Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= NV021801
(669 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000DB72A4 Cluster: PREDICTED: similar to 3-phosphog... 107 2e-22
UniRef50_UPI00015B605A Cluster: PREDICTED: similar to GA19489-PA... 100 3e-20
UniRef50_O43175 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 93 6e-18
UniRef50_Q3AQU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 92 1e-17
UniRef50_A1SM51 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 92 1e-17
UniRef50_A7SFV8 Cluster: Predicted protein; n=1; Nematostella ve... 91 2e-17
UniRef50_Q58424 Cluster: D-3-phosphoglycerate dehydrogenase; n=7... 91 2e-17
UniRef50_Q3ZX05 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 89 1e-16
UniRef50_A0LMX1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 87 3e-16
UniRef50_Q1IVI0 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 87 5e-16
UniRef50_Q0W4A2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 87 5e-16
UniRef50_Q9X1C1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 86 6e-16
UniRef50_P35136 Cluster: D-3-phosphoglycerate dehydrogenase; n=8... 86 6e-16
UniRef50_A6C9V4 Cluster: Phosphoglycerate dehydrogenase; n=1; Pl... 86 8e-16
UniRef50_A7HDB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 85 1e-15
UniRef50_A6UQN3 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 85 1e-15
UniRef50_A0L7J1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 85 2e-15
UniRef50_Q897N8 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 84 3e-15
UniRef50_A5UQ03 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 84 3e-15
UniRef50_A2U4T1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 84 3e-15
UniRef50_A1DFM4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 84 3e-15
UniRef50_Q2AHU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 83 4e-15
UniRef50_Q8PW48 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 83 4e-15
UniRef50_O29445 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 83 6e-15
UniRef50_Q1AXS3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 83 8e-15
UniRef50_Q8TYK0 Cluster: Predicted dehydrogenase related to phos... 83 8e-15
UniRef50_Q67TJ9 Cluster: Phosphoglycerate dehydrogenase; n=1; Sy... 82 1e-14
UniRef50_Q8UJZ6 Cluster: Phosphoglycerate dehydrogenase; n=3; Al... 81 2e-14
UniRef50_Q1PZY1 Cluster: Similar to D-3-phosphoglycerate dehydro... 81 2e-14
UniRef50_O04130 Cluster: D-3-phosphoglycerate dehydrogenase, chl... 81 3e-14
UniRef50_Q7UQL2 Cluster: Phosphoglycerate dehydrogenase; n=2; Pl... 79 1e-13
UniRef50_P73821 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 79 1e-13
UniRef50_A3EWA5 Cluster: Phosphoglycerate dehydrogenase; n=2; Ba... 78 2e-13
UniRef50_Q8EN61 Cluster: Phosphoglycerate dehydrogenase; n=2; Ba... 78 2e-13
UniRef50_Q1NQ97 Cluster: D-isomer specific 2-hydroxyacid dehydro... 78 2e-13
UniRef50_A7CYD6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 77 4e-13
UniRef50_A7P9P5 Cluster: Chromosome chr3 scaffold_8, whole genom... 77 4e-13
UniRef50_O67741 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 76 7e-13
UniRef50_O33116 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 76 7e-13
UniRef50_A6PUG1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 76 9e-13
UniRef50_Q4L766 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 75 1e-12
UniRef50_Q8ZTC7 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 75 1e-12
UniRef50_Q8YIU3 Cluster: D-3-PHOSPHOGLYCERATE DEHYDROGENASE; n=7... 75 2e-12
UniRef50_A4FIF2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 75 2e-12
UniRef50_Q8R716 Cluster: Phosphoglycerate dehydrogenase and rela... 74 3e-12
UniRef50_A6C2G1 Cluster: Phosphoglycerate dehydrogenase; n=1; Pl... 74 3e-12
UniRef50_A4MA79 Cluster: D-isomer specific 2-hydroxyacid dehydro... 74 4e-12
UniRef50_Q97N23 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 73 5e-12
UniRef50_Q7D366 Cluster: AGR_pAT_578p; n=2; Agrobacterium tumefa... 73 8e-12
UniRef50_Q0EUV6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 8e-12
UniRef50_Q2LGV1 Cluster: Phosphoglycerate dehydrogenase; n=6; Ha... 73 8e-12
UniRef50_A0V9Y4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 71 2e-11
UniRef50_UPI0000DC0E13 Cluster: 3-phosphoglycerate dehydrogenase... 70 4e-11
UniRef50_Q8EMJ8 Cluster: Hypothetical conserved protein; n=1; Oc... 70 4e-11
UniRef50_A1IDH6 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 70 6e-11
UniRef50_Q8XPB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 69 1e-10
UniRef50_A4YUP8 Cluster: Putative D-3-phosphoglycerate dehydroge... 69 1e-10
UniRef50_Q9RUU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 69 1e-10
UniRef50_UPI00015BAF48 Cluster: D-isomer specific 2-hydroxyacid ... 68 2e-10
UniRef50_Q4WHR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 68 2e-10
UniRef50_A4FHH0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 67 3e-10
UniRef50_Q0J5C2 Cluster: Os08g0447000 protein; n=11; Viridiplant... 67 3e-10
UniRef50_A7HEG1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 67 4e-10
UniRef50_UPI0000E4762C Cluster: PREDICTED: similar to D-3-phosph... 66 5e-10
UniRef50_Q0FX01 Cluster: D-isomer specific 2-hydroxyacid dehydro... 66 5e-10
UniRef50_A1AR04 Cluster: D-isomer specific 2-hydroxyacid dehydro... 66 5e-10
UniRef50_A0JVX0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 66 5e-10
UniRef50_O50096 Cluster: Putative uncharacterized protein PH1388... 66 5e-10
UniRef50_A6ULR7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 66 7e-10
UniRef50_A5URV2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 65 1e-09
UniRef50_Q18XF4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 65 2e-09
UniRef50_A4ETV8 Cluster: Putative uncharacterized protein; n=6; ... 65 2e-09
UniRef50_A6Q7Q2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 64 2e-09
UniRef50_UPI000050F9E4 Cluster: COG0111: Phosphoglycerate dehydr... 64 3e-09
UniRef50_Q6W1I8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 64 4e-09
UniRef50_A6UCB8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 4e-09
UniRef50_A6DQ00 Cluster: SerA; n=1; Lentisphaera araneosa HTCC21... 63 5e-09
UniRef50_A1RDF9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 63 7e-09
UniRef50_A1HSQ7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 63 7e-09
UniRef50_A7NGZ0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 62 9e-09
UniRef50_Q97ZK1 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 62 9e-09
UniRef50_Q6MN05 Cluster: Phosphoglycerate dehydrogenase; n=1; Bd... 61 2e-08
UniRef50_Q39LG4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 61 2e-08
UniRef50_A0UAW1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 61 2e-08
UniRef50_A0RW58 Cluster: Phosphoglycerate dehydrogenase; n=3; Cr... 61 2e-08
UniRef50_Q9WYG2 Cluster: Phosphoglycerate dehydrogenase, putativ... 61 3e-08
UniRef50_Q0ETU3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 61 3e-08
UniRef50_Q5WLJ2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 60 4e-08
UniRef50_Q46VE6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 60 5e-08
UniRef50_A4WXD4 Cluster: Dimethylmenaquinone methyltransferase; ... 60 5e-08
UniRef50_Q88ZU6 Cluster: Phosphoglycerate dehydrogenase; n=2; La... 60 6e-08
UniRef50_Q03WU1 Cluster: Lactate dehydrogenase related dehydroge... 60 6e-08
UniRef50_A3PPC6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 59 8e-08
UniRef50_Q3KBX8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 59 1e-07
UniRef50_A6PPS4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 59 1e-07
UniRef50_Q1K3M3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 58 1e-07
UniRef50_A6EBH4 Cluster: Phosphoglycerate dehydrogenase; n=1; Pe... 58 1e-07
UniRef50_A6CKS4 Cluster: Putative uncharacterized protein; n=1; ... 58 1e-07
UniRef50_Q81T55 Cluster: D-isomer specific 2-hydroxyacid dehydro... 58 2e-07
UniRef50_Q0K073 Cluster: D-3-Phosphoglycerate dehydrogenase; n=2... 58 2e-07
UniRef50_Q031D4 Cluster: Phosphoglycerate dehydrogenase; n=20; S... 58 2e-07
UniRef50_Q7WM64 Cluster: Putative dehydrogenase; n=2; Bordetella... 58 3e-07
UniRef50_Q3Y1E6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 58 3e-07
UniRef50_Q3CIY1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 58 3e-07
UniRef50_Q6L245 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 58 3e-07
UniRef50_Q0FY56 Cluster: Putative phosphoglycerate dehydrogenase... 57 3e-07
UniRef50_Q8EP33 Cluster: Glycerate dehydrogenase; n=2; Bacillace... 57 4e-07
UniRef50_Q21A61 Cluster: D-isomer specific 2-hydroxyacid dehydro... 57 4e-07
UniRef50_P13443 Cluster: Glycerate dehydrogenase; n=15; Viridipl... 56 6e-07
UniRef50_Q3SK87 Cluster: D-isomer specific 2-hydroxyacid dehydro... 56 8e-07
UniRef50_Q4AIL7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 56 8e-07
UniRef50_Q0RXU8 Cluster: Phosphoglycerate dehydrogenase; n=1; Rh... 56 8e-07
UniRef50_A4AN91 Cluster: Predicted dehydrogenase; n=14; Bacteroi... 56 8e-07
UniRef50_Q5KN70 Cluster: D-3-phosphoglycerate dehydrogenase 2, p... 56 8e-07
UniRef50_Q65WI5 Cluster: SerA protein; n=1; Mannheimia succinici... 56 1e-06
UniRef50_Q1LCR9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 56 1e-06
UniRef50_A4YFM2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 56 1e-06
UniRef50_O86322 Cluster: POSSIBLE D-3-PHOSPHOGLYCERATE DEHYDROGE... 55 1e-06
UniRef50_A6G5P3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 55 1e-06
UniRef50_Q8FPW0 Cluster: Putative uncharacterized protein; n=1; ... 55 2e-06
UniRef50_Q67M76 Cluster: Phosphoglycerate dehydrogenase, N-termi... 55 2e-06
UniRef50_Q1FF19 Cluster: D-isomer specific 2-hydroxyacid dehydro... 55 2e-06
UniRef50_Q5KE95 Cluster: Phosphoglycerate dehydrogenase; n=2; Fi... 55 2e-06
UniRef50_Q825H6 Cluster: Putative glycerate dehydrogenase; n=1; ... 54 2e-06
UniRef50_Q49ZM5 Cluster: Putative dehydrogenase; n=1; Staphyloco... 54 2e-06
UniRef50_Q01W77 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 2e-06
UniRef50_A7HBU0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 2e-06
UniRef50_A0HBX6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 2e-06
UniRef50_A7EUN0 Cluster: Formate dehydrogenase; n=2; Sclerotinia... 54 2e-06
UniRef50_Q88YI0 Cluster: Phosphoglycerate dehydrogenase; n=5; Ba... 54 3e-06
UniRef50_Q83AZ4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 3e-06
UniRef50_Q30V14 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 3e-06
UniRef50_A7HM61 Cluster: Glyoxylate reductase; n=1; Fervidobacte... 54 3e-06
UniRef50_A2A023 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 54 3e-06
UniRef50_Q8Y3L1 Cluster: Lmo2824 protein; n=14; Bacillales|Rep: ... 54 4e-06
UniRef50_A0VQR0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 4e-06
UniRef50_Q5KQ73 Cluster: D-3-phosphoglycerate dehydrogenase, put... 54 4e-06
UniRef50_Q8CPW2 Cluster: Glycerate dehydrogenase; n=4; Staphyloc... 53 5e-06
UniRef50_Q82U25 Cluster: D-isomer specific 2-hydroxyacid dehydro... 53 5e-06
UniRef50_Q1WVK4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 53 5e-06
UniRef50_Q03YV3 Cluster: Lactate dehydrogenase related enzyme; n... 53 5e-06
UniRef50_Q82XE1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 53 7e-06
UniRef50_Q6AMI7 Cluster: Related to D-3-phosphoglycerate dehydro... 53 7e-06
UniRef50_Q3A6W9 Cluster: 3-phosphoglycerate dehydrogenase; n=1; ... 53 7e-06
UniRef50_Q4IV69 Cluster: D-isomer specific 2-hydroxyacid dehydro... 53 7e-06
UniRef50_A6LZ51 Cluster: D-isomer specific 2-hydroxyacid dehydro... 53 7e-06
UniRef50_A1G3C5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 53 7e-06
UniRef50_A7P8C8 Cluster: Chromosome chr3 scaffold_8, whole genom... 53 7e-06
UniRef50_Q6MY49 Cluster: NAD-dependant D-isomer specific 2-hydro... 53 7e-06
UniRef50_A4R4W0 Cluster: Formate dehydrogenase; n=1; Magnaporthe... 53 7e-06
UniRef50_O58320 Cluster: Glyoxylate reductase; n=16; cellular or... 53 7e-06
UniRef50_A7CY19 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 1e-05
UniRef50_A6T665 Cluster: Putative D-3-phosphoglycerate dehydroge... 52 1e-05
UniRef50_A1JTE6 Cluster: Putative oxidoreductase; n=1; Yersinia ... 52 1e-05
UniRef50_A0QQ27 Cluster: Glyoxylate reductase; n=4; Mycobacteriu... 52 1e-05
UniRef50_Q0PQJ5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 1e-05
UniRef50_A3ZW64 Cluster: Phosphoglycerate dehydrogenase, putativ... 52 1e-05
UniRef50_A1HMI9 Cluster: Phosphoglycerate dehydrogenase; n=1; Th... 52 1e-05
UniRef50_Q0CUD5 Cluster: Putative uncharacterized protein; n=1; ... 52 1e-05
UniRef50_A2QX18 Cluster: Contig An11c0250, complete genome; n=3;... 52 1e-05
UniRef50_O28495 Cluster: 2-hydroxyacid dehydrogenase, putative; ... 52 1e-05
UniRef50_Q0W672 Cluster: Glycerate dehydrogenase; n=2; Archaea|R... 52 1e-05
UniRef50_P40054 Cluster: D-3-phosphoglycerate dehydrogenase 1; n... 52 1e-05
UniRef50_P0A9T3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 52 1e-05
UniRef50_Q8R8Q2 Cluster: Lactate dehydrogenase and related dehyd... 52 2e-05
UniRef50_Q81N95 Cluster: D-3-phosphoglycerate dehydrogenase, put... 52 2e-05
UniRef50_Q5FUD9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 52 2e-05
UniRef50_Q3KAR6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 2e-05
UniRef50_Q44NM9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 2e-05
UniRef50_A3K878 Cluster: 2-hydroxyacid dehydrogenase; n=1; Sagit... 52 2e-05
UniRef50_A2F8V0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 2e-05
UniRef50_Q7UQC8 Cluster: Probable 2-hydroxyacid dehydrogenase; n... 51 2e-05
UniRef50_Q5FUW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 51 2e-05
UniRef50_A1W9A3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 51 2e-05
UniRef50_A4EAR0 Cluster: Putative uncharacterized protein; n=1; ... 51 3e-05
UniRef50_A0RUD3 Cluster: 2 lactate dehydrogenase; n=2; Thermopro... 51 3e-05
UniRef50_Q8F5N8 Cluster: Phosphoglycerate dehydrogenase; n=4; Le... 50 4e-05
UniRef50_Q896Z8 Cluster: 2-hydroxyacid dehydrogenase; n=4; Clost... 50 4e-05
UniRef50_Q72KT6 Cluster: Glycerate dehydrogenase/glyoxylate redu... 50 4e-05
UniRef50_Q2S4U0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 50 4e-05
UniRef50_Q11UL6 Cluster: Phosphoglycerate dehydrogenase; n=1; Cy... 50 4e-05
UniRef50_A7IJ69 Cluster: D-isomer specific 2-hydroxyacid dehydro... 50 4e-05
UniRef50_A0LN07 Cluster: D-isomer specific 2-hydroxyacid dehydro... 50 4e-05
UniRef50_A4S3N1 Cluster: Predicted protein; n=2; Ostreococcus|Re... 50 4e-05
UniRef50_Q5KFZ5 Cluster: Phosphoglycerate dehydrogenase, putativ... 50 4e-05
UniRef50_Q7WEA3 Cluster: Phosphoglycerate dehydrogenase; n=1; Bo... 50 5e-05
UniRef50_Q74CK1 Cluster: Glycerate dehydrogenase; n=12; Bacteria... 50 5e-05
UniRef50_A5V6T9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 50 5e-05
UniRef50_A1AQ02 Cluster: D-isomer specific 2-hydroxyacid dehydro... 50 5e-05
UniRef50_Q9HK29 Cluster: 2-hydroxyacid dehydrogenase related pro... 50 5e-05
UniRef50_Q89QF5 Cluster: Blr3173 protein; n=3; Bradyrhizobium|Re... 50 7e-05
UniRef50_Q89J71 Cluster: 2-hydroxyacid dehydrogenase; n=8; Brady... 50 7e-05
UniRef50_Q6A5K9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 50 7e-05
UniRef50_O34815 Cluster: YoaD; n=2; Bacillus|Rep: YoaD - Bacillu... 50 7e-05
UniRef50_Q27SN5 Cluster: Beta xylosidase-like protein; n=1; Acan... 50 7e-05
UniRef50_UPI00015BD3AA Cluster: UPI00015BD3AA related cluster; n... 49 9e-05
UniRef50_Q1GJ08 Cluster: D-isomer specific 2-hydroxyacid dehydro... 49 9e-05
UniRef50_A6CRV0 Cluster: 2-hydroxyacid dehydrogenase; n=15; Baci... 49 9e-05
UniRef50_A3UGW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 49 9e-05
UniRef50_Q6F7L0 Cluster: Glycerate dehydrogenase; n=3; Gammaprot... 49 1e-04
UniRef50_Q63VJ5 Cluster: D-3-phosphoglycerate dehydrogenase; n=8... 49 1e-04
UniRef50_Q7X388 Cluster: Phosphoglycerate dehydrogenase; n=3; Es... 49 1e-04
UniRef50_Q03U10 Cluster: 2-hydroxyacid dehydrogenase; n=1; Lacto... 49 1e-04
UniRef50_A7CR80 Cluster: D-isomer specific 2-hydroxyacid dehydro... 49 1e-04
UniRef50_A5Z3X2 Cluster: Putative uncharacterized protein; n=1; ... 49 1e-04
UniRef50_A5N5A9 Cluster: SerA; n=1; Clostridium kluyveri DSM 555... 49 1e-04
UniRef50_A0ZEB8 Cluster: Predicted dehydrogenase; n=6; Cyanobact... 49 1e-04
UniRef50_Q125T3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 48 2e-04
UniRef50_A1HQU2 Cluster: Glyoxylate reductase; n=1; Thermosinus ... 48 2e-04
UniRef50_A0GDF1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 48 2e-04
UniRef50_Q27SS3 Cluster: Glycerate dehydrogenase-like protein; n... 48 2e-04
UniRef50_Q5V1E2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 48 2e-04
UniRef50_Q11JF3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 48 2e-04
UniRef50_A1W7V5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 48 2e-04
UniRef50_A0JWH0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 48 2e-04
UniRef50_UPI0000DA2A77 Cluster: PREDICTED: similar to D-3-phosph... 48 3e-04
UniRef50_UPI0000D9FBAD Cluster: PREDICTED: similar to 3-phosphog... 48 3e-04
UniRef50_UPI000023F60F Cluster: hypothetical protein FG08018.1; ... 48 3e-04
UniRef50_A4FK85 Cluster: D-3-phosphoglycerate dehydrogenase, put... 48 3e-04
UniRef50_A4RX85 Cluster: Predicted protein; n=3; Ostreococcus|Re... 48 3e-04
UniRef50_Q4WMF4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 48 3e-04
UniRef50_Q8TR50 Cluster: Glycerate dehydrogenase; n=2; Methanosa... 48 3e-04
UniRef50_Q986P2 Cluster: Phosphoglycerate dehydrogenase; n=14; c... 47 4e-04
UniRef50_Q11JH0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 47 4e-04
UniRef50_A4FIJ9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 47 4e-04
UniRef50_A4ARG6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 47 4e-04
UniRef50_A1HM37 Cluster: D-isomer specific 2-hydroxyacid dehydro... 47 4e-04
UniRef50_Q9TXJ5 Cluster: D-3-phosphoglycerate dehydrogenase-like... 47 4e-04
UniRef50_Q6CDS0 Cluster: Similar to tr|O94020 Candida albicans Y... 47 4e-04
UniRef50_A2SRM1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 47 4e-04
UniRef50_Q7NEV2 Cluster: Phosphoglycerate dehydrogenase; n=6; Ba... 47 5e-04
UniRef50_Q5FKH9 Cluster: Glyoxylate reductase; n=1; Lactobacillu... 47 5e-04
UniRef50_A6C853 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 47 5e-04
UniRef50_A3RV54 Cluster: 2-hydroxyacid dehydrogenase; n=5; Burkh... 47 5e-04
UniRef50_A1GFX2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 47 5e-04
UniRef50_Q89LI6 Cluster: Blr4558 protein; n=6; Bradyrhizobiaceae... 46 6e-04
UniRef50_Q6A895 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 46 6e-04
UniRef50_Q5LT44 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 6e-04
UniRef50_Q1MQK2 Cluster: Phosphoglycerate dehydrogenase and rela... 46 6e-04
UniRef50_Q1M6M5 Cluster: Putative glyoxylate reductase; n=1; Rhi... 46 6e-04
UniRef50_Q120S8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 6e-04
UniRef50_A6GGA6 Cluster: Probable 2-hydroxyacid dehydrogenase; n... 46 6e-04
UniRef50_Q7WNI7 Cluster: Putative dehydrogenase; n=1; Bordetella... 46 8e-04
UniRef50_Q1CG62 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 8e-04
UniRef50_A7HWK6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 8e-04
UniRef50_A1UEI9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 8e-04
UniRef50_Q752A0 Cluster: AFR675Wp; n=3; Saccharomycetales|Rep: A... 46 8e-04
UniRef50_Q5KYJ7 Cluster: Dehydrogenase; n=3; Firmicutes|Rep: Deh... 46 0.001
UniRef50_Q4PK14 Cluster: Predicted D-isomer specific 2-hydroxyac... 46 0.001
UniRef50_Q4IXK9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 0.001
UniRef50_Q214B1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 0.001
UniRef50_A1RC54 Cluster: Glyoxylate reductase; n=2; Actinomyceta... 46 0.001
UniRef50_A0Z6W9 Cluster: Spermidine/putrescine ABC transporter A... 46 0.001
UniRef50_A4R1I1 Cluster: Putative uncharacterized protein; n=1; ... 46 0.001
UniRef50_A3H6F3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 0.001
UniRef50_Q0C254 Cluster: D-isomer specific 2-hydroxyacid dehydro... 45 0.001
UniRef50_Q9HVG5 Cluster: Glycerate dehydrogenase; n=23; Gammapro... 45 0.002
UniRef50_Q8YEC6 Cluster: Gluconate 2-dehydrogenase; n=72; Alphap... 45 0.002
UniRef50_Q1MPI0 Cluster: Lactate dehydrogenase and related dehyd... 45 0.002
UniRef50_Q0RXQ1 Cluster: Probable phosphoglycerate dehydrogenase... 45 0.002
UniRef50_UPI000023EBBC Cluster: hypothetical protein FG00146.1; ... 44 0.003
UniRef50_Q126V3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.003
UniRef50_O94574 Cluster: Putative 2-hydroxyacid dehydrogenase C1... 44 0.003
UniRef50_UPI0000383A41 Cluster: COG1052: Lactate dehydrogenase a... 44 0.003
UniRef50_Q6FCL4 Cluster: 2-keto-D-gluconate reductase; n=15; Pse... 44 0.003
UniRef50_Q64UR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 44 0.003
UniRef50_Q04DF1 Cluster: Lactate dehydrogenase related enzyme; n... 44 0.003
UniRef50_A4EQ78 Cluster: Dehydrogenase; n=1; Roseobacter sp. SK2... 44 0.003
UniRef50_A3IA61 Cluster: D-3 phosphoglycerate dehydrogenase; n=1... 44 0.003
UniRef50_A0Y9Y1 Cluster: Glyoxylate reductase; n=2; unclassified... 44 0.003
UniRef50_A0FZA8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.003
UniRef50_Q7X9L3 Cluster: Formate dehydrogenase; n=4; Magnoliophy... 44 0.003
UniRef50_Q98GE4 Cluster: Phosphoglycerate dehydrogenase; n=5; Rh... 44 0.004
UniRef50_Q931A1 Cluster: Putative; n=2; Rhizobiales|Rep: Putativ... 44 0.004
UniRef50_Q5ZYW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 44 0.004
UniRef50_Q1R7K3 Cluster: 2-hydroxyacid dehydrogenase; n=7; Enter... 44 0.004
UniRef50_Q12CS0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.004
UniRef50_Q0B1Q1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.004
UniRef50_A3JX80 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.004
UniRef50_Q2UDC2 Cluster: Glyoxylate/hydroxypyruvate reductase; n... 44 0.004
UniRef50_A1S0J0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.004
UniRef50_Q9K7P7 Cluster: Glycerate dehydrogenase; n=8; Bacillace... 43 0.006
UniRef50_Q49UN3 Cluster: NAD-dependent formate dehydrogenase; n=... 43 0.006
UniRef50_Q2S4S4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 43 0.006
UniRef50_Q2LUG0 Cluster: 2-hydroxyacid dehydrogenase, D-isomer s... 43 0.006
UniRef50_Q0FF66 Cluster: Glycolate reductase; n=2; Alphaproteoba... 43 0.006
UniRef50_UPI00015B49ED Cluster: PREDICTED: similar to putative g... 43 0.008
UniRef50_Q2KZD5 Cluster: Putative reductase precursor; n=1; Bord... 43 0.008
UniRef50_A5G1C9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 43 0.008
UniRef50_Q9KEA4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 42 0.010
UniRef50_Q397E0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.010
UniRef50_P73990 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.010
UniRef50_Q3DL54 Cluster: Glyoxylate reductase, NADH-dependent; n... 42 0.010
UniRef50_Q0LSC3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.010
UniRef50_A4A9T4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.010
UniRef50_A0QVE9 Cluster: Glyoxylate reductase; n=1; Mycobacteriu... 42 0.010
UniRef50_Q5KKI9 Cluster: 2-hydroxyacid dehydrogenase, putative; ... 42 0.010
UniRef50_Q0CK41 Cluster: Putative uncharacterized protein; n=5; ... 42 0.010
UniRef50_Q2NVC4 Cluster: Putative 2-hydroxyacid-family dehydroge... 42 0.013
UniRef50_A6W4F1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.013
UniRef50_A4SWE6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.013
UniRef50_A1BC99 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.013
UniRef50_O75112 Cluster: LIM domain-binding protein 3; n=36; Eut... 42 0.013
UniRef50_Q4FNZ3 Cluster: Probable dehydrogenase; n=2; Candidatus... 42 0.018
UniRef50_Q1GAM7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.018
UniRef50_A7FYM9 Cluster: D-lactate dehydrogenase; n=4; Clostridi... 42 0.018
UniRef50_A6CXX0 Cluster: Dehydrogenase; n=1; Vibrio shilonii AK1... 42 0.018
UniRef50_A4TF35 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.018
UniRef50_A7STU0 Cluster: Predicted protein; n=5; Nematostella ve... 42 0.018
UniRef50_A4QT80 Cluster: Putative uncharacterized protein; n=2; ... 42 0.018
UniRef50_Q97F10 Cluster: Possible phosphoglycerate dehydrogenase... 41 0.024
UniRef50_Q8EMM3 Cluster: Dehydrogenase; n=2; cellular organisms|... 41 0.024
UniRef50_Q8EMJ4 Cluster: 2-ketogluconate reductase; n=1; Oceanob... 41 0.024
UniRef50_Q5LQR6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 41 0.024
UniRef50_A5P5Y8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 41 0.024
UniRef50_A4BPX8 Cluster: Glycerate dehydrogenase; n=1; Nitrococc... 41 0.024
UniRef50_A1SPF8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 41 0.024
UniRef50_A0L0H4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 41 0.024
UniRef50_Q1E5G6 Cluster: Putative uncharacterized protein; n=1; ... 41 0.024
UniRef50_P58220 Cluster: 2-ketogluconate reductase; n=75; Proteo... 41 0.024
UniRef50_Q8U6W5 Cluster: 2-hydroxyacid dehydrogenase; n=3; Alpha... 41 0.031
UniRef50_Q8GC20 Cluster: 3-phosphoglycerate dehydrogenase; n=2; ... 41 0.031
UniRef50_Q126C0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 41 0.031
UniRef50_Q120Q8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 41 0.031
UniRef50_A5G0Z0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 41 0.031
UniRef50_A4SW26 Cluster: D-isomer specific 2-hydroxyacid dehydro... 41 0.031
UniRef50_P17584 Cluster: D-2-hydroxyisocaproate dehydrogenase; n... 41 0.031
UniRef50_Q8G427 Cluster: Possible 2-hydroxyacid dehydrogenase; n... 40 0.041
UniRef50_A1ZGW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 40 0.041
UniRef50_A1WHT1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.041
UniRef50_Q4PP80 Cluster: Putative glyoxylate reductase/hydroxypy... 40 0.041
UniRef50_Q6BTY7 Cluster: Debaryomyces hansenii chromosome C of s... 40 0.041
UniRef50_Q98LH4 Cluster: Phosphoglycerate dehydrogenase; n=3; Me... 40 0.054
UniRef50_Q67M77 Cluster: Phosphoglycerate dehydrogenase, C-termi... 40 0.054
UniRef50_Q39JN8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.054
UniRef50_A6FZB7 Cluster: Putative dehydrogenase; n=1; Plesiocyst... 40 0.054
UniRef50_A5ZA39 Cluster: Putative uncharacterized protein; n=1; ... 40 0.054
UniRef50_A5VE25 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.054
UniRef50_A5N6P2 Cluster: GyaR; n=1; Clostridium kluyveri DSM 555... 40 0.054
UniRef50_A3ZMM2 Cluster: Dehydrogenase; n=1; Blastopirellula mar... 40 0.054
UniRef50_A0Z2L3 Cluster: Putative uncharacterized protein; n=1; ... 40 0.054
UniRef50_A0YEL9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.054
UniRef50_Q9UYH9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.054
UniRef50_A7D498 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.054
UniRef50_Q602T7 Cluster: PKD domain protein; n=1; Methylococcus ... 40 0.072
UniRef50_Q8GQX5 Cluster: 2-oxo-4-phenylbutanoate reductase; n=2;... 40 0.072
UniRef50_Q11QU3 Cluster: D-lactate dehydrogenase; n=1; Cytophaga... 40 0.072
UniRef50_Q11AM6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.072
UniRef50_A5UPU9 Cluster: Glyoxylate reductase; n=12; Bacteria|Re... 40 0.072
UniRef50_A4X4V1 Cluster: Putative uncharacterized protein; n=1; ... 40 0.072
UniRef50_Q8LL97 Cluster: Putative uncharacterized protein; n=1; ... 40 0.072
UniRef50_Q76KF5 Cluster: D-phosphoglycerate dehydrogenase; n=2; ... 40 0.072
UniRef50_Q55F22 Cluster: Putative uncharacterized protein; n=4; ... 40 0.072
UniRef50_A7CUT0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 39 0.095
UniRef50_A5IAP7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 39 0.095
UniRef50_Q9C7T6 Cluster: Phosphoglycerate dehydrogenase, putativ... 39 0.095
UniRef50_Q4PER7 Cluster: Putative uncharacterized protein; n=1; ... 39 0.095
UniRef50_Q8ZXX8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 39 0.095
UniRef50_Q08911 Cluster: Formate dehydrogenase 1; n=71; Eukaryot... 39 0.095
UniRef50_Q89EL0 Cluster: Blr7063 protein; n=1; Bradyrhizobium ja... 39 0.13
UniRef50_Q65DI8 Cluster: Putative uncharacterized protein; n=1; ... 39 0.13
UniRef50_Q5FTU6 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 39 0.13
UniRef50_Q4LAE6 Cluster: Similar to glycerate dehydrogenase; n=1... 39 0.13
UniRef50_Q483F8 Cluster: Putative glyoxylate reductase; n=1; Col... 39 0.13
UniRef50_Q2RTD0 Cluster: Glycolate reductase; n=8; Alphaproteoba... 39 0.13
UniRef50_Q2JEY9 Cluster: Putative uncharacterized protein precur... 39 0.13
UniRef50_A7BQE7 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 39 0.13
UniRef50_A5ZAJ9 Cluster: Putative uncharacterized protein; n=1; ... 39 0.13
UniRef50_A5VEE7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 39 0.13
UniRef50_A1WAF9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 39 0.13
UniRef50_A2QIG5 Cluster: Remark: the blastp hits are due to the ... 39 0.13
UniRef50_A1D255 Cluster: Glycerate dehydrogenase; n=1; Neosartor... 39 0.13
UniRef50_A5YST2 Cluster: Phosphoglycerate dehydrogenase; n=2; Ha... 39 0.13
UniRef50_Q47XK1 Cluster: Erythronate-4-phosphate dehydrogenase; ... 39 0.13
UniRef50_Q5BU19 Cluster: Ribeye a protein; n=4; Clupeocephala|Re... 38 0.17
UniRef50_Q191U4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 38 0.17
UniRef50_Q20595 Cluster: Putative uncharacterized protein; n=3; ... 38 0.17
UniRef50_Q5K657 Cluster: Hydroxyacid dehydrogenase protein Ynl27... 38 0.17
UniRef50_Q4P752 Cluster: Putative uncharacterized protein; n=1; ... 38 0.17
UniRef50_P56545 Cluster: C-terminal-binding protein 2; n=98; Coe... 38 0.17
UniRef50_Q7TVF9 Cluster: HYPOTHETICAL ALANINE AND PROLINE RICH P... 38 0.22
UniRef50_Q5HW94 Cluster: D-isomer specific 2-hydroxyacid dehydro... 38 0.22
UniRef50_Q1V300 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 38 0.22
UniRef50_A3JTB6 Cluster: Putative D-isomer specific 2-hydroxyaci... 38 0.22
UniRef50_A0GVM6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 38 0.22
UniRef50_Q0D7C9 Cluster: Os07g0264100 protein; n=5; Oryza sativa... 38 0.22
UniRef50_Q5KJK5 Cluster: Glycerate-and formate-dehydrogenase, pu... 38 0.22
UniRef50_O69054 Cluster: Phosphonate dehydrogenase; n=16; Bacter... 38 0.22
UniRef50_Q4SJ39 Cluster: Chromosome 21 SCAF14577, whole genome s... 38 0.29
UniRef50_A7J7V2 Cluster: Putative uncharacterized protein N598R;... 38 0.29
UniRef50_Q7W397 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 38 0.29
UniRef50_Q2JE27 Cluster: Putative uncharacterized protein precur... 38 0.29
UniRef50_A1FCW9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 38 0.29
UniRef50_Q1QXV7 Cluster: Erythronate-4-phosphate dehydrogenase; ... 38 0.29
UniRef50_Q98ST8 Cluster: Ff1c; n=6; Clupeocephala|Rep: Ff1c - Da... 37 0.38
UniRef50_Q59141 Cluster: Chitinase precursor; n=1; Aeromonas sp.... 37 0.38
UniRef50_Q13ZE9 Cluster: Putative dehydrogenase, D-3-phosphoglyc... 37 0.38
UniRef50_A6DPW5 Cluster: 2-hydroxyacid-family dehydrogenase; n=2... 37 0.38
UniRef50_A4U8S9 Cluster: Putative ATP-binding protein; n=1; Theo... 37 0.38
UniRef50_A4M784 Cluster: D-isomer specific 2-hydroxyacid dehydro... 37 0.38
UniRef50_Q59516 Cluster: Glycerate dehydrogenase; n=23; Proteoba... 37 0.38
UniRef50_P36234 Cluster: Glycerate dehydrogenase; n=2; Hyphomicr... 37 0.38
UniRef50_UPI000155367B Cluster: PREDICTED: hypothetical protein;... 37 0.51
UniRef50_Q5WAF3 Cluster: 2-ketogluconate reductase; n=1; Bacillu... 37 0.51
UniRef50_Q5NR73 Cluster: 2-hydroxyacid dehydrogenase; n=1; Zymom... 37 0.51
UniRef50_Q1V097 Cluster: Phosphoglycerate dehydrogenase; n=2; Ca... 37 0.51
UniRef50_Q9LH95 Cluster: Arabidopsis thaliana genomic DNA, chrom... 37 0.51
UniRef50_A2ZEL0 Cluster: Putative uncharacterized protein; n=3; ... 37 0.51
UniRef50_A7S382 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 37 0.51
UniRef50_A6QVW0 Cluster: Putative uncharacterized protein; n=1; ... 37 0.51
UniRef50_A7I9X3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 37 0.51
UniRef50_Q4KT76 Cluster: Hoar peptide; n=1; Chrysodeixis chalcit... 36 0.67
UniRef50_Q883D2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 36 0.67
UniRef50_Q398N2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 36 0.67
UniRef50_Q3S8E5 Cluster: Putative D-isomer specific 2-hydroxyaci... 36 0.67
UniRef50_Q1Q6E5 Cluster: Putative uncharacterized protein; n=1; ... 36 0.67
UniRef50_A5ZQ76 Cluster: Putative uncharacterized protein; n=2; ... 36 0.67
UniRef50_A5EBI0 Cluster: Putative General secretion pathway prot... 36 0.67
UniRef50_A2EKB2 Cluster: Serine/threonine-protein kinase C, puta... 36 0.67
UniRef50_Q8NIV8 Cluster: Putative uncharacterized protein B13H18... 36 0.67
UniRef50_Q6CFF2 Cluster: Yarrowia lipolytica chromosome B of str... 36 0.67
UniRef50_O14075 Cluster: Putative 2-hydroxyacid dehydrogenase UN... 36 0.67
UniRef50_Q2JXI7 Cluster: Putative lipoprotein; n=1; Synechococcu... 36 0.88
UniRef50_Q2INP8 Cluster: Tetratricopeptide repeat protein; n=1; ... 36 0.88
UniRef50_Q0RE68 Cluster: Putative uncharacterized protein; n=1; ... 36 0.88
UniRef50_A7RV09 Cluster: Predicted protein; n=1; Nematostella ve... 36 0.88
UniRef50_Q7S973 Cluster: Predicted protein; n=1; Neurospora cras... 36 0.88
UniRef50_Q5AUK0 Cluster: Putative uncharacterized protein; n=1; ... 36 0.88
UniRef50_Q4WGA0 Cluster: RhoGAP and Fes/CIP4 domain protein; n=1... 36 0.88
UniRef50_A6S7X7 Cluster: Predicted protein; n=1; Botryotinia fuc... 36 0.88
UniRef50_Q9HSS1 Cluster: Phosphoglycerate dehydrogenase; n=1; Ha... 36 0.88
UniRef50_O32264 Cluster: Probable 2-ketogluconate reductase; n=1... 36 0.88
UniRef50_P05155 Cluster: Plasma protease C1 inhibitor precursor;... 36 0.88
UniRef50_UPI0000F1E35E Cluster: PREDICTED: similar to nucleopori... 36 1.2
UniRef50_UPI0000EB4AA8 Cluster: BCL6 co-repressor-like 1; n=3; A... 36 1.2
UniRef50_Q9L238 Cluster: Putative membrane protein; n=2; Strepto... 36 1.2
UniRef50_Q62LV8 Cluster: Glyoxylate reductase; n=53; cellular or... 36 1.2
UniRef50_Q5FSE1 Cluster: Putative uncharacterized protein; n=1; ... 36 1.2
UniRef50_Q579J7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 36 1.2
UniRef50_Q9L8L8 Cluster: Beta-1,4-xylanase XynA precursor; n=4; ... 36 1.2
UniRef50_Q8VPR8 Cluster: Putative replication initiation protein... 36 1.2
UniRef50_Q0FRD5 Cluster: Putative uncharacterized protein; n=1; ... 36 1.2
UniRef50_Q047V3 Cluster: Lactate dehydrogenase related 2-hydroxy... 36 1.2
UniRef50_A7HB83 Cluster: Serine/threonine protein kinase; n=1; A... 36 1.2
UniRef50_A5V3V7 Cluster: Sporulation domain protein precursor; n... 36 1.2
UniRef50_A4JMC1 Cluster: Putative uncharacterized protein precur... 36 1.2
UniRef50_A1K2N6 Cluster: Peptidoglycan-binding protein; n=1; Azo... 36 1.2
UniRef50_Q00TL2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 36 1.2
UniRef50_Q59FN6 Cluster: Putative GTP-binding protein RAY-like v... 36 1.2
UniRef50_Q8TFZ8 Cluster: Glycerate dehydrogenase, putative; n=1;... 36 1.2
UniRef50_Q5KKJ8 Cluster: Glyoxylate reductase, putative; n=2; Fi... 36 1.2
UniRef50_A6QXP5 Cluster: Putative uncharacterized protein; n=1; ... 36 1.2
UniRef50_UPI0000EBC89F Cluster: PREDICTED: similar to Complement... 35 1.5
UniRef50_UPI0000D9E051 Cluster: PREDICTED: glyoxylate reductase/... 35 1.5
UniRef50_UPI0000584408 Cluster: PREDICTED: hypothetical protein;... 35 1.5
UniRef50_UPI0000660ED5 Cluster: Homolog of Brachydanio rerio "Kh... 35 1.5
UniRef50_Q9JKS4-3 Cluster: Isoform 3 of Q9JKS4 ; n=5; Eutheria|R... 35 1.5
UniRef50_Q6NUX3 Cluster: Im:7137941 protein; n=3; Danio rerio|Re... 35 1.5
UniRef50_Q5YQH1 Cluster: Putative uncharacterized protein; n=2; ... 35 1.5
UniRef50_Q7WYN2 Cluster: Cellulosomal scaffoldin anchoring prote... 35 1.5
UniRef50_Q1LFJ5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 35 1.5
UniRef50_Q0RPA4 Cluster: Putative D-isomer specific 2-hydroxyaci... 35 1.5
UniRef50_A6DBV6 Cluster: D-lactate dehydrogenase; n=1; Caminibac... 35 1.5
UniRef50_A4AG08 Cluster: Putative uncharacterized protein; n=1; ... 35 1.5
UniRef50_A2SEV8 Cluster: Phosphoglycerate dehydrogenase-related ... 35 1.5
UniRef50_Q2QV86 Cluster: Expressed protein; n=2; Oryza sativa|Re... 35 1.5
UniRef50_Q8T1E6 Cluster: Similar to Mus musculus (Mouse). GABA-A... 35 1.5
UniRef50_UPI0001554E41 Cluster: PREDICTED: similar to PSD4 prote... 35 2.0
UniRef50_UPI0000E26021 Cluster: PREDICTED: hypothetical protein;... 35 2.0
UniRef50_Q4RQ25 Cluster: Chromosome 17 SCAF15006, whole genome s... 35 2.0
UniRef50_A7IVQ2 Cluster: Putative uncharacterized protein B027L;... 35 2.0
UniRef50_Q7MV92 Cluster: Glycerate dehydrogenase; n=1; Porphyrom... 35 2.0
UniRef50_Q4URU0 Cluster: Putative uncharacterized protein; n=8; ... 35 2.0
UniRef50_Q39LV0 Cluster: Putative uncharacterized protein; n=1; ... 35 2.0
UniRef50_Q7CRE3 Cluster: AGR_L_3553p; n=2; Agrobacterium tumefac... 35 2.0
UniRef50_Q5IW39 Cluster: Putative PhpE; n=2; Actinomycetales|Rep... 35 2.0
UniRef50_Q0RAM3 Cluster: Putative uncharacterized protein; n=1; ... 35 2.0
UniRef50_Q03XJ7 Cluster: 2-hydroxyacid dehydrogenase; n=3; Lacto... 35 2.0
UniRef50_A5WBM9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 35 2.0
UniRef50_A4U158 Cluster: D-isomer specific 2-hydroxyacid dehydro... 35 2.0
UniRef50_A3Y8S3 Cluster: Putative uncharacterized protein; n=1; ... 35 2.0
UniRef50_A1W398 Cluster: Putative uncharacterized protein; n=2; ... 35 2.0
UniRef50_A1FGW0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 35 2.0
UniRef50_Q8MR05 Cluster: LD48009p; n=11; Coelomata|Rep: LD48009p... 35 2.0
UniRef50_Q55ML3 Cluster: Putative uncharacterized protein; n=2; ... 35 2.0
UniRef50_O14465 Cluster: D-mandelate dehydrogenase; n=1; Rhodoto... 35 2.0
UniRef50_A4R2D8 Cluster: Putative uncharacterized protein; n=1; ... 35 2.0
UniRef50_A1CP94 Cluster: Glycerate dehydrogenase; n=4; Trichocom... 35 2.0
UniRef50_UPI000155C576 Cluster: PREDICTED: similar to receptor-i... 34 2.7
UniRef50_UPI00005A516D Cluster: PREDICTED: hypothetical protein ... 34 2.7
UniRef50_UPI000065CFE1 Cluster: Homeobox protein cut-like 2 (Hom... 34 2.7
UniRef50_Q608J7 Cluster: Cellulose-binding domain protein; n=1; ... 34 2.7
UniRef50_Q1VRN5 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 34 2.7
UniRef50_Q0SG46 Cluster: Possible DNA helicase; n=2; Rhodococcus... 34 2.7
UniRef50_A6W856 Cluster: Peptidoglycan-binding LysM; n=1; Kineoc... 34 2.7
UniRef50_A5MYX9 Cluster: Putative uncharacterized protein; n=1; ... 34 2.7
UniRef50_A1GAK7 Cluster: Putative uncharacterized protein; n=1; ... 34 2.7
UniRef50_A0H5V3 Cluster: Dihydrolipoamide S-succinyltransferase;... 34 2.7
UniRef50_Q54XA2 Cluster: Putative uncharacterized protein; n=1; ... 34 2.7
UniRef50_A4IBW1 Cluster: Putative uncharacterized protein; n=2; ... 34 2.7
>UniRef50_UPI0000DB72A4 Cluster: PREDICTED: similar to
3-phosphoglycerate dehydrogenase; n=1; Apis
mellifera|Rep: PREDICTED: similar to 3-phosphoglycerate
dehydrogenase - Apis mellifera
Length = 478
Score = 107 bits (257), Expect = 2e-22
Identities = 49/79 (62%), Positives = 63/79 (79%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG GVDNID+++A +KGV V+N PG N++SACELTC L+ LAR+V A +LK GRWD
Sbjct: 74 RAGTGVDNIDLEAATRKGVIVLNTPGGNSISACELTCALISNLARNVTQAVQSLKDGRWD 133
Query: 461 RALYTGSELAGKTLAILAL 517
R LY+G EL+GKTLA+L +
Sbjct: 134 RKLYSGFELSGKTLAVLGM 152
Score = 68.1 bits (159), Expect = 2e-10
Identities = 35/70 (50%), Positives = 47/70 (67%)
Frame = +3
Query: 63 MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTK 242
M ++SVLI D V A C ELL +GI TTK K+SKE+L+ E+ NH+ L+VRS T+VT
Sbjct: 1 MSTTLRSVLISDPVDACCGELLVRHGIPVTTKYKLSKEKLIKELQNHEGLIVRSETKVTA 60
Query: 243 EVLDQA*SLR 272
+V +LR
Sbjct: 61 DVFACCPNLR 70
Score = 65.7 bits (153), Expect = 1e-09
Identities = 26/54 (48%), Positives = 38/54 (70%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
LG+GR+GR V RM A+GM +I FDP ++++ + K L++IWP+ADYIT
Sbjct: 150 LGMGRIGREVTRRMQAYGMRVIAFDPLLTSEDANYLNVEKFSLDEIWPMADYIT 203
>UniRef50_UPI00015B605A Cluster: PREDICTED: similar to GA19489-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA19489-PA - Nasonia vitripennis
Length = 511
Score = 100 bits (240), Expect = 3e-20
Identities = 43/77 (55%), Positives = 58/77 (75%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG GVDNID+ +A + G+ V+N PG N++SACELTC ++ LAR+VV A ++K GRWD
Sbjct: 74 RAGTGVDNIDIPAATRNGILVLNTPGGNSVSACELTCAVISALARNVVQAGQSMKEGRWD 133
Query: 461 RALYTGSELAGKTLAIL 511
R LY G EL+GK L ++
Sbjct: 134 RKLYAGRELSGKALGVV 150
Score = 72.1 bits (169), Expect = 1e-11
Identities = 33/70 (47%), Positives = 51/70 (72%)
Frame = +3
Query: 63 MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTK 242
M V+++SVL+ D V +CA LL ++G+ TTK K+SKEEL+ E+ HD L+VRS T+VT
Sbjct: 1 MSVNLRSVLVSDPVDERCAALLTSHGVPVTTKYKLSKEELINELQKHDGLIVRSETKVTA 60
Query: 243 EVLDQA*SLR 272
+V+ + +L+
Sbjct: 61 DVIAASPNLK 70
Score = 72.1 bits (169), Expect = 1e-11
Identities = 34/54 (62%), Positives = 39/54 (72%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+G GR+GR VA RM AFGM II +DPF + +Q AQ TK ELEDIW ADYIT
Sbjct: 150 VGFGRIGREVAHRMKAFGMEIIAYDPFFTKEQAAQIGVTKGELEDIWKNADYIT 203
>UniRef50_O43175 Cluster: D-3-phosphoglycerate dehydrogenase; n=53;
Bilateria|Rep: D-3-phosphoglycerate dehydrogenase - Homo
sapiens (Human)
Length = 533
Score = 93.1 bits (221), Expect = 6e-18
Identities = 40/79 (50%), Positives = 59/79 (74%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG GVDN+D+++A +KG+ V+N P N+LSA ELTC +++ LAR + A+ ++K G+W+
Sbjct: 75 RAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWE 134
Query: 461 RALYTGSELAGKTLAILAL 517
R + G+EL GKTL IL L
Sbjct: 135 RKKFMGTELNGKTLGILGL 153
Score = 71.7 bits (168), Expect = 1e-11
Identities = 31/54 (57%), Positives = 40/54 (74%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
LGLGR+GR VATRM +FGM IG+DP +S + A F ++ LE+IWPL D+IT
Sbjct: 151 LGLGRIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLPLEEIWPLCDFIT 204
Score = 52.4 bits (120), Expect = 1e-05
Identities = 25/67 (37%), Positives = 43/67 (64%)
Frame = +3
Query: 72 DIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 251
+++ VLI D + C ++L G+ K +SKEEL+ E+ + + L+VRSAT+VT +V+
Sbjct: 5 NLRKVLISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVI 64
Query: 252 DQA*SLR 272
+ A L+
Sbjct: 65 NAAEKLQ 71
>UniRef50_Q3AQU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Chlorobium/Pelodictyon group|Rep: D-3-phosphoglycerate
dehydrogenase - Chlorobium chlorochromatii (strain CaD3)
Length = 538
Score = 92.3 bits (219), Expect = 1e-17
Identities = 40/79 (50%), Positives = 57/79 (72%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG GVDNID+++A ++G+ V++ PG NA+SA E TC ++L ARH+ A LK G W+
Sbjct: 81 RAGTGVDNIDLEAATRQGIVVMSTPGGNAVSAAEHTCAMLLAAARHIPQAMADLKQGNWN 140
Query: 461 RALYTGSELAGKTLAILAL 517
+ LY G EL GKTL+++ L
Sbjct: 141 KHLYAGIELEGKTLSLIGL 159
Score = 48.0 bits (109), Expect = 2e-04
Identities = 25/63 (39%), Positives = 37/63 (58%)
Frame = +3
Query: 72 DIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 251
++ VLI D V +C LL +G T K +S +EL I +++ L+VRSAT + EVL
Sbjct: 11 NVMKVLITDSVHPQCGRLLLQHGFEVTEKPSLSPKELHAIIADYNILIVRSATSLPAEVL 70
Query: 252 DQA 260
+A
Sbjct: 71 AKA 73
Score = 46.0 bits (104), Expect = 8e-04
Identities = 24/54 (44%), Positives = 31/54 (57%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+GLGRVGR VA RM AFGM I +DP ++ + A + L + AD IT
Sbjct: 157 IGLGRVGREVAMRMQAFGMRTIAYDPAIADEDAALLDIELLPLHENLLRADVIT 210
>UniRef50_A1SM51 Cluster: D-3-phosphoglycerate dehydrogenase; n=15;
Actinobacteria (class)|Rep: D-3-phosphoglycerate
dehydrogenase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 536
Score = 91.9 bits (218), Expect = 1e-17
Identities = 44/79 (55%), Positives = 55/79 (69%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG G+DN+DV +A + GV V+NAP +N +SA EL LML ARH+ PA ALK G W
Sbjct: 79 RAGVGLDNVDVRAATQAGVMVVNAPTSNIVSAAELAVALMLAAARHISPAHAALKNGEWK 138
Query: 461 RALYTGSELAGKTLAILAL 517
RA YTG+EL KT+ I+ L
Sbjct: 139 RARYTGTELYEKTVGIVGL 157
Score = 49.6 bits (113), Expect = 7e-05
Identities = 22/54 (40%), Positives = 36/54 (66%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+GLGR+G VA R+ AFGM I+ +DP+V A + AQ ++L+ + AD+++
Sbjct: 155 VGLGRIGVLVAQRLSAFGMKIVAYDPYVQAGRAAQMGVRLVDLDTLLAEADFMS 208
>UniRef50_A7SFV8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 487
Score = 91.5 bits (217), Expect = 2e-17
Identities = 44/79 (55%), Positives = 54/79 (68%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG GVDNID +A GV V+N PG N LSA E TC L+ LARH+ AS + K G+W+
Sbjct: 75 RAGTGVDNIDTVAASLHGVLVMNTPGGNTLSAAEHTCALISSLARHIPQASASTKEGKWE 134
Query: 461 RALYTGSELAGKTLAILAL 517
R + G+EL GKTLAI+ L
Sbjct: 135 RKQFMGNELFGKTLAIIGL 153
Score = 67.3 bits (157), Expect = 3e-10
Identities = 30/54 (55%), Positives = 38/54 (70%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+GLGR+GR VA RM ++G+ IG+DP VS A+ + ME E IWPLADYIT
Sbjct: 151 IGLGRIGREVALRMQSYGVKTIGYDPLVSPQDAAESNIEWMETEKIWPLADYIT 204
Score = 61.7 bits (143), Expect = 2e-08
Identities = 28/68 (41%), Positives = 45/68 (66%)
Frame = +3
Query: 69 VDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEV 248
+++K VLI D V + C +L G+ K+SKEEL+ EIP +D L+VRSAT+V+++V
Sbjct: 4 LELKRVLISDSVDSCCKTILERNGVTVDVNTKLSKEELVSEIPKYDGLIVRSATKVSEDV 63
Query: 249 LDQA*SLR 272
+ +L+
Sbjct: 64 IKAGKNLK 71
>UniRef50_Q58424 Cluster: D-3-phosphoglycerate dehydrogenase; n=7;
Euryarchaeota|Rep: D-3-phosphoglycerate dehydrogenase -
Methanococcus jannaschii
Length = 524
Score = 91.1 bits (216), Expect = 2e-17
Identities = 42/79 (53%), Positives = 57/79 (72%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG GVDNIDV++A +KG+ V+NAP A+++S ELT LML AR++ A+ +LK G WD
Sbjct: 69 RAGVGVDNIDVEAATEKGIIVVNAPDASSISVAELTMGLMLAAARNIPQATASLKRGEWD 128
Query: 461 RALYTGSELAGKTLAILAL 517
R + G EL GKTL ++ L
Sbjct: 129 RKRFKGIELYGKTLGVIGL 147
Score = 45.6 bits (103), Expect = 0.001
Identities = 21/55 (38%), Positives = 34/55 (61%), Gaps = 1/55 (1%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKM-ELEDIWPLADYIT 669
+GLGR+G+ V R AFGMNIIG+DP++ + + ++ ++ AD+IT
Sbjct: 145 IGLGRIGQQVVKRAKAFGMNIIGYDPYIPKEVAESMGVELVDDINELCKRADFIT 199
Score = 41.5 bits (93), Expect = 0.018
Identities = 22/63 (34%), Positives = 38/63 (60%)
Frame = +3
Query: 84 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDQA* 263
+L+ D + ++L G ++KEELL +I + D LVVRS T+VT++V+++A
Sbjct: 4 ILVTDPLHEDAIKILEEVGEVEVATG-LTKEELLEKIKDADVLVVRSGTKVTRDVIEKAE 62
Query: 264 SLR 272
L+
Sbjct: 63 KLK 65
>UniRef50_Q3ZX05 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Dehalococcoides|Rep: D-3-phosphoglycerate dehydrogenase
- Dehalococcoides sp. (strain CBDB1)
Length = 526
Score = 88.6 bits (210), Expect = 1e-16
Identities = 42/79 (53%), Positives = 55/79 (69%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG GVDNID+ +A G+ V+NAP N +SA E T LML +ARH+ A+ +LK+G+W
Sbjct: 69 RAGVGVDNIDLKTATGNGIIVVNAPTGNTISATEHTLALMLAMARHIPRANASLKSGQWK 128
Query: 461 RALYTGSELAGKTLAILAL 517
R + GSEL GKTL I+ L
Sbjct: 129 RNEFVGSELKGKTLGIVGL 147
Score = 47.6 bits (108), Expect = 3e-04
Identities = 20/54 (37%), Positives = 32/54 (59%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+GLG +G +A R A M +IG+DPF+S ++ + + ED+ AD+IT
Sbjct: 145 VGLGNIGSEIAKRALALEMRVIGYDPFISMERAKKLQVELLPFEDLLKRADFIT 198
Score = 35.9 bits (79), Expect = 0.88
Identities = 21/60 (35%), Positives = 32/60 (53%)
Frame = +3
Query: 75 IKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 254
+K VL+ D + A L K + EEL+ I +DAL+VRS TQVT ++++
Sbjct: 1 MKKVLVSDALSATGLAPLKEIA-QVDVKTGLKPEELISIIGEYDALLVRSQTQVTADIIN 59
>UniRef50_A0LMX1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep:
D-3-phosphoglycerate dehydrogenase - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 525
Score = 87.4 bits (207), Expect = 3e-16
Identities = 40/79 (50%), Positives = 55/79 (69%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG GVDNIDV +A +G V+N PGANA +A E T +ML LARH+ A+ +++ GRWD
Sbjct: 70 RAGTGVDNIDVKAASARGALVMNTPGANATAAAEHTIAMMLALARHIPQATQSMREGRWD 129
Query: 461 RALYTGSELAGKTLAILAL 517
+ + G+EL +TL I+ L
Sbjct: 130 KKRFMGTELFHQTLGIIGL 148
Score = 38.7 bits (86), Expect = 0.13
Identities = 22/64 (34%), Positives = 37/64 (57%), Gaps = 1/64 (1%)
Frame = +3
Query: 84 VLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDQA 260
VLI DG+ +L A GI + EE+ +P++DA++VRS T++T E+++ A
Sbjct: 3 VLICDGMHEVGLSILRAAEGIDVDVPDQPGAEEIKAMLPDYDAVIVRSRTRITAELIENA 62
Query: 261 *SLR 272
L+
Sbjct: 63 PRLK 66
Score = 37.1 bits (82), Expect = 0.38
Identities = 15/54 (27%), Positives = 32/54 (59%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+GLG++G VA R + M+++G DP++ + A + L+++ +D++T
Sbjct: 146 IGLGKIGSIVADRALSMKMDVLGHDPYIIPEAAAILGVEWVPLDELLARSDFLT 199
>UniRef50_Q1IVI0 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Acidobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Acidobacteria bacterium (strain Ellin345)
Length = 531
Score = 86.6 bits (205), Expect = 5e-16
Identities = 39/79 (49%), Positives = 56/79 (70%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG GVDNI++++A +KG+ V+N PGANA++ E T LML LAR + A+ + AG+W+
Sbjct: 71 RAGVGVDNIELEAATRKGIAVMNTPGANAIAVAEHTIGLMLALARFIPRATETMHAGKWE 130
Query: 461 RALYTGSELAGKTLAILAL 517
+ G+EL GKTL I+ L
Sbjct: 131 KKSLQGTELRGKTLGIVGL 149
Score = 42.3 bits (95), Expect = 0.010
Identities = 20/54 (37%), Positives = 31/54 (57%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+GLGR+G VA R +FGM ++ DP+VS + +++ +ADYIT
Sbjct: 147 VGLGRIGLEVARRAASFGMTLVAHDPYVSPAIAHDAKIRLADRDEVLAVADYIT 200
>UniRef50_Q0W4A2 Cluster: D-3-phosphoglycerate dehydrogenase; n=11;
cellular organisms|Rep: D-3-phosphoglycerate
dehydrogenase - Uncultured methanogenic archaeon RC-I
Length = 526
Score = 86.6 bits (205), Expect = 5e-16
Identities = 36/79 (45%), Positives = 58/79 (73%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG G+DN+DV +A +KG+ V NAP N ++ACE T ++ML ++R++ A+ +LK+G+W+
Sbjct: 70 RAGVGIDNVDVPAATEKGIIVANAPEGNTIAACEHTLSMMLAMSRNIPQANASLKSGKWE 129
Query: 461 RALYTGSELAGKTLAILAL 517
R+ + G E+ KTL I+ L
Sbjct: 130 RSKFMGVEVMNKTLGIIGL 148
Score = 49.6 bits (113), Expect = 7e-05
Identities = 20/54 (37%), Positives = 34/54 (62%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+GLGR+G + R +FGM ++ +DPF +A++ Q L++I+ AD+IT
Sbjct: 146 IGLGRIGGEITKRARSFGMEVLAYDPFTTAERAQQIGARLTTLDEIYEKADFIT 199
Score = 45.2 bits (102), Expect = 0.001
Identities = 20/57 (35%), Positives = 40/57 (70%), Gaps = 1/57 (1%)
Frame = +3
Query: 84 VLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 251
VL+ D + + ++L + G+ + +++KE+L+ +I +++AL++RS TQVTKEV+
Sbjct: 3 VLVTDPISEEGIKILKSEPGVQVDIETRLTKEQLIEKIKDYNALIIRSETQVTKEVI 59
>UniRef50_Q9X1C1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Thermotogaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Thermotoga maritima
Length = 306
Score = 86.2 bits (204), Expect = 6e-16
Identities = 39/77 (50%), Positives = 52/77 (67%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG G+DNIDV A +KG+ V+N PGA+A S EL LML ARH+ A+ +LK G+W+
Sbjct: 72 RAGIGLDNIDVQKAKEKGIKVLNTPGASAPSVAELAMGLMLACARHIARATVSLKEGKWE 131
Query: 461 RALYTGSELAGKTLAIL 511
+ G EL GKTL ++
Sbjct: 132 KKALKGKELLGKTLGLI 148
Score = 38.3 bits (85), Expect = 0.17
Identities = 21/63 (33%), Positives = 35/63 (55%)
Frame = +3
Query: 84 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDQA* 263
V + D + + +LL T + K+EL+ IP D LVVRSAT+VT ++++
Sbjct: 6 VHVNDPLDKEATQLLMNKEELEVTSEHLEKDELMKIIPEVDVLVVRSATKVTADIIEAGK 65
Query: 264 SLR 272
+L+
Sbjct: 66 NLK 68
Score = 34.3 bits (75), Expect = 2.7
Identities = 14/26 (53%), Positives = 18/26 (69%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDP 585
+G G +G+ VA R AFGM II +DP
Sbjct: 148 IGFGNIGQEVAKRALAFGMKIIAYDP 173
>UniRef50_P35136 Cluster: D-3-phosphoglycerate dehydrogenase; n=8;
Bacillaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus subtilis
Length = 525
Score = 86.2 bits (204), Expect = 6e-16
Identities = 41/79 (51%), Positives = 52/79 (65%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG GVDNID+D A K GV VINAP N +S E T ++ L RH+ A+ ++K+ W+
Sbjct: 68 RAGVGVDNIDIDEATKHGVIVINAPNGNTISTAEHTFAMISSLMRHIPQANISVKSREWN 127
Query: 461 RALYTGSELAGKTLAILAL 517
R Y GSEL GKTL I+ L
Sbjct: 128 RTAYVGSELYGKTLGIVGL 146
Score = 43.6 bits (98), Expect = 0.004
Identities = 20/54 (37%), Positives = 31/54 (57%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+GLGR+G +A R AFGM + FDPF++ ++ + E++ AD IT
Sbjct: 144 VGLGRIGSEIAQRRGAFGMTVHVFDPFLTEERAKKIGVNSRTFEEVLESADIIT 197
>UniRef50_A6C9V4 Cluster: Phosphoglycerate dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: Phosphoglycerate
dehydrogenase - Planctomyces maris DSM 8797
Length = 541
Score = 85.8 bits (203), Expect = 8e-16
Identities = 39/79 (49%), Positives = 54/79 (68%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG GVDNID +A ++G+ V+N P N S E T LM+ LAR++ PA +K G+W+
Sbjct: 71 RAGVGVDNIDRAAATREGIVVMNTPAGNTTSTAEQTIALMMALARNIGPAYATMKEGKWE 130
Query: 461 RALYTGSELAGKTLAILAL 517
R TG+++AGKTLAI+ L
Sbjct: 131 RKKLTGTQVAGKTLAIIGL 149
Score = 43.2 bits (97), Expect = 0.006
Identities = 20/55 (36%), Positives = 35/55 (63%), Gaps = 1/55 (1%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHC-TKMELEDIWPLADYIT 669
+GLGR+G VA R M +IG+DPF+SA++ A++ E++++ D++T
Sbjct: 147 IGLGRIGLSVAHRAQGLEMKVIGYDPFMSAERAAEYGIELYKEVDELVKHCDFLT 201
>UniRef50_A7HDB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Anaeromyxobacter sp. Fw109-5
Length = 528
Score = 85.4 bits (202), Expect = 1e-15
Identities = 34/79 (43%), Positives = 59/79 (74%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG GVDN+D+ +A ++GV V+N PG ++++ EL +++L L+RHV A+ ++KAG+W+
Sbjct: 71 RAGVGVDNVDLAAATRRGVVVMNTPGGSSITVAELALSMILALSRHVAAATGSVKAGKWE 130
Query: 461 RALYTGSELAGKTLAILAL 517
+ + G ELAG+TL ++ +
Sbjct: 131 KKRFQGHELAGRTLGVVGI 149
Score = 49.2 bits (112), Expect = 9e-05
Identities = 18/54 (33%), Positives = 34/54 (62%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+G+G +G + R A GM ++ FDPF+SA+ A+ + ++L+ +W AD ++
Sbjct: 147 VGIGNIGSVLVARAVALGMRVVAFDPFISAEAAAKLGASLVDLDTLWREADVVS 200
>UniRef50_A6UQN3 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Methanococcus|Rep: D-3-phosphoglycerate dehydrogenase -
Methanococcus vannielii SB
Length = 523
Score = 85.0 bits (201), Expect = 1e-15
Identities = 40/79 (50%), Positives = 55/79 (69%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG GVDN+D+D+A +KGV V+NAP A+++S EL LML AR++ A+ +LK G WD
Sbjct: 69 RAGVGVDNVDLDAATEKGVVVVNAPDASSISVAELMFGLMLSAARNIPQATASLKKGEWD 128
Query: 461 RALYTGSELAGKTLAILAL 517
R + G E+ KTL I+ L
Sbjct: 129 RKSFKGMEVYAKTLGIVGL 147
Score = 43.6 bits (98), Expect = 0.004
Identities = 17/54 (31%), Positives = 35/54 (64%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+GLGR+G+ VA R AF MNI+ +DP++ + ++ + ++++ +++IT
Sbjct: 145 VGLGRIGQQVAKRAQAFEMNIVAYDPYIPENVASELGIKLLSVDELCAESEFIT 198
Score = 42.3 bits (95), Expect = 0.010
Identities = 25/63 (39%), Positives = 36/63 (57%)
Frame = +3
Query: 84 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDQA* 263
+LI D + E+L G IS EE+ +I + DALVVRS T VTKE++D +
Sbjct: 4 ILITDPLHESAIEILKEAGEVEIATG-ISIEEIKQKIKDADALVVRSGTTVTKEIIDASE 62
Query: 264 SLR 272
+L+
Sbjct: 63 NLK 65
>UniRef50_A0L7J1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Magnetococcus sp. (strain MC-1)
Length = 527
Score = 84.6 bits (200), Expect = 2e-15
Identities = 36/79 (45%), Positives = 54/79 (68%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG GVDN+D +A +KG+ V+N P NA++ EL TL + ARH+ A+ + KAG+W+
Sbjct: 70 RAGIGVDNVDTPAASQKGIIVMNTPFGNAITTAELGVTLAMAAARHIPAATASTKAGKWE 129
Query: 461 RALYTGSELAGKTLAILAL 517
++ + G ELAGKT ++ L
Sbjct: 130 KSRFMGRELAGKTAGVIGL 148
Score = 50.0 bits (114), Expect = 5e-05
Identities = 21/55 (38%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKME-LEDIWPLADYIT 669
+GLG VGR VA R+ M ++ +DPF++ D+ ++ LED+WP D +T
Sbjct: 146 IGLGNVGRLVAQRLAGLDMKVVAYDPFINKDRAISLGLEMVDKLEDLWPRVDLLT 200
Score = 38.3 bits (85), Expect = 0.17
Identities = 20/63 (31%), Positives = 33/63 (52%)
Frame = +3
Query: 84 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDQA* 263
VLI D + E+ A G+ K +S +ELL I +D + +RSAT++ + + A
Sbjct: 4 VLIADKMSPMAEEVFRARGLEVDVKVGMSPDELLACIDQYDGIAIRSATRLPAQAIAAAS 63
Query: 264 SLR 272
L+
Sbjct: 64 RLK 66
>UniRef50_Q897N8 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Clostridiales|Rep: D-3-phosphoglycerate dehydrogenase -
Clostridium tetani
Length = 533
Score = 84.2 bits (199), Expect = 3e-15
Identities = 39/79 (49%), Positives = 51/79 (64%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG GVDNID+ A K+G+ V N P +N +SACELT L+L +R++ LK G WD
Sbjct: 73 RAGNGVDNIDIPEATKRGIIVANTPDSNTISACELTIGLLLAQSRNIAKTDRFLKEGNWD 132
Query: 461 RALYTGSELAGKTLAILAL 517
R + G+EL KTL I+ L
Sbjct: 133 RDSFMGTELFNKTLGIIGL 151
Score = 54.0 bits (124), Expect = 3e-06
Identities = 25/55 (45%), Positives = 39/55 (70%), Gaps = 1/55 (1%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKME-LEDIWPLADYIT 669
+GLGR+G VATRM AF M +I +DP++S ++ +F+ K + LED+ +D+IT
Sbjct: 149 IGLGRIGSLVATRMNAFDMKVIAYDPYISDERFKRFNVEKKDTLEDLLKESDFIT 203
Score = 40.7 bits (91), Expect = 0.031
Identities = 23/69 (33%), Positives = 38/69 (55%), Gaps = 1/69 (1%)
Frame = +3
Query: 69 VDIKSVLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKE 245
+D +LIVD + K ELL + K + +E+LL I N+D L++RS T + E
Sbjct: 1 MDKAKILIVDKIDTKGIELLESEPNFEVDIKMGLEREKLLNIIENYDGLIIRSDTNIDIE 60
Query: 246 VLDQA*SLR 272
+++ A L+
Sbjct: 61 LMNMAKKLK 69
>UniRef50_A5UQ03 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Chloroflexi (class)|Rep: D-3-phosphoglycerate
dehydrogenase - Roseiflexus sp. RS-1
Length = 524
Score = 84.2 bits (199), Expect = 3e-15
Identities = 36/79 (45%), Positives = 58/79 (73%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG GVDNID+++A ++G+ V+NAP +N+++ ELT L+L LARH+ A +++ AG+W+
Sbjct: 69 RAGTGVDNIDLEAATRQGIMVVNAPASNSVAVAELTIALILSLARHIPQAHSSVVAGKWE 128
Query: 461 RALYTGSELAGKTLAILAL 517
R + G E+ KTL ++ L
Sbjct: 129 RNRFMGFEVRNKTLGLVGL 147
Score = 44.8 bits (101), Expect = 0.002
Identities = 20/54 (37%), Positives = 32/54 (59%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+GLGR+G VA R M+++ +DP VS ++ AQ T LE++ AD ++
Sbjct: 145 VGLGRIGAEVARRARGLEMHVVAYDPVVSTERAAQLGATLAPLEEVLAQADIVS 198
Score = 36.3 bits (80), Expect = 0.67
Identities = 18/39 (46%), Positives = 25/39 (64%)
Frame = +3
Query: 156 KAKISKEELLMEIPNHDALVVRSATQVTKEVLDQA*SLR 272
+ + K L+ +P +DAL+VRSAT+VT EVL LR
Sbjct: 27 RTDLDKAGLIAILPEYDALIVRSATRVTAEVLAAGTRLR 65
>UniRef50_A2U4T1 Cluster: D-3-phosphoglycerate dehydrogenase; n=14;
Bacillales|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus coagulans 36D1
Length = 541
Score = 84.2 bits (199), Expect = 3e-15
Identities = 39/77 (50%), Positives = 54/77 (70%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG GVDNIDVD+A +KG+ V+N+PG N +SA E T +ML L+R++ A + AG+W+
Sbjct: 71 RAGVGVDNIDVDAATRKGIIVVNSPGGNTISATEHTLAMMLSLSRNIPQAHKSAAAGKWE 130
Query: 461 RALYTGSELAGKTLAIL 511
R + G EL KTL I+
Sbjct: 131 REKFKGVELFKKTLGII 147
Score = 49.6 bits (113), Expect = 7e-05
Identities = 21/54 (38%), Positives = 36/54 (66%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+G G++G VA R AFGM ++G+DP+++ ++ A+ K L++I AD+IT
Sbjct: 147 IGTGKIGTEVAKRAKAFGMAVLGYDPYLTEERAAKLGIKKATLDEIAAQADFIT 200
Score = 34.7 bits (76), Expect = 2.0
Identities = 19/65 (29%), Positives = 38/65 (58%), Gaps = 1/65 (1%)
Frame = +3
Query: 81 SVLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDQ 257
++L+ D V + + L A+ + I+ E+L I +D L+VR+ T+VTK++++
Sbjct: 3 NILVTDKVSEEGLKKLYAHKDFIVEHQPGIAPEDLKATIGQYDGLIVRNQTKVTKDIIEA 62
Query: 258 A*SLR 272
+ +LR
Sbjct: 63 SGNLR 67
>UniRef50_A1DFM4 Cluster: D-3-phosphoglycerate dehydrogenase; n=10;
Fungi/Metazoa group|Rep: D-3-phosphoglycerate
dehydrogenase - Neosartorya fischeri (strain ATCC 1020 /
DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain
ATCC 1020 / DSM 3700 / NRRL 181))
Length = 582
Score = 84.2 bits (199), Expect = 3e-15
Identities = 36/79 (45%), Positives = 57/79 (72%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG GVDN+DV+ A K G+ V+N+P N +A E T L++ +AR++ A ++LK+G+W+
Sbjct: 76 RAGVGVDNVDVEEATKLGIVVVNSPSGNIGAAAEHTIALLIAMARNIPEACSSLKSGKWE 135
Query: 461 RALYTGSELAGKTLAILAL 517
R+ + G E+ GKTL+I+ L
Sbjct: 136 RSKFVGVEVKGKTLSIIGL 154
Score = 35.9 bits (79), Expect = 0.88
Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 1/55 (1%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKM-ELEDIWPLADYIT 669
+GLG+VG VA GMN+ DP+ S T + L ++ P AD++T
Sbjct: 152 IGLGKVGLTVARLAKGLGMNVNALDPYASPAVAVSASVTLVSSLSELLPTADFLT 206
Score = 34.3 bits (75), Expect = 2.7
Identities = 22/63 (34%), Positives = 34/63 (53%)
Frame = +3
Query: 84 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDQA* 263
VL+ + + LL A + + + +ELL IP ++ALVVRS T+VT +L A
Sbjct: 11 VLVPEKLSPDGLALLRA-SLEVDERRGLDADELLQIIPEYEALVVRSETKVTGNLLRAAK 69
Query: 264 SLR 272
L+
Sbjct: 70 QLK 72
>UniRef50_Q2AHU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Halothermothrix orenii H 168|Rep: D-3-phosphoglycerate
dehydrogenase - Halothermothrix orenii H 168
Length = 527
Score = 83.4 bits (197), Expect = 4e-15
Identities = 40/85 (47%), Positives = 52/85 (61%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG G DNID++ A K+G+ V N P N +SA E T +ML L+R++ A+ AL G WD
Sbjct: 69 RAGTGYDNIDIEEASKRGIIVFNTPTGNTISAVEHTIGMMLALSRNIPQANQALHEGIWD 128
Query: 461 RALYTGSELAGKTLAILALAGSADR 535
R Y G E+ GKTL I+ L R
Sbjct: 129 RKKYMGVEVKGKTLGIIGLGRIGSR 153
Score = 47.2 bits (107), Expect = 4e-04
Identities = 20/54 (37%), Positives = 34/54 (62%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+GLGR+G VA R AFGM +I DP++ ++ A+ + + +++ +DYIT
Sbjct: 145 IGLGRIGSRVAVRAQAFGMKVIANDPYLPPEKAAKINVPLLGFKEVLKKSDYIT 198
Score = 43.2 bits (97), Expect = 0.006
Identities = 25/63 (39%), Positives = 36/63 (57%)
Frame = +3
Query: 84 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDQA* 263
VL+ D + K E+L T +S+EE L I +D L+VRS T+V KE LD+A
Sbjct: 4 VLVSDNISPKGIEILEQEA-DVTFNPDLSREEFLDIIGEYDGLIVRSMTEVDKEALDKAR 62
Query: 264 SLR 272
+L+
Sbjct: 63 NLK 65
>UniRef50_Q8PW48 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Methanomicrobia|Rep: D-3-phosphoglycerate dehydrogenase
- Methanosarcina mazei (Methanosarcina frisia)
Length = 540
Score = 83.4 bits (197), Expect = 4e-15
Identities = 38/79 (48%), Positives = 54/79 (68%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG GVDN+DVD+A KKG+ V NAP N +SA E T +M+ ++R++ A+ +LKA W
Sbjct: 85 RAGVGVDNVDVDAATKKGIIVANAPEGNMISAAEHTIAMMMSMSRNIPQANASLKAREWK 144
Query: 461 RALYTGSELAGKTLAILAL 517
R + G E+ GKTL ++ L
Sbjct: 145 RNKFMGVEVKGKTLGVIGL 163
Score = 44.8 bits (101), Expect = 0.002
Identities = 21/54 (38%), Positives = 31/54 (57%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+GLGR+G VA R MN++G+DPF+S + + + +I ADYIT
Sbjct: 161 IGLGRIGSEVAKRAAGLEMNLMGYDPFISEKRAMELGVKLATVNEIAKEADYIT 214
Score = 39.5 bits (88), Expect = 0.072
Identities = 22/68 (32%), Positives = 42/68 (61%)
Frame = +3
Query: 69 VDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEV 248
+D+K VL+ D + + E+L + + ++EL+ +I +DALV+RS TQVT+ +
Sbjct: 16 IDMK-VLVSDSLSNEGLEILKEH-FDIDVCTGLCEDELVEKIKGYDALVIRSGTQVTQRI 73
Query: 249 LDQA*SLR 272
++ A +L+
Sbjct: 74 IEAADNLK 81
>UniRef50_O29445 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
cellular organisms|Rep: D-3-phosphoglycerate
dehydrogenase - Archaeoglobus fulgidus
Length = 527
Score = 83.0 bits (196), Expect = 6e-15
Identities = 36/79 (45%), Positives = 52/79 (65%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG GVDNID+++A ++G+ V+NAPG N +S E LML AR + A ++K G+W+
Sbjct: 69 RAGVGVDNIDINAATQRGIVVVNAPGGNTISTAEHAIALMLAAARKIPQADRSVKEGKWE 128
Query: 461 RALYTGSELAGKTLAILAL 517
R + G EL GKT ++ L
Sbjct: 129 RKKFMGIELRGKTAGVIGL 147
Score = 48.4 bits (110), Expect = 2e-04
Identities = 21/63 (33%), Positives = 39/63 (61%)
Frame = +3
Query: 84 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDQA* 263
VL+ + + + + + G+ K +S+EEL+ E+P ++A+VVRS T+V EV+ A
Sbjct: 3 VLVAEPISEEAIDYMRKNGLEVEVKTGMSREELIREVPKYEAIVVRSQTKVDAEVIQAAK 62
Query: 264 SLR 272
+L+
Sbjct: 63 NLK 65
Score = 44.0 bits (99), Expect = 0.003
Identities = 21/54 (38%), Positives = 32/54 (59%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+GLGRVG VA R A MN++ +DPFVS ++ Q ++ + + +D IT
Sbjct: 145 IGLGRVGFEVAKRCKALEMNVLAYDPFVSKERAEQIGVKLVDFDTLLASSDVIT 198
>UniRef50_Q1AXS3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Rubrobacter xylanophilus DSM 9941|Rep:
D-3-phosphoglycerate dehydrogenase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 527
Score = 82.6 bits (195), Expect = 8e-15
Identities = 38/79 (48%), Positives = 55/79 (69%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG GVDNID+++A K+G+ V NAP +N ++A E T LML +AR + A +L+ G W+
Sbjct: 68 RAGIGVDNIDIEAATKRGILVANAPESNTVAAAEHTLGLMLAVARRIPAADASLRRGEWN 127
Query: 461 RALYTGSELAGKTLAILAL 517
RA + G E+A KTL ++ L
Sbjct: 128 RAAFKGVEVAEKTLGLVGL 146
Score = 38.7 bits (86), Expect = 0.13
Identities = 18/55 (32%), Positives = 32/55 (58%), Gaps = 1/55 (1%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKM-ELEDIWPLADYIT 669
+GLG VG VA GM ++ +DP+VS ++ + + LE+I+ AD+++
Sbjct: 144 VGLGHVGSIVARGALGMGMRVLAYDPYVSEERMRSMNVERAGSLEEIFEEADFVS 198
Score = 36.7 bits (81), Expect = 0.51
Identities = 23/63 (36%), Positives = 34/63 (53%)
Frame = +3
Query: 84 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDQA* 263
VL+ + + + ELL +S ELL I +D L+VRSAT+VT EV++ A
Sbjct: 3 VLVTEKLAERGVELLRRE-FEVDVLLGLSPGELLERIGEYDGLIVRSATKVTAEVIEAAG 61
Query: 264 SLR 272
L+
Sbjct: 62 RLK 64
>UniRef50_Q8TYK0 Cluster: Predicted dehydrogenase related to
phosphoglycerate dehydrogenase; n=9; Archaea|Rep:
Predicted dehydrogenase related to phosphoglycerate
dehydrogenase - Methanopyrus kandleri
Length = 522
Score = 82.6 bits (195), Expect = 8e-15
Identities = 38/79 (48%), Positives = 55/79 (69%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG GVDNIDV +A ++G+ V+NAP ++++S E T L+L LAR + A +++ G WD
Sbjct: 69 RAGVGVDNIDVKAATERGIIVVNAPESSSISVAEHTMGLILALARKIPQADRSVRRGEWD 128
Query: 461 RALYTGSELAGKTLAILAL 517
R + G ELAGKTL ++ L
Sbjct: 129 RKRFMGVELAGKTLGLIGL 147
Score = 36.7 bits (81), Expect = 0.51
Identities = 18/55 (32%), Positives = 31/55 (56%), Gaps = 1/55 (1%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKM-ELEDIWPLADYIT 669
+GLGR+G+ VA R AF M + +DP++ + + ELE++ AD ++
Sbjct: 145 IGLGRIGQQVAKRAKAFEMEVTAYDPYIPEKVAEELGVELVDELEELLERADVVS 199
Score = 33.1 bits (72), Expect = 6.2
Identities = 18/63 (28%), Positives = 34/63 (53%)
Frame = +3
Query: 84 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDQA* 263
+L+ D + L G + +EE+ + + DA VVRS T+VT+E++++A
Sbjct: 4 ILVTDPIHEDALRKLEELGEVVVLE-DADEEEIREHVRDADAWVVRSGTRVTRELIEEAK 62
Query: 264 SLR 272
+L+
Sbjct: 63 NLK 65
>UniRef50_Q67TJ9 Cluster: Phosphoglycerate dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: Phosphoglycerate
dehydrogenase - Symbiobacterium thermophilum
Length = 540
Score = 82.2 bits (194), Expect = 1e-14
Identities = 41/80 (51%), Positives = 54/80 (67%), Gaps = 1/80 (1%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL-KAGRW 457
RAG GVDNIDV +A ++GV V+N PGAN S E L++ +AR++ A AL + GRW
Sbjct: 67 RAGVGVDNIDVAAATERGVVVVNVPGANTYSTAEHAFGLLIAVARNIPQAHHALAREGRW 126
Query: 458 DRALYTGSELAGKTLAILAL 517
DR + G+EL GKTL I+ L
Sbjct: 127 DRMSFVGTELHGKTLGIIGL 146
Score = 42.7 bits (96), Expect = 0.008
Identities = 20/55 (36%), Positives = 31/55 (56%), Gaps = 1/55 (1%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKM-ELEDIWPLADYIT 669
+GLGR+G VA R AFGM ++ +DP+V + T + L + P D++T
Sbjct: 144 IGLGRIGSEVAVRARAFGMRVLAYDPYVPHSRAEHLGVTLVPSLRGLLPEVDFLT 198
Score = 39.1 bits (87), Expect = 0.095
Identities = 18/30 (60%), Positives = 23/30 (76%)
Frame = +3
Query: 162 KISKEELLMEIPNHDALVVRSATQVTKEVL 251
K++ EELL IP +DAL+ RS T+VT EVL
Sbjct: 27 KVTSEELLEIIPEYDALITRSETKVTAEVL 56
>UniRef50_Q8UJZ6 Cluster: Phosphoglycerate dehydrogenase; n=3;
Alphaproteobacteria|Rep: Phosphoglycerate dehydrogenase
- Agrobacterium tumefaciens (strain C58 / ATCC 33970)
Length = 354
Score = 81.4 bits (192), Expect = 2e-14
Identities = 35/81 (43%), Positives = 53/81 (65%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
G GVDNIDVD+A ++ + V+ A GANALS E TL+ + + +VP + ++AGRW++A
Sbjct: 101 GVGVDNIDVDAASRREIPVVVAAGANALSVAEHAITLLFAVVKRIVPLDSGIRAGRWEKA 160
Query: 467 LYTGSELAGKTLAILALAGSA 529
Y+G ELAG + ++ A
Sbjct: 161 GYSGKELAGMIIGLVGFGAIA 181
>UniRef50_Q1PZY1 Cluster: Similar to D-3-phosphoglycerate
dehydrogenase; n=1; Candidatus Kuenenia
stuttgartiensis|Rep: Similar to D-3-phosphoglycerate
dehydrogenase - Candidatus Kuenenia stuttgartiensis
Length = 535
Score = 81.4 bits (192), Expect = 2e-14
Identities = 37/79 (46%), Positives = 51/79 (64%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG GVDNIDV +A KKG+ V+N P N +S E T L+ L+R V A ++K G+W+
Sbjct: 78 RAGVGVDNIDVPAATKKGIVVMNTPAGNIISTAEHTIALLCSLSRFVPQACASVKEGKWE 137
Query: 461 RALYTGSELAGKTLAILAL 517
+ +TG +L GKT I+ L
Sbjct: 138 KKKFTGQQLTGKTFGIIGL 156
Score = 51.2 bits (117), Expect = 2e-05
Identities = 27/56 (48%), Positives = 36/56 (64%), Gaps = 2/56 (3%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQF--HCTKMELEDIWPLADYIT 669
+GLGRVGR VA R A M +IG+DPF++ + +Q+ H K L D+ ADYIT
Sbjct: 154 IGLGRVGRQVAKRAAALEMKVIGYDPFITTEISSQYNIHIVK-NLRDLLAQADYIT 208
Score = 36.3 bits (80), Expect = 0.67
Identities = 21/63 (33%), Positives = 33/63 (52%)
Frame = +3
Query: 84 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDQA* 263
VLI D + C E+L G+ K + EL I D ++VRS T++T VL+++
Sbjct: 12 VLIADDLPDVCNEILQNAGVEVLKKTGLKPPELDAVIKMCDGVIVRSNTKLTAPVLEKSE 71
Query: 264 SLR 272
L+
Sbjct: 72 KLK 74
>UniRef50_O04130 Cluster: D-3-phosphoglycerate dehydrogenase,
chloroplast precursor; n=13; Magnoliophyta|Rep:
D-3-phosphoglycerate dehydrogenase, chloroplast
precursor - Arabidopsis thaliana (Mouse-ear cress)
Length = 624
Score = 80.6 bits (190), Expect = 3e-14
Identities = 35/77 (45%), Positives = 53/77 (68%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG G+DN+D+ +A + G V+NAP AN ++A E L+ +AR+V A ++KAG+W+
Sbjct: 151 RAGVGIDNVDLQAATEHGCLVVNAPTANTVAAAEHGIALLASMARNVAQADASIKAGKWE 210
Query: 461 RALYTGSELAGKTLAIL 511
R+ Y G L GKTLA++
Sbjct: 211 RSKYVGVSLVGKTLAVM 227
Score = 38.7 bits (86), Expect = 0.13
Identities = 20/59 (33%), Positives = 34/59 (57%)
Frame = +3
Query: 84 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDQA 260
+L+ + +G LL +G + +S E+L ++ DAL+VRS T+VT+EV + A
Sbjct: 85 ILVTEKLGEAGVNLLREFGDVDCSY-DLSPEDLKKKVAESDALIVRSGTKVTREVFEAA 142
Score = 35.9 bits (79), Expect = 0.88
Identities = 16/54 (29%), Positives = 26/54 (48%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+G G+VG VA R GM +I DP+ AD+ + + AD+++
Sbjct: 227 MGFGKVGTEVARRAKGLGMTVISHDPYAPADRARALGVDLVSFDQAISTADFVS 280
>UniRef50_Q7UQL2 Cluster: Phosphoglycerate dehydrogenase; n=2;
Planctomycetaceae|Rep: Phosphoglycerate dehydrogenase -
Rhodopirellula baltica
Length = 540
Score = 78.6 bits (185), Expect = 1e-13
Identities = 33/79 (41%), Positives = 53/79 (67%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG G DNID +A ++G+ V+N P N +S E T ++L ++R++ A+ +L GRWD
Sbjct: 71 RAGVGTDNIDKPAATRRGIVVMNTPAGNTVSTAEHTFAMLLAMSRNIAAANQSLVEGRWD 130
Query: 461 RALYTGSELAGKTLAILAL 517
R + G+++AGKTL I+ +
Sbjct: 131 RKKFMGTQVAGKTLGIVGM 149
Score = 51.6 bits (118), Expect = 2e-05
Identities = 22/55 (40%), Positives = 37/55 (67%), Gaps = 1/55 (1%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKM-ELEDIWPLADYIT 669
+G+GR+GR VA+R AF M+++ FDPF++ DQ ++ ++D+ P DY+T
Sbjct: 147 VGMGRIGREVASRAQAFDMDVVAFDPFLTDDQAESLKVRRVATVDDMLPQIDYLT 201
>UniRef50_P73821 Cluster: D-3-phosphoglycerate dehydrogenase; n=37;
Cyanobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Synechocystis sp. (strain PCC 6803)
Length = 554
Score = 78.6 bits (185), Expect = 1e-13
Identities = 33/79 (41%), Positives = 54/79 (68%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG GVDNIDV +A ++G+ V+N+P N ++A E +M+ LARH+ A+ ++K +W+
Sbjct: 97 RAGVGVDNIDVPAATRQGIVVVNSPEGNTIAAAEHALAMMMALARHIPDANKSVKESKWE 156
Query: 461 RALYTGSELAGKTLAILAL 517
R + G+E+ KTL ++ L
Sbjct: 157 RKQFIGTEVYKKTLGVVGL 175
Score = 49.2 bits (112), Expect = 9e-05
Identities = 21/54 (38%), Positives = 36/54 (66%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+GLG++G VA A GM ++ +DPF+S ++ Q CT ++L+ ++ AD+IT
Sbjct: 173 VGLGKIGSHVAGVAKAMGMKLLAYDPFISQERADQIGCTLVDLDLLFSEADFIT 226
Score = 35.1 bits (77), Expect = 1.5
Identities = 17/63 (26%), Positives = 36/63 (57%)
Frame = +3
Query: 84 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDQA* 263
VL+ D + ++L K +S+ E++ +P +DA+++RSAT+VT++++
Sbjct: 32 VLVSDSIDQVGIDILKQVA-QVDVKTGLSEAEIIDIVPEYDAIMLRSATKVTEKIIQAGS 90
Query: 264 SLR 272
L+
Sbjct: 91 QLK 93
>UniRef50_A3EWA5 Cluster: Phosphoglycerate dehydrogenase; n=2;
Bacteria|Rep: Phosphoglycerate dehydrogenase -
Leptospirillum sp. Group II UBA
Length = 535
Score = 78.2 bits (184), Expect = 2e-13
Identities = 32/79 (40%), Positives = 57/79 (72%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAGAG+DN+D+++A ++G+ V+N PG N ++ E T +L++ +AR + A+ + KAG+W+
Sbjct: 73 RAGAGLDNVDLEAATERGIVVMNTPGGNTVTTAEHTMSLLMSMARRIPQANASNKAGKWE 132
Query: 461 RALYTGSELAGKTLAILAL 517
++ + G EL KTL I+ +
Sbjct: 133 KSKFMGVELFQKTLGIVGM 151
Score = 48.4 bits (110), Expect = 2e-04
Identities = 26/70 (37%), Positives = 38/70 (54%)
Frame = +3
Query: 63 MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTK 242
M DI+ +LI D + + G K K+S +EL EI +D LV+RS T+VT+
Sbjct: 1 MSSDIR-ILISDAISEDGVRIFQKAGFHVDMKTKLSPQELAQEISQYDGLVIRSGTKVTR 59
Query: 243 EVLDQA*SLR 272
E+L A L+
Sbjct: 60 EILKNADRLK 69
Score = 39.9 bits (89), Expect = 0.054
Identities = 17/54 (31%), Positives = 33/54 (61%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+G+G++G+ VA MNII FDP+++ + + + L++++ AD+IT
Sbjct: 149 VGMGKIGQHVAQIARGIAMNIIAFDPYLTPEVAEKSGVHPVSLDELFQRADFIT 202
>UniRef50_Q8EN61 Cluster: Phosphoglycerate dehydrogenase; n=2;
Bacillaceae|Rep: Phosphoglycerate dehydrogenase -
Oceanobacillus iheyensis
Length = 528
Score = 77.8 bits (183), Expect = 2e-13
Identities = 38/79 (48%), Positives = 52/79 (65%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG GVDNID+++A + GV V+NAP N SA E T +++ L+R++ A ALK +WD
Sbjct: 72 RAGVGVDNIDLEAATENGVIVVNAPNGNTNSAAEHTMAMIMALSRNIPQAYHALKQKQWD 131
Query: 461 RALYTGSELAGKTLAILAL 517
R + G EL KTL I+ L
Sbjct: 132 RKRFVGVELKQKTLGIVGL 150
Score = 43.6 bits (98), Expect = 0.004
Identities = 21/54 (38%), Positives = 30/54 (55%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+GLGR+G VA R MN+I +DPF + ++ Q LED+ D+IT
Sbjct: 148 VGLGRIGAEVAARAKGQRMNVIAYDPFFTEEKAEQMGVQYGTLEDVLRAGDFIT 201
Score = 33.1 bits (72), Expect = 6.2
Identities = 21/64 (32%), Positives = 38/64 (59%), Gaps = 1/64 (1%)
Frame = +3
Query: 84 VLIVDGVGAKCAE-LLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDQA 260
VLI D + + + L A I +++EL +I + DA++VRS TQVT+ ++++A
Sbjct: 5 VLISDPLSEEGLKPLQEAENIEVVINPGWNEQELSDQIDSFDAILVRSQTQVTRALIEKA 64
Query: 261 *SLR 272
+L+
Sbjct: 65 SNLK 68
>UniRef50_Q1NQ97 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=2;
Bacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - delta
proteobacterium MLMS-1
Length = 304
Score = 77.8 bits (183), Expect = 2e-13
Identities = 32/79 (40%), Positives = 53/79 (67%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG G+DN+DV +A KKGV V+NAP NA +A E ++M+ L R++ A+ ++KAG+W+
Sbjct: 69 RAGIGLDNVDVPAASKKGVVVMNAPDGNATTAAEHAVSMMMALTRNIPQATASMKAGKWE 128
Query: 461 RALYTGSELAGKTLAILAL 517
+ + G E+ K ++ +
Sbjct: 129 KKKFQGHEVTAKVAGVVGI 147
Score = 46.0 bits (104), Expect = 8e-04
Identities = 23/63 (36%), Positives = 39/63 (61%)
Frame = +3
Query: 84 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDQA* 263
VLI D + +++ G+ + +S EEL+ IP +D LV+RSA++VT E+L+ A
Sbjct: 3 VLISDNLAPVGEKIMRDAGLEVDVRTGLSPEELVKIIPAYDGLVIRSASKVTAEILEAAE 62
Query: 264 SLR 272
+L+
Sbjct: 63 NLK 65
Score = 43.6 bits (98), Expect = 0.004
Identities = 20/54 (37%), Positives = 31/54 (57%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+G+GR+GR A R M +I FDP + A+Q + + LE++ ADYI+
Sbjct: 145 VGIGRIGRIFAERAMGLRMKVIAFDPHMPAEQMEKIGVEPVTLEELCQRADYIS 198
>UniRef50_A7CYD6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Opitutaceae bacterium TAV2|Rep: D-3-phosphoglycerate
dehydrogenase - Opitutaceae bacterium TAV2
Length = 529
Score = 77.0 bits (181), Expect = 4e-13
Identities = 34/79 (43%), Positives = 54/79 (68%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG GVDN+DV++A ++GV V+N P N ++ ELT T +L +R V A+ +++ G+WD
Sbjct: 70 RAGVGVDNVDVEAATERGVVVMNTPAGNTIATAELTFTHILCGSRPVSQAAASMREGKWD 129
Query: 461 RALYTGSELAGKTLAILAL 517
R ++G EL KTL ++ +
Sbjct: 130 RKSFSGVELFKKTLGVIGM 148
Score = 46.8 bits (106), Expect = 5e-04
Identities = 20/54 (37%), Positives = 32/54 (59%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+G+GR+G VA R AFGM ++ +DP+++ + L++I ADYIT
Sbjct: 146 IGMGRIGGEVARRAVAFGMKVLAYDPYLAPSRAKAMQVEVATLDEILAQADYIT 199
>UniRef50_A7P9P5 Cluster: Chromosome chr3 scaffold_8, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr3 scaffold_8, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 653
Score = 77.0 bits (181), Expect = 4e-13
Identities = 34/77 (44%), Positives = 51/77 (66%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG G+DN+D+ +A + G V+NAP AN ++A E L+ +AR+V A ++K+G+W
Sbjct: 180 RAGVGIDNVDLAAATEHGCLVVNAPTANTVAAAEHGIALLTAMARNVAQADASVKSGKWQ 239
Query: 461 RALYTGSELAGKTLAIL 511
R Y G L GKTLA++
Sbjct: 240 RNKYVGVSLVGKTLAVM 256
Score = 36.3 bits (80), Expect = 0.67
Identities = 21/58 (36%), Positives = 34/58 (58%)
Frame = +3
Query: 81 SVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 254
+VL+ + +GA +LL + +S EEL +I DAL+VRS T+V++EV +
Sbjct: 113 TVLVAEKLGAAGLDLLKDFANVDCAY-NLSPEELCTKISLCDALIVRSGTKVSREVFE 169
Score = 35.9 bits (79), Expect = 0.88
Identities = 16/54 (29%), Positives = 28/54 (51%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+G G+VG V R GM++I DP+ +AD+ + ++ AD+I+
Sbjct: 256 MGFGKVGSEVTRRAKGLGMHVIAHDPYAAADRARAIGVELVGFDEAISTADFIS 309
>UniRef50_O67741 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Aquifex aeolicus|Rep: D-3-phosphoglycerate dehydrogenase
- Aquifex aeolicus
Length = 533
Score = 76.2 bits (179), Expect = 7e-13
Identities = 35/79 (44%), Positives = 50/79 (63%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG GVDN+D++ A K+G+ V+N PGAN + A ELT ML + R+ A ++ +WD
Sbjct: 71 RAGVGVDNVDIEEATKRGILVVNTPGANTIGATELTMMHMLTIMRNGHKAHESMLNYKWD 130
Query: 461 RALYTGSELAGKTLAILAL 517
R + G EL G+ L I+ L
Sbjct: 131 RKKFMGEELYGRILGIIGL 149
Score = 41.1 bits (92), Expect = 0.024
Identities = 26/64 (40%), Positives = 37/64 (57%), Gaps = 1/64 (1%)
Frame = +3
Query: 84 VLIVDGVGAKCAELLNAYG-IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDQA 260
VLI D + + ELL + + IS EELL I + DA++ RS T VTKE+L++A
Sbjct: 4 VLITDPIAPEGIELLQKDPEVEVYNEPDISYEELLEIIKDFDAIITRSRTPVTKELLERA 63
Query: 261 *SLR 272
L+
Sbjct: 64 EKLK 67
Score = 36.3 bits (80), Expect = 0.67
Identities = 17/55 (30%), Positives = 31/55 (56%), Gaps = 1/55 (1%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKME-LEDIWPLADYIT 669
+GLG +G VA R AFGM ++ +DP++ ++ + ++ L D+ D +T
Sbjct: 147 IGLGNIGSQVAIRAKAFGMKVMAYDPYIPREKAEKLGVKLVDNLHDMLREIDVLT 201
>UniRef50_O33116 Cluster: D-3-phosphoglycerate dehydrogenase; n=28;
Actinomycetales|Rep: D-3-phosphoglycerate dehydrogenase
- Mycobacterium leprae
Length = 528
Score = 76.2 bits (179), Expect = 7e-13
Identities = 34/79 (43%), Positives = 53/79 (67%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG G+DN+DVD+A +GV V+NAP +N SA E L+L +R + A +L+A W
Sbjct: 71 RAGVGLDNVDVDAATARGVLVVNAPTSNIHSAAEHALALLLAASRQIAEADASLRAHIWK 130
Query: 461 RALYTGSELAGKTLAILAL 517
R+ ++G+E+ GKT+ ++ L
Sbjct: 131 RSSFSGTEIFGKTVGVVGL 149
Score = 50.8 bits (116), Expect = 3e-05
Identities = 22/54 (40%), Positives = 36/54 (66%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+GLGR+G+ VA R+ AFG ++I +DP+V+ + AQ M +D+ AD+I+
Sbjct: 147 VGLGRIGQLVAARIAAFGAHVIAYDPYVAPARAAQLGIELMSFDDLLARADFIS 200
>UniRef50_A6PUG1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Victivallis vadensis
ATCC BAA-548|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Victivallis vadensis ATCC
BAA-548
Length = 524
Score = 75.8 bits (178), Expect = 9e-13
Identities = 33/79 (41%), Positives = 50/79 (63%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAGAG + ID+ A K + V+N PGAN+ + E +ML +RH++PA + + G W+
Sbjct: 69 RAGAGFNTIDIKYARKHDIDVMNTPGANSNAVAEEVVAMMLAASRHLIPADISTRKGDWE 128
Query: 461 RALYTGSELAGKTLAILAL 517
++ + G EL GKT+ IL L
Sbjct: 129 KSKFMGRELTGKTVGILGL 147
Score = 33.9 bits (74), Expect = 3.6
Identities = 14/54 (25%), Positives = 30/54 (55%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
LGLG +G+ + R+ F M ++G+DP +S + ++ I+ +D+++
Sbjct: 145 LGLGHIGQLLVKRLAGFEMKVLGYDPMLSPALADKLGVELTTVDRIFAESDFVS 198
>UniRef50_Q4L766 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Staphylococcus|Rep: D-3-phosphoglycerate dehydrogenase -
Staphylococcus haemolyticus (strain JCSC1435)
Length = 532
Score = 75.4 bits (177), Expect = 1e-12
Identities = 35/77 (45%), Positives = 51/77 (66%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG GVDNID+D+A +G+ VINAP N +SA E + ++L +AR++ A +LK W+
Sbjct: 72 RAGVGVDNIDIDAATLQGILVINAPDGNTISATEHSVAMILAMARNIPQAHASLKNKEWN 131
Query: 461 RALYTGSELAGKTLAIL 511
R + G EL KTL ++
Sbjct: 132 RKAFKGVELYQKTLGVI 148
Score = 45.6 bits (103), Expect = 0.001
Identities = 18/54 (33%), Positives = 34/54 (62%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+G GR+G VA R+ +FGM ++ +DP+++ D+ Q +++I AD++T
Sbjct: 148 IGAGRIGIGVAQRLQSFGMKVLAYDPYLTEDKAQQLGVKLATIDEIARQADFVT 201
Score = 37.1 bits (82), Expect = 0.38
Identities = 20/65 (30%), Positives = 39/65 (60%), Gaps = 1/65 (1%)
Frame = +3
Query: 81 SVLIVDGVGAKCAE-LLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDQ 257
++L+ D + + LLN K + ++ LL I +++ L+VRS TQVT++V+++
Sbjct: 4 NILVSDPISTDGLQSLLNHSDFNVDIKTDLDEQSLLDIIGDYEGLIVRSQTQVTQQVIEK 63
Query: 258 A*SLR 272
A +L+
Sbjct: 64 ASNLK 68
>UniRef50_Q8ZTC7 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Thermoproteaceae|Rep: D-3-phosphoglycerate dehydrogenase
- Pyrobaculum aerophilum
Length = 307
Score = 75.4 bits (177), Expect = 1e-12
Identities = 34/77 (44%), Positives = 50/77 (64%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R G G+DN+DV+ A KKG+ V++AP A + S ELT L+ +AR + + +KAG W
Sbjct: 69 RYGVGLDNVDVEYAVKKGIAVVSAPNAPSQSVAELTIGLLFSVARRIPLLNAKVKAGEWP 128
Query: 461 RALYTGSELAGKTLAIL 511
+ Y G E+AGKT+ I+
Sbjct: 129 KGKYIGIEIAGKTMGIV 145
Score = 39.9 bits (89), Expect = 0.054
Identities = 21/64 (32%), Positives = 34/64 (53%)
Frame = +3
Query: 81 SVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDQA 260
S LIVD V E L GI ISK++L+ I N++ L+ R ++ K+++D
Sbjct: 2 SALIVDKVDETLKERLERIGIKVDLAPGISKDDLIKIIKNYNILIFRGRLKIDKDIMDAG 61
Query: 261 *SLR 272
+L+
Sbjct: 62 QNLK 65
Score = 33.9 bits (74), Expect = 3.6
Identities = 17/54 (31%), Positives = 30/54 (55%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+G GR+GR VA + GMNI+ D + + A+ ++ LE++ +D +T
Sbjct: 145 VGFGRIGRFVAQMAKSLGMNILASDVIDVSKEVAKIGGRQVPLEELLRQSDVVT 198
>UniRef50_Q8YIU3 Cluster: D-3-PHOSPHOGLYCERATE DEHYDROGENASE; n=75;
Bacteria|Rep: D-3-PHOSPHOGLYCERATE DEHYDROGENASE -
Brucella melitensis
Length = 538
Score = 74.5 bits (175), Expect = 2e-12
Identities = 30/77 (38%), Positives = 51/77 (66%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG GVDN+D+ +A ++G+ V+N P N+++ E LM +AR + A T+ +AG+W+
Sbjct: 78 RAGIGVDNVDIPAASRRGIIVMNTPFGNSITTAEHAIALMFAVARQLPEADTSTRAGKWE 137
Query: 461 RALYTGSELAGKTLAIL 511
+ + G E+ GKTL ++
Sbjct: 138 KNRFMGVEITGKTLGVV 154
Score = 45.2 bits (102), Expect = 0.001
Identities = 20/54 (37%), Positives = 33/54 (61%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+G G +G VATR M+++ FDPF+S + + K+EL+++ AD+IT
Sbjct: 154 VGCGNIGSIVATRGIGLKMHVVAFDPFLSDARAQELGVEKVELDELLARADFIT 207
>UniRef50_A4FIF2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
D-3-phosphoglycerate dehydrogenase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 316
Score = 74.5 bits (175), Expect = 2e-12
Identities = 37/75 (49%), Positives = 52/75 (69%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
G GVDNID+D+A +G+ V+ APG+N+ + ELT LM+ AR + A TA+ AG W +
Sbjct: 78 GVGVDNIDLDAARARGIPVVFAPGSNSRAVAELTFGLMIAAARRIAAAHTAVVAGDWPK- 136
Query: 467 LYTGSELAGKTLAIL 511
LY G ELAG+TL ++
Sbjct: 137 LY-GPELAGRTLGVI 150
Score = 40.7 bits (91), Expect = 0.031
Identities = 15/54 (27%), Positives = 31/54 (57%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+G GR+GR +A AFGM ++G+DPF+ + + + + ++D+++
Sbjct: 150 IGFGRIGRLLAGYAQAFGMTVVGYDPFLDDGELTERGVRPVSFSECLAMSDFVS 203
>UniRef50_Q8R716 Cluster: Phosphoglycerate dehydrogenase and related
dehydrogenases; n=5; Clostridia|Rep: Phosphoglycerate
dehydrogenase and related dehydrogenases -
Thermoanaerobacter tengcongensis
Length = 533
Score = 74.1 bits (174), Expect = 3e-12
Identities = 37/79 (46%), Positives = 52/79 (65%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG GVDNIDV++A ++G+ V+N P N ++A ELT LML +AR++ A A G +
Sbjct: 68 RAGNGVDNIDVEAATQRGILVVNTPAGNTIAAAELTIGLMLAIARNIPQAYHAALNGDFR 127
Query: 461 RALYTGSELAGKTLAILAL 517
R + G EL GKT+ I+ L
Sbjct: 128 RDRFKGVELNGKTVGIIGL 146
Score = 44.8 bits (101), Expect = 0.002
Identities = 18/54 (33%), Positives = 36/54 (66%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+GLGR+G VA+R+ AF M +I +DP++ ++ + ++ L+++ +D+IT
Sbjct: 144 IGLGRIGSLVASRLAAFNMRVIAYDPYMPDERFEKCGVKRVTLDELLEQSDFIT 197
Score = 41.9 bits (94), Expect = 0.013
Identities = 20/63 (31%), Positives = 38/63 (60%)
Frame = +3
Query: 84 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDQA* 263
+++ + + + L Y K IS+EELL I ++DA++VRSAT+V +E++++
Sbjct: 3 IIVTEKISENGIDYLKKYA-DVDVKTNISREELLEVIKDYDAIIVRSATKVDRELIEKGE 61
Query: 264 SLR 272
L+
Sbjct: 62 KLK 64
>UniRef50_A6C2G1 Cluster: Phosphoglycerate dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: Phosphoglycerate
dehydrogenase - Planctomyces maris DSM 8797
Length = 316
Score = 74.1 bits (174), Expect = 3e-12
Identities = 36/79 (45%), Positives = 49/79 (62%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAGAG+DN+D + A +KG+ V P AN+LS ELT LML L R + A G W+
Sbjct: 71 RAGAGLDNVDTEYAHEKGIVVCFTPDANSLSVAELTIGLMLALMRKIPEARQDTLTGGWN 130
Query: 461 RALYTGSELAGKTLAILAL 517
R +TG+EL GK+ ++ L
Sbjct: 131 RLKFTGTELYGKSFGLIGL 149
Score = 50.0 bits (114), Expect = 5e-05
Identities = 24/56 (42%), Positives = 36/56 (64%), Gaps = 2/56 (3%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSAD--QCAQFHCTKMELEDIWPLADYIT 669
+GLGR+G ATR AFGMNI+ DPF+ AD Q + + T + L+D+ +D ++
Sbjct: 147 IGLGRIGSFTATRAKAFGMNILAADPFLKADAPQLKKLNATLLSLDDLLAESDVVS 202
>UniRef50_A4MA79 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Petrotoga mobilis
SJ95|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Petrotoga mobilis SJ95
Length = 310
Score = 73.7 bits (173), Expect = 4e-12
Identities = 34/77 (44%), Positives = 49/77 (63%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG G+DNIDVD+A KG+ V+N PG N+LS EL ++L + RH+ + LK +W+
Sbjct: 70 RAGMGLDNIDVDTAKLKGITVLNTPGQNSLSVAELVIGMVLDIYRHITRGTIGLKNEQWE 129
Query: 461 RALYTGSELAGKTLAIL 511
+ G EL+ KT I+
Sbjct: 130 KKQLEGFELSQKTFGII 146
Score = 36.3 bits (80), Expect = 0.67
Identities = 18/40 (45%), Positives = 26/40 (65%)
Frame = +3
Query: 153 TKAKISKEELLMEIPNHDALVVRSATQVTKEVLDQA*SLR 272
T + K+ L +I D L+VRSAT+VTKE+L+ A L+
Sbjct: 27 TSEHLEKDVLKDKIKEIDVLIVRSATKVTKEILEHADKLK 66
>UniRef50_Q97N23 Cluster: D-3-phosphoglycerate dehydrogenase; n=10;
Clostridiaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Clostridium acetobutylicum
Length = 305
Score = 73.3 bits (172), Expect = 5e-12
Identities = 33/77 (42%), Positives = 49/77 (63%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG GVDNIDV A KG+ V N P A++ S EL M ++R + A+ ++ G+W+
Sbjct: 73 RAGVGVDNIDVTYARDKGLTVNNTPNASSASVAELAIGHMFAVSRFINTANVTMRQGKWE 132
Query: 461 RALYTGSELAGKTLAIL 511
+ YTG+E+ GKTL ++
Sbjct: 133 KKAYTGTEIFGKTLGLI 149
Score = 42.3 bits (95), Expect = 0.010
Identities = 20/30 (66%), Positives = 25/30 (83%)
Frame = +3
Query: 171 KEELLMEIPNHDALVVRSATQVTKEVLDQA 260
K+ELL++I D LVVRSAT+VTKEV+D A
Sbjct: 32 KDELLVKIKEFDVLVVRSATKVTKEVIDAA 61
>UniRef50_Q7D366 Cluster: AGR_pAT_578p; n=2; Agrobacterium
tumefaciens str. C58|Rep: AGR_pAT_578p - Agrobacterium
tumefaciens (strain C58 / ATCC 33970)
Length = 317
Score = 72.5 bits (170), Expect = 8e-12
Identities = 36/83 (43%), Positives = 48/83 (57%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R G GVDNID+D+A + G+ V NAPG NA + ELT L+L R + AL+ G WD
Sbjct: 77 RFGVGVDNIDIDAAHRHGIAVTNAPGGNANAVAELTLGLILSAMRRIPYLHDALRGGAWD 136
Query: 461 RALYTGSELAGKTLAILALAGSA 529
R + G EL G+ + +L A
Sbjct: 137 R--FVGQELIGRRVGLLGFGNIA 157
>UniRef50_Q0EUV6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Thermoanaerobacter
ethanolicus|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Thermoanaerobacter
ethanolicus X514
Length = 320
Score = 72.5 bits (170), Expect = 8e-12
Identities = 36/79 (45%), Positives = 51/79 (64%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R G G DN+D+++A KKG+ V N P AN S +L LMLVLAR+++ +K+G W
Sbjct: 78 RYGVGYDNVDLNAAKKKGIVVTNTPNANNNSVADLVIGLMLVLARNLLAVDRIVKSGGWK 137
Query: 461 RALYTGSELAGKTLAILAL 517
R + G+E+ GKTL I+ L
Sbjct: 138 RIM--GTEIYGKTLGIIGL 154
Score = 35.1 bits (77), Expect = 1.5
Identities = 15/54 (27%), Positives = 29/54 (53%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+GLG++G+ VA R F MN++ +D + ++ T E++ +D +T
Sbjct: 152 IGLGKIGKGVAKRAKGFDMNVLCYDVYPDLKFSEEYGVTYCSFEELLKQSDIVT 205
>UniRef50_Q2LGV1 Cluster: Phosphoglycerate dehydrogenase; n=6;
Halobacteriaceae|Rep: Phosphoglycerate dehydrogenase -
Haloquadratum walsbyi
Length = 536
Score = 72.5 bits (170), Expect = 8e-12
Identities = 35/79 (44%), Positives = 48/79 (60%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG GVDNID+D+A + GV V NAP N +A E T + AR + A L+ G W
Sbjct: 73 RAGIGVDNIDIDAATEHGVIVANAPEGNVRAAAEHTVAMTFAGARSIPQAHARLRTGEWA 132
Query: 461 RALYTGSELAGKTLAILAL 517
++ Y G+E+ GKTL ++ L
Sbjct: 133 KSEYLGTEVNGKTLGVVGL 151
Score = 45.6 bits (103), Expect = 0.001
Identities = 18/54 (33%), Positives = 35/54 (64%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+GLGRVG+ VA R+ + GM+++ +DP++S D+ + +E + A+++T
Sbjct: 149 VGLGRVGQEVAKRLESLGMDLVAYDPYISEDRAERLGAELVEFDTCLERAEFLT 202
Score = 36.3 bits (80), Expect = 0.67
Identities = 23/59 (38%), Positives = 30/59 (50%)
Frame = +3
Query: 84 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDQA 260
VL+ D + E L A G + T I E LL I + +ALVVRS T V + V + A
Sbjct: 7 VLVTDPIDDAGLERLRAAGHSVETAYDIGDEALLNTITDVNALVVRSGTDVNEAVFEAA 65
>UniRef50_A0V9Y4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Comamonadaceae|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Delftia acidovorans SPH-1
Length = 354
Score = 71.3 bits (167), Expect = 2e-11
Identities = 37/83 (44%), Positives = 47/83 (56%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
G GV NIDV +A ++G+ V PGANA S E+T LM AR + L+AGRW RA
Sbjct: 102 GVGVSNIDVAAASQRGIPVYVTPGANAQSVAEMTLGLMFAAARRIAWMDAELRAGRWSRA 161
Query: 467 LYTGSELAGKTLAILALAGSADR 535
G EL+G+TL +L R
Sbjct: 162 -QDGLELSGRTLGLLGFGQVGQR 183
>UniRef50_UPI0000DC0E13 Cluster: 3-phosphoglycerate dehydrogenase;
n=4; Amniota|Rep: 3-phosphoglycerate dehydrogenase -
Rattus norvegicus
Length = 316
Score = 70.1 bits (164), Expect = 4e-11
Identities = 34/79 (43%), Positives = 51/79 (64%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG G+DN+++++A K + V+N P +LSA ELTC +++ L R + P G+WD
Sbjct: 69 RAGTGMDNVNLEAAMTKSILVMNTPNGKSLSASELTCGMIVCLTRQIPP-------GKWD 121
Query: 461 RALYTGSELAGKTLAILAL 517
+ + G+EL GKTL IL L
Sbjct: 122 QEEFMGTELNGKTLGILGL 140
Score = 63.7 bits (148), Expect = 4e-09
Identities = 28/54 (51%), Positives = 37/54 (68%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
LGLGR+GR V T+M AF M +GFDP S + A F ++ LE++WPL D+IT
Sbjct: 138 LGLGRIGREVTTQMQAFRMKAVGFDPISSPEIAASFGVQQLLLEELWPLCDFIT 191
Score = 33.5 bits (73), Expect = 4.7
Identities = 20/60 (33%), Positives = 31/60 (51%)
Frame = +3
Query: 72 DIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 251
++ VLI D + C +LL G+ K +SKEEL++EI + + V + T E L
Sbjct: 5 NLHKVLISDILDPGCWKLLKDGGLQVVEKQNLSKEELIVEIQDCETTKVTADVTNTAEKL 64
>UniRef50_Q8EMJ8 Cluster: Hypothetical conserved protein; n=1;
Oceanobacillus iheyensis|Rep: Hypothetical conserved
protein - Oceanobacillus iheyensis
Length = 319
Score = 70.1 bits (164), Expect = 4e-11
Identities = 37/78 (47%), Positives = 47/78 (60%), Gaps = 1/78 (1%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R G GVDNIDV +A K G+ V N P AN + EL T ML RH++P A++AG +D
Sbjct: 70 RHGIGVDNIDVKAATKYGIKVTNTPSANINAVAELVLTFMLASTRHLLPIDEAVRAGNFD 129
Query: 461 -RALYTGSELAGKTLAIL 511
R G EL GKT+ I+
Sbjct: 130 IRNQLFGYELNGKTVGII 147
Score = 40.7 bits (91), Expect = 0.031
Identities = 19/55 (34%), Positives = 32/55 (58%), Gaps = 1/55 (1%)
Frame = +1
Query: 508 LGLGRVGR*VATRM-YAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+G G +GR +A + GMNI+ FDP+V+A+ + LED+ ++D +T
Sbjct: 147 IGFGNIGRLIAEKCRLGLGMNIVVFDPYVTAESVEPYVELTESLEDLLRISDVVT 201
>UniRef50_A1IDH6 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Deltaproteobacteria|Rep: D-3-phosphoglycerate
dehydrogenase - Candidatus Desulfococcus oleovorans Hxd3
Length = 532
Score = 69.7 bits (163), Expect = 6e-11
Identities = 28/77 (36%), Positives = 49/77 (63%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG G+DN+D+ +A K GV V+N P N ++ E T +M+ L R++ + +L++G+W+
Sbjct: 73 RAGIGLDNVDIPAATKHGVAVMNTPEGNVVTTAEHTIAMMMALTRNIPQGTLSLRSGQWE 132
Query: 461 RALYTGSELAGKTLAIL 511
+ G E+ KTL ++
Sbjct: 133 KKKLQGREVFNKTLGVI 149
Score = 41.9 bits (94), Expect = 0.013
Identities = 23/58 (39%), Positives = 34/58 (58%), Gaps = 1/58 (1%)
Frame = +3
Query: 84 VLIVDGVGAK-CAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 254
VL+ D + A + L N G A K + EEL I +DAL++RSAT+VT ++L+
Sbjct: 5 VLVSDTIDASGVSRLENESGFAVDVKTGLPPEELKSIIGQYDALIIRSATKVTADILE 62
Score = 38.3 bits (85), Expect = 0.17
Identities = 19/54 (35%), Positives = 29/54 (53%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+G G++G VA R MN+I FDP ++ + L+D++ ADYIT
Sbjct: 149 IGFGKIGSIVADRARQLKMNVIVFDPNIARTTIENEGFEYVSLDDLFARADYIT 202
>UniRef50_Q8XPB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Clostridium perfringens|Rep: D-3-phosphoglycerate
dehydrogenase - Clostridium perfringens
Length = 301
Score = 68.9 bits (161), Expect = 1e-10
Identities = 34/79 (43%), Positives = 46/79 (58%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R G GVDNIDV A + G+ V N P A++ S E+ M LAR + ++ +KAG W
Sbjct: 72 RGGVGVDNIDVQYAEQNGIKVRNTPNASSSSVAEIILAHMFSLARFLNQSNITMKAGLWK 131
Query: 461 RALYTGSELAGKTLAILAL 517
+ Y G EL GKTL I+ +
Sbjct: 132 KKDYVGVELEGKTLGIIGM 150
Score = 35.1 bits (77), Expect = 1.5
Identities = 19/59 (32%), Positives = 32/59 (54%)
Frame = +3
Query: 84 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDQA 260
+L+ DG+ K L G T E+L +I D +V+RSAT++ +E++D+A
Sbjct: 4 ILLNDGLDKKAISNLEFLGFDVDTN-HYDIEDLKEKIKKVDCIVIRSATKIRRELIDEA 61
>UniRef50_A4YUP8 Cluster: Putative D-3-phosphoglycerate
dehydrogenase; n=1; Bradyrhizobium sp. ORS278|Rep:
Putative D-3-phosphoglycerate dehydrogenase -
Bradyrhizobium sp. (strain ORS278)
Length = 335
Score = 68.9 bits (161), Expect = 1e-10
Identities = 30/75 (40%), Positives = 46/75 (61%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
G G DNIDV++A ++G+ V A GAN+ S EL LM +AR + +K G WD+A
Sbjct: 85 GVGYDNIDVEAADRRGIPVFVARGANSQSVAELAFALMFAVAREIPHLDARIKTGHWDKA 144
Query: 467 LYTGSELAGKTLAIL 511
G++L G++L ++
Sbjct: 145 TTKGAQLLGRSLGVI 159
>UniRef50_Q9RUU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Deinococci|Rep: D-3-phosphoglycerate dehydrogenase -
Deinococcus radiodurans
Length = 544
Score = 68.5 bits (160), Expect = 1e-10
Identities = 34/79 (43%), Positives = 49/79 (62%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R G GVDNID++ A ++G+ V+NAP +N +SA EL ++ AR + + +AG WD
Sbjct: 86 RGGVGVDNIDLEYASRRGLLVLNAPESNNVSAAELAVMHLMAAARGLTRSDRKTRAGEWD 145
Query: 461 RALYTGSELAGKTLAILAL 517
R + G EL KTL I+ L
Sbjct: 146 RK-FLGLELTDKTLGIVGL 163
Score = 38.7 bits (86), Expect = 0.13
Identities = 17/45 (37%), Positives = 28/45 (62%)
Frame = +3
Query: 126 LNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDQA 260
L+ G + + +EE L +P++DAL+ RS T+V +E+LD A
Sbjct: 33 LDHEGFQIDYQGNLEREETLRRLPDYDALITRSRTKVDRELLDAA 77
Score = 33.9 bits (74), Expect = 3.6
Identities = 13/28 (46%), Positives = 19/28 (67%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFV 591
+GLGR+G VA R MN++ +DP+V
Sbjct: 161 VGLGRIGSIVADRAQGLHMNVVAYDPYV 188
>UniRef50_UPI00015BAF48 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Ignicoccus hospitalis
KIN4/I|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Ignicoccus hospitalis
KIN4/I
Length = 308
Score = 68.1 bits (159), Expect = 2e-10
Identities = 34/77 (44%), Positives = 51/77 (66%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG+G+DNID+++A +KG+ V+NAP A + EL +M+VLAR + L G W+
Sbjct: 71 RAGSGLDNIDLEAAKEKGIKVVNAPDALKNAVAELVIGMMVVLARRAHYSYRKLLEGEWE 130
Query: 461 RALYTGSELAGKTLAIL 511
+ + G ELAGKTL ++
Sbjct: 131 KVM--GFELAGKTLGVV 145
Score = 32.7 bits (71), Expect = 8.2
Identities = 13/25 (52%), Positives = 18/25 (72%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFD 582
+G GR+GR VA + A GMN+I +D
Sbjct: 145 VGFGRIGREVAKKAKALGMNVIAYD 169
>UniRef50_Q4WHR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Aspergillus fumigatus|Rep: D-3-phosphoglycerate
dehydrogenase - Aspergillus fumigatus (Sartorya
fumigata)
Length = 635
Score = 68.1 bits (159), Expect = 2e-10
Identities = 29/70 (41%), Positives = 49/70 (70%)
Frame = +2
Query: 308 DVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSEL 487
DV+ A K G+ V+N+P N +A E T L++ +AR++ A ++LK+G+W+R+ + G E+
Sbjct: 109 DVEEATKLGIVVVNSPSGNIGAAAEHTIALLMAMARNIPEACSSLKSGKWERSKFVGVEV 168
Query: 488 AGKTLAILAL 517
GKTL+I+ L
Sbjct: 169 KGKTLSIIGL 178
Score = 34.7 bits (76), Expect = 2.0
Identities = 22/63 (34%), Positives = 34/63 (53%)
Frame = +3
Query: 84 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDQA* 263
VL+ + + LL A + + + +ELL IP ++ALVVRS T+VT +L A
Sbjct: 11 VLVPEKLSPDGLALLRA-SLEVDERRGLDADELLQIIPEYEALVVRSETKVTANLLRAAK 69
Query: 264 SLR 272
L+
Sbjct: 70 QLK 72
>UniRef50_A4FHH0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
D-3-phosphoglycerate dehydrogenase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 336
Score = 67.3 bits (157), Expect = 3e-10
Identities = 33/80 (41%), Positives = 49/80 (61%), Gaps = 1/80 (1%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG+G + ID +SA ++GV V N PG NA++ EL LML L R V L+AGRWD
Sbjct: 68 RAGSGTNTIDCESAAERGVHVCNVPGRNAIAVAELAFALMLALDRSVCDNVDDLRAGRWD 127
Query: 461 RALYTGSE-LAGKTLAILAL 517
+ Y+ + + G+ + ++ L
Sbjct: 128 KKRYSRARGIHGRRVGVVGL 147
>UniRef50_Q0J5C2 Cluster: Os08g0447000 protein; n=11;
Viridiplantae|Rep: Os08g0447000 protein - Oryza sativa
subsp. japonica (Rice)
Length = 666
Score = 67.3 bits (157), Expect = 3e-10
Identities = 37/89 (41%), Positives = 51/89 (57%), Gaps = 12/89 (13%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA---- 448
RAG G+DN+D+ +A + G V+NAP AN ++A E L+ +AR+V A ALKA
Sbjct: 146 RAGVGIDNVDLQAATEAGCLVVNAPTANTVAAAEHGIALLASMARNVSQADAALKAVYSR 205
Query: 449 --------GRWDRALYTGSELAGKTLAIL 511
G+W R Y G L GKTLA++
Sbjct: 206 TLTVFTAQGKWQRTKYVGVSLVGKTLAVM 234
Score = 37.1 bits (82), Expect = 0.38
Identities = 17/54 (31%), Positives = 28/54 (51%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+G G+VG VA R GM++I DP+ AD+ + ++ AD+I+
Sbjct: 234 MGFGKVGSEVARRAKGLGMHVIAHDPYAPADRARAIGAELVSFDEAIGRADFIS 287
Score = 35.9 bits (79), Expect = 0.88
Identities = 16/30 (53%), Positives = 23/30 (76%)
Frame = +3
Query: 165 ISKEELLMEIPNHDALVVRSATQVTKEVLD 254
+S ELL ++ DAL+VRS T+VT+EVL+
Sbjct: 106 MSPAELLAKVAQFDALIVRSGTKVTREVLE 135
>UniRef50_A7HEG1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=4; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase NAD-binding -
Anaeromyxobacter sp. Fw109-5
Length = 399
Score = 66.9 bits (156), Expect = 4e-10
Identities = 35/86 (40%), Positives = 54/86 (62%), Gaps = 1/86 (1%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAGAGV+ IDV +A ++GV V N PG N+++ EL L++ L R + L+AG+WD
Sbjct: 68 RAGAGVNTIDVAAASRRGVYVANCPGQNSIAVAELAIGLVVALDRRIPDNVALLRAGKWD 127
Query: 461 RALYTGSE-LAGKTLAILALAGSADR 535
+ ++ ++ L G+TL + A GS R
Sbjct: 128 KKTFSEAQGLYGRTLGV-AGVGSIGR 152
>UniRef50_UPI0000E4762C Cluster: PREDICTED: similar to
D-3-phosphoglycerate dehydrogenase; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
D-3-phosphoglycerate dehydrogenase - Strongylocentrotus
purpuratus
Length = 493
Score = 66.5 bits (155), Expect = 5e-10
Identities = 29/54 (53%), Positives = 37/54 (68%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+GLGR+GR VA RM +FGM IGFDP V A++ Q++ LE +WP DYIT
Sbjct: 114 VGLGRIGREVAQRMQSFGMTTIGFDPIVPAEEAKQYNIEWQTLEQMWPRCDYIT 167
Score = 64.9 bits (151), Expect = 2e-09
Identities = 33/71 (46%), Positives = 41/71 (57%)
Frame = +2
Query: 305 IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSE 484
IDV + G PG N LSA E TC ++ L+R + A LKAG+WDR + GSE
Sbjct: 46 IDVYDYLRMAWGSTYTPGGNTLSAAEHTCAMVCCLSRSLPQAHATLKAGKWDRKAFMGSE 105
Query: 485 LAGKTLAILAL 517
L GKTL I+ L
Sbjct: 106 LYGKTLGIVGL 116
Score = 48.4 bits (110), Expect = 2e-04
Identities = 23/45 (51%), Positives = 27/45 (60%)
Frame = +3
Query: 63 MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIP 197
M +K VLI D V +CAE+L GI K+SKEELL EIP
Sbjct: 1 MAFSLKKVLISDSVSPRCAEILRENGIEVDNNTKLSKEELLAEIP 45
>UniRef50_Q0FX01 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding subunit; n=3;
Rhodobacteraceae|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding subunit - Roseovarius sp.
HTCC2601
Length = 326
Score = 66.5 bits (155), Expect = 5e-10
Identities = 34/83 (40%), Positives = 47/83 (56%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
G GVDNID+ + + G+ V N P ANA + EL LM +AR + ++ AG WDR
Sbjct: 80 GVGVDNIDIPACTEAGLPVCNTPAANADAVAELAVGLMFSMARWIPQGHASVTAGGWDRR 139
Query: 467 LYTGSELAGKTLAILALAGSADR 535
+ G++L GKTL I+ L R
Sbjct: 140 I--GTQLGGKTLGIVGLGNIGKR 160
>UniRef50_A1AR04 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Pelobacter propionicus
DSM 2379|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Pelobacter propionicus
(strain DSM 2379)
Length = 357
Score = 66.5 bits (155), Expect = 5e-10
Identities = 28/82 (34%), Positives = 52/82 (63%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG+G+DN+DV+ A K+GV ++ P +A + E+ ML L+R ++ A +++ GRW+
Sbjct: 91 RAGSGMDNLDVEYARKRGVQLVRIPQPSARAVAEMAFAFMLALSRRLLEADRSMRNGRWE 150
Query: 461 RALYTGSELAGKTLAILALAGS 526
+ ++G L KTL ++ + +
Sbjct: 151 KHEFSGYLLRDKTLGVVGIGNT 172
>UniRef50_A0JVX0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Arthrobacter sp.
FB24|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Arthrobacter sp. (strain FB24)
Length = 319
Score = 66.5 bits (155), Expect = 5e-10
Identities = 32/77 (41%), Positives = 50/77 (64%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R G GVD+IDV++A + G+ V+ APGAN+ ELT L+L +R + LK+G+W+
Sbjct: 89 RNGVGVDSIDVEAAERLGINVLTAPGANSQGVAELTIALILAGSRSIPWHDAQLKSGQWN 148
Query: 461 RALYTGSELAGKTLAIL 511
R G+E++GK L ++
Sbjct: 149 RR--PGNEVSGKVLGLI 163
>UniRef50_O50096 Cluster: Putative uncharacterized protein PH1388;
n=1; Pyrococcus horikoshii|Rep: Putative uncharacterized
protein PH1388 - Pyrococcus horikoshii
Length = 119
Score = 66.5 bits (155), Expect = 5e-10
Identities = 38/79 (48%), Positives = 45/79 (56%)
Frame = -1
Query: 498 VLPASSLPVYRARSHLPAFSAVEAGTTWRARTNINVQVSSHALSALAPGALITPTPFLPA 319
VLP+SS+P+ +H P+ + A + A NIN SS L LA GAL T PF A
Sbjct: 5 VLPSSSIPIASFFAHTPSLIFLSAKAIFLATENINPTASSATLLELAAGALTTSIPFSLA 64
Query: 318 ESTSMLSTPAPARPTTLSF 262
STSMLS P PA TLSF
Sbjct: 65 ASTSMLSKPTPALAITLSF 83
>UniRef50_A6ULR7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Sinorhizobium medicae
WSM419|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding - Sinorhizobium medicae WSM419
Length = 328
Score = 66.1 bits (154), Expect = 7e-10
Identities = 33/85 (38%), Positives = 50/85 (58%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R G G +N+D++SA ++GV V+ A GAN S EL L L +AR + +++A +W+
Sbjct: 73 RHGVGYNNVDIESATRRGVPVLIADGANGKSVAELAVGLALSVARKITTQDASIRARQWN 132
Query: 461 RALYTGSELAGKTLAILALAGSADR 535
R+ Y G + AGKT I+A R
Sbjct: 133 RSAY-GLQFAGKTAGIVAFGAIGRR 156
>UniRef50_A5URV2 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Roseiflexus sp.
RS-1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Roseiflexus sp. RS-1
Length = 323
Score = 65.3 bits (152), Expect = 1e-09
Identities = 34/79 (43%), Positives = 44/79 (55%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R G GVDNID+ +A K+G+ VIN P S E L+L LA+ VV + L+ W
Sbjct: 74 RPGIGVDNIDIAAATKRGILVINTPDGPTESTAEHAVALLLALAKQVVASDRVLRTEGWR 133
Query: 461 RALYTGSELAGKTLAILAL 517
A G E+ GKTL I+ L
Sbjct: 134 AARLRGIEVRGKTLGIVGL 152
>UniRef50_Q18XF4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Desulfitobacterium
hafniense|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Desulfitobacterium
hafniense (strain DCB-2)
Length = 320
Score = 64.9 bits (151), Expect = 2e-09
Identities = 33/77 (42%), Positives = 45/77 (58%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
G GVD+ID+ +A +G+ V NAPG NA S +L ML LAR +V A + G W
Sbjct: 80 GTGVDSIDLKAAAARGITVANAPGTNANSVADLAFGFMLSLARQIVSADKRTRDGFWGTV 139
Query: 467 LYTGSELAGKTLAILAL 517
+ G ++ GKTL +L L
Sbjct: 140 M--GKDVYGKTLGVLGL 154
Score = 38.7 bits (86), Expect = 0.13
Identities = 20/54 (37%), Positives = 30/54 (55%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
LGLG++G+ V R F MNI+G+D + ++ LE+I ADYI+
Sbjct: 152 LGLGQIGKGVIRRASGFDMNILGYDLVHHSQFEKEYRVRAATLEEIMSEADYIS 205
>UniRef50_A4ETV8 Cluster: Putative uncharacterized protein; n=6;
Alphaproteobacteria|Rep: Putative uncharacterized
protein - Roseobacter sp. SK209-2-6
Length = 166
Score = 64.9 bits (151), Expect = 2e-09
Identities = 38/78 (48%), Positives = 42/78 (53%)
Frame = -1
Query: 501 RVLPASSLPVYRARSHLPAFSAVEAGTTWRARTNINVQVSSHALSALAPGALITPTPFLP 322
RVL SS+P+ SHLPA+ EA WRA NI S + L G IT TP L
Sbjct: 8 RVLLVSSVPMNLDFSHLPAWVEAEASGIWRATANIIAMACSAVVIILPNGVFITITPRLE 67
Query: 321 AESTSMLSTPAPARPTTL 268
A S SMLS P PAR TL
Sbjct: 68 AASLSMLSVPMPARAMTL 85
>UniRef50_A6Q7Q2 Cluster: D-3-phosphoglycerate dehydrogenase; n=27;
Epsilonproteobacteria|Rep: D-3-phosphoglycerate
dehydrogenase - Sulfurovum sp. (strain NBC37-1)
Length = 529
Score = 64.5 bits (150), Expect = 2e-09
Identities = 35/86 (40%), Positives = 46/86 (53%), Gaps = 1/86 (1%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR-W 457
RAG GVDN+D+ + K+G+ V+N P AN ++A ELT ML R A LK R W
Sbjct: 74 RAGVGVDNVDIPGSSKQGIVVMNVPTANTIAAVELTLAHMLSCVRQFPYAHNNLKLDRVW 133
Query: 458 DRALYTGSELAGKTLAILALAGSADR 535
R + G+EL K L I+ R
Sbjct: 134 RRQDWYGTELKDKKLGIIGFGNIGSR 159
>UniRef50_UPI000050F9E4 Cluster: COG0111: Phosphoglycerate
dehydrogenase and related dehydrogenases; n=1;
Brevibacterium linens BL2|Rep: COG0111: Phosphoglycerate
dehydrogenase and related dehydrogenases -
Brevibacterium linens BL2
Length = 314
Score = 64.1 bits (149), Expect = 3e-09
Identities = 32/82 (39%), Positives = 44/82 (53%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG G DN+D+D+A + G+ V N PG N + EL LML AR + + G W
Sbjct: 76 RAGVGYDNVDIDAAAELGIRVCNTPGVNHHAVAELALALMLACARRLNTVLAGVDDGGWP 135
Query: 461 RALYTGSELAGKTLAILALAGS 526
R G+EL GK+L ++ S
Sbjct: 136 RE--AGTELRGKSLGVIGYGPS 155
>UniRef50_Q6W1I8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Rhizobium sp. NGR234|Rep: D-3-phosphoglycerate
dehydrogenase - Rhizobium sp. (strain NGR234)
Length = 327
Score = 63.7 bits (148), Expect = 4e-09
Identities = 34/78 (43%), Positives = 47/78 (60%), Gaps = 1/78 (1%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R G G D+ID D+A + GVG+ PG NA + + T ++L L R VV A+KAGRWD
Sbjct: 76 RVGVGTDSIDHDAAKEFGVGISVTPGMNAETVADQTLAMILGLMRRVVTQDQAVKAGRWD 135
Query: 461 R-ALYTGSELAGKTLAIL 511
R T +EL KT+ ++
Sbjct: 136 RVGEATPTELYRKTVGLI 153
>UniRef50_A6UCB8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=2; Sinorhizobium|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Sinorhizobium medicae WSM419
Length = 310
Score = 63.7 bits (148), Expect = 4e-09
Identities = 33/86 (38%), Positives = 51/86 (59%), Gaps = 1/86 (1%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA-LKAGRW 457
R G G+DN+ + ++G+G++ A GANA+ EL+ LML RH +PA TA ++AG W
Sbjct: 76 RNGTGIDNLPLPLLKERGIGILKAEGANAVGVAELSVGLMLAALRH-IPAETAGIRAGGW 134
Query: 458 DRALYTGSELAGKTLAILALAGSADR 535
R+ G E+A +T+ I+ R
Sbjct: 135 PRS--RGREIAERTVGIIGCGAIGKR 158
>UniRef50_A6DQ00 Cluster: SerA; n=1; Lentisphaera araneosa
HTCC2155|Rep: SerA - Lentisphaera araneosa HTCC2155
Length = 522
Score = 63.3 bits (147), Expect = 5e-09
Identities = 30/76 (39%), Positives = 43/76 (56%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAGAG + ID+ A K + V+N PGAN+ + E +M+ AR + + +AG W
Sbjct: 70 RAGAGYNTIDIQYARSKDITVMNTPGANSNAVAEEAVGMMISCARFFIEGDRSTRAGEWK 129
Query: 461 RALYTGSELAGKTLAI 508
+A G EL GKT+ I
Sbjct: 130 KAQLQGFELTGKTVGI 145
Score = 46.4 bits (105), Expect = 6e-04
Identities = 19/53 (35%), Positives = 36/53 (67%)
Frame = +1
Query: 511 GLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
G G +G+ +A R+ F ++I+ +DPFVS D+ A+F + LE+++ +D+I+
Sbjct: 147 GFGNIGQLLAKRLSGFEVDILVYDPFVSEDKLAEFGAKNVSLEELFAGSDFIS 199
>UniRef50_A1RDF9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=1; Arthrobacter
aurescens TC1|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Arthrobacter aurescens
(strain TC1)
Length = 329
Score = 62.9 bits (146), Expect = 7e-09
Identities = 31/87 (35%), Positives = 48/87 (55%), Gaps = 2/87 (2%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW- 457
R G G DN+D+ +A + V V + PG+N+ + E +L+L L R ++PA+ + AG W
Sbjct: 68 RHGVGTDNVDIPAASEHSVWVTSTPGSNSNAVAEHVFSLLLSLTRRIIPAANRVLAGTWA 127
Query: 458 -DRALYTGSELAGKTLAILALAGSADR 535
R G EL+G+TL I+ R
Sbjct: 128 EGRGDLVGFELSGRTLGIVGFGAIGKR 154
Score = 37.1 bits (82), Expect = 0.38
Identities = 18/54 (33%), Positives = 28/54 (51%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+G G +G+ VAT FGM ++ DP +A +EL+ ++ AD IT
Sbjct: 146 VGFGAIGKRVATIANGFGMRVLASDPIATAADAEAAGAVLVELDTLYDGADIIT 199
>UniRef50_A1HSQ7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Thermosinus
carboxydivorans Nor1|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Thermosinus
carboxydivorans Nor1
Length = 317
Score = 62.9 bits (146), Expect = 7e-09
Identities = 33/77 (42%), Positives = 43/77 (55%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
G G + IDV +A G+ V PGAN +S EL LML +ARH+ ++ G W R
Sbjct: 78 GVGYNTIDVAAAAAYGIPVTITPGANNISVAELAIGLMLAVARHIPQMDGIVRRGGWSR- 136
Query: 467 LYTGSELAGKTLAILAL 517
TGSEL GK L I+ +
Sbjct: 137 -MTGSELYGKVLGIIGM 152
Score = 37.5 bits (83), Expect = 0.29
Identities = 18/54 (33%), Positives = 29/54 (53%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+G+G +G VA R +AFGM II +D D + T + + D AD+++
Sbjct: 150 IGMGSIGCEVAKRAHAFGMKIIAYDIRPRQDMIENYGVTYLPMADCLAQADFLS 203
>UniRef50_A7NGZ0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Roseiflexus castenholzii
DSM 13941|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding - Roseiflexus castenholzii DSM
13941
Length = 345
Score = 62.5 bits (145), Expect = 9e-09
Identities = 32/79 (40%), Positives = 43/79 (54%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R G GVDNID+ +A ++G+ VIN P S E L+L LA+ VV A + W
Sbjct: 75 RPGIGVDNIDLAAATERGILVINTPDGPTESTAEHAVALVLALAKQVVAADHRFRTAGWS 134
Query: 461 RALYTGSELAGKTLAILAL 517
A G E+ GKTL ++ L
Sbjct: 135 AARLRGVEVRGKTLGVVGL 153
>UniRef50_Q97ZK1 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Sulfolobaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Sulfolobus solfataricus
Length = 326
Score = 62.5 bits (145), Expect = 9e-09
Identities = 32/77 (41%), Positives = 47/77 (61%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG G+DNID + A K+ + ++ APGA+ SA ELT L++ AR + + K G +
Sbjct: 86 RAGIGLDNIDTEEASKRNIKIVYAPGASTDSAAELTIGLLIAAARKLYDSMNMAKGGIFK 145
Query: 461 RALYTGSELAGKTLAIL 511
+ G ELAGKT+ I+
Sbjct: 146 K--IEGIELAGKTIGIV 160
Score = 41.1 bits (92), Expect = 0.024
Identities = 24/61 (39%), Positives = 34/61 (55%)
Frame = +3
Query: 69 VDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEV 248
+D K VLI D V L G+ K +I++EELL I + L+VRS T+V KE+
Sbjct: 16 LDFK-VLITDPVDQYMIRTLQNNGLIVDYKPEITREELLKIIDQYQVLIVRSRTKVDKEI 74
Query: 249 L 251
+
Sbjct: 75 I 75
>UniRef50_Q6MN05 Cluster: Phosphoglycerate dehydrogenase; n=1;
Bdellovibrio bacteriovorus|Rep: Phosphoglycerate
dehydrogenase - Bdellovibrio bacteriovorus
Length = 328
Score = 61.3 bits (142), Expect = 2e-08
Identities = 32/82 (39%), Positives = 47/82 (57%)
Frame = +2
Query: 290 AGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL 469
+G D+ID+++ K GV V++ P AN SA +LT L+L ++ A +KAG W+R
Sbjct: 74 SGFDHIDLEATQKWGVTVMHTPTANIESAAQLTWGLVLSCVNNIQAAHKMVKAGEWNRDQ 133
Query: 470 YTGSELAGKTLAILALAGSADR 535
TG ELAG+ I+ L R
Sbjct: 134 ITGIELAGRNYGIVGLGRIGSR 155
Score = 46.0 bits (104), Expect = 8e-04
Identities = 19/54 (35%), Positives = 32/54 (59%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+GLGR+G VA AFGMN++ +DP+ + + H ++ E++ AD I+
Sbjct: 147 VGLGRIGSRVAELAQAFGMNVVAYDPYQEDEVFERLHIPRLSYEEVLKTADVIS 200
>UniRef50_Q39LG4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=2; Burkholderia|Rep: D-isomer specific
2-hydroxyacid dehydrogenase - Burkholderia sp. (strain
383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
/ R18194))
Length = 312
Score = 61.3 bits (142), Expect = 2e-08
Identities = 27/77 (35%), Positives = 45/77 (58%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
GAG +N+DV +A ++G+ V +APG NA + + ++L LAR P + A++AGRW +
Sbjct: 73 GAGYENVDVAAAARRGIVVAHAPGTNASTVADHAIGMLLALARGYAPLTGAVRAGRWHAS 132
Query: 467 LYTGSELAGKTLAILAL 517
L G L ++ +
Sbjct: 133 RAARPTLTGAALGVIGM 149
>UniRef50_A0UAW1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=14; Burkholderiales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Burkholderia multivorans ATCC 17616
Length = 452
Score = 61.3 bits (142), Expect = 2e-08
Identities = 30/83 (36%), Positives = 45/83 (54%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
G+G+D ID D+A +G+ V A GANA + E L+L A+ V ++ G WD+A
Sbjct: 216 GSGIDVIDQDAAAARGIAVRAAVGANAAAVAEHAWALILACAKSVPQLDMRMREGHWDKA 275
Query: 467 LYTGSELAGKTLAILALAGSADR 535
+ EL G+TL ++ L R
Sbjct: 276 THKSVELDGRTLGLVGLGAIGRR 298
Score = 35.9 bits (79), Expect = 0.88
Identities = 21/46 (45%), Positives = 26/46 (56%), Gaps = 7/46 (15%)
Frame = +1
Query: 472 HWQRARWQ----DPRHLGL---GRVGR*VATRMYAFGMNIIGFDPF 588
HW +A + D R LGL G +GR VA AFGM ++ FDPF
Sbjct: 271 HWDKATHKSVELDGRTLGLVGLGAIGRRVAAIGVAFGMKVLAFDPF 316
>UniRef50_A0RW58 Cluster: Phosphoglycerate dehydrogenase; n=3;
Crenarchaeota|Rep: Phosphoglycerate dehydrogenase -
Cenarchaeum symbiosum
Length = 310
Score = 61.3 bits (142), Expect = 2e-08
Identities = 32/85 (37%), Positives = 45/85 (52%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R G G+DNID+ +A GV VINA + EL +ML +AR + A ++ G+W
Sbjct: 73 RVGVGLDNIDLAAAESAGVRVINAVEGATTAVSELVLGMMLCMARQIPRADRGIRGGKWL 132
Query: 461 RALYTGSELAGKTLAILALAGSADR 535
+ G+EL GK L I+ L R
Sbjct: 133 KGELGGTELKGKYLGIVGLGNIGRR 157
Score = 41.5 bits (93), Expect = 0.018
Identities = 20/61 (32%), Positives = 33/61 (54%)
Frame = +3
Query: 78 KSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDQ 257
++VLI D +L G+ + K +I+ EEL E P + ++VRS T +T E++
Sbjct: 5 ETVLICDKADPVLGRILQQNGLRVSYKPEITPEELAAEAPGYSIIIVRSRTTITGEIIRS 64
Query: 258 A 260
A
Sbjct: 65 A 65
>UniRef50_Q9WYG2 Cluster: Phosphoglycerate dehydrogenase, putative;
n=2; Thermotoga|Rep: Phosphoglycerate dehydrogenase,
putative - Thermotoga maritima
Length = 327
Score = 60.9 bits (141), Expect = 3e-08
Identities = 36/84 (42%), Positives = 50/84 (59%), Gaps = 1/84 (1%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL-KAGRWDR 463
G GVDNID+++A KKG+ V GAN+LS ELT + L+R +V A L RW+
Sbjct: 70 GVGVDNIDLEAATKKGIPVTITAGANSLSVAELTIAFIFALSRGLVWAHNKLFLERRWEG 129
Query: 464 ALYTGSELAGKTLAILALAGSADR 535
+ G E++GKTL ++ GS R
Sbjct: 130 TV--GQEVSGKTLGVVGF-GSIGR 150
Score = 39.1 bits (87), Expect = 0.095
Identities = 17/55 (30%), Positives = 31/55 (56%), Gaps = 1/55 (1%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKM-ELEDIWPLADYIT 669
+G G +GR V + GMN++ +DP+VS D T + +LE + +D+++
Sbjct: 143 VGFGSIGREVVKKAVCLGMNVLVYDPYVSKDSVRLLEATPVDDLEQLLKESDFVS 197
>UniRef50_Q0ETU3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Thermoanaerobacter
ethanolicus X514|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Thermoanaerobacter
ethanolicus X514
Length = 324
Score = 60.9 bits (141), Expect = 3e-08
Identities = 32/80 (40%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R GAGVDNIDV++A +KG+ V N P N LS E T ++L L++ + A+++G W
Sbjct: 69 RTGAGVDNIDVNAATEKGILVCNLPAVNNLSVAEHTIAMILNLSKQLSLMDKAVRSGNWG 128
Query: 461 -RALYTGSELAGKTLAILAL 517
R E+ GK L I+ +
Sbjct: 129 ARNSNISVEIEGKVLGIVGM 148
>UniRef50_Q5WLJ2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Bacillus|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus clausii (strain KSM-K16)
Length = 316
Score = 60.5 bits (140), Expect = 4e-08
Identities = 32/77 (41%), Positives = 47/77 (61%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
G GVDNIDVD+A K GV V N P AN + + +L+L LAR + + K G+W +
Sbjct: 75 GVGVDNIDVDAAKKHGVTVTNVPNANKHAVADFAFSLLLSLARQIPTGNEKTKKGKWP-S 133
Query: 467 LYTGSELAGKTLAILAL 517
L+ G+++ +TL I+ L
Sbjct: 134 LF-GADVYQQTLGIIGL 149
Score = 36.3 bits (80), Expect = 0.67
Identities = 14/54 (25%), Positives = 29/54 (53%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+GLG +G+ VA R F M ++ +DP++ + + L+ + +D++T
Sbjct: 147 IGLGAIGKEVARRASGFSMTVLAYDPYIDRTYARKNGIEAVSLDALLQQSDFVT 200
>UniRef50_Q46VE6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=6;
Proteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Ralstonia
eutropha (strain JMP134) (Alcaligenes eutrophus)
Length = 312
Score = 60.1 bits (139), Expect = 5e-08
Identities = 33/78 (42%), Positives = 42/78 (53%), Gaps = 1/78 (1%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R G G+DNIDV + +G+ VI A GANA S E T +L R S + G+W
Sbjct: 72 RLGVGLDNIDVAACRDRGIRVIPASGANARSVAEYVVTTAALLLRGAYLGSAEVAGGKWP 131
Query: 461 RA-LYTGSELAGKTLAIL 511
RA L G E GKTL ++
Sbjct: 132 RARLSEGREALGKTLGLI 149
>UniRef50_A4WXD4 Cluster: Dimethylmenaquinone methyltransferase;
n=1; Rhodobacter sphaeroides ATCC 17025|Rep:
Dimethylmenaquinone methyltransferase - Rhodobacter
sphaeroides ATCC 17025
Length = 334
Score = 60.1 bits (139), Expect = 5e-08
Identities = 25/79 (31%), Positives = 44/79 (55%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
G GVDNID+ +A +G+ V+ + G+N+ + E L L+L + + P + A+K G W +
Sbjct: 85 GVGVDNIDLAAAEARGIPVLRSMGSNSRAVAEHAIALALMLVKEIQPLNAAVKGGAWPKP 144
Query: 467 LYTGSELAGKTLAILALAG 523
+ G + G L ++ G
Sbjct: 145 TFIGKDFQGAMLGLVGYGG 163
>UniRef50_Q88ZU6 Cluster: Phosphoglycerate dehydrogenase; n=2;
Lactobacillus|Rep: Phosphoglycerate dehydrogenase -
Lactobacillus plantarum
Length = 392
Score = 59.7 bits (138), Expect = 6e-08
Identities = 33/88 (37%), Positives = 50/88 (56%), Gaps = 9/88 (10%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST-------- 436
RAGAGV+NI +D A G V N PG+NA + EL L+++ +R+++ A+T
Sbjct: 54 RAGAGVNNIPIDQATANGTAVFNTPGSNANAVKELIIGLLIMASRNLIAATTYSAQHTEA 113
Query: 437 -ALKAGRWDRALYTGSELAGKTLAILAL 517
+ D+ + G EL GKTLA++ L
Sbjct: 114 DISQRTEHDKTQFNGIELTGKTLAVIGL 141
Score = 41.5 bits (93), Expect = 0.018
Identities = 17/31 (54%), Positives = 23/31 (74%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSAD 600
+GLG VG VA + GMN+IG+DP++SAD
Sbjct: 139 IGLGHVGALVANAALSLGMNVIGYDPYLSAD 169
>UniRef50_Q03WU1 Cluster: Lactate dehydrogenase related
dehydrogenase; n=1; Leuconostoc mesenteroides subsp.
mesenteroides ATCC 8293|Rep: Lactate dehydrogenase
related dehydrogenase - Leuconostoc mesenteroides subsp.
mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 312
Score = 59.7 bits (138), Expect = 6e-08
Identities = 33/79 (41%), Positives = 46/79 (58%), Gaps = 2/79 (2%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR-- 454
R G G DNI V+SA K GV V N PGANA++ EL TL+L + R V A+ +++ G
Sbjct: 71 RRGVGYDNIPVESATKHGVWVTNTPGANAIAVAELAVTLILTVLRKVNQATNSVQKGEAL 130
Query: 455 WDRALYTGSELAGKTLAIL 511
A G L+GK + ++
Sbjct: 131 TYPASLMGHNLSGKIIGLI 149
>UniRef50_A3PPC6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Rhodobacteraceae|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Rhodobacter sphaeroides (strain ATCC 17029
/ ATH 2.4.9)
Length = 331
Score = 59.3 bits (137), Expect = 8e-08
Identities = 34/81 (41%), Positives = 45/81 (55%), Gaps = 1/81 (1%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-R 463
GAG D +D ++A +KGV V N PGANA S EL L L +AR + A AL+ G+ R
Sbjct: 70 GAGHDPVDKEAAARKGVVVANTPGANARSVAELAVGLALAVARRIPAADRALREGKTGFR 129
Query: 464 ALYTGSELAGKTLAILALAGS 526
SEL G+T ++ S
Sbjct: 130 ESARFSELRGRTALVVGWGAS 150
>UniRef50_Q3KBX8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Pseudomonas|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Pseudomonas fluorescens (strain PfO-1)
Length = 324
Score = 58.8 bits (136), Expect = 1e-07
Identities = 33/79 (41%), Positives = 44/79 (55%), Gaps = 2/79 (2%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW- 457
R GAG DN+D +A + GV V N PGAN S E L+L ++R V A+ + W
Sbjct: 68 RHGAGYDNVDYKAAAELGVWVTNTPGANRRSVVEHVFALLLGISRKVQLATDQTRNNIWA 127
Query: 458 -DRALYTGSELAGKTLAIL 511
DR TG EL G+TL ++
Sbjct: 128 QDRLSLTGIELEGRTLGLI 146
>UniRef50_A6PPS4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Victivallis vadensis
ATCC BAA-548|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Victivallis vadensis ATCC
BAA-548
Length = 316
Score = 58.8 bits (136), Expect = 1e-07
Identities = 32/85 (37%), Positives = 44/85 (51%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R G G DNI++ A +KG+ N PGA S E ++L+ AR + A+ + G W
Sbjct: 71 RFGIGCDNINLPRAAEKGIYCTNTPGALEQSVAECAIGMILLAARQFIAAADDCRNGLWQ 130
Query: 461 RALYTGSELAGKTLAILALAGSADR 535
TG ELAGKTLA++ R
Sbjct: 131 P--QTGCELAGKTLAVIGCGAIGSR 153
>UniRef50_Q1K3M3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Desulfuromonas acetoxidans DSM 684|Rep:
D-3-phosphoglycerate dehydrogenase - Desulfuromonas
acetoxidans DSM 684
Length = 528
Score = 58.4 bits (135), Expect = 1e-07
Identities = 27/77 (35%), Positives = 44/77 (57%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG GV+NI +D+A KG+ V N P + + E +M+ LAR + A ++ G+W
Sbjct: 70 RAGIGVENIAMDAANIKGIVVTNTPLGSTTTIAEHAIAMMMSLARLIPQAHESMSQGKWQ 129
Query: 461 RALYTGSELAGKTLAIL 511
+ GS++ KTL ++
Sbjct: 130 STEFLGSDINDKTLGVI 146
Score = 35.5 bits (78), Expect = 1.2
Identities = 23/64 (35%), Positives = 36/64 (56%), Gaps = 1/64 (1%)
Frame = +3
Query: 84 VLIVDGVGAKCAELLN-AYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDQA 260
VLI D + +L + A GI + I+ + LL I N+DAL+VR T V++E++ A
Sbjct: 3 VLISDNFSSAGLKLFDEAEGITADYQPGITHDNLLKIINNYDALIVRGGTTVSEELIFAA 62
Query: 261 *SLR 272
L+
Sbjct: 63 KRLK 66
Score = 35.5 bits (78), Expect = 1.2
Identities = 16/54 (29%), Positives = 31/54 (57%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+G G++GR V M++ +DP++S + + +K+ LED+ AD+I+
Sbjct: 146 IGGGKIGRRVIEYARGLHMHVNLYDPYLSEEVITRLGASKVSLEDLLSTADFIS 199
>UniRef50_A6EBH4 Cluster: Phosphoglycerate dehydrogenase; n=1;
Pedobacter sp. BAL39|Rep: Phosphoglycerate dehydrogenase
- Pedobacter sp. BAL39
Length = 309
Score = 58.4 bits (135), Expect = 1e-07
Identities = 32/77 (41%), Positives = 44/77 (57%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAGAG+DNID A ++ + +INAP N + E LML L + A ++ G+WD
Sbjct: 72 RAGAGLDNIDEAVALERNIHLINAPEGNMDAVGEHAVGLMLSLMNNFRNADMEIRKGKWD 131
Query: 461 RALYTGSELAGKTLAIL 511
R G EL GKT+ I+
Sbjct: 132 REGNRGYELKGKTVGII 148
>UniRef50_A6CKS4 Cluster: Putative uncharacterized protein; n=1;
Bacillus sp. SG-1|Rep: Putative uncharacterized protein
- Bacillus sp. SG-1
Length = 322
Score = 58.4 bits (135), Expect = 1e-07
Identities = 32/78 (41%), Positives = 48/78 (61%), Gaps = 1/78 (1%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R G GVDNID+++A +G+ V NAP AN + E TL+L +R ++ +AL+ G ++
Sbjct: 70 RHGIGVDNIDLEAASDRGILVTNAPFANVNAVAEHVLTLILSGSRQLIQVDSALRNGDFE 129
Query: 461 -RALYTGSELAGKTLAIL 511
R G EL GKTL ++
Sbjct: 130 VRNRKFGIELKGKTLGVV 147
Score = 33.9 bits (74), Expect = 3.6
Identities = 14/55 (25%), Positives = 30/55 (54%), Gaps = 1/55 (1%)
Frame = +1
Query: 508 LGLGRVGR*VATRM-YAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+G G +G+ VA + Y GM+++ +DP+V + + + L ++ +D +T
Sbjct: 147 VGFGNIGQLVAEKCHYGLGMDVLVYDPYVREENVSSYVQLNQSLSEVLASSDIVT 201
>UniRef50_Q81T55 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=41; cellular
organisms|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Bacillus anthracis
Length = 323
Score = 58.0 bits (134), Expect = 2e-07
Identities = 30/80 (37%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA---GRW 457
GAG DNID AG+KG+ V N P + + ELT L+L AR + T + W
Sbjct: 73 GAGYDNIDYTYAGEKGIAVTNTPKVSTEATAELTFALLLAAARRIPEGDTLCRTTGFNGW 132
Query: 458 DRALYTGSELAGKTLAILAL 517
+ G E+ GKT+ I+ L
Sbjct: 133 APLFFLGREVHGKTIGIIGL 152
Score = 42.3 bits (95), Expect = 0.010
Identities = 21/54 (38%), Positives = 32/54 (59%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+GLG +G+ VA R AFGMNI+ P + ++ T + LE++ AD+IT
Sbjct: 150 IGLGEIGKAVAKRAKAFGMNILYTGPNRKPEAESELEATYVTLEELLQTADFIT 203
Score = 34.7 bits (76), Expect = 2.0
Identities = 21/52 (40%), Positives = 32/52 (61%), Gaps = 1/52 (1%)
Frame = +3
Query: 120 ELLNAYGIATTTKAK-ISKEELLMEIPNHDALVVRSATQVTKEVLDQA*SLR 272
ELL + + K + IS +EL + + DAL+ +T+VTKEV+D A SL+
Sbjct: 16 ELLKDHDVEMYDKEELISLDELTERVKDKDALLSLLSTKVTKEVIDAAPSLK 67
>UniRef50_Q0K073 Cluster: D-3-Phosphoglycerate dehydrogenase; n=2;
Burkholderiales|Rep: D-3-Phosphoglycerate dehydrogenase
- Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428
/ Stanier 337)(Cupriavidus necator (strain ATCC 17699 /
H16 / DSM 428 / Stanier337))
Length = 360
Score = 58.0 bits (134), Expect = 2e-07
Identities = 32/85 (37%), Positives = 49/85 (57%), Gaps = 1/85 (1%)
Frame = +2
Query: 284 AGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD- 460
+G+G D ID+D+ + GV V+N G NA S E+T LML + R + + +L+A +
Sbjct: 91 SGSGCDTIDIDACTEAGVAVLNQAGGNADSVAEMTLGLMLAVLRRIAESDRSLRAHNCES 150
Query: 461 RALYTGSELAGKTLAILALAGSADR 535
R G EL G+TL ++ + G A R
Sbjct: 151 REDLMGHELRGRTLGLVGV-GHAGR 174
Score = 33.5 bits (73), Expect = 4.7
Identities = 17/54 (31%), Positives = 28/54 (51%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+G+G GR VA A GM +IG DP + A + + + E++ AD ++
Sbjct: 167 VGVGHAGRRVAALGRALGMRVIGCDPALDAAELSARGAQAVSFEELLRSADIVS 220
>UniRef50_Q031D4 Cluster: Phosphoglycerate dehydrogenase; n=20;
Streptococcaceae|Rep: Phosphoglycerate dehydrogenase -
Lactococcus lactis subsp. cremoris (strain SK11)
Length = 398
Score = 58.0 bits (134), Expect = 2e-07
Identities = 33/90 (36%), Positives = 53/90 (58%), Gaps = 11/90 (12%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW- 457
RAGAG +NI ++ KG+ V NAPG NA + EL ++M+ R++ PA+ L +
Sbjct: 58 RAGAGFNNIPIEKCASKGIVVFNAPGGNANAVKELVLSMMIFGTRNLKPANKWLTGQKGN 117
Query: 458 DRAL----------YTGSELAGKTLAILAL 517
D+A+ ++GSE++GKTL ++ L
Sbjct: 118 DKAIDVAVENGKKAFSGSEISGKTLGVIGL 147
Score = 41.5 bits (93), Expect = 0.018
Identities = 21/57 (36%), Positives = 33/57 (57%), Gaps = 3/57 (5%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQC--AQFHCTKM-ELEDIWPLADYIT 669
+GLG +G VA GM +IG+DP++S + H ++ +L +I+ ADYIT
Sbjct: 145 IGLGNIGSKVANDAQRLGMKVIGYDPYLSIEHAWNLSHHVKRVNDLSEIFEKADYIT 201
>UniRef50_Q7WM64 Cluster: Putative dehydrogenase; n=2;
Bordetella|Rep: Putative dehydrogenase - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 330
Score = 57.6 bits (133), Expect = 3e-07
Identities = 28/76 (36%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
G G + ID+ +A + G+ V+N PGANA S EL + + L + VP A++ G W+
Sbjct: 75 GTGTNMIDLAAAERLGIPVVNTPGANARSVAELALAMAMALLKRTVPLDQAVRQGNWNIR 134
Query: 467 LYTG-SELAGKTLAIL 511
G EL+G +L I+
Sbjct: 135 YEAGLRELSGMSLGIV 150
>UniRef50_Q3Y1E6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=1;
Enterococcus faecium DO|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Enterococcus faecium DO
Length = 386
Score = 57.6 bits (133), Expect = 3e-07
Identities = 34/99 (34%), Positives = 50/99 (50%), Gaps = 9/99 (9%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAS--------- 433
RAG GV+ I+V+ A + G V+N PG NA + EL +L+ +R ++ AS
Sbjct: 55 RAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPIIEASRMVQTLTGP 114
Query: 434 TALKAGRWDRALYTGSELAGKTLAILALAGSADRWPLGC 550
L+ R+ Y G EL GKT+ +L L + L C
Sbjct: 115 NILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSC 153
>UniRef50_Q3CIY1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=2;
Thermoanaerobacter ethanolicus|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Thermoanaerobacter ethanolicus ATCC 33223
Length = 319
Score = 57.6 bits (133), Expect = 3e-07
Identities = 30/77 (38%), Positives = 47/77 (61%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
G GVD+IDV +A + G+ V NAPG N+ +L L+ +LAR + A+T K G+W +
Sbjct: 80 GVGVDSIDVKTANQLGIVVTNAPGTNSEEVADLAFGLLHMLARGLYQANTDTKNGKWIKP 139
Query: 467 LYTGSELAGKTLAILAL 517
+ G L+ KT+ I+ +
Sbjct: 140 V--GISLSKKTIGIIGV 154
>UniRef50_Q6L245 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Thermoplasmatales|Rep: D-3-phosphoglycerate
dehydrogenase - Picrophilus torridus
Length = 299
Score = 57.6 bits (133), Expect = 3e-07
Identities = 30/77 (38%), Positives = 44/77 (57%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG G D+IDVD A +KG+ ++ APG++ S ELT ++ AR ++ + D
Sbjct: 70 RAGIGTDSIDVDYAQEKGIKIVYAPGSSTESVVELTVAFAVIAARQIIKGVENTRKN--D 127
Query: 461 RALYTGSELAGKTLAIL 511
G EL+GKTL I+
Sbjct: 128 FTKLKGIELSGKTLGII 144
Score = 35.5 bits (78), Expect = 1.2
Identities = 19/63 (30%), Positives = 36/63 (57%)
Frame = +3
Query: 84 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDQA* 263
+LI D V E L+ I+++ELL +I ++D ++VRS T++ ++++D A
Sbjct: 5 ILICDPVDGIMIEKLSK-DFDIDNSPDITRDELLKKIGDYDIIIVRSRTKIDRDIIDNAK 63
Query: 264 SLR 272
L+
Sbjct: 64 RLK 66
>UniRef50_Q0FY56 Cluster: Putative phosphoglycerate dehydrogenase
protein; n=1; Fulvimarina pelagi HTCC2506|Rep: Putative
phosphoglycerate dehydrogenase protein - Fulvimarina
pelagi HTCC2506
Length = 322
Score = 57.2 bits (132), Expect = 3e-07
Identities = 32/84 (38%), Positives = 44/84 (52%), Gaps = 3/84 (3%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R GAG+D I V +A + G+ V N P NA S E L++ LAR +V ++ W
Sbjct: 64 RHGAGLDFIPVQAASRLGIAVTNTPSVNAKSVAEHVFGLIICLARRIVENDAGIRRNEWH 123
Query: 461 --RALYTGS-ELAGKTLAILALAG 523
RA GS E+AGK L ++ G
Sbjct: 124 ALRAAAPGSCEIAGKALGLIGYGG 147
>UniRef50_Q8EP33 Cluster: Glycerate dehydrogenase; n=2;
Bacillaceae|Rep: Glycerate dehydrogenase -
Oceanobacillus iheyensis
Length = 314
Score = 56.8 bits (131), Expect = 4e-07
Identities = 31/75 (41%), Positives = 42/75 (56%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
GAG DNID A +KG+ V N PG NA + +L LML AR++ + L+ G W+
Sbjct: 77 GAGYDNIDFKYAREKGIPVTNTPGQNADAVADLAIGLMLATARNIPAKNEELRNGNWE-- 134
Query: 467 LYTGSELAGKTLAIL 511
L G E+ K L I+
Sbjct: 135 LSMGIEIFQKKLGII 149
>UniRef50_Q21A61 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Rhodopseudomonas
palustris BisB18|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Rhodopseudomonas palustris
(strain BisB18)
Length = 321
Score = 56.8 bits (131), Expect = 4e-07
Identities = 30/77 (38%), Positives = 43/77 (55%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
GAG ++ID+ +A GV V+ A GANA S E LML L + V ++ G WD+
Sbjct: 77 GAGTNDIDLAAAKALGVPVLAAVGANAHSVAEHAFMLMLALIKDVRNQDAYVRGGGWDKK 136
Query: 467 LYTGSELAGKTLAILAL 517
Y G EL G+ L ++ +
Sbjct: 137 GYRGRELRGRVLGLVGI 153
>UniRef50_P13443 Cluster: Glycerate dehydrogenase; n=15;
Viridiplantae|Rep: Glycerate dehydrogenase - Cucumis
sativus (Cucumber)
Length = 382
Score = 56.4 bits (130), Expect = 6e-07
Identities = 29/76 (38%), Positives = 45/76 (59%), Gaps = 3/76 (3%)
Frame = +2
Query: 293 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD---R 463
G +N+DV++A K GV V N PG + EL +L L AR +V A ++AGR+D
Sbjct: 96 GYNNVDVNAANKYGVAVGNTPGVLTETTAELAASLSLAAARRIVEADEFMRAGRYDGWLP 155
Query: 464 ALYTGSELAGKTLAIL 511
L+ G+ L G+T+ ++
Sbjct: 156 NLFVGNLLKGQTVGVI 171
>UniRef50_Q3SK87 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=4; Proteobacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Thiobacillus
denitrificans (strain ATCC 25259)
Length = 391
Score = 56.0 bits (129), Expect = 8e-07
Identities = 33/82 (40%), Positives = 48/82 (58%), Gaps = 1/82 (1%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA-GRW 457
RAGAG +NI V ++G+ V NAPGANA + EL ML+ AR++VPA +++
Sbjct: 58 RAGAGTNNIPVKKMSERGLPVFNAPGANANAVKELVIAGMLMGARNLVPALKFVESLDGT 117
Query: 458 DRALYTGSELAGKTLAILALAG 523
D A++ +E K A + L G
Sbjct: 118 DEAMHKATEAGKKQFAGMELPG 139
Score = 36.7 bits (81), Expect = 0.51
Identities = 17/57 (29%), Positives = 32/57 (56%), Gaps = 3/57 (5%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQF--HCTKME-LEDIWPLADYIT 669
+GLG +G +A GMN++G+DP ++ D + + E ++D+ AD++T
Sbjct: 145 IGLGAIGSHIAEAAIRLGMNVVGYDPAITVDAAWRLPSQVKRAENVDDVLRTADFVT 201
>UniRef50_Q4AIL7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding precursor; n=1;
Chlorobium phaeobacteroides BS1|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding
precursor - Chlorobium phaeobacteroides BS1
Length = 312
Score = 56.0 bits (129), Expect = 8e-07
Identities = 29/77 (37%), Positives = 42/77 (54%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R GAG++NID+ SA K V +NAP N + E ++L L ++ A ++ G W
Sbjct: 72 RVGAGMENIDIQSADKHQVVCLNAPEGNRDAVAEQAVGMILTLFNRLLIADAEVRKGIWL 131
Query: 461 RALYTGSELAGKTLAIL 511
R G EL GKT+ I+
Sbjct: 132 REQNRGIELGGKTVGII 148
>UniRef50_Q0RXU8 Cluster: Phosphoglycerate dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: Phosphoglycerate dehydrogenase
- Rhodococcus sp. (strain RHA1)
Length = 325
Score = 56.0 bits (129), Expect = 8e-07
Identities = 34/85 (40%), Positives = 43/85 (50%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG G+DNIDV A + GV V+ GANA+S E T + L R V + G W+
Sbjct: 77 RAGVGLDNIDVKCANEAGVVVVAPLGANAISVAEHTIGMALAAVRRTVELDADCRRGGWE 136
Query: 461 RALYTGSELAGKTLAILALAGSADR 535
R G EL G +L AG+ R
Sbjct: 137 RT--PGRELHGGVWGLLG-AGATGR 158
Score = 34.3 bits (75), Expect = 2.7
Identities = 15/35 (42%), Positives = 21/35 (60%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQ 612
LG G GR A + GM+I+ +DPF A++ AQ
Sbjct: 151 LGAGATGRACARLARSLGMSIVAYDPFADAEKLAQ 185
>UniRef50_A4AN91 Cluster: Predicted dehydrogenase; n=14;
Bacteroidetes|Rep: Predicted dehydrogenase -
Flavobacteriales bacterium HTCC2170
Length = 337
Score = 56.0 bits (129), Expect = 8e-07
Identities = 30/77 (38%), Positives = 45/77 (58%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R GAG++NIDV A KK + + AP N + E T ++L L ++ A+ ++ G+WD
Sbjct: 94 RVGAGLENIDVAYAKKKNIFLAAAPEGNRNAVGEHTLGMLLSLFNNLNKANLEVRNGKWD 153
Query: 461 RALYTGSELAGKTLAIL 511
R G EL GKT+ I+
Sbjct: 154 REGNRGVELDGKTVGII 170
>UniRef50_Q5KN70 Cluster: D-3-phosphoglycerate dehydrogenase 2,
putative; n=2; Filobasidiella neoformans|Rep:
D-3-phosphoglycerate dehydrogenase 2, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 508
Score = 56.0 bits (129), Expect = 8e-07
Identities = 23/73 (31%), Positives = 45/73 (61%)
Frame = +2
Query: 293 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY 472
G + +D++ A K+G+ V N+P +N+ S EL + ++ L+R ++ + ++AG W++
Sbjct: 172 GTNQVDLEHAAKRGIAVFNSPFSNSRSVAELVISEIIALSRQIIDRTHEMRAGIWNKLSK 231
Query: 473 TGSELAGKTLAIL 511
E+ GKTL I+
Sbjct: 232 NCWEIRGKTLGIV 244
Score = 40.3 bits (90), Expect = 0.041
Identities = 19/59 (32%), Positives = 39/59 (66%), Gaps = 2/59 (3%)
Frame = +3
Query: 84 VLIVDGVGAKCAELLNAYG--IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 254
+L+++ + A+ L + G + TKA ++EEL+ ++PN+ A+ +RS T++T +V+D
Sbjct: 101 ILLLENINLDAADYLKSQGYEVDHVTKA-YTEEELIAKLPNYHAIGIRSKTKITAKVID 158
>UniRef50_Q65WI5 Cluster: SerA protein; n=1; Mannheimia
succiniciproducens MBEL55E|Rep: SerA protein -
Mannheimia succiniciproducens (strain MBEL55E)
Length = 326
Score = 55.6 bits (128), Expect = 1e-06
Identities = 29/78 (37%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R G GVD++DV +A + G+ V+ APG+N S E LM A+ +V + ++ G +
Sbjct: 70 RPGVGVDDVDVKTATELGIPVVIAPGSNTRSVAEHAFALMFACAKDIVRSDNEMRKGNFA 129
Query: 461 -RALYTGSELAGKTLAIL 511
R+ Y EL KTLA++
Sbjct: 130 IRSSYKAYELNHKTLALI 147
Score = 34.7 bits (76), Expect = 2.0
Identities = 19/49 (38%), Positives = 29/49 (59%), Gaps = 3/49 (6%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFV---SADQCAQFHCTKMELEDI 645
+G GR+G +A A GMN+ +DPFV + +Q +CT EL+D+
Sbjct: 147 IGYGRIGSILAQMSKAIGMNVKVYDPFVKQGTIEQEGYIYCT--ELDDV 193
>UniRef50_Q1LCR9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Ralstonia metallidurans
CH34|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Ralstonia metallidurans (strain CH34 /
ATCC 43123 / DSM 2839)
Length = 317
Score = 55.6 bits (128), Expect = 1e-06
Identities = 29/83 (34%), Positives = 42/83 (50%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
GAG +NI+ D+A +GV V +AP N+ + +ML +R + LKAG+WD
Sbjct: 77 GAGYENIERDAARMRGVRVCHAPDTNSQVVADHALAMMLAWSRGIAMLDRGLKAGQWDAL 136
Query: 467 LYTGSELAGKTLAILALAGSADR 535
+ GKTL I+ L R
Sbjct: 137 RAPRPGVRGKTLGIVGLGNIGQR 159
>UniRef50_A4YFM2 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Metallosphaera sedula
DSM 5348|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Metallosphaera sedula DSM
5348
Length = 324
Score = 55.6 bits (128), Expect = 1e-06
Identities = 31/90 (34%), Positives = 47/90 (52%), Gaps = 5/90 (5%)
Frame = +2
Query: 281 RAGAGVDN--IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR 454
R GAGVD +D+ +A ++ + + PG N+++ ELT L + L R V+P + ++KAG+
Sbjct: 75 RTGAGVDETRVDLKAAKERDIIITYNPGGNSVAVAELTIMLAIALYRKVIPLALSVKAGK 134
Query: 455 WDRAL---YTGSELAGKTLAILALAGSADR 535
W G EL GK IL R
Sbjct: 135 WSELKPKDTMGHELEGKAWGILGFGNIGKR 164
Score = 36.3 bits (80), Expect = 0.67
Identities = 15/54 (27%), Positives = 31/54 (57%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
LG G +G+ VA + + ++G+DP+VS++ + + LE++ +D I+
Sbjct: 156 LGFGNIGKRVAQLVTSLNCKVLGYDPYVSSEIMEKHGVKSLSLEELLSKSDIIS 209
>UniRef50_O86322 Cluster: POSSIBLE D-3-PHOSPHOGLYCERATE
DEHYDROGENASE SERA2; n=11; Mycobacterium|Rep: POSSIBLE
D-3-PHOSPHOGLYCERATE DEHYDROGENASE SERA2 - Mycobacterium
tuberculosis
Length = 326
Score = 55.2 bits (127), Expect = 1e-06
Identities = 30/89 (33%), Positives = 49/89 (55%), Gaps = 8/89 (8%)
Frame = +2
Query: 302 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR------ 463
N+D+ A G+ V++ P NA + E+T L+L +ARH++PA +++G R
Sbjct: 86 NVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAVARHLIPADADVRSGNIFRDGTIPY 145
Query: 464 ALYTGSELAGKTLAILAL--AGSADRWPL 544
+ G+E+AG T ++ L G A RW L
Sbjct: 146 QRFRGAEIAGLTAGLVGLGAVGRAVRWRL 174
>UniRef50_A6G5P3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: D-3-phosphoglycerate
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 405
Score = 55.2 bits (127), Expect = 1e-06
Identities = 28/73 (38%), Positives = 39/73 (53%)
Frame = +2
Query: 293 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY 472
G D ID++ A + GV V NAP +N S EL ++ L+R + S A GRW +
Sbjct: 75 GTDQIDLEVAAQSGVAVFNAPFSNTRSVAELVIAEIVCLSRQLFERSWAAHEGRWRKDAK 134
Query: 473 TGSELAGKTLAIL 511
E+ GKTL I+
Sbjct: 135 GAHEVRGKTLGII 147
>UniRef50_Q8FPW0 Cluster: Putative uncharacterized protein; n=1;
Corynebacterium efficiens|Rep: Putative uncharacterized
protein - Corynebacterium efficiens
Length = 161
Score = 54.8 bits (126), Expect = 2e-06
Identities = 40/109 (36%), Positives = 45/109 (41%)
Frame = -1
Query: 516 KAKMARVLPASSLPVYRARSHLPAFSAVEAGTTWRARTNINVQVSSHALSALAPGALITP 337
K + VLP S P+ R H P+ A WRA S A L GAL T
Sbjct: 4 KPTIPTVLPKISTPLKEERFHSPSRRVASAAGIWRAVDRSRETACSQAEWMLEVGALATM 63
Query: 336 TPFLPAESTSMLSTPAPARPTTLSFTPGPTPLWSLELLNAQPERRGWVS 190
TP A S LS P PARPT F G + S L A+ RR S
Sbjct: 64 TPASVAAGMSTLSRPTPARPTI--FRLGAAAMTSASTLVAERTRRASAS 110
>UniRef50_Q67M76 Cluster: Phosphoglycerate dehydrogenase, N-terminal
domain; n=1; Symbiobacterium thermophilum|Rep:
Phosphoglycerate dehydrogenase, N-terminal domain -
Symbiobacterium thermophilum
Length = 140
Score = 54.8 bits (126), Expect = 2e-06
Identities = 26/57 (45%), Positives = 36/57 (63%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW 457
G GVDNIDV +A ++G+ V+N P ANA+S E + LA+ VV A++ GRW
Sbjct: 73 GVGVDNIDVAAATERGILVLNTPEANAVSVAEHAIAAIAALAKRVVFMDRAVRDGRW 129
>UniRef50_Q1FF19 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=1;
Clostridium phytofermentans ISDg|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Clostridium phytofermentans ISDg
Length = 316
Score = 54.8 bits (126), Expect = 2e-06
Identities = 31/78 (39%), Positives = 44/78 (56%), Gaps = 1/78 (1%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R G G DNID+ A +G+ V P ANA S E T L+L A+++V A L+ G ++
Sbjct: 70 RHGVGYDNIDIAEATAQGIKVCYTPLANANSVAEHTIMLLLACAKNIVIADKELRQGNYE 129
Query: 461 -RALYTGSELAGKTLAIL 511
R G ++ GKTL I+
Sbjct: 130 IRNQMPGIDVFGKTLGII 147
>UniRef50_Q5KE95 Cluster: Phosphoglycerate dehydrogenase; n=2;
Filobasidiella neoformans|Rep: Phosphoglycerate
dehydrogenase - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 316
Score = 54.8 bits (126), Expect = 2e-06
Identities = 29/84 (34%), Positives = 46/84 (54%), Gaps = 1/84 (1%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
G G D+ID++ +KGV ++N PG N+ ELT +L L L R V L+AG +
Sbjct: 108 GVGYDSIDIEGCKEKGVTLMNCPGENSQVVAELTLSLTLALLRRVPELDRRLRAGETMLS 167
Query: 467 LYT-GSELAGKTLAILALAGSADR 535
+ G L GK + ++ ++ +A R
Sbjct: 168 INNLGRTLRGKVVGMVGISATARR 191
>UniRef50_Q825H6 Cluster: Putative glycerate dehydrogenase; n=1;
Streptomyces avermitilis|Rep: Putative glycerate
dehydrogenase - Streptomyces avermitilis
Length = 325
Score = 54.4 bits (125), Expect = 2e-06
Identities = 34/82 (41%), Positives = 47/82 (57%), Gaps = 4/82 (4%)
Frame = +2
Query: 284 AGAGVDNIDVDSAGKKGVGVIN--APGANALSACELTCTLMLVLARHVVPASTALKAGRW 457
A G D +D+D+A +G+ V N + GA + E T LML LA+ +VPA TAL W
Sbjct: 77 ASHGFDYVDLDAARARGLPVCNIGSSGAEQQNVAEQTFALMLALAKQLVPAHTALVDADW 136
Query: 458 --DRALYTGSELAGKTLAILAL 517
R + +EL+GKTL I+ L
Sbjct: 137 ALPRLQRSITELSGKTLGIVGL 158
>UniRef50_Q49ZM5 Cluster: Putative dehydrogenase; n=1;
Staphylococcus saprophyticus subsp. saprophyticus ATCC
15305|Rep: Putative dehydrogenase - Staphylococcus
saprophyticus subsp. saprophyticus (strain ATCC 15305
/DSM 20229)
Length = 318
Score = 54.4 bits (125), Expect = 2e-06
Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 5/86 (5%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA---GRW 457
GAG +N+D+D A ++ + V N P A+ S ELT L+L +AR + + W
Sbjct: 75 GAGFNNVDIDYARQQNIDVTNTPKASTNSTAELTFALVLAVARRIPEGDKLCRTTGFDGW 134
Query: 458 DRALYTGSELAGKTLAILALA--GSA 529
+ G E++GKT+ I+ L GSA
Sbjct: 135 APLFFRGREVSGKTIGIIGLGEIGSA 160
Score = 37.1 bits (82), Expect = 0.38
Identities = 19/54 (35%), Positives = 29/54 (53%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+GLG +G VA R AF MNI+ P D+ + ++LE + AD++T
Sbjct: 152 IGLGEIGSAVARRAKAFDMNILYTGPHQKVDKEREIGAKYVDLETLLKNADFVT 205
>UniRef50_Q01W77 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Solibacter usitatus
Ellin6076|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Solibacter usitatus (strain
Ellin6076)
Length = 312
Score = 54.4 bits (125), Expect = 2e-06
Identities = 27/75 (36%), Positives = 39/75 (52%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
G G D++D+ +A + GV V N PG A S E T L+ +AR + A + G W+R
Sbjct: 79 GTGTDHVDLAAAARHGVTVANTPGVAARSIAEHTLALLFAVARQIPHMDAATRRGAWERG 138
Query: 467 LYTGSELAGKTLAIL 511
EL GKT ++
Sbjct: 139 --QSMELYGKTCGVI 151
>UniRef50_A7HBU0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=2; Anaeromyxobacter|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Anaeromyxobacter sp. Fw109-5
Length = 313
Score = 54.4 bits (125), Expect = 2e-06
Identities = 27/78 (34%), Positives = 44/78 (56%), Gaps = 3/78 (3%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW--- 457
G GV+++D+D+ ++GV V N PG + + L+L AR VV ++AG W
Sbjct: 74 GVGVNHLDLDACRRRGVLVTNTPGVVTDATADHAMALLLAAARRVVEGDRVVRAGGWTEV 133
Query: 458 DRALYTGSELAGKTLAIL 511
D A G+E+ GKT+ ++
Sbjct: 134 DPAWMLGTEVTGKTVGVV 151
>UniRef50_A0HBX6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Comamonas testosteroni
KF-1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Comamonas testosteroni KF-1
Length = 320
Score = 54.4 bits (125), Expect = 2e-06
Identities = 27/75 (36%), Positives = 42/75 (56%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
GAGVD++D+++A +GV V A ANA + E LML L R + ++AG W +
Sbjct: 82 GAGVDSVDMEAARTQGVAVAVAQAANAPAVAEHALALMLALVRQLPQLDQQVRAGGWAGS 141
Query: 467 LYTGSELAGKTLAIL 511
+ G + G T+ I+
Sbjct: 142 NWQGRDFRGSTVGIV 156
>UniRef50_A7EUN0 Cluster: Formate dehydrogenase; n=2;
Sclerotiniaceae|Rep: Formate dehydrogenase - Sclerotinia
sclerotiorum 1980
Length = 436
Score = 54.4 bits (125), Expect = 2e-06
Identities = 31/88 (35%), Positives = 48/88 (54%), Gaps = 4/88 (4%)
Frame = +2
Query: 284 AGAGVDNIDVDSAGKK--GVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW 457
AG G D++D+++A K G+ V G+N +S E +LVL R+ VPA ++AG W
Sbjct: 154 AGIGSDHVDLNAANKTNGGITVAEVTGSNVVSVAEHVVMTILVLVRNFVPAHEQIQAGEW 213
Query: 458 DRALYTGSE--LAGKTLAILALAGSADR 535
D A +E L GK + +A+ +R
Sbjct: 214 DVAAAAKNEFDLEGKVVGTVAVGRIGER 241
>UniRef50_Q88YI0 Cluster: Phosphoglycerate dehydrogenase; n=5;
Bacilli|Rep: Phosphoglycerate dehydrogenase -
Lactobacillus plantarum
Length = 324
Score = 54.0 bits (124), Expect = 3e-06
Identities = 28/80 (35%), Positives = 42/80 (52%), Gaps = 3/80 (3%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA---GRW 457
GAG +NID+ +A K+ + V N P +A++ E T L++ LA +V ++ W
Sbjct: 75 GAGTNNIDIAAAAKRQIPVTNTPNVSAVATAESTVGLIISLAHRIVEGDHLMRTSGFNGW 134
Query: 458 DRALYTGSELAGKTLAILAL 517
+ G L GKTL IL L
Sbjct: 135 APLFFLGHNLQGKTLGILGL 154
>UniRef50_Q83AZ4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=11; Bacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Coxiella burnetii
Length = 388
Score = 54.0 bits (124), Expect = 3e-06
Identities = 35/90 (38%), Positives = 47/90 (52%), Gaps = 11/90 (12%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPA---------- 430
RAG GV+NI V GV V+N PGANA + EL T +L+ +RH+ PA
Sbjct: 57 RAGVGVNNIPVRPLTLSGVPVLNTPGANANAVKELVITGILLASRHIYPALDYARHIEGD 116
Query: 431 -STALKAGRWDRALYTGSELAGKTLAILAL 517
T ++ ++G EL GKTL I+ L
Sbjct: 117 DETITHQVEKNKKRFSGFELPGKTLGIIGL 146
>UniRef50_Q30V14 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=3; Desulfovibrio|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Desulfovibrio desulfuricans (strain G20)
Length = 305
Score = 54.0 bits (124), Expect = 3e-06
Identities = 28/79 (35%), Positives = 43/79 (54%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R G G+DN+D+++A +G+ V N P + ELT L L L R V L++G W
Sbjct: 75 RCGTGMDNVDMEAARARGIAVRNTPDGPTQAVAELTLGLALDLMRQVSRMDRELRSGVWK 134
Query: 461 RALYTGSELAGKTLAILAL 517
+ + G+ L GK L I+ +
Sbjct: 135 KRM--GNLLGGKRLGIVGM 151
>UniRef50_A7HM61 Cluster: Glyoxylate reductase; n=1;
Fervidobacterium nodosum Rt17-B1|Rep: Glyoxylate
reductase - Fervidobacterium nodosum Rt17-B1
Length = 317
Score = 54.0 bits (124), Expect = 3e-06
Identities = 24/78 (30%), Positives = 46/78 (58%), Gaps = 3/78 (3%)
Frame = +2
Query: 293 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDR 463
G +NID+++A ++G+ V N PG + ++ L+L +AR +V + ++ G+ W
Sbjct: 75 GYNNIDIEAAKERGIYVTNTPGVLTEATADIAFALILAVARRIVESDKFVREGKFVGWKP 134
Query: 464 ALYTGSELAGKTLAILAL 517
L+ G +L GKTL ++ +
Sbjct: 135 KLFLGYDLYGKTLGVIGM 152
Score = 36.3 bits (80), Expect = 0.67
Identities = 16/55 (29%), Positives = 35/55 (63%), Gaps = 1/55 (1%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQC-AQFHCTKMELEDIWPLADYIT 669
+G+GR+G+ VA R FGMNI+ ++ ++ Q++ + ++++ ++DYI+
Sbjct: 150 IGMGRIGQAVARRALGFGMNIVYYNRNRLPEEIEKQYNAKYVNIDELVEISDYIS 204
>UniRef50_A2A023 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Flexibacteraceae|Rep: D-3-phosphoglycerate dehydrogenase
- Microscilla marina ATCC 23134
Length = 316
Score = 54.0 bits (124), Expect = 3e-06
Identities = 28/77 (36%), Positives = 42/77 (54%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAGAG+D ID+ +A +G+ V+NAP N + E T ++L L +V A +K W
Sbjct: 71 RAGAGLDKIDLSAANARGIKVLNAPEGNRDAVGEQTIGMLLSLLHNVQRADWEVKNFAWK 130
Query: 461 RALYTGSELAGKTLAIL 511
R G EL K + ++
Sbjct: 131 REANRGVELMDKVVGVI 147
>UniRef50_Q8Y3L1 Cluster: Lmo2824 protein; n=14; Bacillales|Rep:
Lmo2824 protein - Listeria monocytogenes
Length = 395
Score = 53.6 bits (123), Expect = 4e-06
Identities = 33/89 (37%), Positives = 48/89 (53%), Gaps = 10/89 (11%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALK----- 445
RAGAGV+NI V++ +KG+ V N PGANA + EL + V AR ++ + +K
Sbjct: 55 RAGAGVNNIPVENCSEKGIVVFNTPGANANAVKELVLASLFVSARPILEGTEWVKELPAE 114
Query: 446 -----AGRWDRALYTGSELAGKTLAILAL 517
+ + G+ELAGK L I+ L
Sbjct: 115 DDVEQKVEAGKKAFAGTELAGKKLGIIGL 143
Score = 41.9 bits (94), Expect = 0.013
Identities = 20/57 (35%), Positives = 32/57 (56%), Gaps = 3/57 (5%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHC---TKMELEDIWPLADYIT 669
+GLG +G VA + GM+++G+DPFVS D + M +E++ DY+T
Sbjct: 141 IGLGAIGALVANDALSLGMDVVGYDPFVSVDTAWRISKEVERAMTIEEVLATCDYLT 197
>UniRef50_A0VQR0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Dinoroseobacter shibae
DFL 12|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Dinoroseobacter shibae DFL
12
Length = 316
Score = 53.6 bits (123), Expect = 4e-06
Identities = 27/75 (36%), Positives = 40/75 (53%), Gaps = 1/75 (1%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
G G+DNID+ + +G+ V A GAN S E T L+L R ++ ++ G W R
Sbjct: 74 GTGLDNIDMAACAARGISVHPATGANTRSVAEYVITAALMLTRRAFMSTPEMQEGAWPRG 133
Query: 467 -LYTGSELAGKTLAI 508
L G E+AG+ L +
Sbjct: 134 PLGEGGEIAGRKLGL 148
>UniRef50_Q5KQ73 Cluster: D-3-phosphoglycerate dehydrogenase,
putative; n=3; Filobasidiella neoformans|Rep:
D-3-phosphoglycerate dehydrogenase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 594
Score = 53.6 bits (123), Expect = 4e-06
Identities = 30/79 (37%), Positives = 42/79 (53%), Gaps = 2/79 (2%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
+ G GVD ID+ +A K G+ V+N PG NA + EL +ML LAR ++ G
Sbjct: 104 KQGTGVDKIDIVNAKKLGIPVMNTPGVNAQAVAELAFGMMLSLARQTPSIDRKIRKGASV 163
Query: 461 RAL--YTGSELAGKTLAIL 511
L + G L GKTL ++
Sbjct: 164 TKLDGWKGQMLYGKTLGVI 182
>UniRef50_Q8CPW2 Cluster: Glycerate dehydrogenase; n=4;
Staphylococcus|Rep: Glycerate dehydrogenase -
Staphylococcus epidermidis (strain ATCC 12228)
Length = 323
Score = 53.2 bits (122), Expect = 5e-06
Identities = 28/78 (35%), Positives = 43/78 (55%), Gaps = 3/78 (3%)
Frame = +2
Query: 293 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR--- 463
G DNID+ A K GV V N P + EL TLML +AR ++ A++ ++ G+W
Sbjct: 77 GFDNIDISLAKKHGVVVTNTPHVLTETTAELGFTLMLTVARRIIEATSYIQEGKWKSWGP 136
Query: 464 ALYTGSELAGKTLAILAL 517
L +G ++ G T+ I +
Sbjct: 137 YLLSGKDVYGATVGIFGM 154
>UniRef50_Q82U25 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=3; Nitrosomonadaceae|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Nitrosomonas
europaea
Length = 311
Score = 53.2 bits (122), Expect = 5e-06
Identities = 28/79 (35%), Positives = 44/79 (55%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R G G+DN+D+++A + + V N P A A + ELT LML R + +++ G W
Sbjct: 77 RCGTGMDNVDLEAARRLNIQVSNTPEAPAQAVAELTLGLMLDCLRQINRIDRSVRQGEWP 136
Query: 461 RALYTGSELAGKTLAILAL 517
R+ G LA +T+ I+ L
Sbjct: 137 RS--QGRLLAARTVGIVGL 153
>UniRef50_Q1WVK4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Lactobacillus salivarius subsp. salivarius UCC118|Rep:
D-3-phosphoglycerate dehydrogenase - Lactobacillus
salivarius subsp. salivarius (strain UCC118)
Length = 394
Score = 53.2 bits (122), Expect = 5e-06
Identities = 36/99 (36%), Positives = 49/99 (49%), Gaps = 9/99 (9%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHV-VPASTALKAGRW 457
RAGAGV+NI ++ A +G V N PG+NA + EL T++L+ R V A K
Sbjct: 55 RAGAGVNNIPLEKATSQGTAVFNTPGSNANAVKELIITMLLLSVRPVFASVKWAQKLAGA 114
Query: 458 DRALYT--------GSELAGKTLAILALAGSADRWPLGC 550
D +L T G+EL GK + I+ L R C
Sbjct: 115 DVSLQTEKGKNHFAGTELYGKKIGIIGLGNIGSRVAKAC 153
Score = 38.3 bits (85), Expect = 0.17
Identities = 20/57 (35%), Positives = 33/57 (57%), Gaps = 3/57 (5%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQF--HCTKME-LEDIWPLADYIT 669
+GLG +G VA GM +IG+DP++S ++ Q + E LE++ +D+IT
Sbjct: 140 IGLGNIGSRVAKACMDLGMKVIGYDPYISVEKAWQLSNDIPRAESLEELLEQSDFIT 196
>UniRef50_Q03YV3 Cluster: Lactate dehydrogenase related enzyme; n=1;
Leuconostoc mesenteroides subsp. mesenteroides ATCC
8293|Rep: Lactate dehydrogenase related enzyme -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 314
Score = 53.2 bits (122), Expect = 5e-06
Identities = 26/78 (33%), Positives = 46/78 (58%), Gaps = 1/78 (1%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R G G D +DVD+A ++G+ V+N P A + S E + +L +++++ S A+ W+
Sbjct: 70 RNGVGYDAVDVDAATQRGIYVVNTPKALSGSVAETAVSELLAISKNLYQDSKAIHDDNWN 129
Query: 461 -RALYTGSELAGKTLAIL 511
R + G ++ GKT+ IL
Sbjct: 130 YRKAHPGRDIEGKTVGIL 147
Score = 35.5 bits (78), Expect = 1.2
Identities = 18/53 (33%), Positives = 29/53 (54%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYI 666
LG GR+G+ VA ++ F + +I FDPF + ++ E I+ ADY+
Sbjct: 147 LGFGRIGQQVAKKLSGFDVKVIAFDPFAKDVPGVEL----VDRETIFKTADYV 195
>UniRef50_Q82XE1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=5; Proteobacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Nitrosomonas
europaea
Length = 403
Score = 52.8 bits (121), Expect = 7e-06
Identities = 31/90 (34%), Positives = 49/90 (54%), Gaps = 11/90 (12%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAGAG +NI V+ +G+ V N PGANA + EL ML+ +R+++PA ++ D
Sbjct: 63 RAGAGTNNIPVNQMSARGIPVFNTPGANANAVRELVLAGMLMASRNLIPALRFVETLEGD 122
Query: 461 -----------RALYTGSELAGKTLAILAL 517
+ ++G EL G+TL ++ L
Sbjct: 123 DQSFNLQVEAGKKQFSGLELPGRTLGVIGL 152
Score = 34.3 bits (75), Expect = 2.7
Identities = 13/31 (41%), Positives = 21/31 (67%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSAD 600
+GLG++GR VA GM ++G+DP ++ D
Sbjct: 150 IGLGKIGRQVADIAIKLGMKVLGYDPKITID 180
>UniRef50_Q6AMI7 Cluster: Related to D-3-phosphoglycerate
dehydrogenase; n=1; Desulfotalea psychrophila|Rep:
Related to D-3-phosphoglycerate dehydrogenase -
Desulfotalea psychrophila
Length = 393
Score = 52.8 bits (121), Expect = 7e-06
Identities = 32/91 (35%), Positives = 51/91 (56%), Gaps = 12/91 (13%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHV------VPASTAL 442
RAGAG +N++V+ A KKG+ V N PGANA + +L ++ V R++ + TA+
Sbjct: 56 RAGAGTNNVNVERATKKGICVFNTPGANANAVVDLVFPMLGVWKRNIFNGINFCKSLTAV 115
Query: 443 KAGRWD------RALYTGSELAGKTLAILAL 517
+ D ++ Y G E+AGK L ++ L
Sbjct: 116 DPDKVDSVVEAQKSAYKGEEIAGKNLTVVGL 146
>UniRef50_Q3A6W9 Cluster: 3-phosphoglycerate dehydrogenase; n=1;
Pelobacter carbinolicus DSM 2380|Rep: 3-phosphoglycerate
dehydrogenase - Pelobacter carbinolicus (strain DSM 2380
/ Gra Bd 1)
Length = 321
Score = 52.8 bits (121), Expect = 7e-06
Identities = 26/79 (32%), Positives = 41/79 (51%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG+G+DN+D+D + ++ P A + EL +ML L+R ++ A L+ G W
Sbjct: 68 RAGSGLDNVDLDYLRNHDLKLVRIPQPGARAVAELAFGMMLALSRQILVADQLLRKGTWA 127
Query: 461 RALYTGSELAGKTLAILAL 517
+ G L K L I+ L
Sbjct: 128 KHQLRGHLLVNKQLGIVGL 146
>UniRef50_Q4IV69 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic domain:D- isomer specific
2-hydroxyacid dehydrogenase, NAD binding domain; n=1;
Azotobacter vinelandii AvOP|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic domain:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD binding domain
- Azotobacter vinelandii AvOP
Length = 319
Score = 52.8 bits (121), Expect = 7e-06
Identities = 24/57 (42%), Positives = 36/57 (63%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW 457
G+G D ID+D A ++G+ V N+P ANA S +L L++ R++ A L+AGRW
Sbjct: 77 GSGYDGIDLDHARQRGIVVTNSPAANAASVADLAMGLLISSVRNLPAARQYLEAGRW 133
>UniRef50_A6LZ51 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Clostridium
beijerinckii NCIMB 8052|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Clostridium
beijerinckii NCIMB 8052
Length = 320
Score = 52.8 bits (121), Expect = 7e-06
Identities = 28/78 (35%), Positives = 44/78 (56%), Gaps = 1/78 (1%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
+ GAG DN+D+D+ + G+ NA G NA + E L+L +++ + +K +
Sbjct: 74 QTGAGFDNVDIDACTQYGIWAANAAGVNAQAVAEHVMALILSYYKNIPFLDSFIKNKIDE 133
Query: 461 RAL-YTGSELAGKTLAIL 511
L YTGSEL GKT+ I+
Sbjct: 134 NELQYTGSELKGKTIGII 151
>UniRef50_A1G3C5 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Salinispora arenicola
CNS205|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Salinispora arenicola
CNS205
Length = 345
Score = 52.8 bits (121), Expect = 7e-06
Identities = 29/86 (33%), Positives = 43/86 (50%), Gaps = 1/86 (1%)
Frame = +2
Query: 284 AGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR 463
+G GVDNID+ +A + GV V N PG E L++++ R + + G W++
Sbjct: 72 SGRGVDNIDIPAASRAGVVVANNPGLGGKPVSEHALGLLIMITRDLTAVARDAMTGAWEK 131
Query: 464 ALYTGS-ELAGKTLAILALAGSADRW 538
L T EL G TL I+ G+ W
Sbjct: 132 RLTTRRVELTGGTLGIVG-CGNVGGW 156
Score = 41.1 bits (92), Expect = 0.024
Identities = 22/56 (39%), Positives = 36/56 (64%), Gaps = 2/56 (3%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYA-FGMNIIGFDPFVSADQCAQFHCTKME-LEDIWPLADYIT 669
+G G VG +A R A F M ++ +DP+VSA+Q AQ TK++ L+ + AD+++
Sbjct: 148 VGCGNVGGWMARRASAGFQMRVLAYDPYVSAEQMAQVGATKVDNLDKLLAEADFVS 203
>UniRef50_A7P8C8 Cluster: Chromosome chr3 scaffold_8, whole genome
shotgun sequence; n=3; core eudicotyledons|Rep:
Chromosome chr3 scaffold_8, whole genome shotgun
sequence - Vitis vinifera (Grape)
Length = 418
Score = 52.8 bits (121), Expect = 7e-06
Identities = 27/76 (35%), Positives = 44/76 (57%), Gaps = 3/76 (3%)
Frame = +2
Query: 293 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD---R 463
G +N+DV++A K GV V N PG + EL +L + AR +V A ++AG +D
Sbjct: 96 GYNNVDVNAANKYGVAVGNTPGVLTETTAELAASLSMAAARRIVEADEFMRAGLYDGWLP 155
Query: 464 ALYTGSELAGKTLAIL 511
L+ G+ L G+T+ ++
Sbjct: 156 HLFVGNLLRGQTVGVI 171
>UniRef50_Q6MY49 Cluster: NAD-dependant D-isomer specific
2-hydroxyacid dehydrogenase, putative; n=5;
Eurotiomycetidae|Rep: NAD-dependant D-isomer specific
2-hydroxyacid dehydrogenase, putative - Aspergillus
fumigatus (Sartorya fumigata)
Length = 335
Score = 52.8 bits (121), Expect = 7e-06
Identities = 27/79 (34%), Positives = 41/79 (51%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
GAG DNID+ + +KG+ V + P A + ++ LM+ R +AL+AG+W
Sbjct: 84 GAGYDNIDIPACSEKGIAVSSTPVAVNHATADVGIFLMIGALRQAYIPLSALRAGQWQGK 143
Query: 467 LYTGSELAGKTLAILALAG 523
G + GK L IL + G
Sbjct: 144 TTLGHDPQGKVLGILGMGG 162
>UniRef50_A4R4W0 Cluster: Formate dehydrogenase; n=1; Magnaporthe
grisea|Rep: Formate dehydrogenase - Magnaporthe grisea
(Rice blast fungus) (Pyricularia grisea)
Length = 364
Score = 52.8 bits (121), Expect = 7e-06
Identities = 32/89 (35%), Positives = 48/89 (53%), Gaps = 4/89 (4%)
Frame = +2
Query: 284 AGAGVDNIDVDSAGKK--GVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW 457
AG G D++D+++A K G+ V G+N +S E +LVL R+ VPA ++ G W
Sbjct: 162 AGIGSDHVDLNAANKTNGGITVAEVTGSNVVSVAEHVLMTILVLVRNFVPALEMIQTGEW 221
Query: 458 DRALYTGSE--LAGKTLAILALAGSADRW 538
D A +E L GK + +A+ GS W
Sbjct: 222 DVAGAAKNEYDLEGKVVGTVAV-GSIGSW 249
>UniRef50_O58320 Cluster: Glyoxylate reductase; n=16; cellular
organisms|Rep: Glyoxylate reductase - Pyrococcus
horikoshii
Length = 334
Score = 52.8 bits (121), Expect = 7e-06
Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 7/82 (8%)
Frame = +2
Query: 293 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR--- 463
G DNID++ A K+G+ V N P + +L L+L ARHVV +++G W +
Sbjct: 77 GYDNIDIEEATKRGIYVTNTPDVLTDATADLAFALLLATARHVVKGDRFVRSGEWKKRGV 136
Query: 464 ----ALYTGSELAGKTLAILAL 517
+ G ++ GKT+ I+ L
Sbjct: 137 AWHPKWFLGYDVYGKTIGIIGL 158
>UniRef50_A7CY19 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Opitutaceae bacterium
TAV2|Rep: D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Opitutaceae bacterium TAV2
Length = 318
Score = 52.4 bits (120), Expect = 1e-05
Identities = 28/77 (36%), Positives = 43/77 (55%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
G G+D IDV A K + V+ PG N + E T L+L L ++++ + + ++G W R
Sbjct: 77 GIGLDKIDVAHATSKKIPVLFTPGVNHTTVAEHTFLLLLALEKNILFHTDSTRSGGWKRK 136
Query: 467 LYTGSELAGKTLAILAL 517
TG EL KT+ I+ L
Sbjct: 137 --TGHELLAKTIGIVGL 151
Score = 39.9 bits (89), Expect = 0.054
Identities = 21/55 (38%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMEL-EDIWPLADYIT 669
+GLGR+G+ VA R AFGM +I +D + Q + ++ E+I+ ADYI+
Sbjct: 149 VGLGRIGKEVAIRARAFGMEVIAYDIYWDEAFAKQHNVKRVATKEEIFTSADYIS 203
>UniRef50_A6T665 Cluster: Putative D-3-phosphoglycerate
dehydrogenase; n=1; Klebsiella pneumoniae subsp.
pneumoniae MGH 78578|Rep: Putative D-3-phosphoglycerate
dehydrogenase - Klebsiella pneumoniae subsp. pneumoniae
MGH 78578
Length = 342
Score = 52.4 bits (120), Expect = 1e-05
Identities = 26/55 (47%), Positives = 35/55 (63%)
Frame = +2
Query: 302 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
NID +A +G+ V+ PG NA +A ELT LML LARH+ + ALK G + +A
Sbjct: 79 NIDTQAAQARGIRVLYTPGRNADAAAELTLGLMLSLARHIPQSHAALKRGEFTQA 133
Score = 38.3 bits (85), Expect = 0.17
Identities = 20/54 (37%), Positives = 31/54 (57%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+G G +GR VA AFGM ++ DPFV+A+ + K LE ++ AD ++
Sbjct: 174 VGYGNIGRRVARIARAFGMAVLVVDPFVAAEDINEPGLQKTTLEALFREADIVS 227
>UniRef50_A1JTE6 Cluster: Putative oxidoreductase; n=1; Yersinia
enterocolitica subsp. enterocolitica 8081|Rep: Putative
oxidoreductase - Yersinia enterocolitica serotype O:8 /
biotype 1B (strain 8081)
Length = 338
Score = 52.4 bits (120), Expect = 1e-05
Identities = 25/48 (52%), Positives = 35/48 (72%)
Frame = +2
Query: 302 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALK 445
NIDV++A ++G+ V+ PG N+ +A ELT LML LARH+ A +ALK
Sbjct: 79 NIDVNAATERGIPVVYTPGRNSDAAAELTIALMLNLARHIPQAHSALK 126
Score = 33.9 bits (74), Expect = 3.6
Identities = 17/54 (31%), Positives = 30/54 (55%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+G G +G+ V AFGM ++ DP+VS + + K LE ++ +D++T
Sbjct: 170 VGYGSIGQRVGRIARAFGMQLLVADPYVSEVELDEPGIHKTTLERLFSQSDFVT 223
>UniRef50_A0QQ27 Cluster: Glyoxylate reductase; n=4;
Mycobacterium|Rep: Glyoxylate reductase - Mycobacterium
smegmatis (strain ATCC 700084 / mc(2)155)
Length = 322
Score = 52.4 bits (120), Expect = 1e-05
Identities = 35/89 (39%), Positives = 48/89 (53%), Gaps = 4/89 (4%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR-W 457
+ GAGV+ IDV++A + G+ V N PGANA S E T LML R + A +AGR W
Sbjct: 77 KLGAGVNTIDVETATQLGILVANMPGANAPSVAEGTVLLMLAALRRLPQLDRATRAGRGW 136
Query: 458 --DRAL-YTGSELAGKTLAILALAGSADR 535
D L T ++ G T+ ++ A R
Sbjct: 137 PTDPTLGDTVRDIGGCTVGLVGYGNVAKR 165
>UniRef50_Q0PQJ5 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=1; Endoriftia persephone
'Hot96_1+Hot96_2'|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase - Endoriftia persephone 'Hot96_1+Hot96_2'
Length = 204
Score = 52.0 bits (119), Expect = 1e-05
Identities = 34/90 (37%), Positives = 49/90 (54%), Gaps = 11/90 (12%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPA---STAL--- 442
RAGAGV+NI VD +G+ V NAPGANA + EL ML+ AR++ + +T L
Sbjct: 56 RAGAGVNNIPVDKMTARGISVFNAPGANANAVKELVVAGMLLAARNISQSWKFATGLEGD 115
Query: 443 -----KAGRWDRALYTGSELAGKTLAILAL 517
K + + G EL G+T+ ++ L
Sbjct: 116 DAVISKNVESGKKNFVGFELPGRTMGVIGL 145
>UniRef50_A3ZW64 Cluster: Phosphoglycerate dehydrogenase, putative;
n=1; Blastopirellula marina DSM 3645|Rep:
Phosphoglycerate dehydrogenase, putative -
Blastopirellula marina DSM 3645
Length = 320
Score = 52.0 bits (119), Expect = 1e-05
Identities = 26/77 (33%), Positives = 42/77 (54%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R G G D+++V +A ++ + V PG S E T ++L + R+V+ + ++AG WD
Sbjct: 71 RVGVGYDSVNVPAATEQNIAVCRTPGTLHQSVVEHTIGMILAIYRNVISQNKQVRAGDWD 130
Query: 461 RALYTGSELAGKTLAIL 511
R G GKTL I+
Sbjct: 131 RT--AGPRAYGKTLGII 145
>UniRef50_A1HMI9 Cluster: Phosphoglycerate dehydrogenase; n=1;
Thermosinus carboxydivorans Nor1|Rep: Phosphoglycerate
dehydrogenase - Thermosinus carboxydivorans Nor1
Length = 326
Score = 52.0 bits (119), Expect = 1e-05
Identities = 30/79 (37%), Positives = 41/79 (51%), Gaps = 2/79 (2%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
+ G GVDNID+ +A G+ V N PG NA S ELT +++ L R + K G W
Sbjct: 72 KTGVGVDNIDLAAAKTLGIPVANTPGGNATSVAELTLGMIINLYRKINILDRETKKGNWM 131
Query: 461 RALYTGS--ELAGKTLAIL 511
+ S E+ GKT I+
Sbjct: 132 SWEFRPSSYEVKGKTHGII 150
>UniRef50_Q0CUD5 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 743
Score = 52.0 bits (119), Expect = 1e-05
Identities = 26/77 (33%), Positives = 41/77 (53%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
G G++ ID D+ K+G+ ++N PGANA EL TL L +AR + +T + +
Sbjct: 505 GVGIEKIDQDACVKRGIKILNTPGANARDVAELVVTLALSVARGIRSITTRQMSKPVPKE 564
Query: 467 LYTGSELAGKTLAILAL 517
G L KT+ I+ +
Sbjct: 565 TCNGLTLYQKTIGIIGM 581
>UniRef50_A2QX18 Cluster: Contig An11c0250, complete genome; n=3;
Trichocomaceae|Rep: Contig An11c0250, complete genome -
Aspergillus niger
Length = 336
Score = 52.0 bits (119), Expect = 1e-05
Identities = 28/77 (36%), Positives = 43/77 (55%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
GAG D ID ++ K+G+ V NAP + +L L+L R++ PA +L AG + +
Sbjct: 87 GAGYDPIDTEACAKRGIIVTNAPDPVTDATADLAVLLLLGALRNLNPAIRSLYAGTFKQG 146
Query: 467 LYTGSELAGKTLAILAL 517
+ G + GKTL IL +
Sbjct: 147 VGFGHDPQGKTLGILGM 163
>UniRef50_O28495 Cluster: 2-hydroxyacid dehydrogenase, putative;
n=4; Archaea|Rep: 2-hydroxyacid dehydrogenase, putative
- Archaeoglobus fulgidus
Length = 323
Score = 52.0 bits (119), Expect = 1e-05
Identities = 30/78 (38%), Positives = 43/78 (55%), Gaps = 3/78 (3%)
Frame = +2
Query: 293 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR--- 463
G +NIDV++A K + V N G NALS E T L L R ++ A ++ +GRW++
Sbjct: 80 GYNNIDVEAAKKLSITVANVGGVNALSVAEHTVMFALALLRRLIYAHNSVLSGRWEQDEM 139
Query: 464 ALYTGSELAGKTLAILAL 517
A EL GKT I+ +
Sbjct: 140 ANLGVYELHGKTWGIIGM 157
>UniRef50_Q0W672 Cluster: Glycerate dehydrogenase; n=2; Archaea|Rep:
Glycerate dehydrogenase - Uncultured methanogenic
archaeon RC-I
Length = 319
Score = 52.0 bits (119), Expect = 1e-05
Identities = 25/73 (34%), Positives = 41/73 (56%)
Frame = +2
Query: 293 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY 472
G D++D+D+A KGV V NAPG + + E ++L R + A ++ ++D +
Sbjct: 75 GYDDVDLDAATLKGVAVANAPGYSNEAVAEHVFAMLLSFIRRISEADFWIREEKFDCTAF 134
Query: 473 TGSELAGKTLAIL 511
G EL GKT+ I+
Sbjct: 135 EGRELRGKTMGII 147
>UniRef50_P40054 Cluster: D-3-phosphoglycerate dehydrogenase 1;
n=35; Eukaryota|Rep: D-3-phosphoglycerate dehydrogenase
1 - Saccharomyces cerevisiae (Baker's yeast)
Length = 469
Score = 52.0 bits (119), Expect = 1e-05
Identities = 25/73 (34%), Positives = 40/73 (54%)
Frame = +2
Query: 293 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY 472
G + +D+D A +G+ V N+P +N+ S EL ++ LAR + S L G W++
Sbjct: 132 GTNQVDLDYATSRGIAVFNSPFSNSRSVAELVIAEIISLARQLGDRSIELHTGTWNKVAA 191
Query: 473 TGSELAGKTLAIL 511
E+ GKTL I+
Sbjct: 192 RCWEVRGKTLGII 204
>UniRef50_P0A9T3 Cluster: D-3-phosphoglycerate dehydrogenase; n=185;
Bacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Shigella flexneri
Length = 410
Score = 52.0 bits (119), Expect = 1e-05
Identities = 26/73 (35%), Positives = 39/73 (53%)
Frame = +2
Query: 293 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY 472
G + +D+D+A K+G+ V NAP +N S EL +L+L R V A+ G W++
Sbjct: 85 GTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAA 144
Query: 473 TGSELAGKTLAIL 511
E GK L I+
Sbjct: 145 GSFEARGKKLGII 157
>UniRef50_Q8R8Q2 Cluster: Lactate dehydrogenase and related
dehydrogenases; n=8; cellular organisms|Rep: Lactate
dehydrogenase and related dehydrogenases -
Thermoanaerobacter tengcongensis
Length = 358
Score = 51.6 bits (118), Expect = 2e-05
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPG-ANALSACELTCTLMLVLARHVVPASTALKAGRW 457
R G G D ID++SA KKG V G + E L+L + R V AS +K G+W
Sbjct: 100 RHGIGYDAIDIESATKKGTIVTIVEGIVEREAVAENAVALLLDVMRKVREASIKVKEGKW 159
Query: 458 -DRALYTGSELAGKTLAILALAGSADR 535
+RA + G E+ GKT I+ + R
Sbjct: 160 HERANFIGYEIKGKTAGIIGIGNIGSR 186
Score = 33.9 bits (74), Expect = 3.6
Identities = 16/55 (29%), Positives = 31/55 (56%), Gaps = 1/55 (1%)
Frame = +1
Query: 508 LGLGRVGR*VATRM-YAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+G+G +G VA + Y FG +I +DP +S ++ + + LE++ +D I+
Sbjct: 178 IGIGNIGSRVAEILKYGFGAEVIAYDPNLSKEEIIKREARPVSLEELLRSSDIIS 232
>UniRef50_Q81N95 Cluster: D-3-phosphoglycerate dehydrogenase,
putative; n=19; Bacteria|Rep: D-3-phosphoglycerate
dehydrogenase, putative - Bacillus anthracis
Length = 390
Score = 51.6 bits (118), Expect = 2e-05
Identities = 30/88 (34%), Positives = 49/88 (55%), Gaps = 9/88 (10%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAGAGV+NI V+ +KG+ V N PGANA + EL +++ +R+++ + K +
Sbjct: 56 RAGAGVNNIPVERCTEKGIVVFNTPGANANAVKELIIASLIMSSRNIINGVSWTKNLEGE 115
Query: 461 ---------RALYTGSELAGKTLAILAL 517
+ + GSE+AGK L ++ L
Sbjct: 116 EVPQLVESGKKQFVGSEIAGKRLGVIGL 143
Score = 42.3 bits (95), Expect = 0.010
Identities = 20/57 (35%), Positives = 34/57 (59%), Gaps = 3/57 (5%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQF--HCTK-MELEDIWPLADYIT 669
+GLG +G VA A GM+++G+DP++S + + H + L++I+ DYIT
Sbjct: 141 IGLGAIGALVANDALALGMDVVGYDPYISVETAWRLSTHVQRAFSLDEIFATCDYIT 197
>UniRef50_Q5FUD9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Gluconobacter oxydans|Rep: D-3-phosphoglycerate
dehydrogenase - Gluconobacter oxydans (Gluconobacter
suboxydans)
Length = 314
Score = 51.6 bits (118), Expect = 2e-05
Identities = 28/82 (34%), Positives = 43/82 (52%), Gaps = 1/82 (1%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-R 463
G+G + I +A +GV V NAP N+ S E+T L+L + R + A A++ G W+ R
Sbjct: 71 GSGTNRIAKAAAAARGVLVTNAPNTNSRSVAEMTIGLLLAVVRRLCEADLAVREGNWEFR 130
Query: 464 ALYTGSELAGKTLAILALAGSA 529
G EL +TL ++ A
Sbjct: 131 YTGKGMELHTRTLGLVGFGAIA 152
>UniRef50_Q3KAR6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=3;
Gammaproteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Pseudomonas fluorescens
(strain PfO-1)
Length = 322
Score = 51.6 bits (118), Expect = 2e-05
Identities = 26/77 (33%), Positives = 40/77 (51%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
GAG + +D+ +A +G+ V N G NA S + ++L L R + A++ G W +
Sbjct: 75 GAGYEQVDLQAASDRGLTVTNGAGVNASSVADHAMAMLLALVRDIPRCDGAVRRGEWPKI 134
Query: 467 LYTGSELAGKTLAILAL 517
+ LAGK L IL L
Sbjct: 135 M--RPSLAGKRLGILGL 149
>UniRef50_Q44NM9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=1;
Chlorobium limicola DSM 245|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Chlorobium limicola DSM 245
Length = 305
Score = 51.6 bits (118), Expect = 2e-05
Identities = 27/79 (34%), Positives = 42/79 (53%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R G G+D++D+D A +KG+ V N P S ELT + L L R V A +K G W
Sbjct: 76 RVGVGMDSVDLDYAKQKGIVVTNTPDGPTRSVAELTIAMTLALLRKVPQAHMNIKQGVWK 135
Query: 461 RALYTGSELAGKTLAILAL 517
+ + G+ + K + ++ L
Sbjct: 136 KEI--GNLMYEKKVGLIGL 152
>UniRef50_A3K878 Cluster: 2-hydroxyacid dehydrogenase; n=1;
Sagittula stellata E-37|Rep: 2-hydroxyacid dehydrogenase
- Sagittula stellata E-37
Length = 314
Score = 51.6 bits (118), Expect = 2e-05
Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 2/79 (2%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR- 463
G G D +DV++A + GV V N P E+T LML LA V + ++ GRW+
Sbjct: 75 GVGYDAVDVEAAKEHGVRVTNTPDVLNDCVAEVTLALMLALAHRVPESHAYVRDGRWETE 134
Query: 464 -ALYTGSELAGKTLAILAL 517
A+ +EL G T+ I+ L
Sbjct: 135 GAMPLTAELTGATVGIIGL 153
>UniRef50_A2F8V0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, putative; n=3; Trichomonas vaginalis
G3|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
putative - Trichomonas vaginalis G3
Length = 396
Score = 51.6 bits (118), Expect = 2e-05
Identities = 30/78 (38%), Positives = 43/78 (55%), Gaps = 1/78 (1%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAGAGV+ IDV++A KGV V N PG N + EL ++ R + + L+ G W
Sbjct: 69 RAGAGVNTIDVNAASAKGVLVCNTPGMNNDAVAELAFGHIVCCDRCITTNTAHLRNGEWR 128
Query: 461 RALYTGSE-LAGKTLAIL 511
+ L+ E L +TL I+
Sbjct: 129 KKLFLTCEGLRDRTLGIV 146
>UniRef50_Q7UQC8 Cluster: Probable 2-hydroxyacid dehydrogenase; n=1;
Pirellula sp.|Rep: Probable 2-hydroxyacid dehydrogenase
- Rhodopirellula baltica
Length = 406
Score = 51.2 bits (117), Expect = 2e-05
Identities = 27/78 (34%), Positives = 43/78 (55%), Gaps = 3/78 (3%)
Frame = +2
Query: 293 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDR 463
G +NIDVD+A +GV V N P + +L +L+ +RHV+PA ++ G W+
Sbjct: 163 GFNNIDVDAAKTRGVVVGNTPDVLTDATADLAVSLLFAASRHVLPAGNQVREGEWKTWEP 222
Query: 464 ALYTGSELAGKTLAILAL 517
+ G E + KTL I+ +
Sbjct: 223 TGWLGVEPSDKTLGIVGM 240
>UniRef50_Q5FUW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=55;
Bacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Gluconobacter oxydans (Gluconobacter suboxydans)
Length = 416
Score = 51.2 bits (117), Expect = 2e-05
Identities = 25/73 (34%), Positives = 40/73 (54%)
Frame = +2
Query: 293 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY 472
G + +D+++A G+ V NAP +N S EL +++L R + S A G WD++
Sbjct: 86 GTNQVDLNAARMLGIPVFNAPFSNTRSVAELVMGEIVMLLRRIPSRSEACHKGGWDKSAT 145
Query: 473 TGSELAGKTLAIL 511
E+ GKTL I+
Sbjct: 146 NAWEVRGKTLGIV 158
>UniRef50_A1W9A3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Acidovorax sp.
JS42|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Acidovorax sp. (strain JS42)
Length = 339
Score = 51.2 bits (117), Expect = 2e-05
Identities = 26/76 (34%), Positives = 41/76 (53%)
Frame = +2
Query: 290 AGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL 469
AG D+ID+++ K+G+ V + P + S E L+L + RH+ A + G +
Sbjct: 80 AGFDHIDLEACRKRGIAVCHVPDYGSASVAEHAFALLLGVTRHLTQAHERARQGSFAYRG 139
Query: 470 YTGSELAGKTLAILAL 517
TG EL G+TL I+ L
Sbjct: 140 LTGFELEGRTLGIVGL 155
Score = 34.3 bits (75), Expect = 2.7
Identities = 14/30 (46%), Positives = 21/30 (70%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSA 597
+GLGR+GR VA FGM+++ +DP +A
Sbjct: 153 VGLGRIGRHVARIAVGFGMDVLAYDPAFAA 182
>UniRef50_A4EAR0 Cluster: Putative uncharacterized protein; n=1;
Collinsella aerofaciens ATCC 25986|Rep: Putative
uncharacterized protein - Collinsella aerofaciens ATCC
25986
Length = 387
Score = 50.8 bits (116), Expect = 3e-05
Identities = 29/81 (35%), Positives = 44/81 (54%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R GAGV+NI V+ KKGV V N+PGAN+ + EL ++++ +R VV + ++ D
Sbjct: 55 RCGAGVNNIPVEEYAKKGVVVFNSPGANSNAVKELVLGMLVLSSRGVVQSMNWVRDNADD 114
Query: 461 RALYTGSELAGKTLAILALAG 523
+ +E A K L G
Sbjct: 115 PEIQVDAEKAKKAFVGRELKG 135
Score = 35.9 bits (79), Expect = 0.88
Identities = 20/57 (35%), Positives = 28/57 (49%), Gaps = 3/57 (5%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKME---LEDIWPLADYIT 669
+GLG VG VA GM++ G+DPF+S + LED+ DY+T
Sbjct: 141 IGLGNVGSKVANACVDLGMDVYGYDPFISVEHAWVLSREVQRVGTLEDLCRGCDYLT 197
>UniRef50_A0RUD3 Cluster: 2 lactate dehydrogenase; n=2;
Thermoprotei|Rep: 2 lactate dehydrogenase - Cenarchaeum
symbiosum
Length = 348
Score = 50.8 bits (116), Expect = 3e-05
Identities = 30/85 (35%), Positives = 42/85 (49%), Gaps = 4/85 (4%)
Frame = +2
Query: 293 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL- 469
G D+IDV A +G+ V P + +LT LML L R V ++AGRW +
Sbjct: 111 GYDHIDVAHARGRGITVGYTPDVLTDATADLTMALMLDLLRRVTEGDRIIRAGRWRQIYG 170
Query: 470 ---YTGSELAGKTLAILALAGSADR 535
Y G+++ GKTL IL + R
Sbjct: 171 ADDYLGTDVGGKTLGILGMGRIGSR 195
>UniRef50_Q8F5N8 Cluster: Phosphoglycerate dehydrogenase; n=4;
Leptospira|Rep: Phosphoglycerate dehydrogenase -
Leptospira interrogans
Length = 332
Score = 50.4 bits (115), Expect = 4e-05
Identities = 26/79 (32%), Positives = 41/79 (51%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R G G+D++ ++ ++G+ V P A ++ ELT LM+ R V A LK G W
Sbjct: 77 RVGIGLDSVPLNLCKERGIAVAYTPDAVTMAVAELTIGLMISSTRKVFLAHQELKTGGWS 136
Query: 461 RALYTGSELAGKTLAILAL 517
R +TG L T+ I+ +
Sbjct: 137 R--FTGKRLGESTIGIVGV 153
>UniRef50_Q896Z8 Cluster: 2-hydroxyacid dehydrogenase; n=4;
Clostridium|Rep: 2-hydroxyacid dehydrogenase -
Clostridium tetani
Length = 357
Score = 50.4 bits (115), Expect = 4e-05
Identities = 26/76 (34%), Positives = 46/76 (60%)
Frame = +2
Query: 284 AGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR 463
A G+D+I++++ K + V N+ G + S ELT L+L L R++VP + ++ G +
Sbjct: 117 AFTGIDHINMETCRKNNIMVCNSAGYSTSSVVELTFGLILSLLRNIVPLNDEVRNGNTKQ 176
Query: 464 ALYTGSELAGKTLAIL 511
Y+ +LAGKTL ++
Sbjct: 177 G-YSQYDLAGKTLGVI 191
>UniRef50_Q72KT6 Cluster: Glycerate dehydrogenase/glyoxylate
reductase; n=2; Thermus thermophilus|Rep: Glycerate
dehydrogenase/glyoxylate reductase - Thermus
thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Length = 338
Score = 50.4 bits (115), Expect = 4e-05
Identities = 25/78 (32%), Positives = 44/78 (56%), Gaps = 3/78 (3%)
Frame = +2
Query: 293 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAG---RWDR 463
GVD++D+++A ++G+ V + PG + +LT L+L +AR VV + + G W
Sbjct: 102 GVDHVDLEAARERGIRVTHTPGVLTEATADLTLALLLAVARRVVEGAAYARDGLWRAWHP 161
Query: 464 ALYTGSELAGKTLAILAL 517
L G +L G TL ++ +
Sbjct: 162 ELLLGLDLQGLTLGLVGM 179
>UniRef50_Q2S4U0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding domain protein; n=2; cellular
organisms|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding domain protein - Salinibacter
ruber (strain DSM 13855)
Length = 321
Score = 50.4 bits (115), Expect = 4e-05
Identities = 28/78 (35%), Positives = 41/78 (52%), Gaps = 3/78 (3%)
Frame = +2
Query: 293 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAG---RWDR 463
GVDNID+++A V V + PG + + L+L ARHV A ++ G RW+
Sbjct: 78 GVDNIDLEAAEAHDVAVTHTPGVLTDATADQAWALLLAAARHVPAADRYVRDGRFERWET 137
Query: 464 ALYTGSELAGKTLAILAL 517
G ELA KT+ I+ +
Sbjct: 138 THLMGMELARKTIGIVGM 155
>UniRef50_Q11UL6 Cluster: Phosphoglycerate dehydrogenase; n=1;
Cytophaga hutchinsonii ATCC 33406|Rep: Phosphoglycerate
dehydrogenase - Cytophaga hutchinsonii (strain ATCC
33406 / NCIMB 9469)
Length = 314
Score = 50.4 bits (115), Expect = 4e-05
Identities = 27/77 (35%), Positives = 42/77 (54%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAGAGVDNID + +K + + +A N ++ E T L+L L ++V + T +K W
Sbjct: 72 RAGAGVDNIDKEYLKEKNIALFHASEGNRVAVGEHTLGLILALINNIVRSDTEVKDAIWL 131
Query: 461 RALYTGSELAGKTLAIL 511
R G EL T+ ++
Sbjct: 132 REENRGYELESLTVGLI 148
Score = 39.9 bits (89), Expect = 0.054
Identities = 22/63 (34%), Positives = 35/63 (55%)
Frame = +3
Query: 87 LIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDQA*S 266
LIVD V +LL+ IA K SKE + +P ++ LV+RS +V K+++D
Sbjct: 7 LIVDDVDTALFQLLDKAAIAYDYKPDWSKETCIEALPAYEGLVIRSKFRVDKKIIDSCTK 66
Query: 267 LRW 275
L++
Sbjct: 67 LQF 69
>UniRef50_A7IJ69 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=2; Rhizobiales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Xanthobacter sp. (strain Py2)
Length = 359
Score = 50.4 bits (115), Expect = 4e-05
Identities = 29/77 (37%), Positives = 42/77 (54%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R G G D +DVD+A G V A GAN + + T LML + R + + A+ G W
Sbjct: 110 RRGVGYDRVDVDAARDLGRVVTIAAGANDPAVADHTIALMLAVLRRLKASQAAIARGDW- 168
Query: 461 RALYTGSELAGKTLAIL 511
R L G++L GKT+ ++
Sbjct: 169 RVL-VGADLTGKTVGLI 184
>UniRef50_A0LN07 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Syntrophobacter
fumaroxidans MPOB|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 317
Score = 50.4 bits (115), Expect = 4e-05
Identities = 29/78 (37%), Positives = 42/78 (53%), Gaps = 1/78 (1%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW- 457
R G G+D ID+ A ++GV V+ P AN S E + ++LA+ + AL+ G W
Sbjct: 72 RHGVGLDAIDLRCAKERGVKVVFTPTANTESVAEHFVGMAIMLAKMIRTGDIALRTGDWA 131
Query: 458 DRALYTGSELAGKTLAIL 511
R G+EL GK L +L
Sbjct: 132 ARNRLIGTELHGKALGVL 149
>UniRef50_A4S3N1 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 380
Score = 50.4 bits (115), Expect = 4e-05
Identities = 23/74 (31%), Positives = 40/74 (54%)
Frame = +2
Query: 290 AGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL 469
AG DN+D + A ++G+ V+ P + LS E +M+ L RH+ + L+ G +
Sbjct: 111 AGFDNVDCERARERGISVLRVPAYDPLSISEHAVAMMMSLNRHLCASRDRLRMGNFTLDG 170
Query: 470 YTGSELAGKTLAIL 511
GS + GKT+ ++
Sbjct: 171 LVGSSMRGKTVGVV 184
>UniRef50_Q5KFZ5 Cluster: Phosphoglycerate dehydrogenase, putative;
n=2; Filobasidiella neoformans|Rep: Phosphoglycerate
dehydrogenase, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 339
Score = 50.4 bits (115), Expect = 4e-05
Identities = 22/57 (38%), Positives = 32/57 (56%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAG 451
R G GVDN+ + + +G+ V N PG+NA + EL LML + R VV ++ G
Sbjct: 84 RNGTGVDNVPLPTCLSRGIAVTNIPGSNAFAVAELAIALMLTVLRRVVEVDKRIRGG 140
>UniRef50_Q7WEA3 Cluster: Phosphoglycerate dehydrogenase; n=1;
Bordetella bronchiseptica|Rep: Phosphoglycerate
dehydrogenase - Bordetella bronchiseptica (Alcaligenes
bronchisepticus)
Length = 329
Score = 50.0 bits (114), Expect = 5e-05
Identities = 31/81 (38%), Positives = 40/81 (49%), Gaps = 4/81 (4%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW--- 457
G G D I V A G+ V+ P AN S E LMLV AR V A A + G W
Sbjct: 70 GTGTDKIAVAHADALGIPVVYTPQANVRSVAEHALMLMLVTARQAVQADAATRKGHWGFK 129
Query: 458 -DRALYTGSELAGKTLAILAL 517
++ +Y+ L GKTL ++ L
Sbjct: 130 YEQPMYS---LYGKTLGVIGL 147
>UniRef50_Q74CK1 Cluster: Glycerate dehydrogenase; n=12;
Bacteria|Rep: Glycerate dehydrogenase - Geobacter
sulfurreducens
Length = 327
Score = 50.0 bits (114), Expect = 5e-05
Identities = 24/58 (41%), Positives = 36/58 (62%)
Frame = +2
Query: 293 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
G +N+DV++AGK+G+ V N P + S + T L+L LA HV +A+KA W R+
Sbjct: 79 GYNNVDVEAAGKRGIPVANIPAYSTESVVQTTFALLLELAVHVGIHDSAVKAREWVRS 136
>UniRef50_A5V6T9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Sphingomonas wittichii
RW1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Sphingomonas wittichii RW1
Length = 317
Score = 50.0 bits (114), Expect = 5e-05
Identities = 26/78 (33%), Positives = 42/78 (53%), Gaps = 3/78 (3%)
Frame = +2
Query: 293 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD---R 463
G+D+ID+D+ +G+ + N PG + + + L+L R + A+ L+ GRW
Sbjct: 78 GLDHIDLDAVRARGLPMFNTPGILSNAVADQAMLLLLAATRRMAEATALLREGRWTDLWS 137
Query: 464 ALYTGSELAGKTLAILAL 517
+ G ELAG+TL I L
Sbjct: 138 SHILGVELAGRTLGIYGL 155
>UniRef50_A1AQ02 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=3; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Pelobacter propionicus (strain DSM 2379)
Length = 318
Score = 50.0 bits (114), Expect = 5e-05
Identities = 29/80 (36%), Positives = 44/80 (55%), Gaps = 4/80 (5%)
Frame = +2
Query: 284 AGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD- 460
AG G +NID+ +A +G+GV N P + + +L T ML L+ +V T L+ G D
Sbjct: 75 AGTGYNNIDIAAARSRGIGVCNVPSYSTDAVAQLAITFMLNLSASLVQQQTMLRRGNLDN 134
Query: 461 --RALYTGS-ELAGKTLAIL 511
++L EL GKTL ++
Sbjct: 135 FQKSLQLPHFELNGKTLGVI 154
>UniRef50_Q9HK29 Cluster: 2-hydroxyacid dehydrogenase related
protein; n=4; Thermoplasmatales|Rep: 2-hydroxyacid
dehydrogenase related protein - Thermoplasma acidophilum
Length = 309
Score = 50.0 bits (114), Expect = 5e-05
Identities = 29/84 (34%), Positives = 46/84 (54%)
Frame = +2
Query: 284 AGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR 463
A G DN+D+++ K G+ V N P A+A S E +++L L + +++GRW R
Sbjct: 68 ASIGYDNVDMNAMKKNGIMVSNIPTASADSVAEHALSMVLSLIKDQRFLDAEIRSGRWPR 127
Query: 464 ALYTGSELAGKTLAILALAGSADR 535
+ S+L GKT I+ + GS R
Sbjct: 128 -ITRSSDLMGKTFGIVGM-GSIGR 149
>UniRef50_Q89QF5 Cluster: Blr3173 protein; n=3; Bradyrhizobium|Rep:
Blr3173 protein - Bradyrhizobium japonicum
Length = 360
Score = 49.6 bits (113), Expect = 7e-05
Identities = 28/84 (33%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR-WDR 463
GAG D +DV++ GV V+N G NA S E +ML L++ ++ + L+ R +R
Sbjct: 97 GAGFDPVDVEACTDAGVLVVNQSGGNAHSVAEHALAMMLTLSKRIIQSDRRLRRERDVNR 156
Query: 464 ALYTGSELAGKTLAILALAGSADR 535
G+E+ KT+ I+ L R
Sbjct: 157 NDLVGNEVEHKTVGIIGLGNVGRR 180
Score = 39.9 bits (89), Expect = 0.054
Identities = 18/55 (32%), Positives = 35/55 (63%), Gaps = 1/55 (1%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAF-GMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+GLG VGR +A GM ++ +DP+++A+ A+ K+EL+++ AD+++
Sbjct: 172 IGLGNVGRRIAALCNGLLGMKVLAYDPYLTAEVMAERGGEKVELDELLRRADFVS 226
>UniRef50_Q89J71 Cluster: 2-hydroxyacid dehydrogenase; n=8;
Bradyrhizobiaceae|Rep: 2-hydroxyacid dehydrogenase -
Bradyrhizobium japonicum
Length = 317
Score = 49.6 bits (113), Expect = 7e-05
Identities = 20/57 (35%), Positives = 34/57 (59%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW 457
G G D +D+ +A + + V ++PGANA S ++ TLML R ++ A +++G W
Sbjct: 74 GTGYDGVDLKAAAARDIAVGHSPGANAASVADIAMTLMLATTRRILVADQYVRSGDW 130
>UniRef50_Q6A5K9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, putative D-3- phosphoglycerate
dehydrogenase; n=1; Propionibacterium acnes|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase, putative
D-3- phosphoglycerate dehydrogenase - Propionibacterium
acnes
Length = 321
Score = 49.6 bits (113), Expect = 7e-05
Identities = 29/82 (35%), Positives = 44/82 (53%), Gaps = 3/82 (3%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAG--- 451
+ AG +NID+D+A + GV V + PG + +L TL+L + R A ++AG
Sbjct: 70 QCAAGFNNIDLDAAKQAGVVVTSTPGVLHEATADLAFTLLLEVTRRTGEAERWVRAGRAW 129
Query: 452 RWDRALYTGSELAGKTLAILAL 517
R+D G+ L G TL I+ L
Sbjct: 130 RYDHTFMLGAGLQGATLGIVGL 151
>UniRef50_O34815 Cluster: YoaD; n=2; Bacillus|Rep: YoaD - Bacillus
subtilis
Length = 344
Score = 49.6 bits (113), Expect = 7e-05
Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 6/84 (7%)
Frame = +2
Query: 302 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR------ 463
N+DV +A K+G+ V PG NA + E+ ++ RH ++ LK G WD
Sbjct: 94 NVDVAAASKRGIPVFYTPGRNAQAVAEMFIGNVISFLRHTSASNQWLKDGEWDSDYLQAY 153
Query: 464 ALYTGSELAGKTLAILALAGSADR 535
+ G+EL GKT+ ++ R
Sbjct: 154 VKFKGNELTGKTVGMIGFGAVGQR 177
>UniRef50_Q27SN5 Cluster: Beta xylosidase-like protein; n=1;
Acanthamoeba castellanii|Rep: Beta xylosidase-like
protein - Acanthamoeba castellanii (Amoeba)
Length = 222
Score = 49.6 bits (113), Expect = 7e-05
Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 5/82 (6%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR- 463
GAG D +DV +A ++ + V N PGA + ++ L+L R A L+ G W+R
Sbjct: 52 GAGYDTVDVKAATERNIWVCNTPGAVTNATADVALYLLLAACRRATEAERFLRDGSWERQ 111
Query: 464 ----ALYTGSELAGKTLAILAL 517
+ G+ GKTL I+ +
Sbjct: 112 GSDILAFWGNNPEGKTLGIIGM 133
>UniRef50_UPI00015BD3AA Cluster: UPI00015BD3AA related cluster; n=1;
unknown|Rep: UPI00015BD3AA UniRef100 entry - unknown
Length = 332
Score = 49.2 bits (112), Expect = 9e-05
Identities = 28/73 (38%), Positives = 37/73 (50%)
Frame = +2
Query: 293 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY 472
G D+IDV A KG+ V N P S E LML LAR + ++ G + +
Sbjct: 75 GFDHIDVAYANSKGITVCNVPSYGEESVSEYAIMLMLALARKLRETIDNVEKGVYKTSNL 134
Query: 473 TGSELAGKTLAIL 511
G ELAGKTL ++
Sbjct: 135 RGIELAGKTLGVI 147
>UniRef50_Q1GJ08 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=24; Rhodobacterales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Silicibacter sp. (strain TM1040)
Length = 322
Score = 49.2 bits (112), Expect = 9e-05
Identities = 27/85 (31%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-- 460
G G ++ID ++A GV V N PGA + ++ TLML+ AR +++G+W
Sbjct: 81 GVGFNHIDAEAARAAGVEVTNTPGAVTDATADIALTLMLMTARRAGEGERLVRSGQWQGW 140
Query: 461 -RALYTGSELAGKTLAILALAGSAD 532
G L+GK L ++ L D
Sbjct: 141 HPTQMLGLHLSGKRLGVVGLGRIGD 165
>UniRef50_A6CRV0 Cluster: 2-hydroxyacid dehydrogenase; n=15;
Bacillales|Rep: 2-hydroxyacid dehydrogenase - Bacillus
sp. SG-1
Length = 351
Score = 49.2 bits (112), Expect = 9e-05
Identities = 25/78 (32%), Positives = 42/78 (53%), Gaps = 3/78 (3%)
Frame = +2
Query: 293 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDR 463
G DNID+ +A +K V V N P + +LT LM+ AR ++ A ++ G+ W
Sbjct: 104 GFDNIDLKAANEKDVAVCNTPDVLTDTTADLTFGLMMAAARRLIEADKYVREGKWKSWSP 163
Query: 464 ALYTGSELAGKTLAILAL 517
L G+++ KT+ I+ +
Sbjct: 164 LLMAGTDIHHKTVGIIGM 181
>UniRef50_A3UGW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Oceanicaulis alexandrii HTCC2633
Length = 407
Score = 49.2 bits (112), Expect = 9e-05
Identities = 24/73 (32%), Positives = 40/73 (54%)
Frame = +2
Query: 293 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY 472
G + +D+ +A ++GV V NAP AN S ELT +++L R + A++ G W +
Sbjct: 81 GTNQVDLVAAAERGVPVFNAPFANTRSVAELTMASVIMLMRRIPEKMFAIQRGEWLKTAD 140
Query: 473 TGSELAGKTLAIL 511
+E+ K L I+
Sbjct: 141 GANEVRKKKLGII 153
>UniRef50_Q6F7L0 Cluster: Glycerate dehydrogenase; n=3;
Gammaproteobacteria|Rep: Glycerate dehydrogenase -
Acinetobacter sp. (strain ADP1)
Length = 318
Score = 48.8 bits (111), Expect = 1e-04
Identities = 29/82 (35%), Positives = 43/82 (52%), Gaps = 6/82 (7%)
Frame = +2
Query: 284 AGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR 463
+ G +N+D+ +A +G+ V N G S + T TLML LA ++ A+ GRW +
Sbjct: 73 SATGTNNVDLRAAKAQGIVVCNCQGYGTASVAQHTLTLMLALATSLLRYDHAVAQGRWQQ 132
Query: 464 AL------YTGSELAGKTLAIL 511
A Y EL+GKTL I+
Sbjct: 133 ASQFCFLDYPIIELSGKTLGIV 154
>UniRef50_Q63VJ5 Cluster: D-3-phosphoglycerate dehydrogenase; n=8;
Burkholderiaceae|Rep: D-3-phosphoglycerate dehydrogenase
- Burkholderia pseudomallei (Pseudomonas pseudomallei)
Length = 424
Score = 48.8 bits (111), Expect = 1e-04
Identities = 25/73 (34%), Positives = 35/73 (47%)
Frame = +2
Query: 293 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY 472
G +D+ +A G+ V NAP +N S EL ++L R V S AG W +
Sbjct: 98 GTSQVDLPAAAHHGIPVFNAPFSNTRSVAELVIAEAILLLRRVPEKSVLAHAGEWAKGAG 157
Query: 473 TGSELAGKTLAIL 511
E GKT+AI+
Sbjct: 158 GSFEARGKTIAIV 170
>UniRef50_Q7X388 Cluster: Phosphoglycerate dehydrogenase; n=3;
Escherichia coli|Rep: Phosphoglycerate dehydrogenase -
Escherichia coli
Length = 306
Score = 48.8 bits (111), Expect = 1e-04
Identities = 29/77 (37%), Positives = 42/77 (54%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
G G+DNIDVD A K + V A AN++S E+T +ML +R V + + G+ R
Sbjct: 78 GVGLDNIDVDYANSKDIVVHKALNANSISVAEMTILMMLSSSRKYVEIESQARNGKDIRL 137
Query: 467 LYTGSELAGKTLAILAL 517
+ G EL K L ++ L
Sbjct: 138 V--GYELYQKNLGLIGL 152
>UniRef50_Q03U10 Cluster: 2-hydroxyacid dehydrogenase; n=1;
Lactobacillus brevis ATCC 367|Rep: 2-hydroxyacid
dehydrogenase - Lactobacillus brevis (strain ATCC 367 /
JCM 1170)
Length = 330
Score = 48.8 bits (111), Expect = 1e-04
Identities = 30/87 (34%), Positives = 43/87 (49%), Gaps = 2/87 (2%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPG-ANALSACELTCTLMLVLARHVVPASTALKAGRW 457
R G G +N+DV +A G V P S E +L + R VPA+ +AGR+
Sbjct: 79 RHGIGFNNVDVKAAKAHGTLVTIVPQLVERDSVAENELVNLLTMVRRTVPAAERERAGRY 138
Query: 458 -DRALYTGSELAGKTLAILALAGSADR 535
DRA + G+EL+GKT ++ R
Sbjct: 139 EDRAEFMGNELSGKTFGVIGCGNIGSR 165
>UniRef50_A7CR80 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Opitutaceae bacterium
TAV2|Rep: D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Opitutaceae bacterium TAV2
Length = 355
Score = 48.8 bits (111), Expect = 1e-04
Identities = 28/82 (34%), Positives = 41/82 (50%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
G GVDN+D + + G+ + N PG ++ ++ LAR +KAG W ++
Sbjct: 121 GVGVDNVDFAACQRLGLPISNTPGMFGREVADVAVGYVIALARQTFAIDRTVKAGGWIKS 180
Query: 467 LYTGSELAGKTLAILALAGSAD 532
G LAGKT +ALAG D
Sbjct: 181 --AGISLAGKT---VALAGFGD 197
>UniRef50_A5Z3X2 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 387
Score = 48.8 bits (111), Expect = 1e-04
Identities = 24/48 (50%), Positives = 30/48 (62%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVV 424
RAGAGV+NI +D KGV V N PGANA EL ML+ +R ++
Sbjct: 55 RAGAGVNNIPLDKCADKGVVVFNTPGANANGVKELVLCGMLLASRDII 102
Score = 37.1 bits (82), Expect = 0.38
Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 4/58 (6%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQF----HCTKMELEDIWPLADYIT 669
+GLG +GR VA + GM + G DPF+S + H K E+I+ D+IT
Sbjct: 141 IGLGAIGRLVANAAESMGMEVYGNDPFISVEGALSLKRDVHLVKTR-EEIFKECDFIT 197
>UniRef50_A5N5A9 Cluster: SerA; n=1; Clostridium kluyveri DSM
555|Rep: SerA - Clostridium kluyveri DSM 555
Length = 320
Score = 48.8 bits (111), Expect = 1e-04
Identities = 25/79 (31%), Positives = 41/79 (51%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R G GV+N+D+ +A + + + NAP +N + E T L++ LA+ L+ G +
Sbjct: 70 RFGVGVNNVDIKTASELSIQITNAPESNKNTVAEYTMGLIIALAKKFFLYDRGLRKGNFK 129
Query: 461 RALYTGSELAGKTLAILAL 517
G +L GK L I+ L
Sbjct: 130 VRDILGIDLEGKVLGIVGL 148
>UniRef50_A0ZEB8 Cluster: Predicted dehydrogenase; n=6;
Cyanobacteria|Rep: Predicted dehydrogenase - Nodularia
spumigena CCY 9414
Length = 341
Score = 48.8 bits (111), Expect = 1e-04
Identities = 31/85 (36%), Positives = 45/85 (52%), Gaps = 3/85 (3%)
Frame = +2
Query: 284 AGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW-D 460
+G G D ID+ A K GV V+N PG + + E T ++L LA+ + + +K G +
Sbjct: 85 SGFGTDAIDISVATKHGVVVVNNPGLSTTAVAEHTICMILALAKKLTFLNQCVKTGNYLI 144
Query: 461 RALYTGSELAGKTLAILALA--GSA 529
R +L GKTL I+ L GSA
Sbjct: 145 RNQVQPMQLEGKTLGIVGLGRIGSA 169
>UniRef50_Q125T3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Polaromonas sp.
JS666|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Polaromonas sp. (strain
JS666 / ATCC BAA-500)
Length = 309
Score = 48.4 bits (110), Expect = 2e-04
Identities = 28/78 (35%), Positives = 40/78 (51%), Gaps = 1/78 (1%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW-DR 463
G G D I V A +G+ V + PG + CEL L+L L R + + ++ GRW D
Sbjct: 69 GVGYDGIPVAYAQARGIAVTHTPGVLDDAVCELGVGLLLGLLRDIPASDRFVRDGRWSDS 128
Query: 464 ALYTGSELAGKTLAILAL 517
A + LAGK + I+ L
Sbjct: 129 AYPLTTSLAGKAVGIVGL 146
>UniRef50_A1HQU2 Cluster: Glyoxylate reductase; n=1; Thermosinus
carboxydivorans Nor1|Rep: Glyoxylate reductase -
Thermosinus carboxydivorans Nor1
Length = 324
Score = 48.4 bits (110), Expect = 2e-04
Identities = 25/81 (30%), Positives = 43/81 (53%), Gaps = 2/81 (2%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW- 457
+A G DN+D+ + ++G+ N PG + +LT L+L AR + + +GRW
Sbjct: 74 QASVGYDNVDIAACTRRGIPFGNTPGVLVEATADLTFGLLLCAARRIHEGWNQVASGRWL 133
Query: 458 -DRALYTGSELAGKTLAILAL 517
+ + G +L GKTL I+ +
Sbjct: 134 NNHDVPFGIDLYGKTLGIVGM 154
>UniRef50_A0GDF1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Burkholderia
phytofirmans PsJN|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Burkholderia phytofirmans
PsJN
Length = 274
Score = 48.4 bits (110), Expect = 2e-04
Identities = 27/88 (30%), Positives = 46/88 (52%), Gaps = 6/88 (6%)
Frame = +2
Query: 290 AGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA- 466
AGV+++D ++ K+G+G++ PG + +S E LML L R+++P + AG W +
Sbjct: 37 AGVNHLDTETCRKRGIGIVACPGYSTISVPEHAFALMLALRRNLMPYWHDVYAGGWSGSP 96
Query: 467 -----LYTGSELAGKTLAILALAGSADR 535
L+ +L G TL I+ R
Sbjct: 97 TFYAELHPIQDLHGSTLGIVGAGHGGKR 124
>UniRef50_Q27SS3 Cluster: Glycerate dehydrogenase-like protein; n=2;
Eukaryota|Rep: Glycerate dehydrogenase-like protein -
Trimastix pyriformis
Length = 232
Score = 48.4 bits (110), Expect = 2e-04
Identities = 28/78 (35%), Positives = 42/78 (53%), Gaps = 3/78 (3%)
Frame = +2
Query: 293 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAG---RWDR 463
G +NID+ +A ++ V V N P A + +LT L+L +AR +V ++AG W
Sbjct: 76 GYNNIDLTAANERHVVVTNTPHCLAEATADLTMGLLLAVARRLVEGDGLVRAGLFKGWAP 135
Query: 464 ALYTGSELAGKTLAILAL 517
G +L GKTL I+ L
Sbjct: 136 EFLLGMDLHGKTLGIIGL 153
>UniRef50_Q5V1E2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Haloarcula marismortui|Rep: D-3-phosphoglycerate
dehydrogenase - Haloarcula marismortui (Halobacterium
marismortui)
Length = 323
Score = 48.4 bits (110), Expect = 2e-04
Identities = 30/87 (34%), Positives = 42/87 (48%), Gaps = 1/87 (1%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
RAG G+DNI V +A GV V+N P + T LML R + ++K G W
Sbjct: 74 RAGIGMDNIAVRAAVAAGVTVVNVPDYSVEEVSTHTFALMLACLRRIPTFDRSVKRGEWK 133
Query: 461 RAL-YTGSELAGKTLAILALAGSADRW 538
A+ LAG T+ ++A A R+
Sbjct: 134 WAVGQPIRRLAGSTVGLVAFGKLASRF 160
Score = 33.5 bits (73), Expect = 4.7
Identities = 20/56 (35%), Positives = 29/56 (51%)
Frame = +3
Query: 105 GAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDQA*SLR 272
G A +L+A T A E + + DAL+V + TQVT EV++ A SL+
Sbjct: 15 GETRAAVLDAVDATVETIAAKEPEAVARAVDGADALIVDAGTQVTAEVIEAADSLK 70
>UniRef50_Q11JF3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Mesorhizobium sp.
BNC1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Mesorhizobium sp. (strain BNC1)
Length = 312
Score = 48.0 bits (109), Expect = 2e-04
Identities = 24/77 (31%), Positives = 40/77 (51%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
G G + ID+++ +K + V N G NA S E L+L + R + A A+++G W+ A
Sbjct: 74 GVGYEKIDMEAVREKKIIVANNAGTNAFSVAEQALGLLLAVLRDIPAAERAVRSGIWEEA 133
Query: 467 LYTGSELAGKTLAILAL 517
Y + K + I+ L
Sbjct: 134 RYPRPLIFEKRVGIVGL 150
>UniRef50_A1W7V5 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Proteobacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Acidovorax sp. (strain JS42)
Length = 337
Score = 48.0 bits (109), Expect = 2e-04
Identities = 24/73 (32%), Positives = 37/73 (50%)
Frame = +2
Query: 293 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY 472
G D+ID+D G+ V N P + E L+L ++RH+V + + G + +
Sbjct: 74 GYDHIDLDYCRAHGIAVSNVPDYGDATVAEHAFALLLAVSRHIVTGAERTRRGDFSQHGL 133
Query: 473 TGSELAGKTLAIL 511
G EL GKTL +L
Sbjct: 134 RGFELRGKTLGVL 146
>UniRef50_A0JWH0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=14; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Arthrobacter sp. (strain FB24)
Length = 322
Score = 48.0 bits (109), Expect = 2e-04
Identities = 30/77 (38%), Positives = 43/77 (55%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
G +ID+ +A + G+ V+ G + +A ELT L+L LAR + L+ GRW
Sbjct: 79 GMANQSIDLRAAEELGI-VVCGTGGSPTAAPELTWGLLLALARSISFEDRNLREGRWQST 137
Query: 467 LYTGSELAGKTLAILAL 517
+ G ELAGKTL +L L
Sbjct: 138 V--GFELAGKTLGVLGL 152
Score = 41.1 bits (92), Expect = 0.024
Identities = 19/54 (35%), Positives = 34/54 (62%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
LGLG++GR VA AFGM++I + P ++ + AQ K+ E+++ +D ++
Sbjct: 150 LGLGKIGRRVAAYGQAFGMDVIAWSPNLTGEAAAQAGVRKVSKEELFRDSDVVS 203
>UniRef50_UPI0000DA2A77 Cluster: PREDICTED: similar to
D-3-phosphoglycerate dehydrogenase (3-PGDH); n=2; Rattus
norvegicus|Rep: PREDICTED: similar to
D-3-phosphoglycerate dehydrogenase (3-PGDH) - Rattus
norvegicus
Length = 155
Score = 47.6 bits (108), Expect = 3e-04
Identities = 28/78 (35%), Positives = 42/78 (53%)
Frame = +2
Query: 284 AGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR 463
AG G+DN+D+++A +K + V+N N+LS ELTC + L A P + + +
Sbjct: 71 AGTGMDNVDLEAAMRKSILVMNTSNGNSLSPVELTCGMNLCQAD--FPGNNFNERWQMGP 128
Query: 464 ALYTGSELAGKTLAILAL 517
G+ L GKTL L L
Sbjct: 129 EEVHGATLTGKTLGNLGL 146
Score = 36.3 bits (80), Expect = 0.67
Identities = 18/40 (45%), Positives = 23/40 (57%)
Frame = +1
Query: 424 PSFHCAEGWQVGPGSVHWQRARWQDPRHLGLGRVGR*VAT 543
P + E WQ+GP VH + +LGLGR+GR VAT
Sbjct: 116 PGNNFNERWQMGPEEVHGATLTGKTLGNLGLGRIGREVAT 155
Score = 35.9 bits (79), Expect = 0.88
Identities = 21/67 (31%), Positives = 39/67 (58%)
Frame = +3
Query: 72 DIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 251
+I VLI D + C ++L G+ ++KEEL+ E+ + + L ++SAT+VT + +
Sbjct: 5 NICKVLISDSLDPCCQKILQDGGLQN-----LNKEELITELQDCEGLTIQSATKVTADAV 59
Query: 252 DQA*SLR 272
+ A L+
Sbjct: 60 NAAQKLQ 66
>UniRef50_UPI0000D9FBAD Cluster: PREDICTED: similar to
3-phosphoglycerate dehydrogenase, partial; n=1; Macaca
mulatta|Rep: PREDICTED: similar to 3-phosphoglycerate
dehydrogenase, partial - Macaca mulatta
Length = 333
Score = 47.6 bits (108), Expect = 3e-04
Identities = 23/52 (44%), Positives = 33/52 (63%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 436
RAGAGVD ID+D+A K V V N PG NA + E+ L++ + R+ A++
Sbjct: 132 RAGAGVDTIDLDAASKHHVVVENTPGQNANAVAEMVFALLIAMKRNHFDATS 183
>UniRef50_UPI000023F60F Cluster: hypothetical protein FG08018.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG08018.1 - Gibberella zeae PH-1
Length = 901
Score = 47.6 bits (108), Expect = 3e-04
Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAG-RW 457
+ G G+D IDVD+ +G+ + N PG NA + EL TL AR V +G
Sbjct: 84 KQGVGLDKIDVDACASRGIKIFNTPGVNARAVAELVLTLATASARQVGSIIAKQSSGILV 143
Query: 458 DRALYTGSELAGKTLAILAL 517
+ +G L KT+ IL +
Sbjct: 144 PKEKCSGLILHEKTIGILGM 163
Score = 35.5 bits (78), Expect = 1.2
Identities = 20/56 (35%), Positives = 31/56 (55%), Gaps = 2/56 (3%)
Frame = +1
Query: 508 LGLGRVGR*VATRMY-AFGMNIIGFDPFVSADQCAQF-HCTKMELEDIWPLADYIT 669
LG+G +G+ VA AF N+I +DPF+ AD + H +E++ +D IT
Sbjct: 161 LGMGNIGKCVAKIFRGAFDANVIAYDPFLPADAWEEIPHKRATSVEEVLRSSDVIT 216
>UniRef50_A4FK85 Cluster: D-3-phosphoglycerate dehydrogenase,
putative; n=1; Saccharopolyspora erythraea NRRL
2338|Rep: D-3-phosphoglycerate dehydrogenase, putative -
Saccharopolyspora erythraea (strain NRRL 23338)
Length = 352
Score = 47.6 bits (108), Expect = 3e-04
Identities = 27/77 (35%), Positives = 39/77 (50%), Gaps = 4/77 (5%)
Frame = +2
Query: 293 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY 472
G N+D+ +A + GV V APG NA +A E L+L R + + LK+G W Y
Sbjct: 97 GPVNVDLQAATEAGVVVSYAPGRNAAAAAEFAVGLVLAALRRIPASDAELKSGNWRGDYY 156
Query: 473 ----TGSELAGKTLAIL 511
G EL G T+ ++
Sbjct: 157 AYENAGIELEGSTVGLV 173
Score = 33.9 bits (74), Expect = 3.6
Identities = 16/46 (34%), Positives = 26/46 (56%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDI 645
+G G +GR VA + AFG +++ DPFV + +ELE++
Sbjct: 173 VGYGAIGRIVARVLAAFGAHVLVADPFVKPEDATADGVELVELEEL 218
>UniRef50_A4RX85 Cluster: Predicted protein; n=3; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 454
Score = 47.6 bits (108), Expect = 3e-04
Identities = 33/101 (32%), Positives = 49/101 (48%), Gaps = 16/101 (15%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACEL-TCTLMLVLA------RHVVPASTA 439
R GAG +NI V + G+ V N PGANA + EL C+L+L +HV
Sbjct: 87 RCGAGTNNIPVKEMSELGIPVFNTPGANANAVKELVVCSLLLASRGIIEGNKHVNDVINV 146
Query: 440 LKAGRW---------DRALYTGSELAGKTLAILALAGSADR 535
+ G + D+A++ G+E+ GKTL ++ L R
Sbjct: 147 EENGDYAKISVRIEKDKAMFGGTEIEGKTLGVIGLGAIGSR 187
Score = 44.0 bits (99), Expect = 0.003
Identities = 22/58 (37%), Positives = 34/58 (58%), Gaps = 4/58 (6%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKM----ELEDIWPLADYIT 669
+GLG +G V GMN+IG+DP +S + + KM +L++++ LADYIT
Sbjct: 179 IGLGAIGSRVVNAALGLGMNVIGYDPVLSLEAAWRLPGDKMSRADDLDELFALADYIT 236
>UniRef50_Q4WMF4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=21; Pezizomycotina|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Aspergillus fumigatus (Sartorya fumigata)
Length = 343
Score = 47.6 bits (108), Expect = 3e-04
Identities = 30/76 (39%), Positives = 43/76 (56%), Gaps = 4/76 (5%)
Frame = +2
Query: 302 NIDVDSAGKKGVGVINA----PGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL 469
++D+ + +G+ V PG N S + T L+L LARHV A+KAG+W +L
Sbjct: 89 SLDLPALTARGIPVAGTVGRPPGVN--STVQHTWALILALARHVARDDAAVKAGKWQGSL 146
Query: 470 YTGSELAGKTLAILAL 517
G L+GKTLA+L L
Sbjct: 147 --GVNLSGKTLALLGL 160
>UniRef50_Q8TR50 Cluster: Glycerate dehydrogenase; n=2;
Methanosarcina|Rep: Glycerate dehydrogenase -
Methanosarcina acetivorans
Length = 319
Score = 47.6 bits (108), Expect = 3e-04
Identities = 27/73 (36%), Positives = 36/73 (49%)
Frame = +2
Query: 293 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY 472
G DN+D++ A GV V N P S E L L L R V A L+ G +D Y
Sbjct: 75 GFDNVDLEEATDHGVIVSNVPSYAFESVAEFVFALTLNLLRRVHLADMNLREGLFDWKYY 134
Query: 473 TGSELAGKTLAIL 511
G++L KT+ +L
Sbjct: 135 VGNQLMSKTIGVL 147
>UniRef50_Q986P2 Cluster: Phosphoglycerate dehydrogenase; n=14;
cellular organisms|Rep: Phosphoglycerate dehydrogenase -
Rhizobium loti (Mesorhizobium loti)
Length = 330
Score = 47.2 bits (107), Expect = 4e-04
Identities = 27/77 (35%), Positives = 39/77 (50%), Gaps = 4/77 (5%)
Frame = +2
Query: 293 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY 472
G NID+ +A G+ V+N PG NA + E T +L R + AL+ G W LY
Sbjct: 87 GPINIDMAAARAHGITVVNVPGRNATAVAEFTLGAILAETRLIRVGHEALRKGEWRGDLY 146
Query: 473 ----TGSELAGKTLAIL 511
TG EL+ T+ ++
Sbjct: 147 RADRTGRELSEMTVGVI 163
>UniRef50_Q11JH0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Mesorhizobium sp.
BNC1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Mesorhizobium sp. (strain BNC1)
Length = 342
Score = 47.2 bits (107), Expect = 4e-04
Identities = 28/80 (35%), Positives = 45/80 (56%), Gaps = 5/80 (6%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
G G+D ID++ A ++GV V G+NA + E T L+L R + A +++ G+W
Sbjct: 80 GIGIDKIDLEGAERQGVYVAITAGSNAGAVAEHTIMLILAALRRLALADQSMREGKW--- 136
Query: 467 LYTG-----SELAGKTLAIL 511
+YT +L+GKT+ IL
Sbjct: 137 IYTELRPLCRKLSGKTVGIL 156
>UniRef50_A4FIJ9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
D-3-phosphoglycerate dehydrogenase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 322
Score = 47.2 bits (107), Expect = 4e-04
Identities = 25/73 (34%), Positives = 37/73 (50%)
Frame = +2
Query: 293 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY 472
G D +D +A ++G+ V N PG NA + + T ML L RH ++ G W
Sbjct: 83 GFDGVDHVAAAERGIPVANLPGFNADAVADWTVGAMLHLLRHYAAGHRKVEQGGWGPEGL 142
Query: 473 TGSELAGKTLAIL 511
G +L+ T+AIL
Sbjct: 143 RGRDLSALTVAIL 155
Score = 33.1 bits (72), Expect = 6.2
Identities = 15/29 (51%), Positives = 18/29 (62%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVS 594
LG G +GR VA R+ FG I+ DPF S
Sbjct: 155 LGFGNIGRAVARRLDGFGAEIVVHDPFPS 183
>UniRef50_A4ARG6 Cluster: D-3-phosphoglycerate dehydrogenase; n=14;
Bacteroidetes|Rep: D-3-phosphoglycerate dehydrogenase -
Flavobacteriales bacterium HTCC2170
Length = 329
Score = 47.2 bits (107), Expect = 4e-04
Identities = 31/83 (37%), Positives = 43/83 (51%), Gaps = 6/83 (7%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLM------LVLARHVVPASTAL 442
R G G+DNIDV A +KG+ VIN P A++ S EL + L A +P
Sbjct: 83 RGGVGMDNIDVAYAKEKGLHVINTPAASSESVAELVFAHLFGGVRFLYDANRNMPLEGDS 142
Query: 443 KAGRWDRALYTGSELAGKTLAIL 511
K + ++ GSEL GKTL ++
Sbjct: 143 KFKQLKKSYAGGSELRGKTLGVI 165
Score = 36.7 bits (81), Expect = 0.51
Identities = 28/71 (39%), Positives = 40/71 (56%), Gaps = 3/71 (4%)
Frame = +3
Query: 69 VDIKSVLIVDGVGAKCAELLNAYG--IATTTKAKISKEELLMEIPNHDA-LVVRSATQVT 239
V+ +L DG+ L A G I+TTT A+ +E + E N A L+VRSATQV
Sbjct: 11 VNSMKILANDGISQTGINELEAAGFEISTTTVAQEQLKEFINE--NQIAGLLVRSATQVR 68
Query: 240 KEVLDQA*SLR 272
K+++D SL+
Sbjct: 69 KDIIDNCPSLK 79
>UniRef50_A1HM37 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=3; cellular organisms|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Thermosinus carboxydivorans Nor1
Length = 365
Score = 47.2 bits (107), Expect = 4e-04
Identities = 25/77 (32%), Positives = 41/77 (53%), Gaps = 3/77 (3%)
Frame = +2
Query: 290 AGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL 469
AG++N++V A K+G+ V N G NA + + T LML R++ A ++K G W +
Sbjct: 104 AGLENVNVKEATKRGILVFNIEGRNAEAVSDFTVGLMLAECRNIARAHYSIKNGGWRKEF 163
Query: 470 YTGS---ELAGKTLAIL 511
EL GK + ++
Sbjct: 164 SNSDWVPELKGKKVGLV 180
Score = 37.5 bits (83), Expect = 0.29
Identities = 16/54 (29%), Positives = 31/54 (57%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+G G +GR VA ++ FG+ + +DPFV + C ++ E ++ +D+I+
Sbjct: 180 VGFGYIGRLVAQKLSGFGVTRLVYDPFVDEETIRGAGCIPVDKETLFKESDFIS 233
>UniRef50_Q9TXJ5 Cluster: D-3-phosphoglycerate dehydrogenase-like
protein; n=10; cellular organisms|Rep:
D-3-phosphoglycerate dehydrogenase-like protein -
Leishmania major
Length = 511
Score = 47.2 bits (107), Expect = 4e-04
Identities = 24/73 (32%), Positives = 39/73 (53%)
Frame = +2
Query: 293 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY 472
G + +D+D A +GV V N+P AN S EL ++ L+R + S + G W++
Sbjct: 186 GTNQVDLDYATTRGVAVFNSPFANTRSVAELVIGEIISLSRKMTQRSEEVHRGVWNKTHV 245
Query: 473 TGSELAGKTLAIL 511
E+ GKT+ I+
Sbjct: 246 GCYEVRGKTVGIV 258
Score = 33.1 bits (72), Expect = 6.2
Identities = 21/59 (35%), Positives = 33/59 (55%), Gaps = 1/59 (1%)
Frame = +3
Query: 87 LIVDGVGAKCAELLNAYG-IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDQA 260
L+++GV ELL + G I + ++ LL +I + L +RS TQVT+ +LD A
Sbjct: 116 LLLEGVNPIAKELLESKGCIVEYIPNALPRDTLLEKIRDVHFLGIRSKTQVTQAILDAA 174
>UniRef50_Q6CDS0 Cluster: Similar to tr|O94020 Candida albicans
YNL274C homologue; n=2; Yarrowia lipolytica|Rep: Similar
to tr|O94020 Candida albicans YNL274C homologue -
Yarrowia lipolytica (Candida lipolytica)
Length = 351
Score = 47.2 bits (107), Expect = 4e-04
Identities = 25/79 (31%), Positives = 40/79 (50%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
GAG D IDV ++G+ V N S LM+ R+ + L+ G+W +
Sbjct: 104 GAGYDQIDVPFFSERGIQVSNVQSMADESTALTNLYLMIGTLRNFGDGALNLQKGQWLKG 163
Query: 467 LYTGSELAGKTLAILALAG 523
+ G++++GKTL IL + G
Sbjct: 164 VALGNDISGKTLGILGMGG 182
>UniRef50_A2SRM1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Methanocorpusculum
labreanum Z|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Methanocorpusculum
labreanum (strain ATCC 43576 / DSM 4855 / Z)
Length = 334
Score = 47.2 bits (107), Expect = 4e-04
Identities = 25/77 (32%), Positives = 42/77 (54%)
Frame = +2
Query: 305 IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSE 484
+DV +A K + V N P AN+L+ E T L+L L + + + K+G W + Y +
Sbjct: 93 VDVPAAKKHNIAVTNVPHANSLAVSEFTVALILTLMKKIPIMNKETKSGLWHK--YISQD 150
Query: 485 LAGKTLAILALAGSADR 535
++ KT+ I+ + GS R
Sbjct: 151 VSDKTIGIVGM-GSIGR 166
Score = 33.5 bits (73), Expect = 4.7
Identities = 19/55 (34%), Positives = 30/55 (54%), Gaps = 1/55 (1%)
Frame = +1
Query: 508 LGLGRVGR*VATRM-YAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+G+G +GR VA +M Y FG I+ + +D + +EL D+ L+D IT
Sbjct: 159 VGMGSIGRLVAKKMYYGFGCKILYYSRTRESDIEQELDAKFVELHDLCRLSDVIT 213
>UniRef50_Q7NEV2 Cluster: Phosphoglycerate dehydrogenase; n=6;
Bacteria|Rep: Phosphoglycerate dehydrogenase -
Gloeobacter violaceus
Length = 310
Score = 46.8 bits (106), Expect = 5e-04
Identities = 23/75 (30%), Positives = 37/75 (49%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
G GVDN+D +A G+ + N P ++ + + LAR ++AG W +
Sbjct: 79 GVGVDNVDFAAARALGIPIANTPAMFGAEVADVAVSYVTALARETFSVDREVRAGGWPKP 138
Query: 467 LYTGSELAGKTLAIL 511
G LAGKT+A++
Sbjct: 139 --CGVSLAGKTVALV 151
>UniRef50_Q5FKH9 Cluster: Glyoxylate reductase; n=1; Lactobacillus
acidophilus|Rep: Glyoxylate reductase - Lactobacillus
acidophilus
Length = 321
Score = 46.8 bits (106), Expect = 5e-04
Identities = 28/80 (35%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW--- 457
G G D+ID+D A +KG+ V N P + EL T+++ AR + AL+ G +
Sbjct: 77 GVGFDHIDIDYAREKGIVVTNCPNSVLRPTAELALTMIMASARRIRYYDHALREGVFLNV 136
Query: 458 DRALYTGSELAGKTLAILAL 517
D G + GKTL IL +
Sbjct: 137 DEYDSQGYTIEGKTLGILGM 156
>UniRef50_A6C853 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: D-3-phosphoglycerate
dehydrogenase - Planctomyces maris DSM 8797
Length = 328
Score = 46.8 bits (106), Expect = 5e-04
Identities = 22/55 (40%), Positives = 38/55 (69%), Gaps = 1/55 (1%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTK-MELEDIWPLADYIT 669
+GLGR+G+ VATR GM+++ +DPF + ++ A+ H K + LE++ +DY+T
Sbjct: 150 VGLGRIGQAVATRAIGMGMHVLAYDPFPN-EEFAKTHQIKLLSLEELLKQSDYVT 203
Score = 42.7 bits (96), Expect = 0.008
Identities = 24/79 (30%), Positives = 39/79 (49%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R G G D +D+ +A + + V PG N S E L++ +AR A+++G W+
Sbjct: 76 RYGVGFDAVDLAAADAQNIVVTITPGVNHHSVAEQAFALLMGIARMTRTQDRAVRSGEWE 135
Query: 461 RALYTGSELAGKTLAILAL 517
R L + G T+ I+ L
Sbjct: 136 REL--TPRVWGSTIGIVGL 152
>UniRef50_A3RV54 Cluster: 2-hydroxyacid dehydrogenase; n=5;
Burkholderiales|Rep: 2-hydroxyacid dehydrogenase -
Ralstonia solanacearum UW551
Length = 331
Score = 46.8 bits (106), Expect = 5e-04
Identities = 25/81 (30%), Positives = 40/81 (49%), Gaps = 4/81 (4%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR- 463
G G +N+DV + +GV V N P + + LML AR + + ++ G W +
Sbjct: 75 GVGYNNVDVAACTARGVVVTNTPDVLTQTTADFGFALMLATARRITESERFVRRGEWQKT 134
Query: 464 ALYT---GSELAGKTLAILAL 517
+Y GS++ G TL IL +
Sbjct: 135 GIYNQMLGSDIYGATLGILGM 155
>UniRef50_A1GFX2 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Salinispora arenicola
CNS205|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Salinispora arenicola
CNS205
Length = 302
Score = 46.8 bits (106), Expect = 5e-04
Identities = 28/76 (36%), Positives = 38/76 (50%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R G+G DNID+ + +G+ + P ANA + E T L L+R L AGR
Sbjct: 65 RPGSGTDNIDLLALAARGITLHRNPTANAAAVAEWTLLAALSLSRRAALGHNGLTAGRHL 124
Query: 461 RALYTGSELAGKTLAI 508
+A G LA + LAI
Sbjct: 125 KAACLGRPLAEQHLAI 140
>UniRef50_Q89LI6 Cluster: Blr4558 protein; n=6;
Bradyrhizobiaceae|Rep: Blr4558 protein - Bradyrhizobium
japonicum
Length = 329
Score = 46.4 bits (105), Expect = 6e-04
Identities = 28/91 (30%), Positives = 43/91 (47%), Gaps = 1/91 (1%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW- 457
R G G D +DV + ++ V ++ A AN+ S E +ML LA+ + +K G+W
Sbjct: 78 RIGVGYDAVDVPALSRRKVPLMVAGSANSPSVAEQALFMMLTLAKRAQEMHSCVKDGKWA 137
Query: 458 DRALYTGSELAGKTLAILALAGSADRWPLGC 550
DR +L GKT+ I+ R C
Sbjct: 138 DRLGMLPFDLYGKTVLIIGFGRIGTRTAKRC 168
>UniRef50_Q6A895 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Actinomycetales|Rep: D-3-phosphoglycerate dehydrogenase
- Propionibacterium acnes
Length = 417
Score = 46.4 bits (105), Expect = 6e-04
Identities = 22/73 (30%), Positives = 38/73 (52%)
Frame = +2
Query: 293 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY 472
G + +D+D+ + GV NAP +N S EL ++ LAR + +T + G W ++
Sbjct: 96 GTNQMDLDALAEAGVPAFNAPYSNTRSVVELVMAEIIALARRLGDRNTQMHNGVWRKSAI 155
Query: 473 TGSELAGKTLAIL 511
E+ G+ L I+
Sbjct: 156 GSHEIRGRRLGII 168
>UniRef50_Q5LT44 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=16; Proteobacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Silicibacter pomeroyi
Length = 330
Score = 46.4 bits (105), Expect = 6e-04
Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 3/78 (3%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-- 460
G G +ID D+ G+ V N P + ++ TLML++AR L+AG+W
Sbjct: 84 GVGYSHIDSDAVRAHGITVSNTPDVLSECTADIAMTLMLMVARRAGEGERELRAGQWTGW 143
Query: 461 RALY-TGSELAGKTLAIL 511
R + GS+++GK L I+
Sbjct: 144 RPTHLVGSKVSGKVLGIV 161
>UniRef50_Q1MQK2 Cluster: Phosphoglycerate dehydrogenase and related
dehydrogenases; n=1; Lawsonia intracellularis
PHE/MN1-00|Rep: Phosphoglycerate dehydrogenase and
related dehydrogenases - Lawsonia intracellularis
(strain PHE/MN1-00)
Length = 302
Score = 46.4 bits (105), Expect = 6e-04
Identities = 25/77 (32%), Positives = 42/77 (54%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
G +DNIDV+ A +K + + N P A++ E T L+L L R + +++G W +
Sbjct: 77 GKHLDNIDVEYAQEKNIIIYNPPKGYAIAVAEFTVGLILSLIRQIPYQDKEVRSGVWHKR 136
Query: 467 LYTGSELAGKTLAILAL 517
+ G+ L GK + I+ L
Sbjct: 137 I--GNLLHGKRVGIIGL 151
>UniRef50_Q1M6M5 Cluster: Putative glyoxylate reductase; n=1;
Rhizobium leguminosarum bv. viciae 3841|Rep: Putative
glyoxylate reductase - Rhizobium leguminosarum bv.
viciae (strain 3841)
Length = 312
Score = 46.4 bits (105), Expect = 6e-04
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
GAG D ID+ K+GV V A +L TL ++L R +V A + G W+R
Sbjct: 75 GAGSDKIDIPGLEKRGVRVRCVGEALTDDVADLAMTLTIMLCRDLVRADAFARGGEWERG 134
Query: 467 LY-TGSELAGKTLAILALAG 523
+ G G T+ I L+G
Sbjct: 135 RFDVGDSPVGMTIGIGGLSG 154
>UniRef50_Q120S8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Proteobacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Polaromonas sp. (strain JS666 / ATCC
BAA-500)
Length = 325
Score = 46.4 bits (105), Expect = 6e-04
Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 1/78 (1%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R G GVDNID+ +A + + V N P T L L + R VV +++GRW
Sbjct: 82 RYGIGVDNIDMAAAAARRIAVANVPDYGTDEVSTQTVALALAVVRQVVSHDREVRSGRWS 141
Query: 461 RALYTGS-ELAGKTLAIL 511
+ L G+TL ++
Sbjct: 142 TGVIKPMYRLRGRTLGLI 159
>UniRef50_A6GGA6 Cluster: Probable 2-hydroxyacid dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: Probable 2-hydroxyacid
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 327
Score = 46.4 bits (105), Expect = 6e-04
Identities = 26/78 (33%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
Frame = +2
Query: 293 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR--- 463
G DN+DV + + + V N PG + +L L+L AR++ AS + GRW
Sbjct: 83 GFDNVDVPACTARSIRVGNTPGVLTDATADLAMALLLSAARNLPAASLDAREGRWQTWSP 142
Query: 464 ALYTGSELAGKTLAILAL 517
+ G EL G TL ++ L
Sbjct: 143 TGWLGLELRGATLGVVGL 160
>UniRef50_Q7WNI7 Cluster: Putative dehydrogenase; n=1; Bordetella
bronchiseptica|Rep: Putative dehydrogenase - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 333
Score = 46.0 bits (104), Expect = 8e-04
Identities = 22/60 (36%), Positives = 35/60 (58%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
G GVD IDVD+A + G+ + G+NA EL L+L + R + + ++AG+W +A
Sbjct: 79 GIGVDRIDVDAARRLGIPLAITAGSNAGPVAELAVALILGVYRRLCYVNREMRAGQWPKA 138
>UniRef50_Q1CG62 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=8; Yersinia|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Yersinia pestis (biovar Antiqua strain
Nepal516)
Length = 316
Score = 46.0 bits (104), Expect = 8e-04
Identities = 20/60 (33%), Positives = 32/60 (53%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R G GVDNID+ +A K+G+ + N P + + L LAR + +++GRW+
Sbjct: 71 RYGVGVDNIDLSAARKRGMRICNVPDYGIEEVADHAAAMTLALARKLGRYEAGIRSGRWE 130
Score = 42.3 bits (95), Expect = 0.010
Identities = 18/29 (62%), Positives = 22/29 (75%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVS 594
+GLGR+ R ATRM FG IIGFDP+V+
Sbjct: 149 IGLGRIARAYATRMAVFGCRIIGFDPYVT 177
>UniRef50_A7HWK6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Parvibaculum
lavamentivorans DS-1|Rep: D-isomer specific
2-hydroxyacid dehydrogenase NAD-binding - Parvibaculum
lavamentivorans DS-1
Length = 306
Score = 46.0 bits (104), Expect = 8e-04
Identities = 21/57 (36%), Positives = 31/57 (54%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW 457
G+G + ID+ +A + V V N GANA + +L L+L R VV +AG+W
Sbjct: 64 GSGYEGIDIGAAARHNVTVTNTVGANAATVADLAVALLLASVRLVVTGDRLTRAGQW 120
>UniRef50_A1UEI9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=5; Mycobacterium|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Mycobacterium sp. (strain KMS)
Length = 321
Score = 46.0 bits (104), Expect = 8e-04
Identities = 30/77 (38%), Positives = 40/77 (51%), Gaps = 4/77 (5%)
Frame = +2
Query: 293 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDR 463
G DNIDV +A GV V N PG + + T L+L + R VV L++ R W
Sbjct: 81 GYDNIDVAAAHAAGVTVTNTPGVLDNATADHTFALILAVTRRVVDGDRFLRSRRPWIWGP 140
Query: 464 ALYTGSEL-AGKTLAIL 511
+ TG ++ AG TL IL
Sbjct: 141 RMLTGLDVSAGATLGIL 157
>UniRef50_Q752A0 Cluster: AFR675Wp; n=3; Saccharomycetales|Rep:
AFR675Wp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 353
Score = 46.0 bits (104), Expect = 8e-04
Identities = 27/83 (32%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Frame = +2
Query: 287 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 466
GAG D ID +S K+ + V N PG + L+L R+ L+ GRW A
Sbjct: 89 GAGYDQIDPESFTKRQIQVANVPGLVNAPTADTHVFLLLAALRNFCHGQLLLRQGRWPDA 148
Query: 467 LYTGS----ELAGKTLAILALAG 523
G+ + AGKT+ +L + G
Sbjct: 149 PVAGTPFGHDPAGKTVGVLGMGG 171
>UniRef50_Q5KYJ7 Cluster: Dehydrogenase; n=3; Firmicutes|Rep:
Dehydrogenase - Geobacillus kaustophilus
Length = 334
Score = 45.6 bits (103), Expect = 0.001
Identities = 27/83 (32%), Positives = 45/83 (54%), Gaps = 4/83 (4%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 460
R G GV+ +DVD+A +KG+ V N + + L+L LAR +V + +K+G W+
Sbjct: 74 RYGVGVNTVDVDAATEKGIIVANVTDYSIDEVSDHALALLLSLARKIVKLNHEVKSGTWN 133
Query: 461 ----RALYTGSELAGKTLAILAL 517
+ +Y L G+TL ++ L
Sbjct: 134 FNVGKPIY---RLRGRTLGLVGL 153
Score = 43.6 bits (98), Expect = 0.004
Identities = 18/54 (33%), Positives = 34/54 (62%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYIT 669
+GLGR+ + +A + AFG+ +I +DP+V A + + + L D++ +DYI+
Sbjct: 151 VGLGRIPQALAKKAQAFGLRVIAYDPYVPAKVADELNVQLLGLNDVFRQSDYIS 204
>UniRef50_Q4PK14 Cluster: Predicted D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=1; uncultured bacterium
MedeBAC49C08|Rep: Predicted D-isomer specific
2-hydroxyacid dehydrogenase family protein - uncultured
bacterium MedeBAC49C08
Length = 395
Score = 45.6 bits (103), Expect = 0.001
Identities = 21/47 (44%), Positives = 30/47 (63%)
Frame = +2
Query: 281 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 421
RAGAGV+NI V+ K G+ V N PGANA + E+ +L+ +R +
Sbjct: 57 RAGAGVNNIPVEECSKIGIPVFNTPGANANAVKEMVLAALLMSSRGI 103
Score = 33.5 bits (73), Expect = 4.7
Identities = 18/57 (31%), Positives = 30/57 (52%), Gaps = 3/57 (5%)
Frame = +1
Query: 508 LGLGRVGR*VATRMYAFGMNIIGFDPFVSADQCAQFHC---TKMELEDIWPLADYIT 669
+G+G +G VA GM +IGFDP ++ + K +E+I+ +DY+T
Sbjct: 145 VGMGAIGAKVAEMGVMLGMRVIGFDPQITVEAAWALPNEVERKETIEEIFKESDYVT 201
>UniRef50_Q4IXK9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic domain:D- isomer specific
2-hydroxyacid dehydrogenase, NAD binding domain; n=1;
Azotobacter vinelandii AvOP|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic domain:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD binding domain
- Azotobacter vinelandii AvOP
Length = 388
Score = 45.6 bits (103), Expect = 0.001
Identities = 25/69 (36%), Positives = 39/69 (56%)
Frame = +2
Query: 302 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGS 481
++D+D+ ++GV V G+ ++ EL TL+L R ++PA A + GRW + G
Sbjct: 147 HLDLDACTRRGVAVAEGRGS-PIAPAELAWTLILNARRRLLPAIAAFREGRWQTNI--GE 203
Query: 482 ELAGKTLAI 508
LAG TL I
Sbjct: 204 RLAGLTLGI 212
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 692,191,034
Number of Sequences: 1657284
Number of extensions: 15175600
Number of successful extensions: 80457
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 65907
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 78693
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 51239674196
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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