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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= NV021370
         (513 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC111802-1|AAI11803.1|  465|Homo sapiens CHRNG protein protein.        33   0.77 
Y00762-1|CAA68731.1|  457|Homo sapiens protein ( Human mRNA for ...    30   5.5  
X02502-1|CAA26344.1|  457|Homo sapiens acetylcholine receptor pr...    30   5.5  
S77094-1|AAD14247.1|  457|Homo sapiens nicotinic acetylcholine r...    30   5.5  
BC006314-1|AAH06314.1|  269|Homo sapiens CHRNA1 protein protein.       30   5.5  
AC018890-1|AAY14687.1|  457|Homo sapiens unknown protein.              30   5.5  
S77554-1|AAB33983.1|  474|Homo sapiens GABAA receptor beta 2 sub...    29   7.2  
S77553-1|AAB33982.1|  512|Homo sapiens GABAA receptor beta 2 sub...    29   7.2  
S67368-1|AAB29370.1|  474|Homo sapiens gamma-aminobutyric acid A...    29   7.2  
BC105639-1|AAI05640.1|  474|Homo sapiens GABRB2 protein protein.       29   7.2  
BC099719-1|AAH99719.1|  474|Homo sapiens GABRB2 protein protein.       29   7.2  
BC099705-1|AAH99705.1|  474|Homo sapiens GABRB2 protein protein.       29   7.2  
AK122582-1|BAC56923.1| 1383|Homo sapiens FLJ00269 protein protein.     29   7.2  
X55019-1|CAA38759.1|  517|Homo sapiens acetylcholine receptor de...    29   9.5  
M59216-1|AAA35862.1|  474|Homo sapiens gamma-aminobutyric acid r...    29   9.5  
BC093925-1|AAH93925.1|  517|Homo sapiens cholinergic receptor, n...    29   9.5  
BC093923-1|AAH93923.1|  517|Homo sapiens cholinergic receptor, n...    29   9.5  
BC022449-1|AAH22449.1|  474|Homo sapiens gamma-aminobutyric acid...    29   9.5  
AC092165-2|AAY24102.1|  517|Homo sapiens unknown protein.              29   9.5  

>BC111802-1|AAI11803.1|  465|Homo sapiens CHRNG protein protein.
          Length = 465

 Score = 32.7 bits (71), Expect = 0.77
 Identities = 23/88 (26%), Positives = 37/88 (42%), Gaps = 5/88 (5%)
 Frame = +2

Query: 2   GTRLPFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANI 175
           G + P LL   +A     +       ++  L+  YD    P  +   VVN++L L   N+
Sbjct: 3   GGQGPLLLLLLLAVCLGAQGRNQEERLLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNL 62

Query: 176 ---REXESTVRILADLQMNWIDKRLSWN 250
               E E  +     ++M W D RL W+
Sbjct: 63  ISLNEREEALTTNVWIEMQWCDYRLRWD 90


>Y00762-1|CAA68731.1|  457|Homo sapiens protein ( Human mRNA for
           muscle acetylcholine receptor alpha-subunit. ).
          Length = 457

 Score = 29.9 bits (64), Expect = 5.5
 Identities = 22/84 (26%), Positives = 35/84 (41%), Gaps = 5/84 (5%)
 Frame = +2

Query: 14  PFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIR 178
           P LL  ++ SA     +   + ++  L   Y     P  D + VV +T+ L+     N+ 
Sbjct: 5   PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64

Query: 179 EXESTVRILADLQMNWIDKRLSWN 250
           E    V     L+  W+D  L WN
Sbjct: 65  EVNQIVTTNVRLKQQWVDYNLKWN 88


>X02502-1|CAA26344.1|  457|Homo sapiens acetylcholine receptor
           protein.
          Length = 457

 Score = 29.9 bits (64), Expect = 5.5
 Identities = 22/84 (26%), Positives = 35/84 (41%), Gaps = 5/84 (5%)
 Frame = +2

Query: 14  PFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIR 178
           P LL  ++ SA     +   + ++  L   Y     P  D + VV +T+ L+     N+ 
Sbjct: 5   PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64

Query: 179 EXESTVRILADLQMNWIDKRLSWN 250
           E    V     L+  W+D  L WN
Sbjct: 65  EVNQIVTTNVRLKQQWVDYNLKWN 88


>S77094-1|AAD14247.1|  457|Homo sapiens nicotinic acetylcholine
           receptor alpha subunit|AChR protein.
          Length = 457

 Score = 29.9 bits (64), Expect = 5.5
 Identities = 22/84 (26%), Positives = 35/84 (41%), Gaps = 5/84 (5%)
 Frame = +2

Query: 14  PFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIR 178
           P LL  ++ SA     +   + ++  L   Y     P  D + VV +T+ L+     N+ 
Sbjct: 5   PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64

Query: 179 EXESTVRILADLQMNWIDKRLSWN 250
           E    V     L+  W+D  L WN
Sbjct: 65  EVNQIVTTNVRLKQQWVDYNLKWN 88


>BC006314-1|AAH06314.1|  269|Homo sapiens CHRNA1 protein protein.
          Length = 269

 Score = 29.9 bits (64), Expect = 5.5
 Identities = 22/84 (26%), Positives = 35/84 (41%), Gaps = 5/84 (5%)
 Frame = +2

Query: 14  PFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIR 178
           P LL  ++ SA     +   + ++  L   Y     P  D + VV +T+ L+     N+ 
Sbjct: 5   PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64

Query: 179 EXESTVRILADLQMNWIDKRLSWN 250
           E    V     L+  W+D  L WN
Sbjct: 65  EVNQIVTTNVRLKQQWVDYNLKWN 88


>AC018890-1|AAY14687.1|  457|Homo sapiens unknown protein.
          Length = 457

 Score = 29.9 bits (64), Expect = 5.5
 Identities = 22/84 (26%), Positives = 35/84 (41%), Gaps = 5/84 (5%)
 Frame = +2

Query: 14  PFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIR 178
           P LL  ++ SA     +   + ++  L   Y     P  D + VV +T+ L+     N+ 
Sbjct: 5   PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64

Query: 179 EXESTVRILADLQMNWIDKRLSWN 250
           E    V     L+  W+D  L WN
Sbjct: 65  EVNQIVTTNVRLKQQWVDYNLKWN 88


>S77554-1|AAB33983.1|  474|Homo sapiens GABAA receptor beta 2
           subunit protein.
          Length = 474

 Score = 29.5 bits (63), Expect = 7.2
 Identities = 23/85 (27%), Positives = 37/85 (43%), Gaps = 7/85 (8%)
 Frame = +2

Query: 17  FLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHLRHAN-I 175
           F L  A   A    + +++SL+   +D LL  YD    PD     + V + + +   + +
Sbjct: 15  FPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMV 74

Query: 176 REXESTVRILADLQMNWIDKRLSWN 250
            E      +    Q  W DKRLS+N
Sbjct: 75  SEVNMDYTLTMYFQQAWRDKRLSYN 99


>S77553-1|AAB33982.1|  512|Homo sapiens GABAA receptor beta 2
           subunit protein.
          Length = 512

 Score = 29.5 bits (63), Expect = 7.2
 Identities = 23/85 (27%), Positives = 37/85 (43%), Gaps = 7/85 (8%)
 Frame = +2

Query: 17  FLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHLRHAN-I 175
           F L  A   A    + +++SL+   +D LL  YD    PD     + V + + +   + +
Sbjct: 15  FPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMV 74

Query: 176 REXESTVRILADLQMNWIDKRLSWN 250
            E      +    Q  W DKRLS+N
Sbjct: 75  SEVNMDYTLTMYFQQAWRDKRLSYN 99


>S67368-1|AAB29370.1|  474|Homo sapiens gamma-aminobutyric acid A
           receptor beta 2 subunit protein.
          Length = 474

 Score = 29.5 bits (63), Expect = 7.2
 Identities = 23/85 (27%), Positives = 37/85 (43%), Gaps = 7/85 (8%)
 Frame = +2

Query: 17  FLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHLRHAN-I 175
           F L  A   A    + +++SL+   +D LL  YD    PD     + V + + +   + +
Sbjct: 15  FPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMV 74

Query: 176 REXESTVRILADLQMNWIDKRLSWN 250
            E      +    Q  W DKRLS+N
Sbjct: 75  SEVNMDYTLTMYFQQAWRDKRLSYN 99


>BC105639-1|AAI05640.1|  474|Homo sapiens GABRB2 protein protein.
          Length = 474

 Score = 29.5 bits (63), Expect = 7.2
 Identities = 23/85 (27%), Positives = 37/85 (43%), Gaps = 7/85 (8%)
 Frame = +2

Query: 17  FLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHLRHAN-I 175
           F L  A   A    + +++SL+   +D LL  YD    PD     + V + + +   + +
Sbjct: 15  FPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMV 74

Query: 176 REXESTVRILADLQMNWIDKRLSWN 250
            E      +    Q  W DKRLS+N
Sbjct: 75  SEVNMDYTLTMYFQQAWRDKRLSYN 99


>BC099719-1|AAH99719.1|  474|Homo sapiens GABRB2 protein protein.
          Length = 474

 Score = 29.5 bits (63), Expect = 7.2
 Identities = 23/85 (27%), Positives = 37/85 (43%), Gaps = 7/85 (8%)
 Frame = +2

Query: 17  FLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHLRHAN-I 175
           F L  A   A    + +++SL+   +D LL  YD    PD     + V + + +   + +
Sbjct: 15  FPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMV 74

Query: 176 REXESTVRILADLQMNWIDKRLSWN 250
            E      +    Q  W DKRLS+N
Sbjct: 75  SEVNMDYTLTMYFQQAWRDKRLSYN 99


>BC099705-1|AAH99705.1|  474|Homo sapiens GABRB2 protein protein.
          Length = 474

 Score = 29.5 bits (63), Expect = 7.2
 Identities = 23/85 (27%), Positives = 37/85 (43%), Gaps = 7/85 (8%)
 Frame = +2

Query: 17  FLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHLRHAN-I 175
           F L  A   A    + +++SL+   +D LL  YD    PD     + V + + +   + +
Sbjct: 15  FPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMV 74

Query: 176 REXESTVRILADLQMNWIDKRLSWN 250
            E      +    Q  W DKRLS+N
Sbjct: 75  SEVNMDYTLTMYFQQAWRDKRLSYN 99


>AK122582-1|BAC56923.1| 1383|Homo sapiens FLJ00269 protein protein.
          Length = 1383

 Score = 29.5 bits (63), Expect = 7.2
 Identities = 13/38 (34%), Positives = 18/38 (47%)
 Frame = -1

Query: 366 HGRGERSPRRWLQPRLAVPXQASTSVPRTPAKCCSPIP 253
           HG  + SP  W Q + + P +     P  P +CCS  P
Sbjct: 256 HGGRDCSPTCWEQGKCSGPAEQEKRGPSFPKECCSQGP 293


>X55019-1|CAA38759.1|  517|Homo sapiens acetylcholine receptor delta
           subunit protein.
          Length = 517

 Score = 29.1 bits (62), Expect = 9.5
 Identities = 17/55 (30%), Positives = 28/55 (50%), Gaps = 5/55 (9%)
 Frame = +2

Query: 104 YDRESPP----DSKIVVNLTLHLRHA-NIREXESTVRILADLQMNWIDKRLSWNA 253
           Y++E  P    +  + V L L L +  +++E E T+     ++  W D RL WNA
Sbjct: 38  YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNA 92


>M59216-1|AAA35862.1|  474|Homo sapiens gamma-aminobutyric acid
           receptor beta-1 subunit protein.
          Length = 474

 Score = 29.1 bits (62), Expect = 9.5
 Identities = 20/80 (25%), Positives = 34/80 (42%), Gaps = 4/80 (5%)
 Frame = +2

Query: 23  LTCAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IREXES 190
           + C   S  E  N + +   +D LL  YD    PD     + V + + +   + + E   
Sbjct: 21  MVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNM 80

Query: 191 TVRILADLQMNWIDKRLSWN 250
              +    Q +W DKRLS++
Sbjct: 81  DYTLTMYFQQSWKDKRLSYS 100


>BC093925-1|AAH93925.1|  517|Homo sapiens cholinergic receptor,
           nicotinic, delta protein.
          Length = 517

 Score = 29.1 bits (62), Expect = 9.5
 Identities = 17/55 (30%), Positives = 28/55 (50%), Gaps = 5/55 (9%)
 Frame = +2

Query: 104 YDRESPP----DSKIVVNLTLHLRHA-NIREXESTVRILADLQMNWIDKRLSWNA 253
           Y++E  P    +  + V L L L +  +++E E T+     ++  W D RL WNA
Sbjct: 38  YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNA 92


>BC093923-1|AAH93923.1|  517|Homo sapiens cholinergic receptor,
           nicotinic, delta protein.
          Length = 517

 Score = 29.1 bits (62), Expect = 9.5
 Identities = 17/55 (30%), Positives = 28/55 (50%), Gaps = 5/55 (9%)
 Frame = +2

Query: 104 YDRESPP----DSKIVVNLTLHLRHA-NIREXESTVRILADLQMNWIDKRLSWNA 253
           Y++E  P    +  + V L L L +  +++E E T+     ++  W D RL WNA
Sbjct: 38  YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNA 92


>BC022449-1|AAH22449.1|  474|Homo sapiens gamma-aminobutyric acid
           (GABA) A receptor, beta 1 protein.
          Length = 474

 Score = 29.1 bits (62), Expect = 9.5
 Identities = 20/80 (25%), Positives = 34/80 (42%), Gaps = 4/80 (5%)
 Frame = +2

Query: 23  LTCAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IREXES 190
           + C   S  E  N + +   +D LL  YD    PD     + V + + +   + + E   
Sbjct: 21  MVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNM 80

Query: 191 TVRILADLQMNWIDKRLSWN 250
              +    Q +W DKRLS++
Sbjct: 81  DYTLTMYFQQSWKDKRLSYS 100


>AC092165-2|AAY24102.1|  517|Homo sapiens unknown protein.
          Length = 517

 Score = 29.1 bits (62), Expect = 9.5
 Identities = 17/55 (30%), Positives = 28/55 (50%), Gaps = 5/55 (9%)
 Frame = +2

Query: 104 YDRESPP----DSKIVVNLTLHLRHA-NIREXESTVRILADLQMNWIDKRLSWNA 253
           Y++E  P    +  + V L L L +  +++E E T+     ++  W D RL WNA
Sbjct: 38  YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNA 92


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 75,880,261
Number of Sequences: 237096
Number of extensions: 1559132
Number of successful extensions: 3876
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 3738
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3875
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4820001670
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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