BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= NV021691 (651 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_A2VCT3 Cluster: OGDH protein; n=22; Bilateria|Rep: OGDH... 159 4e-38 UniRef50_Q02218 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 159 4e-38 UniRef50_Q4SL15 Cluster: Chromosome 17 SCAF14563, whole genome s... 151 1e-35 UniRef50_A7PIZ4 Cluster: Chromosome chr13 scaffold_17, whole gen... 143 4e-33 UniRef50_Q01LD8 Cluster: OSIGBa0096P03.7 protein; n=5; Viridipla... 140 2e-32 UniRef50_UPI000051A0C7 Cluster: PREDICTED: similar to CG33791-PC... 134 2e-30 UniRef50_UPI00015B6161 Cluster: PREDICTED: hypothetical protein;... 131 2e-29 UniRef50_Q54JE4 Cluster: Putative uncharacterized protein; n=1; ... 130 4e-29 UniRef50_Q6BKY7 Cluster: Similar to CA3149|CaKGD1 Candida albica... 128 2e-28 UniRef50_UPI0000DAE34D Cluster: hypothetical protein Rgryl_01000... 122 1e-26 UniRef50_Q4Q171 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 121 2e-26 UniRef50_Q1CZK3 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 118 9e-26 UniRef50_P20967 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 117 2e-25 UniRef50_A6DL94 Cluster: Alpha-ketoglutarate decarboxylase; n=1;... 117 3e-25 UniRef50_Q3JEV2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 115 9e-25 UniRef50_Q14JZ4 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 115 1e-24 UniRef50_Q11PR5 Cluster: Oxoglutarate dehydrogenase (Succinyl-tr... 115 1e-24 UniRef50_Q74B13 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 113 3e-24 UniRef50_A4S835 Cluster: Predicted protein; n=1; Ostreococcus lu... 113 3e-24 UniRef50_Q5NYB8 Cluster: 2-oxoglutarate dehydrogenase complex, E... 113 5e-24 UniRef50_Q01VQ8 Cluster: 2-oxoglutarate dehydrogenase, E1 subuni... 112 6e-24 UniRef50_Q5PB66 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 112 8e-24 UniRef50_Q2S3D2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 111 1e-23 UniRef50_Q7UM46 Cluster: Alpha-ketoglutarate dehydrogenase E1; n... 111 2e-23 UniRef50_A6GF68 Cluster: Alpha-ketoglutarate decarboxylase; n=1;... 110 2e-23 UniRef50_Q00UK1 Cluster: Predicted 2-oxoglutarate dehydrogenase,... 110 2e-23 UniRef50_P51056 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 110 2e-23 UniRef50_Q8YJE4 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 110 2e-23 UniRef50_UPI00006CD2E0 Cluster: 2-oxoglutarate dehydrogenase, E1... 110 3e-23 UniRef50_Q12AA2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 110 3e-23 UniRef50_A7BE99 Cluster: Putative uncharacterized protein; n=1; ... 109 4e-23 UniRef50_A5EW58 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 109 4e-23 UniRef50_Q9RXM3 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 109 6e-23 UniRef50_P20707 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 109 6e-23 UniRef50_A5K5P2 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 108 1e-22 UniRef50_Q9PD29 Cluster: Oxoglutarate dehydrogenase; n=17; Bacte... 108 1e-22 UniRef50_A3ZXH0 Cluster: Alpha-ketoglutarate dehydrogenase E1; n... 107 2e-22 UniRef50_P45303 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 107 3e-22 UniRef50_Q23MM6 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 106 4e-22 UniRef50_A0DG23 Cluster: Chromosome undetermined scaffold_5, who... 106 4e-22 UniRef50_Q6BGE2 Cluster: 2-oxoglutarate dehydrogenase, putative;... 105 9e-22 UniRef50_Q7WRM3 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 105 9e-22 UniRef50_Q8F6S7 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 105 9e-22 UniRef50_Q1R3M6 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 105 1e-21 UniRef50_Q5FSJ1 Cluster: 2-Oxoglutarate dehydrogenase E1 compone... 104 2e-21 UniRef50_Q057P3 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 104 2e-21 UniRef50_Q8NRC3 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 103 3e-21 UniRef50_Q2GDI7 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 103 4e-21 UniRef50_Q387A7 Cluster: 2-oxoglutarate dehydrogenase subunit, p... 102 6e-21 UniRef50_Q8K9N3 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 101 1e-20 UniRef50_A7H8J4 Cluster: 2-oxoglutarate dehydrogenase, E1 subuni... 101 2e-20 UniRef50_A7CWX7 Cluster: Oxoglutarate dehydrogenase; n=1; Opitut... 101 2e-20 UniRef50_UPI0000E46CA4 Cluster: PREDICTED: hypothetical protein,... 100 3e-20 UniRef50_A3IFN6 Cluster: Alpha-ketoglutarate decarboxylase; n=1;... 100 3e-20 UniRef50_Q6MC85 Cluster: Probable 2-oxoglutarate dehydrogenase E... 100 6e-20 UniRef50_Q23KH1 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 99 8e-20 UniRef50_A4CGF1 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 99 1e-19 UniRef50_Q81TK1 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 99 1e-19 UniRef50_Q1IKU2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 98 2e-19 UniRef50_Q4UKI8 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 98 2e-19 UniRef50_A0FRW7 Cluster: 2-oxoglutarate dehydrogenase, E1 subuni... 97 3e-19 UniRef50_Q5L172 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 96 6e-19 UniRef50_Q7VR91 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 95 2e-18 UniRef50_Q4RSE1 Cluster: Chromosome 13 SCAF15000, whole genome s... 94 2e-18 UniRef50_Q96HY7 Cluster: Dehydrogenase E1 and transketolase doma... 93 4e-18 UniRef50_Q5L672 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 93 7e-18 UniRef50_Q8IGV6 Cluster: RE22749p; n=7; Diptera|Rep: RE22749p - ... 91 2e-17 UniRef50_A5CEI8 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 91 2e-17 UniRef50_Q23629 Cluster: Putative uncharacterized protein; n=3; ... 89 6e-17 UniRef50_A7AW62 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 89 6e-17 UniRef50_Q6MJP2 Cluster: Oxoglutarate dehydrogenase; n=1; Bdello... 87 5e-16 UniRef50_Q54VG0 Cluster: Oxoglutarate dehydrogenase; n=1; Dictyo... 86 6e-16 UniRef50_A0BCX8 Cluster: Chromosome undetermined scaffold_10, wh... 86 6e-16 UniRef50_Q4MZ92 Cluster: 2-oxoglutarate dehydrogenase e1 compone... 76 8e-13 UniRef50_Q2UQN4 Cluster: RIB40 genomic DNA, SC005; n=1; Aspergil... 69 7e-11 UniRef50_A2QL94 Cluster: Contig An06c0020, complete genome; n=2;... 68 2e-10 UniRef50_Q675U8 Cluster: CG1544-PA-like protein; n=1; Oikopleura... 61 3e-08 UniRef50_Q9RYC1 Cluster: 2-oxo acid dehydrogenase, E1 component,... 47 5e-04 UniRef50_Q50992 Cluster: SucA protein; n=3; Neisseria|Rep: SucA ... 42 0.013 UniRef50_Q835M4 Cluster: Pyruvate dehydrogenase complex E1 compo... 38 0.28 UniRef50_Q9KJ66 Cluster: Irb5; n=1; Vibrio cholerae|Rep: Irb5 - ... 38 0.28 UniRef50_Q24678 Cluster: Nucleic acid binding protein; n=1; Gira... 38 0.28 UniRef50_A0DHF2 Cluster: Chromosome undetermined scaffold_50, wh... 37 0.48 UniRef50_Q5KBR1 Cluster: Putative uncharacterized protein; n=1; ... 36 0.84 UniRef50_A7SMY1 Cluster: Predicted protein; n=1; Nematostella ve... 36 1.1 UniRef50_Q3JSC1 Cluster: Putative uncharacterized protein; n=4; ... 35 1.5 UniRef50_A3Z1Y0 Cluster: Serine protease, subtilase family prote... 35 1.5 UniRef50_Q7RDV5 Cluster: PWI domain, putative; n=3; Plasmodium (... 35 1.9 UniRef50_Q96BV0 Cluster: Zinc finger protein 775; n=3; Homo/Pan/... 35 1.9 UniRef50_UPI0000F1FF18 Cluster: PREDICTED: hypothetical protein;... 34 2.6 UniRef50_Q11BT2 Cluster: Putative uncharacterized protein; n=1; ... 34 2.6 UniRef50_Q0JN66 Cluster: Os01g0323600 protein; n=1; Oryza sativa... 34 2.6 UniRef50_A4HMC2 Cluster: Putative uncharacterized protein; n=3; ... 34 2.6 UniRef50_UPI0000D578E3 Cluster: PREDICTED: similar to Hypothetic... 34 3.4 UniRef50_A1GDX9 Cluster: Peptidyl-prolyl cis-trans isomerase; n=... 34 3.4 UniRef50_Q7S6B5 Cluster: Putative uncharacterized protein NCU071... 34 3.4 UniRef50_Q2GW32 Cluster: Putative uncharacterized protein; n=1; ... 34 3.4 UniRef50_Q0CBK4 Cluster: Putative uncharacterized protein; n=1; ... 34 3.4 UniRef50_Q4PHA6 Cluster: Mediator of RNA polymerase II transcrip... 34 3.4 UniRef50_Q8TA29 Cluster: Putative pyruvate dehydrogenase; n=1; H... 33 4.5 UniRef50_Q19854 Cluster: Putative uncharacterized protein; n=2; ... 33 4.5 UniRef50_Q3JV89 Cluster: Putative uncharacterized protein; n=6; ... 33 5.9 UniRef50_A0JY86 Cluster: Putative uncharacterized protein; n=2; ... 33 5.9 UniRef50_Q62KZ5 Cluster: Putative uncharacterized protein; n=5; ... 33 7.8 UniRef50_Q5H6J7 Cluster: Xylose repressor-like protein; n=6; Xan... 33 7.8 UniRef50_Q1YEG0 Cluster: Putative uncharacterized protein; n=1; ... 33 7.8 UniRef50_Q9C8M7 Cluster: Peptidyl-prolyl cis-trans isomerase; n=... 33 7.8 UniRef50_Q69XY6 Cluster: Putative uncharacterized protein P0633D... 33 7.8 UniRef50_Q01D15 Cluster: Chromosome 03 contig 1, DNA sequence; n... 33 7.8 UniRef50_A7S8G5 Cluster: Predicted protein; n=1; Nematostella ve... 33 7.8 UniRef50_Q05738 Cluster: Sex-determining region Y protein; n=35;... 33 7.8 >UniRef50_A2VCT3 Cluster: OGDH protein; n=22; Bilateria|Rep: OGDH protein - Homo sapiens (Human) Length = 640 Score = 159 bits (387), Expect = 4e-38 Identities = 69/85 (81%), Positives = 78/85 (91%) Frame = +2 Query: 254 DLPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVC 433 DLP+YTTHGT+H+V NNQIGFTTDPR +RSS Y TDVARVVNAPIFHVN D+PEAVM+VC Sbjct: 334 DLPSYTTHGTVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNSDDPEAVMYVC 393 Query: 434 NVAAEWRATFHKDVVIDIVSYRRNG 508 VAAEWR+TFHKDVV+D+V YRRNG Sbjct: 394 KVAAEWRSTFHKDVVVDLVCYRRNG 418 Score = 145 bits (351), Expect = 9e-34 Identities = 66/84 (78%), Positives = 74/84 (88%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 182 SGDVKYHLG Y R+NRVT++NI L++ ANPSHLEA DPVV GKT+AEQFY GD EGKKV Sbjct: 250 SGDVKYHLGMYHRRINRVTDRNITLSLVANPSHLEAADPVVMGKTKAEQFYCGDTEGKKV 309 Query: 183 MSILLHGDAAFAGQGVVFETMHLS 254 MSILLHGDAAFAGQG+V+ET HLS Sbjct: 310 MSILLHGDAAFAGQGIVYETFHLS 333 Score = 67.3 bits (157), Expect = 3e-10 Identities = 28/45 (62%), Positives = 39/45 (86%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKD 642 +NE+DEPMFTQPLMY++IRK KPVL+KYA+ L+++GVV E ++ Sbjct: 419 HNEMDEPMFTQPLMYKQIRKQKPVLQKYAELLVSQGVVNQPEYEE 463 >UniRef50_Q02218 Cluster: 2-oxoglutarate dehydrogenase E1 component, mitochondrial precursor; n=77; Eumetazoa|Rep: 2-oxoglutarate dehydrogenase E1 component, mitochondrial precursor - Homo sapiens (Human) Length = 1002 Score = 159 bits (387), Expect = 4e-38 Identities = 69/85 (81%), Positives = 78/85 (91%) Frame = +2 Query: 254 DLPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVC 433 DLP+YTTHGT+H+V NNQIGFTTDPR +RSS Y TDVARVVNAPIFHVN D+PEAVM+VC Sbjct: 428 DLPSYTTHGTVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNSDDPEAVMYVC 487 Query: 434 NVAAEWRATFHKDVVIDIVSYRRNG 508 VAAEWR+TFHKDVV+D+V YRRNG Sbjct: 488 KVAAEWRSTFHKDVVVDLVCYRRNG 512 Score = 145 bits (351), Expect = 9e-34 Identities = 66/84 (78%), Positives = 74/84 (88%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 182 SGDVKYHLG Y R+NRVT++NI L++ ANPSHLEA DPVV GKT+AEQFY GD EGKKV Sbjct: 344 SGDVKYHLGMYHRRINRVTDRNITLSLVANPSHLEAADPVVMGKTKAEQFYCGDTEGKKV 403 Query: 183 MSILLHGDAAFAGQGVVFETMHLS 254 MSILLHGDAAFAGQG+V+ET HLS Sbjct: 404 MSILLHGDAAFAGQGIVYETFHLS 427 Score = 67.3 bits (157), Expect = 3e-10 Identities = 28/45 (62%), Positives = 39/45 (86%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKD 642 +NE+DEPMFTQPLMY++IRK KPVL+KYA+ L+++GVV E ++ Sbjct: 513 HNEMDEPMFTQPLMYKQIRKQKPVLQKYAELLVSQGVVNQPEYEE 557 >UniRef50_Q4SL15 Cluster: Chromosome 17 SCAF14563, whole genome shotgun sequence; n=4; Clupeocephala|Rep: Chromosome 17 SCAF14563, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1054 Score = 151 bits (366), Expect = 1e-35 Identities = 70/84 (83%), Positives = 77/84 (91%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 182 SGDVKYHLG Y ER+NR T+KNI L++ ANPSHLEAVDPVVQGKT+AEQFYRGD EGKKV Sbjct: 343 SGDVKYHLGMYHERINRKTDKNITLSLVANPSHLEAVDPVVQGKTKAEQFYRGDVEGKKV 402 Query: 183 MSILLHGDAAFAGQGVVFETMHLS 254 MSIL+HGDAAFAGQGVV+ET HLS Sbjct: 403 MSILIHGDAAFAGQGVVYETFHLS 426 Score = 121 bits (292), Expect = 1e-26 Identities = 66/112 (58%), Positives = 79/112 (70%), Gaps = 27/112 (24%) Frame = +2 Query: 254 DLPAYTTHGTIHI-----VANN----------------------QIGFTTDPRHSRSSAY 352 +LP+YTTHGTIH+ V+N+ QIGFTTDPR +RSS Y Sbjct: 427 ELPSYTTHGTIHVVVNNQVSNSPPSVMQFRHFEEGQRKAVMVAPQIGFTTDPRVARSSPY 486 Query: 353 CTDVARVVNAPIFHVNGDNPEAVMHVCNVAAEWRATFHKDVVIDIVSYRRNG 508 TDVARVVNAPIFHVN D+PEAV++VC +AAEWR+TF+KDVVID+VSYRR G Sbjct: 487 PTDVARVVNAPIFHVNADDPEAVVYVCQIAAEWRSTFNKDVVIDLVSYRRFG 538 Score = 66.5 bits (155), Expect = 5e-10 Identities = 29/45 (64%), Positives = 39/45 (86%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKD 642 +NE+DEPMFTQPLMY+ IR+ + VL+KY+D LIAEGVVT +E ++ Sbjct: 539 HNEMDEPMFTQPLMYKLIRRQEHVLKKYSDHLIAEGVVTLQEYEE 583 >UniRef50_A7PIZ4 Cluster: Chromosome chr13 scaffold_17, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr13 scaffold_17, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 973 Score = 143 bits (346), Expect = 4e-33 Identities = 62/84 (73%), Positives = 70/84 (83%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCN 436 LP YTT GTIHIV NNQ+ FTTDPR RSS YCTDVA+ +NAPIFHVNGD+ EAV+HVC Sbjct: 388 LPNYTTGGTIHIVVNNQVAFTTDPRSGRSSQYCTDVAKALNAPIFHVNGDDMEAVVHVCE 447 Query: 437 VAAEWRATFHKDVVIDIVSYRRNG 508 +AAEWR TFH DVV+D+V YRR G Sbjct: 448 LAAEWRQTFHSDVVVDVVCYRRFG 471 Score = 109 bits (262), Expect = 6e-23 Identities = 51/84 (60%), Positives = 65/84 (77%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 182 +GDVKYHLGT +R R + I L++ ANPSHLEAVDPVV GKTRA+Q+Y D + K Sbjct: 304 TGDVKYHLGTSYDRPTR-GGRRIHLSLVANPSHLEAVDPVVVGKTRAKQYYSNDLDRTKN 362 Query: 183 MSILLHGDAAFAGQGVVFETMHLS 254 + +L+HGD +FAGQGVV+ET+HLS Sbjct: 363 IGVLIHGDGSFAGQGVVYETLHLS 386 Score = 46.0 bits (104), Expect = 8e-04 Identities = 21/48 (43%), Positives = 30/48 (62%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDVKD 651 +NE+DEP FTQP MY+ IR LE Y +L+ G T E++ V++ Sbjct: 472 HNEIDEPSFTQPKMYKVIRNHPSALEIYQKKLLELGQATQEDIDRVQN 519 >UniRef50_Q01LD8 Cluster: OSIGBa0096P03.7 protein; n=5; Viridiplantae|Rep: OSIGBa0096P03.7 protein - Oryza sativa (Rice) Length = 1016 Score = 140 bits (340), Expect = 2e-32 Identities = 62/84 (73%), Positives = 70/84 (83%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCN 436 LP YTT GTIHIV NNQ+ FTTDPR RSS YCTDVA+ ++APIFHVNGD+ EAV+HVC Sbjct: 413 LPNYTTGGTIHIVVNNQVAFTTDPRAGRSSQYCTDVAKALDAPIFHVNGDDLEAVVHVCE 472 Query: 437 VAAEWRATFHKDVVIDIVSYRRNG 508 +AAEWR TFH DVV+DIV YRR G Sbjct: 473 LAAEWRQTFHSDVVVDIVCYRRFG 496 Score = 111 bits (267), Expect = 1e-23 Identities = 52/84 (61%), Positives = 66/84 (78%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 182 +GDVKYHLGT +R R K+I L++ ANPSHLEAVDPVV GKTRA+Q+Y D + K Sbjct: 329 TGDVKYHLGTSYDRPTR-GGKHIHLSLVANPSHLEAVDPVVAGKTRAKQYYSNDLDRTKN 387 Query: 183 MSILLHGDAAFAGQGVVFETMHLS 254 + +LLHGD +F+GQGVV+ET+HLS Sbjct: 388 LGVLLHGDGSFSGQGVVYETLHLS 411 Score = 46.8 bits (106), Expect = 5e-04 Identities = 19/43 (44%), Positives = 30/43 (69%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEV 636 +NE+DEP FTQP MY+ IR + LE Y ++L+ G ++ E++ Sbjct: 497 HNEIDEPSFTQPKMYKIIRNHQSALEIYQNRLLESGKISKEDI 539 >UniRef50_UPI000051A0C7 Cluster: PREDICTED: similar to CG33791-PC, isoform C; n=1; Apis mellifera|Rep: PREDICTED: similar to CG33791-PC, isoform C - Apis mellifera Length = 980 Score = 134 bits (323), Expect = 2e-30 Identities = 60/85 (70%), Positives = 71/85 (83%) Frame = +2 Query: 254 DLPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVC 433 +LP YTT G IHIV NNQIGFTTDPR+SRSSA+CTDVARVVNAPIFH++ D+P+ V + Sbjct: 392 NLPNYTTGGVIHIVINNQIGFTTDPRYSRSSAHCTDVARVVNAPIFHIHADDPDLVTYCS 451 Query: 434 NVAAEWRATFHKDVVIDIVSYRRNG 508 VA+E+RA FH DVV+DIV YRR G Sbjct: 452 KVASEYRAEFHNDVVVDIVGYRRFG 476 Score = 117 bits (281), Expect = 3e-25 Identities = 54/85 (63%), Positives = 69/85 (81%), Gaps = 1/85 (1%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNE-GKK 179 SGDVKYHLGT+ ER+ + K IR+A+ ANPSHLEA+DPVV G+ RAEQ + D E GKK Sbjct: 307 SGDVKYHLGTHAERMLERSQKQIRVAMMANPSHLEAIDPVVVGRVRAEQVEKNDAEFGKK 366 Query: 180 VMSILLHGDAAFAGQGVVFETMHLS 254 ++ L+HGDAAF+GQG+V+ETMHL+ Sbjct: 367 SVAFLVHGDAAFSGQGIVYETMHLT 391 Score = 53.2 bits (122), Expect = 5e-06 Identities = 23/45 (51%), Positives = 33/45 (73%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKD 642 +NE+DEPM TQPLMY++I++ VL Y+D+L EGV+T K+ Sbjct: 477 HNELDEPMLTQPLMYKRIKQHPNVLNIYSDKLFKEGVITEAFAKE 521 >UniRef50_UPI00015B6161 Cluster: PREDICTED: hypothetical protein; n=1; Nasonia vitripennis|Rep: PREDICTED: hypothetical protein - Nasonia vitripennis Length = 1012 Score = 131 bits (316), Expect = 2e-29 Identities = 57/84 (67%), Positives = 69/84 (82%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCN 436 LP YTT G IH V NNQIGFTTDPR+SRSSA+CTD+ R+VNAPIFHV+ D+P+ V + Sbjct: 431 LPDYTTGGVIHSVINNQIGFTTDPRYSRSSAHCTDIGRIVNAPIFHVHADDPDLVAYCSK 490 Query: 437 VAAEWRATFHKDVVIDIVSYRRNG 508 VA+E+RA +H DVV+DIV YRRNG Sbjct: 491 VASEYRAEYHNDVVLDIVGYRRNG 514 Score = 108 bits (259), Expect = 1e-22 Identities = 48/84 (57%), Positives = 66/84 (78%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 182 SGDVKYHLGT ER+ + K + ++V ANPSHLE+VD V G+ RAEQ +GD +G+K Sbjct: 346 SGDVKYHLGTCAERVLERSGKKMHVSVTANPSHLESVDSVTVGRVRAEQVEKGDIKGQKS 405 Query: 183 MSILLHGDAAFAGQGVVFETMHLS 254 ++IL+HGDAA++GQG+ +ETMHL+ Sbjct: 406 LAILVHGDAAYSGQGICYETMHLT 429 Score = 50.4 bits (115), Expect = 4e-05 Identities = 22/48 (45%), Positives = 33/48 (68%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDVKD 651 +NE+DEPM TQPLMY++I+ VL Y D+L+ EG++ +K+ D Sbjct: 515 HNEMDEPMLTQPLMYKRIQSHPNVLAIYTDKLLKEGLIDEAFLKEETD 562 >UniRef50_Q54JE4 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 1013 Score = 130 bits (313), Expect = 4e-29 Identities = 54/85 (63%), Positives = 70/85 (82%) Frame = +2 Query: 254 DLPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVC 433 +L Y+T GT+HIV NNQIGFTT+P++SRSS YCTDVA+ ++ P+FHVNGDN EAV+ VC Sbjct: 420 NLDNYSTGGTVHIVVNNQIGFTTNPKYSRSSKYCTDVAKTIDIPVFHVNGDNVEAVVKVC 479 Query: 434 NVAAEWRATFHKDVVIDIVSYRRNG 508 +AAEWR F +DV +DIV YR++G Sbjct: 480 KIAAEWRQKFKRDVFVDIVCYRKHG 504 Score = 109 bits (261), Expect = 7e-23 Identities = 50/84 (59%), Positives = 66/84 (78%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 182 +GDVKYHLGT +R+ + K + L++ ANPSHLEAV+P+V+GK RA+Q Y D E KK Sbjct: 337 TGDVKYHLGTSYDRVTS-SGKKVHLSLVANPSHLEAVNPLVEGKVRAKQHYSKDTEQKKS 395 Query: 183 MSILLHGDAAFAGQGVVFETMHLS 254 M++ LHGDA+ AGQGVV+ET+HLS Sbjct: 396 MAVQLHGDASVAGQGVVYETLHLS 419 Score = 62.1 bits (144), Expect = 1e-08 Identities = 25/48 (52%), Positives = 38/48 (79%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDVKD 651 +NE D+P FTQP+MY KI K +P++EKY+++LIAE V+T E+ +K+ Sbjct: 505 HNETDQPKFTQPIMYDKIGKQQPIIEKYSNKLIAEKVITQEQYLQMKN 552 >UniRef50_Q6BKY7 Cluster: Similar to CA3149|CaKGD1 Candida albicans CaKGD1 2-oxoglutarate dehydrogenase; n=4; Ascomycota|Rep: Similar to CA3149|CaKGD1 Candida albicans CaKGD1 2-oxoglutarate dehydrogenase - Debaryomyces hansenii (Yeast) (Torulaspora hansenii) Length = 997 Score = 128 bits (308), Expect = 2e-28 Identities = 55/97 (56%), Positives = 74/97 (76%) Frame = +2 Query: 254 DLPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVC 433 +LP Y+T GTIHI+ NNQIGFTTDPR +RS+ Y +D+A+ +NAPIFHVN D+ EA + + Sbjct: 406 NLPDYSTGGTIHIIVNNQIGFTTDPRFARSTLYPSDIAKSINAPIFHVNADDVEANIFIF 465 Query: 434 NVAAEWRATFHKDVVIDIVSYRRNGTTKSTNRCSLSP 544 N+AAEWRATFH DV+ID+V YR++G ++ P Sbjct: 466 NLAAEWRATFHTDVIIDLVGYRKHGHNETDQPAFTQP 502 Score = 100 bits (240), Expect = 3e-20 Identities = 53/85 (62%), Positives = 63/85 (74%), Gaps = 1/85 (1%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGD-NEGKK 179 SGDVKYHLG R + K++ L++ ANPSHLE+ D VV GKTRA Q Y+ D E KK Sbjct: 322 SGDVKYHLGMNYARPT-TSGKHVNLSLVANPSHLESEDGVVLGKTRAIQQYKNDIGEYKK 380 Query: 180 VMSILLHGDAAFAGQGVVFETMHLS 254 MSILLHGDAAF+GQGVV+ETM L+ Sbjct: 381 AMSILLHGDAAFSGQGVVYETMGLA 405 Score = 60.9 bits (141), Expect = 3e-08 Identities = 26/47 (55%), Positives = 34/47 (72%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDVK 648 +NE D+P FTQPLMYQKI + KPV++ Y QLI EG T E++ + K Sbjct: 491 HNETDQPAFTQPLMYQKIAEKKPVIDYYTKQLIEEGTFTKEDIDEHK 537 >UniRef50_UPI0000DAE34D Cluster: hypothetical protein Rgryl_01000074; n=1; Rickettsiella grylli|Rep: hypothetical protein Rgryl_01000074 - Rickettsiella grylli Length = 929 Score = 122 bits (293), Expect = 1e-26 Identities = 54/94 (57%), Positives = 72/94 (76%) Frame = +2 Query: 263 AYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCNVA 442 AY T GT+HIV NNQ+GFTTDP+++RSS YCTD A++V+APIFHVN D+PEAV+ +A Sbjct: 375 AYGTGGTLHIVLNNQLGFTTDPQNARSSWYCTDPAKMVDAPIFHVNSDDPEAVLFAIQLA 434 Query: 443 AEWRATFHKDVVIDIVSYRRNGTTKSTNRCSLSP 544 ++R TF KDVVID+V YRR+G ++ + P Sbjct: 435 FDFRQTFRKDVVIDLVCYRRHGHNEADEPAATQP 468 Score = 78.2 bits (184), Expect = 2e-13 Identities = 39/84 (46%), Positives = 55/84 (65%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 182 SGDVKYH G + + + + +A+ NPSHLE V+PVV+G R+ Q R + ++V Sbjct: 290 SGDVKYHKGFAADL--KTDHGVMHVAMAFNPSHLEIVNPVVEGSVRSRQERRQEGGQQQV 347 Query: 183 MSILLHGDAAFAGQGVVFETMHLS 254 + +L+HGDAAF+GQGVV E LS Sbjct: 348 LPLLIHGDAAFSGQGVVMENFELS 371 Score = 54.0 bits (124), Expect = 3e-06 Identities = 24/48 (50%), Positives = 34/48 (70%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDVKD 651 +NE DEP TQPL+YQ I+ + ++YAD LI +G+VT+EEV+ D Sbjct: 457 HNEADEPAATQPLLYQTIKALQTPKQRYADVLIRQGIVTSEEVQRWSD 504 >UniRef50_Q4Q171 Cluster: 2-oxoglutarate dehydrogenase E1 component, putative; n=6; Trypanosomatidae|Rep: 2-oxoglutarate dehydrogenase E1 component, putative - Leishmania major Length = 979 Score = 121 bits (291), Expect = 2e-26 Identities = 59/108 (54%), Positives = 72/108 (66%), Gaps = 1/108 (0%) Frame = +2 Query: 272 THGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCNVAAEW 451 T GT+H+V NNQIGFTTDP+ SRSSAYC+D+ RV N PI HVNGD PE V+ V AAE+ Sbjct: 410 TGGTVHVVCNNQIGFTTDPKSSRSSAYCSDLGRVYNCPILHVNGDYPEEVIRVFEFAAEY 469 Query: 452 RATFHKDVVIDIVSYRRNGTTKSTNRCSLSPSCTRRF-VRPNQYWRNT 592 RA FHK VVID+V YRR G ++ + P R P+ + R T Sbjct: 470 RARFHKSVVIDLVCYRRFGHNENDDPSITQPLMYERVRAMPDVFRRYT 517 Score = 87.0 bits (206), Expect = 3e-16 Identities = 46/82 (56%), Positives = 56/82 (68%) Frame = +3 Query: 9 DVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKVMS 188 DVKYHLG Y +L + K + + NPSHLEAV+P VQG TRA Q G+ +KV+ Sbjct: 323 DVKYHLG-YRGQLKLNSGKVMETEMLFNPSHLEAVNPFVQGYTRAMQVSLGEKGREKVLP 381 Query: 189 ILLHGDAAFAGQGVVFETMHLS 254 I +HGDAAFAGQGV FETM +S Sbjct: 382 IEIHGDAAFAGQGVAFETMCIS 403 Score = 48.4 bits (110), Expect = 1e-04 Identities = 18/42 (42%), Positives = 29/42 (69%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEE 633 +NE D+P TQPLMY+++R V +Y D LI +G++T ++ Sbjct: 489 HNENDDPSITQPLMYERVRAMPDVFRRYTDALITQGILTPQQ 530 >UniRef50_Q1CZK3 Cluster: 2-oxoglutarate dehydrogenase, E1 component; n=2; Cystobacterineae|Rep: 2-oxoglutarate dehydrogenase, E1 component - Myxococcus xanthus (strain DK 1622) Length = 963 Score = 118 bits (285), Expect = 9e-26 Identities = 50/84 (59%), Positives = 65/84 (77%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCN 436 L YTT GT+H+V NNQ+GFTTDP SRSS Y T +A++++ P+FHVNGD+PEA +H+ Sbjct: 392 LKGYTTGGTVHVVINNQVGFTTDPHDSRSSLYSTAIAQMLDIPVFHVNGDDPEACVHIAK 451 Query: 437 VAAEWRATFHKDVVIDIVSYRRNG 508 + AE+R TF DVVID+V YRR G Sbjct: 452 LVAEYRQTFKSDVVIDLVCYRRYG 475 Score = 95.9 bits (228), Expect = 7e-19 Identities = 47/83 (56%), Positives = 59/83 (71%) Frame = +3 Query: 6 GDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKVM 185 GDVKYH+G + R K + L++ NPSHLEAVDPVV+G+ RA+Q GD E VM Sbjct: 309 GDVKYHMGFSSDHTTRQGRK-LHLSLAFNPSHLEAVDPVVEGRVRAKQDRGGDTERTSVM 367 Query: 186 SILLHGDAAFAGQGVVFETMHLS 254 +L+HGDAAF GQGVV ET++LS Sbjct: 368 PLLIHGDAAFIGQGVVAETLNLS 390 Score = 44.0 bits (99), Expect = 0.003 Identities = 22/47 (46%), Positives = 28/47 (59%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDVK 648 +NE DEP FTQP MY IRK V YA +L + + AEE + +K Sbjct: 476 HNEGDEPSFTQPAMYDIIRKHPTVRTLYAAKLAEQNKIPAEESEAIK 522 >UniRef50_P20967 Cluster: 2-oxoglutarate dehydrogenase E1 component, mitochondrial precursor; n=34; Fungi/Metazoa group|Rep: 2-oxoglutarate dehydrogenase E1 component, mitochondrial precursor - Saccharomyces cerevisiae (Baker's yeast) Length = 1014 Score = 117 bits (282), Expect = 2e-25 Identities = 49/104 (47%), Positives = 73/104 (70%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCN 436 LP Y+T GTIH++ NNQIGFTTDPR +RS+ Y +D+A+ ++APIFHVN ++ EAV + N Sbjct: 424 LPEYSTGGTIHVITNNQIGFTTDPRFARSTPYPSDLAKAIDAPIFHVNANDVEAVTFIFN 483 Query: 437 VAAEWRATFHKDVVIDIVSYRRNGTTKSTNRCSLSPSCTRRFVR 568 +AAEWR FH D +ID+V +R++G ++ P ++ + Sbjct: 484 LAAEWRHKFHTDAIIDVVGWRKHGHNETDQPSFTQPLMYKKIAK 527 Score = 92.7 bits (220), Expect = 7e-18 Identities = 48/86 (55%), Positives = 59/86 (68%), Gaps = 1/86 (1%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGD-NEGKK 179 SGDVKYHLG +R + K + L++ ANPSHLE+ DPVV G+TRA + D E K Sbjct: 339 SGDVKYHLGMNYQRPT-TSGKYVNLSLVANPSHLESQDPVVLGRTRALLHAKNDLKEKTK 397 Query: 180 VMSILLHGDAAFAGQGVVFETMHLST 257 + +LLHGDAAFAGQGVV+ETM T Sbjct: 398 ALGVLLHGDAAFAGQGVVYETMGFLT 423 Score = 54.8 bits (126), Expect = 2e-06 Identities = 22/47 (46%), Positives = 35/47 (74%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDVK 648 +NE D+P FTQPLMY+KI K K V++ Y ++LI+EG + +++ + K Sbjct: 508 HNETDQPSFTQPLMYKKIAKQKSVIDVYTEKLISEGTFSKKDIDEHK 554 >UniRef50_A6DL94 Cluster: Alpha-ketoglutarate decarboxylase; n=1; Lentisphaera araneosa HTCC2155|Rep: Alpha-ketoglutarate decarboxylase - Lentisphaera araneosa HTCC2155 Length = 913 Score = 117 bits (281), Expect = 3e-25 Identities = 50/85 (58%), Positives = 64/85 (75%) Frame = +2 Query: 254 DLPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVC 433 +L Y T GT+H+V NNQ+GFT + R SRSS YCTD+A+V+N+P+FHVN D+PEAV+H C Sbjct: 347 NLDGYGTGGTVHVVLNNQVGFTANYRESRSSLYCTDIAKVLNSPVFHVNADDPEAVVHAC 406 Query: 434 NVAAEWRATFHKDVVIDIVSYRRNG 508 A E R F DV IDI+ YRR+G Sbjct: 407 TTAIELRQKFACDVYIDILGYRRHG 431 Score = 79.8 bits (188), Expect = 5e-14 Identities = 37/83 (44%), Positives = 58/83 (69%) Frame = +3 Query: 6 GDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKVM 185 GDVKYH+G + + N + L++ ANPSHLEAV+PVV G+ RA+ +N+ K++ Sbjct: 265 GDVKYHMGHSADVVTEDGNP-LHLSLAANPSHLEAVNPVVLGRVRAKIEELYENDPNKIV 323 Query: 186 SILLHGDAAFAGQGVVFETMHLS 254 IL+HGDAA +GQG+++E +++ Sbjct: 324 PILVHGDAAISGQGIIYEICNMA 346 Score = 42.7 bits (96), Expect = 0.007 Identities = 19/46 (41%), Positives = 27/46 (58%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDV 645 +NE DEP FTQPL+Y I K VL+ Y +L+ G + +E + Sbjct: 432 HNEGDEPRFTQPLLYNAITKHPTVLDMYIKRLVNGGEIIEKEASGI 477 >UniRef50_Q3JEV2 Cluster: 2-oxoglutarate dehydrogenase, E1 component; n=2; Proteobacteria|Rep: 2-oxoglutarate dehydrogenase, E1 component - Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848) Length = 940 Score = 115 bits (277), Expect = 9e-25 Identities = 54/94 (57%), Positives = 69/94 (73%), Gaps = 1/94 (1%) Frame = +2 Query: 266 YTTHGTIHIVANNQIGFTT-DPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCNVA 442 + T GT+HIV NNQIGFTT +P +RS+ YCTDVA++V APIFHVNGD+PEAV+ V +A Sbjct: 380 FFTGGTLHIVINNQIGFTTSNPLDTRSTVYCTDVAKMVQAPIFHVNGDDPEAVIFVTRLA 439 Query: 443 AEWRATFHKDVVIDIVSYRRNGTTKSTNRCSLSP 544 ++R TF KDVVID+V YRR G ++ P Sbjct: 440 LDYRMTFKKDVVIDLVCYRRQGHNEADEPAVTQP 473 Score = 85.8 bits (203), Expect = 8e-16 Identities = 42/84 (50%), Positives = 55/84 (65%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 182 SGDVKYHLG + + + + NPSHLE +DPVV+G RA Q R D G +V Sbjct: 294 SGDVKYHLGFSAD--GDTPGGPVHITLAFNPSHLEIIDPVVEGSVRARQQRRKDWLGDEV 351 Query: 183 MSILLHGDAAFAGQGVVFETMHLS 254 + +L+HGD+AFAGQGVV ET ++S Sbjct: 352 IPVLIHGDSAFAGQGVVMETFNMS 375 Score = 50.8 bits (116), Expect = 3e-05 Identities = 22/42 (52%), Positives = 29/42 (69%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEE 633 +NE DEP TQPLMYQKIR V YA++L A+ ++ +EE Sbjct: 462 HNEADEPAVTQPLMYQKIRSHPTVRHLYAERLAAQNIIASEE 503 >UniRef50_Q14JZ4 Cluster: 2-oxoglutarate dehydrogenase E1 component; n=11; Francisella tularensis|Rep: 2-oxoglutarate dehydrogenase E1 component - Francisella tularensis subsp. tularensis (strain FSC 198) Length = 941 Score = 115 bits (276), Expect = 1e-24 Identities = 54/96 (56%), Positives = 70/96 (72%), Gaps = 2/96 (2%) Frame = +2 Query: 263 AYTTHGTIHIVANNQIGFTTDPRH--SRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCN 436 AY T GTIH+V NNQ+GFTT +RSS Y TDVA++V+APIFHVNGD+PEAV+ V + Sbjct: 381 AYGTGGTIHLVVNNQVGFTTSSAFGVNRSSNYSTDVAKMVDAPIFHVNGDDPEAVLKVTD 440 Query: 437 VAAEWRATFHKDVVIDIVSYRRNGTTKSTNRCSLSP 544 +A E+R F+KD+VID+V YRRNG ++ P Sbjct: 441 IALEYRMKFNKDIVIDLVCYRRNGHNETDEPSGTQP 476 Score = 83.8 bits (198), Expect = 3e-15 Identities = 42/84 (50%), Positives = 53/84 (63%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 182 SGDVKYH+G + K ++A+ NPSHLEAVDPVV+G +A Q + KV Sbjct: 296 SGDVKYHMG--YSNYRSIDGKEAKIALAFNPSHLEAVDPVVEGAAKAIQDKLDGDVYSKV 353 Query: 183 MSILLHGDAAFAGQGVVFETMHLS 254 + IL+HGD+AF GQGVV ET S Sbjct: 354 LPILIHGDSAFCGQGVVMETFGFS 377 Score = 48.4 bits (110), Expect = 1e-04 Identities = 22/41 (53%), Positives = 29/41 (70%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAE 630 +NE DEP TQP MY+ I+K L+ Y+D+LI EGVV A+ Sbjct: 465 HNETDEPSGTQPQMYEVIKKLPSTLKLYSDKLIKEGVVDAD 505 >UniRef50_Q11PR5 Cluster: Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component; n=4; Bacteroidetes|Rep: Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component - Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469) Length = 946 Score = 115 bits (276), Expect = 1e-24 Identities = 51/88 (57%), Positives = 66/88 (75%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCN 436 L Y T GTIH V NNQ+GFTTD +RSS YCTDVA++V+AP+ HVNGD+PEAV Sbjct: 380 LAGYQTGGTIHFVINNQVGFTTDFEDARSSIYCTDVAKIVDAPVMHVNGDDPEAVTFCMR 439 Query: 437 VAAEWRATFHKDVVIDIVSYRRNGTTKS 520 +AAE+R F++D+ ID+V YRR+G +S Sbjct: 440 LAAEYRQKFNEDIFIDMVCYRRHGHNES 467 Score = 78.2 bits (184), Expect = 2e-13 Identities = 40/83 (48%), Positives = 53/83 (63%) Frame = +3 Query: 6 GDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKVM 185 GDVKYH+G Y + + I L + NPSHLEAVDPVV G RA+ + KKV+ Sbjct: 297 GDVKYHMG-YSSEVVTPKGQKINLKLMPNPSHLEAVDPVVLGFVRAKGDRLYGYDYKKVL 355 Query: 186 SILLHGDAAFAGQGVVFETMHLS 254 +L+HGDAA A QG+V+E + +S Sbjct: 356 PVLIHGDAAVAAQGIVYEIVQMS 378 Score = 38.7 bits (86), Expect = 0.12 Identities = 20/46 (43%), Positives = 26/46 (56%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDV 645 +NE DEP FTQP +Y I + E Y +LI G V AE K++ Sbjct: 464 HNESDEPKFTQPKLYNVISRHANPRELYNQKLIERGDVDAEIAKNM 509 >UniRef50_Q74B13 Cluster: 2-oxoglutarate dehydrogenase, E1 component; n=8; Deltaproteobacteria|Rep: 2-oxoglutarate dehydrogenase, E1 component - Geobacter sulfurreducens Length = 894 Score = 113 bits (272), Expect = 3e-24 Identities = 49/84 (58%), Positives = 65/84 (77%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCN 436 L Y T GT+HIV NNQIGFTT P +RSS Y TD A++V AP+FHV+G++PEA +HV Sbjct: 344 LEGYRTGGTLHIVINNQIGFTTVPADARSSLYATDTAKIVAAPVFHVHGEDPEAAVHVME 403 Query: 437 VAAEWRATFHKDVVIDIVSYRRNG 508 +A E+R TF +DVV++I+ YRR+G Sbjct: 404 LALEYRQTFGRDVVVEIICYRRHG 427 Score = 92.7 bits (220), Expect = 7e-18 Identities = 46/83 (55%), Positives = 58/83 (69%) Frame = +3 Query: 6 GDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKVM 185 GDVKYH G +R +I L + NPSHLEAV+PVV+GK RA Q RG ++V+ Sbjct: 261 GDVKYHKGFSSDR-RFADGSSIHLTLAFNPSHLEAVNPVVEGKCRARQDARGPGGDRRVL 319 Query: 186 SILLHGDAAFAGQGVVFETMHLS 254 +L+HGDAAFAGQGVV ET++LS Sbjct: 320 PVLIHGDAAFAGQGVVAETLNLS 342 Score = 48.8 bits (111), Expect = 1e-04 Identities = 22/37 (59%), Positives = 27/37 (72%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGV 618 +NE DEP FTQP+MY +I+ PV E YAD+L EGV Sbjct: 428 HNEGDEPYFTQPVMYGRIKDRPPVHELYADRLAEEGV 464 >UniRef50_A4S835 Cluster: Predicted protein; n=1; Ostreococcus lucimarinus CCE9901|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 730 Score = 113 bits (272), Expect = 3e-24 Identities = 53/102 (51%), Positives = 70/102 (68%) Frame = +2 Query: 254 DLPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVC 433 DLP YTT GT+H+V NNQIGFTT PR +RSS + +DVA+ API HVNGD+P+AV+ Sbjct: 125 DLPDYTTGGTVHVVVNNQIGFTTVPRRARSSPHPSDVAKAYGAPIIHVNGDDPDAVVSAM 184 Query: 434 NVAAEWRATFHKDVVIDIVSYRRNGTTKSTNRCSLSPSCTRR 559 +AA++RA F DVV++ V YRR G + + P +RR Sbjct: 185 RLAADYRAEFQSDVVVNYVCYRRFGHNELDDPSITLPLMSRR 226 Score = 62.1 bits (144), Expect = 1e-08 Identities = 39/89 (43%), Positives = 49/89 (55%), Gaps = 7/89 (7%) Frame = +3 Query: 6 GDVKYHLGT--YIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYR-GDNEGK 176 GDV+YHLG ++ K + L + NPSHLE V+ VV G RA+QF R EG Sbjct: 35 GDVRYHLGARAVVDVDVERGAKQVALTLVPNPSHLEMVNAVVSGVVRAKQFKRDSQTEGA 94 Query: 177 K----VMSILLHGDAAFAGQGVVFETMHL 251 V+ +LLHGDA+F G G E M L Sbjct: 95 SARAHVLPLLLHGDASFCGLGQNGEVMQL 123 Score = 47.6 bits (108), Expect = 3e-04 Identities = 19/47 (40%), Positives = 33/47 (70%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDVK 648 +NE+D+P T PLM ++I T V E YA+ +AEG+++ +E+ D++ Sbjct: 210 HNELDDPSITLPLMSRRIEATPRVAENYANACVAEGILSKDELDDLR 256 >UniRef50_Q5NYB8 Cluster: 2-oxoglutarate dehydrogenase complex, E1 component; n=7; Bacteria|Rep: 2-oxoglutarate dehydrogenase complex, E1 component - Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) Length = 942 Score = 113 bits (271), Expect = 5e-24 Identities = 55/99 (55%), Positives = 66/99 (66%), Gaps = 1/99 (1%) Frame = +2 Query: 266 YTTHGTIHIVANNQIGFTT-DPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCNVA 442 Y T GT+HIV NNQIGFTT DPR RSS YCTD+ ++V APIFHVNGD+PEAV +A Sbjct: 377 YGTGGTVHIVVNNQIGFTTSDPRDYRSSLYCTDIFKMVEAPIFHVNGDDPEAVAFATALA 436 Query: 443 AEWRATFHKDVVIDIVSYRRNGTTKSTNRCSLSPSCTRR 559 E+R F KDVV+DIV YR+ G + P R+ Sbjct: 437 VEFRQEFKKDVVVDIVCYRKLGHNEQDEPMVTQPLMYRK 475 Score = 74.1 bits (174), Expect = 3e-12 Identities = 37/84 (44%), Positives = 53/84 (63%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 182 +GDVKYHLG + ++ + L + NPSHLE ++PVV+G A Q R D +V Sbjct: 291 AGDVKYHLGFSSDVMS--PGGPVHLTLSFNPSHLEIINPVVEGSVYARQLRRKDEAKSQV 348 Query: 183 MSILLHGDAAFAGQGVVFETMHLS 254 +++L+HGDAA AGQGV E ++ S Sbjct: 349 IAVLIHGDAAVAGQGVNQEMLNFS 372 Score = 47.6 bits (108), Expect = 3e-04 Identities = 24/49 (48%), Positives = 30/49 (61%), Gaps = 1/49 (2%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGV-VTAEEVKDVKD 651 +NE DEPM TQPLMY+KI + YAD+L+ EG E K +KD Sbjct: 459 HNEQDEPMVTQPLMYRKIASHPGTRKLYADRLVTEGTCAPGEPEKMIKD 507 >UniRef50_Q01VQ8 Cluster: 2-oxoglutarate dehydrogenase, E1 subunit; n=2; Bacteria|Rep: 2-oxoglutarate dehydrogenase, E1 subunit - Solibacter usitatus (strain Ellin6076) Length = 1220 Score = 112 bits (270), Expect = 6e-24 Identities = 53/101 (52%), Positives = 68/101 (67%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCN 436 L Y+T GTIH++ NNQIGFTT P SRS+ Y TDVAR V APIFHVNGD+PEA + V Sbjct: 641 LEGYSTGGTIHLIINNQIGFTTLPDESRSTPYSTDVARGVQAPIFHVNGDDPEAAIRVVQ 700 Query: 437 VAAEWRATFHKDVVIDIVSYRRNGTTKSTNRCSLSPSCTRR 559 +A ++R F DVVID++ YRR+G + + P R+ Sbjct: 701 IAFDYRQQFKTDVVIDMICYRRHGHNEGDDPSYTQPILYRK 741 Score = 95.9 bits (228), Expect = 7e-19 Identities = 49/85 (57%), Positives = 63/85 (74%), Gaps = 1/85 (1%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTN-KNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKK 179 SGDVKYHLG + R +N + I ++V NPSHLEAVDPVV+G R +Q GD E ++ Sbjct: 557 SGDVKYHLGA--TGMRRTSNGREIVVSVSPNPSHLEAVDPVVEGIVRPKQDRLGDTERER 614 Query: 180 VMSILLHGDAAFAGQGVVFETMHLS 254 V+ +L+HGDAAFAGQGVV ET++LS Sbjct: 615 VIPVLIHGDAAFAGQGVVTETLNLS 639 Score = 47.6 bits (108), Expect = 3e-04 Identities = 19/47 (40%), Positives = 34/47 (72%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDVK 648 +NE D+P +TQP++Y+KI++ V Y +L+ EGV++ EEV+ ++ Sbjct: 725 HNEGDDPSYTQPILYRKIKEHPSVATLYGRRLVREGVLSVEEVQGMQ 771 >UniRef50_Q5PB66 Cluster: 2-oxoglutarate dehydrogenase E1 component; n=13; Rickettsiales|Rep: 2-oxoglutarate dehydrogenase E1 component - Anaplasma marginale (strain St. Maries) Length = 930 Score = 112 bits (269), Expect = 8e-24 Identities = 48/98 (48%), Positives = 69/98 (70%) Frame = +2 Query: 266 YTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCNVAA 445 Y+ G +H+V NNQ+GFT DP S +S YC+DVA++++AP+FHVNGD+PE+V+ V ++A Sbjct: 374 YSPGGIVHVVVNNQVGFTADPESSMTSFYCSDVAKMIDAPVFHVNGDDPESVLLVADLAM 433 Query: 446 EWRATFHKDVVIDIVSYRRNGTTKSTNRCSLSPSCTRR 559 E+R+ F KDVV+DIV YRR G + P +R Sbjct: 434 EYRSKFGKDVVVDIVCYRRFGHNEGDEPMFTQPLMYKR 471 Score = 69.3 bits (162), Expect = 7e-11 Identities = 37/84 (44%), Positives = 54/84 (64%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 182 SGDVKYHLG + ++ + + L++ N S LE+V+PVV G+ +A + D + + V Sbjct: 292 SGDVKYHLGYSTD--TKIGGETVHLSLAYNSSSLESVNPVVMGRVKA----KSDEKRQPV 345 Query: 183 MSILLHGDAAFAGQGVVFETMHLS 254 + IL+HG+AAF GQGVV E LS Sbjct: 346 LGILVHGNAAFIGQGVVSEGFTLS 369 Score = 58.8 bits (136), Expect = 1e-07 Identities = 27/43 (62%), Positives = 34/43 (79%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEV 636 +NE DEPMFTQPLMY++I K V YA++LI+EGVVT E+V Sbjct: 455 HNEGDEPMFTQPLMYKRIAAHKTVASLYAERLISEGVVTKEDV 497 >UniRef50_Q2S3D2 Cluster: 2-oxoglutarate dehydrogenase, E1 component; n=3; Bacteria|Rep: 2-oxoglutarate dehydrogenase, E1 component - Salinibacter ruber (strain DSM 13855) Length = 1243 Score = 111 bits (268), Expect = 1e-23 Identities = 49/84 (58%), Positives = 63/84 (75%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCN 436 L YTT GT+H+V NNQIGFTT P +RSS Y TD+AR + APIFHVNGD+PE + + Sbjct: 681 LRGYTTGGTVHLVINNQIGFTTPPGDARSSTYATDLARAIEAPIFHVNGDDPETCVRIAR 740 Query: 437 VAAEWRATFHKDVVIDIVSYRRNG 508 +A E+R F+KDVVID++ YR +G Sbjct: 741 LAFEYRQRFNKDVVIDMMCYRVHG 764 Score = 78.2 bits (184), Expect = 2e-13 Identities = 45/92 (48%), Positives = 60/92 (65%), Gaps = 8/92 (8%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKK- 179 SGDVKYHLG + + N+ I + + +NPSHLEAV+PVV+G +RA+Q D + Sbjct: 589 SGDVKYHLGAEGDVTSPDGNE-ISVTLASNPSHLEAVNPVVEGMSRAKQNLLRDEHPEAA 647 Query: 180 -------VMSILLHGDAAFAGQGVVFETMHLS 254 VM +L+HGDA FAGQGVV ET++LS Sbjct: 648 EDDYHDAVMPLLIHGDAGFAGQGVVAETLNLS 679 Score = 44.8 bits (101), Expect = 0.002 Identities = 18/48 (37%), Positives = 30/48 (62%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDVKD 651 +NE DEP FTQPL+Y+KI + + + Y + L+ G + +E + + D Sbjct: 765 HNEGDEPTFTQPLLYEKIEEKRSPRKLYTEMLLRRGEIEPDEAEQMLD 812 >UniRef50_Q7UM46 Cluster: Alpha-ketoglutarate dehydrogenase E1; n=4; Bacteria|Rep: Alpha-ketoglutarate dehydrogenase E1 - Rhodopirellula baltica Length = 969 Score = 111 bits (266), Expect = 2e-23 Identities = 46/85 (54%), Positives = 65/85 (76%) Frame = +2 Query: 254 DLPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVC 433 +L Y T GT+H+V NNQ+GFTT+P RS+ Y TD+A+++ PIFHVNG++PEAV V Sbjct: 407 ELKGYRTGGTLHVVINNQVGFTTEPDEGRSTTYATDIAKMLQIPIFHVNGEDPEAVAQVV 466 Query: 434 NVAAEWRATFHKDVVIDIVSYRRNG 508 ++A ++R FH+DVVID+ +YRR G Sbjct: 467 SLAMDFRKEFHRDVVIDLYAYRRWG 491 Score = 90.2 bits (214), Expect = 4e-17 Identities = 43/83 (51%), Positives = 59/83 (71%) Frame = +3 Query: 6 GDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKVM 185 GDV+YHLG Y + + +++C NPSHLE V+ V G+TR +Q RGD + + VM Sbjct: 325 GDVRYHLG-YSSDWKTASGDRLHISLCFNPSHLEYVNTVALGRTRCKQDNRGDVDRQDVM 383 Query: 186 SILLHGDAAFAGQGVVFETMHLS 254 +IL+HGDAAFAG+GVV ET++LS Sbjct: 384 TILIHGDAAFAGEGVVQETLNLS 406 Score = 41.5 bits (93), Expect = 0.017 Identities = 18/46 (39%), Positives = 29/46 (63%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDV 645 +NE DEP FTQP MY +I + V ++Y ++L+ G +T E ++ Sbjct: 492 HNEGDEPRFTQPQMYAEIDRRPGVRQQYLNRLLKLGKITEAEADEI 537 >UniRef50_A6GF68 Cluster: Alpha-ketoglutarate decarboxylase; n=1; Plesiocystis pacifica SIR-1|Rep: Alpha-ketoglutarate decarboxylase - Plesiocystis pacifica SIR-1 Length = 927 Score = 110 bits (265), Expect = 2e-23 Identities = 48/97 (49%), Positives = 62/97 (63%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCN 436 L Y G I +V NNQIGFTTDP +RS Y TDVA V+ P+FHVNGD+PEA +V Sbjct: 357 LEGYEAGGVIRVVINNQIGFTTDPTDARSGVYATDVAHVLGVPVFHVNGDDPEAAAYVAR 416 Query: 437 VAAEWRATFHKDVVIDIVSYRRNGTTKSTNRCSLSPS 547 +A WR FH+DV+ID+V YR+ G + + P+ Sbjct: 417 LAVAWRERFHRDVIIDLVCYRQFGHNEGDDPTFTQPT 453 Score = 84.6 bits (200), Expect = 2e-15 Identities = 40/84 (47%), Positives = 59/84 (70%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 182 +GDVKYHLG Y T+++I LA+ NPSHLEA+ PV+QG+ RA+Q + Sbjct: 273 AGDVKYHLG-YHRYHKTSTDRDIYLALAFNPSHLEAITPVIQGRVRAKQDANPERGHAAS 331 Query: 183 MSILLHGDAAFAGQGVVFETMHLS 254 +++ +HGDAAF+GQGVV ET++++ Sbjct: 332 LAVTMHGDAAFSGQGVVSETLNMA 355 Score = 42.3 bits (95), Expect = 0.010 Identities = 19/48 (39%), Positives = 26/48 (54%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDVKD 651 +NE D+P FTQP MY I+ V Y +L+ G +T KD+ D Sbjct: 441 HNEGDDPTFTQPTMYGLIKGRPSVRSLYQKRLVERGTITEAACKDIAD 488 >UniRef50_Q00UK1 Cluster: Predicted 2-oxoglutarate dehydrogenase, E1 subunit; n=3; cellular organisms|Rep: Predicted 2-oxoglutarate dehydrogenase, E1 subunit - Ostreococcus tauri Length = 1210 Score = 110 bits (265), Expect = 2e-23 Identities = 50/102 (49%), Positives = 70/102 (68%) Frame = +2 Query: 254 DLPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVC 433 DLP Y+T GT+H++ NNQIGFTT PR +RSS + +DVA+ API HVNGD+P+AV+ Sbjct: 400 DLPDYSTGGTVHVIVNNQIGFTTVPRRARSSPHPSDVAKAYGAPIIHVNGDDPDAVIRAM 459 Query: 434 NVAAEWRATFHKDVVIDIVSYRRNGTTKSTNRCSLSPSCTRR 559 +AA++RA F DVV++ V YRR G + + P ++R Sbjct: 460 RLAADYRAEFQSDVVVNYVCYRRFGHNELDDPSITLPLMSKR 501 Score = 61.7 bits (143), Expect = 1e-08 Identities = 36/90 (40%), Positives = 47/90 (52%), Gaps = 8/90 (8%) Frame = +3 Query: 6 GDVKYHLGTYIE---RLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYR-----G 161 GDV+YHLG + + + + + NPSHLE V+ VV G RA+QF R G Sbjct: 309 GDVRYHLGARARVDVEIEEGEKRPVTMTLVPNPSHLEMVNAVVSGVVRAKQFRRDPEAQG 368 Query: 162 DNEGKKVMSILLHGDAAFAGQGVVFETMHL 251 V+ +LLHGDA+F G G E M L Sbjct: 369 AGARAHVLPLLLHGDASFCGLGQTAEVMTL 398 Score = 44.4 bits (100), Expect = 0.002 Identities = 18/48 (37%), Positives = 34/48 (70%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDVKD 651 +NE+D+P T PLM ++I T V YA+ +AEG+++ +E++++K+ Sbjct: 485 HNELDDPSITLPLMSKRIDSTPRVAATYANVCVAEGMLSNDELRELKE 532 >UniRef50_P51056 Cluster: 2-oxoglutarate dehydrogenase E1 component; n=11; Proteobacteria|Rep: 2-oxoglutarate dehydrogenase E1 component - Coxiella burnetii Length = 934 Score = 110 bits (265), Expect = 2e-23 Identities = 47/83 (56%), Positives = 67/83 (80%), Gaps = 1/83 (1%) Frame = +2 Query: 263 AYTTHGTIHIVANNQIGFTT-DPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCNV 439 A+ G+IHI+ NNQ+GFTT +P +RSS YC+D+A++++AP+FHVNGD+PEAV+ V + Sbjct: 375 AHHVGGSIHIILNNQVGFTTSNPHDARSSMYCSDIAKMLDAPVFHVNGDDPEAVVAVTQL 434 Query: 440 AAEWRATFHKDVVIDIVSYRRNG 508 A ++R FHKDV ID+V YRR+G Sbjct: 435 ALDYRMAFHKDVFIDLVCYRRHG 457 Score = 70.1 bits (164), Expect = 4e-11 Identities = 34/84 (40%), Positives = 51/84 (60%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 182 SGDVKYH G R + I L++ NPSHLE + PV G RA Q + ++ Sbjct: 290 SGDVKYHRG--YSRDVKTDAGPIHLSLAFNPSHLEFICPVAMGSVRARQERQNGHKRDYA 347 Query: 183 MSILLHGDAAFAGQGVVFETMHLS 254 M++++HGDA+F+G+G+V E + +S Sbjct: 348 MTVMIHGDASFSGEGIVMEALSMS 371 Score = 39.9 bits (89), Expect = 0.052 Identities = 20/43 (46%), Positives = 27/43 (62%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEV 636 + EVD+PM TQP MY+ I++ YA LI + + TAEEV Sbjct: 458 HQEVDDPMPTQPAMYKVIQEHPTTRTLYAKNLIEKKLCTAEEV 500 >UniRef50_Q8YJE4 Cluster: 2-oxoglutarate dehydrogenase E1 component; n=97; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1 component - Brucella melitensis Length = 1004 Score = 110 bits (265), Expect = 2e-23 Identities = 50/84 (59%), Positives = 62/84 (73%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCN 436 L + GT+H + NNQIGFTT+P SRSS Y +DVA+++ APIFHVNGD+PEAV+ Sbjct: 431 LKGHRVAGTLHFIINNQIGFTTNPAFSRSSPYPSDVAKMIEAPIFHVNGDDPEAVVFAAK 490 Query: 437 VAAEWRATFHKDVVIDIVSYRRNG 508 VA E+R TFHK VVID+ YRR G Sbjct: 491 VATEFRMTFHKPVVIDMFCYRRFG 514 Score = 82.6 bits (195), Expect = 7e-15 Identities = 49/93 (52%), Positives = 59/93 (63%), Gaps = 9/93 (9%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFY-----RGD- 164 SGDVKYHLG +R + L++ ANPSHLE V+PVV GK RA+Q R D Sbjct: 339 SGDVKYHLGASSDR--EFDGNKVHLSLTANPSHLEIVNPVVMGKARAKQDLLVGRTRDDM 396 Query: 165 ---NEGKKVMSILLHGDAAFAGQGVVFETMHLS 254 +E KV+ +LLHGDAAFAGQGVV E + LS Sbjct: 397 VPLSERAKVLPLLLHGDAAFAGQGVVAECLGLS 429 Score = 55.6 bits (128), Expect = 1e-06 Identities = 24/47 (51%), Positives = 35/47 (74%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDVK 648 +NE DEP FTQPLMY+ IR K ++ Y ++LIAEG+VT +++ +K Sbjct: 515 HNEGDEPSFTQPLMYKAIRAHKTTVQLYGEKLIAEGLVTQDDIDRMK 561 >UniRef50_UPI00006CD2E0 Cluster: 2-oxoglutarate dehydrogenase, E1 component family protein; n=1; Tetrahymena thermophila SB210|Rep: 2-oxoglutarate dehydrogenase, E1 component family protein - Tetrahymena thermophila SB210 Length = 1054 Score = 110 bits (264), Expect = 3e-23 Identities = 52/85 (61%), Positives = 59/85 (69%) Frame = +2 Query: 254 DLPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVC 433 DL Y G IHIV NNQIGFTT P SR++ YCT VA V APIFHVN D PE V V Sbjct: 457 DLKDYNNGGIIHIVVNNQIGFTTYPGDSRTTLYCTAVAETVQAPIFHVNADEPELVDAVM 516 Query: 434 NVAAEWRATFHKDVVIDIVSYRRNG 508 +A ++R TFHKDVVIDI+ YR+ G Sbjct: 517 RLALDYRQTFHKDVVIDIIGYRKFG 541 Score = 91.9 bits (218), Expect = 1e-17 Identities = 44/83 (53%), Positives = 58/83 (69%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 182 SGDVKYHLGT ++ + +RL++ ANPSHLEAV+PVV GK R Q D G K Sbjct: 375 SGDVKYHLGTTKDKA--YGDHTVRLSIMANPSHLEAVNPVVYGKLRCVQDATQDTNGDKS 432 Query: 183 MSILLHGDAAFAGQGVVFETMHL 251 IL+HGDAAF+GQG+V+E++ + Sbjct: 433 FGILIHGDAAFSGQGIVYESIQM 455 Score = 46.0 bits (104), Expect = 8e-04 Identities = 21/45 (46%), Positives = 30/45 (66%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKD 642 +NE+D+P +TQP M + I+ KPV KY D+L E V+T E K+ Sbjct: 542 HNELDQPAYTQPQMQKIIQSMKPVYLKYMDKLYKENVLTPEIEKE 586 >UniRef50_Q12AA2 Cluster: 2-oxoglutarate dehydrogenase, E1 component; n=12; root|Rep: 2-oxoglutarate dehydrogenase, E1 component - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 963 Score = 110 bits (264), Expect = 3e-23 Identities = 49/82 (59%), Positives = 63/82 (76%), Gaps = 1/82 (1%) Frame = +2 Query: 266 YTTHGTIHIVANNQIGFTT-DPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCNVA 442 Y T GT+HIV NNQIGFTT DPR SRS+ YCTDV +++ AP+ HVNGD+PEAV+ +A Sbjct: 393 YFTGGTVHIVINNQIGFTTSDPRDSRSTLYCTDVVKMIEAPVLHVNGDDPEAVVLATQLA 452 Query: 443 AEWRATFHKDVVIDIVSYRRNG 508 E+R F KDVV+DI+ +R+ G Sbjct: 453 LEFRMEFQKDVVVDIICFRKLG 474 Score = 83.0 bits (196), Expect = 6e-15 Identities = 42/84 (50%), Positives = 55/84 (65%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 182 SGDVKYH G + + L++ NPSHLE V+PVV+G RA R D +G +V Sbjct: 307 SGDVKYHQGFSSDVTT--PGGPVHLSLAFNPSHLEIVNPVVEGSVRARMDRRADPKGLQV 364 Query: 183 MSILLHGDAAFAGQGVVFETMHLS 254 + +L+HGDAAFAGQGVV ET+ L+ Sbjct: 365 LPVLVHGDAAFAGQGVVMETLALA 388 Score = 39.5 bits (88), Expect = 0.068 Identities = 18/37 (48%), Positives = 24/37 (64%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGV 618 +NE D P TQPLMY+KI + YAD+L A+G+ Sbjct: 475 HNEQDTPALTQPLMYKKIAQHPGTRRLYADKLSAQGM 511 >UniRef50_A7BE99 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 1304 Score = 109 bits (263), Expect = 4e-23 Identities = 49/96 (51%), Positives = 63/96 (65%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCN 436 L Y T GTIHI+ NNQIGFTT P RS+ Y TD+A+ + PI HVN D+PEAV+ + Sbjct: 723 LEGYKTGGTIHIIVNNQIGFTTGPTQGRSTGYATDLAKGLQVPILHVNADDPEAVIRCAH 782 Query: 437 VAAEWRATFHKDVVIDIVSYRRNGTTKSTNRCSLSP 544 +A E+R FHKDV+ID+V YRR G + + P Sbjct: 783 LAFEYRNAFHKDVIIDMVCYRRRGHNEGDDPSMTQP 818 Score = 81.0 bits (191), Expect = 2e-14 Identities = 45/85 (52%), Positives = 60/85 (70%), Gaps = 1/85 (1%) Frame = +3 Query: 3 SGDVKYHLGTY-IERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKK 179 SGDVKYHLGT+ + L+ + +A ANPSHLEA D V++G RA+Q + GD + Sbjct: 640 SGDVKYHLGTWGVYSLDDGLATKVYMA--ANPSHLEAADGVLEGIVRAKQEHLGDPD-LP 696 Query: 180 VMSILLHGDAAFAGQGVVFETMHLS 254 ++ IL+HGDAAF GQGVV ET++LS Sbjct: 697 IIPILIHGDAAFIGQGVVQETLNLS 721 Score = 34.3 bits (75), Expect = 2.6 Identities = 15/48 (31%), Positives = 25/48 (52%) Frame = +1 Query: 496 QEKRNNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVK 639 + + +NE D+P TQP+MY I + Y L+ G +T +E + Sbjct: 803 RRRGHNEGDDPSMTQPVMYSLIDRIPSTRAVYIRGLVGRGQLTEDEAR 850 >UniRef50_A5EW58 Cluster: 2-oxoglutarate dehydrogenase, E1 component; n=1; Dichelobacter nodosus VCS1703A|Rep: 2-oxoglutarate dehydrogenase, E1 component - Dichelobacter nodosus (strain VCS1703A) Length = 917 Score = 109 bits (263), Expect = 4e-23 Identities = 49/96 (51%), Positives = 63/96 (65%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCN 436 L Y G +HIV NNQIGFTT +RSS YCTD+A+ + AP+ HVNGD+PEAV V Sbjct: 368 LRGYFCGGAVHIVVNNQIGFTTTKTDARSSLYCTDIAKSIQAPVIHVNGDDPEAVFFVAQ 427 Query: 437 VAAEWRATFHKDVVIDIVSYRRNGTTKSTNRCSLSP 544 +AA +R FHKD+ ID+V YRR G ++ +P Sbjct: 428 LAAAYRLRFHKDIFIDLVCYRRLGHNEADEPAITNP 463 Score = 64.5 bits (150), Expect = 2e-09 Identities = 38/91 (41%), Positives = 57/91 (62%), Gaps = 7/91 (7%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGK-- 176 +GDVKYHLG + R+ + ++++L++ NPSHLE V+ V G RA+ + + EG Sbjct: 278 NGDVKYHLG-FTARV-QYQAQSVQLSLMYNPSHLEFVNAVALGFARAQLEHCSEKEGATI 335 Query: 177 -----KVMSILLHGDAAFAGQGVVFETMHLS 254 KV+ IL+HGDAA +GQG+ E + LS Sbjct: 336 MAAADKVVPILIHGDAALSGQGINQEVLQLS 366 Score = 37.5 bits (83), Expect = 0.28 Identities = 17/38 (44%), Positives = 23/38 (60%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVV 621 +NE DEP T P MY I++ + YA+QLIA G + Sbjct: 452 HNEADEPAITNPKMYDLIQRHETPARIYANQLIAAGAL 489 >UniRef50_Q9RXM3 Cluster: 2-oxoglutarate dehydrogenase, E1 component; n=15; Bacteria|Rep: 2-oxoglutarate dehydrogenase, E1 component - Deinococcus radiodurans Length = 956 Score = 109 bits (262), Expect = 6e-23 Identities = 51/85 (60%), Positives = 63/85 (74%), Gaps = 1/85 (1%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFT-TDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVC 433 L +TT G I IV NNQIGFT +DPR SRSS YCTDVA++ NAP+ HVNGD+PEAV Sbjct: 372 LRGFTTGGAIRIVINNQIGFTISDPRDSRSSRYCTDVAKIANAPVMHVNGDDPEAVAFCG 431 Query: 434 NVAAEWRATFHKDVVIDIVSYRRNG 508 ++A +R F KDV ID++ +RRNG Sbjct: 432 DLALAYRQEFGKDVFIDLICFRRNG 456 Score = 87.4 bits (207), Expect = 3e-16 Identities = 45/84 (53%), Positives = 56/84 (66%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 182 +GDVKYH+G Y + R + LA+ NPSHLE V PVV G RA Q RGD E K+V Sbjct: 289 AGDVKYHMG-YSSDV-RTPGGPMHLAMAFNPSHLEIVSPVVHGSVRARQDRRGDTERKQV 346 Query: 183 MSILLHGDAAFAGQGVVFETMHLS 254 + I +HGDAA +GQGVV ET++ S Sbjct: 347 LPITVHGDAAVSGQGVVMETLNFS 370 Score = 38.3 bits (85), Expect = 0.16 Identities = 19/42 (45%), Positives = 26/42 (61%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEE 633 +NE DEP TQP+MY++I + YA QL +GV+ A E Sbjct: 457 HNEGDEPRMTQPVMYREIDQHPGTRALYAAQLEKDGVLAAGE 498 >UniRef50_P20707 Cluster: 2-oxoglutarate dehydrogenase E1 component; n=149; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1 component - Azotobacter vinelandii Length = 943 Score = 109 bits (262), Expect = 6e-23 Identities = 49/94 (52%), Positives = 66/94 (70%), Gaps = 1/94 (1%) Frame = +2 Query: 266 YTTHGTIHIVANNQIGFTT-DPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCNVA 442 Y T GTIHIV NNQ+GFTT +P +RS+ YCTD A+++ AP+ HVNGD+PEAV+ V +A Sbjct: 384 YKTGGTIHIVVNNQVGFTTSNPVDTRSTEYCTDPAKMIQAPVLHVNGDDPEAVLFVTQLA 443 Query: 443 AEWRATFHKDVVIDIVSYRRNGTTKSTNRCSLSP 544 ++R F +DVVID+V YRR G ++ P Sbjct: 444 VDYRMQFKRDVVIDLVCYRRRGHNEADEPSGTQP 477 Score = 85.8 bits (203), Expect = 8e-16 Identities = 44/84 (52%), Positives = 54/84 (64%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 182 SGDVKYH G + + + LA+ NPSHLE V PVV+G RA Q R D G+KV Sbjct: 298 SGDVKYHQGFSSNVMT--SGGEVHLAMAFNPSHLEIVSPVVEGSVRARQDRRVDATGEKV 355 Query: 183 MSILLHGDAAFAGQGVVFETMHLS 254 + I +HGD+AFAGQGVV ET +S Sbjct: 356 VPISIHGDSAFAGQGVVMETFQMS 379 Score = 53.6 bits (123), Expect = 4e-06 Identities = 25/48 (52%), Positives = 32/48 (66%) Frame = +1 Query: 496 QEKRNNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVK 639 + + +NE DEP TQPLMYQKI K E YAD L+ EG ++ EEV+ Sbjct: 462 RRRGHNEADEPSGTQPLMYQKIAKQPTTRELYADALVKEGSLSQEEVQ 509 >UniRef50_A5K5P2 Cluster: 2-oxoglutarate dehydrogenase E1 component, mitochondrial, putative; n=9; Plasmodium|Rep: 2-oxoglutarate dehydrogenase E1 component, mitochondrial, putative - Plasmodium vivax Length = 1059 Score = 108 bits (260), Expect = 1e-22 Identities = 49/84 (58%), Positives = 60/84 (71%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCN 436 LP+Y GTIHIV NNQIGFTT P +RS YCTD+A+ ++ PI HVN D+PEAV +V Sbjct: 432 LPSYNVGGTIHIVVNNQIGFTTYPVDARSGKYCTDIAKCIDIPIIHVNADDPEAVTYVFE 491 Query: 437 VAAEWRATFHKDVVIDIVSYRRNG 508 +A + R FH D +IDIV YRR G Sbjct: 492 LALDIRNKFHIDTIIDIVGYRRFG 515 Score = 99.1 bits (236), Expect = 8e-20 Identities = 40/84 (47%), Positives = 61/84 (72%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 182 +GDVKYHLG I+ + +N+ I + + N SHLE+VDP++ G+ RA+Q+Y D E +KV Sbjct: 347 TGDVKYHLGVEIDHFDEESNRYIHMGIVDNSSHLESVDPILMGQARAQQYYCNDKEKEKV 406 Query: 183 MSILLHGDAAFAGQGVVFETMHLS 254 + I +HGDA+ AGQG+ +ET+ +S Sbjct: 407 LPITIHGDASIAGQGIAYETLQMS 430 Score = 47.2 bits (107), Expect = 3e-04 Identities = 21/47 (44%), Positives = 32/47 (68%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDVK 648 +NE+D P FT PL+Y I + + VL+ Y+ +LI EGV++ EE + K Sbjct: 516 HNELDMPKFTNPLLYDIITRHESVLDLYSKKLIREGVISLEEFEQNK 562 >UniRef50_Q9PD29 Cluster: Oxoglutarate dehydrogenase; n=17; Bacteria|Rep: Oxoglutarate dehydrogenase - Xylella fastidiosa Length = 967 Score = 108 bits (259), Expect = 1e-22 Identities = 48/94 (51%), Positives = 67/94 (71%), Gaps = 1/94 (1%) Frame = +2 Query: 266 YTTHGTIHIVANNQIGFTTDPRH-SRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCNVA 442 + GT+H++ NNQIGFTT R +RS+ YCTDVA+++ AP+FHVNGD+P+AV+ V +A Sbjct: 405 FAVGGTLHVIINNQIGFTTSARDDARSTPYCTDVAKMIGAPVFHVNGDDPDAVVFVAQLA 464 Query: 443 AEWRATFHKDVVIDIVSYRRNGTTKSTNRCSLSP 544 E+R F KDVVID+V YRR G ++ + P Sbjct: 465 YEFRQQFKKDVVIDLVCYRRWGHNEADEPAATQP 498 Score = 90.6 bits (215), Expect = 3e-17 Identities = 45/84 (53%), Positives = 56/84 (66%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 182 +GDVKYH+G + + K + LA+ NPSHLE VDPVV G R+ Q GD E K V Sbjct: 318 TGDVKYHMG-FSADIAVGDGKQVHLALAFNPSHLEIVDPVVAGSVRSRQERFGDTERKTV 376 Query: 183 MSILLHGDAAFAGQGVVFETMHLS 254 + IL+HGDAAFAGQGVV E + +S Sbjct: 377 LPILIHGDAAFAGQGVVMELLQMS 400 Score = 55.2 bits (127), Expect = 1e-06 Identities = 27/48 (56%), Positives = 32/48 (66%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDVKD 651 +NE DEP TQP+MYQ IRK K E YA +L AEGV+ A E K + D Sbjct: 487 HNEADEPAATQPVMYQTIRKHKTTRELYATKLEAEGVIAAGEAKAMVD 534 >UniRef50_A3ZXH0 Cluster: Alpha-ketoglutarate dehydrogenase E1; n=1; Blastopirellula marina DSM 3645|Rep: Alpha-ketoglutarate dehydrogenase E1 - Blastopirellula marina DSM 3645 Length = 929 Score = 107 bits (257), Expect = 2e-22 Identities = 47/84 (55%), Positives = 62/84 (73%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCN 436 L Y T GT+H++ NNQ+GFTT P SRS+ Y TDVAR++ +PIFHVNG+NP AV V + Sbjct: 369 LHGYRTGGTLHVIVNNQLGFTTQPHDSRSTIYATDVARMLQSPIFHVNGENPAAVSQVVS 428 Query: 437 VAAEWRATFHKDVVIDIVSYRRNG 508 +A E+R T +DVVID+ +RR G Sbjct: 429 LALEFRRTHQRDVVIDMYCFRRFG 452 Score = 90.6 bits (215), Expect = 3e-17 Identities = 43/83 (51%), Positives = 59/83 (71%) Frame = +3 Query: 6 GDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKVM 185 GDVKYH+G + + + K + +++C NPSHLE VDPV G+ RA+Q RGD E + Sbjct: 286 GDVKYHMGASGDYV-AASGKKVHVSLCFNPSHLEYVDPVALGRMRAKQDRRGDTERQMGA 344 Query: 186 SILLHGDAAFAGQGVVFETMHLS 254 +L+HGDAAFAG+GVV ET++LS Sbjct: 345 VVLIHGDAAFAGEGVVQETLNLS 367 Score = 43.6 bits (98), Expect = 0.004 Identities = 17/46 (36%), Positives = 28/46 (60%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDV 645 +NE DEP FTQPL+YQ I + + +++ D L+ G +E ++ Sbjct: 453 HNETDEPSFTQPLLYQAIEHHRSIRDRFLDNLVELGQFEVQEADEM 498 >UniRef50_P45303 Cluster: 2-oxoglutarate dehydrogenase E1 component; n=70; Proteobacteria|Rep: 2-oxoglutarate dehydrogenase E1 component - Haemophilus influenzae Length = 935 Score = 107 bits (256), Expect = 3e-22 Identities = 47/94 (50%), Positives = 66/94 (70%), Gaps = 1/94 (1%) Frame = +2 Query: 266 YTTHGTIHIVANNQIGFTT-DPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCNVA 442 Y+ GTI IV NNQIGFTT +P +RS+ YCTD+A+++ API HVNGD+PEAV +A Sbjct: 381 YSVGGTIRIVINNQIGFTTSNPNDTRSTEYCTDIAKMIQAPIIHVNGDDPEAVAFAARMA 440 Query: 443 AEWRATFHKDVVIDIVSYRRNGTTKSTNRCSLSP 544 E+R F +D+ ID++SYRR+G ++ + P Sbjct: 441 VEYRNLFKRDIFIDLISYRRHGHNEADEPLATQP 474 Score = 80.6 bits (190), Expect = 3e-14 Identities = 41/84 (48%), Positives = 54/84 (64%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 182 +GDVKYH G + V +K + L + NPSHLE V PVV G R+ Q D E KV Sbjct: 295 TGDVKYHQGFSSDFA--VDDKRVHLTLAFNPSHLEIVSPVVIGSVRSRQTRMNDTEHSKV 352 Query: 183 MSILLHGDAAFAGQGVVFETMHLS 254 ++I +HGD+A AGQGVV ET+++S Sbjct: 353 LAITVHGDSAVAGQGVVQETLNMS 376 Score = 52.0 bits (119), Expect = 1e-05 Identities = 22/46 (47%), Positives = 34/46 (73%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDV 645 +NE DEP+ TQP+MY I+K + YAD+L++EGV+T E+V ++ Sbjct: 463 HNEADEPLATQPMMYSIIKKHPTPRKVYADRLVSEGVMTEEQVTEM 508 >UniRef50_Q23MM6 Cluster: 2-oxoglutarate dehydrogenase, E1 component family protein; n=1; Tetrahymena thermophila SB210|Rep: 2-oxoglutarate dehydrogenase, E1 component family protein - Tetrahymena thermophila SB210 Length = 1004 Score = 106 bits (255), Expect = 4e-22 Identities = 42/84 (50%), Positives = 59/84 (70%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCN 436 +P ++ GTIH++ NNQIGFTT+P R YC+D+A+ + PI HVN D+PEA+ VC Sbjct: 392 VPKFSVGGTIHMIVNNQIGFTTNPIDGRGGFYCSDIAKAFDTPIIHVNSDDPEAIHRVCK 451 Query: 437 VAAEWRATFHKDVVIDIVSYRRNG 508 A E+R F KD++ID++ YRR G Sbjct: 452 FAVEYRQRFQKDILIDVIGYRRYG 475 Score = 60.1 bits (139), Expect = 5e-08 Identities = 31/61 (50%), Positives = 42/61 (68%) Frame = +3 Query: 69 IRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVVFETMH 248 I +++ NPSHLEAV+PV GK RA+ + E V++I LHGDAAF+ QGVV+E+ Sbjct: 332 INVSLLHNPSHLEAVNPVSMGKARAKMDEKTKTE---VLNIQLHGDAAFSAQGVVYESFA 388 Query: 249 L 251 L Sbjct: 389 L 389 Score = 37.1 bits (82), Expect = 0.36 Identities = 16/41 (39%), Positives = 23/41 (56%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAE 630 +NE+DEP FTQP MY I+ T+ + D + E + E Sbjct: 476 HNELDEPEFTQPHMYNHIKNTQKTCPQLYDSKLIESKIVKE 516 >UniRef50_A0DG23 Cluster: Chromosome undetermined scaffold_5, whole genome shotgun sequence; n=4; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_5, whole genome shotgun sequence - Paramecium tetraurelia Length = 1002 Score = 106 bits (255), Expect = 4e-22 Identities = 46/85 (54%), Positives = 58/85 (68%) Frame = +2 Query: 254 DLPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVC 433 DL Y + G IH+V+NNQIGFTT P+ SRS YCTD+A + AP+ HVN D PE V V Sbjct: 410 DLEGYKSGGIIHVVSNNQIGFTTVPKDSRSGLYCTDIAHAIQAPVIHVNADEPELVDKVF 469 Query: 434 NVAAEWRATFHKDVVIDIVSYRRNG 508 VA ++R F +D+ ID+V YRR G Sbjct: 470 QVATQYRTKFKRDIFIDLVGYRRYG 494 Score = 92.7 bits (220), Expect = 7e-18 Identities = 44/84 (52%), Positives = 57/84 (67%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 182 SGDVKYHLG+ + + + K +RL + NPSHLE VDP V GK RA Q Y D G K Sbjct: 328 SGDVKYHLGS-VHNV-KFGEKKLRLEMLPNPSHLETVDPCVYGKVRAIQDYHKDRNGDKA 385 Query: 183 MSILLHGDAAFAGQGVVFETMHLS 254 +L+HGDAA AGQG+VFE++ ++ Sbjct: 386 FGVLIHGDAAVAGQGIVFESLQMA 409 Score = 60.1 bits (139), Expect = 5e-08 Identities = 25/43 (58%), Positives = 34/43 (79%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEV 636 +NE D+P FTQP+MY KI KT PV K++++LIA+G+VT EV Sbjct: 495 HNEQDQPKFTQPIMYDKIEKTPPVFVKFSEKLIAQGIVTKAEV 537 >UniRef50_Q6BGE2 Cluster: 2-oxoglutarate dehydrogenase, putative; n=4; Paramecium tetraurelia|Rep: 2-oxoglutarate dehydrogenase, putative - Paramecium tetraurelia Length = 964 Score = 105 bits (252), Expect = 9e-22 Identities = 44/85 (51%), Positives = 58/85 (68%) Frame = +2 Query: 254 DLPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVC 433 +L Y+ G IH+V NNQIGFTT P SRS YCTDVA+ ++ PI HVN D+P+ V + Sbjct: 374 NLTGYSNEGVIHVVVNNQIGFTTTPIDSRSGLYCTDVAKAIDVPIIHVNADDPDLVEEIF 433 Query: 434 NVAAEWRATFHKDVVIDIVSYRRNG 508 +A +R F KD+VID++ YRR G Sbjct: 434 KIAVRFRQQFKKDIVIDLIGYRRYG 458 Score = 83.4 bits (197), Expect = 4e-15 Identities = 43/82 (52%), Positives = 57/82 (69%) Frame = +3 Query: 6 GDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKVM 185 GDVKYHLG ++ +IR+ + NPSHLEAV+PVVQGKTRA Q G+ + + Sbjct: 294 GDVKYHLGVTRDQ-QFPDGHHIRMTMLPNPSHLEAVNPVVQGKTRALQDICGNKQ--NCL 350 Query: 186 SILLHGDAAFAGQGVVFETMHL 251 I++HGDAA AGQGVV+E++ L Sbjct: 351 GIIIHGDAAMAGQGVVYESLQL 372 Score = 47.6 bits (108), Expect = 3e-04 Identities = 21/39 (53%), Positives = 26/39 (66%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVT 624 +NE D+P FTQP MY+ I K KPV + Y QL GV+T Sbjct: 459 HNEQDQPAFTQPQMYEIINKQKPVFQLYDQQLRKNGVIT 497 >UniRef50_Q7WRM3 Cluster: 2-oxoglutarate dehydrogenase E1 component; n=17; Staphylococcus|Rep: 2-oxoglutarate dehydrogenase E1 component - Staphylococcus aureus Length = 932 Score = 105 bits (252), Expect = 9e-22 Identities = 46/85 (54%), Positives = 63/85 (74%) Frame = +2 Query: 254 DLPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVC 433 +L Y+T G++HI+ NN+IGFTT+P +RS+ Y TDVA+ + PIFHVN D+ EA + Sbjct: 373 NLKGYSTGGSLHIITNNRIGFTTEPIDARSTTYSTDVAKGYDVPIFHVNADDVEATIEAI 432 Query: 434 NVAAEWRATFHKDVVIDIVSYRRNG 508 ++A E+R FHKDVVID+V YRR G Sbjct: 433 DIAMEFRKEFHKDVVIDLVGYRRFG 457 Score = 73.3 bits (172), Expect = 5e-12 Identities = 43/88 (48%), Positives = 56/88 (63%), Gaps = 5/88 (5%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQ--FYRGD---N 167 +GDVKYHLG + T + R+A+ NPSHLE V PVV+G+TRA Q R Sbjct: 286 TGDVKYHLGGIKTTDSYGTMQ--RIALANNPSHLEIVAPVVEGRTRAAQDDTQRAGAPTT 343 Query: 168 EGKKVMSILLHGDAAFAGQGVVFETMHL 251 + K M I++HGDAA+ GQG+ FETM+L Sbjct: 344 DHHKAMPIIIHGDAAYPGQGINFETMNL 371 Score = 41.9 bits (94), Expect = 0.013 Identities = 18/43 (41%), Positives = 28/43 (65%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEV 636 +NE+DEP T P+ YQ IRK V + +L+ EGV++ +E+ Sbjct: 458 HNEMDEPSITNPVPYQNIRKHDSVEYVFGKKLVNEGVISEDEM 500 >UniRef50_Q8F6S7 Cluster: 2-oxoglutarate dehydrogenase E1 component; n=4; Leptospira|Rep: 2-oxoglutarate dehydrogenase E1 component - Leptospira interrogans Length = 920 Score = 105 bits (252), Expect = 9e-22 Identities = 50/98 (51%), Positives = 62/98 (63%) Frame = +2 Query: 251 VDLPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHV 430 ++L YTT GT HIV NNQIGFTT P SRS+ Y TD+A+ PI HVNGD+PEAV V Sbjct: 359 MNLEGYTTGGTFHIVVNNQIGFTTLPDESRSTLYATDLAKGFQIPIIHVNGDDPEAVYRV 418 Query: 431 CNVAAEWRATFHKDVVIDIVSYRRNGTTKSTNRCSLSP 544 + E+R F KD +ID+V YRR G ++ P Sbjct: 419 VKLGMEYRQKFKKDFIIDLVCYRRLGHNETDEPAFTQP 456 Score = 94.3 bits (224), Expect = 2e-18 Identities = 46/81 (56%), Positives = 56/81 (69%) Frame = +3 Query: 9 DVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKVMS 188 DVKYHLG R+ + K ++L++ NPSHLE VDPVV G RA Q GD + K M Sbjct: 279 DVKYHLGYSNSRMT-TSGKEVKLSLAFNPSHLECVDPVVTGSVRARQTLIGDKDRSKYMP 337 Query: 189 ILLHGDAAFAGQGVVFETMHL 251 IL+HGDAAFAGQGVV ET++L Sbjct: 338 ILIHGDAAFAGQGVVAETLNL 358 Score = 46.0 bits (104), Expect = 8e-04 Identities = 19/48 (39%), Positives = 30/48 (62%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDVKD 651 +NE DEP FTQP MY I+ P ++ Y +L+ EG + E++ +K+ Sbjct: 445 HNETDEPAFTQPKMYAIIKNHPPTVKLYEKRLVEEGDIPQEDIDFIKN 492 >UniRef50_Q1R3M6 Cluster: 2-oxoglutarate dehydrogenase E1 component; n=5; Enterobacteriaceae|Rep: 2-oxoglutarate dehydrogenase E1 component - Escherichia coli (strain UTI89 / UPEC) Length = 939 Score = 105 bits (251), Expect = 1e-21 Identities = 47/86 (54%), Positives = 63/86 (73%), Gaps = 1/86 (1%) Frame = +2 Query: 266 YTTHGTIHIVANNQIGFTTDP-RHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCNVA 442 Y T GT+H+V NNQIGFTT + RSS YCTD+A++V API HVNGD+ +AV V +A Sbjct: 379 YGTGGTLHLVINNQIGFTTSRLQDMRSSRYCTDIAKMVAAPIIHVNGDDVDAVCQVMELA 438 Query: 443 AEWRATFHKDVVIDIVSYRRNGTTKS 520 EWR TF +D++IDI +R++G +S Sbjct: 439 CEWRDTFRRDIIIDICCFRKHGHNES 464 Score = 76.6 bits (180), Expect = 5e-13 Identities = 40/84 (47%), Positives = 54/84 (64%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 182 SGDVKYH+G Y L ++ +A+ NPSHLE V+PVV G+ RA Q RG++ KV Sbjct: 293 SGDVKYHMG-YSSNLETPAG-SLHVALAYNPSHLEIVNPVVLGQVRARQERRGEDGQAKV 350 Query: 183 MSILLHGDAAFAGQGVVFETMHLS 254 + +L+HGD+A G GV T +LS Sbjct: 351 VGVLIHGDSALGGLGVNQTTFNLS 374 Score = 37.1 bits (82), Expect = 0.36 Identities = 16/39 (41%), Positives = 22/39 (56%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVT 624 +NE DEP TQP MYQ + L +Y + L G++T Sbjct: 461 HNESDEPRLTQPQMYQAVDAHPGTLARYGESLARRGLLT 499 >UniRef50_Q5FSJ1 Cluster: 2-Oxoglutarate dehydrogenase E1 component; n=1; Gluconobacter oxydans|Rep: 2-Oxoglutarate dehydrogenase E1 component - Gluconobacter oxydans (Gluconobacter suboxydans) Length = 885 Score = 104 bits (249), Expect = 2e-21 Identities = 46/97 (47%), Positives = 62/97 (63%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCN 436 L Y T GT+H++ NNQIGFTT + S + TD+A+ V API HVNGD+PEAV Sbjct: 323 LEGYRTGGTVHVIINNQIGFTTVQSDAHSGLHNTDIAKSVQAPILHVNGDDPEAVSRCAF 382 Query: 437 VAAEWRATFHKDVVIDIVSYRRNGTTKSTNRCSLSPS 547 +A EWR TF D+V+D+V YRR+G ++ P+ Sbjct: 383 LAHEWRRTFQSDIVLDVVCYRRHGHNEADEPAFTQPA 419 Score = 93.9 bits (223), Expect = 3e-18 Identities = 47/84 (55%), Positives = 59/84 (70%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 182 SGDVKYHLGT + +R+++ NPSHLEAVDPVV G+ RA+Q D E + Sbjct: 240 SGDVKYHLGTATTLEH--AGHTVRISLLPNPSHLEAVDPVVLGRVRADQDREKDRERQHH 297 Query: 183 MSILLHGDAAFAGQGVVFETMHLS 254 + IL+HGDAAFAGQGVV+ET+ LS Sbjct: 298 LGILVHGDAAFAGQGVVYETLSLS 321 Score = 45.2 bits (102), Expect = 0.001 Identities = 21/46 (45%), Positives = 27/46 (58%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDV 645 +NE DEP FTQP M I+ YAD LI GV+T EV+++ Sbjct: 407 HNEADEPAFTQPAMVHAIQSRATTRSLYADHLIRTGVMTEAEVEEM 452 >UniRef50_Q057P3 Cluster: 2-oxoglutarate dehydrogenase E1 component; n=1; Buchnera aphidicola str. Cc (Cinara cedri)|Rep: 2-oxoglutarate dehydrogenase E1 component - Buchnera aphidicola subsp. Cinara cedri Length = 933 Score = 104 bits (249), Expect = 2e-21 Identities = 45/85 (52%), Positives = 64/85 (75%), Gaps = 1/85 (1%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPR-HSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVC 433 +PAY G+IHIV NN+I FTT + + R+S YCTD+A+++++P+FHVN D PE+V+ V Sbjct: 370 VPAYNVFGSIHIVINNKIAFTTSKKKYLRTSKYCTDIAKMIDSPVFHVNADKPESVISVI 429 Query: 434 NVAAEWRATFHKDVVIDIVSYRRNG 508 N+A ++R F KDV ID+V YRR G Sbjct: 430 NIALKFRYKFKKDVFIDLVGYRRLG 454 Score = 65.7 bits (153), Expect = 9e-10 Identities = 33/84 (39%), Positives = 52/84 (61%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 182 +GDVKYH+G +++ V N+ + + + NPSHLE + PVV G + F Sbjct: 289 TGDVKYHIG--LKKKIFVNNQEVEINLLNNPSHLEIITPVVIGCCKF--FIENKKTIISP 344 Query: 183 MSILLHGDAAFAGQGVVFETMHLS 254 + +++HGDAAF GQGV+ ET+++S Sbjct: 345 LPVIIHGDAAFTGQGVIQETLNMS 368 Score = 39.1 bits (87), Expect = 0.090 Identities = 15/32 (46%), Positives = 23/32 (71%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQL 603 +NEVD+P TQP+MY I+K KP+ Y+ ++ Sbjct: 455 HNEVDDPKITQPIMYSLIKKHKPICILYSKKI 486 >UniRef50_Q8NRC3 Cluster: 2-oxoglutarate dehydrogenase E1 component; n=45; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1 component - Corynebacterium glutamicum (Brevibacterium flavum) Length = 1257 Score = 103 bits (248), Expect = 3e-21 Identities = 50/96 (52%), Positives = 60/96 (62%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCN 436 L Y GTIHIV NNQIGFTT P SRS Y TD A+ P+FHVNGD+PEAV+ V Sbjct: 699 LRGYDVGGTIHIVVNNQIGFTTTPDSSRSMHYATDYAKAFGCPVFHVNGDDPEAVVWVGQ 758 Query: 437 VAAEWRATFHKDVVIDIVSYRRNGTTKSTNRCSLSP 544 +A E+R F KDV ID+V YR G ++ + P Sbjct: 759 LATEYRRRFGKDVFIDLVCYRLRGHNEADDPSMTQP 794 Score = 91.1 bits (216), Expect = 2e-17 Identities = 45/85 (52%), Positives = 63/85 (74%), Gaps = 1/85 (1%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDN-EGKK 179 SGDVKYHLG+ + L + I++++ ANPSHLEAV+PV++G RA+Q Y +GK Sbjct: 613 SGDVKYHLGSEGQHLQMFGDGEIKVSLTANPSHLEAVNPVMEGIVRAKQDYLDKGVDGKT 672 Query: 180 VMSILLHGDAAFAGQGVVFETMHLS 254 V+ +LLHGDAAFAG G+V ET++L+ Sbjct: 673 VVPLLLHGDAAFAGLGIVPETINLA 697 Score = 37.5 bits (83), Expect = 0.28 Identities = 16/46 (34%), Positives = 27/46 (58%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDV 645 +NE D+P TQP MY+ I + V +Y + L+ G ++ E+ + V Sbjct: 783 HNEADDPSMTQPKMYELITGRETVRAQYTEDLLGRGDLSNEDAEAV 828 >UniRef50_Q2GDI7 Cluster: 2-oxoglutarate dehydrogenase, E1 component; n=1; Neorickettsia sennetsu str. Miyayama|Rep: 2-oxoglutarate dehydrogenase, E1 component - Neorickettsia sennetsu (strain Miyayama) Length = 905 Score = 103 bits (247), Expect = 4e-21 Identities = 46/85 (54%), Positives = 61/85 (71%) Frame = +2 Query: 254 DLPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVC 433 +LP Y + G IHI+ NNQIGFTT P+ R Y + + + PIFHVNGD+PEAV +V Sbjct: 352 ELPNYESGGVIHIILNNQIGFTTSPQDVRKQRYPSFIGESFDIPIFHVNGDDPEAVFYVT 411 Query: 434 NVAAEWRATFHKDVVIDIVSYRRNG 508 +AAE+R TF+K ++DIVSYRR+G Sbjct: 412 LLAAEFRNTFNKSAIVDIVSYRRHG 436 Score = 80.2 bits (189), Expect = 4e-14 Identities = 42/82 (51%), Positives = 53/82 (64%) Frame = +3 Query: 6 GDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKVM 185 GDVKYH G ER ++ K I + NPSHL++VDPV+ G RA + + G V Sbjct: 274 GDVKYHYGFSCERKTFLSEKTIFARLLHNPSHLDSVDPVLVGAARAAK-----DSGAVVF 328 Query: 186 SILLHGDAAFAGQGVVFETMHL 251 +LLHGDAAF+GQGVV+ETM L Sbjct: 329 PVLLHGDAAFSGQGVVYETMLL 350 Score = 46.4 bits (105), Expect = 6e-04 Identities = 19/42 (45%), Positives = 30/42 (71%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEE 633 +NE+DEP FTQP MY I + K ++ Y ++LI EGV++ ++ Sbjct: 437 HNEIDEPRFTQPEMYDVIERHKRSVDIYVERLIKEGVISQDK 478 >UniRef50_Q387A7 Cluster: 2-oxoglutarate dehydrogenase subunit, putative; n=7; Trypanosomatidae|Rep: 2-oxoglutarate dehydrogenase subunit, putative - Trypanosoma brucei Length = 1008 Score = 102 bits (245), Expect = 6e-21 Identities = 39/85 (45%), Positives = 60/85 (70%) Frame = +2 Query: 254 DLPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVC 433 DL Y GT+HI+ NNQ+GFTTD +R + YC+D++++ P+ HVN ++ EA + Sbjct: 401 DLDNYRVGGTVHIITNNQVGFTTDSVDARRAKYCSDISKIHATPVLHVNSNDVEACVRAA 460 Query: 434 NVAAEWRATFHKDVVIDIVSYRRNG 508 +AA +R TFH+D++ID++ YRRNG Sbjct: 461 RIAARFRQTFHRDIIIDLIGYRRNG 485 Score = 68.9 bits (161), Expect = 1e-10 Identities = 36/82 (43%), Positives = 48/82 (58%) Frame = +3 Query: 6 GDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKVM 185 GD KYHLG ++ K I + NPSHLEA++P+V GK RA D+E + + Sbjct: 319 GDNKYHLGAD-RQIELRNGKVINFDLLCNPSHLEAMNPLVLGKARARMVVEKDSECVRTL 377 Query: 186 SILLHGDAAFAGQGVVFETMHL 251 I+ HGDAA +G G+ ETM L Sbjct: 378 PIIAHGDAAISGLGMGHETMGL 399 Score = 55.6 bits (128), Expect = 1e-06 Identities = 24/47 (51%), Positives = 34/47 (72%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDVK 648 +NE D P FTQP MYQ +R +P+++ Y+D L+ EGV+T E+VK K Sbjct: 486 HNEADFPDFTQPQMYQIVRSLRPLVDLYSDTLVEEGVLTKEDVKAKK 532 >UniRef50_Q8K9N3 Cluster: 2-oxoglutarate dehydrogenase E1 component; n=4; Enterobacteriaceae|Rep: 2-oxoglutarate dehydrogenase E1 component - Buchnera aphidicola subsp. Schizaphis graminum Length = 923 Score = 101 bits (243), Expect = 1e-20 Identities = 47/83 (56%), Positives = 62/83 (74%), Gaps = 1/83 (1%) Frame = +2 Query: 263 AYTTHGTIHIVANNQIGFTT-DPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCNV 439 AY GTIHIV NNQIGFTT +P++ RSS YCTDVA+++ AP+FHVN D+ EA + + Sbjct: 369 AYKIGGTIHIVINNQIGFTTSNPKNLRSSKYCTDVAKMIQAPVFHVNADDIEASIFAIQL 428 Query: 440 AAEWRATFHKDVVIDIVSYRRNG 508 A +++ F KDV ID+V YRR+G Sbjct: 429 ALKFKKKFKKDVFIDLVCYRRHG 451 Score = 69.3 bits (162), Expect = 7e-11 Identities = 40/84 (47%), Positives = 52/84 (61%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 182 SGDVKYH+G + N K I L + NPSHLE V+PVV G RA +E K Sbjct: 285 SGDVKYHMGGITKIKN--DKKKIYLKLAYNPSHLEIVNPVVLGIARASINQLKISENK-F 341 Query: 183 MSILLHGDAAFAGQGVVFETMHLS 254 +SI +HGDA+ GQGV+ ET+++S Sbjct: 342 LSINIHGDASIIGQGVIQETLNMS 365 Score = 45.2 bits (102), Expect = 0.001 Identities = 17/46 (36%), Positives = 33/46 (71%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDV 645 +NEVD+P TQP+MY+KI + + Y++ LI+E ++T+ +++ + Sbjct: 452 HNEVDDPFVTQPIMYKKIHNHPTIGQIYSNLLISEKLITSNDIEKI 497 >UniRef50_A7H8J4 Cluster: 2-oxoglutarate dehydrogenase, E1 subunit; n=2; Anaeromyxobacter|Rep: 2-oxoglutarate dehydrogenase, E1 subunit - Anaeromyxobacter sp. Fw109-5 Length = 940 Score = 101 bits (241), Expect = 2e-20 Identities = 45/105 (42%), Positives = 64/105 (60%) Frame = +2 Query: 254 DLPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVC 433 +L Y GTIH++ NNQ+GFTT PR +RS+ Y T AR++ PI HVNG++ EA+ Sbjct: 367 ELEGYAVGGTIHVIVNNQVGFTTSPRDARSTTYATGPARMLQIPIIHVNGEDLEAIAQAV 426 Query: 434 NVAAEWRATFHKDVVIDIVSYRRNGTTKSTNRCSLSPSCTRRFVR 568 +A ++R FH+DVVID+ +YRR+G + P R R Sbjct: 427 LLAVDFRQRFHRDVVIDLWTYRRHGHNEGDEPAFTQPVMYRAISR 471 Score = 79.0 bits (186), Expect = 9e-14 Identities = 40/83 (48%), Positives = 54/83 (65%) Frame = +3 Query: 6 GDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKVM 185 GDVKYHLG +R + L++ NPSHLE +D VVQG+ RA+Q D + + + Sbjct: 285 GDVKYHLGYSSDR-ESAEGVLVHLSLAFNPSHLEWIDTVVQGRVRAKQDRYRDTDRHRSL 343 Query: 186 SILLHGDAAFAGQGVVFETMHLS 254 IL+HGDAAFA QGVV E++ +S Sbjct: 344 PILVHGDAAFAAQGVVAESLQMS 366 Score = 46.8 bits (106), Expect = 5e-04 Identities = 23/47 (48%), Positives = 32/47 (68%), Gaps = 1/47 (2%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEK-YADQLIAEGVVTAEEVKDV 645 +NE DEP FTQP+MY+ I + KP L+ Y QL+ EG + A EV+ + Sbjct: 452 HNEGDEPAFTQPVMYRAISR-KPTLKALYGQQLVKEGTIAAGEVEQM 497 >UniRef50_A7CWX7 Cluster: Oxoglutarate dehydrogenase; n=1; Opitutaceae bacterium TAV2|Rep: Oxoglutarate dehydrogenase - Opitutaceae bacterium TAV2 Length = 384 Score = 101 bits (241), Expect = 2e-20 Identities = 51/84 (60%), Positives = 61/84 (72%), Gaps = 1/84 (1%) Frame = +3 Query: 6 GDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGD-NEGKKV 182 GDVKYHLG Y L T K I + + ANPSHLE V+PVV+GKTRA Q RGD E ++V Sbjct: 270 GDVKYHLG-YEAALETTTGKTIEVRLAANPSHLEIVNPVVEGKTRARQRIRGDATERRRV 328 Query: 183 MSILLHGDAAFAGQGVVFETMHLS 254 +L+HGDAAFAGQGVV ET++ S Sbjct: 329 CPLLIHGDAAFAGQGVVAETLNFS 352 Score = 37.1 bits (82), Expect = 0.36 Identities = 16/28 (57%), Positives = 19/28 (67%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPRHSR 340 L Y+T GT+H V N QIGFTT P +R Sbjct: 354 LTGYSTGGTLHFVINKQIGFTTLPSDAR 381 >UniRef50_UPI0000E46CA4 Cluster: PREDICTED: hypothetical protein, partial; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein, partial - Strongylocentrotus purpuratus Length = 244 Score = 100 bits (240), Expect = 3e-20 Identities = 42/88 (47%), Positives = 60/88 (68%) Frame = +2 Query: 245 APVDLPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVM 424 A +LP Y G+IH++ NNQIGFTT RSS Y +D+A++ P+ HVNG++PEAV+ Sbjct: 44 AMANLPHYAVGGSIHLIVNNQIGFTTPSERGRSSPYSSDIAKMNGNPVIHVNGEDPEAVL 103 Query: 425 HVCNVAAEWRATFHKDVVIDIVSYRRNG 508 C +A +R F KDVV+D++ +RR G Sbjct: 104 SACRLAVSYRQKFRKDVVVDLLCFRRWG 131 Score = 44.0 bits (99), Expect = 0.003 Identities = 20/49 (40%), Positives = 31/49 (63%), Gaps = 1/49 (2%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEV-KDVKD 651 +NE+D+P FTQP+MY I+ + + Y + EG V+ EEV K+V + Sbjct: 132 HNEIDDPSFTQPIMYGNIKSRLSIPDAYIQKTAEEGSVSKEEVDKNVSE 180 Score = 37.1 bits (82), Expect = 0.36 Identities = 15/23 (65%), Positives = 19/23 (82%) Frame = +3 Query: 171 GKKVMSILLHGDAAFAGQGVVFE 239 G KV+++LLHGDAAF QGV+ E Sbjct: 19 GDKVINVLLHGDAAFVAQGVIAE 41 >UniRef50_A3IFN6 Cluster: Alpha-ketoglutarate decarboxylase; n=1; Bacillus sp. B14905|Rep: Alpha-ketoglutarate decarboxylase - Bacillus sp. B14905 Length = 670 Score = 100 bits (240), Expect = 3e-20 Identities = 46/93 (49%), Positives = 62/93 (66%) Frame = +2 Query: 266 YTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCNVAA 445 +TT GTIHI+ANN IGFTT+ SRSS Y +D A+ P+ HVN D+PEAV V AA Sbjct: 393 FTTGGTIHIIANNMIGFTTEQYDSRSSVYSSDPAKGYEVPVVHVNADSPEAVAQVGRFAA 452 Query: 446 EWRATFHKDVVIDIVSYRRNGTTKSTNRCSLSP 544 +R F KD+V+D+V YRR+G ++ + +P Sbjct: 453 NYRQKFGKDIVVDLVGYRRHGHNETDDPTVTNP 485 Score = 68.1 bits (159), Expect = 2e-10 Identities = 40/89 (44%), Positives = 54/89 (60%), Gaps = 5/89 (5%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGD-----N 167 +GDVKYH+G NR + N++LA NPSHLE +PVV G TRA Q + Sbjct: 305 TGDVKYHMGA---SYNRDSGMNVKLAY--NPSHLEVGNPVVLGATRATQDDTSKPGQAIH 359 Query: 168 EGKKVMSILLHGDAAFAGQGVVFETMHLS 254 + K + IL+HGDAAF GQG+V E ++ + Sbjct: 360 DRTKGLGILVHGDAAFPGQGIVTEVLNFA 388 Score = 37.5 bits (83), Expect = 0.28 Identities = 16/43 (37%), Positives = 25/43 (58%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEV 636 +NE D+P T P Y+ + K + V Y L+ EG+V+ E+V Sbjct: 474 HNETDDPTVTNPETYKLVSKHETVRSLYGAALVTEGLVSTEDV 516 >UniRef50_Q6MC85 Cluster: Probable 2-oxoglutarate dehydrogenase E1 component, sucA; n=1; Candidatus Protochlamydia amoebophila UWE25|Rep: Probable 2-oxoglutarate dehydrogenase E1 component, sucA - Protochlamydia amoebophila (strain UWE25) Length = 890 Score = 99.5 bits (237), Expect = 6e-20 Identities = 46/84 (54%), Positives = 56/84 (66%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCN 436 L Y T GTIH V NNQIGFTT PR RS+ YCTD+AR PIFHVN ++P++ + V Sbjct: 336 LKGYETGGTIHFVINNQIGFTTIPRDLRSTRYCTDIARAFGLPIFHVNAEDPDSCVQVTL 395 Query: 437 VAAEWRATFHKDVVIDIVSYRRNG 508 +A E R FH DV ID+ YR+ G Sbjct: 396 LALEIRQRFHCDVFIDLNGYRKYG 419 Score = 95.9 bits (228), Expect = 7e-19 Identities = 45/84 (53%), Positives = 63/84 (75%), Gaps = 1/84 (1%) Frame = +3 Query: 6 GDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEG-KKV 182 GDVKYH G E++ K+I++++ NPSHLE+V+ VV+GKTRA+QF G + KK+ Sbjct: 251 GDVKYHKGYTGEKIKTRLGKSIKISLSPNPSHLESVNAVVEGKTRAKQFLAGGEKARKKI 310 Query: 183 MSILLHGDAAFAGQGVVFETMHLS 254 + IL+HGDAA +GQGVV+ET+ LS Sbjct: 311 IPILIHGDAAVSGQGVVYETLQLS 334 Score = 37.5 bits (83), Expect = 0.28 Identities = 15/38 (39%), Positives = 26/38 (68%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVV 621 +NE DEP +TQPL + I+ + + + Y DQL+ +G++ Sbjct: 420 HNEGDEPAYTQPLECRLIKGKQSIRKMYYDQLLVQGIL 457 >UniRef50_Q23KH1 Cluster: 2-oxoglutarate dehydrogenase, E1 component family protein; n=1; Tetrahymena thermophila SB210|Rep: 2-oxoglutarate dehydrogenase, E1 component family protein - Tetrahymena thermophila SB210 Length = 992 Score = 99.1 bits (236), Expect = 8e-20 Identities = 43/85 (50%), Positives = 57/85 (67%) Frame = +2 Query: 254 DLPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVC 433 +L Y+ G +HI+ NNQIGFTT P R+ Y TDV + V +PIFHVN D P+ V V Sbjct: 398 ELVGYSPRGIVHIIVNNQIGFTTTPAEYRTGLYSTDVMKSVESPIFHVNADEPDLVDAVF 457 Query: 434 NVAAEWRATFHKDVVIDIVSYRRNG 508 +A ++R TFHKDV++DI+ YR G Sbjct: 458 RLAVDYRNTFHKDVMVDIIGYRLFG 482 Score = 95.9 bits (228), Expect = 7e-19 Identities = 41/83 (49%), Positives = 62/83 (74%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 182 SGDVKYHLG E++N + K I++++ NPSHLE V+PV G RA Q ++GD+ G K Sbjct: 315 SGDVKYHLGCTTEKVNP-SGKKIKMSILPNPSHLETVNPVTMGCVRAVQDFKGDSTGLKT 373 Query: 183 MSILLHGDAAFAGQGVVFETMHL 251 + +L+HGD++F+GQGVV+E++ + Sbjct: 374 LGVLVHGDSSFSGQGVVYESLQM 396 Score = 61.3 bits (142), Expect = 2e-08 Identities = 24/47 (51%), Positives = 37/47 (78%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDVK 648 +NE+DEP FTQP+MY KI K PV +KY+ +L+ EGV+T E+++++ Sbjct: 483 HNELDEPRFTQPMMYSKIEKMTPVYQKYSKRLLDEGVITQAEIEELE 529 >UniRef50_A4CGF1 Cluster: 2-oxoglutarate dehydrogenase, E1 component; n=16; cellular organisms|Rep: 2-oxoglutarate dehydrogenase, E1 component - Robiginitalea biformata HTCC2501 Length = 940 Score = 98.7 bits (235), Expect = 1e-19 Identities = 43/84 (51%), Positives = 57/84 (67%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCN 436 L Y T GTIHIV NNQIGFTT+ R+S YCTDV +V +P+ H+N D+ EAV+H Sbjct: 365 LDGYGTAGTIHIVVNNQIGFTTNYLDGRTSTYCTDVGKVTLSPVLHINADDAEAVVHAAL 424 Query: 437 VAAEWRATFHKDVVIDIVSYRRNG 508 A E+R F +DV +D++ YR+ G Sbjct: 425 FALEYRMKFRRDVFLDLLGYRKYG 448 Score = 76.2 bits (179), Expect = 6e-13 Identities = 38/84 (45%), Positives = 55/84 (65%), Gaps = 1/84 (1%) Frame = +3 Query: 6 GDVKYHLG-TYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 182 GDVKYHLG T + + N + +I + + NPSHLE V VV+G TRA+Q + KV Sbjct: 282 GDVKYHLGWTSMRKTN--SGDSINMNIAPNPSHLETVGAVVEGITRAKQDRHFPEDFSKV 339 Query: 183 MSILLHGDAAFAGQGVVFETMHLS 254 + I++HGDAA AGQG+ +E + ++ Sbjct: 340 LPIVVHGDAAIAGQGIAYEVVQMA 363 Score = 47.6 bits (108), Expect = 3e-04 Identities = 21/48 (43%), Positives = 35/48 (72%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDVKD 651 +NE DEP FTQP +Y+ I K + + YA++L++EGV+ A+ VK +++ Sbjct: 449 HNEGDEPRFTQPKLYKAIAKHQNPRDIYAERLMSEGVIDADFVKKLEE 496 >UniRef50_Q81TK1 Cluster: 2-oxoglutarate dehydrogenase E1 component; n=20; Bacillaceae|Rep: 2-oxoglutarate dehydrogenase E1 component - Bacillus anthracis Length = 955 Score = 98.7 bits (235), Expect = 1e-19 Identities = 44/101 (43%), Positives = 64/101 (63%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCN 436 L AY T GTIH++ANN +GFTTD SRS+ Y +D+A+ + PI HVN D+PEA + N Sbjct: 375 LNAYQTGGTIHVIANNAVGFTTDSYDSRSTKYSSDLAKGFDIPIVHVNADDPEACLAAAN 434 Query: 437 VAAEWRATFHKDVVIDIVSYRRNGTTKSTNRCSLSPSCTRR 559 +A ++R F KD +ID++ YRR G + + P ++ Sbjct: 435 LAIQYRMLFKKDFLIDLIGYRRYGHNEMDDPAVTQPQVYKK 475 Score = 73.7 bits (173), Expect = 3e-12 Identities = 44/91 (48%), Positives = 58/91 (63%), Gaps = 7/91 (7%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNI--RLAVCANPSHLEAVDPVVQGKTRAEQFYRG----- 161 +GDVKYHLG R V+N+ + R+ + NPSHLE V+PVV+G RA Q R Sbjct: 287 TGDVKYHLG----REQVVSNEEVSTRVTLANNPSHLEFVNPVVEGFARAAQENRKKSGLP 342 Query: 162 DNEGKKVMSILLHGDAAFAGQGVVFETMHLS 254 + + K IL+HGDAAF GQG+V ET++LS Sbjct: 343 EQDTSKSFVILVHGDAAFPGQGIVSETLNLS 373 Score = 48.0 bits (109), Expect = 2e-04 Identities = 21/46 (45%), Positives = 32/46 (69%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDV 645 +NE+D+P TQP +Y+KI+ V YADQL A GV+ A+E++ + Sbjct: 459 HNEMDDPAVTQPQVYKKIKNHPTVRAIYADQLQAAGVLNADEIETI 504 >UniRef50_Q1IKU2 Cluster: 2-oxoglutarate dehydrogenase, E1 component; n=1; Acidobacteria bacterium Ellin345|Rep: 2-oxoglutarate dehydrogenase, E1 component - Acidobacteria bacterium (strain Ellin345) Length = 820 Score = 97.9 bits (233), Expect = 2e-19 Identities = 41/101 (40%), Positives = 66/101 (65%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCN 436 LP + GT+H++ANN IGFT +PR + SS Y +D+A+ + PI HVN ++P+AV+ V Sbjct: 268 LPGFDIGGTVHVIANNLIGFTANPREAYSSRYSSDIAKRLEMPIIHVNAEDPDAVVRVGR 327 Query: 437 VAAEWRATFHKDVVIDIVSYRRNGTTKSTNRCSLSPSCTRR 559 +A E+R F DV++D++ YRR+G ++ + P R+ Sbjct: 328 IAMEYRDRFQSDVLVDLIGYRRHGHSEVDDPTITQPIVYRK 368 Score = 80.2 bits (189), Expect = 4e-14 Identities = 36/82 (43%), Positives = 57/82 (69%) Frame = +3 Query: 6 GDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKVM 185 GDVKYH+G+ + + + + + + +NPSHLEAV+PV G+ +A+Q G+ KV+ Sbjct: 185 GDVKYHIGSTGD-YHAANGQTVHIHLASNPSHLEAVNPVAAGRVKAKQQRIGEGGIPKVV 243 Query: 186 SILLHGDAAFAGQGVVFETMHL 251 +++HGD AFAGQG+V ET++L Sbjct: 244 PLIMHGDTAFAGQGIVAETLNL 265 Score = 37.9 bits (84), Expect = 0.21 Identities = 17/44 (38%), Positives = 29/44 (65%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVK 639 ++EVD+P TQP++Y+KI+ + E YA ++ A+ AE V+ Sbjct: 352 HSEVDDPTITQPIVYRKIKDMPLISESYAAKIGADTKPMAEAVQ 395 >UniRef50_Q4UKI8 Cluster: 2-oxoglutarate dehydrogenase E1 component; n=14; Rickettsia|Rep: 2-oxoglutarate dehydrogenase E1 component - Rickettsia felis (Rickettsia azadi) Length = 977 Score = 97.9 bits (233), Expect = 2e-19 Identities = 48/84 (57%), Positives = 61/84 (72%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 182 SGDVKYHLG +R + NK I L++ NPSHLEAV+P+V GK RA+Q GD + KV Sbjct: 336 SGDVKYHLGYSSDRT--IDNKKIHLSLADNPSHLEAVNPIVAGKVRAKQDILGDTKRSKV 393 Query: 183 MSILLHGDAAFAGQGVVFETMHLS 254 +IL+HGDAAF GQGVV E++ +S Sbjct: 394 KAILVHGDAAFCGQGVVAESLSMS 417 Score = 94.7 bits (225), Expect = 2e-18 Identities = 41/84 (48%), Positives = 58/84 (69%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCN 436 L AY G +H V NNQ+GFT + +R+S Y T+ A+++ API HVNGD+ EAV+ N Sbjct: 419 LAAYDIGGILHFVINNQLGFTANAADTRASRYSTEFAKIIAAPILHVNGDDIEAVLKATN 478 Query: 437 VAAEWRATFHKDVVIDIVSYRRNG 508 +A E+R F KDVV++I+ YR+ G Sbjct: 479 IAVEYRQKFGKDVVVEIICYRKYG 502 Score = 35.1 bits (77), Expect = 1.5 Identities = 18/39 (46%), Positives = 26/39 (66%), Gaps = 1/39 (2%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEK-YADQLIAEGVV 621 +NE DEPM+TQ MY I K+KP YA++L+ G++ Sbjct: 503 HNEGDEPMYTQGKMY-NIIKSKPTPGNIYANELVKSGII 540 >UniRef50_A0FRW7 Cluster: 2-oxoglutarate dehydrogenase, E1 subunit; n=2; Burkholderiaceae|Rep: 2-oxoglutarate dehydrogenase, E1 subunit - Burkholderia phymatum STM815 Length = 891 Score = 97.1 bits (231), Expect = 3e-19 Identities = 40/82 (48%), Positives = 58/82 (70%), Gaps = 1/82 (1%) Frame = +2 Query: 266 YTTHGTIHIVANNQIGFTT-DPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCNVA 442 YT GTIH++ NNQIGFTT +P ++YCTD+AR++++P+ HVN D PE V+ +A Sbjct: 341 YTLGGTIHVIVNNQIGFTTPNPMSVHDNSYCTDIARMIDSPVIHVNADYPEDVIRAARIA 400 Query: 443 AEWRATFHKDVVIDIVSYRRNG 508 ++R + DVVID++ YRR G Sbjct: 401 FDYRMRYEADVVIDLIGYRRLG 422 Score = 66.5 bits (155), Expect = 5e-10 Identities = 34/82 (41%), Positives = 52/82 (63%) Frame = +3 Query: 9 DVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKVMS 188 D+ YHLG L R + I L + NPSHL++V PVV G RA ++ ++ + Sbjct: 260 DLPYHLGG--AALKRTAHGEIALLLAHNPSHLQSVYPVVSGMARA---WQDEHLDAACVP 314 Query: 189 ILLHGDAAFAGQGVVFETMHLS 254 +++HGDAAFAGQG+V ET++++ Sbjct: 315 VVVHGDAAFAGQGIVMETLNMT 336 >UniRef50_Q5L172 Cluster: 2-oxoglutarate dehydrogenase E1 component; n=8; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1 component - Geobacillus kaustophilus Length = 950 Score = 96.3 bits (229), Expect = 6e-19 Identities = 45/97 (46%), Positives = 61/97 (62%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCN 436 L YTT GTIHI+ANN IGFTT+ SRS+ Y +D+A+ PI HVN D+PEA + Sbjct: 388 LRGYTTGGTIHIIANNMIGFTTESYDSRSTTYASDMAKGFEVPIVHVNADDPEACLAAAC 447 Query: 437 VAAEWRATFHKDVVIDIVSYRRNGTTKSTNRCSLSPS 547 +A +R F KD VID++ YRR G + + +P+ Sbjct: 448 LAFAYRQRFKKDFVIDLIGYRRFGHNEMDEPMATNPT 484 Score = 76.6 bits (180), Expect = 5e-13 Identities = 45/90 (50%), Positives = 56/90 (62%), Gaps = 6/90 (6%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 182 +GDVKYHLG RL + +R+ + NPSHLE V+PVV G TRA Q R G V Sbjct: 299 TGDVKYHLGA-ARRLRNQSAHTMRITLANNPSHLEVVNPVVLGYTRAAQEDR-TKPGVPV 356 Query: 183 MS------ILLHGDAAFAGQGVVFETMHLS 254 + IL+HGDAAF GQG+V ET++LS Sbjct: 357 QNTDASFAILIHGDAAFPGQGIVAETLNLS 386 Score = 44.4 bits (100), Expect = 0.002 Identities = 19/47 (40%), Positives = 31/47 (65%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDVK 648 +NE+DEPM T P MY I + V + YA +L+ +G++T EV +++ Sbjct: 472 HNEMDEPMATNPTMYAIINQHPTVRKLYAQKLMEKGIITEREVDEME 518 >UniRef50_Q7VR91 Cluster: 2-oxoglutarate dehydrogenase E1 component; n=2; Candidatus Blochmannia|Rep: 2-oxoglutarate dehydrogenase E1 component - Blochmannia floridanus Length = 970 Score = 94.7 bits (225), Expect = 2e-18 Identities = 45/83 (54%), Positives = 57/83 (68%), Gaps = 1/83 (1%) Frame = +2 Query: 263 AYTTHGTIHIVANNQIGFTTDPRHS-RSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCNV 439 AY+ GTIHIV NNQIGFTT RS+ YCTD+A+++ API HVN D+ AV+ V Sbjct: 404 AYSVGGTIHIVINNQIGFTTSNIDDIRSTPYCTDIAKMIQAPILHVNADDVHAVIFVTRF 463 Query: 440 AAEWRATFHKDVVIDIVSYRRNG 508 A +R F D+VID+V YRR+G Sbjct: 464 ALNFRNKFKHDIVIDLVCYRRHG 486 Score = 64.1 bits (149), Expect = 3e-09 Identities = 39/97 (40%), Positives = 57/97 (58%), Gaps = 13/97 (13%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRA--EQFYRGD---- 164 SGDVKYH G Y E + ++ + +++ NPSHLE + PV+ G RA EQ Y+ Sbjct: 306 SGDVKYHQGLYSEVT--INSQIVHISLLFNPSHLEIITPVMMGAARARIEQLYKDQIHKT 363 Query: 165 --NEGKK-----VMSILLHGDAAFAGQGVVFETMHLS 254 N+ K V+ I +HGDAA + QGVV ET++++ Sbjct: 364 ILNKNYKIQQNIVLPITIHGDAAISAQGVVQETLNMA 400 Score = 53.6 bits (123), Expect = 4e-06 Identities = 22/45 (48%), Positives = 32/45 (71%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKD 642 +NE DEP TQP+MYQKIR VLE YA +LI + ++ +++K+ Sbjct: 487 HNETDEPHVTQPMMYQKIRNHPTVLELYAQKLIQKNIINVDDIKN 531 >UniRef50_Q4RSE1 Cluster: Chromosome 13 SCAF15000, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 13 SCAF15000, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 974 Score = 94.3 bits (224), Expect = 2e-18 Identities = 39/97 (40%), Positives = 61/97 (62%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCN 436 LP Y G+IH++ NNQ+G+TT RSS YC+DV ++V+ + HVNGD+ E V+ Sbjct: 352 LPHYRVGGSIHLIVNNQVGYTTPSERGRSSFYCSDVGKMVDCAVIHVNGDHAEEVLRATR 411 Query: 437 VAAEWRATFHKDVVIDIVSYRRNGTTKSTNRCSLSPS 547 +A E++ F KDV++D++ YR+ G + +PS Sbjct: 412 LAVEYQRLFRKDVILDLICYRQWGHNELDEPFFTNPS 448 Score = 70.9 bits (166), Expect = 2e-11 Identities = 41/92 (44%), Positives = 56/92 (60%), Gaps = 9/92 (9%) Frame = +3 Query: 6 GDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYR--GD----- 164 GDV HL + +E L+ + + + + NPSHLEA+DPV QGKTRA Q R GD Sbjct: 260 GDVLSHLTSSVE-LDFGAGRPLHVTMLPNPSHLEAIDPVAQGKTRARQQLRKEGDYSPED 318 Query: 165 --NEGKKVMSILLHGDAAFAGQGVVFETMHLS 254 G +V+ + +HGD +F GQG+V ET+ LS Sbjct: 319 AAQPGDQVICLQVHGDGSFTGQGIVAETLTLS 350 Score = 58.0 bits (134), Expect = 2e-07 Identities = 26/47 (55%), Positives = 34/47 (72%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDVK 648 +NE+DEP FT P MY+ IR K V + YADQLI+EG++T E D+K Sbjct: 436 HNELDEPFFTNPSMYKIIRSRKSVPDSYADQLISEGLMTEAEHDDIK 482 >UniRef50_Q96HY7 Cluster: Dehydrogenase E1 and transketolase domain-containing protein 1; n=39; Eumetazoa|Rep: Dehydrogenase E1 and transketolase domain-containing protein 1 - Homo sapiens (Human) Length = 919 Score = 93.5 bits (222), Expect = 4e-18 Identities = 37/85 (43%), Positives = 58/85 (68%) Frame = +2 Query: 254 DLPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVC 433 +LP + G++H++ NNQ+G+TT RSS YC+D+ ++V I HVNGD+PE V+ Sbjct: 350 NLPHFRIGGSVHLIVNNQLGYTTPAERGRSSLYCSDIGKLVGCAIIHVNGDSPEEVVRAT 409 Query: 434 NVAAEWRATFHKDVVIDIVSYRRNG 508 +A E++ F KDV+ID++ YR+ G Sbjct: 410 RLAFEYQRQFRKDVIIDLLCYRQWG 434 Score = 63.7 bits (148), Expect = 4e-09 Identities = 38/93 (40%), Positives = 54/93 (58%), Gaps = 9/93 (9%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNE---- 170 +GDV HL + ++ L + + + + NPSHLEAV+PV GKTR Q R D + Sbjct: 258 TGDVLSHLTSSVD-LYFGAHHPLHVTMLPNPSHLEAVNPVAVGKTRGRQQSRQDGDYSPD 316 Query: 171 -----GKKVMSILLHGDAAFAGQGVVFETMHLS 254 G +V+ + +HGDA+F GQG+V ET LS Sbjct: 317 NSAQPGDRVICLQVHGDASFCGQGIVPETFTLS 349 Score = 56.0 bits (129), Expect = 7e-07 Identities = 23/47 (48%), Positives = 35/47 (74%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDVK 648 +NE+DEP +T P+MY+ IR K + + YA+ LIA G++T EEV ++K Sbjct: 435 HNELDEPFYTNPIMYKIIRARKSIPDTYAEHLIAGGLMTQEEVSEIK 481 >UniRef50_Q5L672 Cluster: 2-oxoglutarate dehydrogenase E1 component; n=7; Chlamydiaceae|Rep: 2-oxoglutarate dehydrogenase E1 component - Chlamydophila abortus Length = 908 Score = 92.7 bits (220), Expect = 7e-18 Identities = 39/96 (40%), Positives = 60/96 (62%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCN 436 +P Y+T GT+HI+ NN IGFT PR SRS+ YCTD+A+++ P+F VN ++ A + Sbjct: 346 IPGYSTGGTLHIIVNNHIGFTAQPRESRSTPYCTDIAKMLGIPVFRVNAEDVVACLQAIE 405 Query: 437 VAAEWRATFHKDVVIDIVSYRRNGTTKSTNRCSLSP 544 + + R F DV+ID+ YR+ G +S + +P Sbjct: 406 YSLKVREEFSCDVIIDLCCYRKYGHNESDDPSITAP 441 Score = 81.8 bits (193), Expect = 1e-14 Identities = 41/83 (49%), Positives = 53/83 (63%) Frame = +3 Query: 6 GDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKVM 185 GDVKYH G Y+ R + + + NPSHLEAVDPVV+G A Q + + Sbjct: 263 GDVKYHKG-YVSRSFGQHGEEVTFVMLPNPSHLEAVDPVVEGVVAALQHQVDAGKEHSCL 321 Query: 186 SILLHGDAAFAGQGVVFETMHLS 254 +IL+HGDAAF+GQGVV+ET+ LS Sbjct: 322 AILVHGDAAFSGQGVVYETLQLS 344 >UniRef50_Q8IGV6 Cluster: RE22749p; n=7; Diptera|Rep: RE22749p - Drosophila melanogaster (Fruit fly) Length = 919 Score = 91.5 bits (217), Expect = 2e-17 Identities = 37/84 (44%), Positives = 59/84 (70%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCN 436 +P + G++H++ NNQ+GFTT RS+AY +D+A+ + AP+FHVNGD+PEA+ V + Sbjct: 351 VPHFEVGGSLHLIVNNQVGFTTPGDRGRSTAYTSDLAKSIQAPVFHVNGDDPEALARVTS 410 Query: 437 VAAEWRATFHKDVVIDIVSYRRNG 508 +A ++ F KD+ ID+ +RR G Sbjct: 411 LAFRYQREFRKDIFIDLNCFRRWG 434 Score = 66.1 bits (154), Expect = 7e-10 Identities = 31/76 (40%), Positives = 50/76 (65%), Gaps = 8/76 (10%) Frame = +3 Query: 51 RVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNE--------GKKVMSILLHGD 206 ++ K + ++ NPSHLEA +PV GKTR++Q RG+ G+ V++++LHGD Sbjct: 274 KILGKKLSFSMVRNPSHLEAANPVAMGKTRSKQQARGEGAFGDGSQPFGEHVLNVILHGD 333 Query: 207 AAFAGQGVVFETMHLS 254 AAFAGQG+ E ++++ Sbjct: 334 AAFAGQGINQECLNMA 349 Score = 45.2 bits (102), Expect = 0.001 Identities = 18/48 (37%), Positives = 33/48 (68%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDVKD 651 +NE+D+P FT PL+Y+ + + + V + YA QL E V++ + K+++D Sbjct: 435 HNELDDPTFTNPLVYKIVHQRESVPDLYAQQLAKEQVLSESKAKEMRD 482 >UniRef50_A5CEI8 Cluster: 2-oxoglutarate dehydrogenase, E1 component; n=1; Orientia tsutsugamushi Boryong|Rep: 2-oxoglutarate dehydrogenase, E1 component - Orientia tsutsugamushi (strain Boryong) (Rickettsia tsutsugamushi) Length = 963 Score = 91.1 bits (216), Expect = 2e-17 Identities = 40/84 (47%), Positives = 54/84 (64%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCN 436 L Y G +H + NNQIGFT + Y T+VA+ + APIFHVNGD+PE+V+ + Sbjct: 393 LKPYAAGGILHYIINNQIGFTANTDEIYPGQYTTEVAKTIKAPIFHVNGDDPESVLKITA 452 Query: 437 VAAEWRATFHKDVVIDIVSYRRNG 508 +A +R F KDVVIDI+ YR+ G Sbjct: 453 IAMAYRQKFAKDVVIDIICYRKYG 476 Score = 89.8 bits (213), Expect = 5e-17 Identities = 47/84 (55%), Positives = 60/84 (71%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 182 SGDVKYH+G + N NI++++ NPSHLEAV+ VV GK RA+Q D E K+V Sbjct: 310 SGDVKYHMG--YSGVYTGKNNNIKISLTPNPSHLEAVNSVVAGKVRAKQDDLEDIERKQV 367 Query: 183 MSILLHGDAAFAGQGVVFETMHLS 254 M IL+HGDAAF+GQGVV E++ LS Sbjct: 368 MGILIHGDAAFSGQGVVAESLLLS 391 Score = 42.7 bits (96), Expect = 0.007 Identities = 20/48 (41%), Positives = 29/48 (60%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDVKD 651 +NE DEPMFTQ MY I+ V E YA +LI + + + +D+K+ Sbjct: 477 HNEGDEPMFTQASMYNVIKNKVSVTELYAQKLINQKFILESDYQDMKN 524 >UniRef50_Q23629 Cluster: Putative uncharacterized protein; n=3; Bilateria|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 911 Score = 89.4 bits (212), Expect = 6e-17 Identities = 40/95 (42%), Positives = 57/95 (60%) Frame = +2 Query: 260 PAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCNV 439 P + GT+H+V NNQI FT + RSS +CTD+A+ P+ HVNGD+PE V+ + Sbjct: 342 PHFRLGGTVHLVTNNQIAFTAESSVGRSSTHCTDIAKAFEYPVIHVNGDHPEEVVKATRL 401 Query: 440 AAEWRATFHKDVVIDIVSYRRNGTTKSTNRCSLSP 544 A +R F KDV I++V +RR G + + SP Sbjct: 402 ALAYRERFRKDVFINLVCFRRWGHNELDDPTFTSP 436 Score = 64.9 bits (151), Expect = 2e-09 Identities = 38/94 (40%), Positives = 56/94 (59%), Gaps = 10/94 (10%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFY--RGD---- 164 +GDV HL + + + + N+ + + NPSHLEAV+PV GK RA + +GD Sbjct: 248 AGDVLSHLVSSFDY--KGSEGNVHVTMLPNPSHLEAVNPVAMGKARARAWSMNKGDYSPD 305 Query: 165 ----NEGKKVMSILLHGDAAFAGQGVVFETMHLS 254 G V+++L+HGD AF GQGVV+E++ LS Sbjct: 306 ERSARAGDSVLNVLVHGDGAFTGQGVVWESIALS 339 Score = 46.0 bits (104), Expect = 8e-04 Identities = 18/45 (40%), Positives = 30/45 (66%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKD 642 +NE+D+P FT P+MY+++ + V + D+L+ EG T E VK+ Sbjct: 425 HNELDDPTFTSPVMYKEVEARESVPRLFLDRLVEEGFTTEEAVKE 469 >UniRef50_A7AW62 Cluster: 2-oxoglutarate dehydrogenase E1 component , putative; n=1; Babesia bovis|Rep: 2-oxoglutarate dehydrogenase E1 component , putative - Babesia bovis Length = 891 Score = 89.4 bits (212), Expect = 6e-17 Identities = 40/84 (47%), Positives = 55/84 (65%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCN 436 +P YT GTI+IV NNQIGFTT P S+ Y TD+A++V +P H N N EAV+ Sbjct: 316 IPEYTVGGTINIVVNNQIGFTTYPSGGASTRYTTDIAKMVESPALHANAHNVEAVVLASR 375 Query: 437 VAAEWRATFHKDVVIDIVSYRRNG 508 +A E+R F KDV +D++ +R+ G Sbjct: 376 LAFEYRQKFGKDVFVDLIGFRKFG 399 Score = 73.3 bits (172), Expect = 5e-12 Identities = 38/83 (45%), Positives = 53/83 (63%) Frame = +3 Query: 6 GDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKVM 185 GDVKYH G +R N+ + + NPSHL+ V PVV GK RA Q + E +V+ Sbjct: 239 GDVKYHFGYSSKR------GNLHVDMLNNPSHLQFVHPVVAGKARARQVI-SNLESTRVL 291 Query: 186 SILLHGDAAFAGQGVVFETMHLS 254 ++LHGDAAF+G+GV +ET+ +S Sbjct: 292 PVVLHGDAAFSGEGVTYETVQMS 314 Score = 37.5 bits (83), Expect = 0.28 Identities = 18/43 (41%), Positives = 25/43 (58%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEV 636 +NE+D P FT MY +I K + VL Y L++ GV T E+ Sbjct: 400 HNELDMPKFTNAEMYARIEKKEDVLVAYRKFLLSHGVFTEPEL 442 >UniRef50_Q6MJP2 Cluster: Oxoglutarate dehydrogenase; n=1; Bdellovibrio bacteriovorus|Rep: Oxoglutarate dehydrogenase - Bdellovibrio bacteriovorus Length = 901 Score = 86.6 bits (205), Expect = 5e-16 Identities = 35/82 (42%), Positives = 58/82 (70%) Frame = +2 Query: 263 AYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCNVA 442 +++T GTIHI+ +NQ+GFTT + +RS+ Y +D A++ P+ HVNGD+ E+ + ++A Sbjct: 341 SHSTGGTIHIIIDNQVGFTTSGKDTRSTRYASDAAKMTFTPVLHVNGDDVESAVRAMDIA 400 Query: 443 AEWRATFHKDVVIDIVSYRRNG 508 +R F KDVVI+++ YR+ G Sbjct: 401 LRYRQEFGKDVVINLLCYRKYG 422 Score = 74.1 bits (174), Expect = 3e-12 Identities = 39/82 (47%), Positives = 50/82 (60%) Frame = +3 Query: 9 DVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKVMS 188 DVKYHLG E+ + LA NPSHLE V+ V G RA Q G + K V+ Sbjct: 258 DVKYHLGYVTEKKTPTGTCKVTLAY--NPSHLETVNAVALGMARAAQDQIGASGKKNVVP 315 Query: 189 ILLHGDAAFAGQGVVFETMHLS 254 +L+HGDAAFAGQG+V ET+ ++ Sbjct: 316 VLIHGDAAFAGQGIVQETLQMA 337 Score = 44.8 bits (101), Expect = 0.002 Identities = 22/46 (47%), Positives = 30/46 (65%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVKDV 645 +NE DEP FTQP MY+ I+ V E +A +L AEG V A+ +D+ Sbjct: 423 HNEGDEPAFTQPQMYELIKTHATVRELFAKKLAAEGSVDAKTSEDL 468 >UniRef50_Q54VG0 Cluster: Oxoglutarate dehydrogenase; n=1; Dictyostelium discoideum AX4|Rep: Oxoglutarate dehydrogenase - Dictyostelium discoideum AX4 Length = 900 Score = 86.2 bits (204), Expect = 6e-16 Identities = 40/83 (48%), Positives = 55/83 (66%) Frame = +3 Query: 6 GDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKVM 185 GDV H+ + +++ +++ NPSHLEAVDPV GKTRA+QFY + G + + Sbjct: 238 GDVTSHIAVSTDLQFNNNKESVHVSLIHNPSHLEAVDPVAAGKTRAKQFYEKNEGGSESL 297 Query: 186 SILLHGDAAFAGQGVVFETMHLS 254 ++LHGDAA AGQGVV ET+ LS Sbjct: 298 CLMLHGDAAVAGQGVVTETLQLS 320 Score = 85.8 bits (203), Expect = 8e-16 Identities = 35/84 (41%), Positives = 54/84 (64%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCN 436 L + G +H++ NNQIGFTT P + RS+ Y +D+ + + API VN +PE V V Sbjct: 322 LSGFNIGGCVHVIVNNQIGFTTVPTNGRSNRYSSDIGKFIGAPIIVVNSQSPEQVEKVSR 381 Query: 437 VAAEWRATFHKDVVIDIVSYRRNG 508 +A E+R F KD++ID++ +R+ G Sbjct: 382 LAVEYRQKFKKDIIIDLIGWRKFG 405 Score = 57.2 bits (132), Expect = 3e-07 Identities = 23/43 (53%), Positives = 34/43 (79%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEEV 636 +NEVDEP FTQP MYQ IRK + + +KYA Q+I++G+ + +E+ Sbjct: 406 HNEVDEPSFTQPTMYQNIRKRQSIPQKYATQIISQGIFSEQEL 448 >UniRef50_A0BCX8 Cluster: Chromosome undetermined scaffold_10, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_10, whole genome shotgun sequence - Paramecium tetraurelia Length = 893 Score = 86.2 bits (204), Expect = 6e-16 Identities = 39/84 (46%), Positives = 55/84 (65%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCN 436 L Y+ GT+HI+ NNQIG+TT+ + SR S Y +D+ PI HVNG++ E + V Sbjct: 323 LDNYSNGGTVHIIQNNQIGYTTNIKDSRFSRYSSDLLLAYRYPILHVNGEDVETLHKVSK 382 Query: 437 VAAEWRATFHKDVVIDIVSYRRNG 508 A E+R F KD++IDIV+YR+ G Sbjct: 383 FAVEYRQKFKKDILIDIVTYRKYG 406 Score = 77.8 bits (183), Expect = 2e-13 Identities = 40/82 (48%), Positives = 59/82 (71%) Frame = +3 Query: 9 DVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKVMS 188 DV +HL T ++ + NK++ + V NPSHLEA +PV QGK +A+Q G+ + +V++ Sbjct: 244 DVVHHLSTSNKK--KFNNKDLTITVVHNPSHLEAANPVSQGKAKAKQDDYGNID--QVLN 299 Query: 189 ILLHGDAAFAGQGVVFETMHLS 254 + LHGDAAFAGQG+V+E+M LS Sbjct: 300 LQLHGDAAFAGQGIVYESMLLS 321 Score = 44.4 bits (100), Expect = 0.002 Identities = 19/31 (61%), Positives = 23/31 (74%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQ 600 +NEVDEP FTQP MY+K+RK K + KY Q Sbjct: 407 HNEVDEPSFTQPNMYEKVRKAKSLPVKYNQQ 437 >UniRef50_Q4MZ92 Cluster: 2-oxoglutarate dehydrogenase e1 component, putative; n=2; Theileria|Rep: 2-oxoglutarate dehydrogenase e1 component, putative - Theileria parva Length = 1030 Score = 75.8 bits (178), Expect = 8e-13 Identities = 35/77 (45%), Positives = 52/77 (67%) Frame = +2 Query: 278 GTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCNVAAEWRA 457 GTI+I+ NNQIGFT + + +S Y +DV +V++API HVN + E+VM +A ++R Sbjct: 403 GTINIIVNNQIGFTANQLEASTSRYPSDVGKVIDAPIIHVNAYSIESVMFAGKLATKYRY 462 Query: 458 TFHKDVVIDIVSYRRNG 508 F DV I++V +RR G Sbjct: 463 KFKNDVFINLVGFRRFG 479 Score = 67.3 bits (157), Expect = 3e-10 Identities = 30/84 (35%), Positives = 50/84 (59%) Frame = +3 Query: 3 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 182 SGDVKYH G R T + + + +N SHL+ PV+ G +A+Q+Y D K+ Sbjct: 317 SGDVKYHNGY------RTTKNGVEIQMISNSSHLQFSHPVLTGLVKAKQYYENDTNQSKI 370 Query: 183 MSILLHGDAAFAGQGVVFETMHLS 254 + I +HG++A +GQG+ +E + ++ Sbjct: 371 LPIAIHGNSAISGQGMPYEVVQMA 394 >UniRef50_Q2UQN4 Cluster: RIB40 genomic DNA, SC005; n=1; Aspergillus oryzae|Rep: RIB40 genomic DNA, SC005 - Aspergillus oryzae Length = 453 Score = 69.3 bits (162), Expect = 7e-11 Identities = 36/83 (43%), Positives = 51/83 (61%) Frame = +3 Query: 6 GDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKVM 185 GD+KYH G ER+ + K + + V PSHL++V+PV GKTR Q D E + M Sbjct: 275 GDIKYHYGGSGERVTP-SGKKVYMNVLPQPSHLDSVNPVAMGKTRGIQDRLAD-ERESTM 332 Query: 186 SILLHGDAAFAGQGVVFETMHLS 254 + +H DA+FA QG ++ET+ LS Sbjct: 333 MLNVHTDASFAAQGTIYETLGLS 355 Score = 41.5 bits (93), Expect = 0.017 Identities = 15/23 (65%), Positives = 19/23 (82%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTD 325 LP YTT GT+ ++ NNQ+GFTTD Sbjct: 357 LPGYTTGGTLRVIVNNQVGFTTD 379 >UniRef50_A2QL94 Cluster: Contig An06c0020, complete genome; n=2; Aspergillus|Rep: Contig An06c0020, complete genome - Aspergillus niger Length = 456 Score = 67.7 bits (158), Expect = 2e-10 Identities = 39/84 (46%), Positives = 54/84 (64%), Gaps = 1/84 (1%) Frame = +3 Query: 6 GDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYR-GDNEGKKV 182 GDVKYH G R+ + + + + + PS++E+V+PVV GKTRA Q R GD E K Sbjct: 44 GDVKYHYGGSGARVTP-SGRKVYMNMAPQPSNVESVNPVVMGKTRAIQDRRNGDRE--KT 100 Query: 183 MSILLHGDAAFAGQGVVFETMHLS 254 M + +H DAAFAGQ V+ET+ L+ Sbjct: 101 MMLNVHTDAAFAGQKTVYETLGLA 124 >UniRef50_Q675U8 Cluster: CG1544-PA-like protein; n=1; Oikopleura dioica|Rep: CG1544-PA-like protein - Oikopleura dioica (Tunicate) Length = 886 Score = 60.9 bits (141), Expect = 3e-08 Identities = 27/85 (31%), Positives = 47/85 (55%) Frame = +2 Query: 254 DLPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVC 433 ++P Y G++H +NQ+ FT SRS A D A +P+ V+ +P+ V+ Sbjct: 323 NIPGYDVGGSLHFCCDNQVAFTASGNLSRSCARPGDCALPYGSPVISVSASHPDQVIAAA 382 Query: 434 NVAAEWRATFHKDVVIDIVSYRRNG 508 +A +R F KDV+ ++V +R++G Sbjct: 383 KLALRFRNKFGKDVMTELVGWRKHG 407 Score = 47.2 bits (107), Expect = 3e-04 Identities = 25/82 (30%), Positives = 44/82 (53%) Frame = +3 Query: 6 GDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKVM 185 GDV HL +++ + + +++ NPSHL+A++P GK R++ + G K + Sbjct: 250 GDVLSHL-----QISSTLDSGVSVSLLPNPSHLDAINPAAMGKARSKM-----DHGGKAL 299 Query: 186 SILLHGDAAFAGQGVVFETMHL 251 I HGD + GQG E +++ Sbjct: 300 CIQCHGDGSLIGQGHNHEILNM 321 >UniRef50_Q9RYC1 Cluster: 2-oxo acid dehydrogenase, E1 component, alpha subunit; n=2; Deinococcus|Rep: 2-oxo acid dehydrogenase, E1 component, alpha subunit - Deinococcus radiodurans Length = 381 Score = 46.8 bits (106), Expect = 5e-04 Identities = 23/72 (31%), Positives = 39/72 (54%) Frame = +2 Query: 284 IHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCNVAAEWRATF 463 + + NNQ +T RH +S A+ P F+V+G++ AVM VC+ AAEW Sbjct: 205 LFVCENNQWAISTHIRHQTASENIHIKAKAYGMPGFYVDGNDVVAVMEVCHHAAEWVRAG 264 Query: 464 HKDVVIDIVSYR 499 + +++ ++YR Sbjct: 265 NGPALVECLTYR 276 >UniRef50_Q50992 Cluster: SucA protein; n=3; Neisseria|Rep: SucA protein - Neisseria gonorrhoeae Length = 582 Score = 41.9 bits (94), Expect = 0.013 Identities = 19/42 (45%), Positives = 27/42 (64%) Frame = +1 Query: 508 NNEVDEPMFTQPLMYQKIRKTKPVLEKYADQLIAEGVVTAEE 633 +NE D+P TQP+MY+K+ + Y +QLIAE +VT E Sbjct: 102 HNEGDDPTLTQPMMYKKVSQHPGARALYTEQLIAERLVTQVE 143 >UniRef50_Q835M4 Cluster: Pyruvate dehydrogenase complex E1 component, alpha subunit; n=10; Bacilli|Rep: Pyruvate dehydrogenase complex E1 component, alpha subunit - Enterococcus faecalis (Streptococcus faecalis) Length = 371 Score = 37.5 bits (83), Expect = 0.28 Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 1/87 (1%) Frame = +2 Query: 263 AYTTHGTIHIVANNQIGFTTDPRHSRSSA-YCTDVARVVNAPIFHVNGDNPEAVMHVCNV 439 AY +G + I+ NN +T PR +++A A P V+G +P AV + Sbjct: 193 AYQANG-VFIIQNNGFAIST-PREKQTAAKTLAQKAVAAGIPGIQVDGMDPLAVYAIAKE 250 Query: 440 AAEWRATFHKDVVIDIVSYRRNGTTKS 520 A +W A + V+I+ ++YR T S Sbjct: 251 ARDWSAAGNGPVLIETLTYRYGPHTLS 277 >UniRef50_Q9KJ66 Cluster: Irb5; n=1; Vibrio cholerae|Rep: Irb5 - Vibrio cholerae Length = 53 Score = 37.5 bits (83), Expect = 0.28 Identities = 16/27 (59%), Positives = 19/27 (70%) Frame = +3 Query: 69 IRLAVCANPSHLEAVDPVVQGKTRAEQ 149 + LA+ NPSHLE V+PVV G RA Q Sbjct: 1 VHLALAFNPSHLEIVNPVVMGSVRARQ 27 >UniRef50_Q24678 Cluster: Nucleic acid binding protein; n=1; Girardia tigrina|Rep: Nucleic acid binding protein - Dugesia tigrina (Planarian) Length = 186 Score = 37.5 bits (83), Expect = 0.28 Identities = 23/88 (26%), Positives = 44/88 (50%) Frame = +1 Query: 253 RPARLHHARDHTHRRQQPDRVHDRPQALQIFRLLHRRGPRCKRSDIPRERRQSRGRDARL 432 R ++ HH + HRR+Q R+H++ ++ R+ H PR ++ PR+ R+ + + Sbjct: 18 RYSKTHHVKGKRHRRKQIGRIHNKQRS---HRIRHIHLPRQRKIYQPRKSRRHYQKQRKH 74 Query: 433 *RGCRMESHVPQGRCH*HRQLQEKRNNE 516 R HV +G+ H +Q+ N + Sbjct: 75 RRRYSKTHHV-KGKRHRRKQIGRIHNRQ 101 >UniRef50_A0DHF2 Cluster: Chromosome undetermined scaffold_50, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_50, whole genome shotgun sequence - Paramecium tetraurelia Length = 536 Score = 36.7 bits (81), Expect = 0.48 Identities = 17/53 (32%), Positives = 32/53 (60%), Gaps = 1/53 (1%) Frame = +1 Query: 484 HRQLQEKRNNEVDEPMFTQ-PLMYQKIRKTKPVLEKYADQLIAEGVVTAEEVK 639 + + EKR+NE+ +FTQ P+ Q ++K + L YA+++ E ++ E+K Sbjct: 468 YAERSEKRDNEIQAYIFTQCPMFKQDLKKEQNQLFNYAEKITKEEILNDPEIK 520 >UniRef50_Q5KBR1 Cluster: Putative uncharacterized protein; n=1; Filobasidiella neoformans|Rep: Putative uncharacterized protein - Cryptococcus neoformans (Filobasidiella neoformans) Length = 377 Score = 35.9 bits (79), Expect = 0.84 Identities = 26/56 (46%), Positives = 28/56 (50%) Frame = +1 Query: 256 PARLHHARDHTHRRQQPDRVHDRPQALQIFRLLHRRGPRCKRSDIPRERRQSRGRD 423 P HHA H R QP R H RP L R L GPR + S PR R +SR RD Sbjct: 48 PRSPHHAAGHAAR--QPARPHTRPAFL---RHLTDDGPRSQAS-TPRGRSESRERD 97 >UniRef50_A7SMY1 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 125 Score = 35.5 bits (78), Expect = 1.1 Identities = 14/47 (29%), Positives = 25/47 (53%) Frame = +2 Query: 257 LPAYTTHGTIHIVANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHV 397 +P +T+H + A ++ + PRH + AY ++ RV+ P HV Sbjct: 2 IPTHTSHNDTGLHARDKTSYIIHPRHVTTRAYTHEIKRVIYPPTRHV 48 >UniRef50_Q3JSC1 Cluster: Putative uncharacterized protein; n=4; Burkholderia pseudomallei|Rep: Putative uncharacterized protein - Burkholderia pseudomallei (strain 1710b) Length = 683 Score = 35.1 bits (77), Expect = 1.5 Identities = 25/58 (43%), Positives = 30/58 (51%) Frame = +1 Query: 274 ARDHTHRRQQPDRVHDRPQALQIFRLLHRRGPRCKRSDIPRERRQSRGRDARL*RGCR 447 AR+ HRR + RV A FR L RRG R + D P RR++ R AR RG R Sbjct: 75 ARERRHRRGRRRRVRAAEPARHAFRDLGRRGGRHRDGDQPAARRRA-DRGARR-RGAR 130 >UniRef50_A3Z1Y0 Cluster: Serine protease, subtilase family protein; n=1; Synechococcus sp. WH 5701|Rep: Serine protease, subtilase family protein - Synechococcus sp. WH 5701 Length = 692 Score = 35.1 bits (77), Expect = 1.5 Identities = 20/66 (30%), Positives = 36/66 (54%), Gaps = 1/66 (1%) Frame = -2 Query: 197 QQDRHHLLALVVSPVELLGSGLALHHGVDGLQVRGVRANSQSNVLVGNAIQTLDVR-AQV 21 Q DR+ + L + VE L + L+ H+G+ V + +NS+ L+ +I T+ R AQ+ Sbjct: 404 QLDRYVAVNLTRAEVETLAASLSQHYGIASPAVYRMFSNSKKKALISESIHTVQARTAQL 463 Query: 20 IFHVAG 3 ++ G Sbjct: 464 GYNAYG 469 >UniRef50_Q7RDV5 Cluster: PWI domain, putative; n=3; Plasmodium (Vinckeia)|Rep: PWI domain, putative - Plasmodium yoelii yoelii Length = 438 Score = 34.7 bits (76), Expect = 1.9 Identities = 17/52 (32%), Positives = 29/52 (55%), Gaps = 2/52 (3%) Frame = +1 Query: 271 HARDHTHRRQQPDRVHDRPQALQIFRLLHRR--GPRCKRSDIPRERRQSRGR 420 H RDH R+++ R ++R + + +R+ HR RC+ D R+R + R R Sbjct: 293 HRRDHIVRKRKDRRENERKRDSERYRIRHRTRDRSRCRSRDKSRDRSRDRNR 344 >UniRef50_Q96BV0 Cluster: Zinc finger protein 775; n=3; Homo/Pan/Gorilla group|Rep: Zinc finger protein 775 - Homo sapiens (Human) Length = 537 Score = 34.7 bits (76), Expect = 1.9 Identities = 26/90 (28%), Positives = 39/90 (43%), Gaps = 6/90 (6%) Frame = +1 Query: 223 RASCSRRCTCRPARLHHARDHTHRRQQPDRVHDRPQALQIFRLLHRRGPRCKRSDIPRER 402 R C C R ++ H H +P H P+ + FR H+ G R + R+R Sbjct: 161 RPFCCPECARRFSQKQHLLKHQKTHSRP-ATHSCPECERCFR--HQVGLRIHQRAHARDR 217 Query: 403 RQSRG------RDARL*RGCRMESHVPQGR 474 + SR +DA R CR++ P+GR Sbjct: 218 QGSRAGLHELIQDAAARRACRLQPGPPRGR 247 >UniRef50_UPI0000F1FF18 Cluster: PREDICTED: hypothetical protein; n=1; Danio rerio|Rep: PREDICTED: hypothetical protein - Danio rerio Length = 1614 Score = 34.3 bits (75), Expect = 2.6 Identities = 27/95 (28%), Positives = 44/95 (46%), Gaps = 3/95 (3%) Frame = +2 Query: 323 DPRHSRSSAYCTDVARVVNAPIFH---VNGDNPEAVMHVCNVAAEWRATFHKDVVIDIVS 493 + R YC ++ N+ H +G + V HVCN A + RAT K+ + V Sbjct: 1402 EARRKHQCYYCGELMLTANSLRRHCRQTHGKDRCHVCHVCNKAFK-RATHLKEH--EYV- 1457 Query: 494 YRRNGTTKSTNRCSLSPSCTRRFVRPNQYWRNTRT 598 +++ S R P+C + F +P+Q R+ RT Sbjct: 1458 HKKGPKVNSKPRMFKCPNCDKAFAKPSQLERHNRT 1492 >UniRef50_Q11BT2 Cluster: Putative uncharacterized protein; n=1; Mesorhizobium sp. BNC1|Rep: Putative uncharacterized protein - Mesorhizobium sp. (strain BNC1) Length = 91 Score = 34.3 bits (75), Expect = 2.6 Identities = 16/39 (41%), Positives = 21/39 (53%) Frame = +1 Query: 226 ASCSRRCTCRPARLHHARDHTHRRQQPDRVHDRPQALQI 342 A S RC+C+ RL +R HRR D +H R LQ+ Sbjct: 6 AMLSPRCSCQNRRLKKSRHRHHRRSIGDTLHARSVVLQV 44 >UniRef50_Q0JN66 Cluster: Os01g0323600 protein; n=1; Oryza sativa (japonica cultivar-group)|Rep: Os01g0323600 protein - Oryza sativa subsp. japonica (Rice) Length = 212 Score = 34.3 bits (75), Expect = 2.6 Identities = 36/104 (34%), Positives = 42/104 (40%), Gaps = 6/104 (5%) Frame = +1 Query: 238 RRCTCRPARLHHARDHTHRRQQPDRV-HDRPQALQIFRLLHRRGPRCKRSDIPRE----- 399 RR RP H H RQ P R H PQ L R HRR PR +R P++ Sbjct: 29 RRDRRRPQGARHQAGHP--RQVPRREDHLPPQPLGPLR--HRRAPRRRRPHRPQDHHRHL 84 Query: 400 RRQSRGRDARL*RGCRMESHVPQGRCH*HRQLQEKRNNEVDEPM 531 RR R R RL R + P+ R H QE R P+ Sbjct: 85 RRMGRARRRRLLRQGPDQGR-PERRLHRQAGRQEHRRQRPRPPL 127 >UniRef50_A4HMC2 Cluster: Putative uncharacterized protein; n=3; Leishmania|Rep: Putative uncharacterized protein - Leishmania braziliensis Length = 1982 Score = 34.3 bits (75), Expect = 2.6 Identities = 21/53 (39%), Positives = 27/53 (50%) Frame = +1 Query: 262 RLHHARDHTHRRQQPDRVHDRPQALQIFRLLHRRGPRCKRSDIPRERRQSRGR 420 R HH D + R+QQ R +PQ + RR R KR R+RR+ RGR Sbjct: 759 RHHHRHDGSPRQQQKQRRRLQPQGCR-----QRRSHREKRRKSARQRRRKRGR 806 >UniRef50_UPI0000D578E3 Cluster: PREDICTED: similar to Hypothetical 115 kDa protein in type I retrotransposable element R1DM (ORF 2); n=2; Tribolium castaneum|Rep: PREDICTED: similar to Hypothetical 115 kDa protein in type I retrotransposable element R1DM (ORF 2) - Tribolium castaneum Length = 1208 Score = 33.9 bits (74), Expect = 3.4 Identities = 34/118 (28%), Positives = 48/118 (40%), Gaps = 1/118 (0%) Frame = +2 Query: 293 VANNQIGFTTDPRHSRSSAYCTDVARVVNAPIFHVNGDNPEAVMHVCNV-AAEWRATFHK 469 VANN G+TT S S N P H N ++ ++ A+ F+K Sbjct: 162 VANNIQGWTTMDTESLSDHKIISFKWETNLPDSHQYNSNQPPAWNLKSLNKAKLLKRFNK 221 Query: 470 DVVIDIVSYRRNGTTKSTNRCSLSPSCTRRFVRPNQYWRNTRTS*SRKESSQLRRLKT 643 I+ ++ KS N L S + + R YW N R + RKES + RR T Sbjct: 222 CGSINSPEQLKDSLEKSCNAAMLKKSFSPK--RRPCYWWNDRIAQLRKESIKARRAVT 277 >UniRef50_A1GDX9 Cluster: Peptidyl-prolyl cis-trans isomerase; n=1; Salinispora arenicola CNS205|Rep: Peptidyl-prolyl cis-trans isomerase - Salinispora arenicola CNS205 Length = 375 Score = 33.9 bits (74), Expect = 3.4 Identities = 22/65 (33%), Positives = 25/65 (38%) Frame = +1 Query: 238 RRCTCRPARLHHARDHTHRRQQPDRVHDRPQALQIFRLLHRRGPRCKRSDIPRERRQSRG 417 RR R AR R H PD VHD P RG + + P Q RG Sbjct: 18 RRIRWRAARPRRGRGHVPESPPPDLVHDNPSHWPYTLAGVWRGTPARPTGGPPVTEQGRG 77 Query: 418 RDARL 432 R AR+ Sbjct: 78 RGARV 82 >UniRef50_Q7S6B5 Cluster: Putative uncharacterized protein NCU07137.1; n=1; Neurospora crassa|Rep: Putative uncharacterized protein NCU07137.1 - Neurospora crassa Length = 300 Score = 33.9 bits (74), Expect = 3.4 Identities = 17/34 (50%), Positives = 19/34 (55%) Frame = +1 Query: 238 RRCTCRPARLHHARDHTHRRQQPDRVHDRPQALQ 339 RR CRPAR H DHT RR Q R +P +Q Sbjct: 69 RRARCRPARKAH--DHTARRHQEQRPASKPVDIQ 100 >UniRef50_Q2GW32 Cluster: Putative uncharacterized protein; n=1; Chaetomium globosum|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 888 Score = 33.9 bits (74), Expect = 3.4 Identities = 24/63 (38%), Positives = 32/63 (50%) Frame = +1 Query: 241 RCTCRPARLHHARDHTHRRQQPDRVHDRPQALQIFRLLHRRGPRCKRSDIPRERRQSRGR 420 R T R R RD + ++ DR RP+A + R R PR R+D R+R +SR R Sbjct: 521 RATRRDDRKDDRRDE-RKSERKDRSGSRPRAEK--RERSRSRPRTARTDDKRDRSRSRRR 577 Query: 421 DAR 429 D R Sbjct: 578 DPR 580 >UniRef50_Q0CBK4 Cluster: Putative uncharacterized protein; n=1; Aspergillus terreus NIH2624|Rep: Putative uncharacterized protein - Aspergillus terreus (strain NIH 2624) Length = 227 Score = 33.9 bits (74), Expect = 3.4 Identities = 23/64 (35%), Positives = 29/64 (45%), Gaps = 2/64 (3%) Frame = +1 Query: 256 PARLHHARDHTHRRQQPDRVHDRPQALQIFRLLHRRGPRCKRSDIPRERRQSRGR--DAR 429 P R H R R++ H + ++ R RGPR RS + R R Q RGR R Sbjct: 98 PERTQHRRQRQRHRERWRPHHLGQRQRRLRRRQDERGPRPGRSRLQRRRPQRRGRCESGR 157 Query: 430 L*RG 441 L RG Sbjct: 158 LRRG 161 >UniRef50_Q4PHA6 Cluster: Mediator of RNA polymerase II transcription subunit 6; n=1; Ustilago maydis|Rep: Mediator of RNA polymerase II transcription subunit 6 - Ustilago maydis (Smut fungus) Length = 254 Score = 33.9 bits (74), Expect = 3.4 Identities = 15/39 (38%), Positives = 20/39 (51%), Gaps = 1/39 (2%) Frame = +1 Query: 220 VRASCSRRCTCRPARLHHARDHTHR-RQQPDRVHDRPQA 333 + A +R CT + HHA DHT + Q D +H P A Sbjct: 203 IDADSNRTCTTQSTHTHHADDHTPQLEHQQDHIHPPPPA 241 >UniRef50_Q8TA29 Cluster: Putative pyruvate dehydrogenase; n=1; Heterodera glycines|Rep: Putative pyruvate dehydrogenase - Heterodera glycines (Soybean cyst nematode worm) Length = 132 Score = 33.5 bits (73), Expect = 4.5 Identities = 11/31 (35%), Positives = 23/31 (74%) Frame = +1 Query: 553 QKIRKTKPVLEKYADQLIAEGVVTAEEVKDV 645 Q++RK++ + + D+++ G+VT EE+KD+ Sbjct: 6 QEVRKSRDPITSFKDRIVTAGLVTEEELKDI 36 >UniRef50_Q19854 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 672 Score = 33.5 bits (73), Expect = 4.5 Identities = 22/67 (32%), Positives = 31/67 (46%) Frame = +1 Query: 223 RASCSRRCTCRPARLHHARDHTHRRQQPDRVHDRPQALQIFRLLHRRGPRCKRSDIPRER 402 R S SRR + R +R RR PDR +R ++ R HR +R ++R Sbjct: 430 RRSNSRRRSRSRDRQRRSRSRDRRRYSPDR-RERRRSRSRDRRRHRSRSTSRRRQRSKDR 488 Query: 403 RQSRGRD 423 R+ R RD Sbjct: 489 RRDRSRD 495 >UniRef50_Q3JV89 Cluster: Putative uncharacterized protein; n=6; Burkholderia|Rep: Putative uncharacterized protein - Burkholderia pseudomallei (strain 1710b) Length = 683 Score = 33.1 bits (72), Expect = 5.9 Identities = 16/34 (47%), Positives = 20/34 (58%) Frame = +1 Query: 220 VRASCSRRCTCRPARLHHARDHTHRRQQPDRVHD 321 V +SCS R T PAR H +R T R++P R D Sbjct: 598 VASSCSARQTRLPARRHTSRSSTRMRRRPARSRD 631 >UniRef50_A0JY86 Cluster: Putative uncharacterized protein; n=2; Arthrobacter|Rep: Putative uncharacterized protein - Arthrobacter sp. (strain FB24) Length = 290 Score = 33.1 bits (72), Expect = 5.9 Identities = 22/57 (38%), Positives = 27/57 (47%) Frame = -2 Query: 173 ALVVSPVELLGSGLALHHGVDGLQVRGVRANSQSNVLVGNAIQTLDVRAQVIFHVAG 3 AL S G G LHH +DG VR + L GNA+ T D A +F V+G Sbjct: 203 ALCASAANRRGWGDGLHHVLDGTTGAPVRTVVATWALAGNAM-TADALATALFFVSG 258 >UniRef50_Q62KZ5 Cluster: Putative uncharacterized protein; n=5; Burkholderia mallei|Rep: Putative uncharacterized protein - Burkholderia mallei (Pseudomonas mallei) Length = 154 Score = 32.7 bits (71), Expect = 7.8 Identities = 23/50 (46%), Positives = 25/50 (50%), Gaps = 4/50 (8%) Frame = +1 Query: 283 HTHRRQ--QPDRVHDRPQALQIFRLLHRR--GPRCKRSDIPRERRQSRGR 420 H HRR+ QP RV D P A Q HRR G R + D R R RGR Sbjct: 32 HRHRRRARQPRRVRDEPHATQ---RRHRRGGGRRARLPDHGRADRHGRGR 78 >UniRef50_Q5H6J7 Cluster: Xylose repressor-like protein; n=6; Xanthomonas|Rep: Xylose repressor-like protein - Xanthomonas oryzae pv. oryzae Length = 394 Score = 32.7 bits (71), Expect = 7.8 Identities = 16/49 (32%), Positives = 27/49 (55%) Frame = +1 Query: 250 CRPARLHHARDHTHRRQQPDRVHDRPQALQIFRLLHRRGPRCKRSDIPR 396 C P+ +A +H R++ D P+ + L+ R G +C+RSD+PR Sbjct: 9 CMPSLFANAAIRSHYRRRSDGQAAAPRERLLLDLIRRAG-QCERSDLPR 56 >UniRef50_Q1YEG0 Cluster: Putative uncharacterized protein; n=1; Aurantimonas sp. SI85-9A1|Rep: Putative uncharacterized protein - Aurantimonas sp. SI85-9A1 Length = 130 Score = 32.7 bits (71), Expect = 7.8 Identities = 18/38 (47%), Positives = 23/38 (60%) Frame = -2 Query: 362 RLCSRRKIWSAWGRS*TRSGCWRRCVWSRAWCRRAGRQ 249 R C R+ +A+GRS +R G RR WS A R AGR+ Sbjct: 94 RWCRCRRA-AAYGRSASRRGSVRRTTWSAASARPAGRR 130 >UniRef50_Q9C8M7 Cluster: Peptidyl-prolyl cis-trans isomerase; n=10; Magnoliophyta|Rep: Peptidyl-prolyl cis-trans isomerase - Arabidopsis thaliana (Mouse-ear cress) Length = 509 Score = 32.7 bits (71), Expect = 7.8 Identities = 25/82 (30%), Positives = 33/82 (40%) Frame = +1 Query: 277 RDHTHRRQQPDRVHDRPQALQIFRLLHRRGPRCKRSDIPRERRQSRGRDARL*RGCRMES 456 R H R R HDR A ++ R R R R D +RR+ R R+ + R E Sbjct: 419 RQHRDERDDGRRQHDREDARELERKHRERKERESRED--EDRRRRRRREESRDKESRRER 476 Query: 457 HVPQGRCH*HRQLQEKRNNEVD 522 R HR +E+R D Sbjct: 477 DEDDHRS--HRDYKERRRERDD 496 >UniRef50_Q69XY6 Cluster: Putative uncharacterized protein P0633D04.18; n=1; Oryza sativa (japonica cultivar-group)|Rep: Putative uncharacterized protein P0633D04.18 - Oryza sativa subsp. japonica (Rice) Length = 140 Score = 32.7 bits (71), Expect = 7.8 Identities = 16/47 (34%), Positives = 23/47 (48%) Frame = -2 Query: 362 RLCSRRKIWSAWGRS*TRSGCWRRCVWSRAWCRRAGRQVHRLEHDAL 222 R C R +A TR CWR + WCRR ++ HR++ D + Sbjct: 56 RPCWRADGGAALANKGTRRPCWRAV--AGGWCRRHRQRCHRMQEDTV 100 >UniRef50_Q01D15 Cluster: Chromosome 03 contig 1, DNA sequence; n=1; Ostreococcus tauri|Rep: Chromosome 03 contig 1, DNA sequence - Ostreococcus tauri Length = 213 Score = 32.7 bits (71), Expect = 7.8 Identities = 20/48 (41%), Positives = 29/48 (60%), Gaps = 1/48 (2%) Frame = +1 Query: 274 ARDHTHRR-QQPDRVHDRPQALQIFRLLHRRGPRCKRSDIPRERRQSR 414 AR + RR + P R+ DRP+A+ ++ RR PR +R +PR R SR Sbjct: 128 ARPSSGRRPRHPPRI-DRPRAVVTVVVVRRR-PRARRRAVPRHSRHSR 173 >UniRef50_A7S8G5 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 686 Score = 32.7 bits (71), Expect = 7.8 Identities = 17/35 (48%), Positives = 22/35 (62%), Gaps = 2/35 (5%) Frame = +1 Query: 367 PRCKRSDIP--RERRQSRGRDARL*RGCRMESHVP 465 PR +RS + RERR SR + RL +G +ESH P Sbjct: 628 PRAQRSSVSSLRERRASRETEKRLSKGSSIESHEP 662 >UniRef50_Q05738 Cluster: Sex-determining region Y protein; n=35; Muroidea|Rep: Sex-determining region Y protein - Mus musculus (Mouse) Length = 395 Score = 32.7 bits (71), Expect = 7.8 Identities = 23/95 (24%), Positives = 40/95 (42%) Frame = +1 Query: 268 HHARDHTHRRQQPDRVHDRPQALQIFRLLHRRGPRCKRSDIPRERRQSRGRDARL*RGCR 447 H DH ++QQ HD PQ Q F H + + K+ +++ + D + Sbjct: 279 HQFHDHPQQKQQ---FHDHPQQQQQFHDHHHQQQQ-KQQFHDHHQQKQQFHDHHQQKQQF 334 Query: 448 MESHVPQGRCH*HRQLQEKRNNEVDEPMFTQPLMY 552 + H Q + H H Q Q+++ + + Q L Y Sbjct: 335 HDHHQQQQQFHDHHQQQQQQQQQQQQQFHDQQLTY 369 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 653,656,739 Number of Sequences: 1657284 Number of extensions: 13493905 Number of successful extensions: 46250 Number of sequences better than 10.0: 111 Number of HSP's better than 10.0 without gapping: 43597 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 46064 length of database: 575,637,011 effective HSP length: 98 effective length of database: 413,223,179 effective search space used: 48760335122 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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