Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= NV021731
(715 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q00610 Cluster: Clathrin heavy chain 1; n=54; Eukaryota... 164 2e-39
UniRef50_Q4S928 Cluster: Chromosome undetermined SCAF14702, whol... 163 4e-39
UniRef50_P53675 Cluster: Clathrin heavy chain 2; n=87; Eukaryota... 157 2e-37
UniRef50_A6R3L7 Cluster: Clathrin heavy chain; n=1; Ajellomyces ... 122 9e-27
UniRef50_P22137 Cluster: Clathrin heavy chain; n=13; Ascomycota|... 118 1e-25
UniRef50_Q8I5L6 Cluster: Clathrin heavy chain, putative; n=10; E... 107 3e-22
UniRef50_A0CHK3 Cluster: Chromosome undetermined scaffold_182, w... 107 3e-22
UniRef50_A2GL34 Cluster: Clathrin and VPS domain-containing prot... 105 1e-21
UniRef50_A5JZZ8 Cluster: Clathrin heavy chain, putative; n=2; Pl... 104 2e-21
UniRef50_Q5CW85 Cluster: Clathrin heavy chain; n=2; Cryptosporid... 103 6e-21
UniRef50_Q1EQ28 Cluster: Clathrin heavy chain; n=4; cellular org... 98 2e-19
UniRef50_Q4Q1R2 Cluster: Clathrin heavy chain, putative; n=10; E... 96 7e-19
UniRef50_Q0UXK7 Cluster: Putative uncharacterized protein; n=1; ... 81 2e-14
UniRef50_A7AVF3 Cluster: Clathrin heavy chain; n=1; Babesia bovi... 77 6e-13
UniRef50_Q4MZN7 Cluster: Clathrin heavy chain, putative; n=1; Th... 66 6e-10
UniRef50_Q4UBV3 Cluster: Clathrin heavy chain, putative; n=1; Th... 54 3e-06
UniRef50_Q8UUQ8 Cluster: Clathrin heavy-chain; n=15; Eukaryota|R... 46 0.001
UniRef50_P74408 Cluster: Slr0286 protein; n=1; Synechocystis sp.... 38 0.25
UniRef50_UPI0000ECD20F Cluster: DJ-1-binding protein (CAP-bindin... 34 3.0
UniRef50_Q8KEA6 Cluster: Putative uncharacterized protein; n=1; ... 34 3.0
UniRef50_A6G726 Cluster: PBS lyase HEAT-like repeat protein; n=1... 33 7.0
UniRef50_Q23FZ0 Cluster: Sec1 family protein; n=1; Tetrahymena t... 33 9.2
UniRef50_O18004 Cluster: Putative uncharacterized protein fbxb-8... 33 9.2
>UniRef50_Q00610 Cluster: Clathrin heavy chain 1; n=54; Eukaryota|Rep:
Clathrin heavy chain 1 - Homo sapiens (Human)
Length = 1675
Score = 164 bits (398), Expect = 2e-39
Identities = 73/84 (86%), Positives = 78/84 (92%)
Frame = +2
Query: 254 GSNEPATHNALAKIYIDSNNNPERFLRENQWYDSRVVGRYCEKRDPHLACVAYERGQCDR 433
G EPATHNALAKIYIDSNNNPERFLREN +YDSRVVG+YCEKRDPHLACVAYERGQCD
Sbjct: 869 GCEEPATHNALAKIYIDSNNNPERFLRENPYYDSRVVGKYCEKRDPHLACVAYERGQCDL 928
Query: 434 ELIAVCNDNSLFKTQARYLVRRKD 505
ELI VCN+NSLFK+ +RYLVRRKD
Sbjct: 929 ELINVCNENSLFKSLSRYLVRRKD 952
Score = 143 bits (347), Expect = 3e-33
Identities = 68/83 (81%), Positives = 72/83 (86%)
Frame = +3
Query: 6 DLVLYLYRNSLQKYIEIYVQKVNPSRLPXXXXXXXXXXCAEDIIKNLILVVRGQFSTDEL 185
DLVLYLYRN+LQKYIEIYVQKVNPSRLP C+ED+IKNLILVVRGQFSTDEL
Sbjct: 786 DLVLYLYRNNLQKYIEIYVQKVNPSRLPVVIGGLLDVDCSEDVIKNLILVVRGQFSTDEL 845
Query: 186 VAEVEKRNRLKLLLPWLETRVHE 254
VAEVEKRNRLKLLLPWLE R+HE
Sbjct: 846 VAEVEKRNRLKLLLPWLEARIHE 868
Score = 121 bits (292), Expect = 2e-26
Identities = 58/69 (84%), Positives = 63/69 (91%)
Frame = +1
Query: 508 DLWLEVLSEENPYKRQLIDQVVQTALSETQDPEDISVTVKAFMTADLPNELIELLEKIVP 687
+LW VL E NPY+R LIDQVVQTALSETQDPE++SVTVKAFMTADLPNELIELLEKIV
Sbjct: 954 ELWGSVLLESNPYRRPLIDQVVQTALSETQDPEEVSVTVKAFMTADLPNELIELLEKIVL 1013
Query: 688 DNSVFSDHR 714
DNSVFS+HR
Sbjct: 1014 DNSVFSEHR 1022
>UniRef50_Q4S928 Cluster: Chromosome undetermined SCAF14702, whole
genome shotgun sequence; n=4; Eumetazoa|Rep: Chromosome
undetermined SCAF14702, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1909
Score = 163 bits (396), Expect = 4e-39
Identities = 72/84 (85%), Positives = 79/84 (94%)
Frame = +2
Query: 254 GSNEPATHNALAKIYIDSNNNPERFLRENQWYDSRVVGRYCEKRDPHLACVAYERGQCDR 433
G EPATHNALAKIYIDSNNNPERFLREN +YDSRVVG+YCEKRDPHLACVAYERGQCD+
Sbjct: 922 GCEEPATHNALAKIYIDSNNNPERFLRENPYYDSRVVGKYCEKRDPHLACVAYERGQCDQ 981
Query: 434 ELIAVCNDNSLFKTQARYLVRRKD 505
ELI VCN+NSLFK+ +RYLVRRK+
Sbjct: 982 ELIHVCNENSLFKSLSRYLVRRKN 1005
Score = 145 bits (351), Expect = 1e-33
Identities = 69/83 (83%), Positives = 72/83 (86%)
Frame = +3
Query: 6 DLVLYLYRNSLQKYIEIYVQKVNPSRLPXXXXXXXXXXCAEDIIKNLILVVRGQFSTDEL 185
DLVLYLYRNSLQKYIEIYVQKVNPSRLP CAED+IKNLI+VVRGQFSTDEL
Sbjct: 839 DLVLYLYRNSLQKYIEIYVQKVNPSRLPVVIGGLLDVDCAEDVIKNLIMVVRGQFSTDEL 898
Query: 186 VAEVEKRNRLKLLLPWLETRVHE 254
VAEVEKRNRLKLLLPWLE R+HE
Sbjct: 899 VAEVEKRNRLKLLLPWLEARIHE 921
Score = 96.3 bits (229), Expect = 7e-19
Identities = 47/53 (88%), Positives = 50/53 (94%)
Frame = +1
Query: 556 LIDQVVQTALSETQDPEDISVTVKAFMTADLPNELIELLEKIVPDNSVFSDHR 714
L QVVQTALSETQDPE++SVTVKAFMTADLPNELIELLEKIV DNSVFS+HR
Sbjct: 1080 LSPQVVQTALSETQDPEEVSVTVKAFMTADLPNELIELLEKIVLDNSVFSEHR 1132
>UniRef50_P53675 Cluster: Clathrin heavy chain 2; n=87; Eukaryota|Rep:
Clathrin heavy chain 2 - Homo sapiens (Human)
Length = 1640
Score = 157 bits (382), Expect = 2e-37
Identities = 71/84 (84%), Positives = 76/84 (90%)
Frame = +2
Query: 254 GSNEPATHNALAKIYIDSNNNPERFLRENQWYDSRVVGRYCEKRDPHLACVAYERGQCDR 433
G EPATHNALAKIYIDSNN+PE FLREN +YDS VVGRYCEKRDPHLACVAYERGQCD
Sbjct: 869 GCEEPATHNALAKIYIDSNNSPECFLRENAYYDSSVVGRYCEKRDPHLACVAYERGQCDL 928
Query: 434 ELIAVCNDNSLFKTQARYLVRRKD 505
ELI VCN+NSLFK++ARYLV RKD
Sbjct: 929 ELIKVCNENSLFKSEARYLVCRKD 952
Score = 130 bits (314), Expect = 3e-29
Identities = 66/113 (58%), Positives = 82/113 (72%), Gaps = 4/113 (3%)
Frame = +3
Query: 6 DLVLYLYRNSLQKYIEIYVQKVNPSRLPXXXXXXXXXXCAEDIIKNLILVVRGQFSTDEL 185
DLVLYLYRN+LQ+YIEIYVQKVNPSR P C+E++IK+LI+ VRGQFSTDEL
Sbjct: 786 DLVLYLYRNNLQRYIEIYVQKVNPSRTPAVIGGLLDVDCSEEVIKHLIMAVRGQFSTDEL 845
Query: 186 VAEVEKRNRLKLLLPWLETRVHEA----ATNQPHIML*PRSTSIPTTILRDSS 332
VAEVEKRNRLKLLLPWLE+++ E AT+ + S + P LR+++
Sbjct: 846 VAEVEKRNRLKLLLPWLESQIQEGCEEPATHNALAKIYIDSNNSPECFLRENA 898
Score = 120 bits (290), Expect = 3e-26
Identities = 58/69 (84%), Positives = 63/69 (91%)
Frame = +1
Query: 508 DLWLEVLSEENPYKRQLIDQVVQTALSETQDPEDISVTVKAFMTADLPNELIELLEKIVP 687
+LW VL E NP +RQLIDQVVQTALSET+DPE+ISVTVKAFMTADLPNELIELLEKIV
Sbjct: 954 ELWAHVLEETNPSRRQLIDQVVQTALSETRDPEEISVTVKAFMTADLPNELIELLEKIVL 1013
Query: 688 DNSVFSDHR 714
DNSVFS+HR
Sbjct: 1014 DNSVFSEHR 1022
>UniRef50_A6R3L7 Cluster: Clathrin heavy chain; n=1; Ajellomyces
capsulatus NAm1|Rep: Clathrin heavy chain - Ajellomyces
capsulatus NAm1
Length = 1631
Score = 122 bits (294), Expect = 9e-27
Identities = 55/94 (58%), Positives = 72/94 (76%)
Frame = +2
Query: 224 PSLAGNKST*GSNEPATHNALAKIYIDSNNNPERFLRENQWYDSRVVGRYCEKRDPHLAC 403
P L +T G+ + A +NALAKIYIDSNNNPE+FL+EN YD +VG+YCEKRDP+LA
Sbjct: 815 PFLENTLAT-GNQQQAVYNALAKIYIDSNNNPEKFLKENDLYDPLIVGKYCEKRDPNLAY 873
Query: 404 VAYERGQCDRELIAVCNDNSLFKTQARYLVRRKD 505
+AY +GQ D ELI + N+NS+++ QARYL+ R D
Sbjct: 874 IAYRKGQNDLELINITNENSMYRAQARYLLERAD 907
Score = 83.0 bits (196), Expect = 7e-15
Identities = 42/79 (53%), Positives = 52/79 (65%), Gaps = 1/79 (1%)
Frame = +3
Query: 6 DLVLYLYRNSLQKYIEIYVQKVNPSRLPXXXXXXXXXXCAEDIIKNLILVV-RGQFSTDE 182
DLVLYLY++ + IE+YVQ+VNPSR P C E IIKNL+ V D+
Sbjct: 740 DLVLYLYQSQQYRSIEVYVQRVNPSRTPAVVGGLLDVDCEESIIKNLLSTVDAASIPIDD 799
Query: 183 LVAEVEKRNRLKLLLPWLE 239
LV+EVE RNRLK+LLP+LE
Sbjct: 800 LVSEVESRNRLKILLPFLE 818
Score = 80.2 bits (189), Expect = 5e-14
Identities = 36/68 (52%), Positives = 52/68 (76%)
Frame = +1
Query: 508 DLWLEVLSEENPYKRQLIDQVVQTALSETQDPEDISVTVKAFMTADLPNELIELLEKIVP 687
++W VL+ N ++R L+DQVV TA+ E+ +P+ +S+ VKAF+ ADLP ELIELLEKI+
Sbjct: 909 EIWAFVLNANNIHRRALVDQVVATAVPESAEPDKVSIAVKAFLDADLPGELIELLEKIIL 968
Query: 688 DNSVFSDH 711
+ S FSD+
Sbjct: 969 EPSPFSDN 976
>UniRef50_P22137 Cluster: Clathrin heavy chain; n=13; Ascomycota|Rep:
Clathrin heavy chain - Saccharomyces cerevisiae (Baker's
yeast)
Length = 1653
Score = 118 bits (285), Expect = 1e-25
Identities = 52/84 (61%), Positives = 67/84 (79%)
Frame = +2
Query: 254 GSNEPATHNALAKIYIDSNNNPERFLRENQWYDSRVVGRYCEKRDPHLACVAYERGQCDR 433
G + A +NALAKIYIDSNN+PE+FL+EN YD+ VG YCEKRDP+LA +AYE+GQ D
Sbjct: 875 GIQDQAVYNALAKIYIDSNNSPEKFLKENDQYDTLDVGHYCEKRDPYLAYIAYEKGQNDD 934
Query: 434 ELIAVCNDNSLFKTQARYLVRRKD 505
+LI + N+NS++K QARYL+ R D
Sbjct: 935 DLIRITNENSMYKYQARYLLERSD 958
Score = 78.2 bits (184), Expect = 2e-13
Identities = 38/88 (43%), Positives = 55/88 (62%)
Frame = +3
Query: 6 DLVLYLYRNSLQKYIEIYVQKVNPSRLPXXXXXXXXXXCAEDIIKNLILVVRGQFSTDEL 185
+++LYLY++ K+IE YVQ+VNPS+ C E I++L+ V GQ +EL
Sbjct: 792 EMILYLYKSQNLKFIETYVQQVNPSKTAQVVGALLDMDCDEAFIQSLLQSVLGQVPINEL 851
Query: 186 VAEVEKRNRLKLLLPWLETRVHEAATNQ 269
EVEKRNRLK+LLP+LE + + +Q
Sbjct: 852 TTEVEKRNRLKILLPFLEQSLSQGIQDQ 879
Score = 77.0 bits (181), Expect = 4e-13
Identities = 36/68 (52%), Positives = 51/68 (75%)
Frame = +1
Query: 508 DLWLEVLSEENPYKRQLIDQVVQTALSETQDPEDISVTVKAFMTADLPNELIELLEKIVP 687
DLW +VL++EN ++RQLID V+ + E DPE +S+TV+AFMT L ELIELLEKI+
Sbjct: 960 DLWNKVLNQENIHRRQLIDSVISVGIPELTDPEPVSLTVQAFMTNGLKLELIELLEKIIL 1019
Query: 688 DNSVFSDH 711
+ S F+++
Sbjct: 1020 EPSPFNEN 1027
>UniRef50_Q8I5L6 Cluster: Clathrin heavy chain, putative; n=10;
Eukaryota|Rep: Clathrin heavy chain, putative -
Plasmodium falciparum (isolate 3D7)
Length = 1997
Score = 107 bits (257), Expect = 3e-22
Identities = 47/78 (60%), Positives = 59/78 (75%), Gaps = 2/78 (2%)
Frame = +2
Query: 275 HNALAKIYIDSNNNPERFLRENQWYDSRVVGRYCEKRDPHLACVAYER--GQCDRELIAV 448
HNALAKIYID N +PE FL+ N +YD +++G+YCE DPHLA AYER G+CD ELI +
Sbjct: 1081 HNALAKIYIDLNKDPENFLKNNNFYDKKMIGKYCEDLDPHLAYTAYERSNGECDEELIYI 1140
Query: 449 CNDNSLFKTQARYLVRRK 502
+ N LFK QARYL+ R+
Sbjct: 1141 TSKNGLFKLQARYLISRQ 1158
Score = 79.8 bits (188), Expect = 6e-14
Identities = 39/88 (44%), Positives = 53/88 (60%)
Frame = +3
Query: 3 DDLVLYLYRNSLQKYIEIYVQKVNPSRLPXXXXXXXXXXCAEDIIKNLILVVRGQFSTDE 182
++L YLY+NSL KYIE+YV KVNP+ +ED + NL+ ++ +
Sbjct: 990 EELAEYLYKNSLLKYIEVYVIKVNPNNAHKVIGVLLDLDASEDFLLNLLNNIKNISNIGN 1049
Query: 183 LVAEVEKRNRLKLLLPWLETRVHEAATN 266
L+ EKRNRLKLLLPWLE+R +E N
Sbjct: 1050 LIEIAEKRNRLKLLLPWLESRANEGYEN 1077
Score = 76.2 bits (179), Expect = 8e-13
Identities = 36/74 (48%), Positives = 54/74 (72%)
Frame = +1
Query: 493 AQEGSDLWLEVLSEENPYKRQLIDQVVQTALSETQDPEDISVTVKAFMTADLPNELIELL 672
+++ +LW VL E N Y++ +IDQV+ + L E+ + ++I+VTVKAF+ L +ELIELL
Sbjct: 1156 SRQSIELWKVVLDETNKYRKNVIDQVIGSTLIESNNADEITVTVKAFIEKKLSSELIELL 1215
Query: 673 EKIVPDNSVFSDHR 714
EKIV NS FSD++
Sbjct: 1216 EKIVLHNSEFSDNK 1229
>UniRef50_A0CHK3 Cluster: Chromosome undetermined scaffold_182, whole
genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_182, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 1690
Score = 107 bits (257), Expect = 3e-22
Identities = 48/88 (54%), Positives = 68/88 (77%), Gaps = 2/88 (2%)
Frame = +2
Query: 248 T*GSNEPATHNALAKIYIDSNNNPERFLRENQWYDSRVVGRYCEKRDPHLACVAYER--G 421
T G+ PA HNALAKI ID++ +P+ FL NQ+YD++ VG++CE+RDP LA +AY+R G
Sbjct: 859 TEGNQIPAIHNALAKIKIDTSQDPDGFLINNQFYDAKAVGKFCEERDPQLAVLAYKRAWG 918
Query: 422 QCDRELIAVCNDNSLFKTQARYLVRRKD 505
QCD+ELI + N N +++ QA+YLV R+D
Sbjct: 919 QCDQELINLTNKNEMYRVQAKYLVERQD 946
Score = 75.4 bits (177), Expect = 1e-12
Identities = 36/84 (42%), Positives = 48/84 (57%)
Frame = +3
Query: 3 DDLVLYLYRNSLQKYIEIYVQKVNPSRLPXXXXXXXXXXCAEDIIKNLILVVRGQFSTDE 182
D+L YLY+N +YIEIY+ KVNP+ P C E +K L+ +RG +
Sbjct: 777 DELTRYLYKNGFTRYIEIYIFKVNPNAAPGVFGTLIDLECDEVYLKQLLYNIRGMCPIEP 836
Query: 183 LVAEVEKRNRLKLLLPWLETRVHE 254
V E EKRN+L++L WLE RV E
Sbjct: 837 TVDEFEKRNKLRVLEQWLEARVTE 860
Score = 64.9 bits (151), Expect = 2e-09
Identities = 30/69 (43%), Positives = 47/69 (68%)
Frame = +1
Query: 508 DLWLEVLSEENPYKRQLIDQVVQTALSETQDPEDISVTVKAFMTADLPNELIELLEKIVP 687
DLW VL E NP+++ LID V+Q AL ++++ +++ VKAF+ A +P EL+ LLEK+V
Sbjct: 948 DLWAGVLQETNPHRKNLIDYVIQ-ALQDSKNVDEVQAAVKAFVLAKIPYELLGLLEKLVL 1006
Query: 688 DNSVFSDHR 714
N F ++
Sbjct: 1007 HNPEFMQYK 1015
>UniRef50_A2GL34 Cluster: Clathrin and VPS domain-containing
protein; n=1; Trichomonas vaginalis G3|Rep: Clathrin and
VPS domain-containing protein - Trichomonas vaginalis G3
Length = 838
Score = 105 bits (252), Expect = 1e-21
Identities = 47/90 (52%), Positives = 62/90 (68%)
Frame = +2
Query: 254 GSNEPATHNALAKIYIDSNNNPERFLRENQWYDSRVVGRYCEKRDPHLACVAYERGQCDR 433
GS +PAT+N + + + NPER LRENQ+YD + VG KRD HLAC+AY +GQCD
Sbjct: 428 GSVDPATNNGIVLLAYNMGRNPERALRENQYYDPKFVGEILAKRDAHLACIAYAKGQCDD 487
Query: 434 ELIAVCNDNSLFKTQARYLVRRKDQTSGSR 523
ELI + N + L+K QARYLV R+D+ +R
Sbjct: 488 ELIELTNTHQLYKEQARYLVNRQDENLWAR 517
Score = 78.6 bits (185), Expect = 1e-13
Identities = 32/72 (44%), Positives = 54/72 (75%)
Frame = +1
Query: 496 QEGSDLWLEVLSEENPYKRQLIDQVVQTALSETQDPEDISVTVKAFMTADLPNELIELLE 675
++ +LW VL+ ENP+ + ++D V+ TAL E +DP+ +S+TVKAF+TAD+P +L+ LLE
Sbjct: 509 RQDENLWARVLNPENPHMKLVVDAVISTALPECEDPDKVSMTVKAFITADIPAQLLGLLE 568
Query: 676 KIVPDNSVFSDH 711
K+V ++ F ++
Sbjct: 569 KVVMESPQFKEN 580
Score = 51.6 bits (118), Expect = 2e-05
Identities = 35/113 (30%), Positives = 53/113 (46%), Gaps = 4/113 (3%)
Frame = +3
Query: 3 DDLVLYLYRNSLQKYIEIYVQKVNPSRLPXXXXXXXXXXCAEDIIKNLILVVRGQFSTDE 182
+DL YLY+ + + +EIY+QK NP+ ++ I LI V+ +E
Sbjct: 344 EDLTKYLYKKNASRELEIYIQKFNPAMAGRVIGALIDIEAPQEYIVKLINSVQHTAPMEE 403
Query: 183 LVAEVEKRNRLKLLLPWLETRVH----EAATNQPHIML*PRSTSIPTTILRDS 329
L+ E KR RL+LL LE R + ATN ++L P LR++
Sbjct: 404 LIKETMKRERLRLLQQILEQRQASGSVDPATNNGIVLLAYNMGRNPERALREN 456
>UniRef50_A5JZZ8 Cluster: Clathrin heavy chain, putative; n=2;
Plasmodium|Rep: Clathrin heavy chain, putative -
Plasmodium vivax
Length = 1935
Score = 104 bits (250), Expect = 2e-21
Identities = 47/90 (52%), Positives = 62/90 (68%), Gaps = 2/90 (2%)
Frame = +2
Query: 239 NKST*GSNEPATHNALAKIYIDSNNNPERFLRENQWYDSRVVGRYCEKRDPHLACVAYER 418
++S G HNALAKIYID N +PE FL+ N +YD +++G+YCE DPHLA YE+
Sbjct: 1019 SRSNEGYENIELHNALAKIYIDLNKDPENFLKNNNFYDKKLIGKYCEDLDPHLAYTVYEK 1078
Query: 419 --GQCDRELIAVCNDNSLFKTQARYLVRRK 502
G+CD ELI + + N LFK QA+YLV R+
Sbjct: 1079 SNGECDEELINITSKNGLFKLQAKYLVSRQ 1108
Score = 79.0 bits (186), Expect = 1e-13
Identities = 39/88 (44%), Positives = 53/88 (60%)
Frame = +3
Query: 3 DDLVLYLYRNSLQKYIEIYVQKVNPSRLPXXXXXXXXXXCAEDIIKNLILVVRGQFSTDE 182
++L YLY+NSL KYIE+YV KVNP+ +ED + NL+ ++ +
Sbjct: 940 EELAEYLYKNSLLKYIEVYVIKVNPNNAHKVIGVLLDLDASEDFLLNLLNNIKNISNIGN 999
Query: 183 LVAEVEKRNRLKLLLPWLETRVHEAATN 266
L+ EKRNRLKLLLPWLE+R +E N
Sbjct: 1000 LIEIAEKRNRLKLLLPWLESRSNEGYEN 1027
Score = 79.0 bits (186), Expect = 1e-13
Identities = 37/74 (50%), Positives = 54/74 (72%)
Frame = +1
Query: 493 AQEGSDLWLEVLSEENPYKRQLIDQVVQTALSETQDPEDISVTVKAFMTADLPNELIELL 672
+++ +LW VL E N Y++ +IDQV+ + L E+ + E+I+VTVKAF+ L +ELIELL
Sbjct: 1106 SRQSMELWKRVLDESNKYRKNVIDQVIGSTLIESNNAEEITVTVKAFIEKKLSSELIELL 1165
Query: 673 EKIVPDNSVFSDHR 714
EKIV NS FSD++
Sbjct: 1166 EKIVLHNSEFSDNK 1179
>UniRef50_Q5CW85 Cluster: Clathrin heavy chain; n=2;
Cryptosporidium|Rep: Clathrin heavy chain -
Cryptosporidium parvum Iowa II
Length = 2007
Score = 103 bits (246), Expect = 6e-21
Identities = 47/86 (54%), Positives = 60/86 (69%), Gaps = 2/86 (2%)
Frame = +2
Query: 254 GSNEPATHNALAKIYIDSNNNPERFLRENQWYDSRVVGRYCEKRDPHLACVAYER--GQC 427
G +PA HNALAKIYID N + E FL+ N YD++ +G YCE RDP+LA +AY + GQC
Sbjct: 1049 GYQDPALHNALAKIYIDMNKDSENFLKTNPHYDAKTIGDYCEDRDPYLAYIAYRKAWGQC 1108
Query: 428 DRELIAVCNDNSLFKTQARYLVRRKD 505
D E+I V N L++ ARYLV R+D
Sbjct: 1109 DDEIIQVTYKNDLYRLLARYLVERQD 1134
Score = 79.0 bits (186), Expect = 1e-13
Identities = 38/87 (43%), Positives = 54/87 (62%), Gaps = 3/87 (3%)
Frame = +3
Query: 3 DDLVLYLYRNSLQKYIEIYVQKVNPSRLPXXXXXXXXXXCAEDIIKNLILVVR---GQFS 173
++L+ YLY SL KYI++Y K+NPS+ P +ED++K+L+ ++ FS
Sbjct: 962 EELISYLYHMSLYKYIQVYTLKINPSQTPLVIGTLIDLDGSEDLVKSLLQEIKTLGSSFS 1021
Query: 174 TDELVAEVEKRNRLKLLLPWLETRVHE 254
EL+ + E RNRLKLLL WLE RV E
Sbjct: 1022 FGELIQQAENRNRLKLLLSWLEERVQE 1048
Score = 46.0 bits (104), Expect = 0.001
Identities = 23/59 (38%), Positives = 41/59 (69%), Gaps = 3/59 (5%)
Frame = +1
Query: 547 KRQLIDQVVQTALSETQDP-EDISVTVKAFMTADLPNELIELLEKIV--PDNSVFSDHR 714
++ +IDQV + L E + E+IS ++AF+ A++PN L+E+LEKI+ +N+ FS ++
Sbjct: 1158 RQAIIDQVTSSILPEFYNKSEEISCVIRAFINAEVPNSLLEVLEKIIFHVNNTEFSQNK 1216
>UniRef50_Q1EQ28 Cluster: Clathrin heavy chain; n=4; cellular
organisms|Rep: Clathrin heavy chain - Entamoeba
histolytica
Length = 1622
Score = 97.9 bits (233), Expect = 2e-19
Identities = 42/84 (50%), Positives = 60/84 (71%)
Frame = +2
Query: 254 GSNEPATHNALAKIYIDSNNNPERFLRENQWYDSRVVGRYCEKRDPHLACVAYERGQCDR 433
GS + + H ALAK+Y+D + E+FL + +YDS +VG+YCE RDP+L+ + Y+R D
Sbjct: 826 GSPDVSLHTALAKVYVDQGKDAEKFLNNDMYYDSLIVGKYCEDRDPYLSYICYKRKNLDD 885
Query: 434 ELIAVCNDNSLFKTQARYLVRRKD 505
ELI V N ++LFK QA+YLV R+D
Sbjct: 886 ELIDVTNRHNLFKYQAKYLVERED 909
Score = 77.4 bits (182), Expect = 3e-13
Identities = 36/86 (41%), Positives = 49/86 (56%)
Frame = +3
Query: 3 DDLVLYLYRNSLQKYIEIYVQKVNPSRLPXXXXXXXXXXCAEDIIKNLILVVRGQFSTDE 182
+++ YLY+N ++IE YV+K+NP P C ED I+ LI V G DE
Sbjct: 742 EEMTQYLYQNGNHRFIEAYVKKINPMNTPKVVGALLDCGCGEDYIQQLINAVGGICPADE 801
Query: 183 LVAEVEKRNRLKLLLPWLETRVHEAA 260
L+ E RNRL +LLPWLE R+ E +
Sbjct: 802 LIKTCESRNRLIILLPWLEQRLSEGS 827
Score = 77.4 bits (182), Expect = 3e-13
Identities = 34/70 (48%), Positives = 51/70 (72%)
Frame = +1
Query: 496 QEGSDLWLEVLSEENPYKRQLIDQVVQTALSETQDPEDISVTVKAFMTADLPNELIELLE 675
+E DLW +VL+EEN +++ +++QV+ TAL E DP I TV+AF+ DLPN+LI+LL+
Sbjct: 907 REDLDLWNKVLTEENEHRKSVVEQVIHTALPECTDPNQILKTVQAFLQNDLPNDLIDLLD 966
Query: 676 KIVPDNSVFS 705
K+V N +S
Sbjct: 967 KLVSQNPEYS 976
>UniRef50_Q4Q1R2 Cluster: Clathrin heavy chain, putative; n=10;
Eukaryota|Rep: Clathrin heavy chain, putative -
Leishmania major
Length = 1680
Score = 96.3 bits (229), Expect = 7e-19
Identities = 40/80 (50%), Positives = 59/80 (73%)
Frame = +2
Query: 263 EPATHNALAKIYIDSNNNPERFLRENQWYDSRVVGRYCEKRDPHLACVAYERGQCDRELI 442
+ A +NALAKIY+D +PE+FL EN++YD++VVG+YCE RDP+LA + Y G C +I
Sbjct: 887 DKALYNALAKIYVDIGQSPEQFLSENEYYDAQVVGKYCETRDPNLAYIIYCCGHCSEMMI 946
Query: 443 AVCNDNSLFKTQARYLVRRK 502
+C+ N ++K ARYLV+ +
Sbjct: 947 DLCHRNGMYKQLARYLVKEQ 966
Score = 60.1 bits (139), Expect = 5e-08
Identities = 28/63 (44%), Positives = 42/63 (66%)
Frame = +1
Query: 496 QEGSDLWLEVLSEENPYKRQLIDQVVQTALSETQDPEDISVTVKAFMTADLPNELIELLE 675
++ DLW VL + + ++QLI+ V Q AL E++ E++S TV+AFM A+L EL LL
Sbjct: 965 EQSLDLWASVLGQNSAERQQLIESVQQIALPESESSEEVSTTVRAFMNANLTEELTSLLG 1024
Query: 676 KIV 684
+IV
Sbjct: 1025 QIV 1027
Score = 56.0 bits (129), Expect = 9e-07
Identities = 30/89 (33%), Positives = 46/89 (51%)
Frame = +3
Query: 3 DDLVLYLYRNSLQKYIEIYVQKVNPSRLPXXXXXXXXXXCAEDIIKNLILVVRGQFSTDE 182
+++V YL + +IE YV + NP + P +E+ IKN++ VV +E
Sbjct: 800 NEMVHYLVETGNESFIEQYVTRRNPGKTPQVVQALIECNVSEERIKNMLTVVGAMCPIEE 859
Query: 183 LVAEVEKRNRLKLLLPWLETRVHEAATNQ 269
LV VE+ RL L+ WLE R E T++
Sbjct: 860 LVDRVEEVGRLHLIKQWLEDRRSEKKTDK 888
>UniRef50_Q0UXK7 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 882
Score = 81.4 bits (192), Expect = 2e-14
Identities = 43/79 (54%), Positives = 50/79 (63%), Gaps = 1/79 (1%)
Frame = +3
Query: 6 DLVLYLYRNSLQKYIEIYVQKVNPSRLPXXXXXXXXXXCAEDIIKNLIL-VVRGQFSTDE 182
DLVLYLY+ K IE+YVQ+VNP+R P C E IIK L+ V DE
Sbjct: 740 DLVLYLYKKQQFKSIEVYVQRVNPARTPAVIGGLLDVDCDESIIKGLLASVTPSSIPIDE 799
Query: 183 LVAEVEKRNRLKLLLPWLE 239
LV+EVE RNRLKLLLP+LE
Sbjct: 800 LVSEVESRNRLKLLLPFLE 818
Score = 79.4 bits (187), Expect = 8e-14
Identities = 36/58 (62%), Positives = 44/58 (75%), Gaps = 1/58 (1%)
Frame = +2
Query: 254 GSNEPATHNALAKIYIDSNNNPERFLRENQWYDSRVVGRYCEKRDPH-LACVAYERGQ 424
G+ + A +NALAKIYIDSNNNPE+FL+EN YD+ VG+YCEKRDP L + RGQ
Sbjct: 824 GNQQQAVYNALAKIYIDSNNNPEKFLKENDQYDTLSVGKYCEKRDPQSLLSLRMRRGQ 881
>UniRef50_A7AVF3 Cluster: Clathrin heavy chain; n=1; Babesia
bovis|Rep: Clathrin heavy chain - Babesia bovis
Length = 1676
Score = 76.6 bits (180), Expect = 6e-13
Identities = 33/82 (40%), Positives = 48/82 (58%)
Frame = +2
Query: 254 GSNEPATHNALAKIYIDSNNNPERFLRENQWYDSRVVGRYCEKRDPHLACVAYERGQCDR 433
G E H ALAKI + S + E+FL N+ YD ++GR+CE RDP LA + Y Q D
Sbjct: 910 GHKETEIHTALAKIRVSSQKDAEQFLSTNKIYDRSIIGRFCEDRDPMLAYLVYSEAQLDS 969
Query: 434 ELIAVCNDNSLFKTQARYLVRR 499
+++ +C N +K A Y ++R
Sbjct: 970 DVLRLCIGNGFYKMLAAYALKR 991
Score = 52.0 bits (119), Expect = 1e-05
Identities = 25/83 (30%), Positives = 43/83 (51%)
Frame = +3
Query: 6 DLVLYLYRNSLQKYIEIYVQKVNPSRLPXXXXXXXXXXCAEDIIKNLILVVRGQFSTDEL 185
+L YLYRN ++K IE+YV +NP + +E +I +++ + L
Sbjct: 827 ELTEYLYRNGMEKAIEVYVNTINPGGVATVVSTLFDLSASEHVIHSILENLHDPNGMKAL 886
Query: 186 VAEVEKRNRLKLLLPWLETRVHE 254
+ ++R++L +L WLE RV E
Sbjct: 887 IQIADERHQLLMLRDWLEKRVEE 909
>UniRef50_Q4MZN7 Cluster: Clathrin heavy chain, putative; n=1;
Theileria parva|Rep: Clathrin heavy chain, putative -
Theileria parva
Length = 1696
Score = 66.5 bits (155), Expect = 6e-10
Identities = 29/84 (34%), Positives = 50/84 (59%)
Frame = +2
Query: 254 GSNEPATHNALAKIYIDSNNNPERFLRENQWYDSRVVGRYCEKRDPHLACVAYERGQCDR 433
G E H AL KIYI ++ NPE+ L +N +Y+ V+ +YCE+ D L+ + Y G D
Sbjct: 922 GYKEEELHTALMKIYITTSQNPEQHLTDNNYYNKVVIAQYCEEIDVQLSILVYTVGGLDE 981
Query: 434 ELIAVCNDNSLFKTQARYLVRRKD 505
++I +C + L K ++L+++ +
Sbjct: 982 QMIDLCLRHQLHKQLNQFLLKKSN 1005
Score = 52.4 bits (120), Expect = 1e-05
Identities = 24/83 (28%), Positives = 46/83 (55%)
Frame = +3
Query: 6 DLVLYLYRNSLQKYIEIYVQKVNPSRLPXXXXXXXXXXCAEDIIKNLILVVRGQFSTDEL 185
+LV +LY N L++YI+++V +NP+ + +E +I ++ VR +
Sbjct: 839 ELVEHLYNNELREYIDVFVNSINPAAVSEVIATLLDLSASEQLINKVLATVRDPLLIKSI 898
Query: 186 VAEVEKRNRLKLLLPWLETRVHE 254
+ E+R++L +L +LE+RV E
Sbjct: 899 INISEERHQLMMLKSFLESRVRE 921
>UniRef50_Q4UBV3 Cluster: Clathrin heavy chain, putative; n=1;
Theileria annulata|Rep: Clathrin heavy chain, putative -
Theileria annulata
Length = 2068
Score = 54.4 bits (125), Expect = 3e-06
Identities = 25/82 (30%), Positives = 41/82 (50%)
Frame = +2
Query: 260 NEPATHNALAKIYIDSNNNPERFLRENQWYDSRVVGRYCEKRDPHLACVAYERGQCDREL 439
NEP H AL KIYI NPE +L N++Y + YC+ D L+ + Y+
Sbjct: 1148 NEPILHTALMKIYITLGENPEDYLINNKYYLKEEIANYCQDIDLQLSLLIYKHNSMYEHF 1207
Query: 440 IAVCNDNSLFKTQARYLVRRKD 505
I + L+K+ ++L++ +
Sbjct: 1208 IKFSLKHQLYKSLYQFLLKESN 1229
>UniRef50_Q8UUQ8 Cluster: Clathrin heavy-chain; n=15;
Eukaryota|Rep: Clathrin heavy-chain - Gallus gallus
(Chicken)
Length = 40
Score = 45.6 bits (103), Expect = 0.001
Identities = 20/21 (95%), Positives = 21/21 (100%)
Frame = +3
Query: 6 DLVLYLYRNSLQKYIEIYVQK 68
DLVLYLYRN+LQKYIEIYVQK
Sbjct: 20 DLVLYLYRNNLQKYIEIYVQK 40
>UniRef50_P74408 Cluster: Slr0286 protein; n=1; Synechocystis sp.
PCC 6803|Rep: Slr0286 protein - Synechocystis sp.
(strain PCC 6803)
Length = 426
Score = 37.9 bits (84), Expect = 0.25
Identities = 22/60 (36%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Frame = +1
Query: 523 VLSEENPYKRQLIDQVVQTALSETQDPEDISVT-VKAFMTADLPNELIELLEKIVPDNSV 699
V+ ++ P K+QLI QV Q+ D I T +K + A L EL+ LEKI+ D+ +
Sbjct: 74 VIQQKFPIKKQLIQQVSQSFRLIDHDGYKIECTGIKTSIFAKLETELVHFLEKIIADSGL 133
>UniRef50_UPI0000ECD20F Cluster: DJ-1-binding protein (CAP-binding
protein complex-interacting protein 1).; n=2; Gallus
gallus|Rep: DJ-1-binding protein (CAP-binding protein
complex-interacting protein 1). - Gallus gallus
Length = 171
Score = 34.3 bits (75), Expect = 3.0
Identities = 21/67 (31%), Positives = 33/67 (49%)
Frame = +2
Query: 188 C*SGKEE*TETPPSLAGNKST*GSNEPATHNALAKIYIDSNNNPERFLRENQWYDSRVVG 367
C S + E +TP SL G KST S+ P T A + + E +R+N R +
Sbjct: 20 CTSSQPEHPKTPSSLVGQKSTSASSRPQTTTA-CSVPVPKWEEIENKIRKNIQCSWRDIL 78
Query: 368 RYCEKRD 388
+ C+++D
Sbjct: 79 KLCQEKD 85
>UniRef50_Q8KEA6 Cluster: Putative uncharacterized protein; n=1;
Chlorobaculum tepidum|Rep: Putative uncharacterized
protein - Chlorobium tepidum
Length = 47
Score = 34.3 bits (75), Expect = 3.0
Identities = 21/45 (46%), Positives = 27/45 (60%), Gaps = 2/45 (4%)
Frame = -3
Query: 212 SIPL--FHFSNQFISRKLSPNNQDQVLNDVFSTINI*QATNYDWQ 84
SIPL FHF +Q + R LSPN ++ VFS +N A Y+WQ
Sbjct: 5 SIPLLPFHFHHQMLYRSLSPNAEEY---GVFSCLN---AETYNWQ 43
>UniRef50_A6G726 Cluster: PBS lyase HEAT-like repeat protein; n=1;
Plesiocystis pacifica SIR-1|Rep: PBS lyase HEAT-like
repeat protein - Plesiocystis pacifica SIR-1
Length = 663
Score = 33.1 bits (72), Expect = 7.0
Identities = 27/84 (32%), Positives = 40/84 (47%), Gaps = 11/84 (13%)
Frame = +1
Query: 478 GSLPGAQEGSDLWLEVLSEENPYKR--------QLID-QVVQTALSETQDPEDI--SVTV 624
G +PG EG L++E+P R QL D Q +Q L+ T DP + + V
Sbjct: 462 GQVPGEHEGVGALCFALADEDPQVRAASCRSLGQLGDTQSIQPLLAATSDPVPLVRAAAV 521
Query: 625 KAFMTADLPNELIELLEKIVPDNS 696
+A + D P + + E I+ DNS
Sbjct: 522 QALVMIDNPITMARMREIILDDNS 545
>UniRef50_Q23FZ0 Cluster: Sec1 family protein; n=1; Tetrahymena
thermophila SB210|Rep: Sec1 family protein - Tetrahymena
thermophila SB210
Length = 2209
Score = 32.7 bits (71), Expect = 9.2
Identities = 24/85 (28%), Positives = 38/85 (44%), Gaps = 7/85 (8%)
Frame = +1
Query: 478 GSLPGAQEGSDLWLEVLSEENPYKRQLIDQ-------VVQTALSETQDPEDISVTVKAFM 636
G+L G Q G + +++ SE N + DQ +V ++ E Q +D K
Sbjct: 1889 GALIGLQAGKPVLMKLSSENNTIYSSIRDQQISKSREIVTSSALELQRIKDTIQNYKQNK 1948
Query: 637 TADLPNELIELLEKIVPDNSVFSDH 711
T D + I+++EKI D DH
Sbjct: 1949 TQDDLQKCIKIVEKITKDQKHIEDH 1973
>UniRef50_O18004 Cluster: Putative uncharacterized protein fbxb-85;
n=1; Caenorhabditis elegans|Rep: Putative
uncharacterized protein fbxb-85 - Caenorhabditis elegans
Length = 286
Score = 32.7 bits (71), Expect = 9.2
Identities = 13/42 (30%), Positives = 26/42 (61%)
Frame = -3
Query: 254 LMYSCFQPRKEEFQSIPLFHFSNQFISRKLSPNNQDQVLNDV 129
L+ SCF PR ++FQ++ +F N I + S +D +++++
Sbjct: 145 LLLSCFSPRVQDFQAVTCCNFKNIMIKQDESIKLEDLLVSNI 186
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 670,354,497
Number of Sequences: 1657284
Number of extensions: 12885675
Number of successful extensions: 37899
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 36520
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 37875
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 57438021881
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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