: A53R protein; n=3; Chlorovirus|Rep: A53... 45 0.002
UniRef50_Q7W397 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 45 0.002
UniRef50_Q4FNZ3 Cluster: Probable dehydrogenase; n=2; Candidatus... 45 0.002
UniRef50_Q126V3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 45 0.002
UniRef50_A7HWK6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 45 0.002
UniRef50_A4ARG6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 45 0.002
UniRef50_A0Y9Y1 Cluster: Glyoxylate reductase; n=2; unclassified... 45 0.002
UniRef50_A2F8V0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 45 0.002
UniRef50_Q752A0 Cluster: AFR675Wp; n=3; Saccharomycetales|Rep: A... 45 0.002
UniRef50_Q1CG62 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.003
UniRef50_Q12CS0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.003
UniRef50_Q120S8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.003
UniRef50_Q4PP80 Cluster: Putative glyoxylate reductase/hydroxypy... 44 0.003
UniRef50_Q8YEC6 Cluster: Gluconate 2-dehydrogenase; n=72; Alphap... 44 0.004
UniRef50_Q2JEY9 Cluster: Putative uncharacterized protein precur... 44 0.004
UniRef50_Q0FF66 Cluster: Glycolate reductase; n=2; Alphaproteoba... 44 0.004
UniRef50_A3IA61 Cluster: D-3 phosphoglycerate dehydrogenase; n=1... 44 0.004
UniRef50_A1S0J0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.004
UniRef50_P58220 Cluster: 2-ketogluconate reductase; n=75; Proteo... 44 0.004
UniRef50_UPI00015B49ED Cluster: PREDICTED: similar to putative g... 44 0.005
UniRef50_Q931A1 Cluster: Putative; n=2; Rhizobiales|Rep: Putativ... 44 0.005
UniRef50_Q8G427 Cluster: Possible 2-hydroxyacid dehydrogenase; n... 44 0.005
UniRef50_A1GFX2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.005
UniRef50_Q8EMJ4 Cluster: 2-ketogluconate reductase; n=1; Oceanob... 43 0.006
UniRef50_Q398N2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 43 0.006
UniRef50_Q2KZD5 Cluster: Putative reductase precursor; n=1; Bord... 43 0.006
UniRef50_Q0B1Q1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 43 0.006
UniRef50_A5G1C9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 43 0.006
UniRef50_A4BPX8 Cluster: Glycerate dehydrogenase; n=1; Nitrococc... 43 0.006
UniRef50_Q1E5G6 Cluster: Putative uncharacterized protein; n=1; ... 43 0.006
UniRef50_A4R1I1 Cluster: Putative uncharacterized protein; n=1; ... 43 0.006
UniRef50_Q1MPI0 Cluster: Lactate dehydrogenase and related dehyd... 43 0.009
UniRef50_Q1M6M5 Cluster: Putative glyoxylate reductase; n=1; Rhi... 43 0.009
UniRef50_Q0LSC3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 43 0.009
UniRef50_Q04DF1 Cluster: Lactate dehydrogenase related enzyme; n... 43 0.009
UniRef50_A5UPU9 Cluster: Glyoxylate reductase; n=12; Bacteria|Re... 43 0.009
UniRef50_A3JX80 Cluster: D-isomer specific 2-hydroxyacid dehydro... 43 0.009
UniRef50_Q7X9L3 Cluster: Formate dehydrogenase; n=4; Magnoliophy... 43 0.009
UniRef50_P17584 Cluster: D-2-hydroxyisocaproate dehydrogenase; n... 43 0.009
UniRef50_Q82XY9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.011
UniRef50_Q49UN3 Cluster: NAD-dependent formate dehydrogenase; n=... 42 0.011
UniRef50_Q397E0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.011
UniRef50_Q04AA8 Cluster: Lactate dehydrogenase related enzyme; n... 42 0.011
UniRef50_A5P5Y8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.011
UniRef50_Q2UDC2 Cluster: Glyoxylate/hydroxypyruvate reductase; n... 42 0.011
UniRef50_Q8YK31 Cluster: Glycerate dehydrogenase; n=3; Cyanobact... 42 0.015
UniRef50_Q7MV92 Cluster: Glycerate dehydrogenase; n=1; Porphyrom... 42 0.015
UniRef50_Q1GAM7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.015
UniRef50_A6DPW5 Cluster: 2-hydroxyacid-family dehydrogenase; n=2... 42 0.015
UniRef50_A0L0H4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.015
UniRef50_Q89F87 Cluster: Bll6814 protein; n=9; Bradyrhizobiaceae... 42 0.020
UniRef50_Q47W88 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.020
UniRef50_Q2RTD0 Cluster: Glycolate reductase; n=8; Alphaproteoba... 42 0.020
UniRef50_Q11QU3 Cluster: D-lactate dehydrogenase; n=1; Cytophaga... 42 0.020
UniRef50_A7FYM9 Cluster: D-lactate dehydrogenase; n=4; Clostridi... 42 0.020
UniRef50_Q8U6W5 Cluster: 2-hydroxyacid dehydrogenase; n=3; Alpha... 41 0.026
UniRef50_Q5LQR6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 41 0.026
UniRef50_A6FZB7 Cluster: Putative dehydrogenase; n=1; Plesiocyst... 41 0.026
UniRef50_A4SW26 Cluster: D-isomer specific 2-hydroxyacid dehydro... 41 0.026
UniRef50_Q9LE33 Cluster: T12C24.9; n=6; core eudicotyledons|Rep:... 41 0.026
UniRef50_Q5KKI9 Cluster: 2-hydroxyacid dehydrogenase, putative; ... 41 0.026
UniRef50_Q4P752 Cluster: Putative uncharacterized protein; n=1; ... 41 0.026
UniRef50_Q9UYH9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 41 0.026
UniRef50_A4TF35 Cluster: D-isomer specific 2-hydroxyacid dehydro... 41 0.035
UniRef50_A1WHT1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 41 0.035
UniRef50_A0Z2L3 Cluster: Putative uncharacterized protein; n=1; ... 41 0.035
UniRef50_O69054 Cluster: Phosphonate dehydrogenase; n=16; Bacter... 41 0.035
UniRef50_Q98GE4 Cluster: Phosphoglycerate dehydrogenase; n=5; Rh... 40 0.046
UniRef50_Q883D2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.046
UniRef50_Q11UL6 Cluster: Phosphoglycerate dehydrogenase; n=1; Cy... 40 0.046
UniRef50_Q0RPA4 Cluster: Putative D-isomer specific 2-hydroxyaci... 40 0.046
UniRef50_A7UH56 Cluster: Putative 2-hydroxy acid dehydrogenase; ... 40 0.046
UniRef50_A4QT80 Cluster: Putative uncharacterized protein; n=2; ... 40 0.046
UniRef50_O32264 Cluster: Probable 2-ketogluconate reductase; n=1... 40 0.046
UniRef50_Q59516 Cluster: Glycerate dehydrogenase; n=23; Proteoba... 40 0.046
UniRef50_Q39JN8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.060
UniRef50_A6W4F1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.060
UniRef50_A5G0Z0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.060
UniRef50_A0QVE9 Cluster: Glyoxylate reductase; n=1; Mycobacteriu... 40 0.060
UniRef50_Q8LL97 Cluster: Putative uncharacterized protein; n=1; ... 40 0.060
UniRef50_O75112 Cluster: LIM domain-binding protein 3; n=36; Eut... 40 0.060
UniRef50_Q120Q8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.080
UniRef50_Q0RXQ1 Cluster: Probable phosphoglycerate dehydrogenase... 40 0.080
UniRef50_A1BC99 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.080
UniRef50_A7S382 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 40 0.080
UniRef50_P36234 Cluster: Glycerate dehydrogenase; n=2; Hyphomicr... 40 0.080
UniRef50_Q7MT26 Cluster: D-isomer specific 2-hydroxyacid dehydro... 39 0.11
UniRef50_Q1VRN5 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 39 0.11
UniRef50_Q11AM6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 39 0.11
UniRef50_A5VE25 Cluster: D-isomer specific 2-hydroxyacid dehydro... 39 0.11
UniRef50_Q6BTY7 Cluster: Debaryomyces hansenii chromosome C of s... 39 0.11
UniRef50_Q98LH4 Cluster: Phosphoglycerate dehydrogenase; n=3; Me... 39 0.14
UniRef50_Q5WAF3 Cluster: 2-ketogluconate reductase; n=1; Bacillu... 39 0.14
UniRef50_Q5HW94 Cluster: D-isomer specific 2-hydroxyacid dehydro... 39 0.14
UniRef50_Q8GQX5 Cluster: 2-oxo-4-phenylbutanoate reductase; n=2;... 39 0.14
UniRef50_A5ZQ76 Cluster: Putative uncharacterized protein; n=2; ... 39 0.14
UniRef50_A4BI79 Cluster: D-lactate dehydrogenase; n=1; Reinekea ... 39 0.14
UniRef50_Q00TL2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 39 0.14
UniRef50_A5YST2 Cluster: Phosphoglycerate dehydrogenase; n=2; Ha... 39 0.14
UniRef50_UPI0000383A41 Cluster: COG1052: Lactate dehydrogenase a... 38 0.18
UniRef50_Q62LV8 Cluster: Glyoxylate reductase; n=53; cellular or... 38 0.18
UniRef50_Q5FTU6 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 38 0.18
UniRef50_A3ZMM2 Cluster: Dehydrogenase; n=1; Blastopirellula mar... 38 0.18
UniRef50_Q9C7T6 Cluster: Phosphoglycerate dehydrogenase, putativ... 38 0.18
UniRef50_Q8VX85 Cluster: Putative NAD-dependent formate dehydrog... 38 0.18
UniRef50_Q8ZXX8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 38 0.18
UniRef50_UPI0000E26021 Cluster: PREDICTED: hypothetical protein;... 38 0.24
UniRef50_Q98ST8 Cluster: Ff1c; n=6; Clupeocephala|Rep: Ff1c - Da... 38 0.24
UniRef50_A5N6P2 Cluster: GyaR; n=1; Clostridium kluyveri DSM 555... 38 0.24
UniRef50_A3VA29 Cluster: D-isomer specific 2-hydroxyacid dehydro... 38 0.24
UniRef50_Q8NIV8 Cluster: Putative uncharacterized protein B13H18... 38 0.24
UniRef50_Q4PER7 Cluster: Putative uncharacterized protein; n=1; ... 38 0.24
UniRef50_UPI000155367B Cluster: PREDICTED: hypothetical protein;... 38 0.32
UniRef50_Q8EMM3 Cluster: Dehydrogenase; n=2; cellular organisms|... 38 0.32
UniRef50_Q483F8 Cluster: Putative glyoxylate reductase; n=1; Col... 38 0.32
UniRef50_A7BQE7 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 38 0.32
UniRef50_A1ZGW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 38 0.32
UniRef50_A1WAF9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 38 0.32
UniRef50_A1K2N6 Cluster: Peptidoglycan-binding protein; n=1; Azo... 38 0.32
UniRef50_A0YEL9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 38 0.32
UniRef50_Q0D7C9 Cluster: Os07g0264100 protein; n=5; Oryza sativa... 38 0.32
UniRef50_Q55F22 Cluster: Putative uncharacterized protein; n=4; ... 38 0.32
UniRef50_Q1QXV7 Cluster: Erythronate-4-phosphate dehydrogenase; ... 38 0.32
UniRef50_UPI0000D9FBAD Cluster: PREDICTED: similar to 3-phosphog... 37 0.43
UniRef50_Q9L238 Cluster: Putative membrane protein; n=2; Strepto... 37 0.43
UniRef50_Q65DI9 Cluster: YoaD; n=1; Bacillus licheniformis ATCC ... 37 0.43
UniRef50_P73990 Cluster: D-isomer specific 2-hydroxyacid dehydro... 37 0.43
UniRef50_Q4PK14 Cluster: Predicted D-isomer specific 2-hydroxyac... 37 0.43
UniRef50_Q12E23 Cluster: D-isomer specific 2-hydroxyacid dehydro... 37 0.43
UniRef50_A1SPF8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 37 0.43
UniRef50_Q5K657 Cluster: Hydroxyacid dehydrogenase protein Ynl27... 37 0.43
UniRef50_Q2EG98 Cluster: Polycystic kidney disease 1-like 3 vari... 37 0.56
UniRef50_Q89EL0 Cluster: Blr7063 protein; n=1; Bradyrhizobium ja... 37 0.56
UniRef50_Q036G7 Cluster: Lactate dehydrogenase related 2-hydroxy... 37 0.56
UniRef50_A5MYX9 Cluster: Putative uncharacterized protein; n=1; ... 37 0.56
UniRef50_Q6NXD9 Cluster: SERTA domain containing 2; n=3; Clupeoc... 36 0.74
UniRef50_Q62LP5 Cluster: Putative uncharacterized protein; n=2; ... 36 0.74
UniRef50_Q2BHH2 Cluster: Glycerate dehydrogenase; n=1; Neptuniib... 36 0.74
UniRef50_Q1LFJ5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 36 0.74
UniRef50_Q023X8 Cluster: Putative uncharacterized protein; n=1; ... 36 0.74
UniRef50_A6CXX0 Cluster: Dehydrogenase; n=1; Vibrio shilonii AK1... 36 0.74
UniRef50_A4U158 Cluster: D-isomer specific 2-hydroxyacid dehydro... 36 0.74
UniRef50_A0NLL6 Cluster: Glycerate dehydrogenase; n=1; Stappia a... 36 0.74
UniRef50_Q8MR05 Cluster: LD48009p; n=11; Coelomata|Rep: LD48009p... 36 0.74
UniRef50_Q5KJK5 Cluster: Glycerate-and formate-dehydrogenase, pu... 36 0.74
UniRef50_A7I9X3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 36 0.74
UniRef50_UPI0000E499F2 Cluster: PREDICTED: similar to glutamate ... 36 0.98
UniRef50_Q579J7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 36 0.98
UniRef50_Q849D6 Cluster: Putative uncharacterized protein pSV2.1... 36 0.98
UniRef50_Q2B326 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 36 0.98
UniRef50_A7HB83 Cluster: Serine/threonine protein kinase; n=1; A... 36 0.98
UniRef50_A7AAD2 Cluster: Putative uncharacterized protein; n=1; ... 36 0.98
UniRef50_A6DBV6 Cluster: D-lactate dehydrogenase; n=1; Caminibac... 36 0.98
UniRef50_A5VEE7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 36 0.98
UniRef50_A1FGW0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 36 0.98
UniRef50_A6S7X7 Cluster: Predicted protein; n=1; Botryotinia fuc... 36 0.98
UniRef50_A6QZ02 Cluster: Predicted protein; n=2; Onygenales|Rep:... 36 0.98
UniRef50_Q47XK1 Cluster: Erythronate-4-phosphate dehydrogenase; ... 36 0.98
UniRef50_Q08911 Cluster: Formate dehydrogenase 1; n=71; Eukaryot... 36 0.98
UniRef50_Q5BU19 Cluster: Ribeye a protein; n=4; Clupeocephala|Re... 36 1.3
UniRef50_Q5U922 Cluster: (R)-2-hydroxyisocaproate dehydrogenase;... 36 1.3
UniRef50_Q1V300 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 36 1.3
UniRef50_A7MES0 Cluster: Putative uncharacterized protein; n=1; ... 36 1.3
UniRef50_A5P4J2 Cluster: LigA; n=1; Methylobacterium sp. 4-46|Re... 36 1.3
UniRef50_A4EQ78 Cluster: Dehydrogenase; n=1; Roseobacter sp. SK2... 36 1.3
UniRef50_Q9VAP9 Cluster: CG11873-PA; n=1; Drosophila melanogaste... 36 1.3
UniRef50_A6QVW0 Cluster: Putative uncharacterized protein; n=1; ... 36 1.3
UniRef50_Q59642 Cluster: D-lactate dehydrogenase; n=5; Pediococc... 36 1.3
UniRef50_Q81K70 Cluster: D-isomer specific 2-hydroxyacid dehydro... 35 1.7
UniRef50_A7CZQ9 Cluster: Putative uncharacterized protein; n=1; ... 35 1.7
UniRef50_A3JTB6 Cluster: Putative D-isomer specific 2-hydroxyaci... 35 1.7
UniRef50_A0PVI8 Cluster: D-3-phosphoglycerate dehydrogenase SerA... 35 1.7
UniRef50_Q54XA2 Cluster: Putative uncharacterized protein; n=1; ... 35 1.7
UniRef50_O77242 Cluster: Mucin-like protein; n=1; Heterodera gly... 35 1.7
UniRef50_Q6CFF2 Cluster: Yarrowia lipolytica chromosome B of str... 35 1.7
UniRef50_Q4PEQ2 Cluster: Putative uncharacterized protein; n=1; ... 35 1.7
UniRef50_Q6KZ29 Cluster: Gluconate 2-dehydrogenase; n=3; Archaea... 35 1.7
UniRef50_O14075 Cluster: Putative 2-hydroxyacid dehydrogenase UN... 35 1.7
UniRef50_UPI0000EBDD36 Cluster: PREDICTED: hypothetical protein;... 35 2.3
UniRef50_Q4SJ39 Cluster: Chromosome 21 SCAF14577, whole genome s... 35 2.3
UniRef50_Q73M93 Cluster: Glycerate dehydrogenase; n=3; Bacteria|... 35 2.3
UniRef50_Q5NR73 Cluster: 2-hydroxyacid dehydrogenase; n=1; Zymom... 35 2.3
UniRef50_Q0S7S0 Cluster: Probable phosphoglycerate dehydrogenase... 35 2.3
UniRef50_Q0FRD5 Cluster: Putative uncharacterized protein; n=1; ... 35 2.3
UniRef50_Q03XJ7 Cluster: 2-hydroxyacid dehydrogenase; n=3; Lacto... 35 2.3
UniRef50_A5V093 Cluster: D-isomer specific 2-hydroxyacid dehydro... 35 2.3
UniRef50_A5FIN4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 35 2.3
UniRef50_A1VTQ3 Cluster: Putative uncharacterized protein precur... 35 2.3
UniRef50_Q9LH95 Cluster: Arabidopsis thaliana genomic DNA, chrom... 35 2.3
UniRef50_Q5NAP7 Cluster: Putative uncharacterized protein P0417G... 35 2.3
UniRef50_A1D255 Cluster: Glycerate dehydrogenase; n=1; Neosartor... 35 2.3
UniRef50_A7D498 Cluster: D-isomer specific 2-hydroxyacid dehydro... 35 2.3
UniRef50_O60721 Cluster: Sodium/potassium/calcium exchanger 1 (N... 35 2.3
UniRef50_P56545 Cluster: C-terminal-binding protein 2; n=98; Coe... 35 2.3
UniRef50_UPI00015B4C72 Cluster: PREDICTED: similar to ENSANGP000... 34 3.0
UniRef50_UPI0000F2E851 Cluster: PREDICTED: hypothetical protein;... 34 3.0
UniRef50_UPI0000F2DE6B Cluster: PREDICTED: hypothetical protein;... 34 3.0
UniRef50_Q4RQ25 Cluster: Chromosome 17 SCAF15006, whole genome s... 34 3.0
UniRef50_Q8A5C0 Cluster: Putative uncharacterized protein; n=2; ... 34 3.0
UniRef50_Q7M7Q8 Cluster: PUTATIVE D-2-HYDROXYACID DEHYDROGENASE;... 34 3.0
UniRef50_Q64UR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 34 3.0
UniRef50_Q4JTY7 Cluster: Putative citrate lyase beta subunit; n=... 34 3.0
UniRef50_Q11SX0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 34 3.0
UniRef50_A7CWK1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 34 3.0
UniRef50_A4AG08 Cluster: Putative uncharacterized protein; n=1; ... 34 3.0
UniRef50_A3PDQ1 Cluster: Putative dehydrogenase; n=1; Prochloroc... 34 3.0
UniRef50_Q76KF6 Cluster: D-glycerate dehydrogenase; n=4; Entamoe... 34 3.0
UniRef50_Q4Q5E6 Cluster: RNA guanylyltransferase, putative; n=4;... 34 3.0
UniRef50_UPI0001553895 Cluster: PREDICTED: similar to C6orf205 p... 34 4.0
UniRef50_UPI0000EBC89F Cluster: PREDICTED: similar to Complement... 34 4.0
UniRef50_A7J7V2 Cluster: Putative uncharacterized protein N598R;... 34 4.0
UniRef50_Q8XN08 Cluster: D-lactate dehydrogenase; n=4; Firmicute... 34 4.0
UniRef50_Q7TVF9 Cluster: HYPOTHETICAL ALANINE AND PROLINE RICH P... 34 4.0
UniRef50_Q2SWA3 Cluster: Manganese/iron transporter, NRAMP famil... 34 4.0
UniRef50_A7D948 Cluster: Putative uncharacterized protein precur... 34 4.0
UniRef50_A6W9Y4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 34 4.0
UniRef50_A4MH20 Cluster: Lipoprotein, putative; n=33; Burkholder... 34 4.0
UniRef50_A4M784 Cluster: D-isomer specific 2-hydroxyacid dehydro... 34 4.0
UniRef50_A1GF52 Cluster: LigA precursor; n=1; Salinispora arenic... 34 4.0
UniRef50_Q5H9F3 Cluster: BCL6 corepressor-like protein 1; n=27; ... 34 4.0
UniRef50_A1C4V8 Cluster: Glycosyl hydrolase, family 18, putative... 34 4.0
UniRef50_Q6LYW5 Cluster: 2-hydroxyacid dehydrogenase, D-isomer s... 34 4.0
UniRef50_Q99ZM2 Cluster: D-lactate dehydrogenase; n=7; Streptoco... 34 4.0
UniRef50_UPI0000F1EF3F Cluster: PREDICTED: hypothetical protein;... 33 5.2
UniRef50_UPI0000EBE933 Cluster: PREDICTED: hypothetical protein;... 33 5.2
UniRef50_UPI00015A60B9 Cluster: UPI00015A60B9 related cluster; n... 33 5.2
UniRef50_UPI0000EB4AA8 Cluster: BCL6 co-repressor-like 1; n=3; A... 33 5.2
UniRef50_Q6NUX3 Cluster: Im:7137941 protein; n=3; Danio rerio|Re... 33 5.2
UniRef50_Q67M77 Cluster: Phosphoglycerate dehydrogenase, C-termi... 33 5.2
UniRef50_Q63YS2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 33 5.2
UniRef50_O66939 Cluster: D-lactate dehydrogenase; n=1; Aquifex a... 33 5.2
UniRef50_Q2CCV7 Cluster: Putative uncharacterized protein; n=1; ... 33 5.2
UniRef50_Q0RR16 Cluster: Putative tetR family transcriptional re... 33 5.2
UniRef50_A0U4F1 Cluster: Putative uncharacterized protein precur... 33 5.2
UniRef50_Q6JX09 Cluster: GlsA-related protein; n=2; Chlamydomona... 33 5.2
UniRef50_A5AZD0 Cluster: Putative uncharacterized protein; n=1; ... 33 5.2
UniRef50_Q20595 Cluster: Putative uncharacterized protein; n=3; ... 33 5.2
UniRef50_Q5KKJ8 Cluster: Glyoxylate reductase, putative; n=2; Fi... 33 5.2
>UniRef50_UPI0000DB72A4 Cluster: PREDICTED: similar to
3-phosphoglycerate dehydrogenase; n=1; Apis
mellifera|Rep: PREDICTED: similar to 3-phosphoglycerate
dehydrogenase - Apis mellifera
Length = 478
Score = 120 bits (288), Expect = 5e-26
Identities = 64/142 (45%), Positives = 83/142 (58%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNID+++A +KGV V+N PG N++SACELTC L+ LAR+V A +LK GRWDR LY+G
Sbjct: 80 DNIDLEAATRKGVIVLNTPGGNSISACELTCALISNLARNVTQAVQSLKDGRWDRKLYSG 139
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
EL+GKTLA+LG+G A ++S +A
Sbjct: 140 FELSGKTLAVLGMGRIGREVTRRMQAYGMRVIAFDPLLTSEDANYLNVEKFSLDEIWPMA 199
Query: 647 DYITLHTPLIESTRNFINARCL 712
DYIT+HTPLI T+N INA L
Sbjct: 200 DYITVHTPLIPQTKNLINATTL 221
Score = 67.7 bits (158), Expect = 3e-10
Identities = 33/62 (53%), Positives = 44/62 (70%)
Frame = +3
Query: 51 MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTK 230
M ++SVLI D V A C ELL +GI TTK K+SKE+L+ E+ NH+ L+VRS T+VT
Sbjct: 1 MSTTLRSVLISDPVDACCGELLVRHGIPVTTKYKLSKEKLIKELQNHEGLIVRSETKVTA 60
Query: 231 EV 236
+V
Sbjct: 61 DV 62
Score = 50.8 bits (116), Expect = 3e-05
Identities = 19/44 (43%), Positives = 29/44 (65%)
Frame = +1
Query: 508 RVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWP 639
R+GREV RM A+GM +I FDP ++++ + K L++IWP
Sbjct: 154 RIGREVTRRMQAYGMRVIAFDPLLTSEDANYLNVEKFSLDEIWP 197
>UniRef50_UPI00015B605A Cluster: PREDICTED: similar to GA19489-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA19489-PA - Nasonia vitripennis
Length = 511
Score = 109 bits (263), Expect = 5e-23
Identities = 57/142 (40%), Positives = 75/142 (52%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNID+ +A + G+ V+N PG N++SACELTC ++ LAR+VV A ++K GRWDR LY G
Sbjct: 80 DNIDIPAATRNGILVLNTPGGNSVSACELTCAVISALARNVVQAGQSMKEGRWDRKLYAG 139
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
EL+GK L ++G G A + A
Sbjct: 140 RELSGKALGVVGFGRIGREVAHRMKAFGMEIIAYDPFFTKEQAAQIGVTKGELEDIWKNA 199
Query: 647 DYITLHTPLIESTRNFINARCL 712
DYIT+HTPLI T+N INA L
Sbjct: 200 DYITVHTPLIPQTKNLINATTL 221
Score = 72.5 bits (170), Expect = 9e-12
Identities = 33/65 (50%), Positives = 48/65 (73%)
Frame = +3
Query: 51 MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTK 230
M V+++SVL+ D V +CA LL ++G+ TTK K+SKEEL+ E+ HD L+VRS T+VT
Sbjct: 1 MSVNLRSVLVSDPVDERCAALLTSHGVPVTTKYKLSKEELINELQKHDGLIVRSETKVTA 60
Query: 231 EVLDA 245
+V+ A
Sbjct: 61 DVIAA 65
Score = 62.1 bits (144), Expect = 1e-08
Identities = 28/46 (60%), Positives = 34/46 (73%)
Frame = +1
Query: 508 RVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPSS 645
R+GREVA RM AFGM II +DPF + +Q AQ TK ELEDIW ++
Sbjct: 154 RIGREVAHRMKAFGMEIIAYDPFFTKEQAAQIGVTKGELEDIWKNA 199
>UniRef50_A7SFV8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 487
Score = 99.1 bits (236), Expect = 9e-20
Identities = 56/142 (39%), Positives = 71/142 (50%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNID +A GV V+N PG N LSA E TC L+ LARH+ AS + K G+W+R + G
Sbjct: 81 DNIDTVAASLHGVLVMNTPGGNTLSAAEHTCALISSLARHIPQASASTKEGKWERKQFMG 140
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
+EL GKTLAI+GLG L A S LA
Sbjct: 141 NELFGKTLAIIGLGRIGREVALRMQSYGVKTIGYDPLVSPQDAAESNIEWMETEKIWPLA 200
Query: 647 DYITLHTPLIESTRNFINARCL 712
DYIT+H PLI T+ +N + +
Sbjct: 201 DYITVHVPLIPPTKGMLNDKTI 222
Score = 64.9 bits (151), Expect = 2e-09
Identities = 29/64 (45%), Positives = 44/64 (68%)
Frame = +3
Query: 57 VDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEV 236
+++K VLI D V + C +L G+ K+SKEEL+ EIP +D L+VRSAT+V+++V
Sbjct: 4 LELKRVLISDSVDSCCKTILERNGVTVDVNTKLSKEELVSEIPKYDGLIVRSATKVSEDV 63
Query: 237 LDAG 248
+ AG
Sbjct: 64 IKAG 67
>UniRef50_O43175 Cluster: D-3-phosphoglycerate dehydrogenase; n=53;
Bilateria|Rep: D-3-phosphoglycerate dehydrogenase - Homo
sapiens (Human)
Length = 533
Score = 95.9 bits (228), Expect = 9e-19
Identities = 49/138 (35%), Positives = 74/138 (53%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DN+D+++A +KG+ V+N P N+LSA ELTC +++ LAR + A+ ++K G+W+R + G
Sbjct: 81 DNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERKKFMG 140
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
+EL GKTL ILGLG + S + L
Sbjct: 141 TELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLPLEEIWPLC 200
Query: 647 DYITLHTPLIESTRNFIN 700
D+IT+HTPL+ ST +N
Sbjct: 201 DFITVHTPLLPSTTGLLN 218
Score = 58.4 bits (135), Expect = 2e-07
Identities = 24/44 (54%), Positives = 32/44 (72%)
Frame = +1
Query: 508 RVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWP 639
R+GREVATRM +FGM IG+DP +S + A F ++ LE+IWP
Sbjct: 155 RIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLPLEEIWP 198
Score = 53.6 bits (123), Expect = 5e-06
Identities = 25/65 (38%), Positives = 42/65 (64%)
Frame = +3
Query: 60 DIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 239
+++ VLI D + C ++L G+ K +SKEEL+ E+ + + L+VRSAT+VT +V+
Sbjct: 5 NLRKVLISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVI 64
Query: 240 DAGVK 254
+A K
Sbjct: 65 NAAEK 69
>UniRef50_Q2AHU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Halothermothrix orenii H 168|Rep: D-3-phosphoglycerate
dehydrogenase - Halothermothrix orenii H 168
Length = 527
Score = 92.7 bits (220), Expect = 8e-18
Identities = 50/138 (36%), Positives = 71/138 (51%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNID++ A K+G+ V N P N +SA E T +ML L+R++ A+ AL G WDR Y G
Sbjct: 75 DNIDIEEASKRGIIVFNTPTGNTISAVEHTIGMMLALSRNIPQANQALHEGIWDRKKYMG 134
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
E+ GKTL I+GLG +R + A P ++ +
Sbjct: 135 VEVKGKTLGIIGLGRIGSRVAVRAQAFGMKVIANDPYLPPEKAAKINVPLLGFKEVLKKS 194
Query: 647 DYITLHTPLIESTRNFIN 700
DYITLHTPL + T + ++
Sbjct: 195 DYITLHTPLTDETYHILS 212
Score = 39.9 bits (89), Expect = 0.060
Identities = 23/57 (40%), Positives = 31/57 (54%)
Frame = +3
Query: 72 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 242
VL+ D + K E+L T +S+EE L I +D L+VRS T+V KE LD
Sbjct: 4 VLVSDNISPKGIEILEQEA-DVTFNPDLSREEFLDIIGEYDGLIVRSMTEVDKEALD 59
>UniRef50_A5UQ03 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Chloroflexi (class)|Rep: D-3-phosphoglycerate
dehydrogenase - Roseiflexus sp. RS-1
Length = 524
Score = 90.6 bits (215), Expect = 3e-17
Identities = 50/142 (35%), Positives = 80/142 (56%), Gaps = 3/142 (2%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNID+++A ++G+ V+NAP +N+++ ELT L+L LARH+ A +++ AG+W+R + G
Sbjct: 75 DNIDLEAATRQGIMVVNAPASNSVAVAELTIALILSLARHIPQAHSSVVAGKWERNRFMG 134
Query: 467 SELAGKTLAILGLG---GSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFG 637
E+ KTL ++GLG AR G +++AP
Sbjct: 135 FEVRNKTLGLVGLGRIGAEVARRARGLEMHVVAYDPVVSTERAAQLGATLAPL---EEVL 191
Query: 638 LLADYITLHTPLIESTRNFINA 703
AD ++LH PLI++TRN I+A
Sbjct: 192 AQADIVSLHVPLIDATRNMIDA 213
Score = 40.3 bits (90), Expect = 0.046
Identities = 19/39 (48%), Positives = 27/39 (69%)
Frame = +3
Query: 144 KAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVK*R 260
+ + K L+ +P +DAL+VRSAT+VT EVL AG + R
Sbjct: 27 RTDLDKAGLIAILPEYDALIVRSATRVTAEVLAAGTRLR 65
Score = 38.3 bits (85), Expect = 0.18
Identities = 16/42 (38%), Positives = 25/42 (59%)
Frame = +1
Query: 508 RVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDI 633
R+G EVA R M+++ +DP VS ++ AQ T LE++
Sbjct: 149 RIGAEVARRARGLEMHVVAYDPVVSTERAAQLGATLAPLEEV 190
>UniRef50_Q9X1C1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Thermotogaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Thermotoga maritima
Length = 306
Score = 90.2 bits (214), Expect = 4e-17
Identities = 51/138 (36%), Positives = 67/138 (48%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNIDV A +KG+ V+N PGA+A S EL LML ARH+ A+ +LK G+W++ G
Sbjct: 78 DNIDVQKAKEKGIKVLNTPGASAPSVAELAMGLMLACARHIARATVSLKEGKWEKKALKG 137
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
EL GKTL ++G G P T +
Sbjct: 138 KELLGKTLGLIGFGNIGQEVAKRALAFGMKIIAYDPAKPETDLPVEYV---DLDTLFKES 194
Query: 647 DYITLHTPLIESTRNFIN 700
D+I+LH PL ESTR+ IN
Sbjct: 195 DFISLHVPLTESTRHIIN 212
Score = 41.5 bits (93), Expect = 0.020
Identities = 22/59 (37%), Positives = 34/59 (57%)
Frame = +3
Query: 72 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 248
V + D + + +LL T + K+EL+ IP D LVVRSAT+VT ++++AG
Sbjct: 6 VHVNDPLDKEATQLLMNKEELEVTSEHLEKDELMKIIPEVDVLVVRSATKVTADIIEAG 64
>UniRef50_A2U4T1 Cluster: D-3-phosphoglycerate dehydrogenase; n=14;
Bacillales|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus coagulans 36D1
Length = 541
Score = 89.4 bits (212), Expect = 8e-17
Identities = 49/138 (35%), Positives = 71/138 (51%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNIDVD+A +KG+ V+N+PG N +SA E T +ML L+R++ A + AG+W+R + G
Sbjct: 77 DNIDVDAATRKGIIVVNSPGGNTISATEHTLAMMLSLSRNIPQAHKSAAAGKWEREKFKG 136
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
EL KTL I+G G A + + A
Sbjct: 137 VELFKKTLGIIGTGKIGTEVAKRAKAFGMAVLGYDPYLTEERAAKLGIKKATLDEIAAQA 196
Query: 647 DYITLHTPLIESTRNFIN 700
D+ITLHTPL++ T++ IN
Sbjct: 197 DFITLHTPLMKETKHLIN 214
Score = 41.5 bits (93), Expect = 0.020
Identities = 16/42 (38%), Positives = 29/42 (69%)
Frame = +1
Query: 508 RVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDI 633
++G EVA R AFGM ++G+DP+++ ++ A+ K L++I
Sbjct: 151 KIGTEVAKRAKAFGMAVLGYDPYLTEERAAKLGIKKATLDEI 192
Score = 33.9 bits (74), Expect = 4.0
Identities = 18/60 (30%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
Frame = +3
Query: 69 SVLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 245
++L+ D V + + L A+ + I+ E+L I +D L+VR+ T+VTK++++A
Sbjct: 3 NILVTDKVSEEGLKKLYAHKDFIVEHQPGIAPEDLKATIGQYDGLIVRNQTKVTKDIIEA 62
>UniRef50_Q8PW48 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Methanomicrobia|Rep: D-3-phosphoglycerate dehydrogenase
- Methanosarcina mazei (Methanosarcina frisia)
Length = 540
Score = 89.4 bits (212), Expect = 8e-17
Identities = 49/138 (35%), Positives = 71/138 (51%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DN+DVD+A KKG+ V NAP N +SA E T +M+ ++R++ A+ +LKA W R + G
Sbjct: 91 DNVDVDAATKKGIIVANAPEGNMISAAEHTIAMMMSMSRNIPQANASLKAREWKRNKFMG 150
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
E+ GKTL ++GLG + A + A
Sbjct: 151 VEVKGKTLGVIGLGRIGSEVAKRAAGLEMNLMGYDPFISEKRAMELGVKLATVNEIAKEA 210
Query: 647 DYITLHTPLIESTRNFIN 700
DYIT+HTPLI+ TRN ++
Sbjct: 211 DYITVHTPLIKETRNILD 228
Score = 38.7 bits (86), Expect = 0.14
Identities = 21/63 (33%), Positives = 39/63 (61%)
Frame = +3
Query: 57 VDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEV 236
+D+K VL+ D + + E+L + + ++EL+ +I +DALV+RS TQVT+ +
Sbjct: 16 IDMK-VLVSDSLSNEGLEILKEH-FDIDVCTGLCEDELVEKIKGYDALVIRSGTQVTQRI 73
Query: 237 LDA 245
++A
Sbjct: 74 IEA 76
Score = 33.9 bits (74), Expect = 4.0
Identities = 13/25 (52%), Positives = 18/25 (72%)
Frame = +1
Query: 508 RVGREVATRMYAFGMNIIGFDPFVS 582
R+G EVA R MN++G+DPF+S
Sbjct: 165 RIGSEVAKRAAGLEMNLMGYDPFIS 189
>UniRef50_Q3AQU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Chlorobium/Pelodictyon group|Rep: D-3-phosphoglycerate
dehydrogenase - Chlorobium chlorochromatii (strain CaD3)
Length = 538
Score = 88.6 bits (210), Expect = 1e-16
Identities = 50/142 (35%), Positives = 71/142 (50%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNID+++A ++G+ V++ PG NA+SA E TC ++L ARH+ A LK G W++ LY G
Sbjct: 87 DNIDLEAATRQGIVVMSTPGGNAVSAAEHTCAMLLAAARHIPQAMADLKQGNWNKHLYAG 146
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
EL GKTL+++GLG + A L A
Sbjct: 147 IELEGKTLSLIGLGRVGREVAMRMQAFGMRTIAYDPAIADEDAALLDIELLPLHENLLRA 206
Query: 647 DYITLHTPLIESTRNFINARCL 712
D IT+H+ L EST N + L
Sbjct: 207 DVITIHSALDESTYNLLGKETL 228
Score = 46.8 bits (106), Expect = 5e-04
Identities = 24/60 (40%), Positives = 35/60 (58%)
Frame = +3
Query: 60 DIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 239
++ VLI D V +C LL +G T K +S +EL I +++ L+VRSAT + EVL
Sbjct: 11 NVMKVLITDSVHPQCGRLLLQHGFEVTEKPSLSPKELHAIIADYNILIVRSATSLPAEVL 70
Score = 39.1 bits (87), Expect = 0.11
Identities = 17/30 (56%), Positives = 21/30 (70%)
Frame = +1
Query: 508 RVGREVATRMYAFGMNIIGFDPFVSADQCA 597
RVGREVA RM AFGM I +DP ++ + A
Sbjct: 161 RVGREVAMRMQAFGMRTIAYDPAIADEDAA 190
>UniRef50_Q1IVI0 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Acidobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Acidobacteria bacterium (strain Ellin345)
Length = 531
Score = 88.6 bits (210), Expect = 1e-16
Identities = 55/145 (37%), Positives = 74/145 (51%), Gaps = 3/145 (2%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNI++++A +KG+ V+N PGANA++ E T LML LAR + A+ + AG+W++ G
Sbjct: 77 DNIELEAATRKGIAVMNTPGANAIAVAEHTIGLMLALARFIPRATETMHAGKWEKKSLQG 136
Query: 467 SELAGKTLAILGLGG---SAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFG 637
+EL GKTL I+GLG AR A +A R
Sbjct: 137 TELRGKTLGIVGLGRIGLEVARRAASFGMTLVAHDPYVSPAIAHDAKIRLADR---DEVL 193
Query: 638 LLADYITLHTPLIESTRNFINARCL 712
+ADYITLH L T N INA L
Sbjct: 194 AVADYITLHVGLTPQTANMINATTL 218
Score = 34.3 bits (75), Expect = 3.0
Identities = 18/41 (43%), Positives = 24/41 (58%)
Frame = +1
Query: 508 RVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELED 630
R+G EVA R +FGM ++ DP+VS A H K+ L D
Sbjct: 151 RIGLEVARRAASFGMTLVAHDPYVSP---AIAHDAKIRLAD 188
>UniRef50_A1SM51 Cluster: D-3-phosphoglycerate dehydrogenase; n=15;
Actinobacteria (class)|Rep: D-3-phosphoglycerate
dehydrogenase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 536
Score = 87.8 bits (208), Expect = 2e-16
Identities = 42/74 (56%), Positives = 52/74 (70%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DN+DV +A + GV V+NAP +N +SA EL LML ARH+ PA ALK G W RA YTG
Sbjct: 85 DNVDVRAATQAGVMVVNAPTSNIVSAAELAVALMLAAARHISPAHAALKNGEWKRARYTG 144
Query: 467 SELAGKTLAILGLG 508
+EL KT+ I+GLG
Sbjct: 145 TELYEKTVGIVGLG 158
Score = 39.5 bits (88), Expect = 0.080
Identities = 17/42 (40%), Positives = 27/42 (64%)
Frame = +1
Query: 508 RVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDI 633
R+G VA R+ AFGM I+ +DP+V A + AQ ++L+ +
Sbjct: 159 RIGVLVAQRLSAFGMKIVAYDPYVQAGRAAQMGVRLVDLDTL 200
>UniRef50_A1DFM4 Cluster: D-3-phosphoglycerate dehydrogenase; n=10;
Fungi/Metazoa group|Rep: D-3-phosphoglycerate
dehydrogenase - Neosartorya fischeri (strain ATCC 1020 /
DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain
ATCC 1020 / DSM 3700 / NRRL 181))
Length = 582
Score = 87.8 bits (208), Expect = 2e-16
Identities = 49/141 (34%), Positives = 78/141 (55%), Gaps = 3/141 (2%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DN+DV+ A K G+ V+N+P N +A E T L++ +AR++ A ++LK+G+W+R+ + G
Sbjct: 82 DNVDVEEATKLGIVVVNSPSGNIGAAAEHTIALLIAMARNIPEACSSLKSGKWERSKFVG 141
Query: 467 SELAGKTLAILGLGG---SAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFG 637
E+ GKTL+I+GLG + AR G A ++ S
Sbjct: 142 VEVKGKTLSIIGLGKVGLTVARLAKGLGMNVNALDPYASPAVAVSASVTLVSSLS--ELL 199
Query: 638 LLADYITLHTPLIESTRNFIN 700
AD++T+HTPLI ST+ I+
Sbjct: 200 PTADFLTIHTPLIASTKGMIS 220
Score = 33.9 bits (74), Expect = 4.0
Identities = 21/58 (36%), Positives = 32/58 (55%)
Frame = +3
Query: 72 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 245
VL+ + + LL A + + + +ELL IP ++ALVVRS T+VT +L A
Sbjct: 11 VLVPEKLSPDGLALLRA-SLEVDERRGLDADELLQIIPEYEALVVRSETKVTGNLLRA 67
>UniRef50_Q0W4A2 Cluster: D-3-phosphoglycerate dehydrogenase; n=11;
cellular organisms|Rep: D-3-phosphoglycerate
dehydrogenase - Uncultured methanogenic archaeon RC-I
Length = 526
Score = 87.4 bits (207), Expect = 3e-16
Identities = 46/138 (33%), Positives = 74/138 (53%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DN+DV +A +KG+ V NAP N ++ACE T ++ML ++R++ A+ +LK+G+W+R+ + G
Sbjct: 76 DNVDVPAATEKGIIVANAPEGNTIAACEHTLSMMLAMSRNIPQANASLKSGKWERSKFMG 135
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
E+ KTL I+GLG A A + A
Sbjct: 136 VEVMNKTLGIIGLGRIGGEITKRARSFGMEVLAYDPFTTAERAQQIGARLTTLDEIYEKA 195
Query: 647 DYITLHTPLIESTRNFIN 700
D+IT+HTPL ST++ ++
Sbjct: 196 DFITVHTPLTPSTKHMVS 213
Score = 48.4 bits (110), Expect = 2e-04
Identities = 22/60 (36%), Positives = 42/60 (70%), Gaps = 1/60 (1%)
Frame = +3
Query: 72 VLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 248
VL+ D + + ++L + G+ + +++KE+L+ +I +++AL++RS TQVTKEV+ AG
Sbjct: 3 VLVTDPISEEGIKILKSEPGVQVDIETRLTKEQLIEKIKDYNALIIRSETQVTKEVIAAG 62
Score = 38.3 bits (85), Expect = 0.18
Identities = 14/43 (32%), Positives = 26/43 (60%)
Frame = +1
Query: 508 RVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIW 636
R+G E+ R +FGM ++ +DPF +A++ Q L++I+
Sbjct: 150 RIGGEITKRARSFGMEVLAYDPFTTAERAQQIGARLTTLDEIY 192
>UniRef50_Q58424 Cluster: D-3-phosphoglycerate dehydrogenase; n=7;
Euryarchaeota|Rep: D-3-phosphoglycerate dehydrogenase -
Methanococcus jannaschii
Length = 524
Score = 87.4 bits (207), Expect = 3e-16
Identities = 52/138 (37%), Positives = 71/138 (51%), Gaps = 1/138 (0%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNIDV++A +KG+ V+NAP A+++S ELT LML AR++ A+ +LK G WDR + G
Sbjct: 75 DNIDVEAATEKGIIVVNAPDASSISVAELTMGLMLAAARNIPQATASLKRGEWDRKRFKG 134
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPS-SIAPRWSWRTFGLL 643
EL GKTL ++GLG + A S +
Sbjct: 135 IELYGKTLGVIGLGRIGQQVVKRAKAFGMNIIGYDPYIPKEVAESMGVELVDDINELCKR 194
Query: 644 ADYITLHTPLIESTRNFI 697
AD+ITLH PL TR+ I
Sbjct: 195 ADFITLHVPLTPKTRHII 212
Score = 39.5 bits (88), Expect = 0.080
Identities = 21/61 (34%), Positives = 35/61 (57%)
Frame = +3
Query: 72 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 251
+L+ D + ++L G ++KEELL +I + D LVVRS T+VT++V++
Sbjct: 4 ILVTDPLHEDAIKILEEVGEVEVATG-LTKEELLEKIKDADVLVVRSGTKVTRDVIEKAE 62
Query: 252 K 254
K
Sbjct: 63 K 63
Score = 38.3 bits (85), Expect = 0.18
Identities = 14/24 (58%), Positives = 20/24 (83%)
Frame = +1
Query: 508 RVGREVATRMYAFGMNIIGFDPFV 579
R+G++V R AFGMNIIG+DP++
Sbjct: 149 RIGQQVVKRAKAFGMNIIGYDPYI 172
>UniRef50_Q3ZX05 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Dehalococcoides|Rep: D-3-phosphoglycerate dehydrogenase
- Dehalococcoides sp. (strain CBDB1)
Length = 526
Score = 87.0 bits (206), Expect = 4e-16
Identities = 49/140 (35%), Positives = 68/140 (48%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNID+ +A G+ V+NAP N +SA E T LML +ARH+ A+ +LK+G+W R + G
Sbjct: 75 DNIDLKTATGNGIIVVNAPTGNTISATEHTLALMLAMARHIPRANASLKSGQWKRNEFVG 134
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
SEL GKTL I+GLG + A + A
Sbjct: 135 SELKGKTLGIVGLGNIGSEIAKRALALEMRVIGYDPFISMERAKKLQVELLPFEDLLKRA 194
Query: 647 DYITLHTPLIESTRNFINAR 706
D+ITLH P+ T+ I +
Sbjct: 195 DFITLHVPMTGQTKGLIGPK 214
Score = 41.1 bits (92), Expect = 0.026
Identities = 24/64 (37%), Positives = 35/64 (54%)
Frame = +3
Query: 63 IKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 242
+K VL+ D + A L K + EEL+ I +DAL+VRS TQVT ++++
Sbjct: 1 MKKVLVSDALSATGLAPLKEIA-QVDVKTGLKPEELISIIGEYDALLVRSQTQVTADIIN 59
Query: 243 AGVK 254
AG K
Sbjct: 60 AGKK 63
Score = 37.5 bits (83), Expect = 0.32
Identities = 14/41 (34%), Positives = 24/41 (58%)
Frame = +1
Query: 511 VGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDI 633
+G E+A R A M +IG+DPF+S ++ + + ED+
Sbjct: 150 IGSEIAKRALALEMRVIGYDPFISMERAKKLQVELLPFEDL 190
>UniRef50_A7HDB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Anaeromyxobacter sp. Fw109-5
Length = 528
Score = 87.0 bits (206), Expect = 4e-16
Identities = 43/142 (30%), Positives = 76/142 (53%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DN+D+ +A ++GV V+N PG ++++ EL +++L L+RHV A+ ++KAG+W++ + G
Sbjct: 77 DNVDLAAATRRGVVVMNTPGGSSITVAELALSMILALSRHVAAATGSVKAGKWEKKRFQG 136
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
ELAG+TL ++G+G + A A T A
Sbjct: 137 HELAGRTLGVVGIGNIGSVLVARAVALGMRVVAFDPFISAEAAAKLGASLVDLDTLWREA 196
Query: 647 DYITLHTPLIESTRNFINARCL 712
D +++H PL + TR+ ++A L
Sbjct: 197 DVVSIHVPLTDKTRHLVDATAL 218
Score = 40.7 bits (91), Expect = 0.035
Identities = 14/42 (33%), Positives = 26/42 (61%)
Frame = +1
Query: 511 VGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIW 636
+G + R A GM ++ FDPF+SA+ A+ + ++L+ +W
Sbjct: 152 IGSVLVARAVALGMRVVAFDPFISAEAAAKLGASLVDLDTLW 193
>UniRef50_Q8YIU3 Cluster: D-3-PHOSPHOGLYCERATE DEHYDROGENASE; n=75;
Bacteria|Rep: D-3-PHOSPHOGLYCERATE DEHYDROGENASE -
Brucella melitensis
Length = 538
Score = 85.8 bits (203), Expect = 9e-16
Identities = 45/142 (31%), Positives = 71/142 (50%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DN+D+ +A ++G+ V+N P N+++ E LM +AR + A T+ +AG+W++ + G
Sbjct: 84 DNVDIPAASRRGIIVMNTPFGNSITTAEHAIALMFAVARQLPEADTSTRAGKWEKNRFMG 143
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
E+ GKTL ++G G + A + A
Sbjct: 144 VEITGKTLGVVGCGNIGSIVATRGIGLKMHVVAFDPFLSDARAQELGVEKVELDELLARA 203
Query: 647 DYITLHTPLIESTRNFINARCL 712
D+ITLHTPLI+ TRN INA+ L
Sbjct: 204 DFITLHTPLIDKTRNIINAQTL 225
Score = 33.9 bits (74), Expect = 4.0
Identities = 14/41 (34%), Positives = 25/41 (60%)
Frame = +1
Query: 511 VGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDI 633
+G VATR M+++ FDPF+S + + K+EL+++
Sbjct: 159 IGSIVATRGIGLKMHVVAFDPFLSDARAQELGVEKVELDEL 199
>UniRef50_A6C9V4 Cluster: Phosphoglycerate dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: Phosphoglycerate
dehydrogenase - Planctomyces maris DSM 8797
Length = 541
Score = 84.6 bits (200), Expect = 2e-15
Identities = 52/142 (36%), Positives = 72/142 (50%), Gaps = 3/142 (2%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNID +A ++G+ V+N P N S E T LM+ LAR++ PA +K G+W+R TG
Sbjct: 77 DNIDRAAATREGIVVMNTPAGNTTSTAEQTIALMMALARNIGPAYATMKEGKWERKKLTG 136
Query: 467 SELAGKTLAILGLGG---SAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFG 637
+++AGKTLAI+GLG S A G A I
Sbjct: 137 TQVAGKTLAIIGLGRIGLSVAHRAQG--LEMKVIGYDPFMSAERAAEYGIELYKEVDELV 194
Query: 638 LLADYITLHTPLIESTRNFINA 703
D++T+HTPL + TR+ INA
Sbjct: 195 KHCDFLTVHTPLTDETRDLINA 216
Score = 36.3 bits (80), Expect = 0.74
Identities = 14/32 (43%), Positives = 22/32 (68%)
Frame = +1
Query: 508 RVGREVATRMYAFGMNIIGFDPFVSADQCAQF 603
R+G VA R M +IG+DPF+SA++ A++
Sbjct: 151 RIGLSVAHRAQGLEMKVIGYDPFMSAERAAEY 182
>UniRef50_P35136 Cluster: D-3-phosphoglycerate dehydrogenase; n=8;
Bacillaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus subtilis
Length = 525
Score = 84.2 bits (199), Expect = 3e-15
Identities = 49/138 (35%), Positives = 67/138 (48%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNID+D A K GV VINAP N +S E T ++ L RH+ A+ ++K+ W+R Y G
Sbjct: 74 DNIDIDEATKHGVIVINAPNGNTISTAEHTFAMISSLMRHIPQANISVKSREWNRTAYVG 133
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
SEL GKTL I+GLG + A ++ A
Sbjct: 134 SELYGKTLGIVGLGRIGSEIAQRRGAFGMTVHVFDPFLTEERAKKIGVNSRTFEEVLESA 193
Query: 647 DYITLHTPLIESTRNFIN 700
D IT+HTPL + T+ +N
Sbjct: 194 DIITVHTPLTKETKGLLN 211
Score = 36.3 bits (80), Expect = 0.74
Identities = 15/48 (31%), Positives = 27/48 (56%)
Frame = +1
Query: 508 RVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPSSGL 651
R+G E+A R AFGM + FDPF++ ++ + E++ S+ +
Sbjct: 148 RIGSEIAQRRGAFGMTVHVFDPFLTEERAKKIGVNSRTFEEVLESADI 195
>UniRef50_Q897N8 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Clostridiales|Rep: D-3-phosphoglycerate dehydrogenase -
Clostridium tetani
Length = 533
Score = 82.6 bits (195), Expect = 9e-15
Identities = 48/142 (33%), Positives = 70/142 (49%), Gaps = 2/142 (1%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNID+ A K+G+ V N P +N +SACELT L+L +R++ LK G WDR + G
Sbjct: 79 DNIDIPEATKRGIIVANTPDSNTISACELTIGLLLAQSRNIAKTDRFLKEGNWDRDSFMG 138
Query: 467 SELAGKTLAILGLG--GSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGL 640
+EL KTL I+GLG GS + ++ + +
Sbjct: 139 TELFNKTLGIIGLGRIGSLVATRMNAFDMKVIAYDPYISDERFKR-FNVEKKDTLEDLLK 197
Query: 641 LADYITLHTPLIESTRNFINAR 706
+D+IT+HTP E T N I+ +
Sbjct: 198 ESDFITIHTPRTEETINIISEK 219
Score = 42.3 bits (95), Expect = 0.011
Identities = 20/47 (42%), Positives = 31/47 (65%), Gaps = 1/47 (2%)
Frame = +1
Query: 508 RVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKME-LEDIWPSS 645
R+G VATRM AF M +I +DP++S ++ +F+ K + LED+ S
Sbjct: 153 RIGSLVATRMNAFDMKVIAYDPYISDERFKRFNVEKKDTLEDLLKES 199
Score = 39.1 bits (87), Expect = 0.11
Identities = 22/67 (32%), Positives = 36/67 (53%), Gaps = 1/67 (1%)
Frame = +3
Query: 57 VDIKSVLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKE 233
+D +LIVD + K ELL + K + +E+LL I N+D L++RS T + E
Sbjct: 1 MDKAKILIVDKIDTKGIELLESEPNFEVDIKMGLEREKLLNIIENYDGLIIRSDTNIDIE 60
Query: 234 VLDAGVK 254
+++ K
Sbjct: 61 LMNMAKK 67
>UniRef50_A0LMX1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep:
D-3-phosphoglycerate dehydrogenase - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 525
Score = 82.2 bits (194), Expect = 1e-14
Identities = 37/74 (50%), Positives = 52/74 (70%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNIDV +A +G V+N PGANA +A E T +ML LARH+ A+ +++ GRWD+ + G
Sbjct: 76 DNIDVKAASARGALVMNTPGANATAAAEHTIAMMLALARHIPQATQSMREGRWDKKRFMG 135
Query: 467 SELAGKTLAILGLG 508
+EL +TL I+GLG
Sbjct: 136 TELFHQTLGIIGLG 149
Score = 36.7 bits (81), Expect = 0.56
Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 1/58 (1%)
Frame = +3
Query: 72 VLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 242
VLI DG+ +L A GI + EE+ +P++DA++VRS T++T E+++
Sbjct: 3 VLICDGMHEVGLSILRAAEGIDVDVPDQPGAEEIKAMLPDYDAVIVRSRTRITAELIE 60
>UniRef50_A0L7J1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Magnetococcus sp. (strain MC-1)
Length = 527
Score = 82.2 bits (194), Expect = 1e-14
Identities = 46/142 (32%), Positives = 73/142 (51%), Gaps = 2/142 (1%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DN+D +A +KG+ V+N P NA++ EL TL + ARH+ A+ + KAG+W+++ + G
Sbjct: 76 DNVDTPAASQKGIIVMNTPFGNAITTAELGVTLAMAAARHIPAATASTKAGKWEKSRFMG 135
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGL-- 640
ELAGKT ++GL G+ R S+ + L
Sbjct: 136 RELAGKTAGVIGL-GNVGRLVAQRLAGLDMKVVAYDPFINKDRAISLGLEMVDKLEDLWP 194
Query: 641 LADYITLHTPLIESTRNFINAR 706
D +T+HTPL + TRN ++A+
Sbjct: 195 RVDLLTVHTPLNDHTRNLVDAK 216
Score = 39.1 bits (87), Expect = 0.11
Identities = 16/44 (36%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Frame = +1
Query: 511 VGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKME-LEDIWP 639
VGR VA R+ M ++ +DPF++ D+ ++ LED+WP
Sbjct: 151 VGRLVAQRLAGLDMKVVAYDPFINKDRAISLGLEMVDKLEDLWP 194
Score = 38.3 bits (85), Expect = 0.18
Identities = 19/58 (32%), Positives = 31/58 (53%)
Frame = +3
Query: 72 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 245
VLI D + E+ A G+ K +S +ELL I +D + +RSAT++ + + A
Sbjct: 4 VLIADKMSPMAEEVFRARGLEVDVKVGMSPDELLACIDQYDGIAIRSATRLPAQAIAA 61
>UniRef50_Q8EN61 Cluster: Phosphoglycerate dehydrogenase; n=2;
Bacillaceae|Rep: Phosphoglycerate dehydrogenase -
Oceanobacillus iheyensis
Length = 528
Score = 81.4 bits (192), Expect = 2e-14
Identities = 47/138 (34%), Positives = 68/138 (49%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNID+++A + GV V+NAP N SA E T +++ L+R++ A ALK +WDR + G
Sbjct: 78 DNIDLEAATENGVIVVNAPNGNTNSAAEHTMAMIMALSRNIPQAYHALKQKQWDRKRFVG 137
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
EL KTL I+GLG A A +
Sbjct: 138 VELKQKTLGIVGLGRIGAEVAARAKGQRMNVIAYDPFFTEEKAEQMGVQYGTLEDVLRAG 197
Query: 647 DYITLHTPLIESTRNFIN 700
D+IT+HTPL++ T++ IN
Sbjct: 198 DFITVHTPLLKETKHLIN 215
Score = 35.1 bits (77), Expect = 1.7
Identities = 16/42 (38%), Positives = 23/42 (54%)
Frame = +1
Query: 508 RVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDI 633
R+G EVA R MN+I +DPF + ++ Q LED+
Sbjct: 152 RIGAEVAARAKGQRMNVIAYDPFFTEEKAEQMGVQYGTLEDV 193
>UniRef50_Q8UJZ6 Cluster: Phosphoglycerate dehydrogenase; n=3;
Alphaproteobacteria|Rep: Phosphoglycerate dehydrogenase
- Agrobacterium tumefaciens (strain C58 / ATCC 33970)
Length = 354
Score = 79.8 bits (188), Expect = 6e-14
Identities = 34/77 (44%), Positives = 52/77 (67%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNIDVD+A ++ + V+ A GANALS E TL+ + + +VP + ++AGRW++A Y+G
Sbjct: 105 DNIDVDAASRREIPVVVAAGANALSVAEHAITLLFAVVKRIVPLDSGIRAGRWEKAGYSG 164
Query: 467 SELAGKTLAILGLGGSA 517
ELAG + ++G G A
Sbjct: 165 KELAGMIIGLVGFGAIA 181
>UniRef50_A6UQN3 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Methanococcus|Rep: D-3-phosphoglycerate dehydrogenase -
Methanococcus vannielii SB
Length = 523
Score = 79.8 bits (188), Expect = 6e-14
Identities = 37/74 (50%), Positives = 52/74 (70%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DN+D+D+A +KGV V+NAP A+++S EL LML AR++ A+ +LK G WDR + G
Sbjct: 75 DNVDLDAATEKGVVVVNAPDASSISVAELMFGLMLSAARNIPQATASLKKGEWDRKSFKG 134
Query: 467 SELAGKTLAILGLG 508
E+ KTL I+GLG
Sbjct: 135 MEVYAKTLGIVGLG 148
Score = 42.7 bits (96), Expect = 0.009
Identities = 25/58 (43%), Positives = 33/58 (56%)
Frame = +3
Query: 72 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 245
+LI D + E+L G IS EE+ +I + DALVVRS T VTKE++DA
Sbjct: 4 ILITDPLHESAIEILKEAGEVEIATG-ISIEEIKQKIKDADALVVRSGTTVTKEIIDA 60
Score = 35.9 bits (79), Expect = 0.98
Identities = 13/46 (28%), Positives = 28/46 (60%)
Frame = +1
Query: 508 RVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPSS 645
R+G++VA R AF MNI+ +DP++ + ++ + ++++ S
Sbjct: 149 RIGQQVAKRAQAFEMNIVAYDPYIPENVASELGIKLLSVDELCAES 194
>UniRef50_Q1PZY1 Cluster: Similar to D-3-phosphoglycerate
dehydrogenase; n=1; Candidatus Kuenenia
stuttgartiensis|Rep: Similar to D-3-phosphoglycerate
dehydrogenase - Candidatus Kuenenia stuttgartiensis
Length = 535
Score = 78.6 bits (185), Expect = 1e-13
Identities = 46/141 (32%), Positives = 69/141 (48%), Gaps = 1/141 (0%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNIDV +A KKG+ V+N P N +S E T L+ L+R V A ++K G+W++ +TG
Sbjct: 84 DNIDVPAATKKGIVVMNTPAGNIISTAEHTIALLCSLSRFVPQACASVKEGKWEKKKFTG 143
Query: 467 SELAGKTLAILGLGGSAAR-WPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLL 643
+L GKT I+GLG + + +I + R
Sbjct: 144 QQLTGKTFGIIGLGRVGRQVAKRAAALEMKVIGYDPFITTEISSQYNIHIVKNLRDLLAQ 203
Query: 644 ADYITLHTPLIESTRNFINAR 706
ADYIT+H L + T+N I ++
Sbjct: 204 ADYITIHVTLNKETKNLITSK 224
Score = 38.3 bits (85), Expect = 0.18
Identities = 15/33 (45%), Positives = 24/33 (72%)
Frame = +1
Query: 508 RVGREVATRMYAFGMNIIGFDPFVSADQCAQFH 606
RVGR+VA R A M +IG+DPF++ + +Q++
Sbjct: 158 RVGRQVAKRAAALEMKVIGYDPFITTEISSQYN 190
Score = 35.5 bits (78), Expect = 1.3
Identities = 21/61 (34%), Positives = 30/61 (49%)
Frame = +3
Query: 72 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 251
VLI D + C E+L G+ K + EL I D ++VRS T++T VL+
Sbjct: 12 VLIADDLPDVCNEILQNAGVEVLKKTGLKPPELDAVIKMCDGVIVRSNTKLTAPVLEKSE 71
Query: 252 K 254
K
Sbjct: 72 K 72
>UniRef50_Q1AXS3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Rubrobacter xylanophilus DSM 9941|Rep:
D-3-phosphoglycerate dehydrogenase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 527
Score = 78.6 bits (185), Expect = 1e-13
Identities = 41/86 (47%), Positives = 58/86 (67%), Gaps = 3/86 (3%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNID+++A K+G+ V NAP +N ++A E T LML +AR + A +L+ G W+RA + G
Sbjct: 74 DNIDIEAATKRGILVANAPESNTVAAAEHTLGLMLAVARRIPAADASLRRGEWNRAAFKG 133
Query: 467 SELAGKTLAILGLG--GS-AARWPLG 535
E+A KTL ++GLG GS AR LG
Sbjct: 134 VEVAEKTLGLVGLGHVGSIVARGALG 159
Score = 36.7 bits (81), Expect = 0.56
Identities = 22/58 (37%), Positives = 32/58 (55%)
Frame = +3
Query: 72 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 245
VL+ + + + ELL +S ELL I +D L+VRSAT+VT EV++A
Sbjct: 3 VLVTEKLAERGVELLRRE-FEVDVLLGLSPGELLERIGEYDGLIVRSATKVTAEVIEA 59
>UniRef50_A3EWA5 Cluster: Phosphoglycerate dehydrogenase; n=2;
Bacteria|Rep: Phosphoglycerate dehydrogenase -
Leptospirillum sp. Group II UBA
Length = 535
Score = 78.6 bits (185), Expect = 1e-13
Identities = 43/142 (30%), Positives = 71/142 (50%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DN+D+++A ++G+ V+N PG N ++ E T +L++ +AR + A+ + KAG+W+++ + G
Sbjct: 79 DNVDLEAATERGIVVMNTPGGNTVTTAEHTMSLLMSMARRIPQANASNKAGKWEKSKFMG 138
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
EL KTL I+G+G A S S A
Sbjct: 139 VELFQKTLGIVGMGKIGQHVAQIARGIAMNIIAFDPYLTPEVAEKSGVHPVSLDELFQRA 198
Query: 647 DYITLHTPLIESTRNFINARCL 712
D+IT+HTPL T IN + +
Sbjct: 199 DFITVHTPLTPETTGLINKQSI 220
Score = 46.8 bits (106), Expect = 5e-04
Identities = 24/63 (38%), Positives = 35/63 (55%)
Frame = +3
Query: 51 MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTK 230
M DI+ +LI D + + G K K+S +EL EI +D LV+RS T+VT+
Sbjct: 1 MSSDIR-ILISDAISEDGVRIFQKAGFHVDMKTKLSPQELAQEISQYDGLVIRSGTKVTR 59
Query: 231 EVL 239
E+L
Sbjct: 60 EIL 62
>UniRef50_Q7UQL2 Cluster: Phosphoglycerate dehydrogenase; n=2;
Planctomycetaceae|Rep: Phosphoglycerate dehydrogenase -
Rhodopirellula baltica
Length = 540
Score = 77.8 bits (183), Expect = 2e-13
Identities = 45/138 (32%), Positives = 68/138 (49%), Gaps = 1/138 (0%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNID +A ++G+ V+N P N +S E T ++L ++R++ A+ +L GRWDR + G
Sbjct: 77 DNIDKPAATRRGIVVMNTPAGNTVSTAEHTFAMLLAMSRNIAAANQSLVEGRWDRKKFMG 136
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGL-L 643
+++AGKTL I+G+G A S R + L
Sbjct: 137 TQVAGKTLGIVGMGRIGREVASRAQAFDMDVVAFDPFLTDDQAESLKVRRVATVDDMLPQ 196
Query: 644 ADYITLHTPLIESTRNFI 697
DY+T+HTPL TR I
Sbjct: 197 IDYLTVHTPLTPETRGLI 214
Score = 42.3 bits (95), Expect = 0.011
Identities = 18/45 (40%), Positives = 30/45 (66%), Gaps = 1/45 (2%)
Frame = +1
Query: 508 RVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKM-ELEDIWP 639
R+GREVA+R AF M+++ FDPF++ DQ ++ ++D+ P
Sbjct: 151 RIGREVASRAQAFDMDVVAFDPFLTDDQAESLKVRRVATVDDMLP 195
>UniRef50_O29445 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
cellular organisms|Rep: D-3-phosphoglycerate
dehydrogenase - Archaeoglobus fulgidus
Length = 527
Score = 77.8 bits (183), Expect = 2e-13
Identities = 33/74 (44%), Positives = 49/74 (66%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNID+++A ++G+ V+NAPG N +S E LML AR + A ++K G+W+R + G
Sbjct: 75 DNIDINAATQRGIVVVNAPGGNTISTAEHAIALMLAAARKIPQADRSVKEGKWERKKFMG 134
Query: 467 SELAGKTLAILGLG 508
EL GKT ++GLG
Sbjct: 135 IELRGKTAGVIGLG 148
Score = 47.6 bits (108), Expect = 3e-04
Identities = 20/58 (34%), Positives = 36/58 (62%)
Frame = +3
Query: 72 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 245
VL+ + + + + + G+ K +S+EEL+ E+P ++A+VVRS T+V EV+ A
Sbjct: 3 VLVAEPISEEAIDYMRKNGLEVEVKTGMSREELIREVPKYEAIVVRSQTKVDAEVIQA 60
Score = 38.3 bits (85), Expect = 0.18
Identities = 18/46 (39%), Positives = 27/46 (58%)
Frame = +1
Query: 508 RVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPSS 645
RVG EVA R A MN++ +DPFVS ++ Q ++ + + SS
Sbjct: 149 RVGFEVAKRCKALEMNVLAYDPFVSKERAEQIGVKLVDFDTLLASS 194
>UniRef50_Q8TYK0 Cluster: Predicted dehydrogenase related to
phosphoglycerate dehydrogenase; n=9; Archaea|Rep:
Predicted dehydrogenase related to phosphoglycerate
dehydrogenase - Methanopyrus kandleri
Length = 522
Score = 77.4 bits (182), Expect = 3e-13
Identities = 35/74 (47%), Positives = 52/74 (70%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNIDV +A ++G+ V+NAP ++++S E T L+L LAR + A +++ G WDR + G
Sbjct: 75 DNIDVKAATERGIIVVNAPESSSISVAEHTMGLILALARKIPQADRSVRRGEWDRKRFMG 134
Query: 467 SELAGKTLAILGLG 508
ELAGKTL ++GLG
Sbjct: 135 VELAGKTLGLIGLG 148
>UniRef50_O04130 Cluster: D-3-phosphoglycerate dehydrogenase,
chloroplast precursor; n=13; Magnoliophyta|Rep:
D-3-phosphoglycerate dehydrogenase, chloroplast
precursor - Arabidopsis thaliana (Mouse-ear cress)
Length = 624
Score = 77.4 bits (182), Expect = 3e-13
Identities = 43/138 (31%), Positives = 67/138 (48%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DN+D+ +A + G V+NAP AN ++A E L+ +AR+V A ++KAG+W+R+ Y G
Sbjct: 157 DNVDLQAATEHGCLVVNAPTANTVAAAEHGIALLASMARNVAQADASIKAGKWERSKYVG 216
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
L GKTLA++G G A + S+ A
Sbjct: 217 VSLVGKTLAVMGFGKVGTEVARRAKGLGMTVISHDPYAPADRARALGVDLVSFDQAISTA 276
Query: 647 DYITLHTPLIESTRNFIN 700
D+++LH PL +T+ N
Sbjct: 277 DFVSLHMPLTPATKKVFN 294
Score = 39.5 bits (88), Expect = 0.080
Identities = 24/67 (35%), Positives = 38/67 (56%)
Frame = +3
Query: 72 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 251
+L+ + +G LL +G + +S E+L ++ DAL+VRS T+VT+EV +A
Sbjct: 85 ILVTEKLGEAGVNLLREFGDVDCSY-DLSPEDLKKKVAESDALIVRSGTKVTREVFEA-A 142
Query: 252 K*RWSVV 272
K R VV
Sbjct: 143 KGRLKVV 149
>UniRef50_Q67TJ9 Cluster: Phosphoglycerate dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: Phosphoglycerate
dehydrogenase - Symbiobacterium thermophilum
Length = 540
Score = 77.0 bits (181), Expect = 4e-13
Identities = 38/75 (50%), Positives = 51/75 (68%), Gaps = 1/75 (1%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL-KAGRWDRALYT 463
DNIDV +A ++GV V+N PGAN S E L++ +AR++ A AL + GRWDR +
Sbjct: 73 DNIDVAAATERGVVVVNVPGANTYSTAEHAFGLLIAVARNIPQAHHALAREGRWDRMSFV 132
Query: 464 GSELAGKTLAILGLG 508
G+EL GKTL I+GLG
Sbjct: 133 GTELHGKTLGIIGLG 147
Score = 41.1 bits (92), Expect = 0.026
Identities = 19/35 (54%), Positives = 25/35 (71%)
Frame = +3
Query: 150 KISKEELLMEIPNHDALVVRSATQVTKEVLDAGVK 254
K++ EELL IP +DAL+ RS T+VT EVL G +
Sbjct: 27 KVTSEELLEIIPEYDALITRSETKVTAEVLARGTR 61
Score = 35.1 bits (77), Expect = 1.7
Identities = 13/24 (54%), Positives = 18/24 (75%)
Frame = +1
Query: 508 RVGREVATRMYAFGMNIIGFDPFV 579
R+G EVA R AFGM ++ +DP+V
Sbjct: 148 RIGSEVAVRARAFGMRVLAYDPYV 171
>UniRef50_P73821 Cluster: D-3-phosphoglycerate dehydrogenase; n=37;
Cyanobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Synechocystis sp. (strain PCC 6803)
Length = 554
Score = 77.0 bits (181), Expect = 4e-13
Identities = 44/142 (30%), Positives = 67/142 (47%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNIDV +A ++G+ V+N+P N ++A E +M+ LARH+ A+ ++K +W+R + G
Sbjct: 103 DNIDVPAATRQGIVVVNSPEGNTIAAAEHALAMMMALARHIPDANKSVKESKWERKQFIG 162
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
+E+ KTL ++GLG + A A
Sbjct: 163 TEVYKKTLGVVGLGKIGSHVAGVAKAMGMKLLAYDPFISQERADQIGCTLVDLDLLFSEA 222
Query: 647 DYITLHTPLIESTRNFINARCL 712
D+ITLH P T N INA L
Sbjct: 223 DFITLHIPKTPETANLINAETL 244
Score = 38.7 bits (86), Expect = 0.14
Identities = 18/59 (30%), Positives = 36/59 (61%)
Frame = +3
Query: 72 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 248
VL+ D + ++L K +S+ E++ +P +DA+++RSAT+VT++++ AG
Sbjct: 32 VLVSDSIDQVGIDILKQVA-QVDVKTGLSEAEIIDIVPEYDAIMLRSATKVTEKIIQAG 89
Score = 37.1 bits (82), Expect = 0.43
Identities = 14/40 (35%), Positives = 25/40 (62%)
Frame = +1
Query: 508 RVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELE 627
++G VA A GM ++ +DPF+S ++ Q CT ++L+
Sbjct: 177 KIGSHVAGVAKAMGMKLLAYDPFISQERADQIGCTLVDLD 216
>UniRef50_A7CYD6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Opitutaceae bacterium TAV2|Rep: D-3-phosphoglycerate
dehydrogenase - Opitutaceae bacterium TAV2
Length = 529
Score = 76.6 bits (180), Expect = 6e-13
Identities = 46/145 (31%), Positives = 73/145 (50%), Gaps = 3/145 (2%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DN+DV++A ++GV V+N P N ++ ELT T +L +R V A+ +++ G+WDR ++G
Sbjct: 76 DNVDVEAATERGVVVMNTPAGNTIATAELTFTHILCGSRPVSQAAASMREGKWDRKSFSG 135
Query: 467 SELAGKTLAILG---LGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFG 637
EL KTL ++G +GG AR + +A +
Sbjct: 136 VELFKKTLGVIGMGRIGGEVARRAVAFGMKVLAYDPYLAPSRAKAMQVEVA---TLDEIL 192
Query: 638 LLADYITLHTPLIESTRNFINARCL 712
ADYIT+H PL + T+ I+ L
Sbjct: 193 AQADYITVHMPLTDDTKYMIDEAAL 217
Score = 35.5 bits (78), Expect = 1.3
Identities = 14/42 (33%), Positives = 24/42 (57%)
Frame = +1
Query: 508 RVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDI 633
R+G EVA R AFGM ++ +DP+++ + L++I
Sbjct: 150 RIGGEVARRAVAFGMKVLAYDPYLAPSRAKAMQVEVATLDEI 191
>UniRef50_UPI0000E4762C Cluster: PREDICTED: similar to
D-3-phosphoglycerate dehydrogenase; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
D-3-phosphoglycerate dehydrogenase - Strongylocentrotus
purpuratus
Length = 493
Score = 76.2 bits (179), Expect = 8e-13
Identities = 49/140 (35%), Positives = 66/140 (47%), Gaps = 5/140 (3%)
Frame = +2
Query: 293 IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSE 472
IDV + G PG N LSA E TC ++ L+R + A LKAG+WDR + GSE
Sbjct: 46 IDVYDYLRMAWGSTYTPGGNTLSAAEHTCAMVCCLSRSLPQAHATLKAGKWDRKAFMGSE 105
Query: 473 LAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWS--WRTFGLL- 643
L GKTL I+GLG P+ A +++ W+T +
Sbjct: 106 LYGKTLGIVGLGRIGRE-----VAQRMQSFGMTTIGFDPIVPAEEAKQYNIEWQTLEQMW 160
Query: 644 --ADYITLHTPLIESTRNFI 697
DYIT+HTPLI T+ +
Sbjct: 161 PRCDYITVHTPLIPQTKGLL 180
Score = 55.2 bits (127), Expect = 2e-06
Identities = 23/44 (52%), Positives = 30/44 (68%)
Frame = +1
Query: 508 RVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWP 639
R+GREVA RM +FGM IGFDP V A++ Q++ LE +WP
Sbjct: 118 RIGREVAQRMQSFGMTTIGFDPIVPAEEAKQYNIEWQTLEQMWP 161
Score = 48.4 bits (110), Expect = 2e-04
Identities = 23/45 (51%), Positives = 27/45 (60%)
Frame = +3
Query: 51 MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIP 185
M +K VLI D V +CAE+L GI K+SKEELL EIP
Sbjct: 1 MAFSLKKVLISDSVSPRCAEILRENGIEVDNNTKLSKEELLAEIP 45
>UniRef50_A4YUP8 Cluster: Putative D-3-phosphoglycerate
dehydrogenase; n=1; Bradyrhizobium sp. ORS278|Rep:
Putative D-3-phosphoglycerate dehydrogenase -
Bradyrhizobium sp. (strain ORS278)
Length = 335
Score = 76.2 bits (179), Expect = 8e-13
Identities = 47/138 (34%), Positives = 67/138 (48%), Gaps = 1/138 (0%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNIDV++A ++G+ V A GAN+ S EL LM +AR + +K G WD+A G
Sbjct: 89 DNIDVEAADRRGIPVFVARGANSQSVAELAFALMFAVAREIPHLDARIKTGHWDKATTKG 148
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPR-WSWRTFGLL 643
++L G++L ++G G R +G A S A R S
Sbjct: 149 AQLLGRSLGVIGF-GEIGRILVGLVQPLHMEVRIFDPYMPADAEISGAERAGSLDEILTA 207
Query: 644 ADYITLHTPLIESTRNFI 697
+D I+LH PL+ TRN I
Sbjct: 208 SDVISLHCPLMPQTRNMI 225
>UniRef50_Q4L766 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Staphylococcus|Rep: D-3-phosphoglycerate dehydrogenase -
Staphylococcus haemolyticus (strain JCSC1435)
Length = 532
Score = 75.8 bits (178), Expect = 1e-12
Identities = 44/139 (31%), Positives = 65/139 (46%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNID+D+A +G+ VINAP N +SA E + ++L +AR++ A +LK W+R + G
Sbjct: 78 DNIDIDAATLQGILVINAPDGNTISATEHSVAMILAMARNIPQAHASLKNKEWNRKAFKG 137
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
EL KTL ++G G A + A
Sbjct: 138 VELYQKTLGVIGAGRIGIGVAQRLQSFGMKVLAYDPYLTEDKAQQLGVKLATIDEIARQA 197
Query: 647 DYITLHTPLIESTRNFINA 703
D++T+HTPL TR +NA
Sbjct: 198 DFVTVHTPLTPKTRGIVNA 216
Score = 35.5 bits (78), Expect = 1.3
Identities = 13/42 (30%), Positives = 26/42 (61%)
Frame = +1
Query: 508 RVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDI 633
R+G VA R+ +FGM ++ +DP+++ D+ Q +++I
Sbjct: 152 RIGIGVAQRLQSFGMKVLAYDPYLTEDKAQQLGVKLATIDEI 193
Score = 33.9 bits (74), Expect = 4.0
Identities = 18/59 (30%), Positives = 34/59 (57%), Gaps = 1/59 (1%)
Frame = +3
Query: 69 SVLIVDGVGAKCAE-LLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 242
++L+ D + + LLN K + ++ LL I +++ L+VRS TQVT++V++
Sbjct: 4 NILVSDPISTDGLQSLLNHSDFNVDIKTDLDEQSLLDIIGDYEGLIVRSQTQVTQQVIE 62
>UniRef50_UPI0000DC0E13 Cluster: 3-phosphoglycerate dehydrogenase;
n=4; Amniota|Rep: 3-phosphoglycerate dehydrogenase -
Rattus norvegicus
Length = 316
Score = 74.1 bits (174), Expect = 3e-12
Identities = 45/138 (32%), Positives = 66/138 (47%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DN+++++A K + V+N P +LSA ELTC +++ L R + P G+WD+ + G
Sbjct: 75 DNVNLEAAMTKSILVMNTPNGKSLSASELTCGMIVCLTRQIPP-------GKWDQEEFMG 127
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
+EL GKTL ILGLG A S + L
Sbjct: 128 TELNGKTLGILGLGRIGREVTTQMQAFRMKAVGFDPISSPEIAASFGVQQLLLEELWPLC 187
Query: 647 DYITLHTPLIESTRNFIN 700
D+IT+HTPL+ ST +N
Sbjct: 188 DFITVHTPLLLSTTGLLN 205
Score = 50.4 bits (115), Expect = 4e-05
Identities = 21/44 (47%), Positives = 29/44 (65%)
Frame = +1
Query: 508 RVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWP 639
R+GREV T+M AF M +GFDP S + A F ++ LE++WP
Sbjct: 142 RIGREVTTQMQAFRMKAVGFDPISSPEIAASFGVQQLLLEELWP 185
Score = 33.5 bits (73), Expect = 5.2
Identities = 20/60 (33%), Positives = 31/60 (51%)
Frame = +3
Query: 60 DIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 239
++ VLI D + C +LL G+ K +SKEEL++EI + + V + T E L
Sbjct: 5 NLHKVLISDILDPGCWKLLKDGGLQVVEKQNLSKEELIVEIQDCETTKVTADVTNTAEKL 64
>UniRef50_Q1NQ97 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=2;
Bacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - delta
proteobacterium MLMS-1
Length = 304
Score = 74.1 bits (174), Expect = 3e-12
Identities = 30/74 (40%), Positives = 50/74 (67%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DN+DV +A KKGV V+NAP NA +A E ++M+ L R++ A+ ++KAG+W++ + G
Sbjct: 75 DNVDVPAASKKGVVVMNAPDGNATTAAEHAVSMMMALTRNIPQATASMKAGKWEKKKFQG 134
Query: 467 SELAGKTLAILGLG 508
E+ K ++G+G
Sbjct: 135 HEVTAKVAGVVGIG 148
Score = 45.2 bits (102), Expect = 0.002
Identities = 22/58 (37%), Positives = 36/58 (62%)
Frame = +3
Query: 72 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 245
VLI D + +++ G+ + +S EEL+ IP +D LV+RSA++VT E+L+A
Sbjct: 3 VLISDNLAPVGEKIMRDAGLEVDVRTGLSPEELVKIIPAYDGLVIRSASKVTAEILEA 60
>UniRef50_Q8ZTC7 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Thermoproteaceae|Rep: D-3-phosphoglycerate dehydrogenase
- Pyrobaculum aerophilum
Length = 307
Score = 73.7 bits (173), Expect = 4e-12
Identities = 33/74 (44%), Positives = 48/74 (64%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DN+DV+ A KKG+ V++AP A + S ELT L+ +AR + + +KAG W + Y G
Sbjct: 75 DNVDVEYAVKKGIAVVSAPNAPSQSVAELTIGLLFSVARRIPLLNAKVKAGEWPKGKYIG 134
Query: 467 SELAGKTLAILGLG 508
E+AGKT+ I+G G
Sbjct: 135 IEIAGKTMGIVGFG 148
Score = 43.2 bits (97), Expect = 0.006
Identities = 22/60 (36%), Positives = 33/60 (55%)
Frame = +3
Query: 69 SVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 248
S LIVD V E L GI ISK++L+ I N++ L+ R ++ K+++DAG
Sbjct: 2 SALIVDKVDETLKERLERIGIKVDLAPGISKDDLIKIIKNYNILIFRGRLKIDKDIMDAG 61
>UniRef50_O67741 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Aquifex aeolicus|Rep: D-3-phosphoglycerate dehydrogenase
- Aquifex aeolicus
Length = 533
Score = 72.9 bits (171), Expect = 7e-12
Identities = 42/142 (29%), Positives = 68/142 (47%), Gaps = 2/142 (1%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DN+D++ A K+G+ V+N PGAN + A ELT ML + R+ A ++ +WDR + G
Sbjct: 77 DNVDIEEATKRGILVVNTPGANTIGATELTMMHMLTIMRNGHKAHESMLNYKWDRKKFMG 136
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLL- 643
EL G+ L I+GLG ++ + A + + +L
Sbjct: 137 EELYGRILGIIGLGNIGSQVAIRAKAFGMKVMAYDPYIPREKA-EKLGVKLVDNLHDMLR 195
Query: 644 -ADYITLHTPLIESTRNFINAR 706
D +T+H PL T+N I+ +
Sbjct: 196 EIDVLTIHAPLTHETKNMIDEK 217
Score = 39.1 bits (87), Expect = 0.11
Identities = 25/62 (40%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
Frame = +3
Query: 72 VLIVDGVGAKCAELLNAYG-IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 248
VLI D + + ELL + + IS EELL I + DA++ RS T VTKE+L+
Sbjct: 4 VLITDPIAPEGIELLQKDPEVEVYNEPDISYEELLEIIKDFDAIITRSRTPVTKELLERA 63
Query: 249 VK 254
K
Sbjct: 64 EK 65
>UniRef50_A4FIF2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
D-3-phosphoglycerate dehydrogenase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 316
Score = 72.9 bits (171), Expect = 7e-12
Identities = 36/74 (48%), Positives = 51/74 (68%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNID+D+A +G+ V+ APG+N+ + ELT LM+ AR + A TA+ AG W + LY G
Sbjct: 82 DNIDLDAARARGIPVVFAPGSNSRAVAELTFGLMIAAARRIAAAHTAVVAGDWPK-LY-G 139
Query: 467 SELAGKTLAILGLG 508
ELAG+TL ++G G
Sbjct: 140 PELAGRTLGVIGFG 153
Score = 32.7 bits (71), Expect = 9.2
Identities = 12/24 (50%), Positives = 18/24 (75%)
Frame = +1
Query: 508 RVGREVATRMYAFGMNIIGFDPFV 579
R+GR +A AFGM ++G+DPF+
Sbjct: 154 RIGRLLAGYAQAFGMTVVGYDPFL 177
>UniRef50_A7P9P5 Cluster: Chromosome chr3 scaffold_8, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr3 scaffold_8, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 653
Score = 72.9 bits (171), Expect = 7e-12
Identities = 42/138 (30%), Positives = 65/138 (47%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DN+D+ +A + G V+NAP AN ++A E L+ +AR+V A ++K+G+W R Y G
Sbjct: 186 DNVDLAAATEHGCLVVNAPTANTVAAAEHGIALLTAMARNVAQADASVKSGKWQRNKYVG 245
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
L GKTLA++G G + A + + A
Sbjct: 246 VSLVGKTLAVMGFGKVGSEVTRRAKGLGMHVIAHDPYAAADRARAIGVELVGFDEAISTA 305
Query: 647 DYITLHTPLIESTRNFIN 700
D+I+LH PL +T +N
Sbjct: 306 DFISLHMPLTPATSKMLN 323
Score = 37.9 bits (84), Expect = 0.24
Identities = 22/59 (37%), Positives = 35/59 (59%)
Frame = +3
Query: 69 SVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 245
+VL+ + +GA +LL + +S EEL +I DAL+VRS T+V++EV +A
Sbjct: 113 TVLVAEKLGAAGLDLLKDFANVDCAY-NLSPEELCTKISLCDALIVRSGTKVSREVFEA 170
>UniRef50_Q4WHR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Aspergillus fumigatus|Rep: D-3-phosphoglycerate
dehydrogenase - Aspergillus fumigatus (Sartorya
fumigata)
Length = 635
Score = 72.9 bits (171), Expect = 7e-12
Identities = 31/71 (43%), Positives = 51/71 (71%)
Frame = +2
Query: 296 DVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSEL 475
DV+ A K G+ V+N+P N +A E T L++ +AR++ A ++LK+G+W+R+ + G E+
Sbjct: 109 DVEEATKLGIVVVNSPSGNIGAAAEHTIALLMAMARNIPEACSSLKSGKWERSKFVGVEV 168
Query: 476 AGKTLAILGLG 508
GKTL+I+GLG
Sbjct: 169 KGKTLSIIGLG 179
Score = 34.3 bits (75), Expect = 3.0
Identities = 21/58 (36%), Positives = 32/58 (55%)
Frame = +3
Query: 72 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 245
VL+ + + LL A + + + +ELL IP ++ALVVRS T+VT +L A
Sbjct: 11 VLVPEKLSPDGLALLRA-SLEVDERRGLDADELLQIIPEYEALVVRSETKVTANLLRA 67
>UniRef50_A0V9Y4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Comamonadaceae|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Delftia acidovorans SPH-1
Length = 354
Score = 72.1 bits (169), Expect = 1e-11
Identities = 49/143 (34%), Positives = 67/143 (46%), Gaps = 5/143 (3%)
Frame = +2
Query: 290 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGS 469
NIDV +A ++G+ V PGANA S E+T LM AR + L+AGRW RA G
Sbjct: 107 NIDVAAASQRGIPVYVTPGANAQSVAEMTLGLMFAAARRIAWMDAELRAGRWSRA-QDGL 165
Query: 470 ELAGKTLAILGLGGSAAR-----WPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTF 634
EL+G+TL +LG G R LG A + + S
Sbjct: 166 ELSGRTLGLLGFGQVGQRVARVALALGMQVVAFDPAFDPACAPGPGAVAGVRMLGSVDEL 225
Query: 635 GLLADYITLHTPLIESTRNFINA 703
L+D ++LH PL TR+ ++A
Sbjct: 226 LPLSDVLSLHLPLNARTRHLLDA 248
>UniRef50_O33116 Cluster: D-3-phosphoglycerate dehydrogenase; n=28;
Actinomycetales|Rep: D-3-phosphoglycerate dehydrogenase
- Mycobacterium leprae
Length = 528
Score = 72.1 bits (169), Expect = 1e-11
Identities = 32/74 (43%), Positives = 50/74 (67%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DN+DVD+A +GV V+NAP +N SA E L+L +R + A +L+A W R+ ++G
Sbjct: 77 DNVDVDAATARGVLVVNAPTSNIHSAAEHALALLLAASRQIAEADASLRAHIWKRSSFSG 136
Query: 467 SELAGKTLAILGLG 508
+E+ GKT+ ++GLG
Sbjct: 137 TEIFGKTVGVVGLG 150
Score = 39.1 bits (87), Expect = 0.11
Identities = 16/42 (38%), Positives = 27/42 (64%)
Frame = +1
Query: 508 RVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDI 633
R+G+ VA R+ AFG ++I +DP+V+ + AQ M +D+
Sbjct: 151 RIGQLVAARIAAFGAHVIAYDPYVAPARAAQLGIELMSFDDL 192
Score = 33.1 bits (72), Expect = 6.9
Identities = 17/32 (53%), Positives = 21/32 (65%)
Frame = +3
Query: 159 KEELLMEIPNHDALVVRSATQVTKEVLDAGVK 254
+ +LL +P DAL+VRSAT V EVL A K
Sbjct: 34 RTKLLAAVPEADALLVRSATTVDAEVLAAAPK 65
>UniRef50_Q0EUV6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Thermoanaerobacter
ethanolicus|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Thermoanaerobacter
ethanolicus X514
Length = 320
Score = 71.7 bits (168), Expect = 2e-11
Identities = 35/74 (47%), Positives = 50/74 (67%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DN+D+++A KKG+ V N P AN S +L LMLVLAR+++ +K+G W R + G
Sbjct: 84 DNVDLNAAKKKGIVVTNTPNANNNSVADLVIGLMLVLARNLLAVDRIVKSGGWKRIM--G 141
Query: 467 SELAGKTLAILGLG 508
+E+ GKTL I+GLG
Sbjct: 142 TEIYGKTLGIIGLG 155
>UniRef50_A1RDF9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=1; Arthrobacter
aurescens TC1|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Arthrobacter aurescens
(strain TC1)
Length = 329
Score = 71.3 bits (167), Expect = 2e-11
Identities = 45/142 (31%), Positives = 67/142 (47%), Gaps = 2/142 (1%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW--DRALY 460
DN+D+ +A + V V + PG+N+ + E +L+L L R ++PA+ + AG W R
Sbjct: 74 DNVDIPAASEHSVWVTSTPGSNSNAVAEHVFSLLLSLTRRIIPAANRVLAGTWAEGRGDL 133
Query: 461 TGSELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGL 640
G EL+G+TL I+G G R A ++ A T
Sbjct: 134 VGFELSGRTLGIVGFGAIGKRVATIANGFGMRVLASDPIATAADAEAAGAVLVELDTLYD 193
Query: 641 LADYITLHTPLIESTRNFINAR 706
AD ITLH PL+ TR+ I+ R
Sbjct: 194 GADIITLHAPLLSGTRHMISPR 215
>UniRef50_A6PUG1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Victivallis vadensis
ATCC BAA-548|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Victivallis vadensis ATCC
BAA-548
Length = 524
Score = 70.9 bits (166), Expect = 3e-11
Identities = 30/74 (40%), Positives = 47/74 (63%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
+ ID+ A K + V+N PGAN+ + E +ML +RH++PA + + G W+++ + G
Sbjct: 75 NTIDIKYARKHDIDVMNTPGANSNAVAEEVVAMMLAASRHLIPADISTRKGDWEKSKFMG 134
Query: 467 SELAGKTLAILGLG 508
EL GKT+ ILGLG
Sbjct: 135 RELTGKTVGILGLG 148
>UniRef50_A0RW58 Cluster: Phosphoglycerate dehydrogenase; n=3;
Crenarchaeota|Rep: Phosphoglycerate dehydrogenase -
Cenarchaeum symbiosum
Length = 310
Score = 70.5 bits (165), Expect = 4e-11
Identities = 49/145 (33%), Positives = 68/145 (46%), Gaps = 3/145 (2%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNID+ +A GV VINA + EL +ML +AR + A ++ G+W + G
Sbjct: 79 DNIDLAAAESAGVRVINAVEGATTAVSELVLGMMLCMARQIPRADRGIRGGKWLKGELGG 138
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSI---APRWSWRTFG 637
+EL GK L I+GLG R LG A S + T
Sbjct: 139 TELKGKYLGIVGLGNIGRR--LGRLARGMNMNIIGHDVVPIDAEFSREVGLMKTDLNTLL 196
Query: 638 LLADYITLHTPLIESTRNFINARCL 712
+DY++LH PL++STR+ INA L
Sbjct: 197 GSSDYVSLHVPLLDSTRHMINAEKL 221
Score = 40.7 bits (91), Expect = 0.035
Identities = 19/58 (32%), Positives = 32/58 (55%)
Frame = +3
Query: 66 KSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 239
++VLI D +L G+ + K +I+ EEL E P + ++VRS T +T E++
Sbjct: 5 ETVLICDKADPVLGRILQQNGLRVSYKPEITPEELAAEAPGYSIIIVRSRTTITGEII 62
>UniRef50_Q7D366 Cluster: AGR_pAT_578p; n=2; Agrobacterium
tumefaciens str. C58|Rep: AGR_pAT_578p - Agrobacterium
tumefaciens (strain C58 / ATCC 33970)
Length = 317
Score = 70.1 bits (164), Expect = 5e-11
Identities = 34/79 (43%), Positives = 47/79 (59%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNID+D+A + G+ V NAPG NA + ELT L+L R + AL+ G WDR + G
Sbjct: 83 DNIDIDAAHRHGIAVTNAPGGNANAVAELTLGLILSAMRRIPYLHDALRGGAWDR--FVG 140
Query: 467 SELAGKTLAILGLGGSAAR 523
EL G+ + +LG G A +
Sbjct: 141 QELIGRRVGLLGFGNIARK 159
>UniRef50_A4MA79 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Petrotoga mobilis
SJ95|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Petrotoga mobilis SJ95
Length = 310
Score = 70.1 bits (164), Expect = 5e-11
Identities = 32/74 (43%), Positives = 46/74 (62%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNIDVD+A KG+ V+N PG N+LS EL ++L + RH+ + LK +W++ G
Sbjct: 76 DNIDVDTAKLKGITVLNTPGQNSLSVAELVIGMVLDIYRHITRGTIGLKNEQWEKKQLEG 135
Query: 467 SELAGKTLAILGLG 508
EL+ KT I+G G
Sbjct: 136 FELSQKTFGIIGFG 149
Score = 33.9 bits (74), Expect = 4.0
Identities = 16/34 (47%), Positives = 23/34 (67%)
Frame = +3
Query: 141 TKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 242
T + K+ L +I D L+VRSAT+VTKE+L+
Sbjct: 27 TSEHLEKDVLKDKIKEIDVLIVRSATKVTKEILE 60
>UniRef50_Q8R716 Cluster: Phosphoglycerate dehydrogenase and related
dehydrogenases; n=5; Clostridia|Rep: Phosphoglycerate
dehydrogenase and related dehydrogenases -
Thermoanaerobacter tengcongensis
Length = 533
Score = 69.7 bits (163), Expect = 7e-11
Identities = 34/74 (45%), Positives = 49/74 (66%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNIDV++A ++G+ V+N P N ++A ELT LML +AR++ A A G + R + G
Sbjct: 74 DNIDVEAATQRGILVVNTPAGNTIAAAELTIGLMLAIARNIPQAYHAALNGDFRRDRFKG 133
Query: 467 SELAGKTLAILGLG 508
EL GKT+ I+GLG
Sbjct: 134 VELNGKTVGIIGLG 147
Score = 44.0 bits (99), Expect = 0.004
Identities = 21/61 (34%), Positives = 37/61 (60%)
Frame = +3
Query: 72 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 251
+++ + + + L Y K IS+EELL I ++DA++VRSAT+V +E+++ G
Sbjct: 3 IIVTEKISENGIDYLKKYA-DVDVKTNISREELLEVIKDYDAIIVRSATKVDRELIEKGE 61
Query: 252 K 254
K
Sbjct: 62 K 62
Score = 32.7 bits (71), Expect = 9.2
Identities = 13/46 (28%), Positives = 28/46 (60%)
Frame = +1
Query: 508 RVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPSS 645
R+G VA+R+ AF M +I +DP++ ++ + ++ L+++ S
Sbjct: 148 RIGSLVASRLAAFNMRVIAYDPYMPDERFEKCGVKRVTLDELLEQS 193
>UniRef50_Q2LGV1 Cluster: Phosphoglycerate dehydrogenase; n=6;
Halobacteriaceae|Rep: Phosphoglycerate dehydrogenase -
Haloquadratum walsbyi
Length = 536
Score = 69.3 bits (162), Expect = 9e-11
Identities = 43/138 (31%), Positives = 62/138 (44%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNID+D+A + GV V NAP N +A E T + AR + A L+ G W ++ Y G
Sbjct: 79 DNIDIDAATEHGVIVANAPEGNVRAAAEHTVAMTFAGARSIPQAHARLRTGEWAKSEYLG 138
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
+E+ GKTL ++GLG A A + T A
Sbjct: 139 TEVNGKTLGVVGLGRVGQEVAKRLESLGMDLVAYDPYISEDRAERLGAELVEFDTCLERA 198
Query: 647 DYITLHTPLIESTRNFIN 700
+++T+HTPL T I+
Sbjct: 199 EFLTVHTPLTSETAGMIS 216
Score = 38.7 bits (86), Expect = 0.14
Identities = 14/40 (35%), Positives = 27/40 (67%)
Frame = +1
Query: 508 RVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELE 627
RVG+EVA R+ + GM+++ +DP++S D+ + +E +
Sbjct: 153 RVGQEVAKRLESLGMDLVAYDPYISEDRAERLGAELVEFD 192
Score = 36.7 bits (81), Expect = 0.56
Identities = 23/58 (39%), Positives = 30/58 (51%)
Frame = +3
Query: 72 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 245
VL+ D + E L A G + T I E LL I + +ALVVRS T V + V +A
Sbjct: 7 VLVTDPIDDAGLERLRAAGHSVETAYDIGDEALLNTITDVNALVVRSGTDVNEAVFEA 64
>UniRef50_Q8EMJ8 Cluster: Hypothetical conserved protein; n=1;
Oceanobacillus iheyensis|Rep: Hypothetical conserved
protein - Oceanobacillus iheyensis
Length = 319
Score = 68.9 bits (161), Expect = 1e-10
Identities = 44/140 (31%), Positives = 63/140 (45%), Gaps = 2/140 (1%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 463
DNIDV +A K G+ V N P AN + EL T ML RH++P A++AG +D R
Sbjct: 76 DNIDVKAATKYGIKVTNTPSANINAVAELVLTFMLASTRHLLPIDEAVRAGNFDIRNQLF 135
Query: 464 GSELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSS-IAPRWSWRTFGL 640
G EL GKT+ I+G G C + + S
Sbjct: 136 GYELNGKTVGIIGFGNIGRLIAEKCRLGLGMNIVVFDPYVTAESVEPYVELTESLEDLLR 195
Query: 641 LADYITLHTPLIESTRNFIN 700
++D +TLH P + +T + I+
Sbjct: 196 ISDVVTLHVPYVRATHHLIH 215
>UniRef50_Q18XF4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Desulfitobacterium
hafniense|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Desulfitobacterium
hafniense (strain DCB-2)
Length = 320
Score = 68.5 bits (160), Expect = 2e-10
Identities = 45/142 (31%), Positives = 63/142 (44%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
D+ID+ +A +G+ V NAPG NA S +L ML LAR +V A + G W + G
Sbjct: 84 DSIDLKAAAARGITVANAPGTNANSVADLAFGFMLSLARQIVSADKRTRDGFWGTVM--G 141
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
++ GKTL +LGLG + A
Sbjct: 142 KDVYGKTLGVLGLGQIGKGVIRRASGFDMNILGYDLVHHSQFEKEYRVRAATLEEIMSEA 201
Query: 647 DYITLHTPLIESTRNFINARCL 712
DYI++H PL+EST+N I+ L
Sbjct: 202 DYISVHLPLLESTKNIIDRSLL 223
>UniRef50_A6C2G1 Cluster: Phosphoglycerate dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: Phosphoglycerate
dehydrogenase - Planctomyces maris DSM 8797
Length = 316
Score = 68.5 bits (160), Expect = 2e-10
Identities = 33/74 (44%), Positives = 45/74 (60%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DN+D + A +KG+ V P AN+LS ELT LML L R + A G W+R +TG
Sbjct: 77 DNVDTEYAHEKGIVVCFTPDANSLSVAELTIGLMLALMRKIPEARQDTLTGGWNRLKFTG 136
Query: 467 SELAGKTLAILGLG 508
+EL GK+ ++GLG
Sbjct: 137 TELYGKSFGLIGLG 150
Score = 41.9 bits (94), Expect = 0.015
Identities = 21/48 (43%), Positives = 29/48 (60%), Gaps = 2/48 (4%)
Frame = +1
Query: 508 RVGREVATRMYAFGMNIIGFDPFVSAD--QCAQFHCTKMELEDIWPSS 645
R+G ATR AFGMNI+ DPF+ AD Q + + T + L+D+ S
Sbjct: 151 RIGSFTATRAKAFGMNILAADPFLKADAPQLKKLNATLLSLDDLLAES 198
>UniRef50_UPI00015BAF48 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Ignicoccus hospitalis
KIN4/I|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Ignicoccus hospitalis
KIN4/I
Length = 308
Score = 68.1 bits (159), Expect = 2e-10
Identities = 46/140 (32%), Positives = 67/140 (47%), Gaps = 2/140 (1%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNID+++A +KG+ V+NAP A + EL +M+VLAR + L G W++ + G
Sbjct: 77 DNIDLEAAKEKGIKVVNAPDALKNAVAELVIGMMVVLARRAHYSYRKLLEGEWEKVM--G 134
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLL- 643
ELAGKTL ++G G R + ++ LL
Sbjct: 135 FELAGKTLGVVGF-GRIGREVAKKAKALGMNVIAYDVVDLSETAKEMGVEFTQDLEELLR 193
Query: 644 -ADYITLHTPLIESTRNFIN 700
+D ++LH PL E TRN IN
Sbjct: 194 KSDVVSLHVPLTEQTRNMIN 213
>UniRef50_Q97N23 Cluster: D-3-phosphoglycerate dehydrogenase; n=10;
Clostridiaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Clostridium acetobutylicum
Length = 305
Score = 68.1 bits (159), Expect = 2e-10
Identities = 30/74 (40%), Positives = 46/74 (62%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNIDV A KG+ V N P A++ S EL M ++R + A+ ++ G+W++ YTG
Sbjct: 79 DNIDVTYARDKGLTVNNTPNASSASVAELAIGHMFAVSRFINTANVTMRQGKWEKKAYTG 138
Query: 467 SELAGKTLAILGLG 508
+E+ GKTL ++G G
Sbjct: 139 TEIFGKTLGLIGFG 152
Score = 42.7 bits (96), Expect = 0.009
Identities = 20/29 (68%), Positives = 25/29 (86%)
Frame = +3
Query: 159 KEELLMEIPNHDALVVRSATQVTKEVLDA 245
K+ELL++I D LVVRSAT+VTKEV+DA
Sbjct: 32 KDELLVKIKEFDVLVVRSATKVTKEVIDA 60
>UniRef50_A4ETV8 Cluster: Putative uncharacterized protein; n=6;
Alphaproteobacteria|Rep: Putative uncharacterized
protein - Roseobacter sp. SK209-2-6
Length = 166
Score = 67.3 bits (157), Expect = 3e-10
Identities = 39/83 (46%), Positives = 43/83 (51%)
Frame = -2
Query: 507 PRPRMARVLPASSLPVYRARSHLPAFSAVEAGTTWRARTNINVQVSSHALSALAPGALIT 328
P P RVL SS+P+ SHLPA+ EA WRA NI S + L G IT
Sbjct: 2 PAPMTPRVLLVSSVPMNLDFSHLPAWVEAEASGIWRATANIIAMACSAVVIILPNGVFIT 61
Query: 327 PTPFLPAESTSMLSTPAPARPTT 259
TP L A S SMLS P PAR T
Sbjct: 62 ITPRLEAASLSMLSVPMPARAMT 84
>UniRef50_Q6MN05 Cluster: Phosphoglycerate dehydrogenase; n=1;
Bdellovibrio bacteriovorus|Rep: Phosphoglycerate
dehydrogenase - Bdellovibrio bacteriovorus
Length = 328
Score = 66.1 bits (154), Expect = 8e-10
Identities = 43/138 (31%), Positives = 62/138 (44%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
D+ID+++ K GV V++ P AN SA +LT L+L ++ A +KAG W+R TG
Sbjct: 77 DHIDLEATQKWGVTVMHTPTANIESAAQLTWGLVLSCVNNIQAAHKMVKAGEWNRDQITG 136
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
ELAG+ I+GLG +R PR S+ A
Sbjct: 137 IELAGRNYGIVGLGRIGSRVAELAQAFGMNVVAYDPYQEDEVFERLHIPRLSYEEVLKTA 196
Query: 647 DYITLHTPLIESTRNFIN 700
D I+ H P T + +N
Sbjct: 197 DVISFHVPKTLETEHMLN 214
Score = 36.7 bits (81), Expect = 0.56
Identities = 13/42 (30%), Positives = 24/42 (57%)
Frame = +1
Query: 508 RVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDI 633
R+G VA AFGMN++ +DP+ + + H ++ E++
Sbjct: 151 RIGSRVAELAQAFGMNVVAYDPYQEDEVFERLHIPRLSYEEV 192
>UniRef50_A6ULR7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Sinorhizobium medicae
WSM419|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding - Sinorhizobium medicae WSM419
Length = 328
Score = 66.1 bits (154), Expect = 8e-10
Identities = 44/141 (31%), Positives = 66/141 (46%), Gaps = 2/141 (1%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
+N+D++SA ++GV V+ A GAN S EL L L +AR + +++A +W+R+ Y G
Sbjct: 79 NNVDIESATRRGVPVLIADGANGKSVAELAVGLALSVARKITTQDASIRARQWNRSAY-G 137
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLL- 643
+ AGKT I+ G R S+ W+ LL
Sbjct: 138 LQFAGKTAGIVAFGAIGRR---VAEILRAMDMRIIAFDPHARDRSTTGVDWTETLDELLQ 194
Query: 644 -ADYITLHTPLIESTRNFINA 703
+D ++LH PL TRN I A
Sbjct: 195 ESDLVSLHCPLTPETRNMITA 215
>UniRef50_A1IDH6 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Deltaproteobacteria|Rep: D-3-phosphoglycerate
dehydrogenase - Candidatus Desulfococcus oleovorans Hxd3
Length = 532
Score = 66.1 bits (154), Expect = 8e-10
Identities = 26/74 (35%), Positives = 46/74 (62%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DN+D+ +A K GV V+N P N ++ E T +M+ L R++ + +L++G+W++ G
Sbjct: 79 DNVDIPAATKHGVAVMNTPEGNVVTTAEHTIAMMMALTRNIPQGTLSLRSGQWEKKKLQG 138
Query: 467 SELAGKTLAILGLG 508
E+ KTL ++G G
Sbjct: 139 REVFNKTLGVIGFG 152
Score = 46.0 bits (104), Expect = 0.001
Identities = 25/60 (41%), Positives = 36/60 (60%), Gaps = 1/60 (1%)
Frame = +3
Query: 72 VLIVDGVGAK-CAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 248
VL+ D + A + L N G A K + EEL I +DAL++RSAT+VT ++L+AG
Sbjct: 5 VLVSDTIDASGVSRLENESGFAVDVKTGLPPEELKSIIGQYDALIIRSATKVTADILEAG 64
>UniRef50_Q3SK87 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=4; Proteobacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Thiobacillus
denitrificans (strain ATCC 25259)
Length = 391
Score = 65.7 bits (153), Expect = 1e-09
Identities = 51/156 (32%), Positives = 74/156 (47%), Gaps = 14/156 (8%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL-----------K 433
+NI V ++G+ V NAPGANA + EL ML+ AR++VPA + K
Sbjct: 64 NNIPVKKMSERGLPVFNAPGANANAVKELVIAGMLMGARNLVPALKFVESLDGTDEAMHK 123
Query: 434 AGRWDRALYTGSELAGKTLAILGLG--GS-AARWPLGCXXXXXXXXXXXXXXXXXXAPSS 604
A + + G EL G+TL ++GLG GS A + PS
Sbjct: 124 ATEAGKKQFAGMELPGRTLGVIGLGAIGSHIAEAAIRLGMNVVGYDPAITVDAAWRLPSQ 183
Query: 605 IAPRWSWRTFGLLADYITLHTPLIESTRNFINARCL 712
+ + AD++TLH PL+++TRN INA+ L
Sbjct: 184 VKRAENVDDVLRTADFVTLHVPLLDATRNLINAQRL 219
>UniRef50_A4FHH0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
D-3-phosphoglycerate dehydrogenase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 336
Score = 65.7 bits (153), Expect = 1e-09
Identities = 46/148 (31%), Positives = 68/148 (45%), Gaps = 6/148 (4%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
+ ID +SA ++GV V N PG NA++ EL LML L R V L+AGRWD+ Y+
Sbjct: 74 NTIDCESAAERGVHVCNVPGRNAIAVAELAFALMLALDRSVCDNVDDLRAGRWDKKRYSR 133
Query: 467 SE-LAGKTLAILGLG--GSA-ARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRW--SWR 628
+ + G+ + ++GLG G A A +I R+
Sbjct: 134 ARGIHGRRVGVVGLGQIGLAFAERAAAFGATVHAVAKPGRSPKTAERADAIGIRFVDDLT 193
Query: 629 TFGLLADYITLHTPLIESTRNFINARCL 712
T D ++LH P +TRN ++A L
Sbjct: 194 TLARTCDVLSLHVPATSATRNLVDADLL 221
>UniRef50_Q8XPB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Clostridium perfringens|Rep: D-3-phosphoglycerate
dehydrogenase - Clostridium perfringens
Length = 301
Score = 65.3 bits (152), Expect = 1e-09
Identities = 32/74 (43%), Positives = 44/74 (59%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNIDV A + G+ V N P A++ S E+ M LAR + ++ +KAG W + Y G
Sbjct: 78 DNIDVQYAEQNGIKVRNTPNASSSSVAEIILAHMFSLARFLNQSNITMKAGLWKKKDYVG 137
Query: 467 SELAGKTLAILGLG 508
EL GKTL I+G+G
Sbjct: 138 VELEGKTLGIIGMG 151
Score = 35.5 bits (78), Expect = 1.3
Identities = 19/61 (31%), Positives = 32/61 (52%)
Frame = +3
Query: 72 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 251
+L+ DG+ K L G T E+L +I D +V+RSAT++ +E++D +
Sbjct: 4 ILLNDGLDKKAISNLEFLGFDVDTN-HYDIEDLKEKIKKVDCIVIRSATKIRRELIDEAI 62
Query: 252 K 254
K
Sbjct: 63 K 63
>UniRef50_Q9RUU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Deinococci|Rep: D-3-phosphoglycerate dehydrogenase -
Deinococcus radiodurans
Length = 544
Score = 64.9 bits (151), Expect = 2e-09
Identities = 32/74 (43%), Positives = 47/74 (63%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNID++ A ++G+ V+NAP +N +SA EL ++ AR + + +AG WDR + G
Sbjct: 92 DNIDLEYASRRGLLVLNAPESNNVSAAELAVMHLMAAARGLTRSDRKTRAGEWDRK-FLG 150
Query: 467 SELAGKTLAILGLG 508
EL KTL I+GLG
Sbjct: 151 LELTDKTLGIVGLG 164
Score = 39.1 bits (87), Expect = 0.11
Identities = 17/44 (38%), Positives = 28/44 (63%)
Frame = +3
Query: 114 LNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 245
L+ G + + +EE L +P++DAL+ RS T+V +E+LDA
Sbjct: 33 LDHEGFQIDYQGNLEREETLRRLPDYDALITRSRTKVDRELLDA 76
>UniRef50_Q0FX01 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding subunit; n=3;
Rhodobacteraceae|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding subunit - Roseovarius sp.
HTCC2601
Length = 326
Score = 64.9 bits (151), Expect = 2e-09
Identities = 33/79 (41%), Positives = 46/79 (58%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNID+ + + G+ V N P ANA + EL LM +AR + ++ AG WDR + G
Sbjct: 84 DNIDIPACTEAGLPVCNTPAANADAVAELAVGLMFSMARWIPQGHASVTAGGWDRRI--G 141
Query: 467 SELAGKTLAILGLGGSAAR 523
++L GKTL I+GLG R
Sbjct: 142 TQLGGKTLGIVGLGNIGKR 160
>UniRef50_A7NGZ0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Roseiflexus castenholzii
DSM 13941|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding - Roseiflexus castenholzii DSM
13941
Length = 345
Score = 64.9 bits (151), Expect = 2e-09
Identities = 45/142 (31%), Positives = 63/142 (44%), Gaps = 2/142 (1%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNID+ +A ++G+ VIN P S E L+L LA+ VV A + W A G
Sbjct: 81 DNIDLAAATERGILVINTPDGPTESTAEHAVALVLALAKQVVAADHRFRTAGWSAARLRG 140
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLL- 643
E+ GKTL ++GLG R C A +++ LL
Sbjct: 141 VEVRGKTLGVVGLGRIGRRVAQICRQGLGMRVAAYDPLAPAEAFAALDVVHVETLDNLLP 200
Query: 644 -ADYITLHTPLIESTRNFINAR 706
++++TLH L STR I AR
Sbjct: 201 QSEFLTLHCALTPSTRGLIGAR 222
>UniRef50_A7HM61 Cluster: Glyoxylate reductase; n=1;
Fervidobacterium nodosum Rt17-B1|Rep: Glyoxylate
reductase - Fervidobacterium nodosum Rt17-B1
Length = 317
Score = 64.9 bits (151), Expect = 2e-09
Identities = 44/149 (29%), Positives = 76/149 (51%), Gaps = 11/149 (7%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRAL 457
+NID+++A ++G+ V N PG + ++ L+L +AR +V + ++ G+ W L
Sbjct: 77 NNIDIEAAKERGIYVTNTPGVLTEATADIAFALILAVARRIVESDKFVREGKFVGWKPKL 136
Query: 458 YTGSELAGKTLAILGLG--GSA-ARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWR 628
+ G +L GKTL ++G+G G A AR LG P I +++ +
Sbjct: 137 FLGYDLYGKTLGVIGMGRIGQAVARRALG-------FGMNIVYYNRNRLPEEIEKQYNAK 189
Query: 629 TFGL-----LADYITLHTPLIESTRNFIN 700
+ ++DYI+LHTPL + T + IN
Sbjct: 190 YVNIDELVEISDYISLHTPLTKETYHLIN 218
>UniRef50_A5URV2 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Roseiflexus sp.
RS-1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Roseiflexus sp. RS-1
Length = 323
Score = 64.9 bits (151), Expect = 2e-09
Identities = 45/142 (31%), Positives = 63/142 (44%), Gaps = 2/142 (1%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNID+ +A K+G+ VIN P S E L+L LA+ VV + L+ W A G
Sbjct: 80 DNIDIAAATKRGILVINTPDGPTESTAEHAVALLLALAKQVVASDRVLRTEGWRAARLRG 139
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLL- 643
E+ GKTL I+GLG R C +++ + LL
Sbjct: 140 IEVRGKTLGIVGLGRIGRRVAQICRQGLGMHVVAYDPPVPDETFATLDVARAATLDDLLP 199
Query: 644 -ADYITLHTPLIESTRNFINAR 706
A +++LH L TR+ I AR
Sbjct: 200 HAQFLSLHCALTPETRHLIGAR 221
>UniRef50_Q63VJ5 Cluster: D-3-phosphoglycerate dehydrogenase; n=8;
Burkholderiaceae|Rep: D-3-phosphoglycerate dehydrogenase
- Burkholderia pseudomallei (Pseudomonas pseudomallei)
Length = 424
Score = 64.5 bits (150), Expect = 2e-09
Identities = 44/140 (31%), Positives = 59/140 (42%)
Frame = +2
Query: 293 IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSE 472
+D+ +A G+ V NAP +N S EL ++L R V S AG W + E
Sbjct: 102 VDLPAAAHHGIPVFNAPFSNTRSVAELVIAEAILLLRRVPEKSVLAHAGEWAKGAGGSFE 161
Query: 473 LAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLADY 652
GKT+AI+G G A+ +G + S P S LAD
Sbjct: 162 ARGKTIAIVGYGNIGAQ--VGVLAEALGMRVVYYDVQAKLSLGSAQPARSLGEAIALADV 219
Query: 653 ITLHTPLIESTRNFINARCL 712
+TLH P ST N I+A L
Sbjct: 220 VTLHVPAHASTHNMIDASVL 239
>UniRef50_Q5WLJ2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Bacillus|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus clausii (strain KSM-K16)
Length = 316
Score = 64.5 bits (150), Expect = 2e-09
Identities = 42/140 (30%), Positives = 64/140 (45%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNIDVD+A K GV V N P AN + + +L+L LAR + + K G+W +L+ G
Sbjct: 79 DNIDVDAAKKHGVTVTNVPNANKHAVADFAFSLLLSLARQIPTGNEKTKKGKWP-SLF-G 136
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
+++ +TL I+GLG A + S +
Sbjct: 137 ADVYQQTLGIIGLGAIGKEVARRASGFSMTVLAYDPYIDRTYARKNGIEAVSLDALLQQS 196
Query: 647 DYITLHTPLIESTRNFINAR 706
D++T+H PL+ TR+ I R
Sbjct: 197 DFVTIHIPLLPETRHLIGER 216
>UniRef50_A0JVX0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Arthrobacter sp.
FB24|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Arthrobacter sp. (strain FB24)
Length = 319
Score = 64.1 bits (149), Expect = 3e-09
Identities = 43/131 (32%), Positives = 66/131 (50%), Gaps = 3/131 (2%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
D+IDV++A + G+ V+ APGAN+ ELT L+L +R + LK+G+W+R G
Sbjct: 95 DSIDVEAAERLGINVLTAPGANSQGVAELTIALILAGSRSIPWHDAQLKSGQWNRR--PG 152
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSW--RTFGL 640
+E++GK L ++G G R APS P +SW R L
Sbjct: 153 NEVSGKVLGLIGCGQIGRRVATMALGLGMKVIAFDEYPVTSFAPS---PDFSWAPRERVL 209
Query: 641 LADY-ITLHTP 670
+ + ++LHTP
Sbjct: 210 SSSHVVSLHTP 220
>UniRef50_Q0J5C2 Cluster: Os08g0447000 protein; n=11;
Viridiplantae|Rep: Os08g0447000 protein - Oryza sativa
subsp. japonica (Rice)
Length = 666
Score = 64.1 bits (149), Expect = 3e-09
Identities = 47/150 (31%), Positives = 66/150 (44%), Gaps = 12/150 (8%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA---------- 436
DN+D+ +A + G V+NAP AN ++A E L+ +AR+V A ALKA
Sbjct: 152 DNVDLQAATEAGCLVVNAPTANTVAAAEHGIALLASMARNVSQADAALKAVYSRTLTVFT 211
Query: 437 --GRWDRALYTGSELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIA 610
G+W R Y G L GKTLA++G G + A + A
Sbjct: 212 AQGKWQRTKYVGVSLVGKTLAVMGFGKVGSEVARRAKGLGMHVIAHDPYAPADRARAIGA 271
Query: 611 PRWSWRTFGLLADYITLHTPLIESTRNFIN 700
S+ AD+I+LH PL +T N
Sbjct: 272 ELVSFDEAIGRADFISLHMPLTPATSKVFN 301
Score = 39.9 bits (89), Expect = 0.060
Identities = 18/32 (56%), Positives = 25/32 (78%)
Frame = +3
Query: 153 ISKEELLMEIPNHDALVVRSATQVTKEVLDAG 248
+S ELL ++ DAL+VRS T+VT+EVL+AG
Sbjct: 106 MSPAELLAKVAQFDALIVRSGTKVTREVLEAG 137
>UniRef50_Q825H6 Cluster: Putative glycerate dehydrogenase; n=1;
Streptomyces avermitilis|Rep: Putative glycerate
dehydrogenase - Streptomyces avermitilis
Length = 325
Score = 63.7 bits (148), Expect = 4e-09
Identities = 49/145 (33%), Positives = 67/145 (46%), Gaps = 6/145 (4%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVIN--APGANALSACELTCTLMLVLARHVVPASTALKAGRW--DRA 454
D +D+D+A +G+ V N + GA + E T LML LA+ +VPA TAL W R
Sbjct: 82 DYVDLDAARARGLPVCNIGSSGAEQQNVAEQTFALMLALAKQLVPAHTALVDADWALPRL 141
Query: 455 LYTGSELAGKTLAILGLG--GSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWR 628
+ +EL+GKTL I+GLG G A A
Sbjct: 142 QRSITELSGKTLGIVGLGHIGEEVARRAVAFDMRIVYAGRERVGAEREARLGGARHVGLD 201
Query: 629 TFGLLADYITLHTPLIESTRNFINA 703
ADY+TLH PL E+TR+ ++A
Sbjct: 202 ELLRTADYVTLHAPLTEATRHLLDA 226
>UniRef50_A4WXD4 Cluster: Dimethylmenaquinone methyltransferase;
n=1; Rhodobacter sphaeroides ATCC 17025|Rep:
Dimethylmenaquinone methyltransferase - Rhodobacter
sphaeroides ATCC 17025
Length = 334
Score = 63.7 bits (148), Expect = 4e-09
Identities = 36/142 (25%), Positives = 60/142 (42%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNID+ +A +G+ V+ + G+N+ + E L L+L + + P + A+K G W + + G
Sbjct: 89 DNIDLAAAEARGIPVLRSMGSNSRAVAEHAIALALMLVKEIQPLNAAVKGGAWPKPTFIG 148
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
+ G L ++G GG A
Sbjct: 149 KDFQGAMLGLVGYGGIGRETARMAEALGMEVVVHDPYAPEAAEADGFAAAADLEAMLPAL 208
Query: 647 DYITLHTPLIESTRNFINARCL 712
D ++LH PL +TR+ I+AR L
Sbjct: 209 DILSLHCPLTSATRDLIDARRL 230
>UniRef50_A6PPS4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Victivallis vadensis
ATCC BAA-548|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Victivallis vadensis ATCC
BAA-548
Length = 316
Score = 63.3 bits (147), Expect = 6e-09
Identities = 42/141 (29%), Positives = 64/141 (45%), Gaps = 2/141 (1%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNI++ A +KG+ N PGA S E ++L+ AR + A+ + G W TG
Sbjct: 77 DNINLPRAAEKGIYCTNTPGALEQSVAECAIGMILLAARQFIAAADDCRNGLWQP--QTG 134
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRW--SWRTFGL 640
ELAGKTLA++G G +R + P A R+ +W
Sbjct: 135 CELAGKTLAVIGCGAIGSR--VAAIAKNGFGMSVTGVIRSAPRPDCPADRFVKNWSDAVA 192
Query: 641 LADYITLHTPLIESTRNFINA 703
AD+++LH P N+++A
Sbjct: 193 DADFVSLHIPGSPENLNYVSA 213
>UniRef50_A1HSQ7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Thermosinus
carboxydivorans Nor1|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Thermosinus
carboxydivorans Nor1
Length = 317
Score = 63.3 bits (147), Expect = 6e-09
Identities = 33/74 (44%), Positives = 43/74 (58%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
+ IDV +A G+ V PGAN +S EL LML +ARH+ ++ G W R TG
Sbjct: 82 NTIDVAAAAAYGIPVTITPGANNISVAELAIGLMLAVARHIPQMDGIVRRGGWSR--MTG 139
Query: 467 SELAGKTLAILGLG 508
SEL GK L I+G+G
Sbjct: 140 SELYGKVLGIIGMG 153
>UniRef50_A1AR04 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Pelobacter propionicus
DSM 2379|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Pelobacter propionicus
(strain DSM 2379)
Length = 357
Score = 63.3 bits (147), Expect = 6e-09
Identities = 37/145 (25%), Positives = 69/145 (47%), Gaps = 3/145 (2%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DN+DV+ A K+GV ++ P +A + E+ ML L+R ++ A +++ GRW++ ++G
Sbjct: 97 DNLDVEYARKRGVQLVRIPQPSARAVAEMAFAFMLALSRRLLEADRSMRNGRWEKHEFSG 156
Query: 467 SELAGKTLAILGLGGS---AARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFG 637
L KTL ++G+G + A+ + +
Sbjct: 157 YLLRDKTLGVVGIGNTGSCVAQMGVAWGMRVIGCVQHPSREREEGFCEKGIQMLEFDQVI 216
Query: 638 LLADYITLHTPLIESTRNFINARCL 712
ADY+++H PL ++TR ++A L
Sbjct: 217 ANADYLSIHVPLKDNTRRLLDADAL 241
>UniRef50_Q6W1I8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Rhizobium sp. NGR234|Rep: D-3-phosphoglycerate
dehydrogenase - Rhizobium sp. (strain NGR234)
Length = 327
Score = 62.9 bits (146), Expect = 7e-09
Identities = 47/143 (32%), Positives = 69/143 (48%), Gaps = 4/143 (2%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR-ALYT 463
D+ID D+A + GVG+ PG NA + + T ++L L R VV A+KAGRWDR T
Sbjct: 82 DSIDHDAAKEFGVGISVTPGMNAETVADQTLAMILGLMRRVVTQDQAVKAGRWDRVGEAT 141
Query: 464 GSELAGKTLAILG---LGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTF 634
+EL KT+ ++G +G + R LG S+ +
Sbjct: 142 PTELYRKTVGLIGAGIIGKAVIRRLLGFGVRVLYFDAMVEKVHGAERCGSLD-----QLL 196
Query: 635 GLLADYITLHTPLIESTRNFINA 703
G +D ++LH PL+ TR +NA
Sbjct: 197 G-SSDIVSLHAPLLADTRELMNA 218
>UniRef50_Q46VE6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=6;
Proteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Ralstonia
eutropha (strain JMP134) (Alcaligenes eutrophus)
Length = 312
Score = 62.5 bits (145), Expect = 1e-08
Identities = 46/144 (31%), Positives = 62/144 (43%), Gaps = 4/144 (2%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA-LYT 463
DNIDV + +G+ VI A GANA S E T +L R S + G+W RA L
Sbjct: 78 DNIDVAACRDRGIRVIPASGANARSVAEYVVTTAALLLRGAYLGSAEVAGGKWPRARLSE 137
Query: 464 GSELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLL 643
G E GKTL ++G G R P A T L
Sbjct: 138 GREALGKTLGLIGF-GDIGRQAAALAQAFGMRVVAHDPMLAPDDPVWSATGVVCMTLDAL 196
Query: 644 ---ADYITLHTPLIESTRNFINAR 706
+D ++LH PL+ +TR+ +NA+
Sbjct: 197 LAQSDAVSLHVPLVAATRHLMNAQ 220
>UniRef50_A6Q7Q2 Cluster: D-3-phosphoglycerate dehydrogenase; n=27;
Epsilonproteobacteria|Rep: D-3-phosphoglycerate
dehydrogenase - Sulfurovum sp. (strain NBC37-1)
Length = 529
Score = 62.5 bits (145), Expect = 1e-08
Identities = 45/141 (31%), Positives = 63/141 (44%), Gaps = 3/141 (2%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR-WDRALYT 463
DN+D+ + K+G+ V+N P AN ++A ELT ML R A LK R W R +
Sbjct: 80 DNVDIPGSSKQGIVVMNVPTANTIAAVELTLAHMLSCVRQFPYAHNNLKLDRVWRRQDWY 139
Query: 464 GSELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFG-- 637
G+EL K L I+G G +R +G + ++ + F
Sbjct: 140 GTELKDKKLGIIGFGNIGSR--VGKRAKAFEMDVLAYDPYIDPSKATDLDIGYTKNFEDI 197
Query: 638 LLADYITLHTPLIESTRNFIN 700
L D IT+HTP E T IN
Sbjct: 198 LACDIITIHTPKTEETIGMIN 218
>UniRef50_Q9WYG2 Cluster: Phosphoglycerate dehydrogenase, putative;
n=2; Thermotoga|Rep: Phosphoglycerate dehydrogenase,
putative - Thermotoga maritima
Length = 327
Score = 62.1 bits (144), Expect = 1e-08
Identities = 46/143 (32%), Positives = 66/143 (46%), Gaps = 3/143 (2%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL-KAGRWDRALYT 463
DNID+++A KKG+ V GAN+LS ELT + L+R +V A L RW+ +
Sbjct: 74 DNIDLEAATKKGIPVTITAGANSLSVAELTIAFIFALSRGLVWAHNKLFLERRWEGTV-- 131
Query: 464 GSELAGKTLAILGLG--GSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFG 637
G E++GKTL ++G G G C + P
Sbjct: 132 GQEVSGKTLGVVGFGSIGREVVKKAVCLGMNVLVYDPYVSKDSVRLLEA-TPVDDLEQLL 190
Query: 638 LLADYITLHTPLIESTRNFINAR 706
+D+++LH PL EST+N I R
Sbjct: 191 KESDFVSLHVPLNESTKNMIGER 213
Score = 35.9 bits (79), Expect = 0.98
Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 4/58 (6%)
Frame = +1
Query: 511 VGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKM-ELEDIWPSS---GLHHPAHSA 672
+GREV + GMN++ +DP+VS D T + +LE + S LH P + +
Sbjct: 148 IGREVVKKAVCLGMNVLVYDPYVSKDSVRLLEATPVDDLEQLLKESDFVSLHVPLNES 205
>UniRef50_O50096 Cluster: Putative uncharacterized protein PH1388;
n=1; Pyrococcus horikoshii|Rep: Putative uncharacterized
protein PH1388 - Pyrococcus horikoshii
Length = 119
Score = 62.1 bits (144), Expect = 1e-08
Identities = 41/93 (44%), Positives = 50/93 (53%), Gaps = 1/93 (1%)
Frame = -2
Query: 486 VLPASSLPVYRARSHLPAFSAVEAGTTWRARTNINVQVSSHALSALAPGALITPTPFLPA 307
VLP+SS+P+ +H P+ + A + A NIN SS L LA GAL T PF A
Sbjct: 5 VLPSSSIPIASFFAHTPSLIFLSAKAIFLATENINPTASSATLLELAAGALTTSIPFSLA 64
Query: 306 ESTSMLSTPAPARPTTFT-SRLRPTPLWSLELL 211
STSMLS P PA T + L T L +L LL
Sbjct: 65 ASTSMLSKPTPALAITLSFGALSITLLVTLGLL 97
>UniRef50_Q8FPW0 Cluster: Putative uncharacterized protein; n=1;
Corynebacterium efficiens|Rep: Putative uncharacterized
protein - Corynebacterium efficiens
Length = 161
Score = 61.7 bits (143), Expect = 2e-08
Identities = 42/110 (38%), Positives = 48/110 (43%)
Frame = -2
Query: 507 PRPRMARVLPASSLPVYRARSHLPAFSAVEAGTTWRARTNINVQVSSHALSALAPGALIT 328
P+P + VLP S P+ R H P+ A WRA S A L GAL T
Sbjct: 3 PKPTIPTVLPKISTPLKEERFHSPSRRVASAAGIWRAVDRSRETACSQAEWMLEVGALAT 62
Query: 327 PTPFLPAESTSMLSTPAPARPTTFTSRLRPTPLWSLELLNAQPERRGWVS 178
TP A S LS P PARPT F RL + S L A+ RR S
Sbjct: 63 MTPASVAAGMSTLSRPTPARPTIF--RLGAAAMTSASTLVAERTRRASAS 110
>UniRef50_A7CY19 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Opitutaceae bacterium
TAV2|Rep: D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Opitutaceae bacterium TAV2
Length = 318
Score = 61.7 bits (143), Expect = 2e-08
Identities = 43/143 (30%), Positives = 64/143 (44%), Gaps = 1/143 (0%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
D IDV A K + V+ PG N + E T L+L L ++++ + + ++G W R TG
Sbjct: 81 DKIDVAHATSKKIPVLFTPGVNHTTVAEHTFLLLLALEKNILFHTDSTRSGGWKRK--TG 138
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWR-TFGLL 643
EL KT+ I+GLG + A R + +
Sbjct: 139 HELLAKTIGIVGLGRIGKEVAIRARAFGMEVIAYDIYWDEAFAKQHNVKRVATKEEIFTS 198
Query: 644 ADYITLHTPLIESTRNFINARCL 712
ADYI+LHT L TR+ INA+ +
Sbjct: 199 ADYISLHTNLTPETRDMINAKTI 221
>UniRef50_UPI00015BD3AA Cluster: UPI00015BD3AA related cluster; n=1;
unknown|Rep: UPI00015BD3AA UniRef100 entry - unknown
Length = 332
Score = 61.3 bits (142), Expect = 2e-08
Identities = 43/138 (31%), Positives = 59/138 (42%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
D+IDV A KG+ V N P S E LML LAR + ++ G + + G
Sbjct: 77 DHIDVAYANSKGITVCNVPSYGEESVSEYAIMLMLALARKLRETIDNVEKGVYKTSNLRG 136
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
ELAGKTL ++G G AR L + I + ++
Sbjct: 137 IELAGKTLGVIGTGRIGARTALLARCFGMDVVCYDARQNQILIDAGI-KYLDFNELLSVS 195
Query: 647 DYITLHTPLIESTRNFIN 700
D+ITLH P + ST + IN
Sbjct: 196 DFITLHVPYLPSTHHLIN 213
>UniRef50_O86322 Cluster: POSSIBLE D-3-PHOSPHOGLYCERATE
DEHYDROGENASE SERA2; n=11; Mycobacterium|Rep: POSSIBLE
D-3-PHOSPHOGLYCERATE DEHYDROGENASE SERA2 - Mycobacterium
tuberculosis
Length = 326
Score = 61.3 bits (142), Expect = 2e-08
Identities = 32/89 (35%), Positives = 51/89 (57%), Gaps = 8/89 (8%)
Frame = +2
Query: 290 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR------ 451
N+D+ A G+ V++ P NA + E+T L+L +ARH++PA +++G R
Sbjct: 86 NVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAVARHLIPADADVRSGNIFRDGTIPY 145
Query: 452 ALYTGSELAGKTLAILGLG--GSAARWPL 532
+ G+E+AG T ++GLG G A RW L
Sbjct: 146 QRFRGAEIAGLTAGLVGLGAVGRAVRWRL 174
>UniRef50_A6UCB8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=2; Sinorhizobium|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Sinorhizobium medicae WSM419
Length = 310
Score = 61.3 bits (142), Expect = 2e-08
Identities = 32/80 (40%), Positives = 49/80 (61%), Gaps = 1/80 (1%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA-LKAGRWDRALYT 463
DN+ + ++G+G++ A GANA+ EL+ LML RH +PA TA ++AG W R+
Sbjct: 82 DNLPLPLLKERGIGILKAEGANAVGVAELSVGLMLAALRH-IPAETAGIRAGGWPRS--R 138
Query: 464 GSELAGKTLAILGLGGSAAR 523
G E+A +T+ I+G G R
Sbjct: 139 GREIAERTVGIIGCGAIGKR 158
>UniRef50_A6CKS4 Cluster: Putative uncharacterized protein; n=1;
Bacillus sp. SG-1|Rep: Putative uncharacterized protein
- Bacillus sp. SG-1
Length = 322
Score = 61.3 bits (142), Expect = 2e-08
Identities = 43/144 (29%), Positives = 65/144 (45%), Gaps = 2/144 (1%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 463
DNID+++A +G+ V NAP AN + E TL+L +R ++ +AL+ G ++ R
Sbjct: 76 DNIDLEAASDRGILVTNAPFANVNAVAEHVLTLILSGSRQLIQVDSALRNGDFEVRNRKF 135
Query: 464 GSELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSS-IAPRWSWRTFGL 640
G EL GKTL ++G G C SS + S
Sbjct: 136 GIELKGKTLGVVGFGNIGQLVAEKCHYGLGMDVLVYDPYVREENVSSYVQLNQSLSEVLA 195
Query: 641 LADYITLHTPLIESTRNFINARCL 712
+D +T+H P + ST + IN L
Sbjct: 196 SSDIVTIHVPYLPSTHHLINEEAL 219
>UniRef50_A1W9A3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Acidovorax sp.
JS42|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Acidovorax sp. (strain JS42)
Length = 339
Score = 61.3 bits (142), Expect = 2e-08
Identities = 42/143 (29%), Positives = 66/143 (46%), Gaps = 3/143 (2%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
D+ID+++ K+G+ V + P + S E L+L + RH+ A + G + TG
Sbjct: 83 DHIDLEACRKRGIAVCHVPDYGSASVAEHAFALLLGVTRHLTQAHERARQGSFAYRGLTG 142
Query: 467 SELAGKTLAILGL---GGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFG 637
EL G+TL I+GL G AR +G A S+ +W
Sbjct: 143 FELEGRTLGIVGLGRIGRHVARIAVGFGMDVLAYDPAFAASAARPAGVSLV---TWEQVL 199
Query: 638 LLADYITLHTPLIESTRNFINAR 706
+D ++LH P E+TR+ I+AR
Sbjct: 200 QGSDILSLHVPATEATRHLIDAR 222
>UniRef50_A0UAW1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=14; Burkholderiales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Burkholderia multivorans ATCC 17616
Length = 452
Score = 61.3 bits (142), Expect = 2e-08
Identities = 39/138 (28%), Positives = 60/138 (43%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
D ID D+A +G+ V A GANA + E L+L A+ V ++ G WD+A +
Sbjct: 220 DVIDQDAAAARGIAVRAAVGANAAAVAEHAWALILACAKSVPQLDMRMREGHWDKATHKS 279
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
EL G+TL ++GLG R + AP+ + T +
Sbjct: 280 VELDGRTLGLVGLGAIGRR--VAAIGVAFGMKVLAFDPFAKEAPAGVT-LVPLDTLYAES 336
Query: 647 DYITLHTPLIESTRNFIN 700
D +++H PL R +N
Sbjct: 337 DVVSMHCPLTADNRRMLN 354
>UniRef50_UPI000050F9E4 Cluster: COG0111: Phosphoglycerate
dehydrogenase and related dehydrogenases; n=1;
Brevibacterium linens BL2|Rep: COG0111: Phosphoglycerate
dehydrogenase and related dehydrogenases -
Brevibacterium linens BL2
Length = 314
Score = 60.9 bits (141), Expect = 3e-08
Identities = 30/76 (39%), Positives = 42/76 (55%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DN+D+D+A + G+ V N PG N + EL LML AR + + G W R G
Sbjct: 82 DNVDIDAAAELGIRVCNTPGVNHHAVAELALALMLACARRLNTVLAGVDDGGWPRE--AG 139
Query: 467 SELAGKTLAILGLGGS 514
+EL GK+L ++G G S
Sbjct: 140 TELRGKSLGVIGYGPS 155
>UniRef50_A0LN07 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Syntrophobacter
fumaroxidans MPOB|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 317
Score = 60.9 bits (141), Expect = 3e-08
Identities = 42/144 (29%), Positives = 66/144 (45%), Gaps = 2/144 (1%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 463
D ID+ A ++GV V+ P AN S E + ++LA+ + AL+ G W R
Sbjct: 78 DAIDLRCAKERGVKVVFTPTANTESVAEHFVGMAIMLAKMIRTGDIALRTGDWAARNRLI 137
Query: 464 GSELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSI-APRWSWRTFGL 640
G+EL GK L +LG G + C + A R S
Sbjct: 138 GTELHGKALGVLGFGRIGRQTARICRNGFAMNVIYYDVCDYPAVEKELQAKRVSGEEVFE 197
Query: 641 LADYITLHTPLIESTRNFINARCL 712
+D+I+++ PL+ STR+F+NA+ +
Sbjct: 198 QSDFISVNLPLLPSTRHFVNAKLI 221
>UniRef50_Q39LG4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=2; Burkholderia|Rep: D-isomer specific
2-hydroxyacid dehydrogenase - Burkholderia sp. (strain
383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
/ R18194))
Length = 312
Score = 60.1 bits (139), Expect = 5e-08
Identities = 26/74 (35%), Positives = 44/74 (59%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
+N+DV +A ++G+ V +APG NA + + ++L LAR P + A++AGRW +
Sbjct: 77 ENVDVAAAARRGIVVAHAPGTNASTVADHAIGMLLALARGYAPLTGAVRAGRWHASRAAR 136
Query: 467 SELAGKTLAILGLG 508
L G L ++G+G
Sbjct: 137 PTLTGAALGVIGMG 150
>UniRef50_A6G5P3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: D-3-phosphoglycerate
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 405
Score = 59.7 bits (138), Expect = 7e-08
Identities = 39/139 (28%), Positives = 59/139 (42%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
D ID++ A + GV V NAP +N S EL ++ L+R + S A GRW +
Sbjct: 77 DQIDLEVAAQSGVAVFNAPFSNTRSVAELVIAEIVCLSRQLFERSWAAHEGRWRKDAKGA 136
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
E+ GKTL I+G G ++ + +S + G +
Sbjct: 137 HEVRGKTLGIIGYGHIGSQLSVLAEAMGLRVRYHDIVNKLPLGNASASESLDALLAG--S 194
Query: 647 DYITLHTPLIESTRNFINA 703
D+++LH P TRN A
Sbjct: 195 DFVSLHVPNTPQTRNMFGA 213
>UniRef50_A4YFM2 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Metallosphaera sedula
DSM 5348|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Metallosphaera sedula DSM
5348
Length = 324
Score = 59.7 bits (138), Expect = 7e-08
Identities = 40/143 (27%), Positives = 61/143 (42%), Gaps = 3/143 (2%)
Frame = +2
Query: 293 IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL---YT 463
+D+ +A ++ + + PG N+++ ELT L + L R V+P + ++KAG+W
Sbjct: 85 VDLKAAKERDIIITYNPGGNSVAVAELTIMLAIALYRKVIPLALSVKAGKWSELKPKDTM 144
Query: 464 GSELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLL 643
G EL GK ILG G R S
Sbjct: 145 GHELEGKAWGILGFGNIGKRVAQLVTSLNCKVLGYDPYVSSEIMEKHGVKSLSLEELLSK 204
Query: 644 ADYITLHTPLIESTRNFINARCL 712
+D I++H PL ESTR+ IN+ L
Sbjct: 205 SDIISIHVPLTESTRHLINSERL 227
>UniRef50_Q3CIY1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=2;
Thermoanaerobacter ethanolicus|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Thermoanaerobacter ethanolicus ATCC 33223
Length = 319
Score = 59.3 bits (137), Expect = 9e-08
Identities = 44/144 (30%), Positives = 68/144 (47%), Gaps = 5/144 (3%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
D+IDV +A + G+ V NAPG N+ +L L+ +LAR + A+T K G+W + + G
Sbjct: 84 DSIDVKTANQLGIVVTNAPGTNSEEVADLAFGLLHMLARGLYQANTDTKNGKWIKPV--G 141
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGL-- 640
L+ KT+ I+G+G +G + +A + GL
Sbjct: 142 ISLSKKTIGIIGVG------TIGTAVAKRATGYDMNILGYDIKKNPLALGLGVKYVGLDE 195
Query: 641 ---LADYITLHTPLIESTRNFINA 703
AD+I+LH PL T N +NA
Sbjct: 196 LLSEADFISLHLPLTNDTLNILNA 219
>UniRef50_A7HEG1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=4; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase NAD-binding -
Anaeromyxobacter sp. Fw109-5
Length = 399
Score = 59.3 bits (137), Expect = 9e-08
Identities = 27/75 (36%), Positives = 47/75 (62%), Gaps = 1/75 (1%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
+ IDV +A ++GV V N PG N+++ EL L++ L R + L+AG+WD+ ++
Sbjct: 74 NTIDVAAASRRGVYVANCPGQNSIAVAELAIGLVVALDRRIPDNVALLRAGKWDKKTFSE 133
Query: 467 SE-LAGKTLAILGLG 508
++ L G+TL + G+G
Sbjct: 134 AQGLYGRTLGVAGVG 148
>UniRef50_A3PPC6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Rhodobacteraceae|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Rhodobacter sphaeroides (strain ATCC 17029
/ ATH 2.4.9)
Length = 331
Score = 59.3 bits (137), Expect = 9e-08
Identities = 47/142 (33%), Positives = 64/142 (45%), Gaps = 2/142 (1%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 463
D +D ++A +KGV V N PGANA S EL L L +AR + A AL+ G+ R
Sbjct: 74 DPVDKEAAARKGVVVANTPGANARSVAELAVGLALAVARRIPAADRALREGKTGFRESAR 133
Query: 464 GSELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGL- 640
SEL G+T ++G G S G R + GL
Sbjct: 134 FSELRGRTALVVGWGASGRE--TGRMLAQAFDMRLLVHSPRVPRIEG-GERVASLAEGLA 190
Query: 641 LADYITLHTPLIESTRNFINAR 706
AD ++LHTPL T + ++AR
Sbjct: 191 AADLVSLHTPLRPETHHMMDAR 212
>UniRef50_P13443 Cluster: Glycerate dehydrogenase; n=15;
Viridiplantae|Rep: Glycerate dehydrogenase - Cucumis
sativus (Cucumber)
Length = 382
Score = 59.3 bits (137), Expect = 9e-08
Identities = 33/82 (40%), Positives = 49/82 (59%), Gaps = 5/82 (6%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD---RAL 457
+N+DV++A K GV V N PG + EL +L L AR +V A ++AGR+D L
Sbjct: 98 NNVDVNAANKYGVAVGNTPGVLTETTAELAASLSLAAARRIVEADEFMRAGRYDGWLPNL 157
Query: 458 YTGSELAGKTLAILGLG--GSA 517
+ G+ L G+T+ ++G G GSA
Sbjct: 158 FVGNLLKGQTVGVIGAGRIGSA 179
>UniRef50_Q7X388 Cluster: Phosphoglycerate dehydrogenase; n=3;
Escherichia coli|Rep: Phosphoglycerate dehydrogenase -
Escherichia coli
Length = 306
Score = 58.8 bits (136), Expect = 1e-07
Identities = 45/138 (32%), Positives = 62/138 (44%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNIDVD A K + V A AN++S E+T +ML +R V + + G+ R + G
Sbjct: 82 DNIDVDYANSKDIVVHKALNANSISVAEMTILMMLSSSRKYVEIESQARNGKDIRLV--G 139
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
EL K L ++GLG PS I + S +
Sbjct: 140 YELYQKNLGLIGLGAIGQHVAHIAHSMGMTITAHDPHIDKSKVPSYIELK-SPDEIYQYS 198
Query: 647 DYITLHTPLIESTRNFIN 700
D I+LH PL++STRN IN
Sbjct: 199 DVISLHLPLLDSTRNIIN 216
>UniRef50_A7HBU0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=2; Anaeromyxobacter|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Anaeromyxobacter sp. Fw109-5
Length = 313
Score = 58.8 bits (136), Expect = 1e-07
Identities = 39/141 (27%), Positives = 64/141 (45%), Gaps = 3/141 (2%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW---DRAL 457
+++D+D+ ++GV V N PG + + L+L AR VV ++AG W D A
Sbjct: 78 NHLDLDACRRRGVLVTNTPGVVTDATADHAMALLLAAARRVVEGDRVVRAGGWTEVDPAW 137
Query: 458 YTGSELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFG 637
G+E+ GKT+ ++G G R A + A R
Sbjct: 138 MLGTEVTGKTVGVVGFG----RIGQAFARRARGFDTRVLYTSPRDAGVAWAERVGLERLL 193
Query: 638 LLADYITLHTPLIESTRNFIN 700
AD+++LH PL+ +TRN ++
Sbjct: 194 AEADFVSLHVPLVPATRNLLS 214
>UniRef50_Q97ZK1 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Sulfolobaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Sulfolobus solfataricus
Length = 326
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/74 (40%), Positives = 44/74 (59%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNID + A K+ + ++ APGA+ SA ELT L++ AR + + K G + + G
Sbjct: 92 DNIDTEEASKRNIKIVYAPGASTDSAAELTIGLLIAAARKLYDSMNMAKGGIFKK--IEG 149
Query: 467 SELAGKTLAILGLG 508
ELAGKT+ I+G G
Sbjct: 150 IELAGKTIGIVGFG 163
Score = 43.6 bits (98), Expect = 0.005
Identities = 26/65 (40%), Positives = 36/65 (55%)
Frame = +3
Query: 57 VDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEV 236
+D K VLI D V L G+ K +I++EELL I + L+VRS T+V KE+
Sbjct: 16 LDFK-VLITDPVDQYMIRTLQNNGLIVDYKPEITREELLKIIDQYQVLIVRSRTKVDKEI 74
Query: 237 LDAGV 251
+ GV
Sbjct: 75 IRYGV 79
>UniRef50_O28495 Cluster: 2-hydroxyacid dehydrogenase, putative;
n=4; Archaea|Rep: 2-hydroxyacid dehydrogenase, putative
- Archaeoglobus fulgidus
Length = 323
Score = 58.8 bits (136), Expect = 1e-07
Identities = 45/146 (30%), Positives = 62/146 (42%), Gaps = 6/146 (4%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR---AL 457
+NIDV++A K + V N G NALS E T L L R ++ A ++ +GRW++ A
Sbjct: 82 NNIDVEAAKKLSITVANVGGVNALSVAEHTVMFALALLRRLIYAHNSVLSGRWEQDEMAN 141
Query: 458 YTGSELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFG 637
EL GKT I+G+G + +R F
Sbjct: 142 LGVYELHGKTWGIIGMGAQGREVTKRLQGWGVKIIYHDVRRAEDIEEYGV----EFRDFD 197
Query: 638 LL---ADYITLHTPLIESTRNFINAR 706
L AD ++LH PL E TR I R
Sbjct: 198 ALLREADIVSLHVPLTEETRGMIGER 223
>UniRef50_A6DQ00 Cluster: SerA; n=1; Lentisphaera araneosa
HTCC2155|Rep: SerA - Lentisphaera araneosa HTCC2155
Length = 522
Score = 58.4 bits (135), Expect = 2e-07
Identities = 38/142 (26%), Positives = 56/142 (39%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
+ ID+ A K + V+N PGAN+ + E +M+ AR + + +AG W +A G
Sbjct: 76 NTIDIQYARSKDITVMNTPGANSNAVAEEAVGMMISCARFFIEGDRSTRAGEWKKAQLQG 135
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
EL GKT+ I G G A S +
Sbjct: 136 FELTGKTVGIAGFGNIGQLLAKRLSGFEVDILVYDPFVSEDKLAEFGAKNVSLEELFAGS 195
Query: 647 DYITLHTPLIESTRNFINARCL 712
D+I+LH P + T N I+ L
Sbjct: 196 DFISLHMPATKETANVISTDLL 217
Score = 41.5 bits (93), Expect = 0.020
Identities = 20/54 (37%), Positives = 34/54 (62%), Gaps = 3/54 (5%)
Frame = +1
Query: 511 VGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPSS---GLHHPA 663
+G+ +A R+ F ++I+ +DPFVS D+ A+F + LE+++ S LH PA
Sbjct: 151 IGQLLAKRLSGFEVDILVYDPFVSEDKLAEFGAKNVSLEELFAGSDFISLHMPA 204
>UniRef50_Q7WM64 Cluster: Putative dehydrogenase; n=2;
Bordetella|Rep: Putative dehydrogenase - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 330
Score = 58.0 bits (134), Expect = 2e-07
Identities = 28/73 (38%), Positives = 42/73 (57%), Gaps = 1/73 (1%)
Frame = +2
Query: 293 IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG-S 469
ID+ +A + G+ V+N PGANA S EL + + L + VP A++ G W+ G
Sbjct: 81 IDLAAAERLGIPVVNTPGANARSVAELALAMAMALLKRTVPLDQAVRQGNWNIRYEAGLR 140
Query: 470 ELAGKTLAILGLG 508
EL+G +L I+G G
Sbjct: 141 ELSGMSLGIVGFG 153
>UniRef50_Q1K3M3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Desulfuromonas acetoxidans DSM 684|Rep:
D-3-phosphoglycerate dehydrogenase - Desulfuromonas
acetoxidans DSM 684
Length = 528
Score = 58.0 bits (134), Expect = 2e-07
Identities = 38/140 (27%), Positives = 62/140 (44%), Gaps = 1/140 (0%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
+NI +D+A KG+ V N P + + E +M+ LAR + A ++ G+W + G
Sbjct: 76 ENIAMDAANIKGIVVTNTPLGSTTTIAEHAIAMMMSLARLIPQAHESMSQGKWQSTEFLG 135
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSI-APRWSWRTFGLL 643
S++ KTL ++G GG R + + + A + S
Sbjct: 136 SDINDKTLGVIG-GGKIGRRVIEYARGLHMHVNLYDPYLSEEVITRLGASKVSLEDLLST 194
Query: 644 ADYITLHTPLIESTRNFINA 703
AD+I+LH PL T +NA
Sbjct: 195 ADFISLHLPLTLETEQILNA 214
Score = 35.5 bits (78), Expect = 1.3
Identities = 22/59 (37%), Positives = 34/59 (57%), Gaps = 1/59 (1%)
Frame = +3
Query: 72 VLIVDGVGAKCAELLN-AYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 245
VLI D + +L + A GI + I+ + LL I N+DAL+VR T V++E++ A
Sbjct: 3 VLISDNFSSAGLKLFDEAEGITADYQPGITHDNLLKIINNYDALIVRGGTTVSEELIFA 61
>UniRef50_Q0K073 Cluster: D-3-Phosphoglycerate dehydrogenase; n=2;
Burkholderiales|Rep: D-3-Phosphoglycerate dehydrogenase
- Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428
/ Stanier 337)(Cupriavidus necator (strain ATCC 17699 /
H16 / DSM 428 / Stanier337))
Length = 360
Score = 58.0 bits (134), Expect = 2e-07
Identities = 30/80 (37%), Positives = 46/80 (57%), Gaps = 1/80 (1%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 463
D ID+D+ + GV V+N G NA S E+T LML + R + + +L+A + R
Sbjct: 96 DTIDIDACTEAGVAVLNQAGGNADSVAEMTLGLMLAVLRRIAESDRSLRAHNCESREDLM 155
Query: 464 GSELAGKTLAILGLGGSAAR 523
G EL G+TL ++G+G + R
Sbjct: 156 GHELRGRTLGLVGVGHAGRR 175
>UniRef50_Q03WU1 Cluster: Lactate dehydrogenase related
dehydrogenase; n=1; Leuconostoc mesenteroides subsp.
mesenteroides ATCC 8293|Rep: Lactate dehydrogenase
related dehydrogenase - Leuconostoc mesenteroides subsp.
mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 312
Score = 58.0 bits (134), Expect = 2e-07
Identities = 32/76 (42%), Positives = 45/76 (59%), Gaps = 2/76 (2%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR--WDRALY 460
DNI V+SA K GV V N PGANA++ EL TL+L + R V A+ +++ G A
Sbjct: 77 DNIPVESATKHGVWVTNTPGANAIAVAELAVTLILTVLRKVNQATNSVQKGEALTYPASL 136
Query: 461 TGSELAGKTLAILGLG 508
G L+GK + ++G G
Sbjct: 137 MGHNLSGKIIGLIGYG 152
>UniRef50_Q5KN70 Cluster: D-3-phosphoglycerate dehydrogenase 2,
putative; n=2; Filobasidiella neoformans|Rep:
D-3-phosphoglycerate dehydrogenase 2, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 508
Score = 58.0 bits (134), Expect = 2e-07
Identities = 24/74 (32%), Positives = 46/74 (62%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
+ +D++ A K+G+ V N+P +N+ S EL + ++ L+R ++ + ++AG W++
Sbjct: 174 NQVDLEHAAKRGIAVFNSPFSNSRSVAELVISEIIALSRQIIDRTHEMRAGIWNKLSKNC 233
Query: 467 SELAGKTLAILGLG 508
E+ GKTL I+G G
Sbjct: 234 WEIRGKTLGIVGYG 247
Score = 41.9 bits (94), Expect = 0.015
Identities = 20/60 (33%), Positives = 40/60 (66%), Gaps = 2/60 (3%)
Frame = +3
Query: 72 VLIVDGVGAKCAELLNAYG--IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 245
+L+++ + A+ L + G + TKA ++EEL+ ++PN+ A+ +RS T++T +V+DA
Sbjct: 101 ILLLENINLDAADYLKSQGYEVDHVTKA-YTEEELIAKLPNYHAIGIRSKTKITAKVIDA 159
>UniRef50_Q81T55 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=41; cellular
organisms|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Bacillus anthracis
Length = 323
Score = 56.8 bits (131), Expect = 5e-07
Identities = 29/77 (37%), Positives = 40/77 (51%), Gaps = 3/77 (3%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA---GRWDRAL 457
DNID AG+KG+ V N P + + ELT L+L AR + T + W
Sbjct: 77 DNIDYTYAGEKGIAVTNTPKVSTEATAELTFALLLAAARRIPEGDTLCRTTGFNGWAPLF 136
Query: 458 YTGSELAGKTLAILGLG 508
+ G E+ GKT+ I+GLG
Sbjct: 137 FLGREVHGKTIGIIGLG 153
Score = 32.7 bits (71), Expect = 9.2
Identities = 19/47 (40%), Positives = 29/47 (61%), Gaps = 1/47 (2%)
Frame = +3
Query: 108 ELLNAYGIATTTKAK-ISKEELLMEIPNHDALVVRSATQVTKEVLDA 245
ELL + + K + IS +EL + + DAL+ +T+VTKEV+DA
Sbjct: 16 ELLKDHDVEMYDKEELISLDELTERVKDKDALLSLLSTKVTKEVIDA 62
>UniRef50_Q3KBX8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Pseudomonas|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Pseudomonas fluorescens (strain PfO-1)
Length = 324
Score = 56.4 bits (130), Expect = 7e-07
Identities = 31/76 (40%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW--DRALY 460
DN+D +A + GV V N PGAN S E L+L ++R V A+ + W DR
Sbjct: 74 DNVDYKAAAELGVWVTNTPGANRRSVVEHVFALLLGISRKVQLATDQTRNNIWAQDRLSL 133
Query: 461 TGSELAGKTLAILGLG 508
TG EL G+TL ++G G
Sbjct: 134 TGIELEGRTLGLIGFG 149
>UniRef50_Q8CPW2 Cluster: Glycerate dehydrogenase; n=4;
Staphylococcus|Rep: Glycerate dehydrogenase -
Staphylococcus epidermidis (strain ATCC 12228)
Length = 323
Score = 56.0 bits (129), Expect = 9e-07
Identities = 29/77 (37%), Positives = 44/77 (57%), Gaps = 3/77 (3%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR---AL 457
DNID+ A K GV V N P + EL TLML +AR ++ A++ ++ G+W L
Sbjct: 79 DNIDISLAKKHGVVVTNTPHVLTETTAELGFTLMLTVARRIIEATSYIQEGKWKSWGPYL 138
Query: 458 YTGSELAGKTLAILGLG 508
+G ++ G T+ I G+G
Sbjct: 139 LSGKDVYGATVGIFGMG 155
>UniRef50_A0Z6W9 Cluster: Spermidine/putrescine ABC transporter
ATP-binding subunit; n=4; Bacteria|Rep:
Spermidine/putrescine ABC transporter ATP-binding
subunit - marine gamma proteobacterium HTCC2080
Length = 395
Score = 56.0 bits (129), Expect = 9e-07
Identities = 47/158 (29%), Positives = 71/158 (44%), Gaps = 16/158 (10%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHV---VPASTALKAGRWDRAL 457
+NI + + G+ V N PGANA + EL +L+ +R + + +L ++A+
Sbjct: 62 NNIPLSHCTELGIPVFNTPGANANAVKELVAAGLLLASRDILGGIDFVNSLSEDLDEQAM 121
Query: 458 ----------YTGSELAGKTLAILGLG--GS-AARWPLGCXXXXXXXXXXXXXXXXXXAP 598
+ G+EL GKTL +LGLG GS A+ L P
Sbjct: 122 GPLLEAEKKRFAGAELKGKTLGVLGLGAIGSLVAQLGLELGMDVVGFDPAISIEAAWQLP 181
Query: 599 SSIAPRWSWRTFGLLADYITLHTPLIESTRNFINARCL 712
SS+ + + ADYI++H P IEST + IN L
Sbjct: 182 SSVKRMENMQALFSRADYISIHVPAIESTHHLINQETL 219
>UniRef50_Q8EP33 Cluster: Glycerate dehydrogenase; n=2;
Bacillaceae|Rep: Glycerate dehydrogenase -
Oceanobacillus iheyensis
Length = 314
Score = 55.6 bits (128), Expect = 1e-06
Identities = 30/74 (40%), Positives = 41/74 (55%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNID A +KG+ V N PG NA + +L LML AR++ + L+ G W+ L G
Sbjct: 81 DNIDFKYAREKGIPVTNTPGQNADAVADLAIGLMLATARNIPAKNEELRNGNWE--LSMG 138
Query: 467 SELAGKTLAILGLG 508
E+ K L I+G G
Sbjct: 139 IEIFQKKLGIIGFG 152
>UniRef50_Q0ETU3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Thermoanaerobacter
ethanolicus X514|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Thermoanaerobacter
ethanolicus X514
Length = 324
Score = 55.6 bits (128), Expect = 1e-06
Identities = 29/75 (38%), Positives = 44/75 (58%), Gaps = 1/75 (1%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 463
DNIDV++A +KG+ V N P N LS E T ++L L++ + A+++G W R
Sbjct: 75 DNIDVNAATEKGILVCNLPAVNNLSVAEHTIAMILNLSKQLSLMDKAVRSGNWGARNSNI 134
Query: 464 GSELAGKTLAILGLG 508
E+ GK L I+G+G
Sbjct: 135 SVEIEGKVLGIVGMG 149
>UniRef50_A5V6T9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Sphingomonas wittichii
RW1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Sphingomonas wittichii RW1
Length = 317
Score = 55.6 bits (128), Expect = 1e-06
Identities = 40/141 (28%), Positives = 60/141 (42%), Gaps = 3/141 (2%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD---RAL 457
D+ID+D+ +G+ + N PG + + + L+L R + A+ L+ GRW +
Sbjct: 80 DHIDLDAVRARGLPMFNTPGILSNAVADQAMLLLLAATRRMAEATALLREGRWTDLWSSH 139
Query: 458 YTGSELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFG 637
G ELAG+TL I GLG R A ++ A + F
Sbjct: 140 ILGVELAGRTLGIYGLGDIGRRVARRATAFGMRLVYHNRRRAVDEAGATFAA--TAEEFL 197
Query: 638 LLADYITLHTPLIESTRNFIN 700
AD + L P TRNF+N
Sbjct: 198 ASADILLLAAPSTGETRNFLN 218
>UniRef50_A7P8C8 Cluster: Chromosome chr3 scaffold_8, whole genome
shotgun sequence; n=3; core eudicotyledons|Rep:
Chromosome chr3 scaffold_8, whole genome shotgun
sequence - Vitis vinifera (Grape)
Length = 418
Score = 55.6 bits (128), Expect = 1e-06
Identities = 31/82 (37%), Positives = 48/82 (58%), Gaps = 5/82 (6%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD---RAL 457
+N+DV++A K GV V N PG + EL +L + AR +V A ++AG +D L
Sbjct: 98 NNVDVNAANKYGVAVGNTPGVLTETTAELAASLSMAAARRIVEADEFMRAGLYDGWLPHL 157
Query: 458 YTGSELAGKTLAILGLG--GSA 517
+ G+ L G+T+ ++G G GSA
Sbjct: 158 FVGNLLRGQTVGVIGAGRIGSA 179
>UniRef50_O58320 Cluster: Glyoxylate reductase; n=16; cellular
organisms|Rep: Glyoxylate reductase - Pyrococcus
horikoshii
Length = 334
Score = 55.6 bits (128), Expect = 1e-06
Identities = 28/81 (34%), Positives = 44/81 (54%), Gaps = 7/81 (8%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR----- 451
DNID++ A K+G+ V N P + +L L+L ARHVV +++G W +
Sbjct: 79 DNIDIEEATKRGIYVTNTPDVLTDATADLAFALLLATARHVVKGDRFVRSGEWKKRGVAW 138
Query: 452 --ALYTGSELAGKTLAILGLG 508
+ G ++ GKT+ I+GLG
Sbjct: 139 HPKWFLGYDVYGKTIGIIGLG 159
>UniRef50_Q7UQC8 Cluster: Probable 2-hydroxyacid dehydrogenase; n=1;
Pirellula sp.|Rep: Probable 2-hydroxyacid dehydrogenase
- Rhodopirellula baltica
Length = 406
Score = 55.2 bits (127), Expect = 2e-06
Identities = 38/143 (26%), Positives = 62/143 (43%), Gaps = 4/143 (2%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRAL 457
+NIDVD+A +GV V N P + +L +L+ +RHV+PA ++ G W+
Sbjct: 165 NNIDVDAAKTRGVVVGNTPDVLTDATADLAVSLLFAASRHVLPAGNQVREGEWKTWEPTG 224
Query: 458 YTGSELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSI-APRWSWRTF 634
+ G E + KTL I+G+G + R T
Sbjct: 225 WLGVEPSDKTLGIVGMGRIGKATAKRLVGGWGMNLLYTSRSDQGDVEKELGGRRVELDTL 284
Query: 635 GLLADYITLHTPLIESTRNFINA 703
+D++++H L + TRN I+A
Sbjct: 285 LAESDFVSVHVALTDETRNLIDA 307
>UniRef50_Q21A61 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Rhodopseudomonas
palustris BisB18|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Rhodopseudomonas palustris
(strain BisB18)
Length = 321
Score = 55.2 bits (127), Expect = 2e-06
Identities = 29/74 (39%), Positives = 42/74 (56%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
++ID+ +A GV V+ A GANA S E LML L + V ++ G WD+ Y G
Sbjct: 81 NDIDLAAAKALGVPVLAAVGANAHSVAEHAFMLMLALIKDVRNQDAYVRGGGWDKKGYRG 140
Query: 467 SELAGKTLAILGLG 508
EL G+ L ++G+G
Sbjct: 141 RELRGRVLGLVGIG 154
>UniRef50_A3UGW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Oceanicaulis alexandrii HTCC2633
Length = 407
Score = 55.2 bits (127), Expect = 2e-06
Identities = 37/137 (27%), Positives = 58/137 (42%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
+ +D+ +A ++GV V NAP AN S ELT +++L R + A++ G W +
Sbjct: 83 NQVDLVAAAERGVPVFNAPFANTRSVAELTMASVIMLMRRIPEKMFAIQRGEWLKTADGA 142
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
+E+ K L I+G G A+ L A + P +
Sbjct: 143 NEVRKKKLGIIGYGNIGAQ--LSVIASALGMHVYYYDIAPKLAHGNARPMDTLDDILTEC 200
Query: 647 DYITLHTPLIESTRNFI 697
D +TLH P T+N I
Sbjct: 201 DVVTLHVPSTPRTKNMI 217
>UniRef50_A2SRM1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Methanocorpusculum
labreanum Z|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Methanocorpusculum
labreanum (strain ATCC 43576 / DSM 4855 / Z)
Length = 334
Score = 55.2 bits (127), Expect = 2e-06
Identities = 35/140 (25%), Positives = 59/140 (42%), Gaps = 1/140 (0%)
Frame = +2
Query: 293 IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSE 472
+DV +A K + V N P AN+L+ E T L+L L + + + K+G W + Y +
Sbjct: 93 VDVPAAKKHNIAVTNVPHANSLAVSEFTVALILTLMKKIPIMNKETKSGLWHK--YISQD 150
Query: 473 LAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRW-SWRTFGLLAD 649
++ KT+ I+G+G + ++ L+D
Sbjct: 151 VSDKTIGIVGMGSIGRLVAKKMYYGFGCKILYYSRTRESDIEQELDAKFVELHDLCRLSD 210
Query: 650 YITLHTPLIESTRNFINARC 709
ITLH P TR+ I+ +C
Sbjct: 211 VITLHLPYTSETRHIIDEKC 230
>UniRef50_Q1LCR9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Ralstonia metallidurans
CH34|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Ralstonia metallidurans (strain CH34 /
ATCC 43123 / DSM 2839)
Length = 317
Score = 54.8 bits (126), Expect = 2e-06
Identities = 39/142 (27%), Positives = 60/142 (42%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
+NI+ D+A +GV V +AP N+ + +ML +R + LKAG+WD
Sbjct: 81 ENIERDAARMRGVRVCHAPDTNSQVVADHALAMMLAWSRGIAMLDRGLKAGQWDALRAPR 140
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
+ GKTL I+GLG R L P+ P R+ +
Sbjct: 141 PGVRGKTLGIVGLGNIGQR--LAALAEAVGMRVAYLRRSGALQPNR-TPYGDVRSLAAAS 197
Query: 647 DYITLHTPLIESTRNFINARCL 712
D + L P +TR+ ++A L
Sbjct: 198 DVLALTCPGGPATRHLVDAEVL 219
>UniRef50_Q031D4 Cluster: Phosphoglycerate dehydrogenase; n=20;
Streptococcaceae|Rep: Phosphoglycerate dehydrogenase -
Lactococcus lactis subsp. cremoris (strain SK11)
Length = 398
Score = 54.8 bits (126), Expect = 2e-06
Identities = 41/152 (26%), Positives = 68/152 (44%), Gaps = 14/152 (9%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW-DRAL-- 457
+NI ++ KG+ V NAPG NA + EL ++M+ R++ PA+ L + D+A+
Sbjct: 64 NNIPIEKCASKGIVVFNAPGGNANAVKELVLSMMIFGTRNLKPANKWLTGQKGNDKAIDV 123
Query: 458 --------YTGSELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXA---PSS 604
++GSE++GKTL ++GLG ++ A
Sbjct: 124 AVENGKKAFSGSEISGKTLGVIGLGNIGSKVANDAQRLGMKVIGYDPYLSIEHAWNLSHH 183
Query: 605 IAPRWSWRTFGLLADYITLHTPLIESTRNFIN 700
+ ADYIT+HTP + T+ +N
Sbjct: 184 VKRVNDLSEIFEKADYITVHTPATDETKGMLN 215
>UniRef50_A0VQR0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Dinoroseobacter shibae
DFL 12|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Dinoroseobacter shibae DFL
12
Length = 316
Score = 54.8 bits (126), Expect = 2e-06
Identities = 41/143 (28%), Positives = 57/143 (39%), Gaps = 1/143 (0%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA-LYT 463
DNID+ + +G+ V A GAN S E T L+L R ++ ++ G W R L
Sbjct: 78 DNIDMAACAARGISVHPATGANTRSVAEYVITAALMLTRRAFMSTPEMQEGAWPRGPLGE 137
Query: 464 GSELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLL 643
G E+AG+ L + G G A + R S
Sbjct: 138 GGEIAGRKLGLYGCGAVAQAVARLAKPLSMTILGHDPHLGPGHPLWTEVTRVSDAELLAR 197
Query: 644 ADYITLHTPLIESTRNFINARCL 712
AD ++LH PL TR I+A L
Sbjct: 198 ADVLSLHLPLTPETRGRIDATAL 220
>UniRef50_Q83AZ4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=11; Bacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Coxiella burnetii
Length = 388
Score = 54.4 bits (125), Expect = 3e-06
Identities = 45/156 (28%), Positives = 65/156 (41%), Gaps = 14/156 (8%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPA-----------STALK 433
+NI V GV V+N PGANA + EL T +L+ +RH+ PA T
Sbjct: 63 NNIPVRPLTLSGVPVLNTPGANANAVKELVITGILLASRHIYPALDYARHIEGDDETITH 122
Query: 434 AGRWDRALYTGSELAGKTLAILGLGG---SAARWPLGCXXXXXXXXXXXXXXXXXXAPSS 604
++ ++G EL GKTL I+GLG A + S
Sbjct: 123 QVEKNKKRFSGFELPGKTLGIIGLGQIGVKVANAAIRLGMKAIGYDPAITVRSAWELSSE 182
Query: 605 IAPRWSWRTFGLLADYITLHTPLIESTRNFINARCL 712
+A S R +D++T+H PL T + IN +
Sbjct: 183 VAQAESLRDVLRNSDFVTVHVPLNTHTHHLINEEAI 218
>UniRef50_Q214B1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding precursor; n=2;
Proteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding precursor - Rhodopseudomonas
palustris (strain BisB18)
Length = 336
Score = 54.4 bits (125), Expect = 3e-06
Identities = 39/143 (27%), Positives = 60/143 (41%), Gaps = 1/143 (0%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
D +D+ +A K GV V+NAP AN+ S EL ML +R+ + + L T
Sbjct: 96 DTVDLAAAKKHGVTVLNAPLANSTSVAELALFYMLHCSRNFRLVQQTMLVDYYKAKLDTP 155
Query: 467 -SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLL 643
SE+A K L ++G+G +R P + +
Sbjct: 156 KSEIACKKLGLIGVGNIGSRVAKMARGFDMQVIGFDPYKTQADMPEGVELTQDFDRIFTD 215
Query: 644 ADYITLHTPLIESTRNFINARCL 712
D+++LH P T+ F+NAR L
Sbjct: 216 CDFVSLHCPSTPETKGFVNARQL 238
>UniRef50_Q0W672 Cluster: Glycerate dehydrogenase; n=2; Archaea|Rep:
Glycerate dehydrogenase - Uncultured methanogenic
archaeon RC-I
Length = 319
Score = 54.4 bits (125), Expect = 3e-06
Identities = 26/74 (35%), Positives = 42/74 (56%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
D++D+D+A KGV V NAPG + + E ++L R + A ++ ++D + G
Sbjct: 77 DDVDLDAATLKGVAVANAPGYSNEAVAEHVFAMLLSFIRRISEADFWIREEKFDCTAFEG 136
Query: 467 SELAGKTLAILGLG 508
EL GKT+ I+G G
Sbjct: 137 RELRGKTMGIIGTG 150
>UniRef50_P0A9T3 Cluster: D-3-phosphoglycerate dehydrogenase; n=185;
Bacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Shigella flexneri
Length = 410
Score = 54.4 bits (125), Expect = 3e-06
Identities = 37/140 (26%), Positives = 59/140 (42%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
+ +D+D+A K+G+ V NAP +N S EL +L+L R V A+ G W++
Sbjct: 87 NQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGS 146
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
E GK L I+G G + LG + ++
Sbjct: 147 FEARGKKLGIIGYGHIGTQ--LGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMS 204
Query: 647 DYITLHTPLIESTRNFINAR 706
D ++LH P ST+N + A+
Sbjct: 205 DVVSLHVPENPSTKNMMGAK 224
>UniRef50_O34815 Cluster: YoaD; n=2; Bacillus|Rep: YoaD - Bacillus
subtilis
Length = 344
Score = 54.0 bits (124), Expect = 3e-06
Identities = 28/84 (33%), Positives = 43/84 (51%), Gaps = 6/84 (7%)
Frame = +2
Query: 290 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR------ 451
N+DV +A K+G+ V PG NA + E+ ++ RH ++ LK G WD
Sbjct: 94 NVDVAAASKRGIPVFYTPGRNAQAVAEMFIGNVISFLRHTSASNQWLKDGEWDSDYLQAY 153
Query: 452 ALYTGSELAGKTLAILGLGGSAAR 523
+ G+EL GKT+ ++G G R
Sbjct: 154 VKFKGNELTGKTVGMIGFGAVGQR 177
>UniRef50_Q3Y1E6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=1;
Enterococcus faecium DO|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Enterococcus faecium DO
Length = 386
Score = 54.0 bits (124), Expect = 3e-06
Identities = 41/147 (27%), Positives = 62/147 (42%), Gaps = 9/147 (6%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAS---------TALKAG 439
+ I+V+ A + G V+N PG NA + EL +L+ +R ++ AS L+
Sbjct: 61 NTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPIIEASRMVQTLTGPNILEQA 120
Query: 440 RWDRALYTGSELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRW 619
R+ Y G EL GKT+ +LGLG + L C A +
Sbjct: 121 ENKRSAYVGRELQGKTIGLLGLGAIGTKVALSC----YSLGMDVLGYSIRDAQLDYVRQA 176
Query: 620 SWRTFGLLADYITLHTPLIESTRNFIN 700
T +DYI + PL E T+ I+
Sbjct: 177 DLETVLSTSDYIVVMLPLTEDTKGLID 203
>UniRef50_Q1FF19 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=1;
Clostridium phytofermentans ISDg|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Clostridium phytofermentans ISDg
Length = 316
Score = 54.0 bits (124), Expect = 3e-06
Identities = 30/75 (40%), Positives = 43/75 (57%), Gaps = 1/75 (1%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 463
DNID+ A +G+ V P ANA S E T L+L A+++V A L+ G ++ R
Sbjct: 76 DNIDIAEATAQGIKVCYTPLANANSVAEHTIMLLLACAKNIVIADKELRQGNYEIRNQMP 135
Query: 464 GSELAGKTLAILGLG 508
G ++ GKTL I+G G
Sbjct: 136 GIDVFGKTLGIIGFG 150
>UniRef50_Q0FY56 Cluster: Putative phosphoglycerate dehydrogenase
protein; n=1; Fulvimarina pelagi HTCC2506|Rep: Putative
phosphoglycerate dehydrogenase protein - Fulvimarina
pelagi HTCC2506
Length = 322
Score = 54.0 bits (124), Expect = 3e-06
Identities = 30/78 (38%), Positives = 41/78 (52%), Gaps = 3/78 (3%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD--RALY 460
D I V +A + G+ V N P NA S E L++ LAR +V ++ W RA
Sbjct: 70 DFIPVQAASRLGIAVTNTPSVNAKSVAEHVFGLIICLARRIVENDAGIRRNEWHALRAAA 129
Query: 461 TGS-ELAGKTLAILGLGG 511
GS E+AGK L ++G GG
Sbjct: 130 PGSCEIAGKALGLIGYGG 147
>UniRef50_Q01W77 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Solibacter usitatus
Ellin6076|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Solibacter usitatus (strain
Ellin6076)
Length = 312
Score = 54.0 bits (124), Expect = 3e-06
Identities = 27/74 (36%), Positives = 39/74 (52%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
D++D+ +A + GV V N PG A S E T L+ +AR + A + G W+R
Sbjct: 83 DHVDLAAAARHGVTVANTPGVAARSIAEHTLALLFAVARQIPHMDAATRRGAWERG--QS 140
Query: 467 SELAGKTLAILGLG 508
EL GKT ++G G
Sbjct: 141 MELYGKTCGVIGYG 154
>UniRef50_Q5KE95 Cluster: Phosphoglycerate dehydrogenase; n=2;
Filobasidiella neoformans|Rep: Phosphoglycerate
dehydrogenase - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 316
Score = 54.0 bits (124), Expect = 3e-06
Identities = 44/148 (29%), Positives = 64/148 (43%), Gaps = 10/148 (6%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYT- 463
D+ID++ +KGV ++N PG N+ ELT +L L L R V L+AG ++
Sbjct: 112 DSIDIEGCKEKGVTLMNCPGENSQVVAELTLSLTLALLRRVPELDRRLRAGETMLSINNL 171
Query: 464 GSELAGKTLAILGLGGSAAR------WPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRW-- 619
G L GK + ++G+ +A R C PS P
Sbjct: 172 GRTLRGKVVGMVGISATARRAAAIFHHAFDCTIRTFSPTSPPTRWSPSH-PSGPLPHTRH 230
Query: 620 -SWRTFGLLADYITLHTPLIESTRNFIN 700
S + L D +TLH PL S+RN I+
Sbjct: 231 SSLSSMLPLIDILTLHCPLTPSSRNMIS 258
>UniRef50_Q6L245 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Thermoplasmatales|Rep: D-3-phosphoglycerate
dehydrogenase - Picrophilus torridus
Length = 299
Score = 54.0 bits (124), Expect = 3e-06
Identities = 28/74 (37%), Positives = 42/74 (56%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
D+IDVD A +KG+ ++ APG++ S ELT ++ AR ++ + D G
Sbjct: 76 DSIDVDYAQEKGIKIVYAPGSSTESVVELTVAFAVIAARQIIKGVENTRKN--DFTKLKG 133
Query: 467 SELAGKTLAILGLG 508
EL+GKTL I+G G
Sbjct: 134 IELSGKTLGIIGYG 147
Score = 33.5 bits (73), Expect = 5.2
Identities = 17/57 (29%), Positives = 33/57 (57%)
Frame = +3
Query: 72 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 242
+LI D V E L+ I+++ELL +I ++D ++VRS T++ ++++D
Sbjct: 5 ILICDPVDGIMIEKLSK-DFDIDNSPDITRDELLKKIGDYDIIIVRSRTKIDRDIID 60
>UniRef50_A0RUD3 Cluster: 2 lactate dehydrogenase; n=2;
Thermoprotei|Rep: 2 lactate dehydrogenase - Cenarchaeum
symbiosum
Length = 348
Score = 54.0 bits (124), Expect = 3e-06
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 4/83 (4%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL--- 457
D+IDV A +G+ V P + +LT LML L R V ++AGRW +
Sbjct: 113 DHIDVAHARGRGITVGYTPDVLTDATADLTMALMLDLLRRVTEGDRIIRAGRWRQIYGAD 172
Query: 458 -YTGSELAGKTLAILGLGGSAAR 523
Y G+++ GKTL ILG+G +R
Sbjct: 173 DYLGTDVGGKTLGILGMGRIGSR 195
>UniRef50_P40054 Cluster: D-3-phosphoglycerate dehydrogenase 1;
n=35; Eukaryota|Rep: D-3-phosphoglycerate dehydrogenase
1 - Saccharomyces cerevisiae (Baker's yeast)
Length = 469
Score = 54.0 bits (124), Expect = 3e-06
Identities = 26/74 (35%), Positives = 41/74 (55%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
+ +D+D A +G+ V N+P +N+ S EL ++ LAR + S L G W++
Sbjct: 134 NQVDLDYATSRGIAVFNSPFSNSRSVAELVIAEIISLARQLGDRSIELHTGTWNKVAARC 193
Query: 467 SELAGKTLAILGLG 508
E+ GKTL I+G G
Sbjct: 194 WEVRGKTLGIIGYG 207
>UniRef50_Q72KT6 Cluster: Glycerate dehydrogenase/glyoxylate
reductase; n=2; Thermus thermophilus|Rep: Glycerate
dehydrogenase/glyoxylate reductase - Thermus
thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Length = 338
Score = 53.6 bits (123), Expect = 5e-06
Identities = 38/142 (26%), Positives = 62/142 (43%), Gaps = 4/142 (2%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAG---RWDRAL 457
D++D+++A ++G+ V + PG + +LT L+L +AR VV + + G W L
Sbjct: 104 DHVDLEAARERGIRVTHTPGVLTEATADLTLALLLAVARRVVEGAAYARDGLWRAWHPEL 163
Query: 458 YTGSELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIA-PRWSWRTF 634
G +L G TL ++G+G +G P + P S
Sbjct: 164 LLGLDLQGLTLGLVGMG------RIGQAVAKRALAFGMRVVYHARTPKPLPYPFLSLEEL 217
Query: 635 GLLADYITLHTPLIESTRNFIN 700
AD ++LHTPL T +N
Sbjct: 218 LKEADVVSLHTPLTPETHRLLN 239
>UniRef50_A6GGA6 Cluster: Probable 2-hydroxyacid dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: Probable 2-hydroxyacid
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 327
Score = 53.6 bits (123), Expect = 5e-06
Identities = 42/146 (28%), Positives = 61/146 (41%), Gaps = 4/146 (2%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR---AL 457
DN+DV + + + V N PG + +L L+L AR++ AS + GRW
Sbjct: 85 DNVDVPACTARSIRVGNTPGVLTDATADLAMALLLSAARNLPAASLDAREGRWQTWSPTG 144
Query: 458 YTGSELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSI-APRWSWRTF 634
+ G EL G TL ++GLG + AP + A R
Sbjct: 145 WLGLELRGATLGVVGLGKIGL--AVAQRARAFGMDILYTRRSDAPAPPELGATRVELDAL 202
Query: 635 GLLADYITLHTPLIESTRNFINARCL 712
AD ++LH PL TR+ I+A L
Sbjct: 203 LARADVVSLHVPLRPDTRHLIDAAAL 228
>UniRef50_A6EBH4 Cluster: Phosphoglycerate dehydrogenase; n=1;
Pedobacter sp. BAL39|Rep: Phosphoglycerate dehydrogenase
- Pedobacter sp. BAL39
Length = 309
Score = 53.6 bits (123), Expect = 5e-06
Identities = 40/142 (28%), Positives = 57/142 (40%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNID A ++ + +INAP N + E LML L + A ++ G+WDR G
Sbjct: 78 DNIDEAVALERNIHLINAPEGNMDAVGEHAVGLMLSLMNNFRNADMEIRKGKWDREGNRG 137
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
EL GKT+ I+G G + L A S L+
Sbjct: 138 YELKGKTVGIIGYGFMGS--SLARKLSGFGVQVIAYDKYKTGFSDQYAREVSMEEIVKLS 195
Query: 647 DYITLHTPLIESTRNFINARCL 712
D ++ H PL TR ++ L
Sbjct: 196 DVLSFHIPLTNETRQLVDEEYL 217
>UniRef50_Q5FUW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=55;
Bacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Gluconobacter oxydans (Gluconobacter suboxydans)
Length = 416
Score = 53.2 bits (122), Expect = 6e-06
Identities = 26/74 (35%), Positives = 41/74 (55%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
+ +D+++A G+ V NAP +N S EL +++L R + S A G WD++
Sbjct: 88 NQVDLNAARMLGIPVFNAPFSNTRSVAELVMGEIVMLLRRIPSRSEACHKGGWDKSATNA 147
Query: 467 SELAGKTLAILGLG 508
E+ GKTL I+G G
Sbjct: 148 WEVRGKTLGIVGYG 161
>UniRef50_Q49ZM5 Cluster: Putative dehydrogenase; n=1;
Staphylococcus saprophyticus subsp. saprophyticus ATCC
15305|Rep: Putative dehydrogenase - Staphylococcus
saprophyticus subsp. saprophyticus (strain ATCC 15305
/DSM 20229)
Length = 318
Score = 53.2 bits (122), Expect = 6e-06
Identities = 29/82 (35%), Positives = 45/82 (54%), Gaps = 5/82 (6%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA---GRWDRAL 457
+N+D+D A ++ + V N P A+ S ELT L+L +AR + + W
Sbjct: 79 NNVDIDYARQQNIDVTNTPKASTNSTAELTFALVLAVARRIPEGDKLCRTTGFDGWAPLF 138
Query: 458 YTGSELAGKTLAILGLG--GSA 517
+ G E++GKT+ I+GLG GSA
Sbjct: 139 FRGREVSGKTIGIIGLGEIGSA 160
>UniRef50_A7IJ69 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=2; Rhizobiales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Xanthobacter sp. (strain Py2)
Length = 359
Score = 53.2 bits (122), Expect = 6e-06
Identities = 43/145 (29%), Positives = 64/145 (44%), Gaps = 3/145 (2%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
D +DVD+A G V A GAN + + T LML + R + + A+ G W R L G
Sbjct: 116 DRVDVDAARDLGRVVTIAAGANDPAVADHTIALMLAVLRRLKASQAAIARGDW-RVL-VG 173
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLL- 643
++L GKT+ ++G G +G P A ++ L
Sbjct: 174 ADLTGKTVGLIGFG------RIGRQVARRLSGFDVTVLVTSRTPDPEAAGVTFVALDELI 227
Query: 644 --ADYITLHTPLIESTRNFINARCL 712
+D ++LH PL+ TR+ INA L
Sbjct: 228 ARSDVVSLHAPLVPETRHVINAATL 252
>UniRef50_Q8Y3L1 Cluster: Lmo2824 protein; n=14; Bacillales|Rep:
Lmo2824 protein - Listeria monocytogenes
Length = 395
Score = 52.8 bits (121), Expect = 8e-06
Identities = 42/155 (27%), Positives = 62/155 (40%), Gaps = 13/155 (8%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALK----------A 436
+NI V++ +KG+ V N PGANA + EL + V AR ++ + +K
Sbjct: 61 NNIPVENCSEKGIVVFNTPGANANAVKELVLASLFVSARPILEGTEWVKELPAEDDVEQK 120
Query: 437 GRWDRALYTGSELAGKTLAILGL---GGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSI 607
+ + G+ELAGK L I+GL G A L +
Sbjct: 121 VEAGKKAFAGTELAGKKLGIIGLGAIGALVANDALSLGMDVVGYDPFVSVDTAWRISKEV 180
Query: 608 APRWSWRTFGLLADYITLHTPLIESTRNFINARCL 712
+ DY+T+H PL + TR NA L
Sbjct: 181 ERAMTIEEVLATCDYLTVHVPLTDKTRGMFNADTL 215
>UniRef50_Q88ZU6 Cluster: Phosphoglycerate dehydrogenase; n=2;
Lactobacillus|Rep: Phosphoglycerate dehydrogenase -
Lactobacillus plantarum
Length = 392
Score = 52.8 bits (121), Expect = 8e-06
Identities = 29/83 (34%), Positives = 46/83 (55%), Gaps = 9/83 (10%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST---------ALKAG 439
+NI +D A G V N PG+NA + EL L+++ +R+++ A+T +
Sbjct: 60 NNIPIDQATANGTAVFNTPGSNANAVKELIIGLLIMASRNLIAATTYSAQHTEADISQRT 119
Query: 440 RWDRALYTGSELAGKTLAILGLG 508
D+ + G EL GKTLA++GLG
Sbjct: 120 EHDKTQFNGIELTGKTLAVIGLG 142
Score = 34.7 bits (76), Expect = 2.3
Identities = 14/26 (53%), Positives = 19/26 (73%)
Frame = +1
Query: 511 VGREVATRMYAFGMNIIGFDPFVSAD 588
VG VA + GMN+IG+DP++SAD
Sbjct: 144 VGALVANAALSLGMNVIGYDPYLSAD 169
>UniRef50_Q6AMI7 Cluster: Related to D-3-phosphoglycerate
dehydrogenase; n=1; Desulfotalea psychrophila|Rep:
Related to D-3-phosphoglycerate dehydrogenase -
Desulfotalea psychrophila
Length = 393
Score = 52.8 bits (121), Expect = 8e-06
Identities = 46/158 (29%), Positives = 71/158 (44%), Gaps = 16/158 (10%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHV------VPASTALKAGRWD 448
+N++V+ A KKG+ V N PGANA + +L ++ V R++ + TA+ + D
Sbjct: 62 NNVNVERATKKGICVFNTPGANANAVVDLVFPMLGVWKRNIFNGINFCKSLTAVDPDKVD 121
Query: 449 ------RALYTGSELAGKTLAILGLGGSAARWPLG----CXXXXXXXXXXXXXXXXXXAP 598
++ Y G E+AGK L ++GLG R G +P
Sbjct: 122 SVVEAQKSAYKGEEIAGKNLTVVGLGQIGVRLANGGIQRLMNVKGFDPAPALENIHQLSP 181
Query: 599 SSIAPRWSWRTFGLLADYITLHTPLIESTRNFINARCL 712
R + + AD I+LH PL + TRN +NA L
Sbjct: 182 QVRVCR-ALKDAVSDADVISLHLPLNDRTRNLVNAEFL 218
>UniRef50_A1AQ02 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=3; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Pelobacter propionicus (strain DSM 2379)
Length = 318
Score = 52.8 bits (121), Expect = 8e-06
Identities = 42/146 (28%), Positives = 64/146 (43%), Gaps = 4/146 (2%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD---RAL 457
+NID+ +A +G+GV N P + + +L T ML L+ +V T L+ G D ++L
Sbjct: 80 NNIDIAAARSRGIGVCNVPSYSTDAVAQLAITFMLNLSASLVQQQTMLRRGNLDNFQKSL 139
Query: 458 YTGS-ELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTF 634
EL GKTL ++G G R P S
Sbjct: 140 QLPHFELNGKTLGVIGFGEIGRRVIAIARTLGMKIIVHSRTPRPELDPD--LRFVSLEEL 197
Query: 635 GLLADYITLHTPLIESTRNFINARCL 712
+D+++LH PL ++TR+ INA L
Sbjct: 198 LATSDFVSLHCPLNDATRHVINAERL 223
>UniRef50_Q4WMF4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=21; Pezizomycotina|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Aspergillus fumigatus (Sartorya fumigata)
Length = 343
Score = 52.8 bits (121), Expect = 8e-06
Identities = 33/82 (40%), Positives = 47/82 (57%), Gaps = 4/82 (4%)
Frame = +2
Query: 290 NIDVDSAGKKGVGVINA----PGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL 457
++D+ + +G+ V PG N S + T L+L LARHV A+KAG+W +L
Sbjct: 89 SLDLPALTARGIPVAGTVGRPPGVN--STVQHTWALILALARHVARDDAAVKAGKWQGSL 146
Query: 458 YTGSELAGKTLAILGLGGSAAR 523
G L+GKTLA+LGLG A+
Sbjct: 147 --GVNLSGKTLALLGLGKLGAQ 166
>UniRef50_Q8TR50 Cluster: Glycerate dehydrogenase; n=2;
Methanosarcina|Rep: Glycerate dehydrogenase -
Methanosarcina acetivorans
Length = 319
Score = 52.8 bits (121), Expect = 8e-06
Identities = 41/140 (29%), Positives = 54/140 (38%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DN+D++ A GV V N P S E L L L R V A L+ G +D Y G
Sbjct: 77 DNVDLEEATDHGVIVSNVPSYAFESVAEFVFALTLNLLRRVHLADMNLREGLFDWKYYVG 136
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
++L KT+ +LG G R A + T +
Sbjct: 137 NQLMSKTIGVLGTGEIGKRVIQIAHGFNMNVLSVTAHPSPERAKALGVKFVDLDTLLSES 196
Query: 647 DYITLHTPLIESTRNFINAR 706
D +TLH PL T + I AR
Sbjct: 197 DIVTLHVPLTPETEHMIGAR 216
>UniRef50_Q88YI0 Cluster: Phosphoglycerate dehydrogenase; n=5;
Bacilli|Rep: Phosphoglycerate dehydrogenase -
Lactobacillus plantarum
Length = 324
Score = 52.4 bits (120), Expect = 1e-05
Identities = 27/77 (35%), Positives = 41/77 (53%), Gaps = 3/77 (3%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA---GRWDRAL 457
+NID+ +A K+ + V N P +A++ E T L++ LA +V ++ W
Sbjct: 79 NNIDIAAAAKRQIPVTNTPNVSAVATAESTVGLIISLAHRIVEGDHLMRTSGFNGWAPLF 138
Query: 458 YTGSELAGKTLAILGLG 508
+ G L GKTL ILGLG
Sbjct: 139 FLGHNLQGKTLGILGLG 155
>UniRef50_Q4AIL7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding precursor; n=1;
Chlorobium phaeobacteroides BS1|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding
precursor - Chlorobium phaeobacteroides BS1
Length = 312
Score = 52.4 bits (120), Expect = 1e-05
Identities = 27/78 (34%), Positives = 41/78 (52%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
+NID+ SA K V +NAP N + E ++L L ++ A ++ G W R G
Sbjct: 78 ENIDIQSADKHQVVCLNAPEGNRDAVAEQAVGMILTLFNRLLIADAEVRKGIWLREQNRG 137
Query: 467 SELAGKTLAILGLGGSAA 520
EL GKT+ I+G G + +
Sbjct: 138 IELGGKTVGIIGYGNTGS 155
>UniRef50_Q03YV3 Cluster: Lactate dehydrogenase related enzyme; n=1;
Leuconostoc mesenteroides subsp. mesenteroides ATCC
8293|Rep: Lactate dehydrogenase related enzyme -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 314
Score = 52.4 bits (120), Expect = 1e-05
Identities = 25/75 (33%), Positives = 45/75 (60%), Gaps = 1/75 (1%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 463
D +DVD+A ++G+ V+N P A + S E + +L +++++ S A+ W+ R +
Sbjct: 76 DAVDVDAATQRGIYVVNTPKALSGSVAETAVSELLAISKNLYQDSKAIHDDNWNYRKAHP 135
Query: 464 GSELAGKTLAILGLG 508
G ++ GKT+ ILG G
Sbjct: 136 GRDIEGKTVGILGFG 150
>UniRef50_A6T665 Cluster: Putative D-3-phosphoglycerate
dehydrogenase; n=1; Klebsiella pneumoniae subsp.
pneumoniae MGH 78578|Rep: Putative D-3-phosphoglycerate
dehydrogenase - Klebsiella pneumoniae subsp. pneumoniae
MGH 78578
Length = 342
Score = 52.4 bits (120), Expect = 1e-05
Identities = 26/55 (47%), Positives = 35/55 (63%)
Frame = +2
Query: 290 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 454
NID +A +G+ V+ PG NA +A ELT LML LARH+ + ALK G + +A
Sbjct: 79 NIDTQAAQARGIRVLYTPGRNADAAAELTLGLMLSLARHIPQSHAALKRGEFTQA 133
>UniRef50_A1JTE6 Cluster: Putative oxidoreductase; n=1; Yersinia
enterocolitica subsp. enterocolitica 8081|Rep: Putative
oxidoreductase - Yersinia enterocolitica serotype O:8 /
biotype 1B (strain 8081)
Length = 338
Score = 52.4 bits (120), Expect = 1e-05
Identities = 25/48 (52%), Positives = 35/48 (72%)
Frame = +2
Query: 290 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALK 433
NIDV++A ++G+ V+ PG N+ +A ELT LML LARH+ A +ALK
Sbjct: 79 NIDVNAATERGIPVVYTPGRNSDAAAELTIALMLNLARHIPQAHSALK 126
>UniRef50_Q65WI5 Cluster: SerA protein; n=1; Mannheimia
succiniciproducens MBEL55E|Rep: SerA protein -
Mannheimia succiniciproducens (strain MBEL55E)
Length = 326
Score = 52.0 bits (119), Expect = 1e-05
Identities = 27/75 (36%), Positives = 43/75 (57%), Gaps = 1/75 (1%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 463
D++DV +A + G+ V+ APG+N S E LM A+ +V + ++ G + R+ Y
Sbjct: 76 DDVDVKTATELGIPVVIAPGSNTRSVAEHAFALMFACAKDIVRSDNEMRKGNFAIRSSYK 135
Query: 464 GSELAGKTLAILGLG 508
EL KTLA++G G
Sbjct: 136 AYELNHKTLALIGYG 150
>UniRef50_Q2S4U0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding domain protein; n=2; cellular
organisms|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding domain protein - Salinibacter
ruber (strain DSM 13855)
Length = 321
Score = 52.0 bits (119), Expect = 1e-05
Identities = 34/89 (38%), Positives = 48/89 (53%), Gaps = 6/89 (6%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAG---RWDRAL 457
DNID+++A V V + PG + + L+L ARHV A ++ G RW+
Sbjct: 80 DNIDLEAAEAHDVAVTHTPGVLTDATADQAWALLLAAARHVPAADRYVRDGRFERWETTH 139
Query: 458 YTGSELAGKTLAILGLG--GSA-ARWPLG 535
G ELA KT+ I+G+G G+A AR LG
Sbjct: 140 LMGMELARKTIGIVGMGRIGTAVARRALG 168
>UniRef50_A6CRV0 Cluster: 2-hydroxyacid dehydrogenase; n=15;
Bacillales|Rep: 2-hydroxyacid dehydrogenase - Bacillus
sp. SG-1
Length = 351
Score = 52.0 bits (119), Expect = 1e-05
Identities = 26/77 (33%), Positives = 43/77 (55%), Gaps = 3/77 (3%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRAL 457
DNID+ +A +K V V N P + +LT LM+ AR ++ A ++ G+ W L
Sbjct: 106 DNIDLKAANEKDVAVCNTPDVLTDTTADLTFGLMMAAARRLIEADKYVREGKWKSWSPLL 165
Query: 458 YTGSELAGKTLAILGLG 508
G+++ KT+ I+G+G
Sbjct: 166 MAGTDIHHKTVGIIGMG 182
>UniRef50_A3ZW64 Cluster: Phosphoglycerate dehydrogenase, putative;
n=1; Blastopirellula marina DSM 3645|Rep:
Phosphoglycerate dehydrogenase, putative -
Blastopirellula marina DSM 3645
Length = 320
Score = 52.0 bits (119), Expect = 1e-05
Identities = 37/142 (26%), Positives = 60/142 (42%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
D+++V +A ++ + V PG S E T ++L + R+V+ + ++AG WDR G
Sbjct: 77 DSVNVPAATEQNIAVCRTPGTLHQSVVEHTIGMILAIYRNVISQNKQVRAGDWDRT--AG 134
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
GKTL I+G G + PS + R + +
Sbjct: 135 PRAYGKTLGIIGY-GVIGKEVAKAAVLLGMQVIAYDPIAPAGGPSEV-ERVALDEIWRRS 192
Query: 647 DYITLHTPLIESTRNFINARCL 712
D ++LH P T INA+ L
Sbjct: 193 DVVSLHAPCTPETERIINAQSL 214
>UniRef50_A3K878 Cluster: 2-hydroxyacid dehydrogenase; n=1;
Sagittula stellata E-37|Rep: 2-hydroxyacid dehydrogenase
- Sagittula stellata E-37
Length = 314
Score = 52.0 bits (119), Expect = 1e-05
Identities = 29/76 (38%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR--ALY 460
D +DV++A + GV V N P E+T LML LA V + ++ GRW+ A+
Sbjct: 79 DAVDVEAAKEHGVRVTNTPDVLNDCVAEVTLALMLALAHRVPESHAYVRDGRWETEGAMP 138
Query: 461 TGSELAGKTLAILGLG 508
+EL G T+ I+GLG
Sbjct: 139 LTAELTGATVGIIGLG 154
>UniRef50_A0JWH0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=14; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Arthrobacter sp. (strain FB24)
Length = 322
Score = 52.0 bits (119), Expect = 1e-05
Identities = 31/73 (42%), Positives = 44/73 (60%)
Frame = +2
Query: 290 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGS 469
+ID+ +A + G+ V+ G + +A ELT L+L LAR + L+ GRW + G
Sbjct: 84 SIDLRAAEELGI-VVCGTGGSPTAAPELTWGLLLALARSISFEDRNLREGRWQSTV--GF 140
Query: 470 ELAGKTLAILGLG 508
ELAGKTL +LGLG
Sbjct: 141 ELAGKTLGVLGLG 153
Score = 33.9 bits (74), Expect = 4.0
Identities = 15/46 (32%), Positives = 27/46 (58%)
Frame = +1
Query: 508 RVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPSS 645
++GR VA AFGM++I + P ++ + AQ K+ E+++ S
Sbjct: 154 KIGRRVAAYGQAFGMDVIAWSPNLTGEAAAQAGVRKVSKEELFRDS 199
>UniRef50_A0GVM6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Burkholderia
phytofirmans PsJN|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Burkholderia phytofirmans
PsJN
Length = 327
Score = 52.0 bits (119), Expect = 1e-05
Identities = 39/143 (27%), Positives = 59/143 (41%), Gaps = 1/143 (0%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW-DRALYT 463
D I V+ A + + V N P +N + E +L +AR A + W R +
Sbjct: 76 DFIPVERATRADIAVANLPDSNTQAVAEHVVGAILAMARGFDRLPRAWRNDGWLVRQTFQ 135
Query: 464 GSELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLL 643
G EL +T+ I+GLG + PS + F
Sbjct: 136 GIELRDRTVGIVGLGRIGLQVAAALHHGFGMRVLGCDNGAREGLPSYVDQTSIENVFSG- 194
Query: 644 ADYITLHTPLIESTRNFINARCL 712
+D+ITLH PL++STR+ +NA L
Sbjct: 195 SDFITLHAPLVKSTRHLVNAELL 217
>UniRef50_Q8R8Q2 Cluster: Lactate dehydrogenase and related
dehydrogenases; n=8; cellular organisms|Rep: Lactate
dehydrogenase and related dehydrogenases -
Thermoanaerobacter tengcongensis
Length = 358
Score = 51.6 bits (118), Expect = 2e-05
Identities = 32/81 (39%), Positives = 44/81 (54%), Gaps = 2/81 (2%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSA-CELTCTLMLVLARHVVPASTALKAGRW-DRALY 460
D ID++SA KKG V G A E L+L + R V AS +K G+W +RA +
Sbjct: 106 DAIDIESATKKGTIVTIVEGIVEREAVAENAVALLLDVMRKVREASIKVKEGKWHERANF 165
Query: 461 TGSELAGKTLAILGLGGSAAR 523
G E+ GKT I+G+G +R
Sbjct: 166 IGYEIKGKTAGIIGIGNIGSR 186
>UniRef50_Q82U25 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=3; Nitrosomonadaceae|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Nitrosomonas
europaea
Length = 311
Score = 51.6 bits (118), Expect = 2e-05
Identities = 40/142 (28%), Positives = 61/142 (42%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DN+D+++A + + V N P A A + ELT LML R + +++ G W R+ G
Sbjct: 83 DNVDLEAARRLNIQVSNTPEAPAQAVAELTLGLMLDCLRQINRIDRSVRQGEWPRS--QG 140
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
LA +T+ I+GLG R C AP + + T A
Sbjct: 141 RLLAARTVGIVGLGHIGRRVAKLC--QAFGAQVIAHDPHLQLAPDGV-ELVALTTLLEQA 197
Query: 647 DYITLHTPLIESTRNFINARCL 712
D +TLH P + I+A +
Sbjct: 198 DLVTLHLPYSPAVHYLIDAEAI 219
>UniRef50_Q5FUD9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Gluconobacter oxydans|Rep: D-3-phosphoglycerate
dehydrogenase - Gluconobacter oxydans (Gluconobacter
suboxydans)
Length = 314
Score = 51.6 bits (118), Expect = 2e-05
Identities = 27/72 (37%), Positives = 40/72 (55%), Gaps = 1/72 (1%)
Frame = +2
Query: 305 SAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYTGSELAG 481
+A +GV V NAP N+ S E+T L+L + R + A A++ G W+ R G EL
Sbjct: 81 AAAARGVLVTNAPNTNSRSVAEMTIGLLLAVVRRLCEADLAVREGNWEFRYTGKGMELHT 140
Query: 482 KTLAILGLGGSA 517
+TL ++G G A
Sbjct: 141 RTLGLVGFGAIA 152
>UniRef50_Q30V14 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=3; Desulfovibrio|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Desulfovibrio desulfuricans (strain G20)
Length = 305
Score = 51.6 bits (118), Expect = 2e-05
Identities = 27/74 (36%), Positives = 41/74 (55%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DN+D+++A +G+ V N P + ELT L L L R V L++G W + + G
Sbjct: 81 DNVDMEAARARGIAVRNTPDGPTQAVAELTLGLALDLMRQVSRMDRELRSGVWKKRM--G 138
Query: 467 SELAGKTLAILGLG 508
+ L GK L I+G+G
Sbjct: 139 NLLGGKRLGIVGMG 152
>UniRef50_A6LZ51 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Clostridium
beijerinckii NCIMB 8052|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Clostridium
beijerinckii NCIMB 8052
Length = 320
Score = 51.6 bits (118), Expect = 2e-05
Identities = 36/139 (25%), Positives = 59/139 (42%), Gaps = 1/139 (0%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL-YT 463
DN+D+D+ + G+ NA G NA + E L+L +++ + +K + L YT
Sbjct: 80 DNVDIDACTQYGIWAANAAGVNAQAVAEHVMALILSYYKNIPFLDSFIKNKIDENELQYT 139
Query: 464 GSELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLL 643
GSEL GKT+ I+G G + C S + T
Sbjct: 140 GSELKGKTIGIIGFGAVGKKVAEFC--RVFDMNILVYARNPVVQSDSFVKMTDFDTLVGA 197
Query: 644 ADYITLHTPLIESTRNFIN 700
+D +++H L + T+ IN
Sbjct: 198 SDIVSVHVSLNQQTKQLIN 216
>UniRef50_A4FK85 Cluster: D-3-phosphoglycerate dehydrogenase,
putative; n=1; Saccharopolyspora erythraea NRRL
2338|Rep: D-3-phosphoglycerate dehydrogenase, putative -
Saccharopolyspora erythraea (strain NRRL 23338)
Length = 352
Score = 51.6 bits (118), Expect = 2e-05
Identities = 28/77 (36%), Positives = 40/77 (51%), Gaps = 4/77 (5%)
Frame = +2
Query: 290 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY--- 460
N+D+ +A + GV V APG NA +A E L+L R + + LK+G W Y
Sbjct: 100 NVDLQAATEAGVVVSYAPGRNAAAAAEFAVGLVLAALRRIPASDAELKSGNWRGDYYAYE 159
Query: 461 -TGSELAGKTLAILGLG 508
G EL G T+ ++G G
Sbjct: 160 NAGIELEGSTVGLVGYG 176
>UniRef50_A4AN91 Cluster: Predicted dehydrogenase; n=14;
Bacteroidetes|Rep: Predicted dehydrogenase -
Flavobacteriales bacterium HTCC2170
Length = 337
Score = 51.6 bits (118), Expect = 2e-05
Identities = 28/74 (37%), Positives = 42/74 (56%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
+NIDV A KK + + AP N + E T ++L L ++ A+ ++ G+WDR G
Sbjct: 100 ENIDVAYAKKKNIFLAAAPEGNRNAVGEHTLGMLLSLFNNLNKANLEVRNGKWDREGNRG 159
Query: 467 SELAGKTLAILGLG 508
EL GKT+ I+G G
Sbjct: 160 VELDGKTVGIIGYG 173
>UniRef50_A1RC54 Cluster: Glyoxylate reductase; n=2;
Actinomycetales|Rep: Glyoxylate reductase - Arthrobacter
aurescens (strain TC1)
Length = 329
Score = 51.6 bits (118), Expect = 2e-05
Identities = 40/152 (26%), Positives = 67/152 (44%), Gaps = 10/152 (6%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRAL 457
+NIDVD+A + G+ V N PG + ++ L+L AR VV + ++ G+ W+
Sbjct: 78 NNIDVDAATRHGILVGNTPGVLTDATADVAMLLILGTARRVVESDRVVRDGKFLGWEPEF 137
Query: 458 YTGSELAGKTLAILGLGGSA---ARWPLGCXXXXXXXXXXXXXXXXXXAP----SSIAPR 616
G +++G L + G G A AR LG + +
Sbjct: 138 MLGRDVSGAVLGLAGFGRIARAVARRALGFGMEELFSPRPPGDRPVSDEELGEFAGKVRQ 197
Query: 617 WSWRTFGLLADYITLHTPLIESTRNFINARCL 712
W + +D+++LH PL E TR+ ++A L
Sbjct: 198 VPWDSLVERSDFLSLHVPLNEQTRHLVDADVL 229
>UniRef50_Q6MY49 Cluster: NAD-dependant D-isomer specific
2-hydroxyacid dehydrogenase, putative; n=5;
Eurotiomycetidae|Rep: NAD-dependant D-isomer specific
2-hydroxyacid dehydrogenase, putative - Aspergillus
fumigatus (Sartorya fumigata)
Length = 335
Score = 51.6 bits (118), Expect = 2e-05
Identities = 26/75 (34%), Positives = 40/75 (53%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNID+ + +KG+ V + P A + ++ LM+ R +AL+AG+W G
Sbjct: 88 DNIDIPACSEKGIAVSSTPVAVNHATADVGIFLMIGALRQAYIPLSALRAGQWQGKTTLG 147
Query: 467 SELAGKTLAILGLGG 511
+ GK L ILG+GG
Sbjct: 148 HDPQGKVLGILGMGG 162
>UniRef50_Q986P2 Cluster: Phosphoglycerate dehydrogenase; n=14;
cellular organisms|Rep: Phosphoglycerate dehydrogenase -
Rhizobium loti (Mesorhizobium loti)
Length = 330
Score = 51.2 bits (117), Expect = 2e-05
Identities = 28/77 (36%), Positives = 40/77 (51%), Gaps = 4/77 (5%)
Frame = +2
Query: 290 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY--- 460
NID+ +A G+ V+N PG NA + E T +L R + AL+ G W LY
Sbjct: 90 NIDMAAARAHGITVVNVPGRNATAVAEFTLGAILAETRLIRVGHEALRKGEWRGDLYRAD 149
Query: 461 -TGSELAGKTLAILGLG 508
TG EL+ T+ ++G G
Sbjct: 150 RTGRELSEMTVGVIGYG 166
>UniRef50_Q82XE1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=5; Proteobacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Nitrosomonas
europaea
Length = 403
Score = 51.2 bits (117), Expect = 2e-05
Identities = 40/152 (26%), Positives = 66/152 (43%), Gaps = 14/152 (9%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD------ 448
+NI V+ +G+ V N PGANA + EL ML+ +R+++PA ++ D
Sbjct: 69 NNIPVNQMSARGIPVFNTPGANANAVRELVLAGMLMASRNLIPALRFVETLEGDDQSFNL 128
Query: 449 -----RALYTGSELAGKTLAILGL---GGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSS 604
+ ++G EL G+TL ++GL G A + P+
Sbjct: 129 QVEAGKKQFSGLELPGRTLGVIGLGKIGRQVADIAIKLGMKVLGYDPKITIDSAWSLPAE 188
Query: 605 IAPRWSWRTFGLLADYITLHTPLIESTRNFIN 700
+ + +I+LH PL +STR+ IN
Sbjct: 189 VQKANQIEDLIRRSQFISLHVPLNDSTRHLIN 220
>UniRef50_Q7WEA3 Cluster: Phosphoglycerate dehydrogenase; n=1;
Bordetella bronchiseptica|Rep: Phosphoglycerate
dehydrogenase - Bordetella bronchiseptica (Alcaligenes
bronchisepticus)
Length = 329
Score = 51.2 bits (117), Expect = 2e-05
Identities = 46/151 (30%), Positives = 62/151 (41%), Gaps = 9/151 (5%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW----DRA 454
D I V A G+ V+ P AN S E LMLV AR V A A + G W ++
Sbjct: 74 DKIAVAHADALGIPVVYTPQANVRSVAEHALMLMLVTARQAVQADAATRKGHWGFKYEQP 133
Query: 455 LYTGSELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTF 634
+Y+ L GKTL ++GLG + L C P + R
Sbjct: 134 MYS---LYGKTLGVIGLGRTGR---LLCEMAAPALNMQALVWSPSLPAGEALPPGARRVD 187
Query: 635 GLL-----ADYITLHTPLIESTRNFINARCL 712
L AD ++LH PL TR+ ++A L
Sbjct: 188 TLQELLREADVVSLHRPLRPDTRHTLDAATL 218
>UniRef50_Q74CK1 Cluster: Glycerate dehydrogenase; n=12;
Bacteria|Rep: Glycerate dehydrogenase - Geobacter
sulfurreducens
Length = 327
Score = 51.2 bits (117), Expect = 2e-05
Identities = 31/80 (38%), Positives = 45/80 (56%), Gaps = 6/80 (7%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW----DRA 454
+N+DV++AGK+G+ V N P + S + T L+L LA HV +A+KA W D +
Sbjct: 81 NNVDVEAAGKRGIPVANIPAYSTESVVQTTFALLLELAVHVGIHDSAVKAREWVRSPDHS 140
Query: 455 LYTGS--ELAGKTLAILGLG 508
+ EL G TL I+G G
Sbjct: 141 FWKTPIVELDGLTLGIVGYG 160
>UniRef50_Q4IV69 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic domain:D- isomer specific
2-hydroxyacid dehydrogenase, NAD binding domain; n=1;
Azotobacter vinelandii AvOP|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic domain:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD binding domain
- Azotobacter vinelandii AvOP
Length = 319
Score = 51.2 bits (117), Expect = 2e-05
Identities = 29/78 (37%), Positives = 42/78 (53%), Gaps = 4/78 (5%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD----RA 454
D ID+D A ++G+ V N+P ANA S +L L++ R++ A L+AGRW
Sbjct: 81 DGIDLDHARQRGIVVTNSPAANAASVADLAMGLLISSVRNLPAARQYLEAGRWQGNAGER 140
Query: 455 LYTGSELAGKTLAILGLG 508
+ L G+ L I GLG
Sbjct: 141 MPPVRGLGGRRLGICGLG 158
>UniRef50_Q1WVK4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Lactobacillus salivarius subsp. salivarius UCC118|Rep:
D-3-phosphoglycerate dehydrogenase - Lactobacillus
salivarius subsp. salivarius (strain UCC118)
Length = 394
Score = 51.2 bits (117), Expect = 2e-05
Identities = 45/149 (30%), Positives = 64/149 (42%), Gaps = 12/149 (8%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHV-VPASTALKAGRWDRALYT 463
+NI ++ A +G V N PG+NA + EL T++L+ R V A K D +L T
Sbjct: 61 NNIPLEKATSQGTAVFNTPGSNANAVKELIITMLLLSVRPVFASVKWAQKLAGADVSLQT 120
Query: 464 --------GSELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXA--PSSIAP 613
G+EL GK + I+GLG +R C A S+ P
Sbjct: 121 EKGKNHFAGTELYGKKIGIIGLGNIGSRVAKACMDLGMKVIGYDPYISVEKAWQLSNDIP 180
Query: 614 R-WSWRTFGLLADYITLHTPLIESTRNFI 697
R S +D+IT+H P + RN I
Sbjct: 181 RAESLEELLEQSDFITIHIPYTDKNRNII 209
>UniRef50_A4S3N1 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 380
Score = 51.2 bits (117), Expect = 2e-05
Identities = 23/74 (31%), Positives = 40/74 (54%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DN+D + A ++G+ V+ P + LS E +M+ L RH+ + L+ G + G
Sbjct: 114 DNVDCERARERGISVLRVPAYDPLSISEHAVAMMMSLNRHLCASRDRLRMGNFTLDGLVG 173
Query: 467 SELAGKTLAILGLG 508
S + GKT+ ++G G
Sbjct: 174 SSMRGKTVGVVGTG 187
>UniRef50_Q27SS3 Cluster: Glycerate dehydrogenase-like protein; n=2;
Eukaryota|Rep: Glycerate dehydrogenase-like protein -
Trimastix pyriformis
Length = 232
Score = 51.2 bits (117), Expect = 2e-05
Identities = 29/77 (37%), Positives = 43/77 (55%), Gaps = 3/77 (3%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAG---RWDRAL 457
+NID+ +A ++ V V N P A + +LT L+L +AR +V ++AG W
Sbjct: 78 NNIDLTAANERHVVVTNTPHCLAEATADLTMGLLLAVARRLVEGDGLVRAGLFKGWAPEF 137
Query: 458 YTGSELAGKTLAILGLG 508
G +L GKTL I+GLG
Sbjct: 138 LLGMDLHGKTLGIIGLG 154
>UniRef50_Q9HVG5 Cluster: Glycerate dehydrogenase; n=23;
Gammaproteobacteria|Rep: Glycerate dehydrogenase -
Pseudomonas aeruginosa
Length = 323
Score = 50.8 bits (116), Expect = 3e-05
Identities = 43/149 (28%), Positives = 64/149 (42%), Gaps = 10/149 (6%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL--- 457
+NID+ +A ++G+ V N G S + T L+L LA + A+++GRW ++
Sbjct: 82 NNIDLAAARERGIVVANCHGYGTPSVAQHTLALLLALATRLPDYQQAVRSGRWQQSSQFC 141
Query: 458 ---YTGSELAGKTLAILG---LGGSAARWPLGCXXXXXXXXXXXXXXXXXXAP-SSIAPR 616
+ EL GKTL +LG LGG+ AR P + PR
Sbjct: 142 LLDFPIVELEGKTLGLLGHGELGGAVARLAEAFGMRVLLGQLPGRPARADRLPLGELLPR 201
Query: 617 WSWRTFGLLADYITLHTPLIESTRNFINA 703
D +TLH PL E TR + +
Sbjct: 202 ---------VDALTLHCPLTEDTRGMLGS 221
>UniRef50_Q896Z8 Cluster: 2-hydroxyacid dehydrogenase; n=4;
Clostridium|Rep: 2-hydroxyacid dehydrogenase -
Clostridium tetani
Length = 357
Score = 50.8 bits (116), Expect = 3e-05
Identities = 26/74 (35%), Positives = 45/74 (60%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
D+I++++ K + V N+ G + S ELT L+L L R++VP + ++ G + Y+
Sbjct: 122 DHINMETCRKNNIMVCNSAGYSTSSVVELTFGLILSLLRNIVPLNDEVRNGNTKQG-YSQ 180
Query: 467 SELAGKTLAILGLG 508
+LAGKTL ++G G
Sbjct: 181 YDLAGKTLGVIGAG 194
>UniRef50_Q6A5K9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, putative D-3- phosphoglycerate
dehydrogenase; n=1; Propionibacterium acnes|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase, putative
D-3- phosphoglycerate dehydrogenase - Propionibacterium
acnes
Length = 321
Score = 50.8 bits (116), Expect = 3e-05
Identities = 46/151 (30%), Positives = 68/151 (45%), Gaps = 9/151 (5%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAG---RWDRAL 457
+NID+D+A + GV V + PG + +L TL+L + R A ++AG R+D
Sbjct: 76 NNIDLDAAKQAGVVVTSTPGVLHEATADLAFTLLLEVTRRTGEAERWVRAGRAWRYDHTF 135
Query: 458 YTGSELAGKTLAILGLG--GSA-ARWPLGCXXXXXXXXXXXXXXXXXXAPS-SIAPRWSW 625
G+ L G TL I+GLG G A AR A + + P
Sbjct: 136 MLGAGLQGATLGIVGLGQIGEAMARRGAAFGMNVIYNARHEKDVAAIDAVNLNTQPTRRV 195
Query: 626 RTFGLLA--DYITLHTPLIESTRNFINARCL 712
L A D ++LH PL + TR+ ++A L
Sbjct: 196 ELDELFATSDVVSLHCPLTDETRHLVDADAL 226
>UniRef50_A0HBX6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Comamonas testosteroni
KF-1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Comamonas testosteroni KF-1
Length = 320
Score = 50.8 bits (116), Expect = 3e-05
Identities = 25/74 (33%), Positives = 40/74 (54%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
D++D+++A +GV V A ANA + E LML L R + ++AG W + + G
Sbjct: 86 DSVDMEAARTQGVAVAVAQAANAPAVAEHALALMLALVRQLPQLDQQVRAGGWAGSNWQG 145
Query: 467 SELAGKTLAILGLG 508
+ G T+ I+G G
Sbjct: 146 RDFRGSTVGIVGYG 159
>UniRef50_Q0CUD5 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 743
Score = 50.8 bits (116), Expect = 3e-05
Identities = 26/74 (35%), Positives = 40/74 (54%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
+ ID D+ K+G+ ++N PGANA EL TL L +AR + +T + + G
Sbjct: 509 EKIDQDACVKRGIKILNTPGANARDVAELVVTLALSVARGIRSITTRQMSKPVPKETCNG 568
Query: 467 SELAGKTLAILGLG 508
L KT+ I+G+G
Sbjct: 569 LTLYQKTIGIIGMG 582
>UniRef50_A2QX18 Cluster: Contig An11c0250, complete genome; n=3;
Trichocomaceae|Rep: Contig An11c0250, complete genome -
Aspergillus niger
Length = 336
Score = 50.8 bits (116), Expect = 3e-05
Identities = 27/74 (36%), Positives = 42/74 (56%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
D ID ++ K+G+ V NAP + +L L+L R++ PA +L AG + + + G
Sbjct: 91 DPIDTEACAKRGIIVTNAPDPVTDATADLAVLLLLGALRNLNPAIRSLYAGTFKQGVGFG 150
Query: 467 SELAGKTLAILGLG 508
+ GKTL ILG+G
Sbjct: 151 HDPQGKTLGILGMG 164
>UniRef50_Q9HK29 Cluster: 2-hydroxyacid dehydrogenase related
protein; n=4; Thermoplasmatales|Rep: 2-hydroxyacid
dehydrogenase related protein - Thermoplasma acidophilum
Length = 309
Score = 50.8 bits (116), Expect = 3e-05
Identities = 26/74 (35%), Positives = 43/74 (58%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DN+D+++ K G+ V N P A+A S E +++L L + +++GRW R +
Sbjct: 73 DNVDMNAMKKNGIMVSNIPTASADSVAEHALSMVLSLIKDQRFLDAEIRSGRWPR-ITRS 131
Query: 467 SELAGKTLAILGLG 508
S+L GKT I+G+G
Sbjct: 132 SDLMGKTFGIVGMG 145
>UniRef50_Q6F7L0 Cluster: Glycerate dehydrogenase; n=3;
Gammaproteobacteria|Rep: Glycerate dehydrogenase -
Acinetobacter sp. (strain ADP1)
Length = 318
Score = 50.4 bits (115), Expect = 4e-05
Identities = 30/80 (37%), Positives = 43/80 (53%), Gaps = 6/80 (7%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL--- 457
+N+D+ +A +G+ V N G S + T TLML LA ++ A+ GRW +A
Sbjct: 78 NNVDLRAAKAQGIVVCNCQGYGTASVAQHTLTLMLALATSLLRYDHAVAQGRWQQASQFC 137
Query: 458 ---YTGSELAGKTLAILGLG 508
Y EL+GKTL I+G G
Sbjct: 138 FLDYPIIELSGKTLGIVGYG 157
>UniRef50_Q3KAR6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=3;
Gammaproteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Pseudomonas fluorescens
(strain PfO-1)
Length = 322
Score = 50.4 bits (115), Expect = 4e-05
Identities = 25/74 (33%), Positives = 39/74 (52%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
+ +D+ +A +G+ V N G NA S + ++L L R + A++ G W + +
Sbjct: 79 EQVDLQAASDRGLTVTNGAGVNASSVADHAMAMLLALVRDIPRCDGAVRRGEWPKIM--R 136
Query: 467 SELAGKTLAILGLG 508
LAGK L ILGLG
Sbjct: 137 PSLAGKRLGILGLG 150
>UniRef50_Q0RXU8 Cluster: Phosphoglycerate dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: Phosphoglycerate dehydrogenase
- Rhodococcus sp. (strain RHA1)
Length = 325
Score = 50.4 bits (115), Expect = 4e-05
Identities = 29/76 (38%), Positives = 37/76 (48%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNIDV A + GV V+ GANA+S E T + L R V + G W+R G
Sbjct: 83 DNIDVKCANEAGVVVVAPLGANAISVAEHTIGMALAAVRRTVELDADCRRGGWERT--PG 140
Query: 467 SELAGKTLAILGLGGS 514
EL G +LG G +
Sbjct: 141 RELHGGVWGLLGAGAT 156
>UniRef50_A1W7V5 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Proteobacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Acidovorax sp. (strain JS42)
Length = 337
Score = 50.4 bits (115), Expect = 4e-05
Identities = 25/74 (33%), Positives = 38/74 (51%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
D+ID+D G+ V N P + E L+L ++RH+V + + G + + G
Sbjct: 76 DHIDLDYCRAHGIAVSNVPDYGDATVAEHAFALLLAVSRHIVTGAERTRRGDFSQHGLRG 135
Query: 467 SELAGKTLAILGLG 508
EL GKTL +LG G
Sbjct: 136 FELRGKTLGVLGTG 149
>UniRef50_A4RX85 Cluster: Predicted protein; n=3; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 454
Score = 50.4 bits (115), Expect = 4e-05
Identities = 48/163 (29%), Positives = 70/163 (42%), Gaps = 21/163 (12%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELT-CTLMLVLA------RHVVPASTALKAGRW 445
+NI V + G+ V N PGANA + EL C+L+L +HV + G +
Sbjct: 93 NNIPVKEMSELGIPVFNTPGANANAVKELVVCSLLLASRGIIEGNKHVNDVINVEENGDY 152
Query: 446 ---------DRALYTGSELAGKTLAILGLGGSAARW---PLGCXXXXXXXXXXXXXXXXX 589
D+A++ G+E+ GKTL ++GLG +R LG
Sbjct: 153 AKISVRIEKDKAMFGGTEIEGKTLGVIGLGAIGSRVVNAALGLGMNVIGYDPVLSLEAAW 212
Query: 590 XAPSSIAPRWS-WRTFGLLADYITLHTPLIES-TRNFINARCL 712
P R LADYIT+H P I+ T + I+A+ L
Sbjct: 213 RLPGDKMSRADDLDELFALADYITIHVPYIKGVTHHLIDAKSL 255
>UniRef50_Q27SN5 Cluster: Beta xylosidase-like protein; n=1;
Acanthamoeba castellanii|Rep: Beta xylosidase-like
protein - Acanthamoeba castellanii (Amoeba)
Length = 222
Score = 50.4 bits (115), Expect = 4e-05
Identities = 35/142 (24%), Positives = 59/142 (41%), Gaps = 5/142 (3%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR----- 451
D +DV +A ++ + V N PGA + ++ L+L R A L+ G W+R
Sbjct: 56 DTVDVKAATERNIWVCNTPGAVTNATADVALYLLLAACRRATEAERFLRDGSWERQGSDI 115
Query: 452 ALYTGSELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRT 631
+ G+ GKTL I+G+G + A S
Sbjct: 116 LAFWGNNPEGKTLGIIGMGNIGKALAKRAAALDMRVIYYKRTPLPKEEENG-ATYKSMDD 174
Query: 632 FGLLADYITLHTPLIESTRNFI 697
+D+I++HTPL ++TR+ +
Sbjct: 175 LLAESDFISIHTPLTDATRHIL 196
>UniRef50_Q81N95 Cluster: D-3-phosphoglycerate dehydrogenase,
putative; n=19; Bacteria|Rep: D-3-phosphoglycerate
dehydrogenase, putative - Bacillus anthracis
Length = 390
Score = 50.0 bits (114), Expect = 6e-05
Identities = 39/149 (26%), Positives = 62/149 (41%), Gaps = 12/149 (8%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD------ 448
+NI V+ +KG+ V N PGANA + EL +++ +R+++ + K +
Sbjct: 62 NNIPVERCTEKGIVVFNTPGANANAVKELIIASLIMSSRNIINGVSWTKNLEGEEVPQLV 121
Query: 449 ---RALYTGSELAGKTLAILGLGGSAA---RWPLGCXXXXXXXXXXXXXXXXXXAPSSIA 610
+ + GSE+AGK L ++GLG A L + +
Sbjct: 122 ESGKKQFVGSEIAGKRLGVIGLGAIGALVANDALALGMDVVGYDPYISVETAWRLSTHVQ 181
Query: 611 PRWSWRTFGLLADYITLHTPLIESTRNFI 697
+S DYITLH PL T+ I
Sbjct: 182 RAFSLDEIFATCDYITLHIPLTNQTKGMI 210
>UniRef50_A4FIJ9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
D-3-phosphoglycerate dehydrogenase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 322
Score = 50.0 bits (114), Expect = 6e-05
Identities = 26/74 (35%), Positives = 38/74 (51%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
D +D +A ++G+ V N PG NA + + T ML L RH ++ G W G
Sbjct: 85 DGVDHVAAAERGIPVANLPGFNADAVADWTVGAMLHLLRHYAAGHRKVEQGGWGPEGLRG 144
Query: 467 SELAGKTLAILGLG 508
+L+ T+AILG G
Sbjct: 145 RDLSALTVAILGFG 158
>UniRef50_A0Q8P3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=3; Francisella tularensis subsp.
novicida|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase - Francisella tularensis subsp. novicida
(strain U112)
Length = 327
Score = 50.0 bits (114), Expect = 6e-05
Identities = 36/142 (25%), Positives = 56/142 (39%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
+N+D+D A K + V P + S E T L+L L R + A +K ++ G
Sbjct: 78 NNVDIDHAKKLDIKVARVPAYSPFSVAEHTLALLLCLNRKIHKAYNRVKESNFNIEGLEG 137
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
++ KT+ I+G G + C APS + A
Sbjct: 138 FDVHRKTIGIIGFGNIGKAFAQICSGFGGEILVYDPYADRAIAPSYVTFVDDKNKLFAEA 197
Query: 647 DYITLHTPLIESTRNFINARCL 712
D I+LH PL T+ I+ + L
Sbjct: 198 DIISLHCPLNADTKYIIDEKAL 219
>UniRef50_Q5KQ73 Cluster: D-3-phosphoglycerate dehydrogenase,
putative; n=3; Filobasidiella neoformans|Rep:
D-3-phosphoglycerate dehydrogenase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 594
Score = 50.0 bits (114), Expect = 6e-05
Identities = 29/76 (38%), Positives = 40/76 (52%), Gaps = 2/76 (2%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL--Y 460
D ID+ +A K G+ V+N PG NA + EL +ML LAR ++ G L +
Sbjct: 110 DKIDIVNAKKLGIPVMNTPGVNAQAVAELAFGMMLSLARQTPSIDRKIRKGASVTKLDGW 169
Query: 461 TGSELAGKTLAILGLG 508
G L GKTL ++G G
Sbjct: 170 KGQMLYGKTLGVIGGG 185
>UniRef50_Q1MQK2 Cluster: Phosphoglycerate dehydrogenase and related
dehydrogenases; n=1; Lawsonia intracellularis
PHE/MN1-00|Rep: Phosphoglycerate dehydrogenase and
related dehydrogenases - Lawsonia intracellularis
(strain PHE/MN1-00)
Length = 302
Score = 49.6 bits (113), Expect = 7e-05
Identities = 26/74 (35%), Positives = 42/74 (56%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNIDV+ A +K + + N P A++ E T L+L L R + +++G W + + G
Sbjct: 81 DNIDVEYAQEKNIIIYNPPKGYAIAVAEFTVGLILSLIRQIPYQDKEVRSGVWHKRI--G 138
Query: 467 SELAGKTLAILGLG 508
+ L GK + I+GLG
Sbjct: 139 NLLHGKRVGIIGLG 152
>UniRef50_Q0C254 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=2;
Alphaproteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Hyphomonas neptunium
(strain ATCC 15444)
Length = 337
Score = 49.6 bits (113), Expect = 7e-05
Identities = 35/139 (25%), Positives = 58/139 (41%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
+ +DV++A G V A G N S + +M+ + R A +A+KAG+W+ + G
Sbjct: 88 EKVDVEAARDLGRVVAIAAGGNDASVADQVIGMMISIGRRFQEAQSAMKAGKWN--ILVG 145
Query: 467 SELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLA 646
+EL + + I+G G + ++ T A
Sbjct: 146 TELYRRKVGIVGFGRIGRSLARRLSGFEAEILVCAPRLASEDIETFGLRHVAFETLLKEA 205
Query: 647 DYITLHTPLIESTRNFINA 703
DYI++H PL TR+ NA
Sbjct: 206 DYISVHAPLTPETRHMFNA 224
>UniRef50_A1HMI9 Cluster: Phosphoglycerate dehydrogenase; n=1;
Thermosinus carboxydivorans Nor1|Rep: Phosphoglycerate
dehydrogenase - Thermosinus carboxydivorans Nor1
Length = 326
Score = 49.6 bits (113), Expect = 7e-05
Identities = 29/76 (38%), Positives = 39/76 (51%), Gaps = 2/76 (2%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNID+ +A G+ V N PG NA S ELT +++ L R + K G W +
Sbjct: 78 DNIDLAAAKTLGIPVANTPGGNATSVAELTLGMIINLYRKINILDRETKKGNWMSWEFRP 137
Query: 467 S--ELAGKTLAILGLG 508
S E+ GKT I+G G
Sbjct: 138 SSYEVKGKTHGIIGFG 153
>UniRef50_Q4IXK9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic domain:D- isomer specific
2-hydroxyacid dehydrogenase, NAD binding domain; n=1;
Azotobacter vinelandii AvOP|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic domain:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD binding domain
- Azotobacter vinelandii AvOP
Length = 388
Score = 49.2 bits (112), Expect = 1e-04
Identities = 27/73 (36%), Positives = 41/73 (56%)
Frame = +2
Query: 290 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGS 469
++D+D+ ++GV V G+ ++ EL TL+L R ++PA A + GRW + G
Sbjct: 147 HLDLDACTRRGVAVAEGRGS-PIAPAELAWTLILNARRRLLPAIAAFREGRWQTNI--GE 203
Query: 470 ELAGKTLAILGLG 508
LAG TL I G G
Sbjct: 204 RLAGLTLGIWGYG 216
>UniRef50_Q44NM9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=1;
Chlorobium limicola DSM 245|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Chlorobium limicola DSM 245
Length = 305
Score = 49.2 bits (112), Expect = 1e-04
Identities = 26/74 (35%), Positives = 40/74 (54%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
D++D+D A +KG+ V N P S ELT + L L R V A +K G W + + G
Sbjct: 82 DSVDLDYAKQKGIVVTNTPDGPTRSVAELTIAMTLALLRKVPQAHMNIKQGVWKKEI--G 139
Query: 467 SELAGKTLAILGLG 508
+ + K + ++GLG
Sbjct: 140 NLMYEKKVGLIGLG 153
>UniRef50_A1HQU2 Cluster: Glyoxylate reductase; n=1; Thermosinus
carboxydivorans Nor1|Rep: Glyoxylate reductase -
Thermosinus carboxydivorans Nor1
Length = 324
Score = 49.2 bits (112), Expect = 1e-04
Identities = 25/76 (32%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW--DRALY 460
DN+D+ + ++G+ N PG + +LT L+L AR + + +GRW + +
Sbjct: 80 DNVDIAACTRRGIPFGNTPGVLVEATADLTFGLLLCAARRIHEGWNQVASGRWLNNHDVP 139
Query: 461 TGSELAGKTLAILGLG 508
G +L GKTL I+G+G
Sbjct: 140 FGIDLYGKTLGIVGMG 155
>UniRef50_A1G3C5 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Salinispora arenicola
CNS205|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Salinispora arenicola
CNS205
Length = 345
Score = 49.2 bits (112), Expect = 1e-04
Identities = 26/75 (34%), Positives = 38/75 (50%), Gaps = 1/75 (1%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DNID+ +A + GV V N PG E L++++ R + + G W++ L T
Sbjct: 77 DNIDIPAASRAGVVVANNPGLGGKPVSEHALGLLIMITRDLTAVARDAMTGAWEKRLTTR 136
Query: 467 S-ELAGKTLAILGLG 508
EL G TL I+G G
Sbjct: 137 RVELTGGTLGIVGCG 151
Score = 33.9 bits (74), Expect = 4.0
Identities = 17/38 (44%), Positives = 25/38 (65%), Gaps = 1/38 (2%)
Frame = +1
Query: 511 VGREVATRMYA-FGMNIIGFDPFVSADQCAQFHCTKME 621
VG +A R A F M ++ +DP+VSA+Q AQ TK++
Sbjct: 153 VGGWMARRASAGFQMRVLAYDPYVSAEQMAQVGATKVD 190
>UniRef50_A0ZEB8 Cluster: Predicted dehydrogenase; n=6;
Cyanobacteria|Rep: Predicted dehydrogenase - Nodularia
spumigena CCY 9414
Length = 341
Score = 49.2 bits (112), Expect = 1e-04
Identities = 31/80 (38%), Positives = 44/80 (55%), Gaps = 3/80 (3%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW-DRALYT 463
D ID+ A K GV V+N PG + + E T ++L LA+ + + +K G + R
Sbjct: 90 DAIDISVATKHGVVVVNNPGLSTTAVAEHTICMILALAKKLTFLNQCVKTGNYLIRNQVQ 149
Query: 464 GSELAGKTLAILGLG--GSA 517
+L GKTL I+GLG GSA
Sbjct: 150 PMQLEGKTLGIVGLGRIGSA 169
>UniRef50_A0QQ27 Cluster: Glyoxylate reductase; n=4;
Mycobacterium|Rep: Glyoxylate reductase - Mycobacterium
smegmatis (strain ATCC 700084 / mc(2)155)
Length = 322
Score = 49.2 bits (112), Expect = 1e-04
Identities = 45/148 (30%), Positives = 65/148 (43%), Gaps = 6/148 (4%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR-W--DRAL 457
+ IDV++A + G+ V N PGANA S E T LML R + A +AGR W D L
Sbjct: 83 NTIDVETATQLGILVANMPGANAPSVAEGTVLLMLAALRRLPQLDRATRAGRGWPTDPTL 142
Query: 458 -YTGSELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTF 634
T ++ G T+ ++G G A R + PRW
Sbjct: 143 GDTVRDIGGCTVGLVGYGNVAKR------VERIVLAMGAEQVLHTSTRDTGHPRWR-NLP 195
Query: 635 GLLA--DYITLHTPLIESTRNFINARCL 712
LLA D ++LH PL +++R + +
Sbjct: 196 DLLAASDIVSLHLPLTDTSRGLLGPEAI 223
>UniRef50_Q9TXJ5 Cluster: D-3-phosphoglycerate dehydrogenase-like
protein; n=10; cellular organisms|Rep:
D-3-phosphoglycerate dehydrogenase-like protein -
Leishmania major
Length = 511
Score = 49.2 bits (112), Expect = 1e-04
Identities = 25/74 (33%), Positives = 40/74 (54%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
+ +D+D A +GV V N+P AN S EL ++ L+R + S + G W++
Sbjct: 188 NQVDLDYATTRGVAVFNSPFANTRSVAELVIGEIISLSRKMTQRSEEVHRGVWNKTHVGC 247
Query: 467 SELAGKTLAILGLG 508
E+ GKT+ I+G G
Sbjct: 248 YEVRGKTVGIVGYG 261
Score = 34.7 bits (76), Expect = 2.3
Identities = 22/61 (36%), Positives = 34/61 (55%), Gaps = 1/61 (1%)
Frame = +3
Query: 75 LIVDGVGAKCAELLNAYG-IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 251
L+++GV ELL + G I + ++ LL +I + L +RS TQVT+ +LDA
Sbjct: 116 LLLEGVNPIAKELLESKGCIVEYIPNALPRDTLLEKIRDVHFLGIRSKTQVTQAILDAAP 175
Query: 252 K 254
K
Sbjct: 176 K 176
>UniRef50_A3H6F3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Caldivirga
maquilingensis IC-167|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Caldivirga
maquilingensis IC-167
Length = 326
Score = 49.2 bits (112), Expect = 1e-04
Identities = 27/80 (33%), Positives = 45/80 (56%), Gaps = 2/80 (2%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL--Y 460
D+ID+D+A ++G+ V P + +L L++ LAR V+ +++G + +
Sbjct: 84 DHIDLDAATRRGIPVGYTPEVLVEAVADLAIGLIITLARRVIEGDRLVRSGEAYKVWGEF 143
Query: 461 TGSELAGKTLAILGLGGSAA 520
G+E+ GKTL ILGLG A
Sbjct: 144 LGTEVWGKTLGILGLGNIGA 163
>UniRef50_Q89QF5 Cluster: Blr3173 protein; n=3; Bradyrhizobium|Rep:
Blr3173 protein - Bradyrhizobium japonicum
Length = 360
Score = 48.8 bits (111), Expect = 1e-04
Identities = 27/80 (33%), Positives = 43/80 (53%), Gaps = 1/80 (1%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR-WDRALYT 463
D +DV++ GV V+N G NA S E +ML L++ ++ + L+ R +R
Sbjct: 101 DPVDVEACTDAGVLVVNQSGGNAHSVAEHALAMMLTLSKRIIQSDRRLRRERDVNRNDLV 160
Query: 464 GSELAGKTLAILGLGGSAAR 523
G+E+ KT+ I+GLG R
Sbjct: 161 GNEVEHKTVGIIGLGNVGRR 180
>UniRef50_Q2LUG0 Cluster: 2-hydroxyacid dehydrogenase, D-isomer
specific; n=1; Syntrophus aciditrophicus SB|Rep:
2-hydroxyacid dehydrogenase, D-isomer specific -
Syntrophus aciditrophicus (strain SB)
Length = 326
Score = 48.8 bits (111), Expect = 1e-04
Identities = 38/146 (26%), Positives = 62/146 (42%), Gaps = 8/146 (5%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD---RAL 457
+++ + S +G+ ++N G + +L TL+L L R V +++G W L
Sbjct: 93 NHLPITSCQSRGIRIVNTQGVLTDATADLALTLLLSLTRRVREGEALVRSGHWKGWAPDL 152
Query: 458 YTGSELAGKTLAILG---LGGSAAR--WPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWS 622
G+ L GKT ILG +G + AR W +G IA R
Sbjct: 153 LLGTGLTGKTCGILGSGPIGRAFARRVWAIGMKVIFWNREGNQKPVDFGV---DIAARLP 209
Query: 623 WRTFGLLADYITLHTPLIESTRNFIN 700
+D ++LH PL ++TR +N
Sbjct: 210 LDELLRQSDVLSLHCPLTDTTRGLLN 235
>UniRef50_Q1GJ08 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=24; Rhodobacterales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Silicibacter sp. (strain TM1040)
Length = 322
Score = 48.8 bits (111), Expect = 1e-04
Identities = 26/77 (33%), Positives = 41/77 (53%), Gaps = 3/77 (3%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD---RAL 457
++ID ++A GV V N PGA + ++ TLML+ AR +++G+W
Sbjct: 85 NHIDAEAARAAGVEVTNTPGAVTDATADIALTLMLMTARRAGEGERLVRSGQWQGWHPTQ 144
Query: 458 YTGSELAGKTLAILGLG 508
G L+GK L ++GLG
Sbjct: 145 MLGLHLSGKRLGVVGLG 161
>UniRef50_Q125T3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Polaromonas sp.
JS666|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Polaromonas sp. (strain
JS666 / ATCC BAA-500)
Length = 309
Score = 48.8 bits (111), Expect = 1e-04
Identities = 28/75 (37%), Positives = 40/75 (53%), Gaps = 1/75 (1%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW-DRALYT 463
D I V A +G+ V + PG + CEL L+L L R + + ++ GRW D A
Sbjct: 73 DGIPVAYAQARGIAVTHTPGVLDDAVCELGVGLLLGLLRDIPASDRFVRDGRWSDSAYPL 132
Query: 464 GSELAGKTLAILGLG 508
+ LAGK + I+GLG
Sbjct: 133 TTSLAGKAVGIVGLG 147
>UniRef50_Q03U10 Cluster: 2-hydroxyacid dehydrogenase; n=1;
Lactobacillus brevis ATCC 367|Rep: 2-hydroxyacid
dehydrogenase - Lactobacillus brevis (strain ATCC 367 /
JCM 1170)
Length = 330
Score = 48.8 bits (111), Expect = 1e-04
Identities = 29/81 (35%), Positives = 43/81 (53%), Gaps = 2/81 (2%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPG-ANALSACELTCTLMLVLARHVVPASTALKAGRW-DRALY 460
+N+DV +A G V P S E +L + R VPA+ +AGR+ DRA +
Sbjct: 85 NNVDVKAAKAHGTLVTIVPQLVERDSVAENELVNLLTMVRRTVPAAERERAGRYEDRAEF 144
Query: 461 TGSELAGKTLAILGLGGSAAR 523
G+EL+GKT ++G G +R
Sbjct: 145 MGNELSGKTFGVIGCGNIGSR 165
>UniRef50_A1HM37 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=3; cellular organisms|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Thermosinus carboxydivorans Nor1
Length = 365
Score = 48.8 bits (111), Expect = 1e-04
Identities = 38/145 (26%), Positives = 59/145 (40%), Gaps = 5/145 (3%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
+N++V A K+G+ V N G NA + + T LML R++ A ++K G W +
Sbjct: 107 ENVNVKEATKRGILVFNIEGRNAEAVSDFTVGLMLAECRNIARAHYSIKNGGWRKEFSNS 166
Query: 467 S---ELAGKTLAILGLG--GSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRT 631
EL GK + ++G G G L I T
Sbjct: 167 DWVPELKGKKVGLVGFGYIGRLVAQKLSGFGVTRLVYDPFVDEETIRGAGCIPV--DKET 224
Query: 632 FGLLADYITLHTPLIESTRNFINAR 706
+D+I+LH L EST+N + +
Sbjct: 225 LFKESDFISLHARLSESTKNLVGEK 249
>UniRef50_A0FZA8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=3; Burkholderia|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Burkholderia phymatum STM815
Length = 321
Score = 48.8 bits (111), Expect = 1e-04
Identities = 37/142 (26%), Positives = 58/142 (40%), Gaps = 4/142 (2%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYT- 463
D DVD K+G+ + N P S + +L+L+ AR + + +KAG+W + +
Sbjct: 74 DAFDVDYLNKRGILLTNTPDVLTESTADTAFSLILLTARRLAELAAFVKAGKWTKKIAED 133
Query: 464 --GSELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSI-APRWSWRTF 634
G ++ KTL I+GLG A A R S+
Sbjct: 134 RFGVDVHHKTLGIVGLGRIGTSVARRAALGFQMNVLYVDQGVNEKAEREYGAKRVSFDEL 193
Query: 635 GLLADYITLHTPLIESTRNFIN 700
+D++ L PL TRN I+
Sbjct: 194 LKTSDFVLLQAPLTPETRNLIS 215
>UniRef50_A7EUN0 Cluster: Formate dehydrogenase; n=2;
Sclerotiniaceae|Rep: Formate dehydrogenase - Sclerotinia
sclerotiorum 1980
Length = 436
Score = 48.8 bits (111), Expect = 1e-04
Identities = 27/78 (34%), Positives = 43/78 (55%), Gaps = 4/78 (5%)
Frame = +2
Query: 287 DNIDVDSAGKK--GVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY 460
D++D+++A K G+ V G+N +S E +LVL R+ VPA ++AG WD A
Sbjct: 159 DHVDLNAANKTNGGITVAEVTGSNVVSVAEHVVMTILVLVRNFVPAHEQIQAGEWDVAAA 218
Query: 461 TGSE--LAGKTLAILGLG 508
+E L GK + + +G
Sbjct: 219 AKNEFDLEGKVVGTVAVG 236
>UniRef50_Q8F5N8 Cluster: Phosphoglycerate dehydrogenase; n=4;
Leptospira|Rep: Phosphoglycerate dehydrogenase -
Leptospira interrogans
Length = 332
Score = 48.4 bits (110), Expect = 2e-04
Identities = 25/74 (33%), Positives = 39/74 (52%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
D++ ++ ++G+ V P A ++ ELT LM+ R V A LK G W R +TG
Sbjct: 83 DSVPLNLCKERGIAVAYTPDAVTMAVAELTIGLMISSTRKVFLAHQELKTGGWSR--FTG 140
Query: 467 SELAGKTLAILGLG 508
L T+ I+G+G
Sbjct: 141 KRLGESTIGIVGVG 154
>UniRef50_Q6A895 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Actinomycetales|Rep: D-3-phosphoglycerate dehydrogenase
- Propionibacterium acnes
Length = 417
Score = 48.4 bits (110), Expect = 2e-04
Identities = 23/74 (31%), Positives = 39/74 (52%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
+ +D+D+ + GV NAP +N S EL ++ LAR + +T + G W ++
Sbjct: 98 NQMDLDALAEAGVPAFNAPYSNTRSVVELVMAEIIALARRLGDRNTQMHNGVWRKSAIGS 157
Query: 467 SELAGKTLAILGLG 508
E+ G+ L I+G G
Sbjct: 158 HEIRGRRLGIIGYG 171
>UniRef50_Q67M76 Cluster: Phosphoglycerate dehydrogenase, N-terminal
domain; n=1; Symbiobacterium thermophilum|Rep:
Phosphoglycerate dehydrogenase, N-terminal domain -
Symbiobacterium thermophilum
Length = 140
Score = 48.4 bits (110), Expect = 2e-04
Identities = 23/53 (43%), Positives = 33/53 (62%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW 445
DNIDV +A ++G+ V+N P ANA+S E + LA+ VV A++ GRW
Sbjct: 77 DNIDVAAATERGILVLNTPEANAVSVAEHAIAAIAALAKRVVFMDRAVRDGRW 129
>UniRef50_Q3A6W9 Cluster: 3-phosphoglycerate dehydrogenase; n=1;
Pelobacter carbinolicus DSM 2380|Rep: 3-phosphoglycerate
dehydrogenase - Pelobacter carbinolicus (strain DSM 2380
/ Gra Bd 1)
Length = 321
Score = 48.4 bits (110), Expect = 2e-04
Identities = 24/74 (32%), Positives = 37/74 (50%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DN+D+D + ++ P A + EL +ML L+R ++ A L+ G W + G
Sbjct: 74 DNVDLDYLRNHDLKLVRIPQPGARAVAELAFGMMLALSRQILVADQLLRKGTWAKHQLRG 133
Query: 467 SELAGKTLAILGLG 508
L K L I+GLG
Sbjct: 134 HLLVNKQLGIVGLG 147
>UniRef50_Q11JF3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Mesorhizobium sp.
BNC1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Mesorhizobium sp. (strain BNC1)
Length = 312
Score = 48.4 bits (110), Expect = 2e-04
Identities = 24/74 (32%), Positives = 40/74 (54%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
+ ID+++ +K + V N G NA S E L+L + R + A A+++G W+ A Y
Sbjct: 78 EKIDMEAVREKKIIVANNAGTNAFSVAEQALGLLLAVLRDIPAAERAVRSGIWEEARYPR 137
Query: 467 SELAGKTLAILGLG 508
+ K + I+GLG
Sbjct: 138 PLIFEKRVGIVGLG 151
>UniRef50_A1UEI9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=5; Mycobacterium|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Mycobacterium sp. (strain KMS)
Length = 321
Score = 48.4 bits (110), Expect = 2e-04
Identities = 31/78 (39%), Positives = 41/78 (52%), Gaps = 4/78 (5%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRAL 457
DNIDV +A GV V N PG + + T L+L + R VV L++ R W +
Sbjct: 83 DNIDVAAAHAAGVTVTNTPGVLDNATADHTFALILAVTRRVVDGDRFLRSRRPWIWGPRM 142
Query: 458 YTGSEL-AGKTLAILGLG 508
TG ++ AG TL ILG G
Sbjct: 143 LTGLDVSAGATLGILGYG 160
>UniRef50_A2A023 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Flexibacteraceae|Rep: D-3-phosphoglycerate dehydrogenase
- Microscilla marina ATCC 23134
Length = 316
Score = 48.0 bits (109), Expect = 2e-04
Identities = 25/74 (33%), Positives = 38/74 (51%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
D ID+ +A +G+ V+NAP N + E T ++L L +V A +K W R G
Sbjct: 77 DKIDLSAANARGIKVLNAPEGNRDAVGEQTIGMLLSLLHNVQRADWEVKNFAWKREANRG 136
Query: 467 SELAGKTLAILGLG 508
EL K + ++G G
Sbjct: 137 VELMDKVVGVIGYG 150
>UniRef50_UPI000023EBBC Cluster: hypothetical protein FG00146.1; n=1;
Gibberella zeae PH-1|Rep: hypothetical protein FG00146.1
- Gibberella zeae PH-1
Length = 1068
Score = 47.6 bits (108), Expect = 3e-04
Identities = 41/145 (28%), Positives = 58/145 (40%), Gaps = 6/145 (4%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHV--VPASTALKAGRWDRALY 460
D IDV++ + V V N PG NA + E+T L L +AR V V ++ +
Sbjct: 824 DKIDVEACKRHNVKVCNTPGVNASAVAEMTLCLALTVAREVPDVVIRQKIQGEAIRKETV 883
Query: 461 TGSELAGKTLAILGLGG-SAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFG 637
G L+ K + ++G+G A + P P T
Sbjct: 884 AGMLLSRKIIGVVGMGHIGQAIAQMFVGGLQAEIIAFDPYFHDNQGPWDTIPYKRVETLT 943
Query: 638 LL---ADYITLHTPLIESTRNFINA 703
L AD +TLH PL ST+N I A
Sbjct: 944 ELLEVADVVTLHVPLTHSTKNMIAA 968
>UniRef50_Q6FCL4 Cluster: 2-keto-D-gluconate reductase; n=15;
Pseudomonadales|Rep: 2-keto-D-gluconate reductase -
Acinetobacter sp. (strain ADP1)
Length = 321
Score = 47.6 bits (108), Expect = 3e-04
Identities = 28/81 (34%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR---AL 457
DN DV +K + + + P + +L TL++ AR V KAG W R A
Sbjct: 78 DNYDVQYLNQKKIWLAHTPHVLTETTADLAFTLLVSAARKVPQLDAWTKAGEWKRTVGAA 137
Query: 458 YTGSELAGKTLAILGLGGSAA 520
G ++ GKTL I+GLG A
Sbjct: 138 QFGQDIFGKTLGIIGLGNIGA 158
>UniRef50_A0GDF1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Burkholderia
phytofirmans PsJN|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Burkholderia phytofirmans
PsJN
Length = 274
Score = 47.6 bits (108), Expect = 3e-04
Identities = 26/85 (30%), Positives = 45/85 (52%), Gaps = 6/85 (7%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA---- 454
+++D ++ K+G+G++ PG + +S E LML L R+++P + AG W +
Sbjct: 40 NHLDTETCRKRGIGIVACPGYSTISVPEHAFALMLALRRNLMPYWHDVYAGGWSGSPTFY 99
Query: 455 --LYTGSELAGKTLAILGLGGSAAR 523
L+ +L G TL I+G G R
Sbjct: 100 AELHPIQDLHGSTLGIVGAGHGGKR 124
>UniRef50_Q5KFZ5 Cluster: Phosphoglycerate dehydrogenase, putative;
n=2; Filobasidiella neoformans|Rep: Phosphoglycerate
dehydrogenase, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 339
Score = 47.6 bits (108), Expect = 3e-04
Identities = 25/78 (32%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAG-RWDRALYT 463
DN+ + + +G+ V N PG+NA + EL LML + R VV ++ G R
Sbjct: 90 DNVPLPTCLSRGIAVTNIPGSNAFAVAELAIALMLTVLRRVVEVDKRIRGGERVPSIEAL 149
Query: 464 GSELAGKTLAILGLGGSA 517
L GK + ++G+G A
Sbjct: 150 APGLGGKKVGLVGMGDIA 167
>UniRef50_UPI000023F60F Cluster: hypothetical protein FG08018.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG08018.1 - Gibberella zeae PH-1
Length = 901
Score = 47.2 bits (107), Expect = 4e-04
Identities = 40/140 (28%), Positives = 55/140 (39%), Gaps = 3/140 (2%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAG-RWDRALYT 463
D IDVD+ +G+ + N PG NA + EL TL AR V +G + +
Sbjct: 90 DKIDVDACASRGIKIFNTPGVNARAVAELVLTLATASARQVGSIIAKQSSGILVPKEKCS 149
Query: 464 GSELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLL 643
G L KT+ ILG+G A I + + +L
Sbjct: 150 GLILHEKTIGILGMGNIGKCVAKIFRGAFDANVIAYDPFLPADAWEEIPHKRATSVEEVL 209
Query: 644 --ADYITLHTPLIESTRNFI 697
+D IT+H PL TRN I
Sbjct: 210 RSSDVITVHMPLTPETRNLI 229
>UniRef50_Q5KYJ7 Cluster: Dehydrogenase; n=3; Firmicutes|Rep:
Dehydrogenase - Geobacillus kaustophilus
Length = 334
Score = 47.2 bits (107), Expect = 4e-04
Identities = 39/147 (26%), Positives = 67/147 (45%), Gaps = 9/147 (6%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD----RA 454
+ +DVD+A +KG+ V N + + L+L LAR +V + +K+G W+ +
Sbjct: 80 NTVDVDAATEKGIIVANVTDYSIDEVSDHALALLLSLARKIVKLNHEVKSGTWNFNVGKP 139
Query: 455 LYTGSELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTF 634
+Y L G+TL ++GLG R P P+ +A + +
Sbjct: 140 IY---RLRGRTLGLVGLG----RIP-QALAKKAQAFGLRVIAYDPYVPAKVADELNVQLL 191
Query: 635 GL-----LADYITLHTPLIESTRNFIN 700
GL +DYI++H PL + T+ I+
Sbjct: 192 GLNDVFRQSDYISVHAPLTKETKGMIS 218
Score = 32.7 bits (71), Expect = 9.2
Identities = 13/46 (28%), Positives = 26/46 (56%)
Frame = +1
Query: 508 RVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPSS 645
R+ + +A + AFG+ +I +DP+V A + + + L D++ S
Sbjct: 155 RIPQALAKKAQAFGLRVIAYDPYVPAKVADELNVQLLGLNDVFRQS 200
>UniRef50_Q5FKH9 Cluster: Glyoxylate reductase; n=1; Lactobacillus
acidophilus|Rep: Glyoxylate reductase - Lactobacillus
acidophilus
Length = 321
Score = 47.2 bits (107), Expect = 4e-04
Identities = 28/77 (36%), Positives = 41/77 (53%), Gaps = 3/77 (3%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW---DRAL 457
D+ID+D A +KG+ V N P + EL T+++ AR + AL+ G + D
Sbjct: 81 DHIDIDYAREKGIVVTNCPNSVLRPTAELALTMIMASARRIRYYDHALREGVFLNVDEYD 140
Query: 458 YTGSELAGKTLAILGLG 508
G + GKTL ILG+G
Sbjct: 141 SQGYTIEGKTLGILGMG 157
>UniRef50_A4A9T4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=1; Congregibacter
litoralis KT71|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Congregibacter litoralis
KT71
Length = 316
Score = 47.2 bits (107), Expect = 4e-04
Identities = 40/145 (27%), Positives = 63/145 (43%), Gaps = 3/145 (2%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW-DRALYT 463
DN+D+ +A ++G+ V N P +A +LT L+L R V AL+ G W A
Sbjct: 77 DNVDLVAAKERGILVSNTPVVTEDTA-DLTFALLLATCRRVGECERALRGGDWAGGAALM 135
Query: 464 GSELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLL 643
G + G L I+G G+ + A +S RW LL
Sbjct: 136 GRRVHGAKLGIIGF-GAIGQAVAQRARGFDMDVGYHGPRRKADAEASTGARWYESLDQLL 194
Query: 644 --ADYITLHTPLIESTRNFINARCL 712
+D ++L+ PL ++TR+ +N L
Sbjct: 195 EESDIVSLNCPLTQATRHIMNETSL 219
>UniRef50_A3RV54 Cluster: 2-hydroxyacid dehydrogenase; n=5;
Burkholderiales|Rep: 2-hydroxyacid dehydrogenase -
Ralstonia solanacearum UW551
Length = 331
Score = 47.2 bits (107), Expect = 4e-04
Identities = 25/78 (32%), Positives = 40/78 (51%), Gaps = 4/78 (5%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR-ALYT 463
+N+DV + +GV V N P + + LML AR + + ++ G W + +Y
Sbjct: 79 NNVDVAACTARGVVVTNTPDVLTQTTADFGFALMLATARRITESERFVRRGEWQKTGIYN 138
Query: 464 ---GSELAGKTLAILGLG 508
GS++ G TL ILG+G
Sbjct: 139 QMLGSDIYGATLGILGMG 156
>UniRef50_Q0CK41 Cluster: Putative uncharacterized protein; n=5;
Trichocomaceae|Rep: Putative uncharacterized protein -
Aspergillus terreus (strain NIH 2624)
Length = 519
Score = 47.2 bits (107), Expect = 4e-04
Identities = 27/56 (48%), Positives = 33/56 (58%)
Frame = +2
Query: 341 PGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLG 508
PG N S + T L+L LARHV A+K G W +L G LAGKTL ++GLG
Sbjct: 110 PGVN--STVQHTWALILALARHVARDDAAVKRGGWQGSL--GMSLAGKTLGLVGLG 161
>UniRef50_Q7WNI7 Cluster: Putative dehydrogenase; n=1; Bordetella
bronchiseptica|Rep: Putative dehydrogenase - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 333
Score = 46.8 bits (106), Expect = 5e-04
Identities = 38/149 (25%), Positives = 63/149 (42%), Gaps = 7/149 (4%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
D IDVD+A + G+ + G+NA EL L+L + R + + ++AG+W +A
Sbjct: 83 DRIDVDAARRLGIPLAITAGSNAGPVAELAVALILGVYRRLCYVNREMRAGQWPKAEMRE 142
Query: 467 S--ELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGL 640
S ++ KT+ ++G G + AP+ + R L
Sbjct: 143 SCFQIHRKTIGLVGFGNIGRKL---ARRLSGFEPDAILYCDQQAAPAEVERALGARRVEL 199
Query: 641 -----LADYITLHTPLIESTRNFINARCL 712
+D ++LH P STR I+A L
Sbjct: 200 PELLAASDIVSLHLPCTASTRRLIDAAAL 228
>UniRef50_Q5LT44 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=16; Proteobacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Silicibacter pomeroyi
Length = 330
Score = 46.8 bits (106), Expect = 5e-04
Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 3/76 (3%)
Frame = +2
Query: 290 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD--RALY- 460
+ID D+ G+ V N P + ++ TLML++AR L+AG+W R +
Sbjct: 89 HIDSDAVRAHGITVSNTPDVLSECTADIAMTLMLMVARRAGEGERELRAGQWTGWRPTHL 148
Query: 461 TGSELAGKTLAILGLG 508
GS+++GK L I+G G
Sbjct: 149 VGSKVSGKVLGIVGFG 164
>UniRef50_Q2S4S4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Salinibacter ruber DSM 13855|Rep: D-3-phosphoglycerate
dehydrogenase - Salinibacter ruber (strain DSM 13855)
Length = 512
Score = 46.8 bits (106), Expect = 5e-04
Identities = 25/74 (33%), Positives = 39/74 (52%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
D +D + +GV V+N P +N S E+ M+VLAR + A+ + W +
Sbjct: 159 DTVDKQACADEGVLVLNDPVSNGRSVVEMVMGEMVVLARRLYTANETGRRHLWTKDSTRR 218
Query: 467 SELAGKTLAILGLG 508
EL KTL+++GLG
Sbjct: 219 YELMDKTLSVIGLG 232
>UniRef50_Q2NVC4 Cluster: Putative 2-hydroxyacid-family
dehydrogenase; n=1; Sodalis glossinidius str.
'morsitans'|Rep: Putative 2-hydroxyacid-family
dehydrogenase - Sodalis glossinidius (strain morsitans)
Length = 211
Score = 46.8 bits (106), Expect = 5e-04
Identities = 29/73 (39%), Positives = 43/73 (58%), Gaps = 1/73 (1%)
Frame = +2
Query: 293 IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALK-AGRWDRALYTGS 469
ID+D+A + ++ ++A ELT L+L LARH+VP + AL+ + W + L G
Sbjct: 86 IDLDAARAHNI-IVCGTASDAAPPMELTWALILGLARHLVPENQALRHSDPWQQIL--GM 142
Query: 470 ELAGKTLAILGLG 508
L GK L +LGLG
Sbjct: 143 TLKGKLLCLLGLG 155
>UniRef50_A4SWE6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 326
Score = 46.8 bits (106), Expect = 5e-04
Identities = 32/143 (22%), Positives = 58/143 (40%), Gaps = 3/143 (2%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRAL 457
+N ++D+A K+GV + N PG + L+L A+ + + ++ G+ W
Sbjct: 81 NNFNLDAATKRGVIMTNTPGVLDKATATHAWALLLATAKRISESERYVREGKWKGWSPMT 140
Query: 458 YTGSELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFG 637
+ G ++ GKTL I GLG + A T
Sbjct: 141 FIGQDVDGKTLGIAGLGRIGTMFARKAAAFDMKVIYTNEQRNFDFEKDHGATFVDKETLL 200
Query: 638 LLADYITLHTPLIESTRNFINAR 706
+D++++H PL T+ +I A+
Sbjct: 201 KESDFLSIHLPLTPETKYYIGAK 223
>UniRef50_Q3S8E5 Cluster: Putative D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=1; Paracoccus
pantotrophus|Rep: Putative D-isomer specific
2-hydroxyacid dehydrogenase family protein - Paracoccus
pantotrophus (Thiosphaera pantotropha)
Length = 338
Score = 46.4 bits (105), Expect = 7e-04
Identities = 38/138 (27%), Positives = 56/138 (40%)
Frame = +2
Query: 290 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGS 469
+ID+ + + G+ V A A + ELT LM+ L R + +L+AG W + G
Sbjct: 83 SIDLAACDRLGITVC-ATDALHQTTVELTVWLMIALMRGLPRECASLRAGGWQVGV--GR 139
Query: 470 ELAGKTLAILGLGGSAARWPLGCXXXXXXXXXXXXXXXXXXAPSSIAPRWSWRTFGLLAD 649
L GKTL ++GLG C A S AD
Sbjct: 140 SLGGKTLGVVGLGNMGIPVAKICKIMGMDVIAWSPNLTQERAAEHGVRAVSKEELFAQAD 199
Query: 650 YITLHTPLIESTRNFINA 703
+TLH P I +T + ++A
Sbjct: 200 VVTLHMPHINATEHLVSA 217
>UniRef50_Q11JH0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Mesorhizobium sp.
BNC1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Mesorhizobium sp. (strain BNC1)
Length = 342
Score = 46.4 bits (105), Expect = 7e-04
Identities = 28/79 (35%), Positives = 44/79 (55%), Gaps = 5/79 (6%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
D ID++ A ++GV V G+NA + E T L+L R + A +++ G+W +YT
Sbjct: 84 DKIDLEGAERQGVYVAITAGSNAGAVAEHTIMLILAALRRLALADQSMREGKW---IYTE 140
Query: 467 -----SELAGKTLAILGLG 508
+L+GKT+ ILG G
Sbjct: 141 LRPLCRKLSGKTVGILGFG 159
>UniRef50_A7CR80 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Opitutaceae bacterium
TAV2|Rep: D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Opitutaceae bacterium TAV2
Length = 355
Score = 46.4 bits (105), Expect = 7e-04
Identities = 23/74 (31%), Positives = 37/74 (50%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
DN+D + + G+ + N PG ++ ++ LAR +KAG W ++ G
Sbjct: 125 DNVDFAACQRLGLPISNTPGMFGREVADVAVGYVIALARQTFAIDRTVKAGGWIKS--AG 182
Query: 467 SELAGKTLAILGLG 508
LAGKT+A+ G G
Sbjct: 183 ISLAGKTVALAGFG 196
>UniRef50_A4R4W0 Cluster: Formate dehydrogenase; n=1; Magnaporthe
grisea|Rep: Formate dehydrogenase - Magnaporthe grisea
(Rice blast fungus) (Pyricularia grisea)
Length = 364
Score = 46.4 bits (105), Expect = 7e-04
Identities = 28/84 (33%), Positives = 44/84 (52%), Gaps = 4/84 (4%)
Frame = +2
Query: 287 DNIDVDSAGKK--GVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY 460
D++D+++A K G+ V G+N +S E +LVL R+ VPA ++ G WD A
Sbjct: 167 DHVDLNAANKTNGGITVAEVTGSNVVSVAEHVLMTILVLVRNFVPALEMIQTGEWDVAGA 226
Query: 461 TGSE--LAGKTLAILGLGGSAARW 526
+E L GK + + + GS W
Sbjct: 227 AKNEYDLEGKVVGTVAV-GSIGSW 249
>UniRef50_Q12VM6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; cellular organisms|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Methanococcoides burtonii (strain DSM
6242)
Length = 317
Score = 46.4 bits (105), Expect = 7e-04
Identities = 24/74 (32%), Positives = 39/74 (52%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
D ++ + K G+ V P A ++ EL ++L L+R + ++ G WDR Y G
Sbjct: 81 DGVNFELCNKYGIKVTYTPDAPTMAVAELCVGIILDLSRKISYTDRNVRKGVWDR--YMG 138
Query: 467 SELAGKTLAILGLG 508
+ L GKT+ I G+G
Sbjct: 139 NLLYGKTVGIFGMG 152
>UniRef50_Q9K7P7 Cluster: Glycerate dehydrogenase; n=8;
Bacillaceae|Rep: Glycerate dehydrogenase - Bacillus
halodurans
Length = 324
Score = 46.0 bits (104), Expect = 0.001
Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 3/77 (3%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR---AL 457
DNID+ A K+GV V + PG + +LT L++ R + + ++ +W +
Sbjct: 78 DNIDIKEATKRGVSVGHTPGVLTEATADLTFALLMATGRRLRESIDYVRNDQWKSWGPFM 137
Query: 458 YTGSELAGKTLAILGLG 508
TG + G TL I+G+G
Sbjct: 138 LTGQAIYGTTLGIIGMG 154
>UniRef50_A5N5A9 Cluster: SerA; n=1; Clostridium kluyveri DSM
555|Rep: SerA - Clostridium kluyveri DSM 555
Length = 320
Score = 46.0 bits (104), Expect = 0.001
Identities = 23/74 (31%), Positives = 39/74 (52%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
+N+D+ +A + + + NAP +N + E T L++ LA+ L+ G + G
Sbjct: 76 NNVDIKTASELSIQITNAPESNKNTVAEYTMGLIIALAKKFFLYDRGLRKGNFKVRDILG 135
Query: 467 SELAGKTLAILGLG 508
+L GK L I+GLG
Sbjct: 136 IDLEGKVLGIVGLG 149
>UniRef50_A4EAR0 Cluster: Putative uncharacterized protein; n=1;
Collinsella aerofaciens ATCC 25986|Rep: Putative
uncharacterized protein - Collinsella aerofaciens ATCC
25986
Length = 387
Score = 46.0 bits (104), Expect = 0.001
Identities = 28/94 (29%), Positives = 48/94 (51%), Gaps = 10/94 (10%)
Frame = +2
Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD------ 448
+NI V+ KKGV V N+PGAN+ + EL ++++ +R VV + ++ D
Sbjct: 61 NNIPVEEYAKKGVVVFNSPGANSNAVKELVLGMLVLSSRGVVQSMNWVRDNADDPEIQVD 120
Query: 449 ----RALYTGSELAGKTLAILGLGGSAARWPLGC 538
+ + G EL GK + ++GLG ++ C
Sbjct: 121 AEKAKKAFVGRELKGKRIGVIGLGNVGSKVANAC 154
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 740,048,477
Number of Sequences: 1657284
Number of extensions: 15907799
Number of successful extensions: 76838
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 66198
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 76150
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 57024798702
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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