Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= NV021370
(513 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000D55EDD Cluster: PREDICTED: similar to CG11822-PA... 40 0.033
UniRef50_Q19351 Cluster: Ligand-gated ion channel protein 3; n=3... 39 0.077
UniRef50_Q67X94 Cluster: Putative uncharacterized protein lgc-2;... 38 0.18
UniRef50_A0EIZ9 Cluster: Nicotinic acetylcholine receptor beta2 ... 34 2.2
UniRef50_Q4DQP8 Cluster: Protein kinase-like protein, putative; ... 33 2.9
UniRef50_Q22085 Cluster: Putative uncharacterized protein lgc-17... 33 2.9
UniRef50_Q0GQR6 Cluster: GABA-gated ion channel; n=2; Apis melli... 33 3.8
UniRef50_O16926 Cluster: Acetylcholine receptor protein 15; n=2;... 33 3.8
UniRef50_Q23022 Cluster: Acetylcholine receptor subunit alpha-ty... 33 3.8
UniRef50_UPI0000D9B95E Cluster: PREDICTED: hypothetical protein;... 33 5.0
UniRef50_Q4R170 Cluster: Putative uncharacterized protein; n=1; ... 33 5.0
UniRef50_Q14DU4 Cluster: CHRNG protein; n=3; Euarchontoglires|Re... 33 5.0
UniRef50_P07510 Cluster: Acetylcholine receptor subunit gamma pr... 33 5.0
UniRef50_UPI00015B5C4C Cluster: PREDICTED: similar to GABA-gated... 32 6.7
UniRef50_Q9GUF0 Cluster: Ligand-gated ion channel protein 10; n=... 32 6.7
UniRef50_Q66T21 Cluster: Nicotinic acetylcholine receptor subuni... 32 6.7
UniRef50_Q2XWK6 Cluster: Nicotinic acetylcholine receptor subuni... 32 6.7
UniRef50_P34271 Cluster: Acetylcholine receptor-like protein cup... 32 6.7
UniRef50_Q9VAP9 Cluster: CG11873-PA; n=1; Drosophila melanogaste... 32 8.8
UniRef50_O16426 Cluster: Ligand-gated ion channel protein 1; n=2... 32 8.8
UniRef50_A7UFK6 Cluster: Nicotinic acetylcholine receptor alpha ... 32 8.8
>UniRef50_UPI0000D55EDD Cluster: PREDICTED: similar to CG11822-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG11822-PA, isoform A - Tribolium castaneum
Length = 438
Score = 39.9 bits (89), Expect = 0.033
Identities = 21/70 (30%), Positives = 40/70 (57%), Gaps = 5/70 (7%)
Frame = +2
Query: 59 NATSLSLMIDSLLATYDRESPP-----DSKIVVNLTLHLRHANIREXESTVRILADLQMN 223
N+T + LL YD+ + P +K+V LT+ RH + E +ST+ + + ++++
Sbjct: 36 NSTVTDKLRQDLLLNYDKFARPAQHYNTTKVVFGLTI--RHIELNEFKSTLVVHSWIRLS 93
Query: 224 WIDKRLSWNA 253
W D++L WN+
Sbjct: 94 WKDEKLQWNS 103
>UniRef50_Q19351 Cluster: Ligand-gated ion channel protein 3; n=3;
Caenorhabditis|Rep: Ligand-gated ion channel protein 3 -
Caenorhabditis elegans
Length = 355
Score = 38.7 bits (86), Expect = 0.077
Identities = 23/86 (26%), Positives = 42/86 (48%), Gaps = 3/86 (3%)
Frame = +2
Query: 23 LTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRHA-NIREXESTVR 199
+T +A +E +S S + LL +++ SPPD ++ ++ + L H I E ++
Sbjct: 55 VTVGVAEFSEQYQGSS-SRLTRHLLEKHNKCSPPDGRVDISHNIELVHIIGINELNQNMQ 113
Query: 200 ILADLQMNWIDKRLSWNAG--XGLQH 271
+L + W D LSW G++H
Sbjct: 114 VLVYIVQQWTDASLSWKVEEFRGIKH 139
>UniRef50_Q67X94 Cluster: Putative uncharacterized protein lgc-2;
n=3; Caenorhabditis|Rep: Putative uncharacterized
protein lgc-2 - Caenorhabditis elegans
Length = 509
Score = 37.5 bits (83), Expect = 0.18
Identities = 17/58 (29%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
Frame = +2
Query: 80 MIDSLLATYDRESPPDSKIVVNLTLHLRHA-NIREXESTVRILADLQMNWIDKRLSWN 250
+ + LL+ ++ +PPD + V L L H I E + T+ +L + +W+D L+W+
Sbjct: 70 LTEYLLSRHNLNAPPDGLLYVEYELELVHILGIDELKQTMTVLIYVDEHWVDPSLTWD 127
>UniRef50_A0EIZ9 Cluster: Nicotinic acetylcholine receptor beta2
subunit; n=1; Apis mellifera|Rep: Nicotinic
acetylcholine receptor beta2 subunit - Apis mellifera
(Honeybee)
Length = 427
Score = 33.9 bits (74), Expect = 2.2
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 5/72 (6%)
Frame = +2
Query: 53 CENATSLSLMIDS---LLATYDRESPPDSKIV--VNLTLHLRHANIREXESTVRILADLQ 217
C++ TS S + L YDR+ P+ K ++ L ++H N+ E TV L+
Sbjct: 28 CKDITSTSALYRLKLYLFCDYDRDIIPEQKNATKIDFGLSIQHYNVDEYSHTVDFHVMLK 87
Query: 218 MNWIDKRLSWNA 253
+ W L+W +
Sbjct: 88 LMWEQSHLTWKS 99
>UniRef50_Q4DQP8 Cluster: Protein kinase-like protein, putative;
n=2; Trypanosoma cruzi|Rep: Protein kinase-like protein,
putative - Trypanosoma cruzi
Length = 1758
Score = 33.5 bits (73), Expect = 2.9
Identities = 17/49 (34%), Positives = 24/49 (48%)
Frame = -1
Query: 150 VRLTTILESGGDSRSYVARSESIMRDSDVAFSHSAALAIAQVRRNGNLV 4
+ L TIL GGD SE+I+ D H+ ++ Q+ R G LV
Sbjct: 365 INLATILVEGGDDAVTEKISENILFDEVTGLPHAPSVGRLQIERTGRLV 413
>UniRef50_Q22085 Cluster: Putative uncharacterized protein lgc-17;
n=12; Caenorhabditis|Rep: Putative uncharacterized
protein lgc-17 - Caenorhabditis elegans
Length = 401
Score = 33.5 bits (73), Expect = 2.9
Identities = 13/36 (36%), Positives = 21/36 (58%)
Frame = +2
Query: 146 LTLHLRHANIREXESTVRILADLQMNWIDKRLSWNA 253
L +L+ ++E E V ++ +L W D RLSWN+
Sbjct: 79 LLYYLKLVEVQEPEEKVSVVLELVEQWYDPRLSWNS 114
>UniRef50_Q0GQR6 Cluster: GABA-gated ion channel; n=2; Apis
mellifera|Rep: GABA-gated ion channel - Apis mellifera
(Honeybee)
Length = 463
Score = 33.1 bits (72), Expect = 3.8
Identities = 19/70 (27%), Positives = 36/70 (51%), Gaps = 4/70 (5%)
Frame = +2
Query: 59 NATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IREXESTVRILADLQMNW 226
N +++S ++D+LL YD PD V + + +R I E + T + + +W
Sbjct: 2 NHSNISELLDNLLRGYDNSVRPDFGGPPATVEVDIMVRSMGPISEVDMTYSMDCYFRQSW 61
Query: 227 IDKRLSWNAG 256
+D+RL++ G
Sbjct: 62 VDRRLAFQGG 71
>UniRef50_O16926 Cluster: Acetylcholine receptor protein 15; n=2;
Caenorhabditis|Rep: Acetylcholine receptor protein 15 -
Caenorhabditis elegans
Length = 479
Score = 33.1 bits (72), Expect = 3.8
Identities = 21/61 (34%), Positives = 34/61 (55%), Gaps = 5/61 (8%)
Frame = +2
Query: 80 MIDSLLATYDRESPP--DSK--IVVNLTLHLRHA-NIREXESTVRILADLQMNWIDKRLS 244
+I+ L++ Y RE P DS +VV+L + L+ N+ E E + + A L+ W D+ L
Sbjct: 25 LINDLMSGYVREERPTLDSSKPVVVSLGVFLQQIINLSEKEEQLEVNAWLKFQWRDENLR 84
Query: 245 W 247
W
Sbjct: 85 W 85
>UniRef50_Q23022 Cluster: Acetylcholine receptor subunit alpha-type
unc-38 precursor; n=9; Chromadorea|Rep: Acetylcholine
receptor subunit alpha-type unc-38 precursor -
Caenorhabditis elegans
Length = 511
Score = 33.1 bits (72), Expect = 3.8
Identities = 20/82 (24%), Positives = 36/82 (43%), Gaps = 5/82 (6%)
Frame = +2
Query: 20 LLTCAIASAAECENATSLSLMIDSLLATYDRE----SPPDSKIVVNLTLHLRHA-NIREX 184
LL I+ E + D L+ Y+R + P+ + + L L L ++ E
Sbjct: 10 LLLFCISFIKLTEGNEDAKRLYDDLMVNYNRHRRPSTSPNKPLTIKLKLRLSQIIDVHEI 69
Query: 185 ESTVRILADLQMNWIDKRLSWN 250
+ + L+ WID++LSW+
Sbjct: 70 DQIMTCSVWLKQTWIDRKLSWD 91
>UniRef50_UPI0000D9B95E Cluster: PREDICTED: hypothetical protein;
n=1; Macaca mulatta|Rep: PREDICTED: hypothetical protein
- Macaca mulatta
Length = 221
Score = 32.7 bits (71), Expect = 5.0
Identities = 31/110 (28%), Positives = 43/110 (39%), Gaps = 1/110 (0%)
Frame = -1
Query: 345 PRRWLQPRLAVPXQASTSVPRTPAKCCSPIPAFQLSRLSIQFI*RSASIRTVDSXSRMLA 166
PR W RLA A+ PR P +P+P L R ++ ++S T S A
Sbjct: 2 PRSWGPYRLA----AAAVFPRLPRGFPAPLPPPLLRRSPVRLTQNNSSRATASSPLHTQA 57
Query: 165 CLKCRVRLTTILE-SGGDSRSYVARSESIMRDSDVAFSHSAALAIAQVRR 19
C+ L SG +RS V S+ + VA +A RR
Sbjct: 58 CVSAGSALRNCSSTSGSRTRSLVCTSDQVQGARRVAQVEAAEAVPRGTRR 107
>UniRef50_Q4R170 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 404
Score = 32.7 bits (71), Expect = 5.0
Identities = 16/54 (29%), Positives = 28/54 (51%), Gaps = 2/54 (3%)
Frame = +2
Query: 119 PPDSKIVVNLTLHLRHANIREXESTVRILADLQMNWIDKRLSWNAG--XGLQHL 274
PP +I + L++ ++ + E E L D + +W D RLSW+ G+ H+
Sbjct: 79 PPRFEITIQLSM-MKLVEVVEPEEKATFLFDYRADWYDTRLSWDPEDYGGINHI 131
>UniRef50_Q14DU4 Cluster: CHRNG protein; n=3; Euarchontoglires|Rep:
CHRNG protein - Homo sapiens (Human)
Length = 465
Score = 32.7 bits (71), Expect = 5.0
Identities = 23/88 (26%), Positives = 37/88 (42%), Gaps = 5/88 (5%)
Frame = +2
Query: 2 GTRLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANI 175
G + P LL +A + ++ L+ YD P + VVN++L L N+
Sbjct: 3 GGQGPLLLLLLLAVCLGAQGRNQEERLLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNL 62
Query: 176 ---REXESTVRILADLQMNWIDKRLSWN 250
E E + ++M W D RL W+
Sbjct: 63 ISLNEREEALTTNVWIEMQWCDYRLRWD 90
>UniRef50_P07510 Cluster: Acetylcholine receptor subunit gamma
precursor; n=31; Gnathostomata|Rep: Acetylcholine
receptor subunit gamma precursor - Homo sapiens (Human)
Length = 517
Score = 32.7 bits (71), Expect = 5.0
Identities = 23/88 (26%), Positives = 37/88 (42%), Gaps = 5/88 (5%)
Frame = +2
Query: 2 GTRLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANI 175
G + P LL +A + ++ L+ YD P + VVN++L L N+
Sbjct: 3 GGQGPLLLLLLLAVCLGAQGRNQEERLLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNL 62
Query: 176 ---REXESTVRILADLQMNWIDKRLSWN 250
E E + ++M W D RL W+
Sbjct: 63 ISLNEREEALTTNVWIEMQWCDYRLRWD 90
>UniRef50_UPI00015B5C4C Cluster: PREDICTED: similar to GABA-gated
ion channel; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to GABA-gated ion channel - Nasonia vitripennis
Length = 442
Score = 32.3 bits (70), Expect = 6.7
Identities = 19/73 (26%), Positives = 38/73 (52%), Gaps = 4/73 (5%)
Frame = +2
Query: 50 ECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IREXESTVRILADLQ 217
+ N ++S ++D+LL YD P+ VV + + +R I E + T + +
Sbjct: 43 QSNNHGNISELLDNLLRGYDNSVRPNFGGPPAVVEVDIMVRSMGPISEVDMTYSMDCYFR 102
Query: 218 MNWIDKRLSWNAG 256
+W+D+RL++ +G
Sbjct: 103 QSWVDRRLAFQSG 115
>UniRef50_Q9GUF0 Cluster: Ligand-gated ion channel protein 10; n=3;
Caenorhabditis|Rep: Ligand-gated ion channel protein 10
- Caenorhabditis elegans
Length = 493
Score = 32.3 bits (70), Expect = 6.7
Identities = 21/76 (27%), Positives = 35/76 (46%), Gaps = 7/76 (9%)
Frame = +2
Query: 44 AAECENATSL----SLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA-NIREXESTVRI 202
A CEN +L S +++ + YDR P ++VN+T+ L ++E +
Sbjct: 57 ALNCENFRTLDNETSAILNDIFVGYDRRVLPFVQGPVLVNMTIVLGILIELKENQQLAAY 116
Query: 203 LADLQMNWIDKRLSWN 250
+ W D RLSW+
Sbjct: 117 VISHTQRWYDGRLSWD 132
>UniRef50_Q66T21 Cluster: Nicotinic acetylcholine receptor subunit
alpha 9; n=4; Culicidae|Rep: Nicotinic acetylcholine
receptor subunit alpha 9 - Anopheles gambiae (African
malaria mosquito)
Length = 406
Score = 32.3 bits (70), Expect = 6.7
Identities = 17/56 (30%), Positives = 28/56 (50%), Gaps = 3/56 (5%)
Frame = +2
Query: 92 LLATYD---RESPPDSKIVVNLTLHLRHANIREXESTVRILADLQMNWIDKRLSWN 250
LL YD R S + V + + H I E +ST+ + ++ +W D +L+WN
Sbjct: 46 LLKGYDPSIRPSQHYNVTTVETGITITHVEINEIKSTLSVYGWMKFSWNDPKLTWN 101
>UniRef50_Q2XWK6 Cluster: Nicotinic acetylcholine receptor subunit
type G; n=1; Lymnaea stagnalis|Rep: Nicotinic
acetylcholine receptor subunit type G - Lymnaea
stagnalis (Great pond snail)
Length = 618
Score = 32.3 bits (70), Expect = 6.7
Identities = 18/63 (28%), Positives = 34/63 (53%), Gaps = 5/63 (7%)
Frame = +2
Query: 77 LMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIREXESTVRILAD---LQMNWIDKRL 241
L+++ LLA Y R S P ++ + V + L I + + ++L L+ W+D+RL
Sbjct: 90 LLMERLLARYHRYSRPVMNASLSVQVKFGLTLVQISDMDEVNQVLTINVWLEQEWVDERL 149
Query: 242 SWN 250
+W+
Sbjct: 150 TWS 152
>UniRef50_P34271 Cluster: Acetylcholine receptor-like protein cup-4
precursor; n=3; Caenorhabditis|Rep: Acetylcholine
receptor-like protein cup-4 precursor - Caenorhabditis
elegans
Length = 433
Score = 32.3 bits (70), Expect = 6.7
Identities = 11/38 (28%), Positives = 22/38 (57%)
Frame = +2
Query: 137 VVNLTLHLRHANIREXESTVRILADLQMNWIDKRLSWN 250
+V++ H+ H +I + E T+ + + M W D+ L W+
Sbjct: 74 IVDVHWHIIHVSINQREQTMTVHGHIYMRWFDEFLVWD 111
>UniRef50_Q9VAP9 Cluster: CG11873-PA; n=1; Drosophila
melanogaster|Rep: CG11873-PA - Drosophila melanogaster
(Fruit fly)
Length = 2977
Score = 31.9 bits (69), Expect = 8.8
Identities = 23/76 (30%), Positives = 34/76 (44%)
Frame = -1
Query: 333 LQPRLAVPXQASTSVPRTPAKCCSPIPAFQLSRLSIQFI*RSASIRTVDSXSRMLACLKC 154
LQP+L P S+P P SP PA QL+ Q R ++ +D ++ L CL
Sbjct: 1391 LQPQLQ-PVTVPVSLPTQPVPIPSPAPAPQLANNGQQ---RYIALPPIDPTTQQLFCLNS 1446
Query: 153 RVRLTTILESGGDSRS 106
T + +G + S
Sbjct: 1447 VTNQITAMSAGQTAAS 1462
>UniRef50_O16426 Cluster: Ligand-gated ion channel protein 1; n=2;
Caenorhabditis elegans|Rep: Ligand-gated ion channel
protein 1 - Caenorhabditis elegans
Length = 371
Score = 31.9 bits (69), Expect = 8.8
Identities = 14/44 (31%), Positives = 24/44 (54%)
Frame = +2
Query: 119 PPDSKIVVNLTLHLRHANIREXESTVRILADLQMNWIDKRLSWN 250
PP +++ + + + L+ ++ E E V L D W D+RL WN
Sbjct: 51 PPITELKLTMAM-LKLVDVVEVEEKVTFLFDYLAEWTDQRLKWN 93
>UniRef50_A7UFK6 Cluster: Nicotinic acetylcholine receptor alpha
subunit; n=2; Ascaris suum|Rep: Nicotinic acetylcholine
receptor alpha subunit - Ascaris suum (Pig roundworm)
(Ascaris lumbricoides)
Length = 513
Score = 31.9 bits (69), Expect = 8.8
Identities = 22/85 (25%), Positives = 38/85 (44%), Gaps = 5/85 (5%)
Frame = +2
Query: 11 LPFLLTCAIASAAECENATSLSLMIDSLLATYDRES----PPDSKIVVNLTLHLRHA-NI 175
L +L+ C + E+A L D L+ Y++ P + + L L L ++
Sbjct: 8 LLWLVVCGTSLTVGNEDAKRL---YDDLMVNYNKHRRPAMSPHEPVTIKLKLRLSQIIDV 64
Query: 176 REXESTVRILADLQMNWIDKRLSWN 250
E + + L+ WIDK+LSW+
Sbjct: 65 HEIDQIMTYSVWLKQVWIDKKLSWD 89
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 513,593,642
Number of Sequences: 1657284
Number of extensions: 9928469
Number of successful extensions: 27545
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 26633
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 27537
length of database: 575,637,011
effective HSP length: 95
effective length of database: 418,195,031
effective search space used: 31364627325
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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